Please note this event has been rescheduled to Monday 20 June 2022. The event was due to take place on Saturday 22 May 2021.YES, one of the most innovative of all prog-rock bands, and true legends of the genre, return to Liverpool Philharmonic Hall during The Album Series 2020 Tour, featuring their 1974 Relayer album in its entirety together with a selection of other classic YES favourites.
The show will comprise two sets by the band with full production and a high definition video wall. The first will feature favourite classic tracks from YES' extensive catalogue. The second will feature Relayer, the seventh studio album by YES, and one of the band’s most distinctive.
Released in late 1974, Relayer continued YES’ success reaching No. 4 in the UK album chart and No. 5 in the US Billboard chart.
Roger Dean will attend every show on the tour with an exhibition of his iconic art.
'We are really looking forward to playing ALL of the Relayer album...Having premiered The Gates Of Delirium this year, we continue by expanding our Album Series with all the tracks: The Gates Of Delirium, Sound Chaser and To Be Over...During the first half of the evening we'll be performing a refined selection from Yes' enormous 50 year + repertoire.'
8% administrative fee applies for online & telephone orders.
A £1 postage fee is applicable on all orders if opting for postal delivery.
More information about booking fees
Steve Howe: guitars, backing vocals (1970 –1981, 1990–1992, 1995–present)
Alan White: drums, percussion (1972 – present)
Geoff Downes: keyboards (1980–1981, 2011–present)
Billy Sherwood: guitar, backing vocals ((1994, 1997–2000), bass guitar, backing vocals (2015–present)
Jon Davison: lead vocals, acoustic guitar (2012–present)
Fri 27 May & Sat 25 June 2022 8pm Liverpool Philharmonic Hall


text:
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domain: food


text:
She was both nervous and full of anticipation.
After almost six decades of active participation in their samenleving she would finally retire into her well deserved rest of old age.
Let’s try again. This was what she was both nervous about and anticipating.
After almost six decades she would finally come into her phase of harvest.Of course, her body had already made that transition for her but now it would be confirmed and formalized samenleving-wise.
Remember the age groups of the advisory boards that support the leadership of The Three? These age groups were also known as the three phases of sowing, growing and harvesting. Rather pagan and rustic sounding right? There was however, sound science behind this choice of words. The field of Human Be-ing had established, by doing solid scientific work, that when a samenleving has Rites the Passages in place that are connected to the cycles of the natural world people tend to not cognitive dissonance themselves from the unavoidable reality of being part of those natural cycles and thus the natural world and tend to act accordingly in considering it obvious to work with those cycles.
Her name was Serah. She identified as a woman. Mostly. Sometimes she had liked to play around with the idea and practical execution of being fluid. But to be honest, she didn’t real care either way. Not anymore. Picking a gender identity and wrapping it around you like favourite coat was something for the youngsters. After a while one didn’t real care to name oneself anymore. What or who was a person anyway, besides an ever changing set of preferences, ideas, feelings, tendencies, skills and looks? But of course the sowing phase, in youngsters minds, was often attached to the idea that a set form would emerge at the end of it. But all that happened was that the continuity of change was becoming more subtle, for most anyway. Through the wild, seeking eyes of a youngster being above 30 looked like a static situation. But there was not a one who didn’t find out this was not the case. At all. Of course the Rite from Youngster to Middle did help in this respect. And that was the second scientific foundation of those Rites the Passage. They were designed to keep people from sticking to a phase that was behind them and being blind to the new possibilities that awaited them. Such a waste of human creatorship. Serah inwardly cringed a little bit when she recalled the story that she was sure to hear in the upcoming ceremony. About the times before the Great Redsign. The desperate attempts to appear young, the wasting away of old people in ‘care’ homes, the stuck-in-adolescence sexual desires from old people to young people, women in their transition to menopause being diagnosed with burn-out or depression due to the general ignorance about the various hormonal stages in female bodies. She was utterly grateful to not having had to to live in those dark ages.
Since her early 40s she had attended yearly meetings of her age group to be. These were designed to inform her of all the possible ways in which her body could start to express the change from fertility to the end of it. The physical aspects of it as well as the emotional and sexual aspects of it. The transition hadn’t been rough on her even though it hadn’t been easy either.
The dark but not yet dark blue of dusk was in the sky. Her favourite colour. She felt like her whole body breathed it in, while she walked towards the circle that had already gathered outside on the plain. People always come to their Rites alone. That was custom. And it was a good custom Serah decided. Even though she did remember the awkwardness of walking all by herself going to her first Rite as a child. It emphasised the inherent aloneness of a person. Her own core and boundaries. It was also good to be gathered up in the togetherness of the group. They had left a place open for her in the circle and she sat down, something fluttering in her belly.
“Serah, be welcome.”
She was glad to see who it was that had chosen to welcome her. Grey wisps of hair standing out and curling around a strong brown face with clear eyes. Anashali.
My friend, her heart said.
“Before you join us, let’s look back and say goodbye to where you are coming from.”
She let the words of the other woman of the middle group wash over her like a warm cleansing rain after a hot day.
Some of her accomplishments were mentioned as well as her struggles. Other people from her inner circle thanked her for various things she had done, said or inadvertently meant for them in the last 30 years. She felt tears prickle in her eyes and a warm glow in her heart.
Then the whole group stood up and split in two parts. She was taken with one half of the group to the bank of a little strong flowing brook a bit to the west of where they had sat. She could see the other half assembling on the other side of the bank. A big slab of smooth washed rock sat on both sides of the water.
Serah knew the drill. She had attended many of these rituals. Not much more words were needed now. She stepped onto the rock and faced the people on her site of brook. Silently she looked around at all the faces, many beloved, all well known to her. “Thank you” she said. And she closed her eyes and mouthed a silent thank you to .. what? The years past? Her body? Life itself?
To the wide wind that gently tangled her hair, the strong water at her back and the old rock under her bare feet.
These were the elements that were chosen for many Rites. wide wind, strong water, old stone. Elements of power and peace.
She turned around, sat down on the rock and let herself down into the shallow current. With careful steps so as not to slip she crossed the water and stepped up on the rock on the other side. Anashali stood on the bank. ‘Thank you” she said to Serah and the whole group behind her murmured the same thing. Thank you for joining our numbers, thank you for coming to add your flavour of life, your experience to this phase of our samenleving.
Serah nodded a gracious acceptance and stepped of the rock in the open arms of Anashali. She had arrived. A whole new phase awaited her.

domain: literature


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Amazon's aggressive push into entertainment
Three reports out Tuesday suggest that Amazon is pushing harder to corner the entertainment sector, with plans for a free TV streaming app, a live television recorder and a new slate of content deals with two of Hollywood's biggest movie studios.
Why it matters: One of Amazon's fastest-growing business units is advertising, which will continue to explode with investments in content and TV technology. Content investments will also help the streamer take on Netflix in a heated battle for digital streaming subscribers.
Three new investments:
- Amazon is planning an ad-supported Fire TV streaming app, nicknamed "Free Dive," that would rival that of Roku, The Information reports. Roku currently offers a free, ad-supported app for Roku devices called "Roku Channel." The Information reports that Amazon, like Roku, is in talks with major studios to license older TV shows to air on the app.
- It's also talking to Sony and Paramount for streaming rights to add more programing to its Amazon Prime video service, which is different from the planned "Free Dive" app, Bloomberg reports. (The app is for only for owners of Amazon's connected device, Fire TV.) Bloomberg reports Amazon is talking to Sony's studio division and Viacom's studio, Paramount Pictures.
- Amazon is also planning its own DVR service that would rival that of TiVo, Bloomberg reports. The device, nicknamed "Frank" within Amazon, is a new type of digital video recorder for the streaming era. The device would include physical storage and would connect to Amazon’s existing Fire TV boxes.
Some analysts predict that Amazon's ad business is growing so fast that it could reach $16 billion in just two years, surpassing its lucrative Amazon Web Services cloud business. But in order to do so, it needs to get advertisers to put their lucrative brand ads on Amazon — the ones they would typically put on TV.
Amazon has been pursuing content deals for years to help increase subscribers to its Amazon Prime video service, but has not been able to match the unprecedented scope of Netflix's content spend.
- Analysts think Amazon will spend upwards of $5 billion this year on original content, while others predict that Netflix could be spending up to $12 billion this year.
The bigger picture: Other aspects of Amazon's media business are also helping the Seattle-based company make more money, mostly from advertising, and drive customer engagement which could help fuel its commerce services.
- Twitch, which Amazon bought in 2014 for $970 million, is by far the most popular streaming platform for gamers, but is tiny compared to rival YouTube. It's looking to expand its user and creator base to sell more ads. Bloomberg reports that Twitch CEO Emmett Shear has a goal of $1 billion in ad sales, over double its current sales.
- Social media: Reports from last year suggest that Amazon is also investing in two different social media networks, one for shopping and one for messaging. Both networks could eventually present advertising opportunities, but would mainly be helpful in keeping users engaged on their platform while they use their other commerce and entertainment services, a similar strategy to that of Alibaba.
- Sports rights: As a part of Amazon's efforts to lure Pay-TV viewers, it has invested millions of dollars in sports rights, like its Thursday night deal with the NFL.
- Smart TVs: A report from the Telegraph earlier this summer suggest that Amazon is planning a smart television set, as well its own TV service.
Go Deeper: How Amazon is eating the media business
Editor's note: This post has been corrected to show that Netflix could spend $12 billion, not $12 million, on original content this year.

