The Israeli military has informed the families of two Palestinians suspected of murdering Israeli student Dvir Sorek last month that it plans to demolish their homes.
On August 7, Nazir Saleh Khalil Atafra, 24, and Qasem Araf Khalil Atafra, 30, are believed to have stabbed to death the 18-year-old Sorek outside of his religious seminary in the West Bank settlement of Migdal Oz.
The two were arrested two days later after a manhunt.
The army said Thursday that the families were also informed they “can request an injunction against the demolition.”
The army’s notice comes exactly a month after Prime Minister Benjamin Netanyahu promised on August 12 that the homes of the two suspects’ families would be demolished in the near future.
On August 11, Israel Defense Forces measured the homes in the Palestinian village of Beit Kahil in the southern West Bank so that engineers can plan the demolition.
“We have mapped the terrorists’ homes and we will soon demolish them,” Netanyahu said the following day, during a ceremony for the Shin Bet security service in Jerusalem.
Sorek’s body was found in the early hours of August 8 on a road leading to the religious seminary in Migdal Oz, where he was studying as part of hesder, a program that combines military service with Jewish study.
The terrorists fled the scene following the attack, leading security forces on a 48-hour manhunt before suspects were arrested in Beit Kahil at approximately 3 a.m. the following day.
Nazir’s brother Akrama and Qassem’s wife, Ines, were also arrested in the raid. A Shin Bet spokesman said security forces were looking into whether the two had helped the alleged killers hide after the attack.
A vehicle belonging to one of the suspects was also confiscated in the joint Shin Bet-Border Police-IDF raid. The army said that the car was “presumably” used in the attack.
Israel says the practice of demolishing terrorists’ homes is an effective means of discouraging future attacks, though it has been criticized by human rights groups as a form of collective punishment and by some analysts as an ineffective deterrent measure.
Jacob Magid contributed to this report.


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Predicted West Ham line-up to face Macclesfield Town in the EFL Cup
West Ham will host League Two side Macclesfield Town in the third round of the Carabao Cup on Wednesday.
The Hammers booked their place in the third round of the competition with a 3-1 victory at AFC Wimbledon. Macclesfield, meanwhile, have seen off Bradford City and Walsall to reach the last 32 stage of this competition.
West Ham held Chelsea to a frustrating 0-0 draw at the London Stadium in the Premier League this past weekend and manager Manuel Pellegrini will now be buoyant to face Macclesfield Town after that fantastic result.
Marko Arnautovic is not expected to play due to a knock, while Javier Hernandez is out with an illness.
Jack Wilshere is set to be sidelined due to an ankle injury, whereas the likes of Manuel Lanzini, Andy Carroll and Winston Reid are long-term casualties.
Probable West Ham XI
Manager: Manuel Pellegrini
Adrian should replace Fabianski in goal for this game against Macclesfield Town on Wednesday.
Ryan Fredericks (RB)
Fredericks has lost his place to Zabaleta but he could start this game.
Declan Rice (CB)
Although Declan Rice has excelled in the holding role for West Ham of late, he could find himself in central defence on Wednesday.
Angelo Ogbonna (CB)
Partnering Rice at the heart of the West Ham defence could be Ogbonna. He is a no-nonsense defender who will also be a threat to the opposition during set-pieces.
Aaron Cresswell (LB)
Cresswell is a highly energetic left-back who loves to get forward and contribute to his team’s attack. A fantastic crosser of the ball, Macclesfield have to be wary of his threat from dead-balls.
Carlos Sanchez (CM)
To protect the back-four and create a base for West Ham’s creative players to express themselves freely, Sanchez’s presence in midfield would be important.
Pedro Obiang (CM)
Obiang has been in really good form for the Hammers lately. He is a fantastic passer of the ball and possesses the vision to pick out his teammate. He is a definite starter on Wednesday.
Andriy Yarmolenko (RW)
Yarmolenko is finally starting to show his true colours. He could wreak havoc against Macclesfield with his pace and dribbling skills.
Michael Antonio (LW)
Antonio can play in a variety of positions but could start on the left wing on Wednesday. He is a tireless worker on and off the ball and Macclesfield will have to keep him at bay.
Robert Snodgrass (CAM)
Snodgrass could be deployed as the No.10. He is in good form and will look to impress the manager.
Read more: West Ham could do themselves a huge favour by rejecting offers for their 26-year-old powerhouse
Lucas Perez (ST)
First-team opportunities have been tough to come by for Lucas Perez; however, he could lead the Hammers’ attack on Wednesday.

domain: news


On a busy day for Parliament, Jason thanked our local teachers and support staff and asked the Education Secretary about military support for schools in rolling out mass testing.
Jason McCartney MP
I would like to thank all the wonderful teachers and support staff across my constituency and to welcome plans for all secondary and college students to receive two rapid tests at the start of term.
The Royal Air Force has already been helping to deliver rapid tests across Kirklees as part of mass community testing.
Has the Secretary of State considered using military support on the ground in schools and colleges, having done such a wonderful job in extreme circumstances in the past few months, to help deliver mass rapid tests and take the pressure off some of our teachers?
Gavin Williamson MP
I join my hon. Friend in his thanks. I know that he served in the Royal Air Force for a number of years, so he has a particular fondness for our armed forces, as we all do.
The armed forces have done an amazing job. Looking at the sheer number of schools across the country and the whole workforce within them, we felt that it would not be right or proper to ask the armed forces to deliver testing in every single secondary school.
That is why we have provided additional financial support for schools to help them deliver the mass testing regime.
We are very fortunate that my right hon. Friend the Secretary of State for Defence has agreed a Military Aid to the Civil Authorities request that means that we are able to provide military support to schools that are really struggling to set up a testing regime.
We believe that when they are set up, schools will be in an excellent position to keep running and have a real impact in driving down coronavirus infection rates in my hon. Friend’s constituency and all our constituencies.


text:
Febrile Neutropenia in Acute Leukemia. Epidemiology, Etiology, Pathophysiology and Treatment
Journal article, Peer reviewed
MetadataShow full item record
Original versionMediterranean Journal of Hematology and Infectious Diseases (MJHID). 2020, 12 (1), e2020009. https://doi.org/10.4084/mjhid.2020.009
Acute leukemias are a group of aggressive malignant diseases associated with a high degree of morbidity and mortality. An important cause of both the latter is infectious complications. Patients with acute leukemia are highly susceptible to infectious diseases due to factors related to the disease itself, factors attributed to treatment, and specific individual risk factors in each patient. Patients with chemotherapy-induced neutropenia are at particularly high risk, and microbiological agents include viral, bacterial and fungal agents. The etiology is often unknown in infectious complications, although adequate patient evaluation and sampling have diagnostic, prognostic and treatment-related consequences. Bacterial infections include a wide range of potential microbes, both Gram-negative and Gram-positive species, while fungal infections include both mold and yeast. A recurring problem is increasing resistance to antimicrobial agents, and in particular, this applies to extended-spectrum beta-lactamase resistance (ESBL), Pseudomonas aeruginosa, methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus (VRE) and even carbapenemase-producing Enterobacteriaceae (CPE). International guidelines for the treatment of sepsis in leukemia patients include the use of broad-spectrum Pseudomonas-acting antibiotics. However, one should implant the knowledge of local microbiological epidemiology and resistance conditions in treatment decisions. Here, we discuss infectious diseases in acute leukemia with a major focus on febrile neutropenia and sepsis, and we problematize the diagnostic, prognostic, and therapeutic aspects of infectious complications in this patient group. Meticulously and thorough clinical and radiological examination combined with adequate microbiology samples are cornerstones of the examination. Diagnostic and prognostic evaluation includes patient review according to the multinational association for supportive care in cancer (MASCC) and sequential organ failure assessment (SOFA) scoring system. Antimicrobial treatments for important etiological agents are presented. The main challenge for reducing the spread of resistant microbes is to avoid unnecessary antibiotic treatment, but without giving to narrow treatment to the febrile neutropenic patient that reduce the prognosis.

