title: &lt;p&gt;Use of levosimendan in acute and advanced heart failure: short review on available real-world data&lt;/p&gt;
abstract: Published data have shown potential advantages of levosimendan in the management of acute decompensated heart failure and advanced heart failure when standard medical therapies threaten hemodynamics and organ perfusion are unable to alleviate clinical symptoms. Levosimendan distinguishes itself from other catecholaminergic inotropes by its three mechanisms of action: positive inotropy, vasodilation, and cardioprotection. In addition, its pharmacokinetics allow for a longer duration of action fro
journal: Therapeutics and Clinical Risk Management