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For most people, an assisted living facility is probably not the first place that comes to mind when thinking of a venue to spend a warm, sunny summer afternoon with friends. Melissa Green, Executive Director of Journey Senior Living, hoped to change that mindset.
"We do our best to do unique events to bring people into our building," Green said. "We welcome everyone to come and check us out."
And it worked. Friday afternoon, the front lawn of Journey’s Valparaiso location overflowed with a mix of residents, their families, and members of the extended community of all ages, gathered together for their BBQ and Blues summer concert event.
"I've been counting down the days,” Green said. “I'm really excited about it. I just thought [is was] an awesome idea to have some barbecue, listen to some Blues music. Who doesn't like Blues?"
The live music was provided by local band The Blues Project, the brainchild of music educator and group founder Scott Cvelbar and his wife Mary Cvelbar.
The Blues Project, explained the Cvelbars, brings kids together to learn Blues and Jazz playing styles and history.
"Hopefully I can expose them to some of that fantastic classic music that they can use to build their own musical careers," said founder Scott Cvelbar.
The group plays music around the community, helping to build confidence and provide opportunities to play with other musicians and play different venues.
“I think it's a really great idea especially for our kids that are playing music with us that they kind of get to integrate with different parts of the community," said Mary Cvelbar, who also serves as Mix Master for the band. "It feels fabulous to be a part of a day involving so many different ages of people enjoying all of the same things."
A nurse by trade, Mary Cvelbar said she has been very impressed with the facilities and staff at Journey.
"So far I've never seen a more organized place, the way that each of the workers here were engaging with the residents," she said.
Sharon Browne, attending the event with her mother, and Journey Senior Living’s very first resident, Dolores Browne, agreed wholeheartedly.
"We're really happy with it,” Browne said. “[Mom] loves it. She's got a beautiful apartment and they have a lot of nice functions."
Valparaiso local Angie Monahan attended the event with her husband Frankie.
"We're here supporting the community and enjoying the music and food," Monahan said. “It's a beautiful facility. Everyone pitches in to make it really wonderful for their residents here.”
Next week on Wednesday, June 19, Journey Senior Living of Valparaiso will be hosting the Winamac Old Auto Club Car Show in their parking lot from 11 A.M. to 2 P.M.. Admission is free but RSVPs are requested. For more information about the show and other upcoming events, please visit their website at http://www.journeyseniorliving.com/valparaiso/.


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ELENCE TWIN SCALP SHAMPOO EX-3 (CURLY/FRIZZY HAIR)
Lengthening shampoo for hair and scalp.
Elence Premium 2001 Twin Scalp Shampoo EX-3 is made for individuals with frizzy, curly, and wavy hair. This specific formula will straighten your hair, giving you a smoother and sleeker look while supporting the appearance of healthier, fuller, and longer looking hair in the shortest time possible.
- Contains 30 herbal extracts to moisturize and rejuvenate scalp and hair
- Supports the appearance of longer and fuller looking hair
HOW TO USE
Shake well before use. Massage into wet hair and scalp, rinse and repeat if desired. Follow with Elence Premium 2001 Twin Scalp Hair Pack EX-3.For maximum lengthening results use our Elence 2001 Scalp Essence EX-3 after using shampoo and hair pack.
Precautions: For external use only. Avoid contact with eyes. If irritation or sensitivity occurs discontinue use and consult a physician.
aqua (water/eau), sodium laureth sulfate, sodium c14-16 olefin sulfonate, ethylhexyl palmitate, cocamide dea, alcohol denat., lauryl betaine, butylene glycol, PPG-9 diglyceryl ether, sodium cocoamphoacetate, polyquaternium-10, sodium chloride, phenoxyethanol, steartrimonium chloride, fragrance/parfum, octyldodecanol, maltitol laurate, caramel, isopropyl alcohol, citric acid, sodium benzoate, dipotassium glycyrrhizate, propylparaben, betaine, methylparaben, alcohol, etidronic acid, acetyl cysteine, olea europaea (olive) fruit oil, hydrolyzed collagen, hydrolyzed keratin, hydrolyzed wheat protein, glycerin, citrus unshiu peel extract, sophora angustifolia root extract, paeonia suffruticosa root extract, panax ginseng root extract, swertia japonica extract, isodonis japonicus extract, eriobotrya japonica leaf extract, chamomilla recutita (matricaria) flower extract, malva sylvestris (mallow) extract, rosmarinus officinalis (rosmary) leaf extract, glycogen, betula alba bark extract, glycine soja (soybean) seed extract, rehmannia chinensis root extract, paeonia albiflora root extract, cnidium officinale root extract, angelica acutiloba root extract, arnica montana flower extract, equisetum arvense extract, hypericum perforatum extract, achillea millefolium extract, salvia officinalis (sage) leaf extract, calendula officinalis flower extract, tilia cordata flower extract, hydrolyzed conchiolin protein, anthemis nobilis flower extract, lamium album flower extract, nasturtium officinale extract, arctium lappa root extract, pinus sylvestris cone extract, hedera helix (ivy) extract, allium sativum (garlic) extract.

domain: health


Ziwani-based, Team Umeme shared spoils with visiting Zamalek FC after playing to a barren draw at Ziwani grounds at the weekend in one of the Super Eight Premier League matches.
Umeme who started the match as hot favourites on paper, failed to find the back of net despite dominating most of the action. Fans who had turned out in large numbers went home rather disappointed after the match they had eagerly anticipated to produce a glut of goals failed to live to its billing.
After the draw, Umeme found themselves lying at 11th position with 22 points while Zamalek dropped one position down on the 16-team log to settle for fourth place with 34 points where they tie with Jericho FC but with an inferior goal difference.
Elsewhere, at Kabete ACK grounds, hosts Kabete United held champions Kayole Asubuhi to a 1-1 all draw. Asubuhi netted their goal through Tobias Olum while the hosts leveled the scores through their marksman Mafuvi Williams.
Kabete are currently placed 10th in the log with 23 points while Asubuhi, who have started the second leg on rather slow pace, are fifth with 29 points, 16 below leaders Kawangware United.
At Nakeel grounds in Rongai, visitors Meltah Kabiria white-washed hosts Ole Rongai formerly Diguna FC 3-0 in a one-sided match. Meltah scored through Edward Njue, Vurugu Evans and Sammy Agesa to move to eighth position on 27 points.


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This mineral species can be opaque to crystalline transparent. The color of lazulite ranges from medium to dark greenish blue to violet blue and is often mottled with white. When fashioned into gems, finished stones typically weigh less than 5 carats. A separate mineral species, lazulite should not be confused with lazurite or azurite.
- Optical Properties
- Characteristic Physical Properties
- Chemistry & Crystallography
Countries of Origin
Myanmar; Afghanistan; Russian Federation; Czechia; United States of America; Madagascar; United Kingdom of Great Britain and Northern Ireland; Portugal; Austria; Sweden; Pakistan; Morocco; Unknown; China; Ireland; Brazil; Slovakia; Bulgaria; Chile; France; Argentina; Hungary; Japan; Rwanda; Switzerland; Bolivia (Plurinational State of); India; Spain; Canada; Norway; Namibia; Finland; Italy; Zimbabwe; Antarctica; Australia; Peru; Germany
Gets its name from the German word "lazurstein" which means blue stone.
Lazulite is brittle so please handle with care. It is slowly soluble in acid in hot acid.

domain: chemistry


Published 05. Dec. 2018
Driving Into a Low Emissions Future – Looking beyond 2021
Michael Schweikl, Automotive Expert, PA Consulting
Minds are increasingly focused on the European Union (EU) 2021 CO₂ emissions targets. That means car makers face some difficult choices about their future direction. As PA Consulting’s (PA) latest analysis shows, some car makers have got their strategy right and will meet their targets easily, but others have woken up too late and will struggle. While many of these late risers have plans for new low emission models, it will be hard for them to implement their plans fast enough in the next three years to make a real difference in meeting their targets. Those companies at risk of missing their targets will need to prioritise the selling, marketing and pricing of these vehicles to counter negative perceptions in the market.
EU CO₂ emissions regulations are the most stringent in the world. Each car maker has a specific target for their registered car fleet in 2021. The aim is to have a European average of 95 grams of CO₂ per kilometre. Car makers face penalties of €95 for every gram of CO₂ they are above their limit, multiplied by the number of cars they registered in the EU in the previous year. The industry is also facing a range of other challenges such as the prospect of city bans for internal combustion engines, the dramatic decline of diesel and the boom in SUV sales.
This is the fourth year PA have assessed car makers’ performance and the likelihood that they will meet their 2021 targets. The reality is that given the proximity of the 2021 deadline, and the lead-time needed to implement technical changes, there’s little they can do in time. However, car makers are already at work on technical upgrades to meet the 2025 and 2030 targets. So, for now, they’re essentially running two parallel processes: working to build market share for new low emission models before 2021 while investing in the technology needed to meet future regulations until 2030.
This unique method of benchmarking by PA examines manufacturers’ performance against their specific targets and evaluates the gap car makers will need to close by 2021. Forecasts are made up of an assessment of each manufacturer’s capability to reduce average fleet weight as well as to enhance their electrified portfolio. PA also make forecasts of the number of registrations of each type of car (diesel, petrol, different types of hybrid and battery electric) to determine the extent of each manufacturer’s sales of lower emission vehicles. This year, we have looked at sales of these vehicles by vehicle segment (from small to luxury cars) which has helped us make our forecasts more accurate.
This year’s rankings show eight out of the thirteen car markers forecasted to miss their targets, though some are getting closer by accelerating towards their 2021 targets relative to how fast they’ve gone in previous years. Toyota is now at the top of the table followed by Renault-Nissan-Mitsubishi and Volvo, Daimler and BMW have improved their performance and are getting closer to complying. What this means is that some companies are likely to face significant fines. Volkswagen faces a potential penalty of 1.4 billion Euros (10 per cent of its 2017 earnings), reflecting the high number of cars they sell in Europe. PSA (including Opel/Vauxhall) could see fines of 600 million Euros, amounting to 20 per cent of its earnings in 2017, and Ford and Fiat Chrysler (FCA) could see penalties of 10 per cent of their earnings in 2017.
Our results show that it’s too late for dramatic changes in technology or strategy to make a difference to manufacturers’ ability to meet the 2021 targets. This underlines that those manufacturers at risk of missing their targets need to focus on sales, marketing and price. Only by increasing their sales of low emission vehicles will they be able to move towards the target and reduce their fines. That means focusing and understanding their sales volumes by CO₂ emissions, underpinned by marketing that really pushes hybrids and fully electrified vehicles. There’s also the question of price. When it comes to electric vehicles, it will take until 2028 for them to cost the same as conventional petrol ones, so manufacturers may need to take the profit hit by providing price incentives to generate enough sales to make a difference. However, the car industry has always been a hugely innovative one that has been able to respond to challenges and with the right strategy it can prosper even in an uncertain future.


