Publish reviewed GAMBA evaluation dataset
Browse files- README.md +105 -0
- functional-random-gamba-noncoding-added.parquet +3 -0
- functional-random-gamba.parquet +3 -0
README.md
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---
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pretty_name: "GAMBA Functional Regions: Feature vs Random"
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license: mit
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tags:
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- biology
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- genomics
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- dna
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- genome-language-model
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- benchmark
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- functional-genomics
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- hg38
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- parquet
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configs:
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- config_name: canonical
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data_files:
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- split: all
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path: functional-random-gamba.parquet
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- config_name: noncoding-added
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data_files:
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- split: all
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path: functional-random-gamba-noncoding-added.parquet
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---
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# GAMBA Functional Regions: Feature vs Random
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This dataset packages GAMBA's binary functional-region benchmark comparing
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annotated genomic features with chromosome- and length-matched random
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controls. Random controls avoid retained anchors from the same functional
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category.
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## Configs
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| Config | Train rows | Test rows | Total |
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|---|---:|---:|---:|
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| `canonical` | 135,692 | 33,982 | 169,674 |
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| `noncoding-added` | 150,726 | 37,834 | 188,560 |
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The `noncoding-added` config is an explicit extension from
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[Gamba-Processing](https://github.com/TaykhoomDalal/Gamba-Processing), not an
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additional category emitted by GAMBA's current `create_eval_data.py`.
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## Loading
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```python
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from datasets import load_dataset
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canonical = load_dataset(
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"Taykhoom/functional-random-gamba",
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"canonical",
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split="all",
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)
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train = canonical.filter(lambda row: row["split"] == "train")
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test = canonical.filter(lambda row: row["split"] == "test")
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```
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## Columns
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| Column | Description |
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|---|---|
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| `split`, `label` | Probe/fine-tuning `train` or held-out `test`; labels are `feature` or `random`. |
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| `sequence` | Strand-oriented GAMBA context of at most 2,048 bp. |
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| `pair_id` | Shared identifier for a feature and its matched random control. |
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| `category`, `scope` | Functional class and pooling scope. |
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| `chrom`, `start`, `end`, `strand` | Zero-based, half-open hg38 feature/control coordinates. |
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| `context_start`, `context_end` | Forward-genome coordinates of `sequence`. |
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| `roi_start`, `roi_end` | Feature/control offsets within `sequence`. |
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| `pool_start`, `pool_end` | Offsets to pool for representation evaluation. |
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| `name` | Source annotation name. |
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## Data source and processing
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The processing code reproduces the ten-category BED output from
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[Microsoft GAMBA](https://github.com/microsoft/gamba) commit `e83984e`
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byte-for-byte, then freezes all GAMBA autosomes plus `chrX` in parquet.
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The GAMBA models were pretrained on the chromosomes marked `train`. The paper's
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zero-shot result used the frozen models on `chr2`, `chr3`, `chr16`, and
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`chr22`, which are marked `test`; no task-specific model was fitted on these
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benchmark rows. Use only `test` to reproduce that paper subset. The `train`
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rows are provided for probing/fine-tuning or broader chromosome evaluation.
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## Citation
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Please cite the GAMBA paper:
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Consens, M. E. et al. *Predicting evolutionary rate as a pretraining task
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improves genome language model representations*. bioRxiv (2026).
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[doi:10.64898/2026.02.02.703275](https://doi.org/10.64898/2026.02.02.703275).
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A conference version is available on
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[OpenReview](https://openreview.net/forum?id=dkgM2ale4U).
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```bibtex
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@article{consens2026predicting,
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title = {Predicting evolutionary rate as a pretraining task improves genome language model representations},
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author = {Consens, Micaela Elisa and Yang, Kevin K. and Hall, Jimmy and Conard, Ashley Mae and Wang, Bo and Crawford, Lorin and Moses, Alan and Lu, Alex X.},
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journal = {bioRxiv},
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year = {2026},
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doi = {10.64898/2026.02.02.703275},
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url = {https://doi.org/10.64898/2026.02.02.703275}
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}
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```
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## License
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GAMBA and its released benchmark code/data are distributed under the MIT
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license. Upstream annotation resources retain their original terms.
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functional-random-gamba-noncoding-added.parquet
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version https://git-lfs.github.com/spec/v1
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oid sha256:432c44f2cc136857e94d930e656586b24bbdfc51adbbae842352619a4ba86f7c
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size 114035214
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functional-random-gamba.parquet
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version https://git-lfs.github.com/spec/v1
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oid sha256:167ea6587ae7645754310c33af55ccb60ba9251c07af87d992847f0cf2601b2b
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size 104692294
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