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Germany’s Evotec has penned another deal amid a stream of R&D pacts over the past year, this time with PARP player Tesaro.
The CRO-biotech hybrid, which is increasingly becoming biotech focused, has signed a three-year integrated drug discovery collab with Tesaro. The pact is centered on finding new small molecule product candidates against an undisclosed immuno-oncology target. Financial terms were not disclosed.
This also comes the same day that Tesaro gained FDA approval for an intravenous version of its drug Varubi (rolapitant) to treat chemo-induced sickness.
On its side, Evotec will use its drug discovery platform, from lead discovery through the picking of a preclinical candidate, and hook this up to Tesaro’s translational research pipeline in the hope of pushing on with work in what they hope will be best-in-class oncology therapies.
“Tesaro is excited to work with Evotec to expand our discovery capabilities against immuno-oncology targets,” said Jeffrey Hanke, Ph.D., EVP of research and CSO of Tesaro.
Mario Polywka, M.D., COO of Evotec, added: “Oncology is one of Evotec’s core therapeutic areas of focus and we are pleased to enter into this exciting and innovative partnership with Tesaro, a globally recognised oncology leader and one of the fastest growing biotech companies in the USA.
“This collaboration further demonstrates the value of our integrated research site in Toulouse and our world-leading structural biology group in Oxford. Using our integrated drug discovery platform, we are committed to helping Tesaro drive innovation in this very important field of high-unmet medical need.”
This builds on a series of deals coming out of Evotec, including just last week the company’s expanded collab with Forge Therapeutics, which focuses on targeting metalloenzymes.
Last year, it also spun off its first drug unit, an early-stage biotech called Topas Therapeutics that works on tolerizing particles.


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Quilt is finished and ready to be mailed to Ms Ella in Boston, Mass.
The crazy quilt patches are machine quilted with the feather stitch and the rest is free motion stippling and Motifs on the blue border. This was shown in an earlier post. The mice in the outer border were stippled around them to make them stand out.
Knitted baby hat, the first one was way too small.
Thank You for visiting me and love your comments. Looking forward to seeing all the beautiful projects people are working on at Susan Flemming's Super Mom No Cape, Embroidery and Cross Stitch on Monday....http://www.supermomnocape.com

domain: artistic


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Which Oregon hospital stands out above the rest for heart surgery?
If you need heart surgery, Consumer Reports says there’s one hospital in Oregon that stands head and shoulders above the rest.
Kaiser Permanente Sunnyside Medical Center in Clackamas is one of only 15 hospitals nationwide to receive an above-average rating from the non-profit consumer advocacy group, based on outcomes for both coronary artery bypass surgery and aortic valve replacement surgery.
Sunnyside Medical Center also is the only one of nine Oregon heart centers to receive an above average, Consumer Reports said in a new report released today.
Seven other Oregon hospitals received a rating of average:
- Legacy Emanuel Hospital
- Legacy Good Samaritan Hospital
- McKenzie-Willamette Medical Center in Springfield
- Providence Portland Medical Center
- Providence St. Vincent Medical Center
- Rogue Valley Medical Center in Medford
- Tuality Healthcare in Hillsboro
Oregon Health & Science University Hospital was the only one to receive a below average rating, for its coronary artery bypass surgery.
Consumer Reports based its ranking on data from patients’ medical records showing whether they survived the procedure and how they fared on other important measures, including complications.
The non-profit got its data from the Society of Thoracic Surgeons. Although more than 1,000 U.S. hospitals report to the medical society, only about 400 agreed to provide Consumer Reports access to the data.
“It’s extremely difficult for consumers to know which hospitals and surgeons have the best result with their specific heart procedure. But it shouldn’t be so hard,” said Dr. John Santa, medical director of Consumer Reports Health. “Hospitals and doctors should make their information accessible and understandable.”
Consumer Reports cited Portland as one of four metropolitan areas that had both top and low-scoring heart hospitals. The others are Indianapolis, Los Angeles and Oklahoma City.
Dennis Thompson is a contributing health care reporter based in Salem.
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domain: medical


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There are over 500 species of bees in the state of Oregon. A large majority of these species help pollinate the unique crops that grow in Oregon. Honey bee colonies are very large and long lasting hives that can be easily moved to other crops and locations. Farmers are able to rent bee hives from outside businesses or other farmers in order to ensure that their crops are being pollinated at a rate that will provide the appropriate yield of their crop.
Honey bees were brought to America in the 1620s when European settlers came to the United States. Honey bees were and still are sought after for their ability to pollinate many varieties of crops as well as their production of honey.
Apis mellifera, better known as the “Western Honey Bee”, is the most commonly known pollinator to the general public.
Wool carder bees are an exotic breed of bee that are very aggressive and territorial. The bees have five “spines” on their last abdominal and they will use them to bump other bees off of a plant or flower.
Leaf cutter bees are the same size as a honeybee but they have large brushes of hair on their undersides. They also have very large “mandibles” which is a part of their mouth. Leaf cutter bees have their name because they chew round circles in the leaves of plants.
Worker bees hatch from a fertilized egg and are the female bees. After the female bees hatch, they spend around 6 days in the larval stage. In the larval stage, the bees are fed between 150-800 times per day by the adult worker bees. At this time, fat bodies are being built so that the bee has an adequate amount of storage for lipids, glycogen, amino acids and mitochondria for the bee during the pupal stage. After about 8 or 9 days, the cells with these larva are capped and the larva begin to grow. The pupal stage is the most important part of a bees growing period. This is when the wings, abdomen, internal organs, and muscles are begin to form. Like mentioned before, at this point in the growth of the bee is when the fat bodies like lipids, glycogen, amino acids, and mitochondria are used to help the pupa become an adult bee. After 20-21 days in the pupal stage, the bee chews through the capped cell and begins it’s hunt for its first feeding. Once the bee has come out of the cell, it must find food within a few hours or it runs the risk of not becoming a healthy and productive bee in the hive. The first job of the worker bees include things like feeding and cleaning larvae, cleaning the hive cells, building comb, guarding the hive from predators, patrolling the work of other bees, taking pollen from forager bees, or storing, curing, and packing pollen. Worker bees live between 15-38 days in the summer. In the winter time, the very well fed and healthy bees can often live for 140-320 days.
The bee population of a hive is made up of 15% drone bees. Drones are the only male bees in the hive and they hatch from unfertilized eggs. Their diet is similar to that of worker and queen bees except for drone bees’ diet has an increase amount of pollen and honey. The main purpose of drone bees is to mate with the virgin or newly mated queen bee. Drone bees leave the hive six days after emerging from their cell. Drone bees die shortly after they mate with the queen. The average life span of a drone bee is 8 weeks.
Queen bees are also hatched from unfertilized eggs. The only difference between the development of the two bees are what they eat while they grow. The queen bee is fed her diet for the entirety of her development stage. In the final two days of her larval stage honey is added to her diet. This addition increases the sugar content of the diet as well as a hormone called “juvenile hormone.” This hormone helps the female bee when developing the anatomy of a queen bee. Once the queen bee is developed her job is to mate with drone bees and lay eggs for the rest of her life span. The normal life span of a queen bee is normally 2-5 years. In that time period, she will lay around 200,000 eggs a year.
Watch this video on Small hive harvesting – Portland, OR!
Honey is harvested in a pretty simple way. The bee box is opened up and the boards are individually removed. Once the boards are removed, the honey bees are put onto another part of the hive so that the honey can be scraped off. Once the bees are comfortable in their new location in the bee box, the honey is scraped off of the boards to be processed. Honey is processed into jars or glasses for consumers to purchase. Harvesting honey is a fairly easy process but an important thing to remember is to stay calm and move slowly around the bees and the bee box.
Varroa mites are parasites that take over a honey bee hive and feed on the products of adult bees, pupae, and larvae. These Varroa mites can kill individual bees but they can also attack the entire colony causing a whole colony of bees to collapse.
One way to get rid of the Varroa mites is by putting a half cup of bees in a mason jar with 2 tablespoons of powdered sugar. If you shake the jar, all of the mites will fall off of the bees and you are able to rid the bees of any harmful mites.
Small hive beetles have been in the United States since 1998 but they are originally from the sub-Saharan Africa. These beetles can be found in almost all fifty states. The small hive beetle larvae feed on honey and pollen. The adult beetles destroy damaged honey and the honeycombs.
Tracheal mites are microscopic parasites that live in the windpipe of bees. In order to see these mites and determine how many have done damage, you have to use a microscope. If a colony of bees has been infected by tracheal mites, they will begin to die, the live bees will not cluster correctly and the rest of the hive will die during the winter months.
Honey is used as a natural sweetener for things like tea or baked goods and can also be found in medicinal products such as cough syrups or drops.
Raw honey can be used to sweeten drinks such as hot or iced tea and in baked goods like scones or pastries. Raw honey is often eaten by itself as a natural vitamin.
Honey is added to medication like cough syrups because it soothes the irritated part of the body.
Where the queen bee, drone bees and worker bees all live. This is also where the larva grow.
What a bee is called when it hatches from the egg.
Life stage of organisms where transition from immature to mature insect happens.

