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By Sandra Gibson Hassink MD
This convenient, useful consultant offers clinicians with a complete method of the scientific administration of obese youngsters and teens. insurance starts off with the epidemiology, pathophysiology, and developmental points of kid and adolescent weight problems and a advisor to overview of overweight little ones. next chapters deal with breathing, cardiovascular, endocrine, metabolic, orthopaedic, gastrointestinal, renal, and neurologic issues and comorbid stipulations in addition to psychological well-being matters, acute obesity-related emergencies, and weight problems as a part of genetic syndromes. Pathophysiology is associated with medical presentation, evaluate, and remedy, and way of life matters are mentioned the place applicable. Highlighted packing containers and algorithms aid clinicians locate and digest info quickly.
Read Online or Download A clinical guide to pediatric weight management and obesity PDF
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This useful, sensible advisor offers clinicians with a finished method of the scientific administration of obese young ones and youth. assurance starts with the epidemiology, pathophysiology, and developmental features of kid and adolescent weight problems and a consultant to evaluate of overweight young ones.
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Extra info for A clinical guide to pediatric weight management and obesity
1999;282:1561–1567. 29. Burdette HL, Whitaker RC, Kahn RS, Harvey-Berino J. Association of maternal obesity and depressive symptoms with television-viewing time in low-income preschool children. Arch Pediatr Adolesc Med. 2003;157:894–899. 5592_LWW_Ch05pp039-050 9/22/06 7:34 AM Page 39 5 Evaluation of the Obese Child GROWTH The first step in the evaluation of the obese child or adolescent is determining the height and weight and calculating the body mass index (BMI) (1). S. population collected between 1963 and 1980.
N Engl J Med. 1997;337:869–873. 13. de Graaf C, Blom WA Smeets PA, stafleu A, Hendriks HF. Biomarkers of satiation and satiety. Am J Clin Nutr. 2004;79:946–961. 14. Blundell JE, Lawton CL, Cotton JR, Macdiamid JI. Control of human appetite: implications for the intake of dietary fat. Annu Rev Nutr. 1996;16:285–319. 15. de Graaf C, DeJong LS, Lambers AC. Palatability affects satiation but not satiety. Physiol Behav. 1999;66(4):681–688. 16. Tordorff MG. Obesity by choice the powerful influence of nutrient availability on nutrient intake.
Fetal and infant growth and impaired glucose tolerance at age 64. BMJ. 1991;30:1019–1022. 3. Law CM, Barker DJ, Osmond C, Fall CH, Simmonds SJ . Early growth and abdominal fatness in adult life. J Epidemiol Community Health. 1992;46(3):184–186. 4. McMillen IC, Robinson JS. Developmental origins of the metabolic syndrome: predication, plasticity, programming. Physiol Rev. 2005;85(2):571–633. 5. Toschke AM, Montgomery SM, Pfeiffer U, von Kries R. Early intrauterine exposure to tobaccoinhaled products and obesity.
A clinical guide to pediatric weight management and obesity by Sandra Gibson Hassink MD

domain: health


Sutli Winder Machine is high in demand in industries for winding all types of PP strings and threads. These machines are offered to clients in a wide range of specifications and configurations in order to meet their diverse requirements.
Unlike other conventional machines, our winding machine is integrated with a uniquely designed unwinder that makes optimal use of any leftover yarn which in turn reduces the cost product. In addition to this, it is also installed with a heavy duty motor for assuring good performance under extreme conditions. The machine also features a user friendly interface which enables easy and smooth functioning of the machine along with easy adjustments.
As per the needs and requirements of our clients, we are involved in manufacturing and exporting sutli cheese winder machine. Using quality approved components and innovative technology, the provided plant is assembled under the supervision of deft engineers. To eliminate any kind of defect, this plant is rigorously tested on diverse measures of quality in adherence to predefined industry standards and norms. This plant is highly acclaimed in the market for its hassle free performance and functionality.


