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19,443 results match your criteria H1N1 Influenza Swine Flu
Eur J Med Chem 2018 Dec 7;163:560-568. Epub 2018 Dec 7.
State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China. Electronic address:
It is urgently necessary to develop more effective anti-influenza agents due to the continuous emergence of drug-resistant strains of influenza virus. Our earlier studies have identified that certain pentacyclic triterpene derivatives are effective inhibitors of influenza virus infection. In the present study, a series of C-28 modified pentacyclic triterpene derivatives via conjugation with a series of polyphenols were synthesized, and their antiviral activities against influenza A/WSN/33 (H1N1) virus in MDCK (Madin-Darby canine kidney) cells were evaluated. Read More
Zoonoses Public Health 2018 Dec 14. Epub 2018 Dec 14.
Wildlife and Habitat Branch, BC Ministry of Forests, Lands, Natural Resource Operations and Rural Development, Nanaimo, British Columbia, Canada.
Striped skunks (skunks) are susceptible to respiratory infection by influenza A viruses (IAV). As they are common synanthropes, maintenance of IAV in skunks could provide a source of infection for humans. We previously studied the nasal turbinates, lungs and faeces of 50 free-ranging skunks for the presence of IAV and identified two individuals with influenza A(H1N1)pdm09 infection during the 2009/2010 and 2013/2014 flu seasons. Read More
Zoonoses Public Health 2018 Dec 14. Epub 2018 Dec 14.
Center of Excellences for Emerging and Re-emerging Infectious Diseases in Animals, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand.
Influenza A virus causes respiratory disease in both humans and animals. In this study, a survey of influenza A antibodies in domestic dogs and cats was conducted in 47 animal shelters in 19 provinces of Thailand from September 2011 to September 2014. One thousand and eleven serum samples were collected from 932 dogs and 79 cats. Read More
Adv Healthc Mater 2018 Dec 14:e1800953. Epub 2018 Dec 14.
Department of Chemical and Biomolecular Engineering, Yonsei University, Yonsei-ro 50, Seoul, 03722, Republic of Korea.
Powerful adjuvants to augment vaccine efficacy with a less immunogenic vaccine system are in great demand. In this study, a novel squalene-based cationic poly(amino acid) adjuvant (CASq) that elicits both cellular (Th1) and humoral (Th2) immune responses is developed. CASq is demonstrated to promote cellular uptake of viral antigen and stimulate macrophages, leading to active production of interleukin-12. Read More
Rev Med Virol 2018 Dec 12:e2024. Epub 2018 Dec 12.
Department of Bioinformatics and Biotechnology, International Islamic University, Islamabad, Pakistan.
Respiratory infections, especially those of the lower respiratory tract, remain a foremost cause of mortality and morbidity of children greater than 5 years in developing countries including Pakistan. Ignoring these acute-level infections may lead to complications. Particularly in Pakistan, respiratory infections account for 20% to 30% of all deaths of children. Read More
Proc Natl Acad Sci U S A 2018 Dec 12. Epub 2018 Dec 12.
Center for Sleep Sciences and Medicine, Stanford University School of Medicine, Palo Alto, CA 94304;
Type 1 narcolepsy (T1N) is caused by hypocretin/orexin (HCRT) neuronal loss. Association with the HLA DQB1*06:02/DQA1*01:02 (98% vs. 25%) heterodimer (DQ0602), T cell receptors (TCR) and other immune loci suggest autoimmunity but autoantigens are unknown. Read More
J Nephrol 2018 Dec 6. Epub 2018 Dec 6.
University of Insubria, Varese, Italy.
A significant interaction between kidneys and lungs has been shown in physiological and pathological conditions. The two organs can both be targets of the same systemic disease (eg., some vasculitides). Read More
Rev Paul Pediatr 2018 Oct-Dec;36(4):445-450
Universidade Federal de São Paulo, São Paulo, SP, Brasil.
Objective: To assess the prevalence and severity of wheezing in the first year of life of infants, using the standardized protocol of the Estudio Internacional de Sibilancias en Lactantes- phase 3, and compare the values obtained with those found in phase 1, conducted at the same center.
Methods: Between 2009 and 2010, parents and guardians of infants answered the written questionnaire of the Estudio Internacional de Sibilancias en Lactantes - phase 3, and its results were compared to those of phase 1, performed between 2005 and 2006. We divided the infants into wheezing and non-wheezing. Read More
Virusdisease 2018 Dec 26;29(4):553-559. Epub 2018 Sep 26.
2National Institute of Virology, Pune, Mahrashtra India.
Scant data exist about the epidemiology of influenza B in India. We set out to address the epidemiology of influenza B in a temperate region of northern India from 2010 to 2016. Outpatient and inpatient surveillance was conducted in patients presenting with acute respiratory infection in a northern Indian hospital from September 2010 till April 2016. Read More
Virusdisease 2018 Dec 20;29(4):548-552. Epub 2018 Oct 20.
1Department of Microbiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok Noi, Bangkok, Thailand.
Innate immune cells are key player in immune response to influenza virus infection. Influenza infected monocytes exacerbate the disease pathology. However, monocytes differ in susceptibilities to influenza virus infection. Read More
Virusdisease 2018 Dec 1;29(4):461-467. Epub 2018 Sep 1.
Department of Biological Science and Engineering, Maulana Azad National Institute of Technology, Bhopal, India.
Recently three FDA approved existing drugs, namely-Oseltamivir, Peramivir and Zanamivir, used against Neuraminidase (NA) for the inhibitory effect on the process of viral progeny release to inhibit infection. All NA subtypes has been divided into two groups (Group 1 and Group 2) based on phylogenetic study. Oseltamivir and Zanamivir drugs are designed for Group 2 NA but are also used against 2009 H1N1 NA that lies in Group 1. Read More
Influenza Other Respir Viruses 2018 Dec 9. Epub 2018 Dec 9.
Division of Infection Control and Environmental Health, Norwegian Institute of Public Health, 0213, Oslo, Norway.
Background: A population-based pregnancy cohort was established in Norway to study potential effects of exposure to the 2009 influenza pandemic or pandemic vaccination during pregnancy.
Objectives: We studied maternal A(H1N1)pdm09-specific hemagglutination inhibition (HI)-titer levels and waning in women with influenza-like illness (ILI) in pregnancy compared to vaccinated women. Moreover, we studied the association between HI-titers and self-reported severity and duration of ILI. Read More
Obstet Gynecol 2018 Dec 4. Epub 2018 Dec 4.
University of Florida College of Medicine & College of Public Health and Health Professions, Departments of Pediatrics and Epidemiology, Gainesville, Florida; and Emory University, Department of Gynecology and Obstetrics, Atlanta, Georgia.
The 2009 H1N1 pandemic demonstrated the severe effects of influenza illness on pregnant women. This experience stimulated efforts to improve influenza vaccination coverage among pregnant women and resulted in a substantial increase in coverage from less than 30% before 2009 to more than 50% a few years later. As memories fade of the pandemic year, influenza vaccination coverage has stagnated at around 50%, despite considerable information becoming available on strategies to improve vaccination coverage during pregnancy. Read More
Curr Opin Pediatr 2018 Dec 10. Epub 2018 Dec 10.
Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Purpose Of Review: Influenza causes a range of illnesses in children, from uncomplicated self-limited illness to severe disease and death. This review provides an update on the severity and burden of influenza in US children over recent seasons.
Recent Findings: The 2017-2018 influenza season was widespread and severe across all ages, including children. Read More
EBioMedicine 2018 Dec 5. Epub 2018 Dec 5.
Disease Biology Laboratory, Regional Centre for Biotechnology, National Capital Region Biotech Science Cluster, Faridabad, India. Electronic address:
Background: Activated platelets release cytokines/proteins including CXCL4 (PF4), CCL5 and fibrinopeptides, which regulate infection of several pathogenic viruses such as HIV, H1N1 and HCV in human. Since platelet activation is the hallmark of Dengue virus (DV) infection, we investigated the role of platelets in DV replication and also in a closely related Japanese Encephalitis virus (JEV).
Methods And Findings: Microscopy and PCR analysis revealed a 4-fold increase in DV replication in primary monocytes or monocytic THP-1 cells in vitro upon incubation with either DV-activated platelets or supernatant from DV-activated platelets. Read More
Am J Trop Med Hyg 2018 Dec 3. Epub 2018 Dec 3.
Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland.
Influenza transmission is increased among household contacts. Vaccination decreases transmission; however it is unclear how vaccinating a single individual alters disease risk among household contacts, particularly in regions with low vaccination coverage. Pregnant women were randomized to influenza or control vaccination. Read More
BMC Infect Dis 2018 Dec 7;18(1):637. Epub 2018 Dec 7.
School of Public Health and Community Medicine, Faculty of Medicine, UNSW Medicine, the University of New South Wales, Samuels Building, Room 209, Sydney, NSW, 2052, Australia.
Background: The aim of this study was to estimate the prevalence of pneumonia and secondary bacterial infections during the pandemic of influenza A(H1N1)pdm09.
Methods: A systematic review was conducted to identify relevant literature in which clinical outcomes of pandemic influenza A(H1N1)pdm09 infection were described. Published studies (between 01/01/2009 and 05/07/2012) describing cases of fatal or hospitalised A(H1N1)pdm09 and including data on bacterial testing or co-infection. Read More
PLoS One 2018 6;13(12):e0207918. Epub 2018 Dec 6.
Division of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
Background: Influenza and pneumonia are leading causes of morbidity and mortality among the elderly. Although vaccination is a main strategy to prevent these infectious diseases, concerns remain with respect to vaccine effectiveness.
Methods: During three influenza seasons (2014-2015, 2015-2016 and 2016-2017), we evaluated the effectiveness of the influenza and pneumococcal vaccines against pneumonia and acute exacerbation of cardiopulmonary diseases among the elderly aged ≥65 years with influenza-like illness (ILI). Read More
Arch Pharm (Weinheim) 2018 Dec 6. Epub 2018 Dec 6.
Fluoro and Agrochemicals Division (Organic Chemistry Division-II), CSIR - Indian Institute of Chemical Technology, Hyderabad, India.
Influenza remains a highly pathogenic and hardly controlled human infection. The ability of selecting drug-resistant variants necessitates the search and development of novel anti-influenza drugs. Herein, we describe the synthesis and evaluation of a series of novel 2-substituted 7,8-dihydro-6H-imidazo[2,1-b][1,3]benzothiazol-5-ones 3a-k for their virus-inhibiting activity against influenza A virus. Read More
Clin Infect Dis 2018 Dec 3. Epub 2018 Dec 3.
Canadian Center for Vaccinology, IWK Health Centre and Nova Scotia Health Authority, Dalhousie University, Halifax, Nova Scotia, CA.
Background: Recent studies have demonstrated the possibility of negative associations between prior influenza vaccines and subsequent influenza vaccine effectiveness (VE), depending on season and strain. We investigated this association over 4 consecutive influenza seasons (2011/2012-2014/2015) in Canada.
Methods: Using a matched test-negative design, laboratory-confirmed influenza cases and matched test-negative controls admitted to hospitals were enrolled. Read More
PLoS One 2018 3;13(12):e0208028. Epub 2018 Dec 3.
International Institutional Cooperation, Institut national de la santé et de la recherche médicale (INSERM), Paris, France.
Background And Aim: The majority of seasonal influenza vaccines are trivalent, containing two A virus strains (H1N1 and H3N2) and one B virus strain. The co-circulation of two distinct lineages of B viruses can lead to mismatch between the influenza B virus strain recommended for the trivalent seasonal vaccine and the circulating B virus. This has led some manufacturers to produce quadrivalent influenza vaccines containing one strain from each B lineage in addition to H1N1 and H3N2 strains. Read More
PLoS Pathog 2018 Dec 3;14(12):e1007417. Epub 2018 Dec 3.
Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Starkville, Mississippi State, Mississippi, United States of America.
Genetic reassortment between influenza A viruses (IAVs) facilitate emergence of pandemic strains, and swine are proposed as a "mixing vessel" for generating reassortants of avian and mammalian IAVs that could be of risk to mammals, including humans. However, how a transmissible reassortant emerges in swine are not well understood. Genomic analyses of 571 isolates recovered from nasal wash samples and respiratory tract tissues of a group of co-housed pigs (influenza-seronegative, avian H1N1 IAV-infected, and swine H3N2 IAV-infected pigs) identified 30 distinct genotypes of reassortants. Read More
IEEE Trans Ultrason Ferroelectr Freq Control 2018 Nov 30. Epub 2018 Nov 30.
This work presents fabrication of thermal-piezoresistive nanoelectromechanical (NEM) silicon disk resonators and their characterization as highly sensitive mass sensors. Forest of multiwall carbon nanotubes (MWCNT) has been grown on top surface of the fabricated devices increasing the resonator effective surface area, which in turn increases the adsorption capacity and therefore frequency shift of the sensor in molecular or particulate detection applications. To investigate the effect of the enhanced surface area on frequency shift, devices with and without MWCNTs were exposed to an aqueous solution of manganese sulfate for different deposition times and the resonance frequency shift was recorded accordingly. Read More
Scand J Immunol 2018 Dec 1:e12738. Epub 2018 Dec 1.
Institute of Beijing Brain Sciences, Beijing, 100850, China.
T cell immunoglobulin and mucin domain protein 3 (Tim-3) is an immune checkpoint inhibitor in T cells and innate immune cells. The deregulated upregulation of Tim-3 is related to immune exhaustion in tumor and viral infection. To overcome Tim-3-mediated immune tolerance, we developed a novel monoclonal antibody against human Tim-3 (L3G) and investigated its roles in inhibiting Tim-3 signaling and overcoming immune tolerance in T cells and monocytes/macrophages. Read More
J Educ Health Promot 2018 29;7:129. Epub 2018 Oct 29.
Department of Community Medicine, Seth G. S. Medical College and KEM Hospital, Mumbai, Maharashtra, India.
Introduction: Immunization against vaccine-preventable diseases in adults is the need of the hour. The student nurses by virtue of training are the frontline health workers dealing with patient care. They are exposed to maximum risk of contracting the diseases. Read More
Sci Rep 2018 Nov 30;8(1):17476. Epub 2018 Nov 30.
Emerging Infectious Diseases Programme, Duke-NUS Medical School, Singapore, Singapore.
