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“Processing Room,” Hanford History Project, accessed June 8, 2023, http://hanfordhistory.com/items/show/4775.

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Lafayette city development plans tackle projected population increase
More than 25 people attended a presentation Thursday at the Rosa Parks Transportation Center, where redevelopment plans for three small areas across Lafayette Parish were revealed.
Kevin Blanchard, chief development officer for Lafayette Consolidated Government, said the three areas — near Bertrand Drive, the Northgate Mall and Milton Avenue — are where the Lafayette Consolidated Government wants to encourage the projected 90,000 people who are moving here within the next 20 years to live.
The redevelopment is part of the Lafayette Comprehensive Plan, and it is not without challenges. Thirty-seven percent of the areas, Blanchard said, fall within severe flood-zone sites, which poses a costly problem.
“The path we are headed down is an expensive one, for both the private sector and the government,” he said.
Blanchard said instead of expanding, “we should turn around to look at the parts of our city that are ready for redevelopment.”
City planner Cathie Gilbert said the three small areas represent different but unique aspects of the parish.
“We wanted a suburban (Northgate), urban (Bertrand) and rural (Milton) example to show how part of the comprehensive plan could be implemented in the south of the parish, in the north of the parish and in the center of the city,” she said.
With the Lafayette Central Park in the works at the Horse Farm and some construction for the UL athletics facilities master plan under way, Blanchard said it is the consolidated government’s job to “provide that missing link,” which is Bertrand Drive. He said the four-lane road does not need to be so wide, and two of its lanes could be transformed for safe walking and biking lanes.
Blanchard said an ideal Saturday would be a family attending the farmers market at the Horse Farm in the morning and then walking across Bertrand to get lunch on the way to a UL athletic event — all without getting a car to further clog already congested traffic.
Gilbert said the public will “take over the street for a day” on May 31, reducing Bertrand to two lanes and enhancing it with “fake street trees and cafe chairs” to promote a more urban environment. The plan is a Better Block project, a nationwide movement. Its website says it gets “communities together to revitalize a single commercial block in an underused neighborhood corridor.”
“It’s a way for people to see that the street is not just a place for cars,” Gilbert said. “It can also be a place for people to interact.”
The city-parish government estimates the Bertrand Drive area will grow by 2,000 housing units and 1,200 jobs over the next 20 years.
A problem to address near Northgate — deemed the North Gateway — is providing easy and safe ways to cross Evangeline Thruway, which splits that area. Gilbert said North Gateway was chosen partly because of the projected I-49 connector, although the elevated 5.5-mile, six-lane highway is still only in the planning phase. This area is expected to grow by 2,100 housing units and to add 1,100 jobs in the same 20-year period.
Although Gilbert said she has heard only traffic concerns in Milton, namely near the elementary school, Blanchard said “it would be great” for the unincorporated town to receive sidewalks.
“Someone told me, ‘But, Kevin, no one walks in Milton,’” Blanchard said. “Of course, they don’t! They don’t have sidewalks.”
Milton is projected to grow by 900 housing units and 990 jobs in the next two decades.
For the next two weeks, these drafts will be posted online, allowing more time for residents to voice opinions about the plans. Gilbert said the link will soon be posted on planlafayette.org.
“This process is where we’re going as a community and how we’re going to get there,” Blanchard said, adding that the plans will be attached to the overall comprehensive plan, which he said he hopes will be adopted by the Planning Commission in June.
“The potential is here,” Gilbert said, “but now we just have to prioritize how to better spend our money.”


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Clinical flow cytometric screening of SAP and XIAP expression accurately identifies patients with SH2D1A and XIAP/BIRC4 mutations
Version of Record online: 19 FEB 2014
© 2014 Clinical Cytometry Society
Cytometry Part B: Clinical Cytometry
Volume 86, Issue 4, pages 263–271, July 2014
How to Cite
How to cite this article: Clinical Flow Cytometric Screening of SAP and XIAP Expression Accurately Identifies Patients with SH2D1A and XIAP/BIRC4 Mutations. Cytometry Part B 2014;86B:263–271., , , , , , ,
- Issue online: 13 JUN 2014
- Version of Record online: 19 FEB 2014
- Manuscript Accepted: 3 FEB 2014
- Manuscript Revised: 11 NOV 2013
- Manuscript Received: 10 JUN 2013
- X-linked lymphoproliferative disease;
Introduction: X-linked lymphoproliferative disease is caused by mutations in two genes, SH2D1A and XIAP/BIRC4. Flow cytometric methods have been developed to detect the gene products, SAP and XIAP. However, there is no literature describing the accuracy of flow cytometric screening performed in a clinical lab setting.
Methods: We reviewed the clinical flow cytometric testing results for 656 SAP and 586 XIAP samples tested during a 3-year period. Genetic testing was clinically performed as directed by the managing physician in 137 SAP (21%) and 115 XIAP (20%) samples. We included these samples for analyses of flow cytometric test accuracy.
Results: SH2D1A mutations were detected in 15/137 samples. SAP expression was low in 13/15 (sensitivity 87%, CI 61–97%). Of the 122 samples with normal sequencing, SAP was normal in 109 (specificity 89%, CI 82–94%). The positive predictive values (PPVs) and the negative predictive values (NPVs) were 50% and 98%, respectively. XIAP/BIRC4 mutations were detected in 19/115 samples. XIAP expression was low in 18/19 (sensitivity 95%, CI 73–100%). Of the 96 samples with normal sequencing, 59 had normal XIAP expression (specificity 61%, CI 51–71%). The PPVs and NPVs were 33% and 98%, respectively. Receiver-operating characteristic analysis was able to improve the specificity to 75%.
Conclusion: Clinical flow cytometric screening tests for SAP and XIAP deficiencies offer good sensitivity and specificity for detecting genetic mutations, and are characterized by high NPVs. We recommend these tests for patients suspected of having X-linked lymphoproliferative disease type 1 (XLP1) or XLP2. © 2014 International Clinical Cytometry Society

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which social enterprise and impact investment can flourish, GSEN is the global network of organisations supporting early stage social entrepreneurs. Our vision is that social entrepreneurs can access great support, no matter where they live. Every year, GSEN members support thousands of social entrepreneurs across the 6 continents to create sustainable social change benefitting millions …... Figure 1: Social enterprise stages of growth and lessons learned from ISEF pilot1 The ISEF pilot confirms that the concessional loan and grant product is an attractive offering to ISEs seeking operational scale and achieve self-sustainability.
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Genesco Inc. today reported third-quarter sales and profits that topped analysts’ expectations, thanks to a strong performance by teen mall staple Journeys as well as solid advances at its Johnston & Murphy division.
The former saw comparable store sales rise 9 percent, and the latter enjoyed a gain of 10 percent during the period — boosting the firm’s adjusted earnings to 95 cents per share. Analysts had expected Genesco to post earnings of 86 cents per share. (The company also reversed last year’s net losses to post profits of $12 million, or 74 cents per diluted share.)
Overall, Genesco’s sales dipped 1 percent to $713 million, reflecting a calendar shift as opposed to lagging momentum, according to president, chairman and CEO Roger Dennis. Despite the moderate declines, those results topped analysts’ forecasts for $712 million. The firm’s comparable sales also improved 4 percent — the highest quarterly comparable sales increase at the company in more than two years, driven by “the ongoing strength of our U.S. footwear businesses,” Dennis said.
“Journeys and Johnston & Murphy delivered strong performances both in-store and online, which fueled an acceleration in our combined consolidated store and digital comps on a sequential basis,” he added. “While still negative, sales trends at both the Lids Sports Group and Schuh Group continued to improve following a very challenging start to the year.”
Comparable sales at Lids fell 2 percent during the period, an improvement from last year’s same period, when comps fell 6 percent. But, Schuh’s comps’ dipped 4 percent, compared with a gain of 4 percent last year.
Looking ahead, the company narrowed its previously announced guidance range for adjusted earnings per share and reiterated its expectation that earnings for the year will be near the midpoint of the range. Genesco expects comparable sales to be up 2 percent to 3 percent and adjusted diluted EPS in the range of $3.10 to $3.40.
Despite a better-than-expected performance during the period, investors sold off Genesco’s shares sending the stock down 1.5 percent to $42.36 as of 11:30 a.m. ET. (Overall, the markets have been down for much of the morning on fears over U.S.-China relations and tumbling crude oil prices.)
Journeys Is Selling a Lot of Shoes — Now Genesco Is Back in the Black