As you may or may not know, I had the wonderful pleasure of going to Glastonbury 2019 about 2 weekends ago now and had the time of my life. As a huge lover of live music, being able to go from set to set of such great artists was one of the best experiences ever.
In this post, I’m listing my 6 favourite artists that I had the pleasure of going to watch over the weekend. There were hundreds of acts playing all weekend and all together my boyfriend and I went to see around 25. But, this post today is basically my highlights reel from my 3 days at the festival.
Maggie has to be the first artist on this list seeing as I almost cried happy tears during her set. She has such an open and beautiful presence on stage and seeing her live was kind of unbelievable for me as I’ve loved her and her music for so long.
Her album, Heared it in a Past Life, has basically been on repeat since its release, and so to hear Maggie perform it live was an absolute dream, especially when she performed it as well as she did. Maggie’s way with music has always inspired me and is a big part of why I became a fan. The way she’s so free on stage and enjoys ebvery beat of music is so beautiful to watch too. So, if you haven’t yet listen to Maggie and her music, I thoroughly recommend.
You can read more about my love for Maggie here in a post I wrote two months ago.
Walking over to Stormzy’s set, I vividly remember thinking that I won’t last the full 1.5 hours, just because I only knew about 5 of his songs. But, in saying that, his set was by far the most surprising. I think, because I wasn’t expecting to enjoy it as much as other artists, it actually ended up blowing me away and I was pleasantly surprised as to how much I enjoyed it.
He was very proud, passionate and political throughout his time on the Pyramid Stage and really used his platform to be able to shoutout up and coming grime artists, pay homage to the artists that paved the way for him and to also celebrate black excellence in the music industry by only having a black ensemble supporting him. This included backing dancers, choirs, and special guests. The only white person that ever came on that stage with him was Coldplay’s Chris Martin.
It was obvious how much thought and love Stormzy had put in to creating and delivering his headlining performance and what really blew me away was how humble and appreciative he was of it all. I will remember this set for a long time to come.
I managed to get front row for Sigrid as, just like Maggie, she was one of the top artists that I really wanted to see live. As soon as she came out you could see the excitement and readiness to enjoy in her face and she absoloutley delivered!
I’ve watched her live sets online before and I think it was that energy that I’d always wanted to experience. Her presence on stage is so fun but still manages to make a genuine connection between her and the crowd, which I think is super important. It was obvious that Sigrid properly loves the music that she’s put out in the world, because if she didn’t, she definitely wouldn’t have put on the show that she did.
Another aspect that I appreciated, that I don’t see very often, was that she brought her backing singer and guitarist down for a song and the musical and emotional connection between them was so wonderful to witness. I really love it when artists appreciate the people around them, whether that’s fans or their band, it makes them so much more than the music they create. You get to see them as a person enjoying what they’re doing rather than your favourite artist, and I can’t wait to be able to see Sigrid live again, whenever that may be!
I’m not sure if many of you would have heard or know of Dermot Kennedy. He’s an Irish singer songwriter who has one of the best voices I’ve heard in a long time. I went to his set knowing all of 2 songs and went to get away from the boiling sun, as he was playing in one of the tents. But as soon as he came on stage and started to sing, he genuinely made my choice of going to see him extremely worth while.
I hadn’t heard many of these songs until he sung them on that stage, and after every song finished I turned to my boyfriend and was constantly complementing his voice and music abilities. And what’s really nice is that he doesn’t loose his Irish accent whenever he sings.
He is a star in the making and I’m sure we will all be bowing down to his beautiful voice in the near future.
What. A. Show.
The Killers were by far the most entertaining act of the festival. Brandon Flowers is one of the geatsest front men that I have ever had the privalidge to see live. He gave everything he had into this set and that was clear to see. His face radiated happiness and positivity and definitely spread into the massive crowd that was watching him.
Along with that, The Killers as a band absolutely smashed it and Ronnie Vannucci (Drummer) was a beast behing the drums. I remember my boyfriend constantly shouting in awe of how good he was.
But, what really made it for me was being stood in one of the biggest crowds I’d ever been a part of, singing some of the most iconic songs from my childhood! I feel like the memory of screaming “Mr Brightside” and “Human” with tens of thousands of people will always be as vivid as the moment I witnessed it.
Christine and the Queens
I am absolutely in love with Chris. Her set was incredible. She had honestly produced what felt like a mini West End production. Her choreography beautifully complemented her music, and I’m pretty sure she had the whole crowd mesmerised from the start.
She has such versatility in her songs that the crowd would be dancing around one minute and holding onto each other with love the next. She has a very powerful presence and I think that that’s down to how happy and content she is within her self and her self-expression. I found her extremely empowering to watch. It really inspired me seeing a woman so happy whilst being so non-conforming to what a stereotypical woman should be. Chris really is amazing.
And what was even better was that she, just like Stormzy, used her platform and presence to educate and inform all whilst having the time of her life. I remember as soon as her second song finished playing she silenced the crowd just so she could say something along the lines of “this space here, that we’re in right now, is a safe place. A happy place. A place where we can all be free” and it genuinely resonated with me so much. It was truly the most powerful moment I have ever witnessed at a live show.
Hopefully you guys have enjoyed this post and let it maybe spark an interest to go to Glastonbury in future years! The variety and scale of the live music available is like nowhere else in the world and to experience that is so cool!
I also just wanted to say thank you for being so patient with me. I have had time off for a while now but only because I have been away and celebrating, which is why the Glastonbury post is going up about 2 weeks after I actually went.
I’m hoping to get my next and final Glastonbury post up this weekend, and it’s all about my Glastonbury fashion! What I wore, by who, and how much it all cost. I will hopefully see you all again then.
Thanks again for reading,


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The Ernest and Marjorie Fudge Trust for Warminster has generously agreed to support the work of Open Door with a wonderful grant. The money will be used to secure the running of the twice-monthly Grief Group for the whole of 2024. The grief group supports anyone affected by a change in their life that has triggered feelings of loss and grief.
Open Door is entirely grant-funded so every donation is appreciated and put to good use for the community of Warminster.
Our grateful thanks go to the Trustees of the Fudge Trust for their belief and support for our work.

domain: finance


|Perhaps the best product|
|…you’ve never seen|
|When we first heard the name “Clear Bra,” visions of the latest Victoria’s Secret designs ran through our heads. We knew we had to investigate, strictly in journalistic pursuit, of course. It turns out that Clear Bra is one of the street names for 3M’s Paint Protection Film. Initially developed to guard the leading edges of military helicopter blades from debris, the film has been refined and repackaged for OEM and aftermarket automotive applications.
Clear Bra is a nearly invisible, “always-on” alternative to bulky and often problematic vinyl front-end protectors. You have to be close to the vehicle, and look hard, to spot this stuff. As with vinyl bras, it offers protection from stone chips, insects, small scratches, and the wear-end-tear sand-blasting effect from years of driving.
Instead of having to remove and reinstall a bra after every foul-weather encounter (which can trap dirt and moisture underneath), paint-protection film is semi-permanently installed, similarly to window tint. It has a lifespan of about seven years and requires no special maintenance. Should the need arise, or when the film wears out, it can be replaced. And you can wax it along with the rest of your car, minimizing bug and sap stains and easing stain removal. The only minor downsides are that it’s much less reflective than paint and looks dull under certain light.
The film is supplied in 8 – 14 mil thickness in bulk roll form – for cut-to-fit applications on hoods, fenders, bumpers, mirrors, rocker panels, and lights – or in precut customized application kits for a wide variety of cars and trucks. Installation of the pre-cut kits can be accomplished by a skilled do-it-yourselfer, but professional application is recommended for best results.
Our professional applicator, Hugh Bernardi Jr., of Interwest Distribution Company, demonstrated firsthand what’s involved in the installation process. Hugh used the 14-mil film for all lighting surfaces and 8-mil everywhere else. He cut a nine-foot-seven-inch piece of film, secured one end to the front fascia, and then grabbed the unsecured end, while using the tire as a foot stop so he could lean back and stretch the film across the front of the car. Impressive, to say the least. Vehicles with pronounced bodywork curvature only complicate the job. While the material can be installed on paint surfaces of any age, it makes sense to do the application when a vehicle is new and undamaged. Many dealers provide or subcontract this service.
We’re impressed with Clear Bra. Installation on our SVT Focus came in at about $900, which included covering the hood, fender, mirrors, front fascia, and all front-end-lighting. Prices vary depending on vehicle size and difficulty of installation. Basic hood/fender/mirrors packages, the most commonly purchased combo, cost about $300 installed. Cost of the process compares favorably to that of even the most minor body-damage repair. Clear Bra may even offer a good return on investment for those who lease their cars, as compared with possible paint touch-up costs or reduced vehicle value (most lessors deduct for damage and excessive wear and tear) at lease turn-in.
Wonder if you can buy this stuff through the Victoria’s Secret catalog?