As a leading global city with a high population density, Singapore is at risk for the introduction of novel biological threats. This risk has been recently reinforced by human epidemics in Singapore of SARS coronavirus, 2009 pandemic H1N1 influenza A virus, and enterovirus 71. Other major threats to Singapore include MERS-coronavirus and various avian and swine influenza viruses. Read More
J Nutr 2018 Dec;148(12):1968-1975
Global Health Center, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
Background: In the growing embryo, the vitamin A requirement is tightly regulated. Maternal vitamin A deficiency during pregnancy may alter maternal immune function to accommodate the fetus.
Objective: Our primary objective was to determine the effect of oral vitamin A supplementation (VAS) during pregnancy and until 6 mo postpartum on pandemic H1N1-vaccine responses in mothers and their infants at 6 mo of age. Read More
Influenza Other Respir Viruses 2018 Dec 4. Epub 2018 Dec 4.
Leidos Biomedical Research Inc. in support of National Institute of Allergy and Infectious Diseases, Bethesda, Maryland.
Background: The relationship between obesity and risk of complications described during the 2009 influenza pandemic is poorly defined for seasonal influenza and other viral causes of influenza-like illness (ILI).
Methods: An observational cohort of hospitalized and outpatient participants with ILI was conducted in six hospitals in Mexico. Nasopharyngeal swabs were tested for influenza and other common respiratory pathogens. Read More
Evid Based Complement Alternat Med 2018 1;2018:2606583. Epub 2018 Nov 1.
Department of Food and Nutrition, Duksung Women's University, Seoul 01369, Republic of Korea.
Antiviral activities of (MA) juice and seed were examined using time-of-addition plaque assays against influenza viruses, A/Brisbane/59/2007 (H1N1) (BR59), pandemic A/Korea/01/2009(H1N1) (KR01), A/Brisbane/10/2007(H3N2) (BR10), and B/Florida/4/2006 (FL04). MA juice (MAJ) showed much higher antiviral activity than MA seed (MAS). In the pre- and cotreatment of virus, MAJ showed antiviral effects against BR59, KR01, and FL04 in a dose-dependent manner. Read More
Euro Surveill 2018 Nov;23(48)
ORS PACA, Observatoire Régional de la Santé Provence-Alpes-Côte d'Azur, Marseille, France.
Background and aimsSeasonal influenza vaccination (SIV) uptake (SIVU) rates in France are below target. We (i) describe trends in French SIVU over 10 consecutive seasons among different target groups and (ii) examine the effects of the 2009 influenza A(H1N1) pandemic and the publication of new SIV recommendations in 2011 and 2013.MethodsOur study was based on records of vaccines delivered in community pharmacies for a permanent, representative sample of 805,000 beneficiaries of the French National Health Insurance Fund. Read More
NPJ Vaccines 2018 29;3:55. Epub 2018 Nov 29.
1VIB-UGent Center for Medical Biotechnology, VIB, 9052 Ghent, Belgium.
Split inactivated influenza vaccines remain one of the primary preventative strategies against severe influenza disease in the population. However, current vaccines are only effective against a limited number of matched strains. The need for broadly protective vaccines is acute due to the high mutational rate of influenza viruses and multiple strain variants in circulation at any one time. Read More
Int J Microbiol 2018 28;2018:8945142. Epub 2018 Oct 28.
Central Department of Microbiology, Tribhuvan University, Kirtipur, Nepal.
Acute respiratory infections (ARIs) are one of the major public health problems in developing countries like Nepal. Besides the influenza, several other pathogens are responsible for acute respiratory infection in children. Etiology of infections is poorly characterized at the course of clinical management, and hence empirical antimicrobial agents are used. Read More
3 Biotech 2018 Dec 20;8(12):492. Epub 2018 Nov 20.
1Department of Biotechnology, Thapar Institute of Engineering and Technology, 147004 Patiala, India.
In the current study, two highly conserved (> 90%) H1N1 hemagglutinin peptides STDTVDTVLEKNVTVTHSVNL (H1) and KVNSVIEKMNTQFTAVGKEF (H2) containing multiple T-cell epitopes have been assessed for their immunogenic potential in vitro, subjecting peripheral blood mononuclear cells from healthy volunteers to repetitive stimulation of chemically synthesised H1 and H2 peptides, and measuring their interferon (IFN)-γ level (ELISA) and proliferation (MTT assay). Further, these peptides were analysed for their binding affinity with 18 different human leukocyte antigen (HLA) class I and II by means of molecular docking. All seven samples tested for H1- and H2-induced IFN-γ secretion were found to have enhanced IFN-γ production. Read More
Mucosal Immunol 2018 Nov 29. Epub 2018 Nov 29.
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, MI, 48109, USA.
Post influenza bacterial pneumonia is associated with significant mortality and morbidity. Dendritic cells (DCs) play a crucial role in host defense against bacterial pneumonia, but their contribution to post influenza-susceptibility to secondary bacterial pneumonia is incompletely understood. WT and CCR2 mice were infected with 100 plaque forming units (pfu) H1N1 intranasally alone or were challenged on day 5 with 7 × 10 colony forming units (cfu) methicillin-resistant Staphylococcus aureus intratracheally. Read More
EMBO Mol Med 2018 Nov 28. Epub 2018 Nov 28.
State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Pokfulam, Hong Kong
Glycine decarboxylase (GLDC) was prioritized as a candidate susceptibility gene to severe influenza in humans. The higher expression of GLDC derived from genetic variations may confer a higher risk to H7N9 and severe H1N1 infection. We sought to characterize GLDC as functional susceptibility gene that GLDC may intrinsically regulate antiviral response, thereby impacting viral replication and disease outcome. Read More
Influenza Other Respir Viruses 2018 Nov 28. Epub 2018 Nov 28.
Pediatrics and Medicine, Emory University School of Medicine, 2015 Uppergate Drive, 30322, Atlanta, Georgia, United States.
Ninety-five adults enrolled in the Etiology of Pneumonia in the Community study with negative admission influenza polymerase chain reaction (PCR) tests received influenza vaccination during hospitalization. Acute and convalescent influenza serology were performed. After vaccination, seropositive (≥1:40) hemagglutination antibody titers (HAI) were achieved in 55% to influenza A(H1N1)pdm09, 58% to influenza A(H3N2), 77% to influenza B (Victoria), and 74% to influenza B (Yamagata) viruses. Read More
Mol Med Rep 2018 Nov 26. Epub 2018 Nov 26.
Institute of Chinese Integrative Medicine, Guangzhou Medical University, Guangzhou, Guangdong 511436, P.R. China.
Eucommia ulmoides Oliver (Du-Zhong) is an ancient Chinese herbal remedy used for the treatment of various diseases. To date, the effects of its constituent lignans on influenza viruses remain to be elucidated. In the present study, a lignan glycoside was isolated and purified from Eucommia ulmoides Oliver. Read More
Emerg Microbes Infect 2018 Nov 28;7(1):194. Epub 2018 Nov 28.
Poultry Diagnostic and Research Center, College of Veterinary Medicine, University of Georgia, 953 College Station Rd, Athens, GA, 30602, USA.
Wild aquatic birds are the major reservoir of influenza A virus. Cloacal swabs and feces samples (n = 6595) were collected from 62 bird species in Argentina from 2006 to 2016 and screened for influenza A virus. Full genome sequencing of 15 influenza isolates from 6 waterfowl species revealed subtypes combinations that were previously described in South America (H1N1, H4N2, H4N6 (n = 3), H5N3, H6N2 (n = 4), and H10N7 (n = 2)), and new ones not previously identified in the region (H4N8, H7N7 and H7N9). Read More
Global Health 2018 11 27;14(1):117. Epub 2018 Nov 27.
Accident and Emergency Medicine Academic Unit, The Chinese University of Hong Kong, Trauma & Emergency Centre, Prince of Wales Hospital, Shatin, New Territories, Hong Kong.
Background: The global travel and tourism industry has been rapidly expanding in the past decades. The traditional focus on border screening, and by airline and cruise industries may be inadequate due to the incubation period of an infectious disease. This case study highlights the potential role of the hotel industry in epidemic preparedness and response. Read More
Biochemistry (Mosc) 2018 Nov;83(11):1411-1421
Lomonosov Moscow State University, Belozersky Research Institute of Physico-Chemical Biology, Moscow, 119991, Russia.
Influenza A virus nuclear export protein (NEP) plays an important role in the viral life cycle. Recombinant NEP proteins containing (His)-tag at either N- or C-terminus were obtained by heterologous expression in Escherichia coli cells and their high propensity for aggregation was demonstrated. Dynamic light scattering technique was used to study the kinetics and properties of NEP aggregation in solutions under different conditions (pH, ionic strength, presence of low-molecular-weight additives and organic solvents). Read More
Clin Infect Dis 2018 Nov 27. Epub 2018 Nov 27.
Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, MD.
Introduction: We evaluated Russian-backbone, live-attenuated influenza vaccine (LAIV) for immunogenicity and viral shedding in a phase 2, randomized, placebo-controlled trial among Bangladeshi children.
Materials And Methods: Healthy children received a single, intranasal dose of LAIV containing the 2011-2012 WHO recommended formulation or placebo (clinicaltrials.gov # NCT01625689). Read More
ERJ Open Res 2018 Oct 23;4(4). Epub 2018 Nov 23.
Unit of Airway Inflammation, Lund University, Lund, Sweden.
Viral infections predispose to the development of childhood asthma, a disease associated with increased lung mast cells (MCs). This study investigated whether viral lower respiratory tract infections (LRTIs) can already evoke a MC response during childhood. Lung tissue from young children who died following LRTIs were processed for immunohistochemical identification of MCs. Read More
J Vasc Surg Venous Lymphat Disord 2018 Nov 23. Epub 2018 Nov 23.
Acute Care Surgery, Department of Surgery, University of Michigan, Ann Arbor, Mich. Electronic address:
Background: An association between increased venous thromboembolism (VTE) events and influenza A H1N1 (H1N1) was noted in the first 10 patients with severe acute respiratory distress syndrome (ARDS). An empirical systemic anticoagulation protocol (heparin intravenous infusion) was initiated when autopsy of patients with severe hypoxemia confirmed multiple primary pulmonary thrombi and emboli. The purpose of this study was to examine the relationship between H1N1 and VTE events and to assess the efficacy of empirical systemic heparin anticoagulation in preventing VTE and death in H1N1 severe ARDS patients. Read More
Acta Virol 2018 ;62(4):401-408
Hypothiocyanite (OSCN-) is a natural component of human saliva and is produced by the lactoperoxidase (LPO)/thiocyanate/hydrogen peroxide (H2O2) system. OSCN- has been previously shown to exhibit antiviral activity against influenza viruses (IFV) A/H1N1/2009 and A/H1N2/2009 in vitro as well as antimicrobial and antifungal activities. We elucidated the antiviral activity of OSCN- against both IFV types A and B and the mode of its antiviral action. Read More
Wellcome Open Res 2018 23;3:49. Epub 2018 Jul 23.
Medical Research Council Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Antibodies against pathogens provide information on exposure to infectious agents and are meaningful measures of past and present infection. Antibodies were measured in the plasma of children that are the offspring in a population-based birth cohort, the Avon Longitudinal Study of Parents and Children (ALSPAC). Plasma was collected during clinics at age 5, 7, 11 and 15 years. Read More
Antivir Chem Chemother 2018 Jan-Dec;26:2040206618811416
3 Farmak Public Joint Stock Company, Kiev, Ukraine.
Aims: New therapeutics for the control of influenza virus infections are needed to alleviate the burden caused by seasonal epidemics and occasional pandemics, and to overcome the potential risk of drug-resistance emergence. Enisamium iodide (Amizon®, Farmak) is currently approved for clinical use for the treatment of influenza in 11 countries which includes Ukraine, Russia, Belarus, Kazakhstan, and Uzbekistan. However, experimental evidence of the antiviral activity of enisamium has not been reported. Read More
J Feline Med Surg 2018 Nov 22:1098612X18813248. Epub 2018 Nov 22.
1 Sydney School of Veterinary Science, The University of Sydney, Camden, Australia.
Objectives: The aim of this study was to conduct a comprehensive assessment of feline infectious upper respiratory tract infection (URTI) and disease (URTD) in Australian cats.
Methods: Laboratory data demonstrating URTI from feline URTD multiplex PCR panel (feline Herpesvirus 1 [FHV-1], feline calicivirus [FCV], Bordetella bronchiseptica, Chlamydophila felis, Mycoplasma felis and H1N1 influenza) submissions in Australia (2013-2015) were obtained. For comparison, reports of feline URTD during the same time period were sourced from a voluntary companion animal disease surveillance system. Read More
Front Cell Infect Microbiol 2018 6;8:386. Epub 2018 Nov 6.
Key Laboratory of Animal Epidemiology of Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing, China.
The inflammatory response and apoptosis have been proved to have a crucial role in the pathogenesis of the influenza A virus (IAV). Previous studies indicated that while IAV commonly causes pancreatitis and pancreatic damage in naturally and experimentally infected animals, the molecular mechanisms of the pathogenesis of IAV infection are less reported. In the present study, we showed for the first time that both avian-like (α-2,3-linked) and human-like (α-2,6-linked) sialic acid (SA) receptors were expressed by the mouse pancreatic cancer cell line PAN02 and the human pancreatic cancer cell line PANC-1. Read More
Front Microbiol 2018 6;9:2643. Epub 2018 Nov 6.
Shanghai Public Health Clinical Center and School of Basic Medical Sciences, Key Laboratory of Medical Molecular Virology of MOE/MOH, Fudan University, Shanghai, China.
Influenza A viruses (IAV) comprise some of the most common infectious pathogens in humans, and they cause significant mortality and morbidity in immunocompromised people as well as children and the elderly. After screening an FDA-approved drug library containing 1280 compounds by cytopathic effect (CPE) reduction assay using the Cell Counting Kit-8, we found two antihistamines, carbinoxamine maleate (CAM) and S-(+)-chlorpheniramine maleate (SCM) with potent antiviral activity against A/Shanghai/4664T/2013(H7N9) infection with IC (half-maximal inhibitory concentration) of 3.56 and 11. Read More
Paediatr Child Health 2018 Sep 5;23(6):e95-e101. Epub 2018 Mar 5.
Division of Respiratory Medicine, Hospital for Sick Children, Toronto, Ontario.
Aim: Narcolepsy, encompassing excessive daytime sleepiness (EDS), cataplexy, sleep paralysis and hypnogogic hallucinations, was previously considered rare in childhood. Recently, cases of childhood narcolepsy have increased significantly and the reasons for this may include the increasing awareness of narcolepsy as well as the H1N1 vaccination. The aim of this study was to describe the clinical characteristics of childhood narcolepsy, specifically focusing on cataplexy subtypes that may facilitate early recognition of narcolepsy. Read More

