text:
dia mm cr grinding ball mill rod for quartz plant. 2018526&ensp·&enspdia mm cr grinding ball mill rod for quartz plant Grinding Media Balls manufacturer quality Forged . at a low ball load of 20% of the mill volume and a low powder load corresponding to a formal interstitial filling of the void spaces of the ball bed of U=0.5. Get Price. Read More
Powder grinding plant is also called powder making plant, which is often used for mineral material processing in metallurgy, building materials, chemical industry, mine and other sectors. It can be used for processing non flammable and explosive minerals
Common failure analysis of Quartz Grinding Plant. Fault analysis: A problem often occurred in the operation of the Quartz Grinding Plant is that the discharge port does not produce powder or the amount of powder is low, so that the output is low, and the causes of the failure mainly include the following aspects: First, unadjusted Good locker, the seal is not strict, resulting in the powder
Our grinding mills include VM Vertical grinding mill, MTW European grinding mill, T130X Super fine grinding mill, HGM Micro powder grinding mill, TGM Trapezium grinding mill, Hammer mill and Ball mill, which can be used for Processing Limestone, Quartz, Calcite, Gypsum, Dolomite, Barite, Talc, Coal, Calcium Carbonate, Slag, Iron Ore, Gold Ore, etc.
Quartz Processing & Purifiion Plant Description: To get qualified quartz sand/powder, the first aim is to remove the impurities inside the quartz. Specific expertise in geology, chemical analysis and high purity processing are required in order to convert raw mineral quartz into high purity &
Stone Powder Grinding Plant can be seen in this page, Shangahi Clirik Machinery is a professional powder grinding plant manufacturer in China, we can supply many different kind of powder grinding plants for our customers
Quartz Grinding Plant ManufacturerQuartz Grinding Plant. This plant is where grinding of quartz is performed for its further usage in different appliions Quartz is always high on demand in the market as it is a stable mineral resource both physically and chemically Moreover we ensure that only highgrade raw materials and latest technologies
Quartz grinding mill, quartz powder production Quartz grinding plant. Quartz powder grinding equipment consists of ball mill, "Our quartz powder production line can produce the silica micropowder with 120 M,
Due to the coarse grinding to the specified fineness, it is necessary to maintain a certain residence time in the Quartz Stone Powder Small Grinding Machine. If the amount of ore is not reduced in time, the coarsegrained material in the Quartz Stone Powder Small Grinding Machine will accumulate more and more, resulting in "upward belly".
quartz processing plant India. India is the important market for . Each year, lots of clients will order mineral ore crusher machine and grinding mills from used in local quartz processing plant . In 2011, our professional engineers have designed a complete quartz processing plant india client.
Quartz grinding plant is a silica powder making production line. It includes a set of processing machine to produce ground quartz powder. Quartz is a crystallized form of silicon dioxide, also known as silica. According to Wikipedia, quartz is the second most abundant mineral in earth''s continental crust.
grinding quartz crushing. Quartz Stone Powder Grinding Plant Quartz powder is manufactured by using sedimentary rock as a raw material in smallscale industry The main processes and operations carried out are stone crushing grinding sieving screening mixing storing and bagging
quartz crushing plant in india projectaso . quartz crushing plants in india. quartz crushing plants in india. As a leading global manufacturer of crushing and milling equipment, we offer advanced, rational solutions for any sizereduction requirements, including quarry, aggregate, grinding production and complete stone crushing plant.
Second stage: DCrushed quartz is lifted to the hopper by hoist, then transported by feeder. Third stage: Qualified products after the grinding process enter the collector through classifier and pipe. The discharged powder is finished product. Unqualified powder cannot pass
The quartz is then dewatered through a filtration process, dried in either rotary, apron ore spray driers, and prepared for final appliion. Quartz Grinding Process and Mill Selection. quartz is a very useful mineral resource. For many appliions, it first needs to be processed into fine powder.
Quartz Powder Equipment Quartz Grinding Plant. Quartz grinding is an crucial part of quartz processing operation, whether carried out on a large or small scale and in some cases the grinding mill may be the single most costly item for the production operation. A wide range of mills has been developed for particular appliions.
Quartz grinding plant in india czeu quartz powder grinding plant crusher for saleuartz grinding ball mill near morbi 015 ow to use jaw crusher used cement grinding plant price in india et price and support online quartz crushing factories india. Read Mode Sillica Sand Powder Machine Indonesia.
May 25, 2019 · Powerful grinding mill for gypsum, quartz, calcium carbonate, clay, bentonite and etc Welcome click our website for price and details: https://c
Investment In Grinding Plant Quartz Powder Indonesia. Grinding mill machine mineral mill limestone grinding 3500000typ mtw138 grinding mill for heavy calcium in zhejiang china equipment 40 sets of mtw grinding plant jaw crusher material calcium carbonate capacity 3500000typ 9tph mtw138 grinding plant for coal powder production in indonesia
quartz grinding plant manufacturerquartz crushing plant we deal with the plants for grinding quartz lime stone dolomite and rocks of many such minerals as a manufacturer and exporter we are leading the domain by delivering modern dolomite grinding plant,quartz powder crushing grinding plant.
We deal with the plants for grinding Quartz, Lime Stone, Dolomite and rocks of many such minerals. As a manufacturer and exporter, we are leading the domain by delivering modern Dolomite Grinding Plant, Lime Stone Grinding Plant, Quartz Grinding Plant and Quartz Plant. Assembling quality blades, spares, components, motors and many other
Quartz Stone Powder Grinding Plant Quartz powder is manufactured by using sedimentary rock as a raw material in smallscale industry. The main processes and operations carried out are: stone crushing, grinding, sieving, screening, mixing, storing and bagging.
Grinding Machine For Quartz Mineral. quartz crushing and grinding machine for processing plant. quartz micronizing machine by using thread ball mill 91 VSI crusher is the special quartz crushing machine used in quartz crushing plant Grinding Machine Quartz sand processing plant Silica sand The mill feed is a calculation of grinding media
Alibaba offers 1,529 quartz grinder products. About 23% of these are mine mill, 2% are grinding equipment, and 1% are polisher. A wide variety of quartz grinder options are available to you, There are 1,529 quartz grinder suppliers, mainly loed in Asia.
Silica Sand, Quartz Grinding Mill/Grinding Process Plant, Silica, Quartz Powder Making Plant . Ultrafine Grinding Mill Appliion: QBM ultrafine grinding mill is widely used in construciton, mining, building, chemical, metallurgy industry, coal industry, eleltronic power industry and steel industry,etc. The output size is between 80425mesh
Powder grinding plant process introduction: Grinding system composed with jaw crusher, bucket elevator, electromagnetic feeder, grinding unit, blower, analyzer, cyclone powder collectors, bag filters, pipes and electrical cabinet parts. According to customer demand can adopt Raymond mill, YGM high pressure grinding mill,, HGM micro powder
Quartz Grinding Quartz Grinding Suppliers And. Sponsored listing calcium carbonate mill quartz grinding plant manufacturer features of calcium carbonate mill quartz grinding plant manufacturer high efficien cy under the same finished final size and the same motor power the capacity of micro powder grinding mill is twice as much as jet mill mixing grinder and ball mill and energy consumption
China Ultra Fine Quartz Sand Powder Grinding Plant/grinding Machine For Sale, Find Complete Details about China Ultra Fine Quartz Sand Powder Grinding Plant/grinding Machine For Sale,Powder Grinding Plant,Quartz Sand Powder Grinding Plant,Quartz Sand Powder Grinding Machine from Supplier or ManufacturerHenan Xingyang Mining Machinery Manufactory
Powder Grinding Plant Mineral Processing Plant Cement Plant Stone/Sand Crushing Plant HGM grinding machine kaolin and kyanite powder grinder Limestone Micro Powder Grinder maize grinding machine Micro Powder Grinder Machine Quartz Stone Grinding Mill Raymond Mill Machine Superfine Grinding Mill Ball Mill For Mineral copper
Quartz powder making machine,quartz powder grinding process.Quartz sand and quartz powder can be got through the grinding process of quartz stone nsumption, so the price is higher posits throughout north america to produce industrial silica sand.Each unimin plant is a multimillion dollar investment in quality.
Chinese Quartz Grinding Plants. Chinese quartz grinding plants grinding plant china china quartz powder grinding mill manufacturers 2017 high qu get price quartz sand grinding equipment of ball mill machine a grinding quartz ball mill grinds material by rotating a cylinder with steel grinding.
Quartz grinding plant manufacturerquartz crushing plant we deal with the plants for grinding quartz lime stone dolomite and rocks of many such minerals as a
Feldspar Powder Grinding Plant India. is global supplier of crushing, grinding and mining equipment. We developed complete series of quartz stone powder manufacturing plant for sale in India, each type of grinding mills are available with various specifiion and sizes to meet customers'' requirements on maximum productivity at highest availability.
However, since it is not qualified to make HPQ sand, so Prominer helps him to build the plant to produce quartz sand and powder for quartz slab industry. Compared to mineral beneficiation process, the plant is not very complied but mainly crushing, grinding and screening.
Quartz Powder Grinding Plant. Quartz, inorganic mineral, the main ingredient is silica, usually whiteuartz is a very stable mineral resources physically and chemicallyts crystal belongs to oxide trigonal system, that is, low temperature quartz a quartz, a most widely distributed mineral species.
Daswell Quartz Grinding Plant ManufacturerTailored . Ball mill is the most common quartz grinding mill. The media balls inside the ball mill can ground quartz to fine powder. And the fineness can be controlled by the speed of the ball mill, the sizes and quantity of ball media.
Ball Mill For Quartz Sand Power Grinding Plant China 4: Quartz glass grinding plant. Features of quartz sand ball mill / Silica Sand Ball Mill /Quartz Powder Ball Mill. 1) Ball mill is an efficient tool for grinding many materials into fine powder. 2) The ball mill is used to grind many kinds of mine and other materials, or to select the mine.
Quartz Powder Manufacturing Machine Crushing Plant In Mali Mali is an rising African market and a lot of customers need crusher and grinding mill from CME every year Quartz Powder Manufacturing Process ,Quartz Crusher,Quartz Powder Manufacturing Machinery Silica Quartz Powder Processing Silica Quartz Powder Processing In the. Get Price >>

