text:
Republican Congressman Chris Collins arrested on insider trading charges suspends reelection campaign
By: Susan Conte, Xiro Xone News August 8, 2018 Updated: 1:12 PM PT
Rep. Chris Collins (R-NY) was arrested and arraigned on federal charges August 8, in New York City. He plead, “Not guilty,” and was released on $500.000.00 bail.
An unsealed indictment in New York federal court, charged Collins, his son, and the father of the son's girlfriend with conspiracy, securities fraud, wire fraud and making false statements to the FBI.
Prosecutors alleged Collins shared insider information with his son about Innate Immunotherapeutic Limited, a biotechnology company in Sydney, Australia. Collins sat on its board and, was the company's largest shareholder.
According to the indictment, while attending the Congressional Picnic at the White House on June 22, 2017, congressman Collins received an email from the company CEO saying, “A trial of a drug the company developed to treat multiple sclerosis was a clinical failure.”
While still at the picnic and seen on video, he called his son Cameron Collins and spoke for more than, six minutes.
Prosecutors said the son “traded on the inside information and passed it to a third defendant, Stephen Zarsky.” “Their combined trades avoided over $768,000 in losses,” authorities said. They said, “Zarsky traded on it and tipped off at least three others.”
The next morning, according to the indictment, and over a two-day period Collins began selling his shares, to avoid $570,900 in losses before the public was made aware the medical trials had failed.
After the public announcement, the company's stock plunged 92 percent.
A written statement from Democratic House Minority Leader Nancy Pelosi read, “The charges against Collins show the rampant culture of corruption and self-enrichment among Republicans in Washington today."


text:
A dog on a hot warehouse roof, spotted by a rider on a commuter train, has become a source of controversy in Miami, with some animal activists saying he needs to be rescued, and warehouse officials saying he’s only doing his job.
“No animal should live on top of a roof … a scalding hot roof,” said Amy Roman Restucci with Abandoned Dogs of the Everglades, who posted an account about the dog on Facebook.
“We do not know why this dog is up there, but we thought of a few different possible scenarios, and can not think of one that would be acceptable for this dog to be there. Not knowing the circumstances, we are torn as to how and go about helping this dog without possibly putting him in more danger or dooming him to death by animal control if called.
“… One thing we do know is that this is NO PLACE FOR A DOG!! The temperatures on that roof alone can cause this dog a heat stroke. We want the dog removed from that roof immediately!
Local 10 flew its helicopter above the building, spotting the dog on the roof. There are some shaded areas, and a doghouse, and several bowls nearby, it reported.
Neither the Miami Fire Department or the Miami-Dade County animal control department planned to get involved, saying it’s not against the law to keep a dog outside, as long as it has food, water, and shelter.
Raudel Hernandez, a worker for G&G Produce, told Local 10 that the dog on the roof, named Burro, is one of two that serve to protec the building from thieves. Burglars have broken in three times, stealing copper wire from the air conditioning units.
A petition to “save the dog on the roof” has been posted on Change.org
Posted by jwoestendiek August 3rd, 2012 under Muttsblog.
Tags: abandoned dogs of the everglades, amy roman restucci, animal cruelty, animal welfare, burro, copper, dade county, dog, dog on roof, florida, fruit, g & g produce, guard dog, health, heat, heat stroke, miami, petition, produce, protection, raudel hernandez, rescue, roof, safety, save, security, thefts, warehouse

domain: pet


text:
Consultants hosting AF trainees within the speciality of psychiatry.
Dr Mohammed Abbas
Motives of suicidal behaviour and testing the effectiveness a new training model of suicidal/self harming risk assessment and management. I developed a new model of case formulation in Psychiatry and tested its effectiveness on the case formulation skills of psychiatric trainees using RCT. A similar approach could be used with medical students (this type of research could be seen as medical education type).
- Contact Dr Mohammed Abbas
Professor Liz Anderson
I am a regional, national and international leader of interprofessional education aligned to team working and patient safety. I have a range of research projects within medical educational exploring interprofessional simulations, the need for reflection using Portfolios and designing and piloting new learning possibilities in practice, recently bringing together pharmacists and medical students.
- Contact Professor Liz Anderson
Dr Natalie Armstrong
The SAPPHIRE (Social Science Applied to Healthcare Improvement Research) Group in the department of Health Sciences uses social science theory and methods to undertake research and evaluation in order to improve the quality and safety of healthcare. A developing area of interest in the group is around overdiagnosis and overtreatment, which occur when a diagnosis is ‘correct’ according to current standards but the diagnosis or associated treatment has a low probability of benefiting the patient, and may instead be harmful. We would welcome Academic Foundation doctors keen to explore this area further either in general terms or as it relates to a particular clinical area.
- Contact Dr Natalie Armstrong
Dr Clare Oakley
St. Andrew’s Healthcare is the UK’s leading charity providing specialist care for the NHS and we offer in-depth expertise in trauma, personality disorder, psychosis, autism, learning disability, brain injury and dementia. St Andrew’s Academic Department is currently collaborating with several different Universities on a range of research projects. Research themes include risk assessment, the use of technology in patient care, physical activity and metabolic syndrome.
- Contact Dr Clare Oakley
Professor Gavin Murphy
As the Director of the University’s Clinical Trials Unit, I oversee a portfolio of clinical trials spanning multiple clinical areas (including cardiovascular, respiratory, diabetes, mental health, cancer, dermatology and public health) and all stages of development, from initial idea to final publication. Your placement would thus allow for both breadth and depth of exposure.
- Contact Professor Gavin Murphy
Dr Carolyn Tarrant
The SAPPHIRE (Social Science Applied to Healthcare Improvement Research) Group has expertise in qualitative methods and health care improvement, with particular interests in acute care, maternity care, healthcare associated infections, and measurement for improvement. A qualitative project would be available to explore junior doctors' experiences of working in acute care at weekends, in relation to their role and professional development; we would also be happy to discuss other possible research topics.
- Contact Dr Carolyn Tarrant
My primary research interest relates to the prevalence of autism within inpatient psychiatric settings, as well as the mental and physical comorbidities of this patient group, with which I work closely with Professor's Traolach Brugha and Guiqing Yao. I am also interested in psychiatric epidemiology more generally, as well as neuro-developmental disorders and intellectual disability.
- Contact Sam Tromans

domain: medical


text:
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domain: design


text:
This is a standard futuristic spacefaring type of story. Humans have, as they tend to do in these stories, spread across the known universe and it’s been so long since the original diaspora that memories of Terra have all but faded; only myth remains. Other species abound and the Human Commonwealth tries to bring a semblance of order and law to the universe. First contact with a new species has protocols…
Esen-alit-Quar is a very special individual; she is one of the last five of her kind and she is on her first assignment to observe a new species. But Esen and her web-kin are not of the Commonwealth; their mission is simply to observe and preserve information. Esen and her web-kin are shifters; the only ones in the universe who can change their form. This is, of course, the way they can safely observe other forms of life they become them. When Esen’s mission is compromised in the first year by a Commonwealth First Contact Team, she knows the Eldest is not going to be forgiving. But she really didn’t have a choice: it was ingrained in her that all life is to be protected. And once she figured out that the planetary authorities were well aware of extraterrestrial life and they intended to completely destroy all trace of the First Contact Team as they had been doing for a very long time, to keep their population ignorant she had to do all she could to save the last surviving human of the landing party, Paul Ragem. Also ingrained in her training was the rule that she must never, never show her true form to anyone.
Paul Ragem happens to be, of all things, a sort of exobiologist a specialist in alien species. But Esen defies all he knows and he’s desperate to understand just what she is beyond being his savior.
While Esen and Paul are doing their best to survive and escape; there’s another creature of interest a monster in space bringing death to mining colonies, ships and even whole planets. And the monster is hunting web-kin! It falls to Esen to stop the creature before it kills the only family she knows.
And, finally, there is Kearn. Kearn was a specialist on the First Contact Team and ended up as Acting Captain since the Captain was a casualty in their last mission. Kearn is a bit OCD and feels most comfortable when things are predictable and understandable. Esen is, by her very nature, neither of those things. And things get really complicated when Kearn observes the monster and through a misunderstanding believes the monster is Esen. His dogged perseverance to track her down and destroy her is almost admirable…unless you happen to be the trackee.
The flow of the chapters alternates between Esen and Paul in flashbacks, then Esen reporting to her web-kin and particularly the Eldest Assimilator, and then Kearn, with very small descriptions of the progress of the monster. It was a captivating flow that kept all my interest through to the end. The characters were very well-presented and the plot was great. A good sci-fi read always has a mystery at its center and this one’s a doozy. I loved Esen and I admire how the author was able to…hide…certain aspects of Esen from her readers that will be very significant in the next book. It’s all in the last page. ~~ Catherine Book
For more titles in this series click here
For more books by Jule Czerneda click here

domain: literature


A BUG is actually an error of a program or software or a computer, that flaws through the system and cause malfunctioning of the device. Thus this makes the device unstable due to the malfunction of the device.
A Bug basically occurs due to the mistakes of coding made by the programmer. If the programmer inserts incorrect code during the programming or compiling code, then this results in the appearance of the bug.
Compiling codes can be hard and sometimes it is very often to make mistakes in programming by the programmer. But the Bug can be fixed with a software update.
There are many Bugs that are uncountable or perhaps countable.
Security Related Bugs
Code Compiling Bugs
Malicious Code Bug
Well, These are the Category of it. Inside them, you can find countless Bugs.
Bugs can cause any problem. It depends on the code what is programmed to do and the missing code can interrupt the stability of the device. If third-party code is injected into the system then this can also cause the appearance of the Bug if the code of the third party does match the system’s code.
Bugs can literally destroy your device’s functioning if malicious codes are injected. It can even give hackers remote access to your device using third-party code injection. This means a Bug doesn’t have to be an error of the programming. It could also be a third party’s code to infect the device using its code to malfunction or to gain access to the device.
Yes, the bugs can be debugged by the analysis of the existing code, if errors are found.
The bugs can be debugged by the Developers. The developer has to search find the missing, broken, or incorrect code to fix it. If the system is infected by the third party’s code then the developer has to remove it by updating the security patch. This means blocking a third-party’s code by closing the backdoor system injection.
There are many other processes to debug the Bug.
So, bugs can appear on any device. Bugs don’t have to be an error it could also be malicious code injected into the device software. Bugs can be debugged by the developers or the programmer by updating security patches and missing or broken codes.
Did you liked the article, or was it helpful? Let us know your opinion by voting on 'Yes' or 'No'. Provide your feedback as well if you would like!


