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Skin rashes are characterized by red and ichiy skin, often accompanied by small bumps and other changes on skin color, appearence or texture They may occur on any part of the body or be widely distributed on large portions of skin.
This minor yet irritating problem is frequently caused by issues like eczema, psoriasis, allergies, insect bites, mites, acne, excessive sweating, or contact with certain poisonous plants like poison ivy or oak. Soaps, detergents, shampoos or cosmetics that do not suit your skin can also lead to rashes this looks bad on your face and steal your beauty it can be cause dby these problems which you have been read above.
Rashes may be a symptom of certain fungal, bacterial, or viral infections as well. If you have a rash that does not improve or go away within a few days, you should consult to the doctor as soon as possible.
HOME REMEDIES FOR RED RASHES
Here we are giving you some remedies for red rashes on your face or body it will help you to get rid of from this disease.
Extra-virgin olive oil works as a moisturizer, facilitates healing and promotes skin renewal as it is rich in vitamin E and antioxidants. It will also soothe your skin and reduce itching or irritation.
For this you need simply rub extra-virgin olive oil or a combination of equal parts of olive oil and honey on your rash a few times daily until it heals completely.
Alternatively, you can add a little turmeric powder o some olive oil and apply it two or three times a day for a few days. But beware if turmeric powder does not suits you then don;t use it, Packed with antibacterial and anti-inflammatory properties, turmeric soothes rashes and relieves itching.
In addition to olive oil, castor oil and coconut oil help heal rashes naturally. A combination of vitamin E oil and cod liver oil is another popular remedy you can also use these oils to get rid of from these problems.
2. Baking Soda
In every kitchen you wilol find baking soda baking soda also helps you to clear your skin and also give syou fair complexion. Baking soda helps dry out skin rashes. Plus, it relieves the itching and inflammation associated with rashes For this remedy you need to do this.
Add one part baking soda to three parts water. Apply the mixture on the affected area. Leave it on for a few minutes before rinsing it off. Do this once daily for a few days.
The secon remedy for this is you can also mix baking soda with some coconut oil to make a paste and apply it on your rash. Leave it on for about five minutes and then rinse it off. Repeat this once or twice daily until you see improvement.
Note: Do not leave baking soda on your skin for too long because it may cause further irritation and can cause problem to your skin.
Oatmeal is great for alleviating skin irritation and inflammation due to its soothing and anti-inflammatory properties. It is excellent for rashes cause by poison ivy, eczema, sunburn, chicken pox and allergies oatmeal is also good for our health too.
Grind oatmeal in a blender, food processor or coffee grinder. Mix one cup of finely ground oatmeal in warm bath water. Soak in it for at least 15 or 20 minutes. Do this daily until the rash is gone.
Alternatively, combine one-half cup of oatmeal, one-quarter cup of milk powder and two teaspoons of honey. Put this mixture in a muslin cloth, tie it strongly with a string, ribbon or rubber band, and place it in a bath tub filled with warm water. Soak in the milky bath water for at least 15 minutes. Finally pat dry and moisturize your skin. Repeat this remedy daily for a few days.
For rashes on your face, apply a thick paste of equal amounts of oatmeal and plain yogurt mixed with a little honey. Leave it on for about half an hour before washing it off. Do this daily until you see improvement.
4. Aloe Vera
Aloe vera is best for your skin and also resoves all your problem related to skin, Due to its anti-inflammatory, emollient, antibacterial and antifungal properties, aloe vera is excellent for treating a number of skin ailments including rashes. Apart from healing, it also soothes the skin, relieves itching and reduces redness.
Extract fresh aloe vera gel from an aloe leaf. Apply it on the affected area. Leave it on for at least 20 minutes, and then rinse it off. Do this at least three times a day until the rash clears by this remedy your rashes will clear out for sure.
If you do not have fresh aloe vera gel, you can buy aloe vera gel or extract.
5. Cold Compress
A cold compress can be beneficial in reducing rashes, especially those caused by heat, insect bites, poison ivy and shingles. It helps ease itching, swelling and inflammation, and can be particularly useful if a rash begins to develop into blisters.
put ice cubes in a sealed plastic bag and place it on the affected area for a few minutes. Repeat a few times daily for a few days.
Alternatively, you can simply soak a clean washcloth in ice-cold water and place it on the rash for about 10 minutes.
Note: Do not put ice cubes directly on the skin otherwise it will increase your problem.
6. Apple Cider Vinegar:
Raw and organic apple cider vinegar is another excellent home remedy to treat skin rashes and calm the itching. Moreover, its acetic acid content helps fight skin infections that could be causing or aggravating the problem apple cider vineger also good for your hair too.
you need to do this to apply these remedy.
Dip a cotton ball in apple cider vinegar and place it on the affected area.
Leave it on for a few minutes, and then remove the cotton ball.
Do this several times a day for a few days or until your rash clears.
Note: If apple cider vinegar causes irritation, try diluting it with water before applying it. If the irritation persists, then try another remedy and if you willsee allergic reaction rinse away it soon.
web-title: home remedies for skin red rashes
keywords: skin, rashes, itching, spots, home, remedies


The massive trend in new energy vehicles in China and around the world is one reason for BMTS’ success. We provide products to improve the efficiency of powertrains and thereby contribute to a better environment. Our products are specifically developed for the latest high efficiency power trains like Dedicated Hybrid and Range Extended vehicles. Our turbochargers, electrical turbochargers and electric compressors enable our customers to reach the highest efficiencies. This is a major contributor to a sustainable future. The proven reliability, quality and performance of our products is part of this goal, as only a reliable product is supporting sustainability.


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Megan Fox shows off post-pregnancy return to form on Beverly Hills red carpet
New York Daily News
Actress Megan Fox transformed a charity event into an event Friday afternoon showing off her stunning body for her first red carpet after giving birth in September.
Highly Cited:Megan Fox - Megan Fox had to get a nanny
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Jennifer Lawrence's Golden Globes Meryl Streep
Star Jones whose rapid weight loss led to exit from "The View" in 2006 denies gastric bypass surgery on Oprah Winfrey Show
Former Playboy cover girl Jenny McCarthy had a few words for an outspoken film critic
Brandi Glanville Walks First Oscars Red Carpet in Crazy Cleavage-Baring Dress
Student Suspended Over ‘Hot For Teacher’ Essay, Files Lawsuit #funny
Maria Kirilenko, tennis
Misty May-Treanor- Two time olympic gold medalist
Bieber and Gomez split; Justin dating Victoria's Secret model Barbara Palvin?
Anne Hathaway In 'Taming Of The Shrew'? Oscar Nominee Could Star In Shakespeare Update


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That is the view of Sinn Féin Chief Negotiator Martin McGuinness who expressed disappointment over Ian Paisley's attack on party president Gerry Adams and accused the DUP leader of compounding the negative leadership of recent months and being in denial about his responsibility to get the peace process back on track.
"Last weekend's violence is a response to the realisation that the status quo is not an option and to the uncertainties of a process of change which demands equality, human rights, proper policing, justice and inclusion. It is a response to the dawning reality that the days of domination, triumphalism and second class citizenships are gone forever"
Martin has also called on Unionism to sit down with Republicans in an effort to move the process forward.
There can be no future for this country unless we learn to live together. This can not happen while Unionism deludes itself that somehow Equality = Concessions

domain: news


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Individual Counselling & Psychotherapy in Hamilton, Ontario
Do you want to have more satisfaction in your life? Do you want to explore at a deeper level what triggers you and makes you react in your home, work, and the community? If you have an area in your life where you feel stuck, frustrated, or hopeless, it often stems from old wounds. Compassionate exploration can free you from old patterns and move you towards what you truly want in life.
I won’t tell you to think positive or look on the bright side to shift your mood. Those strategies will help to some degree, but they won’t offer healing. These types of strategies often lead to shame and resentment in those moments when you just can’t muster the strength to choose a new pattern. Together we will explore the wisdom in old patterns of thoughts & behaviours and explore the blocks or problems that you yearn to change to in your life. We will work together to make the shifts you are craving to make in your life.
I work with people with diagnosed mental health issues such as anxiety & depression, and I also work with individuals who don’t have any diagnosis. Often individuals without a diagnosis minimize their problems because it always seems like others have it harder than you, so you don’t want to complain. Everyone struggles at times and needs support during different periods of their life. You have a right to voice your needs.
Adults & Teens
I work with both adults and teenagers. I have spent a good portion of my career working with both adults and teenagers. I have worked for many years in the field of child and youth mental health.
Frequency of Appointments
There are no rules about frequency and number of sessions for my clients. Everyone has different needs. Many clients start by having weekly sessions and then lengthen the time between sessions to bi-weekly, monthly, or as-needed. Some clients like to have 1.5 hour sessions less frequently. Other clients like to have a few months of weekly sessions with an end-date in mind. I can give you recommendations based on your needs.
Ready to Book an Appointment?
2SLGBTQ+ friendly spaces.

domain: health


Transdermal Gasotransmitter Sensor (TAGS™)
TAGS is designed as a non-invasive point-of-care diagnostic technique for detection of endothelial dysfunction in the high risk diabetic population. It is based on a state-of-the-art sensing technique to detect the presence of and measure the concentration of biomarker of endothelial dysfunction, hydrogen sulfide . Inspired by the office-based  system, the miniature home-based technology is currently under development at Exhalix.
When attached to the skin, TAGS can discriminate the condition of high concentration (healthy microvascular blood perfusion, BOTTOM) from low concentration (abnormally low perfusion, TOP).