domain: agronomy


The California Public Records Act has long been a tool for journalists and citizens to learn more about how public officials reach decision concerning public matters. With a simple letter, a member of the public can request that a local government produce documents pertaining to an upcoming vote on a controversial land use project orÂ other public matters. Public officials have long been required to produce communications from their official government-supplied email account in response to these document requests. For many years, a gray area has been whether public officials were required to also review and produce personal emails and text messages pertaining to government business. Â On March 2, 2017, the California Supreme Court issued an opinion confirming that a public officialâ€™s personal email and text messages can be â€œpublic recordsâ€ for purposes of a Public Records Act request. Â The decision, City of San Jose v. Superior Court, (Mar. 2, 2017 S218066). Â This decision is a game changer for transparency in government proceedings. Public officials can no longer prevent the public from accessing the full spectrum of communications officials have pertaining to government affairs.
This post is the latest in a series of posts on the First Amendment and transparency in government.Â Â Jeffrey LewisÂ and the other attorneys atÂ Broedlow Lewis LLPÂ are experienced attorneysÂ and can advise you about your potential rights concerning access to public records.Â Â Each case is different and you should consult a lawyer rather than relying on this post as legal advice for your situation.


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Health Law Attorney Email List
Health Law Attorney Email List
Unlocking Opportunities with the Health Law Attorney Email List. The healthcare and legal sectors are intricately connected, and for law firms specializing in health law, reaching out to potential clients and collaborators is essential. The Health Law Attorney Email List – Health Law Attorneys Mailing Database provides an indispensable resource for such law firms and lawyers marketing companies to tap into this specialized field. Let’s delve into how this Health Law Attorney Email List – Health Law Attorneys Mailing Database by Lawyersdatalab.com can power effective marketing and foster growth in the health law sector.
The Health Law Attorney Email List is a specialized resource that holds the contact details of legal professionals dedicated to navigating the complexities of healthcare law. This meticulously curated database empowers law firms and lawyers marketing companies to initiate direct communication with experts in health law. Through targeted email campaigns, law firms can showcase their expertise, while lawyers marketing companies can share thought leadership content and engage with a receptive audience. This Health Law Attorney Email List not only fosters networking but also facilitates the exchange of legal insights and regulatory updates, making it an indispensable tool for anyone seeking to thrive in the intersection of law and healthcare.
Understanding the Health Law Attorney Email List
The Health Law Attorney Email List – Health Law Attorneys Mailing Database is a comprehensive compilation of email addresses and contact details of legal professionals who specialize in health law. This niche encompasses a wide array of legal matters related to the healthcare industry, such as regulatory compliance, medical malpractice, health insurance, and more. This Health Law Attorney Email List – Health Law Attorneys Mailing Database is meticulously curated to ensure accuracy and relevancy.
The Health Law Attorneys Mailing Database provides a comprehensive collection of contact information for legal professionals specializing in health law. This Health Law Attorneys Mailing Database offers an effective platform for law firms and lawyers marketing companies to connect with experts in the intricate field of healthcare law. With accurate and up-to-date email addresses, this mailing database allows for targeted outreach, enabling law firms to share their services and insights while lawyers marketing companies can engage potential clients effectively. This resource facilitates seamless communication and collaboration within the health law domain, serving as an invaluable asset for those looking to establish connections and expand their influence in the healthcare legal landscape.
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- Direct Outreach: With the Health Law Attorney Email List – Health Law Attorneys Mailing Database, law firms can initiate direct lines of communication with potential clients. Email marketing campaigns can provide valuable insights into legal trends, regulatory changes, and case studies, showcasing a firm’s expertise.
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Empowering Lawyers Marketing Companies
- Targeted Campaigns: Lawyers marketing companies can leverage the Health Law Attorneys Mailing Database to create highly targeted marketing campaigns. By focusing on a specific niche like health law, they can provide valuable resources to legal professionals seeking specialized insights.
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- Market Analysis: By analyzing the responses and engagement from email campaigns, lawyers marketing companies can gather valuable data on market trends, preferences, and pain points. This information can drive strategic decision-making.
In the ever-evolving landscape of health law, staying connected and informed is crucial for law firms and legal professionals. The Health Law Attorney Email List – Health Law Attorneys Mailing Database provides a strategic tool for effective outreach, communication, and collaboration. Whether it’s about staying updated on healthcare regulations, sharing legal insights, or expanding one’s network, this Health Law Attorney Email List – Health Law Attorneys Mailing Database is a valuable asset for those operating in the health law sector.
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Ready to tap into the potential of the Health Law Attorney Email List – Health Law Attorneys Mailing Database? Reach out to us at firstname.lastname@example.org to learn more about how this Health Law Attorney Email List – Health Law Attorneys Mailing Database can enhance your law firm marketing and lawyers marketing strategies. Unlock opportunities in the intersection of healthcare and law with accurate and targeted outreach.


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After two days of raging, uncontrollable fires, rain finally began to fall, leaving 3.3 miles of Chicago, Illinois in complete devastation. There were over 300 people dead, 100,000 people homeless and more than $200 million of destroyed properties. While this was a horrific tragedy for Chicago, it was also recognized as one of the most spectacular events of the 19th century. This fire was a prime milestone in the city’s history because it brought back significant reconstruction efforts, spurring considerable economic development and population growth.
Although the fire had damaged vast amounts of land, along with the spirits of the locals, some of Chicago’s physical infrastructure remained intact, like the transportation systems. Architects began laying the foundation for a modern city and were ready to create the world’s first skyscrapers. Within the next five years, the population of the city nearly doubled. By 1890, the city had a population reaching more than one million people, making it the second largest city in America.
Today, there are still three large buildings in the affected area that were able to be repaired. These buildings include the Chicago Water Tower, St. Michael’s Church, and the Chicago Avenue Pumping Station. The Chicago Fire Department training academy is located on the site of the O’Leary property where the Great Chicago Fire started. Finally, in 1997, the Chicago City Council passed a resolution that exonerated Catherine O’Leary of her (and her cow’s) accusation of starting the fire.

domain: geography


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in celebration of reaching 1000 plays on Soundcloud, SpockAndStep and GpXGD are hosting a remix contest for revelations! enter the contest to get a chance to get your Remix Featured in a Remix EP Featuring Remixes from Ry3, Vivid-music, False south, F-777 (hopefully. he said he would but that was over 3 months ago when the project started), and Revelations VIP! The deadline is November 15 at midnight, so better get started! good luck! and may the best producer win!
First place: the First place winner will be featured in the Remix EP, get a free download of the EP, as well as Discord nitro for one month, and a free download of the VR X Modestep – Spicy Riddim Drums sample pack as well as the barely alive sample pack.
Second place: a free download of the EP, and a free download of the VR X Modestep – Spicy Riddim Drums sample pack as well as the barely alive sample pack.
Third place: a free download of the EP
Submission details: when you submit your remix, use the tag #Revelationsremixcontest on YouTube and Soundcloud so SpockAndStep and GpXGD can judge your submission!
Key: A minor


