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{"patient_id":"ANODE_SYNTH_2025_1073","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":11.0,"microsatellite_status":"MSS","pd_l1_tps_percent":7},"baseline_clinica... |
{"patient_id":"ANODE_SYNTH_2025_1074","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"EGFR L858R","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":11.5,"microsatellite_status":"MSS","pd_l1_tps_percent":4},"baseline_clinic... |
{"patient_id":"ANODE_SYNTH_2025_1075","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"EGFR L858R","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":2.8,"microsatellite_status":"MSS","pd_l1_tps_percent":14},"baseline_clinic... |
{"patient_id":"ANODE_SYNTH_2025_1076","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"ALK fusion","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":8.0,"microsatellite_status":"MSS","pd_l1_tps_percent":10},"baseline_clinica... |
{"patient_id":"ANODE_SYNTH_2025_1077","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"EGFR L858R","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":13.1,"microsatellite_status":"MSS","pd_l1_tps_percent":26},"baseline_clin... |
{"patient_id":"ANODE_SYNTH_2025_1078","cancer_type":"Non-small cell lung cancer","histology":"Squamous cell carcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"None (PD-L1 high)","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":13.9,"microsatellite_status":"MSS","pd_l1_tps_percent":33}... |
{"patient_id":"ANODE_SYNTH_2025_1079","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"EGFR L858R","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":14.3,"microsatellite_status":"MSS","pd_l1_tps_percent":32},"baseline_clini... |
{"patient_id":"ANODE_SYNTH_2025_1080","cancer_type":"Non-small cell lung cancer","histology":"Squamous cell carcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"None (PD-L1 high)","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":8.5,"microsatellite_status":"MSS","pd_l1_tps_percent":18},"... |
{"patient_id":"ANODE_SYNTH_2025_1081","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"ALK fusion","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":8.6,"microsatellite_status":"MSS","pd_l1_tps_percent":32},"baseline_clinica... |
{"patient_id":"ANODE_SYNTH_2025_1082","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"EGFR L858R","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":16.1,"microsatellite_status":"MSS","pd_l1_tps_percent":33},"baseline_clini... |
{"patient_id":"ANODE_SYNTH_2025_1083","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"ALK fusion","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":12.0,"microsatellite_status":"MSS","pd_l1_tps_percent":18},"baseline_clini... |
{"patient_id":"ANODE_SYNTH_2025_1084","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"EGFR exon 19 deletion","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":11.7,"microsatellite_status":"MSS","pd_l1_tps_percent":26},"ba... |
{"patient_id":"ANODE_SYNTH_2025_1085","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":11.8,"microsatellite_status":"MSS","pd_l1_tps_percent":20},"baseline_clinic... |
{"patient_id":"ANODE_SYNTH_2025_1086","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"EGFR exon 19 deletion","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":3.4,"microsatellite_status":"MSS","pd_l1_tps_percent":15},"bas... |
{"patient_id":"ANODE_SYNTH_2025_1087","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"EGFR L858R","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":9.8,"microsatellite_status":"MSS","pd_l1_tps_percent":22},"baseline_clinic... |
{"patient_id":"ANODE_SYNTH_2025_1088","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":3.7,"microsatellite_status":"MSS","pd_l1_tps_percent":24},"baseline_clinical... |
{"patient_id":"ANODE_SYNTH_2025_1089","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"NTRK fusion","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":2.5,"microsatellite_status":"MSS","pd_l1_tps_percent":4},"baseline_clinica... |
{"patient_id":"ANODE_SYNTH_2025_1090","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"ALK fusion","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":17.3,"microsatellite_status":"MSS","pd_l1_tps_percent":5},"baseline_clinic... |
{"patient_id":"ANODE_SYNTH_2025_1091","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"EGFR L858R","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":14.9,"microsatellite_status":"MSS","pd_l1_tps_percent":32},"baseline_clin... |
{"patient_id":"ANODE_SYNTH_2025_1092","cancer_type":"Non-small cell lung cancer","histology":"Squamous cell carcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"None (PD-L1 high)","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":8.4,"microsatellite_status":"MSS","pd_l1_tps_percent":10},... |
{"patient_id":"ANODE_SYNTH_2025_1093","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":9.2,"microsatellite_status":"MSS","pd_l1_tps_percent":13},"baseline_clinical... |
{"patient_id":"ANODE_SYNTH_2025_1094","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"ALK fusion","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":13.0,"microsatellite_status":"MSS","pd_l1_tps_percent":17},"baseline_clini... |
{"patient_id":"ANODE_SYNTH_2025_1095","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":10.9,"microsatellite_status":"MSS","pd_l1_tps_percent":13},"baseline_clinic... |
{"patient_id":"ANODE_SYNTH_2025_1096","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":3.0,"microsatellite_status":"MSS","pd_l1_tps_percent":29},"baseline_clinical... |
{"patient_id":"ANODE_SYNTH_2025_1097","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"EGFR L858R","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":16.6,"microsatellite_status":"MSS","pd_l1_tps_percent":15},"baseline_clini... |
{"patient_id":"ANODE_SYNTH_2025_1098","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"ALK fusion","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":7.6,"microsatellite_status":"MSS","pd_l1_tps_percent":2},"baseline_clinical... |
{"patient_id":"ANODE_SYNTH_2025_1099","cancer_type":"Non-small cell lung cancer","histology":"Squamous cell carcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"None (PD-L1 high)","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":6.8,"microsatellite_status":"MSS","pd_l1_tps_percent":32},... |
{"patient_id":"ANODE_SYNTH_2025_1100","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"EGFR L858R","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":12.1,"microsatellite_status":"MSS","pd_l1_tps_percent":21},"baseline_clin... |
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