VenusViroHub/DMS_substitutions.csv

DMS_id,DMS_filename,virus,protein,phenotype,aa_seq,seq_len,reference,source_lab,pub_status,note,backbone_group,function_group
LASSA_GP_Carr,LASSA_GP_Carr.csv,Lassa virus,GP,cell entry,MGQIVTFFQEVPHVIEEVMNIVLIALSVLAVLKGLYNFATCGLVGLVTFLLLCGRSCTTSLYKGVYELQTLELNMETLNMTMPLSCTKNNSHHYIMVGNETGLELTLTNTSIINHKFCNLSDAHKKNLYDHALMSIISTFHLSIPNFNQYEAMSCDFNGGKISVQYNLSHSYAGDAANHCGTVANGVLQTFMRMAWGGSYIALDSGRGNWDCIMTSYQYLIIQNTTWEDHCQFSRPSPIGYLGLLSQRTRDIYISRRLLGTFTWTLSDSEGKDTPGGYCLTRWMLIEAELKCFGNTAVAKCNEKHDEEFCDMLRLFDFNKQAIQRLKAEAQMSIQLINKAVNALINDQLIMKNHLRDIMGIPYCNYSKYWYLNHTTTGRTSLPKCWLVSNGSYLNETHFSDDIEQQADNMITEMLQKEYMERQGKTPLGLVDLFVFSTSFYLISIFLHLVKIPTHRHIVGKSCPKPHRLNHMGICSCGLYKQPGVPVKWKR,491,"Carr et al., 2024",Bloom lab (dms-vep),preprint,phenotype relabeled fitness->cell entry (source = 293T entry selection),LASSA_GP,cell_entry
SARS2_PLPRO_Wu_abundance,SARS2_PLPRO_Wu_abundance.csv,SARS-CoV-2,PLpro,abundance,MEVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIK,316,"Wu et al., 2024",other,journal,,SARS2_PLPRO,expression
SARS2_PLPRO_Wu_activity,SARS2_PLPRO_Wu_activity.csv,SARS-CoV-2,PLpro,activity,MEVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIK,316,"Wu et al., 2024",other,journal,,SARS2_PLPRO,activity
SARS2_PRD0038_RBD_Starr,SARS2_PRD0038_RBD_Starr.csv,Bat coronavirus PRD0038,RBD,expression,MKFFILLSLLPFATAQEGCGILSNKSKPALTQYSSSRRGFYYFDDTFRSSVRVLTTGYFLPFNSNLTGYSSRNAVTGRLIQFDNPNIPFKDGLYFAATERSNVIRGWIFGSTLDNTTQSAVLFNNGTHIVINVCNFYFCQDPMLTVANGSHYKSWVFLNATNCTYNRVHAFEIDPSLNTGAFIHLREHVFRNVDGFLYVYHNYERANVYDNFPSGFSVLKPILKLPFGLNITQFKVIMTLFSPTTSSFNADASVYFVGHLKPLTMLAEFDENGTITDAVDCSQDPLSELKCTTKSLTVEKGIYQTSNFRVSPSTEVVRFPNITNLCPFGQVFNASKFPSVYAWERLRISDCVADYSVLYNSSSSFSTFKCYGVSPTKLNDLCFSSVYADYFVVKGDDVRQIAPAQTGVIADYNYKLPDDFTGCVLAWNTNSVDSKQGNNFYYRLFRHGKIKPYERDISNVLYNSAGGTCSSTSQLGCYEPLKSYGFTPTVGVGYQPYRVVVLSFELLNAPATVCGPKKSTELVKNKCVNFNFNGLTGTGVLTSSTKKFQPFQQFGRDVSDFTDSVRDPKTLEILDISPCSYGGVSVITPGTNTSKAVAVLYQDVNCTDVPTMLHVEQVSTDWRVYALSADGNMFQTQAGCLVGATYENSTYECDIPIGAGICAKFGSNKLRLESIVAYTMSIGEDQSIAYSNNTIAIPTNFSISVTTEVLPVSMTKTSVDCNMYICGDSTECSNLLLQYGSFCTQLNRALSGIAVEQDRNTRDVFAQTKAIYKTPNIKDFGGFNFSQILPDPKKPSYRSFIEDLLYNKVTLSDPGFMKQYGDCLGGINARDLICAQKFNGLTVLPPLLTDDMIAAYTAALISGTATAGYTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKQIANQFNNAISKIQDSLTTTSAALGKLQDVINQNAVALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQAAPHGVVFLHVTYVPSQQQNFTTAPAICHNGKAYFPREGVFVMNGTHWFITQRNFYSPQVITTDNTFESGSCDVVIGIVNNTVYDPLQPELESFKQELDKYFKNHTSPDVDLGDISGINASVVDIKKEIAHLNEIAKNLNESLIDLQELGKYEQYVKWPWYVWLGFVAGIVAILMSVIMLCCMTNCCSCFKGMCSCGSCCKFDEDHSEPILKGVKLHYP,1256,"Starr et al., 2022",Bloom lab (jbloomlab),journal,,PRD0038_RBD,expression
RmYN02_RBD_Starr,RmYN02_RBD_Starr.csv,Bat coronavirus RmYN02,RBD,expression,MFILLLIGYTAATTCVTGPTTENKQNVSSLMRGVYYPDDIYRSNVNVLFTVPFLRFNSTLTWYNFWNQAYTSRVMEFGDGIYFSTVDKSNAVRGWIFGTTLDNTTQSALLINNGSLVTIQVCYFQFCANPAFLVAGGQQTSAAVYISSHNCTYSEVLSHISLDFTEDTGSFKRLREFVFKNNDGFLHIYGAYEPHVIGIGVTPSLPSTFKPLIPLWKLPLGLNITNFKVVLTFRSNSQPLQANFAVGSLKLTTFMLSFDINGTIDKAVDCSSDPLSELKCTLKSFNVSKGIYPTSNFRVLPSTEVVRFPNITNFCPFDKVFNATRFPNVYAWQRTKISDCIADYTVLYNSTSFSTFKCYGVSPSKLIDLCFTSVYADTFLIRFSEVRQIAPGETGVIADYNYKLPDDFTGCVLAWNTAQQDIGSYFYRSHRAVKLKPFERDLSSDENGVRTLSTYDFNPNVPLDYQATRVVVLSFELLNAPATVCGPKLST,491,"Starr et al., 2022",Bloom lab (jbloomlab),journal,,RmYN02_RBD,expression
RsYN04_RBD_Starr,RsYN04_RBD_Starr.csv,Bat coronavirus RsYN04,RBD,expression,MFILLLLPIVLAQQDSCNHIVQLPNSMVRGVYNSGSKVYYPDDINRVSTSILFNDYFLPFNSNLTNRQTLGNTNNNRFDVFTEPFLDGVYFAATEHSNVLRGWIFGTSFTNTTQSALFYNNGTNVVIEVCNFNFCLVPRVHALPNGSSISYIYTSKANCTYTYVSQSFSLNGAICSSNCDKFKDFREFIFKYSEGFLHVYSGYKAISQGNGFVPSFSALKPFGKFPIGILVTNFSVILTSFYHDSTTTKLAASSLFYGHLRPITMLLQYDENGTIYNAIDCSQDPLSELKCSLKAVNVSKGIYQTSNFRVTPSQSVARYPNITNLCPFSQVFNATRFPSVYAWTRERISNCIADYSVLYNSTSFSTFRCYGVSPTKLNDLCFSNVYADSMVVRGDEVRQIAPSQTGVIADYNYKLPDDFTGCVIAWNSKAKDENGQYFYRLFRKSKLLPFQRDVSNVTYGSGKNDGCNPSEADCYWPLLKYGFTSSVSQDYQPYRVVVLSFELLNAPATVCGPKRST,517,"Starr et al., 2022",Bloom lab (jbloomlab),journal,,RsYN04_RBD,expression
SARS2_BA1_SPIKE_Dadonaite,SARS2_BA1_SPIKE_Dadonaite.csv,SARS-CoV-2,Spike,fitness,MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHVISGTNGTKRFDNPVLPFNDGVYFASIEKSNIIRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLDHKNNKSWMESEFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPIIVREPEDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFDEVFNATRFASVYAWNRKRISNCVADYSVLYNLAPFFTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGNIADYNYKLPDDFTGCVIAWNSNKLDSKVSGNYNYLYRLFRKSNLKPFERDISTEIYQAGNKPCNGVAGFNCYFPLRSYSFRPTYGVGHQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLKGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQGVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEYVNNSYECDIPIGAGICASYQTQTKSHRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLKRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKYFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFKGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNHNAQALNTLVKQLSSKFGAISSVLNDIFSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKWPWYIWLGFIAGLIAIVMVTIMLCCMTSCCSCLKGCCSCGS,1249,"Dadonaite et al., 2024",Bloom lab (dms-vep),journal,,SARS2_SPIKE,fitness
SARS2_DELTA_SPIKE_Dadonaite,SARS2_DELTA_SPIKE_Dadonaite.csv,SARS-CoV-2,Spike,fitness,MFVFLVLLPLVSSQCVNLRTRTQLPPAYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFDNPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLDVYYHKNNKSWMESGVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINLVRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYRYRLFRKSNLKPFERDISTEIYQAGSKPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQGVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNNSYECDIPIGAGICASYQTQTNSRRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQNVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKWPWYIWLGFIAGLIAIVMVTIMLCCMTSCCSCLKGCCSCGS,1250,"Dadonaite et al., 2024",Bloom lab (dms-vep),journal,,SARS2_SPIKE,fitness
IAV_H5_HA_Dadonaite,IAV_H5_HA_Dadonaite.csv,Influenza A H5N1,HA,cell entry,MENIVLLLAIVSLVKSDQICIGYHANNSTEQVDTIMEKNVTVTHAQDILEKTHNGKLCDLNGVKPLILKDCSVAGWLLGNPMCDEFIRVPEWSYIVERANPANDLCYPGSLNDYEELKHMLSRINHFEKILIIPKSSWPNHETSLGVSAACPYQGAPSFFRNVVWLIKKNDAYPTIKISYNNTNREDLLILWGIHHSNNAEEQTNLYKNPTTYISVGTSTLNQRLAPKIATRSQVNGQRGRMDFFWTILKPDDAIHFESNGNFIAPEYAYKIVKKGDSTIMKSGVEYGHCNTKCQTPVGAINSSMPFHNIHPLTIGECPKYVKSNKLVLATGLRNSPLREKRRKRGLFGAIAGFIEGGWQGMVDGWYGYHHSNEQGSGYAADKESTQKAIDGVTNKVNSIIDKMNTQFEAVGREFNNLERRIENLNKKMEDGFLDVWTYNAELLVLMENERTLDFHDSNVKNLYDKVRLQLRDNAKELGNGCFEFYHKCDNECMESVRNGTYDYPQYSEEARLKREEISGVKLESVGTYQILSIYSTAASSLALAIMMAGLSLWMCSNGSLQCRICI,567,"Dadonaite et al., 2024a",Bloom lab (dms-vep),journal,phenotype relabeled fitness->cell entry (source = entry in 293T cells),IAV_H5_HA,cell_entry
NIPAH_F_Larsen,NIPAH_F_Larsen.csv,Nipah virus,G (RBP),cell entry,MPAENKKVRFENTTSDKGKIPSKVIKSYYGTMDIKKINEGLLDSKILSAFNTVIALLGSIVIIVMNIMIIQNYTRSTDNQAVIKDALQGIQQQIKGLADKIGTEIGPKVSLIDTSSTITIPANIGLLGSKISQSTASINENVNEKCKFTLPPLKIHECNISCPNPLPFREYRPQTEGVSNLVGLPNNICLQKTSNQILKPKLISYTLPVVGQSGTCITDPLLAMDEGYFAYSHLERIGSCSRGVSKQRIIGVGEVLDRGDEVPSLFMTNVWTPPNPNTVYHCSAVYNNEFYYVLCAVSTVGDPILNSTYWSGSLMMTRLAVKPKSNGGGYNQHQLALRSIEKGRYDKVMPYGPSGIKQGDTLYFPAVGFLVRTEFKYNDSNCPITKCQYSKPENCRLSMGIRPNSHYILRSGLLKYNLSDGENPKVVFIEISDQRLSIGSPSKIYDSLGQPVFYQASFSWDTMIKFGDVLTVNPLVVNWRNNTVISRPGQSQCPRFNTCPEICWEGVYNDAFLIDRINWISAGVFLDSNQTAENPVFTVFKDNEILYRAQLASEDTNAQKTITNCFLLKNKIWCISLVEIYDTGDNVIRPKLFAVKIPEQCT,602,"Larsen et al., 2025",Bloom lab (dms-vep),preprint,"mislabeled in original viro: data is Nipah G/RBP CHO-bEFNB2 cell entry (Larsen 2025 RBP DMS), not F fitness; id kept for compatibility",NIPAH_RBP,cell_entry
CVB3_2A_Alvarez,CVB3_2A_Alvarez.csv,Coxsackievirus B3,2A,fitness,GAFGQQSGAVYVGNYRVVNRHLATSADWQNCVWESYNRDLLVSTTTAHGCDIIARCQCTTGVYFCASKNKHYPISFEGPGLVEVQESEYYPRRYQSHVLLAAGFSEPGDCGGILRCEHGVIGIVTMGGEGVVGFADIRDLLWLEDDAMEQ,150,"Alvarez-Rodriguez et al., 2024",Geller lab (ISMMS),journal,,CVB3_2A,fitness