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Keating, Perry offer sharp contrasts in 10th Congressional District race
All signs point to a bruising, brutal campaign into November. But already, Democrat William Keating and Republican Jeffrey Perry present 10th district voters distinct choices in a U.S. House race expected to draw national attention.
The candidates staked different stances during the primaries on most every hot button issue: health care, taxes, renewable energy, the war in Afghanistan and much more. As much as the addition of three independent candidates and character issues could sway the results, the race’s sharp distinctions may test how much the political landscape here has altered after decades of Democratic representation.
Fresh from his dominant defeat of former state Treasurer Joseph Malone, Perry returned to campaigning this week with his message of repealing the health care overhaul, resisting the offshore Cape Wind project and taking a hard line against illegal immigration.
“I think this district is ready for a conservative,” Perry said Thursday, between a Fox News interview and a campaign strategy session. “It’s going to be a very clear choice where voters get to say I prefer this vision or that vision.”
Democrats this week painted Perry, a four-term state representative from Sandwich, as an ultraconservative with character flaws. From the podium following a narrow victory over state Sen. Robert O’Leary, Keating immediately assailed Perry for his handling of a strip-search scandal involving a subordinate officer on Wareham’s police department in the early 1990s when he was a sergeant there.
Beyond such criticisms, Keating said he will draw distinctions on how he would fight for job creation and Social Security, an area where Keating has rigidly opposed raising the retirement age. He said he views Perry’s popularity among Tea Party supporters as an opportunity to make inroads with “traditional Republicans and independents.”
Perry warned that Keating is resorting to “gutter-style politics at his own peril,” saying voters are in no mood for attacks but instead want to hear solutions to the nation’s challenges.
“This is a job interview, and I’m standing before the people I want to hire me,” Perry said, pledging to run a positive campaign. “I’m not going to say, ‘Hire me because the guy waiting in the next room for an interview is a bad person.’”
Republican Party operatives, eager to win what they see as the state’s most vulnerable congressional seat, have signaled that they will be more confrontational than Perry, who has vowed to run a positive campaign. The National Republican Congressional Committee issued a statement accusing Keating of being a “radical Democrat” beholden to the party and a supporter of the “multibillion-dollar” Cape Wind project.
U.S. Rep. William Delahunt, who is not seeking re-election, opposed the project. The Quincy Democrat joined Keating and O’Leary – also a Cape Wind opponent – for three campaign stops this week in a show of party unity.
Todd Domke, a Republican strategist, said he was surprised by Perry’s fiery, take-back-our-government victory speech, saying it energized core supporters but may have been off-putting to moderates watching from their living rooms.
“Perry was sort of indicting the entire Democratic Party, saying at one point it has rejected the Constitution,” Domke said. “I imagine that even conservative Democrats listening were not too receptive to that.”
While registered Democrats outnumber Republicans 2 to 1 in the district, a majority of voters (55 percent) are not enrolled in a party. Even given anti-establishment sentiments, attacking Democrats is a risk given that a Democrat, first Gerry Studds, then William Delahunt, has held the seat since the 10th Congressional District took shape in 1983.
Still, this is also the same district in which Scott Brown, a moderate Republican, scored 60 percent of the vote. The fact is the 10th district – perhaps more than any other in Democrat-dominated Massachusetts – and this race may be wide open.
Turnout was slightly stronger in the Democratic primary.
Final results show Perry took nearly 10 percent more votes than Keating, with clear majorities in Plymouth, Barnstable, Falmouth, and other Cape towns. Keating was particularly strong in the north of the district, where he captured twice Perry’s votes in Weymouth and six times in Quincy.
“Both candidates clearly have a chance, and they present two very distinct choices,” said Paul Watanabe, a political science professor at the University of Massachusetts Boston. A Perry victory, he said, would reinforce the belief that Republican Scott Brown’s recent Senate victory was “not simply an aberration.”
John P. Kelly may be reached at email@example.com.
Uphill climb for three independents:
The three independents in the 10th Congressional District race include a 74-year-old former Quincy mayor and a state legislator-turned-lobbyist, both disaffected Democrats. Then there’s a self-described tradesman who, at 25, is just old enough to serve in the U.S. House of Representatives.
Many on the South Shore and Cape Cod have not yet heard of Maryanne Lewis, Joe van Nes or perhaps even former Quincy mayor James Sheets, who served six terms as mayor of the 10th Congressional District’s biggest city.
As they seek to boost their political profiles, political analysts said the odds are slim any of them will win. But collectively they could have an impact on the major party candidates, Republican Jeffrey Perry and Democrat William Keating.
Lewis, a Scituate attorney who served four terms as a state legislator and now is a lobbyist on Beacon Hill, said she plans to run a lean-and-mean campaign, tapping into a growing roster of volunteers to compensate for a fundraising disadvantage.
“I’m in this to win,” Lewis said in an interview at a former fire station in Weymouth that she converted into her campaign headquarters. She left the Democratic Party last winter, saying she has long been a centrist who never “toed the party line.”
Sheets announced he would run in June, saying the country was on the wrong track. His decision to leave the Democratic Party was sparked by passage of health care reform, which he said he felt is unfair to seniors.
Van Nes, of Martha’s Vineyard, stresses bringing home the troops, protecting the environment, and holding big business accountable. He decided to run after the Gulf of Mexico oil spill and said he has since raised $2,600.
While noting independents have higher hopes given distaste for Democrats and Republicans, van Nes admits having three in the race dilutes everyone’s chances.
“If I was the only independent, I’d have a better shot at winning,” he said.
READ MORE about this race.

domain: news


A nearly unbelievable video of a drone that delivers 12-packs of beer to ice fishers on a frozen lake turns out to be too good to be true. Beermaker Lakemaid created the video as a riff on Amazon's announcement on 60 Minutes last month, where the company showed a theoretical vision of a service that delivers small packages by air, autonomously. But where Amazon's vision of the future is just that — a vision — Lakemaid was well into the process of creating such a service for local beer delivery, though those plans have been put on ice by the Federal Aviation Administration.
"They think it's a great idea."
"They think it's a great idea, though they're telling me to stop," Lakemaid president Jack Supple told The Verge, adding that the FAA considers the project commercial and therefore off limits until those policies are reviewed and potentially revised next year.
Supple says the Amazon service was indeed the spark for the idea, which Lakemaid had planned to test out at Minnesota's Twin Pines Resort, situated on the western shore of Mille Lacs lake. The idea was to let those who were ice fishing put in orders without having to make their way back onto land.
"You know that people sitting in houses, just for the novelty of it, would order it," Supple says. "A frozen lake is the perfect venue."
But the reality of delivering beers by drone is not a simple operation. In the video you see a 12-pack take to the skies under the clutches of a six-propeller drone, though in reality it wasn't able to carry a full load. "It did deliver the box with something in it," Supple says. "[But] we had to keep taking bottles out to get it off the ground." An eight-propeller drone that's capable of lifting nearly 16 pounds would make short work of it though, and was going to be the delivery vehicle of choice for a real version of the service.
Human control still required
Another wrinkle: the video depicts the drone taking off and arriving to GPS coordinates seemingly on its own volition, something Supple also chalks up to video magic. The drone was actually being piloted by a human with a full visual of what was going on, though Supple believes the technical limitations of programming in the locations would be simple given how low ice fishing buildings are, and how flat the frozen lake is.
Lakemaid's video is not the first airborne alcohol delivery project to be shown off, nor is it likely to be the last. Earlier this month champagne vendor Plus de Bulles showed a video of champagne being sent to a bar near the top of the Verbier resort in Switzerland, though it required the recipient to take it off the drone with a pair of pliers. During an earnings call last month, FedEx's chief executive also noted that its current drone delivery research was currently capable of carrying "about" four cans of beer, with an operational time of roughly eight minutes.
Despite running up against the legal roadblock, and some rather obvious implications of running into other legal trouble complying with drinking age requirements, Supple says he's not giving up hope on the service, nor is the FAA. "They've told me ‘you'll be ready.'"


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After the U.S. dollar hit a new low last Friday, Patricia Pérez, president of the Export Manufacturing Association (Asexma), warned of the serious threat posed to Chile's exporters and manufacturers.
The low of CLP$520.5, a mark not seen since May last year, is nowhere near "the 580 to 600 pesos per US dollar needed for exporters to have reasonable profits," said Pérez. "The big companies have the resources to withstand prolonged lows, but medium-sized exporters face the difficult decision of either closing factories or markets." The export, fruit export and manufacturing sectors have all called on the government to loosen regulations on the private pension funds (AFPs) to allow them greater leeway to invest their dollars abroad (ST Apr. 19). The AFP invests millions of dollars each year, and foreign investment of their U.S. dollars would increase the value of dollars remaining within the country. By Mike Hager The Santiago Times


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Things Which Shows That Your Family Member Should Visit an Autism Expert Today
Autism can be described as the disorder which is characterized by low communication skills and social challenges. You will see that autism effect among the children in the world today. Most of the people who are being affected by the autism Blue Sprig Autism problem are most in the boys than in the girls. Most of the children Blue Sprig Autism who are affected experience thus effect at the age before they go through the school system. The awareness, more resources, and the many autism experts have led to the experts in the coming up with many autism stats. You will get many benefits of visiting autism experts in the world today. This article will take you through some of the important signs your family member should visit an autism specialist today.
The first sign should enable you to take your family member to the autism expert at an early stage. The autism effects Blue Sprig Autism usually bring different signs at the early Blue Sprig Autism stages of a child. Therefore when the family member is passed through the spectrum, then the signs can be detected at different degrees. The children can have poor social interaction at their early ages. There are also who will have a various sign which may raise the alarm for further testing. The intellectual disabilities, when detected at early stages, can raise questions in the life of a child.
The second sigh why your family member should visit an autism expert is when they have social interaction challenges. It is clear that most of the people with autism conditions usually have difficulties in the social interactions. Some of the signs of poor social interaction include difficulties in starting a conversation. You will also find those who find it hard to accept changes. These signs are common during the growth of a child. This is the reason why you should be aware of the autism signs.
Autism expert can ease your worry, and this is the reason why your family member should visit an autism expert. You family member who is on autism expert spectrum will only reduce your worries when they visit the autism specialist. You will get care and support from them. This will help your family member to get a happy life again. The autism spectrum will tell everything on the condition.
In conclusion, this article has explained some of the essential signs of why your loved ones need to visit an autism specialist.


