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With Oliver in prison and Ricardo Diaz still on the loose when Arrow returns for its seventh season next month, Team Arrow is going to have to find a way continue to protect Star City without Green Arrow and it sounds like that challenge will be a driving force for the team.
Speaking with ComicBook.com at San Diego Comic-Con back in July Dinah Drake/Black Canary actor Juliana Harkavy explained that the heroes would have to get "crafty" with Oliver behind bars.
"Well, everything is a little bit under constraints because of what's going on with Oliver so it's definitely going to be there, but they're going to have to be a little bit crafty in how they go about it," Harkavy said before explaining that defining themselves as heroes without Oliver would be a significant part of the season.
"I think everybody kind of has to step up in their own way. In a large part I think that's what this season is really going to be about like how do we see ourselves as heroes without our leader," she said. "It's going to come in a lot of different forms for Dinah."
Of course, there will be challenges to seeing the team step up. As fans of the show will recall, Team Arrow completely broke apart last season. First, Renee/Wild Dog (Rick Gonzales), Dinah Drake/Black Canary (Juliana Harkavy), and Curtis/Mister Terrific (Echo Kellum) broke off as their own team after what they felt was hypocrisy on Oliver/Green Arrow's (Stephen Amell) part. Then, Diggle (David Ramsey) and Oliver had a similar falling out. While they all came back together to face down Ricardo Diaz (Kirk Acevedo) and Oliver appeared to make amends before going off to prison, things aren't totally resolved.
The idea of the team continuing to be broken is something that Harkavy herself talked about in an interview with Entertainment Weekly at SDCC as well.
"I think the team is definitely broken, after all of the animosity that happened between us last season." Juliana Harkavy, who plays Dinah Drake/Black Canary, added. "And now the predicament Oliver is in, and just the sacrifice that he made for us. The hierarchy is broken, so we need to restructure and reevaluate how we approach the team."
They likely won't have any time to waste, either. Not only have photos from the season premiere revealed that at least one member of Team Arrow -- Felicity (Emily Bett Rickards) -- may be in direct danger, but Diaz is set to be even more dangerous than ever before with the addition of his Longbow Hunters in season seven.1comments
What do you think? Let us know your thoughts about Arrow's upcoming seventh season in the comments below.
The season seven premiere of Arrow, "Inmate 4587", will debut on Monday, October 15th, at 8/7c on The CW.


We are in the third year of a public health crisis that requires people to be able to shelter in place and yet, many lack access to safe, supported, adequate, affordable housing, and that access has only gotten worse during the pandemic. Now that our government has lifted the state of emergency, and the ban on renovictions, we could see more people on the streets. Schools are relied on to provide warmth and food to children due to government failure to provide adequate supports for families to afford this themselves. Nova Scotia has the highest poverty rates for children in the region, with 41,230 children or 24.3% living in poverty. Successive governments have failed to address food insecurity while we have the highest provincial rate of food insecurity. What about health care itself? Public health was never much of a priority, primary care practitioners, including family doctors, were already in short supply, and the pandemic has caused long waitlists for many procedures.
Despite these failings, the December fiscal update shows a provincial surplus, in part because of overestimation of impact the pandemic would have on revenue, and because of federal spending. We have the fiscal capacity to invest and we must. We cannot afford to waste this capacity on tax cuts or schemes that fail to address our deep social needs.
As Lars Osberg pointed out about the new government’s corporate tax cut, it could cost up to $200 million in revenue. But what will it accomplish when most of these companies would have increased their wage bills compared to last year anyway (including because of increases to minimum wage)? This is a subsidy Nova Scotians cannot afford. Moreover, the government should instead consider making our tax system more progressive by, for example, fully taxing capital gains or shifting federal tax deductions to refundable tax credits at the provincial level as we have outlined previously.
What should be reflected in the priorities of the new Nova Scotia government’s budget?
Our systems are not able to withstand small shocks, let alone big ones. This is concerning given the ongoing pandemic and likely future ones, combined with slow action on the climate crisis.
Many people continue to be left behind because of holes in our safety net. Many are now faced with further erosion in their standard of living as substantial price increases for essential needs, including food, eat away at their income.
We require significant investments to fill the gaps in our safety net, lift Nova Scotians out of poverty, address the housing crisis, and meet our health and social care needs. The care economy must be a focus for the investments, ensuring Nova Scotians can access the continuing care (long-term care, home care), child care, education, health care and social services that they need, while ensuring those providing the services receive decent wages and working conditions, including paid sick leave.
As we previously argued, “That the vast majority of COVID-19 deaths occurred in long-term care homes tells us that we must do a complete rethink on how we care for older Nova Scotians.” We absolutely must increase the quality of those homes, but we need to do much more. As the province with one of the largest shares of seniors, what if we develop solutions to make Nova Scotia more age-friendly? An age-friendly community would benefit everyone: barrier-free buildings and streets, affordable housing, well-paid caregivers and support, accessible and flexible employment opportunities, and expanded public health care, are some of the improvements that would be needed.