domain: news


One of many new initiatives launched by Beverly Hills Mayor Lili Bosse came to fruition on April 25, where hundreds of people came out for the first Business with Bosse event held at Tommy’s Beverly Hills. Roughly 250 community members, from school board members to city commissioners and nearby business owners, gathered with the mayor over complimentary sliders at the restaurant’s outdoor patio and lounge. The Business with Bosse program is designed to spotlight and celebrate different Beverly Hills businesses, showcase city offerings, stimulate the local economy and foster a sense of community. Every few weeks, Mayor Bosse will visit a different establishment, inviting the public to join her.
“For me, this actually exceeded my wildest dreams,” Bosse told the Courier. “It’s the first time after two very challenging years, that we as a community can finally come together again. We can smile together again, touch one another together and just celebrate each other and celebrate what we love the most about our community, which is that it feels like an extended family. Tonight felt that way. Tonight felt like coming home again.”
The relatively new eatery opened on Feb. 15 at 235 N. Canon Drive, occupying the two-story old Bouchon space at Beverly Canon Gardens, which closed in 2017. The restaurant comes from Tommy Salvatore, formerly the manager at Craig’s in West Hollywood, and the kitchen is helmed by Executive Chef Vartan Abgaryan. According to Salvatore, Tommy’s was “thrilled” to be the first participating business.
“This is another outstanding event that Mayor Bosse is doing to bring the community together,” Beverly Hills Fire Department Chief Greg Barton told the Courier. “It really shows off what the city has, what the restaurants are, and what’s available.”
“It was a wonderful community event,” Arts and Culture Commissioner Karla Gordy Bristol told the Courier.
“Just being able to look around and see faces that I used to see and meet new residents that have moved here over the last two years, and this is their first face-to-face experience with Beverly Hills,” Bosse told the Courier. “It’s a way to really showcase our incredible businesses and for the businesses to really experience what the Beverly Hills way is, which is an extended family. It’s welcoming, it’s loving, and you just felt this vibrancy and electricity tonight. So, the best is yet to come because this is the first, and it just feels magnetic.”
The next Business with Bossee events will be held on May 19 from 9 to 10:30 a.m. at Chaumont Bakery and on May 23 from noon to 1:30 p.m. at Alfred Coffee Beverly Hills. Special offering details are expected to be announced soon.


Understanding what each of these terms mean can help when it comes to understanding the industry jargon associated with insulation, energy issues and climatic zones.
This quick guide to some commonly used terms - and what they actually mean:
U-value is an international rating system used by the glass and glazing industry. U-value measures the rate of heat transfer through glass (glazing). This means that products with a lower U-value will have better insulation properties and therefore be more energy efficient. U-values depend on climatic conditions.
R-value measures a building product’s resistance to heat flow - i.e. how well it insulates but is more often used in the construction and building industry to measure insulation of walls and ceilings. The higher the R-value, the better the insulation and the greater the improvement to your home or building's energy efficiency. This correlates with greater energy savings.
Knowing what R-value and U-values mean is important when considering insulating your home for energy efficiency. These values also assist when selecting products that best suit your home or building’s climate zone.
SHGC stands for Solar Heat Gain Co-efficient. SHGC refers to the total amount of solar energy that enters a building through glass/glazing. In other words, how well the windows block out the heat caused by sunlight. SHGC measures both direct solar radiation as well as that which is absorbed and released inward. SHGC is calculated as a number between 0 and 1. The lower the SHGC of the windows, the less heat gains into the home.
SHGC can have an effect on the amount of visible light that is transmitted: the lower the SHGC, the lower the level of visible light which can affect the brightness of a room’s interior.
UV transmission refers to the amount of ultra violet light from the sun that is transmitted through glass windows. Besides its harmful effect on human skin, ultra violet light can also damage furniture, carpets and other household items. UV transmission is most often measured in the 300 – 400nm wavelength range.
VLR stands for Visible Light External Reflectance. This refers to the percentage of visible light that is reflected externally by a glass as detected by the human eye. This is a useful measure for glass where restrictions exist on the level of reflection allowed. The higher the percentage number the greater the mirror-like appearance.
VLRi stands for Visible Light Internal Reflectance and refers to the percentage of visible light that is reflected internally by a glass as detected by the human eye. This is a useful measure when determining the level of internal reflectance at night time. All glass products (apart from specialty anti-reflecting products) have internal reflectances which make it difficult to see clearly out of a window at night time with lights on inside. Internal reflectances increase with the use of reflective coated glass products.
RW stands for the Weighted Sound Reduction Index and measures the reduction of sound decibels transferred through a single building element. The higher the RW rating, the better the sound insulation.
STC stands for Sound Transmission Class. The STC reflects the amount of noise that is reduced when sound passes through a window.


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2761 East Hwy 169
Grand Rapids, MN 55744
Used 2015 Forest River RV Salem Villa Series 426-2B Classic
The Salem Villa 426-2B Classic destination trailer by Forest River features triple slides, three entrance doors, and two full bathrooms!
Stepping inside the trailer, to the left there is a double kitchen sink, three burner range, microwave, refrigerator, and pantry. The opposite side has a slide with a u-shaped dinette and a sofa. Next to the slide you will find a nice size entertainment center.
As you proceed toward the front of the trailer there is a side aisle bathroom on the left. Inside the bathroom you will find a sink, medicine cabinet, neo-angle shower, wardrobe with drawers and a toilet.
You can enter into the front bedroom from either the hallway or from the private entrance from the bathroom. In the front bedroom there is a slide with a queen bed and nightstands on either side of the bed. Along the front wall of the room you will find so much storage with the wardrobe. Across from the bed there is a dresser with an overhead cabinet. Also in the front room there is a private entrance door which leads outside.
The rear bunk house has a slide with a set of bunks, or an optional jiffy sofa in place of the lower bunk. Across from the bunks there is an entertainment center and wardrobe.
Off of the bunk house you will find a bathroom with a shower, toilet, linen cabinet, sink, and medicine cabinet. There is also a private entrance door from the bathroom leading outside.
|Length||40 ft 5 in|
|Ext Width||8 ft|
|Ext Height||12 ft 3 in|
|Int Height||7 ft|
|Hitch Weight||1365 lbs|
|Dry Weight||10175 lbs|
|Cargo Weight||1290 lbs|
|Fresh Water Capacity||39 gals|
|Grey Water Capacity||80 gals|
|Black Water Capacity||62 gals|
|Furnace BTU||35000 btu|
In 1996, Forest River founder Peter Liegl had a vision. He foresaw an RV company dedicated to helping people experience the joy of the outdoors by building better recreational vehicles. Today, we have grown to become one of the largest RV manufacturers in North America, producing class A and C motorhomes, travel trailers, fifth wheels, toy haulers, camping trailers and destination trailers. From the new family just starting out in the world of RVing to the experienced full-timer, we offer something for everyone.
Forest River RV is a division of Forest River, Inc., a Berkshire Hathaway company, which produces recreational vehicles, pontoons, park models, buses, cargo trailers and commercial trucks. The diversity of Forest River, Inc., enables us to approach the RV industry with a unique perspective, incorporating lessons learned at each one of our divisions. Operating with openness across a wide range of products is what makes us stand apart from the competition. At Forest River, Inc., quality and dependability are a necessity in everything we make.


