Hong Kong bookseller Lee Bo will abandon UK residency
March 1, London: One of the five booksellers who went missing from Hong Kong has said he will abandon UK residency.
He said in a televised interview, Lee Bo denied he had been abducted by Chinese officials. It was his first public appearance in TV since going missing last year.
Lee is one of five men linked to a Hong Kong publishers who disappeared late last year - the publishing house sold books critical of China's leaders, reports said.
In his interview with mainland news outlets, in China, Lee, also known as Paul Lee, confirmed that he has a British passport, and that he had applied for the right to house in the UK in the early 1990s.
Political activists who have been advocating for Lee's return to Hong Kong believe his apparent confession is laughable, local news reported. Public confessions have long been a part of China's criminal law, but experts say many confessions are forced.
The other booksellers also appeared on Chinese television on Sunday, saying they were detained for "illegal book trading".
The case of missing booksellers has sparked accusations of China violating Hong Kong judicial independence, reports said.
The Oslo Times


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With 46000 acres of nature to explore your children will never get bored. We will utilize kayaks and stand up paddle boards to access some of the most pristine ecosystems Northeast Florida has to offer. Days are filled with travel to new exciting locations within the Timucuan Preserve such as hiking the Talbot Islands State Park, kayaking to Kingsley Plantation and SUP boarding at Huguenot Park. Each location has a historic and ecological focus. This is a very active program with water sports every day (kayaking, swimming and paddleboarding).
Thru crafts and hands-on activities the campers learn about the human and natural history of the area. They'll keep a daily journal to share their adventures with you. Campers will leave with a tangible memory of all they have learned and explored. Activities are perfect for kids 7-14 years old. Our groups are small, 12 campers / week with 2 adult councelors and a Jr Councelor. There are four week long camps for 7-10 year olds and two weeks for 10-14 year olds. Hours are 9am-4pm / Monday- Friday, kids bring their own lunch each day.
Week 1 - June 10-14 - 10-14 year olds Almost Full
Week 2 - June 17-21 - 10-14 year olds Almost Full
Week 3 - June 24-28 - 7-10 year olds Almost Full
Week 4 - July 8-12 - 7-10 year olds
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Week 6 - July 29- Aug 2 - 7-10 year olds
June 10 - 28, July 8 - August 2, 2019
Grades: Elementary, Middle School, High School
Area: The Beaches, Northside / NW Nassau County
13030 Heckscher Dr., Jacksonville, FL, 32226

domain: geography


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A team led by researchers from JNU and ICGEB, New Delhi has identified a molecule that prevents malaria parasites from invading red blood cells (RBCs) and causing the disease. It prevents the interaction between parasites and receptors found on RBCs thereby preventing the parasites from invading the RBCs. Since the molecule targets the receptors found on RBCs, it can be used even against drug-resistant malaria parasites.
Researchers from New Delhi have for the first time deciphered a multiprotein complex that is involved in the invasion of the red blood cells (RBCs) by Plasmodium falciparum malaria parasites. They have also identified a peptide molecule from the codon-shuffled library that can effectively prevent the interaction between malaria parasites and receptors found on RBCs thereby preventing the parasites from invading the RBCs and causing the disease.
During infection with Plasmodium species, the merozoite form of the parasite invades RBCs and replicates inside them. It is during the blood-stage of infection that malaria disease occurs.
P. falciparum parasites are known to quickly develop resistance against drugs. This is because the parasites undergo mutations thereby making the drugs that target the parasites ineffective. A team led by Dr. Anand Ranganathan from the Special Centre for Molecular Medicine at Jawaharlal Nehru University (JNU), New Delhi and Dr. Pawan Malhotra from the International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi has used a different approach to overcome the problem of drug resistance.
Instead of targeting the parasite, the peptide molecule identified by the researchers targets a specific receptor — cyclophilin B — found on the surface of RBCs that are used by the parasites to bind and invade them. Since the peptide molecule binds to cyclophilin B receptors, the parasites are unable to bind to receptors and invade the cells.
In experiments carried out in test tubes, there was about 80% reduction in parasite invasion of RBCs.
“Unlike the malaria parasites, the red blood cell receptors will not undergo mutation. That is why we were able to target the receptors and prevent the invasion of RBCs by even the drug-resistant malaria parasites. That’s the advantage of targeting the host protein [receptor] that is essential for the pathogens to infect the cells,” says Dr. Ranganathan.
Cyclosporine A drug
An immunosuppressive drug (cyclosporine A) that binds to cyclophilin B receptors on RBCs is effective in killing malaria parasites. Studies on mice model by the researchers showed that cyclosporine A drug reduced invasion by malaria parasites by about 80% when RBCs were treated with 100 microMolar of the drug; the reduction in invasion of RBCs by the parasites was about 80% when 50 microMolar of the drug was directly added into the culture.
“But in mice model it has been shown that the drug has adverse effects as it also kills RBCs. Using the drug in two different experiments we confirmed that cyclophilin B receptors were involved in the invasion process,” says Dr. Prem Prakash from ICGEB and the first author of the paper published in Nature Communications.
“We found multiple sets of interactions between parasites and human RBCs,” says Dr. Mohammad Zeeshan from ICGEB and the other first author of the paper. There are two main receptors on RBCs and two proteins of the parasite which form a four-protein complex.
“By interrupting the binding of the parasite protein with RBCs at one of the receptors the whole protein complex falls apart. It is like a number-lock with a four-digit combination. Interrupting any one of the steps will prevent the parasite invasion of RBCs,” says Dr. Ranganathan. “We are looking at peptides that can bind to each of the four targets. The long term goal is to add the four peptides together to achieve total inhibition of parasite invasion.”
At 25 microMolar, the dosage used in the experiments is very high. Having deciphered the mechanism of parasite entry, the team is now working to reduce the dosage to use the peptide as a drug. “We can either modify the cyclosporine A drug to make it less toxic and use it for preventing malaria or use the peptide molecule as an inhibitor. It is easier to take the drug than the peptide to clinical testing by making necessary modifications,” says Dr. Malhotra.

domain: biology


Yorba Linda’s early history as a city after incorporation was finally achieved in 1967 revolved around keeping the community as a low-density residential enclave in the North County area.
The city’s couple thousand voters were unhappy with the first City Council’s actions related to density levels, and, by 1972, they had replaced all five of the originally elected members.
For several decades, most of the city’s council elections featured candidates who strongly supported what was called a low-density, semi-rural lifestyle backed by zoning regulations.
In fact, according to an oral history interview conducted with the long-serving city manager at the time, early council arguments swirled about the best density levels for the city: 2 units or 2.5 units per acre.
Of course, times change, and due to state legislation, cities are now forced to create zoning that would allow higher density development, with specified allotments for very low- and low- income households.
Now, Yorba Linda, along with other like-minded cities, is reduced to sending letters opposing similar legislation, including last year’s Senate Bill 9, which provides methods to increase the state’s housing supply to alleviate California’s housing crisis.
The council’s most recent letter, approved on a unanimous vote June 21, was sent to Buffy Wicks, who chairs the state Assembly’s Housing and Community Development Committee that’s now considering AB 2011, the Affordable Housing and High Road Jobs Act of 2022.
The bill would require cities to ministerially approve certain affordable and mixed-use housing developments in zones where office, retail or parking are the principally permitted use. The approval would be without condition, even if inconsistent with a city’s general plan or zoning.
A draft of an opposition letter says: “Eliminating opportunities for public review of housing developments goes against the principles of transparency and public engagement. Public hearings allow members of the community to inform their representatives of their support or concerns.”
* * *
Yorba Linda’s voter turnout in the June 7 primary election topped other North County cities at 41.8%, with 20,067 of 47,994 registered voters casting ballots. Most voted by mail, 17,156 or 35.7% of the city’s registered votes. Vote center ballots were cast by 2,911 voters, or 6.1% of registered voters.
Democrat Gavin Newsom captured the largest number of votes in the city, with 6,268, and Republican Brian Dahle placed second with 4,690. However, the vote total for all of the Republican candidates in the race easily outdistanced the total for all of the Democrats.
Yorba Linda’s vote count for the city’s representative in Congress was 9,204 for Young Kim, 5,563 for Asif Malmood, 4,248 for Greg Raths and 220 for Nick Taurus. Republican Kim and Democrat Malmood advance to the November general election ballot based on tallies from all cities.
Jim Drummond is a longtime Yorba Linda resident. He gives his opinion on local issues weekly. Send e-mail to firstname.lastname@example.org.