text:
1 edition of immune consequences of trauma, shock, and sepsis found in the catalog.
immune consequences of trauma, shock, and sepsis
|Statement||E. Faist, A.E. Baue, F.W. Schildberg (eds.).|
|Contributions||Baue, Arthur., Faist, E., Schildberg, F. W., International Congress on the Immune Consequences of Trauma, Shock, and Sepsis--Mechanisms and Therapeutic Approaches (3rd : 1994 : Munich, Germany)|
|LC Classifications||RD93 I53 1996|
|The Physical Object|
|ISBN 10||3928057758, 3928057766, 3931660141|
Additionally, reactivation of herpes simplex virus Immune consequences of trauma and cytomegalovirus CMV may have some clinical relevance in critically ill patients. Septic shock may be regarded as a stage of SIRS Systemic Inflammatory Response And sepsis bookin which sepsis, severe sepsis and multiple organ dysfunction syndrome MODS represent different stages of a pathophysiological process. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: Table 2 Characteristics of clinically apparent infections during the previous year Full size table Exclusion of current acute infections Standard inflammatory markers were determined to screen for current infectious diseases. On the other hand, systemic inflammatory response syndrome SIRS occurs in people without the presence of infection, for example, in those with burnspolytraumaor the initial state in pancreatitis and chemical pneumonitis. Where pneumonia has been found more frequently at PM than was appreciated ante-mortem, the extent of pulmonary involvement was not quantified [ 73 ].
In a immune consequences of trauma sulphate sodium-induced colitis model, mice deficient in IL-1RI signaling showed increased susceptibility to and failed to mount a protective type I interferon response after Toll-like receptor And sepsis book 9 ligand administration [ 4 ]. Critical Decisions April Trauma Emergency physicians are well acquainted with trauma. Beneficial or deleterious roles of the same leukocyte subset have been reported depending upon the experimental model. An impaired immune response as one sequelae of previous sepsis is believed to be a major contributing factor in these delayed deaths [ 1622 ]. In this review, we argue against the promulgation of what we believe is a misleading perception of sepsis inducing secondary immunosuppression.
Approximately Dectinpositive cells were more frequent but Dectin-1 density was not affected in the sepsis survivors. There are also changes in complement components. Next, ensure a complete examination is done. For example, in the condition of abdominal or brain trauma, the kinetics of biomarkers can be changed.
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Diagnosis is often made with a blood test. Shock should be suspected in those poorly responding to resuscitation with fluids shock vasopressors. In the future, comprehensive studies need to test the correlation between the reasons alterations of the immune cells and the effects quality of life and survival.
By some estimates, severe sepsis or septic shock strikes nearly 1 million Americans each year. The diagnostic challenge is present because sepsis is defined using SIRS criteria, but it is not always initially known which patients are simply SIRS without infection, while others have actual sepsis.
If the patients die with infectious foci and altered immune status, it does not mean they die because of them. It causes symptoms such as fever, chills, rapid breathing, and confusion.
In our study, we found contrary results for PD-1 in sepsis survivors in the long term Fig. After evaluation of possible exclusion criteria, written informed consent was collected and individuals were enrolled in the study.
However, distinct differences were found in prescribed medications e. Individualized medicine does not stop at the hospital door and therefore, we need to reconsider what comes after acute critical care.
Decreased surface HLA-DR expression on monocytes is a reliable surrogate marker shock global immunosuppression and its value predicts mortality and development of nosocomial infection in patients suffering from sepsis [ 34 — 39 ].
In our study, patients who survived an episode of sepsis had alterations in monocyte surface expression of pattern recognition receptors Fig.
All patients identified were contacted by mail. In the gastrointestinal tractincreased permeability of the mucosa alters the microflora, causing mucosal bleeding and paralytic ileus. In general, local hyperinflammation due to host defenses against invading pathogens should be beneficial.
The scientific community needs to reconsider models used to validate therapeutic approaches. To our knowledge studies investigating this phenomenon are rare, especially in humans. The utility of base immune consequences of trauma and arterial lactate in and sepsis book major from minor injury in trauma patients with normal vital signs.
Immune consequences of trauma murine responses do not resemble human processes, maybe other species, like the pig, should be preferred. Ensuring adequate nutrition—preferably by immune consequences of trauma feedingbut if necessary, by parenteral nutrition —is important during prolonged illness.
Overgrowth of antibiotic-resistant microorganisms shock barrier defects predispose them to secondary infections, even without overt defects in their immune defenses [ 70 ]. However, others, such as CRP, though many studies have been performed on it, show no predictive power for trauma patients.
Was there an arrhythmia? The most notable and coherent effect was seen for TLR5, which is a fundamental player in pathogen-associated molecular pattern recognition bacterial flagellin and therefore an activator of innate immunity.
In vivo, TNF induces extra-adrenal production of immunoregulatory glucocorticoids in the intestinal mucosa during acute intestinal inflammation [ 3 ]. Pneumonia is frequently present in patients in whom supportive care is withdrawn due to failure to thrive.
Although no adverse effects were reported, it is worth recalling a case report of a patient who developed a fatal adult respiratory distress syndrome after GM-CSF treatment [ 77 ].
But sepsis is one of the top 10 causes of disease-related death in the United States. Immune cells not only recognise pathogen-associated molecular patterns, but also damage-associated molecular patterns from damaged tissues.
The current MO experiments focus on the tolerogenic capacity of patients' DC in mediating their immunodepression.If something does not seem right with the clinical picture, consider any missing pieces and consider sepsis.
Sepsis after Multiple Trauma. Sepsis is a challenging complication after trauma. One study evaluated the incidence of sepsis in trauma over four periods, finding % in% in% inand % in Jul 11, · Septic shock is the result of an infection, and causes drastic changes in the body.
It occurs when you experience a significant drop in blood pressure. This can lead to respiratory or heart.
Jul 28, · Injury severity, mechanism of injury, number of injuries, hypotension on admission, and other injury characteristics are factors associated with post-traumatic sepsis. Immune consequences of trauma can cause and sepsis book in the immune system by depressing the humoral and cell-mediated systems.
After major trauma, the function of lymphocytes is magicechomusic.com by: Mar 24, · A relative immunosuppression is observed in pdf after sepsis, pdf, burns, or any severe insults. It is currently proposed that selected patients will benefit from treatment aimed at boosting their immune systems.
However, the host immune response needs to be considered in context with pathogen-type, timing, and mainly tissue magicechomusic.com by: Free 2-day shipping. Buy Immune Consequences of Trauma, Shock, and Sepsis: Mechanisms and Therapeutic Approaches at magicechomusic.comnd: Eugen Faist.Buy Immune Consequences of Trauma, Shock, and Sepsis: Ebook and Therapeutic Approaches by E.
Faist, J. Ninnemann, D. Green (ISBN: ) from Amazon's Book Store. Everyday low prices and free delivery on eligible magicechomusic.com: E.
Faist, J. Ninnemann.

