title: Multidrug Resistance of &lt;i&gt;F. tularensis&lt;/i&gt; subsp. &lt;i&gt;holarctica&lt;/i&gt;, Epizootiological and Epidemiological Analysis of the Situation on Tularemia in the Russian Federation in 2022 and Forecast for 2023
abstract: The review provides concise information on the innate ability of cells of the tularemia pathogen, Francisella tularensis subsp. Holarctica , to resist antimicrobials through a variety of mechanisms, leading to its multi-resistance. In total, taking into account new territories, 120 cases of human infection were registered in the Russian Federation in 2022. Epizootic manifestations of the infection of varying degrees of intensity were detected in 58 constituent entities. Against this background, 
journal: Problems of Particularly Dangerous Infections