The cost of underinvestment
Compared to other provinces, we aren’t a big spender; our program spending of $11,987 per person (as of November 2021) is among the lowest of all provinces.
This is despite Nova Scotia’s demographics: an elderly and relatively large rural population makes it more costly to provide adequate health and education services, justifying higher-than-average spending. There is no justification for any retraction in spending—we know most spending on COVID came from the federal government (92% in NS), and now we have to deal with the pandemic’s aftermath.
For the current fiscal year, program expenses are projected to be 24.8% of GDP (which does not include debt servicing), and projected to continue going down. In 1981-82, program expenses were 26.8%. Needs have become more complex since 1981, not less. So why did government expenditure shrink? With Nova Scotia’s GDP well above $45 billion, the 2% decline in spending represents over $900 million dollars.
Even if additional spending means running a debt, we should be more concerned about this lack of investment, with debt-to-GDP ratio of 37.4% in March 2021 and projected to decline. Debt servicing costs as a percentage of expenditures have fallen to a decades low of 5%, and the government continues to be able to borrow at near-historically low interest rates, locking these in for decades.
The fiscal capacity is there to make the needed investments.
Inaction and underinvestment have a tremendous cost. Poverty costs Nova Scotians $2 billion dollars a year, which represents 4.8% of GDP. These costs include healthcare and criminal system costs, loss of productivity and the cost of children being trapped in a poverty cycle.
We have some of the lowest government income support programs in the country. Households who rely on the government as a last resort are in deep poverty. The Employment Support and Income Assistance rate for single parents with one child families is the lowest in the country, and even adding in federal support only provides that family with 57% of the Market Basket Measure poverty line. The system’s fundamental design remains—to keep families and individuals in deep poverty.
The pandemic showed that our health care system functions with very lean capacity in terms of its human resources and ICU capacity. Nova Scotia has one of the highest provincial rates of unmet health care needs. Investments in health care now needs to make up for decades of underinvestment. The solution is not to contract-out health care to deal with longstanding issues including wait times for surgery; we know that for-profit privatization only makes things worse. Instead, as the NS Health Coalition argues, we need “further investment in the public system and the introduction of organizational measures to maximize and increase surgical capacity including expanding the use of centralized referrals, creating a workforce development plan, and expanding community-based rehab and prehab clinics.”
Now is the time to also be investing in postsecondary education both to expand the spots available and to make education more affordable. There are two-year wait lists for many NSCC programs, including the licensed practical nurse program. Nova Scotia’s universities have the highest tuition fees in the country, averaging $9,028 (2021-22). Thus, our students also have the highest average debt at graduation. We know government funding as a percentage of operating revenues for universities has continued to drop; for example, Dalhousie University gets 44% of its revenue from government grants, while 46% comes from students, with particularly high fees for international students.
How can health care and other skilled labour shortages be addressed, when students face the highest tuition and graduate with the highest debt in the country?
Investments are needed
The pandemic has shown just how interdependent and connected we are, and just how important it is for us to build our collective strength.
We need a government willing to commit to fiscal fairness—where those who have more do their part, and our governments collect sufficient revenue to make the social investment required, which COVID-19 has shown is needed urgently. The pandemic is not over.
Nova Scotians deserve a government that learns the lessons of the past to build a better tomorrow.
Here are the top priorities that we want to see in the upcoming budget:
Invest in a Just Transition and Environmental Protection: Invest in a just transition for our economy that centres climate justice; e.g. cancelling the energy rebate that encourages consumption and redirecting savings (of about $100 million per year) to address energy poverty; ensuring investments in energy efficiency remove barriers for those least able to afford retrofits; and any investments in (re)training and skills-building must include targets to ensure equitable benefits for those who have been marginalized because of discrimination (underemployed, unemployed or low-paid). Further, as the Ecology Action Centre has advocated, the government needs to: properly resource the goals outlined in the Environmental Goals and Climate Change Reduction Act, as well as the forthcoming climate change plan, this includes improving public transportation infrastructure across the province.
Protect and Extend Public Health Care: Protect public health care by investing in front-line services, contracting-in to save money, and extend universal public health care by investing in: community health centres, long-term care, home care, mental health care, pharmacare, dental care, and vision care. Ensure that all residents no matter their immigration status have access to a NS health card, including international students, migrant workers and refugee applicants.
Tackle the Housing Crisis: Implement the 95 recommendations in the Housing for All report to ensure that all Nova Scotians have meaningful access to safe, permanently affordable, secure, supported, energy efficient housing, including in this budget cycle, making a targeted and large-scale investment in affordable housing units delivered via the not-for-profit, cooperative and public sectors (planning for 33,000 units in total), while also investing in core funding support for the community-based housing sector.