domain: biology


text:
Though their use of broadband is slightly lower, online Hispanics in the US are 211% more likely to download digital content than the average US adult internet user, and they also are significantly heavier users of cell-phone features, according to (pdf) a study by Scarborough Research.
The study finds that 42% of Hispanic internet users have downloaded some form of digital content during the past 30 days, compared with 35% of the total internet population. Music is the top download category for both Hispanics and the total online population. Almost one-third (32%) of Hispanic internet users and almost one-quarter (24%) of all internet users have downloaded music during the past month.
Broadband Adoption Mirrors Total Population
Broadband use among Hispanics is a few percentage points lower than that of the total online population, Scarborough found.? However, Hispanics’ rate of adoption in recent years has mirrored that of the total US population. Currently, 68% of Hispanic internet users have a broadband connection in their household (up from 13% in 2002), vs. 71% of US internet users who currently have broadband at home (up from 15% in 2002).
“Increased high-speed internet access among Hispanics is opening the door for online businesses to establish brand loyalty with this consumer group,” said Gary Meo, SVP of digital media services, Scarborough Research. “Offering Hispanics new and creative ways to interact with a brand online – particularly via downloaded digital content – could go a long way in successfully marketing to the Hispanic adult.”
Internet Use Reaches Critical Mass
The study also found that Hispanic internet usage overall has reached a critical mass. The majority (54%) of Hispanics are now online, and internet access among Hispanic adults has increased 13% since 2004. In contrast, internet access by all consumers nationally grew only 8% during this time period.
Cell-Phone Feature Use Higher than Average
Hispanic cellular users are on par with or slightly above other US cellular subscribers in feature usage across most categories. The most popular features include text messaging, which is used by 55% of Hispanics (vs. 48% of total cellular subscribers); picture taking, used by 53% of Hispanics (vs. 46% of total cellular subscribers) and downloading ring tones, done by 32% of Hispanics (vs. 29% of total cellular subscribers).
Geographic Variations and Usage Patterns
The study also examines 13 local US markets with higher-than-average concentrations of Hispanic adults. Research reveals distinctive internet usage patterns and local variations. Some key geographic differences:
- Miami is the top Hispanic market for broadband penetration. More than three-quarters (76%) of Hispanic internet Users in Miami have broadband at home.
- El Paso, Dallas, Fresno, CA, and Harlingen, Tex., are the markets in which Hispanic residents are least likely to have a broadband connection.
- Phoenix is the leading local market for Hispanics who download digital content. Some 60% of that city’s Hispanic internet users downloaded digital content during the past month.
- El Paso, Miami and Dallas are the markets where Hispanic internet users are least likely to download digital content.
- Hispanics in New York and San Francisco are likely to spend the most online, while those in El Paso and Harlingen spend the least.
- San Francisco has one of the lowest Hispanic internet access growth rates in the country (4% growth from 2004-2008), but it has one of the highest Hispanic broadband penetration rates and Hispanic downloading rates.
About the research: Scarborough’s full report, “The Power of the Hispanic Consumer Online” (pdf) contains details on internet spending, mobile device usage, and overall Internet usage among Hispanics. It also compares and contrasts internet users across 13 Hispanic local markets. The data in the report is from Scarborough’s USA+ study, as well as select local market studies.

domain: news


An engineering and design firm received approval for $263,000 worth of major Galt street projects Tuesday.
Roseville-based Omni-Means, Ltd. will take the lead on the Twin Cities Road reconstruction, which could begin sooner than anticipated.
The largest change will be widening the road between Bergeron Road and east of Fermoy Way in anticipation of Walmart’s opening next year.
Other improvements on Twin Cities Road will include installing a roundabout at Highway 99, and adding lanes to accommodate both the increased traffic and necessary left turns into the future Walmart and other businesses.
The roundabout project is expected to start in the spring and be completed in fall 2013. Omni-Means has designed other area roundabouts, including one at the Roseville Galleria in 2010.
All of the Twin Cities Road improvements will be paid for through a combination of transportation funds and a fee agreement with Walmart that has not yet been finalized.
“We’re essentially robbing Peter to pay Paul until they pay up,” Public Works director Steven Winkler said at Tuesday’s meeting.
City manager Jason Behrmann said Walmart has already indicated it is willing to pay for the improvements. Omni-Means, Ltd. will be paid $247,000 for the engineering and design work.
A separate $16,000 contract with Omni-Means was also approved unanimously at Tuesday’s City Council meeting for landscape modifications at the Central Galt Interchange.
The scope of the project includes landscaping along both A and C streets, and working with the California Department of Transportation to complete work started nearly four years ago but halted until the interchange was near completion, according to Winkler.
That project is currently six months ahead of schedule and paving will soon begin.
Contact reporter Jennifer Bonnett at email@example.com.


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text:
A flat in a trendy residential neighbourhood 15min walk away from the downtown, central train station and also Florenc bus terminal.
There is a (PHONE NUMBER HIDDEN) private terrace with garden furniture ideal for BBQs and smokers. Netflix on TV, fast wi-fi, comfortable beds, quality towels and bedding.
A 1-bed flat with a large living room and 20m2 terrace.
Interaktion mit Gästen
If you need help with organising your trip in Prague or the Czech Republic, I will be happy to help you (I do that professionally too).
No smoking in the flat, only allowed on the terrace.

domain: travel


Without a doubt, the Ducati Diavel 1260 is the most polarizing motorcycle that I ever rode. Never before I got so many reactions to the design of a test bike. “Ugliest Ducati ever,” I heard. But the haters were easily outnumbered by the fans. I saw a lot of love for the Diavel. One driver even payed more attention to my bike than to the road.
The Diavel’s distinct design is a real eye-catcher. A long and low body, with a muscular front and a striking rear: no fender, just a license plate holder which fortunately prevents a wet back during rain rides. Thanks to the single-sided swing arm on the left and the short exhaust, you have a good view of the impressive rear wheel.
On photo the Diavel couldn’t really convince me, but in real life its design won my heart easily. The finish is outstanding. Even if its looks aren’t for you, you can’t deny that the designers from Bologna put a lot of love into them. Just look at fine details such as the panels in brushed steel, the beautiful indicator lights on the front or the backlit buttons on the handlebars (just a pity that the lettering on those buttons isn’t transparent, so it doesn’t light up in the dark).
In 2011 the Diavel was introduced, and got a major update for model year 2019 to make it easier to steer. New engine (the 1262 cc Testastretta twin with variable valve timing that we know from the Multistrada), adjusted geometry with a shorter wheelbase, a reduced rake and a decreased trail, a higher seat, a weight reduction of 10 kg and more centrally placed foot pegs.
Easy steering isn’t something I expected from the Diavel. With a full tank it weighs more than 240 kg, and on top of that there are the vast rear tire and the not exactly short wheelbase. In addition, the term “power cruiser” (the category in which this Ducati is housed) sounds more like fast-on-the-straights than light-footed-through-the-corners.
But the power cruiser emblem doesn’t really fit the bike. There’s indeed plenty of power, but calling the Diavel a cruiser? You must be joking. Firstly because of the sitting position. It’s not relaxed leaning backwards, with the feet forward. It’s active: slightly bent forward, with the legs in an acceptable angle. By the way, if you’d like a more cruiser-like position: check out the xDiavel.
The adjustable suspension sits nicely between hard (for tight cornering) and soft (to filter out bad road surfaces). In addition, and despite the considerable weight, the Diavel enters corners remarkably easy. The result: the bike offers very good road handling and is remarkably playful for its size, a second argument why you shouldn’t call it a cruiser. Still it prefers fast long corners, in tight turns it requires some extra input.
Next to being playful, the Diavel is also terribly powerful. What else would you expect from that massive twin engine that delivers 159 hp (at 9,500 rpm) and 129 Nm (at 7,500 rpm)? The bottom range isn’t the engine’s favorite, but from around 5,000 rpm it pulls harder and harder, to finish off with an extra energy shot right before the limiter. Big fun.
Despite that devilish power, the Diavel is still perfectly manageable. It has a good throttle response, efficient brakes and a bunch of electronics such as cornering ABS and traction control. The sensitivity of the latter depends on the riding mode you choose. There are three: Sport, Touring and Urban. Urban limits the engine to 100 hp, Sport reacts quite fiercely to the throttle, but all in all, this Italian stallion remains civilized. For example the center of Brussels during peak hour wasn’t a problem with the Sport mode. In Touring mode it behaves less extreme, but not less impressive.
The cruise control is also standard and very welcome, because the Diavel isn’t a very comfy bike. After all, you’re riding a kind of naked bike with zero wind protection. At first sight, the seat looks like it doesn’t offer any room to move around, but it actually has just enough space and good grip. And yes, there’s room for a pillion too.
The display is remarkably low-profile. It is positioned in such a way that you don’t see it when you stand in front of the bike, so it looks like the Diavel doesn’t have a display. If you hop on the seat, there is little to see on and around the handlebars, resulting in a surprisingly open view on the road. Despite its tiny format (3.5″), the display packs a lot of info. Some info is very small, but because it concerns secondary information, it doesn’t bother.
The six-speed box requires clear input. It dares to ignore subtle shifting instructions, and sometimes it misinterprets them, so you end up in the void between two gears.
A void in your wallet could also occur, because the Diavel isn’t exactly cheap: from $20,295 on. If that price-tag isn’t a problem, why don’t you consider the Diavel S? About $3.000 more expensive, but also with more treats. Among other things: better brakes (Brembo M50 instead of Brembo M4.32), Öhlins front and rear suspension and a quick shifter.
The Ducati Diavel 1260 is not your average bike. You might think it’s a kind of cruiser, but at the same time it looks extremely brutal and powerful, which of course it is. Or did you expect otherwise from such an impressive two-cylinder? What you might not expect is that the Diavel is also a very pleasant cornering machine. Its handling is a lot lighter and easier than its size and weight suggest, and it has an excellent road holding. Fortunately, it also has enough electronics to intervene should you become over-enthusiastic. Only its prize will have a hard time making you enthusiastic. But if you go for it, you do have a unique bike with which you’ll easily leave the pack behind you.
Photography: Kenny VH
+ Beautiful design
+ Crazy engine
+ Doesn’t intimidate despite its power
+ Remarkably light steering behavior
– High price
– If I really have to come up with another downside, I’d prefer a more refined gearbox
Type: Ducati Testastretta DVT 1262, L-Twin cylinder, 4 valves per cylinder, Dual Spark, Liquid cooled, Desmodromic Variable Timing
Displacement: 1,262 cc
Bore x stroke: 106 x 71,5 mm
Compression ratio: 13,0 : 1
Power: 117 kW (159 hp) at 9,500 rpm
Torque: 129 Nm at 7,500 rpm
Fuel injection: Bosch electronic fuel injection system, eq 56 mm elliptical throttle bodies with Ride-by-Wire system
Exhaust: Stainless steel pipes and single muffler with twin tail pipes, Catalytic converter and 2 lambda probes
Gearbox: 6 speed
Primary drive: Straight cut gears, ratio 1,84:1
Final drive: Chain, Front sprocket Z15, Rear sprocket Z43
Clutch: Slipper ans self-servo wet multiplate clutch with hydraulic control
Frame: Tubular steel trellis frame
Front suspension: 50 mm adjustable usd fork
Rear suspension: Monoshock, preload and rebound adjustable, Aluminium casted single-sided swingarm
Rear Wheel: Light alloy casted 8,0”x17”
Front Tyre: Pirelli Diablo Rosso III 120/70 ZR17
Rear Tyre: Pirelli Diablo Rosso III 240/45 ZR17
Wheel Travel: 120 mm front / 130 mm rear
Front brake: 2x 320 mm semi-floating discs, Radially mounted Brembo monoblox 4-piston M4,32 callipers, PR18/19 radial master cylinder, Bosch Cornering ABS Evo
Rear Brake: 265 mm disc, 2-piston Brembo floating calliper, Bosch Cornering ABS Evo
Dimensions and weights
Dry weight: 218 kg
Kerb weight: 244 kg
Wet weight (no fuel): 233 kg
Seat height: 780 mm
Wheelbase: 1,600 mm
Trail: 120 mm
Fuel Tank Capacity: 17 l
Number of seats: 2
Safety equipment: Ducati Safety Pack (Bosch Cornering ABS Evo, Ducati Traction Control EVO DTC), Riding Modes, Power Modes, Ducati Wheelie Control Evo (DWC)
Standard equipment: Cruise control, Ducati Power Launch Evo (DPL), Hands-Free, Backlit handlebar switches, 3,5” TFT colour display and dedicated warning light display, Full LED lighting system, Self cancelling turn indicators
Ready for: Ducati Quick Sift up/down (DQS), Ducati Multimedia System (DMS), Antitheft system