domain: economics


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Ninja Cat Description
Ninja Cat is a free online action game including two modes. Pick out the room you want and embark on the new journey in which you need to kill all of the enemies in the shortest time. Before going on, remember to keep an eye on the instruction that Ninja Cat provides. You will know how to perform abilities in the proper way. Not only that, you will master tips to deploy special effects and conquer dangerous obstacles on the path. Get ready to explore and become the winner now!
How To Play
Use WASD to move, WASD + Shift to slow down, WASD + Space to accelerate

domain: entertainment


text:
SPHENOID SINUSITIS Richard A. Hill, MD, Lenworth N. Johnson, MD, and Robert Parnes, MD Hershey, Pennsylvania
Significant morbidity and mortality can result if early detection and treatment of sphAenoid sinusitis is not provided. A case is presented in which the diagnosis of sphenoid sinusitis was delayed because a routine computerized tomographic scan was normal. This case underscores the importance of specifically requesting views of the paranasal sinuses in suspected cases of sinusitis. Key words * sphenoid sinusitis * neurodiagnostic imaging
Complications from sphenoid sinusitis, such as irreversible visual loss, cranial nerve palsies, orbital or intracranial abscess, meningitis, cavernous sinus or carotid artery thrombosis, and even death, may be prevented by early detection and treatment of sphenoid sinusitis. 1-4 However, the diagnosis of isolated sphenoid sinusitis is often delayed because of misdiagnosis. In the following case, the diagnosis was considered but was initially missed because the physician ordered a routine cranial computerized tomographic (CT) scan, which did not provide adequate views of the paranasal sinuses.
CASE REPORT A 13-year-old boy received a 1-week course of oral
From the Neuro-Ophthalmology Division, Department of Ophthalmology, Pennsylvania State University, Hershey, Pennsylvania. Requests for reprints should be addressed to Dr Lenworth N. Johnson, Neuro-Ophthalmology Division, Mason Institute of Ophthalmology, University of Missouri-Columbia, Columbia, MO 65212. JOURNAL OF THE NATIONAL MEDICAL ASSOCIATION, VOL. 83, NO. 1
erythromycin for severe, right, retro-orbital and frontal pain thought to be due to sinusitis. Radiologic studies of the paranasal sinuses were not obtained prior to antibiotic initiation. Despite the antibiotic, the pain persisted, and the patient developed a low grade fever and horizontal diplopia. His examination was normal apart from his ill appearance, low grade fever, and right abducens nerve paresis. Laboratory studies showed increased Westergren sedimentation rate to 38 mm/hr and elevated leukocyte count to 14 000 cu/mm. A routine, cranial CT scan was normal. Opening pressure on lumbar puncture and cerebrospinal fluid analysis were normal. Neuro-ophthalmologic consultation, obtained one day after the above studies, confirmed the right abducens nerve paresis. On review of the initial, routine CT scan, it was noted that views of the paranasal sinuses were not provided. A second CT scan with coronal views of the paranasal and cavernous sinuses was then performed. This scan demonstrated opacified sphenoid sinuses without airfluid level and possible extension of inflammation to the right cavernous sinus (Figs I & 2). Intravenous ceftriaxone was instituted. The patient became asymptomatic, with complete resolution of the abducens nerve paresis occurring within 1 week. Intravenous ceftriaxone was discontinued and treatment with oral amoxicillin/clavulanate potassium was continued for 3 weeks. A follow-up CT scan of the paranasal sinuses following cessation of antibiotics showed marked improvement of the sphenoid sinus opacification.
DISCUSSION Neurodiagnostic imaging is not indicated for all cases of sinusitis. Plain radiographs of the paranasal sinuses may be helpful in documenting sinus opacifica85
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Figure 1. Coronal computerized tomography scan demonstrating bilateral sphenoid sinus opacification (arrows) suggestive of sphenoid sinusitis.
tion or air-fluid level suggestive of sinusitis. However, plain sinus radiographs are not as sensitive for detecting paranasal sinusitis as the CT scan.5 Hence, in patients with neurologic signs, such as the abducens palsy our patient showed, a CT scan is indicated. When CT scans are ordered, clinicians should be aware that routine, cranial CT scans may not provide adequate views of the paranasal sinuses.6 The clinicians ordering these studies should specifically request axial and direct coronal views of the paranasal sinuses. Sinus opacification may suggest sinusitis with diffuse mucosal thickening or fluid, chronic osteitis, soft tissue mass, or may also be seen in clinically normal individuals.7 Thus, following the administration of appropriate antibiotics, persistence of clinical signs or symptoms may warrant a second CT scan or magnetic resonance imaging of the paranasal sinuses.8,9
Figure 2. Coronal computerized tomography scan demonstrating suspected extension of inflammation to the right cavernous sinus (arrow) accounting for the right abducens nerve paresis. 2. Slavin ML, GlaserJS. Acute severe irreversible visual loss with sphenoethmoiditis-"posterior" orbital cellulitis. Arch Ophthalmol. 1 987; 1 05:345-348. 3. Sofferman RA. Cavernous sinus thrombophlebitis secondary to sphenoid sinusitis. Laryngoscope. 1983;93:797-800. 4. Marks PV, Furneaux CE. Pituitary abscess following asymptomatic sphenoid sinusitis. J Laryngol Otol. 1984;98:1 151-1155. 5. Sanborn GE, Kivlin JD, Stevens M. Optic neuritis secondary to sinus disease. Arch Otolaryngol. 1984;1 10:816-819. 6. Johnson LN, Krohel GB, Yeon EB, Parnes SM. Sinus tumors invading the orbit. Ophthalmology. 1984;91 :209-217. 7. Diament MJ, Senac MD, Gilsanz V, et al. Prevalence of incidental paranasal sinuses opacification in pediatric patients: a CT study. J Comput Assist Tomogr. 1987;1 1:426-43 1. 8. Moore J, Potchen M, Sierra A, Waldenmaier N, Potchen EJ. High-field magnetic resonance imaging of paranasal sinus inflammatory disease. Laryngoscope. 1986;96:267-271. 9. Slamovits TL, Gardner TA. Neuroimaging in neuroophthalmology. Ophthalmology. 1989;96:555-568.
Literature Cited 1. Holt GR, Standefer JA, Brown WE, Gates GA. Infectious diseases of the sphenoid sinus. Laryngoscope. 1 986;94:330335.
JOURNAL OF THE NATIONAL MEDICAL ASSOCIATION, VOL. 83, NO. 1

domain: health


text:
Summer is a time for most high school students to put the books away and get as far away from their school as possible, but students in Legend High School’s theater are spending their “vacation” working, rehearsing and learning a new …
Summer is a time for most high school students to put the books away and get as far away from their school as possible, but students in Legend High School’s theater are spending their “vacation” working, rehearsing and learning a new language.
The cast and crew of “Tribes,” a British play about a young woman dealing with a gradually losing her hearing, have all been learning American Sign Language to give the production authenticity and show respect to the deaf community, a larger community than many of the students, staff or audience members may realize.
“I had no idea how many people in my life are dealing with progressive hearing loss,” said Bennie Palko, technical theater director at Legend and director of the show. “I find a new person once a week.”
Only one of the students involved was fluent in ASL when rehearsals began. The rest have taught themselves along the way. Cast and crew have been using the Marco Polo app to send each other video messages in ASL, and each student had to learn to sign a song of their choice. Palko’s friends and others fluent in sign language will be watching run-throughs to make sure characters are portrayed accurately and using correct grammar.
“Grammar is funky,” said Aliza Ilano, a senior portraying the female lead, Sylvia. “I want to give the justice to the character that she deserves.”
In the play, Sylvia, whose family members are all deaf, begins losing her hearing and meets Billy, the only deaf member of a family that insisted he always speak and read lips, rather than learn sign language. Sylvia teaches Billy ASL, causing characters to confront themes of discrimination, prejudice, family and communication.
“It’s a story that every family with a deaf child goes through, whether it’s the acceptance or denial,” said junior Greyson Nicholson, who plays Billy.
Much of the dialogue in the play is signed by the characters, and some scenes will feature projected subtitles to help the audience follow along. Some scenes won’t, Palko said, so the audience can get a sense of the disconnected feeling a deaf person has when interacting with people who don’t speak ASL.
Ilano said she hopes those scenes, and the play as a whole, open audience members up enough to try to see, and hear, things in a different way.
“It will be a little uncomfortable for people,” she said. “But it’s a good kind of uncomfortable.”

domain: artistic


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[Photo by Sam Erickson]
Download: Elvis Perkins - "While You Were Sleeping"
This week's Song of the Week is tardy because I was in San Diego running a marathon. Better late than never, I say.
FJ recently nominated Bright Eyes' "If the Brakeman Turns My Way" as a future Song of the Week, and while I love the song and may consider it for a future installment, I am instead going to choose a different artist and song FJ brought to my attention: Elvis Perkins's "While You Were Sleeping."
Practically every piece of media on Perkins mentions his Hollywood heritage--the son of Psycho star Anthony Perkins and photographer Berry Berenson--and the fact that both of his parents endured notable deaths, his father from AIDS-related causes and his mother as a passenger on American Airlines flight 11, which crashed into the World Trade Center on 9/11. The fascination with his backstory would be mere media nosiness if it wasn't for the fact that Perkins, himself, seems to reference his parents' deaths in his songs. "While You Were Sleeping," in particular, seems to address 9/11:
While you were sleeping
You tossed, you turned
You rolled your eyes as the world burned
The heavens fell, the earth quaked
I thought you must be, but you weren't awake
It's not simply about 9/11, but as the opener to his debut, Ash Wednesday, the song establishes the album's predominant theme of the soul's resilience in the face of unquantifiable grief. "While You Were Sleeping" and the album's other songs are indelibly melancholy but it is a testament to Perkins's songwriting and singing that they never verge on depressing. Perkins's voice has a lazy, wearied quality that sounds resigned to the trials and tribulations of life, and the songs, rather than surrender to the hardship of life, affirm the virtue of living even in the presence of heartwrenching loss.
"While You Were Sleeping" is my favorite song from the album. For a while I thought it was the title track, but "While You Were Sleeping" is a hypnotic, haunting lullaby that I can't get out of my head. It starts quietly and gradually builds, instrument by instrument, but never rises above a well-paced amble to become a comforting, suprisingly inspirational song. It comes to life near the end when horns carry Perkins's words towards a flowing stream of imagery, the song rushing forward as Perkins sings, "Thank God you're up now/Let's stay this way/Else there'll be no more mornings/And no more days." And when the song drifts off it does so with a sweetly pained series of "oh's".
The song, from what I gather, is about all the things--the very imminent to the distant--that loom over us in our daily lives. It's also about what is missed in life ("While you were sleeping/ Your babies grew") and how the most significant events in life transpire while we have our eyes closed. Perkins's impressionistic lyrics don't offer direct explanations, but they do offer suggestive images of life that is unpredictable yet fair. Ultimately the song is a carpe diem song minus the overzealous optimism. Life can be harsh, Perkins argues, but the best way to cope is to simply live on.
[Note: It seems fitting that I fell asleep while trying to post this late Monday night.]


