title: Unusual biaryl torsional strain promotes reactivity in Cu-catalyzed Sommelet–Hauser rearrangement
abstract: A Cu-catalyzed Sommelet-Hauser dearomatization of dihydrophenanthridine and diazo compounds is reported for the synthesis of spiro-indolines. A spiro-structure with adjacent quaternary and tertiary carbon centers was constructed in one step as a single isomer. Increasing steric hindrance by introducing <i>ortho</i>-substituents dramatically improved substrate reactivity in this transformation.
journal: Chemical Science