Blanking Panels and Rack Airflow Management
Improving rack airflow plays an important role in data centre airflow management. By preventing hot server exhaust air from recirculating back to the front of the rack, and mixing with the cold air cooling the servers, can efficiently improve their cooling and help make energy cost savings.
One major part of this is the use of Blanking Panels which play an important role in the airflow efficiency of the data centre. Blanking Panels are used to seal off unused rack space and EDP Europe offers Blanking Panel solutions which includes HotLok®, EZIBLANK® and PlenaFill®. EDP also offers other products that prevent air from recirculating between the rails and side of racks and underneath the rack, as well as replacement floor tiles with pre-cut cable openings sealed with brush strip.
EZIBLANK® Blanking Panels are 6U blanking panel sheets that are scored at 1U intervals and are a part of a series of airflow management solutions from IDC Solutions, that are distributed in Europe by EDP Europe. As well as the EZIBLANK® blanking panels the other solutions include: EZIBLANK®42 a full rack height rack blanking solution, EZIBLANK® WALL a rack replacement panel and EZIFLUTE™ and underfloor airflow control panel.
PlenaFill® blanking panels are supplied in packs of 10 27U sheets, that's 270U of blanking in one pack! Each PlenaFill® 27U sheet is scored at 1U intervals so the required number of U can be simply snapped off.
AisleLok under rack panel is designed to seal openings below the rack on new and existing raised server racks, the AisleLok under rack panel blocks bypass airflow and maximises the cooling system's efficiency.
EDP Europe offer replacement floor tiles which have openings already in them that are sealed with brush strip grommets. These replacement floor tiles provide greater flexibility and efficiency, enabling data centre managers to speed up cabinet deployments, whilst optimising cooling performance.


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domain: economics


text:
The new UltraFICO credit score is coming in early 2019, and it's bringing big changes. But homebuyers who put off buying a house may be.
First Time Home Buyer Bad Credit Texas Get FREE money with first time home buyer programs in Texas!. Home Sweet Texas is a home loan program for low and moderate income Texans.. Mortgage credit certificate (mcc) can help you save up to $2,000 every.
What is a good credit score if you want to buy a house? If you want to know what your chances are of securing a home loan you’ll want to know what is a good credit score in South Africa to gauge your chances of a successful application.
At this time, there are no updates published for 2019 but it’s always wise to work with an FHA lender who can keep you up to speed on the latest policies. Right now, the minimum credit score to.
Editor’s note: The 2017 changes are still in effect in 2019.According to Ellie Mae, more lower-credit FHA applicants are being approved. In July 2016, only 19% of closed FHA loans were for borrowers with a score of 600-649; by December 2017 that increased to 23.6%.
For this, you need to check your credit and fix any errors. “Improve credit score to buy a house” by paying down your credit card balances. check your savings to see if you can pull some extra cash to.
There are many misconceptions about the credit score needed to buy a house. Recently, it was reported that 24% of renters believe they need a 780-800 credit score to be considered for a mortgage. The reality is they are misinformed! Only 25% of the Americans have a FICO Score between 740 and 800.
First Time Home Owners Loan With Bad Credit Current Mortgage Rates For First Time Home Buyers That’s because mortgage rates are generally tiered, and typically lower mortgage rates are available for those with a down payment of 20% or more. If possible, consider increasing your down payment to see if it’ll get you a lower rate for your home loan. Improve Your Credit Score. Your credit score is one of the biggest factors that affects the.How Much Down Payment For First Home Down Payment: How much you should save to buy a home – First. – Is buying a home on the horizon for you? Have you started to save up for the down payment? Let's first start with the basics of what a down payment is. A down .Home equity loans with bad credit ; Insurance.. Buying your first home comes with many big decisions and can be as scary as it is exciting.. Here are the 14 most common mistakes first-time.
Credit Simple chief executive david scognamiglio said they’re "pretty meaningful" because credit ratings or scores could be.
Mortgage Criteria For First Time Buyers Mortgage Loan Options for First-time Buyers. First-time homebuyers may want to consider choosing a loan program specifically designed to help get you into a home with a smaller down payment. Many first-time buyers are interested in loan options that allow them to purchase a home with 3.5% down, such as FHA or Fannie Mae loans. fha loans. fha loans help first-time buyers purchase homes by offering government insured loans with more lenient qualifying guidelines such as lower down payment.
But the company recently took bold business steps to become both a mortgage lender and house flipper. Last April, Zillow.
The minimum credit score needed to buy a house using an FHA loan is 500-580. VA loans may accept a 580 score as well. USDA and 203k require 620-640.
First Time Home Buyer Program Requirements Zillow Grand Prairie Tx The real estate investment firm acquired similar type apartment communities in Flower Mound, TX, and Grand Prairie, TX, in a $100 million portfolio deal from a San Antonio-based seller in December.Thinking about buying a home? We have information that can help! Got questions? Talk to one of our housing counselors! Need Help? 1. Figure out how much you can afford. What you can afford depends on your income, credit rating, current monthly expenses, downpayment and the interest rate. home economics; homebuying programs in your state
Credit scores are another important requirement to buy a house in Oregon. These three-digit numbers give lenders insight into how you have.
But what credit score is needed to buy a house? You’ll need at least a 500 FICO credit score to qualify for a Federal Housing Administration loan, but other programs may require a 620 FICO score or.
What kind of credit score do I need for a Mortgage Loan Approval in Kentucky in 2019? Kentucky Credit Score Requirements for Conventional, FHA, VA, USDA.

domain: finance


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Top Tips for Winter Plant Protection
With a little preparation and some frost protection essentials there’s no reason your plants can’t thrive this winter.
As shorter days & colder nights approach, take some time to prepare to protect your outdoor plants from the first frost. Try to move any smaller or potted plants to sheltered spots. A Frost Protection Jacket will also provide your plants with further protection.
Our specially designed plant frost jacket is made from extra thick material to protect against temperatures as low as -8°C, but still permeable enough by air, light and moisture to ensure healthy plant growth. The winter sun will warm the air inside the jacket, which will also retain any heat.
Protecting Larger Plants from Frost
For those of you growing fruit trees, palm trees or cordylines, Gardening Fleece, also known as a horticultural fleece, is a highly effective form of plant frost protection. Wrapping garden fleece around the crown and trunk is ideal for protecting it from the bitter winds and harsh cold whilst allowing the plant to absorb water and nutrients for healthy growth.
Without sufficient frost protection, the water inside your plants’ cells will freeze overnight, damaging the cell walls. When the sun rises in the morning, the suns warmth will quickly defrost the cells and risk rupturing the cell walls altogether. This can take its toll on your plants gradually, or the shock could rupture the cell walls instantly.
Top Frost Protection Tip!
Brick walls will help to shield your plants from the harsh winter winds and, more importantly, absorb heat during the day, releasing it overnight, providing further heating for any nearby plants; making this an ideal spot to relocate prized plants. For additional frost protection our Gardening Angels love this clever Wall mounted Greenhouse.
If possible, you should position your plants at a higher point in your garden as it will minimise damage from sinking cold air. Whilst hearty foliage will not need to be covered, should you experience any snowfall, try to keep as much snow as possible off the branches as the extra weight can cause damage over time.
Provide seedlings with added protection from cold weather with a heated propagator, perfect for creating a frost free growing growing environment, encouraging your seedlings & young plants to flourish in a safe, temperature controlled miniature greenhouse.
If your using a Vitopod Heated Propagator, plan ahead and add add extra layers to this height adjustable propagator. Perfect for keeping mature, taller plants frost free over winter until outside temperatures begin to increase again and ideal for giving your plants extra room to grow!
If you would like to find out more about frost protection or propagation, feel free to drop us an email at firstname.lastname@example.org. Our Gardening Angels are always happy to help and we’d love to hear about how you get on this winter!