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I’m just tired; I just want the world to be quiet for a bit. - (via reckless-and-kerosene)
I’m really afraid to feel happy because it never lasts. - Andy Warhol (via felicefawn)
I need someone who’s okay with laying in bed all day but also up for spontaneous adventures.
I gave wrong people the right pieces of me. -
My life story.


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lovely blooms - card ideas . Love the flourish and adding a few small flowers. Simple and elegant.
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Nicola Curry was born in 1986 in Baltimore, Maryland and began dancing at the age of three. At five, she moved to Colorado Springs, Colorado with her family, and at fourteen, attended the National Ballet School in Toronto, Canada for four years. While at the National Ballet School, Curry won the Peter Dwyer Dance Scholarship awarded for excellence by the Canadian Council for the Arts. Upon graduating in 2004, she was awarded the Erik Bruhn Memorial Award for excellence in ballet.
Curry joined the American Ballet Theatre Studio Company in 2004. In May 2005, she joined the main company as an apprentice, and the corps de ballet in March 2006. While at the American Ballet Theatre, Curry flourished and was featured in a variety of soloist and principal roles.
In January 2015, Curry moved to Melbourne, Australia with her husband and joined The Australian Ballet. In 2017, she was promoted to soloist with the company and has been featured in a variety of principal roles since joining the company.
Curry’s choreographic success began in 2010 with her first ballet, choreographed for the American Ballet Theatre’s Innovation Initiative. This performance led to several commissions including a pas de deux for ABT for the International Erik Bruhn Competition in Toronto, Canada, and an additional pas de deux for The Young Choreographer’s Showcase in New York. Most recently she choreographed and directed the acclaimed jewelry company Dannijo’s New York Fashion Week presentation.
Curry danced with the American Ballet Theatre for nine years. She has recently gotten married and has moved to Australia with her husband. She joined The Australian Ballet in Melbourne, Australia as a ballerina in January 2015.


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2 Hospitalized After Collision Near Lyons Avenue
Newhall, CA (October 18, 2022) – Two people suffered injuries following a traffic accident that occurred on 5 Freeway.
Auto vs. Big Rig Accident on 5 Freeway in Newhall
According to KHTS News, a collision between a big rig and a Honda Accord took place in the northbound side of the freeway; just south of Lyons Avenue.
Earlier reports indicated the driver of the Honda lost control while driving on I-5. Subsequently, the car slammed into the back of the semi truck. The force from the impact left the Honda pinned underneath the big rig. Several other cars got involved in the mishap.
Shortly after 4:30 p.m., rescue teams arrived at the location. Responding paramedics rendered aid to the all possible victims in the crash. After the evaluation, authorities confirmed two people suffered injuries as a result of the wreck. Medical personnel transported the injured parties to a hospital for further treatment and evaluation.
Several factors surrounding the incident remained unclear. At this time, detectives continue to investigate the precise cause of the traffic collision that happened on 5 Freeway in Newhall.
Source: KHTS News
“The Johnson Attorneys Group does not represent any of the parties mentioned above. Furthermore, the Johnson Attorneys Group also does not intend to represent any of the parties discussed. If you would like to contribute any information or have any concern with this story, please contact us as soon as possible.”
- Geoffrey Balzer Killed in Coalinga Crash on Interstate 5 - June 9, 2023
- Richard Coin Killed in Oroville Pedestrian Accident on Olive Highway - June 9, 2023
- Stanislaus County Car Crash at Patterson Road and Skittone Road - June 9, 2023

domain: law


text:
Intense Debate: In 2024, the Turnpike’s New Year’s Toll Increase is More Substantial
CheapNailsalonsnearme– The Ohio Turnpike and Infrastructure Commission’s announcement of a toll hike for 2024 has sparked a heated discussion among the public. This increase, ranging between 6.8% and 8.1%, marks the 12th consecutive year of such hikes. The rationale behind this decision is the escalating costs associated with highway and bridge maintenance.
Notably, drivers using small vehicles without electronic tolls will experience the highest increase, with a full-length trip cost rising from $21.50 to $23.25. Conversely, E-ZPass users will see a smaller rise, from $14.75 to $15.75. Public reactions vary significantly.
Some express frustration over the continued existence of tolls, especially since the Ohio Turnpike was completed in 1955. They argue that the tolls should have been removed after the turnpike’s costs were recuperated. Others express skepticism towards the E-ZPass system, questioning its cost-effectiveness for infrequent users.
However, a segment of the population understands the necessity of these increases for the maintenance and improvement of the roads, calling for more transparency in the allocation of these funds. The article invites readers to share their opinions on these issues, encouraging a broad spectrum of views on the toll hike, the E-ZPass system, and the demand for greater transparency in the use of toll funds.


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Oh soup, how we love thee! I don't like much about cold weather, but the fact that it is soup season, is one reason I look forward to it.
When it is cold outside, there isn't a week that goes by that we aren't sitting down to a warm bowl of goodness at least once, sometimes more.
When I have the chance to take a classic, like tomato soup, and pump up the nutrition, and put a tasty twist on a it, well that's even better.
There is one rule about this soup though...you CANNOT serve it without some hot grilled cheese sammies for dipping! It's just not allowed!
On a fall day, let your family come home to this delicious soup...you'll be a hero!
Related: Our Best Soup Recipes
- Cook Time
- 4 cups vegetable juice
- 1 (32-oz) bag frozen mixed veggies
- 1 (6 oz.) can tomato paste
- 1 (14 oz.) can chicken broth
- 3 cups water
- 1 tsp. garlic powder
- 1 tsp. Italian seasoning
- ½ cup finely chopped onion
- dried parsley
- salt and pepper to taste
Add all ingredients to slow cooker. Stir to combine. Cook on LOW 6 hours or until heated through. Garnish with dried parsley.


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A military judge has rejected a request for war court intervention in the healthcare of an alleged 9/11 plotter who, according to his lawyer, still suffers from wounds inflicted at a CIA “black site” where agents subjected him to rectal rehydration.
Army Col. James L. Pohl wrote in a two-page order released by the Pentagon Friday that the court “does not have the authority to address issues concerning medical care.” It was dated March 10.
In February, the attorney for Saudi captive Mustafa al Hawsawi asked the judge to intervene in the case, referring to a recently released portion of the Senate Intelligence Committee's “Torture Report,” and saying that the 46-year-old man had been rectally abused while in CIA custody — and that he continues to bleed now, at least eight years later.
“Some would call that sodomy,” said attorney Walter Ruiz, adding that “those acts caused longstanding chronic medical conditions that have yet to be resolved.”
Hawsawi is accused of helping the Sept. 11 hijackers with travel and money. He is awaiting a death-penalty trial with the alleged mastermind, Khalid Sheik Mohammed, and three others, all of whom were subjected to “enhanced interrogation techniques” before they got to Guantánamo in September 2006.
Hawsawi has sat on a pillow over years of pretrial hearings. The February hearing was the first time that Ruiz was permitted to explain it under a loosening of censorship at the court that lets lawyers talk about the released, redacted 524-page portion of the 6,200-page Senate report.
Guantánamo’s prison spokesmen say war-on-terror captives get the same level of medical care as U.S. service members.
Ruiz specifically cited a reference to an investigation of allegations that CIA agents conducted medically unnecessary rectal exams with excessive force on two detainees, one of them Hawsawi, who afterward suffered an anal fissure, rectal prolapse and hemorrhoids.
Ruiz said that guards sometimes find blood in Hawsawi’s clothes. The lawyer asked the judge to order prison legal and medical staff to speak with him, as Hawsawi’s healthcare proxy, and to let him see Hawsawi’s secret medical records.
Prosecutors urged the Army judge to stay out of the issue. “No doctor should be treating with a lawyer looking over his shoulder,” said federal attorney Ed Ryan.
The Sept. 11 hearings are in recess until April 20.
Follow @CarolRosenberg on Twitter
The Miami Herald guide to the Sept. 11 war crimes trial here.