CVB3_2B_Alvarez,CVB3_2B_Alvarez.csv,Coxsackievirus B3,2B,fitness,GVKDYVEQLGNAFGSGFTNQICEQVNLLKESLVGQDSILEKSLKALVKIISALVIVVRNHDDLITVTATLALIGCTSSPWRWLKQKVSQYYGIPMAERQ,99,"Alvarez-Rodriguez et al., 2024",Geller lab (ISMMS),journal,,CVB3_2B,fitness
CVB3_2C_Alvarez,CVB3_2C_Alvarez.csv,Coxsackievirus B3,2C,fitness,NNSWLKKFTEMTNACKGMEWIAVKIQKFIEWLKVKILPEVREKHEFLNRLKQLPLLESQIATIEQSAPSQSDQEQLFSNVQYFAHYCRKYAPLYAAEAKRVFSLEKKMSNYIQFKSKCRIEPVCLLLHGSPGAGKSVATNLIGRSLAEKLNSSVYSLPPDPDHFDGYKQQAVVIMDDLCQNPDGKDVSLFCQMVSSVDFVPPMAALEEKGILFTSPFVLASTNAGSINAPTVSDSRALARRFHFDMNIEVISMYSQNGKINMPMSVKTCDDECCPVNFKKCCPLVCGKAIQFIDRRTQVRYSLDMLVTEMFREYNHRHSVGTTLEALFQ,329,"Alvarez-Rodriguez et al., 2024",Geller lab (ISMMS),journal,,CVB3_2C,fitness
CVB3_3A_Alvarez,CVB3_3A_Alvarez.csv,Coxsackievirus B3,3A,fitness,GPPVYREIKISVAPETPPPPAIADLLKSVDSEAVREYCKEKGWLVPEINSTLQIEKHVSRAFICLQALTTFVSVAGIIYIIYKLFAGFQ,89,"Alvarez-Rodriguez et al., 2024",Geller lab (ISMMS),journal,,CVB3_3A,fitness
CVB3_3B_Alvarez,CVB3_3B_Alvarez.csv,Coxsackievirus B3,3B,fitness,GAYTGVPNQKPRVPTLRQAKVQ,22,"Alvarez-Rodriguez et al., 2024",Geller lab (ISMMS),journal,,CVB3_3B,fitness
CVB3_3C_Alvarez,CVB3_3C_Alvarez.csv,Coxsackievirus B3,3C,fitness,GPAFEFAVAMMKRNSSTVKTEYGEFTMLGIYDRWAVLPRHAKPGPTILMNDQEVGVLDAKELVDKDGTNLELTLLKLNRNEKFRDIRGFLAKEEVEVNEAVLAINTSKFPNMYIPVGQVTEYGFLNLGGTPTKRMLMYNFPTRAGQCGGVLMSTGKVLGIHVGGNGHQGFSAALLKHYFNDEQ,183,"Alvarez-Rodriguez et al., 2024",Geller lab (ISMMS),journal,,CVB3_3C,fitness
CVB3_3D_Alvarez,CVB3_3D_Alvarez.csv,Coxsackievirus B3,3D,fitness,GEIEFIESSKDAGFPVINTPSKTKLEPSVFHQVFEGNKEPAVLRSGDPRLKANFEEAIFSKYIGNVNTHVDEYMLEAVDHYAGQLATLDISTEPMKLEDAVYGTEGLEALDLTTSAGYPYVALGIKKRDILSKKTKDLTKLKECMDKYGLNLPMVTYVKDELRSIEKVAKGKSRLIEASSLNDSVAMRQTFGNLYKTFHLNPGVVTGSAVGCDPDLFWSKIPVMLDGHLIAFDYSGYDASLSPVWFACLKMLLEKLGYTHKETNYIDYLCNSHHLYRDKHYFVRGGMPSGCSGTSIFNSMINNIIIRTLMLKVYKGIDLDQFRMIAYGDDVIASYPWPIDASLLAEAGKGYGLIMTPADKGECFNEVTWTNATFLKRYFRADEQYPFLVHPVMPMKDIHESIRWTKDPKNTQDHVRSLCLLAWHNGEHEYEEFIRKIRSVPVGRCLTLPAFSTLRRKWLDSF,462,"Alvarez-Rodriguez et al., 2024",Geller lab (ISMMS),journal,,CVB3_3D,fitness
CVB3_VP1_Alvarez,CVB3_VP1_Alvarez.csv,Coxsackievirus B3,VP1,fitness,GPVEDAITAAIGRVADTVGTGPTNSEAIPALTAAETGHTSQVVPGDTMQTRHVKNYHSRSESTIENFLCRSACVYFTEYKNSGAKRYAEWVLTPRQAAQLRRKLEFFTYVRFDLELTFVITSTQQPSTTQNQDAQILTHQIMYVPPGGPVPDKVDSYVWQTSTNPSVFWTEGNAPPRMSIPFLSIGNAYSNFYDGWSEFSRNGVYGINTLNNMGTLYARHVNAGSTGPIKSTIRIYFKPKHVKAWIPRPPRLCQYEKAKNVNFQPSGVTTTRQSITTMTNT,281,"Alvarez-Rodriguez et al., 2024",Geller lab (ISMMS),journal,,CVB3_VP1,fitness
CVB3_VP3_Alvarez,CVB3_VP3_Alvarez.csv,Coxsackievirus B3,VP3,fitness,GLPTMNTPGSCQFLTSDDFQSPSAMPQYDVTPEMRIPGEVKNLMEIAEVDSVVPVQNVGEKVNSMEAYQIPVRSNEGSGTQVFGFPLQPGYSSVFSRTLLGEILNYYTHWSGSIKLTFMFCGSAMATGKFLLAYSPPGAGAPTKRVDAMLGTHVIWDVGLQSSCVLCIPWISQTHYRFVASDEYTAGGFITCWYQTNIVVPADAQSSCYIMCFVSACNDFSVRLLKDTPFISQQNFFQ,238,"Alvarez-Rodriguez et al., 2024",Geller lab (ISMMS),journal,,CVB3_VP3,fitness
EV_CAPSD_Bakhache,EV_CAPSD_Bakhache.csv,Enterovirus A,Capsid,fitness,MGSQVSTQRSGSHENSNSATEGSTINYTTINYYKDSYAATAGKQSLKQDPDKFANPVKDIFTEMAAPLKSPSAEACGYSDRVAQLTIGNSTITTQEAANIIVGYGEWPSYCSDSDATAVDKPTRPDVSVNRFYTLDTKLWEKSSKGWYWKFPDVLTETGVFGQNAQFHYLYRSGFCIHVQCNASKFHQGALLVAVLPEYVIGTVAGGTGTEDSHPPYKQTQPGADGFELQHPYVLDAGIPISQLTVCPHQWINLRTNNCATIIVPYINALPFDSALNHCNFGLLVVPISPLDYDQGATPVIPITITLAPMCSEFAGLRQAVTQGFPTELKPGTNQFLTTDDGVSAPILPNFHPTPCIHIPGEVRNLLELCQVETILEVNNVPTNATSLMERLRFPVSAQAGKGELCAVFRADPGRSGPWQSTLLGQLCGYYTQWSGSLEVTFMFTGSFMATGKMLIAYTPPGGPLPKDRATAMLGTHVIWDFGLQSSVTLVIPWISNTHYRAHARDGVFDYYTTGLVSIWYQTNYVVPIGAPNTAYIIALAAAQKNFTMKLCKDASDILQTGTIQGDRVADVIESSIGDSVSRALTRALPAPTGQDTQVSSHRLDTGKVPALQAAEIGASSNASDESMIETRCVLNSHSTAETTLDSFFSRAGLVGEIDLPLEGTTNPNGYANWDIDITGYAQMRRKVELFTYMRFDAEFTFVACTPTGQVVPQLLQYMFVPPGAPKPDSRESLAWQTATNPSVFVKLSDPPAQVSVPFMSPASAYQWFYDGYPTFGEHKQEKDLEYGACPNNMMGTFSVRTVGTSKSKYPLVIRIYMRMKHVRAWIPRPMRNQNYLFKANPNYAGNFIKPTGASRTAITTL,862,"Bakhache et al., 2024",other,journal,,EV_CAPS,fitness
EV_REP_Bakhache,EV_REP_Bakhache.csv,Enterovirus A,Replicase,fitness,GKFGQQSGAIYVGNFRVVNRHLATHNDWANLVWEDSSRDLLVSSTTAQGCDTIARCNCQTGVYYCNSMRKHYPVSFSKPSLIFVEASEYYPARYQSHLMLAVGHSEPGDCGGILRCQHGVVGIVSTGGNGLVGFADVRDLLWLDDEAMEQGVSDYIKGLGDAFGMGFTDAVSREVEALKSHLIGSEGAVEKILKNLVKLISALVIVIRSDYDMVTLTATLALIGCHGSPWAWVKSKTASILGIPMAQKQSASWLKKFNDAASAAKGLEWISNKISKFIDWLKEKIIPAAKEKVEFLNNLKQLPLLENQISNLEQSAASQEDLEAMFGNVSYLAHFCRKFQPLYATEAKRVYALEKRMNNYMQFKSKHRIEPVCLIIRGSPGTGKSLATGIIARAIADKYHSSVYSLPPDPDHFDGYKQQIVTVMDDLCQNPDGKDMSLFCQMVSTVDFIPPMASLEEKGVSFTSKFVIASTNASNIIVPTVSDSDAIRRRFFMDCDIEVTDSYKTELGRLDAGRAARLCSENNTANFKRCSPLVCGKAIQLRDRKSKVRYSVDTVVSELIREYNNRSVIGNTIEALFQGPPKFRPIRISLEEKPAPDAISDLLASVDSEEVRQYCRDQGWIVPDSPTNVERHLNRAVLIMQSVATVVAVVSLVYVIYKLFAGFQGAYSGAPKQTLKKPVLRTATVQGPSLDFALSLLRRNIRQVQTDQGHFTMLGVRDRLAVLPRHSQPGKTIWVEHKLVKIVDAVELVDEQGVNLELTLVTLDTNEKFRDITRFIPETISPASDATLVINTEHMPSMFVPVGDVVQYGFLNLSGKPTHRTMMYNFPTKAGQCGGVVTAVGKVIGIHIGGNGRQGFCAALKRGYFCSEQGEIQWMKPNKETGRLNINGPTRTKLEPSVFHDVFEGTKEPAVLTSKDPRLEVDFEQALFSKYVGNTLHEPDEFVKEAALHYANQLKQLDIKTTKMSMEDACYGTENLEAIDLHTSAGYPYSALGIKKKDILDPTTRDVSKMKFYMDKYGLDLPYSTYVKDELRAIDKIKKGKSRLIEASSLNDSVYLRMTFGHLYEAFHANPGTITGSAVGCNPDVFWSKLPILLPGSLFAFDYSGYDASLSPVWFRALEIVLREIGYSEDAVSLIEGINHTHHVYRNKTYCVLGGMPSGCSGTSIFNSMINNIIIRTLLIKTFKGIDLDELNMVAYGDDVLASYPFPIDCLELARTGKEYGLTMTPADKSPCFNEVTWENATFLKRGFLPDHQFPFLIHPTMPMREIHESIRWTKDARSTQDHVRSLCLLAWHNGKEEYEKFVSAIRSVPIGKALAIPNYENLRRNWLELF,1331,"Bakhache et al., 2024",other,journal,,EV_REP,fitness
SARS2_RBD_Beta_binding,SARS2_RBD_Beta_binding.csv,SARS-CoV-2,RBD,binding,NITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGNIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVKGFNCYFPLQSYGFQPTYGVGYQPYRVVVLSFELLHAPATVCGPKKST,201,"Starr et al., 2022a",Bloom lab (jbloomlab),journal,,SARS2_RBD,binding
SARS2_RBD_Beta_expression,SARS2_RBD_Beta_expression.csv,SARS-CoV-2,RBD,expression,NITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGNIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVKGFNCYFPLQSYGFQPTYGVGYQPYRVVVLSFELLHAPATVCGPKKST,201,"Starr et al., 2022a",Bloom lab (jbloomlab),journal,,SARS2_RBD,expression
SARS2_RBD_Delta_binding,SARS2_RBD_Delta_binding.csv,SARS-CoV-2,RBD,binding,NITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYRYRLFRKSNLKPFERDISTEIYQAGSKPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKST,201,"Starr et al., 2022a",Bloom lab (jbloomlab),journal,,SARS2_RBD,binding
SARS2_RBD_Delta_expression,SARS2_RBD_Delta_expression.csv,SARS-CoV-2,RBD,expression,NITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYRYRLFRKSNLKPFERDISTEIYQAGSKPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKST,201,"Starr et al., 2022a",Bloom lab (jbloomlab),journal,,SARS2_RBD,expression
SARS2_RBD_Alpha_binding,SARS2_RBD_Alpha_binding.csv,SARS-CoV-2,RBD,binding,NITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTYGVGYQPYRVVVLSFELLHAPATVCGPKKST,201,"Starr et al., 2022b",Bloom lab (jbloomlab),journal,,SARS2_RBD,binding
SARS2_RBD_Alpha_expression,SARS2_RBD_Alpha_expression.csv,SARS-CoV-2,RBD,expression,NITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTYGVGYQPYRVVVLSFELLHAPATVCGPKKST,201,"Starr et al., 2022b",Bloom lab (jbloomlab),journal,,SARS2_RBD,expression
SARS2_RBD_Eta_binding,SARS2_RBD_Eta_binding.csv,SARS-CoV-2,RBD,binding,NITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVKGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKST,201,"Starr et al., 2022b",Bloom lab (jbloomlab),journal,,SARS2_RBD,binding
SARS2_RBD_Eta_expression,SARS2_RBD_Eta_expression.csv,SARS-CoV-2,RBD,expression,NITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVKGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKST,201,"Starr et al., 2022b",Bloom lab (jbloomlab),journal,,SARS2_RBD,expression
SARS2_RBD_Omicron_BA1_binding,SARS2_RBD_Omicron_BA1_binding.csv,SARS-CoV-2,RBD,binding,NITNLCPFDEVFNATRFASVYAWNRKRISNCVADYSVLYNLAPFFTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGNIADYNYKLPDDFTGCVIAWNSNKLDSKVSGNYNYLYRLFRKSNLKPFERDISTEIYQAGNKPCNGVAGFNCYFPLRSYSFRPTYGVGHQPYRVVVLSFELLHAPATVCGPKKST,201,"Starr et al., 2022b",Bloom lab (jbloomlab),journal,,SARS2_RBD,binding
