This mod is not known to work with the latest version of Kerbal Space Program. Proceed with caution.
A config file only mod that creates parts out of FASTCORP Autogarage's Delorean Time machine,Squad's Juno engine and Breaking Ground's Hinge to make a Flying Delorean with transitioning wheels that both drive and hover. Obviously those parts are dependencies for this to work. The Juno type hover engines are optional as the wheel hover jets work well. Due to the way the original wheels were made, you need to turn the first 1 on anticlockwise 90 degrees to be the correct way up to drive, then just clone it for all the others. Prebuilt craft included in the Autogarage folder, just copy it to your save SPH folder. All parts turn up when you type Delorean in the part finder. Allow this to unzip in the Kerbal Space Program folder and allow the Internal config to overwrite the original. This just makes it so they don't wear their helmets when driving. The wheel configs have been upgraded to the 1.12.1 system. Controls for prebuilt that are included in it's craft file.
description = 1,Toggle Car Jet Engine power.3,Toggle Wheels Jet Engine power.5,Toggle car generator to turn liquid fuel to electricity(generally not needed and is thirsty)7,Toggle wheel steering(requires 2 taps to start, used to lock wheels so they don't alter thrust direction when flying, which stuffs up yaw.)9,Toggle hinge power(turn off hinge power when parked to stop electrical drain)10,Toggle hinges from drive to flight.Custom 2,Control throttle of wheel jets. Need 80+ throttle to take off and about 73 to hover. They take time to adjust so change ahead of time and wait till they catch up.
Raw stats are from the beginning of time until now. Each follower and download entry represents one hour of data. Uneventful hours are omitted.


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Arthropoda (Arthropods) is a phylum of Animal. There are 1129477 species of Arthropods, in 107434 genera and 3793 families. It includes groups like Trilobites, Myriapods, and Chelicerates.
EOL has data for 7 attributes, including:
The environments in which many arthropods species are known to live. Select an environment to see its arthropods species checklist.

domain: biology


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The United States is suffering a massive blow thanks to the COVID-19 pandemic. The Centers for Disease Control (CDC) estimate that there are over nine million active COVID-19 cases, with over 230,000 deaths. Governments have rushed to save their populations around the world, putting up new structures to deal with the influx of cases and having their medical staff work around the clock. Yet with all of this, medical systems are becoming bogged down by the sheer force of the outbreak. Amid this backdrop, a surprising savior may come for the medical fraternity in the form of a storage pod.
Storage Pods Being Repurposed as Medical Rooms
USA Today reports that a business founded by US veterans is converting used storage pods into remedial rooms for dealing with the COVID-19 outbreak. The organization states that they’re designing these self-sustained rooms to have everything a regular hospital room needs to have. Additionally, the room comes with its own HVAC system that develops a negative air pressure within the pod, along with visual and auditory warnings that a patient can trigger if they need help.
The pods are retrofitted with fiberglass interiors, making the surface easy to clean. The first six units were met by celebration when delivered by the organization who intends to devote more time and money to these retrofitted, self-contained medical rooms. The units are affordable enough for health facilities to order a few, and they can be produced rapidly, which is vital to handle the massive influx of new cases. Since they’re made out of storage pods, they are incredibly mobile and can be deployed quickly to deal with emergency cases skyrocketing in a locale.
Dealing With a Strained Health System
The number of infections in the US continues to rise, and medical facilities, especially in urban areas, have been taxed. Beds and ICU monitoring rooms are occupied as soon as they become vacated. With the US healthcare system already burdened before the pandemic, these new cases have swamped several emergency rooms worldwide. Construction takes time that these facilities don’t have, and it’s hoped that these storage pod medical rooms will take up the slack. The Washington Post notes that the new wave of coronavirus infections at the tail end of October has trained several health facilities’ resources to handle them. These compact, lightweight, and flexible standalone rooms may be a perfect counter to the looming threat of overcrowding in these medical facilities.
Containers As Buildings Is Nothing New
Storage pods are simply more compact containers. Shipping containers, especially, have seen a rise in popularity as a cheap yet sturdy home construction option. Commercial buildings that have to meet stringent standards for safety don’t have the luxury of using containers for adding on rooms. However, these storage pod facilities may serve a purpose to help ease the massive pressure on the nation’s healthcare facilities. The company that produces them aims to make more to allow for an affordable way to shore up a medical institution’s bed count.

domain: news


Why cyling is great for everyone not just cyclists
Mass cycling could save the NHS £17bn in 20 years, cut 500 road deaths a year and reduce smog, says a new study for British Cycling presented to MPs today
At some point during most discussions about promoting cycling the question crops up: Yeah, but some people dont want to cycle or cant cycle how are bike lanes any use for them?
The answers are many and overwhelming. However, they can be hard to pin down. Luckily, someone has just done just that in a thorough and easy to follow way.
If people in urban England and Wales cycled and walked as much as people in Copenhagen, the NHS could save around £17bn within 20 years.
Shifting 10% of short urban trips from car to cycle, in English and Welsh urban areas outside London, could save over 100 premature deaths annually.
I want to get the message across to children that it is hip and happening to wear high visibility jackets.
Some children think horses are cool, others think that of bikes, so Im trying to show them that its cool to wear bright jackets like the professional men and women do.
Source: Guardian Transport


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Who is concerned ?
ENT surgery is primarily aimed at patients with snoring as well as obstructive sleep apnea syndrome. Several anatomical, morphological and functional abnormalities of the upper aerodigestive tract can prevent airflow from circulating correctly. A complete assessment of the upper airways must be carried out by sleep specialists in collaboration with a multidisciplinary team (ENT surgeon, orthodontist, maxillofacial surgeon). Based on their observations, they will decide on a therapeutic solution by suggesting specific surgical procedures.
The Cenas sleep medicine centre can provide specific surgical procedures in close collaboration with specialists from Hôpital de la Tour :
This procedure consists in removing the patient’s tonsils. It is often recommended for children suffering from sleep apnoea.
Performed under general anaesthetic, this procedure consists in removing the uvula and the lower part of the soft palate.
It is very effective in eliminating snoring in the short and medium term, but has limited success in treating sleep apnea.
Bimaxillary advancement surgery or osteotomy
This surgical procedure is recommended for patients who are intolerant to CPAP treatment and have severe OSA.
It is a major surgical procedure that involves the alteration of the patient’s facial profile. It is the most effective treatment there is for severe OSA.
Hypoglossal nerve neurostimulation
Neurostimulation is the intentional modulation of nervous system activity. It involves implanting a stimulator in the hypoglossal nerve to control the activity of pharyngeal dilator muscles.
It is an effective surgical alternative for OSA, but requires validation by a multidisciplinary committee.
Intolerance and nasal obstruction are limiting factors in the use of CPAP.
Nasal or septoturbinal surgery consists in correcting the nasal septum. It is effective in improving tolerance to CPAP in cases of nasal obstruction, but does not significantly reduce the severity of OSA.