domain: news


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Tomato and Basil Spaghetti Squash Bake. +1 For Being A Healthy Vegetarian Recipe! Nice and filling!
Tomato & Basil Spaghetti Squash Bake
Fried green beans are the healthy alternative to regular french fries. These are equally tasty and go wonderfully with cold beer. These are so good that even the veggie haters will love them! | giverecipe.com | #greenbeans #summerrecipes #friedgreenbeans #greenbeansrecipes #vegetarian #glutenfree
Fried Green Beans - Give Recipe
Loaded Cauliflower Casserole--It's like macaroni and cheese but with cauliflower instead.
Cauliflower "Mac" and Cheese Casserole Recipe : Food Network
21 Ideas For Energy-Boosting Breakfast Toasts
Infused Waters to Keep You Hydrated this Summer - Tasty Yummies
Diabetes-Friendly Mac and Cheese Recipes | Diabetic Living Online
Diabetes-Friendly Mac and Cheese Recipes
Top 25 Diabetic Snacks | Diabetic Living Online
Top 25 Diabetic Snacks
13 Quick and Easy Snacks for Diabetics
Photo Gallery: Diabetes Easy Snacks
Twice Baked Cauliflower - tastes the same as twice baked potatoes but aren't loaded with carbs!! Recipe from Kalyn's Kitchen"
Kalyn's Kitchen®: Twice-Baked Cauliflower (Low-Carb, Gluten-Free)
Effective Home Remedy for Sore, Cracked and Stinky FeetMix 1/4 c Listerine (any kind but I like the blue), 1/4 c vinegar and 1/2 c of warm water. Soak feet for 10 minutes and when you take them out the dead skin will practically wipe off. Home Remedies, Soak Feet, Foot Soak, Stinky Feet, Diy Crafts, Flip Flops, Warm Water, Crack Feet, Dead Skin
Effective Home Remedy "Flip Flop Feet": Mix 1/4 c Listerine (any kind but I like the blue), 1/4 c vinegar and 1/2 c of warm water. Soak feet for 10 minutes and when you take them out the dead skin will practically wipe off.
Dijon Beef & Mushrooms Skinny Slow Cooker Recipes
Thai Green Curry Chicken - In only 35 minutes, you can be indulging in this restaurant-worthy recipe. Coconut milk offers a bit of sweetness to help balance the classic Thai flavors. More low-cal recipes: http://www.bhg.com/recipes/healthy/dinner/healthy-chicken-recipes/ Thai Green, Coconut Milk, Chicken Curries, Healthy Eating, Healthy Dinner, Healthy Chicken Recipes, Healthy Recipe, Curries Chicken, Green Curries
Thai Green Curry Chicken - In only 35 minutes, you can be indulging in this restaurant-worthy recipe. Coconut milk offers a bit of sweetness to help balance the classic Thai flavors. More low-cal recipes: www.bhg.com/...
healthy dinner: lemon risotto with asparagus
15-Minute Meals: Easy, Healthy Dinner Recipes (Chicken Masala with Jasmine Rice and Peas)
Approximately 110 calories each! Low-cal Mini Turkey Meatloaves With Chipotle Glaze, via @WaspyRedhead... Healthy dinner recipe
almond butter & banana sandwich. Tastes pretty damn awesome if I dare say so! It will power your morning and give your body a lot of nutritious goodness. Healthy Snacks, Morning Snack, Healthy Breakfast, Mornings Power, Almond Butter, Power Snacks, Healthy Mornings, Peanut Butter, Healthy Treats
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Almond butter and banana open sandwich
Super Easy Crock Pot Spaghetti Squash with Meatballs! Just three ingredients, 3 hours, and the best squash I have ever tasted!!
White Chocolate Rocky Road - Recipes, Dinner Ideas, Healthy Recipes & Food Guides
Butter-Pecan Sweet Potatoes - Recipes, Dinner Ideas, Healthy Recipes & Food Guides
Cheesy Squash Casserole - Recipes, Dinner Ideas, Healthy Recipes & Food Guide
Exclusive Foods: Easy Slow Cooker Taco Pasta# slow cooker healthy recipes
Steak and Spinach Quesadilla with Provolone | Simple Dish | Quick, Easy, & Healthy Recipes for Dinner
Zucchini Cakes....just 63 calories :) Each scrumptious morsel is totally satisfying and packed with vitamin-rich zucchini, yet strikingly low in calories, carbs, and fat.
Spinach, Ricotta & Pesto Lasagna - A delicious and cheesy vegetarian lasagna


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Playlist: Songs Ruined by Retail
Lose your faith in humanity and G-Rated songs for $14.60 an hour
I have fond memories of my ‘First Five Jobs’. Maybe it’s nostalgia talking but the worst of the customers have now become funny anecdotes, the Saturday morning shifts with a Castle Hill RSL hangover are forgotten, and trying to get an assignment while manning a register is a skill I long forgot.
Although I don’t stress about attach rates or swapping shifts anymore, two things have stuck with me — a bunch of amazing friends, and a reflexive anger that emerges when I hear the songs below.
Why am I angry? (the almost criteria)
The song was either
Played far too much over the years
OR was so distinctively different than the other songs that played before or after it that you noticed it every time
OR customers commented on the song every time it played.
Understanding this is purely an emotional criteria - ‘this song makes me ill as a result of my retail experience’ - for a bit more context below is what my LinkedIn would have looked like in 2012.
Coles — Deli service. Bunnings Warehouse — Hardware ‘expert’, Apple Retail — Not a Genius, Michael Hill — Not a jeweller, Apple Retail — Still Not a Genius
Why did I create this playlist of songs I hate? Two reasons.
- Some people like Coles’ music selection enough that now you can stream it online. I wish I was kidding.
- It allows me to set a rule that these songs are not to be played by Apple Music or appear in other playlists (also works for holiday songs).
Songs 19. 1 Hour 13 Minutes.
The Highlights (Lowlights)
I wear headphones in supermarkets purely in fear of hearing this song over the sound system.
When this song came on for the third time on a Saturday I would, out of the goodness of my heart, stop whatever I was doing and read the Flybuys plug and the promotions of the day. Just so my co-workers would not have to listen to this song. Again.
“.. and in our Deli today, we have venemai prawns for $9.98 per kilo.”
Thankfully, I can now drink sufficient amounts of alcohol in bars to smile and sing the occasional chorus. Enough to not look un-Australian anyway.
This is a bland song with a catchy chorus, so naturally every grocery, hardware and specialist retailer has at some point had this on their playlist.
Then they forgot it was there.
10 years later it still plays every 2–3 hours, and your customer will tell you how much they like this song as soon as it hits the first “That may be all I need..”.
I went to a wedding once where the Bridal party walked into the reception to this song. Sixteen and stoked to be drinking champagne, the moment was ruined when this song started playing.
Anytime I hear it I’m suddenly thrown back to seasoning raw Chicken in a Coles Deli.
It was gross. This song is gross.
This is an annoying song. I’ve never heard a positive thing about this song. Hear this song every three and a half hours and you will loathe this song.
Made worse by the fact that when it’s bookended by a chill singer-songwriter track and a 70’s pub rock song it sticks out like a sore thumb.
Hearing the opening sends a shudder down my spine.
“Why anyone thought that need a shitty lounge cover, and why anyone thought said lounge cover should be played in a hardware store I will never know”
A friend of mine put it better than I ever could.
What’s special about this particular song is that it was played in every single one of my first five. Because nothing crosses differences in stock and target market like an acoustic rendition of a Foo Fighters classic.
I’m not sure if you remember but this song was more overplayed that Gotye ever was.
I remember clearly the stages of being overplayed in 2006
- Song is played on the O.C
- Becomes popular amongst fellow 16 and 17 year old girls
- Picked up by non-Triple J radio
- Keeps getting radio play to meet Australian representation requirements
- Appears on Coles Radio
Unfortunately I suffered through all of it, and christ do I hate this song.
This one really grinds my gears. I love the Beatles. I’ve listen to their albums in my car on regular rotation since I realised I never sped while listening to Rubber Soul, Sergeant Pepper’s or Abbey Road. I can speak for hours on the band’s influence on music.
So on my birthday when The Beatles were announced on iTunes, I was stoked to receive an Abbey Road lanyard, be greeted by life size figures of John, Paul, Ringo and George and hear a band I loved playing exclusively on the store stereo.
And they blew it. Want to make anyone hate The Beatles? Pick 8 random songs from their discography and play them on repeat for two months as your staff work 10+ hour days in the Holiday season. Thanks Apple. RUINED.
At least Apple played decent Christmas Music. Only every third song was ever a carol and they were usually something a bit more bearable than another Bieber, Buble or Crosby. For every other retailer November 2 signals the beginning of retail hell with angsty and angry customers, extended opening hours and too much overtime.
To rub salt in the wound the whole season is soundtracked (is this a word?) by the same 5 songs, interpretted by pop artists from various decades.
Okay this is technically my own fault. This is a terrible song to have as your morning alarm to wake you up at 6am for a Saturday morning shift at the local hardware store.
Or worse, on a summer public holiday. They never were worth the penalty rates.
Like this article? Check out another one of my playlists


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Many people have hip problems later in life, which sometimes leads to hip replacement surgery. But if you catch hip problems earlier, you may not have to undergo such a radical procedure.
Dr. Parth Lodhia is an expert in hip arthroscopy, a minimally invasive procedure which looks to do “joint preservation instead of replacement.”
tap here to see other videos from our team.
Lodhia will be heading a new team at Eagle Ridge Hospital in Port Moody performing the surgery, which is only done at a handful of hospitals in B.C.
Philanthropists Ray Bergen and Eric and Jennifer Martin donated $30,244 to buy special equipment to get the program running.
“I’m so thrilled that this is finally coming to fruition,” said Lodhia. “I wanted to come here and serve this population of athletic young individuals with hip pain who may not have had great options going for them.”
A news release from Eagle Ridge Hospital explains the surgery involves making “small incisions into the joint and inserting an ‘arthroscope’ (an instrument containing a lens, light source and video camera) to assess the hip joint damage and repair injured structures simultaneously.”
The procedure may take only a couple of hours, and patients can go home afterwards.
“This is mainly to try and preserve the joint, and to try and improve the patient’s quality of life and pain,” said Lodhia. “Generally speaking the best target group is adolescents to the 20s, because that’s when we can change the trajectory of the hip. Somebody a little farther along in their path in life, their trajectory is already set.”
Many of the people with hip problems at such a relatively young age are athletes.
“The classic scenario is the hockey goalie who goes into the butterfly position 200 times every practice or game,” he said. “You can imagine, those hips go through a lot. You can now start compounding the amount of practices they had during adolescence, then making a team. Add every week and every year and you can imagine how many times their hips go through that motion. It keeps hitting, one bone hits the other bone, and it starts to create issues.
“Similarly with skiing. You’re in a bit of a crouched position, that starts to create problems. Or if you take a jump and that rams one bone into the other you can have symptoms.
“The majority of these problems can be managed without surgery. But if somebody does need surgery, there’s no point in making them wait.”
Lodhia is only 38 but has extensive experience in his field. He graduated from the University of B.C. medical school in 2007 and spent five years there doing an orthopedic surgery residency. In 2012, he got an orthopedic sports medicine fellowship at the Baylor College of Medicine in Houston, Tex.
“That was a pretty neat experience, I got to work with the NFL Texans, the Major League Baseball Houston Astros and the NBA’s Houston Rockets,” he said.
He came back to B.C. but then left for another fellowship at the American Hip Institute in Chicago.
“In my fellowship, we actually had three rooms going, two-or-three rooms and we’d just bounce back and forth, doing anywhere from six to eight a day,” he relates. “They had it dialed in.”
He could have stayed in the U.S. and been in the vanguard of hip treatment: “If you want to be an innovator the sky’s the limit.”
But he chose to come back to Canada with his wife and son. (The couple is also expecting a baby.)
“There was something about Vancouver, I just gravitated back,” he said. “My family is here, first and foremost. My grandpa is also living with us, so we have an 86-year-old and a four-year-old in the same house.
“That sense of community and social responsibility sort of brought me back. This is where I started — I was given a chance here, I should come back and share what I’ve learned. Hopefully I can make some difference.”