domain: biology


text:
On some days, we want to escape the busy city hustle!
In today’s busy city life everyone seeks time to get disconnected to go spend some time with nature. The first thought remains of freeing oneself from the noise and pollution and finding some place where one can calm their restless mind and anxious heart.
A Luxurious Tarangi Resort & spa offers a bunch of activities to get closer to the nature.
Established in 1936, Jim Corbett is India's first national park. It was first named the Hailey National Park after William Malcolm Hailey during the British Raj. Following India's independence, it was renamed Corbett National Park in honour of Jim Corbett, a naturalist, and hunter who was instrumental in its establishment.
This is where we sit down, grab a cup of coffee and dial in the details. Understanding the task at hand and ironing out the wrinkles is a key point.

domain: travel


Parallax use For Stanley Meyers Systems
Why I use Parallax Propeller chip instead of Atmel or Arduino for my software projects
here you find a brief compilation of my arguments for the Propeller uC chip integrated into laboratory equipment:
Now PGen Version 2.0 also supports as a new advanced feature phase shift and lock control for up to 4 channels in a single uC.
You can run each channel independently or bind 2 to 4 channels together so that their pulsing scheme is synchronized.
phase shift can be exacly modified in realtime for each individual channel. each channel can have completely different designed pulsetrains with or without gating, different duty cycles, different pulse repetition rates and as long as total pulsetrain length is equal those channels will stay locked towards each other.
if you make slight changes in pulsetrain length for a channel you can easily create controlled floats of pulses between those bound channels.
total pulse train length is monitored and displayed for each channel and between channels so that it´s easy to adjust timing for each channel to make sure that pulselength stays the same.
for all those adjustments you not even need a scope because the control information is displayed by PGen.
This complex feature gives total control i.e. for the Gas Processor EEC vs. high voltage pulse and led pulse control, railgun, Bob Boyce applications, magnetic gas applications and many others.
For more information http://www.source-for-innovations.com
Quick info -
There is a special PGen package offer avaliable by Innovationsshop to support free energy project developers for a full featured single channel PGen solution. It´s exclusively software at $20 and not listed at Innovationsshop´s pricelist.
it can be set against later channel upgrades.


Everything About CSE Notification, 2018 By Yash Aaditya Singh
About Me e Electronics And Communications Engineer From IET, Lucknow(AKTU) CAT, XAT, NMAT And CDS Qualifier. International Youth Maths Contest(IYMC) Maths Olympiad(World Level) Bronze Medalist Enthusiastic About Debating And Speeches. Bibliophile. Budding Photographer. And Now A Teacher..)
Vacancies The number of vacancies to be filled on the result of the examination is expected to be approximately 782 which include 32 vacancies reserved for Persons with Benchmark Disability Category, i.e. 13 vacancies for candidates of (a) blindness and low vision; 8 Vacancies for (b) deaf and hard of hearing; 9 Vacancies for (c) locomotor disability including cerebral palsy, leprosy cured, dwarfism, acid attack victims and muscular dystrophy; and 2 Vacancies for (e) multiple disabilities from amongst persons under clauses (a) to (c) including deaf-blindness.
Vacancies The final number of vacancies may undergo change after getting firm number of vacancies from Cadre Controlling Authorities. e Reservation will be made for candidates belonging to Scheduled Castes. Scheduled Tribes, Other Backward Classes and Persons with Benchmark Disability in respect of vacancies as may be fixed by the Government.
Vacancies As per the decision taken by the Government for increasing the access of unemployed to job opportunities, the Commission will publicly disclose the scores of the candidates (obtained in the Written Examination and Interview/Personality Test) through the public portals. The disclosure will be made in respect of only those candidates who will appear in the Interview/Personality Test for the Civil Service Government strives to have a workforce which reflects gender balance and women candidates are encouraged to apply. Examination and are not finally recommended for appointment.
Vacancies The information shared through this disclosure scheme about the non-recommended candidates may be used by other public and private recruitment agencies to appoint suitable candidates from the information made available in the public portal Candidates will be required to give their options at the time of Interview/Personality Test, while acknowledging the e-summon letter mailed to them for interview. .
Vacancies A candidate may opt out of the scheme also and in that case his/her details will not be published by the Commission Besides sharing of the information of the non-recommended candidates for the examinations conducted by the Commission, the Commission will not assume any responsibility of liability for the method and manner in which information related to candidates who appear at the Commission's Examinations/ Selections is utilized by other private of public organizations.
Centres Of Examination(Prelims) AGARTALA GHAZIABAD GAUTAM BUDDH NAGAR AGRA GORAKHPUR PANAJI (GOA) AJMER GURGAON PATNA
Centres Of Examination(Prelims) AHMEDABAD GWALIOR PORT BLAIR AIZAWL HYDERABAD PUDUCHERRY ALIGARH IMPHAL PUNE
Centres Of Examination(Prelims) ALLAHABAD INDORE RAIPUR ANANTPUR (ANDHRA PRADESH) ITANAGAR . RAJKOT AURANGABAD JABALPUR RANCHI
Centres Of Examination(Prelims) BILASPUR JORHAT SILIGUDI CHANDIGARH KOCHI SRINAGAR CHENNA KOHIMA THANE
Centres Of Examination(Prelims) DELHI LUDHIANA UDAIPUR DHARWAD MADURAI VARANASI DISPUR MUMBA VELLORE
Yash Aaditya Singh
Electronics And Communication Engineer From IET Lucknow, IYMC Maths Olympiad Bronze Medalist, CAT,XAT And CDS Qualifier, Active Debater


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View of the Shindagha district from Dubai Creek. In the foreground a small boat and a large, heavily loaded dhow (sailboat) are beached in the sand. Nearby piles of coral, used for building houses, lie on the shore and a number of people walk across the sand. In the left distance a large enclave of 'arish huts and enclosures made from palm fronds sit in the sand. In the central distance a square stone watchtower, the Shindagha, rises high above nearby buildings. In the far right distance, on the far side of the creek, one and two storey houses are built close together in the Shindagha district.
Due to the nature of these images, prints will reproduce any signs of age, wear or damage that occurred before they were archived by the Pitt Rivers Museum.