- Eradicate Poverty: Fully fund a comprehensive, robust Poverty Eradication Plan, developed using the Social Policy Framework, that includes targets and timelines that are embedded in legislation (as outlined in our child and family poverty report card).
Immediately invest to enhance income supports and address deep poverty, while working to ensure that the combination of current federal and provincial tax credits and income supports including the Nova Scotia Child Benefit, and the Nova Scotia Affordable Living Tax Credit, the Poverty Reduction Credit, equals 100% of the Market Basket Measure poverty line. All these benefits must include regular cost of living increases taking into account housing/rental inflation and food inflation.
Invest in proactive strategies developed with communities that have particularly high poverty rates to ensure policies and programs meet their needs.
Immediately end the practice of removing the Canada Child Benefit, Child Disability Benefit, and the Nova Scotia Child Benefit, from families when a child is brought into temporary care and custody.
Funding to ensure access to affordable essential infrastructure, including communications (cell phone, internet) and public transportation.
- Protect Human Rights and Provide Reparations:
Create a Child and Youth Advocate office to protect and promote the rights of Nova Scotia’s children and youth.
As outlined in the open letter by the Disability Rights Coalition, the government must “implement the Court of Appeal October 6 ruling, drop the application to the Supreme Court of Canada, negotiate a systemic human rights remedy to the problem of discrimination against people with disabilities in accessing social assistance, and end the funding cap which singles out the disabled and creates barriers to their inclusion in our communities.” Deinstitutionalization of persons with disabilities ensuring access to community housing and supports must be a priority.
Undertake substantive reform of the Nova Scotia Human Rights Commission, including, as recommended by Equity Watch, setting up a Human Rights Tribunal to deal with complaints and adjudication, and a Human Rights Legal Support Centre for complainants.
Continue to support First Nations in Nova Scotia to assume self-governance over child and family services and ensure all public services meet their cultural, historical, and geographical needs and circumstances.
Commit to reconciliation and supporting Indigenous self-determination, while decolonizing mainstream institutions, and implementing policies for reparations for African Nova Scotians as well, while ensuring all services in Nova Scotia are culturally safe for all.
- Invest in Education (from early learning to post-secondary):
Continue to increase funding to build a high quality, early learning and child care system that is child-centred, play-based, seamless (all day, full year), truly affordable, accessible, inclusive not-for-profit and publicly managed, so that every child under the age of 12 can have access. Immediately address low wages of ECEs.
Strengthen inclusive, high quality and safe, public education.
Increase funding to post-secondary education institutions, immediately lower tuition and commit to the eventual elimination of tuition fees (first at the NS Community College), while converting all student loans to grants, and provide student debt forgiveness.
Authors: Christine Saulnier, Director, CCPA-NS; with Mahmoud Elwaraki (Masters Student, Dalhousie Economics)


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Had a lovely meal here last week with friends. The staff are lovely and the food was so fresh and tasty. Will be back for sure.
1 - 10 of 406 reviews
I was here for lunch with some family. This pub has lots of old rugby memorabilia, so if you're a rugger fan you'll definitely appreciate it. We didn't want a big meal so we ordered some vegetable soup, seafood chowder, garlic mushrooms and then my...More
So went yesterday to grogans , very impressed , friendly service , served quite prompt. One downfull table for two can.be a tad crammed but thats minor. The food was so well.presented , the fish was cooked perfectly. Perfect portions . I.burnt my.hand but that...More
We ate here recently, excellent food, great staff. Portion sizes were huge - I could barely finish my main, still managed to squeeze in a dessert though. One small point to note, tables were very tightly packed together and we were literally elbow to elbow...More
Located in the centre of Glasson village this pub/restaurant is a must if you are in the area. Lovely food and a great friendly service
This is an absolute gem of a pub,its a must if in the area. We are on a weekend away and this place made our trip. Staff are top class so friendly and welcoming. Food was absolutely delicious excellent standard good portions quick service and...More
This olde world pub is a real hidden treasure. It looks tiny from the outside but there is a spacious restaurant at the back that offers absolutely fabulous food at very reasonable prices. The staff was great and all of the food was prepared perfectly...More
Brought some colleague from our US branch to Grogan's which was also my first time visiting. A very quaint old Irish pub full of character and charm. Decor was a little tatty but somehow that just added to uniqueness of the place. Food was excellent...More
As I'm from the states, I truly enjoyed the authentic charm of this Pub. Ireland is full of Pubs, so I don't know how one can go wrong, but I certainly wasn't disappointed.

domain: food


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Feb 21, 2019.
Scarless Revision Surgery after Gastric Bypass.