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Andie MacDowell (age: 59) is an actress known for Sex, Lies, and Videotape, Groundhog Day, Four Weddings and a Funeral, St. Elmo's Fire, Short Cuts and Multiplicity.
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Andie MacDowell bio
Andie MacDowell (born April 21, 1958 as Rosalie Anderson MacDowell) is an American Actress and fashion Model. She made her film debut in 1984’s Greystoke: The Legend of Tarzan, Lord of the Apes, before receiving critical acclaim for her role in Sex, Lies, and Videotape (1989). Since then she has appeared in several notable films, including Groundhog Day (1993) and Four Weddings and a Funeral (1994). She has also starred in Green Card (1990), Short Cuts (1993), Michael (1996) and Multiplicity (1996).
In the early 1980s, MacDowell modelled for Vogue magazine and appeared in ad campaigns for Yves Saint Laurent, Vassarette, Armani perfume, Sabeth-Row, Mink International, Anne Klein and Bill Blass. A series of billboards in Times Square and national television commercials for Calvin Klein drew attention to her and led to her 1984 film debut in Greystoke: The Legend of Tarzan, Lord of the Apes, a role in which her lines were dubbed by Glenn Close because her Southern accent was too pronounced for her to play the role of an Englishwoman. In 1985, she had a small part in St. Elmo’s Fire. MacDowell studied method acting with teachers from the Actors Studio, in addition to working privately with the renowned coach Harold Guskin. Four years later, director Steven Soderbergh cast her in the independent film Sex, Lies, and Videotape (1989). Her performance earned her an Independent Spirit Award, a Los Angeles Film Critics Association Award for Best Actress, several other award nominations and led to a series of starring roles in films such as Green Card, The Object of Beauty, and Short Cuts. In the 1990s, MacDowell achieved stardom due to the box office success of director Harold Ramis’s 1993 comedy, Groundhog Day, and Four Weddings and a Funeral (1994), opposite Hugh Grant
Since 1986, MacDowell has appeared in print and television advertisements for the cosmetic and haircare company L’Oréal. In later years she has acted primarily on television and in independent films. In 2012 she co-starred in the short-lived ABC Family series Jane by Design. Since 2013, she has starred in the Hallmark Channel family series Cedar Cove.
[https://twitter.com/andiemacdowell3], [https://www.facebook.com/therealandiemacdowell], [https://en.wikipedia.org/wiki/Andie_MacDowell], [http://www.imdb.com/name/nm0000510/]
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domain: celebrity


Nov. 30 (UPI) — President-elect Joe Biden on Sunday announced an all-female White House senior communications team.
On Sunday evening, Biden’s transition team issued a statement declaring the team the “first senior White House communications team comprised entirely of women.”
“These qualified, experienced communicators bring diverse perspectives to their work and a shared commitment to building this country back better,” said Biden.
Former President Barack Obama’s White House communications director, Jen Psaki, will serve as White House press secretary, Biden announced.
Additionally, Kate Bedingfield, who served as deputy campaign manager and communications director for Biden’s campaign, will be the new White House communications director, and Pili Tobar, Biden’s communications director for coalitions, will serve as deputy White House communications director.
Karine Jean Pierre, senior Biden campaign adviser and chief of staff to Vice President-elect Kamala Harris, will serve as principal deputy press secretary.
Symone Sanders and Ashley Etienne — both senior advisers on Biden’s campaign — will serve as chief spokesperson for the vice president and communications director for the vice president respectively.
The role of communications director for first lady Jill Biden will be filled by Elizabeth E. Alexander, another Biden campaign senior adviser.
The announcement comes after Biden has made selections for several cabinet positions including Janet Yellen, who would become the first woman to serve as treasury secretary.


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"But it's what we do with our marriages all the time.To me it's a very simple mathematics equation: the more energy that goes (outside the marriage), the less energy goes into your marriage."Remain optimistic. If both parties are willing to work on their issues, anything is fixable.The experts shared tips for coping with a cyber affair or flirtation, whether you're the culprit or the victim — and obviously, this advice has relevance for anyone dealing with infidelity of any kind: For the victim: Have compassion for yourself, said relationship expert Stacey Martino (loveandpassioncoach.com)."They're going to be in shock and betrayal, and faced with the fear of having their life turned inside out, wondering how they're going to survive without their partner if things don't get resolved."What's needed is a neutral party to explain that this type of relationship is hurtful and harmful."For the cheater: Understand the trauma."Finding out your spouse has cheated is traumatic, and trauma kind of lingers," Rosenberg said.' They might not be able to cross that bridge of forgiveness with you."Forgiveness isn't easy.
She is an author and she'd just been called a pagan and a Wiccan by a reader who didn't find her writings on Christianity to be Christian enough."People underestimate that trauma because no one talks about it. You have to understand what the person went through and give them the opportunity to let it go.So that needs to be addressed, preferably with a therapist." For the victim: Don't hang on to the blame game.Smith in an article for the American Psychological Association, "Are Internet Affairs Different?" The freedom to fantasize, without the intrusion of reality — as well as the anonymity afforded by the Internet — also can be alluring.

domain: psychology


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Even if you have two left feet it’s possible to train for the gorgeous, toned legs of a dancer that everyone envies.
The secret? Do regular cardio to burn off fat, stretch daily to create length and fluidity — and sculpt with targeted moves to reshape the muscles of the hips, thighs and glutes.
You Might Also Like: Exhale Core Fusion Boot Camp
We’ve plucked 4 signature moves from the typical dancer’s routine to help you transform your lower body. Do this routine 2-4 times a week and you should begin seeing results in about 30 days
Here’s the deal: Do 1-3 sets of each exercise, 8-15 reps per set. Focus on form, especially staying tall and being precise in your body placement. Use AcaciaTV‘s Liz LeFrois –pictured demonstrating the moves below –as your guide.
Elegant Side Lift
[A] Stand with your feet hip-width apart, arms gracefully held up at shoulder-height. Square your hips, shift most of your weight onto your left foot and extend your right foot straight out to the side, toes pointed. [B] Lift your right foot up and out to the side a few inches. You should feel your standing left leg work to balance as well as a strong pull through your right hip. Complete reps and repeat to the other side.
[A] Stand tall with your feet wider than hip-width apart, toes turned out. Gracefully hold your arms up at chest height in front of you. [B] Bend your knees until your thighs are parallel to the floor. [C] Stand back up to the start taking care to keep your knees soft.
[A] Stand tall with your feet hip-width apart. [B] Bend your knees as you extend your arms up overhead, focusing on making your torso long. torso. [C] Stand back up to the start taking care to keep your knees soft.
[A] Stand tall with your feet hip-width apart, your arms held gracefully up at shoulder height. [B] Step your right foot back and to the side of your left foot as you bend both knees. [C] Once your left leg is parallel to the floor and your right knee is hovering above it, stand back up to the start. Complete all reps and repeat to the other side.
Now that you’ve got that “tendu” attitude, learn more about creating a dancer’s body by signing up for an AcaciaTV 10 Day trial. We’ve got hours of dance-inspired workouts you can stream anytime, anywhere from any device, including an exclusive Dancer’s Body Workout starring LeFrois.


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Articles on Sept. 10 and Sept. 16 incorrectly reported that amendments approved by the House and by the Senate Appropriations Committee would block implementation of the adminstration's new overtime pay rules. The amendments apply to a portion of the new rules but would let stand a provision that raises from $8,060 to $23,660 the annual wage level at which a worker is automatically eligible for overtime. (Published 9/18/04)
The Senate Appropriations Committee voted yesterday to block the Bush administration's controversial new overtime pay rules, but only after the Senate's most senior Republican warned that a slew of such legislative riders could complicate final deals on bills needed to fund the federal government in fiscal 2005.
The provision, approved 16 to 13, was attached to a $142 billion bill funding the Labor, Education, and Health and Human Services departments next year. The House attached a similar provision to its version of the bill last week, defying a threat by the White House to veto the entire bill unless Congress gives way on the issue.
Under the administration's three-week-old overtime regulations, individuals earning up to $23,600 a year would automatically be eligible for overtime pay, compared with the previous threshold of $8,060. But pro-labor lawmakers charge that the rules would allow employers to forgo overtime pay for thousands of higher-paid workers.
Although annual appropriations bills are always vehicles for riders that stand little chance of passing on their own, the practice is a source of frustration this year to Sen. Ted Stevens (R-Alaska), the Senate's longest-serving Republican and the chairman of the Appropriations Committee.
Stevens, who has vowed to send the 2005 spending bills to the president before his term as chairman expires at the end of the year, sees the flurry of legislative provisions as a potential obstacle to that goal.
"We should stick to our work," he shouted at one point yesterday, when Sen. Patty Murray (D-Wash.) pressed for legislative language on the education, labor and health bill that would end large federal subsidies to banks making loans to students.
She withdrew the amendment only after Stevens promised to incorporate in the bill language to resolve the problem before the measure goes to the floor.
The issue is one of many that could complicate final agreement between Congress and the White House on 11 spending bills.
In a bipartisan vote, the House approved a provision preventing the Internal Revenue Service from hiring private contractors to collect taxes. It was attached to an $89 billion bill paying for Treasury and Transportation department programs and operations in 2005.
When debate resumes on that bill next week, it could become the vehicle for an even more far-reaching rider backed by some Washington area lawmakers -- a measure drastically revising the administration's rules allowing private contractors to bid for jobs now performed by government workers. The White House has threatened to veto the bill if it contains that language.
Other pending bills contain riders easing trade restrictions on Cuba and limiting a section of the USA Patriot Act that permits searches of library records.
On Tuesday, House members passed up a chance to deny themselves their annual automatic pay raise of about $4,000, when they defeated a procedural move that could have opened the issue for debate.
Meanwhile, major spending issues remain to be worked out. The Senate committee's version of the 2005 foreign aid spending bill, approved yesterday, would provide less than the administration sought for its signature Millennium Challenge Corp., though funding would be increased by $120 million over this year. Funding for HIV/AIDS programs would fall short of the authorized level, and the committee voted to reduce the money for the Export-Import Bank and the economic support fund.
The AIDS and Millennium Challenge funds are part of the $19.5 billion foreign aid bill.
The House has approved a similar reduction for the Millennium Challenge, as lawmakers have shown little hesitation in shifting money from that Bush priority to their own.


