title: Potential mechanisms and effects of melatonin-regulated Nrf2/HO-1 pathway on acute lung injury due to formaldehyde exposure
abstract: Abstract Acute lung injury is a topic of great interest in critical care medicine due to its high mortality rates. The lungs are the immediate target organ for formaldehyde inhalation damage. Lung damage and fibrosis are the most important outcomes of severe and acute lung disease and pose a serious threat to human health. Melatonin (MT), a natural bioactive compound with anti-inflammatory and antioxidant properties, However, it is not clear whether MT can prevent FA-induced acute lung injury (A
journal: bioRxiv (Cold Spring Harbor Laboratory)