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Jema Lee is an expert in living your best life through your menstrual cycle. She works as a women’s health educator. She’s worked exclusively with women for the last 7 years and has worked in the health field for 14. She does ayurvedic coaching and psychology, chakra and spiritual work and nutrition. Nutrition is where she started and she saw how many people were not helped well and wanted to provide better support. She has PCOS and has gone through the work of rebalancing her body through getting to know her cycle.
Your menstrual cycle relates to everything. It relates to how you eat throughout the month to how you move, to your emotions, your moods, your energy, your gut health, your general passion for life, your creativity, so even though it’s menstrual cycle, it has nothing to do specifically with just your bleeding time, IT’S YOUR ENTIRE LIFE AS A WOMAN.
We go through the same internal shifts through our cycle and it’s ok to go through these waves. More and more women are having challenges with their endocrine system. It’s really important to recognize that we can burn ourselves out so easily by trying to fit into the masculine mold.
What are the four phases of the menstrual cycle?
WINTER. Winter is our menstrual cycle.
SPRING. Spring is our follicular phase.
SUMMER. Summer is ovulation.
FALL: Fall is our luteal phase.
“I call it homecoming. It’s very coming home in your body and recognizing “hang on, don’t be so hard on yourself. There’s a lot going on and your body is very much changing all the time.”
How have I felt today emotionally?
What have I physically been wanting to do today?
What am I craving? What are the foods I’ve been called to eat?
How can we help remove the shame around catering to our cycles?
How you feel today is only going to happen 12 more times in the next 365 days because we’re cyclical.
We need to educate our youth better in the first place!
Let’s deep dive into the cycles:
Menstruation is the first phase of your cycle and begins on the day of your first full bleed. Inner winter begins on the first full day of bleeding. Anything that agitates you, this is what I call a cycle sign. This is just your body showing what you need to care for.
PMS = Period Messages of Self-Care.
Inner spring is the follicular phase and is usually a surge of energy, typically around day 7. Usually cooler/crisp foods sound good, creativity is surging, working-out hard is most possible and we’re feeling more outgoing.
Ovulation is the shortest phase of our cycle and is known as Inner Summer or the Beyonce season. This is when we feel flirty and sexy and a time when we want to be seen. This is a great time to try new things and be social.
Being able to plan your calendar around your cycle is so powerful! So much productivity and peace can come from this. Its about becoming attached to the process instead of just the outcome.
Where can we start? What’s a few things we can start doing today to get us more in tune with our body and our menstrual cycle?
Start using a written menstrual tracker. Apps are great, but written can help you see more clearly what is lining up.
Ask yourself each day “how do I feel today?” without judgement and just observe.
How do you like to manage your period?
I like to stretch or walk, sleep more and eat warm, healing food. I love using a castor oil pack on my belly. I take it easy at work and at home.
Where can we find you?

domain: medical


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The history of the Taiwanese democratisation is usually interpreted by elites from different political parties, who often neglect the real faces and lives of individuals participating in the rallies. The director, a confused twenty-something, looks back upon the 40-year history of democratisation in Taiwan through the life experiences of two veteran grassroots activists. He attempts to discover the causes of their actions and decisions to be lefties as well as their limitations.
Producer: Jewel Chen-lin LAI Total Budget (USD): 120,000 Funding in Place (USD): 100,000 Running Time: 100 mins Year of Completion: 2018 Language: Chinese , ,Minnan Language Subtitles: English , Chinese Director: LIAO Jian-hua
LIAO Jian-hua was born in Chiayi, Taiwan. His first feature-length documentary The Last Insurrection was shortlisted in the Taiwanese Competition of Taiwan International Documentary Festival and the Asian Competition of DMZ International Documentary Film Festival in 2016. Through in-depth interviews and research, the film re-examines the Taiwan Independent Association Incident in 1991.
Jewel Chen-lin LAI
Jewel Chen-lin LAI received her Master in Film and Screen Study from Goldsmiths College, University of London. She has organised two editions of the acclaimed CNEX Documentary Film Festival and founded Dot Connect Studio in 2012. She currently works as a film producer and festival programmer.

domain: artistic


From old favorites like the Beach Boys to some newer artists, these ten albums will heat up (or mellow out) your summer.
David Bowie was a chameleon. And the “colors” in his music came from an array of inspirations, from jazz to rock, to the very unexpected.
Rock stars spend their lives on stage. But do those performing skills translate to the silver screen? Sometimes yes. Sometimes…not so much.
We all know about how American blues and early rock influenced some great groups. But what about some other surprising other musical genres?


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domain: entertainment


Handwoven Banarasi Katan Silk Lehenga in Hot pink and orange dual tone
This lehanga has 12 kali or panels with that are sufficient for around 4.5 meter ghera or circumference at the bottom. The lehenga is fit for up to waist 38.
Banarasi borders have been added to a pure organza dupatta and meenakari brocade blouse fabric is included
Color - Pink and Orange dual tone
Weaving - Kadhwa


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TORONTO, July 17, 2014 /CNW/ - The Ontario Human Rights Commission (OHRC) took another step to eliminate racial profiling in Ontario by speaking out in the Office of the Independent Police Review Director (OIPRD) systemic review of the OPP practices for obtaining voluntary DNA samples. The OHRC is troubled by allegations that the Ontario Provincial Police (OPP) engaged in racial profiling when requesting DNA samples from migrant workers near Vienna, Ontario as part of a sexual assault investigation in October and November 2013.
"Racial profiling in any form causes great harm to individuals and in many cases entire communities. We will continue to speak out when we see it happening anywhere in Ontario," said OHRC Chief Commissioner Barbara Hall.
In December 2013, "Justicia for Migrant Workers" (J4MW), a non-profit group that promotes the rights of migrant farm workers, filed a complaint with the OIPRD alleging that the police collected DNA samples from approximately 100 "Indo and Afro-Caribbean" male migrant workers who did not match the suspect description apart from their dark skin colour. On March 3, 2014, the OIPRD announced that it was conducting a systemic review of the OPP's practices for obtaining voluntary DNA samples from specific groups. Racial profiling is a key allegation in J4MW's complaint, and a key component of the OIPRD's review.
The OHRC is concerned that the allegations are consistent with racial profiling, and has delivered a submission to the OIPRD sharing its expertise in racial discrimination and profiling. In particular, the OHRC is concerned that:
- The workers were targeted mainly because of race and stereotypes that Black men and migrant workers are prone to criminal behaviour
- The requests were coercive, as migrant workers are particularly vulnerable and rarely seek to assert their rights for fear of being sent home
- The OPP practice of seeking voluntary DNA samples in investigations has a disproportionate impact on racialized groups and marginalized communities.
Racial profiling is prohibited under Ontario's Human Rights Code but remains a daily reality for Aboriginal Peoples and members of racialized, particularly Black, communities in Canada. The OHRC continues to hear about racial profiling that includes unreasonable questioning, requests for identification, retaining personal information, intimidation, searches, aggression – and now, potentially, DNA sampling.
The OHRC has been involved in many cases addressing racial profiling, as well as partnering with various police services and boards in Ontario, including a multi-year Human Rights Project Charter with the Toronto Police Service, and similar ongoing partnerships with the Windsor Police Service and Ontario Police College. These efforts aim to embed human rights in all aspects of operations so that police services can meet the changing needs of an increasingly diverse population.
Aussi disponible en français
SOURCE: Ontario Human Rights Commission
For further information: Afroze Edwards, Senior Communications Officer, Ontario Human Rights Commission, 416-314-4528

domain: news


text:
Exploration of Art
Jewelry, pottery, mixed media, assemblage, fabric, art dolls, fashion, and anything that glitters. I love to create and share my creations made with love to the world. My exploration of art has given me many outlets for creating and my imagination has given birth to many one of a kind creations. I love found objects, twigs, gems, and any thing that sparkles. Please feel free to wander through my pages of creations and hopefully you will find my piece of art that was waiting for you.
Art means many things to different people and making the creation that is right for you is my goal.
International orders are welcome. Please send me an email at Dixiearthouse@aol.com and I will let you know what your shipping costs will be.


