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Stability indicating RP-HPLC method for the simultaneous determination of atorvastatin calcium, metformin hydrochloride, and glimepiride in bulk and combined tablet dosage form.
Metformin hydrochloride (MET) is an oral biguanide and chemically it is N,N-dimethylimidodicarbonimidic diamide (Figure 1(a)), which reduces the elevated blood glucose concentration in patients with diabetes but does not increase insulin secretion. It does not lower the glucose levels in nondiabetic subjects [1, 2]. Chemically glimepiride (GLM) is (Figure 1(b)) 3-ethyl-4-methyl-N-[2-[4-[(4-methylcyclohexyl) carbamoylsulfamoyl]phenyl]ethyl]-5-oxo-2H-pyrrole-1-carboxamide. GLM is an oral hypoglycemic agent that acts by stimulating the release of insulin from functioning pancreatic beta cells and increasing sensitivity of peripheral tissues to insulin [3-5]. Chemically, atorvastatin calcium (ATR) (Figure 1(c)) is ([beta]R, 8R)-2(4-flurophenyl)-[alpha],[delta]-dihydroxy-5-(1-methylethyl)-3-phenyl-4- [(phenylamino)carbonyl]-1-Hpyrrole-1-heptonoic acid trihydrate . Atorvastatin calcium (ATR) is a competitive inhibitor of HMG-CoA reductase used in the treatment of hyperlipidemia .
Fixed dose combination drugs are used to maintain steady state of glucose and lipid levels in blood plasma. Tablet dosage form (Tripill) contains an oral lipid lowering agent, atorvastatin, and two oral antihyperglycemic drugs, glimepiride and metformin hydrochloride. The combination of these three drugs complements each other and provides a reduction in plasma cholesterol along with glycemic control, thereby providing comprehensive control of diabetes associated with dyslipidemia.
The objective of the present investigation is to develop a simple and novel method for the simultaneous estimation MET, GLM, and ATR by employing HPLC. The literature search reveals that, few methods were reported for this combination in dosage form and in plasma [8-10], there are some other methods that are reported for individuals as well as individual drugs with other drug combinations [11-20]. The analytical method employed for the quantitative determination of drug in formulation plays a significant role in the evaluation and interpretation of drug release from the formulation. Therefore, a complete validation of analytical methods was performed according to ICH guidelines  to yield reliable results that could be satisfactorily interpreted. So, the proposed method can be employed for the determination of three dugs in bulk and combination formulations (Tripill) as well as in future studies of these drugs.
2. Materials and Methods
2.1. Instrumentation. The instruments employed in this study are HPLC-Perkin Elmer, UV-200 series with the total chrome Software, Waltham, USA; sonicator-Sharp Analytical, Hyderabad, India; analytical balance-Sartorius, German; Millipore Direct-Q 3 U.V. USA; pH meter-Systronics, Ahmadabad, India.
2.2. Standards and Chemicals. ATR, MET, and GLM were gift samples obtained from Aurobindo Pharma (Hyderabad, India). Purified water was obtained from a Millipore Direct-Q3 U.V. Acetonitrile of HPLC grade, o-phosphoric acid, and sodium dihydrogen phosphate were of A.R. grade and were purchased from Merck, Pvt. Ltd (Mumbai, India). Tripll 2 tablet dosage form with concentrations of ATR-10 mg, MET-500 mg, and GLM-2 mg was purchased from the market.
2.3. Stock and Working Solution Preparation
Preparation of Standard Stock Solution. Accurately weighed 10 mg of each drug, that is, MET, GLM, ATR and transferred into a 10 mL volumetric flask dissolved with small amount of solvent (acetonitrile: water 50:50) and made up of the volume with 50:50 v/v water and acetonitrile. Daily working standard solutions of mixture were prepared by suitable dilution of the stock solution with the mobile phase.
Preparation of a Buffer. Accurately weighed 2.72 g of potassium dihydrogen orthophosphate dissolved in 1000 mL of HPLC grade water and pH was adjusted to 3.0 by using orthophosphoric acid.
2.4. Chromatographic Conditions. The chromatographic separation was done by using Grace Smart Altima C-8 column (250 x 4.6 mm, 5[micro]) with mobile phase acetonitrile: phosphate buffer pH 3.0 (60: 40% v/v) at a flow rate of 1 mL/min and detection wavelength was 235 nm with 25 [micro]L of injection volume.
2.5. Method Optimization. The method development, top priority was given for the complete separation of drugs. The chromatographic method was optimized by changing various parameters, such as pH of the mobile phase, organic solvent and buffer used in the mobile phase, and composition of the mobile phase on trial error basis by varying one parameter and keeping all other conditions constant.
2.6. Method Validation. The validation parameters like linearity, sensitivity, accuracy, precision, recovery, and stability of drugs were studied according to the ICH guidelines .
2.6.1. Selectivity. Selectivity was studied by comparing the chromatograms obtained from the blank sample with the chromatogram obtained from a standard drug mixture.
2.6.2. Linearity. The linearity of this method was evaluated by linear regression analysis, using least square method, and the linearity of drugs was found in the concentration range of 20-200 [micro]g/mL for MET, 10-150 [micro]g/mL for ATR and GLM. Calibration standards are prepared by spiking the required volume of working standard (200 [micro]g/mL) solution into different 10 mL volumetric flasks and volume made up with mobile phase to yield concentrations of 10, 20, 30, 40, 50, 100, 150, and 200 [micro]g/mL of MET, GLM, and ATR. The resultant peak area of each drug was measured. Calibration curve is plotted between peak areas of drug against concentration of the drug.
2.6.3. Sensitivity. The LOD and LOQ of this method were verified based on the standard deviation of response, slope.
2.6.4. Intraday and Interday Precision and Accuracy and Recovery. Intra-and interday accuracy and precision of this method were determined at three different concentration levels in 3 different days. On each day, three replicates were analyzed with independently prepared calibration curves. The accuracy and precision were expressed as percentage accuracy and relative standard deviation (RSD), respectively.
2.6.5. Recovery. The recovery study was carried out at three levels of 80% (40 [micro]g/mL), 100% (50 [micro]g/mL), and 120% (60 [micro]g/mL) of standard drug was added to the extracted solution of formulation, diluted the solution and injected into HPLC, then calculated the recovery.
2.6.6. Robustness. Robustness of the method was done by changing slight variation in the parameters like mobile phase composition, flow rate, and wavelength. Present method did not show any significant change when the critical parameters were modified (i.e., mobile phase composition, flow rate, and pH of buffer).
2.6.7. Solution Stability. The stability of the drug solution was determined for the short-term stability and autosampler stability. Short-term stability was carried out by keeping at room temperature (25[degrees]C) for 24 h. Autosampler stability was determined by storing the samples for 24 h in the autosampler. Each sample injected three times into HPLC and concentrations obtained were compared with the nominal values of the quality control (QC) samples.
2.6.8. Forced Degradation Study. The stress studies were carried out by taking 100 mg of each drug into 100 mL volumetric flask and added 5 mL of 1M hydrochloric acid for acid degradation, 5 mL of 1M sodium hydroxide for alkali degradation, and 10 mL of water for hydrolytic degradation; then samples were kept in a water bath at 60[degrees]C for 1h. After heating, the solutions in volumetric flasks were neutralized, that is, 1M HCl with 1M NaOH, 1M NaOH with 1M HCl and volume made up with the mobile phase separately. Photodegradation was carried out by the drug was kept under UV light 254 nm for 24 h. Then diluted the drug solution with mobile phasetoget suitable concentrationwithinthe linearity range and injected the samples into the HPLC.
2.7. Analysis of Marketed Formulation. 20 tablets were weighed and finely powdered, and an accurately weighed sample of powdered tablets equivalent to 10 mg of ATR, 500mg of MET, and 2mg of GLM (equivalent to one tablet) was extracted with different extraction solvents like acetonitrile, methanol, water, and mobile phase. The recovery of drugs (ATR and GLM) was found to be less than 50% when extracting by using 100% water and the recovery of MET was found to be less than 90% when extraction carried out by using acetonitrile. The 100% recoveries of all three drugs were found when extraction carried out by using the combination of water and acetonitrile (50: 50) as extraction solvent. Hence, the composition of 50 : 50 v/v of acetonitrile: water was used as extraction solution. The powder equivalent to one tablet was transferred and extracted with 50 : 50 of acetonitrile: water in a 100 mL volumetric flask and sonicated for 15 min. This solution was filtered through Whatman number 1 filter paper. The solution obtained was diluted with the mobile phase so as to obtain a concentration in the range of linearity previously determined, and then filtered through 0.22 [micro] syringe filter. The amount of drugs recovered was calculated from the respective linear graph.
3. Results and Discussion
During the method development, top priority was given for the complete separation of drugs. The chromatographic method was optimized by changing various parameters, such as pH of the mobile phase, organic solvent and buffer used in the mobile phase, and composition of the mobile phase on trial error basis. Phosphate buffer in various strengths are tried along with methanol and acetonitrile as organic solvent. A mixture of acetonitrile and phosphate buffer with different pH values was tried. At pH 3.0 the separation was good enough; then the proportions of acetonitrile and phosphate buffer pH 3.0 were tested as a mobile phase with Grace Smart C-8 columns. The mobile phase composition of 40 :60 v/v phosphate buffer: acetonitrile was shown to have good resolution and retention time with minimal tailing factor in acceptable range. The method was optimized with the mobile phase composition of acetonitrile and phosphate buffer 60: 40 (v/v). Buffer molarity of 10, 20, and 50 mM was tested. There were no significant changes in the chromatographic response and peak shape with change in buffer molarity. A buffer molarity of 20 mM was selected for further analysis.
After several trials, the method was optimized as a mixture of 20 mM potassium dihydrogen phosphate buffer (pH 3.0) and acetonitrile (40: 60 v/v) at a flow rate of 1 mL/min and at 235 nm by using Grace Smart, Altima C-8 column. These chromatographic conditions achieved satisfactory resolution, retention time, and tailing for three drugs of MET, GLM, and ATR. Figure 2 shows that chromatogram of standard drug mixture and these are well separated from each other.
