Can you summarize the different types of thalassemia and how they affect the body?: Thalassemia is a blood disorder that causes mild or severe anemia (Antonio, 1993). This happens when people do not have enough hemoglobin and is caused by the inheritance of a defective gene (Nathan, 1998). Thalassemia is passed on from a parent to children through their genes (Simon, 1999). The name thalassemia comes from the Greek word "thalassa" meaning "the sea" because the condition was first described in populations living near the Mediterranean Sea (Nathan, 1998). However, the disease is also prevalent in Africa, Middle East, South Asia, and pacific descent (Simon, 1999). Moreover, thalassemia causes an immense disruption in the hemoglobin synthesis (Nathan, 1998). Although, there are two different types of thalassemia, alpha, and beta thalassemia they both affect the body.
Alpha-thalassemia occurs most commonly in people from Southeast Asia and China (Ghosh, 1994). Its is caused when the hemoglobin does not produce enough alpha protein (Ghosh, 1994). The most severe form of alpha thalassemia causes (stillbirth, and death of fetus before delivery) (Ghosh, 1994).
Whereas, beta thalassemia, is caused by a mutation in the beta globin chain (Nathan, 1998). Genes from both parents must be inherited to acquire the major form of this disease (Simon, 1999). In beta thalassemia major children are normal at birth, but develop anemia during the first year of life (Simon, 1999). The alpha and beta thalassemia's are distinct diseases that affect the body in different ways. Therefore, the symptoms of thalassemia, which are paleness, tiredness, dark urine, and spleen enlargement all, depend on the type and severity of the disease ( Simon, 1999).
WriteWork contributors. "Thalassemia" WriteWork.com. WriteWork.com, 19 February, 2007. Web. 19 Apr. 2019.
Can you summarize the different types of thalassemia and how they affect the body?: Thalassemia is a blood disorder that causes mild or severe anemia (Antonio, 1993). This happens when people do not have enough hemoglobin and is caused by the inheritance of a defective gene (Nathan, 1998). Thalassemia is passed on from a parent to children through their genes (Simon, 1999). The name thalassemia comes from the Greek word "thalassa" meaning "the sea" because the condition was first described in populations living near the Mediterranean Sea (Nathan, 1998). However, the disease is also prevalent in Africa, Middle East, South Asia, and pacific descent (Simon, 1999). Moreover, thalassemia causes an immense disruption in the hemoglobin synthesis (Nathan, 1998). Although, there are two different types of thalassemia, alpha, and beta thalassemia they both affect the body.
Alpha-thalassemia occurs most commonly in people from Southeast Asia and China (Ghosh, 1994). Its is caused when the hemoglobin does not produce enough alpha protein (Ghosh, 1994). The most severe form of alpha thalassemia causes (stillbirth, and death of fetus before delivery) (Ghosh, 1994).
Whereas, beta thalassemia, is caused by a mutation in the beta globin chain (Nathan, 1998). Genes from both parents must be inherited to acquire the major form of this disease (Simon, 1999). In beta thalassemia major children are normal at birth, but develop anemia during the first year of life (Simon, 1999). The alpha and beta thalassemia's are distinct diseases that affect the body in different ways. Therefore, the symptoms of thalassemia, which are paleness, tiredness, dark urine, and spleen enlargement all, depend on the type and severity of the disease ( Simon, 1999).
WriteWork contributors. "Thalassemia" WriteWork.com. WriteWork.com, 19 February, 2007. Web. 19 Apr. 2019.
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Thalassemia is a blood disorder caused by an inheritance of a defective gene. There are two types of thalassemia, alpha, and beta thalassemia. Alpha-thalassemia occurs most commonly in people from Southeast Asia and China, and the most severe form can cause stillbirth. Beta-thalassemia is caused by a mutation in the beta globin chain and requires genes from both parents to acquire the major form of the disease. Symptoms of thalassemia include paleness, tiredness, dark urine, and spleen enlargement, which vary in severity depending on the type of thalassemia.
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Can you tell me more about how thalassemia affects the production of hemoglobin?
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Thalassemia affects the production of hemoglobin by disrupting the synthesis of alpha and beta globin chains that make up hemoglobin. Hemoglobin is a protein in red blood cells that carries oxygen from the lungs to the body's tissues. 

People with thalassemia produce less hemoglobin, resulting in anemia or a reduced number of circulating red blood cells. Alpha-thalassemia is caused when the hemoglobin does not produce enough alpha protein. Beta-thalassemia, on the other hand, occurs when there is a mutation in the beta globin chain, leading to a decreased amount of beta globin protein. 

The severity of thalassemia depends on the number of defective genes inherited, with more defective genes resulting in more severe symptoms. In the most severe form of beta-thalassemia, known as beta-thalassemia major, there is a complete absence or a significant reduction in the beta-globin chains. As a result, patients with beta-thalassemia major require regular blood transfusions and iron-chelation therapy to manage their symptoms.
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