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Perficient, Inc. (NASDAQ:PRFT) saw a significant growth in short interest in the month of October. As of October 31st, there was short interest totalling 2,390,000 shares, a growth of 7.7% from the September 30th total of 2,220,000 shares. Currently, 7.6% of the company’s shares are sold short. Based on an average daily volume of 296,000 shares, the short-interest ratio is presently 8.1 days.
Several institutional investors have recently added to or reduced their stakes in the company. Lisanti Capital Growth LLC purchased a new stake in shares of Perficient in the 3rd quarter valued at approximately $5,409,000. Boston Advisors LLC raised its stake in shares of Perficient by 32.5% in the 3rd quarter. Boston Advisors LLC now owns 45,359 shares of the digital transformation consultancy’s stock valued at $1,750,000 after acquiring an additional 11,134 shares during the period. Mackay Shields LLC raised its stake in shares of Perficient by 7.8% in the 3rd quarter. Mackay Shields LLC now owns 87,261 shares of the digital transformation consultancy’s stock valued at $3,366,000 after acquiring an additional 6,300 shares during the period. Emerald Mutual Fund Advisers Trust purchased a new stake in shares of Perficient in the 3rd quarter valued at approximately $5,088,000. Finally, Emerald Advisers LLC purchased a new stake in shares of Perficient in the 3rd quarter valued at approximately $4,728,000. 90.12% of the stock is currently owned by institutional investors and hedge funds.
PRFT has been the topic of a number of analyst reports. ValuEngine downgraded shares of Perficient from a “buy” rating to a “hold” rating in a research note on Wednesday, October 2nd. William Blair initiated coverage on shares of Perficient in a research note on Monday, September 9th. They set an “outperform” rating on the stock. Barrington Research reaffirmed a “buy” rating and set a $44.00 target price on shares of Perficient in a research note on Thursday, September 12th. Maxim Group reaffirmed a “buy” rating and set a $50.00 target price on shares of Perficient in a research note on Friday, November 8th. Finally, National Securities initiated coverage on shares of Perficient in a research note on Tuesday, October 22nd. They set a “buy” rating and a $46.00 target price on the stock. One research analyst has rated the stock with a hold rating, seven have assigned a buy rating and one has assigned a strong buy rating to the company’s stock. The stock has an average rating of “Buy” and an average price target of $41.83.
Perficient (NASDAQ:PRFT) last issued its earnings results on Thursday, November 7th. The digital transformation consultancy reported $0.56 EPS for the quarter, topping analysts’ consensus estimates of $0.52 by $0.04. Perficient had a net margin of 5.94% and a return on equity of 13.21%. The company had revenue of $144.68 million for the quarter, compared to the consensus estimate of $143.17 million. During the same period in the previous year, the firm earned $0.41 earnings per share. Perficient’s quarterly revenue was up 16.7% compared to the same quarter last year. On average, research analysts anticipate that Perficient will post 1.62 EPS for the current year.
Perficient Company Profile
Perficient, Inc provides information technology and management consulting services in the United States. The company designs, builds, and delivers solutions using middleware software products developed by third-party vendors. Its solutions include portals and collaboration, such as searchable data systems, collaborative systems for process improvement, transaction processing, unified and extended reporting, commerce, content management, and other services; and platform implementations services, including application server selection, architecture planning, installation and configuration, clustering for availability, performance assessment and issue remediation, security, and technology migrations.
Further Reading: What is meant by holder of record?
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Irony sweet irony. The December 2023 Brio Book Club pick selected Saving Time is taking longer to read so we’ve rescheduled for the new year.
This dazzling, subversive, and deeply hopeful book by Jenny Odell offers us different ways to experience time—inspired by pre-industrial cultures, ecological cues, and geological timescales—that can bring within reach a more humane, responsive way of living. As planet-bound animals, we live inside shortening and lengthening days alongside gardens growing, birds migrating, and cliffs eroding; the stretchy quality of waiting and desire; the way the present may suddenly feel marbled with childhood memory; the slow but sure procession of a pregnancy; the time it takes to heal from injuries. Odell urges us to become stewards of these different rhythms of life in which time is not reducible to standardized units and instead forms the very medium of possibility.
Saving Time tugs at the seams of reality as we know it—the way we experience time itself—and rearranges it, imagining a world not centered on work, the office clock, or the profit motive. If we can “save” time by imagining a life, identity, and source of meaning outside these things, time might also save us.
And a little about the author:
Jenny Odell is an Oakland-based artist, writer, and educator. Her writing has appeared in the New York Times, New York Magazine, The Paris Review, The Believer, McSweeney's, and Sierra Magazine. Her visual work has been exhibited internationally, including as a mural on the side of a Google data center in rural Oklahoma. Odell has been an artist in residence at the Internet Archive, the San Francisco Planning Department, and Recology SF (otherwise known as the dump). She is a lecturer in the Department of Art & Art History at Stanford University.

domain: literature


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A ship order better half is a woman who has selected a foreign nation to live in. A large number of women arrive from developing countries, and are sometimes in search of an improved life. Some of them also seek out a better man and better options for their kids. In order to be a productive mail buy wife, you should be prepared to spend a fair sum of money, which can be usually worth their expense in the long run.
Mailbox order brides to be are little women within their early to mid-twenties, and they are often divorcees or adolescent widowers. They seek a life in a better nation and want to get away from the cruel reality of their home country. Nevertheless , these ladies usually have a limited amount of money, and travel costs could be expensive.
Deliver order brides are generally readily available from a variety of countries, and some could even be local. In order to find a deliver order wife, you need to communicate with her for a decent period of time. While a woman will come from any country, it is critical to make sure that the info you furnish is correct and complete. You’ll need to set filters, and then assess the results.
A very good mail order wife is somebody who seeks a satisfying life in a foreign nation. She has selected a lifestyle that is not the same as her past life which is willing to whatever it takes to make this https://designnur.studio/2021/09/27/finding-a-wife/ happen. She is usually a good better half and a loving mom. She will place the needs of her family unit above her own.