domain: literature


text:
Talking about Noor Inayat Khan, played by Radhika Apte in A Call to Spy:
Rajyasree: One of her parents was Indian andshe was a pacifist. So all those things...
Abhinandan: She was a what?
Rajyasree: A pacifist. She doesn’t believe in… a, like a baby pacifier, but a pacifist.
Abhinandan: Ok, who believes in Pacific Ocean?
Rajyasree:Haa like she used to swim in the Pacific Ocean, so she was a pacifist.
Abhinandan: She was deep. I’m more of an Atlantist.
Rajyasree: Yeah, I’m also someone known as an Atlantist you know.
Abhinandan: You’re a bloody Hoogliest. Which is dirty and full of fish!
Rajyasree and Abhinandan burst out laughing.
This and a whole lot of other stuff awful and awesome as Abhinandan Sekhri and Rajyasree Sen discuss the historical drama A Call to Spy; David Fincher’s Mank; Amazon series The Wilds; Pakistani animated short film Swipe; and Smiths City’s whiteware commercial.
00:01 - Introduction
1:29 - A Call to Spy
12:10 - Mank
28:50 - Letters from listeners
37:28 - The Wilds
47:46 - Letters from listeners
51:09 - Swipe
56:25 - Letters from listeners
1:01:27 - Smiths City ad
Recorded and produced by Jude Weston, edited by Umrav Singh.