The standard mixture solution was used as a system suitability solution it was injected into HPLC. The retention time, tailing factor, resolution, and theoretical plates for each drug were observed. The percentage relative standard deviation (%RSD) of five consecutive injections for each parameter was calculated. The system suitability parameters of the present method were found to be within acceptable limits. The system suitability data are presented in Table 1. The acceptable limits of the resolution between two adjacent peaks should be [greater than or equal to] 2 and tailing factor should be [less than or equal to] 2  and the %RSD of these values should be [less than or equal to] 2. System suitability tests confirmed that the chromatographic system was adequate for the analysis planned to be done.
The linearity was performed and calibration curve is plotted between peak areas of drug against concentration of the drug. The curve was linear over the range of 20-200 [micro]g/mL for MET and 10-150 [micro]g/mL for ATR and GLM. The regression equations of three drugs were y = 79069x - 23231 ([r.sup.2] = 0.998) for MET, y = 33694x - 45799 ([r.sup.2] = 0.998) for ATR, and y = 47641x - 49907 ([r.sup.2] = 0.999) for GLM. The results of intra- and interday precision was shown in Table 2. The %RSD was found to be less than 2 for all the drugs which indicates that the method is precise. Recovery experiments were done to determine the accuracy of method. The results are represented in Table 3. The data indicated good accuracy and reproducibility.
Present method did not show any significant change when the critical parameters were modified. The tailing factor for the drugs was always less than 2.0 and the components were well separated under all the changes carried out (i.e., mobile phase composition, flow rate, and pH of buffer). Considering the modifications in the system suitability parameters and the specificity of the method, as well as carrying the experiment at room temperature, may indicate that the proposed method was robust.
The stability of the drug was studied for short-term and autosampler stability using the QC samples. The samples were analyzed and compared with freshly analyzed QC samples; no differences were found in accuracy and precision. The stability data presented in Tables 4 and 5 indicate that there were no major changes observed in this study.
Forced degradation studies were carried out in acid, base, and neutral conditions; ATR was degraded more (30.19%) in acidic conditions than basic and neutral conditions. In basic conditions MET was degraded more (30.5%) compared to the other two drugs; no degradation was found in hydrolytic conditions. The amount of GLM in acid and hydrolytic conditions was reduced, but there was no reduction in the amount of GLM in basic conditions. The results of stress study indicate that ATR is unstable under these conditions. Two degradation peaks were appearing at retention time of 5.2 min and 9.62 min in the chromatogram under applied stress studies. These degradation peaks were not interfering with their parent peaks. Hence this method could be employed for the determination of these three drugs, that is, MET, GLM, and ATR in the presence of their degradation product. Under photodegradation study ATR degraded 4% and no degradation was found for MET and GLM. The chromatograms of stress conditions are shown in Figure 3 and the percentage degradation of each in stress studies of MET, GLM, and ATR were represented in (Table 6).
The results of assay of dosage form percentage recovery was found to be more than 98% for all the drugs (ATR, MET, and GLM); the data was represented in Table 7; the chromatogram from formulation was shown in (Figure 4).
The developed method possesses good selectivity and specificity; there is no interference found in the blanks at retention times of ATR, MET, and GLM and good correlation between the peak area and concentration of the drug under optimized conditions. The recovery studies are found to be >98% for three drugs. The observation of %RSD less than 2 for both intra- and interday measurements indicates a high degree of precision. In the present method, a Grace Smart, Altima C-8 column has been used at a flow rate of 1 mL/min. The method was optimized with low injection volume. The stability of ATR, MET, and GLM were found to be within the limits indicating that there is no degradation of drugs during the daily analysis. This method was applied for the simultaneous determination of ATR, MET, and GLM in tablet dosage form.
Conflict of Interests
The authors declare that there is no conflict of interests regarding the publication of this paper.
The authors are thankful to Aurabindo Pharma limited, Hyderabad, Andhra Pradesh, India, for providing drugs and to the Alliance Institute of Advanced Pharmaceutical and Health Sciences for providing all types of facilities for the research.
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Devi Ramesh (1) and Mohammad Habibuddin (2)
(1) Government Polytechnic for Women, Gujarathipeta, Srikakulam, Andhra Pradesh 532005, India
(2) Adept Pharma & Bioscience Excellence Private Limited, 10-3-561/3A/102, Vijayanagar colony, Hyderabad, Andhra Pradesh 500057, India
Correspondence should be addressed to Devi Ramesh; firstname.lastname@example.org
Received 19 March 2014; Revised 12 July 2014; Accepted 13 July 2014; Published 30 October 2014
Academic Editor: Hugh J. Byrne
Table 1: System suitability parameters of ATR, MET, and GLM. Parameter MET ATR Mean [+ or -] SD %RSD Mean [+ or -] SD %RSD Rt 2.57 [+ or -] 0.04 1.75 7.06 [+ or -] 0.13 1.90 TF 1.25 [+ or -] 0.01 0.92 1.15 [+ or -] 0.01 1.00 Rs 9.38 [+ or -] 0.18 1.92 -- -- TP 3556 [+ or -] 64 1.82 4872 [+ or -] 93 1.92 Parameter GLM Specifications Mean [+ or -] SD %RSD  Rt 9.39 [+ or -] 0.11 1.23 RSD [less than or equal to] 2 TF 1.11 [+ or -] 0.01 0.89 TF [less than or equal to] 2 Rs 5.27 [+ or -] 0.06 1.18 TP 6280 [+ or -] 30 0.489 N > 2000 Rt; retention time, TF: tailing factor, Rs: resolution, and TP: theoretical plates; n = 5. Table 2: Conc in MET ATR [micro]g/ Mean [+ or -] %RSD Mean [+ or -] %RSD mL SD SD Intraday (n = 6) 10 -- -- 99.82 [+ or -] 1.153 1.151 20 99.36 [+ or -] 0.137 106.73 [+ or -] 1.468 0.137 1.567 50 100.08 [+ or -] 1.992 98.95 [+ or -] 0.225 1.994 0.222 100 102.67 [+ or -] 0.383 102.04 [+ or -] 0.200 0.393 0.204 Intraday (n = 9) 10 -- -- 99.15 [+ or -] 0.598 0.593 20 100.43 [+ or -] 1.665 103.17 [+ or -] 1.287 1.672 1.328 50 98.20 [+ or -] 1.025 100.22 [+ or -] 0.694 1.007 0.695 100 101.45 [+ or -] 0.204 98.37 [+ or -] 1.360 0.207 1.338 Conc in GLM [micro]g/ Mean [+ or -] %RSD mL SD Intraday (n = 6) 10 105.02 [+ or -] 0.225 0.236 20 104.27 [+ or -] 0.801 0.835 50 100.78 [+ or -] 0.301 0.303 100 103.14 [+ or -] 0.591 0.610 Intraday (n = 9) 10 103.57 [+ or -] 1.373 1.422 20 102.45 [+ or -] 0.346 0.355 50 100.82 [+ or -] 0.215 0.217 100 100.92 [+ or -] 1.072 1.082 Table 3: Recovery study of ATR, MET, and GLM. Add. MET ATR conc. Obt. (%) Obt. (%) conc. Recovery conc. Recovery 80% 39.49 98.74 40.02 100.05 [+ or -] [+ or -] [+ or -] [+ or -] (40) 0.12 0.30 0.25 0.64 100% 50.49 100.98 48.72 97.45 [+ or -] [+ or -] [+ or -] [+ or -] (50) 0.33 0.67 0.17 0.35 120% 59.8 99.67 61.17 101.96 [+ or -] [+ or -] [+ or -] [+ or -] (60) 0.70 1.17 0.93 1.55 Add. GLM conc. Obt. (%) conc. Recovery 80% 40.57 101.44 [+ or -] [+ or -] (40) 0.36 0.92 100% 49.05 98.1 [+ or -] (50) 0.03 0.07 120% 60.51 100.86 [+ or -] [+ or -] (60) 0.16 0.27 Add. conc.: added concentration; Obt. conc.: obtained concentration; n = 3. Table 4: Short-term stability data of ATR, MET, and GLM. Conc. In MET ATR [micro]g/ Mean [+ or -] %RSD Mean [+ or -] %RSD mL SD SD 10 -- 97.17 [+ or -] 1.133 1.101 20 99.66 [+ or -] 0.338 100.15 [+ or -] 1.793 0.337 1.813 50 100.5 [+ or -] 1.055 99.49 [+ or -] 0.314 1.108 0.313 100 101.43 [+ or -] 0.197 99.56 [+ or -] 1.283 0.199 1.277 Conc. In GLM [micro]g/ Mean [+ or -] %RSD mL SD 10 102.95 [+ or -] 1.016 1.046 20 101.69 [+ or -] 0.634 0.644 50 100.79 [+ or -] 0.411 0.414 100 102.43 [+ or -] 1.054 1.079 Table 5: Autosampler stability data of ATR, MET, and GLM. Conc. in MET %RSD ATR %RSD [micro]g/ Mean Mean mL [+ or -] SD [+ or -] SD 10 -- 100.38 [+ or -] 0.938 0.942 20 101.29 [+ or -] 1.075 100.36 [+ or -] 0.707 1.089 0.71 50 98.82 [+ or -] 0.657 98.56 [+ or -] 0.631 0.649 0.622 100 99.94 [+ or -] 1.479 99.04 [+ or -] 0.674 1.478 0.667 Conc. in GLM %RSD [micro]g/ Mean mL [+ or -] SD 10 99.69 [+ or -] 1.054 1.05 20 100.86 [+ or -] 0.189 0.191 50 101.13 [+ or -] 0.234 0.237 100 100.27 [+ or -] 1.04 1.043 Table 6: Forced degradation studies data of ATR, MET, and GLM. %assay met %assay ATR %assay GLM %Drdn. %Drdn. %Drdn. Acid 99.52 0.48 69.8 30.19 93.6 6.4 Base 69.5 30.5 88.5 11.49 100.2 -- Hydrolysis 101.46 -- 92.91 7.08 91.14 8.86 Photolysis 99.82 0.18 96.2 3.8 99.25 0.75 Drdn: degradation; n = 3. Table 7: Assay of formulation. MET Assay ATR Assay GLM Assay (500 mg) (%) (10 mg) (%) (2 mg) (%) Amount Amount Amount Tripill 508.54 101.7 9.88 98.89 1.96 98.18 2 [+ or -] [+ or -] [+ or -] 13.61 2.72 0.097 0.97 0.021 1.06 n = 5. Amount mentioned in brackets are label claim of tablet.
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|Title Annotation:||Research Article; reversed-phase high-performance liquid chromatography|
|Author:||Ramesh, Devi; Habibuddin, Mohammad|
|Publication:||International Scholarly Research Notices|
|Date:||Jan 1, 2014|
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text:
Rashmika Mandanna made her debut in Telugu film Industry with Chalo, where she shared the screen space with Naga Shaurya. It is known news that she had got engaged to Kannada actor Rakshit Shetty in 2017. Both Rashmika Mandanna and Rakshit Shetty have worked together for the movie Kirik Party. According to the latest buzz in the film Industry, Rashmika Mandanna is planning to break his relationship with Rakshit Reddy as she want to establish herself in Tollywood. The sources close to her say, very soon she will make an announcement regarding her relationship split.
After the engagement with Rakhit Shetty, when Rashmika Mandanna was asked, Is Rakshit Shetty the dream guy with whom she wanted to get married? She said, “I wanted to get married to a guy who was not from a film background, who would come back home from a typical desk job and spend the rest of evening with me, and wanted him to give me full attention. But Rakshit Shetty is completely opposite to that. He is from the industry, he can’t give me enough time given his commitments.” She laughed and added, “He is very unromantic.”
The actress who won million of hearts with her wonderful performances in Chalo, is currently romancing with Arjun Reddy fame Vijay Deverakonda in Geetha Govindam, in the direction of Parasuram, which is scheduled to hit the theaters on 15th August 2018, on the occasion of Independence day. Rashmika Mandanna is flooding with number of offers from top production house in Telugu Film Industry.
It is heard that the relationship between Rashmika Mandanna and Rakshit Shetty is not going well as the actress is not showing any interest. Post her Telugu debut, her career is on an upswing and she is busy in signing her new projects. Rashmika Mandanna wants to concentrate on her career and do more Telugu films in Tollywood. So she is planning to drop the idea of her wedding. It has also come out that when Rakshit Shetty tried to call Rashmika Mandanna recently, she did not even respond to his call. Their engagement may break at any time. Recently both Rakshit Shetty and Rashmika Mandanna were spotted together at short films awards ceremony.
Once again Rashmika Mandanna will share the screen space with Vijay Deverkonda in an upcoming movie Dear Comrade in the direction of Bharat Kamma.