SARS2_RBD_Omicron_BA1_expression,SARS2_RBD_Omicron_BA1_expression.csv,SARS-CoV-2,RBD,expression,NITNLCPFDEVFNATRFASVYAWNRKRISNCVADYSVLYNLAPFFTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGNIADYNYKLPDDFTGCVIAWNSNKLDSKVSGNYNYLYRLFRKSNLKPFERDISTEIYQAGNKPCNGVAGFNCYFPLRSYSFRPTYGVGHQPYRVVVLSFELLHAPATVCGPKKST,201,"Starr et al., 2022b",Bloom lab (jbloomlab),journal,,SARS2_RBD,expression
SARS2_RBD_Omicron_BA2_binding,SARS2_RBD_Omicron_BA2_binding.csv,SARS-CoV-2,RBD,binding,NITNLCPFDEVFNATRFASVYAWNRKRISNCVADYSVLYNFAPFFAFKCYGVSPTKLNDLCFTNVYADSFVIRGNEVSQIAPGQTGNIADYNYKLPDDFTGCVIAWNSNKLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGNKPCNGVAGFNCYFPLRSYGFRPTYGVGHQPYRVVVLSFELLHAPATVCGPKKST,201,"Starr et al., 2022b",Bloom lab (jbloomlab),journal,,SARS2_RBD,binding
SARS2_RBD_Omicron_BA2_expression,SARS2_RBD_Omicron_BA2_expression.csv,SARS-CoV-2,RBD,expression,NITNLCPFDEVFNATRFASVYAWNRKRISNCVADYSVLYNFAPFFAFKCYGVSPTKLNDLCFTNVYADSFVIRGNEVSQIAPGQTGNIADYNYKLPDDFTGCVIAWNSNKLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGNKPCNGVAGFNCYFPLRSYGFRPTYGVGHQPYRVVVLSFELLHAPATVCGPKKST,201,"Starr et al., 2022b",Bloom lab (jbloomlab),journal,,SARS2_RBD,expression
SARS2_RBD_Omicron_BQ11_binding,SARS2_RBD_Omicron_BQ11_binding.csv,SARS-CoV-2,RBD,binding,NITNLCPFDEVFNATTFASVYAWNRKRISNCVADYSVLYNFAPFFAFKCYGVSPTKLNDLCFTNVYADSFVIRGNEVSQIAPGQTGNIADYNYKLPDDFTGCVIAWNSNKLDSTVGGNYNYRYRLFRKSKLKPFERDISTEIYQAGNKPCNGVAGVNCYFPLQSYGFRPTYGVGHQPYRVVVLSFELLHAPATVCGPKKST,201,"Taylor & Starr, 2023",Bloom lab (jbloomlab),journal,,SARS2_RBD,binding
SARS2_RBD_Omicron_BQ11_expression,SARS2_RBD_Omicron_BQ11_expression.csv,SARS-CoV-2,RBD,expression,NITNLCPFDEVFNATTFASVYAWNRKRISNCVADYSVLYNFAPFFAFKCYGVSPTKLNDLCFTNVYADSFVIRGNEVSQIAPGQTGNIADYNYKLPDDFTGCVIAWNSNKLDSTVGGNYNYRYRLFRKSKLKPFERDISTEIYQAGNKPCNGVAGVNCYFPLQSYGFRPTYGVGHQPYRVVVLSFELLHAPATVCGPKKST,201,"Taylor & Starr, 2023",Bloom lab (jbloomlab),journal,,SARS2_RBD,expression
SARS2_RBD_Omicron_XBB15_binding,SARS2_RBD_Omicron_XBB15_binding.csv,SARS-CoV-2,RBD,binding,NITNLCPFHEVFNATTFASVYAWNRKRISNCVADYSVIYNFAPFFAFKCYGVSPTKLNDLCFTNVYADSFVIRGNEVSQIAPGQTGNIADYNYKLPDDFTGCVIAWNSNKLDSKPSGNYNYLYRLFRKSKLKPFERDISTEIYQAGNKPCNGVAGPNCYSPLQSYGFRPTYGVGHQPYRVVVLSFELLHAPATVCGPKKST,201,"Taylor & Starr, 2023",Bloom lab (jbloomlab),journal,,SARS2_RBD,binding
SARS2_RBD_Omicron_XBB15_expression,SARS2_RBD_Omicron_XBB15_expression.csv,SARS-CoV-2,RBD,expression,NITNLCPFHEVFNATTFASVYAWNRKRISNCVADYSVIYNFAPFFAFKCYGVSPTKLNDLCFTNVYADSFVIRGNEVSQIAPGQTGNIADYNYKLPDDFTGCVIAWNSNKLDSKPSGNYNYLYRLFRKSKLKPFERDISTEIYQAGNKPCNGVAGPNCYSPLQSYGFRPTYGVGHQPYRVVVLSFELLHAPATVCGPKKST,201,"Taylor & Starr, 2023",Bloom lab (jbloomlab),journal,,SARS2_RBD,expression
SARS2_RBD_Omicron_BA286_binding,SARS2_RBD_Omicron_BA286_binding.csv,SARS-CoV-2,RBD,binding,NVTNLCPFHEVFNATRFASVYAWNRTRISNCVADYSVLYNFAPFFAFKCYGVSPTKLNDLCFTNVYADSFVIKGNEVSQIAPGQTGNIADYNYKLPDDFTGCVIAWNSNKLDSKHSGNYDYWYRLFRKSKLKPFERDISTEIYQAGNKPCKGKGPNCYFPLQSYGFRPTYGVGHQPYRVVVLSFELLHAPATVCGPKKST,200,"Taylor & Starr, 2024",Bloom lab (jbloomlab),journal,,SARS2_RBD,binding
SARS2_RBD_Omicron_BA286_expression,SARS2_RBD_Omicron_BA286_expression.csv,SARS-CoV-2,RBD,expression,NVTNLCPFHEVFNATRFASVYAWNRTRISNCVADYSVLYNFAPFFAFKCYGVSPTKLNDLCFTNVYADSFVIKGNEVSQIAPGQTGNIADYNYKLPDDFTGCVIAWNSNKLDSKHSGNYDYWYRLFRKSKLKPFERDISTEIYQAGNKPCKGKGPNCYFPLQSYGFRPTYGVGHQPYRVVVLSFELLHAPATVCGPKKST,200,"Taylor & Starr, 2024",Bloom lab (jbloomlab),journal,,SARS2_RBD,expression
SARS2_RBD_Omicron_EG5_binding,SARS2_RBD_Omicron_EG5_binding.csv,SARS-CoV-2,RBD,binding,NITNLCPFHEVFNATTFASVYAWNRKRISNCVADYSVIYNFAPFFAFKCYGVSPTKLNDLCFTNVYADSFVIRGNEVSQIAPGQTGNIADYNYKLPDDFTGCVIAWNSNKLDSKPSGNYNYLYRLLRKSKLKPFERDISTEIYQAGNKPCNGVAGPNCYSPLQSYGFRPTYGVGHQPYRVVVLSFELLHAPATVCGPKKST,201,"Taylor & Starr, 2024",Bloom lab (jbloomlab),journal,,SARS2_RBD,binding
SARS2_RBD_Omicron_EG5_expression,SARS2_RBD_Omicron_EG5_expression.csv,SARS-CoV-2,RBD,expression,NITNLCPFHEVFNATTFASVYAWNRKRISNCVADYSVIYNFAPFFAFKCYGVSPTKLNDLCFTNVYADSFVIRGNEVSQIAPGQTGNIADYNYKLPDDFTGCVIAWNSNKLDSKPSGNYNYLYRLLRKSKLKPFERDISTEIYQAGNKPCNGVAGPNCYSPLQSYGFRPTYGVGHQPYRVVVLSFELLHAPATVCGPKKST,201,"Taylor & Starr, 2024",Bloom lab (jbloomlab),journal,,SARS2_RBD,expression
SARS2_RBD_Omicron_FLip_binding,SARS2_RBD_Omicron_FLip_binding.csv,SARS-CoV-2,RBD,binding,NITNLCPFHEVFNATTFASVYAWNRKRISNCVADYSVIYNFAPFFAFKCYGVSPTKLNDLCFTNVYADSFVIRGNEVSQIAPGQTGNIADYNYKLPDDFTGCVIAWNSNKLDSKPSGNYNYLYRFLRKSKLKPFERDISTEIYQAGNKPCNGVAGPNCYSPLQSYGFRPTYGVGHQPYRVVVLSFELLHAPATVCGPKKST,201,"Taylor & Starr, 2024",Bloom lab (jbloomlab),journal,,SARS2_RBD,binding
SARS2_RBD_Omicron_FLip_expression,SARS2_RBD_Omicron_FLip_expression.csv,SARS-CoV-2,RBD,expression,NITNLCPFHEVFNATTFASVYAWNRKRISNCVADYSVIYNFAPFFAFKCYGVSPTKLNDLCFTNVYADSFVIRGNEVSQIAPGQTGNIADYNYKLPDDFTGCVIAWNSNKLDSKPSGNYNYLYRFLRKSKLKPFERDISTEIYQAGNKPCNGVAGPNCYSPLQSYGFRPTYGVGHQPYRVVVLSFELLHAPATVCGPKKST,201,"Taylor & Starr, 2024",Bloom lab (jbloomlab),journal,,SARS2_RBD,expression
HIV_BF520_cell_entry,HIV_BF520_cell_entry.csv,HIV-1,Env BF520,cell entry,MRVKMNSQHLLRWGIMILGMIMICSVAGNLWVTVYYGVPVWKDAETTLFCASDAKAYDAEVHNIWATHACVPTDPNPQEINLENVTEEFNMWKNNMVEQMHTDIISLWDQGLKPCVKLTPLCVTLDCHNVTYNITSDMKEEITNCSYNVTTVIRDKKQKVSSLFYKLDVVQINNRTNSYRLINCNTSAITQACPKVTFEPIPIHYCAPAGFAILKCKDEKFNGTGLCKNVSTVQCTHGIKPVVSTQLLLNGSLAEGEVRIRSENITNNAKNIIVQLASPVTINCIRPNNNTRKSVHLGPGQAFATDGIIGEIRQAHCNVSKKEWNSTLQKVANQLRPYFKNNTIIKFANSSGGDLEITTHSFNCGGEFFYCNTSGLFNSTWFNSTWNNSNSTENITLQCRIKQIINMWQRAGQAIYAPPIPGVIRCKSNITGLILTRDGGSNKNTSETFRPGGGDMRDNWRSELYKYKVVKIEPIGVAPTRAKRRVVEREKRAVGIGAVFIGFLGAAGSTMGAASVTLTVQARQLLSGIVQQQSNLLRAIEAQQHLLKLTVWGIKQLQARVLAVERYLKDQQLLGIWGCSGKLICTTNVPWNSSWSNKSQDEIWGNMTWLQWDKEVSNYTQIIYTLIEESQNQQEKNEQDLLALDKWASLWNWFNISQWLWYIKIFIIIVGGLIGLRIVFAVLSVINRVRQGYSPLSFQTRTPNPGELDRPGRIEEEGGEQDRGRSIRLVSGFLALAWDDLRSLCLFSYHRLRDFILIATRTVELLGRLGWESLKYLGNLLVYWGRELKISAINLCDTIAIAVAGWTDRVIELGQRLCRAILHIPRRIRQGFERALL,837,"Radford & Bloom, 2025",Bloom lab (dms-vep),preprint,,HIV_ENV,cell_entry
HIV_TRO11_cell_entry,HIV_TRO11_cell_entry.csv,HIV-1,Env TRO11,cell entry,MRIRKNCQHLWIWGTMLLGMLMIYSAAEQLWVTVYYGVPVWKDASTTLFCASDAKAYDTEVHNVWATHACVPTDPNPQEVVLGNVTENFNMWKNNMVDQMHEDIISLWDQSLKPCVKLTPLCVTLNCTDNITNTNTNSSKNSSTHSEGEMKNCSFNITAGIRDKVKKEYALFYKLDVVPIDKDTTTYRLRSCNTSVITQACPKVTFEPIPIHYCAPAGFAILKCNDKKFNGTGPCTNVSTVQCTHGIRPVVSTQLLLNGSLAEEEVVIRSENFTNNAKTIIVQLNESIAINCTRPNNNTRRSIHIGPGRAFYATGDIGDIRQAHCNISRTEWNSTLRQIVTKLREQLGDNKTIIFNQSSGGDTEITMHSFNCGGEFFYCNTTKLFNSTWNGNNTTESDSTITLPCRIKQIINLWQEVGKAMYAPPIKGQISCSSNITGLLLTRDGGNNNSSGETFRPGGGNMKDNWRSELYKYKVIKIEPLGVAPTRAKRRVVQREKRAVGLGAMFLGFLGAAGSTMGAASVTLTVQARLLLSGIVQQQNNLLRAIEAQQHMLQLTVWGIKQLQARVLAVERYLRDQQLLGIWGCSGKLICTTNVPWNASWSNKSLNNIWENMTWMEWEREIDNYTDLIYILLEKSQIQQEKNEQELLELDSWASLWNWFDISKWLWYIKIFIMIVGGLVGLRIVFAVLSIANRVRQGYSPLSFQTRLPTPRGPDRPEGIEKEGGGRDRDGSRPLVHGLLALIWDDLRSLCLFSYHRLRDLLLIVTRTVELLGRRGWELLKYWWNLLQYWSQELKNSAVSLLNTTAIAVAEGTDRVIEVVQRAFRAILHIPARIRQGLERALL,843,"Radford & Bloom, 2025",Bloom lab (dms-vep),preprint,,HIV_ENV,cell_entry
IAV_H3_MC22_cell_entry,IAV_H3_MC22_cell_entry.csv,Influenza A H3N2,HA,cell entry,QKIPGNDNSTATLCLGHHAVPNGTIVKTITNDRIEVTNATELVQNSSIGKICNSPHQILDGGNCTLIDALLGDPQCDGFQNKEWDLFVERSRANSSCYPYDVPDYASLRSLVASSGTLEFKNESFNWTGVKQNGTSSACKRGSSSSFFSRLNWLTSLNNIYPAQNVTMPNKEQFDKLYIWGVHHPDTDKNQFSLFAQSSGRITVSTKRSQQAVIPNIGSRPRVRDIPSRISIYWTIVKPGDILLINSTGNLIAPRGYFKIRSGKSSIMRSDAPIGKCKSECITPNGSIPNDKPFQNVNRITYGACPRYVKQSTLKLATGMRNVPEKQTRGIFGAIAGFIENGWEGMVDGWYGFRHQNSEGRGQAADLKSTQAAIDQISGKLNRLIGKTNEKFHQIEKEFSEVEGRVQDLEKYVEDTKIDLWSYNAELLVALENQHTIDLTDSEMNKLFEKTKKQLRENAEDMGNGCFKIYHKCDNACIGSIRNETYDHNVYRDEALNNRFQIKG,504,"Yu et al., 2025",Bloom lab (dms-vep),preprint,,IAV_H3_HA,cell_entry