domain: medical


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From Maine, USA:
I have a 4 year old that has been experiencing problems with low blood sugar at the onset of an illness. He gets the ketone breath and pale and lethargic. Any suggestions? His doctors says just to give orange juice at this time. Anything else we should be concerned with?
This is a common problem that sometimes requires some rather careful balancing. The initial low blood sugar is because his caloric intake has gone down in relation to his insulin dose. The problem is that you need to maintain or even increase the insulin in order to deal with the ketosis so the answer is, as your doctor suggests, to keep the glucose up with orange juice or glucose gel into the cheek pouch. Besides that, lots of blood sugar estimations and ready telephone access to a diabetic team are what matters.
Original posting 12 Jun 1999
Posted to Hypoglycemia
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Last Updated: Tuesday April 06, 2010 15:09:04
This Internet site provides information of a general nature and is designed for educational purposes only. If you have any concerns about your own health or the health of your child, you should always consult with a physician or other health care professional.
This site is published by T-1 Today, Inc. (d/b/a Children with Diabetes), a 501c3 not-for-profit organization, which is responsible for its contents. Our mission is to provide education and support to families living with type 1 diabetes.
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How Materials Become Magnetized
Ferromagnetic materials, such as iron, nickel, and cobalt, undergo magnetization when exposed to the magnetic field of a magnet. For instance, a permanent magnet can attract and magnetize objects like paper clips, nails, or iron filings. In this process, the object not only becomes attracted to the magnet but also acquires magnetism itself. However, this magnetism tends to diminish when the object is removed from the magnetic field.
The magnetic properties of the material impact both the magnetic flux density at the poles and the way flux density decreases with distance from the poles. Physical size also plays a role in flux density; for example, two disk magnets made from sintered Alnico may have similar densities near the pole, but the larger magnet exhibits higher flux density as you move away from the pole. This type of information is crucial for determining the effectiveness of a magnet in specific applications, especially considering the working distance.
Ferromagnetic materials possess minute magnetic domains formed within their atomic structure due to the orbital motion and spin of electrons. These domains can be visualized as very small bar magnets with north and south poles. In the absence of an external magnetic field, these domains are randomly oriented (Figure 1a). However, when the material is introduced into a magnetic field, the domains align themselves (Figure 1b), turning the object into a magnet.
The Hall Effect
The Hall effect is a phenomenon where a small voltage (a few volts) is generated on opposite sides of a thin current-carrying conductor or semiconductor known as the Hall element, which is placed in a magnetic field. This results in the appearance of a voltage called the Hall voltage across the Hall element. The Hall voltage is a consequence of the forces acting on electrons as they move through the magnetic field, leading to an accumulation of charge on one side of the Hall element. Although the effect was initially observed in conductors, it is more pronounced in semiconductors, which are commonly used in Hall-effect sensors.
In Hall-effect sensors, the magnetic field, electric current, and Hall voltage are all perpendicular to each other (as illustrated in Figure 2). This voltage can be amplified and utilized to detect the presence of a magnetic field, making it valuable in sensor applications.
Hall-effect sensors are favored for their small size, affordability, and lack of moving parts. They are non-contacting sensors, which contributes to their durability over numerous operations—a significant advantage over contacting sensors that may wear out. These sensors can detect the proximity of a magnet by sensing its magnetic field, making them suitable for position measurements or motion sensing. They are often employed in combination with other sensor elements for measuring current, temperature, or pressure.
The automotive industry extensively uses Hall-effect sensors for various purposes such as measuring throttle angle, determining crankshaft and camshaft positions, monitoring distributor position, tachometer readings, and gauging power seat and rear-view mirror positions. Additionally, these sensors find applications in measuring parameters for rotating devices like drills, fans, flow meter vanes, and disk speed detection.
Back EMF in DC Motors
When a DC motor is initiated, a magnetic field is established by the field windings. The armature current generates an additional magnetic field that interacts with the field winding’s magnetic field, initiating the motor’s rotation. As the armature windings start to spin within the magnetic field, generator action occurs. In other words, the rotating armature produces a voltage across it, which opposes the original applied voltage, following Lenz’s law. This self-generated voltage is termed “back electromotive force” or back EMF.
While the term “electromotive force” (EMF) was historically used for voltage, it is now less favored due to the recognition that voltage is not a “force” in the physics sense. However, “back EMF” is still employed to describe the self-generated voltage in motors. Back EMF, also known as counter EMF, plays a crucial role in reducing armature current when the motor is operating at a constant speed. It acts as a counteracting force to the applied voltage, limiting the flow of current in the armature windings as the motor reaches a stable rotational speed. Understanding and managing back EMF is essential in designing and controlling DC motors effectively.
Glossary of Electromagnetic Terms
Ampere-turn (At): The SI unit of magnetomotive force (mmf).
Electromagnetic field: A formation of a group of magnetic lines of force surrounding a conductor created by electrical current in the conductor.
Electromagnetic induction: The phenomenon or process by which a voltage is produced in a conductor when there is relative motion between the conductor and a magnetic or electromagnetic field.
Electromagnetism: The production of a magnetic field by current in a conductor.
Faraday’s law: A law stating that the voltage induced across a coil equals the number of turns in the coil times the rate of change of the magnetic flux.
Gauss: A CGS unit of flux density.
Hall effect: A change in current density across a conductor or semiconductor when current in the material is perpendicular to a magnetic field. The change in current density produces a small transverse voltage in the material, called the Hall voltage.
Hysteresis: A characteristic of a magnetic material whereby a change in magnetization lags the application of the magnetic field intensity.
Induced current (i ind): A current induced in a conductor as a result of a changing magnetic field.
Induced voltage (v ind): Voltage produced as a result of a changing magnetic field.
Lenz’s law: A physical law that states when the current through a coil changes, the polarity of the induced voltage created by the changing magnetic field is such that it always opposes the change in current that caused it. The current cannot change instantaneously.
Lines of force: Magnetic flux lines in a magnetic field radiating from the north pole to the south pole.
Magnetic field: A force field radiating from the north pole to the south pole of a magnet.
Magnetic flux: The lines of force between the north and south poles of a permanent magnet or an electromagnet.
Magnetic field intensity: The amount of mmf per unit length of magnetic material.
Magnetomotive force (mmf): The cause of a magnetic field, measured in ampere-turns.
Permeability: The measure of ease with which a magnetic field can be established in a material.
Relay: An electromagnetically controlled mechanical device in which electrical contacts are opened or closed by a magnetizing current.
Reluctance ( ): The opposition to the establishment of a magnetic field in a material.
Retentivity: The ability of a material, once magnetized, to maintain a magnetized state without the presence of a magnetizing force.
Solenoid: An electromagnetically controlled device in which the mechanical movement of a shaft or plunger is activated by a magnetizing current.
Speaker: An electromagnetic device that converts electrical signals to sound waves.
Tesla (T): The SI unit of flux density.
Weber (Wb): The SI unit of magnetic flux, which represents lines.


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Come March 24 and 25, the Rosenbach Museum is hosting Sendak in Spring: A Program for Families, a celebration of the famed author of Where The Wild Things Are that includes an “interactive” and “imaginative” sing-along, the “The Wild Things Whirligig!”
What the Rosenbach left out of their program description notes, however, is that while Sendak doesn’t exactly hate children, he also doesn’t much care for people in general. In an interview last year with The Guardian, Sendak revealed that he hates Gwyneth Paltrow, and he’s happy Roald Dahl is finally dead. Elsewhere: “I love animals — I love animals much more than I love human animals.” Oh, and he’s batshit crazy, by his own admission.
From The Guardian:
I’m totally crazy, I know that. I don’t say that to be a smartass, but I know that that’s the very essence of what makes my work good. And I know my work is good. Not everybody likes it, that’s fine. I don’t do it for everybody. Or anybody. I do it because I can’t not do it.”
What finally makes Sendak such a aberration in the PC world of kiddie lit can be boiled down to this gem of a quote: “I refuse to cater to the bullshit of innocence.” A Sendak-inspired children’s opera? We expect it to be rife with death and Blakeian madness, and close with a collective tiny middle-finger raising to the author himself, should his critics be so moved.


Brave Raccoon Hitches A Ride On An Alligator
The world’s bravest raccoon hitches a ride on an alligator in Florida. Richard Jones was visiting Ocala National Forest when he spotted something strange in the Ocklawaha River — a raccoon riding an alligator.
Elephant Graffiti Art In South Africa To Give People Hope
From the 13th of May to the 31st of October last year, Cape Town graffiti artist Falko painted his way across South Africa. His mission? To change the locals’ perception of value. The project, called “Once Upon A Town,” was photographed by Luke Daniel.
Brave Egret Rides On The Back Of Alligator
This brave egret picks an unlikely perch to stand on while looking for her lunch – the back of an alligator. Luckily for the brave egret, the big gator barely moved a muscle and let her observe the water before she flew off to a…
Daring Damselfly Rests Inside Crocodile’s Open Jaw
A green damselfly decides to rest on a rather dangerous perch – a young crocodile’s open jaw. The female crocodile was sunning itself when a brave insect decided to land on the reptile’s head before moving down to its snout.
Delicate Handmade Glass Animal Sculptures
Ukrainian glass artist Nikita Drachuk creates mind blowing handmade glass animal sculptures. Her delicate glass animal sculptures include spiders, grasshopper, octopi and other critters. He uses as method called lampworking, where a lamp or torch is used to melt rods of colored glass. Once in…