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BackgroundThe N-terminal fragment of pro Brain Natriuretic Peptide (NT-pro BNP) is a neuro-hormone synthesized in the cardiac ventricles in response to increased wall tension. The purpose of this study was to assess the correlation between the NT-pro BNP levels and the New York Heart Association function class (NYHA Fc) of dyspnea and echocardiographic findings for the patients who visited our cardiology departments.MethodsFrom October, 2002 to April, 2003, serum NT-pro BNP levels were measured in 348 patients who visited the Samsung Medical Center and the Jong Koo Lee Heart Clinic.ResultsThe NT-pro BNP levels were increased with the progression of NYHA Fc of dyspnea (p<0.001 by ANOVA), the increase in the systolic left ventricular internal dimension (p<0.05), and the decrease in the ejection fraction (p<0.01). For the NYHA Fc I patients, the NT-pro BNP levels were positively correlated with age (p<0.001) and left atrial size (p<0.001). For the patients with ischemic heart disease, the NT-pro BNP levels were also positively correlated with the NYHA Fc (p<0.001 by ANOVA). The NT-pro BNP levels were increased with the increase in the systolic (p<0.001) and diastolic pressure (p=0.017), the left ventricular internal dimension as well as the decrease in the ejection fraction (p<0.001). The area under the receiver operating characteristic (ROC) curve for the NT-pro BNP levels was 0.994 (95% confidence interval, 0.979-0.999), and the most reliable cut-off level for the NT-pro BNP was 293.6 pg/mL.ConclusionThe NT-pro BNP levels were positively correlated with the NYHA Fc of dyspnea and the systolic dysfunction for the patients who visited our cardiology departments. A 300 pg/mL value for the NT-pro BNP cut-off point appears to be a sensitive level to differentiate dyspnea originating from an ailing heart or not for the patients who visited our cardiology departments.
DOI 인용 스타일

domain: literature


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This season's new look of small in size but huge in impact bags with a jelly texture. A quality and high-end finish with a stylish silhouette.
- Whimsical in a translucent jelly vinyl texture of a romantic magenta purple & seafoam green colors
- 8 ½” x 2 ¾” x 3”
- Quality gold tone snap clasp closure
- Detachable matching pink strap for versatile cross body convenience
- Additional Information

domain: design


Ailing Asian black bear captured in Thailand
BANGKOK — An ailing Asian black bear was captured for rehabilitation in Prachin Buri’s Prachantakham district on Wednesday night after it came out of a forest to search for food.
Officials of the forest reserve management zone 1 of Prachin Buri rushed to Moo 13 village in Tambon Pho Ngam after a local villager spotted the black bear in his banana plantation.
The villager, Boonchuay Simprasert, 60, said he tried to scare the bear to return to a nearby mountain but it would not leave his plantation and it appeared to stagger while walking.
Officials used a tranquilizer dart to put the bear to sleep before it was carried out of the plantation in an iron cage.
The male bear is about three to four years old but it weighs just 60 kilograms because it is apparently sick.
The bear will be sent to the Nakhon Nayok wildlife rehabilitation centre and released later.
Subscribe to INQUIRER PLUS to get access to The Philippine Daily Inquirer & other 70+ titles, share up to 5 gadgets, listen to the news, download as early as 4am & share articles on social media. Call 896 6000.


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Our CEO on Foreign Employees in CZ
Our CEO Andrea Tkačuková has been quoted in a recent ABSL article on the continual effort of Czech companies to keep employing foreigners in spite of the ongoing crisis.
Despite the current crisis, the Czech market is still actively recruiting, even qualified candidates from abroad. And it takes a minute for them to get used to Czechia and overcome some of the baffling obstacles here.
For example, as our CEO Andrea Tkačuková says in this ABSL Czech Republic article, although expats find it unsettling that they have to often spend more than half of their income on accommodation, they don't at first realise that the cost of services is generally cheaper here so they will be able to live here in comfort nevertheless. Read more below.
Do you need help? email@example.com +420 211 221 492 Fill our form