RABV_G_Aditham_cell_entry,RABV_G_Aditham_cell_entry.csv,Rabies virus,G,cell entry,FGKFPIYTIPDKLGPWSPIDIHHLSCPNNLVVEDEGCTNLSGFSYMELKVGYISAIKMNGFTCTGVVTEAETYTNFVGYVTTTFKRKHFRPTPDACRAAYNWKMAGDPRYEESLHNPYPDYHWLRTVKTTKESLVIISPSVADLDPYDRSLHSRVFPGGNCSGVAVSSTYCSTNHDYTIWMPENPRLGMSCDIFTNSRGKRASKGSETCGFVDERGLYKSLKGACKLKLCGVLGLRLMDGTWVAMQTSNETKWCPPGQLVNLHDFRSDEIEHLVVEELVKKREECLDALESIMTTKSVSFRRLSHLRKLVPGFGKAYTIFNKTLMEADAHYKSVRTWNEIIPSKGCLRVGGRCHPHVNGVFFNGIILGPDGNVLIPEMQSSLLQQHMELLVSSVIPLMHPLADPSTVFKNGDEAEDFVEVHLPDVHERISGVD,433,"Aditham et al., 2025",Bloom lab (dms-vep),journal,,RABV_G,cell_entry
SARS2_KP311_cell_entry,SARS2_KP311_cell_entry.csv,SARS-CoV-2,Spike KP.3.1.1,cell entry,MFVFLVLLPLVSSQCVMPLFNLITTTQSYTNFTRGVYYPDKVFRSSVLHLTQDLFLPFFSNVTWFHAISGTNGTKRFDNPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIVNNATNVFIKVCEFQFCNDPFLDVYHKNNKSWMESESGVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPIIGRDFPQGFSALEPLVDLPIGINITRFQTLLALNRSYLTPGDSSSGWTAGAADYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNVTNLCPFHEVFNATRFASVYAWNRTRISNCVADYSVLYNFAPFFAFKCYGVSPTKLNDLCFTNVYADSFVIKGNEVSQIAPGQTGNIADYNYKLPDDFTGCVIAWNSNKLDSKHSGNYDYWYRSLRKSKLKPFERDISTEIYQAGNKPCKGKGPNCYFPLESYGFRPTYGVGHQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTKSNKKFLPFQQFGRDIVDTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQGVNCTEVSVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEYVNNSYECDIPIGAGICASYQTQTKSRRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLKRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKYFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLFSTASALGKLQDVVNHNAQALNTLVKQLSSKFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFLTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQLELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKWPWYIWLGFIAGLIAIVMVTIMLCCMTSCCSCLKGCCSCGS,1247,"Dadonaite et al., 2025b",Bloom lab (dms-vep),preprint,"REBUILT 2026-08-27 on true KP.3.1.1 sequence (1247 aa incl MPLF/16a-d insertion); previous build lacked the insertion (1243 aa, +4 shift after site 16) - AF2/MSA and any scores for this assay must be re-run",SARS2_SPIKE,cell_entry
RABV_G_Aditham_escape,RABV_G_Aditham_escape.csv,Rabies virus,G,immune escape,FGKFPIYTIPDKLGPWSPIDIHHLSCPNNLVVEDEGCTNLSGFSYMELKVGYISAIKMNGFTCTGVVTEAETYTNFVGYVTTTFKRKHFRPTPDACRAAYNWKMAGDPRYEESLHNPYPDYHWLRTVKTTKESLVIISPSVADLDPYDRSLHSRVFPGGNCSGVAVSSTYCSTNHDYTIWMPENPRLGMSCDIFTNSRGKRASKGSETCGFVDERGLYKSLKGACKLKLCGVLGLRLMDGTWVAMQTSNETKWCPPGQLVNLHDFRSDEIEHLVVEELVKKREECLDALESIMTTKSVSFRRLSHLRKLVPGFGKAYTIFNKTLMEADAHYKSVRTWNEIIPSKGCLRVGGRCHPHVNGVFFNGIILGPDGNVLIPEMQSSLLQQHMELLVSSVIPLMHPLADPSTVFKNGDEAEDFVEVHLPDVHERISGVD,433,"Aditham et al., 2025",Bloom lab (dms-vep),journal,,RABV_G,immune_escape
SARS2_XBB15_spike_Dadonaite_escape,SARS2_XBB15_spike_Dadonaite_escape.csv,SARS-CoV-2,Spike XBB.1.5,immune escape,FVFLVLLPLVSSQCVNLITRTQSYTNSFTRGVYYPKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFDNPALPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQLLIVNNATNVVIKVCEFQFCNDPFLDVYQKNNKSWMESEFRVYSSANNTFEYVSQPFLMDLEGKEGNFKNLREFVFKNIDGYFKIYSKHTPINLERDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPVDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLETKTLKSFTVEKGIYQTSNFRVQPTESIVFPNITNLPFHEVFNATTFASVYAWNRKRISNVADYSVIYNFAPFFAFKYGVSPTKLNDLFTNVYASFVIRGNEVSQIAGQTGNIADYYKLPDDFTVIAWSNKLSKPSGNYNYLYRLFRKSKLKPFERISTEIYQAGNKPNGVAGPNCYFPLQSYGRPTYVGHYVVLSFELLHAPATPKKSNVKNKVNFLTTVLTENKLPQFGRDIADTTDAVRQTLELDITSFGGSVITNTSNQVVLYQGVNTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGIAEYVNNSYEGAICASYQTQTKSHRRARSVASQSIIATMLAENSVASNNSIAIPTNFTSVTTPSMTKTSVDCTMIGDSTESNLLLQGSFTQLKRATGIAVEKNTQEFAQVKQIYKTPPIKYFGGNFSQILPDPSKPSKRFDLLFNKVTLADAGFIKQYGDLGDIAARDLIAQKFNLTVLPLTDEMIAQYTSALLATITSGWTFGAAAQIAMMYRFNGIGVTQVLEQKLANQFSAGKIQDSLSSTASALGKLQDVVNHNAQANTVKQSSKGSVNDLSRLDKVEAEVIRITGRLQSLQTYVTQQLIRAAEIRASANLAATMSELSKVDFCGKGYLMFSAPHGVVFLVTYVPAQEKNFTTAPAIHDGKAHFPREGVFVSNGTHWFVQRNFYEPQIITTDNTFVSGNDVVIGIVNNTVYDPLQPELDSFKEEDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNNESLIDLQELGKYEQYIPWYIWLGFIAGLIAIVMVTIMLCCMTSCCSCLKGCCSCGS,1115,"Dadonaite et al., 2024b",Bloom lab (dms-vep),journal,,SARS2_SPIKE,immune_escape
SARS2_XBB15_spike_Dadonaite_binding,SARS2_XBB15_spike_Dadonaite_binding.csv,SARS-CoV-2,Spike XBB.1.5,binding,FVFLVLLPLVSSQCVNLITRTQSYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFDNPALPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQLLIVNNATNVVIKVCEFQFCNDPFLDVYQKNNKSWMESEFRVYSSANNTFEYVSQPFLMDLEGKEGNFKNLREFVFKNIDGYFKIYSKHTPINLERDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPVDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVCALDPLSETKTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLPFHEVFNATTFASVYAWNRKRISNVADYSVIYNFAPFFAFKYGVSPTKLNDLFTNVYADSFVIRGNEVSQIAGQTGNIADYYKLPDDFTVIAWSNKLDSKPSGNYNYLYRLFRKSKLKPFERISTEIYQAGNKPNGVAGPNCYFPLQSYGRPTYVGHYVVVLSFELLHAPATGPKKSNLVKNKVNFLTGTVLTENKLPQFGRDIADTTDAVRQTLEILDITPSFGGSVITPNTSNQVAVLYQGVNTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGIAEYVNNSYEIIGAGIASYQTQTKSHRRARSVASQSIIATMLGAENSVASNNSIAIPTNTSVTTLPSMTKTSVDCTMIGDSTESNLLLQYGSFTQLKRALTGIAVEKNTQEFAQVKQIYKTPPIKYFGGFNFSQILPDPSKPSKRFDLLFNKVTLADAGFIKQYGDLGDIAARDLIAQKFNGLTVLPLLTDEMIAQYTSALLATITSGWTFGAAALQIPAMMYFNGIGVTQVLEQKLANQFSAGKIQDSLSSTASALGKLQDVVNHNAQANTVKQSSKGISVLNDILSRLDKVEAEVQIDRITGRLQSLQTYVTQQLIRAAEIRASANLAATMSECVLSKRVDFCGKGYLMSFQSAPHGVVFLHVTYVPAQEKNFTTAPAIHDGKAHFPREGVFVSNGTHWFVQRNFYEPQIITTDNTFVSGNDVVIGIVNNTVYDPLQPELDSFKEEDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIWPWYIWLGFIAGLIAIVMVTIMLCCMTSCCSCLKGCCSCGS,1149,"Dadonaite et al., 2024b",Bloom lab (dms-vep),journal,,SARS2_SPIKE,binding
IAV_H3_HK19_Welsh_viral_growth,IAV_H3_HK19_Welsh_viral_growth.csv,Influenza A H3N2,HA,viral growth,MKALVLLAVATDADTQKIPGNDNSTATLCLGHHAVPNGTIVKTITNDRIEVTNATELVQNSSIGEICDSPHQILDGGNCTLIDALLGDPQCDGFQNKKWDLFVERSRAYSNCYPYDVPDYASLRSLVASSGTLEFKNESFNWAGVTQNGKSFSCIRGSSSSFFSRLNWLTHLNYTYPALNVTMPNKEQFDKLYIWGVHHPGTDKDQISLYAQSSGRITVSTKRSQQAVIPNIGSRPRIRDIPSRISYWTIVKPGDILLINSTGLIAPRGYFKIRSGKSSIMRSDAPIGKCKSECITPNGSIPNDKPFQNVNRITYGACPRYVKQNTLKLATGMRNVPEKQTRGIFGAIAGFIENGWEGMVDGWYGFRHQNSEGRGQAADLKSTQAAIDQINGKLNRLIGKTNEKFHQIEKEFSEVEGRVQDLEKYVEDTKIDLWSYNAELLVALENQHTIDLTDSEMNKLFEKTKKQLRENAEDMGNGCFKIYHKCDNACIGSIRNETYDHNVYRDEALNNRFQIKGVELKSGYKDWILWISFAISCFLLCVALLGFIMWACQK,554,"Welsh et al., 2024",Bloom lab (dms-vep),journal,,IAV_H3_HA,fitness
IAV_H3_HK19_Welsh_escape,IAV_H3_HK19_Welsh_escape.csv,Influenza A H3N2,HA,immune escape,DQKIPGNDNSTATLLGHHAVPNTIVKTITNDRIETNATEQNSSIGEIDSHQILGNIALDQDGFQNKKWLFVSRAYNDVPDYASRSVASSTKNSNATQNKSFSIRGSSSRTHLNYTALNVTMPKEQFDIVHGTDKDISAQSSGRITSKRSQAVIPNIGSRPRIRDIPSRISYWIKILNSLFKIRSGKSSIMRSAPGKKSEITPIPNDKNVNRITYARYVKQNTLKTMVPEKQTRGIFGAIAINEGMVWFRQSERQAADLKSQAAIDQINGKLNRLIGKTNEKFHQKEFSEVEGRVQDLEKYVEDTKIDLYAELLVALQHIDLTDSEMNKFEKTKKQREDMFKIYKNAIGSREDHNVYDELNNFQIKGVLGDWLWFASCFLVALGMWAQ,387,"Welsh et al., 2024",Bloom lab (dms-vep),journal,,IAV_H3_HA,immune_escape
IAV_H3_MC22_Yu_escape,IAV_H3_MC22_Yu_escape.csv,Influenza A H3N2,HA,immune escape,QKIPGNDNSTATLCLGHHAVPNGTIVKTITNDRIEVTNATELVQNSSIGKICNSPHQILDGGNCTLIDALLGDPQCDGFQNKEWDLFVERSRANSSCYPYDVPDYASLRSLVASSGTLEFKNESFNWTGVKQNGTSSACKRGSSSSFFSRLNWLTSLNNIYPAQNVTMPNKEQFDKLYIWGVHHPDTDKNQFSLFAQSSGRITVSTKRSQQAVIPNIGSRPRVRDIPSRISIYWTIVKPGDILLINSTGNLIAPRGYFKIRSGKSSIMRSDAPIGKCKSECITPNGSIPNDKPFQNVNRITYGACPRYVKQSTLKLATGMRNVPEKQTRGIFGAIAGFIENGWEGMVDGWYGFRHQNSEGRGQAADLKSTQAAIDQISGKLNRLIGKTNEKFHQIEKEFSEVEGRVQDLEKYVEDTKIDLWSYNAELLVALENQHTIDLTDSEMNKLFEKTKKQLRENAEDMGNGCFKIYHKCDNACIGSIRNETYDHNVYRDEALNNRFQIKG,504,"Yu et al., 2025",Bloom lab (dms-vep),preprint,,IAV_H3_HA,immune_escape
HBV_RT_Yu_fitness,HBV_RT_Yu_fitness.csv,Hepatitis B virus,RT,fitness,MPLSYQHFRKLLLLDDEAGPLEEELPRLADADLNRRVAEDLNLGNLNVSIPWTHKVGNFTGLYSSTVPIFNPEWQTPSFPKIHLQEDIINRCQQFVGPLTVNEKRRLKLIMPARFYPTHTKYLPLDKGIKPYYPDQVVNHYFQTRHYLHTLWKAGILYKRETTRSASFCGSPYSWEQELQHGRLVIKTSQRHGDESFCSQPSGILSRSSVGPCIRSQLKQSRLGLQPHQGPLASSQPGRSGSIRARAHPSTRRYFGVEPSGSGHIDHSVNNSSSCLHQSAVRKAAYSHLSTSKRQSSSGHAVEFHCLPPSSAGSQSQGSVSSCWWLQFRNSKPCSEYCLSHLVNLREDWGPCDEHGEHHIRIPRTPARVTGGVFLVDKNPHNTAESRLVVDFSQFSRGISRVSWPKFAVPNLQSLTNLLSSNLSWLSLDVSAAFYHIPLHPAAMPHLLIGSSGLSRYVARLSSNSRINNNQYGTMQNLHDSCSRQLYVSLMLLYKTYGWKLHLYSHPIVLGFRKIPMGVGLSPFLLAQFTSAICSVVRRAFPHCLAFSYMDDVVLGAKSVQHRESLYTAVTNFLLSLGIHLNPNKTKRWGYSLNFMGYIIGSWGTLPQDHIVQKIKHCFRKLPVNRPIDWKVCQRIVGLLGFAAPFTQCGYPALMPLYACIQAKQAFTFSPTYKAFLSKQYMNLYPVARQRPGLCQVFADATPTGWGLAIGHQRMRGTFVAPLPIHTAELLAACFARSRSGAKLIGTDNSVVLSRKYTSFPWLLGCTANWILRGTSFVYVPSALNPADDPSRGRLGLSRPLLRLPFQPTTGRTSLYAVSPSVPSHLPVRVHFASPLHVAWRPP,843,"Yu et al., 2024",other,journal,,HBV_RT,fitness