domain: geography


text: Usually, it’s the mix of prints and textures that really makes the dress stand out. Tuko.co.ke News ☛ ★AFRICAN DRESSES★ are becoming popular day by day. The latest Ankara long gown styles for wedding occasion, and African Print Styles. We all love weddings yes! Colorful Prints. African print styles for weddings. . African Wax Print Ankara V-Neck Midi Dress Suit Office Style for X11076 Item Type: Africa ClothingSpecial Use: Traditional ClothingGender: WomenMaterial: CottonType: Top and SkirtsItem Type: African ClothingFabric: Wax/BatikPattern: PrintSpecial Use: Traditional ClothingType: Dashikiis_customized: Yesis Lining: YesOccasion: Wedding,Party,CasualStyle: Top and Skirts Here we share some of the ideas of African Print Dress Styles For Weddings 2020 for the bride because this is her special day which never comes in their life again. African print skirts and tops. 5 out of 5 stars (8) 8 reviews We have rounded up 2021 African Fashion and Trending Ankara Styles Causing A Stare Right Now. Required fields are marked *, African Print Dress Styles For Weddings 2020, African Print Dress Designs For Weddings 2020. Check out our african wedding dress selection for the very best in ... African women's wear,African print prom dress,african wedding dress,african clothing for women,long african ... African couple wedding suit, African couple outfit, Nigerian couple dress, Ankara styles TeeTeecollections. Your email address will not be published. L'AVIYE's African print dresses & ankara dresses are guaranteed to make a statement. Who says bold African prints can’t hold their own in a corporate environment? Some of the brides do go for the Mermaid Style dress too with the African print. ALSO READ: 25 Gorgeous Natural Hairstyles to […] If you are an African girl then believe me just try this White wedding dress once it will look fabulous on you. African Mixture of Color and White Dress: In the African Print Dress Styles For Weddings 2020, you also have seen some of the mixtures of the Color dress with the White Dress as some of the Pictures are shared below. As you wedding is just after a few hours then let us help you in choosing the perfect Outfit for you that suits your personality and make your day more beautiful and attractive. For women’s African attires, you will find handmade African print skirts, African print tops and jackets, African dresses, African print trousers, Wrapper skirts, dashiki tops and much more. Step out in style as couples in this amazing Ankara hand made dress, show your love for each other wherever you go, … Well, you can see that in our latest Asoebi styles set will do right to your needs. So if you are looking to slay for that wedding, then check out these awesome looks we have curated for you and get inspired! This color is most favorite because the texture and the mixing of this color make the dress more attractive as you can also see in the pictures below. This dress is one of the traditional African Print Dress Styles For Weddings which is used by most of the brides even these days. Jun 24, 2020 - Asoebi and Ankara styles for kimono, jumpsuit, peplum for gown and skirt and blouse for wedding, parties, events owambe See more ideas about african dress, african clothing, african fashion. colourful Toghu traditional fashion wears The cool patterns in our couple outfits and family outfits (A. K. A. This dress is a combination of more than three colors and almost suit all the body type of African Women. African wedding ceremonies are beautiful, glamorous & colorful with a sweet display of rich vibrant colors of African print fabrics and styles. African dress, Ankara dress, couple dress, to match, vintage dress, hand made,women fashion, dashiki print, trending fashion, suits, jacket. From the intricate designs and technique to the gorgeous modern styles that can be sewn, this beautiful, bright fabrics can be used for any/ and or every occasion. African print shirts Africa men usually, abrasion shweshwe jackets, abbreviate or continuing sleeves, with apart applique pants. Your email address will not be published. A beautiful African dress with well-structured attention to detail and … All the African dresses you'll ever need, including long African print dresses, maxi African print dresses, short African print dresses, modern African style dresses etc. 8:17:00 am African Fashion styles, types of fashion styles. We have put together the most classical and elegant African Ankara and aso ebi dresses . Nov 24, 2019 - Today we have decided to give you the best among the rest from our latest collection of Ankara styles.just scroll down here and check for our Top 25 Creative And Stylish Ankara Styles 2020 For Wedding African Shirt Dress / Midi African Dress / Shirt Dress Ankara / Pink Dress / Ankara Dress / African Prin… Here are pictures of African wear for wedding ceremonies. The dress you can see in the image below is one of the best African Print Dress Styles For Weddings. When we talk about the African Print Dress Styles For Weddings 2020 then it does not mean it all that white dress is permanently rejected by the African Women. You can have a look over this dress down in the picture. You can take ideas from these dresses or can choose any of these. African American Dashiki Maxi Dress Designs 2021, Latest Kitenge Dress Designs 2021 For Ladies Images, Ankara Short Jumpsuit Styles 2020 Pictures, African American Flower Girl Wedding Hairstyles 2021, African American Straight Hairstyles 2020 With Bangs, Keke Palmer Net Worth, Family Mom, Dad, Age, Date of Birth. 7 – Bride in a Soft Pink Gown. From shop VintageVeraTreasures. They come in different designs, sizes and fabrics. The surprising and amazing thing about Ankara fabric is that it can be cut into any style you can ever imagine of. African Women are very punctual about their tradition and culture so that is why no matter what they wear it follows their all rituals and traditions. Ankara fashion is inarguably one of the most trendy pieces of clothing promoting the African heritage. African American Plaited Hairstyles 2020 will also look good with these dresses. Anyone who has done a simple search of African clothes on Google will surely come across D’Iyanu.This ankara skirt is unlike most African print clothes made with cotton. Get the best looks of african fashion styles; such as latest ankara styles, modern african designs, casual work outfits, wedding guest outfits, aso ebi styles, lace aso ebi styles, ankara tops, skirt and blouse, kimono, new trends, african fabric, african clothing, african lace styles, mordern and beautiful ankara styles, latest ankara styles for ladies exclusively only on ankarahub.com Most of the Brides in Africa go for the colorful wedding dress rather than the simple one. Brides on this day seem to be keener than other guests and bridesmaid because every eye on this whole day is just on the bride and every one is in talking about what he wore, does it suits her personality or not, Does she wear it in right way, the matching accessories are looking fabulous or not. Every single African dress with trim will consistently stand apart regardless of the shading they are in. Choose one of the 2 styles. Since Africa is such a large and diverse continent, … Get the best looks of african fashion styles; such as latest ankara styles, modern african designs, casual work outfits, wedding guest outfits, aso ebi styles, lace aso ebi styles, ankara tops, skirt and blouse, kimono, new trends, african fabric, african clothing, african lace styles, mordern and beautiful ankara styles, latest ankara styles for ladies exclusively only on ankarahub.com There are many colors in the African Print Dress Styles For Weddings but the most favorite of ladies are like Orange, Blu, Purple, Mustard etc. below are the collection … SUBSCRIBE TO OD9JASTYLES. It’s … The most color that is famous and is in the latest fashion trend of the African Women are, Orange, Blue, Mustard, Purple and often white too and sometimes African Bridal goes with the multi-color dresses which are a mixture of more than 2 or 3 colors. #tabjasposa_lk #NWchoosefav #Nigerianawedding” Nigerians always love embracing unique and stunning Ankara styles and designs. African print skirt styles, African pencil skirts printed midi skirts, African maxi skirts are currently trending. Cute African Print Styles For The Wedding Guest. It’s time for the most favorite makeup tips. The collar designs vary to fully leverage the style diversity in this type of an African print dress. From shop TeeTeecollections. Nov 28, 2018 - 7,813 Likes, 310 Comments - No.1 Nigerian Wedding Blog (@nigerianwedding) on Instagram: “Left, middle or right? Well in these days these dresses are more preferred by the African Women for their wedding. Wedding Decorations Wedding Gifts Wedding Accessories Wedding Clothing Wedding Jewellery ... Vintage Deadstock 1980’s crop top bright African print style with padded shoulders VintageVeraTreasures. If you want to look for classy dressing, take yourself (not gatecrash) to an African wedding. These days in the fashion ramp none of the designers want to leave ramp without showing its African Print styles. African American Dashiki Maxi Dress Designs 2021, Latest Kitenge Dress Designs 2021 For Ladies Images, Ankara Short Jumpsuit Styles 2020 Pictures, African American Flower Girl Wedding Hairstyles 2021, African American Straight Hairstyles 2020 With Bangs, Keke Palmer Net Worth, Family Mom, Dad, Age, Date of Birth. Your email address will not be published. All original, distinctive styles for hours of elfish and pretty fun. you will surely love this collection of selected Elegant African Dresses for … Each dashiki is designed for a beautifully eye-catching experience! leopard print, zebra print and giraffe print tiers on this safari themed wedding cake. Mostly the style on African wedding used is the A-line with the floor length bottom but other than that the bridal also uses mermaid style, Frock, Skirt and other that are according to their own dreamy dress. 0. 20 Pictures: Wedding Styles For African Woman – Aso ebi Styles 2021. In Ghana, there’s a traditional wedding and a church wedding … In the white wedding dress, most Africans go with the small patterns and yes Motifs too as you can see the pictures below. This is the reason that Bride on that day want everything should be so perfect that no one can have the word to express that how pretty she is looking. This African Print Dresses For Weddings is a combination of the Arab and European countries but the print of the bridal dress is purely of the African. This dress is always in the mermaid style and one of the best things about this dress is that colorful African Print. Check out this YouTube video on African wedding styles African Print Skirt and blouse Outfits - Fashion and Styles for Wedding . One thing which matters a lot is that no matter what you wear on your wedding but that should suit your personality because this day is a special day in your whole life so everything should be so perfect that your day will be a good memory for you in your whole life. These days, Africans rock the local prints for wedding ceremonies. The attraction in your African Print Dress Styles For Weddings 2020 is in the sewing pattern that in which style you made your dress. Kureas african pattern print maxi dress with side slits v neck hlaf sleeves long dress. Jun 17, 2019 - Explore Nale Lawson's board "african wedding guest outfit" on Pinterest. Here is a great idea of a look for a wedding guest, we have selected some lovely great collection of African Print Dresses for Wedding Guest that will make stand out among other guest at any wedding you plan to attend this season.. These days, women’s native wear don’t have to come in matching tops and trousers only, we have only tops or shirts that are printed in African or Ghanaian colors or even lace material that can be comfortably worn on a pair of women’s jeans that combination you will like because it is unique and stylish. This combination are now could be seen is celebrities too on their wedding day so that is why this fashion is getting popularity day by day. Aso-Ebi Dresses Styles 2020 For African Ladies are now possible if you look for something unusual. African print shirts for black boy – shweshwe . Get latest Ankara styles and attire trending now which you can even use for Asoebi. African Print Dresses and New Ankara Styles Trending in 2018. If it bags, necklace, shoes, snickers, spectacles, beads, scarfs, bangles or any kind of accessories, you’re sure to find them beautifully made with African prints. The look can be complemented by good high heel shoes, well done makeup, jewelry, and a … CLICK HERE TO SUBSCRIBE TO OUR YOUTUBE CHANNEL CLICK HERE TO SUBSCRIBE TO OUR YOUTUBE CHANNEL Welcome To 2021! Lily Kente Dress by Afro Throne. Although getting a … See more ideas about african dress african attire and african print fashion. We have rounded up 2021 African Fashion and Trending Ankara Styles Causing A Stare Right Now. African Print Skirt and blouse Outfits - Fashion and Styles for Wedding African Fashion Ville. African Lace fabrics have a method for making any African print wear more lovely. Due to this colorful African Print dresses it ad little essence to your personality too. Colors vary throughout the entire spectrum, but some of the most loved are: white, blue, orange, mustard, peach and purple. You’d be wrong if you thought kente print couldn’t he this pretty. These A-line dresses are one of the most favorite dress among all in the African Brides. African print dresses for wedding earned money domestically to stay individuals in jobs and food on tables. Today we bring you the fabulous Asoebi Wedding Styles Collection line. This color is most favorite because the texture and the mixing of this color make the dress more attractive as you can also see in the pictures below. Are you going to marry soon and curious about what to wear on your wedding because wedding is the one of the best place to show off your fashion sense. Post a Comment. With their guaranteed and brave styles, they never prematurely end to appearance us that – “More is completely included and underneath is a drag. Jul 12, 2019 - Hello ladies ! Od9jastyles.com-December 23, 2020. 51. African White wedding dress still is in the fashion trend. I have great admiration for African fashion dresses and have put together pictures of beautiful African dresses….from African print tops, Ankara styles to kente wedding styles. Round neck, v neck, sleeved and laced are the popular designs today. With amazingly rich colors, African wedding dresses really capture the essence of the big day. … These lovely styles are made up of African fabric that really make sense. is weekend again and we got you some lovely ankara styles that will give you that look for the next occassion.just scroll down and check them Are you looking for the Modern African Print Dresses Styles 2020 then here on this page the latest and up to the fashion trend dresses are shared with the pictures and other sewing styles.African Prints are more famous than any other fabric style all over the world. This Beautiful Collage of Modern African Print Styles For The Woman Of Colour and Power Ready To Dominate 2021, features […] The kente styles, ankara styles, African print jumpsuits, even a well designed kaba and slit.. Your email address will not be published. Maybe for various reasons, but I know for sure that we ladies love it because we get to show up in our glamorous glory, showing off all the glitz and glam, from stunning makeup looks, to high fashion gele styles, gorgeous Asoebi styles … You can never get enough of African print skirt and top styles. The color used with the white dress is most of the Cream, Brown and golden. The attraction in your African Print Dress Styles For Weddings 2020 is in the sewing pattern that in which style you made your dress. Ankara styles Ankara material is mostly one hundred percent cotton with very attractive, colorful patterns that are made using a dyeing method called batik. The lace detail carries with a dash of the western culture which when intertwined with the African print winds up with an extraordinary creation. This dress is a beautiful combination of more than two colors and the African Print Dress Styles For Weddings 2020 in A-line shape, In this A Line dress the upper part of the dress is your body fit but from the bottom its wide as we write English Word A so that is why this style is known as A Line dress. The beauty of the White African Print Bridal Dress is not can be compared with any other dress. If you’re going … finished with exotic looking green roses. This Beautiful Collage of Modern African Print Styles For The Woman Of Colour and Power Ready To Dominate 2021, features […] Colors vary throughout the entire spectrum, but some of the most loved are: blue, orange, mustard, emerald and purple. The head is also covered with a golden cloth with a little jewelry. May 10, 2019 - Sha Sha New designs drops her latest collection of Traditional Wedding Outfits for African couples. Set your style statement with such classy designs. These lovely styles are made up of African fabric that really make sense.