domain: artistic


Before dawn on the morning of September 15, 1916, a deep rumble suddenly shook the French countryside as the British launched a major offensive to capture the village of Courcelette. Waves of British soldiers vaulted over the top of their trenches accompanied by something that no German soldier—nor any soldier in battle, for that matter—had ever seen. For rising out of the mud and the darkness came a fleet of strange mechanical beasts creeping forward on conveyor-belt-like tracks wrapped around their wheels.
The British military hoped that its new weapon—the tank—could finally break the deadly impasse of the Battle of the Somme. Early in the war, British Army Colonel Ernest Swinton proposed the development of an armored vehicle that could traverse difficult terrain, and First Lord of the Admiralty Winston Churchill approved the development of the so-called “landships” in early 1915. Much of the design work was done by two men working secretly inside a Lincoln, England, hotel room near a threshing machine manufacturer commissioned to build the prototypes.
The first prototype, “Little Willie,” was tested in September 1915 to poor results. A second prototype, “Big Willie,” achieved much greater success and was deemed ready for battle. Swinton formed the Heavy Section of the Machine Gun Corps in March 1916 to train 500 recruits to operate the vehicles. Production workers noted that the oddly-shaped shells of the vehicles resembled water tanks, and they were secretly shipped to the front lines in crates labeled “tanks.” The name stuck.
Desperate to end the stalemate of the Battle of the Somme, the British rushed the new weapon into battle. The tanks lacked sufficient testing and their crews ample training. Tank crews had never trained with infantry units for this new type of warfare, and some had never even fired practice rounds from their guns. Of the 49 Mark I tanks sent to the battlefield, 17 were sidelined by mechanical malfunctions even before the offensive on Courcelette could begin.
While the 32 tanks sent into battle mowed down barbed wire, many struggled to cross the trenches and artillery craters in no-man’s land. Some were forced to be ditched in the broken ground. The new instrument of war, which moved at a walking pace of fewer than 4 miles per hour, proved too slow to hold positions during counterattacks.
The eight-man crews, including two drivers, who squeezed inside the tanks sweated through insufferable heat and were forced to communicate with hand signals thanks to the engine’s deafening din. They were alarmed to discover that the skin of the 29-ton machine also offered less protection than they had hoped. While some German troops, not knowing what to do against these unfamiliar terrestrial ironclads, ran away, others unleashed machine gun and pistol fire, grenades and artillery at the tanks. A barrage of bullets pierced the tanks’ armor, and scalding metal shards sprayed the crews like shrapnel, burning their hands and faces.
“We steamed ahead, squashing dead Germans as we went,” reported tank commander Lieutenant Basil Henriques of his vehicle’s progress. “As we approached the German line they let fire at us with might and main. At first no damage was done and we retaliated, killing about 20. Then a smash against my flap at the front caused splinters to come in and the blood to pour down my face. Another minute and my driver got the same.”
Armed with either 6-pounder cannons or machine guns, the primitive tanks failed to break the military deadlock of the Battle of the Somme. Only 9 tanks reached enemy territory, and only 3 returned to British lines, all too badly damaged to ever see action again. Nevertheless, British military leaders saw the potential of the new war machines. British Commander-in-Chief Sir Douglas Haig ordered the production of hundreds more.
“The tanks had limited success on that first day in military terms, however their success in terms of psychology shouldn’t be underestimated,” David Willey, curator of The Tank Museum in Bovington, England, told the BBC. “The German troops were terrified of these machines and for the British, the tanks were a huge morale boost. This was a British invention, designed to save soldiers’ lives, and it gave people hope, both on the front line and back at home.”
The Mark I was remodeled several times before war’s end, and better-designed British tanks proved decisive at the Battle of Cambrai in November 1917. Before the end of World War I, German tanks—some of them restored versions of captured British tanks—also took to the battlefield. The tank would come to dominate 20th-century warfare, particularly during World War II when Nazi Panzer divisions used them to devastating effect on Blitzkrieg attacks across Europe.


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Manchester Personal Trainer Ollie Lawrence says the simple answer is yes, carbs are the main body’s source of energy, so we do need them as the body needs energy. As human beings we need more balanced healthier diets that contain all food groups.
You will hear everybody talking about cutting carbohydrates out of their diet for losing weight, this is not the right way to do it and here at Ollie Lawrence Personal Trainer Manchester we explain that weight loss is all about what time of day we eat certain foods compared to the type of food group.
Now for the science..
There are only 3 food groups and everything you eat fall into these 3 categories. These good groups are Carbohydrates, fats and protein… a lot of people think that sugar is a food group on it’s own, however sugar is a carbohydrate along with starch and fibre. Sugars are the most harmful carbs to take on board when looking to lose weight, not only will you gain weight when taking on excess sugar but you will also have problems with your body’s insulin levels spiking and causing more serious problems with blood sugar levels and furthermore in serious cases, diabetes.
Carbs are the body’s first source of energy, (hence carb loading for many athletes in their diets before an event/competition) and the body will burn up carbohydrate stores in the body as energy before any of the other 2 food groups. In the average human being their is about 72 hours worth of carbs stored to covert to energy, so therefore if you didn’t eat anything for 72 hours and just trained and kept going your body would just burn all of your carbs stores.
Next your body uses Fats as a source of energy, again in the average human being there is around 24 hours worth of fats for your body to burn before your body touches their protein stores. Essentially if you didn’t touch a thing to eat for 4 days your body would burn all of your body’s excess carbohydrates store and furthermore your fats stores and convert them to energy to keep your body and internal organs working.
So the science behind people saying cut out all carbs and you’ll lose weight is that when you do that, you now know that after 72 hours of not eating carbs, your body would of converted them all to energy. Furthermore you also know after that initial 72 hours without any carbs that your body will automatically start using up fat stores to convert to energy and keep you alive. Thus you will then lose fat as your body is converting it for energy to keep you alive.
As previously stated carbohydrates are the body’s first source of energy and they are converted to keep you alive and all of your internal organs working. Any excess carbs are stored as fat on the body and not converted as energy, especially late at night! This is the most common problem with people in modern life, carbs are in more or less everything you eat including vegetables, fruits and eggs. The only way you could eat a ‘carb’ free diet is to only eat meat (protein) and drink water.
If you lead a lifestyle like most, where your working in the day and sleeping at night, then your body will need carbs as a source of energy first thing in the morning.
As you go throughout the day your body is converting everything you eat to energy or storing food as fat (if your body doesn’t need it). Your body naturally becomes more tired towards night time as your body wants to shut down and go to sleep as it’s tired from the days activities. If you eat carbohydrates late at night and your body doesn’t need them (it’s ready to shut down and doesn’t want energy) it won’t convert them to energy, but store them as fat.
So eating carbs such as biscuits, chocolates, alcohol and high sugary deserts late at night is a big no no , however many people seem to make these mistakes. A better option for dinner/tea would be protein (meat) with green (alkaline) vegetables. Filling up on meat and green vegetables is ideal rather than eating rice or pasta late at night where your body will store those foods as fat as they are excess carbs.
Remember you are what you eat!

domain: biology


As of October 23rd, 2017, Council has adopted the revised Brookswood-Fernridge Community Plan after it passed 3rd reading.
The residents have been heavily involved in the creation/reviewing process since the Council initiated the planning process in 2016. With a finalized community plan in place, more certainty is created for developers by defining future land uses and requirements for proposed projects.
Just like any community plan, the next step in the process is to define the individual neighbourhood plans which are speculated to be completed in 2018. The community plan has been separated into 4 proposed NCP's; Booth, Fernridge, Rinn and Glenwood, with all but the latter being slated for planning immediately. Before any further planning is discussed, an in-depth environmental and topographical study will be completed in order to protect Brookswood's abundant natural resources and ecosystems. For many residents in Brookswood, maintaining the treasured landscape is a huge concern as development nears. Studies such as these are seen as a huge win for those who so strongly opposed the plan.
VIEW THE AMENDED BROOKSWOOD-FERNRIDGE COMMUNITY PLAN HERE:
Source: Township of Langley


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28 January 2003 :
The influence of acute hypercapnia on the quantity and oxidative metabolism of bronchoalveolar lavage-derived leukocytes in the mechanically ventilated rabbit.
Med Sci Monit 2003; 9(1): BR8-15 :: ID: 4790
08 Mar 2014 : Research paper
The pleth variability index as an indicator of the central extracellular fluid volume in mechanically ventilated patients after anesthesia induction: Comparison with initial distribution volume of glucose
Wenqing Lu, Jing Dong
Med Sci Monit 2014; 20:386-392
16 Feb 2017 : Clinical Research
Effect of Mild Hypercapnia on Lung Oxygenation in Sitting Position During Shoulder Arthroscopy Under General Anesthesia
Hyun Jeong Kwak, Ji Yeon Lee
Med Sci Monit 2017; 23:843-849
29 Apr 2013 : Case report
Bijar Ghafouri, Lennart H. Persson
Am J Case Rep 2013; 14:129-133
01 Aug 2008
Niemann-Pick disease type C2 presenting as fatal pulmonary alveolar lipoproteinosis: morphological findings in lung and nervous tissue
Björn Bjurulf, Signe Spetalen
Med Sci Monit 2008; 14(8): CS71-75
19 Jun 2018 : Clinical Research
Sabine Zirlik, Markus Friedrich Neurath
Med Sci Monit 2018; 24: CLR4198-4203
01 September 2023 : EditorialEditorial: A Rapid Global Increase in COVID-19 is Due to the Emergence of the EG.5 (Eris) Subvariant of Omicron SARS-CoV-2
Med Sci Monit 2023; 29:e942244
22 Sep 2023 : Clinical ResearchComparative Analysis of Symptomatology in Hospitalized Children with RSV, COVID-19, and Influenza Infections
Med Sci Monit In Press; DOI: 10.12659/MSM.941229
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Med Sci Monit 2022; 28:e936292

domain: library


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Putin praises Army-2017 international military forumMilitary & Defense August 22, 14:15
Belarus invites Ukraine and NATO to monitor West-2017 military drillsMilitary & Defense August 22, 13:55
Russia may develop seven-tonne remote-controlled convertiplaneMilitary & Defense August 22, 13:53
Deliveries of Mi-28NM helicopters may start in 2018Military & Defense August 22, 13:39
Press review: US Embassy's seismic visa shift and Iraq mops up Islamic StatePress Review August 22, 13:00
Russia to grant $700 mln loan to BelarusBusiness & Economy August 22, 12:58
Russia’s Aerospace Force to get eight Mi-28UB helicopters by year-endMilitary & Defense August 22, 12:44
Ka-52 helicopter to be armed with new defense systemMilitary & Defense August 22, 12:00
Rostov-on-Don inferno claims life of one victimSociety & Culture August 22, 11:41
"I think it will take one or two years to determine the status of southeastern territories of Ukraine. It will be a period when sanctions will remain in force,” he said.
However, he expects no stronger measures to be imposed.
The West announced new sectoral sanctions against Russia in late July over Moscow’s position on Ukrainian events, in particular, what the West claimed was Moscow’s alleged involvement in mass protests in Ukraine’s war-torn southeast.
In response, Russia imposed on August 6 a one-year ban on imports of beef, pork, poultry, fish, cheeses, fruit, vegetables and dairy products from Australia, Canada, the EU, the United States and Norway.