The revision is done entirely through the mouth and there is no scarring risk.
GASTRIC SLEEVE SURGERY ○ VSG ○ SURGERY ANNIVERSARY – Duration: 9:08. My Level.
There are also many patients whose insurance does not pay for weight loss procedures, especially revision procedures. Don't let the cost keep you from taking.
about StomaphyX and Transoral Rose, the newest bariatric surgery revision.
The weight loss surgery cost of StomaphyX and transoral ROSE is roughly.
Gastric Sleeve 10 Years Later Oct 19, 2018 · As a result, patients lose up to 70% of their excess body weight within 18 months to 2 years. However, up to 3 out of 10 gastric sleeve patients gain weight after reaching their low weight . The amount varies widely by patient, ranging from only a small amount of weight to
Surgical Skill and Complication Rates after Bariatric Surgery – Clinical outcomes after many complex surgical procedures vary widely across hospitals and surgeons. Although it has been assumed that the proficiency of the operating surgeon is an important.
Dr. Mathias Fobi shares if a patient’s stomach will continue to make acid after bariatric surgery and explains what will happen to the remaining stomach after gastric bypass surgery. It’s producing.
Jan 19, 2020.
A LAP-BAND® removal and revision to a better bariatric surgery, such as gastric sleeve surgery or gastric bypass surgery, can help many patients.
They can also revise a gastric sleeve with gastric bypass surgery.
in the U.S. We are proud to offer low-cost revision weight loss surgeries of virtually any type.
Revision procedure should ideally be performed by a highly trained and experienced bariatric surgeon with a successful track record of such procedures. During.
Can I Sleep On My Stomach After Gastric Sleeve Can I Take Nyquil After Gastric Sleeve Both are orange-colored (in contrast to their nighttime counterpart, NyQuil, which is green). While DayQuil is considered safe if used as directed, it can cause. With health care Flexible Spending Accounts, you can save on everyday items. taxes, it can help reduce your taxable income, increase your take-home
Insurance and Weight Loss – Did you know that some of your costs associated with the UC San Diego Health Weight Management Program may be reimbursed by your insurance plan? (See health insurance accepted at UC San Diego.) Weight.
Mar 6, 2019.
You have had your gastric sleeve surgery and started losing your weight,
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Jan 19, 2020.
Laparoscopic Loop Duodenal Switch (SADIS or SIPS). $19,610. Lap Band Revision to Gastric Sleeve. $13,300. Lap Band Revision to Gastric.

domain: medical


Honda S660 Bruno Leather Edition will be finally in production. Honda once caught people’s attention in 2013. It happened with the release of S660. However, the car was put in production in 2015. But this little roadster yet has more to render outside Japan. Well, it is just becoming more tempting. Honda S660 Bruno Leather Edition comes ultimately after long wait. As the name suggests, the car will be in brown. Moreover, it will consist of leather.
The model even has got a unique touch of paint exteriorly. And it is the Velvet Maroon Metallic paint. However, customers will have other options too. The car will be available in other colors. Owners can order it in metallic grey or pearl white. One can choose any one of them. However, the color must look perfect with the Brown leather cockpit. Moreover, the company will make only 800 models. It will be available with paddle-shiftable CVT or six- speed manual.
Honda S660 Bruno Leather Edition will even have a new feature at the same time. This is really very interesting. The car will feature an iPhone app. It is called as Rev Beat. It will shift six-speed in a game for the generation of Dance Dance Revolution. Moreover, the app rates every shift as Good, Excellent or Bad. It tracks the score of driver on the middle console display. However, the app will even permit sharing through Twitter. Well, we can just hope one thing. It won’t distract too much beyond the wheel.


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College Football: 10 Players Who Will Face the Dreaded Sophomore Slump in 2011
Each year, we see some very promising or down-right amazing freshman performances, and 2010 was no different.
But what happens when the novelty wears off? What happens when that promising young star, now a sophomore, is simply expected to perform at a high level?
No longer are these phenoms a pleasant surprise—they're now depended upon to be stars.
And when they don't meet the lofty expectations placed on them, we say they either have a slump, or worse, become irrelevant.
Here are a list of ten promising freshmen phenoms looking to avoid the dreaded sophomore slump.
Danny O'Brien, QB Maryland (FAA)
O'Brien had an impressive freshman campaign after taking over the starting duties for Maryland.
With limited playing time in the first three games, in which two of them he didn't attempt a single pass, he still managed to amass 2,438 passing yards and 22 touchdowns for the Terrapins.
After being named the ACC Rookie of the Year and a Freshman All-American, Maryland has certainly found a diamond in the rough in O'Brien.
When you have a quarterback that completes nearly sixty percent of his passes, and also has a touchdown reception to his credit, it's easy to put a lot of pressure on him to continue to perform at a high level.