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Bentley Mulliner Bacalar
A car that will blow the roof off – yes, it literally has no roof. Reaching a top speed of 200 mph and priced at a cool $2 million, only 12 will be made … and they’re already sold out.
The British carmaker named the car after Laguna Bacalar in Mexico, and if you look closely, the lake’s blue hue is reflected on the car’s digital dial display.
While the open-top two-seater shares the Continental GTC frame and door handles, the ultra-exclusive speedster boasts all new exterior body panels and borrows futuristic features inspired by their award-winning EXP 100 GT electric concept car.
A car this exclusive needs some of the bespoke and hand-built details Bentley is famous for. The dashboard is made from a preserved wood from trees that died millennia ago, while each seat has a quilted pattern that requires close to 150,000 stitches (totaling 400,000 individual stitches in the interior). Cabin details can be completely specified by each customer, working hand-in-hand with Mulliner.
Throughout the grand tourer, materials are ethically sourced using sustainable craftsmanship. For example, the exterior’s paint glistens with silicon dioxide that is obtained from rice husk ash.
Mechanically speaking, it is powered by a 6.0-liter W12 turbocharged engine and is estimated to have a 3.5-second 0-to-60 time while delivering 650 horsepower and 667 lb-ft of torque.
This year’s most highly anticipated SUV is no doubt the new Escalade, which has a debut scheduled for later in 2020. Will it live up to the hype? Well, the flagship of the Cadillac brand does come equipped with a lot of firsts – to say the least.
Let’s jump right into that. The fifth-generation SUV comes in five trims and two design themes, including the first-time Sport, which includes black accents. For smooth driving, the first true hands-free driver-assist feature for compatible highways called Super Cruise will probably come in handy. It offers new enhancements such as lane change on demand functionality and overhead view cameras.
On the entertainment side, the industry’s first curved three-in-one OLED touchscreen offers augmented reality, Apple Play/Android Auto and more.
That covers vision and accessibility; now we need sound to match. Exclusive to Cadillac, the massive SUV comes standard with a new 19-speaker (optional 36-speaker) AKG surround-sound audio system – they’re found in the doors, headliner, instrument panel, center console, head restraints and in the airbag compartments. If you’re looking to stretch your legs a little more, the long-body ESV option adds 15.9 inches in length while keeping all the same features.
We can’t forget about the drive. The 6.2-liter V8 engine cranks out 420 horsepower and 460 lb-ft of torque. It makes a sprint from 0 to 60 in 5.5 seconds.
The new Escalade can be yours starting at $76,195.
Chevrolet Corvette C8
An American staple that entered supercar territory has been making waves since its reveal last year. Finally, the second generation Corvette C8 has hit the streets with all that Vette style plus a little more power and exotic appeal.
The Chevy features a 6.2 liter V8 mid-engine that has 495 horsepower and 470 lb-ft of torque, going from 0 to 60 in 2.9 seconds with the Z51 performance package.
The Z51 package adds an electronic limited-slip rear differential, more aggressive brakes and summer tires.
On top of its impressive specs, it’s already making history as the first automatic in Corvette history, using an eight-speed dual-clutch automatic transmission.
The striking luxury American icon reaches a top speed of 194 mph and also features a push-button electronic gear selector in the center console, a vertical climate control cluster/strip and a touchscreen with the new Performance Data Recorder that records lap times, track data and more.
If space has ever been a concern of yours in a luxury sports car, this vehicle makes up for that with its front trunk (frunk) and rear trunk.
With all this, the starting price of $59,995 begins to sound like a real bargain.
When Tesla revealed its first pickup truck to the world, the Internet went crazy. The Cybertruck could be the truck of the future. And they’re not only giving us one Cybertruck, they’re giving us three: the Single Motor RWD, Dual Motor AWD and Tri Motor AWD.
Each model differs in performance but shares similarities in physical attributes. While it looks like a space-age life-size toy car, the truck is actually made to suit an active lifestyle. For example, there’s a 6.4-foot cargo bed hidden beneath a seamless automatic covering that can be removed with a push of a button. The slide-out tailgate even doubles as a ramp to load four-wheelers and motorcycles. For extra space, it also features a frunk.
The exoskeleton is made from Ultra-Hard 30X Cold-Rolled stainless-steel structural skin and Tesla armor glass making it “nearly impenetrable.” The minimalistic interior lets its technology speak for itself with a 17-inch touchscreen horizontally mounted in the center of the dashboard.
And, of course, they will have a 250-kW charging cable and access to Tesla’s network of superchargers.
The unparalleled performance of the pickup truck is obvious. The “Plaid” is rumored to generate up to 800 horsepower and 1,000 lb-ft. of torque, while the Tri Motor AWD’s 0-to-60 is comparable to that of a Ferrari at 2.9 seconds and can reach top speeds of 130 mph – with a range of 500+ miles.
Production will begin in late 2021 with a starting price of $39,000.
Lamborghini SIÁN Roadster
Lamborghini’s most powerful car yet and first hybrid will be unleashed soon. Meet the Sián Roadster – only 19 will be produced and all are already presold.
The Sián, meaning “flash” or “lightning” in Italy’s Bolognese dialect, was rightfully named because of its top speed of 217 mph, reaching 0 to 60 in 2.9 ticks. Producing a whopping 808 horsepower and 531 lb-ft of torque, the 6.5 liter V12 engine is paired with an electric motor that doesn’t fall short. Instead of a traditional battery to power the electric motor, it uses supercapacitors to accumulate and discharge energy. Think all hybrids sound the same? It’s safe to say the unmistakable Lamborghini sound is very present through its dual exhaust.
The open-top hybrid sports car’s build contributes to its overall speed, too. That includes aerodynamic efficiency due to the ultra-light body and low front and carbon fiber monocoque with aluminum front and rear frames. Worth mentioning is the patented smart material that allows dynamic functionality without support of an electric or mechanical engine.
Personalization is key for this supercar. The newly designed air vents are produced by 3D printing, which allows for a client’s initials to be incorporated into the design. The Lambo team at the Centro Stile and the Ad Personam department also works with customers closely to fully customize their Sián to their liking. Speaking of, the Italian brand launches their new hybrid-only Blue Uranus exterior color and Pro Electrum (gold) interior accents with its debut.
Priced at more than $3 million, this is no ordinary sports car.


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The Electronic Sports League will test pro Counter-Strike players for cannabis and other banned substances at the $250,000 ESL One Cologne later this month. Eurogamer reports that the decision is a first for e-sports drug testing, though the ESL is only banning the use of cannabis during the competition. So, puff puff pass before and after, apparently!
ESL will administer random saliva-based tests. Punishments for testing positive include deductions in tourney points and prize money, disqualification, and a two-year ban from ESL events.


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The Bee Gees Show - One Night Only
01 Apr 2023 - Capitol Theatre
Presented by Premier Entertainment
One Night Only is a celebration of the timeless music of The Bee Gees. With record sellout performances around the country, this truly magical concert experience honours their musical and vocal brilliance with all the fun and energy that The Bee Gees were famous for.
One Night Only is an authentic and heartfelt tribute to the brothers Gibb and their magnificent career, gifting the world with songs that have captured the hearts of generations.
Backed by a first class band, audiences everywhere sing along and are up dancing, loving the big hits and three part harmonies that are the essence of The Bee Gees.
One Night Only includes some of the greatest disco hits and beautiful ballads penned by the brothers Gibb including Staying Alive, You Should Be Dancing, Tragedy, Night Fever, To Love Somebody, Lonely Days, More Than A Woman, How Deep Is Your Love and many more.

domain: artistic


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AB2874      Source of Strain:
F- Chromosomal Markers: Δ(gpt-proA)62
, tfr-3Strain Comments:
- This strain can be grown on Phe, Tyr, Try plus shikimic acid at 10-6M.
- glnX44(AS)-- Mutation is a C to T transition at nucleotide 34 (3rd position of the anticodon)
- galK2(Oc)-- is a GAA(glu) to TAA(ochre) mutation, residue 134. Oller et al.1993. Apparently non-suppressible, since all revertants found were at the ochre site.
- Δ(gpt-proA)62 was formerly called proA2
- galK2(Oc) was formerly called gal2
- glnX44(AS) was formerly called su+II
- glnX44(AS) was formerly called supE44
- glnX44(AS) was formerly called glnV44
- thiE1 was formerly called thi-1
- AS = amber(UAG) suppressor
- Oc = ochre(UAA) mutation
- Wallace, BJ, J Pittard 1967. Genetic and biochemical analysis of the isoenzymes concerned in the first reaction of aromatic biosynthesis in Escherichia coli. J. Bacteriol. 93(1):237-44.

domain: chemistry


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Vidya Balan is an Indian actress. She has established a career in Hindi films and is the . The film, an adaptation of Sarat Chandra Chattopadhyay’s novel of the same name, narrated the love story of an .. “with tremendous commitment to the part, [Vidya] gives us a stirring performance free of vanity or obviousness” and. Vidya Balan is an Indian actress known for her work in Bollywood films. She made her acting From Wikipedia, the free encyclopedia her first Hindi film, which was an adaptation of Sarat Chandra Chattopadhyay’s novel of the same name. Top 10 Vidya Balan Movies. by saagarseth | created – 8 months ago | updated – 8 months ago | Public. Refine See titles to watch instantly, titles you haven’t rated.
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Application of Design of Experiment Method for Thrust Force Minimization in Step-feed Micro Drilling
AbstractMicro drilled holes are utilized in many of today’s fabrication processes.Precision production processes in industries are trending toward the use of smaller holeswith higher aspect ratios, and higher speed operation for micro deep hole drilling. However,undesirable characteristics related to micro drilling such as small signal-to-noise ratios,wandering drill motion, high aspect ratio, and excessive cutting forces can be observedwhen cutting depth increases. In this study, the authors attempt to minimize the thrustforces in the step-feed micro drilling process by application of the DOE (Design ofExperiment) method. Taking into account the drilling thrust, three cutting parameters,feedrate, step-feed, and cutting speed, are optimized based on the DOE method. Forexperimental studies, an orthogonal array L27(313) is generated and ANOVA (Analysis ofVariance) is carried out. Based on the results it is determined that the sequence of factorsaffecting drilling thrusts corresponds to feedrate, step-feed, and spindle rpm. Acombination of optimal drilling conditions is also identified. In particular, it is found in thisstudy that the feedrate is the most important factor for micro drilling thrust minimization. View Full-Text
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Kim, D.-W.; Cho, M.-W.; Seo, T.-I.; Lee, E.-S. Application of Design of Experiment Method for Thrust Force Minimization in Step-feed Micro Drilling. Sensors 2008, 8, 211-221.
Kim D-W, Cho M-W, Seo T-I, Lee E-S. Application of Design of Experiment Method for Thrust Force Minimization in Step-feed Micro Drilling. Sensors. 2008; 8(1):211-221.Chicago/Turabian Style
Kim, Dong-Woo; Cho, Myeong-Woo; Seo, Tae-il; Lee, Eung-Sug. 2008. "Application of Design of Experiment Method for Thrust Force Minimization in Step-feed Micro Drilling." Sensors 8, no. 1: 211-221.