domain: chemistry


Lance bass not gay
Former pop prima Lance vocaliser had whatsoever blunt thing to say close to gun powerfulness in the U. and the American Red crosswise in the aftermath of the good deal shooting in Las Vegas. The star went off on cultural media around his efforts to gift body fluid as a gay man. plan of action that prohibits some gay men from donating blood. Bass, 38, was riled up after the catastrophe once he completed that he could not supply liquid body substance to the victims. “Every time a tragedy corresponding this happens, I get reminded that I can’t gift blood.
Leilaloo. Age: 31. hello!i'm easy going,charming,independent girl from warsaw!if you'll visit my city-i can be your guide;)ask for my terms;*
Lance Bass and Gay Blood Ban: What You Need to Know About Donating Blood After Las Vegas Shooting If You Are Gay or Transgender
But unspecified people on elite group media, like former NSYNC singer travel Bass, have reportable that they are unable to give origin at their topical hospital or line of descent bank because they are gay. record killed 58 and dislocated around 530 people in Las Vegas pass night, blood banks in Nevada experience been flooded with people wishing to donate blood line to supporter the victims. low tweeted Monday: Here is what you indigence to be intimate about about the Food and have Administration’s (FDA) ban on gay blood donation.
Lance Bass: The gay ‘Bachelor’ is ‘Finding Prince Charming’ not Mr. Perfect – Screener
Think about this: location is a contemporaries of TV optical device vital nowadays who design never person noted a time period once reality-show moulding was any inferior comprehensive and diverse than it is today: e'er exploit more than symbolic of the human race or so us, more real. Logo's new series, "Finding Prince Charming," which premieres th (Sept. 8), is a stepping stone from the near entirely straight, albescent humans of Bachelor Nation.
After Las Vegas shooting, Lance Bass slams Red Cross over gay blood donor ban | Fox News


text:
YORK – As of this past week, York entered its 34th year as formally being a Tree City USA.
The Arbor Day Foundation recognized York for its efforts to promote forestry within its city limits.
“York has achieved this status for many decades,” York Parks and Rec Director Cheree Folts told the city council. “Some stipulations are that you have to have a tree board and a parks department, which we do. We spend $2 per capita for forestry and celebrate Arbor Day, which we do. We also continue to be a Tree City USA and there are signs out there that say we do.”
The city also has a record of a municipal tree ordinance defining the local plans and policies for trees, which is also a requirement for the recognition.
The city’s parks and rec department, along with local kids, recently celebrated Arbor Day, which was created back in 1872 when J. Sterling Morton arrived in Nebraska and said, “There are no trees here,” and immediately set to work to remedy that situation.
There are more than 100 Nebraska communities that have been honored for developing and maintaining a community forestry program, as well as for the commitment to the management and enhancement of the community tree resource.
Get local news delivered to your inbox!

domain: sociology


text:
After procrastinating for several months I have finally completed my MintyPi! Unfortunately I had one of the early boards and had some problems but with some wonderful customer service from Helder I recieved the replacement power board I needed to see the screen.
My original desire for the printed parts were to get the multi color ones but decided the clear parts would be more fun to play with as well as making the hole for the heatsink easier to place. Speaking of heatsink I took a heatsink from a motherboard chipset and cut it down to a reasonable size the used some arctic silver5 thermal compound to hold it to the pi.
Overall I'm very happy how it came out. Though wish I didnt have to take it apart to fix it. Ended up breaking my sd card pulling the board out. Though that did give me an opportunity to overclock the pi a little. Running 1050mhz on the core and the recommended overclock on everything else from retro pi's website. Also I put a penny in instead of a speaker just because I thought it looked cool
Show off your completed mintyPi, or post your build logs here!
1 post • Page 1 of 1
Who is online
Users browsing this forum: No registered users and 1 guest

domain: design


The city of Roanoke, Virginia, responded to the unjust termination claims of one of its former employees, who alleged that she was fired from her social working position for possessing a concealed carry permit.
Storm Durham, the former social worker in question, claimed the city fired her for simply possessing a permit to carry concealed weapons — and noted that she wasn’t even carrying a weapon at the time of her termination.
“The actions taken by the City were not based upon the former employee’s right to hold a concealed carry permit for firearms,” Human Resources Director Michele Vineyard reportedly wrote in the memo.
“I want to emphasize that we have no policy or procedure limiting the right of employees to hold concealed carry permits as authorized by the laws of the Commonwealth of Virginia.
Durham eventually said that, in addition to the city allegedly terminating her over the concealed carry permit, other reasons were cited for her firing, including failure to adhere to dress code and failure to maintain workload standards.
Yes not showing that paper until I talk to my lawyer Monday!
— Storm Durham (@chelstorrm) March 11, 2018


text:
Animators create moving images and motion design for film, television, video games and the internet. They can work in hand-drawn or computer generated animation using intricate techniques and strong artistic skill, and often specialise in particular aspects of the art such as character animation or special effects.
Architects plan, design, and oversee the construction of the built environment. They combine creative vision and technical expertise to shape our lives, from the intimate scale of rooms, to shared public spaces, to vital sustainable cities.
Collection managers and registrars care for the art collections of galleries and museums. They create and maintain documentation systems that allow museums to keep track of their collections, and they oversee the physical care of collection artefacts using a specific skill and knowledge base.
Artists create some of the most vital objects in human society. Using their chosen medium, artists express themselves, challenge their audiences, and reflect their culture in important, powerful ways.
Arts administrators are the glue that holds the arts scene together. They facilitate and oversee the everyday operations of arts entities in government and private industry, by managing staff and budget, fundraising, organising festivals and events, and supporting the artists in their field in many other ways.
Arts educators have broad knowledge across multiple art forms, which they draw on to teach the next generation of artists. They can work with everyone from primary school children to post-graduate university students, and they are responsible for guiding new artists’ talents towards success.
Automotive designers work in teams to create and improve the aesthetics and ergonomics of road vehicles. They integrate new technologies and market research in order to produce vehicles that are more aerodynamic, functional, beautiful and easy to use.
Brand managers oversee the consistency and effectiveness of product branding. They are responsible for the tangible elements of branding, like the look and feel of a product, as well as the intangible, like how consumers relate to the product and its brand. They have keen understanding not only of design principles, but of emotional interaction between brand, product and customer.
Building industry regulators are responsible for keeping the construction industry safe. They work with the government to provide a line of communication between the law and those in the industry, making it a safe industry for everyone involved.
Community development officers are the link between local councils and communities. Using their knowledge of design and planning and an attitude of care and social justice, they help create empowered communities with a high quality of life.
Conservators are responsible for preserving and restoring cultural artefacts. They are technically skilled, deeply knowledgeable in their field, and they use advanced technology to examine and maintain the artworks in their care.
Advertising creative directors apply their knowledge of design, layout and artistic principles to the creation of advertisements from drawing board to completion. They oversee copywriters, graphic designers and artists, manage workflow, use a number of design programs, and create effective advertisements through the careful management of their team.
Arts critics provide a conduit between art and the broader community, helping to define the role that art plays in society. Critics draw on deep theoretical and industry knowledge of art to create a conversation that reaches throughout culture.
Curators manage collections of artwork in galleries, museums, cultural events, festivals and shows. They combine criticism, design and organisational skills to bring together artworks into a cohesive whole, creating engaging, educational or thought-provoking ways for the public to interact with art.
Design retail consultants work with retailers to maximise their space’s potential. They draw on skills in interior design, communication, project management and research to change the way consumers experience a retail space for the better.
Draftspeople prepare drawings and plans based on architects’ designs and sketches. Using physical and 3D modelling to create working plans, they provide the vital step between ideas and built reality, bringing visions into the real world.
Exhibition designers create displays, fixtures, and spatial arrangements for exhibitions and commercial events. They use skills in project management, visual and interior design, and industry knowledge to realise their clients’ visions and create exciting and engaging exhibition experiences.
Experience designers work on the cutting edge of brand engagement. They create multi-platform digital experiences that persuade, inform, entertain and engage users. This field is rapidly growing, and the experience designers at work today are shaping the future of digital interaction.
Filmmakers lead and oversee the production of films, using skills in leadership, visual design, and knowledge of the arts. They are responsible for many aspects of the finished film, and are driven, visually-focused, and creative.
Furniture designers use their practical skills and design knowledge to create objects that we use every day of our lives. They can work on an industrial level, designing for large furniture companies, or on a bespoke, small-business level, creating furniture that blends use and art and enriches its environment.
Gallerists are owners or directors of galleries. They use personal collections and the collections of others, as well as their relationships with established and emerging artists, to create profitable and exciting exhibitions in the galleries they oversee.
Arts policy advisors to the government consult with both government and community to foster the creative arts. They argue for allocation of funding to particular arts groups, and assess where more government support is needed in the artistic community.
Graphic designers blend their knowledge of design, typography, animation and digital interfaces to present information in a meaningful and memorable way. They can work in advertising, illustration, web design, typography and a number of other fields, finding creative solutions to solve visual communication problems.
Illustrators work in visual media to create images for everything from children’s books to advertising to government projects. They are flexible, artistically minded, and keen communicators who use their developed artistic talents to create intimate visual experiences.
Industrial designers create beautiful, functional objects. They combine their understanding of materials, manufacturing, and usability with innovation and aesthetics. Some industrial designers are more technical while others are more artistic; all industrial designers have an enquiring, inventive mind, and can express themselves through drawing and making.
Interior architecture professionals design indoor spaces to suit the people who occupy them. Often remodelling or reworking existing buildings, interior architects work with the natural flow of life through space to create fulfilling and efficient environments that benefit those who live and work within them.
Interior designers shape our experience of rooms and built interiors, using colour, functional design, space and furnishings. They have a keen understanding of how people use the spaces in which they live, as well as knowledge of building codes, healthcare regulations and sustainability principles, which they use to create a living environment suited to the needs of their clients.
Lighting designers create light art that complements theatre, film, music and art productions. They combine technical training and deep understanding of design and colour principles to create profound and subtle interactions between light, art, and people.
Multimedia designers integrate two or more types of media, using both artistic and technical skills. They often work in video games and online platforms, combining visual art, animation, graphic design and typography, but they can also work as independent artists creating multimedia installations.
Museum directors oversee, care for and exhibit a museum’s collection. While they are involved in the creation of specific exhibitions, they also work to acquire art and artefacts to add to the museum’s archives, and may specialise in a particular area, like like Roman-era sculpture or 20th century art.
Packaging designers work with product manufacturers and brands to create eye-catching, effective packages. They can work in everything from household goods to food to cosmetics, and use their skill and knowledge of ergonomics, visual design and consumer interaction.
Photographers work in fields as diverse as food, fashion, and wedding photography. Using a combination of trained eye and technical skills, photographers are responsible for capturing some of culture’s most important moments, and often pursue artistic careers, exhibiting their work in galleries.
Product designers are innovators who work with companies to create new products for their customers to use. Combining art, science and technology, they are responsible for the cutting edge of the consumable production market, and respond to the public’s need for creative solutions to life’s problems.
Project managers oversee the construction of a development project from start to finish. They liaise with architects, tradespeople, and their clients to ensure that the building projects they take care of are efficient, timely and cost-effective.
Property developers create new places for people to live and work in, from the ground up.
Working with architects, engineers, urban planners and more, they use their savvy and business acumen to turn old buildings or raw land into private, commercial and public real estate.
Managers of public art projects oversee the creation and installation of public works of art, like sculptures and murals. They source appropriate artists, seek approval from local council, gauge public interest and reception, and work to make public spaces more creative, bright and artistically engaging.
Stage designers work with theatre and film crews to create stage environments that reflect story. Using artistic skills as diverse as scale modelling, painting, illustration, installation and sculpture they produce scenic design to complement and enrich their production.
Sustainable design consultants are experts in green, renewable methods of design and construction. They advise project managers, architects and property developers on how to best incorporate sustainable design features like green walls and energy and water saving measures.
Textile designers create designs for fabric to be used in clothing, interiors and design. Using their knowledge and skills in the production of fabric from fibres and dyes, textile designers create carpets, clothing, towels and rugs that influence fashion and décor trends.
Transport designers solve problems within the transportation industry through innovative design. They address a vehicle’s comfort, sustainability, safety and branding, and work to create better transportation on land, air and sea, using artistic design skills as well as technical skills like surface moulding and manufacturing.
Urban planning consultants come up with creative ways to make the most of public space. They consider a community’s needs for sustainability and safety, the suitability of the land to proposed projects, and how to create built environments to best serve future generations.
Visual merchandisers use their skills in spatial design to create inviting retail spaces, displays, and installations. They work in window staging, floor planning, and visual and sensory design to attract and communicate with customers and support retail businesses.
Web designers create the first user-facing experience of many brands and companies. They are responsible for a website’s visual design, ease of use, consistency and function, and they often use skills in graphic design, coding and illustration.
Art theorists research and write on the theory of art and aesthetics. They affect change both in academia and in the broader cultural landscape, shape the work of future artists by teaching and guiding them, and play an important role in the social understanding of new forms of art.