text:
MedlinePlus is an online health information resource for patients and their families and friends. It is a service of the National Library of Medicine (NLM), the world's largest medical library, which is part of the National Institutes of Health (NIH).
PubMed citations and abstracts include the fields of biomedicine and health, covering portions of the life sciences, behavioral sciences, chemical sciences, and bioengineering. PubMed citations often include links to the full-text article on the publishers' Web sites and/or in PubMed Central and the Bookshelf. [MEDLINE is the largest subset of PubMed. You may limit your PubMed search retrieval to MEDLINE citations by restricting your search to the MeSH controlled vocabulary or by using the Journal Categories filter called MEDLINE.]
Additional health and wellness articles may be found in these databases:
Provides full text articles on complementary, holistic and integrated approaches to health care and wellness for more than 180 international, and often peer-reviewed journals and reports. In addition, there are hundreds of pamphlets, booklets, special reports, original research and book excerpts. Features indexing and abstracts going back as far as 1984, and full text going back as far as 1990.
Provides access to nearly 80 full text, consumer health magazines with information on many health topics including the medical sciences, food sciences and nutrition, childcare, sports medicine and general health.
Provides nearly 550 scholarly full text journals focusing on many medical disciplines. It also features the AHFS Consumer Medication Information, which covers 1,300 generic drug patient education sheets with more than 4,700 brand names.
Professional articles related to physical education may be found here:
Indexes journal articles and other documents in the field of education and is the premier database for education professionals. Journal articles are assigned identifier numbers that begin EJ, and documents are assigned identifiers that begin with ED. Many of the full articles are available in the search results.
The following databases include all subject areas so may provide additional articles for exercise science. Both professional and consumer articles are included:
Indexes and abstracts journal articles on a broad range of topics and provides the complete text (text and graphics) of many of the articles it indexes. Aimed at undergraduates, it provides scholarly journal articles along with articles from popular, technical/trade, and substantial news sources
Indexes and abstracts articles in magazines, journals & newspapers on a broad range of subjects and provides the complete (text and graphics) of many of the articles. Aimed at undergraduates, it provides scholarly journal articles along with articles from popular, technical/trade, and substantial news sources.
Find books and more
The following research database will help you find books (print and online) and videos.
This is an index to items that the Mundt Library owns or to which the Mundt Library subscribes. Use this database to find books, e-ebooks, videos, CDs and DVDs, and print magazines and journals. If off-campus, log in with DSU ID and password.

domain: library


text:
Jesse.boyle's Instagram Audience Analytics and Demographics
Free Promotion Count
Paid Campaign Count
Get Our Influencer Rate Card Today!
A brand new way for you to compare the rates of influencers across the world.Learn More
PROFILE OVERVIEW OF JESSE.BOYLE
Average engagement rate on the posts is around 6.50%. The average number of likes per post is 1934 and the average number of comments is 73.
40.58% of the followers that engaged with jesse.boyle regularly are from Australia, followed by United States at 11.59% and Kenya at 10.14%. In summary, the top 5 countries of jesse.boyle's posts engager are coming from Australia, United States, Kenya, United Kingdom, Cameroon.
Jesse.boyle loves posting about Film, Music & Books, Humor.
Check jesse.boyle's audience demography. This analytics report shows jesse.boyle's audience demographic percentage for key statistic like number of followers, average engagement rate, topic of interests, top-5 countries, core gender and so forth.
GENDER OF ENGAGERS FOR JESSE.BOYLE
AUDIENCE COUNTRIES OF JESSE.BOYLE
- Australia 40.58 %
- United States 11.59 %
- Kenya 10.14 %
- United Kingdom 7.25 %
- Cameroon 4.35 %
me patiently waiting to play OUT THE ROOF and MOLLY live 😛 which song u must excited for when we back on the road ??
DENIM CREW MORNING WALKIES 😎🤘🏼
everyone, meet Rocky 🖤🥰
BRAZIL 🇧🇷 ooo gonna be fun
Braaaziiiillllll 🇧🇷 ya boiz be back in 2021 // Eu mal posso esperar para conhecer vocês!
always been obsessed with watching it, now I’m even more obsessed with doin it 🥊 can’t wait to be ready to compete 🤤
enjoy is fukin bizarre word the more you say it
Happy Aussie birthday bby boi! Some classic cesse pics since the world is fucked and we are a big ol ocean a part. I love ya, I miss ya, and yes I rly wanna kiss ya. Hope you have an amazing day and I can’t wait to make more memories with me boi 💕 @clintoncave MWAH
PEOPLE ALSO VIEWED
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domain: geography


text:
Little Penguin has problems: his beak is cold; there's snow everywhere; the water smells salty; he waddles; he looks the same as everybody else. No - it's not easy being a penguin!
In this hilarious first collaboration from Jory John and Lane Smith, a penguin levels with human readers about what penguin life is really like ... and it isn't all fun and games! Have you ever considered running away to Antarctica? Of course you have! Because it's a land free of worries and responsibilities! Think again, my friend. This penguin has come to tell you that his life down there is no picnic. For starters, it is FREEZING. Also, penguins have loads of natural predators. Plus, can you imagine trying to find your mum in a big crowd of identical penguins? This book is sure to tickle all funny bones, and will elicit appreciative sighs from the adults reading it aloud, too!
Jory John is the author of the picture books I Will Chomp You! and Quit Calling Me a Monster!, both illustrated by Bob Shea, and Goodnight Already! and I Love You Already!, illustrated by Benji Davies. He is the co-author of the New York Times bestselling novel, The Terrible Two, and the bestseller All My Friends Are Dead, among many other books. He lives in San Francisco, USA. Find Jory online at www.joryjohn.com and on Twitter as @joryjohn.
Lane Smith has written and illustrated a number of novels and picture books for children, including the two Caldecott Honor titles, Grandpa Green and The Stinky Cheese Man and Other Fairly Stupid Stories. He was a 2014 recipient of a Society of Illustrators Lifetime Achievement Award and was named an Honor Artist by the Eric Carle Museum. He lives with his wife, book designer Molly Leach, in rural Connecticut, USA. Find Lane online at www.lanesmithbooks.com.
This book exudes humour both verbal and visual but put together the result is sheer gigglesome comedic delight at every turn of the page.
Red Reading Hub
"Ever thought you had problems? Try being a Penguin! There's too much snow, it's too cold, the sea has too many dangerous creatures in it, everyone looks the same. In fact, there seems to be no end to the problems facing a young penguin! But all is not as completely hopeless it seems. A wise walrus offers good advice and Penguin begins to feel that the world is not quite as hopeless as he had thought. Lane Smith's stylish illustrations brilliantly capture universal emotions of loneliness, isolation and the widespread feeling of being 'different'."
Julia Eccleshare Pick of the Month November 2016, LoveReading
"[…] may well appeal to young adults more than it does to junior infants but is fiendishly cute all the same."
The Irish Times
"[…] hilarious […] an Antarctic take on A Christmas Carol featuring a dissatisfied penguin and a wise walrus who sets him right."
A sweet and tongue-in-cheek story about remembering all the good things in our lives and trying not to worry too much, this stylish picture book has a Jon Klassen feel to its language and a positive message for little worriers.