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I don’t really like fruit although I love veggies. Any ideas to painlessly get more fruit in my diet?
Both fruits and vegetables offer a variety of vitamins, minerals, and beneficial compounds. Therefore, if you love vegetables, you are probably meeting your daily recommendation for vitamins and minerals. Try a variety of different fruits (there are over 100 varieties in our database), add them in with vegetables you already love, or choose fruits with a milder flavor, such as pears, cantaloupe, or mangos. Smoothies are a great way to meet your daily recommendation for fruit, or add raisins and nuts for a sweet and salty antioxidant packed treat (see recipe)!


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- New Museum Project
- Temporary Exhibits
- Online Exhibits
The bronze statue that stands inside the gate to the Alyeska Pipeline Terminal shows five people who represent the workforce that built the Trans-Alaska Pipeline. In October of 1975, construction activity on the pipeline peaked. During that month just over 28,000 people were employed on the project. They worked as laborers, engineers, administrators, office workers, drivers, communications specialists, electricians, drillers and in many other professional, skilled and unskilled positions. Over the entire course of pipeline construction from 1969-1977, approximately 70,000 people were employed on the project.
The statue’s creator, Malcolm Alexander, attempted to show at least some of the many faces of the pipeline’s workforce. For example, he included a woman teamster. During pipeline construction the percentage of women on the workforce ranged from 5% to 10%. This was a time when the modern women’s movement was gaining momentum. About half of the women working on the project held non-traditional blue-collar jobs.
The statue also includes an Alaska Native worker. Minority workers made up 14-19% of the workforce.
Many people on the workforce came from outside of Alaska. However, Alaskans were also employed on the project. A number of local Valdezans went to work in the pipe yard, as teamsters, and on the construction of the terminal facility itself.
Where are the people who helped build the pipeline today? Many, of course, remained in Alaska, including Valdez. The Valdez Museum has gathered information from former pipeline workers from far and wide, from Yokohama, Japan, to Hebron, Connecticut — and many, many other places.


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Our Rivers' Story
The Early Inhabitants of the Valley
Centuries before the area was settled by whites, at least two different native tribes inhabited the St Joseph Valley.
The Miami were the first recorded tribe known to have lived in the valley before 1668. The main village was located east of the St. Joseph River at the present day site of Niles, Michigan. Other villages were recorded in present day South Bend and Waterford Mills, Indiana.
The Miami were present when, in 1678, French explorer, Sieur de LaSalle, made the portage from the St. Joseph River to the Kanakee River on his journey to find the mouth of the Mississippi River.
Little is known why the Miami left the valley. Some speculate they were driven out by other more aggressive tribes. Others say they sought a better trading center near Fort Wayne, Indiana. For whatever the reason, by 1706 the Miami ceased to inhabit northern Indiana.
Early in the 1700's the Potawatomi began their migration from Wisconsin to the St. Joseph Valley by way of the St. Joseph River. This band of native Americans spread out over much of southern Michigan and northern Indiana. They were known as the St. Joseph River Valley Potawatomi.
The best known village was located west of present day Niles, Michigan. This village was home to Chief Topenebee, one of the area's most influential leaders. Although Topenebee had joined Tecumseh in an uprising against the white settlers, there is no indication that he ever harmed them. In fact, he was credited with helping some settlers survive the Massacre of Fort Dearborn (Chicago).
Another well-known Potawatomi village was located on the Elkhart River near Benton in the southern part of Elkhart County. Known as Aubeenaubee, it was home to Chief Five Medals. Destroyed in 1812 by American troops in retaliation for Five Medals' attack on Fort Wayne, it appeared the inhabitants escaped unharmed, having fled the village just before the troops arrived.
The population of the St. Joseph Valley Potawatomi began to diminish as white settlers moved westward into the territory. Some natives died of disease brought to the area by settlers, others migrated to Illinois, and with a few exceptions, others were being forcibly removed by the U.S. government. By the 1830's, there is little documentation of any native American villages left in the Elkhart area.
The Sohgwohsebe and Mishiwa-Teki-Sipiwi Rivers
The rivers in the St. Joseph Valley played an important role to the native peoples. The St. Joseph River, or as the Potawatomi named it, the Sohgwohsebe River, was a migration route that could be traveled north to Lake Michigan or south by portaging to the Kanakee River. The Mishiwa-Teki-Sipiwi (Elkhart River) served as a landmark to establishing the important Fort Wayne Trail.
As we know, all settlements needed water sources not only for drinking purposes, but for food and shelter materials. These rivers provided fish, turtles and crawfish. In addition, the rivers attracted waterfowl, deer and bear that made up the daily diet of the valley residents.
The French Traders Come to the Valley
Before the arrival of the French traders, the Native Americans were self-sufficient. The men spent their days hunting and gathering food, while the women were busy tending to small gardens and fashioning clothing. But by the late 1600's, with the growing demand for fur in Europe, French traders began traveling the rivers to barter trinkets or hard-to-come-by items to the natives for valuable pelts. Soon this daily routine was replaced with the priority of trapping fur-bearing animals for trade. This over-hunting would have a detrimental ending with the animal population being depleted.
One of the first trading posts in the area was built by Joseph Bertrand. Joseph established the post in 1808 on the St. Joseph River just south of present day Niles, Michigan. The post thrived because of its close proximity to the river and the Sauk Trail (see Early Trails).
Even before LaSalle traveled up the St. Joseph River, French Jesuit missionaries had been converting the Potawatomi to Christianity. They had moved with the natives as they expanded their territory into the valley. In 1823 Isaac McCoy, a Baptist Missionary, established the Carey Mission near the village Topenebee and Niles, Michigan. As Isaac and his wife traveled from Fort Wayne to Niles, they forded the St. Joseph River east of Island Park. It was there that Isaac discovered the mouth of the a creek that emptied into the river from the north bank, because of its beauty, he named in in remembrance of his wife, Christiana.
The Last Act
In the Chicago Treaty of 1821, Chief Pierre Moran was awarded one section of land at the mouth of the Elkhart River. This area included Island Park and much of the present day downtown. Chief Pierre Moran sold that property to Dr. Havilah Beardsley in 1831 and the village of Elkhart was born.


