# Source and novelty audit

Search date: 19 September 2026. The review is targeted and non-exhaustive; it cannot establish research or patent priority. The manuscript distinguishes new derivation from established ingredients. No third-party full papers are bundled.

| Reference | Evidence accessed | Use and limit |
|---|---|---|
| Soloveichik & Winfree, shape complexity | Primary arXiv abstract and bibliographic record, arXiv:cs/0412096 | Establishes prior connection to Kolmogorov complexity; not a new claim here |
| Doty et al., intrinsic universality | Primary arXiv abstract and record, arXiv:1111.3097 | Prior universal tile system and distributed genome language |
| Winfree & Bekbolatov, proofreading | Publisher chapter page and abstract, DOI 10.1007/978-3-540-24628-2_13 | Prior error-correction construction; no copied proof |
| Woods et al., molecular algorithms | Publisher abstract, metadata, reference list; author-repository result | 355 tile species, 21 selected algorithms, reported aggregate tile error; not a universal error parameter |
| Gomez et al., active tile universality | Primary arXiv abstract and proceedings record, arXiv:2407.11545 | Formal universality and approximate formal state count |
| Holmes-Cerfon & Wyart, hierarchy | Primary arXiv abstract and rendered manuscript, arXiv:2501.02611 | Hierarchical interaction design predates this report |
| Benoist & Sartori, assembly factors | Primary APS abstract and dated publication metadata | Recent adjacent kinetic principle; full-paper novelty comparison not completed |
| Michelson et al., inorganic frameworks (2024) | Author-laboratory hosted first page/abstract and publication record | Restricted material conversion precedent; not arbitrary chemistry |
| Michelson et al., devices (2025) | Primary publication metadata and authors' laboratory research highlight | Framework photocurrent and conversion precedent; publisher full text failed and PMC was blocked by a browser check |
| Teng et al., patterning (2025) | Primary publisher article, abstract, and methods context | Large-area externally patterned assembly, not seed-only arbitrary structures |
| Nguyen & Vaikuntanathan, nonequilibrium assembly | Primary publisher PDF text and bibliographic record | Thermodynamic precedent; publisher HTML redirected to a cookie page |

All bibliographic URLs and titles appear in the manuscript. The inaccessible full texts are not represented as fully reviewed. General probability, conservation, and diffusion derivations were performed explicitly in this report. Their standard mathematical ingredients are not claimed as new.

## Novelty boundary

Candidate original contribution: the specific reliability-access co-design window and its finite optimal exponent under redundant-volume-dependent depletion. This is an original derivation *within this document*, with priority unverified. The key novelty question for expert review is whether equivalent coupled reliability/transport/conversion bounds already exist in algorithmic assembly, reliable distributed systems, reaction-network design, or manufacturing-process optimization.

No new DNA motif, nanoparticle synthesis, working inorganic repair mechanism, molecular compiler, universal manufacturing phase transition, or successful general-purpose device platform is claimed.