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by Dulles Moms | July 11, 2017 8:23 am
Calendar > Cooking Classes & Events for Kids, ‘Tweens, & Teens
Wegmans is already our favorite place to shop, grab lunch, and at many locations, enjoy a free movie on Friday nights! It’s also the perfect place to enjoy low-cost, hands-on cooking classes. Plus, Wegmans doesn’t skimp on fresh, healthy ingredients that get the kids excited about cooking and trying new foods! Register for each event at the Service Desk. Most events are 1 hour, for children 4 and older, and $10 or less!
Ready. Set. Party!
July 12 & 13, 2017 | Alexandria, VA
This fun, hands-on class is all about new twists on summer favorites. Your kids will be enjoying tasty wraps, slicing up a cucumber blueberry salad, and creating a fruity summer punch – perfect backyard party foods!
Make, Mash, & Flip for Ice Cream!
July 25, 2017 | Fairfax, VA
July 26 & 27, 2017 | Alexandria, VA
Making ice cream from scratch is the start of this fun class! They’ll mash their fresh-made ice cream between cookies to make ice cream sandwiches, then “flip” it by using it as a topper for a fruit-based sundae. Once the kids learn how to make ice cream, they will be cool all summer long.
Scoop & Spin Veggie Fun!
August 9 & 10, 2017 | Alexandria, VA
Make veggies fun and kids will eat more of them! First, your children will love scooping, chopping, mixing, and filling their scrumptious squash boats. And wait until they make and enjoy the tasty tri-color veggie noodle salad!
August 23 & 24, 2017 | Alexandria, VA
This jam-packed class has your junior chefs making Breakfast Tortillas with Jack Cheese (made burrito-style) and Organic Greek Yogurt Smoothies.
Disclaimer/Terms: These opportunities are subject to last minute cancellations and changes that might not be reflected in this DullesMoms.com post. Please, always confirm by calling/clicking.
Source URL: http://dullesmoms.com/wegmans-cooking/
Copyright ©2017 DullesMoms.com unless otherwise noted.

domain: food


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We love Senior Pets! Senior pets have special needs, and benefit from more regular veterinary visits compared to their younger counterparts.
- Dental Disease
- Heart Disease
- Liver Disease
- Kidney Disease
- Endocrine Disorders
- Thyroid disease
These conditions will start to become more prevalent as your pet gets older and as long as they are caught soon enough, can be treated well. For this reason, we recommend twice-yearly veterinary visits for pets over 7 years of age. Your aging pet may be showing early signs of osteoarthritis such as stiffness after rest or play, difficulty going up or down stairs and reduced activity. Early intervention with joint supplements and prescription arthritis medications when indicated, along with modified nutrition and exercise plans, can greatly improve your pet’s comfort and mobility. Likewise, performing annual screening lab work on your older pet can help identify early stages of medical problems that might go unrecognized, and progress significantly without treatment.
Some of our services that are most often used to benefit senior pets include:
- Chronic Pain Management
- Laser Therapy
- Senior Pet Dental Care & Cleaning
Some pets experience age-related behavioral changes that can be a sign of cognitive dysfunction, which is similar in some ways to dementia. Your veterinarian can recommend diet modification and supplements to help improve your older pet’s mental sharpness. Getting older doesn’t have to be fraught with troubles for your pet… see your vet regularly to help keep your senior pet healthy and comfortable.
At Green Cove Animal Hospital, our veterinarians don’t just see your pet’s symptoms as “because they’re old.” Rather, we want to provide your pet with the necessary care to give them the best quality of life for as long as possible.

domain: medical


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A young teenager ditches school on Yom Hazikaron -Israel memorial day.
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Out in the Dark
And Then She Arrived
When Heroes Fly
A Place in Heaven
Freshen up your watchlist with Prime Video’s latest roster of streaming movies and TV shows, featuring some great throwbacks and top-notch newcomers.
See the full list

domain: entertainment


The field of biochemistry is currently faced with the enormous challenge of assigning functional significance to more than thirty thousand predicted protein products encoded by the human genome. In order to accomplish this daunting task, methods will be required that facilitate the global analysis of proteins in complex biological systems. Recently, methods have been described for simultaneously monitoring the activity of multiple enzymes in crude proteomes based on their reactivity with tagged chemical probes. These activity based probes (ABPs) have used either radiochemical or biotin/avidin-based detection methods to allow consolidated visualization of numerous enzyme activities. Here we report the synthesis and evaluation of fluorescent activity based probes for the serine hydrolase super-family of enzymes. The fluorescent methods detailed herein provide superior throughput, sensitivity, and quantitative accuracy when compared to previously described ABPs, and provide a straight-forward platform for high-throughput proteome analysis.