domain: celebrity


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SMBC Aviation Capital has ordered 25 737-8s – increasing its backlog to 81 737 MAX jets. With travel demand surging around the globe, lessors are looking to increase their single-aisle portfolios to provide airlines with more fuel-efficient jets capable of operating across various route networks. “We are pleased to conclude this further order with our long-standing partner Boeing and we look forward to working closely with them in the future. This transaction demonstrates our commitment to provide our customers with the latest-technology, most fuel-efficient aircraft, as they seek to meet their own sustainability objectives and reduce operating costs,” said Peter
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domain: economics


BANGKOK -- Thailand's largest industrial estate developer is restructuring its investments to align with the country's rapidly changing business landscape amid the coronavirus pandemic.
Amata has decided to revise its business plan to invest 5 billion baht ($160 million) over five years to 2023 in Thailand and Vietnam, while gearing up for a post-COVID rebound in the economy.
The developer hopes to beat the gloomy sentiment caused by COVID-19 at home and political instability in other parts of the region, said an analyst from KTB Securities. In particular, Amata senses opportunity in digitization, a trend that continues to grow in the business sector.
"COVID-19 is a key factor, driving us onto the digital platform to increase the productivity and efficiency of our clients," said Viboon Kromadit, Amata's chief marketing officer, in an interview with Nikkei Asia.
Under Amata's revised plan, most of its investment money will target development of 5G network infrastructure and general modernization at its industrial estates. Ultimately, the company wants to transform these properties into "smart cities" equipped with digital platforms, renewable power and advanced medical centers.
Thailand's population is ageing, sending labor costs uncomfortably high and threatening the nation's competitiveness. Hence, Amata needs to rely more on digital and advanced technology to move all industrial estates toward next-generation industries, said Viboon.
Amata has developed more than 7,000 acres in Chonburi and Rayong provinces that 1,100 factories now call home. To help its foray into digitization, Amata is partnering with AIS, the country's biggest mobile operator, to install 5G networks at its industrial estates. It is also working with B Grim, a leading power company, to develop a 133-megawatt cogeneration power plant for its power-hungry tenants.
Despite its moves, Amata faces headwinds caused by COVID-19. Amata posted a net profit of 1.1 billion baht ($35 million) in 2020, down 36% from the previous year when it had a net profit of 1.7 billion baht.
Normally the company sets a real estate sale target at around 395 acres per year. However, COVID-19 has disrupted business and forced the company to lower its goal this year to 355 acres.
Adding to headwinds has been the coup in Myanmar, which has forced Amata to delay a $1 billion smart city project in the country. "We have around a dozen staff working there. However, all of them are now back in Thailand and we just have to wait and see whether the situation will return to normal," Viboon said.
The Yangon Amata Smart and Eco City is spread out over 2,000 acres in Yangon. The smart city would have started generating revenue this year were it not for the coup, which has spooked foreign investors.
Beyond its move into digitization, Amata sees Vietnam as a potential panacea to headwinds elsewhere. The company has been investing there for more than two decades. Investment in the country from 2015 through 2020 reached $108 million. Over the next five years, Amata plans to invest at a much faster rate.
Amata does not have any near- to medium-term plans to expand outside of Southeast Asia. "What we are trying to do is to develop industrial estates within [the Association of Southeast Asian Nations bloc] to link further to China's Belt and Road initiative," Viboon said.
He added that Belt and Road projects will bring in a great deal of Chinese money.


Close to 121,000 Xbox One video game controller battery chargers are being recalled due to a burn hazard.
According to the U.S. Consumer Product Safety Commission, the recall covers Energizer Xbox One 2X Smart Chargers used to charge the console’s video game controllers. The agency said the company has received 24 reports of the chargers overheating and deforming the charger’s plastic cover, including 6 reports of chargers emitting a burning odor. Thus far, no injuries have been reported.
The CPSC advises consumers to immediately stop using the recalled battery chargers and contact Performance Designed Products to return the chargers for a full refund.
For more information, click here.