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Synairgen shares shot up in July 2020 as it announced the discovery of a promising new pandemic treatment. But phase III trial results of its SNG001 medication yielded unexpectedly poor results yesterday.
Synairgen (LON: SNG) shares were of the winners of the covid-19 pandemic, soaring from 5p at the end of 2019 to 247p by August 2020. But after experiencing extreme volatility, the biotech stock fell to 172p last Friday. And then yesterday, disaster struck. The Synairgen share price collapsed by 94% to 13p, as its proprietary covid-19 medication yielded disappointing trial results.
However, Synairgen shares have now recovered to 26p, as a home-based trial could still yield results.
Synairgen share price: trials and tribulations
The biotech company’s valuation was justified by its ongoing phase III trial into its novel ‘SNG001, a formulation for inhalation containing the broad-spectrum antiviral protein interferon beta.’
And unusually for biotechnology, the basic science behind the drug was easy to understand. Scientists found that covid-19 suppresses the natural production of interferon beta, which is part of the body’s natural defence against common diseases such as flu. Covid-19 suppresses the production of the compound, and Synairgen speculated that a direct dose into the airways through a nebuliser would trigger a stronger antiviral response in infected patients.
In phase II results, SNG001 cut the odds of a covid-19 patient in hospital developing severe disease by almost 80%. Patients were two to three times more likely to recover to ‘no limitation of activities’ post-disease. And it cut the average hospital stay by a third at a price of only £2,000, making it financially cost-effective for governments to mass-order.
The investment case was sound. Fellow biotech stock AstraZeneca is currently reaping the rewards of its successful phase III trial of Evusheld. The drug has been approved in the US as an antibody treatment for immunocompromised patients who cannot be vaccinated, after results demonstrated an 83% reduction at the median six-month analysis of developing symptomatic covid-19 compared to a placebo.
But breakthroughs are the exception rather than the rule; Synairgen investors have discovered this to their cost. The company has announced that ‘the international Phase 3 SPRINTER trial of SNG001 in patients hospitalised with COVID-19 did not meet its primary or key secondary efficacy endpoints.’ It further elaborated that ‘patients who received SNG001 were no more likely to be discharged from hospital than patients who received placebo, and patients who received SNG001 were also no more likely to recover to “no limitation of activities.”’
CEO Richard Marsden said the failure may have been due to the ‘standard of care which changed substantially between our Phase 2 and Phase 3 trials. This improvement in patient care may have compromised the potential of SNG001 to show a clinical benefit.’
However, there is a glimmer of hope for Synairgen. The trial threw up an ‘encouraging trend in prevention of progression to severe disease and death, which we strongly believe merits further investigation in a platform trial.’ And the company ‘eagerly’ awaits phase II data from a current trial on home-based covid-19 patients, which could still yield a positive result for SNG001.
But the collapsing Synairgen share price may be a harbinger for the biotech bubble. It's not the first biotech stock to collapse in recent months because of an underwhelming trial result. BridgeBio Pharma's share price collapsed in December when it made the ‘disappointing and baffling’ discovery that placebo patients with a rare heart disease could walk further after treatment than those given the company’s Alnylam drug.
Sensorion collapsed in January after its failed hearing loss medication trial. Rafael also fell hard after the inadequate performance of its lead cancer drug Devimistat in October. And Angion Biomedica has also suffered after the failure of both its covid-19 anti-fibrotic therapy and its ANG-3777 kidney transplant medication.
Of course, trial and error is fundamental to science. It’s far safer to invest in large-cap companies like AstraZeneca with the financial firepower to absorb research losses. But even the likes of Moderna and Pfizer are now far below their share price highs.
And many biotech companies are now struggling, with investors abandoning the sector as the pandemic falters and monetary policy tightens. According to Refinitiv, biotech firms in the US have raised $32.7 billion from launching Initial Public Offerings since the pandemic began. But 83% are now trading below their launch prices. Yet Synairgen still has a cash balance of £25 million. And better trial results could be forthcoming.
The UK was a biotech market leader in the early 2000s, but more than a third of UK biotech firms collapsed after the 2008 financial crisis. As inflation rises, a similar correction could be imminent.
* Best trading platform as awarded at the ADVFN International Financial Awards 2021


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Serrapeptase is the naturally occurring Chelation-Anti-Inflammatory Serrapeptase. This natural substance is the Proteolytic bioactive serra enzyme that was originally discovered in the intestine of the silkworm. The silkworms use this enzyme to dissolve proteins in their cocoons. Now it is commercial manufactured by fermentation, enabling mass production.
Serrapeptase can be used as a health supplement. As it digests protein it digests dead tissue, so as blood clots and cysts, reducing them to amino acids which are treated by our bodies as normal waste products. Because of this ability to digest protein, research has sown that the enzyme has anti-inflammatory pain relief possibilities. Serrapeptase has a wide clinical use, ranging from pain relief from sinusitis – breaking down nasal cavity mucus- to breaking down blood clots. Clinical studies have shown that this enzyme prevents swelling and fluid retention due to inducing a fibrinolytic, anti-inflammatory and anti-endemic activities.
Serrapeptase has a large clinical use in Europe and Asia, for over twenty five years, being used as a substitute for Ibuprofen and other non-steroidal anti-inflammatory drugs. As Serrapeptase is natural it is not a drug, simply a health supplement. Unlike the drugs Serrapeptase is used as a substitute for, this natural enzyme has no inhibitory effects on prostaglandins and has no gastrointestinal side effects.
Put simply, Serrapeptase is the second gift from silkworms to the human race. It has a wide range of clinical uses and no side effects. Serrapeptase is an anti-inflammatory and can be used instead of ibuprofen and other commercial anti-inflammatories.

domain: chemistry


When traveling on foot, pedestrians will experience very hot temperatures in summer months with accompanying dry conditions. Avoid walking in the heat of the day as extreme temperatures can cause heat-related illnesses for people and pets. Dallas can experience freezing rain in winter, although the temperature is not cold. Precipitation can freeze on contact with cement surfaces, making travel dangerous. Wait until icy surfaces melt before venturing out with your pet.
Residential properties in the area are large with trees and are well landscaped. Homes are well set back from street fronts with lots of space and privacy between residences. Most houses are bungalow style, although there are some two-story homes. A canal runs north to south through the east end and there is a sports stadium located adjacent to the canal in this area.
Vitruvian Park is located in the adjacent community to the north. The Farmers Branch, a widening of the waterway in the area, is situated in the park which has well manicured open lawns, shade trees, and paved pedestrian paths throughout the park and around the waterway. Vitruvian Park is a very picturesque green space and waterway to visit with your dog for a stroll or rest in the grass beneath a shady tree. In the past, trees in the park have been decked out with lights at Christmas, creating a magical light show on winter evenings.
Bachman Lake Park is located to the south of the Mill Creek Area. This 205-acre park has a 3-mile greenway for cyclists and pedestrians that is paved. Amenities in the park include picnic areas, water fountains, a boat launch, and an indoor pool. Love Field is located nearby and dog walkers in the park can also enjoy the excitement of aircraft taking off and landing.


text:
In 2012, exchange-traded products are ubiquitous in the world of investing. The more than 1,400 products have accumulated billions of dollars, and are widely used by all types of investors, from individuals with relatively small accounts and simple strategies to sophisticated hedge funds managing billions. So it may be hard to believe that the ETF industry is still relatively young; most ETFs have been around for only a handful of years, and it wasn't that long ago that assets were less than $500 billion. Below is a whirlwind history of the ETF industry, starting with the launch of the first exchange-traded product :
January 1993: S&P 500 SPDR (SPY) Debuts
When the first ETF began trading, Bill Clinton was in the Oval Office, gas cost about a dollar a gallon, and the Red Sox were still a decade away from ending their World Series drought. SPY launched with relatively little fanfare, but in the nearly 20 years since has accumulated more than $100 billion in assets.
April 1995: Second ETF Debuts
Just the second man to walk on the moon (Buzz Aldrin) is not nearly as well known as Neil Armstrong, the second ETF launched doesn't stick in the mind of many investors. In the spring of 2004, State Street rolled out its MidCap SPDR (MDY), which seeks to replicate the performance of the S&P MidCap 400 Index. MDY remains quite popular; this fund has about $10 billion in assets, and an average daily volume of about two million shares.
March 1996: iShares Debuts International ETFs
The first iShares ETFs to debut included a suite of international equity ETFs targeting Australia (EWA), Canada (EWC), Sweden (EWD), Hong Kong (EWH), Germany (EWG), Italy (EWI), Japan (EWJ), Belgium (EWK), Switzerland (EWL), Malaysia (EWM), the Netherlands (EWN), Austria (EWO), Spain (EWP), France (EWQ), Singapore (EWS), the United Kingdom (EWU), and Mexico (EWW).
December 1998: Sector SPDRs Debut
Today there are ETFs that deliver access to extremely narrow sub-sectors of the U.S. economy, including smartphones, platinum miners, and social media (SOCL). The first step on the road to this level of sector granularity was taken in late 1998, when a lineup of products targeting the major sectors of the U.S. economy debuted. The Sector SPDRs are pretty straightforward; they split up the S&P 500 by sector.
July 2002: Bond ETFs Debut
Bond ETFs have become tremendously popular in recent years, so it may be hard to believe that these products were born only a decade ago. iShares launched its first four bond ETFs IEF, LQD, SHY, and TLT in the summer of 2002.
LQD remains the largest bond ETF to this day, with about $24 billion in assets. TIP, which launched in December 2003, comes in second with about $23 billion.
November 2004: Gold SPDR (GLD) Launches
The first commodity ETF to debut was GLD, which offers exposure to physical gold bullion. Now the second largest ETF by assets, GLD didn't begin trading for more than a decade after the first ETF hit the market.
The second gold ETF, iShares IAU, debuted only a few months later in January 2005. In this case, the first mover advantage was significant. GLD currently has more than $70 billion in assets, while IAU has only $10 billion.
June 2006: ETNs Enter The Fray
In the middle of 2006 Barclays launched the first two exchange-traded notes: two products offering exposure to commodity futures contracts. The Dow Jones-UBS Commodity Index ETN (DJP) and S&P GSCI Total Return Index ETN (GSP) both offer access to diversified baskets of commodity futures contracts, though the mix between the two varies quite a bit.
During the past several years, ETNs have seen their ups and downs. But they are undoubtedly quite popular; as of June 2012 there were more than 200 ETNs with aggregate assets of more than $16 billion.
November 2009: Schwab Debuts Commission Free ETFs
Charles Schwab was a latecomer to the ETF game, but made a splash with the debut of four funds that could be traded commission free within Schwab accounts. In the months that followed, other brokerages quickly followed suit: Fidelity, TD Ameritrade, Vanguard, and E*TRADE all now offer commission free ETF trading.
December 2010: ETF Assets Hit $1 Trillion Mark
In late 2010 the ETF industry hit an inevitable milestone of $1 trillion. Thanks in large part to a stock market rally since bottoming out in early 2009, the the ETF total surpassed $1 trillion and never looked back. Assets have since climbed further, approaching $1.2 trillion and showing no signs of slowing down.
Disclosure: No positions at time of writing.
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domain: finance