domain: literature


text:
The Houston Cougars stopped the SMU Mustangs on their first drive. The Cougars then took the ball and scored a touchdown to go up 7-0 with about half of the first quarter left to play.
Then came the thunder and lightning to join the rain and, just like that, there was no more football for two hours and twenty minutes. SMU returned to the field after the weather delay and tied the game at seven. Alas, for the Mustangs, this was the last time that they would be in the football game.
The Cougars, coming off last week's disappointing loss to the Rice Owls, scored the next 10 points to make it 17-7, and as the abbreviated half rolled around, the score was 24-10 Houston.
SMU scored first in the second half, making the score 24-17, but that's when Tyron Carrier went to work for the Cougars, taking the SMU kickoff 91 yards for the touchdown and putting the Cougars up 31-17 -- you probably didn't see this play as it was at about this time that CBS College Sports, in its infinite wisdom, cut away to another game, leaving Houston fans without a viewing option for the game.
The final score was 45-20 as the Cougars put together, without a doubt, their best game of the season, coming off, perhaps, their most disappointing loss of the season. That the Cougars won the game was important in that they had already lost two straight games and didn't want to have a losing record. But in defeating SMU, the Cougars not only have a winning record at 4-3, they're now 3-1 in C-USA play and tied with SMU for first place in C-USA's West Division.
"I couldn't be prouder of these guys, how they've handled adversity last week," Houston head coach Kevin Sumlin told radio sideline reporter Chuck Brown after the game. "A lot of people down on us, and how we came out and played on the road today. It's a great team win. We made plays on defense. Obviously made plays on offense. And the special teams came up big for us tonight, too."
And there was perhaps no play more important for the Cougars than Carrier's TD return for a touchdown. Not only did that answer a SMU score that had brought them to within seven points, but Carrier's TD gave the momentum back to the Cougars, and they did not relinquish that momentum the rest of the game.
The offense, which had trouble clicking in the first half against Rice, fired on all cylinders for the entire game as they employed a balanced attack that saw running backs Bryce Beall and Michael Hayes both rush for 87 yards and both score two touchdowns. Freshman QB David Piland continued to justify Sumlin's faith in him as he went 19 for 32 with a touchdown to Patrick Edwards and no interceptions.
"He's been coming along every week," Sumlin said of Piland. "We just haven't gotten any breaks, to be honest with you. We've got to help him, too. And I think we're doing that. We've got to turn into a complete football team instead of just waiting for our quarterback to win games for us. As I said two or three weeks ago, this thing is not very easy, but I think we're developing as a complete football team. And if we can do that, in the end we'll be better."
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SMU's offense was able to put 445 yards on offense, including 318 through the air, but the defense was able to stop SMU when needed. The Ponies were thus just never able to catch up to a Cougar team looking to quiet critics and to restore their own confidence.
"This is a great win for us, on the road, and it puts us back in the race," Sumlin said. "We truly can only handle one week at a time. What we have to do, with this football team, is remember how we prepared, what gave us the ability to win this game, and that starts on Monday. It doesn't start Friday, and it doesn't start in the second half of a game. It starts on Monday."
Today starts the preparation for the Cougars next game, where they will play the Memphis Tigers who are 1-6 (0-4 in conference) for the season. And if the Cougars play on Saturday anything like they did against SMU, then the Tigers are really not going to stand much of a chance.
SOME MISCELLANEOUS NOTES: Tyron Carrier's kickoff return for the TD was the sixth of his career. That leaves him one short of the NCAA record of seven set by C.J. Spillers when he was with Clemson. The kick return TD was his first since the Armed Forces Bowl on New Year's Eve....Carrier now has 5,033 career all-purpose yards. He's only the third Cougar to eclipse this mark....Bryce Beall's two-TDs give him 32 rushing TDs for his career, which is a UH record. It was also his fourth multi-TD game this season....This was Houston's fifth straight win against SMU, and they have won seven of the last eight. They are 15-9-1 all-time against SMU, including a record of 8-3 in Dallas.

domain: game


text:
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domain: agronomy


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text:
The George Brown College community is buzzing after three of our recent graduates won an international construction management competition.
Doan (Lucas) Dang, Nick Lourenco, and Mike Lino won the top prize at the Chartered Institute of Building's Global Student Challenge , beating out 53 teams from universities around the world. The GBC trio was the only college team and the only group from North America to make it to the final six.
Dang, Lourenco and Lino accepted their award at a ceremony in Toronto on July 12 as part of the CIOB 2018 Members Forum.
In the challenge, students use MERIT simulation software to run a virtual construction company and bid on projects against competitors. This simulation incorporates areas such as financing, human resources, bidding, project management and marketing. MERIT simulation is part of the curriculum in the Bachelor of Technology (Construction Management) program.
Dang, Lourenco and Lino were mentored by Andrew Gordon, a professor at the Angelo Del Zotto School of Construction Management, a construction management consultant and a CIOB Fellow.
Read more about the win in the Daily Commerical News .


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March 28, 2020. This was the last time I was at the gym just prior to its closure due to the covid pandemic lockdown in Edmonton. That is 15 weeks or 3.5 months ago. However, mentally and physically, it seems so much longer. As a physiotherapist, I am aware of the effects of deconditioning if I had stopped strength training completely. During this time, I was also training to run a half marathon and I could not afford to stop strength training. Fortunately, I have some access to weights, a TRX, plyometric boxes and resistance bands at my Clinic. At home, I loaded a backpack full of anything I could find that was heavy and did a lot of body weight exercises, single leg squats and heel raises. However, like many of us, I missed the heavy loads and the variety of exercises that only a gym could provide.
Deconditioning is the loss of training adaptations that occurs when one stops exercising. This applies to strength training and cardiovascular exercise. The extent of this loss is dependent on many factors and is not the same for everyone. People who have a longer exercise history, who have a higher initial strength and fitness level and who are younger will experience less of a decline.
So, what physiological changes can you expect if you had stopped strength training altogether this past 3 months?
In a study of older males aged 80+ years old, these participants started an 8 week resistance training program. This was followed by a cessation of the said program for 6 weeks. At the end of 8 weeks of training, muscle strength improved by 44%. At the end of the 6 weeks of stoppage, they only lost 25% of their gains (Kalapotharakos et al, 2010).
What is the take home message from this study? Be encouraged! The cessation of training for a short period of time does not result in a complete loss of your strength gains. Once we lose strength from detraining, how long does it take to gain it back?
A recent study by Blocquiaux et al (2020) took older males and started them on a 12 week whole body resistance program. Then they stopped for 12 weeks (just like us!) and then re-started them back again on the same training program for 12 weeks. So: training-detraining-training. What were the results?
Training: A 22% increase in knee extension strength at 8 weeks and 36% at 12 weeks.
Detraining: A 14% reduction in strength (again, not all is lost; participants were still 22% stronger compared to when they started the study)
Training: 24% increase from when they stopped. So, these participants were stronger at the end of the second 12 week period of training than they were after the first. It would have taken them only 8 weeks to regain what they had lost in 12 weeks.
Let’s take this further. What if someone detrains for a whole year? In a study by Correa et al in 2016, participants this time were female. In the first 12 weeks of resistance training, their gains were 75%. After a year of deconditioning, they lost nearly all of their gains, understandably so. But after 12 weeks of retraining, they gained 40% of their strength back, and on average, most were only 15% short of prior to stopping.
Take home message? Regardless of how long you have stopped exercising, the key is to return to it again and the time it takes to regain your original fitness levels is much shorter than the period of deconditioning. This is very encouraging.
In summary, what can we learn from all of these studies?
- When it comes to strength and cardiovascular endurance, you either “use it or lose it.” Deconditioning can occur very quickly especially during periods of bed rest or immobilization.
- Older people (80+ years old) can make incredible gains in muscle strength with resistance training. It is never too late to start and this is vital to combat the losses resulting from sarcopenia.
- All is not lost. Stopping exercise for an equivalent period compared to the period of training does not mean that you will lose all of your gains. In some situations, the loss can only be half. Of course, this will depend on many factors as mentioned earlier.
- You can regain your original strength levels in a shorter time period compared to the duration of cessation.
The caveat in all of these studies is that the participants were all healthy with no pre-existing injuries or medical conditions. If you are struggling with an injury or if you were strength training to rehab a pre-existing injury, then the time lines for these gains and losses can vary greatly and will most likely not follow a prescribed time line. It is best to take a more conservative approach in these cases: allow for a minimum of a 1:1 ratio for retraining. So, if you had an injury prior to the covid lockdown, then it’s best to allow 3.5 to 4 months at a minimum to return to pre-lockdown levels. Also, be sensitive to your emotional and mental health as well as burnout, prolonged negative stress levels, fatigue, anxiety, and depression for example will surely have an impact on your physical health as well.
A return to the gym is an exciting time for many of us. Understandably, some of us will still abstain from attending public gyms. Regardless, the key is to return to some form of strength and cardiovascular training as soon as possible. And if you start today (mid July), be assured that your body will thank you and will mostly likely reward you with gains back to pre-lockdown levels by mid September.
If you do choose to attend a gym, be careful. Enjoy and give yourself at least 3 months to regain your pre-lockdown strength but take more time if you need it.
Submitted by Albert Chan and adapted from an original article written by Claire Minshull, used with permission.
Kalapotharakos et al. Effects of resistance training and detraining on muscle strength and functional performance of older adults aged 80 to 88 years. (2010). Aging Clin Exp Res,22(2): 134-140.
Blocquiaux et al. The effect of resistance training, detraining and retraining on muscle strength and power myofiber size, satellite cells and myonuclei in older men. Exp Gerontol. May;133:110860. doi: 10.1016/j.exger.2020.110860. Epub 2020 Feb 1.PMID: 32017951
Correa et al. Effects of strength training, detraining and retraining in muscle strength, hypertrophy and functional tasks in older female adults (2016). Clin Physiol Funct Imaging. 36: 306–310

domain: health


I just saw a report on Daily Kos (see link to the right) that says that an open gay Arabic translator (and West Point grad) who challenged DADT in court has been recalled to active service. The presumption is that this is an indication of the new Department of Defense policy on enforcing DADT (they aren't anymore).
Tuesday, February 09, 2010
I think this is great. When the the sky fails to fall over this, another chunk of public opinion will come around to the idea of full and equal rights for all citizens regardless of sexual preference.
I know we've got some contributors and friends of the blog who know a thing or two about this issue and about the Defense department in particular. I'd like to hear their take on this and other developments.
Posted by Raised By Republicans at 4:31 PM