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Days Of Palestine – Ramallah
In a sudden increase in the positive coronavirus cases in the West Bank, from none to one or two cases in the last few days, the Ministry of Health said today that 10 cases have tested positive bringing overall total in Palestine, not including occupied Jerusalem, to 284.
Palestinian Ministry of Health spokesman Kamal Shakhra said in the daily briefing on the disease that five of the new cases were for people from the town of Izzarieh, east of Jerusalem, three from Rafat in Ramallah area, one from Jenin in north of West Bank and one from Hebron in south of West Bank.
There are also unconfirmed 36 corona cases in occupied East Jerusalem, which would bring total in all the occupied Palestinian territories to 320.
Total number of cases in the West Bank is currently 271 and 13 in the Gaza Strip. A total of 62 have recovered with more recoveries announced today, nine of them are in the Gaza Strip.
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Two have died of the virus in the West Bank.
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Welcome to the St. Catherine of Siena Religious Education website. We are glad you're here!
Just because summer looks different this year, doesn't mean it's canceled! There are still many fun things families can do to grow, learn and play together. Click the image above to learn more!
resources to talk with your kids about racism
The explosion of riots and protests that erupted across the US this summer have revealed that racism remains an issue. Even if your younger children didn't see any of the videos or protests themselves, they are undoubtedly aware of the unrest in our country. Certainly, older children and youth have seen and read a lot already, from different news sources. One of the most important things you can do this summer is to find the time to have some discussions about racism. The resources below can get you started.

domain: sociology


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When Manchester United's 5-0 humilation against arch-rivals Liverpool at Old Trafford was complete on Monday morning (AEDT), one block of loyal fans stayed behind, bellowing the manager's name as they stood arm in arm.
There was just one problem - it was the travelling away supporters.
There couldn't be a more perfect metaphor for the canary in the coalmine than the one that came in the form of a couple thousand Liverpool fans, co-opting and ironically chanting their support for a manager whose time seems well and truly up.
Solksjaer is in a unique spot - he seems to be constantly backed, or at least not criticised as heavily as others would be, by pundits on English television, while simultaneously being ripped to shreds by those who once sang his name from the stands.
Gary Neville is one of the most respected voices in English football, but he's also someone who has a long-time friendship with Solskjaer - and despite repeated criticisms of the tactical setup, refuses to suggest that the club needs to move on.
Another member of United's 1990s powerhouse sides, Paul Scholes, harangued Solskjaer for his tactics but focused most of his attention on midfielder and perennial easy target Paul Pogba.
You can argue if Solskjaer is the right man for the job. What you can't argue is he is being afforded a lot of rope because of who he is, and who the television tastemakers are.
Watch Messi, Neymar, Ronaldo and football's biggest superstars in the UEFA Champions League with every match streaming ad free, live and on demand only on Stan Sport. Start your seven day free trial here!
Rightly or wrongly, there are many on both sides of the camera who incorrectly conflate making tough personnel decisions with spitefulness and negativity.
Much like calling for a player to be dropped due to poor performance is often seen as a personal attack towards the person in question, the idea that a coach should be relieved of their duties causes some people to bristle at the notion of 'talking about another man's job'.
If Solksjaer isn't good enough for the job, and the tepid football played by one of the most expensive squads in the world is evidence of that, then it should be a relatively straight-forward decision.
Sacking club legends is often difficult - in Australia, the Roosters cut ties with Brad Fittler after a dreadful 2009 season. In the next decade, they made four grand finals and won three premierships.
Manchester United's supporters have well and truly turned on the manager, despite his standing within the club's history. And while you can sometimes gauge the effectiveness of a decision by canvassing your own fans, it's the reaction of your rivals that usually tells you more.
And right now, fans of Liverpool, Chelsea, Manchester City, Leeds United, and all of the Red Devils' other enemies are facetiously pleading with Ed Woodward to give Ole more time in the job.
Names have been thrown out as potential replacements include former Chelsea boss Antonio Conte, Real Madrid icon Zinedine Zidane, and current Ajax manager Eric ten Hag.
All would, on face value, be a significant upgrade for a club that once steamrolled all comers both domestically and in continental football.
It's not clear if Manchester United will move on from their manager soon, but it certainly seems like they should.


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domain: health


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- GeoRef, Copyright 2008, American Geological Institute. Reference includes data from Bibliography and Index of Geology Exclusive of North America, Geological Society of America, Boulder, CO, United States
Diagenetic replacement phenomena involving dolomite, silica, and calcite are demonstrated from oolitic horizons in the Cambro-Ordovician 'Durness' carbonates of northwest Scotland. The oolite texture of the rocks has exerted a control over the patterns of diagenesis and facilitates the interpretation of the diagenetic history. A possible five-stage diagenetic sequence is proposed to account for the observed relationships of the recrystallization and authigenic phenomena. A dilemma regarding a void filling interpretation of drusy calcite textures is demonstrated and arguments favoring the use of the term 'calcitization' rather than 'dedolomitization' are offered.


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COFA Talks Online
A Lesson in Ballen Photography
Watch this on your iPod - Vodcast available here
Roger Ballen takes us on a journey through 25 years of his work documenting the marginalised rural communities of South Africa,
Here for the 17th Biennale of Sydney, Roger asks some of the big questions in documentary photography, about objectivity and assembling the intricate details that tie each photograph together.
Ballen's images have been described as dark, strange and humorous. He discusses the undefined territory between fiction and reality and how nothing is repeatable.
This talk was recorded on Cockatoo Island on the 15th of May, 2010 for the 17th Biennale of Sydney
More about Roger Ballen


An ideal vessel for long stays on board and for long distance tripsOne of the most beautifully built Sturier with lots of extra equipment and lots of luxury. This vessel belongs to the first owner. Underwater hull blasted and treated in 2018 !
GENERALHull shape: Multi chine with bilge keelsRudder: SingleSteering system: Steering wheel - hydraulicWindows: Double glass brand GeboDisplacement: +/- 15.900 Kg.Other: A very high quality built motor yacht with all modern conveniences
ACCOMMODATIONMaterial, colours: Classic interior teakCurtains: Cream curtainsSaloons: Version with 2 cabinsCabins: 2Berths: 2 + 2Headroom: +/- 1.90mBath: 1Television: Present at dinetteCooker & fuel: Ceramic 4 ringsOther: A spacious 2 cabin vessel with steering position, bathroom and dinette, KVH TV tracking system
ENGINE, ELECTRICS, WATERPower: 1 x 135 HPNumber of identical engines: 1Year: 1997Fuel tanks: +/- 800 LCooling system: Via seawater and internal coolingPropulsion: Propeller with propeller shaftMeasuring instruments: Present at steering positionDynamo: 24V - 84 Ah.Water system: Hydrophoric pump 2016Hot water: Via 40 L calorifier and engineWater tank & material: +/- 700 L S/sWaste water tank: +/- 200 LShorepower: 220V with cableTachometer: PresentWater tank gauge: PresentFuel tank gauge: PresentOil pressure gauge: PresentTemperature gauge: PresentOther: Cable engine control, halogen lighting, 220V sockets, 4 blade propeller, 3 x windscreen wipers
NAVIGATION AND ELECTRONICSRudder position indicator: SimradCharts, guides: On requestOther: All important navigation equipment is present to make long trips over the sea
EQUIPMENTAnchor windlass: ElectricFenders, lines: PresentSea rails, pushpit, pullpit: Present in stainless steelOther: Solid teak deck in the cockpit and on the side decks, washer/dryer
SAFETYCE-standard: CE-AOther: A particularly beautiful and very well maintained motor yacht built by a well known shipyard


Friday, April 25, 2008
New Life In North Fork......Continued
The weather and Springtime has not been cooperating at all this year. It has been miserably cold and unpredictable for us humans for weeks, but still our resident returning sparrows have braved the weather, and have been very busy transporting nest building materials to the nest site. Look closely and you can see two long wing feathers as Mom is tidying up the nesting area.
This year the neighbors and I decided to help out our industrious sparrows, note the mound of nest building material consisting of lint, tiny sticks, fluff, and, string hanging from the red bud tree.
At first the wary sparrows were more cautious than thankful for the scary cocoon looking mound of nest material as it tumbled and twisted in the wind. The sparrows soon discovered, however, that the odd looking cocoon was a much easier way to obtain building materials than darting all over town.
As attested by Dad sparrows mouth full of fluff, our offered up cocoon appears to be a very successful helpful hand.
Here is Father sparrow on the constant look out for danger as Mom is arranging the nest to suit her fancy.
Even Moms need to take a rest occasionally..............
Stay tuned for more reports on our returning sparrow family.
© Copyright 2008 North Fork News