text:
INDIA PREPARES TO SUBMIT CLIMATE TARGETS TO UN
Last week, India—the world’s third largest emitter of carbon dioxide—announced it is preparing to submit official plans to the United Nations with updated emissions targets in September (Straits Times). This obligation under the Paris Agreement was supposed to be fulfilled before last November’s UN Climate Change Conference (COP26). India previously threatened to withhold its climate commitment until rich nations provided more financial help to poor countries. The nation’s delay in submitting the document has also been attributed to inter-ministerial negotiations over its climate plan (Bloomberg).
During the COP26 conference last November, Prime Minister Narendra Modi announced that India would aim to achieve net-zero emissions by 2070—a target that has drawn criticism for being under-ambitious (Straits Times). In the short term, the nation plans to build sufficient infrastructure to attain 500 gigawatts of carbon-free electricity generation by 2030. While the country’s approach to climate action has drawn criticism abroad, India’s Environment Minister Bhupender Yadav has defended its record, saying India is one of the only nations that has met the targets it set out as part of the first nationally determined contribution in 2015 (Government of India). India’s submission is scheduled just weeks before the COP27 climate talks in Egypt in November, the focus of which will be on implementing existing emissions targets (Euronews).


|Publication number||US3544225 A|
|Publication date||Dec 1, 1970|
|Filing date||Dec 13, 1967|
|Priority date||Dec 13, 1967|
|Publication number||US 3544225 A, US 3544225A, US-A-3544225, US3544225 A, US3544225A|
|Inventors||Conde Hector O, Glaser Donald A, Wattenburg Willard H|
|Original Assignee||Berkeley Scient Lab Inc|
|Export Citation||BiBTeX, EndNote, RefMan|
|Patent Citations (5), Referenced by (14), Classifications (10)|
|External Links: USPTO, USPTO Assignment, Espacenet|
Dec. 1, 1970 w. H. WATTENBURG ETAL 3,544,225
PEAK READING OPTICAL DENSITY MEASURING SYSTEM Filed Dec. 13, 1967 S Sheets-Sheet 1 l3 l8 -AMPL|F|ER$ 4 f 1. PEAK DIGITAL TRANSDUCER 7 READER VOLTMETER \E I AMPLIFIER 1 l9 CONTROL PHOTOCELL/ (LIGHT SOURCE) 4 fi(LlGHTSOU;9CE) I 32 L, EEQQ Q ifs?) 23 (LIGHT SOURCE) INVENTORS WILLARD H. WATTENBURG DONALD A. GLASER BY HECTOR O. CONDE ,W,%.1;
F/Gj 4 I my R EYS Dec. 1, 1970 W. H. WATTENBURG ETA]- PEAK READING OPTICAL DENSITY MEASURING SYSTEM Filed Dec 13, 19s? 3 Sheets-Sheet 2 48 47 [49 R0. READ A 4 RC. GATE CAPACITOR,
' 69 FET GATE D 3/72 READ E I 7| RESET- F 7 64 DETECTOR. AMP
/ 56 57 5 I E i -DETECTOR 62\ GATE T 33 A fl F/G. ,6
32 INVENTORS C 33 WILLARD H. WATTENBURG BY DONALD A. GLASER 46 HECT R QCPyN DE G. 5 I
3,544,225 PEAK READING OPTICAL DENSITY MEASURING SYSTEM Willard H. Wattenburg, Orinda, Donald A. Glaser,
Berkeley, and Hector 0. Conde, San Pablo, Calif., assignors, by mesne assignments, to Berkeley Scientific Laboratories, Inc., Berkeley, Calif., a corporation of Texas Filed Dec. 13, 1967, Ser. No. 690,316 Int. Cl. G01n 21/06; G01j 1/44; G06m 7/00 US. Cl. 356201 6 Claims ABSTRACT OF THE DISCLOSURE An optical density measuring system for determining growth or reaction rates in materials disposed in a plurality of sample tubes sequentially and repeatedly presented to the optical system. The system includes means for commanding a peak reader which provides a signal representative of the peak density and means for indicating said density.
BACKGROUND OF THE INVENTION This invention relates generally to an optical density measuring system and more particularly to a system useful for determining growth or reaction rates of samples.
There are a number of applications where it is important to periodically measure the optical density of a sample. This information can give an indication of reaction time, growth rate, and other changes which are reflected by changes in optical density with time. One example is the study of growth of bacterial cultures in a nutrient or the effect of inhibitors on such growth. The study of the kinetic of enzymatic reactions is another example. Generally, the measurements are made by projecting a light beam, which may be monochromatic, through a sample holder such as a cuvette or test tube, receiving the transmitted light with a photoelectric transducer and indicating or registering the output from the transducer.
The measurement of growth of a single culture or sample is simple. A conventional test tube can be filled with the sample and placed in the light beam and readings taken periodically. Where it is only desired to obtain the growth rate, an absolute reading is not required. A conventional test tube can be employed as long as it remains in one position.
However, it is desirable to be able to measure the changes in optical density of a plurality of samples with a single optical measuring apparatus. Prior art apparatus includes means for disposing a plurality of sample holders in racks and means are associated with the racks for moving the same to sequentially present the sample holder in each of the racks to an optical measuring system. It is, however, diflicult to accurately position or locate the racks and, therefore, the optical path may change from one reading to the next. To overcome this difliculty, cuvettes having parallel flat faces have been employed. This, of course, makes the sample holders relatively expensive.
Many alternatives have been used top rovide absolute measurements using this system. Matched test tubes, as mentioned, is one. Alternatively all test tubes, whose identification is provided, can be first calibrated by filling them with the same known substance. This first reading can be remembered, the test tubes emptied, washed, dried and the unknown substance poured into them. The answer to the next reading, multiplied by a factor proportional to the first reading, is the optical density of the unknown. Of course, during the operation, the test tubes United States Patent should not be rotated, as light irregularities in concentricity induce large errors in the readings, the test tubes being part of the optical system.
SUMMARY OF THE INVENTION AND OBJECTS Generally, the present invention relates to a system which, like in the former apparatus, includes a reading station having a light beam and a photoelectric transducer spaced therefrom to receive the light transmitted by the sample and bolder and develop an electrical light. The system also includes means for sequentially and repeatedly presenting samples to the reading station. The system of the present invention allows the sample to move continuously through the light beam. Means are included to generate a signal which instructs the circuits to read the light transmitted at a particular time. The output from the photoelectric transducer is then read and a output signal representative of the peak amplitude is generated. This signal is received, processed and indicated. Means are provided for conditioning the signal receiving circuit to receive the signal from the next sample tube following indication.
It is a general object of the present invention to provide an improved system of the above type which does not require expensive sample holders.
It is another object of the present invention to provide a system of the above character which is simple in construction.
It is another object of the present invention to provide a system in which thefocusing characteristics of the test tubes are employed to provide a maximum signal to the circuits which serve to store and provide an indication of the peak amplitude.
It is another object of the present invention to provide a system for analyzing growth and reaction kinetics of selected samples.
The foregoing and other objects of the invention will become more clearly apparent from the following description when taken in connection with the accompanying drawing.
BRIEF DESCRIPTION OF THE DRAWING FIG. 1 is a block diagram of a system in accordance with the invention.
FIG. 2 is a perspective view of a test tube rack carrying test tubes.
FIG. 3 schematically shows the test tube rack associated with a reading station.
FIG. 4 is a view taken along the line 44 of FIG. 3.
FIG. 5 shows the light beam and focusing characteristics of the test tube.
FIG. 6 is a more detailed block diagram of the system of the present invention.
FIG. 7 is a detailed schematic diagram of the peak reading system of the present invention.
FIG. 8 shows the waveforms at various points in the circuit of FIG. 7.
DESCRIPTION OF THE PREFERRED EMBODIMENT Referring to the block diagram of FIG. 1, a photoelectric transducer 11 is adapted to receive the light transmitted by the sample holder. The output of the transducer is applied to amplifier 12. The output of the amplifier is applied to a peak reader 13. In addition to the signal representative of the transmission, a control signal is applied to the peak detector. This signal is derived from a photocell 16 which has its output applied to an amplifier and control circuit 17, and thence to a peak reader 13.
This signal controls the peak reader whereby it is active during a short period of time at or near the peak signal from transducer 11. The output from thepeak reader may be applied to a digital voltmeter 18 to provide an indication of the amplitude. The digital voltmeter provides a feedback signal 19 to the peak reader to reset the peak reader and ready it for the next sample holder presented to the photocell. v Referring particularly to FIG. 2, a tube holder or rack 21 includes a plurality of wells 22'adapted to receive sample holders or tubes 23. The sample holders are vertically disposed in the rack 21. An opening 24 is provided near the bottom of the holder to expose the lower portion 26 of the holders. In the present example,.a plurality of locating holes 27 are provided in the holder. As will be presently described, the locating holes serve to provide an output pulse to the amplifier and control circuit 17 to activate the peak reading circuit so that it reads the density as each opening 24 is presented to the optical reading system. Referring particularly to FIG. 3, the holder 21 including sample holders-23 is indicated as travelling in the direction as shown generally by the arrow 29. As the holder travels, it serves to sequentially present sample holders 23 to the optical reading system. For example, the optical reading system may comprise a light source 31 which projects a beam 32 towards a phototransducer 33. As the openings 24 are placed in the light beam, light is transmitted through the holder and sample to the transducer which develops an output electrical signal.
There is also provided a second light source. 36, FIG. 4, which projects a beam 37 adapted to impinge on the rack so that it projects through the locating holes 27 as a rack is moved past the reading station. When an opening 27 is in line with the beam 37, light is transmitted to a photocell 38 which generates an output pulse which is applied to the amplifier and control circuit 17. The output pulse accurately indicates the location or position of the holder.