New decade New music, Beyonce and Lady Gaga have token over the charts this past year. So don’t expect them to slow dowm for the 2010. Beyonce announced at her final concert in London that she would be reconding a new album for next year Beyonce’World reports. Also mega producer Rodney “Darkchild’ Jerkins also hinted on his twitter that he was working on somthing somthing for the super diva. The Beyonce haters and even some fans thinks she should give it a rest. I think Bey has one more album in her before she steps away from the spotlight at for a while.
Pop sensation Lady Gaga said in a recent interview
The Fame Monster really is a new album, so I guess it’s kind of my second album, and then I’ll put out a third album I guess next year.”
GaGa will now join Beyonce, Britney Spears, Christina Aguilera, and many others who are due to drop their next albums in 2010.
Latoya also is putting in more work for another Lp she said
In the next couple of months I’ll be starting on my third solo album.
I always talk about what I’m going through at the time [on my albums]. The Lady Love album was filled with some of the angry records, the confused records, but it also had the sweet “I Need A U’s” and all of those things, so I’ll try and make another gumbo record, just mix it up. Hopefully I’ll be more in love on the next album!
I Need A U was one of the best songs Of this year. We need more of that please. Really excited for next year. It’s going to go so hard yall just don’t know.
Also expect new releases from No Doubt, Janet Jackson, Jennifer Lopez, Ciara ,Cassie, Christina Milan and a lot more.


text:
Learn more about characters, symbols, and themes in all your favorite books with Course Hero's FREE study guides and infographics!
Pretty easy, overall.
I don't like the way English is taught in schools.
Mostly it was about the British, and french literature.
Hours per week:
Advice for students:
Do your reading and use google as a source if you don't understand the novel.

domain: library


text:
The Kindle Paperwhite (8 GB) with a 6.8" Display: A Must-Own for Book Readers and Top Seller on Amazon
Reading has become more accessible and convenient with the rise of e-readers, particularly Amazon's Kindle series. Their high quality devices boast a variety of features designed to make reading an enjoyable experience. The latest addition to their series, the Kindle Paperwhite (8 GB) with 6.8" display, has quickly become one of Amazon's best sellers - making it essential for book lovers everywhere. In this article we'll explain why owning this model is such a must for avid book readers.
The Kindle Paperwhite (8 GB) features an incredible 6.8" display with 300ppi resolution, providing text that's crystal clear and sharp for increased reading pleasure.
The Kindle Paperwhite (8 GB) is waterproof, making it perfect for reading in any environment - be that the beach, by the pool or even in the bathtub without worrying about damage.
Long Battery Life
The Kindle Paperwhite (8 GB) offers an impressive battery life, lasting up to six weeks on a single charge. That means you can read for weeks without needing to recharge your e-reader.
Lightweight and portable
The Kindle Paperwhite (8 GB) is lightweight and portable, making it easy to take with you wherever life takes you. Perfect for traveling or commuting, reading your favorite books on the go has never been simpler!
Large Storage Capacity
The Kindle Paperwhite (8 GB) offers an impressive storage capacity, enabling you to store thousands of books. Now, enjoy access to your entire library on-the-go without having to lug physical books around with you.
Adjustable Front Light
The Kindle Paperwhite (8 GB) offers an adjustable front light that lets you customize the brightness of the display according to ambient light levels. This provides a comfortable reading experience no matter where in the world you are.
The Kindle Paperwhite (8 GB) with a 6.8" display offers exceptional value for money when compared to other e-readers available on the market. It boasts high-quality visuals, waterproof design, long battery life, lightweight and portable design as well as large storage capacity and adjustable front light - all at an incredibly affordable price!
In conclusion, the Kindle Paperwhite (8 GB) with a 6.8" display is an essential item for book readers. Not only does it boast high-quality visuals and waterproof design, but its long battery life, lightweight and portable design, large storage capacity, adjustable front light, and affordability make it the ideal choice - providing everything you need to enjoy comfortable and convenient reading sessions. So don't wait any longer; invest in this must-have e-reader today and begin building your digital library!


text:
On Friday, a steady stream of residents and city workers spoke at the budget committee about the impact of the cuts.
San Francisco Mayor Ed Lee has proposed slashing $900,000 from supportive housing for the homeless. Agencies like the Community Housing Partnership are bracing for layoffs and a reduction in services.
The program says the cuts don't make any sense.
"We cost $9,000 per person, per year to provide housing a platform for stability," said Gail Gilman with the partnership. "The city and the county of San Francisco spends over $20,000 a year when the person is languishing on the street or in shelter."
The proposed cuts would also shut down the child care and after school program that serves hundreds of Tenderloin children.