domain: politics


There is nowhere I have visited in the UK that’s friendlier than Sheffield.
As you explore the streets and look around shops, you find yourself drawn into conversation.
Even when I walked into the Costa, it was so different from the vibe you get in London.Forget Paris – your next romantic weekend break is in Surrey
Gone were the haggard, miserable faces staring down at their phones until they could rush out of the shop clutching a coffee cup – instead, I got smiles, ‘hiya love’ and friendly conversation.
It was quite a shock to the system – but one I welcomed.
After a weekend spent driving through the Peak District and enjoying a drink while looking out over the city, I found myself returning home with the knowledge that a place existed where not only were the people actually cheerful – but I could get a bacon sandwich for under £2. Result.
The Forum, located in the heart of Sheffield city centre, knows a thing or two about gin.
If you’re looking for a fresh take on this beverage, you’ll find yourself spoilt for choice.
The standard Hendricks and Bombay Sapphire options are available – but those willing to step outside their comfort zone can go for the Manchester Raspberry Infused Gin, with almond, dandelion, burdock root and fresh raspberries.
Nordes Galician Gin is infused with eucalyptus, hibiscus, liquorice and tea, Warner Edwards Victoria’s Rhubarb is blended with hand-pressed rhubarb juice, and Jinzu features cherry blossom and Japanese sake.
As if that wasn’t enough, True North Brew Co, the people behind this gin heaven, run the Sheffield School of Gin, where students can learn about the history of gin, create their own blend using flavours of their choice and take the 50cl bottle home.
The three-hour sessions are intimate – no more than eight guests attend a single session, and you’ll be paired with people who are similarly enthusiastic about gin.
The Slice Bar is open every day, from 4pm until late.
Italian sourdough pizza is served by the slice – with a growing range of craft beer available to go with it.
If you’re not sure which beer to go for, the staff are on hand to recommend which will go best with your pizza.
For example, you may like to pair the Cheesy-E – a classic Italian pizza – with Five Points Pale, a light and fragrant vegan beer.
If you have a heavy night out in Sheffield, The Green Room is a good place to go for breakfast the next morning – their bacon butty was under £2 and delivered promptly with a steaming mug of tea.
For those who don’t feel up to venturing out for their food, opt for a stay at the Leopold Hotel Sheffield, which offers an award-winning breakfast.
The pubs and bars
Those looking for an extravagant drink will enjoy spending a few hours in Kettle Black, a bar which offers a range of elegant cocktails.
The espresso is shaken with Ketel One vodka, Kahlua and sugar syrup, which is the option my friend went for.
I chose the Lemon Meringue, which was mixed with Absolut Vanilla, Limoncello, fresh lemon juice, milk, cream and vanilla syrup.
For a more laid-back vibe, The Green Room offers comfortable seating, decent background music and reasonably priced food.
It’s somehow always open – I rocked up at 8am one morning, then came back at 11pm, and it was still going.
Whether you want to chill on a sofa in the morning with a cup of tea or head back for some drinks and live music in the evening, The Green Room is the place to be.
The street art
Everywhere you go in Sheffield, you’ll find street art, graffiti and wall murals.
Whether it’s on the side of a pub, a derelict building or a shop shutter, artists will find a way to make their mark.
The vegan quarter
Sheffield has a fairly new vegan quarter – there are four vegan-run establishments within 10 minutes’ walk of each other.
Burgerlolz is a 100% vegan eatery, offering ‘kick-ass burgers with a twist’.
Vegans who want to get some food shopping done can visit The Incredible Nutshell – Sheffield’s first and only 100% vegan grocery shop.
Make No Bones is another place for vegans to get some food while they’re out and about.
The 100% vegan eatery offers a range of dishes for those who want a small and cosy venue to eat in.
The White Lion is a vegan-run pub, serving vegan real ale, cider and lager – the perfect place to end your day in.
The live music scene
The Leadmill is a former flour mill that’s now a live music venue.
It first opened its doors in 1980 and has seen performances from acts such as Pulp, Manic Street Preachers, Coldplay, Muse, The Stereophonics and The White Stripes.
The venue is so renowned that Franz Ferdinand once told Arcade Fire that playing the Leadmill was seen as a ‘rite of passage’.
If you’re into a more alternative vibe, try out the Lughole – the venue describes itself as ‘run by the punks, for the punks’.
The Peak District
The Peak District is a picturesque area at the southern end of the Pennines, a mountain range in northern England.
It’s split into the Dark Peak, where you’ll find moorland, and the White Peak, where the geology is mainly limestone.
Sheffield is an ideal place to go for a drive and explore the countryside.
Take a seat outside at The Norfolk Arms and enjoy a drink while you look out at the beautiful scenery and soak up the relaxed atmosphere.
Where to stay
I stayed at the Leopold Hotel, an elegant building in the heart of the city centre with rooms starting from £66 per night.
The hotel was originally converted from a boys’ grammar school, and offers a range of artwork and unique architecture that serve as a reminder of its history.
My suite was spacious, with a sofa, Nespresso machine, deluxe king-size bed and bath – along with a view onto the courtyard.
There are many areas to relax, such as the breakfast room, afternoon tea area or the terrace, where you can spend an afternoon being served cocktails by expert mixologists.
How to get there
For those travelling from London, it’s worth considering taking a train.
The train from Kings Cross takes just two hours, with prices starting from £43.50.
Making the journey by car, however, allows those who are up for a little adventure to go for a drive around the Peak District and Sheffield’s surrounding areas.
Get need-to-know travel news, inspiration and advice from Metro every week.
Sign up here...
Not convinced? Find out more »


On Friday, the ACB Selection Committee announced the decision to remove Afghan from the national team’s captaincy across all three formats. In his place, Gulbadin Naib (ODI), Rashid (T20I) and Rahmat Shah (Test) were named as the skippers in a split captaincy.
Taking to Twitter to express his opposition to the move, Rashid wrote, “With all the respect to the Selection Committee, I strongly disagree with the decision as it is irresponsible & bias.”
“As we have the World Cup in front of us, Asghar Afghan should remain as our team Captain. His captaincy is highly instrumental for team success. With just months to go for such a mega event like World Cup, changing the captain will cause uncertainty and also team morale will be affected,” the leg-spin sensation added.
With all the respect to the Selection Committee, I strongly disagree with the decision as it is irresponsible & bias. As we have @cricketworldcup in front of us, Captain #MAsgharAfghan should remain as our team Captain. His captaincy is highly instrumental for team success .(1/2)— Rashid Khan (@rashidkhan_19) April 5, 2019
Rashid’s Afghanistan and Sunrisers Hyderabad (IPL) team-mate Mohammad Nabi too took to social media to voice his support for Asghar Afghan.
“Being a senior member of the side and having seen the rise of Afghanistan cricket, I don’t think it is the right time to change the captain before the World Cup. The team has gelled really well under Asghar and personally feel he is the right man to lead us,” the all-rounder wrote.
Being a senior member of the side & having seen the rise of Afghanistan cricket @ashrafghani I don’t think it’s the right time to change the captain before the WC @afgexecutive The team has gelled really well under #Asghar & personally feel he is the right man to lead us @hmohib— Mohammad Nabi (@MohammadNabi007) April 5, 2019
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The 23 players who have been included in the list will attend a two-day training camp at the National Cricket Academy (NCA) in Lahore beginning on April 15 where they will all be asked to prove their fitness.
Following the completion of the fitness camp, the final 15-man Pakistan squad for the World Cup will be announced on April 18.
The biggest omissions in the 23-man probable squad are Umar Akmal and Saad Ali who both recently featured in the ODI series against Australia in the UAE where Pakistan were handed a 5-0 drubbing.
While Akmal and Saad Ali have been left out, there is a place for specialist Test seamer Mohammad Abbas, leg-spinner Yasir Shah as well as Shan Masood who scored a half-century in the series against Australia.
There was good news for pacer Mohammad Hasnain as well with the youngster finding a spot in the 23-man squad. 18-year-old Hasnain had impressed for Pakistan Super League (PSL) champions Quetta Gladiators before he was handed his maiden international outing in the series against Australia.
The Men in Green will depart for England for the World Cup on April 23 where they will play a couple of warm-up games against Kent and Leicestershire. Pakistan will then take on hosts England in a five-match ODI series as well as a sole T20I before opening their World Cup campaign on May 31 against West Indies at Trent Bridge.
23-MAN PROBABLE PAKISTAN SQUAD
Sarfaraz Ahmed (c), Abid Ali, Asif Ali, Babar Azam, Faheem Ashraf, Fakhar Zaman, Haris Sohail, Hasan Ali, Imad Wasim, Imam-ul-Haq, Junaid Khan, Mohammad Abbas, Mohammad Amir, Mohammad Hafeez, Mohammad Hasnain, Mohammad Nawaz, Mohammad Rizwan, Shadab Khan, Shaheen Shah Afridi, Shan Masood, Shoaib Malik, Usman Shinwari, Yasir Shah.
Afghanistan skipper Asghar Afghan has been relieved of his duties with the country’s board appointing new captains for all three formats on Friday.
Asghar Afghan had been leading the national team across all three formats previously but the Afghan board have now decided to go the route of split-captaincy for the three formats. Asghar Afghan has been removed from the leadership role with Gulbadin Naib, Rashid Khan and Rahmat Shah announced as the new skippers for the three formats.
The decision to do so was taken on Friday following a meeting of the Afghanistan Cricket Board (ACB) Selection Committee.
It will be 28-year-old all-rounder Gulbadin Naib who will lead the team in the ODI format and thus the upcoming 2019 ICC World Cup in England. Leg-spin sensation Rashid Khan will serve as Naib’s deputy in the 50-over format while the 20-year-old will take over as skipper in the T20I format.
ACB Selection Committee announced changes in team Afghanistan's leadership across formats as follows.— Afghanistan Cricket Board (@ACBofficials) April 5, 2019
- @GbNaib Captain
- @rashidkhan_19 V. Captain
- @rashidkhan_19 Captain
- @shafaqshinwarai V. Captain
- @RahmatShah_08 Captain
- @Hashmat_50 V.Captain pic.twitter.com/zRRvwgtKFF
Rashid is the No1 ranked T20 bowler in the world and it is the first time that the wrist-spinner has been appointed to a leadership role in the Afghanistan setup. Meanwhile, Shafiqullah Shafaq has taken over as the new vice-captain in the T20I format.
25-year-old all-rounder Rahmat Shah has been announced as the new Test skipper of the side with Hashmatullah Shahidi announced as his deputy.
Afghanistan have played two Tests so far since they were given the Full ICC membership with Shah playing a part in both the matches. The right-handed batsman has scored 198 runs in those two Tests at an average of 48.


