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{"patient_id":"ANODE_SYNTH_2025_1673","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":17.5,"microsatellite_status":"MSS","pd_l1_tps_percent":14},"baseline_clinic... |
{"patient_id":"ANODE_SYNTH_2025_1674","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":7.6,"microsatellite_status":"MSS","pd_l1_tps_percent":15},"baseline_clinical... |
{"patient_id":"ANODE_SYNTH_2025_1675","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"ALK fusion","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":16.2,"microsatellite_status":"MSS","pd_l1_tps_percent":30},"baseline_clinic... |
{"patient_id":"ANODE_SYNTH_2025_1676","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"EGFR L858R","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":8.9,"microsatellite_status":"MSS","pd_l1_tps_percent":15},"baseline_clini... |
{"patient_id":"ANODE_SYNTH_2025_1677","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":13.3,"microsatellite_status":"MSS","pd_l1_tps_percent":2},"baseline_clinical... |
{"patient_id":"ANODE_SYNTH_2025_1678","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"ALK fusion","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":14.3,"microsatellite_status":"MSS","pd_l1_tps_percent":0},"baseline_clinic... |
{"patient_id":"ANODE_SYNTH_2025_1679","cancer_type":"Non-small cell lung cancer","histology":"Squamous cell carcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"None (PD-L1 high)","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":7.9,"microsatellite_status":"MSS","pd_l1_tps_percent":35},"... |
{"patient_id":"ANODE_SYNTH_2025_1680","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":13.4,"microsatellite_status":"MSS","pd_l1_tps_percent":0},"baseline_clinical... |
{"patient_id":"ANODE_SYNTH_2025_1681","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"EGFR exon 19 deletion","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":4.3,"microsatellite_status":"MSS","pd_l1_tps_percent":9},"basel... |
{"patient_id":"ANODE_SYNTH_2025_1682","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"EGFR L858R","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":3.4,"microsatellite_status":"MSS","pd_l1_tps_percent":35},"baseline_clini... |
{"patient_id":"ANODE_SYNTH_2025_1683","cancer_type":"Non-small cell lung cancer","histology":"Squamous cell carcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"None (PD-L1 high)","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":17.7,"microsatellite_status":"MSS","pd_l1_tps_percent":14},... |
{"patient_id":"ANODE_SYNTH_2025_1684","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":5.0,"microsatellite_status":"MSS","pd_l1_tps_percent":9},"baseline_clinical"... |
{"patient_id":"ANODE_SYNTH_2025_1685","cancer_type":"Non-small cell lung cancer","histology":"Squamous cell carcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"None (PD-L1 high)","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":2.7,"microsatellite_status":"MSS","pd_l1_tps_percent":31},"... |
{"patient_id":"ANODE_SYNTH_2025_1686","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"ALK fusion","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":17.8,"microsatellite_status":"MSS","pd_l1_tps_percent":26},"baseline_clini... |
{"patient_id":"ANODE_SYNTH_2025_1687","cancer_type":"Non-small cell lung cancer","histology":"Squamous cell carcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"None (PD-L1 high)","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":6.6,"microsatellite_status":"MSS","pd_l1_tps_percent":12},"... |
{"patient_id":"ANODE_SYNTH_2025_1688","cancer_type":"Non-small cell lung cancer","histology":"Squamous cell carcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"None (PD-L1 high)","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":15.1,"microsatellite_status":"MSS","pd_l1_tps_percent":19},... |
{"patient_id":"ANODE_SYNTH_2025_1689","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"ALK fusion","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":11.7,"microsatellite_status":"MSS","pd_l1_tps_percent":31},"baseline_clinic... |
{"patient_id":"ANODE_SYNTH_2025_1690","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":16.9,"microsatellite_status":"MSS","pd_l1_tps_percent":5},"baseline_clinical... |
{"patient_id":"ANODE_SYNTH_2025_1691","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"EGFR exon 19 deletion","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":2.7,"microsatellite_status":"MSS","pd_l1_tps_percent":0},"base... |
{"patient_id":"ANODE_SYNTH_2025_1692","cancer_type":"Non-small cell lung cancer","histology":"Squamous cell carcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"None (PD-L1 high)","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":6.1,"microsatellite_status":"MSS","pd_l1_tps_percent":13},"... |
{"patient_id":"ANODE_SYNTH_2025_1693","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"EGFR exon 19 deletion","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":3.5,"microsatellite_status":"MSS","pd_l1_tps_percent":35},"bas... |
{"patient_id":"ANODE_SYNTH_2025_1694","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"EGFR exon 19 deletion","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":12.8,"microsatellite_status":"MSS","pd_l1_tps_percent":0},"base... |
{"patient_id":"ANODE_SYNTH_2025_1695","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":12.7,"microsatellite_status":"MSS","pd_l1_tps_percent":33},"baseline_clinica... |
{"patient_id":"ANODE_SYNTH_2025_1696","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"EGFR L858R","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":17.5,"microsatellite_status":"MSS","pd_l1_tps_percent":0},"baseline_clinic... |
{"patient_id":"ANODE_SYNTH_2025_1697","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"ALK fusion","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":2.3,"microsatellite_status":"MSS","pd_l1_tps_percent":13},"baseline_clinica... |
{"patient_id":"ANODE_SYNTH_2025_1698","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"EGFR exon 19 deletion","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":17.0,"microsatellite_status":"MSS","pd_l1_tps_percent":5},"base... |
{"patient_id":"ANODE_SYNTH_2025_1699","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"EGFR exon 19 deletion","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":12.7,"microsatellite_status":"MSS","pd_l1_tps_percent":3},"bas... |
{"patient_id":"ANODE_SYNTH_2025_1700","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"ALK fusion","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":4.5,"microsatellite_status":"MSS","pd_l1_tps_percent":15},"baseline_clinic... |
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