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Scientific Testimony: Its Roles in Science and Society (Hardcover)
Scientific Testimony concerns the roles of scientific testimony in science and society. The book develops a positive alternative to a tradition famously expressed by the slogan of the Royal Society Nullius in verba ("Take nobody's word for it"). This book argues that intra-scientific testimony--i.e., testimony between collaborating scientists--is not in conflict with the spirit of science or an add-on to scientific practice. On the contrary, intra-scientific testimony is a vital part of science. This is illustrated by articulating epistemic norms of intra-scientific testimony and arguing that they are vital to scientific methodology on a par with other scientific norms governing scientific observation and data analysis. The book also provides an account of public scientific testimony--i.e., scientific testimony to the lay population. This is done by integrating philosophical resources with empirical research on the science of science communication. For example, various misconceptions about science and folk epistemological biases are diagnosed as factors that contribute to science skepticism. This diagnosis provides the basis for developing novel norms for science communication that are sensitive to the psychological and social obstacles to laypersons' uptake of it. Finally, the volume discusses how public scientific testimony is best embedded in society and argues that it is critical for societies that pursue the ideals of deliberative democracy. Scientific Testimony draws on philosophy of science, social epistemology, and empirical research to provide a wide-ranging account of the roles of scientific testimony within scientific practice and within the wider society.
Mikkel Gerken, Professor of Philosophy, University of Southern Denmark Mikkel Gerken is a Danish philosopher. His recent research concerns epistemology and philosophy of science but it is often integrated with theories of language and communication, cognitive psychology, philosophy of mind, and philosophical methodology. Professor Gerken was an Associate Professor at the University of Edinburgh before returning to his native Denmark, where he is now a Professor at the University of Southern Denmark. He is an associate editor of Ergo - an open access journal of philosophy. He has been William H. Bonsall Visiting Associate Professor at Stanford University. He was an elected member of The Young Academy under the Royal Danish Academy of the Sciences and was awarded a Young Elite Researcher prize from the Danish Council for Independent Research.

domain: library


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JetBlue announced it intends to launch multiple daily flights from Boston and New York to London in 2021, the carrier’s first European destination.
The new routes, which will be served by Airbus A321LR single-aisle aircraft with a reimagined version of Mint, will mark the first-ever transatlantic service offered by the airline.
JetBlue is evaluating which London airports it will serve.
“Twenty years ago, our founders had a simple formula for choosing a new market, it had to be overpriced, underserved, or both,” said Joanna Geraghty, President
The airline’s Mint premium experience, which disrupted transcontinental travel in the U.S. with accessible fares and a thoughtful reinvention of the business class cabin, promises to offer transatlantic customers a fresh choice.
Growth into Europe is the next natural step in JetBlue’s focus city expansion strategy, with London being the largest destination not served by JetBlue from both New York and Boston. The new service will strengthen JetBlue’s relevance in its two largest focus cities while also answering calls from loyal business and leisure customers who have, until now, been forced to fly other carriers to and from London.
The highly anticipated announcement, which comes after an extensive internal review, was made in New York at a crewmember event at John F. Kennedy International Airport. More than 1,300 crewmembers filled the airline’s hangar to hear CEO Robin Hayes and President & COO Joanna Geraghty outline the historic move for the 19-year old airline.
“The big airlines will tell you that competition has never been more robust, but the smaller airlines have never found it harder to get access,” said Geraghty. “It’s time for regulators here in the U.S. and across Europe to create conditions where smaller carriers and new entrants can thrive, instead of letting the giant airlines get even bigger through joint ventures. Given a chance to compete, JetBlue can have a tremendous effect on lowering fares and stimulating traffic.”
Travelers flying across the North Atlantic between the northeast U.S. and London have long faced sky-high fares, particularly in premium cabins, or mediocre service in a market effectively controlled by legacy carriers and their massive joint ventures. Alternatively, a handful of low-cost carriers have attempted to enter with a no-frills, bare-bones approach to flying offering little in the way of complimentary amenities or the kind of service that JetBlue has become famous for in the Americas. Particularly in Europe, JetBlue will raise the bar on what travelers can expect from a low-cost carrier.
“It’s great news that JetBlue is expanding into London and we will be delighted to welcome leisure and business visitors from Boston and New York with these new routes,” said Laura Citron, CEO, London & Partners. “North America is already London’s largest overseas market but is growing significantly year on year, so extra connectivity and capacity to allow even more people to discover our city is very exciting news. We know that Americans visit London for its exciting history and creativity, from Shakespeare to the birth of punk and the catwalks of today. This creative energy and cultural vibrancy can be felt in every aspect of London life and we look forward to sharing it with more global visitors.”
“The success Mint has had on driving down the exorbitant airfares that our competitors were charging, stimulating new demand, and forcing the entrenched carriers to up their game, is a big reason we believe London is the next natural market for JetBlue to be successful and make a positive impact on consumers,” said Geraghty.
The A321LR will allow JetBlue to tap into new long-haul markets that were not previously accessible with its current single-aisle aircraft. JetBlue will initially convert 13 aircraft in its existing A321 order book to the LR version with the ability to convert more.
“JetBlue has pioneered new travel possibilities for their customers for years,” said Christian Scherer, Airbus Chief Commercial Officer. “All of us at Airbus are honored to provide the strategic aircraft platform to enable this next chapter in the story of our partners at JetBlue.”


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You are familiar, I believe, with the authoritarian objection to a free, plural and independent media system. Authoritarian leaders always say: at this stage in the development of our country we cannot afford a free press. Too dangerous, you understand, too disruptive. Let's secure national unity first, let's get rid of poverty, let's be as rich as the West, then we can talk about a free press. Or they deploy the cultural norms argument. This is Asia, they might say, and Asian values do not support imported notions like a free press, free speech and such nonsense. Others will say: this is Africa; we have to do what makes sense in Africa. A free press causes nothing but trouble. We can't afford that now.
Well, you can imagine my reaction when I read the following story in the New York Times of Thursday November 6: 'Malay Blogger Fights a System He Perfected'. The story is about Mahatir Mohammad, the former Prime Minister of Malaysia. At 82, and five years out of power, he has become a blogger and a determined campaigner for freedom of expression. Amazing. I wish one could gather in one room all the leaders out there still imposing authoritarian control on the public sphere in the countries they govern and get Mr Mohammad in the room to express his current convictions. That would be simply fascinating to watch. I urge you to read the New York Times story.
I suppose the true moral of tales like this is: it is prudent to secure citizenship rights and the rule of law when you are in power; for you just might need those things when, at some point, you go back to being just a citizen like everybody else.
Photo Credit: Flickr user preetamrai

domain: politics


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House price rises, queues, and unaffordable rents. It’s another bubble in Irish housing. But this is different from 2008. The Irish housing system has undergone a structural “shock” in the last decade. From homelessness and mortgage arrears to the emergence of a “generation rent” that is locked out of home ownership.
Unfortunately, Government policies are worsening the crisis. Rather than providing an additional supply of affordable housing the social housing strategy is inadequate. It is too heavily reliant on the private rental and construction sector.
Meanwhile the ongoing facilitation of speculative property and financial investment in housing is adding significantly to demand. Investors bought almost a fifth of all homes in 2017, inflating property prices and rents.
Furthermore, the Government has persisted with the failed private market supply approach to solving the problem. Apartment sizes have been reduced and private infrastructure funded while house prices and rents have been encouraged to rise – aided by “demand-side” policies like “help to buy” – in order to increase the profitability of construction.
However, such policies are not increasing supply. Private developers hold monopoly positions and are hoarding land while waiting for prices to rise before building. And when they do build, “market forces” dictate that the new supply will be expensive homes for sale or expensive rentals for investor landlords.
The Irish and international experience shows that only “non-market” – State and not-for-profit -providers guarantee a sufficient supply of affordable housing.
Ireland will experience a level of housing exclusion and rising inequality, in the coming decade, on a scale unrecognisable from our current emergency
Ireland’s housing system is also worsening inequality. The “rentier class” are increasing their wealth exponentially from those living in the rental sector – mainly the poor, young and low-and-middle-income workers – and from the State through social housing schemes.
Property investors exert an undue influence over Government policy. The failure to implement long term, eg 20-year, tenant leases, protections against eviction and setting rent caps at 4 per cent rather than inflation, show how investors’ interests have been prioritised over citizens’ housing needs. The latest rental proposals do little to address these fundamental problems for tenants.
Based on the trajectory of current policy, Ireland will experience a level of housing exclusion and rising inequality, in the coming decade, on a scale unrecognisable from our current emergency, with devastating implications for our society, economy and environment.
The crisis will deepen as housing unaffordability and homelessness rise. Thousands of tenants from buy-to-let mortgage properties in arrears are likely to be evicted. Homeowners in arrears will be repossessed. All this will combine with an inadequate supply of social and affordable housing. The worst is yet to come in this latest iteration of the Irish housing crisis.
This is a defining moment. The policies implemented in the coming years will determine our housing system and housing needs of our population for decades to come
The issue is not a lack of alternative policy solutions, but rather why they are not being taken up, funded and implemented with unrelenting determination. Alternatives include: increased funding for local authorities to build; setting up a new semi-State to build 20,000 affordable “cost-rental” and “co-operative” homes per annum for a mix of incomes; enhancing tenant protections and putting the right to housing into the Constitution. The problem is that inertia, lethargy and a private market perspective dominate the State’s approach.
This is a defining moment. The policies implemented in the coming years will determine our housing system and housing needs of our population for decades to come. Is it to be a consolidation of this dystopia where housing is treated as a financialised commodity and wealth accumulating asset for investors or will our people have their need and right to a home fulfilled?
Blaming the victims
It has been shameful to see government blaming the victims of the crisis to try and normalise what is ethically unacceptable. Why are they so lacking in ambition that societal concern and solidarity is not drawn on to justify taking bold action – such as forgoing tax cuts to invest in housing or pushing for flexibility from the EU for investment?
The extent of regulatory capture of government by the property investors and financiers (who obviously do not want to see an increase in the supply of State-built social and affordable housing) means that, echoing the words of Nobel prize-winning economist Amartya Sen, a “public outcry”, of Irish civil society is required to bring about real change.
Apollo House inspired widespread public support, and it was heartening to see 10,000 attend last weekend’s Housing and Homeless Coalition protest. But the movement needs to go grow and extend across Irish society to include renters, students, precarious workers and professionals, aspirant homeowners, and those needing social housing, to protest and make housing a central electoral issue in order to pressure the State and Government to change direction before it’s too late.
Dr Rory Hearne is a postdoctoral researcher at Maynooth University social sciences institute