Top Open Source Home Automation Software
The advantages of open source software are numerous, and it’s encouraging to see so many home automation platforms providing completely free and functional software to Internet of Things enthusiasts all over the world. The creators of these home automation platforms have worked hard to create a solid codebase from which you can build your own solution, but is open source good enough? Is it able to achieve its “open” goal, or is it falling short?
A good solution, like most other software platforms, requires a strong community to support and improve it. That’s why we’ve compiled a whopping open source home automation platforms that we think are most interesting in the landscape of IoT.
The platforms aren’t ranked by popularity or market share. They’re arranged in a way that allows us to tell a story about the communities that support these platforms and why having a solid foundation is so vital when picking an open source solution. We have no preference for any of the platforms.
- OpenHAB – empowering the smart home
- Home Assistant – Awaken your home
- Jeedom – Innovative Home Automation
- ioBroker – Automate your life
- AGO Control
We can’t begin this list without mentioning openHAB, one of the open source community’s most powerful actors. OpenHAB is constantly expanding upon its initial offering, with nearly half a million postings on its forums and 33,000 users. Over 1500 devices from Sony, Pioneer, LG, Samsung, and other manufacturers are compatible with the platform. openHAB is open-source software that may be downloaded locally and used on any operating system. Cloud servers are unnecessary.
Home Assistant is a strong player in the open source home automation ecosystem, with a platform that prioritizes local control and privacy over anything else. Home Assistant is similar to openHAB in that it has a similar objective of integrating as many devices as possible into a single free-to-use platform. Home Assistant is perhaps the most adaptable of all the platforms for developers, so you should give it a shot.
OpenMotics takes an unusual approach to open source. OpenMotics offers unique modules designed exclusively for their software suite in order to make their solution as smooth and practical as feasible. For convenience, these can be purchased through their online store, but they can also be entirely replicated using the original schematics and bill of materials. Sure, it’s not as simple as picking up an Arduino or a Raspberry Pi, but we believe it’s a fantastic idea to think about.
Jeedom is a fantastic home automation alternative that is limited by its language. The majority of the Jeedom community is French, and even though the website is in English, the community guidelines and forums are all in French. Jeedom provides documentation in a variety of languages, including English, Spanish, and German. However, compared to home automation platforms like openHAB and Home Assistant, it may be more difficult to grasp.
ioBroker first arrived on the open source home automation scene in early 2017, but it quickly became one of the game’s fastest growing communities. ioBroker is a solid proposition that offers approximately 300 integrations and has over 21,000 users ready to contribute. That’s fantastic, especially because the software is entirely free.
AGO Control is a simple open source dashboard that lets you control and automate your devices more quickly than any other platform. Its simplicity is its strength. AGO Control is a home automation framework that allows you to link anything inside and outside the house. The protocol’s minimal weight makes it readable by both machines and humans… Nice!
Domoticz is difficult to dislike because it provides all you require without asking for much in return. You may get step-by-step instructions for installing and applying the software on their website. Better yet, the community is really active! There are numerous blogs on how to use plugins and devices at the time of writing this article. This is exactly what an open source platform like Domoticz requires, and it’s the ideal learning aid for students.
In the realm of home automation, FHEM is well-known. It’s an open source (GPL) perl server for automating typical household operations like turning on and off lights, adjusting heating, and more. FHEM supports the majority of home automation protocols, and the documentation is excellent… if you can locate what you’re looking for. FHEM is still a decent alternative for aficionados, despite its clumsy interface and the occasional appearance of German.
Calaos, another French player, is an open source home automation platform with a sizable community behind it. The forum isn’t as busy as Domoticz’s, but it’s adequate for learning more about the software’s features. Calaos is intriguing since it provides a whole suite of programmes that can be used on a variety of platforms, including the web, Android, iOS, Linux, and more. The manual also shows you how to set up everything yourself.
Pimatic is a hardware-independent home automation framework that can be expanded with over 70 plugins. Pimatic, like many other frameworks in this field, is based on Node.js. This framework’s main aim is flexibility: it can be picked up quickly and “easy.” You can quickly automate chores by connecting your home gadgets and setting conditional conditions thanks to the built-in functionality.
Homebridge is a NodeJS server that mimics the iOS HomeKit API. This implies that once installed on a low-power machine (such as the Raspberry Pi), it will be able to handle the same Siri requests as your iOS device. Because of the innumerable gadgets that couldn’t connect to the Apple ecosystem, the original contributors to this project came up with the idea of combining the best of both home automation and open source initiatives.
It’s a group effort. Smarthomatic is how Uwe Freese describes it. Uwe created the framework after years of personal and professional experience with microcontrollers. He began putting many of the ideas he acquired on a daily basis together because he was so close to the field of home automation. And, while it isn’t the most comprehensive platform available, this open source solution is intriguing because it was designed particularly for home tasks rather than anything else.
Many people in the community utilise EventGhost, a popular home automation tool for Windows, to automate simple chores. You can establish so-called sets of tasks, which are similar to automation tracks that your devices follow, using this simple framework. Want to use an Xbox controller to open your garage door? Please proceed. We were astounded to discover how active the community is.
MyController is an open source server that allows you to control home or office devices using limited resources (first generation Raspberry Pi and other low-performance boards). Because MyController is so small, it can fit on almost any device and is a versatile solution for hackers. Because the platform is built on Java, it can only be used on operating systems that support it. Unfortunately, the functionality as well as the community are both outdated.
PiDome is home automation software created exclusively for the Raspberry Pi, as the name suggests. The platform offers a fair balance of advanced functionality for power users and a beginner-style dashboard to enable individuals new to home automation understand the various concepts. PiDome is being rewritten at the moment, and the current version is a little obsolete.
The market for home automation servers is huge. HomeGenie is another another open source platform that claims to provide one of the best user experiences available. HomeGenie is an intriguing offer, with a full web-based dashboard and a few integrations to work with. Is there, however, a strong enough community to back it up? Unfortunately, it appears that this is not the case. There are no forums or other locations where users can come together and exchange their knowledge on the software package.