Launched at home in Japan back in 2012 before getting here in international markets later in 2013, the current Corolla got a mild update last year that needs to keep it fresh until the next generation. Spotted early in the testing phase, the all-new model was carrying several kinds of camouflage to conceal the changes that remain in tow as far as the exterior design is worried.
Toyota engineers are out testing what’s destined to be the 12th generation of the Corolla. The engineers are still at the test mule phase, suggesting the majority of what you see here will be altered by the time the car lastly debuts.
That debut is anticipated to take place in late 2018 or early the following year. That suggests we’ll likely see the brand-new Corolla presented for the 2019 model year. Toyota is known to also be working on the hatchback variation of the new Corolla, which if presented to the United States will change the present Corolla iM.
2019 Toyota Corolla Design
The brand-new model will be a true redesign. Its platform will be Toyota’s TNGA modular design which currently features in the current versions the Prius and Camry along with the new C-HR. The platform enables a low center of mass and increased body rigidity and must see the brand-new Corolla handle better than previous generations.
2019 Toyota Corolla Engine
It’s prematurely to talk powertrains however expec a series of inline-4s and maybe a hybrid choice. Toyota has actually announced new 8- and 10-speed automated transmissions that will be coming to change a variety of 6-speed and CVT units it currently uses, though it’s not clear if these will make it into the brand-new Corolla.
The report mill indicates Toyota will install a BMW engine below the hood, as part of a tie-up in between the 2 car manufacturers signed some years earlier. If the reports will pan out, the 2019 Corolla will follow the BMW-powered Verso MPV and the Avensis midsize sedan and wagon.


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High school football entered week 7 across the state. Our broadcast coverage featured the Sheldon Orabs playing host to #2 Boyden-Hull/Rock Valley.
The Coach goes perfect for the week to extend his lead and pulls away from everyone.
Iowa State coach Matt Campbell says his team is making progress despite a slow start to the season. The Cyclones take a 1-3 record on the road to Oklahoma State.
UNI coach Mark Farley hopes the home fans can make a difference when the Panthers host FCS top ranked North Dakota State. UNI opened the Missouri Valley race with a 33-0 win at Indiana State.
Floyd of Rosedale will be on the line when Iowa visits Minnesota. It will be the 112th meeting in the series and matches teams with identical 3-1 records.
Rivals collide in the Great Plains Conference this weekend in Orange City when Northwestern hosts Dordt.


A majority of the most challenged books of 2022 were written by or about LGBTQ+ people or people of color, a new report from the American Library Association found.
The association released its annual list of the top 10 most challenged books Monday, with Maia Kobabe’s graphic memoir, “Gender Queer,” being the most targeted for the second year in a row.
In 2022, the association tracked 1,269 challenges, which it defines as a “formal, written complaint filed with a library or school requesting that materials be removed because of content or appropriateness.”
The challenges in 2022 targeted over 2,571 unique titles, a significant increase from the 1,858 targeted in 2021.
In fact, 2022 saw the “highest number of censorship reports since the association began compiling data about library censorship more than 20 years ago,” the report reads.
The “top 10” list is a little different than in years past; instead of 10, there are 13 most challenged books because several books tied for being the most targeted.
Here are the top 13 most challenged books of 2022, per the American Library Association.
1. “Gender Queer,” by Maia Kobabe.
2. “All Boys Aren’t Blue,” by George M. Johnson.
3. “The Bluest Eye,” by Toni Morrison.
4. “Flamer,” by Mike Curato.
5. (Tie) “Looking for Alaska,” by John Green.
5. (Tie) “The Perks of Being a Wallflower,” by Stephen Chbosky.
7. “Lawn Boy,” by Jonathan Evison.
8. “The Absolutely True Diary of a Part-Time Indian,” by Sherman Alexie.
9. “Out of Darkness,” by Ashley Hope Perez.
10. (tie) “A Court of Mist and Fury,” by Sarah J. Maas.
10. (tie) “Crank,” by Ellen Hopkins.
10. (tie) “Me and Earl and the Dying Girl,” by Jesse Andrews.
10. (tie) “This Book is Gay,” by Juno Dawson.
“By releasing the list of Top 10 Most Challenged Books each year, ALA recognizes all of the brave authors whose work challenges readers with stories that disrupt the status quo and offer fresh perspectives on tough issues,” association President Lessa Kanani’opua Pelayo-Lozada stated.
“The list also illustrates how frequently stories by or about LGBTQ+ persons, people of color, and lived experiences are being targeted by censors. Closing our eyes to the reality portrayed in these stories will not make life’s challenges disappear. Books give us courage and help us understand each other.”


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British Prime Minister Boris Johnson’s special envoy met Taliban leaders in Afghanistan to discuss the humanitarian crisis and ways to prevent the country from becoming an incubator for militants.
Simon Gass, Johnson’s high representative for Afghanistan, met Taliban leaders including Amir Khan Muttaqi, Mullah Abdul Ghani Baradar and Abdul Salam Hanafi, the Foreign Office said.
They “discussed how the UK could help Afghanistan to address the humanitarian crisis, the importance of preventing the country from becoming an incubator for terrorism, and the need for continued safe passage for those who want to leave the country,” the Foreign Office said.
“They also raised the treatment of minorities and the rights of women and girls.”
Gass was accompanied by Chargé d’Affaires of the UK Mission to Afghanistan in Doha.
Abdul Qahar Balkhi, the Taliban’s foreign ministry spokesperson, said the meeting “focused on detailed discussions about reviving diplomatic relations between both countries”.
Afghanistan’s opium production: prices skyrocket after Taliban takeover
He added that Afghanistan’s foreign minister wanted Britain to “begin a new chapter of constructive relations”.
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Aldar Properties saw its second quarter profits more than double to Dh1.2bn compared to last year.
Aldar's Q2 profits double
ABU DHABI // Aldar Properties saw its second quarter profits more than double to Dh1.2 billion (US$326.7 million) compared to the same quarter last year, officials said yesterday. The largest developer in Abu Dhabi, with some 72,000 employees and Dh14.5bn worth of projects under development, is maturing as a company and starting to see a steady stream of income and business, analysts said.
"This quarter and indeed the first six months of the year reflect that its business is beginning to take shape, its income streams are beginning to contribute in a clearer fashion," said Sana Kapadia, an analyst at EFG-Hermes. She said that while revenues beat expectations, costs were higher than expected. Analysts' forecasts for Aldar's second quarter profit ranged from Dh801.83m to Dh1.5bn, according to Reuters, which conducted a survey last month.
Shafqat Malik, the chief financial officer of Aldar, said the company had benefited from land sales in particular. Of the Dh1.2bn of profit, Dh773m, or 64 per cent, came from the sale of plots of land. Aldar still has a land bank of 38 million square metres, a resource that is likely to fuel earnings for years to come. Mr Malik said the second quarter saw a continuation of a strategy the company started in the fourth quarter of last year, when it began selling apartments and land.
Aldar's profit for the first half of the year was Dh2.6bn, an increase of 168 per cent from Dh970m in the first half of last year. The amount of projects under development rose by 74 per cent to Dh14.5bn in the first half, compared to Dh8.3bn in the same half last year. One of the largest projects the company announced in the second quarter was Motor World - a Dh11bn, 3.5 million square metre development that will bring all the major car businesses of the capital under one roof. Aldar also announced Al Ruwais, a 30,000 square metre mall near the Saudi Arabian border.
Mr Malik said the company also had a successful period for raising financing, bringing in a total of Dh9.52bn in the first six months. In April, Aldar announced a Dh2.2bn ijara, or sharia-compliant home financing concept, and last month it issued a Dh3.75bn sukuk, an Islamic bond, which was well subscribed. Since it was formed in 2004, Aldar has delivered several individual buildings, including Al Mamoura on Muroor Rd, but it is expected to begin finishing part of its major projects next year. These projects include components of Yas Island and Raha Beach. Aldar is also building two small island projects off the shore of Abu Dhabi Island - Coconut Island and Al Gurm - as well as a new Central Market and a major part of the Shahama-Saadiyat motorway that will connect Sheikh Zayed Rd directly with Abu Dhabi Island.
Aldar's share price lost Dh0.15 in trading yesterday, closing at Dh12.25. The price has gained about 21 per cent in the past six months. @Email:firstname.lastname@example.org