Smart payments company Coin this week announced the shutdown of its various product services, officially closing product support, social media channels, and the connected Coin app on iOS and Android devices on February 28, 2017. The news follows the discontinuation of all Coin products last May, when Coin was acquired by Fitbit and the company subsequently ceased selling its line of smart payment cards.
With no new Coins available to purchase and its services shutting down, users will no longer be able to add new cards to the device without the mobile app being supported. Coins themselves will continue to work until their batteries die (two years from initial activation), so the company is encouraging users to add any cards they want before February 28.
With the acquisition of Coin by Fitbit, all business operations ceased on June 13, 2016. The company is no longer manufacturing, promoting, or selling any new devices or products.
Effective from February 28, 2017, the Coin product services will officially be shut down. As a result, support through the Coin website or through social media channels will no longer be available.
The original Coin, as well as Coin 2.0, was a single credit card-sized device that stored a collection of credit and debit cards that users could toggle through with a small button on the front of the Coin. Once the desired card was selected, users swiped Coin like any normal payment card, and the charge went through to whatever card was chosen.
Coin was first announced and began receiving orders in 2013, one year before Apple would launch Apple Pay in 2014, but Coins didn't begin arriving to customers until 2015. Although Coin's shutdown has been clear since the Fitbit acquisition last year, the growing popularity of smartphone mobile wallets like Apple Pay and Samsung Pay undoubtedly became large competitors to Coin's business in 2015 and 2016.
In Fitbit's own press release last year, the company described a deal that focused on the specific acquisition of "Coin's wearables payment platform," although at the time there were "no plans to integrate Coin's wearable payments technology" into its 2016 roadmap. That still leaves future Fitbit devices in 2017 and beyond wide open for an "active NFC payment solution."
Amid acquisitions of Pebble and luxury watch maker Vector Watch, Fitbit has faced lower-than-expected revenue results for the fourth quarter of 2016, leading to cuts of between 5 to 10 percent to its workforce. With Apple Watch gaining ground in the smartwatch space, Fitbit appears to be gearing up to launch a more feature-rich wearable with its own app store, mobile wallet, and more, instead of the activity-focused wearables it currently sells.


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domain: pet


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By: Settu Shankar
Thursday, July 05, 2007
After his last Tamil release Muni, choreographer turned director Raghava Lawrence is preparing to direct another Tamil film. His new Tamil film will be titled Pandi. Like his last film Muni, he will act in this one too. Nemichand Jabak will produce the film, who has Naan Avanillai to his credit.
Presently, Raghava Lawrence is busy with Nagarjuna movie Don, a remake of the Bollywood version of Don. The former dance master said, "Directing a movie in my own mother tongue is always a joy. Though I have attained good success with my Telugu films, I want to deliver the same in Tamil. Muni is a hit movie. I can't really say that it is a blockbuster. I hope that Pandi will fulfill my wish of delivering a blockbuster.

domain: entertainment


BY ELIZABETH MEYER
Special to Pen City Current
FORT MADISON — The Fort Madison school board on Monday got an update from DLR Group on Phase 1 of the project to expand the middle and high school buildings as the district moves toward its completion date of August 2023.
The Des Moines-based DLR Group provides architectural services for the project and Burlington’s Carl A. Nelson Co. oversees construction management. Phase 1 includes expanding the high school building to accommodate 7th-12th grade students (the building currently holds grades 9-12) and adding on to the middle school so it houses Pre-K through 6th grade, up from the current 4th-8th grades. Once the project is complete, Lincoln and Richardson elementary schools will no longer be in use.
Monday’s presentation represented the “pre-design” stage of the project. DLR Group will attend the school board’s next regular meeting on Aug. 16 to present the “schematic design.”
The board voted unanimously to approve the pre-design concept.
“This pre-design phase is really to gather as much information as we possibly can and then starting to mold that into what this space is going to be,” said DLR Group’s Nick Hansen, noting he recently spent several hours with the district’s elementary and middle school teachers learning what they would like to see in the new facilities.
“Next board meeting we’ll be presenting our schematic design,” Hansen said. “You’ll be able to see things that are a little bit more, I’ll say, written with a pencil; you can still erase a little bit, but it will start to get more real.”
Phase 1 will be paid for by borrowing SAVE (Secure an Advanced Vision for Education) funds and utilizing the district’s Physical Plant and Equipment Levy. Tapping into these existing revenue streams required voter approval but does not require additional taxpayer support.
“In 25 months, we will have kids walking in that door and we’re all going to celebrate,” Hansen said.


The timeline for the DOGE-1 mission remains unclear.
DogeDesigner (@cb_doge), in a tweet today, has confirmed that the DOGE-1 mission to the moon will not launch before March 1, 2023, citing persons familiar with the project.
DOGE-1 Mission will launch no earlier than March 2023, as confirmed by @SamuelReidGEC @GeometricEnergy @YourTimeInSpace
This mission is completely funded by Dogecoin, thus becoming the first space mission funded by a cryptocurrency. pic.twitter.com/cMWk0yL9lF
— DogeDesigner (@cb_doge) December 31, 2022
While it still leaves no clue about the date of the space mission, it puts to bed potential speculation that DOGE-1 will be among the 114 satellite payloads on the first Falcon 9 mission in 2023, announced by SpaceX yesterday. Notably, the first SpaceX launch for 2023 is scheduled for Tuesday next week.
There are 114 payloads on this flight, including CubeSats, microsats, picosats, and orbital transfer vehicles carrying spacecraft to be deployed at a later time
— SpaceX (@SpaceX) December 30, 2022
The Crypto Basic saw the first Twitter mention of the March 2023 timeline from Geometric Energy Corporation CEO Samuel Reid on November 28. Reid also reiterated it on December 12. This gives credence to the information shared by the Dogecoin Foundation graphics designer today, as Geometric Energy will lead the mission.
Yes, DOGE-1 is NET (No Earlier Than) March 1, 2023
— SΔMUΞL RΞIÐ (@SamuelReidGEC) December 12, 2022
DOGE-1 is a cubic satellite that promises to obtain information about the moon using sensors and cameras. It represents the first commercial payload fully funded by cryptocurrency. With the mission, Elon Musk’s SpaceX hopes to demonstrate the utility of crypto in space.
Musk announced the mission in May last year, feeding into the bullish DOGE to the moon narrative. While the mission was supposed to launch this year, persons close to the matter have asserted that the delay is due to the lack of readiness of the Intuitive Machines satellite, which is the primary payload.
According to Reid, in April, DOGE-1 will get to the moon when IM-1 does.
Thank you! Though to clarify, the Geometric-1 Mission to Earth Orbit which includes the display screen in a cubesat (not yet to the moon) is October 1, 2022, whereas the DOGE-1 Mission will reach the moon when IM-1 does which is to be announced when it will happen. #DOGE-1
— SΔMUΞL RΞIÐ (@SamuelReidGEC) April 1, 2022
Notably, DOGE-1, which could have a potential bullish impact on the Dogecoin price, was one of the motivations for popular DOGE influencer Matt Wallace to bet his YouTube channel on DOGE, clinching the $1 price point in 2022.


The four victims from the boating accident off of Dinner Key on the Fourth of July have been identified, all of which are young adults.
Authorities in the Bahamas are investigating a boating accident that left a 25-year-old from Key Biscayne dead.
Two teenage girls are recovering after the inner tube they were riding hit a piling Friday night around 7 p.m.
A Florida man was severely hurt in the Florida Keys trying to push a stuck boat.
MIAMI (CBSMiami)–When a boat capsized sending 30 people and a dog into the water off Key Biscayne, South Florida law enforcement agencies were ready. They were out in full force this Columbus Day weekend. “We […]
Thirty people and one dog were rescued from the water Sunday after a 45-foot catamaran capsized near the Miami Seaquarium.
Two people were killed in a boating accident near a Clearwater causeway on Saturday.
Dive team and fire boat crews responded to a boat accident near Jungle Island Friday morning.
A body recovered on Miami Beach early Sunday morning was that of a missing boater.
A couple is recovering after they were involved in a hit and run crash on the water Saturday evening.