domain: medical


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domain: finance


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Biobehavioral Pain Responses in Former Extremely Low Birth Weight Infants at Four Months' Corrected Age
Objective. To compare biobehavioral responses to acute pain at 4 months' corrected age between former extremely low birth weight (ELBW) infants and term-born controls.
Methodology. Measures of facial behavioral and cardiac autonomic reactivity in 21 former ELBW infants (mean birth weight = 763 g) were compared with term-born infants (n = 24) during baseline, lance, and recovery periods of a finger-lance blood collection. Further, painful procedures experienced during neonatal care were quantified in both groups.
Results. Overall, behavioral and cardiac autonomic responses to the lance were similar between groups. However, the ELBW group seemed to have a less intense parasympathetic withdrawal in the lance period and a more sustained sympathetic response during recovery than the control group. Further, in the recovery period, two behavioral patterns (early recovery and a late recovery) were apparent among the ELBW group.
Conclusions. Biobehavioral pain responses were similar overall between both groups of infants. Subtle differences were observed in cardiac autonomic responses during the lance period and in behavioral recovery among ELBW infants. Whether these findings represent a long-term effect of early pain experience or a developmental lag in pain response remains unclear. The lack of an overall difference runs counter to previously reported findings of reduced behavioral response in former ELBW infants. biobehavioral pain response, premature infants, repetitive pain, heart rate variability.
- NICU =
- neonatal intensive care unit •
- PCA =
- postconceptional age •
- ELBW =
- extremely low birth weight •
- FBW =
- full birth weight •
- CCA =
- corrected chronologic age •
- HR =
- heart rate •
- NFCS =
- Neonatal Facial Coding System •
- ECG =
- electrocardiogram •
- RP =
- respiratory power •
- LF =
- low frequency •
- HF =
- high frequency
Pain experienced at times of neurobiologic vulnerability in premature infants may affect subsequent pain responses.1This observation has raised intriguing questions about the role of early adverse experience influencing neurologic development, and concerns regarding the effects of the care provided in the neonatal intensive care unit (NICU). While in the NICU, preterm neonates seem to have a lower pain threshold than term infants, with further decreases in pain threshold (windup phenomenon) after exposure to painful stimuli.2 ,3 This altered excitability spreads to multiple levels of the spinal cord and may cause nonnoxious stimuli (handling, physical examination, and other nursing procedures) to be perceived as noxious stimuli and stimulate the systemic physiologic responses to stress. This scenario sets up established and long-term responses to tissue injury that outlast the initial noxious stimulus, leading to chronic noxious stimulation (classified as chronic pain or discomfort).4
Altered local tactile and nociceptive responses in preterm infants have been reported. Fitzgerald and colleagues5 compared the development of the cutaneous flexor reflex in preterm infants born at 25 to 34 weeks gestation, and tested at 27 to 39 weeks' postconceptional age (PCA), compared with full-term infants. They found thresholds were lower in infants <29 weeks' PCA compared with full-term newborns, and were equivalent to those of normal full-term infants by 40-week PCA. In infants of 27 to 36 weeks' gestational age, Fitzgerald and colleagues>2demonstrated cutaneous hypersensitivity when flexion reflex was tested in areas of previous tissue damage. Such hypersensitivity is thought to reflect a change in the way afferent nociceptive stimuli are processed in the spinal cord after early nociceptive stimulation.
Increased cardiovascular responses and decreased behavioral responses to blood collection by heel lance were found in 4-week-old neonates born at 28 weeks compared with neonates born at 32 weeks.6Differences in these response patterns were correlated with the total number of invasive procedures experienced since birth, rather than other clinical factors (eg, age, Apgar score, birth weight, severity of illness, or body weight), suggesting pain system immaturity or an altered pain response.
There is also emerging evidence that effects of early pain experience may extend into infancy and perhaps beyond. In a study of the remote effects of circumcision pain in term-born infants, Taddio et al7 reported that circumcised infants had a greater pain response to subsequent immunizations than uncircumcised infants. As well, they reported that among the circumcised group, infants pretreated with eutectic mixture of local anesthetics (Astra Pharmaceutical Products, Inc), subsequent pain response was attenuated. There is indirect evidence suggesting that the effects of early pain extend beyond infancy into childhood in former extremely low birth weight (ELBW) infants. Parent ratings of child sensitivity to everyday pain at 18 months of age showed they regarded their ELBW premature toddlers (birth weight <1000 g) as significantly less sensitive than heavier preterm (1500–2499 g) and full birth weight (FBW) toddlers.8 One quarter of former ELBW (<1001 g) children at age 4.5 years compared with full term children, showed clinically higher ratings of physical complaints of no known medical cause.9 At 8 to 10 years of age former ELBW children rated the pictures of painful events in recreational settings higher than FBW children and emotional response ascribed to the children in the pictures was correlated with time spent in the NICU.10Whereas these studies suggest there may be long-term effects of early pain experience, they have the limitation that they used indirect measures such as parent report or child ratings of pictures.
Previous studies of direct observation of pain reactivity in former ELBW children have been limited to the neonatal period,8 ,9usually at sites of previous injury.2 ,3 To the best of our knowledge there are no published studies which have directly examined pain responses between ELBW compared with FBW children, beyond discharge from the nursery or at a site remote from the site of original repeated injury.11 In the present study, physiologic and behavioral responses to an acute noxious stimulus (finger lance for blood collection) at 4 months' corrected age of former ELBW infants (birth weight <801 g or ≤25 weeks' gestational age) were compared with a cohort of term-born control infants. In particular, we sought to investigate whether pain reactivity (facial behavior and cardiac autonomic responses) would be altered in former ELBW infants receiving a noxious stimulus at a site distal (the finger) to the site of original repeated injury (the heel). We hypothesized that extreme preterm birth, and NICU care, would result in a reduced global/generalized pain response at 4 months' corrected age when compared with the response of term-born control infants.
With approval from the University of British Columbia Clinical Research Committee, British Columbia's Children's Hospital, and British Columbia Women's Hospital Scientific Review Committees, and written informed parent consent, a consecutive cohort of 24 former ELBW infants (mean birth weight, ≤800 g) were recruited from the NICU at British Columbia's Children's Hospital and studied at 4 months' corrected chronologic age (CCA). Criteria for inclusion of the ELBW infants in the study was birth weight <801 g or ≤25 weeks' gestational age at birth, appropriate-for-gestational age, absence of periventricular leukomalacia,>or 2 grade intraventricular hemorrhage, no history of maternal drug abuse. During the study period 71 infants were eligible for recruitment, however, 9 moved and 37 parents refused blood collection for study purposes. The remaining 4 infants were excluded because of technical reasons. A control group of term-born healthy infants (n = 21) were recruited after delivery at British Columbia Women's Hospital and studied at 4 months of age. None of the term-born infants was receiving any medication, had neurologic, cardiac, or respiratory problems, or had a history of prolonged exposure to pain (Table 1).
The study was conducted in a specially designed room in the Biobehavioral Research Unit in the Center for Community Child Health Research for videotaping, physiologic data recording facilities. Infants underwent a finger lance for blood collection (0.5 mL) for a concurrent study of iron metabolism among former ELBW infants. The infant was seated on his/her mother's lap and connected to the Respitrace monitor (Wims, Miami, FL). Recording began when the infant was in an awake, alert, noncry state.12 Blood was drawn from a lance of the middle finger by 1 of 3 lab technicians. Each of the lab technicians conducted blood collection on equal proportions of ELBW and control infants.