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We have to remember that secular scientists, God help them, consinstently state that earth has been around for “millions” of years, even though a host of evidence not only disproves that theory, it is becoming laughable and almost shocking to see them continue to spew their rhetoric. However, that being said, this articles to me pertains to a hybrid. I might be skeptical. But God clearly tells us he does not mix species. But scientists with “god complexes” do.
Ye shall keep my statutes. Thou shalt not let thy cattle gender with a diverse kind: thou shalt not sow thy field with mingled seed: neither shall a garment mingled of linen and woollen come upon thee – Leviticus 19:19 (KJV).
This article serves to point out only the fact that this creature was discovered and since it is one of its kind (at least known at this time), I reject that that this conclusively proves that this animal is a species.. But that is my opinion only.
New species of marine reptile — a cross between a giant dolphin and crocodile — identified from Scottish fossils
A team of researchers has identified a new species of marine reptile that would have been at the top of the food chain in the Jurassic era from fossil remains in Scotland.
Scientists from the University of Edinburgh say the creature looked like a cross between a giant dolphin and crocodile. It lived in the early to middle Jurassic era for about 170 million years.
“This is a totally new species,” said Stephen Brusatte, a doctor of vertebrate palaeontology at the University of Edinburgh. “It was a giant creature that would have been about the size of a motorboat or about four-metres long.”
The creature, dubbed “Dearcmhara shawcrossi,” lived for about 170 million years during the mid-Jurassic era. [laughable really, come on lets stop that nonsense of lying millions of years, hahaha]
In its time in the depths, it would have eaten fish and other reptiles, Brusatte said.
“It technically isn’t a dinosaur, because dinosaurs only lived on land, but could be considered its cousin,” Brusatte said.
“It would have been at the top of the food chain during its time,” he added. “It would have filled the role of sharks or that of killer whales today.”
The researched dubbed the new species Dearcmhara, a Scottish Gaelic term meaning marine lizard, and shawcrossi, after the fossil hunter who discovered the bones.
The bones were found by Bryan Shawcross in 1959 in Bearreraig Bay on the Isle of Skye. Shawcross kept the bones in his own private collection for decades before donating them to National Museums Scotland.
Brusatte hopes that naming the new species after the person who discovered the fossils will welcome other amateur collectors to share their discoveries with academics.
“What has changed in the last decade is that private and amateur collectors and researchers are pooling their resources together, leading to new discoveries,” Brusatte said. They would happily name any fossils in the future that are donated to research after the amateur collectors that find them.
“Scotland is one of the best places in the world for finding fossils,” claimed Brusatte.
The study on the Dearcmhara shawcrossi was published in the Scottish Journal of Geology.
Source: National Post


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Anyhow, as Salamanderanagram has shown - you are incorrect in your assertions.
Another simple test is to modify the structure in the image you posted as follows:
Remove the A to E perm, and connect the switch output directly to the + module.
Attach the output of the add to an Expon(F), then connect that to the F input of the sine osc. Remove all connections to the P input.
Notice that the sound is identical, but you have a cleaner structure - no more daft audio rate event stream.
Now, to avoid serious injury, use a spork for the decapitation.

domain: design


text:
Record producers, obtain a release from an artist in connection with promotion of a record with this Musical Artist Release Form for Use of Likeness.
- The artist grants the record company and related parties (distributors, advertisers, affiliates, etc) the right to use the image and likeness of the artist for purposes of advertising and promoting recordings containing a performance by the artist as a musician or vocalist.
- The artist agrees not to make any claim against the record company for any reason, including invasion of privacy.
- The file includes a section to be completed if the artist is a minor (under 18 years of age).
- This is a reusable release form. Buy, download, use it as often as you need to.
This Musical Artist Release for Use of Likeness
template is provided in MS Word format, and is fully editable.


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Gupta may still appeal to the US Supreme Court. He has also been fined millions of dollars.
Gupta began his prison sentence after fighting a protracted legal battle to clear his name in one of the biggest insider trading schemes in US history.
The gulf between pvt and public sector banks has been widening on various parameters — growth, bad loans, profitability, service standards etc.
Preet Bharara nailed Mathew Martoma, who worked for hedge-fund billionaire Steven Cohen, getting him 9 years in prison for insider-trading.
The verdict came as a blow to Bharara and his team of federal prosecutors who have not lost a case in the years-long crackdown on insider trading on Wall Street.
"The overall impression that we have got from our speakers, corporates and clients is that they believe that growth is definitely on a rebound."
Prosecutors accused Martoma of making illegal trades in pharmaceutical stocks based on tips about a clinical trial for an Alzheimer's drug.
The number of cases has increased, with 57 per cent of the sentences imposed in the past five years. The last three years alone have seen two record sentences.

domain: finance


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Despite our best intentions, sometimes we’re just too damn lazy to get busy in the kitchen. When we’ve had a long, stressful day at work and had a frustratingly long commute home, it’s too tempting to fire up Just Eat and have someone else do the cooking. What we need is healthy food, ready to go so that we don’t even have to think about it. Enter: meal prepping.
Preparing your meals for the week in one go is a great way of helping you reach your weight loss goals. The benefits of doing so are pretty obvious – if you’ve got your food ready and waiting for you, it’s much less likely that you’ll opt to eat something unhealthy because you’re too tired to make something. Here are some easy ways to make meal prep work for you…
You don’t have to go all out
Meal prepping is not just for Instagram foodies who line up seemingly endless rows of plastic boxes for a good photo-op: you can prep as much or as little as you like. Struggle to get up in the morning? Prep some breakfasts in advance. Keep finding yourself staring at Boots meal deal options on your lunch break? Prep some lunches you can grab on your way out of the door in the morning. Got a busy week coming up? Prep everything! It’s all about making your life easier.
Make stuff you’ll actually eat
It’s all well and good making a week’s worth of meals in one go but there’s no point if it gets to Thursday dinner time and you don’t want to eat what you’ve made, no matter how good your intentions were earlier on in the week. Not really into trendy health foods? Then don’t make a massive vat of quinoa that you’ll never want to have. You can still make exciting meals in advance – want to have burgers one night? Prepare the patties ahead of time, store in the fridge and whack them on the grill for a few minutes when you need them.
You don’t have to meal prep everything
If you’re thinking that a week of meals prepared in advance means a week of eating cold food straight from plastic tubs, it’s worth bearing in mind that it doesn’t have to be like that. Instead, just lighten the load by getting things ready for the week. You could chop a load of salad ingredients so you can make a quick salad for lunch, grill some chicken breasts and whip up a tomato sauce so you can have a complete meal in the time it takes to cook some pasta. These little things will be a major help when you come home from work and are tempted to call up your old friend Papa John.
Make your ingredients multitask
When you’re shopping for ingredients for the week, stock up on kitchen staples that can work overtime. For example, there are loads of things you can do with a pack of mince: bolognese, chilli, lasagne – they’re all more or less the same, but different enough to not feel like you’re eating the same thing every day. You’ll soon master the art of making all three at once.
Plan out your meal prep session first
We know it’s way more fun to wander around Asda throwing anything that looks tasty in your trolley but that doesn’t really work when you want to lose weight. You need to sit down and figure out exactly what you’re going to eat during the week and then make a shopping list based on that to make sure you’ve got everything you need. This is the best way of making sure your meal prepping is simple, effective and as easy to do as possible. As our English teacher used to say, fail to prepare and prepare to fail.
Get some good storage
If you’re going to be storing food in tubs, it’ll make your life a lot easier if they’re decent. We’re well aware that getting excited about good quality tupperware is a sign of impending middle-age, but you don’t want to be worrying about them leaking, especially if you’re taking your food to work. These food containers, which are BPA-free, come highly recommended and they’re handily split into compartments to keep food separate until you’re ready to mix them.
Save time with gadgets
It’s probably not the best idea to splash the cash on shiny new kitchen gadgets if you know you’re probably only going to use them once before resigning them to the back of the cupboard like every other must-have gadget (popcorn maker, anyone?) but if you’re committed to meal prepping you could really save some time with a kitchen buddy – a food processor will cut down on tedious chopping and grating time and one of those dinky little personal blenders will make breakfast smoothies a breeze (speaking of – keep your eyes peeled for a competition to win one on the blog next week).
Cut down on food waste
If you’re going to be cooking from scratch, make the most of your freezer by buying pre-chopped frozen veggies to cut down on prep time (and tears, if you’re using frozen onions) and waste, as you’ll only use what you need from the bag before putting it back. Liberate your fridge’s veggie drawer from sad, wilted spinach and what you think was once a courgette and fill the freezer – chopped onions, peppers, courgette and broccoli are all excellent cooked from frozen, and now you can even buy frozen avocado halves from Tesco (for £3! Bargain) and Iceland, which are perfect for defrosting and mashing on a bagel or toast for a quick breakfast.
Make one day a meal prep day
Meal prepping can seem like a daunting task if you’re trying to do it for the entire week, but really it’s not too bad if you get it over and done with in one day. We suggest you do it all on a Sunday so that you’re ready for the week ahead. Set yourself up in the kitchen with some good music, a fully stocked up fridge and your meal plan and get to work. Top tip: if you wash up as you go along it’ll make looking at the kitchen at the end of the day a little less soul-destroying.
Are you a fan of meal prepping? Got any tips you’d like to share? Let us know over on the forum.

