title: Changes in the Parameters of Systemic Hemodynamics and Perfusion during Laparoscopic Cholecystectomy in Patients with Acute Cholecystitis and Possible Correction Methods
abstract: This article presents a clinical and laboratory assessment of the effectiveness of the author's method for pharmacological correction of hypoxic changes at acute pneumoperitoneum in patients with acute calculous cholecystitis (ACC) during laparoscopic cholecystectomy (LCE) (Patent of Ukraine No. 119602). The application of the developed technique allows leveling of ischemic and reperfusion changes that occur during LCE in ACC patients by protectively affecting blood lactate level, statistically 
journal: International Journal of Biomedicine