text:
You take anastrozole as a tablet once a day.
How Anastrozole Is Given:
You can get hot flushes. Talk to your doctor before starting any exercise program Avoid smoking and limit your alcohol consumption Talk to your doctor to see if you need to have a BMD test to help determine if you are at risk for osteoporosis.
Find out about anastrozole, how you have it and other important information. Call freephone or email us. There are a few things you can do to help with hot flashes. What happens if I miss a dose Arimidex?
What Anastrozole Is Used For:
Your care team can help you find these resources, if they are available. Vaginal Dryness Vaginal dryness and related painful intercourse is one of the more common side effects of cancer therapy in women. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
Possible Side Effects There are a number of things you can do to manage the side effects of anastrozole. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Call your doctor at once if you have a serious side effect such as: How to Take Anastrozole Anastrozole is a tablet that is taken by mouth.
This drug may make you dizzy. Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect.
You can get vaginal moisturisers lubricants from your nurse or from the pharmacist. Hypercalcemia with or without an increase in parathyroid hormone [ Ref ]. Breast cancer Secondary breast cancer Breast cancer in men.
This drug can make you feel sleepy. Stevens-Johnson syndrome [ Ref ].
Myalgia ; arthralgia; pathological fracture. Anastrozole may also be used for purposes not listed in this medication guide. Identification color white shape round imprint DB02 This medicine is a white, round, film-coated, tablet imprinted with "DB02". Osteosarcoma in Pediatrics Sarcoma: Tips On days when you simply can't bring yourself to eat, don't worry.
Report a side effect to the MHRA. Postmenopausal women with early breast cancer scheduled to be treated with ARIMIDEX should have their bone status managed according to treatment guidelines already available for postmenopausal women at similar risk of fragility fracture.


text:
https://www.bso.org/Performance/Detail/79689 Symphony Hall Boston
301 Massachusetts Ave
Boston, MA 02115
Date Idea, Music
Tickets include a complimentary pre-concert reception at 7pm and patrons are invited to wear their favorite casual attire. Immediately after the performance, head to Higginson Hall in Symphony Hall's adjacent Cohen Wing for our complimentary post-concert reception with a cash bar and live band.
Associate Principal Trumpet Tom Siders will open the prgram with remarks from the stage.
French conductor Alain Altinoglu, making his BSO debut, leads this all-French program and is joined by his countryman, the violinist Renaud Capuçon, for Édouard Lalo's "Symphonie espagnole", written for the great Spanish virtuoso Sarasate in 1874 and a brilliant concerto in all but name. Berlioz's "Le Corsaire" Overture, by turns romantic and exuberant, opens the program. Albert Roussel's Suite No. 2 from his 1930 ballet "Bacchus et Ariane" was strongly championed with the BSO by Charles Munch.
The Conductor Cam seating allows patrons to watch the conductor from the orchestra's perspective. Screens will be placed in front of these sections.
Photo by Robert Torres.
The Casual Fridays Series is sponsored by Arbella Insurance Foundation.
#BSO1617 #BSOLalo #CasualFridays

domain: artistic


text:
The endemic Trochetia Boutoniana only found only on Le Morne mountain and was declared National Flower in 1992. The endemic Cassine Orientalis, or bois d’olive endemic to Mauritius can be found throughout the native forest of the country. The Diospyros tessellaria, or ebony tree, is endemic to Mauritius.
How Many Endemic Plants Are There In Mauritius
Mauritius Island is renowned for the extraordinary richness of its endemic flora, which is indicative of phytochemical diversity and is home to as many as 691 indigenous plant species of which 273 are single Island endemics.
Mauritius endemic plant species.
|Family||Plant species||Accession no||Site of collection|
|Asteraceae||Psiadia arguta Voigt(APA)||MAU 26407||Arboretum RobinsonCurepipe (National Park)|
|Psiadia lithospermifolia Cordem(APL)||MAU 26404|
|Psiadia viscosa (Lam.) A.J. Scott(APV)||MAU 26406|
|Ebenaceae||Diospyros boutoniana A.DC(EDB)||MAU 26412||Macchabee Forest(Black River Gorges National Park)|
|Diospyros nodosa Poir(EDN)||MAU 26411|
|Diospyros egrettarum I. Richardson(EDE)||MAU 26513||Curepipe|
|Diospyros leucomelas Poir(EDL)||MAU 26548||Black River Gorges National Park|
|Diospyros chrysophyllos Poir(EDC)||MAU 26547||Bel Ombre Forest|
|Diospyros pterocalyx Bojer ex A.DC(EDP)||MAU 26413||Le Pétrin(Black River Gorges National Park)|
|Erythroxylaceae||Erythroxylum hypericifolium Lam(EEH)||MAU 26548||Bel Ombre Forest|
|Erythroxylum laurifolium Lam(EEL)||MAU 25561||Cabinet-Magenta Black River|
|Sapotaceae||Mimusops balata (Aubl.) C.F.Gaertn(SMB)||MAU 26408||Arboretum Robinson Curepipe(National Park)|
|Sideroxylon cinereum Lam(SSC)||MAU 26409|
|Sideroxylon puberulum A.DC(SSP)||MAU 26410|
|Sideroxylon boutonianum A.DC(SSB)||MAU 23250||National park|
|Sideroxylon sessiliflorum (Poir.) Capuron ex Aubrév(SSS)||MAU 2,251||National park|
Read Also: How Many Tourists Visit Mauritius Each Year
What plants are endemic to Mauritius?
The endemic Trochetia Boutoniana is only found only on Le Morne mountain and was declared National Flower in 1992. The endemic Cassine Orientalis, or bois d’olive endemic to Mauritius can be found throughout the native forest of the country. The Diospyros tessellaria, or ebony tree, is endemic to Mauritius.
Which forests are endemic in Mauritius?
Endemic plants are found across a few forests in the south of the island but La Vallée des Couleurs Nature Park cherishes all its endemic trees and plants like the Ebenaceae or Black Ebony, Cassine orientalis or Bois d’Olive and the Bois de Natte among others and has dutifully protected the species.
Is Hibiscus endemic to Mauritius?
One of five Hibiscus species endemic to Mauritius, 𝑯𝒊𝒃𝒊𝒔𝒄𝒖𝒔 𝒇𝒓𝒂𝒈𝒊𝒍𝒊𝒔 is at risk of extinction due to hybridisation with the introduced Chinese hibiscus. This Critically Endangered species is one of 30 species that we are working on in collaboration with Fondation Franklinia and the Forestry Services to save.


text:
Title: [Analysis of head volatile constituents of Polyonum cuspidatum flower by HS-GC/MS].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20120201
Title: Self-organization of 1-methylnaphthalene on the surface of artificial snow grains: a combined experimental-computational approach.
Journal: The journal of physical chemistry. A 20111020
Title: Photochemistry of 2-diphenylmethoxyacetophenone. Direct detection of a long-lived enol from a Norrish Type II photoreaction.
Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20110901
Journal: Acta crystallographica. Section E, Structure reports online 20110601
Title: The reactivity of the 1,4-biradical formed by Norrish type reactions of aqueous valerophenone: a QM/MM-based FEP study.
Journal: The Journal of organic chemistry 20110204
Title: An extraction technique for analytical sample preparation in aqueous solution based on controlling dispersion of ionic surfactant assemblies in isotachophoretic migration.
Journal: Journal of chromatography. A 20110107
Title: Alkylresorcinol synthases expressed in Sorghum bicolor root hairs play an essential role in the biosynthesis of the allelopathic benzoquinone sorgoleone.
Journal: The Plant cell 20100301
Title: Solvent effects on photoreactivity of valerophenone: a combined QM and MM study.
Journal: The Journal of organic chemistry 20091204
Title: Characterization of an oligomeric carbonyl reductase of dog liver: its identity with peroxisomal tetrameric carbonyl reductase.
Journal: Biological & pharmaceutical bulletin 20070901
Title: Methyl chloroacetate as an extraction solvent for coupling liquid-liquid semimicroextraction with micellar electrokinetic chromatography through on-capillary decomposition for the separation of neutral compounds with concentration enhancement.
Journal: Journal of chromatography. A 20070413
Title: Inhibition of carbonyl reductase activity in pig heart by alkyl phenyl ketones.
Journal: Journal of enzyme inhibition and medicinal chemistry 20070201
Title: Synthesis of selective SRPK-1 inhibitors: novel tricyclic quinoxaline derivatives.
Journal: Bioorganic & medicinal chemistry letters 20050701
Title: Photodegradation of organic pollutants on the spruce needle wax surface under laboratory conditions.
Journal: Chemosphere 20041201
1016258-69-7 | 1-tert-Butyl 4-ethyl 4-(aminomethyl)piperidine-1,4-dicarboxylate | AA0004WX | MFCD14525454


text:
Have you ever wanted to grow your own flowers, vegetables and aromatic herbs, but never did because didn’t know where to start or had no time? There’s a solution now and it is called Click & Grow.
No special skills are required and you won’t have to worry about anything. This amazing pot uses artificial intelligence to grow herbs.
Click & Grow is an electronic SmartPot, i.e. an innovative pot that helps grow herbs without you doing anything. It’s your pot now to deal with watering and fertilizing.
SmartPot is equipped with electronic sensors, batteries, a pump, a water reservoir and a plant cartridge full of seeds, nutrients and a special software that helps grow and maintain herbs.
Should you need to change crops, you won’t have to buy another SmartPot. All you will have to do is simply replace the software and the seeds in the cartridge on the SmartPot you already have.
The only thing you will have to do is to fill the water tank and, from time to time, check that the batteries are charged. Then, you can just enjoy your plants growing and flourishing.

