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{"patient_id":"ANODE_SYNTH_2025_1573","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":11.9,"microsatellite_status":"MSS","pd_l1_tps_percent":23},"baseline_clinica... |
{"patient_id":"ANODE_SYNTH_2025_1574","cancer_type":"Non-small cell lung cancer","histology":"Squamous cell carcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"None (PD-L1 high)","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":4.6,"microsatellite_status":"MSS","pd_l1_tps_percent":35},... |
{"patient_id":"ANODE_SYNTH_2025_1575","cancer_type":"Non-small cell lung cancer","histology":"Squamous cell carcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"None (PD-L1 high)","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":12.8,"microsatellite_status":"MSS","pd_l1_tps_percent":22},... |
{"patient_id":"ANODE_SYNTH_2025_1576","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"EGFR exon 19 deletion","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":16.3,"microsatellite_status":"MSS","pd_l1_tps_percent":20},"bas... |
{"patient_id":"ANODE_SYNTH_2025_1577","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":16.1,"microsatellite_status":"MSS","pd_l1_tps_percent":26},"baseline_clinic... |
{"patient_id":"ANODE_SYNTH_2025_1578","cancer_type":"Non-small cell lung cancer","histology":"Squamous cell carcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"None (PD-L1 high)","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":17.3,"microsatellite_status":"MSS","pd_l1_tps_percent":15},... |
{"patient_id":"ANODE_SYNTH_2025_1579","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"ALK fusion","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":3.5,"microsatellite_status":"MSS","pd_l1_tps_percent":30},"baseline_clinic... |
{"patient_id":"ANODE_SYNTH_2025_1580","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"EGFR L858R","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":7.3,"microsatellite_status":"MSS","pd_l1_tps_percent":13},"baseline_clini... |
{"patient_id":"ANODE_SYNTH_2025_1581","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":10.2,"microsatellite_status":"MSS","pd_l1_tps_percent":19},"baseline_clinica... |
{"patient_id":"ANODE_SYNTH_2025_1582","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":5.0,"microsatellite_status":"MSS","pd_l1_tps_percent":33},"baseline_clinical... |
{"patient_id":"ANODE_SYNTH_2025_1583","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":12.2,"microsatellite_status":"MSS","pd_l1_tps_percent":25},"baseline_clinic... |
{"patient_id":"ANODE_SYNTH_2025_1584","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"EGFR L858R","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":5.2,"microsatellite_status":"MSS","pd_l1_tps_percent":0},"baseline_clinica... |
{"patient_id":"ANODE_SYNTH_2025_1585","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":3.5,"microsatellite_status":"MSS","pd_l1_tps_percent":24},"baseline_clinical... |
{"patient_id":"ANODE_SYNTH_2025_1586","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"EGFR L858R","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":10.0,"microsatellite_status":"MSS","pd_l1_tps_percent":9},"baseline_clini... |
{"patient_id":"ANODE_SYNTH_2025_1587","cancer_type":"Non-small cell lung cancer","histology":"Squamous cell carcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"None (PD-L1 high)","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":2.6,"microsatellite_status":"MSS","pd_l1_tps_percent":20},... |
{"patient_id":"ANODE_SYNTH_2025_1588","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"EGFR L858R","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":16.9,"microsatellite_status":"MSS","pd_l1_tps_percent":25},"baseline_clini... |
{"patient_id":"ANODE_SYNTH_2025_1589","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"EGFR exon 19 deletion","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":2.5,"microsatellite_status":"MSS","pd_l1_tps_percent":27},"base... |
{"patient_id":"ANODE_SYNTH_2025_1590","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"ALK fusion","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":15.0,"microsatellite_status":"MSS","pd_l1_tps_percent":4},"baseline_clinic... |
{"patient_id":"ANODE_SYNTH_2025_1591","cancer_type":"Non-small cell lung cancer","histology":"Squamous cell carcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"None (PD-L1 high)","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":12.5,"microsatellite_status":"MSS","pd_l1_tps_percent":15},... |
{"patient_id":"ANODE_SYNTH_2025_1592","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"ALK fusion","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":16.9,"microsatellite_status":"MSS","pd_l1_tps_percent":26},"baseline_clinic... |
{"patient_id":"ANODE_SYNTH_2025_1593","cancer_type":"Non-small cell lung cancer","histology":"Squamous cell carcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"None (PD-L1 high)","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":11.3,"microsatellite_status":"MSS","pd_l1_tps_percent":12}... |
{"patient_id":"ANODE_SYNTH_2025_1594","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"EGFR exon 19 deletion","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":12.4,"microsatellite_status":"MSS","pd_l1_tps_percent":4},"base... |
{"patient_id":"ANODE_SYNTH_2025_1595","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":8.3,"microsatellite_status":"MSS","pd_l1_tps_percent":35},"baseline_clinica... |
{"patient_id":"ANODE_SYNTH_2025_1596","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":16.4,"microsatellite_status":"MSS","pd_l1_tps_percent":16},"baseline_clinica... |
{"patient_id":"ANODE_SYNTH_2025_1597","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"EGFR exon 19 deletion","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":11.2,"microsatellite_status":"MSS","pd_l1_tps_percent":22},"ba... |
{"patient_id":"ANODE_SYNTH_2025_1598","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"ALK fusion","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":16.5,"microsatellite_status":"MSS","pd_l1_tps_percent":11},"baseline_clinic... |
{"patient_id":"ANODE_SYNTH_2025_1599","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"ALK fusion","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":9.8,"microsatellite_status":"MSS","pd_l1_tps_percent":1},"baseline_clinica... |
{"patient_id":"ANODE_SYNTH_2025_1600","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"EGFR L858R","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":13.1,"microsatellite_status":"MSS","pd_l1_tps_percent":13},"baseline_clini... |
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