Maryland definitely needs a star like O'Brien. The question now is can O'Brien continue to impress now that he'll be counted on to produce?
Marcus Lattimore, RB S Carolina
Marcus Lattimore was easily the best freshman running back in the nation in 2010, and he was named a Freshman All-American for his efforts.
The questions about Lattimore certainly have nothing to do with his talents or abilities, but rather if he can take the full weight of the Gamecocks offense on his young shoulders should starting senior quarterback Stephen Garcia not return for the 2011 season.
Lattimore is most effective when the defense is kept honest with the real risk of getting beat deep on a play action pass.
If Garcia doesn't return, South Carolina may lose that facet of their game, and that could seriously effect Lattimore's effectiveness.
Ronnie Hillman, RB SDSU
Hillman finished the 2010 season with 1,532 rushing yards, leading all freshmen in the nation.
San Diego State had a bit of a break-out season in 2010, and nearly made the national scene with a heart-breaking loss to TCU.
After SDSU lost their effective coach to Michigan, Aztec fans will definitely be looking to returning stars like Hillman to continue the recent successes at San Diego State.
Not only should Hillman, a 2010 Freshman All-American, respond well to the pressure, he'll be counted on to do so if SDSU has any chance in the Mountain West in 2011.
Josh Boyce, WR TCU
Josh Boyce, another Freshman All-American, had 646 receiving yards in 2010, averaging 19 yards per reception for the Horned Frogs.
Josh Boyce in one of a handful of returning offensive players for TCU, and with the massive talent drain the Horned Frogs are suffering through, players like Boyce will be counted on to make every pass thrown in their direction count.
TCU's last season in the Mountain West won't be an easy one, either. TCU has a conference road game at Boise State. It's been quite some time since a conference team went into Boise and left with a win.
TCU has one shot. Will Boyce and company be able to be one-hit wonders in Boise?
Robert Woods, WR USC
Right now, USC can use any good news that comes their way.
One very bright spot for the Trojans' future is Robert Woods.
This Freshman All-American wide out had 786 receiving yards in 2010, and also handled kickoff returns, amassing 971 yards on kick returns, including a touchdown.
Woods Is proving to be valuable both on offense and on special teams, and that's exactly the type of player USC will rely on to get through the lean years with reduced scholarship availability.
Woods will be counted on to step up his game in his sophomore season, and help USC climb back into the Top 25 in preparation for 2012, when they can once again compete for a bowl bid.
Xavier Rhodes, CB Florida State
Could there possibly be any more hype surrounding Florida State for 2011?
Part of the reason for all of the talk and the high preseason rankings is the talent that the Seminoles will have at their disposal.
One of the young, talented players suiting up for Jimbo Fisher is Xavier Rhodes, the young corner from Miami Norland.
Rhodes had 57 tackles in 2010, plus 3.5 tackles for loss, two sacks, four interceptions and 12 passes broken up.
Pretty impressive for a freshman—enough to get him named a Freshman All-American for 2010.
Rhodes is one of the players preseason pundits are looking at when they try to measure Florida State's potential for 2011. If Rhodes can take his game to the next level, it's possible Florida State could be every bit as good as advertised.
C.J. Mosley, LB Alabama
C.J. Mosley had a productive freshman campaign for the Crimson Tide in 2010.
While he only intercepted two passes in 2010, both of them were returned for touchdowns.
He also had 67 tackles, averaging over five per game.
He had 10 pass deflections, two QB hurries, and a half sack in his 2010 Freshman All-American season.
Alabama is highly ranked coming into 2011, and is expected to compete for both the SEC championship and a possible trip to the BCS title game.
It will be all hands on deck for the Tide, and Mosley will be expected to mature his game and increase his numbers for 2011. And if the Tide want to make a triumphant return to the BCS, they'll need Mosley to do just that.
Aaron Murray, QB Georgia
Passing for over 3,000 yards in the SEC is difficult enough. After all, Cam Newton didn't do it.
But when you're a freshman, that's down-right impressive.
Aaron Murray, the young star for the Bulldogs, had 3,049 yards in 2010, and 24 touchdowns.
While the 2010 season didn't start out as many Georgia fans had hoped, by the time the season was over, Georgia had a perfectly respectable record, and an emerging star in Aaron Murray.
Murray's task for 2011 is unenviable, however, as he'll not only be expected to avoid a sophomore slump, but be expected to be his teams leader as Georgia attempts to return to the top of the SEC-East.
Tyler Eifert, TE Notre Dame
Brian Kelly likes to utilize his tight ends. Freshman Tyler Eifert learned that first-hand in 2010, as he caught 27 passes for 352 yards and two touchdowns in 2010.
As Eifert gains experience and strength, he'll be expected to have more offensive output and the ball comes his way more often.