domain: agronomy


text:
Swinging Sixties Knitted Dresses
Two Original knitting patterns from the Sixties. A cocktail dress and a Short Strappy Evening dress.
1. AFTER SIX DRESS in 4 sizes.
AFTER SIX Four Sizes Bust 34-40” 10 to 13 balls.
Price 9d (old money)
This is a very elegant, sleeveless sheath dress with fabulous cut away armholes at the shoulder.
Condition of pattern is usable. It has a fold line down the front, slight tear at bottom of pattern where it folds in two, and 2 small biro notations on pattern instructions.
2. 'Chic' Evening Dress
TRICEL-NYLON GALAXIE (4 ply) to fit 32 to 36 bust
This is for a sparkly yarn mini dress pattern. It has narrow straps and a textured skirt.
Condition of pattern is quite good, without rips or marks.
Both garments are extremely attractive and wearable today.
UK p&p £1.10
USA p&p £4.42
G23 dresses - 100% in stock

domain: hobby


text:
Upperglade, WV Auto Insurance
If you are searching for the cheapest car insurance quotes in Upperglade, West Virginia, you have found the best website for that. CarInsuranceMinimizer.com can help you find the best suited car insurance solution for you. All you need to do is enter your Zip Code and start browsing through the best deals in West Virginia.
5 Tips for Cheap Car Insurance in Upperglade, WV
- Compare quotes from multiple providers. We highly recommend to use our simple search tool to locate the best car insurance options in Upperglade, WV. Simply enter your Zip Code and you are on your way to finding the cheapest vehicle insurance in the whole of Webster county.
- Know West Virginia car insurance laws. Vehicle insurance regulations differ from state to state. By knowing minimum car insurance requirements you can know what is the minimum legal coverage you can get away with. Learn more about West Virginia auto insurance requirements here.
- Your car make and model influences your premium. There can be big variation in premiums between different competing models. Check out our guides for the cheapest cars to insure in each class, but most importantly, if you are in process of looking for a new vehicle compare rates for multiple different car models.
- Make use of all available discounts. Ensure to qualify for as many discounts as you are eligible. Combining multiple car insurance discounts is a proven way to lower your premium by a huge percentage. Examples of most common auto insurance discounts offered in Upperglade, WV are multi-vehicle, multi-policy, military, student, clean driving record and many others.
- Raise your deductibles. If you are getting comprehensive or/and collision coverage as part of your insurance, you will be able to choose how high to set your deductibles. By setting your deductibles you will be able to lower your Upperglade car insurance premium. However, you will be effectively decreasing your coverage. To get even cheaper coverage, you can choose to select third-party liability car insurance coverage only. This is the cheapest option, but it is only available, if your vehicle is not being financed or leased.
Comparing car insurance quotes online is a proven way of finding cheap auto insurance in Upperglade. Use our simple search engine at the top of this page to find the best option for you! Get More Tips for Cheap Upperglade Vehicle Insurance
There are hundreds of diverse vehicle insurance organizations out there competing for your company, but most people do not consider the time needed to assess these companies and to locate out which insurance provider is giving the best package. Verify out these auto insurance policy tips to aid you make the appropriate insurance policies choice.Asking for an age low cost can help help save a bundle on car insurance for more mature drivers. If you have a clear driving report, insurance organizations are very likely to supply you greater charges as you age. Motorists among the ages of fifty five and 70 are most likely to be eligible for this sort of special discounts.When trying to save cash on your auto insurance policy, take into account possessing a anti-theft alarm or immobilizer set up on your vehicle. The likelihood of theft is a single of the main price factors in your insurance coverage premium, and an anti-theft unit decreases this risk. The reduce your danger, the lower your premiums turn into.Analysis the automobile insurance coverage organization prior to opening a plan with them. You will want to make sure that they are properly off. You do not want to get an insurance policies policy via a firm that is not undertaking nicely financially because you might be in an accident and they do not have the funds to go over you.Try to dig up as significantly details about how a certain car insurance policy organization handles statements. There are some out there that will get the perform completed on your automobile as quickly as your mechanic can do the function ,and there are others that will genuinely drag their feet when it will come to spending out a claim.If you can manage it, try to pay your car insurance coverage premium in complete. By paying out in entire, you might be able to steer clear of the desire costs that might be extra by having to pay with month-to-month payments. Some firms will also supply you with a low cost for paying your high quality in complete.Each year when your automotive insurance is up for renewal, store all around to verify that the premium becoming paid is even now marketplace competitive. There are an abundance of net facilities obtainable exactly where you can enter the automobile particulars on-line and immediately get insurance prices from various companies. This will confirm or deny that your recent top quality is realistic.It truly is all about obtaining the very best offer for the greatest cost when purchasing car insurance policy. Be positive that you might be not getting sucked into any insurance policies traps out there. Use the details you just realized in this post to assist guide you in your determination, and usually get the very best feasible plan.

domain: finance


text:
"Amidst the global sadness and suffering, I'm home," says TG4's continuity and weather presenter Mairéad Ní Chuaig. "I am fortunate to have spent most of the year in the beautiful wilds of Conamara."
The wrong of unshapely things
is a wrong too great to be told;
I hunger to build them anew
and sit on a green knoll apart,
With the earth and the sky and the water,
remade, like a casket of gold
For my dreams of your image that blossoms
a rose in the deeps of my heart.
We have all returned home. Cocooned from a threat that at times seems incredible yet all-encompassing. Amidst the global sadness and suffering, I'm home. I am fortunate to have spent most of the year in the beautiful wilds of Conamara.
I yearn for the sea and I swim daily at our local beach. It's life-affirming, as much wiser souls than I have noted. It's an opportunity to completely switch off from the never-ending cycle of breaking news. We have seen so many disruptions and disappointments this year, yet I find comfort in the ebb and flow of seasons.
I planted vegetables with my father in spring and enjoyed sharing the produce with our family and close friends. Chutneys and blackberry and apple jams are made and bottled. Perhaps the beginning of lockdown was not as challenging for me as it was for others. I have previously experienced the isolation that is required when receiving treatment for cancer. 'This too shall pass' is a phase that sustained me during my period of ill-health, and it sustains me now.
I've always felt incredibly lucky to work in the Gaeltacht. Although I miss the camaraderie and creative madness of my workmates in Baile na hAbhann, (TG4's studio base) I am happy that I can work creatively from home.
It is incredibly rewarding to see people take comfort in the service TG4 provides. Cúla4 ar Scoil is a wonderful resource for children and parents. TG4 also has a fantastic selection of box sets available on our Player. I'm heartbroken for the many artists, musicians and crews struggling in this climate.
Many of them are my dearest friends. I am also encouraged by theatres such as No Ropes Company, located in Galway, who continue to work on exciting future projects. I'm in awe of people who feel inspired during these troubling times.
Music is my life. Long walks with The Boss (Springsteen), Fleetwood Mac, Rory Gallagher, and Oasis are an essential part of my day. I switch off by re-watching sitcoms like Frasier, and at night escape into classic books I have always loved, novels like Wuthering Heights and Great Expectations.This year I've enjoyed Bailte on TG4, The Great British Bake Off, and Arracht, an incredible feature debut by Tom Sullivan. I love The John Creedon Show on Radio 1 and The Tom Dunne Show on Newstalk.
The unconditional love of pets is a balm for the soul. Rufus and Audrey and Tom, Ronnie and Pookie, our cats and dogs, and our ponies may never understand the joy they have given us during this period. Or maybe they do.
On reflection, amidst the saddening statistics we are faced with every day, I am grateful for my health and my family's health. My lasting memory of this year will be the warmth of friends and family supporting each other. Neighbours leaving apple pies at doors. Local fisherman bringing fish and crainneach (dillisk, a form of edible seaweed). The never-ending love of sisters and nieces, good friends who continue to make me laugh. I hope I've made them laugh a little too.
Is ar scáth a chéile a mhaireann na daoine.


