title: Molecular docking and dynamics simulation of FDA approved drugs to identify potential ligands for mitoNEET protein
abstract: It is believed that mitochondrial dysfunction is considered an essential part in the pathology of some diseases like Parkinson’s disease, Alzheimer’s disease and diabetes mellitus. Given the complex pathological process of these diseases, mitochondria directed therapy may show some promises towards treating and attenuating disease progression. In this regard, the mitochondrial protein mitoNEET seems to play an important role in regulating cellular bioenergetics. This iron-sulfur protein is a wel