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text:
Tyrone maintained their perfect start to the season with a deserved win over a robust Galway side at Tuam last Sunday making it five victories from five starts in this year’s league campaign. That win not only extended the team’s 100% record but also ensured promotion to Division One for next season so objective number one has been well and truly achieved.
For the large crowd of Tyrone supporters who made the journey west there was the satisfaction of the win but more importantly the continued development of this young team. Tuam has never been an easy venue for Tyrone teams in the past and Galway were keen to let the Red Hands know they were going to have to battle for the points. When the top two sides in the league meet, games like these are worth much more than just the two points for the winner. There is the huge psychological boost that comes with heading away from home and earning the win. And earn it they did as Galway made Tyrone battle all the way for the win.
In a match where there were many issues for discussion the topic on most folks’ minds was the superb display from young forward Kyle Coney who landed four excellent second half points from play. No one has ever doubted the talent of the young Ardboe ace but some would have questioned his willingness to work for the team. Well on Sunday he showed a side to his game which would appear to suggest he has bought in to the work ethic on which this team is built. Along with his full forward colleague Owen Mulligan Coney worked his socks off for the team defending when required and attacking with purpose when asked. It was a very good team performance but the corner forward deserves special mention for his outstanding point taking which helped seal victory for Tyrone.

domain: sports


The seventh year of back-to-school tax-free shopping is nearly upon us in Georgia.
From 12:01 Thursday morning to midnight Sunday, selected school supplies will be exempt from state sales tax.
Whether this is your first year dressing your child in school uniforms or it's become old hat to you, Pat Grace of Patrick's Uniforms is hoping you'll stop by her store.
Grace, president of the store, which recently moved from southside Savannah to 2307 U.S. 80 West in Garden City, said her store has everything you're looking for, and great customer service to boot.
"We specialize in hard-to-fit kids and real large kids," she said. "Most stores carry the easy part, but we go up to size 60 in pants and up to size 6X on the shirts. We're able to offer a lot for the bigger kids."
Keeping to local stores is possible in Bryan County as well.
Alco, described as a mini Target, opened last November in Pembroke. This is its first year participating in the tax-free holiday, but store manager Mikela Critzer says they've got what you need.
The store carries shoes, clothing and school supplies. While they don't carry computers, she said the store does offer computer printers and printing supplies.
She said the store is the only department store in north Bryan County, and she hopes that will be a big draw for locals. "I would like to see all of Pembroke and the surrounding communities shop here," Critzer said.
She pointed out that filling back-to-school needs locally means residents will save on gas, and she promised that her store would provide friendlier customer service than some of the bigger chain stores in surrounding areas.
David Smith, owner of Computer Solutions & Office Supplies in Richmond Hill, also hopes citizens will shop locally.
This is the store's third tax-free holiday, but the first in which Smith is trying to drive customers to stay local. He said the store is offering 20 percent off all office and school supplies for the entire month of August.
On July 29, he hung a large banner outside the store, announcing the sale and adorned with his "save gas, shop local" motto for the tax-free holiday.
"We're trying to get people to stay here," he said. "What people don't realize is we're just as competitive, if not cheaper, than going all the way to town."


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Family in Hospital after Gas Leak
7:00am 23rd January 2013
Two children and their parents have been rushed to hospital after carbon monoxide flooded through their home near Launceston.
Paramedics were called to Canworthy Water in the early hours of Wednesday morning after the family said they were not feeling well.
A spokesperson for Cornwall Fire and Rescue Service said: "An appliance from Launceston and a Wholetime Officer attended a property in Canworthy Water on the request of the Ambulance Service due to occupants feeling unwell due to possible carbon monoxide poisoning.
"On arrival crews used a gas detector which indicated high readings of carbon monoxide within the property.
"Two adults and two children were taken to hospital by ambulance, whilst crews made the property safe by venting using a positive pressure ventilation fan.
"Crews also fitted two smoke detectors within the property."
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UK warned Brexit bill will be 'very hefty' and EU trade deal will take years
National News: Britain will be landed with a "very hefty bill" to get out of the EU exit door, European Commission President Jean-Claude Juncker has warned.
David Cassidy reveals he has dementia after forgetting songs
Showbiz News: Former teen idol David Cassidy has revealed he has dementia, after forgetting the words to his own songs during concerts last weekend.
Man dies in shark attack off Reunion Island after ignoring danger warnings
World News: A man who ignored warnings not to surf off the coast of Reunion Island has died after being bitten on the leg by a shark.
FA and Gambling Commission probe Sutton goalkeeper Wayne Shaw's pie-eating
Sports News: Sutton goalkeeper Wayne Shaw is at the centre of a betting probe after eating a pie on the substitutes' bench during an FA Cup defeat to Arsenal.
Newspaper apologises after using Baldwin SNL photo instead of Trump
Strange News: A newspaper in the Dominican Republic has had to apologise to readers after it mistakenly used a photo of Alec Baldwin impersonating Donald Trump instead of the US President himself.