domain: food


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Holden / Caprice / V8 sedan
HOLDEN, Ford - and now Chrysler - are still holding out as purveyors of genuine American V8 muscle.
Ford (via multi-camshaft breathing, four-valve cylinder-heads) and Chrysler (via the 300C's Multi-Displacement System, that cuts out four cylinders when not needed) approach the fuel consumption issue with technology, while Holden has just given us a new, enlarged version of its all-alloy V8 that provides the useful mid-range torque its predecessor lacked via a bigger capacity and a few refinements.
It's a tangible improvement over the already quite meaty Gen III, improving the on-road experience, but the big thing is that it now comes with the electronic stability control and more refined ABS that were missing in previous Holden V8s.
Model release dates: January 2006 - August 2006
GoAuto’s New Car Buying Service
Buy a New Holden Caprice today!
The latest Caprice tested here is unchanged from the WL series launched in August 2004 - apart from the new Gen IV 6.0-litre V8, more refined ABS and the fitment of stability control.
The Gen IV replaces the 2004 car's 250kW/470Nm 5.7-litre Gen III V8, which fails to meet tighter new emissions regulations from 2006.
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Utah's gymnastics team, which finished fifth in 2012, was picked to finish fifth again in 2013 in the coaches' preseason poll.
The Utes received one first-place vote and a total of 568 points.
Defending champion Alabama was picked first with 689 points followed by UCLA (645), Florida (644) and Oklahoma (622).
Stanford, Nebraska, LSU, Oregon State and Michigan round out the Top 10.
Utah opens its season at UCLA on Jan. 12.
The home opener is Jan. 12 against No. 9 Oregon State, West Virginia and SUU.
Other Pac-12 teams joining Utah, Oregon State, UCLA and Stanford in the rankings were No. 17 Washington and No. 19 Denver.
Utah will host a sneak preview for fans Friday in the Huntsman Center at 7 p.m.
- Lya Wodraska
|1.||University of Utah study: Lizard lungs work like birds’, and nobody knows why|
|2.||Mormon church traces black priesthood ban to Brigham Young|
|3.||NSA head says metadata program key tool against terrorism|
|4.||Friends rally to help former Utah football star Bronzell Miller, given two weeks to live|
|5.||Few searchers remain in quest for 5 missing in central Idaho plane crash|
|6.||‘A Snow White Christmas’ brings new family tradition to Salt Lake City, panto style|
|7.||Mitt Romney documentary a standout amid Sundance’s stars|
|8.||Restaurant review: Menu misses at The Annex in Sugar House|
|9.||All I want for Christmas is a new Christmas song|
|10.||University of Utah students protest over diversity concerns|


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In a community-led restoration initiative, a coastal village in Central Kalimantan has been ramping up its effort to plant trees on 50 hectares of land. The approach gives ownership to the community, contributes to the local economy, and serves to restore degraded land.
The land where Sabuai Village is located is categorized as degraded areas according to the map of critical land issued by the Ministry of Environment and Forestry (KLHK). We support this village in implementing community-based restoration, considering the commitment of the community and village government to protecting and maintaining the forest.
The restoration in Sabuai village is a carefully planned and organized activity. The planning and establishment of the restoration team began in early 2020. The regreening efforts have been given a broad welcome by the community, many of whom were involved in the discussion of plant species selection, participated in searching for the seedlings of native plants, and went to the field to plant the trees on vacant land by themselves.
As of now, 38 hectares of land have been restored. And 12 hectares of land are left to be planted with sugar palms and native hardwood trees called kanenasihan.
However, some spots of the restoration site are flooded during this rainy season. The community is waiting for the land to get dry first.
“Once the situation gets better, we’re going to plant the rest and complete this project soon,” said Tohhari, the head of the restoration team.
The reforestation program, supported by Kaleka and Unilever, brings various direct benefits to the community, including an additional income stream, especially as many local farmers struggle to adapt to more frequent climate disasters that affect their harvests. Apart from oil palm, farmers also cultivate coconuts, horticultural crops, and woody plants.
In the long-term, he hopes that the locals can enjoy the benefits of planting the trees by selling high-value crops, like durian and longan.
Tohhari, who is also a village head, felt a sense of responsibility to support his community in Sabuai village in every way possible.
The 50-hectare restoration program is the first time his village has carried out the tree-planting effort. A restoration team was formed to organize the activities and make sure of the lasting impacts of these activities, including monitoring the growth of the trees and getting rid of weeds in the restoration area.
Moreover, the team has ensured that the trees are planted only on public land, not on privately owned land. This aims to minimize the risk of conflicts.
“When the trees have matured, everyone can harvest the fruits. Our restoration team will design community harvest patterns later,” Tohhari said.
Soon, they’re going to take on a new project of mangrove restoration as an attempt to restore their coastal areas. At a time when climate change is increasingly threatening shoreline communities, such restoration efforts are expected to strengthen the resilience to climate change and reduce the risks of natural disasters, such as forest fires and floods.
“We just faced a coastal flood in late 2021,” Tohhari said, adding that high tides and strong winds led the seawater to reach the housing areas located around 700 meters away from the coastline. “This was the first time in decades.”
One effective way to realize climate solutions is by entrusting the activities to local communities. This community-led restoration initiative allows the locals to understand the benefits of planting trees, carry out the activities, and reap the benefits of their hard work.


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YIELD: Makes 1 loaf
In a bowl beat the eggs until they are frothy and stir in the olives and 2 tablespoons of the oil. Into the bowl sift together the flour, the sugar, the baking powder, and the salt, add the milk, and stir the mixture until it is just combined. Brush an 8 1/2- by 4 1/2-inch loaf pan with the additional oil, transfer the batter to the pan, and bake the bread in the middle of a preheated 350°F. oven for 1 hour, or until a tester comes out clean. Let the bread cool in the pan for 10 minutes and turn it out onto a rack.


I am at 13K on my Titanium. As far as hill assit .. I have an "automatic" .. and it works. If you are on a hill and stop by putting your foot on the brake, when you release your foot off the brake you have about 3-5 seconds of hill assist. That is more than enough time to get your foot from the brake to the gas. If you are not getting that amount of time there is a problem. I love the feature since a dual clutch transmission is not a real automatic and will have roll back.
The stutter went away after 500 miles. The transmission works the way it was designed up to yesterday. Yesterday it was sluggish up-shifting. I took it to my dealer this morning. There are a bunch of TSB that they are going to perform on it today. I will keep every one informed on how that goes.
As far as the MyFordTouch, if you have not had your dealer update it yet, it is something you can do yourself. All you need to do is download the files on to a 1 gig thumb drive and than plug it into the USB in the car. It takes about 45 minutes to upload into the car. the down load on to the thumb drive depends on your internet speed and some other factors.
The 2012 Focus is one of the most advanced cars out there ... and yes .. being the first one out of the gate there will be some bugs.
When I am driving the car it just feels like a car that costs a lot more. Ford is working feverishly to solve the problems. They worked so hard to climb to the top of JD Power and Consumer Reports .. and now they have tumbled.
Alan Mulally has taken the fall very seriously. In an interview he took responsibility but his comment went on to say ... I will paraphrase "The quality of the Ford products are right up there with the best with the exception of the MyFordTouch and the dual clutch transmissions. We have two items to fix. This is far better than having mechanical and engine failures across the board. With two problems Ford can focus on these two items and get back to being at the top again."
I respect everything Mulally has done. With risk comes reward. Some times with risk comes failure, but if you learn from mistakes you will lead the pack and not be a follower.


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Experiences of Rajasthan - Transport
Air Links :
Indian Airlines and private air taxi operators - offer regular fights to New Delhi and Bombay from Rajasthan. In addition to Jaipur, Jodhpur and Udaipur are also air linked. Jaisalmer and Kota are likely to be air linked soon. Jaipur, Udaipur, Bikaner, Kota are Jaisalmer are included in the list of cities open to private air taxi operations.
The State has an air cargo complex at Jaipur. A similar facility has been developed at Jodhpur and Udaipur. Jaipur airport is expected to be developed as an international airport by the end of the decade.
Rail Links :
All major towns and most district headquarters in the State have rail links for both passenger and goods traffic.
At present, most destinations in the State are served by metre gauge railway, while the majority of the rail network in North and West India is broad gauge.
However a major track renewal programme to convert existing metre gauge routes to broad-gauge is under implementation. This would take the BG network in Rajasthan upto 55% as against the present 21.5%. Large part of the broad-gauge conversion work is now complete. Jaipur now had direct broad-gauge connection to Delhi through Rewari. Jaipur and Sawai-Madhopur have already been linked on Broad-Gauge under this programme thereby connecting it to Bombay through Kota. Track renewal from Phulera-Degana -Merta Road -Jodhpur is also complete. Similarly the track from Kolayat-Lalgarh-Bikaner-Merta is also now on broad-gauge. Alwar-Mathura route is also converted.
On completion of the work, Jaisalmer would also be brought on the broad-gauge network. The Marwar-Ahmedabad route will also be broad-gauge thus bringing Jaipur on the prestigious Delhi-Ahmedabad route.
The total Road Mileage in Rajasthan is 2846 km of National Highway and around 58680 km of State Roads and Rural links roads. Four national highway i.e. No.8 (Delhi-Ahmedabad), No. 11 (Agra-Bikaner) No.15 (Bhatinda-Kandla) and No.12 (Jaipur-Bhopal) pass through Rajasthan. Roads provide the most convenient mode of travel between Delhi and various industrial locations in eastern Rajasthan, most of which are 1-3 hours of comfortable road journey from Delhi.
All district and subdivisional towns have direct bus service to Jaipur. Jaipur and other major towns are connected to each other and to Delhi and Ahmedabad (largest city in neighbouring Gujarat) by deluxe bus services.
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The draft conference programme for Global Addiction 2015 in Belgrade will be available shortly
Topics to be covered include all subjects relevant to the understanding and treatment of addictions. For more detail on these subjects please review the image below. You can click to enlarge it.
The following list outlines the main topics that will be covered by the invited Keynote Speakers:
1. Access to Treatment - policy, detox & maintenance
2. New psychoactive substances
3. Comorbidities – eg. HIV & Hep C
5. Pain management, legal medications and addictions
6. Medical use of cannabis
7. Opioids Update
9. Prisons & Criminality
10. Healthy work place
11. Gender issues
12. Self help
13. Drug legislation in SEE
14. Policy, Society, Trafficking and Governmental issues
The so-called 'novel’ addictions such as video game addictions, sex addiction, designer/club drugs, prescription drug addictions (eg. Opioid pain killers, sleeping pills, NSAIDS etc), gambling, cosmetic addictions (eg. amphetamine for weight loss, cosmetic surgery etc) continue to be of importance… and submissions on these topics will be well regarded for the conference, however as ever, any topic relating to addiction will be reviewed and can be included in the programme.
The committee is currently considering and accepting submissions on all these topics and creating the programme for the three day conference. To join the committee please email firstname.lastname@example.org with a short summary of your area of interest.