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Use your antibodies-online credentials, if available.
Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. 再加上，我们可以发CCL7 试剂盒 (81) 和 CCL7 蛋白 (61)和数多这个蛋白质的别的产品。
Showing 10 out of 232 products:
Enzyme-linked immunosorbent assay was used to detect the levels of chemokine (C-X-C motif) ligand 12, chemokine (C-X-C motif) ligand 7, hepatocyte growth factor, and fibroblast growth factor 1 in the supernatants of the laryngeal squamous cell carcinoma and control cells.
Periprostatic adipocytes drive prostate cancer progression in obesity via CCL7 secretion which stimulates CCR3 (显示 CCR3 抗体) expressing tumor cells.
These results suggest that let-7d may suppress renal cell carcinoma (显示 MOK 抗体) growth, metastasis, and tumor macrophage infiltration at least partially through targeting COL3A1 (显示 COL3A1 抗体) and CCL7.
Based on nasopharyngeal CCL7 gene expression in readily available Nasopharyngeal aspirate samples , we can discriminate between severity of disease in Respiratory syncytial virus infected infants.
Overexpression of ISL1 in human mesnchymal stem cells promotes angiogenesis in vitro and in vivo through increasing secretion of MCP3 and other paracrine factors.
Data indicate that different glycosaminoglycan-binding properties of monocyte chemoattractant protein-3/CCL7 and monocyte chemoattractant protein (MCP)-1/CCL2 (显示 CCL2 抗体) suggest non-redundant functions and regulation.
Our data demonstrate that the monocyte-specific chemokine (显示 CCL1 抗体) CCL7 and its receptor CCR2 (显示 CCR2 抗体) are expressed in tumour cells of RCC (显示 XRCC1 抗体)
Systemic IFN-gamma triggered the secretion of C-C motif ligand chemokines CCL2 and CCL7 leading to the egress of early, myeloid-committed progenitors from the bone marrow mediated by their common receptor CCR2.
Anticancer effect of desmethyl-lasiodiplodin is mediated, in part, by upregulation of apoptotic genes and downregulation of MCP-3.
Immunohistochemistry and real-time PCR analysis showed that CCL7 was expressed in normal colonic epithelium and the expression was higher in liver metastases compared to primary CRC (显示 CALR 抗体).
The suppression of nasal inflammation due of IL-17A (显示 IL17A 抗体) deficiency in allergic rhinitis is partly responsible for the regulation of CCL7 secretion and eosinophil infiltration, which may be regulated via the CCL7/CCR3 (显示 CCR3 抗体) pathway.
Our results demonstrate that CCL7 is required for maximal ovalbumin (显示 OVA 抗体)-induced ocular anaphylaxis, mast cell recruitment in vivo, and maximal FcepsilonRI (显示 FCER1A 抗体)-mediated mast cell activation in vitro
Data show that monocyte accumulation in the brain is dependent on chemokines CCL2 (显示 CCL2 抗体) and CCL7.
TFPI (显示 TFPI 抗体) has an anti-proliferative role in TNF-alpha (显示 TNF 抗体) stimulated-VSMCs at least partly by interfering with the MCP-3/CCR2 (显示 CCR2 抗体) pathway and then via suppression of the ERK1/2 and PI3K/AKT (显示 AKT1 抗体) signaling pathways
Our data highlight a pivotal role of CCL7 and IRF-7 (显示 IRF7 抗体) in rhinovirus-induced inflammation
tumours are characterized by expression of inflammatory chemokines (CCL2 (显示 CCL2 抗体), CCL5 (显示 CCL5 抗体), CCL7, CCL8 (显示 CCL8 抗体), CCL12 (显示 Ccl12 抗体), CXCL9 (显示 CXCL9 抗体), CXCL10 (显示 CXCL10 抗体) and CX3CL1 (显示 CX3CL1 抗体)), reflected by an enrichment of activated Foxp3 (显示 FOXP3 抗体)(-) and Foxp3 (显示 FOXP3 抗体)(+) T cells
The intranasal administration of recombinant CCL2 (显示 CCL2 抗体) (rCCL2) and rCCL7.
CCL7 has a dual role in the development of renal tubular interstitial fibrosis, deleterious in early stages but beneficial during later stages
These findings suggest that aortic MCP-3 overexpression may contribute to the development of atherosclerosis and hepatic steatosis under atherogenic conditions.
Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3.
chemokine (C-C motif) ligand 7
, C-C motif chemokine 7
, monocyte chemoattractant protein 3
, monocyte chemotactic protein 3
, small inducible cytokine A7 (monocyte chemotactic protein 3)
, small-inducible cytokine A7
, RANTES/sis homolog
, intercrine/chemokine MARC
, small inducible cytokine A7
, chemotactic protein-3


Holography as Applied to Jet Breakup and an Analytical Method for Reducing Holographic Droplet Data
Final rept. Dec 1969-May 1972
AIR FORCE ROCKET PROPULSION LAB EDWARDS AFB CA
Pagination or Media Count:
The use of holography in studying certain fluid mechanics problems was investigated. This effort specifically examined the application of holography to 1 high speed supersonic flow fields by injecting different liquid jets perpendicularly into a Mach 3 gas stream to observe how jet breakup occurs, and 2 the atomization characteristics droplet size and spatial distribution of a liquid jet injected into quiescent, atmospheric air. The holograms were recorded in the off-axis, Fresnel, transmission arrangement. The analytical method for processing three-dimensional droplet data consisted of a system of computer programs which operated on the droplet size and spatial coordinates to determine size, mass, number and spatial distribution. Two methods for retrieving holographic data were devised.
- Test Facilities, Equipment and Methods
- Fluid Mechanics


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The Joker: Grotesque and Sad But Comes with Lessons
The Joker is Batman’s wicked foe in DC comics. But this movie portrays the Joker (Juaquin Phoenix) in biographical detail way beyond the comic book Joker. Batman is only a point of reference in this story.
The Joker is the alter ego of Arthur Fleck. He has been haunted and victimized throughout his life. To defend himself, he keeps repeating the mantra his mother Penny Fleck (Frances Conroy) gave him. She told him you were born to spread joy and laughter. The mantra gives him little to no protection from pain. He repulses others and they project their angst and demons on him. Although treated with medication, his serious mental condition is uncontrolled. At his social worker’s suggestion, he keeps a journal which he punctuates with quips. He has not given up on himself or his dreams. But despite his rotten roots or because of it, he understands kindness, decency and respect for all. In many ways, he is a good person but deeply disturbed. Life is unkind to Arthur as he states, “I just don’t want to feel so bad anymore.” He wishes that his “….death makes more sense than his life.”
Gotham, mythical home of Batman and the Joker, is a metropolis very similar to New York. In this movie, it resembles a 1970s, a period of crime and decay. Arthur lives with his bed-ridden mother. When Arthur’s boss scolds him for bad behavior after he is attacked on the street, a fellow employee gives him a gun to protect himself. He returns to his slum apartment and checks the lobby mail box. When he reaches his floor, he meets an attractive young woman who lives down the hall. Surprisingly, he hits it off with her.
Arthur goes into his apartment. While watching a Fred Astaire movie, he joins in the dancing and joyously fires the gun given to him. Afterwards, he gives his mother a bath. Once again she mentions waiting for a letter requesting help from Thomas Wayne, her former employer. Thomas Wayne is the father of Bruce Wayne whose secret identity is Batman.
Fleck goes to a children’s hospital where he joyously entertains the patients. Taking the subway home, he witnesses three men menacing a young woman. Arthur deflects the men’s attention from the girl so they go for him instead which leads to a confrontation. Arthur returns home dancing along the way. When he reaches his apartment floor, he sees his lovely neighbor again, and they kiss passionately. Mobs gather in Gotham’s streets as Arthur goes to visit his social worker. She tells him that city services cut off medications for the mentally ill.
His mother is hospitalized with a stroke. She mentions to him that Thomas Wayne is his father. He finds that to be untrue but discovers a much darker scenario, and he goes into a rage. Dancing with abandon in the streets, Arthur joins the mob.
Todd Phillips', the writer/director, first film was a documentary about a punk rocker who was a violent drug abuser. This film is the dramatization of his documentary. Prominent themes in The Joker are neglect of the mentally ill and hatred toward the rich. It’s an adult film with gory scenes. Phoenix inhabits his character and scares the hell out of the audience. Although Phoenix’s portrayal is heart stopping, stay away if you would find constant graphic violence disturbing.