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SEASON 5 SPOILERS INCLUDED!I'm really excited for season 6 and this fan-made trailer is my hope for how the tone of the final season will play out. Song: htt. The fifth season of the AMC television series Better Call Saul premiered on February 23, 2020, in the United States, and concluded on April 20, 2020. The ten-episode season was broadcast on Mondays at 9:00 pm in the United States, except for the premiere which aired on a Sunday. Bob Odenkirk, Jonathan Banks, Rhea Seehorn, Patrick Fabian, Michael Mando, and Giancarlo. The final season concludes the complicated journey and transformation of its compromised hero, Jimmy McGill, into criminal lawyer Saul Goodman. From the cartel to the courthouse, from Albuquerque to Omaha, season six tracks Jimmy, Saul and Gene as well as Jimmy's complex relationship with Kim, who is in the midst of her own existential crisis.
Streaming, rent, or buy Better Call Saul - Season 6: Currently you are able to watch "Better Call Saul - Season 6" streaming on Sling TV, AMC+ Amazon Channel, AMC+ Roku Premium Channel, AMC+, DIRECTV or for free with ads on The Roku Channel. It is also possible to buy "Better Call Saul - Season 6" as download on Microsoft Store, Apple iTunes. Contents. episode 11 of Better Call Saulwhich in the last few hours was announced that it will be titled “Breaking Bad”, will premiere in the United States on AMC on the night of Monday, August 1, while it will arrive in the rest of the world on Netflix on Tuesday, August 2. From the name of the new chapter, it is believed that Walter White. The sixth and final season of the AMC television series Better Call Saul premiered on April 18, 2022, in the United States, and is scheduled to conclude on August 15, 2022. The thirteen-episode season is broadcast on Mondays at 9:00 pm in the United States on AMC and AMC+, and is published on Netflix the Tuesday after outside of the United States. . The season is split into.

domain: entertainment


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In this clinical webinar, Dr. Robert Post reviews and explains the data behind there being a higher incidence of childhood onset bipolar disorder in the United States than in Germany, the Netherland, and many other European countries. Bipolar disorder in the US runs a more difficult course in the US than in Europe. Earlier recognition and preventative treatments are needed to head off illness progression and treatment resistance. When a review of the variety of medications, their mechanics, and comorbidities is done, better effectiveness can be achieved even with fewer side effects.
Robert M. Post, MD is a member of IBPF’s Scientific Advisory Board, part of the Bipolar Collaborative Network in Chevy Chase, MD, and was a Clinical Professor of Psychiatry, George Washington, School of Medicine.
Dr. Post graduated from Yale University in 1964, the University of Pennsylvania School of Medicine in 1968, and interned at the Einstein School of Medicine in 1969. His Psychiatry residency was completed at the Massachusetts General Hospital, NIMH, and George Washington University. He was Chief, Biological Psychiatry Branch for many of his 36 years at the NIMH where his research focused on better understanding and treating patients with refractory unipolar and bipolar illness. His group has won major awards from the Society of Biological Psychiatry, APA, ACNP, Anna Monika Foundation, NARSAD, NDMDA, NAMI, ACP, ISBD, and the CINP. He is on multiple editorial boards and has published more than 1,070 manuscripts. He is the: author of a book entitled “Treatment of Bipolar Illness: A Casebook for Clinicians and Patients”; and editor of the Bipolar Network News (BNN), a quarterly free newsletter available online at www.bipolarnews.org. He founded the Childhood Mood Disorders Initiative, which allows parents to weekly rate their child’s severity of anxiety, depression, ADHD, oppositional behavior, and mania so these can be printed out and taken to their treating physician.
Recorded on December 13th, 2021.


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CBD Store in Barnum MN 55707 (46.5196, -92.6292) - CBD Tinctures
Some individuals take CBD as component of their day-to-day regimen, a lot like taking a multivitamin. While CBD is not a clinical product and there's no assurance it can assist with clinical conditions, researches show that many users report finding CBD helpful for things like discomfort, anxiousness, as well as rest.
The normally calming impacts of some cannabidiol products make them perfect for those that desire a secure, organic sleep treatment. Whether you're dealing with serious insomnia or just want a better evening's rest, after that it's well worth checking out CBD. There are numerous efficient methods to take CBD and, by combining them, you can develop an ideal nighttime CBD recipe to promote rest. Right here's exactly how.
CBD is an all-natural chemical or cannabinoid that's generally removed from hemp plants for use in all sort of useful items. It's important to keep in mind that these items are not FDA-regulated and there's no warranty that they can assist with any type of type of health and wellness problem. There are many researches which recommend that cannabinoids have much restorative capacity.
A 2019 study in The Permanente Journal tested out whether making use of CBD might assist subjects with stress and anxiety and sleep. After a month of taking a day-to-day dose of CBD, the study located that users reported lower levels of stress and anxiety as well as much better rest.
An additional research found that individuals who took a single 160mg dose of CBD rested dramatically far better than individuals that took a sugar pill. While customers who took 40mg as well as 80mg doses really did not experience the exact same sedative results, they reported much less dream recall, which may be beneficial to customers who suffer from night terrors or PTSD.
While there's no guarantee CBD will certainly make you sleep much better, several users report that it does help. With no dangerous negative effects and numerous easy ways to use it, it doesn't harmed to use CBD as an all-natural sleep help.
One of the best approaches to utilize CBD to promote rest is to use CBD Tincture. CBD Cast is an oil-based cannabidiol product which just takes a number of minutes to utilize as well as is absorbed right into your body additional fast.
To take CBD Tincture, apply your wanted dosage of oil under your tongue with the supplied dropper as well as hold it there for around 30-90 seconds. The cannabidiol is absorbed into your system sublingually as well as affixes to cannabinoid receptors in the body. You can swallow the remainder of the oil.
Making Use Of CBD Tincture around an hour prior to you intend to visit rest is a great way to enhance your nighttime routine. There are likewise a few other therapeutic ways to use CBD, and integrating CBD Cast with these may function much more efficiently.
One more amazing means to use CBD to boost sleep is to use a CBD Bath Bomb. These are topical CBD products which you can drop into your bathroom as well as soak up with the skin. In addition to being an effective method to soak up cannabidiol, the ingredients in CBD Bath Bombs supply a stress-free kind of aromatherapy which will aid you relax prior to bed.
To utilize CBD Bathroom Bombs, all you require to do is apply one bath bomb into a bathroom full of hot water. After that, you can get in and absorb the benefits. You may want to invest around 20 minutes in the bathtub to take in the great aroma as well as take in the CBD.
CBD Bath Bombs come in numerous fragrant fragrances which can promote leisure. Whether you choose Floral Scents, Open Area or Fresh Air, making use of among these in the evening is a terrific method to blow off anxiety prior to going to bed.
Attempt mixing your very own CBD Drink if you want an extra pleasurable and also restorative method to utilize CBD. There are several efficient means you can do this. You can either infuse beverages with CBD Cast or assimilate some potent CBD Separate Powder to instantaneously enhance your drink with a dosage of cannabidiol.
There are many read review CBD Consume alcohol Recipes you can utilize, although you'll wish to avoid any type of high-caffeine or sugary beverages if you're trying to get a great night's sleep. One idea is to instill a mug of warm cacao, chamomile tea or warm milk with some CBD. These beverages are understood for advertising sleep, as well as including some CBD will only make them better.
You will not wish to consume a CBD Beverage also close to bedtime- it might make you need to awaken to head to the commode. Having some CBD-infused hot chocolate or decaffeinated tea around an hour or so prior to going to bed click for more info can be an excellent means to naturally calm yourself.
Each of these techniques can be kicking back enough by itself. For those who want to really feel added loosened up and also stress-free, you may want to incorporate these for a powerful nighttime CBD dish.
Around an hour or two before bedtime, treat on your own to a CBD-infused cup of hot chocolate, decaffeinated tea or cozy milk. You could likewise intend to take some CBD Cast for added potency.
You can after that take a relaxing warm bath with an aromatic CBD Bath Bomb. With numerous naturally-soothing fragrances, it's a great way to naturally make on your own really feel much more prepared and tranquil to rest. By the time you hit your bed, you'll most likely feel tired sufficient to fall into a deep sleep.
With many naturally-relaxing CBD products from Bath Bombs to Oils, utilizing these methods can be a great means to make on your own really feel sleepy and also relaxed. You can additionally use these techniques together for a great CBD nighttime regimen.
There are various other methods you can attempt, as well. Some individuals discover vaping CBD Oil or CBD Vape Cartridges relaxing. You can likewise make use of Sugar-Free CBD Gummies or CBD Dried Fruit as a yummy late-night snack. Whichever way, every one of these products are safe to make use of without potential for harm or misuse.
While CBD is not a clinical item and also there's no guarantee it can aid with medical problems, researches show that several users report discovering CBD practical for points like stress and anxiety, pain, and also sleep.
There are several efficient methods to take CBD and, by combining them, you can create a best nighttime CBD recipe to promote sleep. An additional great way to make use of CBD to improve sleep is to utilize a CBD Bath Bomb. If you want an additional satisfying and healing method to use CBD, then try mixing your very own CBD Drink. You can likewise use Sugar-Free CBD Gummies or CBD Dried Fruit as a delicious late-night snack.
CBD Store in Barnum MN 55707 (46.5196, -92.6292) - CBD Creams
CBD contains a substantial probable for cutting down ache serving as A vital component for dealing with Degenerative Disc condition.
I reside in TN and Hemp is legal but these idiots We have now working our condition only made CBD oil authorized for selected teams. I've RSD/CRPS so what would you advocate as far Hemp products to test?
Crohn’s is also known as an vehicle-immune ailment. This means why not check here that the immune process of the body is definitely attacking its have GI tract. It's because There exists a dysfunction that may be resulting in the body to understand the GI tract cells as threats.
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Like fatty acids, CBD has an anti-inflammatory impact on your body, which can aid relieve The stress that Lots of people carry from strain and advertise recovery from workout.
It communicates with and oversees all the key devices of the body such as the central anxious method, the GI tract, the immune system, In combination with a lot of additional.
Each pressure is effective appropriately, but the strains which has official statement a substantial information of THC are decided on for combating the back again suffering. CBD is helpful in lowering the inflammation leading to diminished pain.
The study was done on rats wounded on tailbone by way of needles to mimic the degenerative disc disease, and all of these have been divided into 3 groups, Every single one of them were launched with diverse concentrations of CBD oil,i.e., all around thirty, sixty and 120 nmol.
The abundance of fatty acids may well make the oil a superb option for cbd oil at boots nourishing the skin and protecting it from inflammation, oxidation, along with other triggers of ageing.
These are specified as a muscle relaxant to sufferers suffering from back suffering or bursitis and any other kinds of inflammatory disorders. The NSAIDS result in adverse consequences including belly cramps, ulcers or constipation.
Because organic hemp oil is extracted from higher-CBD, small-THC cannabis, it doesn’t create psychoactive consequences the way in which THC does, which makes it a secure and authorized option for all age teams and demographics. It won't get you high
Have a look at our existing featuring of CBD vape oil and vaporizers. For those who have any questions about our merchandise or procedures, make sure you don’t be reluctant to Get in touch with us. Our aid workforce is always right here to lend a supporting hand.
(THC). This is the element of cannabis that is certainly popular for supplying you with a "superior" any time you smoke or consume the plant. THC binds to receptors in your brain called cannabinoid-1 receptors to be able to create these consequences.
I’m undecided about delivery it, however it’s lawful so shouldn’t become a issue. Look up dispensaries as part of your shut vicinity and connect with thrm. There challenge solved…good luck