To identify biobehavioral markers of an altered pain response, we used measures of facial reactivity13 and cardiac autonomic responses.14 Time segments for data analysis were selected by a priori criteria suitable for the nature of the measures. Videotape and autonomic recordings were conducted simultaneously throughout the study. Facial activity changes very quickly to ongoing events in infants,15 thus 20-second time periods were used for each event. In contrast, analysis of heart rate (HR) variability requires relatively prolonged periods of stability, without movement artifacts, thus time segments of 2.2 minutes per event were used.
Behavioral Data Acquisition
A camera technician conducted video recording. The Neonatal Facial Coding System (NFCS) was used to provide detailed facial activity. The NFCS13 ,16 is an objective, reliable behavioral measure of acute infant pain that has recently been validated for use up to the age of 18 months.17 NFCS trained coders, blind to the subject group and all information about the infants, coded the presence or absence of a discrete set of precisely defined facial actions, using slow motion and stop-frame playback technique. From the NFCS, 7 facial actions were coded (brow bulge, eye squeeze, nasolabial furrow, open mouth, vertical mouth stretch, horizontal mouth stretch, taut tongue), as they have been related to pain in full-term healthy neonates,13 ,18premature neonates,19 ,20 and in infants up to the age of 18 months.17 The data for 1 ELBW infant were missing for the recovery event, because the face was not clearly in view. The infant's scores were replaced with the mean value for that cell, ie, the mean for ELBW infants during the recovery event.
The first 20 seconds from each of 3 events (baseline, lance, recovery) were coded in random order. One coder conducted the main NFCS coding, with 11 (24%) of the infants scored independently for inter-rater reliability. Reliability was calculated according to the formula described elsewhere13 that assesses the proportion of agreement on actions occurred recorded by 2 coders relative to the total number of actions coded as occurring. The reliability coefficient was 0.86.
Physiologic Signal Acquisition
Three standard surface chest electrodes were used to record continuous electrocardiogram (ECG), and a 2-belt microprocessor-controlled inductance plethysmograph system was used to acquire a respiratory signal (Respiratrace-Plus, NonInvasive Monitoring Systems, Miami FL). Both signals were digitally sampled to disk at 360 Hz using a personal computer-based data acquisition system.21 Calibration of the respiratory signal was performed using a previously described algorithm,22 assuming an infant tidal volume of 7 mL/kg. Respiratory volumes were normalized to a standard body surface area of 1.73 m2 to enable comparisons between previous adult and infant respiratory data.23 ,24 One lead of surface ECG and respiratory activity were recorded continuously during baseline, lance, and recovery periods.
R waves were detected from the sampled ECG and used to form a smoothed instantaneous 4-Hz HR time series.25 The inductance respiratory signal (RP) was digitally low-pass filtered and decimated to 4 Hz. Segments of HR and respiratory activity (2.2 minutes each) were selected from: 1) the resting baseline period within 5 minutes before the lance, 2) a lance period starting within 20 seconds after the finger prick blood collection, and 3) a recovery period within 7 minutes after the lance. The epoch duration of 2.2 minutes was based on the need for stable behavioral state and the absence of gross movement artifact as previously reported.23 ,24
Power spectral estimates of HR were quantified using the area (power) of the spectrum in a low-frequency (LF) region (LF, 0.04–0.15 Hz) and a high-frequency (HF) region (HF, 0.15–0.80 Hz), as well as by the ratio of LF and HF power (LF/HF), as previously described.26 Similar measures of respiratory activity were tabulated from the RP spectrum to yield total RP (LF-RP and HF-RP).
To determine the contribution of both sympathetic and parasympathetic components to HR modulation, the effect of respiratory activity on HR was assessed using transfer function analysis, as previously reported in infants23 ,24 and adults.26 Autospectra of the HR and respiratory signals and the cross spectrum between them were estimated for each 2.2-minute (512 point) segment as previously described.27 The complex transfer function, or frequency response, between respiratory activity and HR was quantified using the cross-spectral method to yield magnitude (gain) and phase components. A squared coherence spectrum was also computed to define the degree of the linear relation between respiratory activity and HR. The coherence varied between 0 and 1.
Quantitative measures of cardiac parasympathetic and sympathetic cardiac control were derived from the average coherence weighted transfer gains of the 2.2-minute segments of data. Using this technique, previous work during pharmacologic treatment of adults with either atropine while upright, or propranolol while supine, demonstrated transfer gain and phase plots characteristic of pure parasympathetic and pure sympathetic modulation of HR, respectively.26 A pure sympathetic HR response (during standing with atropine) was characterized by a reduced gain at frequencies 0.01 Hz and a phase delay. In contrast, under pure vagal conditions (supine plus propranolol), the HR responses were characterized by higher gain at all frequencies and no phase delay. From the transfer gain we derived measures of LFtransfer gain (0.04–0.15 Hz) and HFtransfer gain (0.15–0.8 Hz).
The facial data were examined in two ways: 1) a single index of pain for each event was derived from principal components analysis, using a method described previously.17 Repeated measures analysis of variance was conducted on the facial activity pain scores, to examine the role of group (ELBW versus FBW), and event (baseline, lance, recovery). 2) The distributions of individual face actions were examined during each time segment of each event. To examine the pattern of facial response throughout time, occurrence of each of the 7 NFCS facial actions were summed within each 2-second time segment in each event.
The mean and SEM of HR, respiratory activity, and power spectra for each data segment were calculated. A repeated measures analysis of variance was used to compare outcome measures across study periods. To determine the significance of differences of change of a measure, analysis of covariance was used to examine the effect initial or starting measure had on lance response. For the purposes of display, group average transfer function estimates of both gain and phase from each experimental epoch were computed as previously described.26 A difference was considered statistically significant for P < .05. Post hoc comparisons were done where appropriate using Tukey tests.
All infants underwent the finger lance blood collection without complications. Infant and demographic characteristics are presented inTable 1.
NFCS Facial Activity
There were no overall statistical differences in facial pain scores between the ELBW and control groups (f 1,43 = .1, P = .91), or the interaction of group by event (f 2,86 = .97, P = .38). Event was statistically significant (f 2,86 = 170.31, P < .001), and post hoc comparisons showed significantly increased facial activity from baseline to lance, followed by significantly decreased facial activity from lance to recovery (Fig 1).
The distribution of individual NFCS face actions was examined for each group in each 2-second phase period of time in each phase of blood collection. There were no differences between the groups apparent on inspection of the baseline and lance phases. However, during the recovery phase, two patterns emerged for the ELBW infants. During the first 2 seconds of the recovery phase, 43% of the infants in the ELBW group showed no facial activity in the first recovery time segment, suggesting a more rapid return to baseline after termination of the lance procedure. In contrast, only 12% of the control infants' scores were at 0 in time segment 1 (χ2 df 1 = 5.28; P = .05). The mean number of face actions in each time segment is presented graphically for baseline, lance, and recovery phases of blood collection (Fig 2). An overall trend toward less facial activity in the recovery period was evident for the ELBW infants compared with term-born controls.
Mean HR rate increased significantly from baseline to lance period and declined again in recovery periods in both groups (f 2,90 = 111.3, P < .05; Fig 3), however, overall changes with time were not significantly different between groups (f 2,90 = 2.5, P = .08).
Power Spectral Estimates