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Mean DAO turns one 🥳
- Today is our 1st anniversary, and we welcome year 2 of the journey.
- We look back to a year of phenomenal growth and progress
- We look forward to lots of new milestones and plans to bring DeFi to everyone
We cannot believe it’s been one year since we first showed the world MeanFi on the Solana Mainnet. We tweeted this back then:
Mean DAO was founded on Sept 17th, 2021, by a small group of friends, software entrepreneurs, and cryptocurrency investors. We came together with the idea to launch a community-owned protocol DAO that could power building the products and infrastructure to become financial equalizers to people and businesses worldwide. We are firm believers in the future of DAOs for shared ownership and the value created when an ecosystem collaborates to build vs. compete.
Back then, our small team of five had been working tirelessly to bring MeanFi to life, with less than 20 people helping us with feedback in devnet and testnet. We didn’t even have our RPC infrastructure and used the public Solana RPC! 👀 OMG! 🤦
But our message of simple DeFi banking for everyone powered by payment streaming real-time finance resonated with so many people that it took only a few days after launch for our new protocol to go ballistic. Now, a year later, after many mistakes, learnings, surviving the bulls and the bears, the rug-pulls and liquidations of Terra and 3AC, the dramatic monetary policy changes, the many product releases, partnerships, and crypto markets rollercoasters, we are very ready to take on the next 12 months.
We did a lot of planning and had a busy and ambitious roadmap. We won most of our essential battles and underestimated the efforts of others. Most importantly, we learned much during this year’s building product marathon. Here’s a summary of what we planned for and what we did:
Some of the more notable things in the last 12 months on the product side are that we launched the payment streaming infrastructure primitive and built an additional layer of products, like our on-chain dollar cost average scheduler, payroll, and the token vesting program. We also shipped a full-on DEX, a liquidity aggregator, the MEAN staking program, and the SuperSafe multisig.
We were lucky enough to have the support of excellent partners and integrators powering our liquidity and protocols, like Serum, Raydium, Orca, Solrise, Grape, Marinade, Jupiter, Socean, Credix, Phantom, Solflare, Triton, Alameda, Coinbase, Ledger and Brave and many more.
We also made substantial engineering improvements to our infrastructure with a fully automated DevOps pipeline implementation, double-audited smart contracts by Certik and Sec3, and several rounds of RPC disaster recovery architecture and rollouts. All to ensure the safety of our products and the reliability and uptime in mainnet.
Business & Ecosystem Highlights
On the business side, things moved a little slower than we would’ve liked, and we are still learning our way around when it comes to establishing good growth practices around community and distribution channels.
Even with those challenges, in the last year, we raised a private round of $3.5M, launched the MEAN governance token, did a massive airdrop, emitted 43% of the token supply, got MEAN listed in Gate, MEXC, BitMart, AAX centralized markets as well as the leading AMMs in Solana: Orca, and Raydium. Numerous versions and revisions of our DAO documentation and tutorials in more than six languages were made public. Our current social communities have over 100k followers and community members across Discord, Twitter, LinkedIn, and Medium. The mods and ambassadors of Mean DAO launched countless activities, events, collaborations, and shows like the “Building Web3”.
Between product integrations and business partnerships, the overall ecosystem is too large to mention everyone, but we have some friends 😍
We also received some love from media publishers, and we got featured in top publications like Forbes, Bloomberg, EFE, CoinDesk, and Refresh.
The results of these efforts have not been in vain. As of Sept 2022, we have 150k+ unique wallets in our dapp, 50k+ payments streaming, $32M TVL, 194 SuperSafe multisigs, and a little over $4 billion in transaction volume. Not too shabby for a 1-year-old baby :)
Although we are all swimming in a bear market at the moment, it is with great pride we look back at these accomplishments and look forward to a supercharged with possibilities for keeping our mission alive.
Those with a keen eye would have noticed that we’ve made a couple of strategy shifts (or, instead, extra clarity) on our roadmap.
Payment streaming infra
The first “adjustment” is a move to grow our payment streaming infrastructure primitive through DAO ecosystem incentives, so other developers/teams build on top of us instead of having the core team making many of those dapps. This means:
- We are focusing on Payment Streaming as a primitive protocol (ala Serum) and supporting the builders around it. We plan on having a Grants Ecosystem Program for developers and bug bounties as part of the on-chain governance.
- We are opening up the MeanFi dapp to bring additional DeFi banking and more accessible lending and borrowing opportunities directly on the app. Building in the open with the community means more collaborations, integrations, and faster release cycles.
Institutional self-custody infra
We are reinforcing our focus on institutional self-custody through multisigs, emphasizing user experience (UX), developer experience (DX), and TradFi bridging (on/off ramps).
We want to make the SuperSafe the equivalent of the Web3 App Store and, in many ways, a “Self-Custody Layer-Zero” that supports multi-chain self-custody workflows. We are having many convos on the DAO about how to deliver on this promise, operationally speaking. We will likely we’ll see some proposals regarding this direction pretty soon.
A protocol-first approach
“We solve problem X, with Y solution, in chain Z” is the wrong way to think about DeFi products. We prefer “we solve problem X with Y solution.” The second option means the chain becomes a low-level implementation detail that doesn’t limit how the solution solves the problem. For example, no one has ever heard Mark Zuckerberg say, “we solve global connectivity with the Facebook social media platform, in PHP”… that last part is extra, and nobody cares. One move to make this protocol-first approach is to start measuring the KPIs that matter for the business across chains instead of vanity metrics like TVL.
Lots have happened since we first launched in Solana, and since the beginning, we’ve known all too well the future is multichain. Knowing it and being prepared for it are two very different things, and now we are getting prepared for it and shifting our architecture to have a protocol-first approach rather than a chain-first approach. We are doing a lot of work under the hood to power up the next generation of DeFi services on Mean products. We are adjusting our roadmap to sync with the market, and development needs to execute in this direction.
Mean Finance is a protocol powering the future of real-time finance anchored by the pillars of DeFi with top privacy, security, and usability. Our mission is to establish our products and infrastructure as the ultimate financial equalizers for people and organizations worldwide.
Go check out our dapp at https://app.meanfi.com and be part of the DeFi revolution. We had an incredible first year! Time to raise our glasses and cheers to the next one! LFG! 🔥🔥🔥
Useful links for new Mean DAO & MeanFi users:
- How to easily configure token vesting in Solana
- Run crypto payroll with Mean Payment Streaming protocol
- Setup a multisig wallet in Solana in less than 5 mins