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About this recipe:A great healthy drink made with a juicer. Perfect for detoxing after the Christmas holidays or whenever you have overdone it. Adjust fruit and veggie amounts to suit your personal taste. More apple equals a sweeter drink. Store any extra in the fridge for up to one day. Shake before drinking.
2 green apples, halved
4 celery sticks
6 kale leaves
1/2 lemon, peeled
1 (2cm) piece fresh ginger
Add to shopping list
Turn this recipe into a shopping list you can print, email, view on your mobile or shop online. It's free! Powered by Whisk.com
Method Prep:10min › Ready in:10min
Process apples, celery, cucumber, kale, lemon and ginger through a juicer.


While many running backs have already been ruled out for Week 3, many wide receivers are listed as questionable, which adds to the challenge facing some fantasy owners when it comes to determining their starting lineups. Week 2 was rough on wide receivers, and many of these players missed practice time this week. Curtis Samuel has already been ruled out, same for Doug Baldwin. However, Baldwin should be returning soon, so if he is on the waiver wire for some reason, don’t hesitate to add him.
Source: Athlon Sports & Life –
Read the full article here: NFL Injury Report: Larry Fitzgerald, Alshon Jeffery, Marquise Goodwin, Chris Godwin for Week 3


The US military budget is $824.6 billion. US military spending is larger than the next nine countries combined. The 2018 year budget of the Russian Defense Ministry will total $46 bn. Despite the huge difference in expenditure, the military potentials of the two great powers are compared without offering indisputable conclusions. This is a very interesting phenomenon and many people wonder how it is possible.
Launching a program of developing a new weapon system is a great responsibility – success is never guaranteed and there are always snags on the way. It’s an open secret that Russia’s R-30 Bulava submarine launched ballistic missile (SLBM) has been plagued with problems. It was not design but rather production quality. Thorough study has been done to overcome the difficulties. It’s all over now as the recent tests show and the missile with enhanced ability to evade enemy anti-ballistic missile (ABM) defenses has entered service.
Another major program – the PAK FA, now renamed the Su-57 fighter – had not run smoothly. A lot of effort was applied to develop a new power plant. In early December, 2017, the aircraft was successfully flight-tested with a new engine.
The T-14 Armata new generation tank, which is able to fire an anti-tank missile at targets more than seven miles away, is to enter service in 2020.
Russia's newest nuclear ballistic missile submarine (SSBN) the Knyaz Vladimir (Prince Vladimir) was officially launched last November.
It’s always more difficult than expected but the plans go through. There could be delays and expenditure may go up but what really matters is that no major Russian armament program has been shelved or abandoned.
The new US National Security Strategy emphasizes hypersonic weapons, laser and beam weapons, electromagnetic railguns, counter-space weapons, and artificial intelligence-directed robots to ensure America superiority in the 21st century leaving behind Russia and China.
The magnitude of US weapons programs takes breath away. The world is watching to be often frustrated by the news that much-hyped programs are suspended or to be revised to do away with shortcomings and staggering costs. Roughly, $85, 8 billion have been spent in the recent ten years on the programs that have never come to fruition. For instance, the suspension of the decade-long, electromagnetic railgun (EMRG) program in favor of a cheaper alternative was quite a shock.
It’s an open secret the US, Russia, China, Israel and some other countries are working on the weapons based on new physical principles. But only the US has is the only one to have a ready platform to install such a weapon on. Initially USS Zumwalt (DDG-1000) was to carry 80 Tomahawk cruise missiles and a railgun. Instead it will carry an ordinary gun with a range of 148 km. The range is great but…the cost of one shot is $2 million. It’s comparable with the cost of a Tomahawk missile, which can travel much farther carrying a much heavier payload. And the result? The US Navy has received a $4bn ship with the capability of 1,5bn Arleigh Burke destroyer!
F-35 Lightning II – the most advanced strike aircraft – was to become the backbone of Air Force and Navy fighter fleet. 265 aircraft has been produced since 2006. The cost is $100bn in nearly 25 years – staggering enough to make President Trump ask questions. One plane costs $100 million. At that the aircraft still has a long way to go before it will be operational, probably no earlier than 2021. In October, the Israeli Air Force used F-35s to strike Syrian army’s positions near the city of Baalbek. One of the planes was reported to be damaged by the obsolete S-200 air defense system in service since 1967!
The Boeing YAL-1 Airborne Laser Testbed (formerly Airborne Laser) weapons system was a megawatt-class chemical oxygen iodine laser (COIL) mounted inside a modified Boeing 747-400F. It had been expected that the US would be able to knock out enemy’s ballistic missiles. In 2010, the system hit two missiles during a test in California. But the problems proved to be insurmountable. The cost of one-hour flight was $92 million. The operational range was over 80 km to make an aircraft enter the enemy’s air space becoming vulnerable to air defenses. As a result, the program was scrapped in 2011 and the aircraft was taken out of service in 2014. The estimated cost of the program running from 1996 to 2011 was $92 – the money gone down the drain.
Future Combat Systems (FCS) was the Army’s principal modernization program in the period from 2003 to early 2009 claimed to be "most ambitious and far-reaching modernization" program since World War II.” The goal was to create new brigades equipped with new manned and unmanned vehicles linked by an unprecedented fast and flexible battlefield network. It was curtailed in 2009 to be cancelled in 2011. The only result was the XM1216 lightweight, man portable Small Unmanned Ground Vehicle (SUGV) that can be used in military operations conducted in urban environments, tunnels, culverts and caves. Some developments were used for the implementation of the Brigade Combat Team Modernization concept. The cost of the failed program was $18, 1 bn.
USS Gerald Ford, the first-in-class aircraft carrier, was delivered to Navy after 15 months of delays. The cost-$14 bn.
There is a reason to say the sky-high costs don’t result in the implementation of programs to make America lead in superweapons race. In 2012, the Citizens for Responsibility and Ethics in Washington and the Brave New Foundation non-profit organizations found that 70 percent of retired three-and-four star generals took jobs with defense contractors or consultants. Defense contractors enjoy great influence among lawmakers. Megaprojects are launched, huge sums are spent but no wonder weapons appear. Super-high-frequency guns, long-range lasers, and climatic weapons and cruise missile swarms and other sci-fi weapons are used only in Hollywood movies.
The answer to the question who is leading in the “cost-efficiency” race leaves no place for doubt.