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Dawn broke over the Sea of Cortez with a glimmer of sunlight, then cast its shimmer over the waters that lapped into the San José del Cabo Harbor. Tiny forms in the distance made themselves known as fisherman, boats and then buildings; mountains emerged in the far far distance, while the omnipresent palm trees took on form and detail nearby. Before the mist could disappear, the sun threw down a dreamy golden layer, ethereal and temporary, really just a brief promise of cool air, until the full-on sun would bring the day’s tropical still heat.♣
See more photographs from Mexico in my Mission Mexico series, where custom made prints start at $45. These dreamy scenes are from the Mexico Baja, made along the Sea of Cortez, in San José del Cabo (just beyond the better-known, but far more touristy, Cabo San Lucas).
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order robaxin online ratingWhatdistinguishes many of the experimental aspects of CT fromthose of traditional toxicology is the reliance on high-through-put order robaxin online in vitro methods.
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Piaget stated that the infant begins to form organized pat-terns of activity that are basic to the development of more complex cognitive functioning later(Phillips 1975, p.27). Rebound pulmonary hypertension is morelikely to be observed in infants exposed to higheriNO doses for several days and can usually beavoided by stepwise weaning to 1 ppm prior todiscontinuation Rebound pulmonary hypertension is morelikely to be observed in infants exposed to higheriNO doses for several days and can usually beavoided by stepwise weaning to 1 ppm prior todiscontinuation. Interestingly, studies of such patients undergoingneurosurgical operations have generally revealed positive results (Suess et al.
After the alignment and dissolution ofnuclearmembranes of the two pronuclei, the resulting zygote, withits diploid (2n) complement of46 chromosomes, undergoes amitotic division or first cleavage. Spacers can be obtained preformed and industrially loaded withantibiotics, or they can be produced custom-made with an individual antibiotic loadingwithout differences concerning infection control [89, 90]. 13.18 and Plate 35, page 440).Typically, the tunica intima ofa small artery has an internal elas-tic membrane, whereas this layer may or may not be present inthe arteriole. Schmidt and colleagues showed that a prototypebilateral TCD machine with a built-in algorithm to assess CPP and externally measuredvalues for arterial blood pressure has improved correlation with invasively measured per-fusion (48). The variability,or degree to which the scores spread out from the center of the distribution order robaxin online can be seengraphically by examining the width of the distribution. have described a similar analysis systemused in a series of 70 subjects (16). Magnetic resonance imaging (MRI) is considered to be thegold standard in local staging due to high soft-tissue contras.24 Recently order robaxin online it has beenshown that ultrasonography may have comparable accuracy with MRI, particularly inlocal staging of cervical cancer.25-27 The accuracy of ultrasonography is improved with theuse of power Doppler, which may help to detect abundant tumor vascularization anddynamic examination, enabling the differentiation of tumor or organ borders due to itsmovement aroused by the pressure of the probe inserted transvaginally, transrectally, or onthe abdominal wall. In infected hip and kneearthroplasties, DAIR should not be applied, if the soft tissue damage is moderate orsevere (e.g., abscess, sinus tract), and if there is a difficult-to-treat pathogen (e.g., rifampin-resistant staphylococci, fungi) [29, 48] (see Chapter 9). (2008)Ginkgo biloba for prevention of dementia: a randomized con-trolled trial (2008)Ginkgo biloba for prevention of dementia: a randomized con-trolled trial. Takata M order robaxin online Sasaki MS, Sonoda E, Morrison C, Hashimoto M, Utsumi H, Yamaguchi-Iwai Y,Shinohara A, Takeda S (1998) Homologous recombination and non-homologous end-joiningpathways of DNA double-strand break repair have overlapping roles in the maintenance ofchromosomal integrity in vertebrate cells.
This is a key factor for national health systems,which often struggle to meet the criteria of ef?ciency and cost-effectiveness ofpublic funds utilisation. The distal part of the lumen (away from thenucleus) contains a 20 kDa Ca2+-binding protein, centrin(Fig. In developingcredible risk assessments, it is important not only to considerthe cumulative impact of different chemicals affecting thesame target organ but also to recognize the potential for thesechemicals to interact. This will invariably require a refined understanding of MMM treatment thresholds,timeliness of intervention order robaxin online determination of effective treatments, and appreciation of thecomplementary value of various monitoring devices. However,certain lamivudine-resistant mutants becomeslow growing and have lower virulence. Noxious stimuli are much more difficult toaddress in a cat under anesthesia Noxious stimuli are much more difficult toaddress in a cat under anesthesia. The advantage ofallowing the patient to be awake does not alwaysapply in PICU, as often they will still requiresome sedation to tolerate being there attached toa ventilator and monitoring. Other chemokinereceptorsmay alsointeract with gp120proteins.
The epidermis, hair, nails, dental enamel, andhorny tissues are composed of keratin.) The epidermal layer isalmost completely replaced every 3 to 4 weeks. The neurosurgeon specializes in functional neurosurgery andthe two aneurysm surgeons are both away until Monday, but she decides to proceed.During the dissection around the aneurysm, an intraoperative rupture occurs and thesurgeon struggles for 20 min to obtain proximal control leading to intraoperativehypotension from blood loss and prolonged cerebral ischemia from temporary clip-ping The neurosurgeon specializes in functional neurosurgery andthe two aneurysm surgeons are both away until Monday, but she decides to proceed.During the dissection around the aneurysm, an intraoperative rupture occurs and thesurgeon struggles for 20 min to obtain proximal control leading to intraoperativehypotension from blood loss and prolonged cerebral ischemia from temporary clip-ping. Bar charts are a common and easy way to display such percentages.Figure 5.1 shows the results for current use of recreational (including illegal)drugs.
However, values of 0.85 or 1.30 are less intuitive; therisks are 0.85 or 1.30 times as large as that in the reference group. In adults, the sensitivity of the rapidstrep test is enough In adults, the sensitivity of the rapidstrep test is enough. There are a number of human diseases (discussedbelow) that result from small alterations in genes.
No malodorous,colored vaginal discharge on gloved ?ngers. The median/mean age of the adult patients has been reported to be around 29years  order robaxin online 37 years , and 50 years . High-frequency rates reduced the incidence of air leaksbut in studies conducted before the age of surfac-tant.


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In this commentary, we give a brief introduction and comment on the application prospect of pro/pre-B cell reprogrammed T cell which generated by the ectopic expression of hematopoietic stem cell-specific transcription factor Hoxb5 in mouse B cell in vivo. This de novo approach is potentially valuable for generating T cells for adoptive T cell immune therapy in future.
Keywords: Induced functional T cells, CAR-T, TCR-T, cancer immunotherapy, B cell reprogramming.
ACT: adoptive cellular therapy, CAR-T: chimeric antigen receptor expressing T cell, T-iPSC: T cell induced pluripotent stem cell, iHSC: induced hematopoietic stem cells, TCR: T cell receptor, ETPs: early T cell lineage progenitor-like cells, DLL1/4: notch receptor ligand Delta-like 1/4.
The fate of hematopoietic cell can be modified or totally overset by genetic engineering technique. Attempts to convert B into T cells by silencing ‘master genes’ of the B cell lineage have had limited success (Cobaleda et al., 2007; Ungerback et al., 2015). Recently, a report showed that expression of hematopoietic stem cell-specific transcription factor Homeobox B5 (Hoxb5) in mouse B cell progenitors successfully reprogramed those cells into functional T cells in vivo. This de novo approach is potentially capable to generate T cells for adoptive T cell therapy (ACT) in future. Here we summarized a brief commentary on the application prospect of this induced functional T cells (iT) generation strategy by this reprogramming approach.
Chimeric antigen receptor -T cells (CAR-T) and T cell receptor-T cells (TCR-T) are promising forms of immunotherapy against leukemia and solid tumors (Im and Pavletic, 2017; Lin et al., 2017; Kasakovski et al., 2018). However, conventional CAR-T and TCR-T cell products are mainly derived from the autologous peripheral blood of patients, whose T cells occasionally showed functional exhaustion, senescence, and reduced response to activation, which were correlated with patient’s age, tumor burden or microenvironment (Crespo et al., 2013; Vicente et al., 2016; Lin et al., 2017; Kasakovski et al., 2018).
In order to overcome difficulties faced in CAR-T and TCR-T production, which were caused by the limited quantity, function impairment and the terminal differentiated state of autologous T cells from patients, an alternative approach has been attempted in the T cell regenerative filed by generating tumor targeted T cells from induced pluripotent stem cells (iPSCs), which are reprogrammed from somatic cells, such as peripheral blood cells and even T cells (Loh et al., 2010; Themeli et al., 2013; Vizcardo et al., 2013).
Published studies have shown that pro-B cells are highly plastic for reprogramming (Xie et al., 2004; Cobaleda et al., 2007), and these cells have been successfully converted into T cells by dedifferentiation to uncommitted blood progenitors (Cobaleda et al., 2007; Ungerback et al., 2015). Recently, Wang and colleagues reported that iT cells can be generated by the expression of HSC-specific transcription factor Hoxb5 in pro-pre-B cells in vivo.
Surprisingly, Hoxb5 directly reprogrammed B cells into early T cell lineage progenitor-like cells (ETPs) by a trans-differentiation process, since no donor-derived uncommitted hematopoietic progenitor cells were detected in the recipient mice. The induced ETPs in bone marrow can further complete mature T cell development in the thymus microenvironment and finally express polyclonal TCR β chains. The mature T cell derivatives were capable of secreting IL-2, IL-10, IFN-γ and TNF cytokines in response to monoclonal anti-CD3 and anti-CD28 antibody stimulation, and capable of proliferating after allogenic cell-stimulation in vitro.
Furthermore, in vivo study identified that these iT cells rejected allogenic skin graft and formed adaptive immunological memories (Zhang et al., 2018). Despite the efficiency of lineage conversion is currently low (1%), pro/pre-B cells expressing retro-Hoxb5 failing to generate ETPs were still able to differentiate normally into B cells, which reduces the risk of generating unknown pluripotency cells with tumor potential. It has been considered as a potential risk of iT cells by reprogramming and induction approaches (Loh et al., 2010; Vizcardo et al., 2013).
In addition, the shorter lifespan of those iT cells also decreased the tumorgenesis risk compared with those less differentiated cell types. Thus CD8+ iT cells generated by this single transcription factor reprogramming might be potentially applied to treat lymphocytopenia related autoimmune deficiency diseases. Particularly, when combined with anti-tumor specific TCR gene or CAR-T gene transfer, they could be one possible source of T cell generation for treating metastatic cancer and virus-infection, especially for who do not have enough natural tumor- or virus-specific T cells for ACT.
Undoubtedly, this de novo type of CD8+ iT cells is a budding star for cancer immunotherapy. Several challenges remain to be addressed before clinical application of the reprogrammed T cells into immunotherapy. For example, when they are applied in TCR-T production, methods for endogenous TCR gene silence or modification on the transferred TCR gene should be considered to avoid the mispairing of transferred and endogenous TCR chains, which may resulting in unspecific reactivity (Cobaleda et al., 2007).
In addition, reprogramming efficiency needs further improvement to meet the requirement of bulk cell numbers for ACT. For the purpose of more convenient and fast generation of T cells for clinical usage, it is necessary to indicate that whether HOXB5 expressing human B cells can be successfully converted into T cells in the humanized mice model transplanted with human thymus, fetal liver and HSCs (BLT mice).
Alternatively, an ex vivo iT cells induction system whether can be established in the presence of stromal cells expressing notch receptor ligand Delta-like 1 (Dll1) or Dll4. If these issues could be solved, the ACT approach using autologous ihCD8+T cells from lineage-conversion will worth an attempt. Promising methods to generate reprogrammed T cells for ACT including the new reprograming method.
Generating fully functional T cells in vivo by ectopic expression of HSCs transcription factor Hoxb5 in pro-pre-B cells hold great promising for treating patients who suffer with T cell immune deficiency diseases in the future. Combined with CAR and tumor antigen specific TCR gene transfer techniques, they are also promising in cancer immunotherapy, however, a lot of challenges are still facing before arrive at the real clinical transformation.