SARS2_XBB15_spike_Dadonaite_cell_entry,SARS2_XBB15_spike_Dadonaite_cell_entry.csv,SARS-CoV-2,Spike XBB.1.5,cell entry,MFVFLVLLPLVSSQCVNLITRTQSYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFDNPALPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLDVYQKNNKSWMESEFRVYSSANNCTFEYVSQPFLMDLEGKEGNFKNLREFVFKNIDGYFKIYSKHTPINLERDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPVDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFHEVFNATTFASVYAWNRKRISNCVADYSVIYNFAPFFAFKCYGVSPTKLNDLCFTNVYADSFVIRGNEVSQIAPGQTGNIADYNYKLPDDFTGCVIAWNSNKLDSKPSGNYNYLYRLFRKSKLKPFERDISTEIYQAGNKPCNGVAGPNCYFPLQSYGFRPTYGVGHQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQGVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEYVNNSYECDIPIGAGICASYQTQTKSHRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLKRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKYFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNHNAQALNTLVKQLSSKFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKWPWYIWLGFIAGLIAIVMVTIMLCCMTSCCSCLKGCCSCGS,1248,"Dadonaite et al., 2024b",Bloom lab (dms-vep),journal,,SARS2_SPIKE,cell_entry
RSV_F_Long_Simonich_entry,RSV_F_Long_Simonich_entry.csv,Respiratory syncytial virus A,F,cell entry,QNITEEFYQSTCSAVSKGYLSALRTGWYTSVITIELSNIKENKCNGTDAKVKLINQELDKYKNAVTELQLLMQSTTAANNRARRELPRFMNYTLNNTKKTNVTLSKKRKRRFLGFLLGVGSAIASGIAVSKVLHLEGEVNKIKSALLSTNKAVVSLSNGVSVLTSKVLDLKNYIDKQLLPIVNKQSCRISNIETVIEFQQKNNRLLEITREFSVNAGVTTPVSTYMLTNSELLSLINDMPITNDQKKLMSNNVQIVRQQSYSIMSIIKEEVLAYVVQLPLYGVIDTPCWKLHTSPLCTTNTKEGSNICLTRTDRGWYCDNAGSVSFFPQAETCKVQSNRVFCDTMNSLTLPSEVNLCNVDIFNPKYDCKIMTSKTDVSSSVITSLGAIVSCYGKTKCTASNKNRGIIKTFSNGCDYVSNKGVDTVSVGNTLYYVNKQEGKSLYVKGEPIINFYDPLVFPSDEFDASISQVNEKINQSLAFIRKSDELLHHVNAGKSTTNIMITT,504,"Simonich et al., 2026 (bioRxiv 2026.02.12.705519)",Bloom lab (dms-vep),preprint,,RSV_F,cell_entry
RSV_F_Long_Simonich_escape,RSV_F_Long_Simonich_escape.csv,Respiratory syncytial virus A,F,immune escape,QNITEEFYQSTCSAVSKGYLSALRTGWYTSVITIELSNIKENKCNGTDAKVKLINQELDKYKNAVTELQLLMQSTTAANNRARRELPRFMNYTLNNTKKTNVTLSKKRKRRFLGFLLGVGSAIASGIAVSKVLHLEGEVNKIKSALLSTNKAVVSLSNGVSVLTSKVLDLKNYIDKQLLPIVNKQSCRISNIETVIEFQQKNNRLLEITREFSVNAGVTTPVSTYMLTNSELLSLINDMPITNDQKKLMSNNVQIVRQQSYSIMSIIKEEVLAYVVQLPLYGVIDTPCWKLHTSPLCTTNTKEGSNICLTRTDRGWYCDNAGSVSFFPQAETCKVQSNRVFCDTMNSLTLPSEVNLCNVDIFNPKYDCKIMTSKTDVSSSVITSLGAIVSCYGKTKCTASNKNRGIIKTFSNGCDYVSNKGVDTVSVGNTLYYVNKQEGKSLYVKGEPIINFYDPLVFPSDEFDASISQVNEKINQSLAFIRKSDELLHHVNAGKSTTNIMITT,504,"Simonich et al., 2026 (bioRxiv 2026.02.12.705519)",Bloom lab (dms-vep),preprint,,RSV_F,immune_escape
RSV_F_Long_Simonich_sera_escape,RSV_F_Long_Simonich_sera_escape.csv,Respiratory syncytial virus A,F,immune escape,QNITEEFYQSTCSAVSKGYLSALRTGWYTSVITIELSNIKENKCNGTDAKVKLINQELDKYKNAVTELQLLMQSTTAANNRARRELPRFMNYTLNNTKKTNVTLSKKRKRRFLGFLLGVGSAIASGIAVSKVLHLEGEVNKIKSALLSTNKAVVSLSNGVSVLTSKVLDLKNYIDKQLLPIVNKQSCRISNIETVIEFQQKNNRLLEITREFSVNAGVTTPVSTYMLTNSELLSLINDMPITNDQKKLMSNNVQIVRQQSYSIMSIIKEEVLAYVVQLPLYGVIDTPCWKLHTSPLCTTNTKEGSNICLTRTDRGWYCDNAGSVSFFPQAETCKVQSNRVFCDTMNSLTLPSEVNLCNVDIFNPKYDCKIMTSKTDVSSSVITSLGAIVSCYGKTKCTASNKNRGIIKTFSNGCDYVSNKGVDTVSVGNTLYYVNKQEGKSLYVKGEPIINFYDPLVFPSDEFDASISQVNEKINQSLAFIRKSDELLHHVNAGKSTTNIMITT,504,"Simonich et al., 2026 (bioRxiv 2026.02.12.705519)",Bloom lab (dms-vep),preprint,,RSV_F,immune_escape
CoV229E_spike_Harari_entry,CoV229E_spike_Harari_entry.csv,Human coronavirus 229E,spike,cell entry,TNGLNTSHSVCNGCVGHSENVFAVESGGYIPSDFAFNNWFLLTNTSSVVDGVVRSFQPLLLNCLWSVSGSRFTTGFVYFNGTGRGDCKGFYSNASSDVIRYNINFERNLRRGTILFKTSYGVVVFYCTNNTLVSGDAHIPFGTVLGNFYCFVNTTIGNETTSAFVGALPKTVREFVISRTGHFYINGYRYFTLGNVEAVNFNVTNAETTVCTVALASYADVLVNVSQTAIANIIYCNSVINRLRCDQLSFDVPDGFYSTSPIQSVELPVSIVSLPVYHKHTFIVLYVDFKLQSGVGRCFNCRPAVVNITLANFNETKGPLCVDTSHFTTKFVGANFGRWSASINTGNCPFSFGKVNNFVKFGSVCFSLKDIPGGCAMPIVANLAYLNSYTIGSLYVSWSDGDVITGVPKPVEGVSSFMNVTLNKCTKYNIYDVSGVGVIRISNDTFLNGITYTSTSGNLLGFKDVTNGTIYSITPCNPPDQLVVYQQAVVGAMLSENFTSYGFSNVVEMPKFFYASNGTYNCTDAVLTYSSFGVCADGSIIAVQPRNVSYDSVSAIVTANLSIPSNWTTSVQVEYLQITSTPIVVDCSTYVCNGNVRCVELLKQYTSACKTIEDALRNSAMLESADVSEMLTFDKKAFTLANVSSFGDYNLSSVIPSLPTSGSRVAGRSAIEDILFSKLVTSGLGTVDADYKKCTKGLSIADLACAQYYNGIMVLPGVADAERMAMYTGSLIGGIALGGLTSAASIPFSLAIQSRLNYVALQTDVLQENQKILAASFNKAMTNIVDAFTGVNDAITQTSQALQTVATALNKIQDVVNQQGNSLNHLTSQLRQNFQAISSSIQAIYDRLDIIQADQQVDRLITGRLAALNVFVSHTLTKYTEVRASRQLAQQKVNECVKSQSKRYGFCGNGTHIFSIVNAAPEGLVFLHTVLLPTQYKDVEAWSGLCVDGRNGYVLRQPNLALYKEGNYYRITSRIMFEPRIPTMADFVQIENCNVTFVNISRSELQTIVPEYIDVNKTLQELSYKLPNYTVPDLVVEQYNQTILNLTSEISTLENKSAELNYTVQKLQTLIDNINSTLVDLKWLNRVETYIKWPWWVWLCISVVLIFVVSMLLLCCCST,1119,"Harari et al., 2026 (bioRxiv 2026.02.22.707297)",Bloom lab (dms-vep),preprint,,CoV229E_SPIKE,cell_entry
CoV229E_spike_Harari_binding,CoV229E_spike_Harari_binding.csv,Human coronavirus 229E,spike,binding,TNGLNTSHSVCNGCVGHSENVFAVESGGYIPSDFAFNNWFLLTNTSSVVDGVVRSFQPLLLNCLWSVSGSRFTTGFVYFNGTGRGDCKGFYSNASSDVIRYNINFERNLRRGTILFKTSYGVVVFYCTNNTLVSGDAHIPFGTVLGNFYCFVNTTIGNETTSAFVGALPKTVREFVISRTGHFYINGYRYFTLGNVEAVNFNVTNAETTVCTVALASYADVLVNVSQTAIANIIYCNSVINRLRCDQLSFDVPDGFYSTSPIQSVELPVSIVSLPVYHKHTFIVLYVDFKLQSGVGRCFNCRPAVVNITLANFNETKGPLCVDTSHFTTKFVGANFGRWSASINTGNCPFSFGKVNNFVKFGSVCFSLKDIPGGCAMPIVANLAYLNSYTIGSLYVSWSDGDVITGVPKPVEGVSSFMNVTLNKCTKYNIYDVSGVGVIRISNDTFLNGITYTSTSGNLLGFKDVTNGTIYSITPCNPPDQLVVYQQAVVGAMLSENFTSYGFSNVVEMPKFFYASNGTYNCTDAVLTYSSFGVCADGSIIAVQPRNVSYDSVSAIVTANLSIPSNWTTSVQVEYLQITSTPIVVDCSTYVCNGNVRCVELLKQYTSACKTIEDALRNSAMLESADVSEMLTFDKKAFTLANVSSFGDYNLSSVIPSLPTSGSRVAGRSAIEDILFSKLVTSGLGTVDADYKKCTKGLSIADLACAQYYNGIMVLPGVADAERMAMYTGSLIGGIALGGLTSAASIPFSLAIQSRLNYVALQTDVLQENQKILAASFNKAMTNIVDAFTGVNDAITQTSQALQTVATALNKIQDVVNQQGNSLNHLTSQLRQNFQAISSSIQAIYDRLDIIQADQQVDRLITGRLAALNVFVSHTLTKYTEVRASRQLAQQKVNECVKSQSKRYGFCGNGTHIFSIVNAAPEGLVFLHTVLLPTQYKDVEAWSGLCVDGRNGYVLRQPNLALYKEGNYYRITSRIMFEPRIPTMADFVQIENCNVTFVNISRSELQTIVPEYIDVNKTLQELSYKLPNYTVPDLVVEQYNQTILNLTSEISTLENKSAELNYTVQKLQTLIDNINSTLVDLKWLNRVETYIKWPWWVWLCISVVLIFVVSMLLLCCCST,1119,"Harari et al., 2026 (bioRxiv 2026.02.22.707297)",Bloom lab (dms-vep),preprint,,CoV229E_SPIKE,binding
CoV229E_spike_Harari_sera_escape,CoV229E_spike_Harari_sera_escape.csv,Human coronavirus 229E,spike,immune escape,TNGLNTSHSVCNGCVGHSENVFAVESGGYIPSDFAFNNWFLLTNTSSVVDGVVRSFQPLLLNCLWSVSGSRFTTGFVYFNGTGRGDCKGFYSNASSDVIRYNINFERNLRRGTILFKTSYGVVVFYCTNNTLVSGDAHIPFGTVLGNFYCFVNTTIGNETTSAFVGALPKTVREFVISRTGHFYINGYRYFTLGNVEAVNFNVTNAETTVCTVALASYADVLVNVSQTAIANIIYCNSVINRLRCDQLSFDVPDGFYSTSPIQSVELPVSIVSLPVYHKHTFIVLYVDFKLQSGVGRCFNCRPAVVNITLANFNETKGPLCVDTSHFTTKFVGANFGRWSASINTGNCPFSFGKVNNFVKFGSVCFSLKDIPGGCAMPIVANLAYLNSYTIGSLYVSWSDGDVITGVPKPVEGVSSFMNVTLNKCTKYNIYDVSGVGVIRISNDTFLNGITYTSTSGNLLGFKDVTNGTIYSITPCNPPDQLVVYQQAVVGAMLSENFTSYGFSNVVEMPKFFYASNGTYNCTDAVLTYSSFGVCADGSIIAVQPRNVSYDSVSAIVTANLSIPSNWTTSVQVEYLQITSTPIVVDCSTYVCNGNVRCVELLKQYTSACKTIEDALRNSAMLESADVSEMLTFDKKAFTLANVSSFGDYNLSSVIPSLPTSGSRVAGRSAIEDILFSKLVTSGLGTVDADYKKCTKGLSIADLACAQYYNGIMVLPGVADAERMAMYTGSLIGGIALGGLTSAASIPFSLAIQSRLNYVALQTDVLQENQKILAASFNKAMTNIVDAFTGVNDAITQTSQALQTVATALNKIQDVVNQQGNSLNHLTSQLRQNFQAISSSIQAIYDRLDIIQADQQVDRLITGRLAALNVFVSHTLTKYTEVRASRQLAQQKVNECVKSQSKRYGFCGNGTHIFSIVNAAPEGLVFLHTVLLPTQYKDVEAWSGLCVDGRNGYVLRQPNLALYKEGNYYRITSRIMFEPRIPTMADFVQIENCNVTFVNISRSELQTIVPEYIDVNKTLQELSYKLPNYTVPDLVVEQYNQTILNLTSEISTLENKSAELNYTVQKLQTLIDNINSTLVDLKWLNRVETYIKWPWWVWLCISVVLIFVVSMLLLCCCST,1119,"Harari et al., 2026 (bioRxiv 2026.02.22.707297)",Bloom lab (dms-vep),preprint,,CoV229E_SPIKE,immune_escape