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Good morning Nigeria, welcome to Naija News roundup of top newspapers headlines in Nigeria for today, Wednesday, 5th January 2022
The Minister of Justice and Attorney-General of the Federation, Abubakar Malami, has revealed why the President Muhammadu Buhari-led government has not officially declared bandits as terrorists.
Malami on Tuesday stated that his office is in the process of announcing the court judgement that directed the Federal Government to declare bandits as terrorists.
The AGF, while speaking on NTA Good Morning Nigeria Show, said the process would be concluded in a matter of days.
Recall that Justice Taiwo Taiwo of the Federal High Court on November 26, 2021, granted an ex parte application by the Federal Government for Yan Bindiga (Hausa word for gunmen) and Yan Ta’adda (Hausa word for terrorists) to be declared as terrorists.
Malami in his statement on Tuesday said the government acted swiftly in declaring IPOB and Boko Haram as terror groups because of the “threats to lives and properties they have caused in the nation.”
2. Imo: Okorocha Is My Younger Brother, Says Uzodinma As He Fails To Name Terrorism Sponsors In The State
Imo State Governor, Hope Uzodinma on Tuesday failed to release the names of specific persons sponsoring insecurity and terrorism in the state.
Naija News recalls ahead of the Imo state stakeholders meeting/luncheon which took place on Tuesday, the Governor had raised expectations when he revealed that he would use the opportunity to disclose names of individuals behind the insecurity ravaging the state and also highlight his achievements in office within the last two years.
He made this known in a statement on Sunday by the state Commissioner for Information and Strategy, Hon Declan Emelumba.
However, the Governor during the stakeholders’ meeting held at the Sam Mbakwe Executive chamber in the government house in Owerri made a u-turn on his earlier promise when he failed to disclose any specific person as responsible for the insecurity in Imo.
Uzodinma stated that he observed that his promise had caused tension in the state and would therefore allow the security agents to conclude their investigation and reveal those responsible for the attacks in Imo.
Governor Babajide Sanwo-Olu of Lagos was on Tuesday embarrassed by an unnamed Chief Superintendent of Police.
Naija News reports that the CSP openly defied the order of the Lagos State Governor to vacate the Magodo Phase 2 Estate area of the state.
Recall that security operatives had besieged the estate in the company of suspected land grabbers and members of a family who had planned to execute a Supreme Court judgment.
This development had cause commotion as residents called on Sanwo-Olu to intervene.
The Lagos governor had on Tuesday visited the estate and told the leader of the security operatives to vacate the premises as the matter was between private individuals and the state government.
But to the suprise of those around, the CSP told the governor that he and his colleagues were at the estate on the orders of the Inspector-General of Police, Usman Baba; as well as the Attorney General of the Federation, Abubakar Malami (SAN).
The Minister of Justice and Attorney-General of the Federation, Abubakar Malami, on Tuesday revealed what will make President Muhammadu Buhari release the leader of the Indigenous People of Biafra, Nnamdi Kanu.
Malami said President Buhari will consider the interest of over 200 million Nigerians before he can grant the request to release Kanu.
The minister stated this while speaking on NTA’s Good Morning Nigeria Show.
This is coming after a former Minister of Aviation, Mbazulike Amaechi led some Igbo leaders to visit the President for the unconditional release of the IPOB leader.
Buhari during the visit told them he would not want to interfere in the running of the judiciary but said he would consider their demand.
Malami when asked on Tuesday about the request of the Igbo leaders said Buhari would consider the interest of Nigerians before he takes any decision.
The Nigerian Air Force (NAF) has approved the appointment and redeployment of some top commanders, new Branch Chiefs, Air Officers Commanding (AOCs), Commandants of tri-Service and NAF institutions as well as Unit Commanders.
A statement on Tuesday by the NAF Director of Public Relations and Information, Air Commodore Edward Gabkwet stated that the shake-up was approved by the Chief of Air Staff, Air Marshal Oladayo Amao.
While noting that postings and redeployments in the military are routine exercises intended to reinvigorate the Services for greater performance, enhanced productivity, operational efficiency, and effective service delivery, the statement urged the officers to justify the confidence reposed in them leading to the appointment.
Naija News reports that all the newly appointed and redeployed senior officers are expected to assume their new offices on or before Friday, 7 January 2022.
President Muhammadu Buhari on Tuesday approved the appointment of Dr. Doyin Salami as his Chief Economic Adviser.
Naija News reports that Dr Salami was the Chairman of the Presidential Economic Advisory Council, PEAC.
Salami is a 1989 doctorate degree graduate of Economics from the Queen Mary College, University of London.
The 59-year-old is the Managing Director and Head Markets Practice at KAINOS Edge Consulting Limited, and member of the Adjunct Faculty at the Lagos Business School (LBS), Pan-Atlantic University, where he recently attained the rank of Senior Fellow/Associate Professor.
Naija News reports that the Chief Economic Adviser to Buhari is expected to address all issues on the domestic economy and present views on them to the President.
The Adviser is also expected to closely monitor national and international developments, trends and develop appropriate policy responses; develop and recommend to the President national economic policies to foster macro-economic stability, promote growth, create jobs, and eradicate poverty, among others.
Some inmates in Kosere Correctional Centre, Ile Ife, Osun State, attempted to escape on Tuesday but were repelled by security operatives.
Naija News gathered that one of the inmates attacked a prison warden, while others forced their way through the entrance of the prison facility.
Speaking with The PUNCH, a security source revealed that four inmates were shot dead while attempting the jailbreak during the morning sanitation.
As of the time of filing this report, that Osun State Comptroller of Corrections, Lanre Amoran, had visited the facility for an on-the-spot assessment.
The Nigerian Senate has said it was very lucky to have held plenary sessions for only 66 days in 2021 due to the COVID-19 pandemic.
Naija News reports that the spokesman of the Red Chamber, Senator Ajibola Basiru, made the submission during an appearance on Channels Television on Tuesday.
Bashiru stated that the COVID-19 pandemic forced the Senate leadership to reduce the number of days of plenary from three to two days due to the increased cases of the dreaded virus in the country.
He agreed that the Senate failed to meet the 181 days stipulated in Section 63 of the 1999 constitution, but didn’t violate the law.
The Senator argued that the lawmakers have not contravened the provision of the constitution in any way because it was a matter of emergency.
The Peoples Democratic Party (PDP) has reacted to the rumours that former President Goodluck Jonathan is planning to defect to the All Progressives Congress (APC).
Reports emerged on Monday that Jonathan has intensified his move to return to Aso Rock in 2023 after meeting with his supposed campaign coordinators.
It was learned that the former president met with coordinators on December 27, 2021, at Aridolf Hotels and Spars in Yenagoa, Bayelsa State.
Reacting to the reports, PDP spokesman, Debo Ologunagba, said the opposition party is confident that the Nigerian leader will not join the ruling party.
Ologunagba stressed that the PDP leadership is reaching out to every member of the party to join the rescue mission of the country ahead of the 2023 Presidential election.
He disclosed that the PDP is not aware of Jonathan entering into any form of talks with the APC in a bid to join them and run for presidency.
Eight commissioners have been sacked and eight others retained as Governor Samuel Ortom of Benue State dissolved his cabinet.
This was made known in a statement issued on Tuesday by Secretary to the State Government, Prof. Anthony Ijohor.
According to the statement, the governor advised the sacked commissioners to hand over to Permanent Secretaries in their respective ministries.
He, however, expressed his profound appreciation to the outgoing commissioners for their service to the State and wish them well in their future endeavours.
Those are the top Nigerian newspapers headlines for today. Read more Nigerian news on Naija News. See you again tomorrow.
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Either the option of just the tabletop unit itself same time we will put together a personalised quote you will place it in the office. Do you want to register.
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How it works: Most steam ovens and combination ovens nut is easily fits onto the dishwasher upper spray The basket handles make loading and unloading easier.
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Coil Binding System
Punch [TB58644E] / Opener [TG72561E] / Inserter [TB58805E] / Closer [UL02821E]
115V / 60Hz
This GBC Coil Binding System includes 4 GBC modular binding machines along with 4 Dies, new surplus combs, coils & twin loop wire. Please see specsheets which include videos and specifications for each unit. All machines and supplies came from the same shop. These are used machines which have been well maintained and are in good working condition. These items are located in Topeka, KS and will ship via Freight truck from that location. Please contact us if you have any questions.
Spec Sheet available! CLICK HERE
Video Available! CLICK HERE
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Gitmo: Kansas says no
Leavenworth should be crossed off the list of potential communities to house detainees
There's a school of thought that says moving the Guantanamo Bay detainment facility to Fort Leavenworth would be good for Kansas because it would bring an influx of jobs and federal dollars to the state.There's also a school of thought that says moving the detainees would pose no more of a risk to Kansans than relocating the National Bio- and Agro-Defense Laboratory from Plum Island, N.Y., to Kansas State University, a project state leaders embraced.But weeks after the move was first proposed, it's become clear that the arguments in favor of transferring the detainees haven't taken root among the people closest to the situation.Leavenworth city officials and state leaders remain convinced the proposal is a bad idea, which is enough to convince us it's time to take it off the table."Kansans: Not in our backyard," read a headline Monday in USA Today.The story quoted Leavenworth's mayor and police chief, as well as other city leaders and residents, saying the city isn't the right place for the detainees."Is it really a bad thing not to want it in your backyard if you've got a really good, solid explanation?" Mayor Lisa Weakley asked. "We have geographical challenges, security concerns and economic concerns. These are different types of prisoners than we're used to."Among the concerns of community leaders:• The detainee facility would be difficult to secure. The site of the U.S. Disciplinary Barracks, where the detainees would be incarcerated, is near the Missouri river and railroad tracks that carry 50 trains per day.• The presence of the detainees might prompt some contries to refuse to send officers to the Command and General Staff College at Fort Leavenworth.• Leavenworth could become a target for extremists.A bipartisan group of Kansas governmental leaders shares the concerns of city leaders. Gov. Kathleen Sebelius lined up against the idea before President Obama nominated her as secretary of Health and Human Services, as did Republican Sens. Pat Roberts and Sam Brownback and other state and federal lawmakers.So this is more than a knee-jerk, NIMBY (Not In My Backyard) issue.The chilly reception the plan received in Kansas hasn't thawed over time.Fact is, it appears nobody wants the detainees. Efforts to bar them have taken root in Indiana, California, South Carolina, Texas, Colorado and Arizona.Now that Obama has signed an order to shut down Guantanamo Bay within a year, what happens from here is anybody's guess. Some detainees may have to be sent to a U.S. detention facility.We'll add our voices to those who believe they shouldn't be sent to Kansas.


Kibblewhite Precision Machining Nitrided Exhaust Valve - 20-20265
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Alternate/OEM Part Number(s):


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Ryan Tubridy has responded to Shane Lynch's claims of 'bullying behaviour' during a 2018 interview on the Late Late Show.
The former Boyzone star said he hadn't spoken to the RTE presenter since their interview, during which he exploded on-air.
Today's top videos
STORY CONTINUES BELOW
Lynch became angered when the infamous clip of Boyzone dancing on a 1993 edition of the Late Late Show was played during his appearance.
Asked recently about the incident by the Irish Sun, Shane said: 'I haven't spoken to Ryan since. RTE promised they wouldn’t show that clip. That it would be a positive interview but they threw us under a bus.
'Showing that clip was a massive bullying tactic in my eyes.'
Asked if he knew Lynch felt so strongly about the video, Tubridy said: 'No, I had no idea and that is desperate because he is a lovely fella, he is good craic.
'I don’t know him at all other than I’ve met him once or twice on TV.
Speaking to RSVP Live, Tubridy said: 'And that was an unfortunate outcome for Shane because of course that clip is one that would be played every time he goes to venture towards a studio.
'So hopefully he gets that sorted out.'
Asked if he would show the clip again, Tubridy said: 'I think if it is something that Shane is triggered by it, it is something we’d surely have to discuss in advance because I wouldn’t want him being upset at seeing himself as a young man auditioning on the Late Late Show.'
Lynch has maintained that the show's producers said they wouldn't show the clip, but Tubridy said he was not involved in any such conversation.
Tubridy said: 'That would be an unusual thing to happen and I wouldn’t be privy to that conversion. I’m not sure it would be the answer to that, so can't help you there.'
Tubridy also confirmed there will be no Late Late Show audience for the rest of the year, saying he wasn't keen on the idea of a partial audience.


This is the Geo-ring. I designed this using TinkerCAD.
Step 1: First Step to Design the Geo-ring
Measure the diameter of the finger you will use to wear the ring.
Step 2: Step 2
Make a cylinder hole that matches your finger size.
Step 3: Step 3
In this step, you will need a twisted polygon. Add the twisted polygon and adjust the top twist to -153 and the bottom twist to 180. After doing this you need to adjust the length and width of your twisted polygon to about 5mm bigger than your cylinder.
Step 4: Step 4
In this step, you will need to use the align feature to place the cylinder hole in the center of your twisted polygon.
Step 5: Step 5
In this step, you will group the two shapes together to make them become a Geo-ring.
Step 6: Last Step
3D Print your Geo-ring. You may use the .stl file of it that I have provided.
Participated in the


Holton took early control leading 16-0 and 22-8 by halftime, but Sabetha took over in the second half outscoring the Wildcats 17-0, holding them to 47-yards of offense in the second half and recovering a late fumble to set up a game winning 28-yard field goal by Braden Cox with nine seconds left in the game. Blake Plattner led the Bluejays on the ground with 138 yards on 15 carries with a TD, while Trae Synder ran for 128 yards on 23 carries with a TD. Christian Meyer added a TD run.
Holton had Spencer Baum run for 151 yards on 18 carries in the loss, while Miles McClintock-Strozier had 11 carries for 75 yards and a TD and Parker Zeller added a TD run.
The win over Holton is the first for Sabetha since 2007.