domain: economics


text:
In New Mexico, racial discrimination is banned under both the U.S. Constitution and Title VII of the U.S. Code. These laws prohibit employers from taking race into account in procedures for hiring, determining wage levels, or promotions and benefits.
What Must Be Proven in a Discrimination Claim?
The Equal Employment Opportunity Commission (EEOC) is the federal agency in charge of investigating workplace discrimination, and employees discriminated against must file a claim with the EEOC before taking the matter to court. Racial discrimination claims involve situations where an employers treat workers differently than other workers who are of a different race.
To be able to prove a claim of racial discrimination, the Alamogordo plaintiff additionally needs to show that the employer had an intent to discriminate, and that the discriminatory action was based on race. This intent is most often proven by showing that the employer preferentially treated those of other races and nationalities.
How Can an Alamogordo Lawyer Help with My Claim?
In certain instances, intent to discriminate may also be shown by using recorded statements by the employer regarding racial issues. Depending on where you file your claim, the procedural laws will vary greatly, and so an Alamogordo lawyer will help familiarize you with the requirements for your district. A good New Mexico attorney will also be able to advise you should you decide to file with the EEOC, and they can guide you towards other potential remedies while your case is pending.

domain: law


Mullvad VPN has posted a warning on its blog to inform its community, and more specifically those using the Android client, that some connection data is being leaked during the establishment of links with WiFi access points.
This basically opposes the VPN lockdown system as Google has documented it, which should route all network traffic, including connectivity checks, through VPN tunnels when the “Block connections without VPN” is active in the settings.
Additionally, these checks risk user identity unmasking under certain conditions while the user falsely assumes that they are using a secured, encrypted connection with no risky interruptions or leaks.
As Mullvad explained in its blog post, the issue was discovered during a security audit on its app, but there’s nothing that the VPN vendor can do to remediate the situation or mitigate the problem.
Hence, Mullvad has submitted a feature request to Google, asking the mobile OS maker to consider adding a feature that passes all requests through the VPN connection with no exceptions.
The data privacy problem discovered by Mullvad’s auditors is that no matter what VPN settings are used in Android, the mobile OS still leaks some connection data when establishing a connection with a WiFi access point.
The data that is exposed to potential snoopers includes the location of the WiFi points, the source IP address, DNS lookups, HTTPS, and NTP traffic, along with various metadata.
These aren’t directly linked to an identity but can be used to derive it and de-anonymize Mullvad users, or other VPN users, since this is a common issue for all Android VPN clients.
“The connection check traffic can be observed and analyzed by the party controlling the connectivity check server and any entity observing the network traffic.”
“Even if the content of the message does not reveal anything more than “some Android device connected”, the metadata (which includes the source IP) can be used to derive further information, especially if combined with data such as WiFi access point locations.”– Mullvad blog
Still, the VPN vendor underlines that exploiting the privacy gap would require the sophistication of a skillful attacker or a privileged monitoring position in the network. As such, the threat isn’t widespread.
Google responded to Mullvad’s request for a data traffic system that respects “Block connections without VPN” somewhat negatively, downplaying the importance of the exemptions.
More specifically, an Android developer stated that VPNs rely on the connectivity checks that cause the leaks and argued that the disclosed information isn’t adding anything to those already snooping at L2 connections.
Mullvad responded to this by saying connectivity checks are only useful for connecting to captive portals, and not all VPN users need split tunneling all the time, so there should be a way to disable them.
Additionally, the VPN vendor stated that access to L2 data isn’t possible throughout the network, so limiting data leaks would still be beneficial for a wide range of circumstances, including stopping ISP-level tracking.
The challenges of complete privacy on mobile devices
For years, we have alerted readers to the challenges of maintaining a high level privacy on mobile devices.
In our guide on controlling communication channels, we detailed numerous factors that could expose your identity and undermine your privacy when using mobile devices, whether they be Android or iOS:
- PCIe ports
- Ultra-Wideband (UWB)
Just a few months back, a similar concern was raised pertaining to iOS devices leaking data when connected to a VPN.
Needless to say, achieving a very high level of privacy on a mobile device remains a daunting task, and nothing has changed in that regard.
While some may see this report and conclude that using a VPN on mobile devices is futile, that would be short-sighted and foolish. Privacy is not an all-or-nothing proposition, especially in a world of mass data collection, targeted advertising, and surveillance capitalism.
Even with these leaks from Android connection checks, a VPN remains a crucial tool in a world where ISPs surveil their customers and sell the data to a giant network of third parties. A VPN will continue to encrypt your connection and effectively hide your browsing activity from these types of adversaries.
As to targeted advertising and the tracking networks that permeate most websites today, a VPN with a built-in ad blocker will also go a long way to elevating your privacy on mobile devices, regardless of the connection check situation with Android.
A little bit of privacy is a lot better than nothing.