Notre Dame is also hoping for a return to national prominence—something that's eluded the Irish for the past decade or so.
Eifert will need to avoid a sophomore slump to not only keep his starting job at tight end, but also to help the Irish avoid the close losses that derailed their 2010 season.
Jimbo Fisher, Coach Florida State
Our last selection is a sophomore (of sorts) that will not only need to avoid a slump, but is expected to regain his school's past glory.
When first named as head coach for the Seminoles, Fisher said, “Empowered, confident athletes are winners. My goal is to get the structure, the staff, and the support resources in place to facilitate a winning plan, and get players into the structure and start effecting change. Now.”
Well, the “now” to which Fisher was referring is here, and the early picture looks pretty good.
Florida State is highly ranked in most early preseason polls, and is cracking the Top 10 in most of them.
It's no wonder, after a 10-4 first year, including a Chick-Fil-A Bowl win over SEC-East champions South Carolina. That performance was good enough for the Football Writers Association of America to name Fisher to their Freshman All-Ameican Team.
Fisher is expected to bring big things back to Tallahassee in 2010, and he'll definitely need to avoid a sophomore slump if he wants to keep the fans squarely in his corner.
If he does manage to improve on last season's success, he'll be well on his way to cementing his own legacy at Florida State.

domain: news


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As of 6:10 AM 06/3/15 All times are local (Market data is delayed by at least 15 minutes).
BOARD MEMBERS AFFILIATED WITH Jyoteendra M. Kothary *
Former Non-Executive & Independent Director, Chairman of Remuneration Committee, Chairman of Investors Grievance Committee and Member of Finance Committee
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*Data is at least as current as the most recent Definitive Proxy.
MOST CONNECTED PEOPLE TO Jyoteendra M. Kothary
Sponsored Financial Commentaries

domain: economics


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The value of total protein in guiding management of infectious parapneumonic effusion by using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
Chih-Yung Chiu, Sen-Yung Hsieh, Kin-Sun Wong, Shen-Hao Lai, Jen-Kun Chen, Jing-Long Huang
Received: July 18, 2013 Revised: October 25, 2013 Accepted: November 19, 2013
Jing-Long Huang, Corresponding author. Department of Pediatrics, Chang Gung Memorial Hospital, 5, Fu-Hsin Street, Kueishan, Taoyuan, Taiwan.
Background and purpose:
Infectious parapneumonic effusion (PE) contains proteins originating from circulation as well as proteins locally released by inflammatory pulmonary cells. The purpose of this study was to investigate the value of total protein analysis in guiding management of infectious PE by using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Fifty-seven children with pneumonia followed by PE were consecutively enrolled into our study. Protein profiles generated by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry after fractionating samples with functionalized magnetic beads (C8) were used for differentiating complicated PE (CPE) from non-CPE. A training set was used to generate classification models and the clinical efficacy of these models in detecting CPE and the need for intervention was then evaluated in an independent set.
The MS spectra derived from PE were analyzed, and classification models were constructed in the training set. A total of 123 mass/charge (m/z) values were identified and 23 m/z values which were significant with p < 0.05 were used as classifiers. An optimized genetic algorithm model containing enforced selection of three significant downregulated m/z values (2127, 2232, and 2427) was able to classify CPE with 100% positive predictive value and predict the need of aggressive therapeutic intervention with 77% positive predictive value.
A diagnostic model construction comprising three potential biomarkers can predict CPE and need for surgical intervention rapidly and precisely. Pleural fluid proteins downregulated during the progression of pneumonia could potentially guide the management of infectious PE.
Biomarkers, Complicated parapneumonic effusion, Surgical intervention


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The Gold Coast’s Sand Bypass System is about to receive a new lease of life with work underway on upgrading its high voltage switch gear.
We’ll invest about $1.9 million in upgrade works over the next 12 months.
The upgrade is expected to generate about 20 direct and indirect jobs over the life of the project.
Our CEO Hal Morris said GCWA has awarded a contract to engineering firm Cardno (QLD) to undertake design and procurement works and to oversee the installation of the upgrade.
‘The Sand Bypass System has been reliably pumping sand north and helping keep the Seaway open for boaties for more than 30 years, relying on the same high voltage switching gear installed back in the late 1980s.
‘It’s done a great job but it’s reaching the end of its natural life so it’s time for us to upgrade it in line with modern operational and safety standards.’
The Sand Bypass System is designed to transport 500,000 cubic metres of sand from The Spit to South Stradbroke Island each year. Ongoing improvements saw it pump more than 664,000 cubic metres along the coastline last financial year.
Mr Morris said the upgrade builds on other investments in improving the operating efficiency of the system including a project to strengthen the jetty decking which is nearing completion and the installation of a solar array which is producing enough energy to help meet the day-time needs of the Sand Bypass System.