Brand Name: EkelundDecorate for fall with the rich colors in this Betty Svensson designed Ekelund towel. Made in Sweden of 100% organic cotton, this towel is 16" x 24". Machine wash, drip dry. Ekelund Weavers is a family-owned company operating since 1692. Ekelund products withstand the test of time and can be collected and cherished by generations.
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Cell growth-the primary determinant of cell size-has an intimate relationship with proliferation; cells divide only after they reach a critical size. Despite its developmental and medical significance, little is known about cellular pathways that mediate the growth of cells. Accumulating evidence demonstrates a role for autophagy-a mechanism of eukaryotic cells to digest their own constituents during development or starvation-in cell size control. Increasing autophagic activity by prolonged starvation, rapamycin treatment inhibiting TOR (target of rapamycin) signaling, or genetic intervention, causes cellular atrophy in worms, flies and mammalian cell cultures. In contrast, we have shown that in the nematode Caenorhabditis elegans mutational inactivation of two autophagy genes, unc-51/Atg1 and bec-1/Atg6, confers reduced cell size. We argue that physiological levels of autophagy are required for normal cell size, whereas both insufficient and excessive levels of autophagy lead to retarded cell growth. Furthermore, we discuss data suggesting that the insulin/IGF-1 (insulin-like growth factor receptor-1) and TGF-beta (transforming growth factor-beta) signaling systems acting as major growth regulatory pathways converge on autophagy genes to control cell size. Thus, autophagy may act as a central regulatory mechanism of cell growth.


Grain Table Top Tray Sealer Industrial Vacuum Sealer Machine 304 Stainless Steel
The shelf life of food refers to the period of time during which the food can be kept relatively stable from the date of leaving the factory through various circulation links until it is in the hands of consumers. During this stage, the sensory characteristics, physical and chemical indicators and microbial content of the food are within the acceptable range, and any nutritional value declared on the label is retained.
The principle of modified atmosphere storage and fresh-keeping technology:
Oxygen accounts for 20.9% of normal atmospheric gas composition, and 0.03% for carbon dioxide, and modified atmosphere storage will change the content of oxygen and carbon dioxide in the storage environment. Among them, the content of oxygen is reduced to 2% -5%, and the content of carbon dioxide is increased to 2% -5%.
In addition to the use of low-oxygen and high-carbon dioxide gas conditions, the modified atmosphere storage and preservation technology also uses low-temperature storage. Fruits and vegetables in such a storage environment can maintain their freshness as long as possible and reduce the quality loss caused by respiration. After picking fruits and vegetables, they will still absorb oxygen from the atmospheric environment, release carbon dioxide, and produce a certain amount of water and release heat, that is, they are still breathing.
This respiration will decompose and consume nutrients in fruits and vegetables, resulting in reduced quality. To reduce the deterioration of the quality of fruits and vegetables caused by respiration, the key is to weaken their respiration and change the gas composition in the storage environment of fruits and vegetables to achieve this goal.
Ethylene can accelerate the ripening of fruits and vegetables, and is often used as a ripening agent. It is also an important reason for the post-ripening and aging of fruits and vegetables. Reducing the ethylene gas content in the storage environment can effectively delay the after-ripening and aging of fruits and vegetables, and prolong the storage time of fruits and vegetables.
The low-oxygen and high-carbon dioxide gas environment created by modified atmosphere storage can inhibit the biosynthesis of ethylene and avoid the degradation of fruits and vegetables due to ethylene accumulation. The low-oxygen, high-carbon dioxide environment and low-temperature environment under controlled atmosphere storage can also inhibit the growth of aerobic and mesophilic microorganisms, reducing the spoilage and deterioration of fruits and vegetables caused by microorganisms.
At the same time, the modified atmosphere storage environment will also inhibit the activity of certain enzymes, such as succinate dehydrogenase, cytochrome oxidase, etc., thereby delaying the degradation of fruits and vegetables caused by enzymatic reactions.
|Main focus||allow breathing, breathing will consume oxygen and produce ethylene and CO2|
|Important principle||Fast-growing products mean that more O2 needs to be breathed|
|Humidity will cause the product to deteriorate|
|Need to find the balance between breathing and mixed gas|
|High temperature will exacerbate product deterioration, high temperature = high breathing rate|
|Product name||New Type Grain Table Top Tray Sealing Machine Vacuum Packing Machine|
|Mixer configuration||Germany Witt binary adjustable mixer|
|Gas||N2 / CO2 / O2|
|Gas distribution error||＜ 1%|
|Residual oxygen per box||＜ 1.0%|
|Actual residual oxygen amount||0.3% ~ 0.0%|
|Packing box size||224 * 133 (reference)|
|Packing speed (box / hour)||200 ~ 300|
|Frame part||304 stainless steel + aluminum alloy|
|Cutter part||special stainless steel|
MAP Recommended ratio
|Preservation days (days)||Effect|
|Kiwi||3~5||1~5||93~96||0~5||150||The number of colonies does not exceed the standard, the taste is fresh, and there is no odor
Sensory appearance and bright colors
The above data comes from professional laboratory, for reference only
After sale service:
usually machine guarantee time is about 1 year. Within guarantee time.Machine breaking caused by machine itself, design defect, we are responsible for it. We can provided free charge breaking part and so on after sale service action. If machine breaking caused by operate reasons, user take responsiblity for it, we will help to maintain machine until machine working well. of course, over guarantee time, we also here for support.
We have experienced in international freight, we can do EXW , FOB , CFR, CIF , CIP , DDU business term according to you requirement, the clearance documents we provided besides commercial invoice, packing list, also can provided CO, CE certificate .
Business term and payment:
Currently, in order to protect you and us rights, we can accept 30% deposit, balance before shipping. We can do payment by alibaba trade insurance, about the payment method, T/T, LC, WU, we can discuess it according to the business.
Contact Us at Any Time


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This irresistable Fairtrade 18ct Yellow Gold ring has been cast using cuttlefish, giving it an organic finish. This process means no two rings will ever be identical making your design one-of-a-kind. Emulating the individuality of the band is a gorgeous Australian Sapphire with beautiful strong green tones, it is far from ordinary.
This ring is a size L, if that isnt your size don't let that that stop you from having your own! Drop us an email or give us a call and we can create one especially for you!