domain: sociology


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Projects in detail
Lymph node FRC network
Defining the origin of lymph node and Peyer's patch fibroblastic reticular cells at single cell resolution
Secondary lymphoid organs such as lymph nodes (LNs) and Peyer’s patches (PPs) sample antigens from the body’s inner and outer surfaces and mediate optimal interaction of immune cells. These functions rely on the presence of specialized microenvironments that are built and maintained by fibroblastic reticular cells (FRCs). In addition to their scaffold-building function, FRCs impact on inducing and shaping innate and adaptive immune responses. However, we do not know the embryonic origin of these important cells and the molecular mechanisms underlying FRC differentiation in LNs or PPs. Our laboratory has generated the appropriate lineage-tracing and fate-mapping approach to address these questions. Accordingly, the work program of this project has been designed on the basis of two main hypotheses: (i) LN and PP FRCs originate from an organ-specific pluripotent embryonic precursor cell, and (ii) committed embryonic LN FRC progenitors descend from fat pad fibroblasts.
Only in recent years, the importance of secondary lymphoid organ stromal cells for induction and regulation of immune responsiveness has been appreciated. The field is now rapidly moving forward exploring functions and exploiting the potential of these cells as therapeutic targets in autoimmune diseases, cancer and infection. We anticipate that defining the origin of fibroblastic stromal cells and elaborating the mechanisms that govern subset differentiation in LNs and PPs will provide critical knowledge to further elaborate diagnostic and therapeutic avenues for various diseases.
Funded through Swiss National Science Foundation (SNF) Project Number 166500
Ontogeny and functional characterization of splenic fibroblastic reticular cells (FRCs) and their mesenchymal precursors during homeostasis, immune-activation and infection
Secondary lymphatic organs (SLOs) such as the spleen provide specialized microenvironmental niches for the development and control of immune responses. Particular mesenchymal stromal cells known as fibroblastic reticular cells (FRCs) generate distinct compartments that permit, for example, highly efficient interaction of T cells with dendritic cells. Importantly, FRCs are more than simple scaffold-building cells; these cells actively participate in inducing and shaping innate and adaptive immune responses. Our own preliminary data demonstrate that the structure and function of the splenic white pulp exclusively depends on lymphotoxin-beta-receptor (LTbR) signaling received by CCL19-positive FRCs during adult life and/or their putative progenitors, i.e. mesenchymal lymphoid tissue organizer cells (mLTOs).
In continuation of our existing collaborative activities, we have developed a novel inducible lineage-tracing model that permits genetic tagging of splenic FRCs and their progenitors in vivo and will thus facilitate the elucidation of their differentiation pathways throughout spleen development. In addition, this model system provides means for the identification and characterization of molecular mechanisms involved in the maintenance of splenic structure and immune-competence during adult life. Thus, in combination with our already established experimental model of cell type-specific loss of LTbR function, we will be able to resolve the temporal requirement of LTbR signaling for differentiation and function of adult splenic FRCs and their putative progenitors in the embryo.
Finally, using an experimental model that facilitates cell type-specific re-activation of LTbR expression in a timely controlled manner, we will test the hypothesis whether FRC-restricted LTbR expression within a specific time window is sufficient for proper white pulp formation and function during embryonic life. Furthermore, we will elucidate the requirements for a timely controlled LTbR activation during adult life in order to maintain compartmentalization and function of the splenic white pulp.
Our proposed objectives are based on our individual expertise and present the continuation of our successful collaborative activities. More specifically, they are designed to molecularly characterize splenic FRCs and to dissect lineage-relationship of splenic FRCs with other splenic stromal cells, e.g. their differentiation from mLTO precursors during embryonic development. Moreover, we will be able to identify and functionally characterize the cellular and molecular mechanisms through which LTbR–expressing FRCs are involved in the maintenance of lymphoid organ integrity and immune-competence in the adult spleen, i.e. their ecological role in the splenic micro-environment during immune homeostasis, activation and infection.
Funded through Swiss National Science Foundation (SNF): 159188
Defining the identity and differentiation pathways of the immune-stimulating fibroblastic tumor stroma
The tumor stroma has become an important area of research in recent years following the notion that stromal cell targeting therapies may provide a common therapeutic target for many tumor types. Although numerous studies have addressed the ways by which neoplastic cells alter their environment the origin, function and identity of fibroblastic cell lineages in the tumor microenvironment (TME) have remained largely unknown. These lapses in our basic knowledge of fibroblast differentiation in the tumor microenvironment make it difficult to define tumor-promoting versus tumor-suppressive fibroblasts, identify mechanisms of immune-stimulating fibroblast differentiation and their relation with tumor-associated tertiary lymphoid structures (TLS), and extrapolate large-scale bioinformatics analyses from cells in the bulk tumor to delineate cell- and lineage-specific differentiation pathways.
The overarching goal of the project is to define the differentiation and function of immune-stimulating fibroblasts within the lung following tumor-induced activation. This project is built on our working hypothesis that the lung stroma is composed of multiple fibroblast lineages, which exhibit immune-stimulating potential in the TME. Differentiation of immune-stimulating fibroblasts fosters the formation of TLS, which are niches that promote antitumor immunity and as such have an overall tumor-suppressive effect. To experimentally evaluate our model, we will combine the expertise and state-of-the-art models and methods from experimental and quantitative biology with a powerful computational approach to gain a comprehensive view of the fibroblastic lung tumor stroma.
The use of genetic models that label immune-stimulating fibroblasts will permit us to visualize and manipulate defined fibroblast lineages and to isolate these cells for further characterization. Using lung tumor models that exhibit peritumoral TLS, we will examine the distribution of immune-stimulating fibroblasts within the healthy versus lung tumor stroma and associated TLS. Furthermore, cell-specific ablation will reveal the functional impact of immune-stimulating fibroblasts on TLS formation and antitumor immunity. Having pinpointed relevant, tumor-associated fibroblast subsets, we will utilize new computational tools to create a data-based model of immune-stimulating fibroblast maturation in mice, which will serve as a platform to extrapolate related human fibroblast lineages. To this end, we will perform RNA-seq and mass cytometry on the single-cell level to comprehensively define phenotypes and functional states of fibroblasts in human lung tumors. The molecular map of human lung tumor fibroblast differentiation will be validated by single-cell transcriptomic and proteomic analysis of fibroblasts in tumor-free lung regions of the patients suffering from adenocarcinoma or squamous cell carcinomas. Overall, we expect that these studies will reveal putative therapeutic targets to bias the differentiation of immune-stimulating fibroblasts within the TME.
Funded through Swiss National Science Foundation (SNF): 177208
Dissecting the association of the human palatine tonsil microbiome and HPV-driven oropharyngeal squamous cell carcinoma
Oropharyngeal squamous cell carcinoma (OPSCC) can be caused by viral transformation of epithelial cells in the oropharynx such as high risk-human papilloma virus (HR-HPV). Importantly, the incidence of OPSCC has been increasing during the last decades although tumors with biologically active infection by HR-HPV exhibit a distinct biology and improved treatment response leading to better patient outcome. Recent studies have suggested that the containment of HR-HPV can be influenced by the microbiome present at mucosal surfaces and by microbial agents that persist within immune cells and thereby alter immune responses against the pathogen. Hence, we hypothesize that the microbiome of human palatine tonsils contributes to the establishment and persistence of HPV infection leading to malignant transformation and development of OPSCC. In particular, we assume that the microbial composition in left and right tonsils from the healthy individual is identical or at least very similar. Moreover, we expect to detect differences between the diseased and healthy tonsils of patients affected by OPSCC.
We plan to characterize the microbial composition of tonsillar surfaces and crypts in healthy individuals suffering from sleep apnae using next generation sequencing of 16S V5-V6 rDNA amplicons. We expect that this initial part of the study will fill a critical gap in the knowledge on the microbiome present in different compartments in tonsils of healthy adults. Next, we plan to profile the tonsillar microbiome of patients suffering from HPV-associated OPSCC and OPSCC that is not linked to HPV infection. We expect that evaluation of next generation sequencing and clinical data will provide novel knowledge on microbiome-HPV interaction and will found the basis for further prospective clinical studies. Finally, we plan to assess whether a distinct intracellular microbiome exists in immune cells within the tonsillar lymphoid tissue using multi-parameter flow cytometric analysis and cell sorting. We anticipate that these analyses will reveal whether and to what extent bacterial communities are associated with immune cells in human tonsils.
Overall, the outlined project will provide hitherto unknown information on the microbiome of different compartments in human tonsils, support design of future prospective clinical studies to clarify the role of the microbiome in HVP-driven OPSCC and direct future analyses of immune cell-commensal bacteria interaction in tonsillar lymphoid tissue.
Funded by the San Salvatore Foundation
Constructing accessory lymph nodes in situ for control of mammary carcinoma
Lymph nodes (LNs) are situated at junctures of the blood vascular and the lymphatic system where antigens drain from peripheral tissues via afferent lymphatics. The decision whether and how immune responses against tumors are initiated and maintained is made in local tumor-draining LNs. During the development of malignant breast cancer, new LNs emerge within the glandular tissues that are normally devoid of LNs. However, we do not understand the mechanism of development of these LNs and their role in antitumor immunity. Thus, the novel hypothesis underlying the planned research is that de novo LNs appear in the vicinity of breast cancer as an accessory “base camp” for the initiation and maintenance of antitumor immunity. Here, we combine and leverage knowledge and experimental tools in immunology, vascular biology, cancer biology, and bioengineering to address the hypothesis in three specific aims:
1) To dissect the molecular pathways of tumor-induced development of accessory (a)LNs with a particular emphasis on lymphovasculokines.
2) To determined to which extent aLNs support antitumor immunity.
3) To stimulate formation of aLNs in mammary tissues to foster antitumor immunity.
The project is conceptually innovative because a deeper understanding of the interplay between aLNs and tumors may not only lead to a novel approach to cancer treatment, but could also help to establish a novel prevention paradigm in cancer medicine. The aims of the project will be addressed in a cooperative manner and activities in each group will contribute to address the global aims of the project. Gain of knowledge on the basic molecular principles involved in aLN formation (major aim 1) will absorb the major part of the activities. Determination of the impact of aLNs on antitumor immunity (major aim 2) will be assessed in cooperation between the three groups. Finally, formation of aLNs in tumor-draining areas in vivo (major aim 3) will be assessed by using highly innovative approaches including implantation of LN-like stromal cell spheroids and optogenetic induction of molecules that foster activation of the aLN anlage. In sum, the combination of the special expertise of the applicants in LN development, lymphovasculokine biology and optogenetic technology is crucial for addressing the ambitious project aims and therefore secures the basis for successful execution of the research plan.
Funded through Human Frontier Science Program (HFSP)

domain: biology


text:
Amy was wonderful and the music was just right for our event. She helped make our evening event wonderful and everyone thoroughly enjoyed the music. Brovo Brovo
Hired as: Harpist
Response from Magical Harps by Amy Lynn Kanner:
Thank you so much for your enthusiastic review, Peg! I thoroughly enjoyed playing for your event, and I would love to play again for any future celebrations you might have. Wishing you a special holiday season, and a New Year filled with happiness and adventures!

domain: entertainment


tassel bandana | fall 22 | freshman
a two-toned oversized bandana scarf that features tassels all around the border. made in our freshman / sophomore textile, a midweight doublecloth featuring a multicolored plaid of pink, blue, black, yellow and orange.
- made in India.
- 100% organic cotton
- machine wash cold or dry clean, tumble dry low
this textile is made with 100% GOTS (Global Organic Textile Standard) non- GMO organic cotton without the use of harmful chemicals and synthetic fertilizers.
Brittany is 5'8" and wears our tassel bandana in the freshman / sophomore textile, styled with our greta dress in campus.
os: 25” long, 25” wide, +/- a tolerance natural to the sewing process