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I found out earlier that 5V is not enough to drive the shutter glasses. With my breadboard setup for stereowrap, I fed 12V to the op amps from an external source. Now that I moved the thing to a strip board, I added a step up converter that generates 12V from the 5V available on the USB port. I used an LT1301 which comes with an application note for exactly my use case. It was easy to implement and worked from the first try.
Then I temporarily switched from an arduino duemillanove to a leo stick. Although it’s a tiny clone which plugs directly into an USB port, it still seemed like a bit of an overkill. I thought of using one of the AtTiny’s for that project. As I was not too familiar with these yet, I first did a hello world blinking LED’s. Soon after, I learned that neither the Attiny45 nor the AtTiny85 have a hardware UART. Well, I thought, there is an arduino software serial library. Arduino libraries are generally very easy to use in the IDE. But as I programmed the chip directly this time I wanted to stay within CodeBlocks/CMake and use the arduino library from here. Continue reading “LED debugging the stereowrap hardware”
Probably the first time I got in contact with one of the pen style payment slip readers, was when I was working for TCG. They only come with drivers for Windows and in the meantime also for Mac. I contacted their support more than once, asking for a linux driver. No success so far. So I decided to get one cheap from ricardo.ch (similar to ebay.com). I was really lucky, and got one that makes noise when shaking for CHF 5. A new one would cost more than CHF 200. They have a very effective way of making sure people buy new ones from time to time. They just don’t release drivers for the older devices on newer versions of Windows. Well, that happens a lot in the Windows world, that people are forced to buy new devices. So there are a lot of devices floating around on ricardo.ch which only run on WindowsXP 32bit. Mine is one of those, but since I want to use it on linux that should be no problem.
When I first plugged it in, the USB id was recognized correctly:
Bus 002 Device 010: ID 0a93:0002 C Technologies AB C-Pen 10
But that was about it.
Trying to capture the communication on the USB port worked nicely with WireShark under ubuntu. But as I had no driver for it, there was not much communication to monitor. So I had to capture on a Windows box. Not so easy in a Windows-free zone. I have a VMWare virtual machine on my harddisk that I used some time ago to maintain an ancient project. But the outdated WMWare-Player could not run with my current installation. I had to upgrade it. It compiled the kernel modules with some minor help. But then the VM wouldn’t boot. I suspect, they changed the hardware they emulate. That would be no problem with linux, but Windows has real trouble with changing hardware. That was the same reason, I could not migrate that VM to VirtualBox some years ago. So, I installed a new Windows VM with VirtualBox. But now I could not figure out how to make the USB device accessible to the guest OS. The next try was qemu. It’s not as point and clicky as the other two products, but it’s really powerful and comes with loads of features. I grow to like it ever more. Continue reading “payment slip reader”

domain: hobby


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Engaging youth in rural communities is the focus of our new workshop: Connecting with Youth: The Rural Way.
With a grant received from the Ontario Trillium Foundation, Parks and Recreation Ontario and Play Works are hosting four no-cost, day-long workshops in the fall of 2017.
These workshops are open to elected officials, economic development staff, advisory committees, youth services providers, business people, and/or those from rural communities with a keen interest in learning how to better engage and retain youth participation in local initiatives.
Registration is limited to 25 participants.
Click onto the following links for more information and/or to register:
October 25, Town of Minto--workshop is full. Please click below to put your name on the wait list and be notified of a second workshop in this area to be held in 2018.
October 26, Town of Gananoque
November 1, City of Orillia
November 22, Municipality of West Nipissing
For more information, contact Parks and Recreation Ontario at

domain: geography


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Onwards and upwards – exciting new paths lie ahead for LC
Koen Sandra |
Progress in LC over the years has been steady, but much slower than advances seen in techniques like GC. The lag can be attributed to the fact that LC is the core analytical technique of the pharmaceutical industry, in which regulation and validation – rather than development – were the keywords until the end of the 20th century. However, the past decade has seen great advances, thanks to the creativity of scientists from both the academic and industrial world. Today, with LC-MS/MS, we can monitor more than 300 pesticides in our food in less than 20 minutes, and quickly determine the critical quality attributes of large biopharmaceuticals. Developments in LC and MS have led to an increased understanding of the human body in health and disease, which could ultimately improve and extend our lives.
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domain: chemistry


text:
- Justin Bieber ditches his shirt at the gym - TMZ
- Elton John is NOT retiring - Gossip Cop
- Yara Shahidi started a fun new project - Just Jared Jr
- Selena Gomez wears pajamas and heels while shopping- Radar
- Milo Ventimiglia opens up about working with Will Smith - Lainey Gossip
- Moana hits big at the box offices for the second weekend - The Hollywood Reporter
Adam Sandler: 'That's My Boy' Out On DVD Now!
About Photo #2741490: Adam Sandler dons a "Southside 1971 Baseball" t-shirt while grabbing some coffee with his adorable daughter Sunny on Friday (October 19) in Brentwood, Calif. … Read More Here

domain: celebrity


PLACENTIA – Thursday’s Concert in the Park at Tri-City Park will feature Kid and Nic, a group boasting hot sax as well as current and old rock hits.
The concert starts at 6:30 p.m. and admission is free. Food will also be for sale.
Next week will be the Aquarius, a ’60s tribute band. The Placentia Symphonic Band directed by Jon Hausey will perform Aug. 4.
The Concerts in the Park series runs through Aug. 18. Information: 714-993-8232.