IAV_H7_Anhui13_Ahn_entry_sa23,IAV_H7_Anhui13_Ahn_entry_sa23.csv,Influenza A H7N9,HA,cell entry,DKICLGHHAVSNGTKVNTLTERGVEVVNATETVERTNIPRICSKGKRTVDLGQCGLLGTITGPPQCDQFLEFSADLIIERREGSDVCYPGKFVNEEALRQILRESGGIDKEAMGFTYSGIRTNGATSACRRSGSSFYAEMKWLLSNTDNAAFPQMTKSYKNTRKSPALIVWGIHHSVSTAEQTKLYGSGNKLVTVGSSNYQQSFVPSPGARPQVNGLSGRIDFHWLMLNPNDTVTFSFNGAFIAPDRASFLRGKSMGIQSGVQVDANCEGDCYHSGGTIISNLPFQNIDSRAVGKCPRYVKQRSLLLATGMKNVPEIPKGRGLFGAIAGFIENGWEGLIDGWYGFRHQNAQGEGTAADYKSTQSAIDQITGKLNRLIEKTNQQFELIDNEFNEVEKQIGNVINWTRDSITEVWSYNAELLVAMENQHTIDLADSEMDKLYERVKRQLRENAEEDGTGCFEIFHKCDDDCMASIRNNTYDHSKYREEAMQNRIQIDPVKLSSGYKDV,506,"Yu et al., 2026 (Virus Evolution 12:veag018)",Bloom lab (dms-vep),journal,,IAV_H7_HA,cell_entry
IAV_H7_Anhui13_Ahn_entry_sa26,IAV_H7_Anhui13_Ahn_entry_sa26.csv,Influenza A H7N9,HA,cell entry,DKICLGHHAVSNGTKVNTLTERGVEVVNATETVERTNIPRICSKGKRTVDLGQCGLLGTITGPPQCDQFLEFSADLIIERREGSDVCYPGKFVNEEALRQILRESGGIDKEAMGFTYSGIRTNGATSACRRSGSSFYAEMKWLLSNTDNAAFPQMTKSYKNTRKSPALIVWGIHHSVSTAEQTKLYGSGNKLVTVGSSNYQQSFVPSPGARPQVNGLSGRIDFHWLMLNPNDTVTFSFNGAFIAPDRASFLRGKSMGIQSGVQVDANCEGDCYHSGGTIISNLPFQNIDSRAVGKCPRYVKQRSLLLATGMKNVPEIPKGRGLFGAIAGFIENGWEGLIDGWYGFRHQNAQGEGTAADYKSTQSAIDQITGKLNRLIEKTNQQFELIDNEFNEVEKQIGNVINWTRDSITEVWSYNAELLVAMENQHTIDLADSEMDKLYERVKRQLRENAEEDGTGCFEIFHKCDDDCMASIRNNTYDHSKYREEAMQNRIQIDPVKLSSGYKDV,506,"Yu et al., 2026 (Virus Evolution 12:veag018)",Bloom lab (dms-vep),journal,,IAV_H7_HA,cell_entry
CHIKV_E_Ju_entry_human,CHIKV_E_Ju_entry_human.csv,Chikungunya virus,E3/E2/E1,cell entry,MSLAIPVMCLLANTTFPCSQPPCTPCCYEKEPEKTLRMLEDNVMSPGYYQLLQASLTCSPRRQRRSIKDNFNVYKAIRPYLAHCPDCGEGHSCHSPVALERIRNEATDGTLKIQVSLQIGIKTDDSHDWTKLRYMDNHMPADAERARLFVRTSAPCTITGTMGHFILARCPKGETLTVGFTDGRKISHSCTHPFHHDPPVIGREKFHSRPQHGRELPCSTYAQSTAATAEEIEVHMPPDTPDRTLMSQQSGNVKITVNSQTVRYKCNCGDSNEGLTTTDKVINNCKVDQCHAAVTNHKKWQYNSPLVPRNAELGDRKGKVHIPFPLANVTCRVPKARNPTVTYGKNQVIMLLYPDHPTLLSYRNMGEEPNYQEEWVTHKKEIRLTVPTEGLEVTWGNNEPYKYWPQLSTNGTAHGHPHEIILYYYELYPTMTVVVVSVASFVLLSMVGVAVGMCMCARRRCITPYELTPGATVPFLLSLICCIRTAKAATYQEAAVYLWNEQQPLFWLQALIPLAALIVLCNCLRLLPCFCKTLTFLAVMSVGAHTVSAYEHVTVIPNTVGVPYKTLVNRPGYSPMVLEMELLSVTLEPTLSLDYITCEYKTVIPSPYVKCCGTAECKDKSLPDYSCKVFTGVYPFMWGGAYCFCDTENTQLSEAHVEKSESCKTEFASAYRAHTASASAKLRVLYQGNNVTVSAYANGDHAVTVKDAKFIVGPMSSAWTPFDNKIVVYKGDVYNMDYPPFGAGRPGQFGDIQSRTPESEDVYANTQLVLQRPSAGTVHVPYSQAPSGFKYWLKERGASLQHTAPFGCQIATNPVRAMNCAVGNMPISIDIPDAAFTRVVDAPSLTDMSCEVPACTHSSDFGGVAIIKYAASKKGKCAVHSMTNAVTIREAEIEVEGNSQLQISFSTALASAEFRVQVCSTQVHCAAECHPPKDHIVNYPASHTTLGVQDISVTAMSWVQKITGGVGLVVAVAALILIVVLCVSFSRH,988,"Ju et al., 2025 (bioRxiv 2025.08.25.672233)",Bloom lab (dms-vep),preprint,,CHIKV_E,cell_entry
CHIKV_E_Ju_entry_mosquito,CHIKV_E_Ju_entry_mosquito.csv,Chikungunya virus,E3/E2/E1,cell entry,MSLAIPVMCLLANTTFPCSQPPCTPCCYEKEPEKTLRMLEDNVMSPGYYQLLQASLTCSPRRQRRSIKDNFNVYKAIRPYLAHCPDCGEGHSCHSPVALERIRNEATDGTLKIQVSLQIGIKTDDSHDWTKLRYMDNHMPADAERARLFVRTSAPCTITGTMGHFILARCPKGETLTVGFTDGRKISHSCTHPFHHDPPVIGREKFHSRPQHGRELPCSTYAQSTAATAEEIEVHMPPDTPDRTLMSQQSGNVKITVNSQTVRYKCNCGDSNEGLTTTDKVINNCKVDQCHAAVTNHKKWQYNSPLVPRNAELGDRKGKVHIPFPLANVTCRVPKARNPTVTYGKNQVIMLLYPDHPTLLSYRNMGEEPNYQEEWVTHKKEIRLTVPTEGLEVTWGNNEPYKYWPQLSTNGTAHGHPHEIILYYYELYPTMTVVVVSVASFVLLSMVGVAVGMCMCARRRCITPYELTPGATVPFLLSLICCIRTAKAATYQEAAVYLWNEQQPLFWLQALIPLAALIVLCNCLRLLPCFCKTLTFLAVMSVGAHTVSAYEHVTVIPNTVGVPYKTLVNRPGYSPMVLEMELLSVTLEPTLSLDYITCEYKTVIPSPYVKCCGTAECKDKSLPDYSCKVFTGVYPFMWGGAYCFCDTENTQLSEAHVEKSESCKTEFASAYRAHTASASAKLRVLYQGNNVTVSAYANGDHAVTVKDAKFIVGPMSSAWTPFDNKIVVYKGDVYNMDYPPFGAGRPGQFGDIQSRTPESEDVYANTQLVLQRPSAGTVHVPYSQAPSGFKYWLKERGASLQHTAPFGCQIATNPVRAMNCAVGNMPISIDIPDAAFTRVVDAPSLTDMSCEVPACTHSSDFGGVAIIKYAASKKGKCAVHSMTNAVTIREAEIEVEGNSQLQISFSTALASAEFRVQVCSTQVHCAAECHPPKDHIVNYPASHTTLGVQDISVTAMSWVQKITGGVGLVVAVAALILIVVLCVSFSRH,988,"Ju et al., 2025 (bioRxiv 2025.08.25.672233)",Bloom lab (dms-vep),preprint,,CHIKV_E,cell_entry
CHIKV_E_Ju_binding,CHIKV_E_Ju_binding.csv,Chikungunya virus,E3/E2/E1,binding,MSLAIPVMCLLANTTFPCSQPPCTPCCYEKEPEKTLRMLEDNVMSPGYYQLLQASLTCSPRRQRRSIKDNFNVYKAIRPYLAHCPDCGEGHSCHSPVALERIRNEATDGTLKIQVSLQIGIKTDDSHDWTKLRYMDNHMPADAERARLFVRTSAPCTITGTMGHFILARCPKGETLTVGFTDGRKISHSCTHPFHHDPPVIGREKFHSRPQHGRELPCSTYAQSTAATAEEIEVHMPPDTPDRTLMSQQSGNVKITVNSQTVRYKCNCGDSNEGLTTTDKVINNCKVDQCHAAVTNHKKWQYNSPLVPRNAELGDRKGKVHIPFPLANVTCRVPKARNPTVTYGKNQVIMLLYPDHPTLLSYRNMGEEPNYQEEWVTHKKEIRLTVPTEGLEVTWGNNEPYKYWPQLSTNGTAHGHPHEIILYYYELYPTMTVVVVSVASFVLLSMVGVAVGMCMCARRRCITPYELTPGATVPFLLSLICCIRTAKAATYQEAAVYLWNEQQPLFWLQALIPLAALIVLCNCLRLLPCFCKTLTFLAVMSVGAHTVSAYEHVTVIPNTVGVPYKTLVNRPGYSPMVLEMELLSVTLEPTLSLDYITCEYKTVIPSPYVKCCGTAECKDKSLPDYSCKVFTGVYPFMWGGAYCFCDTENTQLSEAHVEKSESCKTEFASAYRAHTASASAKLRVLYQGNNVTVSAYANGDHAVTVKDAKFIVGPMSSAWTPFDNKIVVYKGDVYNMDYPPFGAGRPGQFGDIQSRTPESEDVYANTQLVLQRPSAGTVHVPYSQAPSGFKYWLKERGASLQHTAPFGCQIATNPVRAMNCAVGNMPISIDIPDAAFTRVVDAPSLTDMSCEVPACTHSSDFGGVAIIKYAASKKGKCAVHSMTNAVTIREAEIEVEGNSQLQISFSTALASAEFRVQVCSTQVHCAAECHPPKDHIVNYPASHTTLGVQDISVTAMSWVQKITGGVGLVVAVAALILIVVLCVSFSRH,988,"Ju et al., 2025 (bioRxiv 2025.08.25.672233)",Bloom lab (dms-vep),preprint,,CHIKV_E,binding
HIV_BF520_Env_Radford_mAb_escape,HIV_BF520_Env_Radford_mAb_escape.csv,HIV-1,Env BF520,immune escape,MRVKGIQMNSQHLLRWGIMILGMIMICSVAGNLWVTVYYGVPVWKDAETTLFCASDAKAYDAEVHNIWATHACVPTDPNPQEINLENVTEEFNMWKNNMVEQMHTDIISLWDQGLKPCVKLTPLCVTLDCHNVTYNITSDMKEEITNCSYNVTTVIRDKKQKVSSLFYKLDVVQIGGNNRTNSQYRLINCNTSAITQACPKVTFEPIPIHYCAPAGFAILKCKDEKFNGTGLCKNVSTVQCTHGIKPVVSTQLLLNGSLAEGEVRIRSENITNNAKNIIVQLASPVTINCIRPNNNTRKSVHLGPGQAFYATDGIIGEIRQAHCNVSKKEWNSTLQKVANQLRPYFKNNTIIKFANSSGGDLEITTHSFNCGGEFFYCNTSGLFNSTWEFNSTWNNSNSTENITLQCRIKQIINMWQRAGQAIYAPPIPGVIRCKSNITGLILTRDGGSNKNTSETFRPGGGDMRDNWRSELYKYKVVKIEPIGVAPTRAKRRVVEREKRAVGIGAVFIGFLGAAGSTMGAASVTLTVQARQLLSGIVQQQSNLLRAIEAQQHLLKLTVWGIKQLQARVLAVERYLKDQQLLGIWGCSGKLICTTNVPWNSSWSNKSQDEIWGNMTWLQWDKEVSNYTQIIYTLIEESQNQQEKNEQDLLALDKWASLWNWFNISQWLWYIKIFIIIVGGLIGLRIVFAVLSVINRVRQGYSPLSFQTRTPNPGELDRPGRIEEEGGEQDRGRSIRLVSGFLALAWDDLRSLCLFSYHRLRDFILIATRTVELLGHSSLKGLRLGWESLKYLGNLLVYWGRELKISAINLCDTIAIAVAGWTDRVIELGQRLCRAILHIPRRIRQGFERALL,852,"Radford et al., 2023; Radford & Bloom, 2025",Bloom lab (dms-vep),preprint,"(mean of >=2/5 mAb maps: 3BNC117 x2 studies, 1-18, PGT151, 10-1074)",HIV_ENV,immune_escape
HIV_BF520_Env_Radford_sera_escape,HIV_BF520_Env_Radford_sera_escape.csv,HIV-1,Env BF520,immune escape,MRVKGIQMNSQHLLRWGIMILGMIMICSVAGNLWVTVYYGVPVWKDAETTLFCASDAKAYDAEVHNIWATHACVPTDPNPQEINLENVTEEFNMWKNNMVEQMHTDIISLWDQGLKPCVKLTPLCVTLDCHNVTYNITSDMKEEITNCSYNVTTVIRDKKQKVSSLFYKLDVVQIGGNNRTNSQYRLINCNTSAITQACPKVTFEPIPIHYCAPAGFAILKCKDEKFNGTGLCKNVSTVQCTHGIKPVVSTQLLLNGSLAEGEVRIRSENITNNAKNIIVQLASPVTINCIRPNNNTRKSVHLGPGQAFYATDGIIGEIRQAHCNVSKKEWNSTLQKVANQLRPYFKNNTIIKFANSSGGDLEITTHSFNCGGEFFYCNTSGLFNSTWEFNSTWNNSNSTENITLQCRIKQIINMWQRAGQAIYAPPIPGVIRCKSNITGLILTRDGGSNKNTSETFRPGGGDMRDNWRSELYKYKVVKIEPIGVAPTRAKRRVVEREKRAVGIGAVFIGFLGAAGSTMGAASVTLTVQARQLLSGIVQQQSNLLRAIEAQQHLLKLTVWGIKQLQARVLAVERYLKDQQLLGIWGCSGKLICTTNVPWNSSWSNKSQDEIWGNMTWLQWDKEVSNYTQIIYTLIEESQNQQEKNEQDLLALDKWASLWNWFNISQWLWYIKIFIIIVGGLIGLRIVFAVLSVINRVRQGYSPLSFQTRTPNPGELDRPGRIEEEGGEQDRGRSIRLVSGFLALAWDDLRSLCLFSYHRLRDFILIATRTVELLGHSSLKGLRLGWESLKYLGNLLVYWGRELKISAINLCDTIAIAVAGWTDRVIELGQRLCRAILHIPRRIRQGFERALL,852,"Radford et al., 2023",Bloom lab (dms-vep),journal,(mean of >=2/4 human sera),HIV_ENV,immune_escape
HIV_TRO11_Env_Radford_mAb_escape,HIV_TRO11_Env_Radford_mAb_escape.csv,HIV-1,Env TRO11,immune escape,MRAKGIRKNCQHLWIWGTMLLGMLMIYSAAEQGQLWVTVYYGVPVWKDASTTLFCASDAKAYDTEVHNVWATHACVPTDPNPQEVVLGNVTENFNMWKNNMVDQMHEDIISLWDQSLKPCVKLTPLCVTLNCTDNITNTNTNSSKNSSTHSYNNSLEGEMKNCSFNITAGIRDKVKKEYALFYKLDVVPIEEDKDTNKTTYRLRSCNTSVITQACPKVTFEPIPIHYCAPAGFAILKCNDKKFNGTGPCTNVSTVQCTHGIRPVVSTQLLLNGSLAEEEVVIRSENFTNNAKTIIVQLNESIAINCTRPNNNTRRSIHIGPGRAFYATGDIIGDIRQAHCNISRTEWNSTLRQIVTKLREQLGDPNKTIIFNQSSGGDTEITMHSFNCGGEFFYCNTTKLFNSTWNGNNTTESDSTGENITLPCRIKQIINLWQEVGKAMYAPPIKGQISCSSNITGLLLTRDGGNNNSSGPETFRPGGGNMKDNWRSELYKYKVIKIEPLGVAPTRAKRRVVQREKRAVGTLGAMFLGFLGAAGSTMGAASVTLTVQARLLLSGIVQQQNNLLRAIEAQQHMLQLTVWGIKQLQARVLAVERYLRDQQLLGIWGCSGKLICTTNVPWNASWSNKSLNNIWENMTWMEWEREIDNYTDLIYILLEKSQIQQEKNEQELLELDSWASLWNWFDISKWLWYIKIFIMIVGGLVGLRIVFAVLSIANRVRQGYSPLSFQTRLPTPRGPDRPEGIEKEGGGRDRDGSRPLVHGLLALIWDDLRSLCLFSYHRLRDLLLIVTRTVELLGRRGWELLKYWWNLLQYWSQELKNSAVSLLNTTAIAVAEGTDRVIEVVQRAFRAILHIPARIRQGLERALL,864,"Radford & Bloom, 2025",Bloom lab (dms-vep),preprint,(mean of 3BNC117 + 10-1074),HIV_ENV,immune_escape