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domain: artistic


From the US of A to Sydney
“My experience at St. Andrews has been better than anything I could have imagined before I started. Even as the “new kid”, I felt instantly welcomed and could feel the inclusive, friendly nature radiating off of the staff and students… I couldn’t be prouder to be able to say I attended St Andrews,” – Austin Vargo, Exchange student from Texas, USA.
Exchange programmes might be increasingly common in universities, but in secondary schools they remain a rarity. There are numerous long-term benefits of exchange for both the travelling student and the exchange family: a deeper understanding of alternate cultures and lifestyles, fresh perspectives, and for the exchange student particularly, a one-time chance to critically review their education against that of other institutions.
For five months this year, Texas student Austin Vargo lived with a family from St Andrew’s. She assumed their lifestyle, accustomed herself to their habits and attended the Senior College as an International Baccalaureate (IB) student. “One of the best things about the school was the mixture of students,” Austin wrote, in a thank you letter to St Andrew’s Registrar. “I made friends with kids from Surry Hills, Bronte, Willoughby, Sutherland, and many other places. That was something special for me because schools back home consist of students within a certain [residential] zone. This sampling of different locations helped me see different parts of Sydney outside of just Chatswood.”
It was after much consideration that the Simpson family decided that hosting a foreign student would be “a good way to extend our little family”, comprised of mother, father and son Jordan Simpson (Year 10). After researching several organisations, they decided on Student Exchange Australia as “they presented us with several student profiles from the countries of our choice.” Mr Andrew and Margaret Simpson explain that although there were ups and downs – as could be expected from temporarily opening up your family –the overall experience was reaffirming and one they’d recommend to others. “At a very basic level it made us all appreciate each other and the time we have together more. It taught us all how to care for and accept another person … [On top of that], Austin was extremely disciplined in doing her schoolwork and getting places on time, and Jordan absorbed a lot about that from her.”
Though she hadn’t cooked before she visited Australia, by the time Austin left she could prepare a whole meal and had made pasta by hand. She had also snorkelled at Shelley Beach, where she saw a five foot Wobbegong shark. One of the biggest changes she experienced however was bigger than the kitchen, even bigger than a trip to Sydney’s South. The shift in education was significant. Her school at home did not have uniforms, and while it took some adjusting, Austin admits she found it “refreshing” as “the competition between students to dress better than everyone else was totally eliminated.” For the first time, she was involved in school sport, physical activities run by specially trained staff.
The school size was another differentiator. As Austin explains, “My grade back home consisted of about 650 students, with class sizes of more than 30. The IB programme was extremely beneficial in this way. My largest class probably had about 17 students in it and the effect is obvious. More student-teacher interaction as well as a more orderly classroom made learning much easier here than in Texas.” Smaller class sizes also enabled Austin to experience greater care within the classroom, where teachers genuinely showed interest in her emotional wellbeing. As the course material was more difficult than Austin was used to, the heightened teacher/student interaction became crucial, alongside a newly developed homework regime (changes Margaret says that Austin “took in her stride”).
So what were Austin’s favourite new classroom experiences? “Theory of Knowledge and Creativity Action Service (CAS) were some of the most useful classes I have ever taken,” she shares. “[The subject] promotes questioning the world and employing philosophical skills to better perceive the world around us. CAS is a genius idea by the IB used to make sure the IB student is not only academically accomplished, but also a well-rounded person who can show creativity, athleticism, and compassion through helping others… Although the IB program is challenging, I feel as though you grow as a person instead of just expanding your knowledge.”
Though Jordan was one school year younger than Austin, he was still excited to share his learning space of over seven years with a new face. “For about the first two weeks Austin and I stuck together, just until she got used to the St Andrew’s lifestyle,” Jordan explains. “By the third or fourth week she had her own friend groups and was managing the school and the commute really well… It was a great honour to show off all of what St Andrew’s had to offer, especially since the school she is currently in – to my understanding – is not [as] accepting... I don’t think she could really comprehend that it didn’t matter where you came from, who your parents were, or what your background was, St Andrew’s students were always going to be friends to her and be there for her.”
Austin is now back with her family in Texas. When she has finished Year 12, she hopes to study Marketing at New York University. We wish her all the best and thank her for joining our school, even if just for a little while.
Words: Laura Bannister


text:
Nervous Breakdown - Mental Breakdown - Treatment - Therapy - Symptoms
A Nervous breakdown is a general term for various mental health symptoms, which may include, anxiety, depression, low self esteem, loss of interest, loss of energy, for more info about a nervous breakdown / mental breakdown goto therapy247.com
By: Billy fitz
from Daniel K. Hall-Flavin, M.D.
The term "nervous breakdown" is sometimes used to describe a state in which a person is so severely and persistently distraught that he or she is unable to function at a normal level. Nervous breakdown isn't a medical term, however, nor does it indicate a specific mental illness.
Often, a nervous breakdown indicates depression. Signs and symptoms of depression may include:
■Loss of interest in normal daily activities
■Agitation or restlessness
■Trouble concentrating and making decisions
If you're concerned that you're experiencing a nervous breakdown, seek medical attention. If you have a primary care doctor, talk to him or her about your signs and symptoms — or seek help from a mental health provider.
For help and therapy goto http://www.therapy247.com .
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domain: medical


text:
Japan only now confronting rising HIV rate / Women in sex trade most at risk - SFGate Prostitutes Muramatsu
- Buy Hookers Muramatsu
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They also complain that Prostitutes education in primary and middle schools, which began only last year, focuses on eliminating Prostitutes against those with HIV instead of teaching about safe sex. In fact, many Japanese believe it is a problem only for Muramatsu Third Muramatsu countries.
Numerous surveys have shown that most men and women in their 20s don't use condoms, often justifying their behavior by saying they are in a monogamous relationship. The Health and Welfare Ministry blames declining condom use for the spread of the disease. Police seek woman who took violin off Muni bus. Photo by Suvendrini Kakuchi, special to the Chronicle less.
Buy Hookers Muramatsu
AIDS activists say attempts to educate teens have been stymied by teachers and parents, who argue that such programs encourage sexual activity.
Prostitutes of God (Documentary)
Phone numbers of Prostitutes Muramatsu Japan Niigata 1856426
Photo by Suvendrini Kakuchi, special to the Chronicle less.
Homeless man in his 40s struck, killed by box truck on The women -- employed by massage parlors called fasshon herusu, or " fashion health" -- are discussing ways Prostitutes avoid AIDS and other sexually transmitted diseases and still keep Prostitutes jobs if a client insists on not using a condom.
California bill would crack down on package theft.
- But most recently, there has been a dramatic increase in AIDS cases caused by Prostitutes sex.
- AIDS activists Muramatsu attempts to educate teens have been Muramatsu by teachers and parents, who argue that such programs encourage sexual activity.
- Back to Gallery.
- Will a new owner continue the legend?
- Soapland operators, for example, skirt the law by billing themselves as "assisted bathhouses.
- East Bay 2-year-old and her mother missing and in danger.


text:
ROCHESTER, N.Y. (WROC) — Tuesday marks day one of Rochester’s 2022 Fringe Festival and businesses in the area of East Avenue and Gibbs Street say they’re eagerly anticipating a boost in customers.
This year’s iteration will be the first full-blown Fringe Fest since before the pandemic. In 2020 organizers kept it online-only, and in 2021, the event was hybrid. Owner of Ludwig’s Center Stage Café Emma Goole says for a typical year, hundreds of people can be spotted in the streets.
She says the family-owned café has been on Gibbs Street since 2012. The past few years have been challenging, with the pandemic, staffing shortages, and other festivals taking hiatus.
“We were closed for most of it, then we would reopen, and close again,” she said. “We lost most of our employees during that.”
But this year feels reminiscent to pre-pandemic times.
“So we’re excited for Fringe,” she said. “That’s a thing we’re used to, really nice to have back.”
Organizers say after last year’s hybrid run, many performing artists have been eager to get back at it — acts ranging from music, comedy, theater and dance.
Michael O’Leary, owner of Temple Bar and Grille says the strip of businesses on East Avenue, needs all the help it can get with the effects of construction, inflation, and the pandemic still looming.
“All the businesses here used to be open for lunch,” said O’Leary. “Now very few of us are.”
He’s hopeful for these next few weeks, though. Especially with some new businesses setting up shop in the neighborhood, soon.
“We’re hoping for some big things, and hoping people come down and enjoy the festival.”
O’Leary says unlike Ludgwig’s, they did not experience a surge in traffic for the Jazz Fest. The reason, due to organizers moved it down a few blocks towards Parcel 5. He’s hoping next year, they might be able to move vendors and musical acts more towards the bar district.