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According to a report by TechSci Research titled “United Kingdom Diabetic Foot Ulcer Treatment Market – By Region, Competition, Forecast and Opportunities, 2028”, the diabetic foot ulcer treatment market in the United Kingdom is projected to experience a substantial Compound Annual Growth Rate (CAGR) throughout the forecast period. This growth is primarily attributed to the advancements in the healthcare infrastructure of the country and the continuous development of the United Kingdom’s economy.
Rising Demand for Diabetic Foot Ulcer Treatment Fueled by Healthcare Expansion
The growing demand for diabetic foot ulcer treatment has been significantly influenced by the establishment of new hospitals in the United Kingdom every year. Statista’s analysis in 2022 reveals a trend where the United Kingdom witnessed the construction of approximately 1,910 new hospitals in 2018, followed by 1,978 hospitals in 2019, and 1,921 hospitals in 2020, among others. Additionally, the availability of around 17 thousand podiatrists in the United Kingdom, specializing in diabetic foot ulcer treatment with skilled techniques, is expected to drive the market’s growth during the forecast period.
Browse over XX Market Data Figures and spread through XX Pages and an in-depth TOC on ” United Kingdom Diabetic Foot Ulcer Treatment Market” – https://www.techsciresearch.com/report/united-kingdom-diabetic-foot-ulcer-treatment-market/15711.html
Advanced Treatment Techniques and Collaborations Fuel Growth
Contemporary podiatrists are employing innovative techniques for diabetic foot ulcer treatment, including the use of bioengineered skin substitutes like tissue-engineered dermal replacements and cellular-based products. These approaches accelerate wound closure and provide a framework for tissue regeneration. Healthcare professionals are also integrating methods such as pulsed electromagnetic field therapy (PEMF) to enhance wound healing by stimulating cell proliferation and circulation. The market is further supported by strategic mergers and acquisitions among major pharmaceutical companies, aiming to combine expertise and innovate treatment methods. For instance, a collaborative effort funded by the Engineering and Physical Sciences Research Council (EPSRC) between The Crick and GlaxoSmithKline plc. seeks to advance new drug target discovery with an investment of EUR 11.5 million.
Obesity and Healthcare Policies Driving Market Growth
The rising prevalence of obesity due to unhealthy dietary habits and sedentary lifestyles is expected to be a significant driver of the United Kingdom diabetic foot ulcer treatment market. According to global obesity levels, the United Kingdom ranks 33rd worldwide, with around 27.8% of its adult population classified as obese. The government’s analysis in 2022 reveals obesity rates among different age groups, further underscoring the impact of excess body weight on foot health. Additionally, the implementation of healthcare policies, exemplified by the National Institute for Health and Care Excellence (NICE) guidelines, provides evidence-based recommendations for preventing, assessing, and managing diabetic foot ulcers. The United Kingdom government’s funding for research and development initiatives related to diabetic foot ulcer treatment also contributes to market growth.
Challenges to Growth and Market Segmentation
Despite the positive trajectory, challenges such as the high cost of advanced wound care treatment and public unawareness about available diabetic foot ulcer treatments may impede market growth in the near future.
Segmentation of the United Kingdom Diabetic Foot Ulcer Treatment Market
The market segmentation is based on several factors:
- Ulcer type
- End user
Ulcer Types and Dominant Trends
The market is categorized into three ulcer types:
- Neuropathic ulcers
- Ischemic ulcers
- Neuroischemic ulcers
Among these, neuroischemic ulcers are anticipated to dominate the market during the forecast period. This dominance can be attributed to the heightened risks associated with neuroischemic ulcers, including infections, amputations, and even fatalities.
Some of the major companies operating in the United Kingdom diabetic foot ulcer treatment market include:
- Medtronic Ltd.
- 3M United Kingdom Public Limited
- ConvaTec, Inc.
- Coloplast Ltd.
- Smith & Nephew plc.
- B. Braun Medical Ltd.
- Medline Industries Ltd.
- Mölnlycke Health Care Limited
Customers can also request for 10% free customization on this report.
“Certain regions like London and East Anglia are expected to dominate the demand for diabetic foot ulcer treatment in United Kingdom. Presence of leading pharmaceutical companies in the market who are focusing on incorporating novel properties in their medicinal products for early treatment of diabetic foot ulcers are expected to register an impressive growth to United Kingdom diabetic foot ulcer treatment market in the forecast period,” said Mr. Karan Chechi, Research Director with TechSci Research, a research-based global management consulting firm.
“United Kingdom Diabetic Foot Ulcer Treatment Market By Treatment (Wound Care Dressings, Biologics, Therapy Devices, Antibiotic Medications, and Others), By Ulcer Type (Neuropathic Ulcers, Ischemic Ulcers, and Neuroischemic Ulcers), By End User (Hospitals & Clinics, Ambulatory Care Centers, and Others), By Region, Competition, Forecast and Opportunities, 2028”, has evaluated the future growth potential of United Kingdom diabetic foot ulcer treatment market and provides statistics & information on market size, structure, and future market growth. The report intends to provide innovative market intelligence and help decision makers take sound investment decisions. Besides, the report also identifies and analyzes the emerging trends along with essential drivers, challenges, and opportunities in United Kingdom diabetic foot ulcer treatment market.
Download Free Sample Report – https://www.techsciresearch.com/sample-report.aspx?cid=15711
About TechSci Research:
TechSci Research is a research-based management consulting firm providing market research and advisory solutions to its customers worldwide, spanning a range of industries. TechSci Research’s core values are value, integrity and insight. Led by a team of dynamic industry experts, TechSci Research provides its customers with high value market research and advisory services that helps them identify new market opportunities, growth engines and innovative ways to capture the market share. As a result, TechSci’s client leads rather than follow market trends. Not bound by legacy, TechSci’s cutting-edge research model leverages its decades of research knowledge and increased use of technology as engines of innovation to deliver unique research value. Provided as an alternative to traditional market research, TechSci Research reports do not just deliver data and knowledge rather highlights the insights in a more usable and interactive format for its clients.
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