In both groups, LF and HF power decreased significantly (f 2,90 = 6.7, P = .002 andf 2,90 = 11.8, P < .01, respectively) from baseline, and increased again in the recovery period (Fig 3), however, the differences between ELBW and control groups were not significant. The ratio LF/HF remained stable in both groups across study periods with minimal changes (f 2,90 = .4, P = .7) and no differences between groups (f 2,90 = .327, P = .57; Fig 4). Finally, total RP increased significantly from baseline with the lance and decreased in the recovery period in both groups, (f 2,90 = 110.7, P < .01; Fig 5). Importantly, respiratory spectral power changes were significantly smaller among the ELBW infant group (f 2,90= 6.6, P = .02), particularly at the lance period.
Transfer Function Estimates of Respiratory Sinus Arrhythmia
In both groups the high- and low-frequency transfer gain decreased significantly with the lance and increased in the recovery period (f 1,43 = 116, P < .01 andf 1,3 = 66.4, P < .01, respectively), with no group differences demonstrated (HFTransfer gain and LFTransfer gain in Table 2). Qualitatively, (Fig 6) the transfer gain was high at all frequencies during the baseline period, with the phase beginning near 0 degrees at 0 Hz and decreasing slightly with increasing frequencies, reflecting a predominance of vagal cardiac modulation in the baseline condition in both groups. In response to the lance, transfer gain decreased across all frequencies, and became very low in the HF range. Among control infants it fell to levels below that observed among the ELBW infants during the lance period (P = .01, for differences between group mean HFtransfer gain). The LF transfer gain also decreased, but stopped at levels similar to those in the ELBW group. In contrast to the ELBW group, transfer phase fell more consistently among control infants with increasing frequency, suggesting a greater withdrawal of parasympathetic activity accompanied by increased sympathetic cardiac modulation. In the recovery epoch, transfer gain increased again across all frequencies while phase remained and actually approached 0 degrees at frequencies up to 0.5 Hz, consistent with a return of sympathetic and parasympathetic modulation to near baseline levels. However, in the ELBW group gain increased across all frequencies and phase declined, consistent with a return of parasympathetic modulation as well as a persistent sympathetic response.
In summary, from the transfer function results, both ELBW infants and control infants responded to the lance with increased cardiac sympathetic and reduced cardiac parasympathetic modulation. However, for the ELBW infants there seemed to be less intense parasympathetic withdrawal in the lance phase and a sustained sympathetic response remained in recovery, compared with term-born control infants.
ELBW Subgroup Analysis
Based on the distribution of facial activity during the first 20 seconds of recovery, the ELBW infants were divided into early facial recovery and late facial recovery subgroups. Infant characteristics of the subgroups are summarized in Table 3. Changes in HR and HR spectra were statistically similar between subgroups (Table 4). However, transfer gain and phase changes were qualitatively different between early facial recovery and late facial recovery groups (Fig 7). Overall, the early facial recovery infants seemed to have increased gain at all frequencies, a smaller decline with the lance and increased gain in recovery when compared with the pattern observed in the late facial recovery group. Together these results suggest increased vagal modulation and less sympathetic response among the early recovery group (ie, less responsive to the painful event).
Early recovery infants seemed to be sicker, had longer stays in the NICU, experienced more procedures, and received more intravenous morphine (Table 4). Given the small sample size in each subgroup however, further analysis was not possible to determine the precise association between pain response and previous experience.
In contrast to our original expectation and previous research, the physiologic and behavioral responses among former ELBW infants to an acute noxious event were similar to term-born control infants at 4 months' CCA. In particular, a finger lance resulted in an increase in respiratory-related sympathetic HR control and a significant decrease in respiratory-related parasympathetic control in both groups. However, subtle differences were noted in cardiac autonomic and facial responses. During the lance period, ELBW infants responded with less parasympathetic withdrawal than control infants. Further, the increase in RP that accompanied the lance was significantly less among ELBW infants. Finally, during recovery, the sympathetic response seemed to be more sustained among ELBW infants. Together, these results suggest former ELBW infants seemed less able physiologically to modulate their immediate and recovery response to an acute noxious event. Further, facial reactivity to heel lance did not differ significantly between the ELBW and term-born control infants. However, more ELBW infants (43%) had fully recovered behaviorally as soon as contact by the lab technician was completed, compared with only 12% of the control group. ELBW infants who recovered quickly, as a group, had increased parasympathetic modulation in the baseline period, less parasympathetic withdrawal during the lance, and increased vagal modulation in the recovery period when compared with infants in the late recovery group.
The infants in the ELBW group had been subjected to prolonged periods of neonatal intensive care involving many necessary noxious procedures, leading to our hypothesis that these early experiences would have modified the normal development of pain behavior. Such a modification has been suggested in previous studies of similar children in the neonatal period and at later ages, where this question has been investigated through both parental reporting8 ,9 and the use of responses to pictures.20 The present study, which found only small differences between the ELBW and control infants, is the first to observe ELBW infants undergoing a procedure after discharge from the NICU. The infants in the earlier studies likely received less analgesia in the NICU than current cohorts of ELBW infants because of changes in practice patterns. In addition to the later age of observation, another difference between the Johnston and Stevens6 study at 32 weeks' PCA, and our study at 4 months' CCA, was that the previous study used heel lance, which was a site already used for blood collection during the infants' time in the NICU. In the present study a previously unused site, finger lance, was the location. There are assumptions that repeated pain to one site may lead to widespread alteration in the entire pain system. The reduced parasympathetic withdrawal during the lance and sustained sympathetic activity in the recovery period among ELBW infants seems consistent with the less mature acute pain response reported by Johnston and Stevens6 in preterm neonates studied at 32 postconceptual weeks after 4 weeks in the NICU. However, in the current study, overall differences were minimal at the pain-naı̈ve site. In a study of term-born infants, circumcised boys showed different responses to inoculation at age 4 months, suggesting a generalized alteration of the subsequent pain response. Although it is likely that the ELBW infants in the present study received analgesia in the initial adjustment to the ventilator, subsequently many painful procedures (eg, heel lance blood collection) were conducted on these ELBW infants without pharmacologic pain intervention. Therefore, the present findings are at odds with the effects of a single untreated pain experience as suggested by the observations of Taddio et al.7 The relationship between hyperalgesia at one location and alterations to the systemic pain response after a noxious event at a remote location remains to be determined.
Previous work examining the effects of subsequent pain response in a region of previous repeated early injury2 has demonstrated an altered pain response. The subtle nature of our observations might reflect the robust nature of the developing pain system and the continuing capacity to overcome the effects of early repeated noxious events. In addition, we may have not found an overall altered reaction because we examined the pain response at a site remote (finger) from the area of predominant initial early injury (heel) in ELBW infants. The relationship between hyperalgesia at one location and alterations to the systemic pain response after a noxious event at a remote location remains to be determined (ie, hyperalgesia at one site could represent changes to the peripheral nervous system only, and may not represent any alteration on a global level).
Time frames and gestational ages of infants in previous studies may make direct comparisons between studies difficult. The work of Fitzgerald and colleagues2 examined effects of previous pain/injury throughout hours or days; whereas Johnston and Stevens6 reported on the effects of previous pain that had occurred weeks or even months before. Similarly, Fitzgerald and colleagues2 examined the effect of repeated pain experienced at the same site of original injury; in the study by Johnston and Stevens6 the site was not clear. In the current study we examined response at a pain-naı̈ve site well beyond the time of initial injuries (5 months).