domain: politics


text:
SOUTH AFRICA – South Africa will have to put in place a solid export programme for its expected record harvest for any hope of restoring the maize price, because at the present price levels it is not profitable for farmers to grow maize, according to Neel Rust, chief operating officer of Laeveld Agrochem.
The latest South African crop estimate indicates that 2 8 million tonnes of maize must be exported before the next planting season in November to ensure that the stock that is carried over to the next season is not too much.
Although that sounds like a lot, a Free State grain trader says it can be done because in six of the last 13 years about 2 million tonnes per year were exported.
According to independent agricultural economist Fanie Brink, the gross production value of this season’s maize crop is totally overrated.
He says the average price of maize lately traded on the local South African Futures Exchange (SAFEX) market is about R2 000 per tonne, compared to an average price of R5 000 per tonne last season.
The main reason for this lower price can be attributed to the much larger maize crop which, according to the third estimate of the Crop Estimate Committee, amounted to 14 5 million tonnes this year compared to 7.8 million tonnes produced last year.
“This means that the gross value of last year’s maize crop was almost R39bn compared with the estimated gross value of about R29bn this year,” says Brink.
“As a result, the maize crop will make a much smaller contribution to the total gross domestic product (GDP), according to which the country’s economic growth rate is measured, contrary to the overall optimistic expectations that the agriculture industry will help to drive the economy in 2017.”
Rust believes that for export to take place, the local maize price first has to move closer to export parity – the price level at which maize can be competitively exported.
At the moment, there is a gap of about $10 (about R135) per tonne between export parity and the price at which local maize is currently traded.
Export parity is not constant and changes primarily in relation to the American maize price and the rand/dollar exchange rate, with the American maize price having the biggest impact on export parity.
According to the Free State grain trader, the current American maize price of about $3.80 per bushel (39 bushels equals 1 tonne) is considerably lower than the last 10-year average price of $4.80.
Rust says the reason for this is that America is currently sitting with its largest surplus in 12 years.
American maize farmers are currently in their planting season which lasts until the end of May, and this is followed by the pollination period which extends to the end of August. Difficult planting and pollination circumstances could bring about an increase in the American maize price, which would be positive for the local maize price.
“If the American maize price rises from its present level of $3.80 per bushel to its 10-year average price of $4.80, a price increase on the local maize price of about R540 per tonne will be realised,” says Rust.
As at 11 May 2017 yellow maize for delivery in July 2017 is currently trading at about R2 003 per tonne.
If the American planting and pollination period goes well, it can mean that the price of American maize may continue to trade at the current low levels for a number of months.
“If the American maize price does not lift its head, and the South African farmer can position himself so that he is not forced to price his maize at harvest time, he may in all likelihood have to wait until the end of the year, which is the beginning of the next local planting season, for a possible significant recovery in the maize price,” says Rust.
The reason for this is that the oversupply of maize will by then most probably be exported or be included in an export contract that has been closed.
Added to this is the expectation that local farmers will plant less in the next planting season because of the current low maize prices. This bodes well for future maize prices.
“All the factors that can have an adverse effect on the South African maize price have already been discounted.
This includes the expected large local harvest, the strengthening of the rand/dollar exchange rate from about R14 to the current level as well as the American maize price which currently is $1 lower than the average 10-year price,” says Rust.
“The only answer for the low local maize price is the export of the current oversupply. If this does not happen, there is a risk that our maize prices may remain at these low levels until the end of 2018.”
May 21, 2017: Fin24

domain: news


The newest generation of computer games place great demands on computer hardware. Millions of objects must be rotated, scaled, and textured. These tasks require a large number of floating point operations and are highly parallel. As such, graphical processing units (GPUs) have evolved into high-performance parallel processors capable of up to 1 trillion floating point operations per second (one TeraFLOP/s). With the release of Nvidia CUDA software this hardware can be harnessed by the programmer to do computationally intensive tasks unrelated to rendering graphics using a convenient and easy to learn programming toolkit.
We have worked to provide user-ready applications which utilize GPU hardware to accelerate scientific computing. Because most data analysis occurs on the user’s desktop computer, which will generally contain a high end GPU, data analysis codes are an obvious target for acceleration. We have produced a code which calculates radial distribution functions (RDF) at a rate 99 times faster than the CPU. At the moment this code is being incorporated into the VMD visualization software package, where it will be freely available and widely distributed.
Furthermore we have implemented the functional forms for the CMM coarse grain model into the HOOMD-blue open source MD software package. HOOMD-blue is written to run MD simulations entirely on the GPU and achieves up to 60x speedup over equivalent MD codes (including its internal CPU reference code). This code is publicly available since the HOOMD-blue 0.8.2 release version. Please see the Images and Movies Gallery page for some application examples.
In addition, we have worked to provide CUDA support in the CP2K direct molecular dynamics software package. At present, up to a 2x speed up can be attained in cases by performing the Fourier transform on the GPU instead of the CPU. Future generations of GPU hardware will allow to accelerate many more parts time critical parts of the CP2K code. This code is available for download from the CP2K cvs repository.
We are also currently participating at an effort from several groups throughout the US to add GPU accelerated compute kernels to the LAMMPS MD code. This effort is particularly targeted to support future massively parallel supercomputer with large numbers of CPUs and integrated GPUs.Contact: Benjamin Levine, David LeBard, Axel Kohlmeyer Go back to research index.
With dual- and quad-core CPUs becoming ubiquitous on desktops and many-core processors just around the corner, there is a large potential to speed up analysis systematically and significantly with comparatively little effort using hardware that is already in place. To this extent we have added OpenMP parallelism to several analysis tools, and particularly contributed several new parallel plugins to and parallelized existing tools in the VMD visualization and analysis software package. These are a spectral density calculator, a Savitzky-Golay sliding window polynomial filter, a multi-threaded version of the internal VMD command for calculation of radial distribution functions, a multi-threaded FFT plugin. For sufficiently large data sets the speed gain here is frequently of the order of a factor of three on a quad-core desktop.
Many-core CPUs also pose a new problem to getting good parallel scaling using MPI parallel scientific software packages on clusters and supercomputers. The increase of compute units in each node significantly increase the demand for communication bandwidth and increase latencies, since all communication needs to be channeled through a single communication device (Infiniband, Myrinet or similar adapter), particularly when MPI_Alltoall() calls are required like in distributed 3d-Fourier transforms. This problem can to a large degree be avoided by implementing multi-level parallelism, e.g. hybrid OpenMP/MPI, into existing software packages. Our group is currently working on implementing such a hybrid parallel scheme into the LAMMPS MD simulation package.Contact: Axel Kohlmeyer Go back to research index.


The Samsung Galaxy A52 is the latest addition to the Galaxy A series. This is the successor to the Galaxy A51 which was one of the best selling devices in the series. The Galaxy A52 was unveiled together with the Galaxy A72 which is available at a much higher price.
Speaking of price, the Samsung Galaxy A52 will be available in Kenya for Ksh 38,999. At this price, it should be competing with some of the best devices from Huawei, OPPO, VIVO, Xiaomi just to name a few.
“Samsung strives to give consumers what they want and need most. That’s why we set out with a vision for the Galaxy A series to democratise Galaxy innovations for everyone,” said Mr. Charles Kimari, Head of Integrated Mobile at Samsung Electronics East Africa who was present at the event. He further went on to add, “The Galaxy A52 and A72 encapsulate the Galaxy brand philosophy with cutting-edge innovations, services and features at a reasonable price.”
Below are some of the key specifications of the Samsung Galaxy A52.
Samsung Galaxy A52 Specifications
|Specs||Samsung Galaxy A52 Specifications|
|Body||Dimensions||159.9 x 75.1 x 8.4 mm|
|SIM||Dual Nano SIM|
|Type||Super AMOLED capacitive touchscreen, 90Hz|
|Resolution||1080 x 2400 pixels|
|Platform||Operating System||Android 11 ; One UI 3.1|
|Chipset||Qualcomm Snapdragon 720G|
|CPU||Octa-core (2×2.3 GHz Kryo 465 Gold & 6×1.8 GHz Kryo 465 Silver)|
|Storage||Internal space||4/6/8 GB RAM, 128/256 GB storage|
|MicroSD card Slot||microSDXC|
|Camera||Rear Facing Camera||Quad 64MP + 12MP + 5MP + 5MP|
|Features||LED flash, HDR, panorama|
|Video Recording||Yes, up to 4K@30fps|
|Front facing camera||32 MP selfie camera|
|Connectivity||Cellular Data||2G, 3G, 4G|
|Sensors||Fingerprint (under display, optical), accelerometer, gyro, proximity, compass|
|Battery||4500 mAh non-removable battery|
|Available colors||Awesome Black, Awesome White, Awesome Violet, Awesome Blue|
As you can see from the specifications above, the Galaxy A52 is a solid smartphone with powerful specifications. It is offered at a good price and should sell quite well. If I was looking for a phone within this price range, I would definitely consider this one.