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Osteoarthritis (OA) is the most frequently diagnosed joint degenerative disease and the biggest growing chronic disease in the Netherlands. It is anticipated that the OA patient population will double towards 2.2 million patients in 2040 in the Netherlands alone, and towards hundreds of millions worldwide. The number of years during which patients experience pain and disability due to OA is rapidly increasing and one of the underlying causes can be found in the global increase of life expectancy. Despite the growing OA epidemic and major socio-economic impact, the population is facing a staggering lack of disease-modifying therapies that can preserve joint function by preventing cartilage- and joint degeneration and delaying OA progression. This leaves invasive total joint replacement as the only currently available option to treat the consequences of end-stage OA. However, considering the increase in life expectancy, a demanding active life-style and an unexplained growing number of young OA patients, costly and high-risk revision surgery of the primary prosthesis is a growing major problem that we should be solving by delaying the need for total joint replacement by innovations from basic research. The OSTASKILLS project is based on a research programme comprising four major pillars, providing the doctoral candidates training in the clinical development and market introduction of medical devices, pharmaceutical products and advanced therapy medicinal products in the area of joint repair. They are overarching and cross-fertilizing major domains and levels of life science and will feed entrepreneurial training of scientists to translate key basic science findings towards meaningful clinically applicable interventions. These 4 pillars, topic-wise, cover currently promising key approaches to support the preservation of joint function, repair of cartilage defects and prevent OA
Pillar 1 | Medical devices
Lead | Marcel Karperien – Twente University
Other partners | Pieter Emans – Maastricht University
Background Cartilage defects caused by trauma or ageing are an important risk factor for disturbance of joint homeostasis and development of OA.
Translational innovations To address this risk factor and postpone OA development, Twente University has developed a polymeric formulation capable of long-term intra-articular filling cartilage defects of different sizes and shapes, inducing regeneration of the damaged cartilage. Excellent pre-clinical results have been achieved in equine models and the technology is now ready for clinical introduction. Maastricht University is developing a non-degradable polymeric composite (sub-)chondral plug with cartilage-like biophysical properties, to repair focal (osteo)cartilage defects for middle-aged (35-65 yrs.) patients who, due to their calendar age or joint age, are not capable to regenerate their cartilage.
Patient’s opportunities These two medical devices are now ready for clinical implementation and subsequent market introduction. The doctoral candidates will contribute to the development of the required ISO certified quality management systems, the design, implementation and execution of the clinical trial and the development of a medical device dossier suited for submission to the notified body.
Needed to bring innovation forward in 5 years to come Successful clinical and market innovation in medical devices for cartilage repair field depends on the acquisition of a CE mark provided by the notified body. The doctoral candidates will have the opportunity to explore all aspects of building a medical device dossier needed for obtaining such approval.
Benefits for the doctoral candidates Successful innovations in the field of cartilage repair depends on the easiness of the surgical procedure and handling of the medical device, the potential for surgical introduction in a minimally invasive manner, its success in cartilage regeneration and/or replacement and thereby restoring joint homeostasis for low costs. The above described technologies meet these criteria. Both products target specific patient populations and have largely completed preclinical testing. They are now ready for clinical introduction and seek to obtain a CE mark for market introduction. Given the infancy of the trajectory ultimately leading to market introduction in 5 years, at earliest timepoint, from now, provides ample opportunity for the doctoral candidates to experience and familiarize with all aspects needed for building a medical device dossier. We offer training in a basic research laboratory, an academic medical centre as well as in the participating SMEs which intend to bring the technology to the market. This provides a unique opportunity to approach the goal from different perspectives. With the recent introduction of the medical device regulations (MDR) in the EU much uncertainty exists in the approaches that should result in obtaining a CE mark for a medical device. The doctoral candidates will get hands on experience with this new regulation which will make them ideally suited for positioning themselves for a career in a company that plans to certify new medical devices after completion of their training.
Pillar 2 | Pharmacological compounds – peptide-based drugs
Lead | Tim Welting – Maastricht University
Other partners | Marcel Karperien – Twente University, other partners | Wurzburg University
Background Pharmacologically treating (early) OA or conditioning the joint homeostasis after cartilage trauma shall become an important avenue to attenuate the progression of OA-related cartilage-/joint destruction, or prevent initiation of cartilage pathology following cartilage damage, respectively.
Translational innovations Several key growth factors and druggable pathways have been identified in the past decades that are capable of regenerating cartilage and attenuating OA development. However, drug-based treatment of cartilage pathologies comes with critical challenges that are quite unique for the joint: the synovial space is a harsh environment for biologics and treatment of a single joint with biological agents must be applied locally (intra-articular). Due these challenges the targeting of key druggable pathways for cartilage regeneration and OA treatment with biological agents is hampered. Local intra-articular treatment using growth factors is largely incompatible with the synovial space due to their molecular instability. To overcome this important limitation, Maastricht University has a fundamental research program on the discovery and mechanism-of-action of bioactive peptides from key growth factors (such as BMP-7) for cartilage regeneration and OA treatment, to mitigate cell biological processes like cartilage hypertrophy and cartilage formation. Based on this research selected lead peptide compounds are being developed for future clinical application and investigating pharmacokinetics, pharmacodynamics and safety of lead peptide compounds for intra-articular application.
Another clinically promising route to alter joint pathological molecular processes, while circumventing the challenging nature of the joint, is the use of VHHs (variable domain of heavy chain only antibodies). The University of Twente has developed VHHs that can induce tissue regeneration and/or reduce pain. VHHs have various advantages over conventional antibodies. They are small and extremely stable, consist of a single peptide chain and are equally effective in antigen binding and/or neutralization in comparison to conventional antibodies. VHHs are amenable for facile genetic modification optimizing antibody properties and due to their small size, they can be cost effectively produced using bio fermentation processes in yeast for a fraction of the costs of conventional antibodies. Particularly relevant for cartilage repair VHHs can easily penetrate the dense cartilage matrix in contrast to the impaired capacity of conventional antibodies to reach the cartilage embedded chondrocytes. VHHs thus have great potential to translate into an antibody based intra-articular injection therapy to mitigate processes like pain by blocking the NGF/TrkA pathway, inflammation by neutralizing inflammatory cytokines and or activation of cartilage formation by targeting growth factors and/or chondrocytes.
University Hospital of Regensburg (UHREG) has great expertise with patient-derived chondrocytes as well as with and 3D in vitro hypertrophy model for chondrogenically differentiating human Mesenchymal Stem Cells (MSCs). Moreover, human chondrocytes can be isolated (under approved and running ethical grants at UHREG) from cartilage trauma patients as well as early and late state OA patients and thereafter, cultivated in vitro. In collaboration with Maastricht and Twente Universities the effects of bioactive peptides and VHHs will be evaluated on the clinically relevant cell types available in UHREG. Furthermore, the bio-active peptides will be implemented in the in vitro hypertrophy model and evaluated for their ameliorating potential of MSC conversion to hypertrophic chondrocytes.
Patient’s opportunities Peptides and VHHs are novel biologic agents that can potentially be used for the treatment of cartilage pathologies to influence the homeostasis of the joint and or reduce joint pain/inflammation, thereby preventing/modifying OA and reducing OA clinical symptoms.
Needed to bring innovation forward in 5 years to come Successful clinical implementation of above-mentioned biopharmaceutical compounds depends on many success factors. One of them is patient stratification. To obtain more insight into disease heterogeneity on an individual patient level, the doctoral candidate will contribute to implementing cell biological assays for stratifying responder and non-responder cartilage defect- and OA patients. The doctoral candidate will contribute to investigating pharmacokinetics and pharmacodynamics of novel intra-articular drug compounds and will be involved in further developing peptide and VHH technology to be able to clinically validate the technology. This involves steps including the humanization of the VHH technology; peptide/VHH GMP production/purification and GLP tox, and relevant animal experiments including clinical trials in animal patients before proceeding to clinical trials.
Benefits for the doctoral candidates Pharmacologically treating intra-articular pathologies, like cartilage defects and OA, requires out-of-the-box non-classical pharmacological approaches, to acquire enough local compound concentrations and to reach target cells effectively/selectively. In addition, it is becoming increasingly evident that cartilage defect- and OA patients are a heterogeneous group of patients, with subpopulations that ideally need to be stratified for responsiveness-to-therapy. Furthermore, doctoral candidates will learn isolation, cultivation and investigation of clinically relevant patient-derived chondrocytes. In addition, fundamental knowledge on disease stage related chondrocyte phenotypes will be gained. The candidate work will contribute to understanding the patient response to the pharmacological cues as well as optimize the effectiveness of anti-hypertrophy agents. This will improve the potential outcome of clinical trials and, upon clinical implementation, will improve the cost effectiveness of these treatments. Given these basic prerequisites and challenges for future intra-articular treatment strategies, the doctoral candidate will benefit from a multidisciplinary environment in which ample opportunities for training in design of bioassays/compound screening, patient stratification, biotechnology, pharmacokinetics, pharmacodynamics and regulatory requirements for drug development.
Pillar 3 | Cell therapy
Lead | Ivan Martin & Andrea Barbero – University of Basel
Other partners | Twente University – Wurzburg University – Lund University
Background In the past decade it has become clear that cell therapy for preserving joint homeostasis can be highly effective and the paracrine actions of diverse preparations of mesenchymal stems have been demonstrated to attenuate the development of OA. Similar properties have recently ascribed in neuroectodermal derived nasal chondrocytes. Standardization of cell preparations and effective local delivery and retainment/survival of the therapeutic cells poses a hampering issue in this field that must be addressed to safeguard this promising development for patient use soon.
Translational innovations University of Basel has demonstrated that cartilage tissues engineered by adult nasal chondrocytes maintain their cartilaginous properties after being exposed in vitro to a variety of inflammatory factors. Experiments performed in microfluidic devices showed that the secretome of nasal chondrocytes positively influences the inflammatory profile of OA cells. In in vivo models, tissue generated by nasal chondrocytes efficiently integrates into the adjacent native OA tissues, along with survival of the implanted cells. Such properties were observed even once nasal chondrocytes were immediately implanted in vivo after their isolation from the cartilage biopsy. In collaboration with UHREG, crosstalk between the nasal chondrocytes and cartilage trauma and OA chondrocytes will be investigated in vitro to outline paracrine cellular communication and expected benefits of the therapeutic strategy.
Patient’s opportunities nasal chondrocytes isolated using a rapid isolation protocol can be encapsulated in gel and thus used for a single-stage cartilage repair approach.
Needed to bring innovation forward in 5 years to come A phase I clinical trial would be mandatory to assess the safety and feasibility of intraoperative injection of nasal chondrocytes for the treatment of cartilage lesions.
Benefits for the doctoral candidates This pillar will support the training of doctoral candidates on in vitro and ex vivo studies, using chondrocytes, the use of specifically designed bioreactors allowing control over the tissue environment and the use of microfluidics systems platform allowing to investigate in a high-throughput manner cells/tissue responses to bioactive factors. The recruited doctoral candidates will have a unique opportunity to acquire complementary expertise (cell biology, biomaterials science and bioengineering) and to be in contact with different backgrounds and actors of the regenerative medicine field. The doctoral candidates will have the possibility to acquire considerable networking opportunities for their future career. Moreover, the doctoral candidates will have the possibility to get several high-quality peer-reviewed publications that will contribute to increase the quality of their CV.
Pillar 4 | Tissue-engineering
Lead | Martin Stoddart – AO Research Institute Davos
Other partners | Maastricht University – Wurzburg University - Lund University
Background Tissue engineering of cartilage is one of the earliest fields of regenerative medicine that started developing decades ago, and only now we start to understand all critical aspects of the combination of cellular biology, biomaterials and molecular signals, to properly engineer cartilaginous constructs for implantation. Although tissue-engineering approaches for cartilage repair and osteoarthritis have been developed over the past decades, the implementation of these therapies in clinical practice and standard of care has been slow and often limited. True cartilage regeneration rather than the formation of fibro-cartilage tissue remains unsolved and there is still an important need to further improve our understanding and develop improved Tissue engineering approaches. To do so there is a need to improve 1) the cell delivery, survival and action through enhanced biomaterials, 2) define the mechanism of action of the implanted cells (e.g. chondrocytes, stem cells) and control their fate (e.g. avoid hypertrophy), 3) develop more relevant in vitro models for screen of tissue engineering solutions.
Translational innovations Maastricht University is developing an autologous in situ manner to generate subperiosteal cartilage from residing stem cells for treating focal cartilage defects. The AO Research Institute Davos is developing autologous mesenchymal stromal cells tissue engineered solutions. A numerical model is being developed to design 3D printed biomaterial scaffolds for optimal mechanotransduction of embedded stem cells for their differentiation toward a chondrogenic phenotype in absence of growth factors and under mechanical load mimicking knee joint kinematic. A multiaxial mechanical load bioreactor is developed and used to assess effect of mechanical load patterns and optimize tissue-engineering solutions. In order to gain insights into the integration process of engineered cartilage constructs to the surrounding cartilage tissues, UHREG will investigate in collaboration with AO institute the response of clinically relevant cartilage trauma and OA derived chondrocytes to the cartilage analogs engineered in this pillar. Moreover, the biomaterials designed in this pillar will be evaluated in the UHREG established 3D in vitro hypertrophy model with chondrogenic human MSCs.
Patient’s opportunities The understanding gained in studying the effect of compression and shear loads on the chondrogenic differentiation of different sources of stem cells can now be potentially translated by designing better post-operative physiotherapy for improved stimulation and recovery of patients.
Needed to bring innovation forward in 5 years to come Numerical model applied to the design of 3D printed scaffolds for cartilage tissue engineering allowing for more robust response of cells therapy under optimized physiotherapy protocols.
Benefits for the doctoral candidates We aim to make significant advance towards the introduction of regenerative therapies for cartilage repair and treatment of osteoarthritis (OA) into the clinic. Therefore, doctoral candidates that can develop new therapies while keeping clinical and regulatory conditions in mind are needed for developing new solutions and their future exploitation. By offering a comprehensive training program that encompasses an extensive range of interdisciplinary skills and addresses the recognized gap in knowledge and clinical translation, we will train a new generation of scientists that can be the mediator between fundamental and basic science on one hand and clinical uptake and application on the other hand.