The inference is frequently made that the younger preterm infants are less capable of modulating their pain response.6 It is not clear whether this continues beyond 40 weeks' PCA. Our data suggest that such differences seem to persist beyond term, but are relatively small, and seem unlikely to be of clinical importance for most infants. However, there may be subgroups of infants who have been more affected by their NICU stay than others.
A number of concurrent factors among ELBW infants may also contribute to altered pain reactivity. Neurologically impaired individuals, such as adults with cognitive impairments,28 frail elderly,29 and adolescents with cerebral palsy30 may have blunted acute pain reactions. In this study we sought to avoid these neurologic confounds by excluding infants with a history of clinically significant abnormalities on neonatal head ultrasound (intraventricular hemorrhage >2 and/or absence of periventricular leukomalacia).
The current study suggests some subtle, but perhaps important differences in the global pain response between ELBW and term-born infants that will require future study. Among the ELBW infants during the recovery period 2 behavioral patterns emerged (early-facial and late-facial recovery) which suggest the importance of looking beyond the immediate postlance period. Examination of cardiac autonomic responses in these 2 subgroups also yielded distinct differences in the characteristics of their pain responses. Infants in the early recovery group began with increased parasympathetic modulation in the baseline period, less parasympathetic withdrawal during the lance, and increased vagal modulation in the recovery period when compared with infants in the late recovery group. These differences in autonomic response to the lance may illustrate a lag in maturity of the developing pain system rather than an altered response secondary to early pain experience.
Infants in the early recovery group received more morphine during longer NICU stays. Although the number of infants in this subgroup was small, this observation does raise the possibility that early morphine exposure in ELBW infants may itself influence subsequent pain response. The effects of early analgesia and pain exposure has been recently demonstrated by Rahman and coworkers31 investigating the effects of inflammatory pain and morphine use during the first day of life on subsequent pain response in rats. They found that early pain treated with morphine led to a typical adult opioid analgesic response in adult rats. In contrast, however, morphine given in the absence of pain shifted the opioid dose-response curve in the adult, raising the threshold for its effects. These results suggest that both early pain and opioid exposure have long-term implications in animal models, depending on whether they occur alone or together.
Our data may have implications for our current approach to blood collection in the NICU. Although there are few suitable cutaneous sites for blood collection in the premature neonate, sites should probably be rotated. Further, because there may be long-term and unwanted consequences of early pain exposure, the need for every procedure should be considered, even ones considered routine.
Derived physiologic parameters possibly reflecting pain must be interpreted with care. If HR spectral data are considered alone, the reduction in both LF and HF and the lack of change in their ratio could be interpreted as a pain-related decrease in parasympathetic HR modulation with little or no change in sympathetic activity. This interpretation would be inconsistent with the expected increase in mean HR and sympathetic arousal accompanying a noxious event. However, we also found a significant increase in respiratory signal power. Because LF and HF fluctuations are strongly influenced by both the frequency and amplitude of respiratory activity,32 changes in respiratory activity must be accounted for when interpreting spectral results. When the transfer function between respiration and HR was used to account for the effects of changes in respiratory activity, transfer gain and phase demonstrated that sympathetic HR control increased with the lance, whereas parasympathetic control decreased significantly in both groups. The inclusion of the influence of respiration and the transfer function to account for sympathetic and parasympathetic changes leads to results which are more consistent with both the expected physiologic response.
A number of limitations to the current study need to be mentioned. Given the differences in life experience, many aspects of which may influence patterns of central nervous system development, we should ask whether term infants at 4 months CA are appropriate controls for former low birth weight infants at 4 months' CCA, when in fact they are 7 months ex utero. Detailed work is needed to investigate the neurologic differences between infants of the same PCA but different ages after birth. Second, the biobehavioral measure used is study, although sophisticated, may not have tapped into the same aspects or expression of pain captured by the parent questionnaire in our previous studies,8–10 thereby, presenting 2 plausible but discordant views of an infant's pain response. These differences also require detailed examination. Finally, the current investigation studied pain response at one moment in time and therefore failed to tell us where this response falls into the developmental course among former ELBW infants. In particular, it remains unclear whether the pattern of pain response among the former ELBW infants we observed was indeed a part of a typical course of development of pain reactivity, a temporary pattern or part of a continued developmental lag. Further longitudinal studies are required to address these questions.
Our data are reassuring in that there are few lasting differences in pain response at least at 4 months, despite quantum differences in previous pain experience between ELBW and control infants. This may suggest analgesic use in this cohort has protected the ELBW infants from overt longstanding side effects of repeated pain exposure. But that remains to be seen and at present we do not know what effects early and prolonged opioid exposure have in other developmental domains in infancy or later.
In summary, this is the first study to directly observe ELBW infants undergoing an invasive procedure after discharge from the NICU. Overall behavioral and physiologic reactivity to an acute noxious event were similar between former ELBW and term-born infants at 4 months of age. However, differences in the degree of the parasympathetic reaction during the lance period were found. Further differences in the sympathetic reaction and initial behavioral responses during the recovery period were noted in the ELBW infants. Thus, our data suggest subtle alterations to acute pain reactivity, which were still present 4 months beyond the term period, but were relatively small. Differences apparent to finger lance seemed unlikely to be of clinical importance for most infants. However, because finger lance is a relatively innocuous procedure, the results cannot be generalized to more pervasive pain experiences during childhood. Further, there may be subgroups of ELBW infants who have been more affected by their NICU stay than others. It remains to be determined whether differences in pain responses between ELBW and term-born infants represent a developmental lag inherent to preterm birth, or cumulative effects of early and prolonged pain exposure with varying conditions and amounts of analgesia exposure. The longer-term differences in biobehavioral pain response between ELBW and term-born infants require further study.
- Received February 1, 1999.
- Accepted August 21, 1999.
Reprint requests to (T.F.O.) Biobehavioral Research Unit, Centre for Community Child Health Research, Room L408, British Columbia Children's Hospital, 4480 Oak St, Vancouver, British Columbia V6H 3V4 Canada. E-mail:
- Anand KS,
- Grunau RVE,
- Oberlander TF
- Johnston CC,
- Stevens BJ
- ↵Grunau RVE, Craig KD. Facial activity as a measure of neonatal pain expression. In: Tyler DC, Krane EJ, eds. Advances in Pain Research and Therapy, XV. New York, NY: 1990:147–155
- ↵1996 HR View Software. Boston MA: Boston Medical Technologies
- Oberlander TF,
- Berde CB,
- Lam KH,
- Rappaport LA,
- Saul JP
- Berger RD,
- Akselrod S,
- Gordon D,
- Cohen RJ
- Biersdorff KK
- ↵Rahman W, Fitzgerald M, Aynsley-Green A, Dickenson A. The effects of neonatal exposure to inflammation and/or morphine on neuronal responses and morphine analgesia in adult rats. In: Troels Jensen JA, Turner Z, Wiesenfeld-Hallin Z, eds. Proceedings of the 8th World Congress on Pain. Seattle, WA: ISAP Press; 1997;8:783–794
- Copyright © 2000 American Academy of Pediatrics