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domain: entertainment


Dell's PowerEdge R900 offers a powerful system for virtualising operating systems and consolidating physical servers, with the major virtualisation packages supported.
Easy set up and manageability using OpenManage Server Administrator; supports Citrix, Microsoft and VMware virtualisation environments; powerful performance for the price.
No virtualisable network interface card offered as option.
£ 6,573 starting price. As configured on Dell web site $32,567 (£21,500)
Although originally launched this February in the Philippines, Dell's R900 PowerEdge was upgraded with Intel Dunnington series six-core processors in October.
The PowerEdge R900 is a rack mount 4U system, which has four processor sockets and can have a maximum of 256GB of system memory. Our system had 16Gb of 667MHz memory installed, and three 2.5in form factor serial attached SCSI (SAS) 10,000 rpm, 146GB hard drives configured as a single virtual disk SCSI device.
There are drive bays for up to eight 2.5in drives, but users can specify a backplane for up to five 3.5in drives.
Our R900 had a full complement of four Intel 2.66GHz Xeon E7650 series six-core processors installed, running with a 1066MHz front side bus. These 45nm, 1.9 billion transistor, Penryn-based CPUs do not have HyperThreading technology, which a quick check in the Windows task manager performance tab shows - we could see 24 processors.
Firing up the system brings a sound like an aircraft taking off but, since the server will reside in a dedicated room or datacentre, ear defenders won't be needed.
Our review system had Windows Server 2008 Enterprise Edition installed, but all editions are supported, as are Red Hat Enterprise Linux 4.5, Sun Solaris 10, Suse Linux Enterprise Server 10 and Windows Server 2003 R2.
Virtualisation software offered with the R900 includes Hyper-V. Off-the-shelf systems come with either VMware's ESXi 3.5 or Citrix's XenServer 4.1 installed, and Dell's embedded hypervisor also supports Sun Solaris on the x86 platform. Virtualisation software supported on the R900 includes Citrix XenServer, VMware's Infrastructure 3.5 and VMware's ESXi 3.5.
It was simple to enable the Hyper V Microsoft Management Console snap-in, but the R900 had to be fully patched using Windows Update before this was possible. Using Microsoft's Hyper-V virtualisation system was simple and, although its management GUI seemed fairly intuitive, Microsoft's System Center Virtual Machine Manager 2008, which we installed later, appeared less so.
Space taken up by the 64-bit edition of Windows Server 2008 Enterprise Edition was 24.8GB out of a total capacity of 383GB. As a comparison the 32-bit edition of Windows Server 2008 occupies a similar amount of disk space at just under 24GB.
We attached the system to our itweeknet.com domain and imaged the system. After enabling the WS 2008 backup and restore feature, the compressed image used just under 9GB of disk space, and restoring the system to its original image was trivial.


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» Lue blogi... Julkaistu: · Päivitetty:
This year's Suvi-Vintage poster that I did got summery vibes from the late 1950's. The vintage fair is in Tampere 29-30.6. I am performing elsewhere but you go! And now I am off to Paris! Peforming on Wednesday, there until Friday evening. Last time I was there was twenty-one years ago, so hit me with your best and most charming to-do's there!

domain: hobby


SPECIES Tirachoidea westwoodi
FRAME 33.5x37.5xD5cm Made from recycled products.
DESCRIPTION Huge female stick insect . Phasmids ( stick insects ) are nocturnal there are around 150 species found in Australia.
The longest Australian phasmid is the Titan Stick Insect (Acrophylla titan) which can grow to 25 cm long, the rarest is The Lord Howe Island Phasmid or Land Lobster (Dryococelus australis) which may be the rarest insect in the world, and possibly also the rarest invertebrate.
Not available for international postage


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If you are a comic book fan then this is a must-watch. The state of comics today, both British and American, is so ingrained in the history of the comic book 2000AD that there is plenty fans of the genre will love here. This is the greatest strength of Future Shock, it is by the fans, for the fans.
This means you get a no-holds barred, unchecked look at the story of the comic book which this week celebrates it’s landmark 2000th issue. It isn’t a dull history either, coming close to closure on numerous occasions, as well as spawning and nurturing some of the greatest comic book writing talents in the industry today.
That is the other impressive aspect of Future Shock, it is so well-told by the witnesses of the time. From 2000AD creator Pat Mills, through to early talents like Dave Gibbons and Neil Gaiman and then on-wards to some of the comic book heavy-hitters like Grant Morrison. They all get a chance to tell their story and in an uncut, uncensored way, which is made even more interesting once an argument is brought to light and the two parties get a chance to give their conflicted views.
The trouble with doing a comic book documentary is that the vignettes between interviews are restricted to mainly stills but when the animation, art and sequences are so inventive as they always were in 2000AD, you can’t help but become mesmerised by what is on-screen. Some of the creatures, stories and visuals featured have complete stories to themselves, no more so than the comic’s greatest creation: Judge Dredd.
Future Shock is a fantastic documentary for the comic book fan. This is where the main issue lies though because if you’re not a comic book fan, you probably won’t care. The best documentaries can entertain anyone, regardless of prior interest but Future Shock doesn’t try that here. It is a film by the fans, for the fans and is unapologetic about it. Whether this is a negative is up to personal preference and opinion.
Overall, Futureshock! The Story of 2000AD does exactly what it says in the title but perfectly. It is an in-depth, uncensored and unabridged history of one of the most influential series in comic book history. An essential for comic book fans, but unfortunately, probably not everyone else.
Rating – 4
(1 – Awful, 2 – Average, 3 – Good, 4 – Great, 5! – Must See)


The city of Deltona enjoys a distinct type of weather every year. Having been located in Central Florida, this means that the city enjoys both the sub-tropical climate of Southern Florida and the more pleasant climate of the Southeastern states. While most of the cities in Florida experience a generally warm and humid weather all throughout the year, the city of Deltona gains from its strategic location by just having the right amount of sun and rain.
However, just as much as the benefit it gets from a fine weather (Orange Pest Control), is the fear from the pests that are eager to capitalize on every given opportunity. Pests such as ants, bugs and mosquitoes are always on the look out for a comfort zone, thus leaving your home vulnerable from their attacks (Daytona Beach Pest Control).
During the summer season, these pests would head straight to your house for them to absorb moisture. On the other hand, when the rain starts to fall, it will still be your home that will serve as their haven for them to stay dry. So what does this mean? This simply means that you should control (Daytona Pest Control) these pests all year round!
Why is a pest control service necessary? Employing one is essential (Deltona Pest Control) to keep your home protected from the pests that might reside in every corner of your house. In Central Florida cities like in Deltona, an efficient pest control service (Daytona Pest Control) assures that a home is well guarded from these pests no matter what the state of the weather is.
Cleaning your backyard or garden may be a good start, but it is not enough to keep your house pest-free (Daytona Beach Pest Control). Building and maintaining the proper drainage and sewerage system is the right approach (Palm Coast Pest Control) if you want the pests go away for a long period of time. Open sewers are breeding grounds of mosquitoes and flies; thus, these sewers must be maintained in order to eliminate the problem. Others even hire workers to have this job done (Daytona Beach Pest Control).
Using poison sprays is also a common type of pest control service. It is effective in killing airborne pests that transfer from one area to another. Towns oftentimes have trucks that visit every house in the neighborhood to spray out the pests. Poison sprays and chemical pesticides are relatively inexpensive and can be used every time when the need arises.
Meanwhile, if the pests prove to be a major problem already, then a Space Fumigation might be the pest control service (Palm Coast Pest Control) that can fully address the threat. The area to be treated must be fully enclosed, and only professional fumigators are allowed to stay. Since a deadly gas is used on this procedure, the proper suit and equipment must be worn for them not to inhale the poison. The concentration (Daytona Beach Pest Control) usually lasts for about a day or two to ensure that no pests are left out.
No matter how light or serious your pest problems are, always make sure that you always look after your surroundings (Palm Coast Pest Control). We just never know when these pests will attack the next time.
There are numerous pest control services being offered around Deltona. All you have to do to find one is to search the web.


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The Science Behind the Durability of Aircraft Steel
Aircraft Steel is great for the aerospace industry's important stressed parts and components.
Aircraft steel is highly durable due to its unique composition and manufacturing processes. It consists of high-strength alloys that are designed to withstand the harsh conditions of flight, including extreme temperatures, high stress loads, and exposure to corrosive elements.
Resistance to fatigue is a key factor in aircraft alloy steel’s durability. Fatigue weakens a material over time due to repeated stress cycles, which can cause aircraft components to fail. To prevent fatigue, specialized coatings or surface treatments are often applied to the steel to enhance its corrosion and wear resistance.
Maintaining its strength and stiffness at high temperatures is also crucial for aircraft alloy steel’s durability. Turbine blades, for example, must withstand temperatures over 1000°C. Alloying the steel with elements like chromium, molybdenum, and tungsten improves its high-temperature performance, ensuring its strength and durability in even the most extreme conditions.
How Aircraft Steel Contributes to Safe and Efficient Air Travel
Aircraft steel plays a crucial role in ensuring safe and efficient air travel. Its strength and durability enable it to withstand high-stress loads and harsh flight conditions, providing passengers and crew with a high level of safety and reliability.
This steel is used in various applications, from the airframe’s structural components to the engine and landing gear. These parts must resist corrosion and wear while withstanding extreme forces and temperatures.
Besides its strength and durability, aircraft alloy steel offers other benefits contributing to safe and efficient air travel. Its high stiffness-to-weight ratio allows for lightweight yet robust components, reducing the aircraft’s weight and enhancing its fuel efficiency. This, in turn, can lower operating costs and decrease the environmental impact of air travel.
In summary, the use of aircraft alloy steel is crucial for maintaining modern aircraft’s safety, reliability, and efficiency. Continual improvements and optimizations of this material by engineers can help ensure air travel remains one of the safest and most efficient modes of transportation.
Get the Best Quality Aircraft Alloy Steel Supplies
At Advance Grinding Services, we specialize in providing high-quality aircraft alloy steel supplies. These meet the aviation industry’s rigorous standards. We commit to delivering top-notch products and services to our customers and work closely with them to understand their specific requirements.
Our aircraft steel supplies are designed to withstand harsh flight conditions, including high stress loads, extreme temperatures, and corrosive elements. We offer value-added services such as precision grinding, custom cutting, and heat treating to provide our customers with high-quality products that meet their precise specifications.
Whether you manufacture aircraft components, provide aviation maintenance services, or supply to the aviation industry, our company has the expertise and experience to provide you with the best quality aircraft alloy steel supplies. We are committed to delivering unmatched quality, service, and customer satisfaction, and we aim to help our customers succeed in their businesses.