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Other popular processors from the Ryzen 4000 U lineup are the Ryzen 3 3400U and 7 4700U with 5 and 7 graphics cores, respectively. Posted by 2 months ago. Intel Core i5-10210U vs AMD Ryzen 5 4500U: 11. As a mid-tier member of the Ryzen 4000 U family, the six-core Ryzen 5 4500U sits between the slightly faster eight-core Ryzen 7 4700U and weaker quad-core 3 4300U. Buy Xiaomi RedmiBook 13 Laptop Ryzen Edition Notebook AMD Ryzen 4700U/4500U 13.3 Inch Display 512GB/1T SSD Windows 10 Computer at cheap price online, with Youtube reviews and FAQs, we generally offer free shipping to Europe, US, Latin America, Russia, etc. AMD Ryzenâ¢ 5 Mobile Processors with Radeonâ¢ Graphics. 4500U vs i5-10210U specifications comparison The charts below compare the most important characteristics of the i5-10210U and Ryzen 5 4500U CPUs. It has 2.30 GHz â 4.00 GHz base and boost clocks which are pretty respectable because the i7-1065G7 has lower ones â 1.30 GHz â 3.90 GHz. AMD Ryzen 7 3700U vs Intel Core i7-1065G7: 13. AMD Ryzen 7 4700U had the most wins, coming in first place for 92% of the tests. Do people think it's worth it to spend $70 more to get the i7-4500U instead of the i5-4200U? Without further ado, letâs go straight to results. In multi core, it â¦ CPUBoss is not aware of any important advantages of the Core i5 5200U vs the Core i7 4500U. 1 3 31. AMD Ryzen 7 4800U/4700U laptops â specs, benchmarks and complete list of devices By Andrei Girbea - @ andreigirbea , last updated on November 25, 2020 AMD are finally able to properly compete with Intel in the ultrabook space with their Renoir hardware iteration, and not just in the budget segments, as in recent years. So in cases where the Ryzen 7 PRO 4750U can't shine with its eight cores / sixteen threads, in some cases the 4700U does still lead the race. ... Tiger Lake is impressive for it's single core performance (thanks to super duper large 1.25 MB L2 + 12 MB L3 cache vs 512 KB L2 + 4 MB/CCX L3 in Renoir). AMD Ryzen 5 4500U vs AMD Ryzen 7 4700U Comparison of the technical characteristics between the processors, with the AMD Ryzen 5 4500U on one side and the AMD Ryzen 7 4700U on the other side. The Ryzen 7 4700U features 7 compute units inside, which can offer 1080p gaming capability. Graphics specs wise, Ryzen 7 4700U has Radeon RX Vega with 7 CUs and Ryzen 5 4500U has only 6 CUs. You may want to search for core i7-4500U vs i5-4200U on youtube for a great discussion about it. If there's enough discount on the 4500U model, it might be worth it. AMD Ryzen 5 4500U vs AMD Ryzen 5 3500U Comparison of the technical characteristics between the processors, with the AMD Ryzen 5 4500U on one side and the AMD Ryzen 5 3500U on the other side. Laptop May 20, 2020 by David. On this page, you'll find out which processor has better performance in benchmarks, games and other useful information. This is an overview of the AMD Radeon integrated graphics processor of the AMD Ryzen 5 4500U main processor for laptops. But letâs be realistic: Itâs a limited thermal envelope with only LPDDR4X/3733 vsâ¦ å¥æ°æ¬¾æ¯åçº¿ç¨çï¼å¯ä»¥çè§£æååï¼æ r5-4500u å r7-4700u. å¤çº¿ç¨çæ§è½ï¼å¹¶ä¸æ¯åçº¿ç¨çä¸¤åã New appearances in 3DMark put two new versions of Xiaomi Redmibook on the scene, these are based on the Ryzen 5 4500U and the Ryzen 7 4700U, which are two of â¦ Xiaomi Redmibook with AMD Ryzen 5 4500U, Ryzen 7 4700U sighted in 3DMark. Based on the geometric mean of all complete results, the fastest (AMD Ryzen 7 4700U) was 1.143x the speed of the slowest (AMD Ryzen 5 4500U). The walmart version lists for $579, but has apparently been $500 previously (maybe a deal is coming). AMD Ryzen 5 4500U vs AMD Ryzen 7 4700U: 12. The first is dedicated to the laptop sector, It has 6 cores, 6 threads, a maximum frequency of 4.0GHz. Any thoughts on the 4700U with 512gb vs 4500U with 256gb? AMD Ryzen 5 4500U vs. AMD Ryzen 7 3700U - Benchmark, Geekbench 5, Cinebench R20, Cinebench R23, Cinebench R15 and FP32 iGPU (GFLOPS) benchmark results www.cpu-monkey.com Last edited: Jun 6, 2020 The Ryzen 7 4700U does have a higher base clock frequency than the Ryzen 7 PRO 4750U (2.0GHz vs. 1.7GHz) while both having a 4.1GHz peak boost clock. The 4500U is a 6-core processor with no SMT â that means there are no additional logical threads. The 15-Watt 5 4500U directly competes against Intelâs 15-Watt 10th Core i5 U and G series series. One of the areas where Hyper Threading still tends to be beneficial is in code compilation with multiple parallel jobs so not at all surprising to see the 12-thread 9750H have a slight lead here. Comparative analysis of AMD Ryzen 7 4700U and AMD Ryzen 5 4500U processors for all known characteristics in the following categories: Essentials, Performance, Memory, Graphics interfaces, Compatibility, Peripherals, Advanced Technologies, Virtualization, Graphics. AMD Ryzen 5 4500U CPU Based Notebook Tested â 7nm Zen 2 Cores On Par With i5-9600K, Vega 6 iGPU Delivers Huge Boost in GPU Performance By Hassan Mujtaba Feb 9, 2020 08:38 EST These features, together with an IPC (instructions per cycle) number, determine how well a CPU performs. VivoBook_ASUSLaptop X521IA_M533IA AMD Ryzen 7 4700U 2000 MHz (8 cores) Uploaded Sat, 19 Dec 2020 22:17:56 +0000. It's strange how 4700u is barely 10% faster than 4500u when in theory 4700 should be almost 24% faster (7/6*1600/1500=1.24). AMD Ryzen 7 4700U We compared two laptop CPUs: the 1.6 GHz Intel Core i5 8250U with 4-cores against the 2 GHz AMD Ryzen 7 4700U with 8-cores. Platform. The first is dedicated to the laptop sector, It has 6 cores, 6 threads, a maximum frequency of 4.0GHz. Benchmarks Real world tests of Core i7 4500U vs i5 5200U CompuBench 1.5 (Bitcoin mining) Data courtesy CompuBench It is also a great choice for budget computing, but if you prefer more performance, better versatility, and higher efficiency â there is only one choice. I also am debating what is a better deal, this or the 4500U walmart version with a 256gb drive. The Ryzen 7 4700U wasn't far behind and the Ryzen 5 4500U showing remained strong. åä»£éé¾ä½åuå¸é¢ä¸å¸¸è§çå°±åä¸ªæ¬¾ï¼4500u, 4600u, 4700u, 4800uã å¶æ°æ¬¾æ¯æå¤çº¿ç¨çï¼å¯ä»¥çè§£æååæµï¼æ r5-4600u å r7-4800u. Intel i5-1135G7 vs AMD R5 4500U (hint: not impressed) Close. Platform Windows Single-Core Score 669 Multi-Core Score 3842 System Acer Swift SF314-42 AMD Ryzen 7 4700U 2000 MHz (8 cores) Uploaded â¦ Amazingly, Acer Swift 3 SF314-42-R0ND and Asus Vivobook D433-X421 Laptop models are tested to run Cinebench R20, CS:GO, PUBG, Call Of Duty: Modern Warfare and Dota 2. But with iGPUs and those games/quality settings this â¦ All laptops with AMD Ryzen 5 4500U: AMD Ryzen 5 4500U vs. AMD Ryzen 7 4700U - Benchmark, Geekbench 5, Cinebench R20, Cinebench R23, Cinebench R15 and FP32 iGPU (GFLOPS) benchmark results AMD Ryzen 7 4700U vs AMD Ryzen 7 3700U: 10. These features, along with an IPC (instructions per cycle) number, determine how well a processor performs. Inspiron 5505 - AMD 4700U / 4500U - Fix the hardcoded VRAM in BIOS Starting this thread as a placeholder and feature request thread for all Inspiron 5505 owners. There are several possible reasons for that I can think of: GPUs are CPU bottlenecked. If you are looking for AMD ryzen laptops you need to understand that ryzen is one of the latest and expensive processors at this time. AMD Ryzenâ¢ 7 Mobile Processors with Radeonâ¢ Graphics. Ryzen 7 4700U / Ryzen 5 4500U 15.6" FHD Panel 8GB (1x8GB) SODIMM 3200Mhz 256GB NVMe SSD (2x) NVMe Slots Intel WiFi 6 AX200NGW Aluminum Palm Rest High Screen to Body Ratio Numpad US English Keyboard Dual Channel Support (2x SODIMM Slot) [Officially up to 32GB RAM]** ** Unofficially, 64GB of RAM should work. AMD Ryzen 7 3700U vs Intel Core i7-8550U: 14. The specs seem like slight improvements in performance for 15% higher price . So it will be harder to find a great option in budget. The latter has 4 cores and 8 threads and its cache size is 8MB â the same as 4500U. The Radeon version built into the Ryzen 5 4500U chip has six graphics processing cores. I was initially put off by there not being any 16gb models being available at a good price, (it's $999.99 for 4500U with 16gb, and a couple hundred bucks more to get it with a 4700U almost from what I saw), but after doing some research I learned that the difference between 8gb and 16gb in these APU type cpus do not make a big difference if any at all in most tasks, including gaming. Intel Core i5-8265U vs AMD Ryzen 7 3700U: 15. Although the Ryzen 5 4500U is the deal here, we shouldnât downplay its predecessor. While the 4700U is 20% faster than the 4500U in multi-thread and 5% faster for single-thread, the 8 core 8 thread design isnât faster than the 6 core 12 thread Ryzen 5 Pro 4650U a.k.a. Laptop Sam_K (03:34 AM, July 28, 2014) I'm looking for some advice. AMD Ryzen 5 4500U vs AMD Ryzen 5 4600H vs AMD Ryzen 7 4700U - Benchmarks, Tests and Comparisons This is our first review of AMD's Ryzen Mobile 4000 U-series processors, the low power variants intended for slim, light, ultraportable laptops. 4500U vs 4600H specifications comparison The charts below show the difference between AMD 4600H and Ryzen 5 4500U most important characteristics. Platform. overall i feel the ryzen and i7 both are balanced in thier own ways though ryzen has more performance power as it has 6 cores and 6 threads but intel has 4 cores and 8 threads. AMD Ryzen 7 4700U vs AMD Ryzen 5 4500U. Intel Core i5-8250U vs AMD Ryzen 7 3700U: 16. Please raise a Service Request to Dell to fix the hardcoded VRAM (512 MB in BIOS). Looking at the Yoga Slim7 4700U and 4800U They come in the same package and have a few differences listed at the bottom.