IAV_H3_MC22_Yu_stability,IAV_H3_MC22_Yu_stability.csv,Influenza A H3N2,HA,stability,QKIPGNDNSTATLCLGHHAVPNGTIVKTITNDRIEVTNATELVQNSSIGKICNSPHQILDGGNCTLIDALLGDPQCDGFQNKEWDLFVERSRANSSCYPYDVPDYASLRSLVASSGTLEFKNESFNWTGVKQNGTSSACKRGSSSSFFSRLNWLTSLNNIYPAQNVTMPNKEQFDKLYIWGVHHPDTDKNQFSLFAQSSGRITVSTKRSQQAVIPNIGSRPRVRDIPSRISIYWTIVKPGDILLINSTGNLIAPRGYFKIRSGKSSIMRSDAPIGKCKSECITPNGSIPNDKPFQNVNRITYGACPRYVKQSTLKLATGMRNVPEKQTRGIFGAIAGFIENGWEGMVDGWYGFRHQNSEGRGQAADLKSTQAAIDQISGKLNRLIGKTNEKFHQIEKEFSEVEGRVQDLEKYVEDTKIDLWSYNAELLVALENQHTIDLTDSEMNKLFEKTKKQLRENAEDMGNGCFKIYHKCDNACIGSIRNETYDHNVYRDEALNNRFQIKG,504,"Yu et al., 2025",Bloom lab (dms-vep),preprint,(pH stability selection),IAV_H3_HA,stability
IAV_H5_HA_Dadonaite_sera_escape,IAV_H5_HA_Dadonaite_sera_escape.csv,Influenza A H5N1,HA,immune escape,MENIVLLLAIVSLVKSDQICIGYHANNSTEQVDTIMEKNVTVTHAQDILEKTHNGKLCDLNGVKPLILKDCSVAGWLLGNPMCDEFIRVPEWSYIVERANPANDLCYPGSLNDYEELKHMLSRINHFEKILIIPKSSWPNHETSLGVSAACPYQGAPSFFRNVVWLIKKNDAYPTIKISYNNTNREDLLILWGIHHSNNAEEQTNLYKNPTTYISVGTSTLNQRLAPKIATRSQVNGQRGRMDFFWTILKPDDAIHFESNGNFIAPEYAYKIVKKGDSTIMKSGVEYGHCNTKCQTPVGAINSSMPFHNIHPLTIGECPKYVKSNKLVLATGLRNSPLREKRRKRGLFGAIAGFIEGGWQGMVDGWYGYHHSNEQGSGYAADKESTQKAIDGVTNKVNSIIDKMNTQFEAVGREFNNLERRIENLNKKMEDGFLDVWTYNAELLVLMENERTLDFHDSNVKNLYDKVRLQLRDNAKELGNGCFEFYHKCDNECMESVRNGTYDYPQYSEEARLKREEISGVKLESVGTYQILSIYSTAASSLALAIMMAGLSLWMCSNGSLQCRICI,567,"Dadonaite et al., 2024a",Bloom lab (dms-vep),journal,(species sera escape),IAV_H5_HA,immune_escape
IAV_H5_HA_Dadonaite_stability,IAV_H5_HA_Dadonaite_stability.csv,Influenza A H5N1,HA,stability,MENIVLLLAIVSLVKSDQICIGYHANNSTEQVDTIMEKNVTVTHAQDILEKTHNGKLCDLNGVKPLILKDCSVAGWLLGNPMCDEFIRVPEWSYIVERANPANDLCYPGSLNDYEELKHMLSRINHFEKILIIPKSSWPNHETSLGVSAACPYQGAPSFFRNVVWLIKKNDAYPTIKISYNNTNREDLLILWGIHHSNNAEEQTNLYKNPTTYISVGTSTLNQRLAPKIATRSQVNGQRGRMDFFWTILKPDDAIHFESNGNFIAPEYAYKIVKKGDSTIMKSGVEYGHCNTKCQTPVGAINSSMPFHNIHPLTIGECPKYVKSNKLVLATGLRNSPLREKRRKRGLFGAIAGFIEGGWQGMVDGWYGYHHSNEQGSGYAADKESTQKAIDGVTNKVNSIIDKMNTQFEAVGREFNNLERRIENLNKKMEDGFLDVWTYNAELLVLMENERTLDFHDSNVKNLYDKVRLQLRDNAKELGNGCFEFYHKCDNECMESVRNGTYDYPQYSEEARLKREEISGVKLESVGTYQILSIYSTAASSLALAIMMAGLSLWMCSNGSLQCRICI,567,"Dadonaite et al., 2024a",Bloom lab (dms-vep),journal,(stability),IAV_H5_HA,stability
LASSA_GP_Carr_mAb_escape,LASSA_GP_Carr_mAb_escape.csv,Lassa virus,GP,immune escape,MGQIVTFFQEVPHVIEEVMNIVLIALSVLAVLKGLYNFATCGLVGLVTFLLLCGRSCTTSLYKGVYELQTLELNMETLNMTMPLSCTKNNSHHYIMVGNETGLELTLTNTSIINHKFCNLSDAHKKNLYDHALMSIISTFHLSIPNFNQYEAMSCDFNGGKISVQYNLSHSYAGDAANHCGTVANGVLQTFMRMAWGGSYIALDSGRGNWDCIMTSYQYLIIQNTTWEDHCQFSRPSPIGYLGLLSQRTRDIYISRRLLGTFTWTLSDSEGKDTPGGYCLTRWMLIEAELKCFGNTAVAKCNEKHDEEFCDMLRLFDFNKQAIQRLKAEAQMSIQLINKAVNALINDQLIMKNHLRDIMGIPYCNYSKYWYLNHTTTGRTSLPKCWLVSNGSYLNETHFSDDIEQQADNMITEMLQKEYMERQGKTPLGLVDLFVFSTSFYLISIFLHLVKIPTHRHIVGKSCPKPHRLNHMGICSCGLYKQPGVPVKWKR,491,"Carr et al., 2024",Bloom lab (dms-vep),preprint,"(mean of >=3/6 mAbs: 121F,2510C,256A,372D,377H,89F)",LASSA_GP,immune_escape
NIPAH_RBP_Larsen_binding,NIPAH_RBP_Larsen_binding.csv,Nipah virus,G (RBP),binding,MPAENKKVRFENTTSDKGKIPSKVIKSYYGTMDIKKINEGLLDSKILSAFNTVIALLGSIVIIVMNIMIIQNYTRSTDNQAVIKDALQGIQQQIKGLADKIGTEIGPKVSLIDTSSTITIPANIGLLGSKISQSTASINENVNEKCKFTLPPLKIHECNISCPNPLPFREYRPQTEGVSNLVGLPNNICLQKTSNQILKPKLISYTLPVVGQSGTCITDPLLAMDEGYFAYSHLERIGSCSRGVSKQRIIGVGEVLDRGDEVPSLFMTNVWTPPNPNTVYHCSAVYNNEFYYVLCAVSTVGDPILNSTYWSGSLMMTRLAVKPKSNGGGYNQHQLALRSIEKGRYDKVMPYGPSGIKQGDTLYFPAVGFLVRTEFKYNDSNCPITKCQYSKPENCRLSMGIRPNSHYILRSGLLKYNLSDGENPKVVFIEISDQRLSIGSPSKIYDSLGQPVFYQASFSWDTMIKFGDVLTVNPLVVNWRNNTVISRPGQSQCPRFNTCPEICWEGVYNDAFLIDRINWISAGVFLDSNQTAENPVFTVFKDNEILYRAQLASEDTNAQKTITNCFLLKNKIWCISLVEIYDTGDNVIRPKLFAVKIPEQCT,602,"Larsen et al., 2025",Bloom lab (dms-vep),preprint,(mean of EphrinB2+B3 monomeric/dimeric binding),NIPAH_RBP,binding
NIPAH_RBP_Larsen_mAb_escape,NIPAH_RBP_Larsen_mAb_escape.csv,Nipah virus,G (RBP),immune escape,MPAENKKVRFENTTSDKGKIPSKVIKSYYGTMDIKKINEGLLDSKILSAFNTVIALLGSIVIIVMNIMIIQNYTRSTDNQAVIKDALQGIQQQIKGLADKIGTEIGPKVSLIDTSSTITIPANIGLLGSKISQSTASINENVNEKCKFTLPPLKIHECNISCPNPLPFREYRPQTEGVSNLVGLPNNICLQKTSNQILKPKLISYTLPVVGQSGTCITDPLLAMDEGYFAYSHLERIGSCSRGVSKQRIIGVGEVLDRGDEVPSLFMTNVWTPPNPNTVYHCSAVYNNEFYYVLCAVSTVGDPILNSTYWSGSLMMTRLAVKPKSNGGGYNQHQLALRSIEKGRYDKVMPYGPSGIKQGDTLYFPAVGFLVRTEFKYNDSNCPITKCQYSKPENCRLSMGIRPNSHYILRSGLLKYNLSDGENPKVVFIEISDQRLSIGSPSKIYDSLGQPVFYQASFSWDTMIKFGDVLTVNPLVVNWRNNTVISRPGQSQCPRFNTCPEICWEGVYNDAFLIDRINWISAGVFLDSNQTAENPVFTVFKDNEILYRAQLASEDTNAQKTITNCFLLKNKIWCISLVEIYDTGDNVIRPKLFAVKIPEQCT,602,"Larsen et al., 2025",Bloom lab (dms-vep),preprint,"(mean over 6 mAbs pre-averaged by source: HENV26/32/103/117, m102.4, nAH1.3)",NIPAH_RBP,immune_escape
SARS2_RBD_Omicron_XBB15_Dadonaite_cell_entry,SARS2_RBD_Omicron_XBB15_Dadonaite_cell_entry.csv,SARS-CoV-2,RBD XBB.1.5,cell entry,NITNLCPFHEVFNATTFASVYAWNRKRISNCVADYSVIYNFAPFFAFKCYGVSPTKLNDLCFTNVYADSFVIRGNEVSQIAPGQTGNIADYNYKLPDDFTGCVIAWNSNKLDSKPSGNYNYLYRLFRKSKLKPFERDISTEIYQAGNKPCNGVAGPNCYSPLQSYGFRPTYGVGHQPYRVVVLSFELLHAPATVCGPKKST,201,"Dadonaite et al., 2025a",Bloom lab (dms-vep),preprint,(spike mediated entry),SARS2_RBD,cell_entry
SARS2_RBD_Omicron_XBB15_Dadonaite_sera_escape,SARS2_RBD_Omicron_XBB15_Dadonaite_sera_escape.csv,SARS-CoV-2,RBD XBB.1.5,immune escape,NITNLCPFHEVFNATTFASVYAWNRKRISNCVADYSVIYNFAPFFAFKCYGVSPTKLNDLCFTNVYADSFVIRGNEVSQIAPGQTGNIADYNYKLPDDFTGCVIAWNSNKLDSKPSGNYNYLYRLFRKSKLKPFERDISTEIYQAGNKPCNGVAGPNCYSPLQSYGFRPTYGVGHQPYRVVVLSFELLHAPATVCGPKKST,201,"Dadonaite et al., 2025a",Bloom lab (dms-vep),preprint,(human sera escape),SARS2_RBD,immune_escape
SARS2_BA2_spike_Dadonaite_binding,SARS2_BA2_spike_Dadonaite_binding.csv,SARS-CoV-2,Spike BA.2,binding,MFVFLVLLPLVSSQCVNLITRTQSYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFDNPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLDVYYHKNNKSWMESEFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINLGRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFDEVFNATRFASVYAWNRKRISNCVADYSVLYNFAPFFAFKCYGVSPTKLNDLCFTNVYADSFVIRGNEVSQIAPGQTGNIADYNYKLPDDFTGCVIAWNSNKLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGNKPCNGVAGFNCYFPLRSYGFRPTYGVGHQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQGVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEYVNNSYECDIPIGAGICASYQTQTKSHRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLKRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKYFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNHNAQALNTLVKQLSSKFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKWPWYIWLGFIAGLIAIVMVTIMLCCMTSCCSCLKGCCSCGSCCKFDEDDSEPVLKGVKLHYT,1270,"Dadonaite et al., 2024",Bloom lab (dms-vep),journal,(ACE2 binding),SARS2_SPIKE,binding
SARS2_BA2_spike_Dadonaite_cell_entry,SARS2_BA2_spike_Dadonaite_cell_entry.csv,SARS-CoV-2,Spike BA.2,cell entry,MFVFLVLLPLVSSQCVNLITRTQSYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFDNPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLDVYYHKNNKSWMESEFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINLGRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFDEVFNATRFASVYAWNRKRISNCVADYSVLYNFAPFFAFKCYGVSPTKLNDLCFTNVYADSFVIRGNEVSQIAPGQTGNIADYNYKLPDDFTGCVIAWNSNKLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGNKPCNGVAGFNCYFPLRSYGFRPTYGVGHQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQGVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEYVNNSYECDIPIGAGICASYQTQTKSHRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLKRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKYFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNHNAQALNTLVKQLSSKFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKWPWYIWLGFIAGLIAIVMVTIMLCCMTSCCSCLKGCCSCGSCCKFDEDDSEPVLKGVKLHYT,1270,"Dadonaite et al., 2024",Bloom lab (dms-vep),journal,(spike mediated entry),SARS2_SPIKE,cell_entry