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Judy Garland Musical Chasing Rainbows to Hold Private Industry Lab
Jason Danieley, Karen Mason, Max von Essen, and more will lead the cast.
First Look at Michelle Williams and the Cast of Aida at The Muny
Elton John and Tim Rice's Egyptian musical has landed in St. Louis.
Cheers Live on Stage Sets Casting for Touring Production
Everyone will know your name across the country.
Destiny's Child's Michelle Williams to Star in Aida at the Muny
Williams will reprise the role in which she made her Broadway debut.
Drama Desk-Nominated Pageant — The Musical Sets Cast Album Release Date
The off-Broadway cast will reunite for a launch party at 54 Below.
Off-Broadway Musical Hit Pageant to Release Cast Album
Pageant features a book and lyrics by two-time Tony nominee Bill Russell and Frank Kelly, with music by Albert Evans.
Pageant Extends Off-Broadway Run at the Davenport Theatre
Comedian Kevin Meaney leads the cast of this musical revival.

domain: celebrity


Whenever Weezer release a record, their fans brace themselves. Since 2001’s ‘Green Album’, it’s been a case of diminishing returns. Until now. Reunited with The Cars’ Ric Ocasek, who produced that album and their eponymous debut, this ninth full-length is their best in years. Yes, lead single ‘Back To The Shack’ is a postmodern schlock-rock song (ironic considering it’s about returning to their roots) and ‘The British Are Coming’ is intolerable, Darkness-esque cock-rock (no surprise as it’s a Justin Hawkins co-write), but they’ve noticeably toned down the self-aware satire. ‘Foolish Father’, ‘Lonely Girl’, ‘Go Away’ and the three-part suite (yes, really) that closes this record are pretty great too. It’s no ‘Pinkerton’, but Weezer, finally, are back on track.
Weezer – ‘Everything Will Be Alright In The End’
The US band get back on track as they're reunited with old producer


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Have you ever heard the phrase “Don’t worry about it!”? Doesn’t that just make you worry more? Worry is not just something that you can turn off, sometimes you have to learn how to navigate your emotions as they happen. On this adventure, follow Chiko as he remembers the many special times, he has shared with Chubbs and discovers that worry can be overcome.
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domain: psychology


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The eternal struggle of the human circumstance is discovering the purpose of one’s life. We spend countless hours in school, working jobs, or deep in thought attempting to ascertain the reason for our existence. For some, they believe that discovering what they are most passionate about, or that for which they have a particular talent will provide their lives with enough meaning to remain fulfilled. Toward the beginning of Paul Thomas Anderson’s 1997 film, Boogie Nights, Eddie Adams (Mark Wahlberg) says, “Everyone is blessed with one special thing.” Eddie’s belief that he would be a star, that he was destined for greatness led him to a life acting in adult films, making an abundant amount of money and being surrounded by beautiful people. For Eddie, who would adopt the stage name Dirk Diggler at the beginning of his career, this belief in his own star power helped him through the struggles of his life’s difficulties.
A troubled relationship with his mother left Dirk with a home base lacking in love, leading him to find both affection and acceptance in those not related to him. Dirk was fortunate and found a surrogate family of people who had also discovered their talents and each other. Even being surrounded by a group of people who remained committed to the abilities they found within themselves, despite public perception, they are still fallible human beings. In one way or another, each person in Dirk’s substitute family brings about their own downfall, a theme that seems prevalent in my fledgling study of Paul Thomas Anderson’s films.
Jack Horner (Burt Reynolds), an adult filmmaker who discovers Dirk, is reluctant to adapt within the changing world of his profession. At a point in his life where he is preoccupied with his own mortality, Jack is determined to leave behind a legacy. Jack’s determination is grounded in a longing to prove that he existed, and his life was worth living. When he becomes consumed by his desire to create something that would outlast him, Jack neglects those around him who were also seeking fulfillment and made poor decisions putting the lives of those he cherished at risk. Amber Waves, (Julianne Moore) Jack’s leading female film star is a damaged woman devastated by the separation from her son she endures while going through a messy divorce and custody battle with her ex-husband. Desperate to legitimize herself and her career, Amber gives her all to her work but is left empty during the nights and turns to drugs to fill the void in her life. Amber also forms a close bond with Rollergirl (Heather Graham), a young woman who left her life and family behind and found solace with Jack and working in his films. Leaving her family and education behind, Rollergirl often felt alone, notably missing the bond a daughter and mother typically share. Fortunately for Rollergirl, she found such a relationship with Amber, though, she also began using drugs with her. Buck Swope (Don Cheadle), another member of Jack’s employ, feels uncomfortable in his skin when he is away from his fellow adult film workers. Unable to find a place for himself outside of the adult film industry, Buck proves that he will violate his ethical code by stealing to get what he wants out of life. Finally, there is Little Bill (William H. Macy), a crew member who works with Jack on his films.
Perhaps the most interesting character in Boogie Nights, Little Bill created a fascinating character study. Being married to a serial cheater takes its toll on Bill emotionally, especially the lack of remorse his wife shows throughout the many times he caught her with another man. Bill is also clearly conflicted in his work. Bill recognizes that he works in an industry that doesn’t always take sex seriously, as Bill does. Seeing Jack disregard sexual intercourse, at times, and witnessing his wife’s constant sexual exploits against their marriage drives Bill to kill his wife and then himself in a desperate move to escape that which with he cannot cope. Little Bill and Buck Swope share a commonality, they both find themselves at odds with their moral compass and their working life. Buck is using his particular talent to save enough money to achieve his passion, owning and operating his own stereo business. His naivety leaves him surprised when he is unable to secure a loan to start his business because he works in what the bank terms as “pornography.” This realization sends Buck into a tailspin; he feels as though all of his work and compromise was for naught and he fears he will be unable to realize his dream.
The turning point with Buck is when he happens upon an opportunity of sorts, to secure the money for his business. When he happens to be in a donut shop at the time it is robbed, and everyone else in the shop ends up dead, the newly jaded Buck steals the money left behind on the floor. The Buck that existed before he was unfairly denied a loan would have certainly waited for the police to arrive. Often, characters in films are viewed as less than human, and instead projections to be considered differently than ourselves. Paul Thomas Anderson does an exceptional job showing how much people are changed as their relationship or what they know about the world changes, reminding the audience that those depicted in his films are as human as we are.
The endless search for love is beautifully explored throughout Boogie Nights. What we are shown in the film is a collection of characters that are in desperate need of affection. For some, the absence of love brought them into the world of adult filmmaking, for others, it led them to drugs or alcohol to cope with their internal emptiness. A primary tenant of human psychology asserts that we need love to survive, and the characters in Boogie Nights are no different. Paul Thomas Anderson fleshes out this fundamental need for human love in a touching way throughout the film showing both the pursuit and attainment of love. As often is the struggle in life, however, anxieties and feelings of uncertainty arise once someone has attained love or found their talent.
As illustrated in Boogie Nights, the characters often resort to drug use or excessive drinking even after they found their place in the world. These drugs, however, weren’t the reason for each character’s downfall; instead, they were agents used to achieve their destruction. When each character begins using drugs, there is an individual element of self-sabotage being performed, as is often the case with Paul Thomas Anderson’s characters. An event or feeling overwhelms the character, and they then turn to drugs to entirely give into the negative feelings they are experiencing. For instance, inflated by his ego, Dirk walks out during a shoot and tells Jack he quits. Without the security of his surrogate family and the opportunities Jack provides, Dirk realizes that he can never replicate the life he enjoyed. Dirk turns to drugs in what seems like an attempt to reach his rock bottom. Dirk gives in at a point and stops trying to help himself, allowing his emotions to overwhelm his rationality and submitting completely to the drugs.
Many characters in Boogie Nights, in fact, hit a personal rock bottom before returning to their self-professed purpose in life with renewed enthusiasm, validated by their ability to triumph over their trials. The drug use is also depicted as a stand-in for the love they are not getting in their life. Having something to depend on, no matter how damaging it is, provides comfort for some people. Amber is in a state of constant withdrawal of love due to being separated from her son, and her turn to drugs seems to suggest that she felt as though the drugs were what was there for her when she had no one else. The mother-daughter relationship she fostered with Rollergirl, certainly gave her an outlet for her motherly instincts, though the times the pair was closest also involved heavy drug use. Paul Thomas Anderson offers an engrossing narrative on the relationship between drugs and love, or a lack of love, in Boogie Nights, further humanizing the characters within his films.
The hallmark I find most captivating in Paul Thomas Anderson’s films, especially in Boogie Nights, is the examination of ego. In each character’s arc, there can be pinpointed a time where their ego was the driving force of their behaviors. Ego led Dirk astray when he began to believe he was the best star Jack could ever have, demanding a crew of people adjust their lives and schedules around his. When Dirk’s ego clashed with the ego of the other’s on-set, especially Jack’s, conflict erupted. The audience can see Dirk submit to his ego completely, which ultimately brings about his downfall. Jack’s ego led him on the futile quest of attempting to build a legacy and gain recognition beyond the confines of his life. Some people craft their legacies for years throughout their life and career in an attempt to prove that they were here and mattered to the world. Mortality is an uncomfortable issue to face, and the most common reaction, once it is confronted, is fear. Typically, panic sets in as we question the existence of an afterlife while desperately trying to avoid the inevitable circumstance of being forgotten. It is only once this ego is released, however, that we can realize that the real prize of existence are the relationships we enjoy throughout our lives. Ego is an impenetrable barrier to break, even for a force as strong as love, and it is ego that often prevents us from living our true selves, allowing love in. Ego can destroy or deter interpersonal relationships and can halt any success we may enjoy in its tracks. Paul Thomas Anderson not only shows how damaging ego is in Boogie Nights but also shows how easy it is to fall victim to.
The technical mastery on display in Boogie Nights is captivating. From the opening of the film we see an active, always moving, yet incredibly controlled camera. As the title is displayed in neon lights outside of one of the clubs, we follow the camera as it enters the lively atmosphere of the dance club and settles on the star of the film, Mark Wahlberg. Through the dynamic movements, the audience perceives not only the energy of the club and the atmosphere of the world the film will build but also the unsettled mind of the subject. We soon learn that Eddie (Dirk) is unhappy in his life and believes he is destined for better things than his current situation would suggest, and the bit of foreshadowing by Paul Thomas Anderson’s beautifully fluid camera movement acts as a poignant invitation into the mind of his principal character. The film is filled with equally as impressive camera mastery proving Paul Thomas Anderson’s gifts abound both in narrative storytelling and moving imagery. Actors in Paul Thomas Anderson’s films reach a peak in their pairings with him that is extraordinary. I’ve never seen Mark Wahlberg perform better in a role than Boogie Nights; he was brooding, angry, heartwarming, and able to span an emotional range unparalleled through his career.
Seeing the potential in each person he casts and bringing that potential to the characters he’s written adds a profundity to Paul Thomas Anderson’s films that devote audiences to him. Brilliant writing, superb acting, and an immense depth in each of his films provide for the audience a rich cinematic offering. Boogie Nights is so much more than a film about the nameless, moralless caricatures often attributed to people that work in the sex industry. Paul Thomas Anderson humanizes his characters and reminds the audience that no matter what we do and where our talents lie, we all possess a uniquely human perspective. We often need to be reminded of the universal quality of human life, and Paul Thomas Anderson’s films are the perfect vessel to awaken us to our shared human condition.