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A large part of sleep research is dedicated to finding the exact part of the brain that is most responsible for our ability to sleep deeply and restoratively. Determining exactly what that area is represents the first step in developing a targeted medication that will truly provide rest for those afflicted with a number of different sleep disorders. Now scientists from the Imperial College London believe that they have pinpointed that region in the brain in mice, and are hopeful that their research will lead to a breakthrough for human insomnia. Continue reading
Smart six chamber technology with separate lumbar adjustment ensures personalized comfort for each side of the bed.
Dual chamber technology allows you to customize each side of the bed to your preferred level of comfort and support.
- Adjustable Bases

domain: medical


5G and Cloud are two inextricably linked technologies. 5G will bring a massive change to cloud computing and revolutionize every business sector man works in. CSPs will need multi-purpose, high-fidelity, real-time visibility across all layers of the network to assure performance. Ideally, they will want a solution that offers a single, integrated platform that works on any legacy or cloud-based network.
Mavenir is building the future of networks and pioneering advanced technology, focusing on the vision of a single, software-based automated network that runs on any cloud.
Sanjay Bakaya, Country Head- India & Regional Vice President- India & South Asia at Mavenir, tells us more. Excerpts from an interview:
V&D: How is Mavenir building the future of networks with cloud-native software?
Sanjay: We are building the future of networks with cloud-native software that runs on any cloud and transforms the way the world connects, realizing new services and the promise of 5G and beyond.
For example, the Converged Packet Core Solution providing an end-to-end fully containerized 5G Core product portfolio with combo nodes for 2G/3G and 4G support.
Another example is the Mavenir WebScale Platform, where operators can now run applications not just in large central data centers, but also out to the edge and into enterprises.
It is the common software across Mavenir products and services that enables agility and speed in the delivery of new applications, as well as the adoption of new technologies. It is unique because it brings the best practices from the hyper-scale cloud and IT industries for rapid design, development, testing and rollout.
V&D: What are the examples in India, so far?
Sanjay: Indian Communication Service Providers (CSPs) are closely engaged with us on our Core and OpenRAN for both 4G and 5G, joint innovation for the development of an ecosystem to have a deployment of this technology at a scale to achieve cost efficiency to provide more choice to operators and compete with legacy equipment providers.
It is a tectonic shift from a traditional vendor locked vertically integrated approach that have to be forklifted with every new G. OpenRAN provides dis-aggregated solutions using Commercial-Off-The-Shelf (CoTS) equipment and Open interface based radio head partners.
Our solutions in Packet Core, IMS, OpenRAN, Messaging etc. are already deployed and in use at various CSPs in India. We also participating in the BSNL 4G requirements to contribute towards building a self-reliant India in the Telcom gear space.
V&D: Do you think a common 4G/5G network is the immediate future for operators?
Sanjay: 5G networks are designed to work in conjunction with 4G networks using a range of macro cells, small cells and dedicated in-building systems. With the advent of widespread Internet of Things (IoT) adoption in enterprise applications including manufacturing, agriculture, healthcare, and more, alongside an increasing dependence on smartphones and always connected computers, the constraints of 4G LTE technology are prompting mobile network operators to embark on an accelerated rollout of 5G communications to keep pace with the network demands of today and the very near future.
Now is the time for operators to look towards virtualization to prepare for the 5G future. Our Cloud-Native, disaggregated and virtualized solutions are the best option for having a network ready for 5G while continuing to serve existing 4G customers on the same infrastructure.
The Converged Packet Core solution uses cloud-native architecture with granular microservices, following web-scale principles which provide the required scalability, agility, and reliability to meet the wide range of 5G use cases and stringent 5G performance requirements for e2e latency, high throughput demand and overall network availability.
V&D: How will you provide enhanced wireless coverage for rural communities?
Sanjay: With the pandemic pushing employees to work from home and students to remote learning environments, gaps in internet access have become more prevalent, the opportunity to provide better coverage to rural communities are available to local carriers through increased access to the spectrum. The rural market requires a solution that can economically support the small number of users in that geography.
We have been participating and driving OpenRAN business transformation which is a low-cost solution for the rural market & will have better TCO in the urban market as well. Our OpenRAN solution can help CSPs to extend their wireless coverage to rural communities cost-effectively.
V&D: How are the enterprise private networks evolving?
Sanjay: Historically, CSPs have built, operated, and owned mobile and fixed wireless networks. Now, as digital transformation shifts priorities within enterprises and industries, organizations find value in owning, managing, and operating their own network, and that demand is growing. Easier access to spectrum, more flexible open network options and a growing ecosystem of integrators and niche Service Providers (SPs) is making private cellular far easier, even as demand grows with IoT and industrial transformation.
CSPs too are considering ways to tap into the burgeoning enterprise and industry transformation opportunity. Also, the pandemic prompts enterprises and governments to pull forward and broaden the scope of their digital transformations, primarily for business resiliency and cost‐reduction purposes, but also for tapping into new market opportunities. There is significant interest across verticals in leveraging 5G, as well as other new technologies such as AI and Edge Computing, to adapt economies and societies to the new normal.
V&D: How are you cloudifying your own portfolio?
Sanjay: We believe that cloud-native is the way of the future, having watched the large enterprise, webscale players such as Facebook, Amazon, Netflix, Google operate at a super large scale. We have expanded and cloudified our portfolio with various solutions such as WebScale Platform, AI & Analytics, Multi-Access Edge Computing (MEC), and Digital Enablement Platform.
These solutions support the ongoing cloudification of the mobile networks to enable CSPs to meet the growing data demands on their networks. Mavenir Webscale Platform (MWP) is a next-generation cloud-native solution that includes Kubernetes based CaaS (Containers as a Service), PaaS (Platform as a Service) and MTCIL (Telecom PaaS layer) along with a management layer that includes full FCAPS, analytics, slice management and service orchestration.
This helps in moving applications to Commercial-Off-The-Shelf (COTS) computing servers and embracing a complete ecosystem with applications in the Cloud (private, hybrid or public) and bring automation to improve the way operators manage and operate their networks. Also, to CSPs, this provides more flexibility and agility enabling the introduction of new services not only in the traditional consumer business but also in the enterprise arena.
V&D: What will be the impact on transportation and transmission for 5G networks?
Sanjay: We all know that 5G is going to provide much higher bandwidth than the previous generation of telecom services. Support of higher bandwidth also going to put pressure on the underlying transport network infra, so this needs to be enhanced and modernized. The impact will not be just on capacity as 5G Use cases apart from bandwidth (eMBB) will also require ultra-reliable low latency communication (URLLC), Massive Machine Type Communication (mMTC) & higher scalability.
All this requires transport networks just not to be upgraded but re-architected as well. On the Radio side with Massive MIMO and distributed RAN architecture, various requirements will be imposed on the transport network connecting these (RRU, DU & CU) systems positioned at various locations supporting various topologies in line with CSP strategies.
Due to various 5G Use cases, traffic pattern in 5G will be much more dynamic, it is expected that the underlying transport network should be able to react in near real-time to meet these changing demands.
V&D: What are your future plans?
Sanjay: We are building a strong team to engage with mobile operators and change the mobile network economics through innovation and software. We have over 3000+ full-time engineers in India/South Asia region with offices in Bengaluru, Mumbai and Gurugram, and we plan to further expand our R&D Center at Bengaluru. We will be innovating and working on opportunities for data core and virtualized RAN-based on the Open RAN global initiative, besides leveraging our strong global VoLTE experience by supporting our customers in shifting from legacy circuit-switched systems. Going forward, we will be offering innovative, new services that will generate revenues for operators.


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domain: game


IDC Survey of 18 Vertical Markets Finds Restrained Optimism for Business Prospects in 2003
FRAMINGHAM, MA – APRIL 8, 2003 – IDC’s latest survey of North American businesses in 18 vertical industries indicates that, although the short-term economic outlook is improving, businesses are tempering their enthusiasm. When asked about their business prospects in 2003, these same organizations responded similarly restrained optimism.
Although attitudes about the economic and business outlook do not directly point to an upturn in technology spending, these attitudes do help gauge the tone of an industry. IDC research reveals that the average IT budget growth rate for 2003 across North American organizations will be 3.2%, driven by increases among mid-market companies. Large variations exist across industry segments, but the following trends provide an overall view of the situation and expectations for 2003:
North American organizations in the aggregate spent 5% of their revenue or operational budget on IT in 2002. This share is expected to grow in 2003, reflecting diminished revenues for some industries and budget cuts impacting areas other than IT more severely.
Over three-quarters of surveyed companies ranked "Exploit our existing markets more efficiently" as their number 1 business priority for the next 12 months and 79.4% stated that total IT spending in 2003 will stay the same or increase in comparison to 2002.
Top priority areas for IT investments in 2003 most often include CRM, systems infrastructure, and industry-specific solutions.
"The current economic uncertainty is clearly felt in our survey findings," said Lucie Draper, program manager for IDC's Enterprise Technology Trends, Vertical Markets group. “For a majority of organizations, the strongest decision criterion in evaluating and justifying IT investments is that the project will contribute to lowering costs and expenses. IT expenditures are now perceived as ‘project driven’ rather than ‘budget driven,’ and those projects that are considered critical to remain competitive and cost effective will continue to be implemented, despite the economy.”
Although the focus on IT spending was on systems infrastructure and security solutions in 2002, this year CRM solution vendors are poised to see the biggest gains, IDC’s research shows. However, many companies made significant technology purchases over the last two tothree years and are now trying to put it all to work and provide the return on investment sought.
The end-user data presented in this study, IT Decision Monitor 1Q03:
Vertical Markets' Economic Outlook and Business Prospects Shaping IT Budgets and Investment Priorities, (IDC #28918), derives from IDC's Enterprise Technology Trends (ETT) research program. The research provides analysis across 18 vertical markets and three company size segments and offers a look at ways in which the economic climate affects perceptions of business prospects and how the outlook is changing over time. It offers detailed information on IT budgets and budget directions for 2003 and provides a glance at past, present, andfuture IT solution investment areas and top IT investment priorities.
Findings presented were gathered over three distinct periods:
May/June 2001, December 2001/January 2002, and September/October 2002. This allows IDC to capture the change in attitudes and behaviors. Quarterly updates will be developed.
To purchase this document, call IDC's sales hotline at 508-988-7988 or email firstname.lastname@example.org.
For additional information about IDC’s Enterprise Technology Trends research, please contact Virginia Lehr at 508-935-4188 or email at email@example.com.
IDC is the foremost global market intelligence and advisory firm helping clients gain insight into technology and ebusiness trends to develop sound business strategies. Using a combination of rigorous primary research, in-depth analysis, and client interaction, IDC forecasts worldwide markets and trends to deliver dependable service and client advice. More than 700 analysts in 43 countries provide global research with local content. IDC’s customers comprise the world’s leading IT suppliers, IT organizations, ebusiness companies, and the financial community. Additional information can be found at www.idc.com.
IDC is a division of IDG, the world’s leading IT media, research, and exposition company.
# # #
All product and company names may be trademarks or registered trademarks of their respective holders.