The high voltage upgrade will also support the City of Gold Coast’s Sand Backpassing project which proposes to connect a pipe into the Sand Bypass System to pump sand south to the beaches around Surfers Paradise to build resilience to storm surges and erosion.
The contract awarded to Cardno is worth just under $175,000 and is included in the $1.9 million investment planned for the next 12 months.


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00032040 btc to usd
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The Horned Violet appeared on the territory of our country in the eighteenth century. It is surprising that its popularity only grew and now it occupies the first places in the list of the most famous ornamental plants. Nowadays, plant breeders are actively cultivating this herbaceous plant in their living quarters on the windowsills.
Violet Horned - description and characteristics
This herb is considered a plant that has been growing for several years; it is considered to be in the Violet family. In common people, you can hear how the violet is called viola, because the word itself is translated from Latin as "Violet". In height, the herbaceous reaches from eight to twenty-four centimeters, this is directly influenced by the variety of the plant. Flowers in a single copy have an unobtrusive smell, and also slightly elongated petals, similar in appearance to small moths. The herbaceous diameter can reach up to five millimeters. They are placed on petioles. The foliage of the plant has a bright greenish color and the shape of a regular oval, there are small jagged edges.
In addition, this herbaceous plant has a fairly developed root system, which grows rapidly. In about twelve months, a couple of bushes will be able to occupy an area of two square meters. All the bushes have a large number of flowers, some varieties have sixty copies. So, in the process of flowering, the bush is transformed into a large blooming mound.
On the back of the buds and flowers there is a small growth that resembles a horn in appearance, so this representative of herbaceous crops also bears the name "Violet Horned".
Plants differ in a rather long flowering process, which lasts from the first week of the last spring month and ends in the last weeks of the second autumn month, but the most magnificent and beautiful flowering process for a plant is in the spring season. In the summer season, and especially on hot days, the flowers decrease in size, but by the autumn season they return to their usual appearance.
The color of this representative of herbaceous crops has a large palette. Flowers come in one color, two or three. Stop your choice depending on your preferences. For example, it is possible to get a delicate lilac or bright orange color, or opt for a velvet purple look.
Violet Horned: varieties
There are many species and subspecies of this representative of herbaceous crops, the differences of which are mainly in color.
This variety feels great in kindergartens. The bush grows up to ten centimeters up. It is covered with a mixture of white and red colors, and their number reaches fifty-five copies. The flowering process continues from the last spring month to the first autumn month. Usually, this representative of herbaceous crops is used to decorate alpine slides or plant them near curbs.
It is recommended to cultivate this herbaceous in a partially shaded place in which the land will be fertile. In height, the shrub most often does not reach more than fifteen centimeters, and its stems can form compacted pads.The flowers are quite large in size, with a reddish color, therefore this variety is sometimes called "Ruby Perfection". In addition, the flowers have the shape of a regular circle. A small bush can grow up to forty - fifty flowers.
This representative of herbaceous crops is usually used to decorate loggias or gazebos. The flowers are quite small, up to three centimeters in diameter, and can bring joy to flower growers throughout the summer season, and even during May. Herbaceous includes a fairly small bush and can withstand frost wonderfully. In one area, this plant can grow up to four years.
- "Gzhel patterns".
The plant acquired this name because of its pattern, which looks like Gzhel. The bush grows up to eighteen centimeters and beautiful violets are formed on it, the color of which is white and blue. The flowering process continues from the last spring month to the first autumn month. Quite often, the plant is used in a variety of compositions, for example, in the manufacture of alpine slides.
This representative of herbaceous crops is very beautiful, striking with a specific combination of colors. The flowers of this plant on each bush can be snow-white and orange at the same time. The herbaceous itself is rather small, up to ten centimeters up, but in the process of flowering the plant transforms into a flowering carpet. At one moment, up to sixty flowers can grow on a bush.
- "Erlyn F1".
This representative of herbaceous crops is quite resistant to cold weather. It grows small, up to ten centimeters. The flowers have a regular heart shape, and their color is purple with a yellow spot in the middle. Quite often, in addition to decorating flower beds, the plant is used in garden containers.
In addition to the above varieties, it is necessary to mention:
- "Edmaer maxi mix".
- "a penny".
- "Cheerful family".
Violet Horned: landing
For the cultivation of this plant, the seed method of planting directly into the fresh air or the seedling method is used. The choice of method depends on the preferences of the grower and their employment.
- Seedling method
Using this method, it is possible to plant from the last winter month. If this process is performed earlier, then the formation of flowers will be much earlier. For this, fertile soil is useful, which can be bought in all flower supermarkets or made with your own hands. In both cases, the soil must be heated in an oven before planting, and also treated with a foundation solution. This will reduce the risk of contracting fungal diseases.