SARS2_KP311_spike_Dadonaite_binding,SARS2_KP311_spike_Dadonaite_binding.csv,SARS-CoV-2,Spike KP.3.1.1,binding,MFVFLVLLPLVSSQCVMPLFNLITTTQSYTNFTRGVYYPDKVFRSSVLHLTQDLFLPFFSNVTWFHAISGTNGTKRFDNPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIVNNATNVFIKVCEFQFCNDPFLDVYHKNNKSWMESESGVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPIIGRDFPQGFSALEPLVDLPIGINITRFQTLLALNRSYLTPGDSSSGWTAGAADYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNVTNLCPFHEVFNATRFASVYAWNRTRISNCVADYSVLYNFAPFFAFKCYGVSPTKLNDLCFTNVYADSFVIKGNEVSQIAPGQTGNIADYNYKLPDDFTGCVIAWNSNKLDSKHSGNYDYWYRSLRKSKLKPFERDISTEIYQAGNKPCKGKGPNCYFPLESYGFRPTYGVGHQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTKSNKKFLPFQQFGRDIVDTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQGVNCTEVSVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEYVNNSYECDIPIGAGICASYQTQTKSRRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLKRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKYFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLFSTASALGKLQDVVNHNAQALNTLVKQLSSKFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFLTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQLELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKWPWYIWLGFIAGLIAIVMVTIMLCCMTSCCSCLKGCCSCGS,1247,"Dadonaite et al., 2025b",Bloom lab (dms-vep),preprint,(ACE2 binding),SARS2_SPIKE,binding
SARS2_KP311_spike_Dadonaite_mAb_escape,SARS2_KP311_spike_Dadonaite_mAb_escape.csv,SARS-CoV-2,Spike KP.3.1.1,immune escape,MFVFLVLLPLVSSQCVMPLFNLITTTQSYTNFTRGVYYPDKVFRSSVLHLTQDLFLPFFSNVTWFHAISGTNGTKRFDNPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIVNNATNVFIKVCEFQFCNDPFLDVYHKNNKSWMESESGVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPIIGRDFPQGFSALEPLVDLPIGINITRFQTLLALNRSYLTPGDSSSGWTAGAADYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNVTNLCPFHEVFNATRFASVYAWNRTRISNCVADYSVLYNFAPFFAFKCYGVSPTKLNDLCFTNVYADSFVIKGNEVSQIAPGQTGNIADYNYKLPDDFTGCVIAWNSNKLDSKHSGNYDYWYRSLRKSKLKPFERDISTEIYQAGNKPCKGKGPNCYFPLESYGFRPTYGVGHQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTKSNKKFLPFQQFGRDIVDTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQGVNCTEVSVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEYVNNSYECDIPIGAGICASYQTQTKSRRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLKRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKYFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLFSTASALGKLQDVVNHNAQALNTLVKQLSSKFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFLTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQLELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKWPWYIWLGFIAGLIAIVMVTIMLCCMTSCCSCLKGCCSCGS,1247,"Dadonaite et al., 2025b",Bloom lab (dms-vep),preprint,"(mean of mAbs BD55-1205, SA55, VYD222)",SARS2_SPIKE,immune_escape
SARS2_RBD_Wuhan_Cao_mAb_escape,SARS2_RBD_Wuhan_Cao_mAb_escape.csv,SARS-CoV-2,RBD Wuhan-hu,immune escape,NITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKST,201,"Cao et al., 2022",Cao/Xie lab (PKU),journal,(mean of >=3 mAb escape scores; RBD 331-531),SARS2_RBD,immune_escape
ZIKV_E_MR766_mAb_escape,ZIKV_E_MR766_mAb_escape.csv,Zika virus,E,immune escape,IRCIGVSNRDFVEGMSGGTWVDVVLEHGGCVTVMAQDKPTVDIELVTTTVSNMAEVRSYCYEASISDMASDSRCPTQGEAYLDKQSDTQYVCKRTLVDRGWGNGCGLFGKGSLVTCAKFTCSKKMTGKSIQPENLEYRIMLSVHGSQHSGMIVNDTGYETDENRAKVEVTPNSPRAEATLGGFGSLGLDCEPRTGLDFSDLYYLTMNNKHWLVHKEWFHDIPLPWHAGADTGTPHWNNKEALVEFKDAHAKRQTVVVLGSQEGAVHTALAGALEAEMDGAKGKLFSGHLKCRLKMDKLRLKGVSYSLCTAAFTFTKVPAETLHGTVTVEVQYAGTDGPCKIPVQMAVDMQTLTPVGRLITANPVITESTENSKMMLELDPPFGDSYIVIGVGDKKITHHWHRSGSTIGKAFEATVRGAKRMAVLGDTAWDFGSVGGVFNSLGKGIHQIFGAAFKSLFGGMSWFSQILIGTLLVWLGLNTKNGSISLTCLALGGVMIFLSTAVSA,504,"Sourisseau et al., 2019; Kikawa et al., 2023",Bloom/Goo/Evans labs,journal,(mean of >=3/7 antibody diffsel maps),ZIKV_E,immune_escape
NIPAH_F_Larsen26_cell_entry,NIPAH_F_Larsen26_cell_entry.csv,Nipah virus,F,cell entry,HYEKLSKIGLVKGVTRKYKIKSNPLTKDIVIKMIPNVSNMSQCTGSVMENYKTRLNGILTPIKGALEIYKNNTHDLVGDVRLAGVIMAGVAIGIATAAQITAGVALYEAMKNADNINKLKSSIESTNEAVVKLQETAEKTVYVLTALQDYINTNLVPTIDKISCKQTELSLDLALSKYLSDLLFVFGPNLQDPVSNSMTIQAISQAFGGNYETLLRTLGYATEDFDDLLESDSITGQIIYVDLSSYYIIVRVYFPILTEIQQAYIQELLPVSFNNDNSEWISIVPNFILVRNTLISNIEIGFCLITKRSVICNQDYATPMTNNMRECLTGSTEKCPRELVVSSHVPRFALSNGVLFANCISVTCQCQTTGRAISQSGEQTLLMIDNTTCPTAVLGNVIISLGKYLGSVNYNSEGIAIGPPVFTDKVDISSQISSMNQSLQQSKDYIKEAQRLL,453,"Larsen et al., 2026",Bloom lab (dms-vep),published,"wt mismatch dropped: 0; CTdel construct, author sites 29-481",NIPAH_F,cell_entry
NIPAH_F_Larsen26_mAb_escape,NIPAH_F_Larsen26_mAb_escape.csv,Nipah virus,F,immune escape,HYEKLSKIGLVKGVTRKYKIKSNPLTKDIVIKMIPNVSNMSQCTGSVMENYKTRLNGILTPIKGALEIYKNNTHDLVGDVRLAGVIMAGVAIGIATAAQITAGVALYEAMKNADNINKLKSSIESTNEAVVKLQETAEKTVYVLTALQDYINTNLVPTIDKISCKQTELSLDLALSKYLSDLLFVFGPNLQDPVSNSMTIQAISQAFGGNYETLLRTLGYATEDFDDLLESDSITGQIIYVDLSSYYIIVRVYFPILTEIQQAYIQELLPVSFNNDNSEWISIVPNFILVRNTLISNIEIGFCLITKRSVICNQDYATPMTNNMRECLTGSTEKCPRELVVSSHVPRFALSNGVLFANCISVTCQCQTTGRAISQSGEQTLLMIDNTTCPTAVLGNVIISLGKYLGSVNYNSEGIAIGPPVFTDKVDISSQISSMNQSLQQSKDYIKEAQRLL,453,"Larsen et al., 2026",Bloom lab (dms-vep),published,mean of 6 mAbs (>=3 measured); wt mismatch dropped: 0,NIPAH_F,immune_escape
NIPAH_RBP_Larsen_minibinder_escape,NIPAH_RBP_Larsen_minibinder_escape.csv,Nipah virus,RBP (G),immune escape,MPAENKKVRFENTTSDKGKIPSKVIKSYYGTMDIKKINEGLLDSKILSAFNTVIALLGSIVIIVMNIMIIQNYTRSTDNQAVIKDALQGIQQQIKGLADKIGTEIGPKVSLIDTSSTITIPANIGLLGSKISQSTASINENVNEKCKFTLPPLKIHECNISCPNPLPFREYRPQTEGVSNLVGLPNNICLQKTSNQILKPKLISYTLPVVGQSGTCITDPLLAMDEGYFAYSHLERIGSCSRGVSKQRIIGVGEVLDRGDEVPSLFMTNVWTPPNPNTVYHCSAVYNNEFYYVLCAVSTVGDPILNSTYWSGSLMMTRLAVKPKSNGGGYNQHQLALRSIEKGRYDKVMPYGPSGIKQGDTLYFPAVGFLVRTEFKYNDSNCPITKCQYSKPENCRLSMGIRPNSHYILRSGLLKYNLSDGENPKVVFIEISDQRLSIGSPSKIYDSLGQPVFYQASFSWDTMIKFGDVLTVNPLVVNWRNNTVISRPGQSQCPRFNTCPEICWEGVYNDAFLIDRINWISAGVFLDSNQTAENPVFTVFKDNEILYRAQLASEDTNAQKTITNCFLLKNKIWCISLVEIYDTGDNVIRPKLFAVKIPEQCT,602,"Larsen et al., 2026",Bloom lab (dms-vep),preprint,"escape from designed minibinder sol23 (monomer+oligomer mean), not an antibody; out-of-range/wt-mismatch dropped: 4",NIPAH_RBP,immune_escape
LASSA_GP_Carr_sera_escape,LASSA_GP_Carr_sera_escape.csv,Lassa virus,GP,immune escape,MGQIVTFFQEVPHVIEEVMNIVLIALSVLAVLKGLYNFATCGLVGLVTFLLLCGRSCTTSLYKGVYELQTLELNMETLNMTMPLSCTKNNSHHYIMVGNETGLELTLTNTSIINHKFCNLSDAHKKNLYDHALMSIISTFHLSIPNFNQYEAMSCDFNGGKISVQYNLSHSYAGDAANHCGTVANGVLQTFMRMAWGGSYIALDSGRGNWDCIMTSYQYLIIQNTTWEDHCQFSRPSPIGYLGLLSQRTRDIYISRRLLGTFTWTLSDSEGKDTPGGYCLTRWMLIEAELKCFGNTAVAKCNEKHDEEFCDMLRLFDFNKQAIQRLKAEAQMSIQLINKAVNALINDQLIMKNHLRDIMGIPYCNYSKYWYLNHTTTGRTSLPKCWLVSNGSYLNETHFSDDIEQQADNMITEMLQKEYMERQGKTPLGLVDLFVFSTSFYLISIFLHLVKIPTHRHIVGKSCPKPHRLNHMGICSCGLYKQPGVPVKWKR,491,"Carr & Bloom, 2026",Bloom lab (dms-vep),preprint,mean of 13 Columbia/VRC sera (>=6 measured); wt mismatch dropped: 0,LASSA_GP,immune_escape
SARS2_BA2_spike_Crowe_mAb_escape,SARS2_BA2_spike_Crowe_mAb_escape.csv,SARS-CoV-2,Spike (BA.2),immune escape,MFVFLVLLPLVSSQCVNLITRTQSYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFDNPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLDVYYHKNNKSWMESEFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINLGRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFDEVFNATRFASVYAWNRKRISNCVADYSVLYNFAPFFAFKCYGVSPTKLNDLCFTNVYADSFVIRGNEVSQIAPGQTGNIADYNYKLPDDFTGCVIAWNSNKLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGNKPCNGVAGFNCYFPLRSYGFRPTYGVGHQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQGVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEYVNNSYECDIPIGAGICASYQTQTKSHRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLKRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKYFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNHNAQALNTLVKQLSSKFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKWPWYIWLGFIAGLIAIVMVTIMLCCMTSCCSCLKGCCSCGSCCKFDEDDSEPVLKGVKLHYT,1270,"Dadonaite & Bloom, 2026",Bloom lab (dms-vep),preprint,mean of 6 Crowe-lab mAbs (>=3 measured); author=Wuhan-Hu-1 ref numbering; wt mismatch dropped: 0,SARS2_SPIKE,immune_escape