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Diver Aldridge arrested for shoplifting and assault
Olympic diver Blake Aldridge, who partnered Tom Daley in Beijing, has been arrested on suspicion of shoplifting and attacking a supermarket security guard, police said today.
Aldridge, 27, has been bailed to mid-March pending further inquiries into the incident in the early hours of Friday at the Tesco in Croydon Road, Beckenham, south east London.
Police were alerted to calls of a "shoplifter causing a disturbance" at 2.30am, Scotland Yard said.
A 27-year-old man was arrested on suspicion of causing actual bodily harm to a male security guard and shoplifting bottles of wine.
The other alleged suspect had already left by the time officers arrived at the store, police said.
Aldridge and Daley came eighth in the 10-metre synchronised dive at the 2008 Olympics.
Aldridge made a mobile phone call midway through the final and then blamed Daley's nerves for the pair's placing.
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domain: law


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In Sandra Cisneros' novella, "The House on Mango Street," a thirteen year old girl named Esperanza takes the audience through a series of events as if they are living Esperanza's life with her. Cisneros vividly describes the many troubles Esperanza faces in 1970's Chicago. All the families that live on Mango Street are poverty stricken and Esperanza hopes to one day leave Mango Street to become successful. Women in the 1970's were not treated equally to men, they were abused and dominated in society. The men of Mango street beat the women and control every aspect of their lives. The women in the book are tied to the men, as they directly or indirectly try to escape their lives on Mango Street and try to find a better future for themselves which is also why the book is dedicated "to the women." Cisneros believes that the key to freedom for the women is education which can bring them success.
Most the men in the novella treat the women badly. "He never hits hard" (Cisneros 92). This portrays that the women of Mango Street are so scared of the men that they try to cover up and justify the abuse. The men misuse their strength in the family, as well as physical strength to control the lives of the females. Since Sally's father makes the money for the family, he has all the power and until Sally can complete her education she will never able to gain control of her own life. .
The only exception to the brash, uncaring and almost disgusting men of Mango Street appears to be Esperanza's father in cries in the book, jokes with Esperanza, does not physically harm his wife or kids and works hard. "My brave Papa cries.I have never seen my Papa cry" (Cisneros 56). Cisneros uses Papa as a foil character to all the other men on Mango Street. He is the only positive male role model throughout the entire novella. Even though he has an education and brings the income in for the family, he does not abuse the power he possesses.


