Publish reviewed GAMBA evaluation dataset
Browse files
README.md
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---
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pretty_name: "GAMBA Functional Region Multiclass"
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license: mit
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tags:
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- biology
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- genomics
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- dna
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- genome-language-model
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- benchmark
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- functional-genomics
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- multiclass-classification
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- hg38
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- parquet
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configs:
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- config_name: full
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data_files:
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- split: all
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path: functional-multiclass-gamba-full.parquet
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- config_name: 100bp
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data_files:
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- split: all
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path: functional-multiclass-gamba-100bp.parquet
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- config_name: full-noncoding-added
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data_files:
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- split: all
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path: functional-multiclass-gamba-full-noncoding-added.parquet
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- config_name: 100bp-noncoding-added
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data_files:
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- split: all
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path: functional-multiclass-gamba-100bp-noncoding-added.parquet
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---
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# GAMBA Functional Region Multiclass
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This dataset packages GAMBA's multiclass functional-region benchmark. Each row
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is an annotated feature labeled by its functional category.
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The full-region and 100 bp pooling variants are separate Hugging Face configs.
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Both retain the same GAMBA-oriented context sequence; `pool_start` and
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`pool_end` select either the complete ROI or a deterministic 100 bp subspan.
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ROIs shorter than 100 bp are absent from the 100 bp configs.
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GAMBA's evaluator selects the 100 bp subspan using Python's process-randomized
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`hash()`. This release uses BLAKE2 over the same seed, category, and pair ID so
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the saved subset is stable across machines.
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## Configs
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| Config | Train rows | Test rows | Total | Pooling span |
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|---|---:|---:|---:|---|
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| `full` | 67,846 | 16,991 | 84,837 | complete ROI |
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| `100bp` | 46,862 | 11,781 | 58,643 | 100 bp |
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| `full-noncoding-added` | 75,363 | 18,917 | 94,280 | complete ROI |
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| `100bp-noncoding-added` | 54,028 | 13,595 | 67,623 | 100 bp |
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The two `noncoding-added` configs are explicit extensions from
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[Gamba-Processing](https://github.com/TaykhoomDalal/Gamba-Processing), not an
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additional category emitted by GAMBA's current `create_eval_data.py`.
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## Loading
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```python
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from datasets import load_dataset
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full = load_dataset(
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"Taykhoom/functional-multiclass-gamba",
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"full",
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split="all",
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)
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train = full.filter(lambda row: row["split"] == "train")
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test = full.filter(lambda row: row["split"] == "test")
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```
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## Columns
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| Column | Description |
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|---|---|
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| `split`, `label` | Probe/fine-tuning `train` or held-out `test`; `label` is the functional category. |
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| `sequence` | Strand-oriented GAMBA context of at most 2,048 bp. |
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| `pair_id` | Stable GAMBA feature/control identifier. |
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| `category`, `scope` | Functional category and `full` or `100bp`. |
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| `chrom`, `start`, `end`, `strand` | Zero-based, half-open hg38 feature coordinates. |
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| `context_start`, `context_end` | Forward-genome coordinates of `sequence`. |
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| `roi_start`, `roi_end` | Full feature offsets within `sequence`. |
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| `pool_start`, `pool_end` | Full-ROI or fixed 100 bp pooling span. |
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| `name` | Source annotation name. |
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## Data source and processing
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The processing code reproduces the ten-category BED output from
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[Microsoft GAMBA](https://github.com/microsoft/gamba) commit `e83984e`
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byte-for-byte, then freezes all GAMBA autosomes plus `chrX` in parquet.
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The GAMBA models were pretrained on the chromosomes marked `train`. The paper's
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zero-shot result used the frozen models on `chr2`, `chr3`, `chr16`, and
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`chr22`, which are marked `test`; no task-specific model was fitted on these
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benchmark rows. Use only `test` to reproduce that paper subset. The `train`
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rows are provided for probing/fine-tuning or broader chromosome evaluation.
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## Citation
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Please cite the GAMBA paper:
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Consens, M. E. et al. *Predicting evolutionary rate as a pretraining task
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improves genome language model representations*. bioRxiv (2026).
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[doi:10.64898/2026.02.02.703275](https://doi.org/10.64898/2026.02.02.703275).
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A conference version is available on
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[OpenReview](https://openreview.net/forum?id=dkgM2ale4U).
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```bibtex
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@article{consens2026predicting,
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title = {Predicting evolutionary rate as a pretraining task improves genome language model representations},
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author = {Consens, Micaela Elisa and Yang, Kevin K. and Hall, Jimmy and Conard, Ashley Mae and Wang, Bo and Crawford, Lorin and Moses, Alan and Lu, Alex X.},
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journal = {bioRxiv},
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year = {2026},
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doi = {10.64898/2026.02.02.703275},
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url = {https://doi.org/10.64898/2026.02.02.703275}
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}
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```
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## License
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GAMBA and its released benchmark code/data are distributed under the MIT
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license. Upstream annotation resources retain their original terms.
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functional-multiclass-gamba-100bp-noncoding-added.parquet
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version https://git-lfs.github.com/spec/v1
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oid sha256:a8d7e887c061262291dece2553c37994a48a84aad0e23b942817a3f345bb41c2
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size 41129016
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functional-multiclass-gamba-100bp.parquet
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version https://git-lfs.github.com/spec/v1
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oid sha256:541bda865687472aa4ec873d6c6cf4ff4c8331c655626407c42259b385597552
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size 36594002
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functional-multiclass-gamba-full-noncoding-added.parquet
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version https://git-lfs.github.com/spec/v1
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oid sha256:b74123101d4875c6770dd797de7768e346354a19eccdb65b07a3ebd32f97ddc3
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size 58468235
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functional-multiclass-gamba-full.parquet
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version https://git-lfs.github.com/spec/v1
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size 53649684
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