domain: economics


text:
Brand and Other Names:Saphris
- Classes: Antipsychotics, 2nd Generation
Dosing & Uses
Dosage Forms & Strengths
5 mg SL q12hr initially; maintenance: after 1 week, may be increased up to 10 mg PO q12hr
Manic or mixed episodes associated with bipolar I disorder, either as monotherapy or as adjunct to lithium or valproate
Monotherapy: 10 mg PO q12hr initially; may be decreased to 5 mg PO q12hr on day 2 and subsequent days if warranted by adverse effects or individual tolerance (90% of patients typically remain on higher dose)
Adjunct to lithium or valproate: 5 mg PO q12hr initially; may be increased to 10 mg PO q12hr if warranted
If patient responds favorably, continue beyond initial acute phase (no recommendations at this time for duration of therapy)
- Dose adjustment not necessary
- Mild to moderate impairment (Child-Pugh class A or B): Dose adjustment not necessary
- Severe impairment (Child-Pugh class C): Contraindicated
Dosage Forms & Strengths
Indicated as monotherapy for acute treatment of manic or mixed episodes associated with bipolar I disorder
<10 years: Safety and efficacy not established
10-17 years: 2.5 SL q12hr initially; may increase to 5 mg SL q12hr after 3 days and to 10 mg SL q12hr after 3 additional days
Pediatric patients are more sensitive to dystonia with initial dosing when recommended escalation schedule not followed
Safety and efficacy of doses >10 mg q12hr not established
Not indicated for dementia-related psychosis, in view of increased risk of death as compared with placebo (see Black Box Warnings)
In elderly patients with psychosis, asenapine exposure (area under curve [AUC]) was on average 40% higher than in younger adults
Serious - Use Alternative
Significant - Monitor Closely
- Oral paraesthesia (27%)
- Somnolence (49%)
Extrapyramidal symptoms (EPS) other than akathisia (7%)
Weight gain (5%)
Oral hypoesthesia (4%)
Dry mouth (3%)
Extremity pain (2%)
- Nausea (6%)
- Abdominal pain (6%)
- Fatigue (9%)
- Increased weight (3%)
- Hyperinsulinemia (2%)
- Increased appetite (8%)
- Headache (9%)
- Dizziness (7%)
- Dysgeusia (6%)
- Akathisia (2%)
- Insomnia (3%)
- Suicidal ideation (3%)
- Tachycardia (1%), Glossodynia (1%), Irritability (1%), Muscle pain (1%), Increased ALT (1%), Increased AST (1%), Dehydration (1%), Myalgia (1%), Parkinsonism (1%), Anger (1%), Dysmenorrhea (1%), Rash (1%), Nasal congestion (1%), Dyspnea (1%), Oropharyngeal pain (1%)
Sublingual administration: Application site reactions including oral ulcers, blisters, peeling/sloughing, and inflammation
Choking reported by patients, some of whom may have also experienced oropharyngeal muscular dysfunction or hypoesthesia
Black Box Warnings
Not indicated for dementia-related psychosis; increased risk of death in elderly patients with dementia-related psychosis; placebo-controlled trials with other atypical antipsychotics (ie, risperidone, aripiprazole, olanzapine) showed higher incidence of cerebrovascular adverse reactions (eg, cerebrovascular accidents [CVAs], transient ischemic attacks [TIAs]), including fatalities, in comparison with placebo
Severe hepatic impairment (Child-Pugh C)
Type 1 hypersensitivity reactions, including anaphylaxis and angioedema, have been reported (n=52), in several cases occurring after first dose; symptoms include anaphylaxis, angioedema, hypotension, tachycardia, tongue and laryngeal edema, difficulty breathing, wheezing, or rash
Neuroleptic malignant syndrome associated with use; monitor for symptoms and discontinue if necessary
Extrapyramidal symptoms, including acute dystonic reactions, pseudoparkinsonism, akathisia, and tardive dyskinesia reported
Hyperglycemia (monitor patients with diabetes mellitus for worsening of glucose control)
Weight gain may occur; monitor weight gain in pediatric patients and assess against that expected for normal growth
Hypotension and syncope, especially early in treatment, because of drug's alpha1-antagonistic activity
Leukopenia, neutropenia, and agranulocytosis reported with use
Possible prolongation of QTc interval; avoid in patients with history of cardiac arrhythmias or other conditions that increase risk of torsades de pointes (eg, bradycardia, hypokalemia, hypomagnesemia)
Coadministration with other drugs that prolong QTc interval may result in life-threatening arrhythmias (eg, class 1A antiarrhythmics [quinidine, procainamide], class 3 antiarrhythmics [amiodarone, sotalol], antipsychotics [ziprasidone, chlorpromazine, thioridazine], and antibiotics [moxifloxacin])
Concurrent use of CNS-acting drugs or alcohol may increase toxicity
Use caution in patients with history of seizures
Cognitive or motor impairment may occur due to CNS depression
Dysphagia, dysmotility, and aspiration may occur
Potential disruption of body temperature regulation
Not recommended with severe hepatic impairment (Child-Pugh class C)
Inherent suicide risk with population treated warrants close supervision when drug therapy is changed
May increase prolactin levels; significance unknown
Atypical antipsychotic drugs have been associated with metabolic changes including hyperglycemia, dyslipidemia, and body weight gain, which may increase cardiovascular/ cerebrovascular risk; all of the drugs in the class have been shown to produce some metabolic changes but each drug has its own specific risk profile
Monitor weight gain in pediatric patients and assess against that expected for normal growth
Pregnancy & Lactation
Pregnancy category: C
Neonates exposed to antipsychotic drugs during 3rd trimester of pregnancy are at risk for EPS or withdrawal symptoms after delivery; these complications vary in severity, with some being self-limited and others requiring ICU unit support and prolonged hospitalization
Lactation: Excretion in milk unknown; use with caution
A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA:Information not available.
Mechanism of Action
Mechanism of action unknown; efficacy thought to be mediated via combined antagonist activity at dopamine D2 and serotonin type 2 (5-HT2) receptors
Bioavailability: SL, 35%; swallowed, ≤2%
Peak plasma time: 0.5-1.5 hr
Peak plasma concentration: 4 ng/mL
Protein bound: 95%
Vd: 20-25 L/kg
Metabolized by UGT1A4 and CYP450 (predominantly isoenzyme 1A2)
Enzymes inhibited: CYP2D6 (weakly)
Half-life: 24 hr
Clearance: 52 L/hr
Excretion: Urine (50%), feces (40%)
Sublingual tablet; to allow optimal absorption, place under tongue and allow to dissolve completely (dissolves within seconds)
Do not chew, split, crush, or swallow sublingual tablet
Do not eat or drink for at least 10 minutes after administration
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Kentwood Floors to be featured at fall LG Fashion Week
VANCOUVER, British Columbia (12 July 2010) - Hardwood flooring manufacturer Kentwood Floors has been named a contributing sponsor to the upcoming edition of LG Fashion Week, this country's premiere fashion industry trade event.
Kentwood will design and create the runways for the live fashion presentations that will be held throughout the week-long event, which will be held in Toronto from 18 through 23 October 2010.
"We think our products are all about making a fashion statement with your home, and style is a big part of our brand's appeal," Kentwood vice president of sales and marketing Brady Page, said in a statement, adding, "This is an opportunity to showcase Kentwood's design philosophy in an environment that is internationally recognized for setting the standard of fashion and style."
Formally known as LG Fashion Week Beauty by L'Oreal Paris, the bi-annual event is a week-long extravaganza showcasing the finest in Canadian fashion a full week of themed events; industry parties; product presentations; and, live fashion shows by some of Canada's foremost designers.
Held each spring and fall and now in its 11th year, the Toronto edition has become the second largest fashion week event in North America. It's organized by Fashion Design Council of Canada (FDCC) and spearheaded by executive director Robin Kay.
"This is a great opportunity not just to promote our brand and our product line, but also to challenge our designers to create a style of flooring that is very special and innovative, something that expresses the spirit and philosophy of this exciting event," Page said.
Kentwood maintains a web site at www.kentwoodfloors.com/ca.
More information about LG Fashion Week can be found at its web site at www.lgfashionweek.ca.