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It’s hard enough to teach our kids to avoid drugs when even popular celebrities and members of Congress, not to mention the cannabis industry, are trying to normalize its use.
Informed Families Blog
When it comes to addiction, a lot of young people think it can’t happen to them. But it can, and it does. Especially with a drug like Xanax.
Too many people think that illegal drug use and drug overdose deaths can only happen to other people’s kids. Or to “losers” who come from a “bad” background.
Topics: safe homes smart parties
While the Media Was Focused on Opioids Look What Happened
While the media has been focused on the opioid crisis, the number of alcohol-related deaths more than doubled from 35,914 in 1999 to 72,558 in 2017. Women have been impacted the most.
According Dr. George F. Koob, National Institute on Alcohol Abuse and Alcoholism (NIAAA) Director, “alcohol is a growing women’s health issue. The rapid increase in deaths involving alcohol among women is troubling and parallels the increases in alcohol consumption among women over the past few decades.”
Trends like Mommy wine culture, which normalizes the idea of drinking alcohol as a way to cope with stress, and sipping while shopping have become commonplace. We should always keep in mind that our kids are watching our behaviors. Do we want them to turn to alcohol as a way to escape from everyday stress or as the only way to relax and unwind?
They are bombarded with images promoting alcohol in that way already. A new report from the Journal of Studies on Alcohol and Drugs says alcohol ads are leading teens to drink. A study in the Preventive Medicine journal found that social media could be sending out positive messaging about alcohol use as well.
Sign the Safe Homes Smart Parents pledge, and let’s work together to stem the tide of alcohol-related deaths by discouraging underage and binge drinking.
“I learned how to handle peer pressure and say no to drugs.”
“I didn’t know people could die from alcohol poisoning.”
“I didn’t know how much of a problem prescription drug abuse was.”
“Many of our peers are dealing with drug issues themselves or have a family member with a problem.”
Student ambassadors in the Miami-Dade County Public Schools Creating Community Change: Youth Engagement Program (CCC:YEP) program shared these messages and much more during their end of the year presentations at the Betty T. Ferguson Center in Miami Gardens on May 22, 23 and 24.
Topics: red ribbon week, ambassadors, prescription drug abuse, lock your meds, safe homes smart parties, middle school, peer pressure, drug free, drug prevention, parent peer group, miami gardens, miami
Communicating Across Generations
I recently read that some families now have five living generations. Imagine that. Each generation has a totally different world view and processes information in a different way. However simply engaging with others remains the key to communicating effectively.
It's Time For A Duel With JUUL
As our Safe Homes Smart Parents campaign kicks off, we think about all of the unhealthy trends facing our youth and what parents can do to protect their children. Right now, we are fired up about the 78% increase in e-cigarette use among high school students, as a result of JUUL Labs’ targeting of our youth. According to the U.S. Surgeon General, last year, 3.6 million U.S. youth use e-cigarettes. Talk to any teacher or parent of a teen and they will confirm the schools are overrun by JUUL and kids are showing real signs of addiction.
Some lucky ones will put away their JUULs before they’re addicted. But many are embarking on a lifelong addiction to nicotine. Many of those will continue to use JUUL for a considerable amount of time, and we simply do not know what consequences long-term use will have on their health.
What we do know is that e-cigarettes are not safe. And we know that nicotine use by children and teens negatively impacts their brain development. Among other things, it makes them more susceptible to addiction in general. The larger fear is they switch entirely to cigarettes and other tobacco products that are even more dangerous.
5 Steps To Creating A Happy & Healthy Family In 2019
Have you seen Informed Families’ Lock Your Meds signs at your local Publix Pharmacy store? Through our amazing partnership with Publix Pharmacy, we are reaching roughly 1.2 million people in 720 stores across Florida and 397 in the Southeastern US with the Lock Your Meds message. Wow!
A happy and healthy family starts when you create a safe and healthy environment for children. This includes securing your medication, taking regular inventory to ensure nothing is missing and safely disposing of unused or expired medication.
Also, keep tabs on your liquor cabinet - and resist unhealthy social norms that make you feel bad for not “teaching your child to drink” at home. The research shows that children who start drinking before age 15 are 5 times more likely to have alcohol problems at adults.
WHAT IS AMERICA'S ALCOHOL AWARENESS?
April is Alcohol Awareness Month, so let’s talk about alcohol.
Parents are still the number one reason kids give for not using alcohol and drugs.
Parenting is a hard job. You rarely get thanked and pushing back against unhealthy behaviors is hard. We know you want the best for your kids – and when you know better, you do better.
Americans are more into using alcohol – and less into understanding alcohol’s negative effects, considering that:
- Alcohol is a carcinogen and is linked to cancer. In fact, alcohol is responsible for an estimated 15 percent of US breast cancer cases (35,000/year) and deaths (6,600/year).
- Underage drinking causes 4,300 deaths and 189,000 emergency room visit per year and
- Alcohol damages our stem cells.
- People who consume more than one drink a day are more likely to die earlier and have greater health problems.
SAFE HOMES SMART PARENTS
Last week, we had an amazing conference call with one of our absolutely favorite Ambassadors, Tracy Bowen, of Collier County Public Schools. Tracy said that our Safe Homes Smart Parties campaign should be renamed the Safe Homes Smart Parents campaign because Safe Parties Require Smart Parents. Parents are the key to safe children.
She hit the nail on the head and we are taking her advice very seriously and determining what that change means for our campaign. The best ideas come from boots on the ground and Tracy is a wonderful example of someone using her knowledge, experience and passion to help the children in her community grow up safe, healthy and drug free.
It’s been 36 years since we founded Informed Families and I’m still simultaneously confident that our prevention programs will help students make good choices this Spring Break and fearful that some parents are misinformed about the dangers of underage drinking, thus choosing to host parties and expose children to potentially frightening consequences. Social norms about alcohol are overwhelming to a parent’s better judgment. How can we help each and every parent take a stand for Safe Parties?


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Friday, March 6th
This class will be a 4 course meal made up of our favorite recipes. You'll learn techniques that you can apply at home when entertaining family and friends. We'll show you how to make a great Beurre Blanc, properly pan sear a scallop, and plating techniques. We'll have a variety of wines for you as well.
Pan Seared Scallops with Crispy Prosciutto and Chive Beurre Blanc
Leek and Bacon Crostini with Goat Cheese
Classic Caesar Salad with Sourdough Croutons
Grilled Ribeye Steaks served with a Swiss Chard and Gruyere Gratin, and Cabernet Demi Glace
Apple Crostata with Salted Caramel Ice Cream
$175 per couple

domain: food


Buffalo, New York Police Commissioner Daniel Derenda is sending officers out to look for guns following funerals. (Photo: Buffalo News)
Buffalo, New York police are now visiting the homes of those recently departed in search of firearms as part of a new plan to help keep tabs on local guns.
The move, put into effect by Police Commissioner Daniel Derenda, is described as an effort to stop firearms, specifically handguns, from winding up back in circulation and off the books.
“We recently started a program where we’re cross referencing all the pistol permit holders with the death records, and we’re sending people out to collect the guns whenever possible so that they don’t end up in the wrong hands,” Derenda told WGRZ. “Because at times they lay out there and the family is not aware of them and they end up just out on the street.”
City code forbids disposing of a firearm unless it is to a gunsmith or licensed firearms dealer or as part of a testamentary bequest such as directed by a will. However, these guns can be voluntarily surrendered.
The BPD has long been involved in efforts to take guns out of circulation through a variety of means. This summer, a long-running gun buyback program netted some 840 firearms in its latest installment. It was the second-highest number recovered on record by the agency. While many gun rights advocates have long held these types of buybacks do little to stop crime, Buffalo officials argue that it is still beneficial.
“If they’re working, if they’re lethal, if they’re unwanted, we need to get them out of the homes,” said Buffalo Mayor Byron Brown (D) of the buyback program, now in its seventh year. “What we have found is that law abiding citizens have had their homes burglarized, guns that were legal end up on the street being used in crimes.”
However the police department’s zealousness to fight crime has brought the recent attention of federal investigators. which led to the indictment of three current and former officers this May on civil rights violations. These allegations included officers shooting handcuffed teenaged suspects with a BB guns in a case of excessive force.
“There is a culture within the Buffalo Police Department that is not easy to change,” FBI Agent-in-Charge Brian P. Boetig added when discussing the indictment and other recent acts by BPD officers in the public light.
Guns.com reached out for comment to the Erie County Clerk’s Office Pistol Unit, which issues handgun permits for the Buffalo area as well as the Buffalo Police Department itself without success.


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Strengthen mental-health and build imagination with over 100 hours of non-digital, distraction-free entertainment. Köpialine drawing books are a captivating, self-guided activity that keeps kids engaged in the creative process for hours on end.
From contemplating cats to derpy dinosaurs to distinguished detectives, every page is thoughtfully designed to stoke a youngsters enthusiasm for drawing.
“The lines are gonebut will return,immerse yourselfand you will learn.”
Kopiography is the foundation upon which every Köpialine image is built.
It’s defined as the art of using shapes as drawing-guides and it provides an opportunity for everyone to experience the joy of drawing without becoming discouraged by overwhelm, confusion, and information overload.
The best conversational language-learning programs (like Pimsleur & Rosetta Stone) use repetition, context, and immersion to help you speak, understand, and read new languages quickly and easily.
At the core of Köpialine, you’ll find a similar system that revolves around these same three pillars while you learn the language of shapes.
“Tell me and I forget. Teach me and I remember. Involve me and I learn.” ~ Benjamin Franklin
To many, especially those who are just starting, step-based, how-to-draw methods can be intimidating, overwhelming and frustrating. More often than not, this leads to discouragement and giving up.
Conversely, Kopiography weaves familiar, basic shapes within the context of fun imagery, making the act of drawing enjoyable & accessible for everyone.
Kopiography removes the process of conceptualizing form, shape, depth, size, color, and perspective. You are left merely with the task of line placement.
To the amateur, Kopiography makes drawing much more approachable.
Even the simplest of Kopiographic images are designed to hold your attention and challenge your cognitive control of movement.
As a child, your first spoken words were the direct result of you experiencing the world around you. Ultimately, you learned how to talk by copying the sounds you were hearing and you learned what to say because of context.
Kopiography uses an immersion-based learning method to place you directly into the experience of drawing. It empowers you with a feeling of confidence while drawing and can help lay the foundation for more advanced study.
Kopiography gets you drawing meaningful images with a satisfying outcome – right from the start.
Kopiographic images are thoughtfully constructed using a collection of closed shapes.
Many of these closed shapes are repeated periodically throughout different pages, often ‘hidden in plain sight’.
As you work your way through a series of drawings, you’ll intuitively begin to expand your shape vocabulary, build muscle-memory, and gain an understanding of how similar shapes can communicate different ideas based on context.
Looking at different Kopiographic pages, you’ll begin to understand how one simple shape can communicate a wide variety of different expressions, depending on context.
‘We wanted to make the colouring book of drawing books!
Our first Kopiography book makes drawing so easy and accessible that even someone who “only draws stick figures” can pick up a pencil and experience the same joy I feel as a seasoned illustrator.’ ~ David Shearer
Designed to be a guided sketchbook, the first-ever Köpialine book uses Kopiography to help enable even the most amateur of artists to draw confidently, perhaps even for the first time!