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The Prodigy are touring this July with a series of live dates in England to coincide with the 25th anniversary of their legendary album The Fat Of The Land.
But what are the tour dates and times – and are there still tickets?
Here’s what you need to know.
What are The Prodigy’s tour dates?
Back in March, the group wrote on social media: “We can’t wait to get back on stage and play our tunes for the people again. The 25th anniversary of ‘Fat Of The Land’ felt like the right time for us to take a step forward.”
The group will play gigs in Sheffield, Liverpool, Leeds, Birmingham, Newcastle and Manchester before playing three nights in Brixton, London.
This is the full list of tour dates:
8 – O2 Academy, Sheffield – 7pm
9 – O2 Academy, Sheffield – 7pm
14 – Mountford Hall, Liverpool – 7pm
3pm – O2 Academy, Leeds – 7pm
4pm – O2 Academy, Birmingham – 7pm
6pm – O2 City Hall, Newcastle – 7pm
7pm – O2 Victoria Warehouse, Manchester – 7pm
21 – London O2 Academy, Brixton – 7pm
22 – London O2 Academy, Brixton – 7pm
23 – London O2 Academy, Brixton – 7pm
The group have already played gigs in Sheffield, Liverpool and Leeds but will continue their tour in Birmingham on Saturday (July 16).
Corresponding ticketmastertickets are limited for Birmingham, Newcastle and the first two of the three Brixton dates, with limited availability for the Manchester gig and the last Brixton date.
Ticket prices range from £51.90 to £67.65.
Who is the support act?
There is currently no support act on The Prodigy tour.
What is the setlist?
A setlist for the Birmingham gig has not yet been announced, but according to Setlist.fm, this was the tour’s setlist so far:
- To breathe
- Wild Frontier
- light up the sky
- All in place
- Voodoo people
- Firestarter (Instrumental Remix Featuring Keith Flint Laser Outline)
- your law
- Not good (start the dance)
- Join your fight
- Need something1
- Blow up my bitch
16. Take me to the hospital 17. Invaders must die 18. We live forever 19. Out of space

domain: artistic


text:
Director: Leroy Kincaide.
With: Johnny Fleming, Kit Smith, Bethan Waller, Ian McNaughton.
UK 2021. 105 mins.
FIRST BLOOD WORLD PREMIERE -
A vibe of true horror coupled with the dank sense of uncertainty. Fact can be stranger and more terrifying than fiction. Medical student Lucy, suffering from sleep paralysis, finds herself plagued by a demonic entity after moving in with her boyfriend. Torn between sanity and the unknown, Lucy seeks help from a local priest forced to make a deathly choice. With the clock ticking, will Lucy escape the dark force consuming her from inside? Actor-turned-writer/director Leroy Kincaide makes his accomplished feature debut with a stark supernatural horror, one inspired by Kincaide’s own real-life paranormal experiences.


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As Nicki Minaj makes her rounds in support of her upcoming album, The Pink Print, she lands a new magazine cover for the Autumn/Winter issue of U.K. fashion magazine Dazed.
She’s featured on a double-cover, shot by Jeff Bark, which features two sides of the rap star — including a demure fashion obsessive and a provocative pop culture bombshell. On one cover, Nicki rocks a pink tweed Chanel jacket, while fixing a bologna sandwich. The other, she strips down into silk La Perla undergarments and a Miu Miu coat and plastic boots while seated on a diving board.
The issue hits newsstand Thursday (Sept. 11).


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Moviegoers have a chance to relive the cinema experience and return to O Cinema.
After a full year of shutdowns and limited entertainment, the Miami Beach theater reopened on March 19. This means in-person experiences AND virtual screenings – whichever you choose!
To keep up with latest news, sign up for the daily Miami on the Cheap newsletter. You can also follow us on Facebook and on Twitter and visit our Facebook group page.
The featured movies will continue changing, so please check O Cinema’s calendar for the most current offering.
Movie tickets are available online and at the box office, at 1130 Washington Ave. Prices are as follows:
- Adults – $11
- Seniors age 62 and older – $9.50
- Students & teachers – $9.50
- Children age 12 and younger – $9.50
- Military – $9.50
- O Cinema members – $7.50
- Miami Beach resident discount: 20 percent off adult tickets on the first Monday of every month (with valid proof of residency)
In announcing the reopening, O Cinema officials made clear their health and safety precautions and regulations. These include:
- Mandatory facial coverings
- Entrance screenings
- Social distancing measures, including seating arrangements
- Reduced capacity
- Hand sanitizer
Hesitant to go indoors?
For those who are not ready for an indoor movie experience, O Cinema continues to offer virtual movies. Tickets for online offerings range in price from $10-$12.
The current schedule includes, among others:
- “Truth to Power”
- “17 Blocks”
- “76 Days”
- “Through the Night”
- “A Glitch in the Matrix”
- “The People vs. Agent Orange”
Two FREE screenings are also planned. These will only be available online:
“Oliver Sacks: His Own Life” – Monday, April 5
- “F11 and Be There” – Monday, May 3


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Here Dave Turnbull, CEO of the BMC, gives the first BMC New Year Address to the UK's mountain community providing an overview of the BMC's work in 2007 and the challenges that lay ahead in 2008.
As recently reported, a team of young British alpinists consisting of Uisdean Hawthorn, Ben Silvestre and Pete Graham established... Read more
31 year old Austrian climber Angela 'Angy' Eiter has become the first woman to climb 9b, according to a post by 8a.nu. Angy... Read more
US climbers Brad Gobright and Jim Reynolds have shaved four minutes off the previous record for climbing The Nose on El Capitan... Read more


Wisconsin accountability board: ‘We will not strike them unless challenged’
Rivers of America filled with pacifiers - The Daily Caller
What do you find at the bottom of an amusement park basin after seven years?
We’re not sure if this portends a robot Mickey Mouse and Snow White, but Korea plans to build what is believed to be the world’s first robot theme park, the Korea Herald reports. The robot magic kingdom will be part of a giant residential and industrial complex called Robot Land in Incheon, one of South Korea’s largest cities and a major transportation hub


text:
Source of the Challenge
- 11 Downloads
The economic distance between nations can be measured in many ways. The most widely used and probably the most misleading of these measures is that of annual income or gross national product per head. On the one hand it exaggerates the gap between rich and poor nations, making one despair of ever seeing that gap close significantly, and on the other it diverts attention from the real and tragic differences between the lives of the poor and the rich. What meaning can be attached to the statement that the national income per capita in the United States is $5,000 while in India it is $100?1 Does it really mean that the average American citizen is fifty times better off than the average Indian? In one sense this is patently absurd. Merely to survive, to be able to buy enough basic food, clothing and shelter in the United States would cost over $1,000 while $100 would suffice for these in India, so that someone with $1,000 in America may be worse off than someone in India with $100. The fault lies in the fact that the international exchange rate between the Indian rupee and the American dollar does not reflect the domestic purchasing power of these currencies. In both of these nations foreign trade is a mere 5 per cent of total national product, yet only this tiny part affects directly the exchange rate.
KeywordsCapita Income Real Wage Rich Country Green Revolution Advanced Country
Unable to display preview. Download preview PDF.
- 3.Edward G. Mishan, The Costs of Economic Growth (London: Staples, 1967) gives a lively account of some of these factors. Also see Usher, op. cit.Google Scholar
- 4.A. Krueger, ‘Factor Endowments and Per Capita Income Differences Among Countries’, Economic Journal, September 1968.Google Scholar
- 5.I. Adelman and C. T. Morris, An Anatomy of Patterns of Income Distribution in Developing Nations, Report from USAID, 12 February 1971.Google Scholar
- 7.Mahbub ul Haq, ‘Employment in the 1970s: New Perspective’, International Development Review, December 1971.Google Scholar
- 17.F. James, Levinson, ‘Facilitating Effective Investment in Nutrition’, International Development Review, No. 4, 1972, p. 19.Google Scholar
- 37.J. H. Boeke, Economics and Economic Policy of Dual Societies (New York: Institute of Pacific Relations, 1972) p. 40Google Scholar
- quoted in Walter Elkan, An Introduction to Development Economics (Harmondsworth: Penguin, 1973) p. 35.Google Scholar
- 38.Kusum Nair, Blossoms in the Dust: Human Factor in Economic Development (New York: Praeger, 1962).Google Scholar
- 42.See P. K. Bardhan and T. N. Srinivasan, ‘Cropsharing Tenancy in Agriculture: Theoretical and Empirical Analysis’, American Economic Review, March 1971;Google Scholar
- and S. N. S. Cheung, The Theory of Share Tenancy (Chicago: Chicago University Press, 1969).Google Scholar

domain: finance


201805 Versioned API
WIP -- Work in Progress
Submitting WG/Project/Implementer Group
FHIR-I + ITS
Proposed Track Lead
Kevin Olbrich See Connectathon_Track_Lead_Responsibilities
Many server operators and clients have been implemented on a variety of FHIR versions. In order to facilitate supporting newer versions of FHIR, it is necessary to work out mechanisms by which multiple FHIR versions can be supported side-by-side. Otherwise we run the risk of locking both vendors and consumers into legacy versions of FHIR due to the operational difficulty of migrating.
Interest is growing in how to manage cross-version use of the FHIR API. This connectathon stream tests out 2 aspects of cross-version use of the FHIR API:
a single end-point that supports more than one version (Scenarios #1 and #2) how to handle changes a resource between versions (Scenarios #3 and #4)
Kevin Olbrich (McKesson)
Approaches to Versioning
The simplest approach to versioning is to include a version identifier in the URL of the FHIR server (e.g, `https://test.fhir.org/r4`). While this approach is easy to implement it suffers from several limitations. Assuming a consuming service stores a reference to a patient as `iss=https://test.fhir.org/r4 ref=Patient/123` then several problems arise. 1. The server operator needs to maintain that URL indefinitely or they run the risk of breaking consuming applications. 2. The URL makes promises about the version, so the server operator would need to ensure that the url continued to serve resources in the appropriate version 3. The client is also obligated to maintain the ability to read/write older versions of the FHIR standard as long as the record continues to point to the old version 4. The FHIR version of the Resource is not semantically meaningful for the most part. Consuming applications really are interested in references to a particular resource and the FHIR version is a detail that needs to be worked out for communication. 5. The sever operator needs to ensure that changes to a record are reflected in all supported versions, which may impose a high operational and support cost.
An alternative approach to server versioning that follows web-standard MIME-type negotiation.
In this approach the server operator inspects the incoming `Accept` header of a request and uses this to determine which version of FHIR to respond with. The `Accept` header should be formatted like
(and/or the xml equivalent, if desired). The FHIR version is specified by adding the `fhirVersion=X.X` parameter to the mime type, where `X.X` is the major.minor version of FHIR that is requested. (Patch level versions are generally considered to be unimportant for API changes and may be ignored by the server). The server operator should use the first specified type that they support. The server should acknowledge that it has recognized and responded with a specific FHIR version by including a Content-Type header in its response.
Please include information here regarding how much advance preparation will be required if creating a client and/or server.
Role 1 Name
Scenario Step 1 Name
- Success Criteria:
- Bonus point:


text:
Four Seasons Resort Whistler
Four Seasons Hotels and Resorts specialize within the hospitality industry, by offering only experiences of exceptional quality. Now Four Seasons unveils renowned comforts, relaxed luxury and caring service in the world-class year-round resort of Whistler. Four Seasons Resort Whistler rests at the base of Blackcomb Mountain, a short walk or shuttle to the Blackcomb ski lifts and a short shuttle to the village and Whistler Mountain. With 242 guest rooms, suites and townhouses, the Resort evokes the spirit of luxurious mountain residence, with cozy wood interiors, fireplace and balconies.

domain: travel


text:
The bodies of two British soldiers feared to have been executed have been found in a shallow grave in Iraq, the Ministry of Defence said today.
The remains of Staff Sergeant Simon Cullingworth, 36, and 24-year-old Sapper Luke Allsopp were found near Al Zubayr, outside Basra in Iraq's south.
It is feared their Land Rover was ambushed and the men shot in cold blood after they went missing on March 23 near Al Zubayr. Their bodies were then broadcast on al-Jazeera TV causing outrage in Britain.
An MoD spokeswoman said cause of deaths had not been confirmed but that execution was a possibility, and an investigation was ongoing.
Sapper Allsopp, from north London, and Sgt Cullingworth, from Essex, were both members of the 33 (EOD) Engineer Regiment, a specialist bomb disposal unit of the Royal Engineers.
Last month, a row broke out over the deaths when Prime Minister Tony Blair said that the men had been "executed".
The family of Sapper Allsopp reacted angrily, saying the Army said the men died in combat.
A military source told The Sun newspaper that the discovery of the bodies in a shallow desert grave on the outskirts of Al Zubayr backed up Mr Blair's comments because it was unusual for soldiers who die in battle to be buried by the enemy.
But a MoD spokeswoman would only say: "We can confirm a number of bodies were exhumed from that area. Post mortem tests are now being carried out."
On a visit to the US earlier this month, Mr Blair waded into controversy and drew condemnation from the family of Sapper Allsopp by saying the soldiers had been executed.
He spoke of "the release of those pictures of executed British soldiers" and condemned the decision to broadcast them as "an act of cruelty beyond comprehension".
Although admitting there was not conclusive proof of how the pair died, Mr Blair's official spokesman insisted the Prime Minister had been right to say the two Royal Engineers had been executed.
But Sapper Allsopp's sister Nina, 29, and Iraqi authorities said the claims were "lies".
She told the Daily Mirror that senior officers from her brother's barracks in Wimbish, Essex, informed the family he had been killed instantly in battle.
"It makes a big difference to us knowing he died quickly," she told the newspaper.
"We can't understand why people are lying about what happened.
"It's important to us that people know the truth."
Following Mr Blair's comments, armed forces minister Adam Ingram expressed "regret" for any distress caused, but maintained: "Given the information available to us, it did indicate those two soldiers may have been executed."


text:
BioCare Femforte II (Multi-Formula For Women)
Femforte® II has been formulated as a comprehensive, low dose Multivitamin & Mineral
Complex particularly for the special needs of women, and is particularly high in vitamin E,
magnesium, bioflavanoids, vitamin B3 and vitamin B5.
Femforte® II provides an encapsulated alternative to Femforte® I.
An ideal combination of vitamins and minerals in the correct balance
Provides nutrients in their most bioavailable form for improved absorption
Suitable for women prior to, during and after the menopause
Suitable as a dietary support for women during menstruation
Encapsulated for easier swallowing
Suitable suitable for vegetarian and vegan Ingredients for BioCare Femforte II
Product Information per Daily Intake (2 Capsules)
Vitamin C 450.8mg
Vitamin E 110iu 75mg
Niacin (vitamin B3) 50mg
Citrus Bioflavonoids 50mg
Pantothenic Acid (vitamin B5) 50mg
Choline Bitartrate 30mg
Thiamine (vitamin B1) 20mg
Riboflavin (vitamin B2) 20mg
Para amino benzoic acid (PABA) 12mg
Vitamin B6 10mg
Beta Carotene 4.5mg
Folic Acid 150μg
Vitamin B12 50μg
Vitamin D2 150iu 3.8μg
Vitamin C (as Ascorbic Acid & Magnesium Ascorbate), Magnesium Citrate, Capsule (Hydroxypropyl methylcellulose & Water), Calcium Citrate,Vitamin E (as D-Alpha Tocopheryl Succinate1), Potassium Citrate, Pantothenic Acid (as Calcium Pantothenate), Niacin (as Niacinamide), Citrus Bioflavonoids, Zinc Citrate, Manganese Citrate, Modified Tapioca Starch, Choline Bitartrate, Inositol, Thiamine (as Thiamine Hydrochloride),Riboflavin, Para Amino Benzoic Acid (PABA), Vitamin B6 (as pyridoxal-5-Phosphate), Olive Oil, Bulking Agent (Cellulose), Anti-caking Agent (Vegetable Magnesium Stearate), Beta Carotene, Antioxidants (Natural Mixed Tocopherols1, Ascorbic acid & Ascorbyl Palmitate), Copper Gluconate, Hydroxypropyl methylcellulose, Sodium Molybdate, Chromium Polynicotinate, Folic Acid, Potassium Iodide, Sunflower Oil, Biotin,
Vitamin B12 (as Hydroxycobalamine), Sodium Borate, D-Alpha Tocopherol1, Sodium Selenite, Vitamin D (as Ergocalciferol).
1. From Soya
Two capsules taken daily with food, or as professionally directed.
Long term intake of amounts greater than 4mg of manganese daily may lead to muscle
pain and fatigue.
Combine with MicroCell® Essential Fatty Acids or Mega GLA Complex, and
Bio-Acidophilus for general support. News

domain: chemistry


text:
Active Shooter Forum, Preparedness and Response
8 a.m. to 12 p.m., Thursday, Dec. 5 at the Nacogdoches County Exposition & Civic Center
Featuring: Roundtable discussion with Law Enforcement Officials ▪ Presentations by Jeff Caldwell, Texas School Safety Center ▪ Robert Hurst, Safe to Learn, Lead, Live ▪ Dr. Chris Klingenberg, NMC Health Network
Click and submit questions for discussion. No charge to atend, but registration is requested. Call 936-560-5533 or click here to register online
TEXAS STARTS HERE! Welcome to Nacogdoches, the oldest town in Texas and the official Garden Capital of Texas.
It is in Nacogdoches that you walk in the footprints of history. Texas starts here. For centuries the people who have called these lush forests home cultivated the land and tended gardens that nourished the body and spirit. Our streets are lined with landmarks sacred to Texas history.
Make time to experience the abundant activities in Nacogdoches. Choose from fishing, water skiing, camping and boating fun on Lake Nacogdoches, Lake Naconiche or Sam Rayburn Reservoir. Enjoy any of the 16 city parks, six city tennis courts and a rodeo or concert at the Nacogdoches County Exposition Center.
Nacogdoches is home of the Texas Blueberry Festival. Make plans to attend the festival during the second weekend in June!
Are you in business or ready to start? Here's information on Joining the Chamber.
Click for more Nacogdoches Facts | Sign up for our Email Newsletter | Click to view our Event Photos

domain: geography


text:
Today’s Veterinary Business Staff
Everything a veterinarian should know about properly prescribing and storing opioids and disposing of them has been summarized in a new resource guide published by the U.S. Food and Drug Administration’s Center for Veterinary Medicine.
The online article, available at http://bit.ly/2vMtZlF, is intended to help veterinary professionals “educate themselves about the safe use of opioids,” said FDA Commissioner Scott Gottlieb, M.D.
“We recognize that opioids and other pain medications have a legitimate and important role in treating pain in animals, just as they do for people,” Dr. Gottlieb said. “But just like the opioid medications used in humans, these drugs have potentially serious risks, not just for the animal patients but also because of their potential to lead to addiction, abuse and overdose in humans who may divert them for their own use.”
He noted that the only FDA-approved opioid for use in animals is Recuvyra, a fentanyl product.
Recuvyra is not being marketed by the manufacturer, Dr. Gottlieb said, and “Carfentanil, which is 100 times more potent than fentanyl, is no longer FDA-approved for use in animals after Wildlife Laboratories withdrew the application.”
“Companies are making business decisions about discontinuing the marketing of these products in the context of the current epidemic and with the goal of wanting to avoid the possibility of products being obtained or used illegally,” the FDA commissioner said. “The result is a lack of products that are FDA-approved specifically for use in animals, leaving veterinarians to prescribe products originally approved for use in humans when they determine a need for opioid pain medications for pets.”
The FDA is encouraging veterinarians to use alternative drugs for pain management when appropriate.
“The FDA knows that veterinarians are also on the front lines when it comes to combatting the opioid epidemic that has gripped much of our country, and that keeping opioids secure in the veterinary practice, while retaining access for patient who need pain control, is a primary concern,” said Siobhan DeLancey, RVT, MPH, the Center for Veterinary Medicine’s senior adviser for strategic initiatives.