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{"patient_id":"ANODE_SYNTH_2025_1773","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":13.0,"microsatellite_status":"MSS","pd_l1_tps_percent":32},"baseline_clinica... |
{"patient_id":"ANODE_SYNTH_2025_1774","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"ALK fusion","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":4.9,"microsatellite_status":"MSS","pd_l1_tps_percent":6},"baseline_clinica... |
{"patient_id":"ANODE_SYNTH_2025_1775","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"ALK fusion","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":13.6,"microsatellite_status":"MSS","pd_l1_tps_percent":35},"baseline_clini... |
{"patient_id":"ANODE_SYNTH_2025_1776","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"EGFR L858R","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":11.4,"microsatellite_status":"MSS","pd_l1_tps_percent":22},"baseline_clini... |
{"patient_id":"ANODE_SYNTH_2025_1777","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"ALK fusion","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":2.1,"microsatellite_status":"MSS","pd_l1_tps_percent":30},"baseline_clinica... |
{"patient_id":"ANODE_SYNTH_2025_1778","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"EGFR exon 19 deletion","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":14.9,"microsatellite_status":"MSS","pd_l1_tps_percent":8},"base... |
{"patient_id":"ANODE_SYNTH_2025_1779","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"EGFR exon 19 deletion","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":10.4,"microsatellite_status":"MSS","pd_l1_tps_percent":25},"bas... |
{"patient_id":"ANODE_SYNTH_2025_1780","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"ALK fusion","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":13.7,"microsatellite_status":"MSS","pd_l1_tps_percent":30},"baseline_clinic... |
{"patient_id":"ANODE_SYNTH_2025_1781","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"EGFR L858R","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":11.6,"microsatellite_status":"MSS","pd_l1_tps_percent":23},"baseline_clin... |
{"patient_id":"ANODE_SYNTH_2025_1782","cancer_type":"Non-small cell lung cancer","histology":"Squamous cell carcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"None (PD-L1 high)","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":4.9,"microsatellite_status":"MSS","pd_l1_tps_percent":33},"... |
{"patient_id":"ANODE_SYNTH_2025_1783","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"ALK fusion","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":8.2,"microsatellite_status":"MSS","pd_l1_tps_percent":12},"baseline_clinica... |
{"patient_id":"ANODE_SYNTH_2025_1784","cancer_type":"Non-small cell lung cancer","histology":"Squamous cell carcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"None (PD-L1 high)","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":9.5,"microsatellite_status":"MSS","pd_l1_tps_percent":16},"... |
{"patient_id":"ANODE_SYNTH_2025_1785","cancer_type":"Non-small cell lung cancer","histology":"Squamous cell carcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"None (PD-L1 high)","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":6.5,"microsatellite_status":"MSS","pd_l1_tps_percent":18},"... |
{"patient_id":"ANODE_SYNTH_2025_1786","cancer_type":"Non-small cell lung cancer","histology":"Squamous cell carcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"None (PD-L1 high)","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":13.9,"microsatellite_status":"MSS","pd_l1_tps_percent":17},... |
{"patient_id":"ANODE_SYNTH_2025_1787","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"EGFR L858R","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":17.1,"microsatellite_status":"MSS","pd_l1_tps_percent":12},"baseline_clin... |
{"patient_id":"ANODE_SYNTH_2025_1788","cancer_type":"Non-small cell lung cancer","histology":"Squamous cell carcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"None (PD-L1 high)","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":15.6,"microsatellite_status":"MSS","pd_l1_tps_percent":31}... |
{"patient_id":"ANODE_SYNTH_2025_1789","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"NTRK fusion","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":13.6,"microsatellite_status":"MSS","pd_l1_tps_percent":1},"baseline_clinic... |
{"patient_id":"ANODE_SYNTH_2025_1790","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"EGFR L858R","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":4.3,"microsatellite_status":"MSS","pd_l1_tps_percent":21},"baseline_clini... |
{"patient_id":"ANODE_SYNTH_2025_1791","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":12.4,"microsatellite_status":"MSS","pd_l1_tps_percent":31},"baseline_clinica... |
{"patient_id":"ANODE_SYNTH_2025_1792","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":4.9,"microsatellite_status":"MSS","pd_l1_tps_percent":30},"baseline_clinical... |
{"patient_id":"ANODE_SYNTH_2025_1793","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"ALK fusion","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":14.1,"microsatellite_status":"MSS","pd_l1_tps_percent":35},"baseline_clinic... |
{"patient_id":"ANODE_SYNTH_2025_1794","cancer_type":"Non-small cell lung cancer","histology":"Squamous cell carcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"None (PD-L1 high)","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":12.2,"microsatellite_status":"MSS","pd_l1_tps_percent":28}... |
{"patient_id":"ANODE_SYNTH_2025_1795","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":10.2,"microsatellite_status":"MSS","pd_l1_tps_percent":16},"baseline_clinic... |
{"patient_id":"ANODE_SYNTH_2025_1796","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":10.0,"microsatellite_status":"MSS","pd_l1_tps_percent":34},"baseline_clinica... |
{"patient_id":"ANODE_SYNTH_2025_1797","cancer_type":"Non-small cell lung cancer","histology":"Squamous cell carcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"None (PD-L1 high)","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":7.4,"microsatellite_status":"MSS","pd_l1_tps_percent":12},... |
{"patient_id":"ANODE_SYNTH_2025_1798","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":12.8,"microsatellite_status":"MSS","pd_l1_tps_percent":28},"baseline_clinica... |
{"patient_id":"ANODE_SYNTH_2025_1799","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"EGFR exon 19 deletion","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":7.9,"microsatellite_status":"MSS","pd_l1_tps_percent":21},"base... |
{"patient_id":"ANODE_SYNTH_2025_1800","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"EGFR L858R","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":9.1,"microsatellite_status":"MSS","pd_l1_tps_percent":8},"baseline_clinic... |
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