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Summer is finally here! In celebration, we’ve put together a list of seven brainy books, authored by members of the Dana Alliance for Brain Initiatives (DABI) or prominent neuroscientists, for you to grab on your way to enjoy the warm weather and sunshine:
The Consciousness Instinct: Unraveling the Mystery of How the Brain Makes the Mind by DABI member Michael S. Gazzaniga, Ph.D., Farrar, Straus and Giroux
The Consciousness Instinct is a fun and informative read about a topic that is often written about in ways that are either boring or incomprehensible. Gazzaniga was one of the first scientists in modern times to dare talk about consciousness. He’s been at it for five decades, and keeps coming up with new and interesting ideas. Your consciousness will be raised.
― DABI member Joseph E. LeDoux, Ph.D., New York University
Inventing Ourselves: The Secret Life of the Teenage Brain by DABI member Sarah-Jayne Blakemore, Ph.D., Doubleday
I remember devouring every single book by Judy Blume as a teen, as well as The Secret Diary Of Adrian Mole and A Teenage Health Freak… Now, as the mother of a teen and a pre-teen, I find myself equally hungry for information but from the other side. The teen brain is scientist Blakemore’s specialist subject and her research is celebratory, rather than fearful, of adolescence in all its messy glory. Her new book is a must not only for curious parents but for anyone interested in psychology, creativity, and the developing mind.
― Laura Bailey, Vogue
Chasing Men on Fire: The Story of the Search for a Pain Gene by DABI member Stephen Waxman, M.D., Ph.D., MIT Press
Waxman, who works in basic research and clinical medicine, offers an insider’s account of the global search for a pain gene, beginning in 1966. He intertwines descriptions of cross-disciplinary neuroscience with portraits of scientists, and the struggles of people with conditions such as erythromelalgia, or ‘man-on-fire syndrome’, characterized by burning pain in hands and feet. Structurally, the book is innovative: 11 research papers are interlaced with the stories behind them. It is thus both a boon for researchers and an engrossing read for nonspecialists.
― Tor Wager, Nature
The Healing Self: A Revolutionary New Plan to Supercharge Your Immunity and Stay Well for Life by DABI member Rudolph E. Tanzi, Ph.D., and Deepak Chopra, M.D., Harmony Books
Deepak Chopra and Rudy Tanzi once again effectively harness their scientific training and passionate commitment to advancing well-being in this accessible, life-changing compendium of cutting-edge tools that will extend your health span and improve your sense of meaning, connection, and flourishing. As inspiring as it is informative, The Healing Self shows us how to use our minds to open our awareness and create daily routines to improve our physical and mental health. Bravo to our guides and to you for taking these practical steps toward healing in your life!
― Daniel J. Siegel, MD, Clinical Professor, UCLA School of Medicine
The Strange Order of Things: Life, Feeling, and the Making of Cultures by DABI member Antonio Damasio, M.D., Ph.D., Pantheon Books
In attempts to define what makes us uniquely human, emotions and feelings are often marginalized. These deeply ingrained, often irrational aspects of our behaviour seem destined to be the poor cousins of the rational cognitive functions that enable the formulation of mathematical theorems or operatic scores. In his bold and important book The Strange Order of Things, neuroscientist Antonio Damasio argues that in underestimating the contributions of such ‘lower-level’ brain phenomena to ‘higher-level’ cognitive functions, science might have been missing out on some important biology. Similarly, neuroscience’s emphasis on the origins of language as a shaper of culture might have eclipsed the role of feelings.
― Adrian Woolfson, Nature
Beyond the Self: Conversations between Buddhism and Neuroscience by European Dana Alliance Executive Committee Member Wolf Singer, M.D., Ph.D., and Matthieu Ricard, MIT Press.
Their book is an edited set of conversations Ricard and Singer had over the course of eight years at meetings around the world. This format offers an insight into how these two scholars have, with humor and skepticism, sought to find common ground between the third-person attempt of Western science to understand mental processes objectively, and the first-person introspective approach used over the last two millennia by Tibetan Buddhists. The reader is allowed to eavesdrop as the authors discuss fundamental issues in neuroscience—the nature of consciousness, how emotions are processed in the brain, and how practice changes mental processes—in an engaging and free-flowing way.
― Paul J. Zak, Cerebrum
Cerebrum: Emerging Ideas in Brain Science 2018, edited by Bill Glovin, Dana Press
If you had to choose just one book ever year to keep you informed about recent advances in brain science, you couldn’t make a better choice than Cerebrum. This annual compendium is penned by some of the most accomplished neuroscientists in the world, writing with clarity, authority, and vast experience. The goal is to familiarize the non-specialist reader with the wonders of the human brain. Read any article selected at random, and you will agree that this year’s edition accomplishes this goal with marvelous precision.
― DABI member Richard Restak, M.D., Clinical Professor of Neurology at George Washington Hospital University School of Medicine and Health Sciences and author of 24 books on the brain
(See also: our blog post on the new Cerebrum anthology, written by the editor.)
– Ali Chunovic


The scientific community is digesting the consequences of yesterday’s discovery of water sources on Mars. NASA’s Mars Exploration Program lead scientist Michael Meyer said the latest evidence appears to reveal recent water flow on the surface of the planet. Scientists examined photos sent by Global Surveyor and compared them with those taken seven years ago in the same spot. They observed water had flowed through the 20 new craters they detected recently. NASA say water may have come up from under the surface and flowed long enough to have left traces. However water would quickly freeze at the surface of the cold planet.
Mars has always excited watchers with the possibility it may contain forms of life. 19th century telescopes allowed for detailed study of the planet. Astronomers saw icecaps at the poles and light that changed colour with the seasons. Some saw the grooves in the planet and imagined they were irrigation channels of liquid water. In 1877 Italian astronomer Giovanni Schiaparelli used a new high resolution telescope to produce the first detailed map of Mars. These maps contained features he called canali. The word meant channels but was mistakenly translated into English as canals.
The American self-funded astronomer Percival Lowell was fascinated by Sciaparelli’s theories and spent much of his life studying Mars from his massive observatory at Flagstaff, Arizona. Lowell was convinced the Martian channels were irrigation canals built by a highly intelligent civilisation. His work captured the imagination of the general public and the idea of canals spread under the influence of the science-fiction of Jules Verne and H.G. Wells.
Not everyone was fooled by Lowell’s enthusiasm for the canals. In 1903, the sceptical English astronomer Edward Maunder conducted visual experiments using marked circular disks which led him to the conclusion the canals were an optical illusion. He also said the lack of temperature-equating winds and low mean temperatures meant Mars could not support Earth-like life. It took another sixty years for Maunder to be proved right.
The first flyby by a spacecraft finally dispelled the idea of canals forever. In 1965 Mariner 4 passed over the planet at an altitude of almost 10,000kms above the surface. It took almost eight months to reach its destination and carried a television camera. It returned 22 television pictures which revealed a vast, barren wasteland of craters on a rust-coloured sandy surface. There were no canals. After Mariner 4, scientists accepted the hypothesis that Mars was a dead planet.
Viking 1 was the next Earth expedition to Mars. Launched in 1975, it was planned to land on Mars to celebrate the bicentennial July 4 the following year. However the landing was delayed after the primary site was deemed too rough by NASA. It was followed by Viking 2 three months later. They scooped up samples of the soil and looked for by-products such as oxygen and carbon dioxide. But neither craft found any evidence to support life. However a seismometer aboard Viking 2 did record a marsquake.
Another 20 years would pass before the Pathfinder probe bounced onto the planet with airbags inflated to soften the landing. Aboard the Pathfinder was Mars’ first rover, the Sojourner. Sojourner contained an on-board camera which relay signals back to the base and then on to Earth. It discovered Mars has a crust, mantle, and core, with the heavier elements nearer to the centre. It also encountered evidence of wild weather in the shape of 200 kph winds which had sandblasted rocks.
Meanwhile back on Earth, scientists discovered a Martian meteorite in Antarctica. This rock with the prosaic name of Alan Hills 84001 was scooped off Mars 16 million years ago and after a long trip in space landed on Earth a mere 13,000 years ago. Of most interest were small worm-shaped structures called chondrules the scientists found on the rock. These structures formed billions of years ago when water seeped into the rock. Inside the chondrules were what appeared to be fossilised worms, organic material, and another possibly life-based compound called "magnetite." They declared this might be a form of primitive Martian bacteria, proving life exists on Mars. These findings were later disputed and most scientists now believe the rock has been “contaminated” by its recent life on Earth.
The water discoveries were made by the planet’s most recent visitor. Launched on November 7, 1996, the Mars Global Surveyor is now orbiting Mars. Between 1999 and 2001, it has mapped the entire surface of the planet. It discovered the upper half of the northern hemisphere of Mars was almost entirely flat. Scientists theorised oceans may have flattened it, as the only areas on Earth that are this flat are at the bottoms of deep oceans. In November this year NASA lost contact with the spacecraft after commanding it to adjust its solar panels. The craft’s final gift to NASA was the photos of two craters called Terra Sirenium and Centauri Montes which appear to show the presence of water on Mars within the past seven years.
These images of gullies on Mars show evidence of new flows and deposits. They seem to indicate explosive events in which some form of water burst from crater walls and ran down their slopes. Researchers are talking about a "squirting gun" theory. Mars expert Phil Christensen from Arizona State University said "there is evidence to say, yes, there is subsurface water" but it will take years to prove or disprove”. He went on to say, "ten years ago, Mars scientists were talking about water billions of years ago. Now we can honestly talk about liquid water on the surface today."