domain: chemistry


A laptop and a connection to the Internet are my lifelines!
I spent about an hour uploading one 4mb powerpoint doc. That doc probably cost me $100 to upload.
Traveller Racks Up $1,520 Internet Bill on Singapore Airlines
Unlimited data can be obtained at a flat fee of US$7.99 per day.
Unlimited mobile data in 55 countries!
First Minute of your Call Free Until End of 2014 – Google Hangouts
Why You Need 2-Step Authentication While Travelling
Need to work on Google Docs but can’t find the Internet?
Best Power Bar for Travel (110v, 220v)
Mac WiFi County Code Fail (Channel 13)
Help, I lost my travel photos!


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Here you have the opportunity to have your logo printed exclusively on the tactical sweatshirt.
In addition, we will print your desired name on the collar for free. The sweatshirt is then, without exception, one of a kind, of which there is no other.
Please deliver motifs in an appropriate quality and with a maximum diameter of 90 mm.
Please pay attention to the applicable law for motifs, forbidden motifs will not be printed and will be deleted without exception!
The sporty sweatshirt (sweater) with a high-closing collar has a short zipper on the front, which provides additional ventilation. The inside made of fluffy fabric keeps you warm and the elastic cuffs and hem prevent cold air from entering.
- 2 large upper arm pockets with zip
- Upper arm pockets with headphone output
- Velcro area on upper arms for attaching patches
- sporty sweater with high-closing collar
- short zipper
- fluffy, warm inside
- elastic cuffs on sleeves and hem
- Material: 60% cotton, 40% polyester


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Archive for 'Zika Virus Q & A'
Zika Virus Q & A
Q: How is Zika virus transmitted? A: Zika virus is spread through the bite of an infected Aedes genus of mosquitoes, which is the same type of mosquito that carries dengue fever and chikungunya. Aedes aegypti mosquitoes, which live predominantly in tropical and sub-tropical regions, are the primary carriers, but Aedes albopictus mosquitoes might also…Read More


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Beyonce's 'Lemonade' tops the Billboard 200 album charts this week, moving 635,000 units, sales plus streaming.
On the one hand, that is an extremely strong number and the biggest opening of the year so far. On the other, it is just a fraction of what Adele (3.48 million first week for 25) and Taylor Swift (1.28 million for 1989) were able to bring in first week with their last albums.
And now with Drake projected to do between 1.2 million and 2 million first week for Views, it's clear that despite all of her star power, Queen Bey isn't quite a top tier artist when it comes to album sales.
Neither is ASAP Ferg, by a long shot. His sophomore album Always Strive and Prosper opens at No. 8 with 35,000 units, sales plus streaming. That's 3000 more than his debut album Trap Lord did first week in 2013. But it's also about 3000 less than Young Thug's Slime Season 3, a mixtape, did last month.
Last May, Ferg's A$AP bro Rocky's album, At. Long. Last. ASAP, did 116K during its first week.
Did you hear any good albums this week?

domain: celebrity


Low-arsenic water can be used for ingesting, cooking and irrigation purposes, whereas high-arsenic water can be utilized for different functions similar to bathing and washing clothes. Prevention of further exposure to arsenic can be achieved by the supply for provide of arsenic free / sfae water for consuming, food preparation and irrigation of food crops. It is very poisonous in its inorganic kind.Arsenic and its compounds, particularly the trioxide, are used in the production of pesticides, treated wooden merchandise, herbicides, and pesticides.
Previous research (O’Neill 1995) indicate that uptake of CCA into the grapes is unlikely. Lesser sources of arsenic contamination in New Zealand originate from coal ash disposal, and the mining industry (Nriagu and Pacyna 1988; Eisler 2004). Arsenic trioxide is extensively used within the manufacturing of ceramic and glass, electronics, pigments and antifouling brokers, cosmetics, fireworks and Cu-based alloys . Coal combustion not only releases gaseous arsenic into the ambiance but additionally generates fly and backside ash containing various amounts of arsenic. Disposal of those materials typically leads to arsenic- contamination of soil and water .
Pesticides containing arsenic have been utilized to golf course turf grasses throughout Florida for many years . Chen et al. reported that a survey performed on one hundred fifty five golf programs confirmed that 96% turf grasses were sprayed with MSMA from 2 to three times per yr with a loading fee of about 224 kg/km2. A collaborative investigation carried out by the Dade County Department of Environmental Resource Management and the Florida Department of Agriculture and Consumer Services assessed arsenic contamination at five golf courses .
Dumat, 2014a, Foliar uptake and metallic bioaccessibility in greens exposed to particulate matter. Effect of prestain on the release price of copper, chromium and arsenic from Western Hemlock. 2Institute of Natural Resources, Massey University, Palmerston North, New Zealand. Benavides AM. The impact of arsenic speciation on arsenic uptake and destiny in the presence of the hyper-accumulating species pteris cretica. As local weather change handshakes water contamination, we cross by very a lot uncertain instances.
Since arsenic is rapidly metabolized and excreted via the urine, this measurement can provide proof of current arsenic exposures . Moreover, the introduction of POPs to the surroundings from organic wood preservatives corresponding to PCP, polychloronaphthalenes, dieldrin, DDT, lindane, and chlordanes has precipitated a worldwide public well being concern. The continued economic development actions corresponding to wooden remedy and the commercial revolution will irritate the availability of secure ingesting water and injury soil quality. As a end result, research should explore adaptive applied sciences and methods in line with heavy metallic and natural air pollution remediation of wooden therapy websites. Fe nano-particles have been successfully applied in adsorbing and degrading heavy metals and natural contaminants, notably organic chlorinated solvents and polychlorinated biphenyls in groundwater and soils.
A research reveals that prime arsenic contamination of groundwater in Bihar is linked with enhance in most cancers circumstances. Cytotoxicity develops when cell represents anomalies attributable to poisonous chemicals/contaminants. Arsenic led cytotoxicity in cells by way of several pathways has been explored by a number of researchers . ROS ranges contained in the cell increase dramatically when cell is exposed to elevated stage of As.
Adsorption of arsenic is a fancy operate of the interrelationship between the properties of the solid floor, pH, the concentration of arsenic and competing ions, and arsenic speciation . Oxides of iron, aluminum, and manganese are often the most important sources or sinks of arsenic because of their chemistry, widespread prevalence, and tendency to coat different particles . Arsenate adsorption is far stronger at lower pH values, with considerably less adsorption occurring above pH 7. Arsenite adsorption, quite the opposite, increases with rising pH, reaching a maximum at between pH eight and 9 .
Morales KH, Ryan L, Kuo TL, Wu MM, Chen CJ. Risk of inner cancers from arsenic in ingesting water. Buchet JP, Lauwerys R, Roels H. Urinary excretion of inorganic arsenic and its metabolites after repeated ingestion of sodium metaarsenite by volunteers. Hindmarsh JT, McCurdy RF. Clinical and environmental aspects rmc water and environment research of arsenic toxicity.
Presence of interfering substances corresponding to Fe, Mn, sulfide (HS− and S2−), whole natural carbon , and dissolved organic carbon have an effect on the oxidation of in water samples. In the presence of S2- and TOC, the oxidation rate of by ozone severely declines . The arsenic concentrated in the pyrite grains within these predominantly carbonate rocks tends to remain motionless unless the system is exposed to oxygen and/or different oxidizing brokers (e.g., nitrate). Injection of oxic water during aquifer storage and restoration operations demonstrates the release of the arsenic from the pyrite .
At least one of these species, watercress (Rorippa nasturtium-aquaticum), is consumed by people. Other aquatic crops may be periodically consumed by stock which have access to waterways. Ground and floor water used for irrigation could lead to accumulation of arsenic in agricultural soils. Chromated copper arsenate is a pesticide and wooden preservative which is a potential supply of arsenic exposure and toxicity .


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It’s so difficult to describe depression to someone who’s never been there, because it’s not sadness. I know sadness. Sadness is to cry and to feel. But it’s that cold absence of feeling— that really hollowed-out feeling.
Before you say yes, get him angry. See him scared, see him wanting, see him sick. Stress changes a person. Find out if he drinks and if he does, get him drunk - you’ll learn more about his sober thoughts. Discover his addictions. See if he puts you in front of them. You can’t change people, baby girl. If they are made one way, it doesn’t just wear off. If you hate how he acts when he’s out of it now, you’re going to hate it much worse eight years down the road. You might love him to bits but it doesn’t change that some people just don’t fit.
inkskinned, “My father’s recipe for the man I should marry” (via partygirlmeltdown)
This is one of the most important things I have ever read and I wish I would have come across it sooner. This is real, this is important.
I think this changed everything I thought about loving a boy
He looked at me like I was crazy. Most of my lovers do, and that’s partly why they love me, and partly why they leave.