text:
Health technology reassessment (HTR) is defined as “a structured, evidence-based assessment of the clinical, social, ethical, and economic effects of a technology, currently used in the health care system, to inform the optimal use of that technology in comparison with alternatives.” Health technology assessment (HTA) agencies need to prepare for this emerging field. This Environmental Scan searched for information on HTR processes that have been developed or are being developed by Canadian HTA agencies as well as by eight international HTA agencies. Countries were selected for this investigation largely because of commonalities with the Canadian context. Out of the nine countries (Table 2) that were included in this Environmental Scan, some form of established process to support HTR was identified in four, i.e., UK (NICE); France (HAS), Australia (PBAC and MSAC) and Spain (OSTEBA and AVALIA-T). From these four, only HAS in France conducts a regular review of publicly funded technologies for a potential HTR. HTR-related reviews in the other three countries (UK, Australia, and Spain) take place only when requested by authorities. Processes related to topic identification or prioritization, were identified in all four countries. There was a general lack of details available in the public domain regarding the research process for these HTR related reviews. Of note, for UK, no HTR processes were identified for SMC and SHTG in Scotland. With respect to the other five countries, a formal framework for HTR was also not identified at CADTH (Canada), INESSS (Canada), ICER (US), AHRQ (US), G-BA (Germany), PHARMAC (New Zealand) and FIMEA (Finland). However, in Canada, an example of ad hoc HTR type of review was identified in the form of an Optimal Use project on Self-Monitoring of Blood Glucose (SMBG) completed in 2010 by CADTH. Further, a pilot project to identify and prioritize technologies for HTR was recently conducted in British Columbia.
Health technology reassessment (HTR) is defined as “a structured, evidence-based assessment of the clinical, social, ethical, and economic effects of a technology, currently used in the health care system, to inform the optimal use of that technology in comparison with alternatives.”1-4
The goal of both health technology assessment (HTA) and HTR is to ensure the “optimal use” of health technologies; “optimal” referring to the proposition of value for money of technologies. However, HTA and HTR are considered to be two distinct fields.5 HTA is related to technology adoption, whereas HTR is an ongoing policy-making process to inform technology use throughout its life cycle.4,5 Hence, HTR is concerned with technologies currently in use, and in particular, their scope of use.1,5 While HTR is generally based on principles and methods of HTA, the methodology also has to include the perspective of diverse users and recipients to account for the reality that the technologies being assessed are in current use.5
The goal of HTR is “to improve patient care and system efficiency through a reallocation of resources away from low-value care toward interventions and technologies of a higher value.”1 Experts emphasize that the goals of HTR to optimize the value of care and increase appropriateness is contingent on a holistic process that includes collaboration with diverse stakeholders. HTR is distinct from concepts such as disinvestment, de-adoption and de-implementation (Table 1); (although these may be the results of a HTR).1,4
Table 1: Definitions of Concepts Different From HTR1
The process of completely or partially withdrawing health care resources from currently funded areas that provide little benefit for their cost. Disinvestment can lead to full or partial withdrawal of a technology, contractual variation, restriction, or substitution and employs financial disincentives.
|De-implementation||The process where the use of low-value care is reduced or stopped on a structural basis in a planned process that uses a set of activities, which can include financial disincentives, but also uses other activities such as data feedback, education, and system interventions.|
|De-adoption||The discontinuation or rejection of a clinical practice after it was previously adopted.|
Resource reallocation through HTR is a result of cessation of inefficient or harmful treatments and practices to fund appropriate and new technologies within a fixed budget, rather than rationing or cutting of existing budgets. HTR can result in decreasing, increasing, or maintaining current levels of use, and in rare cases, even completely withdrawing the technology from the system (obsolescence).4
HTR is an emerging field, and some international HTA agencies have established or are currently developing processes for HTR. Even in the absence of a formal or standard HTR process, some HTA agencies have conducted ad hoc HTR for some health technologies. This Environmental Scan explores the HTR processes that have been established by national and international HTA agencies.
The objective of this Environmental Scan is to identify the processes at national and international HTA agencies (Table 2) to conduct the reassessment of existing or currently funded health technologies, including single and multiple technologies, drugs, and medical devices. The Environmental Scan aims to address the following key question:
- What are the processes at national and international HTA agencies to conduct the reassessment of existing and currently funded health technologies (including single and multiple technologies, drugs, and medical devices) including processes related to:
- topic selection
- conduct of research and type of methods used
- type of resources used, either internal or contracted by the HTA agency, to conduct reassessment projects?
Countries listed in Table 2 were selected largely because of commonalities as compared with the Canadian context, including geography and regulatory HTA or reimbursement processes.
Table 2: National and International Health Technology Assessment Agencies
The Environmental Scan is based on limited literature search, as well as consultation with key informants at national and international HTA agencies. Key informants at the HTA agencies were consulted to identify relevant publications or documents; the latter may not necessarily have been available in the public domain. Relevant published literature was identified primarily through a targeted MEDLINE search; Grey literature was retrieved through a focused Internet search. The literature search was limited to English-language documents published between January 01 2008, and October 16 2018. Only citations retrieved before December 1, 2018 were incorporated into the report.
The Environmental Scan presents information on any existing HTR process at the national and international HTA agencies described in Table 2. The scan is focused on HTR that are conducted to inform formulary and reimbursement policies. Reports, guidelines, and evaluation frameworks from HTA organizations located in the countries listed in Table 2 were reviewed to gather the relevant information.
The following sections present the information on the processes at national and international HTA agencies to conduct the reassessment of existing and currently funded health technologies. Results are grouped by countries where these agencies are located.
A formal framework for HTR was not identified at Institut national d’excellence en santé et en services sociaux (INESSS). A formal framework for HTR was also not identified at CADTH, neither in the Common Drug Review (CDR) nor the pan-Canadian Oncology Drug Review (pCODR) programs.
Example of ad hoc HTR
An example of an ad hoc HTR project was identified in the library of reports of CADTH. Indeed, CADTH’s Self-Monitoring of Blood Glucose (SMBG) Optimal Use project, completed in 2010, could be considered as an example of HTR as it led to limiting the use of SMBG in low-value clinical situations, e.g., regular blood glucose testing in patients with type 2 diabetes treated only with oral medications.6 The following process was followed for the SMBG Optimal Use project.
Topic Selection: The topic was selected based on the recommendation of CADTH’s Canadian Optimal Medication Prescribing and Utilization Service (COMPUS) Advisory Committee (CAC) to review the clinical and economic evidence relating to the optimal prescribing and use of SMBG.7
Research Process: The research process included clinical evaluation (systematic reviews); economic evaluation (cost-effectiveness, cost-utility, and cost consequence analyses); current utilization analysis; current practice analysis; identification of practice and knowledge gaps; and identification of barriers to optimal use.7
Output: The clinical and economic evaluations were used by the COMPUS Expert Review Committee (CERC) to generate recommendations for the optimal prescribing and use of SMBG. The recommendations were developed to inform formulary and reimbursement policies, as well as clinical practice. Several knowledge mobilization efforts including development of implementation support tools were made to ensure the appropriate implementation of the recommendation.6,8
Pilot program in British Columbia (prioritization process for HTR)
A model for prioritizing technologies for HTR was piloted by the British Columbia Ministry of Health’s Health Technology Assessment Committee (HTAC). It should be noted that this model only represents the initial step of the HTR process, which is prioritization; it is nonetheless a model of interest. HTAC conducts assessments of new non-drug health technologies (e.g., devices, diagnostics, and/or medical procedures) and the reassessment of technologies already used within the health system.9
Based on this model, a five-step methodological process was developed. First, a list of low-value technologies was compiled based on NICE (UK) “Do Not Do” recommendations (please see Section below on UK for more details), low-value technologies in the Australian Medical Benefits Schedule (MBS), and Choosing Wisely Canada (note: Choosing Wisely Canada is a list-making initiative of low-value clinical practices based on expert consensus exercises related to systematic and non-systematic reviews of the literature). This list included a total of 1,350 low-value technology recommendations. Secondly, the low-value recommendations were reviewed and coded using the appropriate coding systems for the administrative health data. Based on the review, 1,276 low-value technology recommendations were excluded based on factors such as language or qualifiers not identified in administrative data (i.e., clinically nuanced recommendations); technologies not publicly funded within the British Columbia health system (e.g., complementary and alternative treatments); and as they were drug technologies (as drug coverage falls outside the scope of HTAC). The third and fourth steps involved querying administrative data to examine frequencies of use and costs of 74 included low-value technologies. Among these, 47 low-value technologies were observed in at least one of the administrative health databases (i.e., any frequency and cost) between April 1, 2010 and March 31, 2015. This information was used to rank potential candidates for HTR based on high annual budgetary impact; that is, costs greater than $1 million in a fiscal year. Based on this assessment, a total of nine potential candidate technologies were prioritized for HTR; six were used in-hospital (that is, identified in the hospital database) out of which three were concomitantly identified within the physician claims data. The three remaining technologies were identified only in the physicians and laboratory claims data. As the fifth step, clinical experts reviewed the ranked technologies before broad dissemination and stakeholder action.9
Following this same model, a draft list of seven prioritized candidate health technologies was developed for potential HTR within the context of Alberta Health. (Dr. Fiona Clement, Director, Health Technology Assessment Unit, University of Calgary, Calgary, AB: personal communication, 2018 Dec 20).
The UK’s National Institute for Health and Care Excellence (NICE) has three established processes to support HTR; technology appraisal, recommendation reminders, and commissioning guidelines.2,10
Topic Selection or Prioritization Process: NICE applies the same health technology appraisal criteria for both HTA and HTR; additional criteria may also be considered. These include claimed additional benefit to patients, claimed health care system benefits, patient population, disease impact, cost considerations, and sustainability. Further, criteria for HTA prioritization include the consideration of budget impact, existing alternatives, improved patient safety, vulnerable populations, small benefit, and close risk/benefit ratio.10 NICE also developed the Cochrane Quality and Productivity topics; these are based on Cochrane reviews to identify low-value practices that can be reduced (or stopped) to allocated resources for more effective practices. In addition, NICE has clinical practice guidelines to identify candidates for disinvestment.3,10
Research Process: Similar to its HTA projects for investment, NICE applies a rigorous approach to evidence, meaning reliable data from high-quality studies are required to make any decision to reduce or eliminate funding for specific technologies, thus to conduct HTR projects.10 The Technology Appraisal Committee (TAC) makes decisions on disinvestment. Committee members include members from the National Health Service (NHS), patient and caregiver organizations, academia, as well as pharmaceutical and medical device industries. Commentator organizations include the manufacturers of comparator technologies, National Health Service Quality Improvement Scotland, the relevant National Collaborating Centre (a group commissioned by NICE to develop clinical guidelines in areas such as cancer and mental health), and research groups working in the area.10
During the process of guidance development, NICE independent advisory bodies often make “Do Not Do” recommendations; that is, they identify low-value NHS clinical practices that should be discontinued completely or should not be used routinely.3
Output: The recommendation reminders are released monthly and summarize any new recommendations for the use of an existing technology. The “Do Not Do” list, recommendation reminders and Commissioners’ Guidance list all of the health technologies that NICE suggests avoiding or using sparingly.2,3,10
The “Do Not Do” list has been in effect since 2007, and is available in the form of a searchable database. Each “Do Not Do” recommendation includes additional information regarding the intervention, health topic, the guidance it is based on, any related “Do Not Do” recommendation; as well as the health care setting that describes the main clinical environments in which the intervention or investigation may be initiated.3
