title: Neuroprotective Potential of Tamarillo (Cyphomandra betacea) Epicarp Extracts Obtained by Sustainable Extraction Process
abstract: Tamarillo (<i>Cyphomandra betacea</i> (Cav.) Sendt.), or tree tomato, is a tropical fruit from the Andean region of South America; it is highly rich in vitamins, minerals, and polyphenolic compounds. In this study, extracts from tamarillo epicarp (TE) were obtained by pressurized liquid extraction (PLE), and their <i>in-vitro</i> neuroprotective potential was assessed. A central composite design with response surface methodology was performed to optimize PLE as a function of solvent composition 
journal: Frontiers in Nutrition