title: [Detection of cytochrome P4502C19 gene polymorphism to optimize therapy of acid-dependent diseases].
abstract: The patients were divided into 3 groups based on the results of the test. 12 (37.5%) of them had fast-type metabolism (mean delta over base (DOB) 4.725%+-0.3), 14 (43.75%) had intermediate metabolism (mean DOB 2.44±0.162%) and 6 (18,75%) had slow metabolism (mean DOB 0.85±0.22%). The study showed the prevalence of fast and intermediate type metabolism in the inhabitants of Crimea which suggests the necessity of correction of standard PPI doses.
journal: PubMed