After preparing the soil, it is necessary to make shallow pits in it and place seeds in them. The space between them should be at least one and a half centimeters. Then the seed material must be covered with soil and moistened using a sprayer.
After that, the container must be covered with a film and moved to a place where the temperature regime will be no more than seventeen degrees. At higher temperatures, seed adaptation is impaired. When the first shoots appear, the containers must be moved to a place with sufficient sunlight, where the temperature should be twenty-one degrees. With the formation of four leaves, it is possible to make seating in separate containers. The space between young seedlings should be at least six centimeters.
It is possible to plant a herbaceous plant in fresh air in the first week of the last spring month.
- Into the fresh air
To cultivate this plant with this method, seed material must be planted from the first week of the last summer month to the second half of the first autumn month.It is recommended to use new seed. Planting is done in the same way as seedling. When the seedlings gain strength, they can be planted in a permanent place. When flowers form, they must be removed so that the herbaceous does not waste energy, which is so necessary in the winter season. For the next spring season, this representative of herbaceous crops will delight you with the flowering process.
Violet Horned: care
This herb does not require special agrotechnical means, therefore its cultivation does not require a lot of time. It grows on all types of land and is rather quickly divorced. It is recommended to plant the plant in partially shaded or sunny places, but only in the presence of tall grassy ones. When plants are planted in a fairly shaded area, the herbaceous plants will become smaller in size.
Moistening of these herbaceous plants should be in moderation, due to the excellent transfer of especially hot days by the plant, but with excessive drought, the flowers are crushed. The growth of this plant will also stop.
This means that on especially hot days, if there is such an opportunity, it is necessary to spray the grass in the morning and evening hours.
It is worth remembering about feeding. It is necessary to place them in the soil twice a season, namely in the spring, in the process of active growth, and at the end of the summer season. It is possible to use both mineral and organic fertilizing. When using organic feeding, only humus should be placed, but not fresh mullein. With this option, the herbaceous can burn.
It is necessary to prune the bushes, because they grow rapidly, and they lose their beautiful appearance. It is also necessary to remove all wilted flowers, if there is no desire to collect seeds. This plant withstands the winter season well, because it does not tolerate cold weather, but young herbaceous plants must be covered using fallen leaves or spruce sticks.
Violet Horned: flower reproduction
It is possible to breed this plant simultaneously by several methods, which will be presented below.
- By dividing the bush
This method is quite easy and accessible to everyone, including a person without experience in gardening. Herbaceous must be removed from the soil and divided into small parts. All parts must have roots. Then plant the pieces in moist soil in a partially shaded area. These bushes take root within fourteen days.
This breeding is possible from the spring season to the second half of the summer season.
- Using layering
Also a simple breeding method. It is enough to find a single or group shoots and simply attach them to the soil using an object of your choice, for example, an invisible hairstyle. These places are then covered with soil and moistened as needed. After thirty-one days, roots should form, which can be transplanted to a permanent site.
- Using cuttings
Cuttings can be cooked from the first week of the first summer month to the first week of the second summer month. Their length must reach at least five centimeters and have two knots. Then they must be planted in containers with pre-prepared soil and placed one centimeter deep. Then it must be covered with a film and placed in a warm room. Sometimes it is necessary to moisturize them. After thirty-one days, roots should form, then young grassy ones can be transplanted to a permanent site.
Diseases and pests
Among the many diseases that are often found in this plant, the following should be highlighted:
- Powdery mildew.
- "Rot is gray".
- "Rot brown".
- "Black stem".
If diseases were detected at the very beginning of development, then herbaceous ones still have a chance of salvation.For this, specialized chemical agents are used, but if you have not noticed how the disease was formed, then it is worth discarding the affected herbaceous ones.
This representative of herbaceous crops often suffers from aphids and slugs, as well as violet mother-of-pearl. To get rid of these parasites, it is possible to use methods from the common people, as well as chemical preparations. The most effective folk remedies:
- spraying with potato peel solution.
- spraying with tobacco solution near the bush.
- spraying with onion solution.
Application in landscape design
This plant is perfect for cultivation in gardens, in hanging containers or for making beautiful alpine slides. Usually the plant is planted in small groups. If the planting of large herbaceous plants is meant on a flower bed, then the herbaceous plant must be planted in the foreground.
- In the curbs
By planting this plant near the sidewalk, it is possible to enjoy the plants during the summer season. Apart from this, it is possible to add various herbal ones.
- In suspended containers
Plants look great in wonderful pots, you can hang them on the loggia or veranda. In addition, with this method it is possible to decorate the courtyard, garden and gazebo.
This stunning herbaceous, as this representative of herbaceous crops, is perfect for cultivation both in summer cottages and outside the city.

domain: biology