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Chris & Sophie’s wedding – sneak preview!
Yesterday we headed up to Cheltenham Beach in Auckland to photograph Chris & Sophie’s wedding.
Their ceremony had to be moved from the original location on the beach as it was pretty windy & cold, so instead they had it indoors at their reception venue, McHugh’s restaurant.
We were racing against daylight for the photo shoot, which took place at North Head, along with some cool beach shots down at Cheltenham. Being a Thursday wedding, those locations were nice & quiet, and the fading evening light looked amazing for photos – especially looking out over Rangitoto with a little extra light thrown in to bring the focus on to them
It was a really fun wedding – thanks to you both for inviting us to share in your day!
More photos to come soon!
- Isaac de Reus
- View full post


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This issue’s shoptalkers: Glen Bolger, partner and co-founder of Public Opinion Strategies; Harrison Hickman, founder of Hickman Analytics; Alex Lundry, vice president and director of research at Target Point Consulting; and Matt Hogan, vice president at Anzalone Liszt Research.
C&E: Is the cellphone-only problem the biggest challenge for pollsters going forward?
Glen Bolger: You want the sober answer or the drunk answer?
Harrison Hickman: The cellphone problem gets worse over time and here’s why: someone living in Northern Virginia gets a cellphone and then they move to suburban Atlanta. So even if you’re sampling suburban Atlanta cellphones, you’re going to miss that person. The one thing I think we could all agree on if we were kings of the world is that telephone exchanges would all be contiguous.
Matt Hogan: It’s a real problem.Cellphone-only households are now a third of the country and we’re continuously shocked by how many pollsters are still not using cellphones in their samples. Maybe you could get away with it in 2010, but not next year. Thankfully it’s getting a little cheaper, but it’s still tough for campaigns to pony up. If you want an actual representative sample you need to spend the money on this.
Bolger: And that’s the real issue. Matt hit on it directly. It’s more expensive to interview cellphones. Doing it on the national level is obviously easy. But on the statewide level it’s tougher. Some statewide campaigns have enough money and realize they need to do it, but that’s not all campaigns. The other thing is that you can’t do cellphone interviewing below the statewide level on a fairly rigorous basis. If you call someone in Northern Virginia and reach them on their cellphone, you can’t ask what congressional district they live in. They’ll say, “Beats the hell out of me.”
Alex Lundry: The problem gets even worse when you look at cell-mostly households like mine. We have a landline in the house, but nobody knows the number and whenever anyone calls it we look at the caller ID to see if we want to pick it up. This is another 15 to 20 percent of the electorate.
Hickman: And you can’t make up for it by weighting. You used to be able to just adjust the number of people who are under 35 and weight them more. But the people who are landline only have a fundamentally different lifestyle and attitude, so you can’t make the traditional adjustment.
Lundry: The agency that actually tracks cellphone versus landline is the Center for Disease Control. They have an interest in tracking it because one of the first initial differences between the cellphone-only population and the landline population was on health issues. People with cellular service only were more likely to binge drink, use illicit drugs, have STDs…
Bolger: Vote Democrat. (laughter)
Lundry: Right. As that cellphone-only population has grown, though, we’re finding there are real partisan differences between the groups, too. We’ve been getting away with not doing this for a while. Now, I think it’s malpractice for a pollster to not offer a quote that includes cellphones.
Hickman: These public polls that rely exclusively on computer assisted interviewing are going to start making huge errors because they can’t reach the cellphone-only population.
C&E: How frustrating are public polls, especially when a bad poll gets attention in a race you’re working?
Bolger: They’re mostly background noise. The issue for me is when they’re automatically presumed above it all and the campaign pollsters are the ones presumed suspect. The case I make is the exact opposite. If our polls are wrong and we’re giving bad data to our campaigns, we don’t get hired anymore and we don’t get to feed our families. If the media poll is wrong they just say, “Well, this ad clearly changed things in the past two days.” The idea that media polls are somehow superior is the one thing that gnaws at me. I’m not going to give happy data to a client and then after they lose say, “Sorry, our data was totally wrong.”
Hickman: And media organizations are more budget constrained than campaigns are. It’s sort of difficult for people to believe sometimes, but a TV station may have $12,000 set aside for this kind of project. A campaign would be paying $25,000 for the same poll. So of course we can do it better.
Hogan: It’s just frustrating how many of them don’t release their demographics. They’ll release some poll that shows a big shift and really drives the narrative for a couple of days. In reality, there probably wasn’t any shift at all and their sample is just more Republican or Democrat than it was in the previous poll. Reporters are getting a little better about covering that and picking up what the sample is, but too few of these media pollsters release all their data.


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The UFC returns after a one-week hiatus on Saturday with UFC Fight Night 189, which takes place at the UFC Apex in Las Vegas with a lineup that streams entirely on ESPN+.
A heavyweight main event tops the card. Jairzinho Rozenstruik (11-2 MMA, 5-2 UFC) and Augusto Sakai (15-2-1 MMA, 4-1 UFC) will look to rebound from defeats in their previous headlining spots when they clash in a five-round bout.
For more on the numbers behind the card, check below for 30 pre-event facts about UFC Fight Night 189.
Jairzinho Rozenstruik vs. Augusto Sakai
Rozenstruik has earned 10 of his 11 career victories by stoppage. He’s finished all of those wins by knockout.
Rozenstruik’s nine-second knockout at UFC on ESPN+ 12 is the second fastest in UFC heavyweight history behind Todd Duffee’s seven-second finish at UFC 102.
Rozenstruik’s knockout of Alistair Overeem at the 4:56 mark of Round 5 at UFC on ESPN 7 marked the third latest stoppage in UFC history behind Demetrious Johnson’s win (4:59 of Round 5) at UFC 186 and Yair Rodriguez’s victory (4:59 of Round 5) at UFC Fight Night 139.
Marcin Tybura vs. Walt Harris
Marcin Tybura’s (21-6 MMA, 8-5 UFC) four-fight UFC winning streak at heavyweight is tied for the third longest active streak in the division behind with Francis Ngannou (five) and Ciryl Gane (five).
Tybura defends 82.1 percent of all opponent takedown attempts in UFC heavyweight competition, the best rate in divisional history.
Walt Harris (13-9 MMA, 6-8 UFC) fell to 6-6 (with one no contest) since he returned to the UFC for a second stint in April 2016.
Harris has earned all 13 of his career victories by knockout.
Harris’ 12-second knockout of Aleksei Oleinik at UFC on ESPN 4 is the third fastest in UFC heavyweight history. Todd Duffee holds the record with a seven-second finish at UFC 102.
Santiago Ponzinibbio vs. Miguel Baeza
Santiago Ponzinibbio (27-4 MMA, 9-3 UFC) has earned 21 of his 27 career victories by stoppage. He’s finished 16 of them in Round 1.
Ponzinibbio’s four first-round knockout victories in UFC welterweight competition are tied for third most in divisional history behind Anthony Johnson (five) and Vicente Luque (five).
Miguel Baeza (10-0 MMA, 3-0 UFC) has earned eight of his 10 career victories by stoppage. That includes all three of his UFC wins.
Baeza is one of 11 fighters in UFC history to earn a knockout stemming from leg kicks. He accomplished the feat at UFC on ESPN+ 19.
Tom Breese vs. Antonio Arroyo
Tom Breese (12-3 MMA, 5-3 UFC) is 2-2 since he moved up to the UFC middleweight division in May 2018.
Breese has earned 11 of his 12 career victories by stoppage. All four of his UFC finishes are by knockout.
Makwan Amirkhani vs. Kamuela Kirk
Makwan Amirkhani (16-5 MMA, 6-3 UFC) is one of three fighters in UFC history to earn multiple submission victories by anaconda choke. Phil Davis and Charles Oliveira also accomplished the feat.
Amirkhani’s three submission victories in UFC featherweight competition are tied for third most in divisional history behind Oliveira (six) and Chas Skelly (four).
Tanner Boser vs. Ilir Latifi
Ilir Latifi (14-8 MMA, 7-6 UFC) returns to competition for the first time since Feb. 8, 2020. The 483-day layoff is the longest of his more than 13-year career.
Latifi’s three-fight losing skid is the longest of his career. He hasn’t earned a victory since February 2018.
Latifi was unsuccessful in his UFC heavyweight debut at UFC 247 in February 2020.
Francisco Trinaldo vs. Mulsim Salikhov
Francisco Trinaldo (26-7 MMA, 16-6 UFC) makes his UFC welterweight debut after previous victories with the organization at middleweight and lightweight.
Trinaldo’s 15 victories in UFC lightweight competition are tied for fourth most in divisional history behind Jim Miller (19), Donald Cerrone (17) and Gleison Tibau (16).
Trinaldo’s 12 UFC victories in Brazil are the most in company history.
Trinaldo is the only fighter in UFC history to earn two arm-triangle submission victories from half-guard.
Trinaldo’s nine decision victories in UFC lightweight competition are second most in divisional history behind Tibau (11).
Montana De La Rosa vs. Ariane Lipski
Montana De La Rosa’s (11-6-1 MMA, 4-2-1 UFC) three stoppage victories in UFC women’s flyweight competition are third most in divisional history behind Gillian Robertson (five) and Valentina Shevchenko (four).
De La Rosa’s three submission victories in UFC women’s flyweight competition are second most in divisional history behind Robertson (four).
Claudio Puelles vs. Jordan Leavitt
Jordan Leavitt (8-0 MMA, 1-0 UFC) is one of 12 fighters in UFC history to earn a knockout stemming from a slam. He accomplished the feat at UFC on ESPN 19.
Leavitt’s 22-second slam knockout at UFC on ESPN 19 is tied for the second fastest in UFC history behind Josh Burkman’s 21-second win at The Ultimate Fighter 2 Finale in November 2005.
Leavitt is one of five fighters in UFC history to earn a knockout victory with just one significant strike landed in a fight.
Leavitt’s 22-second victory at UFC on ESPN 19 is the fastest finish for a debuting lightweight in UFC history.
UFC research analyst and live statistics producer Michael Carroll contributed to this story. Follow him on Twitter @MJCflipdascript.

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