domain: design


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SIMCom won 2019 GGAI Golden Globe Award as "Annual Automotive Module Supplier"
On December 20, 2019, 2019 GGAI Annual Conference & Golden Globe Award ceremony was held in Shanghai. As a platform that focuses on the integration services of the intelligent networking supply chain of the vehicle industry, GGAI has attracted numerous industrial elites in auto driving, Internet of vehicles, intelligent cockpit, as well as leading enterprises from the traditional vehicle industry chain to attend this summit to discuss and share the significant changes and technical trends in the intelligent networking of the vehicle industry, and to predict the future of the industry in 2020.
In this summit, with its outstanding strength and innovative technology, SIMCom’s Automotive module stood out from numerous items on display and won the Golden Globe Award as "Annual Automotive Module Supplier". SIMCom has dedicated to its research on the Automotive module long time ago. SIMCom has issued its automative modules SIM7800 and SIM8100 before. SIM8100, as a C-V2X module supporting C-V2X function via PC5 interface, is applicable to such applications as vehicle to vehicle (V2V), vehicle to pedestrian (V2P) and vehicle to infrastructure (V2I) situations. At present, this module has gone through some tests and road tests, mainly to match the auto driving tests. SIMCom also launched its LTE-A+C-V2X solution - SIM7920X-Au. SIM7920X-Au Automotive module is the LTE-A+C-V2X next generation Automotive module solution based on Qualcomm SA415m platform. It uses LGA package, and supports up to LTE Cat 19 connection. Meanwhile, it also supports LTE Cat6/9/16 All-Modes network system at the same time, with a maximum downlink speed of up to 1.6Gbps. SIM7920X-Au can provide Open Linux secondary software development packages to the customers, which allows customers to develop their own functions. Meanwhile, the module is integrated with solutions that meet the vehicle network communication security requirements, and provides multiple security policy mechanisms to ensure the security of the network communication. Besides, SIM7920x-au not only reserves many peripheral interfaces, including SDIO, I2C, I2S, USB, UART, GPIO, etc., but also provides high-speed Ethernet interfaces suitable for the high-speed data transmission in the vehicle, in order to offer stable and reliable communication ability to the vehicle. In addition to 4G Uu communication ability, SIM7920X-Au supports C-V2X PC5 direct connection communication functions, which allows the low delay communication between vehicle and vehicle (V2V), vehicle and infrastructure (V2I), vehicle and pedestrian (V2P). The new generation LTE-A+C-V2X 2-in-1 vehicle module solution can meet various demands in the market of Internet of vehicles, such as auto driving and safe driving, and play an important role in the construction of intelligent transportation system. With the official commercial launch of 5G technology, the 5G+C-V2X integrated automotive grade module SIM8200X-Au will also be launched.
IHS predicted that the sales volume of the intelligent vehicles will exceed 10 million all over the world by 2035, and that the market volume of networking vehicles all over the world will achieve 350 million by 2022, with a market share of 24%, while sales volume of new networking-enabled vehicles will achieve 98 million, with a market share of 94%. With the diversification of the networking technologies and the improved networking rate of vehicles, the market potential of the Internet of vehicles service will be released gradually, and the Automotive module will embrace its next round of significant development. SIMCom will further improve its Automotive module series to keep pace with the times.
M2M Application Smart Energy Automotive Electronics Smart Payment Smart Life Security Monitoring Urban Refined Management Wireless Gateway Smart Industry Smart Agriculture


YORKSHIRE drivers are the worst in the country, says a survey.
One in six Tykes has a motoring conviction, says online car insurance search engine Confused.com
Law-abiding Northern Ireland is top of the UK league, with just 5% of people having points on their licence.
One conviction puts an average of £74.60 on insurance premiums, with two adding £182.92 and three leading to an extra £301.84.
Confused.com spokeswoman Debra Williams said: "These figures can look daunting, but it's important to realise not all insurers penalise in the same way.
"If you have points on your licence shopping around can bring back major savings."
A spokeswoman for Huddersfield-based road safety pressure group Brake said dangerous driving could end up hurting you a lot more than your pocket.
She said: "While the high level of driving convictions in Yorkshire is of real concern, risk-taking on the road brings tragedy to families across our country.
"We need drivers to put safety first every time they get behind the wheel.
"But we also need the Government to get tough with drivers who laugh in the face of the law, putting lives at risk when they drive.
"Brake is urging the Government to make road policing a priority.
"We want the Government to ensure there are enough traffic police to catch dangerous drivers and get them off our roads before they kill and maim themselves or others."


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We all know it. We speak of a courageous act.
Despite the fear we used our mind. It is possible then.
Joy overcomes fear.
We practise Zhineng Qigong, get away from our daily life.
We do it regularly.
We are looking forward to this short time during the day.
We learn to take the joy into our present day.
The positive attitude makes everything easier.
We use our mind and the fear disappears.
We confront our problems that have not gone away.

domain: literature


text:
Wings of Change
A dying dragon brings revelation of even more magical creatures than himself, and a woman that could unite them all.
Reynor is a dragon, wounded in battle and too young to deal with the guilt wracking both himself and his young knight. He crawls off to die alone but encounters a young woman who will not let him pass.
Lucia is a refugee from her own land, glad to find peace and anonymity in Draconia. When she encounters her first dragon and realizes the state he’s in, she cannot let him leave this world without at least trying to help him. Gathering her courage, she marches up to the castle Lair and demands to speak to his knight.
Sir Kaden is in deep despair about Reynor’s injury and doesn’t know what to do, or even where to find the giant dragon. When Lucia storms the castle and demands Kaden wake up and go help his partner, he realizes not only has he been given a second chance with his dragon, but he’s also met an intriguing woman who might just be his mate.
Sir Marcus agrees. Marcus is the knight partnered with Reynor’s mate, and together, the four of them make up a small family unit, only wanting one thing…a mate for the two human knights.
They find Reynor near death. Only a miracle can save him now, but Lucia might hold the key—and her love—which is the greatest miracle of all.
Yes, this story is a menage. You have been warned.
* This novella is part of the Dragon Knights series, which also includes:
The Dragon Healer
Master at Arms
The Ice Dragon
Prince of Spies
Keeper of the Flame


I'm curious cause a guy on another forums asked this question and he says he bought a 2DS from some store and upon returning home and booting it up he noticed that his 3DS's online functionality seemingly does not work. Basically, he can't update the firmware and he can't go online with it so he checked the firmware and 11.0.0-4U is what showed up. We told him to check the SD card and he says there's a lot of weird files on the card that wouldn't normally be in a clean SD card. He pretty much can't do anything about it now but to use the 3DS as an offline only console cause the firmware version he has doesn't even officially exist Sounds like a creepypasta but it's true lol Just wondering how the 3DS he bought ended up with that particular firmware version? What do you think did the original owner do with the console.


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Big Apple Cider Trials took place in Putley over the Bank
Holiday weekend and cider makers from Ross Cider & Perry
Co were delighted with their results. Proprietor of Ross
Cider, Mike Johnson not only won first place with his medium
dry cider, which I hasten to add is really delicious, he
was placed third with his dry perry and then judged overall
champion of the event.
Edwards also did well at the Big Apple event. Last year,
John's dry perry was placed second, but he bettered that
this year by winning first place. Well done John! The good
news didn't stop there however, as Gabe Cook was awarded
second place for his medium dry cider and third place for
the dry cider. Not bad at all for somebody who has only
been making his own cider for three years.
is the fourth time in the nine years that the Big Apple
has been running that the beautiful trophy has been awarded
to Ross Cider & Perry CO and we went along to Broome
Farm to congratulate the winners and talk to them about
their achievements. You can see what they had to say in
the WNTV News sequence below.

domain: news


Describe your blog/channel and what it’s all about:
I mainly just document my life really. My blog mainly branches into anything lifestyle and travel related. But, I also cover various other areas including beauty, university life, food, and theatre. Just a bit of everything really.
When did you begin blogging/vlogging and how did it all start?
Having a blog was something I’d thought about for a long time, especially having followed bloggers and vloggers for years. A friend of a friend had a blog and I just thought what is actually stopping me from doing this for myself, so I just went and made one. Wow, was it a shock though. Unless you’re a blogger, you completely underestimate how complicated the whole process can be at first. But, it was worth it and I love blogging. I’m so happy I made the little spontaneous decision to just do it and not care what others thought!
Is there anything you wish you had known before you started?
Like previously mentioned, how much truly goes into blogging. At the face of it yes it just seems like a bit of writing and some photos to go alongside it. BUT, there’s a whole wealth of tricky little bits like SEO, sharing, plugins and widgets that need to be optimised to make your blog run.
Any tips for anyone interested in starting up their own blog or vlog channel?
JUST DO IT! I am so proud of how much I’ve learnt, the people I’ve met, and what opportunities blogging has given me. All the overthinking and fear of judgement has been completely thrown out of the window. Over the last two years my confidence in my blog has grown massively, to a point where I am happy to share my blog with people in the ‘real’ world and not just the ‘internet’ world. You definitely won’t regret it.
The best thing about blogging/vlogging:
Oh, it has to be the people and of course the York Bloggers community. I wouldn’t have met these people if it hadn’t been for blogging and these ‘internet friends’ are just as true as my ‘real’ friends. I just wish we were able to see one another more. They support, inspire and are truly amazing, and I love seeing them do bigger and better things with their brands, businesses and blogs/Youtube channels!
What’s the thing you find most challenging about blogging/vlogging/influencer marketing to date?
SEO. Sorry, like what!? Only after buying my own domain and going self-hosted did I start to see the true complicated nature of blogging. I am still learning new things all the time, but I’m getting there.
Have done any cool reviews/attended any awesome events recently? If so, what?
Tell us about your favourite post/video you’ve worked on?
My favourite posts generally are my travel posts, simply because I appreciate the opportunities to go abroad and see new places so much. I’m currently working on my Iceland Travel Diary series, where I talk through what we did each day whilst out in Iceland earlier in the year. I love looking back through the photos and seeing how truly beautiful Iceland is. If you want to give the series a read, click here to be redirected. As well of this, I’m excited to document the next new chapter in my life, which involves a big move to the UAE.


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Great Basin Community Food Co-Op
Italian Hearts Pasta Sauce
acres in Gardnerville, NV
65 miles to market
60 miles as the crow flies
We started our company in 2012, we have grown enough to own all of our own commercial kitchen equipment. At one point we have a staff of 15. Since then we have decided to scale back and focus more on Local. And Papa Sal & Val have taken back our own production of our sauces. We have also opened up our commercial kitchen to other Food Producers so they can have a Hub Kitchen to work from. Our focal is small and handcrafted foods.
Our goal is to cook so you don’t have to bring to the Marketplace Italian Red Sauces that are made exactly as we cook from home, low and slow in small handcrafted batches using good healthy local ingredients. Our 3 Red Sauces have been passed down from many generations. Italian’s Red Sauce is a key to good health, we use our Red Sauces for everything pasta and much more! With love from our Italian Hearts to Yours.