The commissioning guides are practical guidelines that help NHS commissioners carry-out NICE recommendations; and also include cost models which will allow commissioners to calculate savings and costs associated with a change in service.2 NICE’s HTR activities are considered to be “passive” HTR, that is, it results in recommendation and guidance that clinicians may choose to follow.2,10,11
SMC and SHTG
A standard framework for HTR was not identified at the Scottish Medicines Consortium (SMC) and the Scottish Health Technologies Group (SHTG). SMC has recently introduced a mechanism to fund a technology on an interim basis for medicines that have received conditional marketing authorizations by the European Medicines Agency (EMA); that is, a medicine can be accepted for use subject to ongoing evaluation and reassessment once further evidence is available that has been requested by the medicines regulatory authority the EMA.12 However, this process is beyond the scope of this Environmental Scan, as the technology is not yet fully accepted (funded), and can be considered to be still in the early stages of its life cycle (that is, technology adoption stage). SHTG is currently in the process of redefining its range of HTA procedures and products. The new approach will be published online in early 2019, and will take into consideration opportunities for reassessment of health technologies. (Edward Clifton, Scottish Health Technologies Group — Unit Head, Healthcare Improvement Scotland, Glasgow: personal communication, 2018 Dec 18).
The Transparency Committee (TC) at the Haute Autorité de Santé (HAS), or French National Authority for Health, reassesses the clinical benefit (“service médical rendu” [SMR]) and/or the clinical added benefit (amélioration du service médical rendu [ASMR]) of the product in the following two situations described below (Dr. Anne d’Andon, Chef du service Évaluation des Médicaments, Haute Autorité de Santé, Paris: personal communication, 2018 Dec 18).
Regular HTR of medicinal products available in the pharmacy (outpatient)
Topic Selection Process: France has a mandatory requirement (by law) to reassess the medicinal products listed on the “national health insurance;” that is, medicines available in the pharmacy (outpatient); every five years after the date of the first inscription of the medicine in the list (Dr. Anne d’Andon, Chef du service Évaluation des Médicaments, Haute Autorité de Santé, Paris: personal communication, 2018 Dec 18).
Research Process: Every five years, the TC of HAS assesses the new clinical data available on the medicine; including efficacy and safety data: new clinical trials, observational studies, pharmacovigilance data, safety concerns from EMA such as new assessment by the Pharmacovigilance Risk Assessment Committee (PRAC), the Agence nationale de sécurité du médicament et des produits de santé (ANSM), or the US FDA. The TC also assesses any modifications since the listing of the medicine, related to the place of the medicine in the therapeutic strategy. For example, if a recently assessed new medicine has been granted a high clinical added value as compared with an older one, the new medicine will be recommended as a first-line treatment instead of the old one (Dr. Anne d’Andon, Chef du service Évaluation des Médicaments, Haute Autorité de Santé, Paris: personal communication, 2018 Dec 18).
As such, every five years, the TC assesses the clinical benefit (SMR), which is a recommendation for reimbursement and according to its level, impact the reimbursement rate. (Dr. Anne d’Andon, Chef du service Évaluation des Médicaments, Haute Autorité de Santé, Paris: personal communication, 2018 Dec 18). Of note, there are four reimbursement rates (i.e., one is “not included in the positive list”; the three other rates are 15%, 30%, 65%). These are determined based on the actual benefit level assigned to the drug (i.e., insufficient, mild, moderate, important).13 Accordingly, based on the reassessment, the SMR can be modified every five years. The key objective of this reassessment approach is to determine whether a medicine should still be reimbursed or not. Companies have to submit to HAS a file containing the new clinical data for the reassessment. If major concerns are not identified, the file follows a simplified procedure in order to quickly produce an opinion for the renewal of the reimbursement. For a total of 834 opinions of the TC in 2017, 209 were for the five-year reassessment of the inscription on the list. For 206 among those 209 opinions, the opinion was positive for the renewal of the reimbursement of the product of the same conditions (i.e., the same rate of reimbursement) (Dr. Anne d’Andon, Chef du service Évaluation des Médicaments, Haute Autorité de Santé, Paris: personal communication, 2018 Dec 18).
Ad hoc reassessment requested by the ministry of health, pharmaceutical company, or by HAS.
Topic Selection Process: The TC may reassess every medicinal product at the request of the ministry of health, the pharmaceutical company, or by its (HAS) own volition. The scope of these reassessments is quite large and can concern the SMR, the ASMR (which has an impact on the price of the product) but also the target population, the comparators, and the impact on public health. This reassessment can take place at any moment in the life cycle of the medicine. If the reassessment is conducted by request of the ministry of health or by HAS itself, it can concern only one product or several products (with the same indication and/or belonging to the same therapeutic class). These reassessments have to be justified by new substantial information (Dr. Anne d’Andon, Chef du service Évaluation des Médicaments, Haute Autorité de Santé, Paris: personal communication, 2018 Dec 18).
Given that medicinal products only available at hospital pharmacies (that is, included only in the “hospital list”) do not fall under the mandatory five-year reassessment program (described above), they may instead be reassessed through the ad hoc reassessment mechanism. For example, the ministry of health has requested the reassessment of approximately 30 drugs on the Diagnostic-Related Group (DRG) list to determine whether they should still pay more than the hospital flat rate (Dr. Anne d’Andon, Chef du service Évaluation des Médicaments, Haute Autorité de Santé, Paris: personal communication, 2018 Dec 18).
The TC can also decide to reassess one or several medicines, in case of new substantial clinical data becoming available (for example safety data, new phase III efficacy data, or modification to the therapeutic strategy) (Dr. Anne d’Andon, Chef du service Évaluation des Médicaments, Haute Autorité de Santé, Paris: personal communication, 2018 Dec 18).
In addition, the company can request the TC for a reassessment of one of their products to obtain a better level of reimbursement (that is, at a better clinical benefit level) or a better ASMR (which also impacts the price of the product), based on new data available (Dr. Anne d’Andon, Chef du service Évaluation des Médicaments, Haute Autorité de Santé, Paris: personal communication, 2018 Dec 18).
Research Process: In the context of reassessment on the request of the ministry of health or by the pharmaceutical company or of the TC itself, the company has to submit to HAS a file containing all the clinical data with a justification of the SMR and/or the ASMR, depending of the request. The file follows the same process as a new request for an inscription on the list(s) (Dr. Anne d’Andon, Chef du service Évaluation des Médicaments, Haute Autorité de Santé, Paris: personal communication, 2018 Dec 18).
The final step is the diffusion of an opinion containing the reassessment of the SMR and/or the ASMR (depending of the original request) for the concerned product(s) (Dr. Anne d’Andon, Chef du service Évaluation des Médicaments, Haute Autorité de Santé, Paris: personal communication, 2018 Dec 18).
On a total of 834 opinions of the TC in 2017, 29 concerned a reassessment of the SMR and/or the ASMR (depending of the request). Among these, 11 were requested by a pharmaceutical company and 18 were requested by the ministry of health or HAS, itself) (Dr. Anne d’Andon, Chef du service Évaluation des Médicaments, Haute Autorité de Santé, Paris: personal communication, 2018 Dec 18).
A formal framework for HTR was not identified at the Gemeinsamer Bundesausschuss or Federal Joint Committee (G-BA). In general, G-BA is entitled to reassess established technologies if necessary. G-BA may conduct reassessments to modify the indication when new evidence becomes available; mostly for drugs, and occasionally for medical devices too; however, this rarely happens. G-BA has in the past suspended assessment processes for new or controversial technologies, and has made decision only after new evidence became available (PD. Dr. med.Matthais Perleth, MPH, Federal Joint Committee (G-BA), Berlin: personal communication, 2018 Dec 18). However, such a ‘suspended review’ would not fall under the scope of HTR, as the technology is not yet currently fully funded.
No formal process for HTR was identified in Australia. However, there are examples of ad hoc “delisting” reviews, utilization reviews and systematic post-market approach to monitor medicines throughout its life cycle; all of which can be considered to be a form of the HTR process.14-16
Examples of ad hoc delisting reviews.
In 2015, upon request from the minister, PBAC provided advice regarding delisting specific drugs that are listed on the Pharmaceutical Benefit Scheme (PBS), which are also available for over-the-counter purchase. This process involved consultation with diverse stakeholders such as physicians and consumers. Based on the PBAC review, more than 17 over-the-counter medicines were reported to be delisted from PBS.14,17
Medical Services Advisory Committee
Along with conducting an appraisal of, and providing recommendation on new medical services proposed for public funding, the Medical Services Advisory Committee (MSAC) may also consider amendments and reviews of existing services funded on the Medical Benefits Schedule (MBS) or other programs (for example, blood products or screening programs). Of note, MSAC is an independent non-statutory committee established by the Australian Government Minister for Health. MSAC appraises new medical services proposed for public funding, and provides advice to government on whether a new medical service should be publicly funded (and if so, its circumstances) on an assessment of its comparative safety, clinical effectiveness, cost-effectiveness, and total cost, using the best available evidence.18 These reviews and amendments are referred to MSAC by the minister for health or under Australian Health Ministers’ Advisory Council arrangements.14 No separate method for evaluating existing medical services (than the method used for the appraisal of new medical services) were identified; and no formal ongoing review of medical services once listed, were identified.
Review of PBS listings
The PBAC and the minister can request reviews of medicine use, cost-effectiveness, and other aspects of quality use of medicines of PBS-listed medicines.19 These reviews include post-market reviews, cost-effectiveness reviews, and reviews of the utilization of specific medicines or groups of medicines.
The Drug Utilization Sub-Committee (DUSC) reviews medicines that have been listed in the PBS for 24 months. DUSC selects individual medicines or groups of medicines to be reviewed as well as undertakes ad hoc reviews as requested by the PBAC or the minister. Both sponsors and consumers are engaged in the review process, and are allowed to provide their comments regarding the review; these are submitted as “stakeholder responses.” The report on the utilization of the medicines (DUSC report), stakeholder responses and DUSC minutes are then referred by DUSC to the PBAC for consideration. DUSC may also provide specific advice for PBAC to consider. Based on the DUSC report, PBAC can make a number of different recommendations to the minister, including revising the restriction wording; revising the category of the listing or type of approved prescriber; requesting DUSC to revise the utilization review report, as specified by the PBAC; requesting further consultation; or advising the minister for health that a post-market review is warranted. DUSC reports are published, and are available for public access.16
Post-market reviews are aimed to improve patient safety, and avoid preventable wastage or inappropriate prescribing, among other concerns. Post-market reviews can be initiated at any time, and proceed only after ministerial approval. The main drivers of post-market reviews are recommendations by the PBAC or issues identified through DUSC’s routine monitoring processes (as discussed above). These reviews are initiated when there are concerns related to the quality use of a medicine, cost-effectiveness, clinical effectiveness, higher than predicted utilization, and/or international differences.
A review takes approximately 12 months, but the time frame may vary depending on the complexity of the review. After the ministerial approval of the review, PBAC sets the Terms of Reference for the review, which also has to be approved by the minister. The evidence evaluation may include a literature review, utilization analysis, economic analysis and more. Stakeholders such as consumers organizations, sponsors of the medicine, and other relevant organizations can also participate during the review process; that is, during public consultation on the draft Terms of Reference, the public submission process; a stakeholder forum; and by providing comments on the draft report. A Reference Group is formed for each post-market review to provide independent, expert advice on specific clinical and consumer issues; including advice to PBAC on issues associated with use of the medicine(s) of interest, the medicine(s) place in clinical practice, sources of evidence and data analyses that should be used, the quality and implications of gathered evidence, and issues raised by stakeholder. Based on the review, PBAC may make a range of recommendations including taking no action; making changes to PBS restrictions; taking measures to improve cost-effective use; updating clinical guidelines; and providing education for health professionals or consumers to improve quality use of medicines. PBS related recommendation (such as listing and pricing) is implemented as per PBAC standard process. A complete framework for the post-market review process and information regarding current and completed post-market reviews is available on the PBS website.20,21