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Equal Rights was a publication of the National Woman's Party. Began in 1923, it was the successor to the failed Suffragist. Its name is representative of its purpose: the editors of the newsletter believed that the only way to achieve equality amongst the sexes was to introduce an Equal Rights Amendment to the Constitution. In addition to lobbying for the introduction of a Constitutional Amendment, it discussed feminist concerns, and developments on a national as well as a global scale. In 1935 the editor of Equal Rights left the Party to create the independently published Equal Rights: Independent Feminist Weekly. The NWP still maintained the publication of the newsletter(as well as the name Equal Rights), but with a new editorial staff. The Valdosta State University Archives houses copies of the NWP's Equal Rights from 1924-1954, as well as a few editions of the Independent Feminist Weekly.
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Former Columbus Zoo Director Emeritus Jack Hanna has been diagnosed with dementia. The popular wildlife advocate's three daughters announced the news in a lengthy statement shared to Twitter on Wednesday. "Today we reach out to share some personal Hanna Family news.
Doctors have diagnosed our dad, Jack Hanna, with dementia, now believed to be Alzheimer's disease. His condition has progressed much faster in the last few months than any of us could have anticipated.Read more on foxnews.com

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The Dragons return to our screens on Sunday evening putting fear into entrepreneurs who are looking for that all important vital cash injection.
Duncan Bannatyne, Peter Jones and Deborah Meaden are joined by Piers Linney and Kelly Hoppen on the second half of series 11. The Dragons will be treated to pitches from entrepreneurs looking for investment in exchange for equity.
Tonight’s show features two graduates from Manchester who are looking for investment in their youth-orientated package holiday business. A Bulgarian inventor makes a splash when he asks for £1 million investment for his self-filling bath.
Dragons’ Den airs tonight at 9.00pm on BBC Two.


Handyman Matthew restores benches for free
MACCLESFIELD Town Council looked local to help restore two benches.
They turned to handyman Matthew Sanders, 37, to refurbish the seating at the junction of Churchill Way and Chestergate. But when Matthew, who runs Macclesfield Domestic Services, heard one of the benches was a memorial to Carl David Neild, he offered to fix it for free.
Pete Turner, clerk of Macclesfield Town Council said: “We have a lot of benches and street furniture in the town and for a while I have been trying to establish a scheme of repair, replacement and maintenance.
“I contacted a few companies to get quotes and Matthew was so proactive and helpful. He refused to charge for the memorial bench, which I think shows a high degree of integrity.
“The end result is excellent and I’m already talking to Matthew about some more repairs in the town.”
Matthew, a single dad who lives on Moss Lane, set up the business earlier this year after losing his job.
He said: “It was really nice to hear from passers by how much they appreciated that the town council was repairing the benches and that they valued my work.”


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- Download 100094
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Bricks Breaker - Glow Balls
Bricks Breaker Glow Balls is an android game which is of very less size. The game looks very simple but it is one of the most interesting game. In this android game, you need to break the bricks with full focus. If you lose your concentration and focus at the same time you will lose the game. So, this game is good for brain relaxing and to increase the brainpower.
The game is full of fun and excitement. If you got bored of playing all shooting and hooting games and want a game that gives pleasure to your mind then this is the best option for you.
- Colorful glow skins.
- Free to play.
- Easy game controls with one finger.
- More skins of ball!
- Thousands of stages! Endless game mode.
- More props to get more fun!
- Use 50 balls from the game start.
- Achievements & leaderboard supported.
- Play offline: Enjoy this game without WiF

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The Elder Scrolls IV Delayed
We won't be living in Oblivion until next year.
According to the announcement, which offers lowered guidance for fiscal 2005 and 2006, Oblivion has been moved from the company's first quarter, which ends in January, to its second quarter -- February through April 2006.
For Q1 2006, the company now expects to post $300 to $350 million in net sales -- numbers which reflect the delay of Bethesda's ambitious RPG sequel.
So far, neither Take-Two nor Bethesda have offered reasons for pushing back Oblivion, though given the game's scope, many expected the title may not reach stores in time for holiday shopping.
We'll be back as we learn more.