domain: health


text:
There’s nothing quite like seeing your drums shining under the stage lights. The gleam of the chrome, the sparkle of the finish and the shine of the cymbals is amazing. Keeping it all looking great however is something you have to work on. There are all kinds of things that threaten the cleanliness of your drums especially if you are out gigging.
Dust and dirt are the common threats but there are a host of other dangers. Spilled drinks, sweat and even blood are all things I’ve had to contend with after gigs. Regardless of what ends up on your drums it’s important to get it off to avoid damage. Your shiny finishes can become dull over time. Chrome can be eaten away by rust and corrosion if left dirty. You also want to keep all those moving parts cleaned and greased to ensure smooth action.
Cleaning your drums is easy but it can be time consuming. Set aside an afternoon at least once a year and do a thorough job. You’ll love how your drums look after cleaning and give you peace of mind knowing you’re protecting your investment. Let’s be honest, drums aren’t cheap.
Step 1: Disassemble & Inspect Your Drums
Clean your drums one at a time and disassemble them completely. You want to get all the dirt out of every nook and cranny. Remove the heads and put all the hardware in a safe place. You’ll be surprised how much junk can build up between the heads and the rims. Once you have the drum torn down you can clean it. It’s also good to do an inspection of your drums at this point. Check for loose or missing hardware. Also check tension lugs for damage to the threads and see if they’re bent. Replace any that are.
Step 2: Clean the Drum
Clean the entire drum with something light like window cleaner or just a damp cloth. Don’t use anything harsh like ammonia, gritty cleaners like Ajax or anything else that’s heavy duty. Drums are like fine furniture and should be treated as such. Clean the outside of the drum with cleaner but avoid using anything on the inside. The interior of a drum is unfinished and any liquids will absorb into the wood. A quick wipe with a clean rag will be enough to get the dust out. Cleaning the drum heads can be done with a simple swipe of cloth. It’s also a good time to inspect heads to see how they’re holding up. If they’re getting worn out replace them now while you’ve got the drums apart.
Step 3 Polishing the Set
After you’ve cleaned the drum you can give it a good polish if you want. A simple, non-abrasive chrome polish will work great on the hardware. Apply a small amount to a rag and work it into every crevice. When you’re done wipe it away with a clean rag and it should shine. Spray furniture polish will work great on the finish of most shells. This will give them some shine and help repel dust in the future.
Step 4: Cleaning the Cymbals
Cleaning cymbals can help keep them shiny and also sounding good. Cymbals are primarily bronze and need some care. A gentle cleaner like dish soap can remove fingerprints and anything else that’s built up on the surface. If you’ve picked up some old cymbals or yours have been neglected then a good polish will do wonders. Be sure to use something that’s intended for bronze or brass. A general polish may harm your cymbals if it’s not formulated for bronze. You can read specifically about how to clean cymbals in that article.
Step 5: Cleaning the Hardware
It’s particularly important to pay special attention to cleaning your drum’s hardware. With all the moving parts you want these kept in good working order. Hi-hat stands and bass pedals deserve special attention. A simple cleaner will be enough to clear away the general grime. Then you can polish up the chrome as you did when cleaning the drums. Disassembling stands is handy to clear away any grime that’s built up where tubes fit together. Doing this will make adjustments easier in the future. When you’re done cleaning use a little bit of lubricant on any moving parts. Stick to a silicone based lubricant rather than petroleum to avoid damage to finishes. If you pick up used hardware that’s had a rough life you might have some rust or corrosion to contend with. Steel wool will quickly remove the spots and help limit it’s ability to spread.
Step 6: Reassembly and Tuning the Drums
When you’ve finished cleaning your drums you can reassemble them and tune them back up. If you’ve never tuned your drums before there are some great guides and videos online. Once that’s done you’re ready to get back to playing.
In-between Cleanings (maintaining your drums)
Full drum cleanings should be done once a year but in the meantime you can do a little upkeep. After gigs, especially those outside, spot clean your drums with a damp cloth. Nasty things like spilled liquids will eat away at finishes if not attended to. It’s tough after a long night but the next day do a quick wipe down on your gear to avoid damage.
Also, despite how expensive they can be, a set of cases is a must. Even soft cases will do wonders at keeping your drums in good condition. I picked up a fantastic set of drums once that were stored in a barn but since they were in good cases they were still in great shape.
Great Products to Clean Drums
Brasso: A great all-purpose metal polish, it will work on your hardware as well as your cymbals. Brasso is highly recommended by many different drummers and you can order it from Amazon.
WD40 Silicone: A great silicone spray for your hardware it will help keep things working smoothly. Use a little on moving parts and other hardware to prevent rust between cleanings. You can find a can of Silicone on Amazon here.
Shop Towels: If it’s been a long time since you’ve done a good cleaning of your drums a big box of shop towels is a must. More durable than paper towels they’ll leave less lint behind and power through grime.

domain: hobby


Jammu & Kashmir Public Service Commission has released Jammu and Kashmir Lecturer Job Recruitment 2018 Apply for 330 J&K Professor Positions at www.jkpsc.nic.in
Jammu and Kashmir Lecturer Recruitment 2018
The J&K PSC Professor Recruitment Advertisement has dispatched by the Jammu & Kashmir Public Service Commission for intelligent and skilled applicants. There are 330 JKPSC Lecturer Vacancies available for vacant positions. Those candidates willing for J&K State Government Jobs they should apply through online mode at the official website i.e. www.jkpsc.nic.in.
J&K PSC Professor Application Form 2018
The Jammu and Kashmir Lecturer Application Form are inviting form skilled candidates through the Jammu & Kashmir Public Service Commission. Applicants who are eagerly waiting for JKPSC recruitment they should read the eligibility criteria mentioned below and apply through online mode in between 19th January 2018 to 21st February 2018.
www.jkpsc.nic.in Lecturer Notification
|Jammu & Kashmir Public Service Commission|
Assistant Professor (Lecturer)
|State Government Jobs|
Jammu and Kashmir
Releasing Date to Apply
|19th January 2018|
|Last Date of Application Form|
21st February 2018
JKPSC Official Website
J&K Public Service Commission Professor Vacancy 2018
|Sr. No.||Position name||Place and College Name||Total Vacancies|
|1.||Assistant Professor (Lecturer)||Government Medical College Baramulla||66 Posts|
|2.||Government Medical College Anantnag||66 Posts|
|3.||Government Medical College Kathua||66 Posts|
|4.||Government Medical College Rajouri||66 Posts|
|5.||Government Medical College Doda||66 Posts|
Jammu and Kashmir Lecturer Recruitment Eligibility Criteria
The officials are inviting applicants to apply for JKPSC Professor Recruitment Exam 2018 via online mode. Those candidates who want get more information of vacant posts they should read the given below details such as required qualification, age limitations, pay scale etc.
- Applicants must age limit in between 18 years to 40 years.
- Also, Age relaxation is applicable to all the reserved candidates.
JKPSC Professor Required Qualification
- All applicants must have Graduation degree from any recognized Board.
- Candidates who are going to apply for 330 JKPSC Lecturer Jobs 2018 they should download the official notice for more details.
- General category candidates have to pay Rs. 800/- + Service Charge Rs. 5/- as application fee.
- Candidates who are related to the reserved category they need to pay Rs. 405/- + Service Charge Rs. 5/- as application fee.
Candidate’s selection process will be totally based on these following methods
- Written Examination
- Personal Interview
JKPSC Lecturer Pay Scale
- Selected candidates will get a salary package of Rs. 15,600/- to Rs. 39,100/- +Grade pay Rs. 6,600/- per month.
- Download the official notification to get more details about vacant positions.
J&K PSC Assistant Professor Recruitment 2018 Apply Online
- Candidate should open the Jammu & Kashmir Public Service Commission official website.
- Download the JKPSC Lecturer Recruitment 2018 official notification and application form.
- Fill the application form and attach all required documentation such as education certificate, I’d card, Photo, etc.
- Before submitting the Jammu and Kashmir Professor Application Form 2018 candidate need to check once again all the details filled are correct.
- Submit the application form and take a printout for future use.
JKPSC Lecturer Recruitment Examination Dates
|Events Name||Crucial Dates|
J&K PSC Assistant Professor Applications Starting On
|19th January 2018|
|J&K PSC Assistant Professor Applications Closed On|
21st February 2018
J&K PSC Assistant Professor Admit Card Releasing Date
|J&K PSC Assistant Professor Examination Date|
J&K PSC Assistant Professor Admit Card 2018
The Jammu & Kashmir Public Service Commission will release the JKPSC Lecturer Hall Ticket 2018 through online mode. Those applicants eagerly willing for J&K State Government Jobs they must subscribe/Bookmark our web page to get more useful information and also visit regularly for checking out what’s new on our page.
JKPSC Official Website: www.jkpsc.nic.in
All Over India Government Jobs
- 1 Jammu and Kashmir Lecturer Recruitment 2018
- 2 J&K PSC Professor Application Form 2018
- 3 www.jkpsc.nic.in Lecturer Notification
- 4 J&K Public Service Commission Professor Vacancy 2018
- 5 Jammu and Kashmir Lecturer Recruitment Eligibility Criteria
- 6 J&K PSC Assistant Professor Recruitment 2018 Apply Online
- 7 JKPSC Lecturer Recruitment Examination Dates
- 8 J&K PSC Assistant Professor Admit Card 2018
- 9 JKPSC Official Website: www.jkpsc.nic.in


text:
PETIT BISCUIT  BEAM
Client Petit Biscuit
Label Petit Biscuit Music
Directors Quentin Deronzier & Scott McPherson
Following the release of his first album, Petit Biscuit asked us to develop a music video based on the cover art concept we designed. We decided to tell his own story: The surreal journey of a young boy trying to find his path.