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Author: Carli Gardner
At Glendon, researchers’ multidisciplinary and interdisciplinary approaches to complex problems provide solutions to current issues. In the context of COVID-19, we can see how the Social Sciences and Humanities are important to identify and unpack the societal effects of the pandemic, beyond the biomedical concerns.
Glendon researchers, Dr. Gertrude Mianda and Dr. Shirin Shahrokni each conduct research in separate disciplines to explore the effects of systemic racism and discrimination on specific racial groups in Canada.
Mianda is a full professor in Glendon’s Gender and Women’s Studies program who focuses her research on the experiences of discrimination lived by francophone immigrants from Sub-Saharan Africa in Canada. The current director of The Harriet Tubman Institute for Research on Africa and its Diasporas at York University, Mianda works to expand the Institute’s membership to include francophones belonging to both African and West Indian communities.
Shahrokni is an assistant professor of sociology at Glendon. She is the Principal Investigator of a SSHRC-funded research project on the socio-professional trajectories and experiences of francophone immigrants in Toronto, through critical race and feminist perspectives. Shahrokni is also the co-investigator of a SSHRC-funded research project titled the “Racialization of Asian International Students” (RAIS) (Principal Investigator: Dr. Jean Michel Montsion). The project investigates the racialization experiences of international Asian students across five Canadian universities.
Though distinct in their research initiatives, Mianda’s and Shahrokni’s central concerns with the impacts of discrimination on racial groups provide insights and research data relevant to better understanding the disproportionate effects of COVID-19 on racialized populations.
On the issue of equity in access to housing, health care, and employment, Mianda and Shahrokni acknowledge that COVID-19 has reinforced the presence of deep divides in social structures among racial and non-racial groups.
“COVID-19 has exposed white privilege and the marginalization of racialized individuals in the West,” says Mianda.
In her research studying the experiences of francophone immigrants from Sub-Saharan Africa in Canada, Mianda exposes how systemic discrimination of this racial group leads to their overrepresentation in low income employment.
Mianda explains that because immigrants from Sub-Saharan Africa are members of Canada’s Black population, a group marginalized by structural inequities, their place in front-line positions at the bottom of the occupational scale increases their likelihood of exposure and infection to COVID-19.
Like Mianda’s, Shahrokni’s research aims to highlight the mechanisms that produce racial inequalities across mainstream institutions and their effects on racialized individuals.
In the context of COVID-19, Shahrokni’s research provides relevant information about structural inequalities to understand specific challenges the pandemic presents to various racial groups.
Shahrokni points out that without recognizing the different effects of COVID-19 on racialized communities, inadequate one-size-fits-all solutions to challenges in housing, in employment and healthcare are proposed.
“We obviously have all been hearing and repeating to one another that we should ‘stay home’,” Shahrokni said, “It seems simple, effortless, but the ability to ‘stay home’ for a prolonged period with limited outdoor activities is not readily accessible to all of us.”
Shahrokni continues to outline inequities in social structures by highlighting the disparities in access to health care for racialized groups and Indigenous people. She also explains that while the issue of accessibility obviously heightens the impact of COVID-19 on these communities, the sense of distrust among their members vis-à vis the health care system is also a significant factor.
“Because of repeated experiences of racism within the health care system […],” Shahrokni says, “many members of racialized and Indigenous communities will tend to distrust and avoid recourse to the health care system even if their medical conditions require assistance.”
Without a discussion of the different impacts of COVID-19 on various racial groups, there is a failure to recognize the continued existence of systemic inequalities in contemporary society, and the lack of statistical data on race in Ontario plays a major role in this.
Mianda’s and Shahrokni’s various scholarly contributions on systemic discrimination in Canada further highlight the structural inequalities experienced by racialized individuals and communities, reminding us how such discrimination is exacerbated and dangerous in times of crisis.
The Research and Innovation Office is proud to support and to promote Dr. Mianda’s and Dr. Shahrokni’s important research programs on issues of racial discrimination in Canada that engage us all in ensuring an equitable and inclusive educational society.

domain: sociology


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This usurpation of voters choices for elected office is taking place in all Republican dominated state governments. Republicans are trying to add to the powers they put in place to limit or discourage voter participation by short circuiting officials voters other than Republicans have put in office by removing them from office with made up charges or excuses or short ciruiting their ability to perform official duties.
Florida’s DeSantis led the charge in taking his state towards its descent into fascism. He removed a Tampa area prosecutor who didn’t fully embrace his bullying tactics at members of the LGBTQ community by alleging Andrew Warren had blanket policies not to prosecute certain kinds of cases. The federal judge ruling on Warren’s dismisal stated categorically that allegation was false but he also declared ‘the Eleventh Amendment prohibits a federal court from awarding declaratory or injunctive relief of the kind at issue against a state official based only on a violation of state law’. With that victory in hand for now DeSantis has set his sights on State Attorney Monique Worrell because of her handling of a case. The particulars aren’t important, the idea is DeSantis can go after anyone within his reach and for any reason and doing so establishes his bona fides as the non-woke, hard nosed, more attractive and polished MAGA candidate for the Republican party.
Florida isn’t the only state that’s decided to circumvent its voters choices to run constituent business. Mississippi has decided to go around an entire administration of its capital city and replace it with governor Tate Reeves’ own Capital Police Force that has been given the expanded responsibility of policing neighborhoods in Jackson. That police force has been accused of excessive brutality towards black citizens of Jackson while patrolling the streets in and around government buildings. Along with this special group of police the GOP run Mississippi state government has also put in place an extra judiciary arm of judges super imposed over the city’s court system designed to adjudicate cases that would give the GOP ability to determine outcomes. All of these reaches from the halls of state government into city government have placed at the disposal some of the city’s financial resources that Jackson has received from the federal government, like the nearly $800 million in federal and other aid Jackson city Mayor Lumumba secured to fix the dilapidated water system the city has been suffering with for almost a century. These changes to the structure of a city that is 80% black and done by a super majority of GOP politicians of the state’s legislature have been done without input from or the ability of the elected officials of Jackson to change. They have simply been presented to them as the way things will be.
For now perhaps the most popular example of the GOP subversion of democratic processes is what happened in Tennessee with the Tennessee Three. The three state legislators were considered for expulsion from the Tennessee state legislature because of their action depicted in the photo below but just a brief history of what goes on in the legislature, as shown in the following video, clearly reveals Tennessee has a Republican majority not interested in following the rules, even those they propose or use.
Recognize any faces in the piece? Is it any wonder the three legislators took to the well of the House with a bullhorn to raise their voices after so many times having their voices ignored or not listened to during the course of conducting state business the ‘correct’ way? An even more blatant sign of the state of democracy in Tennessee is that while three legislators were threatened with expulsion, only two of them, Jones and Pearson were actually expelled. Their expulsion wasn’t based on their adoption of some excessive progressive agenda, antithetical policy foreign to their constituents. Rather theirs was a locally supported and embraced set of goals designed to enhance participation in the political process for all citizens of the state with their last stated goal being to enact some form of common sense gun legislation following the mass shooting and murder of students and staff at a local private school. That type of activism is not acceptable to a majority GOP legislature that only sees the imposition of unpopular policies as the way to success in participatory democracy. The state of Tennessee has threatened to withhold money appropriated to those municipalities that consider returning those expelled lawmakers to office.
Finally these are not the only examples of an out of control Republican party with fascist tendencies to spread policies that are directly opposed by a majority of the constituents of the state. Super majority legislatures are possible because of gerrymandering, the act of drawing voting districts that dilute the effectiveness of non Republican precincts and increase the number of GOP candidates elected to office even while they are a minority within a state’s population. One of the most egregious legacies of the Trump term was its abuse of 2020 census data released by the federal govt as well as a Supreme Court 2019 decision that said gerrymandering for party advantage cannot be challenged in federal court. With no threat to the way voting maps are drawn to increase their presence in state legislatures, Republicans have the ability to act without any regard to what the people of their states want. By electing officials to state office, the Republican party is able to form policy that suits the needs of party officials and lobbyists who support them financially but which are at the same time not in the best interest of the people of the state.