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novelty and surprises. They are big on emotions and
expression. Life is an exciting drama. They are good at
sales, advertising, politics, and acting.
5% of the total population.
ENFPs have a tendency to overextend themselves in both their physical and emotional commitments. Their proclivity to procrastinate and to overlook details complicates their circumstances. ENFPs often move on to new ventures without completing those they have already started. Their charming personalities can show signs of irritability and over-sensitivity when their desires to please different people come into conflict. During times of stress, ENFPs feel alienated. They then engage in deceptions that serve to obscure what is occurring within themselves.
The ENFP finds symbolic meanings behind the immediate circumstances. These meanings are construed as foreboding problems when ENFPs are under stress. Having a pervasive feeling of losing control over their own independent identities, ENFPs will feel virtually split apart by intruding circumstances. They will be "besides themselves" and "just not all there" — as if something, or someone, has taken away the essence of who they are. Not feeling like themselves, the ENFP will become subject to their own feelings of shame for being a phony, a fake or an impostor. If stress continues to grow, they may attribute malevolent schemes to others in order to explain away their fears.

domain: psychology


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Car bomb explosion kills Damascus mufti west of Syria’s capital
A prominent Syrian Muslim cleric has lost his life when a bomb blast targeted his car outside the capital Damascus.
The explosion that killed Damascus Mufti, Sheikh Mohammed Adnan Afyouni, took place in the city of Qudsaya, located 7 kilometers (4.3 miles) west of Damascus, on Thursday evening, Syria’s official news agency SANA reported.
The cleric was first reported wounded and then declared dead soon after.
It was not known who had planted the bomb, and no group immediately claimed responsibility.
Syrian Minister of Endowment and Religious Affairs, Mohammed Abdul-Sattar al-Sayed, denounced Afyouni’s death, calling it a terrorist act.
“No matter how hard they (terrorists) would try through firepower and abhorrence, they would not be able to silence the voice of love which Sheikh Adnan projected across Damascus, its countryside and Syria. They cannot stifle true Islam, as well as the voice of truth and moderation…,” he added.
Sayed highlighted that the war on Syria has not ended, and that his ministry and its scholars will do their utmost to shield all religious institutions and mosques from the invasion of extremism.
Sheikh Afyouni had apparently been a key figure in the Syrian government's reconciliation deals with foreign-sponsored militant groups on the capital's outskirts.
He was one of the mediators of the August 2016 deal under which militants in the city of Daraya, situated 8 kilometers (5 miles) southwest of Damascus, surrendered after a four-year bloody battle.


Most natural rubber comes from rubber trees in Southeast Asia, but this source is now under threat from a fungus. Researchers have optimized the Russian dandelion to make it suitable for large-scale rubber production.
Anyone who has picked dandelions as a child will be familiar with the white liquid that seeps out of the stalks as you break them off. Viscous, sticky - and a much sought-after material: natural latex.
Around 30,000 everyday products contain natural rubber, everything from car tires, catheter tubes, latex gloves to tops for drinks bottles. Car tires, for instance, would not be elastic enough without the incorporation of natural rubber. The bulk of this material comes from rubber trees in Southeast Asia. Rubber produced in this way can, however, cause allergic reactions, which is clearly an issue with clinical products.
A fungus is also creating concern for rubber cultivators. In South America the infection is now so widespread that large-scale cultivation has become virtually impossible. The disease now also appears to have taken root in Southeast Asia's rubber belt. Fungicides still provide at least temporary protection. But if the fungus disease was to reach epidemic proportions, chemical crop protection would be rendered useless - experts fear that the natural latex industry could collapse if that were to happen.
Researchers are therefore turning to other sources - such as the Russian dandelion. Germans, Russians and Americans produced rubber from this plant during the Second World War. Once it is cut, latex seeps out, albeit difficult to use as it polymerizes immediately.
Scientists from the Fraunhofer Institute for Molecular Biology and Applied Ecology IME in Aachen have now come a step nearer to large-scale rubber production from dandelions. "We have identified the enzyme responsible for the rapid polymerization and have switched it off," says Prof. Dr. Dirk Prüfer, Head of Department at the IME. "If the plant is cut, the latex flows out instead of being polymerized. We obtain four to five times the amount we would normally. If the plants were to be cultivated on a large scale, every hectare would produce 500 to 1000 kilograms of latex per growing season." The dandelion rubber has not caused any allergies so far, making it ideal for use in hospitals.
In the lab the researchers have genetically modified the dandelion. Their next step will involve cultivating the optimized plants using conventional breeding techniques. In around five years, Prüfer estimates, they may well have achieved their goal. In any case, the dandelion is not just suitable for rubber production: the plant also produces substantial quantities of inulin, a natural sweetener.


text:
We've always loved vibe of the Loring Pasta Bar, from the starry atmosphere and the surprisingly neat bathrooms, to the exposed brick, plush couches and candles burning. It's not just your average bar, but a delicate slice at perfectionism; all to take you away from the seedy, disheveled conditio ... More >>
Local songs spun on today's Mischke broadcast.
On today's show, Mischke played four different tracks by Northfield singer Meredith Fierke.
Stream new Bob Mould, Dan Auerbach played the Current, Tapes 'n Tapes in DC & reactions to Brother Ali's new EP
An update on Brother Ali's new single, Gospel Gossip and Meredith Fierke reviewed & Anya Marina performs at the Current
Simmering siren refuses to be just another girl with a guitar
Jason McLean's email (from "Varsity Theater Reopens"): We are In Business!!! Today, Friday, April 15th, the City of Minneapolis, in it's infinite wisdom, granted a Certificate of Occupancy to the Varsity Theater Project. Shows will soon resume. The first show will actually be tonight, Conversat ... More >>

domain: artistic


Bruce MacKinnon, editorial cartoonist for The Chronicle-Herald, drew a cartoon in response to last month’s the shooting in Ottawa’s Parliament building. The cartoon has resonated with many. Global News has a video interview with Bruce about drawing that cartoon.
MacKinnon said the response has been overwhelming.
?I think it also speaks to the emotion attached to this story and the powerful symbolism,? he said. ?It?s a lot of forces that combined to get that kind of response. It?s very touching.?


North East, Nissan to explore e-car promo plan
Agree to talk about holding talks
'Leccy Tech Regional development agency One North East (ONE) continues to try to make the north east of England the centre of 'leccy car stuff in the UK.
ONE and Nissan have agreed to explore the development of a zero-emission mobility programme in the UK. The signing took place in the presence of Business Secretary Lord Mandelson, who was visiting the region to promote all things EV.
Under the terms of the agreement, Nissan and ONE will examine the feasibility of promoting EV use in the UK and North East and of developing an EV infrastructure in the area. They'll also “explore the potential to manufacture EVs in the UK/North East and provide incentives for EV development”.
That last bit is one of the keys to securing the long-term future of Nissan as a manufacturing concern in the UK.
White Van Mandy
According to ONE, “although no commitment beyond the feasibility study has been made at this stage, the memorandum of understanding represents an important step in the potential launch of electric vehicles in the UK in the near future.”
So while nothing is guaranteed, it's still better than a slap in the chops with a bloater.
Renault-Nissan currently has similar or more advanced agreements in place with a number of countries including Israel, Denmark – both in partnership with Shai Agassi's Project Better Place organisation – Monaco and Portugal, along with a handful of cities and states in both the US and Japan.
While at Sunderland, Lord Mandelson went a step further by suggesting to Nissan it should make its e-car batteries in the UK too.
Not a bad idea, but don't forget, m'lud, that Nissan recently agreed a $1.1bn (£692m) deal with NEC to make its EV batteries in Japan.
After his visit to Nissan, Mandy dropped in to say hello to the folks at Smith Electric Vehicles where he congratulated the company “on their partnership with Ford which will export British low-carbon technology to the United States and secure British jobs in Sunderland". ®