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Whole Foods Market has leased the Mill Valley site of a former Albertsons store at 731 E. Blithedale Ave., dashing hopes of some that the space would be taken over by Trader Joe's.
The Texas-based grocery chain has a popular outlet no more than two miles away at 414 Miller Ave., but Whole Foods officials say there are no plans to close it.
Cynthia Leo, manager of the Miller Avenue store, said the new store is expected to open in spring 2008. She said she was unable to provide additional information.
Kathy Severinson, executive director of the Mill Valley Chamber of Commerce, who talked with Whole Foods officials, said the Miller Avenue store will be remodeled.
She said Whole Foods wanted another site nearby because the Miller Avenue site is smaller than most of its stores and another could provide a variety of services, such as an expanded delicatessen, not available at the present site.
Severinson dismissed as unwarranted rumors that Whole Foods leased the new space to keep Trader Joe's out of Mill Valley.
Still, city officials have made no secret that they thought Trader Joe's was a perfect fit.
There had been hope in the community that the remodeled Strawberry shopping center would entice Trader Joe's to open a store at a space later claimed by the upscale garden store, Smith & Hawken.
The East Blithedale site is owned by Albertsons, and Tom Gates, a Realtor with Albertsons' real estate arm in Chicago, said Mill Valley City Manager Anne Montgomery asked him to get Trader Joe's to lease the space.
Mayor Christopher Raker stressed on Thursday that the city could make no regulatory move to attract Trader Joe's because the use permit that would be transferred from Albertsons to another tenant was out of the purview of the city.
The city could only become involved if there were to be new construction or something that would affect parking, in which case a new permit would be required.
Read more Mill Valley stories at the IJ's Mill Valley page.
Contact Don Speich via e-mail at firstname.lastname@example.org

domain: economics


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My mom died when I was 19. She fought a 10-year battle with breast cancer, refusing treatment, dying at home. The details are too awful to describe.
These are the things she never knew about me:
• I graduated from UC Berkeley
• I have a Master’s Degree from UCLA
• I have two amazing kids
• I married a wonderful guy
• I miss her every day. Every single day.
There was a lot she did know about me:
• I loved her and still do. Always will.
• I didn’t want her to die. I begged her not to die
• I’d make it without her. Somehow.
• I’d never forget her
I’m crying as I write this. My mom was my most important influence, my mentor and my biggest supporter.
After she died, my soul was broken. With determination and an aching heart, I kept going, one foot in front of the other, with the support of my dad and sister.
Today, I’m a mom whose greatest fear is that something will happen to me and I won’t be there for my kids. This is the legacy of losing my mom as a teenager. It’s not an abstract notion. It’s the reality I live with daily.
I honor my mom’s memory is ways that surprise me. I grew up in Topanga, CA, a stunning, rustic canyon outside of Los Angeles. A few days ago, my family moved to Coldwater Canyon, the hills above Los Angeles. I want to give my kids everything my mom gave me.
The most profound and moving example of a mother’s love I’ve ever heard is represented by a 2010 interview on National Public Radio, where Lonnie G. Bunch, director of the Smithsonian’s project to collect artifacts for the National Museum of African American Art And Culture, discusses unique items the public donates to the museum.
“Somebody brought a pillowcase that was embroidered. And it turned out to be a pillowcase that was embroidered by a woman who was enslaved, who was about to be sold the next day. So, she embroidered to her daughter saying, in this pillowcase you will find a dress, you will find some biscuits but what you’ll find is that it’s filled with my love. And though I may never see you again, always know how close you are to my heart.”
My mom, a strong African American woman, didn’t leave me with a real pillowcase filled with treasures. Instead, she left me with a metaphorical one filled with the life skills, the determination and the fortitude to make it in this world without her.
Christina Simon is the co-author of “Beyond The Brochure: An Insider’s Guide To Private Elementary Schools In Los Angeles.” She also writes the blog, www.beyondthebrochure.blogspot.com about applying to private elementary schools in Los Angeles and the ups and downs as life as a private school mom. Christina’s blog was just voted “Top 25 Parent Resources” by Circle Of Moms. She has written recent guest blog pieces for The Culture Mom, BlogHer Syndication, Mamapedia, The Mother Company, The Well Mom, Sane Moms, Eco Mom, Macaroni Kids, A Child Grows In Brooklyn, Power Of Moms, The Twin Coach and Diaries Of A Mixed (Up) Kid. Christina is a former vice president at Fleishman-Hillard, a global public relations firm. She has a 7-year-old son and a 10-year-old daughter. Christina lives in Los Angeles with her husband and kids.


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NOTTINGHAM, England — The University of Nottingham is developing a solar air conditioning system that is said to have the capability to cut electricity consumption by up to 50 percent compared to conventional vapor compression (VC) systems.
Dr. Jie Zhu, from the Department of Architecture and Built Environment at The University of Nottingham, and Professor Tingxian Li, Shanghai Jiaotong University, China, are conducting this research supported by the Royal Society.
The two institutions are investigating a new air conditioning technology, powered by solar energy, whose features include:
• The ability to condition the air and control humidity independently.
• A sorption thermal battery that combines heat and cold energy storage in one unit and has the ability to achieve thermal energy storage with controllable temperature.
Zhu said, “A VC cooling system adopts a condensation dehumidification method to handle both sensible and latent heat loads. This means the system has to operate under lower evaporation temperatures, which results in lower cooling capacity, lower coefficient of performance (COP), and sometimes a reheating process is required to meet supply air requirements.
“We are proposing a temperature and humidity independent control technology to solve this problem. This system can save 25-50 percent electrical consumption and COP increases about 40-60 percent, thus greatly reducing operating costs, compared to the conventional VC system.”
Thermal energy battery storage plays a key role in the use of solar energy for heating and cooling due to solar’s inherent fluctuation and the lack of year-round sun in many countries.
The solid-gas sorption thermal battery has the capability to store both heat and cold energy at a controllable temperature in a single unit. The heat energy is used to power the dehumidification subsystem, while the cold energy is used to cool the air circulating in the indoor environment.
The proposed system consists of heat-powered membrane liquid-drying dehumidification and solar sorption thermal battery units. Two sorption thermal battery units are used to ensure the system continuously operates.
To remove moisture and latent heat from the incoming supply air stream, the air conditioning system uses a liquid desiccant material which attracts and holds water vapor. During the regeneration process in the dehumidification unit, the desiccant solution is heated by the sorption heat of the battery and then flows into the regeneration cabin where the warmed desiccant solution will remove moisture from the air.
Afterwards, as the air reaches a water-air cooler, it is cooled by chilled water produced by the evaporation heat of refrigerant from the sorption thermal battery. This cyclical process ultimately generates the dry and cooled supply air which is released into a space.
The proposed research is investigating new composite sorbents, thermal energy storage capacity, heat and mass transfer properties, and will assess economic and environmental impacts using theoretical and experimental measures.
A small scale prototype system will be designed, constructed, and tested to evaluate the proposed system performance on cooling, dehumidification, and energy storage.
“Solar air conditioning is one of the promising technologies to alleviate the huge demand for energy resources. It has the potential to provide a viable alternative to conventional air conditioning systems,” said Zhu.
More information is available from Dr. Zhu at firstname.lastname@example.org.
Publication date: 9/13/2016
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Calibration pressure: 1.8 bar, steam release: 6.3 Kg/h.