As described, the rack is moved past the read station. The present apparatus includes a feeding mechanism which moves a plurality. of racks each containing sample holders in an endless loop past the optical reading system. A suitable mechanism for moving and presenting test tubes in the manner described might, for example, be
an LKB 7000A Ultro-Rack Fraction Collector, suitably modified for that. purpose.
Referring now to FIG. 5, the beam 32 is shown for three positions of a sample holder. In the first position, the beam is shown as it passes through the holder as it is first presented thereto. It is noted that the walls of the holder deflect the beam as shown at 43 and that it does not impinge upon the transducer 33..When the tube is in its center position, the beam strikes substantially parallel walls and is then projected as shown at 44 onto the transducer 33. As the test tube continues to advance, the beam strikes the other curved portion of the test tube and is deflected as shown at 46. Thus, there will be a peak output from the transducer 33 when the holder is centered.
The output of the photocell 33 is shown in FIG. 8A. The first peak 47 represents stray light which impinges upon the transducer as the opening 24 advances through the beam. Thereafter, the light is deflected from the transducer by the sample holder and there is no output until the beam is focused to strike the transducer and produce an output peak 48. As the rack continues to advance, a third output 49 is obtained which is the stray light between the other side of the sample holder and the opening 24.
The pulse generated by the transducer 38 is shown in FIG. 88. It is seen that the pulse begins before the output from the photocell 33 occurs and ends shortly thereafter.
A detailed block diagram is shown in FIG. 6. The output of transducer 33 is applied to three stages of amplification represented by the amplifiers 56, 57 and 58. The amplifier 58 serves as an isolation amplifier and its output applies current to a precision capacitor 61.
The capacitor is shorted out by gate 62 at all times except during the reading period. The gate 62 is opened by the pulse 51 from the transducer 38. Thus, when a pulse is present, the gate 62 is opened thereby allowing the capacitor 61 to charge. The capacitor will charge to a value which corresponds to the peak value of the output of the transducer 33 indicated at 48, FIG. 8A. An amplifier 63 is connected to the precision capacitor and provides an output signal on the line 64. This signal will be indicative of the peak signal. The gate 62 is closed by the feedback signal applied from line 19. This discharges the capacitor after the output 64 is read thereby allowing reading of the next pulse. FIG. 8C shows the voltage on capacitor 61. Thus, the capacitor charges following input pulse 48 along the line 66 to a peak value as represented by 67. As soon as the peak value is read by the analog to digital converter, the capacitor is discharged as shown at '68. Operation of the gate 62 is shown in FIG. 8'D. Thus, the gate is opened with the beginning of the pulse 69 and is closed with the termination of the pulse. The reset pulse on line 19 is shown at 71, FIG. SF. The read pulse which serves to command associated apparatus to read the voltage 67 on the capacitor is shown at FIG. SE. A detailed circuit diagram of a peak reading circuit corresponding to the block diagrams of FIGS. 1 and 6 is shown in FIG. 7. In the present circuit extensive use is made of integrated circuit amplifiers. The amplifiers are Models 709C manufactured by Fairchild Semiconductor Corp., Mountain View, Calif. Photodiode 81 provides a signal to the input of the first gain of one amplifier stage 82. The output from this amplifier is applied to a second amplifier 83 which includes both a zero adjustment 84 and a gain adjustment 85. The amplified output is applied to an isolation amplifier 87 which feeds a current to the precision capacitor 61. When the capacitor is fully charged and there is no more change in voltage, the circuit 86 including the transistor 2N3704 and associated circuitry generates a command pulse which commands the read circuits to read the voltage on the capacitor. The voltage on the capacitor is available on line 88 connected to the capacitor through isolation amplifier 89.
p The field effect transistor 3N124 acts as the gate. and is closed to essentially short out the capacitor 61 between reading cycles. The field effect transistor is controlled as follows: when light is received by the photo-transistor 91, a pulse is applied to a Schmitt trigger 92 which triggers if the voltage exceeds a predetermined value. The Schmitt trigger then controls a bistable circuit 93 which provides an output pulse 72, FIG. SE, to amplifier 94 which drives the field effect transistor. A reset pulse is applied to the bistable circuit 93 along the line 19 as previously described. If desired, the bistable circuit may be replaced by a monostable circuit which has a predetermined switching time whereby when a pulse is received from the Schmitt trigger, the monostable circuit switches to open the field effect transistor for a predetermined period of time to allow the capacitor to charge and the peak voltage to be read, at which time it switches to close the field effect transistor and short the capacitor.
The read pulse occurs only when light strikes transducer 91 whereby to eliminate any interference from noise, stray light or the like. Thus, the peak reading is obtained and the transducer only reads as the tube is directly in line. Since the maximum is always read as the particular test tube circulates through the apparatus and is represented for its second reading. Any variation will be due to change in density.
A system including a circuit with the component values shown was constructed and operated. Repeatability be tween successive readings of a reference sample tube was within 1.5 percent.
Thus, there is provided an improved optical density measuring system in which standard sample holders such as test tubes may be employed. The comparative readings indicating changes in optical density will be relatively accurate since the readings are taken at the same location on the tube when a peak reading occurs. In order to increase the accuracy of the readings, matched test tubes can 'be used.
1. In a system of the type described in which an optical reading station, comprising means forming a lightbeam and a photoelectric transducer spaced therefrom v to receive said beam and provide an electrical signal proportional to the light intensity, has presented thereto sequentially and repeatedly samples for analysis, the improvement comprising means for continuously moving the samples through said reading station, a signal processing system including means serving to generate a read signal for each sample, means serving to receive the signal from the photoelectric transducer responsive to said read'isignal and provide a peak signal representative of the peak amplitude of said phototransducer signal as the samples are moved therethrough, indicating means for receiving said peak signal and providing an indication of the same and conditioning" means for conditioning said means f or receiving said signal to receive an input signal corresponding to the next sample. n
2. A system as in claim 1 wherein said means for providing a peak signal comprises a capacitor adapted to be charged to a peak value by the signal from said transducer.
3. A system as in claim 2 in which said conditioning means includes a gate means having an open and closed condition connected to said capacitor and serving to short out the capacitor in its closed condition, said gate being changed to its open condition in response to said read signal to allow the capacitor to fully charge and being closed after the peak signal is indicated.
4. A system as in claim 1 in which the samples for analysis are disposed in sample holders carried by holding means include an aperture whereby said light beam cooperates with the holding means to impinge on the transducer only when the sample holder is centered in the beam.
5. A system as in claim 1 wherein said means for generating a read signal includes a second photoelectric transducer.
6. A system as .in claim 1 wherein said means for receiving the peak signal and providing an indication of the same comparises a digital voltmeter.
References Cited UNITED STATES PATENTS 2,809,751 10/1957 Hall 256-223 X 3,057,254 10/ 19,62 Drury 356226 X 3,245,533 4/ Rottmann 250223 X 3,322,958 5/ 19:67 Heiss 250223 X 3,415,997 12/ Vinzelberg et al. 250-218 X WILLIAM F. LIhiDQUIST, Primary Examiner T. N. GRIGSBY, Asistant Examiner U.S. c1. X.R.
2so 21s, 223; 35639, 226, 227
|Cited Patent||Filing date||Publication date||Applicant||Title|
|US2809751 *||Nov 2, 1954||Oct 15, 1957||Stokes F J Corp||Tablet grading means|
|US3057254 *||Oct 12, 1960||Oct 9, 1962||Honeywell Regulator Co||Photographic light meter|
|US3245533 *||Dec 19, 1963||Apr 12, 1966||Owens Illinois Glass Co||Inspecting glass container for horizontal checks|
|US3322958 *||May 7, 1964||May 30, 1967||American Instr Company Inc||Photometer automatic sample changer|
|US3415997 *||May 28, 1965||Dec 10, 1968||Bayer Ag||Radiation sensitive ampoule testing apparatus and method|
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US3704950 *||Feb 22, 1971||Dec 5, 1972||Sargent Welch Scientific Co||Electrical system for use in optical densitometry|
|US3804535 *||Oct 13, 1972||Apr 16, 1974||Baxter Laboratories Inc||Dual wavelength photometer response circuit|
|US3847486 *||Jun 7, 1972||Nov 12, 1974||Mccabe W||Automated spectrophotometer apparatus and computer system for simulataneous measurement of a plurality of kinetic reactions|
|US3882318 *||Jan 21, 1974||May 6, 1975||Hycel Inc||Detector means for an automatic chemical testing apparatus|
|US3932763 *||Jul 29, 1974||Jan 13, 1976||Sensor Technology, Inc.||Detector for tubular transparent article|
|US4501491 *||Mar 10, 1982||Feb 26, 1985||Salus Ricerca E Sviluppo Di Croce' Dr. Francesco & C. Snc||Device for optical indication of the phenomena of coagulation of blood, concentration and aggregation of blood platelets, or the like|
|US4729661 *||Jul 29, 1985||Mar 8, 1988||Specialty Medical Industries, Inc.||Asynchronous serial cuvette reader|
|US4970165 *||Sep 5, 1989||Nov 13, 1990||Montefiore Hospital Association Of Western Pennsylvania||Cell harvester tray|
|US5059025 *||Mar 29, 1990||Oct 22, 1991||Shimadzu Corporation||Spectrophotometer|
|US5952218 *||Apr 2, 1998||Sep 14, 1999||Akzo Nobel, N.V.||Container holder reflectance flag|
|US6388751 *||Sep 11, 1997||May 14, 2002||John Ernest Foster Holley||Apparatus for determining optical properties of liquid samples|
|DE4117008A1 *||May 24, 1991||Nov 28, 1991||Suzuki Motor Co||Messvorrichtung zum erfassen eines aggregationsbildes|
|EP0049561A1 *||Aug 6, 1981||Apr 14, 1982||Coulter Electronics, Limited||Method and apparatus for repeated monitoring of optical absorption by a plurality of specimens|
|WO1999051718A1 *||Mar 22, 1999||Oct 14, 1999||Akzo Nobel N.V.||Container holder reflectance flag|
|U.S. Classification||356/440, 250/565, 250/223.00B, 356/226, 356/227, 356/39|
|International Classification||G01N21/25, G01N21/27|