Rock Island has always been a reliable brand for firearms. They have produced some of the best handguns in the market, and the 10mm is no exception. However, like all guns, the Rock Island 10mm does have its share of problems. In this blog post, we will discuss some of the most common issues with this firearm. We will also provide solutions to help you overcome these problems.
Rock Island 10mm problems
One of the most common problems with the Rock Island is that it is not very accurate. This is due to the fact that it has a short barrel. The shorter the barrel, the less accurate the gun will be. There are several ways to overcome this problem. One way is to get a longer barrel. Another way is to get a better quality trigger. Either way, you should be able to improve the accuracy of your Rock Island significantly.
Another common problem with the Rock Island is that it can be difficult to cock the hammer. This is because the hammer needs to travel a long distance in order to cock the gun. There are two ways to solve this problem. One way is to get a stronger spring for your hammer. Another way is to get a shorter hammer. Either way, you should be able to make it easier to cock your Rock Island.
The last problem we will discuss is that the Rock Island can be difficult to disassemble. This is because there are many small parts that need to be removed in order to disassemble the gun. The best way to overcome this problem is to get a good quality set of gunsmithing tools. With the right tools, you should be able to easily disassemble your Rock Island.
As you can see, there are several common problems with the Rock Island. However, these problems can all be overcome with a little bit of work. If you are having trouble with your Rock Island, don’t hesitate to reach out to a gunsmith. They will be able to help you solve any problems you may be having.
Are Rock Island 10mm any good?
Yes, Rock Island Armory makes very good quality pistols. The company has a great reputation for making reliable and well-crafted firearms. I have never had any problems with any of my Rock Island pistols. They are accurate and have always performed flawlessly. I would highly recommend them to anyone looking for a good quality firearm.
Are Rock Island guns reliable?
This is a question that gets asked a lot, and the answer is yes… and no. Rock Island guns are definitely reliable, but there have been some reports of issues with them. Overall, though, they are a reliable gun brand.
One thing to keep in mind is that Rock Island guns are not always the easiest to find parts for. So, if you do have an issue with your gun, it might be difficult to find someone who can fix it. But, if you’re willing to do a little research, you should be able to find what you need.
Overall, Rock Island guns are a great option for those looking for a reliable gun brand. Just make sure you do your research before buying one so you know what you’re getting into.
Are 10mm 1911 any good?
The short answer is yes, they are. The slightly longer answer is that they can be, but it really depends on the gun in question and how it’s been put together. A lot of people think that because a gun is chambered in .45 ACP, it’s automatically going to be a good gun. That simply isn’t the case. There are plenty of .45 ACP guns out there that are complete garbage. The same goes for any other caliber or platform, for that matter. It all comes down to quality control and the individual gun itself.
With that said, there are definitely some very good options when it comes to choosing a quality ten millimeter 1911 pistol. Here are just a few that come to mind.
The first is the Kimber Custom TLE II. This is a full-size gun that weighs in at 41 ounces, making it a bit on the heavy side for some people. However, the weight does help to mitigate recoil, which can be an issue with the larger caliber. It has a five-inch barrel and an overall length of eight and a half inches. The capacity is eight rounds plus one in the chamber.
Another great option is the Colt Delta Elite. This one is also a full-size gun, but it’s slightly lighter than the Kimber at 39 ounces. It has the same five-inch barrel and overall length as the Kimber, but its capacity is ten rounds plus one in the chamber.
And last but not least, there’s the Smith & Wesson 1911 SC ( Scandium) E-Series. This one is a bit different than the other two in that it’s a compact gun. It weighs just 33 ounces and has a shortened barrel length of four inches. The overall length is seven and a half inches. Its capacity is eight rounds plus one in the chamber.
So, there you have it. Three great options for quality ten millimeter 1911 pistols. As always, make sure to do your own research before making any final decisions.
Rock Island 10mm vs Glock 20
The Glock 20 is a tried and true design that has been around for decades. It is a reliable gun that is chambered in the powerful .45 ACP round. The Rock Island Armory 1911 Tactical II is a newer gun that is chambered in the slightly less powerful but still potent .40 S&W round. Both of these guns are great choices for self-defense, but which one is the better option?
The Glock 20 has more stopping power than the Rock Island Armory 1911 Tactical II because it is chambered in the .45 ACP round. The .45 ACP round has been used by law enforcement and military personnel for many years, and it has a proven track record of being an effective self-defense round. The .40 S&W round is a good self-defense round, but it does not have the same level of stopping power as the .45 ACP.
The Rock Island Armory 1911 Tactical II is a newer gun, and it has some features that the Glock 20 does not have. The Rock Island Armory 1911 Tactical II has an ambidextrous safety, and it also has a beavertail grip safety. These two features make the Rock Island Armory 1911 Tactical II a more user-friendly gun than the Glock 20.
The bottom line is that both of these guns are great choices for self-defense. If you are looking for a gun with more stopping power, then the Glock 20 is the better option. If you are looking for a gun that is easier to use, then the Rock Island Armory 1911 Tactical II is the better option.
Check Also: Glock 21 Gen 4: Overview and Problems


- An excited Rouge has bagged a new sponsorship deal with a popular sports nutrition brand, USN South Africa
- The rapper shared that she's happy to be part of the brand's family and can't wai to start her new journey with the company
- The fans of the One by One hitmaker, who is known for living a healthy lifestyle, took to her comment section to congratulate her for signing the deal
Rouge has taken to social media to announce her partnership with a popular sports supplement and nutrition brand. The rapper, who usually posts videos of herself working out, shared that she's excited to be part of the USN South Africa family.
"ANNOUNCEMENT. Proud to announce that I've joined the @USNSA family!! We getting these deals in silence. Now let's build."
The award-winning musician's fans took to her comment section to congratulate her for bagging the new deal. Check out some of the reactions below:
"Congratulations. I've been dreaming about joining them since I started using their stuff 4 years ago."
"Congratulations. You deserve it and umuhle (you're beautiful) tooooo much. You're dope."
"I can boldly say you're not from this planet called earth, you're damn beautiful."
"Congratulations. You're literally bagging all these deals."
Cassper Nyovest signs R100m sneakers deal, internet blows up
Cassper had hinted earlier during the day that he had some big news to announce but no one had any idea that it would be this big. The deal was signed on the tallest building in Africa, The Leondardo Hotel, to mark the magnitude of the contract.
Cassper and the founder of Drip Footwear Lekau Sehoana held a press conference on top of the building. Sehoana signed an equity partnership deal with Nyovest, real name Refiloe Phoolo. He posted a video online saying that his hard work had finally paid off as he was driving through Johannesburg in a Bentley. He revealed that when he'd first arrived, he'd come to the city in the back of a van.
Enjoyed reading our story? Download BRIEFLY's news app on Google Play now and stay up-to-date with major South African news!
Source: Briefly News


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Strategic Alliances for a Secure, Connected, and Prosperous Region
Author: Ehud Rosen
Ehud Rosen specializes in modern political Islam, focusing on the ideology and history of the Muslim Brotherhood. He received his PhD from SOAS, University of London. He is currently a senior researcher at the Jerusalem Center for Public Affairs.


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Amylyx announces plans to submit a Health Canada application in early 2021
March 9, 2021 – Today Amylyx announced plans to submit a New Drug Submission (NDS) to Health Canada in the first half of 2021 for its AMX0035 therapy. In addition, the company will explore options for early access to AMX0035 in Canada, including a potential special access program (SAP), and aims to finalize plans by the end of the second quarter of 2021.
We know this therapy is of interest to many in the ALS community. And while this announcement does not yet mean the drug is available in Canada, Amylyx’s decision to pursue regulatory approval and a special access program is a promising milestone for the Canadian ALS community.
If Health Canada accepts the NDS application, the next step would be a thorough review, which we hope will be conducted within a six-month priority review. You can read more about Health Canada’s process on their website.
As our community knows all too well, Canadians living with ALS do not have the luxury of time. There is an urgent need for people living with ALS to have access to proven, effective therapies. We hope to see the momentum continue in meaningful ways that will make a difference to Canadians living with the disease.