A formal framework for HTR was not identified at the Pharmaceutical Management Agency (PHARMAC).
A formal framework for HTR was not identified at the Institute for Clinical and Economic Review (ICER) or the Agency for Healthcare Research and Quality (AHRQ).
The Galician Agency for Health Technology Assessment (AVALIA-T) and the Basque Office for Health Technology Assessment (OSTEBA) have developed guidelines and tools to support HTR in Spain at the regional level. Spain also has regulatory support for HTR at the national level; such as the Royal Decree 1030 which stipulates that HTR should take place when there is evidence of a lack of efficacy, effectiveness, or efficiency or unfavourable risk-benefit; the technology has lost health care interest due to a technological or scientific development or the technology no longer meets current legislation.2,10
In 2010, OSTEBA developed the Guideline for Not Funding Technology (GuNFT) to guide its HTR process. The model divides HTR into the following seven phases: “a) identification, b) validation of applications, c) prioritization (if necessary), d) assessment of applications, e) decision-making, f) development of an action plan and g) diffusion of the decision.”22
Topic Selection and Prioritization: The GuNFT outlines the following criteria that should be met for a technology to undergo HTR: the technology should be used in the centre (hospital, health system) where the HTR is conducted, the technology status is known to the applicant, alternative treatment options are available, and disinvestment does not lead to absence of care. The guideline notes that a prioritization system needs to be established when a high number of technologies need to be assessed. GuNFT refers to the prioritization criteria established by other researchers and organizations. One example is the prioritization criteria set by the guideline on the identification, prioritizing, and evaluation of obsolete technologies. These criteria, developed by AVALIA-T, are related to the population and users of the technology, the balance between risks and benefits of the technology, and the costs, organizational aspects as well as other implications linked to the technologies to be prioritized.22
Research Process: The guideline emphasizes the need for relevant, high-quality scientific studies to aid the decision-making process. The following three fundamental criteria are considered when making the assessment: the centre´s health care services package and strategic objectives of the centre, the balance between the advantages and disadvantages of adopting the proposal, and, the ability of the centre or health care setting to assume the proposal. The guideline provides a detailed questionnaire to facilitate the assessment.22
Output: The results of the HTR process include the possibilities of disinvestment as per the terms proposed, disinvestment not approved, but could take place in future, and disinvestment is not possible. Following the decision, an implementation strategy is developed. This strategy includes informing relevant stakeholders, and monitoring the impact of disinvestment and that of the technology that was implemented as replacement.22
A formal framework for HTR was not identified at the Finnish Medicines Agency (FIMEA).
The method used in this Environmental Scan was pragmatic. As such, there may be some limitations to this report. In particular, findings are based on a limited literature search of publicly available information as well as targeted personal communications to attempt to obtain further information from international HTA agencies. As it was not possible to establish contacts with all international HTA agencies, and that some of these agencies may not post all of their processes online, some relevant information may not have been captured. On the other hand, it was possible to obtain personal communication from several contacts to support statements on unpublished information. As such, this Environmental Scan may provide information that is unavailable in other similar reports.
HTR is an emerging field; some international HTA agencies have nonetheless established processes to support HTR. Out of the nine countries that were included in this Environmental Scan, some form of established process to support HTR was identified in four, i.e., UK (NICE); France (HAS), Australia (PBAC and MSAC), and Spain (OSTEBA and AVALIA-T). From these four, only HAS in France conducts a regular review of publicly funded technologies to form the basis for a potential HTR. HTR related reviews in the other three countries (i.e., UK, Australia, and Spain) take place only when requested by authorities. Processes related to topic identification, or prioritization, were identified in all four countries. There was a general lack of details available in the public domain regarding the research process for these HTR related reviews. Of note, for UK, no HTR processes were identified for SMC and SHTG in Scotland.
With respect to the other five countries included in this Environmental Scan, a formal framework for HTR was not identified at CADTH (Canada), INESSS (Canada), ICER (US), AHRQ (US), G-BA (Germany), PHARMAC (New Zealand) and FIMEA (Finland). However, in Canada, an example of ad hoc HTR type of review was identified in the form of an Optimal Use project on SMBG completed in 2010 by CADTH. Further, a pilot project to identify and prioritize technologies for HTR was recently conducted in British Columbia. The same was proposed in another Canadian province, Alberta. In the absence of a formal HTR process, key informants from international HTA agencies identified other related processes such as “suspended reviews” (G-BA) and “interim funding decisions” (SMC). However, for the purpose of this Environmental Scan, these processes are not considered HTR as decisions are related to technology adoption as opposed to the reassessment of existing and currently funded technologies.
- Esmail R, Hanson H, Holroyd-Leduc J, Niven DJ, Clement F. Knowledge translation and health technology reassessment: identifying synergy. BMC Health Serv Res. 2018;18(1):674.
- Leggett L, Noseworthy TW, Zarrabi M, Lorenzetti D, Sutherland LR, Clement FM. Health technology reassessment of non-drug technologies: current practices. Int J Technol Assess Health Care. 2012;28(3):220-227.
- MacKean G, Noseworthy T, Elshaug AG, et al. Health technology reassessment: the art of the possible. Int J Technol Assess Health Care. 2013;29(4):418-423.
- Soril LJ, MacKean G, Noseworthy TW, Leggett LE, Clement FM. Achieving optimal technology use: A proposed model for health technology reassessment. SAGE Open Med. 2017;5:2050312117704861.
- Noseworthy T, Clement F. Health technology reassessment: scope, methodology, & language. Int J Technol Assess Health Care. 2012;28(3):201-202.
- Self-monitoring of blood glucose. Ottawa: CADTH; 2010: https://cadth.ca/self-monitoring-blood-glucose. Accessed 2018 Nov 10.
- Optimal self-monitoring of blood glucose Ottawa: CADTH; 2009: https://cadth.ca/sites/default/files/pdf/C1109-Project-in-Brief-final-e.pdf. Accessed 2018 Nov 10.
- Systematic review of use of blood glucose test strips for the management of diabetes mellitus Ottawa: CADTH; 2009: https://www.cadth.ca/media/pdf/BGTS_SR_Report_of_Clinical_Outcomes.pdf. Accessed 2018 Nov 10.
- Soril LJJ, Seixas BV, Mitton C, Bryan S, Clement FM. Moving low value care lists into action: prioritizing candidate health technologies for reassessment using administrative data. BMC Health Serv Res. 2018;18(1):640.
- Seo HJ, Park JJ, Lee SH. A systematic review on current status of health technology reassessment: insights for South Korea. Health Res Policy Syst. 2016;14(1):82.
- Mayer J, Nachtnebel A. Disinvesting from Ineffective Technologies: Lessons Learned from Current Programs. Int J Technol Assess Health Care. 2015;31(6):355-362.
- Interim acceptance decision option. Glasgow: Scottish Medicines Consortium; 2018: https://www.scottishmedicines.org.uk/how-we-decide/interim-acceptance-decision-option/. Accessed 2018 Nov 11.
- Pricing & reimbursement of drugs and HTA policies in France. Saint-Denis (FR): National Authority for Health (Haute autorite de sante); 2014: https://www.has-sante.fr/portail/upload/docs/application/pdf/2014-03/pricing_reimbursement_of_drugs_and_hta_policies_in_france.pdf. Accessed 2018 Nov 15.
- McCreanor V. Active disinvestment in low-value care in Australia will improve patient outcomes and reduce waste Deakon ACT: Australian Healthcare and Hospitals Association (AHHA). Deeble Institute; 2017: https://ahha.asn.au/system/files/docs/publications/171004_issues_brief_no_23-_disinvestment_2.pdf. Accessed 2018 Nov 5.
- Post-market reviews of pharmaceutical benefits scheme subsidised medicines. Canberra: Australian Pharmaceutical Benefits Scheme; 2015: http://www.pbs.gov.au/info/reviews/subsidised-medicines-reviews. Accessed 2018 Nov 15.
- Drug utilisation sub-committee review (Section 9.1). Canberra: Australian Pharmaceutical Benefits Scheme: http://www.pbs.gov.au/info/industry/listing/procedure-guidance/9-review-pbs-listings/9-1-dusc-review. Accessed 2018 Nov 15.
- Conifer D. Government to remove paracetamol, aspirin, other common drugs from Pharmaceutical Benefits Scheme. 2015; https://www.abc.net.au/news/2015-11-03/government-to-scrap-paracetamol-from-pbs/6907222. Accessed 2018 Nov 11.
- MSAC Terms of Reference. Canberra: Australian Medical Services Advisory Committee; 2016: http://www.msac.gov.au/internet/msac/publishing.nsf/Content/msac-terms-of-reference. Accessed 2018 Nov 10.
- Review of PBS listings (Section 9). Canberra: Australian Pharmaceutical Benefits Scheme: http://www.pbs.gov.au/info/industry/listing/procedure-guidance/9-review-pbs-listings/9-review-of-pbs-listings. Accessed 2018 Nov 15.
- Pharmaceutical Benefits Scheme post-market reviews : Stakeholder information. Canberra: Australian Pharmaceutical Benefits Scheme: http://www.pbs.gov.au/reviews/subsidised-medicines-reviews-files/post-market-review-framework-10-2014.pdf. Accessed November 10, 2018.
- Reviews. Canberra: Australian Pharmaceutical Benefits Scheme; 2018: http://www.pbs.gov.au/info/browse/reviews. Accessed 2018 Nov 10.
- Ibargoyen-Roteta N, Gutiérrez-Ibarluzea I, Asua J. Report on the development of the GuNFT Guideline. Guideline for not funding existing health technologies in health care systems. Quality plan for the NHS of the MHSP. Vitoria-Gasteiz (ES): Basque Office for Health Technology Assessment (Osteba); 2009: https://www.osakidetza.euskadi.eus/contenidos/informacion/2010_osteba_publicacion/es_def/adjuntos/e_10_11_report_GuNFT.pdf. Accessed 2018 Nov 12.
About this Document
Authors: Sirjana Pant, Michel Boucher, Nina Frey
Cite As: Health Technology Reassessment: An Overview of Canadian and International Processes. Ottawa: CADTH; 2019. (Environmental scan; no. 85).
Disclaimer: The information in this document is intended to help Canadian health care decision-makers, health care professionals, health systems leaders, and policy-makers make well-informed decisions and thereby improve the quality of health care services. While patients and others may access this document, the document is made available for informational purposes only and no representations or warranties are made with respect to its fitness for any particular purpose. The information in this document should not be used as a substitute for professional medical advice or as a substitute for the application of clinical judgment in respect of the care of a particular patient or other professional judgment in any decision-making process. The Canadian Agency for Drugs and Technologies in Health (CADTH) does not endorse any information, drugs, therapies, treatments, products, processes, or services.
While care has been taken to ensure that the information prepared by CADTH in this document is accurate, complete, and up-to-date as at the applicable date the material was first published by CADTH, CADTH does not make any guarantees to that effect. CADTH does not guarantee and is not responsible for the quality, currency, propriety, accuracy, or reasonableness of any statements, information, or conclusions contained in any third-party materials used in preparing this document. The views and opinions of third parties published in this document do not necessarily state or reflect those of CADTH.
CADTH is not responsible for any errors, omissions, injury, loss, or damage arising from or relating to the use (or misuse) of any information, statements, or conclusions contained in or implied by the contents of this document or any of the source materials.
This document may contain links to third-party websites. CADTH does not have control over the content of such sites. Use of third-party sites is governed by the third-party website owners’ own terms and conditions set out for such sites. CADTH does not make any guarantee with respect to any information contained on such third-party sites and CADTH is not responsible for any injury, loss, or damage suffered as a result of using such third-party sites. CADTH has no responsibility for the collection, use, and disclosure of personal information by third-party sites.
Subject to the aforementioned limitations, the views expressed herein are those of CADTH and do not necessarily represent the views of Canada’s federal, provincial, or territorial governments or any third party supplier of information.
This document is prepared and intended for use in the context of the Canadian health care system. The use of this document outside of Canada is done so at the user’s own risk.
This disclaimer and any questions or matters of any nature arising from or relating to the content or use (or misuse) of this document will be governed by and interpreted in accordance with the laws of the Province of Ontario and the laws of Canada applicable therein, and all proceedings shall be subject to the exclusive jurisdiction of the courts of the Province of Ontario, Canada.
The copyright and other intellectual property rights in this document are owned by CADTH and its licensors. These rights are protected by the Canadian Copyright Act and other national and international laws and agreements. Users are permitted to make copies of this document for non-commercial purposes only, provided it is not modified when reproduced and appropriate credit is given to CADTH and its licensors.
About CADTH: CADTH is an independent, not-for-profit organization responsible for providing Canada’s health care decision-makers with objective evidence to help make informed decisions about the optimal use of drugs, medical devices, diagnostics, and procedures in our health care system.
Funding: CADTH receives funding from Canada’s federal, provincial, and territorial governments, with the exception of Quebec.
Contact firstname.lastname@example.org with inquiries about this notice or legal matters relating to CADTH services.