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A question came to mind while watching a recent episode of Celebrity Apprentice, but before I explore it, I should make it clear that I don’t like Donald Trump as a person. I don’t know enough about him to make me hate him, but I’m definitely not behind anyone who aims to distract citizens with ridiculous misinformation masquerading as serious inquiry. He’s obviously not a stupid man, yet he attempted to cloud a crystal clear fact about President Obama, instead of using his far-reaching voice to illuminate any number of very real injustices in our world that could benefit from public scrutiny. If one can get past the Donald aspect of it, I do think that Celebrity Apprentice is entertaining at times but mostly helpful to job seekers at any level. It’s valuable to understand what employers want from us, and how to go about thinking that way when necessary, especially in Apprentice’s forum of selling things to the consumer, since the jobs that utilize these skills are the ones in increasing supply. (The hippie in me hates that last sentence, but it’s hard to pay the rent, or the water bill and the property taxes, or eat, without a job.)
I prefer Celebrity Apprentice to the one with the regular folks vying for the job, because it’s easier to see celebrities lose without feeling bad about it. Each of the charities they are competing for is worthy, and just mentioning them gives viewers a chance to learn more about them and consider giving to them if they can, but it’s not sad when one of the celebrities gets fired. I watch this program, almost study it, because as a human being and as a writer, I’m very interested in the differences and similarities there are between us all. This show is like a microcosm of human behavior under pressure, and another great way to people watch and take notes.
The question that came to me, caught me off guard and made me turn off the episode to ponder it. It goes something like this: What makes it hard for some people with lots of money and more so-called sophisticated tastes, to understand when they’re insulting people who work middle class jobs? On the surface, the answer seems obvious, but it didn’t strike me that way in this specific case. I don’t think these people would think to insult those who struggle to eke out a living. If they would never do that, then why tolerate such an insult to anyone? Why didn’t they notice? I think that’s more my question. Here’s what happened:
In a commercial to extol the new wider availability of a specific information product, Meat Loaf came up with the character of a police officer who recovers a stolen vehicle and then goes looking for doughnuts. (You know, the old chestnut about police officers hanging out at the doughnut shop.) This isn’t the most offensive thing anyone could think of by a long shot, I know, but the task was to come up with a commercial that could be successful with the general public. Marlee Matlin, who was the project manager and whose husband is a police officer (which broadens my question), goes along with this idea without hesitation. It’s entirely possible that Star Jones, the other person on their team, would never give this aspect of their commercial a second thought, although I’m sure she would gladly ignore it to benefit her position, even if she had. My own father was a police officer, but even so, I don’t think that all people in any profession or group automatically deserve immunity from being the subject of humor. Still, I immediately understood that while one gives voice to all ideas while creatively brainstorming, this doughnut thing wasn’t going to work for them– unless they wanted to offend someone. A lot of someones.
How could Marlee Matlin have missed this problem? Meat Loaf seems like a sensitive guy (from what I’ve seen on this series) so what was missing in his thought process? Was their cluelessness here more about how and where they make their living? Or was it about personality type? Am I feeding into an increasingly shrill shouting match between social ‘classes’ by merely bringing this up? I hope not, because I think it’s about empathy.
A conversation about this feels important on more than one level, but I prefer to look for answers by digging down deep into an issue and searching for some roots, not just the shoots that grow up out of it. Looking at it that way, I’m inclined to believe that this is more about society’s attitudes toward empathy in general. I think a lot of the backlash against political correctness is about it being more of a band-aid, or a shield, than a careful reflection on the meaning of empathy. Considered on its own, without regard to how one is seen by others, empathy isn’t widely seen as being an important subject. A lot of what we say and do collectively these days, from politics to gossip and what is and isn’t considered news, doesn’t have very much to do with thinking about other people’s feelings before we share our thoughts or do our deeds.
It might help to think of empathy as a muscle. Very often it’s not so much that we as individuals don’t have the capacity for it, as it is that many of us just choose a flow to go along with and then don’t take much time to focus on strengthening this vital part of our core. And we all know what happens when you don’t exercise a muscle. It doesn’t respond so well when you really need it.

domain: sociology


ORDINANCE NO. VII OF 2012
SERVICES OF PAKISTAN (REDRESSAL OF UNDER-REPRESENTATION ORDINANCE, 2012
An Ordinance to address under-representation in the Service of Pakistan
[Gazette of Pakistan, Extraordinary, Part-I, 1st October, 2012]
No. F. 2(1)/2012-Pub.—The following Ordinance promulgated by the President is hereby published for general information :—
WHEREAS clause (1) of Article 27 of the Constitution of the Islamic Republic of Pakistan provides that posts may be reserved for persons belonging to any class or area to secure their adequate representation in the service of Pakistan;
AND WHEREAS under-representation of provinces and areas, namely, Sindh, Balochistan, Federally Administered Tribal Areas and other areas in the service of Pakistan need to be addressed;
AND WHEREAS the National Assembly and the Senate are not in session and the President is satisfied that the circumstances exist which render it necessary to take immediate action;
Now, THEREFORE, in exercise of the powers conferred by clause (I) of Article 89 of the Constitution of the Islamic Republic of Pakistan, the President is pleased to make and promulgate the following Ordinance:–
1. Short title and commencement.—(1) This Ordinance may be called the Services of Pakistan (Redressal of Under-Representation) Ordinance, 2012.
(2) It shall come into force at once.
2. Appointment by transfer.—(1) Notwithstanding anything contained in the Civil Servants Act, 1973 (LXXI of 1973), and any other law for the time being in force, the Federal Government may make appointment by transfer to the post of Senior Joint Secretary (BS-21) and Additional Secretary (BS-21) in the Secretariat Group of regular (BS-21) Provincial Civil Service officers recommended by the respective Provincial Government of Sindh, Balochistan, Administration of the Federally Administered Tribal Areas and such other areas as may be notified by the Federal Government in the official Gazette, who meet the criteria specified in the Schedule to this Ordinance.
(2) The appointment by transfer may take place against posts not exceeding ten per cent of sanctioned posts of Senior Joint Secretary and Additional Secretary (BS-21). The aforesaid percentage posts shall be further sub-divided in the ratio of 19: 6 : 4 for induction of officers of Sindh, Balochistan and Federally Administered Tribal Areas including such other areas as may be notified by the Federal Government in the official Gazette:


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I was obviously really intrigued and felt I had to taste this cake sooner than later. And when I did taste it, I immediately knew I would have to share the recipe here because this cake is just really delicious and you should really try it if you like this type of desserts.
The cake recipe itself as a few variants but I prefer to stick to the kind I got to taste while in France as this is the type of desserts I really enjoy after a meal. Imagine a thin slice of almond pound cake, soft and buttery, moist with the addition of dark rum in and on the cake (on as a set rum icing). This is just perfect as a sweet note after lunch or dinner served with tea and coffee.
I have a little note below with the recipe as to how to substitute the rum for a version with no alcohol in it for a children-friendly gâteau nantais.
Getting to taste a delicious cake such as gâteau nantais is what I really like about my many trips back to France. Even having been raised in France in a family that really loves cooking and trying many recipes, the gastronomy is so diverse in every region that I keep discovering things completely unknown to me (sometimes even in my own region!). And I do love a delicious food discovery! Here is to finding out about many other wonderful French recipes to try.
Had you heard about gâteau nantais before? Is this the type of cakes you like?
Let me know if you end up trying the recipe and if you share a photo on Instagram, tag me @cremedecitron and add #cremedecitronblog_recipe
Ingredients (approximately 12 thin slices)
150g caster sugar
125g salted butter softened at room temperature (plus 5g to butter the cake tin)
100g ground almonds
40g plain flour
40ml dark rum*
For the rum icing
60g icing sugar
20ml dark rum*
1. Preheat the oven to 175˚C.
Butter a 22cm-diameter cake tin and line the bottom with a circle of baking paper (which you should butter too).
2. In a large bowl, cream the softened butter and sugar until light and fluffy (use an electric mixer or whisk to do so - if using the latter, cream the ingredients vigorously). Mix in the ground almonds then the eggs one by one.
3. Fold in the flour with a wooden spoon and mix in 20ml of dark rum.
Transfer the batter into the cake tin and place on the middle shelf of the oven. Bake for 40 to 45 minutes (check that it is cooked through by inserting a skewer or thin knife blade in the centre, it should come out clean).
4. Turn out the cake onto a plate, remove the piece of baking paper and while the cake is upside down, drizzle the remaining dark rum (20ml) over the bottom. Once the liquid is absorbed, delicately turn the cake back onto a wire rack to cool down.
5. Mix the icing sugar and 20ml of dark rum together. Once the cake has cooled down completely, spread the rum icing over the top with a spatula. Let it set.
This cake is better eaten the next day. Once the icing has set, you can cover the cake loosely and keep it in the fridge. It will keep for up to a week.
Serve in thin slices (I get about 12 but you can make them a bit larger if you prefer) with tea and coffee.
Note: * If you intend to serve this cake to children or people who do not consume alcohol, substitute the dark rum for lemon juice or orange blossom water.

domain: food


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Bloggers keep on baking up cupcake flavors I never would've thought of in a million years! Raw food blogger Shannonmarie at Rawdorable has made peanut butter pickle cupcakes, and has the recipe, while Lizzy Mae at Your Cup of Cake created apple cookie dough cupcakes. What do you think of these inventive flavors?
peanut butter pickle!
apple cookie dough!


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Los Angeles, April 11 (IANS) Actress Eva Mendes loves graveyards and old churches as she finds them very peaceful.
Mendes, 39, who will soon be seen in “The Place Beyond The Pines”, started doing it over a decade ago, reports contactmusic.com.
“I love graveyards and old churches, I find them peaceful and quiet,” IO Donna, an Italian magazine, quoted Mendes as saying.
“It all started 15 years ago when I first visited Pere Lachaise in Paris. I don’t pray though, I meditate,” she added.