domain: entertainment


text: The capability of electromagnetic acoustic transducers (EMATs) to detect cracks in stainless steel canisters is described within the context of robot-delivered nondestructive inspection (NDI) of dry storage casks for spent nuclear fuel. NDI of the canister must be performed remotely because of the limited access to the canister, which is enclosed by a concrete and steel overpack structure. Moreover, the environment inside the cask has both elevated temperature and gamma radiation. A potential canister degradation mode that could lead to issues with managing the spent fuel is chloride-induced stress corrosion cracking in the heat affected zone of full-penetration welds. Because access to the outer surface of the canister is limited by guide channels inside the overpack, ultrasonic guided waves are a natural choice for NDI. Shear horizontal (SH) waves sent and received from EMATs aboard a robot are shown to detect flaws in multiple canister mockups.

domain: design


text:
CBS News explains that the new debt ceiling law, among other things,
Creates a 12-person House and Senate special committee to identify further spending cuts. The committee must complete its work by Thanksgiving - November 23 - and Congress must hold an up or down vote on the committee recommendations by December 23. The committee could overhaul the tax code or find savings in benefit programs like Medicaid, Medicare or Social Security. Congress could not modify the committee's recommendation.
Should the special committee deadlock or should Congress reject the committee's recommendations, then automatic across the board spending cuts of at least $1.2 trillion would go into effect.
A National Underwriter article explains how this process may affect health insurers.
The process may have a direct impact on the FEHB Program. The President's deficit reduction commission proposed last year that a premium support approach to the government contribution be tested in the FEHBP. Under premium support, the entire government contribution would be made available to pay the plan premium but the annual increases would be tied to a standard, such as the CPI-U. In other words, an employee or annuitant could have no employee contribution for a low cost plan. Currently, the law, 5 U.S.C. Sec. 8906, provides for a minimum 25% employee contribution. This Kaiser Health News article reviews all of that commision's recommendations.
Health care providers are concerned about the new law. Modern Healthcare notes that
some physician advocates warned about the complicated timing of the work of the deficit reduction panel, which will have to offer $1.5 trillion in cuts by Nov. 23 and secure congressional passage by Dec. 23. That is the same time frame in which Congress will need to find billions of dollars to pay for another delay of the 29.5% cut in Medicare physician reimbursements scheduled for the beginning of 2012.Speaking of Medicare, the Centers for Medicare and Medicaid Services announced today the Program's inpatient hospital care reimbursement policies for the federal fiscal year that begins October 1, 2012
CMS projects that total Medicare operating payments to acute care hospitals for inpatient services occurring in FY 2012 will increase by $1.13 billion, or 1.1 percent, in FY 2012 compared with FY 2011, due to a 1.0 percent increase in payment rates together with other policies adopted in the final rule.
To provide hospitals with an incentive to reduce preventable hospital readmissions and improve care coordination, the Affordable Care Act requires CMS to implement a Hospital Readmissions Reduction Program that will reduce payments beginning in FY 2013 – for discharges on or after Oct. 1, 2012 ‑ to certain hospitals that have excess readmissions for certain selected conditions. Today’s final rule finalizes readmissions measures for three conditions -- acute myocardial infarction (or heart attack), heart failure, and pneumonia – as well as the methodology that will be used to calculate excess readmission rates for these conditions.
The final rule also adopts a Medicare spending per beneficiary measure for both the Hospital IQR Program and the new Hospital Inpatient Value-Based Purchasing (VBP) program required by the Affordable Care Act. The new measure will assess Part A and Part B beneficiary spending during a period of time that spans from three days prior to a hospital admission through 30 days after the patient is discharged. The goal is to encourage hospitals to provide high quality care to Medicare beneficiaries at a lower cost and to promote greater efficiencies across care settings and throughout the entire U.S. health care system.


text:
BOSTON -- The Twin Cities region continues to struggle in terms of creating jobs, according to a pair of reports released Tuesday by the Massachusetts Executive Office of Labor and Workforce Development.
In report the labor-force area that includes Fitchburg, Leominster and Gardner was found to have total employment of 47,000 last month, 100 positions fewer than the 47,100 reported for March 2012.
The state's total employment increased by 32,400, or 1 percent, in the past year.
Separately, a second report found that North Central Massachusetts had a jobless rate of 9.1 percent, down from 9.7 percent in March 2012 but far greater than the state's March reading of 6.8 percent.
Fitchburg's jobless rate was 10.2 percent last month, with Gardner at 9.5 percent and Leominster at 9.1 percent. But even non-urban areas such as Lunenburg (8.5 percent) and Westminster (8.3 percent) have reported high jobless rates.
All figures are non-seasonally adjusted.
Alan Clayton-Matthews, an economics professor at Northeastern University, said the state has seen much of its job increases in the medical-device sector, but that North Central Massachusetts hasn't benefited as much as other regions.
"Manufacturing employment in medical devices hasn't been that strong in several years," Clayton-Matthews said, noting that the Twin Cities region has been more reliant on manufacturing than other areas.
The second report also found that the Twin Cities region saw its labor force decline by 1,000 in the past year, suggesting that the long-term unemployed had given up their search to find jobs. The labor force is the sum of those who are working and those who are not working but actively looking for a position.
Clayton-Matthews, who spoke earlier this month at the North Central Massachusetts Chamber of Commerce's Economic Forecast breakfast, suggested a better transportation infrastructure may help to draw more people to live in the North Central Massachusetts region, thus pumping up demand for more services and, hence, creating jobs.
"It's a chicken-and-egg problem," he said. "If they can get households to locate in that area it will help employment. Transportation is one factor."
John Merrill, president of Leominster-based Fidelity Bank, said during the breakfast that the results of a survey sponsored by the bank show that while business owners are extremely optimistic about how their enterprises will perform over the next 12 months, they will make only modest hiring increases.
Follow Dan O'Brien on Twitter at dobrien_thesun

domain: geography


Jennifer Lowe's Acoustic Roadtrip (with Dave Berger)
Blending the distinct harmonies of her trademark green electric violin with the amplified rhythms of Dave Berger’s acoustic guitar, Jennifer Lowe transforms some of rock’s greatest hits into “unplugged” instrumental creations that bring a fresh and imaginative twist to acoustic cocktail music. Putting her artistic touch to classics like “Stairway to Heaven,” “Freebird,” and “Hotel California” and channeling the work of artists that range from Pink Floyd and The Who to Elton John and Sheryl Crow, Jennifer Lowe’s Acoustic Roadtrip is a ride down memory lane that promises pleasant surprises around every turn. Email us to check availability.
January 10, 2009 - Milwaukee, WI
I just wanted to send a quick email to let you know that we LOVED Acoustic Road Trip. What a friendly and wonderful duo. They were the perfect start to a night that ended up being exactly as I had hoped it would be. People loved them, and they sounded fabulous. Please pass along my gratitude. I hope to have the occasion to book them again.
— Karen Siemers


text:
Designers do love the unexpected. In a major surprise, the house of Burberry has revealed it will launch a limited edition collection with iconic British designer Vivienne Westwood. It will debut in early December.
FIMA, the Festival International de la Mode en Afrique, and the continent’s largest regular fashion event, is on the move. Plans were revealed to bring the next edition of the fashion and arts festival to Morocco.
Women in Saudi Arabia are gaining more freedoms under a reform spearheaded by Crown Prince Mohammed bin Salman, who wants to transform its cloistered society, with abayas now being made to reflect the change.
Pierre Bergé, the partner of Yves Saint Laurent who passed away last fall, must be turning in his grave. After Yves retired, he spent a decade predicting haute couture's demise. Instead it has rarely looked healthier.
Tommy Now, the multi-media See Now Buy Now runway show developed by Tommy Hilfiger, has a new destination: Shanghai. Where the designer will present a clothes designed in part by Formula One star Lewis Hamilton.
First you see his runway shows; then you shop his collections for Chanel, Fendi and his own Karl Lagerfeld; now you can acquire the designer's former villa in his hometown of Hamburg. Its sticker price is €10 million.