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She gasped to speak, forcing syllables out in rapid succession.
My heart ached to witness her pain.
Silently, I spoke from my heart to hers, holding her in a completely safe space.
You are safe. You are loved. You are free. You have all the support you need.
She made it here, despite debilitating anxiety, because she realized this was the anniversary of her rape.
Her conscious mind didn’t know, couldn’t remember, but her body was speaking with tremendous clarity.
The feelings had begun to ramp up again about three months ago. We realized this was the season she had first connected with the family friend who would traumatize her.
Through her courageous sessions, we had successfully eased her mind and heart and increased her self-confidence. She had made tremendous progress, but had now entered the epicenter of remembrance of the most traumatic event of her life. And she discovered that, right here, in the middle of the pain, there is tremendous power.
Once she had forced the words out and let the tears flow, she began breathing easier. This is when we created a plan to make this better for the rest of her life.
Now it’s your turn.
Here are the exact keys to easing stress on the anniversary of trauma, whatever that trauma might have been:
1) Honor your body’s message.
Even if it feels like you might drown, it is essential to let your innermost self know that you get it, that you are paying attention, and that you will find help. I promise that when you consistently listen and respond reassuringly, you will lesson the “2 x 4 effect.”
2) Assume a position of power.
This is where you take a stand to make this better. When you establish a fierce commitment to help the delicate parts of yourself navigate this time with greater support, you will find yourself relaxing and feeling healthier energy flow to you.
3) Ask for support from safe people.
This is not a time to go it alone. Contrary to popular belief, asking for help shows wisdom, strength and adaptability that can bring great resilience.
4) Write the date on your calendar as a time to nourish yourself.
I recommend noting the 10 day window around the anniversary to encourage advance preparation in future years. By committing to giving yourself extra self love during this time for the rest of your life, you will harness tremendous supportive resources.
5) Give yourself what you need in the moment AND pre-plan sweetness for the future.
Create a list of all the things that will feel nurturing to your spirit. Write down all the things you love to see, feel, taste, touch and hear, along with safe people you can reach out to in advance to support you with great love. Start a self-care box with sweet nothings to collect in preparation for the next anniversary.
6) Follow through.
Know that by doing so, you are proving to yourself that you are a trustworthy custodian of your own heart. In short order, you will find your trust in yourself grows and you will navigate future anniversaries with greater ease.
Do you have a special tip that has helped you ease stress on the anniversary of trauma? I would love to hear about it and help spread healing in the world!

domain: psychology


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Kirk Jockell is an Indie Writer, Photographer of Sailboats, and Avid Sailor.
He’s a writer and the author of the three book series Tales from Stool 17; The Nigel Logan Stories. Each book is made up of stories. He actually thinks of them as episodes. The final book in the Stool 17 three part series was released May 2017. If you asked him if it’s best to read them in order, he would say, “Yeah! I have a yacht payment due. But more importantly, each of the following volumes are built upon the others.
- Volume one of the series is subtitled Finding Port St. Joe.
- Volume two of the series is subtitled Trouble in Tate’s Hell.
- Volume three of the series is subtitled: Dark Days of Judgment
While the Stool 17 trilogy is done, Jockell is not. He still has other projects bouncing around in his brain that make him very excited.
As for sailing, he races, cruises, and day sails for simple pleasure. His real interest in sailing is single-handed sailing. While he enjoys the camaraderie and crew work of sailing with others, he especially loves the idea of One Man … One Boat. He says, “When it’s just you and the boat, it just doesn’t get any better than that.” And when not actually sailing, he can often be found tinkering on whatever flavor of boat he currently has in a slip.
His love of sailing gave birth to a passion for photography. He loves shooting sailboats, so it is shouldn’t be a surprise when his main character, Nigel Logan, supplements his Navy retirement check by travelling around shooting regattas. Even though he is reluctant to admit it, he probably enjoys framing a boat through his lens more than sailing itself. He struggles with both. And he never complains about the hours it takes to mull over hundreds of shots taken at regattas.
He hails from the small, coastal town of Port St. Joe, Florida, but platoons his time up around Georgia’s Lake Lanier where he commutes to Atlanta for what remains of his work with a regular job–not sexy enough to mention here.
He is married to his lovely wife of 30+ years, Joy. They live with their black cat, Stormy (that still pukes a lot), and a bottle of Jim Beam.


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Fall down the rabbit hole again and again with Adam Sabuda's best creation yet! Building on his reputation as one of the most innovative paper-engineers working in children's books, Robert Sabuda dazzles us with his reworking of Alice in Wonderland. The book consists of 7 spreads with breathtaking super-size pop-ups and additional pop-ups contained within mini story books. Special effects include printed foil, acetate pull-tab scenes and on the first spread a peep show of Alice falling into Wonderland. Praise for Alice's Adventures in Wonderland: A Pop-up Adaptation:'breathtaking, three-dimensional images that are incredibly imaginative, intricately detailed, and perfectly executed... a fresh look at the story and offering details that add greatly to the reading experience.' School Library Journal'This will very likely come to be seen as the definitive pop-up version of Alice, but it will also further establish Sabuda as the foremost visionary of the genre.' Booklist, Starred Review
Beautifully made from fine bone china these Victoria & Albert set of side plates are illustrated with scenes from the original Alice in Wonderland book.With a variety of scenes with Alice and the White Rabbit in a whirlwind of playing cards with the words 'oh dear! oh dear! I shall be too late! and 'have I gone mad?' hand drawn illustrations with luxury gold decal.These stunning side plates are presented in gorgeous illustrated packaging with a puzzle enclosed to begin your adventure.
Collecting Alice's complete adventures, a source of delight to children and adults alike for generations, the Penguin Classics edition of Lewis Carroll's Alice's Adventures in Wonderland and Through the Looking-Glass is edited with an introduction and notes by Hugh Haughton. Conjured up one 'golden afternoon' in 1862 to entertain Alice Liddell, the daughter of the dean of Carroll's college, the dream worlds of nonsensical Wonderland and back-to-front Looking-Glass kingdom depict order turned upside-down. Following the white rabbit into his warren, Alice falls into a world where croquet is played with hedgehogs and flamingos, a baby turns into a pig, time runs amok at a the Mad Hatter's tea-party, a chaotic game of chess makes Alice a Queen and the Mock Turtle and Gryphon dance the Lobster Quadrille. But amongst the anarchic humour and sparkling wordplay, unforgettable characters, puzzles and riddles, are poignant moments of nostalgia for a lost childhood. Original and experimental, adapted into countless film and television versions as Alice in Wonderland, the Alice books give readers a window on both child and adult worlds. This is the most comprehensively annotated edition available and includes the manuscript version of Alice's Adventures Under Ground and Carroll's 1887 essay '"Alice" on the stage'. Lewis Carroll (1832-1898) was the pen-name of the Reverend Charles Lutwidge Dodgson. Educated at Rugby School and Christ Church, Oxford, Carroll was appointed lecturer in mathematics in 1855, where he spent the rest of his life. In 1861 he took deacon's orders, but shyness and a constitutional stammer prevented him from seeking the priesthood. If you enjoyed Alice's Adventures in Wonderland you might like Mikhail Bulgakov's The Master and Margarita, also available in Penguin Classics. 'A work of glorious intelligence and literary devices ... nonsense becomes a form of higher sense'Malcolm Bradbury
Showcase your love for Alice In Wonderland with this superb Alice In Wonderland Clutch Purse! This unique Alice In Wonderland Through the Looking Glass Purse is made from premium materials and is built to last and make you stand out from the crowd!It has 12 Card Slots (Includes Coin & Large Slip Pockets) and also a 85mm note area for UK 20 & Euro 100 notes to fitReplace your old Purse now or buy the perfect gift for any Alice In Wonderland fan!The design of the Purse is Clutch and it includes an area for notes, credit cards slots and space for your Coins. The Purse is approximately 100mm x 200mm x 25mm. The interior is fully lined and detailed pattern accentuates the features
DIFFERENT OFFER (this item listed here is DIFFERENT from the title and/or picture above. Please see description & pictures by BookGems before placing an order): Edition Macmillan Children's Books, A Special Centenary Edition, First Impression 1998. Includes two titles in ONE volume: Alice's Adventures In Wonderland (192 pages) & Through The Looking Glass (240 pages). With illustrations by Sir John Tenniel coloured by Hary Theaker and Diz Wallis. ISBN: 0-333-72272-8. HARDBACK. 436 pages, large size: 19 x 3.5 x 25 cm. The book remains in very good condition: dust cover intact albeit light rubbing to edge; dark navy cloth bound cover bright with gilt lettering on spine; text all clean, neat and tight. Immaculate throughout. Prompt dispatch from UK.
This set of 4 Alice in Wonderland teaspoons are made with high quality stainless steel and porcelain handles.The handles are decorated in beautifully hand drawn illustrations, featuring the Alice and the White Rabbit and features the quote 'Curiouser and curiouser'. The set of four teaspoons are presented in a luxuriously illustrated matching gift box, with a 'pull me' tab to let the adventure begin. Each teaspoon length: 15.5cm.
Full set of playing cards themed and designed for the classical novel Alice in the wonderland. Perfect for Alice in the Wonderland themed events or garden parties. These can be used as decorations or as normal playing cards, with a vintage look, yet laminated back and front. These come in a box including jokers, and sealed. Each face cards is printed with original Alice in the Wonderland art work.
Britain's most beloved character has come to life in this stunning printed scarf! This scarf features a repeated print of hand drawn illustrations commissioned by Molly Louise that were inspired by the original Charles Lutwidge Dodgson (better known under his pen name pseudonym Lewis Carroll) illustrations featured in his 'Alice's Adventures in Wonderland'. A plain white background provides the perfect background for the ink style drawings of Alice, and other key pieces and characters. A smiling Alice wearing her Disney outfit of pinafore and large bow hair band is surrounded by the Mad Hatters top hat, the White Rabbit's stopwatch, a 'Drink Me' potion and of course, the Queen of hearts delicately plotting from within a playing card frame. The quote 'Curiouser and curiouser' finished the theme. Made from a lightweight Viscose, this scarf will keep you warm without the bulk, and the large size provides a choice of styling options
A gorgeous selection of Alice's Adventure in Wonderland tins, with illustrations from the incredible Sir John Tenniel, containing three tins of the finest loose leaf teas. These tins include 'English Breakfast Tea', a traditional full flavour blend, 'English Afternoon Tea', a refreshing blend of fine teas and 'Earl Grey Tea', a traditional blend with the added flavour of Bergamot. Carefully selected to ensure the finest aromas, this collection of Ceylon fine blends is sure to be enjoyed and will make the perfect gift for any occasion. Net weight: 70g Best before date: August 2019 Each tin measures: 6.5 x 4.5 x 4cm.
Beautifully made from fine bone china this Victoria & Albert high tea gift set is illustrated with scenes from the original Alice in Wonderland book.Portraying the well-known Mad Hatter's Tea Party in hand drawn illustrations with luxury gold decal including the words 'we're all mad here'.This stunning mini teapot is presented in gorgeous illustrated packaging with a puzzle enclosed to begin your adventure.