domain: medical


Hurricane Florence has been a disaster on many levels, leaving economic, social, and environmental destruction in its path across the Carolinas. In North Carolina, a locus of global pork production, continued flooding has also led to a livestock death toll in the millions. This week, Lindsey interviews Tom Philpott, former farmer, and current food and ag correspondent for Mother Jones, about the complex future of confinement meat production in the U.S., and the clean up poultry and hog producers face in the storm’s aftermath.
USDA CAFO facts:
Text FARM BILL to 40649 and tell Congress young farmers need a #farmbillnow.


This is an Application Brief and does not contain a detailed Experimental section.
This application brief demonstrates to provide chromatographic method conditions for preparative systems configured with an ACQUITY QDa Detector using the Preparative Chromatography Mix Standard as a system test prior to injecting samples for isolation.
The Preparative Chromatography Mix Standard assesses the suitability of the preparative LC system for isolating target compounds, ensuring proper system setup and column performance before purifying valuable samples.
Compound isolation requires careful chromatographic system preparation to ensure that the instrumentation is properly setup prior to injecting valuable samples. The Preparative Chromatography Mix Standard is specially formulated with an acid, a base, and a neutral compound and can be used daily to evaluate the condition of the column and to benchmark system performance. Changes in column efficiency or collection parameters are apparent and can be addressed before sample loss occurs. In this technology brief, we document the use of this standard mixture in the Waters AutoPurification System configured with an ACQUITY QDa Detector.
The separation shown in the TIC chromatogram in Figure 1 is typical for injections of the prep standard on the XBridge BEH C18 Column. While diphenhydramine, a base, elutes first at about 2.5 minutes, flavone and diclofenac, a neutral compound and an acidic compound, respectively, elute later but with good resolution between them. Different method conditions and column chemistries may change the chromatographic profile, but routine use of the prep standard should show consistent results when the parameters are held constant.
Analysis of the collected fractions, shown in Figure 2, indicates that the isolated compounds are reasonably pure. These results suggest that the chromatographic system is properly set up and is performing as expected, making it acceptable for isolating and purifying compounds. The ACQUITY QDa Detector method parameters are the same at both the analyticaland preparative scales, and are listed in Figure 3.
720005105, July 2014


text:
The rhetoric keeps ramping up surrounding the future of Plum Island at the eastern edge of Long Island. Two years ago, Homeland Security declared that in advance of shuttering the Plum Island Animal Disease Center in 2023, the entire island would be sold to the public. Donald Trump expressed early interest in buying the 843 acres, which could be worth north of $1 billion on the open market.
Proceeds from the sale will help fund Plum Island Animal Disease Center’s replacement: the National Bio- and Agro-Defense Facility, which is set to open in Kansas in 2021.
Considering the federal government’s legal mandate to sell Plum Island in the next 5 to 7 years, it’s no surprise that entrepreneurs, environmentalists, and officials at the local, state, and federal levels have begun angling for an advantage. On September 28, the New York State Assembly’s Committee for Environmental Conservation agreed to lobby for the preservation of the pork chop-shaped island. According to various eco-advocates, potential development threatens wild populations of osprey, bank swallow, and painted turtles as well as dozens of other native species. Read more HERE.

domain: geography


text:
Source:Expanded Universe (Knights Of The Old Republic)/Expanded Universe (The Old Republic)/The Phantom Menace Expanded Universe (The Phantom Menace Concept Art)
The menacing Sith emerge again and again through the centuries, teaching each generation their dark secrets. A thousand years before the Battle of Yavin, Darth Bane brings the Sith Order back from near extinction in his quest to reclaim their glory. His legacy is carried on by Darth Nihilus, who blights whole worlds in his desire to destroy the Jedi. Darth Maul serves a power-hungry Sith Lord who plots the elimination of the Jedi.

domain: entertainment


text:
Kim Kardashian dismisses rumours she is back together with Kanye West
US reality TV star Kim Kardashian has dismissed rumours
she is ‘back together’ with her former husband Kanye West.
Rumours were rife on social media that the
With the Kardashians
star and Kanye West are rekindling their romance.
However, the mother of four took to Instagram on Tuesday and shared intimate
photos with her boyfriend Pete Davidson, seemingly dismissing the speculations of her rekindle with Kanye.
Meanwhile, according to the
!, the former
Saturday Night Live
star is bringing
light to Kim’s life and it seems the lovebirds are only getting more fun and more serious.
Pete Davidson and Kim Kardashian have been dating for several months.


2019 Road Force by Wells Cargo. 7 wide 16' long. 7' tall rear ramp door .Rv style side entry door diamond tread fenders. v front. bonded sides. led lights
2019 Wells Cargo enclosed trailer. 7 wide by 16 long. 6'6" tall. rear ramp. side entry door. v front. tandem axle. flow thru vents. LED lights
2019 Road Force Cargo Trailer. 7 wide. 14' long. 7' tall. V front. radius style side entry door. aluminum wheels. rear ramp door. trailer is side by side
Get a Quote
Please enter your contact information and one of our representatives will get back to you with more information.
Click to Call
Please enter your name and phone number to get calling options.


text:
Realistic 3D Visualizations
Push the boundaries of imagination
At Archidutch, we pride ourselves on crafting cutting-edge realistic 3D visuals that push the boundaries of imagination. Our team of skilled artists and designers employs state-of-the-art technology to bring ideas to life in stunning detail. From lifelike architectural renderings to immersive virtual environments, our commitment to realism is unwavering. Step into a world where reality and imagination seamlessly converge with our captivating and realistic 3D visuals.

domain: artistic