text:
The San Francisco International Airport (SFO) was named as the winner of the San Francisco Chamber of Commerce’s annual Excellence in Business Awards, known as “Ebbies.” The Airport was honored with the Kaiser Permanente Economic Development Award for job creation in the area.
“SFO is a powerful economic engine for the region, supporting over 150,000 jobs related to airport activities,” said Airport Direction John L. Martin. “We are proud to be recognized by the San Francisco Chamber of Commerce for our contribution to local economies.”
The Kaiser Permanente Economic Development Award recognizes companies or organizations that substantially contribute to the economic vitality of San Francisco. Awards were presented on October 3, 2013 at a San Francisco Chamber of Commerce event celebrating the Bay Area’s visionary entrepreneurs, business leaders and exemplary corporate citizens. Approximately 900 business and community leaders were in attendance.
SFO recently released the results of a study into the Airport’s economic impact in 2012, demonstrating that SFO directly accounted for $5.4 billion in business activity supporting 33,580 jobs at the airport. When off-site business activities directly dependent on Airport services are included, SFO contributed $31.2 billion in business sales with 153,000 jobs.
In May 2013, SFO unveiled a Capital Improvement Plan, which is expected to generate an additional 36,000 new jobs over the next 10 years.


text:
According to the Alzheimer’s Association, nearly 5.8 million Americans are currently living with Alzheimer’s disease. By 2050, that number is expected to rise to 14 million.
Detecting symptoms of Alzheimer’s disease as early as possible can be critical to provide appropriate care and avoid potentially dangerous situations. And family and friends can play a vital role in recognizing and calling attention to these changes in behavior, especially for older adults who live alone. While celebrating with loved ones this holiday season, Home Instead Senior Care encourages everyone to become more familiar with the symptoms of Alzheimer’s, to be more aware so that critical warning signs are not overlooked.
Although many are aware that Alzheimer’s disease affects a person’s memory, there are several other lesser-known indicators that commonly go unnoticed such as notable changes in mood or personality, difficulty completing familiar tasks, trouble pronouncing words or writing, and increased anxiety.
Lakelyn Hogan, Home Instead Senior Care gerontologist and caregiver advocate, says, “People get wrapped up in the holidays and can miss important signs that a family member needs help – and doesn’t even know it.” She asks families to be mindful of the following signs that a loved one is struggling:
Disruption of daily life. Is your loved one easily confused by changes to his or her routine? Are they beginning to forget everyday tasks, such as taking medication, feeding a pet or paying bills?* Unusual behaviors. Have you noticed they seem unusually agitated or upset? Does it seem like his or her personality has shifted? Do they seem depressed or down?
Disengaged with family. Is your loved one having a hard time remembering names of familiar family members? Does it look as if his or her mind is going blank during conversations? Are they having trouble keeping up with topics of discussion?
Impairments in mobility and judgement. Do they seem afraid or unsure when using stairs? Do they hesitate before taking steps or going down ramps? A decline in cognitive ability can also affect the senses, impairing depth perception and hearing.
Loss of words. Does it seem they are forgetting words for everyday objects, such as toothbrushes, spoons or cups? Are they slow to form sentences or respond to questions?”It’s important that we walk alongside our love ones in the aging process to ensure they are living safe and healthy lives,” explains Hogan. “This holiday season, consider the signs that may indicate early-onset or developed Alzheimer’s disease and talk to your senior relative or their caregiver about ways to accommodate their symptoms.
For additional tips and resources on spotting the signs of Alzheimer’s, go to www.HelpforAlzheimersFamilies.com or, contact your local Home Instead Senior Care office or www.homeinstead.com. (NewsUSA)

domain: psychology


text:
Paul Merton, one of the UK’s best-loved performers, and his world renowned Impro Chums: Mike McShane, Lee Simpson, Richard Vranch and Suki Webster will create a new and unique comedy show, based entirely on suggestions from the audience, their own finely honed improvisational skills and an almost manic compulsion to show off.
Dates & Times
You could see this every night and never tire of it…they continue to be the finest components of the improv art.
Merton’s chums are some of the most seasoned performers in this field and know just how to work the games, the suggestions and the audience for maximum effect. …pure hilarity.
Few can go comedy commando as well as this bunch.

domain: artistic


If you look at the component, you won't believe that the gas cap in your Chevrolet Biscayne is vital-though it is, because it protects the gasoline utilized by your car motor to yield horsepower. Leaking and problems caused by dirt are sure to take place if you do not provide your automobile with a high-quality Chevrolet Biscayne gas cap.
Selecting a gas cap must be done with care-always choose the correct component for your vehicle in order to avert contaminating your gas, paying extra money on fuel refill, and contributing to pollution. Likewise, tighten your Chevrolet Biscayne gas cap correctly to ensure that gasoline vapors are not going to seep out; see to it that the part is firm and not moving in its mounting spot once it's mounted. Another idea is to utilize the said cap as a means to have an enhanced look in your car; just opt for a smart item from the numerous gas caps offered today.
You'll find various parts in the market these days, and amongst the reliable providers that you could count on is Parts Train-we feature more than 1 million parts in stock, available for delivery to your home. Our caps are supplied by top Chevrolet Biscayne gas cap makers including Gates, Crown, plus Brazil, and you can find the said components without any problem.
Use our Part Fit Checker to view parts compatible with your vehicle.


text:
Assembly games allow children to learn crafts from an early age. Creative hobbies have a positive impact on their creative development. They immerse themselves in the world of the imagination where shapes and colors play a role in their ability to concentrate. The wooden gigantic stegosaurus dinosaur kit engages children in imaginary play, which provides important educational benefits for intellectual and social development. There are numbers printed on each part, you need to match the number pair like 1&1, 2&2, and so on to complete the figure. This kit is uniquely designed for young mins to learn balancing of an object. Its perfect resemblance with stegosaurus lets kids enjoy building it from fibreboard pieces. These pieces can also be painted as an added activity that would ignite their creativity and imagination and also encourage your child to invent great stories while understanding in better sense.
During pretend play, children use symbolic representations for the objects and actions they are exploring. When children role-play and explore dialogue it helps them develop social, emotional, and intellectual skills. It helps children acquire confidence and a sense of self which is also a key component of learning. DIY kits have become a well-loved addition and continue to delight children of all ages, both boys and girls.
This wonderfully designed DIY Stegosaurus Dinosaur kit includes :-
- It contains 2 boards with 55 cut pieces and glue.
- Comes with a booklet for easy assembling with instruction.