text:
The Iowa Department of Natural Resources continues a series of public meetings to discuss water quality plans for lakes and rivers. The D-N-R’s Danelle Haake says they’ve put together draft plans for the lakes or river called “Total Maximum Daily Loads” or T-M-D-L’s.She says all the waterbodies have been listed on the state’s impaired waters list. She says the T-M-D-L is written to determine what the maximum amount of a pollutant is that can reach the waterbody and still have it meet state water quality standards. Haake says the public meetings let people discuss the T-M-D-L and plans for cleaning up the water. She says “getting from this is what’s wrong with the lake to this is how to fix it is kind of what these documents do.” She says they want the public’s input to see if they have other information that’s different from what the planners have thought. Haake says the D-N-R does what it can to identify problems, but local people often have information that’s been missed. She says there’s some cases where they think there’s a problem from a certain type of source, but the local people may have information that that’s not the problem and maybe it’s something else. Haake says local people can also help confirm problems. She says an example is some waterways that have sediment, and they think it’s related to sediment from gully erosion. She says local people can confirm that there are gullies in the area. The are two meetings tonight for Clear Lake at the Lakeview Community Room at the City Park in Clear Lake at six o’clock. And for Milford Creek at the Iowa Great Lakes Maritime Museum in Arnolds Park at 6:30 p-m. Tomorrow there’s a meeting for Pierce Creek Lake at one p-m at the Page County Courthouse in Clarinda. And for Lake Macbride at the Solon Library at 5:30. For more information, check out the D-N-R’s website at:www.iowadnr.com.
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text:
During embryogenesis, the neural stem cells (NSC) of the developing cerebral cortex are located in the ventricular zone (VZ) lining the cerebral ventricles. They exhibit apical and basal processes that contact the ventricular surface and the pial basement membrane, respectively. This unique architecture is important for VZ physical integrity and fate determination of NSC daughter cells. In addition, the shorter apical process is critical for interkinetic nuclear migration (INM), which enables VZ cell mitoses at the ventricular surface. Despite their importance, the mechanisms required for NSC adhesion to the ventricle are poorly understood. We have shown previously that one class of candidate adhesion molecules, laminins, are present in the ventricular region and that their integrin receptors are expressed by NSC. However, prior studies only demonstrate a role for their interaction in the attachment of the basal process to the overlying pial basement membrane. Here we use antibody-blocking and genetic experiments to reveal an additional and novel requirement for laminin/integrin interactions in apical process adhesion and NSC regulation. Transient abrogation of integrin binding and signalling using blocking antibodies to specifically target the ventricular region in utero results in abnormal INM and alterations in the orientation of NSC divisions. We found that these defects were also observed in laminin a2 deficient mice. More detailed analyses using a multidisciplinary approach to analyse stem cell behaviour by expression of fluorescent transgenes and multiphoton time-lapse imaging revealed that the transient embryonic disruption of laminin/integrin signalling at the VZ surface resulted in apical process detachment from the ventricular surface, dystrophic radial glia fibers, and substantial layering defects in the postnatal neocortex. Collectively, these data reveal novel roles for the laminin/integrin interaction in anchoring embryonic NSCs to the ventricular surface and maintaining the physical integrity of the neocortical niche, with even transient perturbations resulting in long-lasting cortical defects.
ASJC Scopus subject areas
- General Neuroscience
- General Biochemistry, Genetics and Molecular Biology
- General Immunology and Microbiology
- General Agricultural and Biological Sciences

domain: medical


Published: May. 27, 2022 at 2:02 PM EDT
ELIZABETHTOWN, N.C. (WECT) – The last girder was installed Thursday on the south end of the US 701 bridge over the Cape Fear River in Elizabethtown.
According to a post on social media by the Town of Elizabethtown, the North Carolina Department of Transport said the girders for the north side will be delivered in August.
At that time, the remaining work will be carried out from the north bank of the river.
Copyright 2022 WECT. All rights reserved.


text:
METHODS: We isolated a strain of C. albicans from plaques on the oral mucus membrane of an infected patient. Colonies of this strain were exposed for 1 24 h, to 5%ALA-PTt, 5%ALA-PTt buffered to pH 6.5 (the pH of the oral mucosa) (5%ALA-PTtb) or not exposed (control). The 1 h-exposed samples were also irradiated at a wavelength of 630 nm with 0.14 watts (W) and 0.37 W/cm2 for 7 min at a distance of <1 mm.
RESULTS AND CONCLUSION: The 5% ALA-PTt preparation was shown to be effective in reducing the growth of biofilm and inoculum of C. albicans. This effect seems to be linked to the intrinsic characteristics of 5%ALA-TPt, such acidic pH and the induction of free radical production. This outcome was significantly enhanced by the effect of PDT at relatively short incubation and irradiation times, which resulted in growth inhibition of both treated biofilm and inoculum by ∼80% and ∼95%, respectively.
Purpose: A Central Composite Rotatable Design (CCRD) of Response Surface Methodology (RSM) was used purposely to optimize process parameters conditions for formulating nanoemulsion containing aripiprazole using high emulsification methods.
Methods: This design is used to investigate the influences of four independent variables (overhead stirring time (A), shear rate (B), shear time (C), and the cycle of high-pressure homogenizer (D)) on the response variable namely, a droplet size (Y) of nanoemulsion containing aripiprazole.
Results: The optimum conditions suggested by the predicted model were: 120 min of overhead stirring time, 15 min of high shear homogenizer time, 4400 rpm of high shear homogenizer rate and 11 cycles of high-pressure homogenizer, giving a desirable droplet size of nanoemulsion containing aripiprazole of 64.52 nm for experimental value and 62.59 nm for predicted value. The analysis of variance (ANOVA) showed the quadratic polynomial fitted the experimental values with F-value (9.53), a low p-value (0.0003) and a non-significant lack of-fit. It proved that the models were adequate to predict the relevance response. The optimized formulation with a viscosity value of 3.72 mPa.s and pH value of 7.4 showed good osmolality value (297 mOsm/kg) and remained stable for three months in three different temperatures (4°C, 25°C, and 45°C).
Conclusion: This proven that response surface methodology is an efficient tool to produce desirable droplet size of nanoemulsion containing aripiprazole for parenteral delivery application.

domain: literature


NIRPC to consider new location; ‘open competition’ announced
By Carole Carlson email@example.com February 21, 2013 10:50AM
Updated: March 23, 2013 6:23AM
PORTAGE — The Northwestern Indiana Regional Planning Commission will accept proposals for a new location for its offices in the coming months.
It doesn’t necessarily signal a move from its current Portage location, just north of Interstate 94 at Indiana 249, but NIRPC’s lease is up at the end of the year.
NIRPC executive board member and LaPorte Mayor Blair Milo said at Thursday’s meeting that NIRPC was working with the Northwest Indiana Forum “to put together a fair and open competition” for proposals.
The two groups have been sharing space in Portage since NIRPC moved its offices from Highland in 1993. The move came after the Portage City Council issued a $1.1 million revenue bond to buy the land and construct the building and the newly created Portage Redevelopment Commission leased it to NIRPC.
The building does have some problems meeting the Americans with Disabilities Act requirements, said NIRPC attorney David Hollenbeck.
Hobart Mayor Brian Snedecor, who serves as NIRPC’s vice chairman, urged community leaders to submit proposals if they feel their municipality has a suitable location.
NIRPC is composed of members from Lake, Porter and LaPorte counties.
After the meeting, Milo said a committee planned to work as aggressively as possible to begin the bidding process.


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About San Jose
First, it was El Pueblo de San Jose de Guadalupe; then it was San Jose; then it was the Capital of Silicon Valley (okay, this one was for a 1988 publicity campaign). Whatever name it goes by, San Jose has a rich history, being one of California’s first cities as well as the state capital from 1849 to 1852.
With about 7,000 tech companies calling it home, San Jose is the most concentrated tech center in the world. It’s no wonder many famous inventions have come out of this sprawling city; Steve Wozniak, “The Wave” (you know that thing that crowds do at a sports game), the first computer hard drive, fruit cocktail.
Another San Jose oddity is The Winchester Mystery House. This 160 room house is an architectural phenomenon/nightmare that is a must see.
Speaking of other odd structures – San Jose has the world’s tallest rat statue of Chuck E Cheese (it’s almost 30 feet tall!) as well as a 930 square foot Monopoly game board that you can rent out to play, complete with a specially trained to “run a giant sized Monopoly game” referee.
San Jose has a lot to offer in history and attractions. We will leave you with one more (for all you classical fans): The Ira F. Brilliant Center for Beethoven Studies at San Jose State University owns a lock of Beethoven’s hair and the remains of his skull!
Things to See and Do


text:
Manchester United are close to signing Sporting Lisbon attacking midfielder midfielder Bruno Fernandes, Football Insider understands.
The 24-year-old is being chased by some of Europe’s elite clubs on the back of a remarkable campaign in which scored 32 goals and supplied 18 assists for his side in 53 matches.
A United source has told Football Insider that they are in pole position to seal the capture of Fernandes, who had an £88.5million release clause inserted into the contract he signed last summer.
The Premier League giants have not offered to pay the mammoth clause but have made it clear in negotiations with Sporting they are willing to pay more than £50million for him.
That could be enough to seal the deal and make him United’s first signing of what is expected to be a busy summer of recruitment following a wretched campaign.
Fernandes is in demand after taking his game to a new level this season at Sporting, who he helped win the Taca de Portugal as they beat Porto on penalties in the final last week.
The 11-times Portugal international was outstanding in all competitions, with 20 of his goals coming in the domestic league, putting him second only to Benfica star Haris Seferovic.
Fernandes also topped the league assists charts with 13, and his performances in the Europa League also alerted him to United’s recruitment team.
In other Man United news, it can be REVEALED that star club goalkeeper has agreed the terms of a long-term deal with a big pay hike.

domain: sports


text:
Jamie's Italian - Reading
Jamie's Italian Reading restaurant is based in a cracking building overlooking the river, slap bang in the heart of restaurant land! The centrepiece is the whopping bubble chandelier which,
especially at night, really sets the whole place off a treat. There are fantastic daily specials, as well as the great menu. Jamie's Italian now takes reservations of any size; Monday to Friday
lunch and 6 or more for evenings and weekends. Kids also eat free when dining with an adult having a main meal on Monday to Friday lunch times.
The Early Week Festive Menu £19.95.
Two-course dinner for £15.95
Two-course lunch for £11.95
The Festive Feast Menu £29.95
The Big Feast Menu £34.95
The Festive Lunch Menu £24.95

domain: food