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Discover the Best Bitcoin Poker Sites: Where Crypto Meets Cards
If you have been an avid fan of Bitcoin poker, you already know that the market saturation is running at an all-time high. A large number of new and flashy Bitcoin poker sites are popping up daily, making it somewhat difficult to easily find the best poker sites for your liking.
Merging poker with blockchain technology has already proved to be a massive success, offering a variety of benefits specific to crypto poker. Although traditional poker is not going away, Bitcoin poker has already been established as the most exciting addition to the game.
If you are on the hunt for the best bitcoin poker sites, this article is for you. You could also check out Coin Poker. We will be diving into the basics of Bitcoin poker, the benefits of playing it, and tips and tricks on finding the best poker sites out there in 2023. Without further ado, let’s get into it.
Best Bitcoin Poker Sites in 2023
While there are endless poker sites to choose from luring you in with flashy offers, you should be careful when making this choice. Picking a good, trusted, and reliable Bitcoin poker site is important, although the choice is ultimately a personal preference.
A widely trusted and reliable site, CoinPoker is one of the best legit cryptocurrency casinos out there right now. Bear in mind that it has an RGN decentralized system, confirming that you are getting a fair-game experience every single time that you decide to play here.
An important reason why many people opt for CoinPoker is the fact that it is incredibly easy to access, has many community promos, and an astonishing fast payment processing. In addition, it offers blockchain-based safety to all of its players.
A new addition to the highly-sought poker sites, Coinzino has already amassed a great number of fans. It offers games such as blackjack, roulette, poker, slots, and many more. All in all, it is a new Bitcoin casino that offers more than 3,000 games to choose from.
This page offers a chance to win a 100% welcome bonus following your first deposit, and 10% on the losses you have while playing. It also has a great live game selection. If you are stationed in the U.S., keep in mind that you can’t play here unless you get yourself a VPN.
Lucky Block Casino
This particular online casino will have you enjoying a variety of games, such as Indian Poker, Oasis Poker Classic, Poker Lobby, and several others. This website is suitable for all types of players and skill levels, including amateur and professional players, part–time and VIPs.
Another interesting thing about it is the fact that the experience almost feels as if you are sitting in a real casino, with great graphics that the site offers. Registration is also very easy, as it is easy with CoinPoker. Keep in mind that it, however, does not have live poker.
Reasons to Play Bitcoin Poker
If you think about it, online poker is not an entirely new thing. For example, online poker variants such as the popular Texas Hold’em have been around for years. However, crypto poker is an entirely new and exciting experience for professionals and casual players alike.
As a whole, this take on poker is interesting for several reasons, the first of which would be the fact that it relies on the use of cryptocurrencies instead of fiat currencies, such as dollars. In essence, you deposit, play with, and withdraw your finances through Bitcoin. This means that you avoid the usual hassle you have with your bank due to playing.
Convenience and Availability
The second most obvious difference between Bitcoin and traditional poker is that there is no usual hassle of getting up, driving to a casino, and everyone seeing your face as you play. Bitcoin poker is always available and easily accessible, regardless of where you are.
If you have still not mastered a good technique for your poker face, which is one of the more important elements in finding poker success, you will be relieved that a good poker face plays no factor in Bitcoin poker. You do not show your face online, so it doesn’t concern you.
Your data, due to the implementation of blockchain technology, is safer than it has ever been before and you are less susceptible to issues such as bank meddling and any type of fraud and data theft. Unlike traditional poker, your transactions are extremely fast and fully digital.
Low Fees and High Winnings
Another benefit of playing Bitcoin poker is that the fees are generally lower than those charged by traditional poker sites. This means that players can keep more of their winnings and can also enter tournaments with lower entry fees, giving them the opportunity to win bigger payouts.
Moreover, Bitcoin poker rooms often offer higher bonuses and rewards to their players due to the lower overhead costs associated with using cryptocurrency. These bonuses can range from deposit bonuses to freerolls and can significantly boost a player’s bankroll.
Provably Fair Gaming
One of the most significant advantages of Bitcoin poker is the concept of provably fair gaming. This concept ensures that the results of every game are entirely random and cannot be tampered with by either the player or the operator.
Provably fair gaming is achieved through the use of cryptographic algorithms, which allow players to verify the fairness of each hand or game played. This level of transparency and fairness is not present in traditional poker games, making Bitcoin poker a more trustworthy and reliable option.
In summary, Bitcoin poker offers several benefits over traditional poker games, including financial autonomy, convenience and availability, anonymity, data protection, low fees and high winnings, and provably fair gaming. These factors make Bitcoin poker an attractive option for both casual and professional players who are looking for a more innovative and secure way to play poker online.

domain: hobby


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Here's a little bit about my experience recovering at home after my Lasik procedure at TLC Laser Eye Center. The first day, I continued to wear those snazzy, sunglasses that help protect my newly-corrected (is that a real phrase?) eyes from sunlight and bright lights in general. I was told to avoid T.V. Computer, tablet and cell phone screens that first day as well. It definitely helps with the healing process. Plus, I'll be honest, it was nice to take a break from all of those screens that seem to take up so much of our time and attention these days. I mainly just rested (read: slept) and about every two hours while I was awake, I would take an antibiotic eye drop followed by a steroid eye drop, which aids in healing and making the cornea strong again. Keeping the eyes lubricated is key in the recovery so I also did an over the counter eye drop every hour as well. As long as you are diligent about the instructions they send you home with, it really is an easy process.
The Doctors and techs at TLC are very clear about possible issues like dry eyes, burning sensation or some irritation in the first few hours after the procedure. But in MY experience, these symptoms were all very minor and continually using the drops alleviated any discomfort. I could see things too, like the clock in my bedroom without glasses or contacts for the first time ever. It was crazy. I awoke the next morning and my vision had improved from the night before and my eyes felt much better. I looked out the window and was shocked at how clear everything was. I then got to go to my own eye doctor nearby for a 24-hour follow up so she could see how things were already healing up. I was reading the eye charts at better than 20/20 and was amazed with the results. Below is some video my wife shot after I was cleared to drive....the NEXT DAY


Then there are the antitrust probes. As Google has grown larger and its commanding share of the Web search market has solidified, it has drawn ever closer scrutiny from antitrust regulators, both in the United States and abroad. The Federal Trade Commission has probed Google over its purchase of mobile ad provider AdMob, its acquisition of travel industry software maker ITA, and an ad-sharing partnership with Yahoo. The first two deals were approved; the last was not. The agency now says it is ready to press forward with a more formal antitrust investigation, citing questions about Google's search and advertising businesses. European regulators launched a similar investigation in November.
Individuals can't innovateNone of this bodes well if you're a Google staffer with big ambitions. Famously, Google engineers are encouraged to spend 20% of their hours working on what they think will most benefit the company, irrespective of their regular duties. But as Google has grown more cautious and its management structure has grown more rigid, 20 Percent Time projects are less and less likely to become full-fledged products. Larger development teams have become the norm, and decisions require countless rounds of meetings and conferences. In 2009, former CEO Eric Schmidt observed, "There was a time when three people at Google could build a world-class product and deliver it, and it is gone."
Little wonder, then, that Google has gradually scaled back its commitment to 20 Percent Time. In 2008, Valleywag reported that managers were curbing the practice when mission-critical projects fell behind schedule. This year Google shut down Google Labs, a hub that allowed the public to experiment with 20 Percent projects and give feedback.