domain: law


McLaren probably shouldn’t be allowed to sell this car to regular people. But it does. State authorities probably should set up some sort of tiered licensing system, whereby people who want to drive a thinly disguised race car on public thoroughfares will need a bit of extra training and certification. But they don’t. Instead, the only skill a person needs to drive one of these psycho death-missiles on the street is the ability to earn (or inherit) tons of money.
This story originally appeared in Volume 3 of Road & Track.
It’s called the 765LT, and it’s way over the line. Not that this development should come as a surprise to anyone. McLaren’s previous foray into the way-too-fast-for-the-street realm, the Senna, was a bit more extreme and significantly weirder looking than the 765LT. The problem with the Senna—if anything in the rarefied world of a $1 million-plus track-day special with see-through doors could be considered a problem—is that except for a few very select places, say, a Hermann Tilke-designed F1 circuit, the standard 720S is just as fast, for a quarter the cost.
The 720S is the car from which the Senna and the 765LT descend. And three years after its debut, the 720S remains a supercar game changer. Last year I took a comfort-spec 720S Spider to a track day at Auto Club Speedway in Fontana, California. It wore street tires, regular wheels, and cushy seats. I’m an average, club-level driver, but armed with the heaviest, most comfort-oriented version of 720S, I had a track-day cheat code that allowed me to make literally any pass I desired. It needs none of the additional track-day goodies offered by McLaren Special Operations (MSO). Like, at all.
But McLaren, doing the thing that McLaren does, pushed the limits of the 720 platform’s performance, both for pride and for profit. The result is the 765LT, a device whose accelerator pedal carries a 1:1 ratio of pressure to poo-extraction. I can confidently say that this is the quickest production vehicle I have ever driven, by a noticeable margin. Just take one metric, quoted from McLaren’s press release: In a 0-124 mph acceleration test, the 765LT is 1.6 seconds quicker than the Lamborghini Aventador SVJ, 1.4 seconds quicker than a Porsche 911 GT2 RS, and 0.6 seconds quicker than a Ferrari 488 Pista or a McLaren 720S. Yowza. Those are enormous gaps compared to some of the world’s quickest production vehicles. And typically, McLaren’s performance estimates are a little conservative. Similarly, McLaren says the 765LT makes 755 hp and 590 lb-ft-of torque. I say this number is quoted at the wheels on a hot day. It’s likely closer to 800 hp in cool, California fall conditions. Compared to the standard 720S, the 765LT’s twin-turbo 4.0-liter V-8 has upgraded pistons, gaskets, a more powerful fuel system, and a new tune. But it also has its own shorter gear set, which means in-gear acceleration is improved 15 percent compared to the 720S, a car that needed absolutely no help in that department, whatsoever.
In McLaren-ese, “LT” is an abbreviation for “Longtail.” It’s meant to call to mind the 1997 McLaren F1 GTR Longtail race cars that amped up the already amply amped F1 GTR with stretched bodywork, a bigger rear wing, and a sequential-shift transmission. But the LT badge is a misnomer. Truth is, the only added length is from extended front splitters and rear wings. When applied to the 765, or the two other recent McLarens that have worn the LT badge, it actually means: lighter, faster, angrier, and more engaging. But an LFAME badge would be too heavy.
The LT line is the company’s factory performance custom series. Nothing has been left alone. Virtually every body panel, save for the windshield and roof, has been either changed or materially replaced, compared with the 720S.
The 765LT is the first McLaren to feature carbon-fiber body panels created in-house. And what a body it is. The 720’s lines are as smooth as river rock. But the LT’s are jagged and aggressive with exaggerated skirts, jutting jaw, various vertical aerodynamic fences, and raspy-looking louvers atop the front fenders.
The entire backlight assembly, four individual pieces, is now made of polycarbonate. The exhaust is titanium and 40 percent lighter than the one used in the 720S, with four tips. Most interior surfaces, including the two seats, are sculpted carbon-fiber panels. The wheels are lighter and affixed to the car with titanium bolts.
By default, McLaren deletes both air conditioning and the stereo, but they are no-cost options to add back. Without them, the LT is lighter than the standard 720S by 176 pounds. But since the Venn diagram of “People who spend $400,000 on cars” and “People who are willing to not have air conditioning in their $400,000 cars” is just two circles near each other, most 765LTs will sit at the curb only 151 pounds lighter than Mr. Jones’s 720.
The LT’s brakes come directly from the Senna, and are, ironically, 10 pounds heavier than the standard 720S brakes. According to McLaren, the performance improvement is worth the heft. The 765LT also brings specific shock calibration.
The 720S delivers impressive grip from standard Pirelli P Zero tires. Naturally then, the 765LT comes with Pirelli P Zero Trofeo Rs, a barely legal street slick that requires some heat before delivering anything resembling grip. They also throw a shocking amount of gravel and road grime into the door assembly, which tumbles down like a souvenir-store rain stick when you open the door at the Mastro’s valet.
After a short, 4-5 mile warm up, I pointed the 765LT down a highway at a reasonable speed, manually engaged third gear, and stomped the go pedal. It absolutely blew the tires right off, even with traction control fully enabled. Rather than lift, I upshifted, and the burnout continued well past 100 mph. Even crossing 110, 120, the 765LT fought for traction. That’s just not the kind of thing you see from a mid-engine production car. I did it again, rolling on the power in third gear, and at 90 mph it stepped sideways a bit before straightening out and continuing to spin its rear tires and fight traction well into the middle of fourth. Welcome to crazytown.
I took my wife out in the 765LT and, upon merging onto an entrance ramp, floored it in fourth gear. She immediately got nauseated and told me never to do that again. I took a friend out for a quick spin. He turned ghost-white and, sensing the fourth-gear wheelspin, promptly echoed my rhetorical question back to me: “They just sell this thing to people? What are they, nuts?”
The performance of this vehicle, even to a jaded man such as myself, is beyond anything folks should be able to just buy and drive on the street. I went to the biggest, fastest, emptiest road in Southern California, just after sunrise, and drove basically as fast as the 765LT, and my nerves, would allow. Even after 12 minutes of highly focused, sweaty-palm, heavy-breath driving, ol’ Macca’s tire temp indicators showed BLUE. I had just gone up this hill as fast or faster than I ever had and even that was not enough pace to warm up the tires in this thing.
Even if the tires won’t come up to temp, the handling is telepathic and the steering is chattery, alive. And, my God, the brakes are spectacular. The intelligent active Air Brake system, which flips the spoiler to near vertical, makes the 765LT unbelievably stable while shedding speed. And it doesn’t even require that you tap the pedal to activate. A quick lift off the throttle after hard acceleration will kick the Air Brake into action, stabilizing the rear end as weight shifts forward. It’s brilliant.
There isn’t a public road anywhere on the entire planet on which you can safely approach the performance limits of this car. And while that’s likely true of the 720S as well, the differences in execution are stark. The 720S shines not only because of its performance, but because of its flexibility and comfort. It is, in the grand scheme, the more impressive accomplishment.
With the LT, the focus is narrowed. Dialing up the motorsport theater diminishes the usability of the car. The hard carbon bucket seats leave bruises after a day of casual trundling. The harsh suspension is by no means unbearable; it’s now in line with the ride quality of the Lamborghini Huracan Performante, but the “magic carpet ride” of the 720 is absent. In four days, I didn’t move the chassis knob from Comfort for more than five seconds. For the 765LT, McLaren relaxes some of the powertrain NVH attenuations that make the 720S so livable. The stiffer engine mounts and bushings mean that more vibrations find their way into the cabin. That sounds good at first, but over the course of a couple hours’ drive it adds up. It’s a level of intensity best experienced in small, glorious doses.
I leave with the utmost respect for this car. The 765LT delivers, absolutely and unequivocally, on everything it promises. Its performance is simply staggering. Sure, $433,000 (as tested) is a seriously high price tag, and for that money, it had better do everything but tie your shoes for you. But, to get anything faster, or even as fast, you’d have to spend between six and 10 times as much. It is typically the nature of custom-built cars that their areas of specialization narrow, but also deepen. Such is the case with the 765LT. It gives up some of the 720’s balance in favor of intensifying some of that car’s already intense characteristics. But we can appreciate a car with a range of talent that’s spread a mile deep and an inch wide. The 765LT is the best pseudo-race car for the street that McLaren has ever made. It’s the best of the LTs.
How McLaren turns the 720S into a 765LT, by Mack Hogan
Trimming 176 pounds from the already featherweight 720S required detail work that borders on the absurd. Perhaps most absurd is the deletion of the air-conditioning and audio systems. Don’t worry. Adding them back is a no-cost option that everyone will get. Also in the absurd column are carbon-fiber interior trim surrounds. But there are meaningful efforts, too. Ten-spoke forged alloy wheels with titanium bolts trim 48.5 pounds from the car (the optional big brakes add some of that back). The 765LT’s seats are 39.7 pounds lighter than the 720’s buckets. Masochists can opt for the super-lightweight carbon-fiber racing seats, which were standard on the Senna and trim another 26.5 pounds. The titanium exhaust system shaves 8.3 pounds compared to the 720S. And a new lithium-ion battery sheds 6.6 pounds. But that’s not all. Buyers can also opt to swap out the aluminum hood, doors, and rear fenders for lighter carbon-fiber pieces. All 765LTs have thinner window and windshield glass plus polycarbonate rear windows. McLaren also strips out the 765LT’s carpet and uses a manually adjustable steering column. Point is: Go ahead and have that second pastrami sandwich.
A front end that sits 5 mm lower gives the 765LT a bit more rake. The 765 uses lightweight main springs at each corner plus small helper springs. This reduces unsprung mass compared to larger dual-rate springs. Those springs are stiffer compared to the 720S. The 765LT retains the familiar linked hydraulic dampers from earlier Super Series McLarens, but these are now controlled by new software algorithms that deliver greater precision and control, says McLaren. The 765LT trades the 720S’s Pirelli summer tires for hyper-aggressive Pirelli P Zero Trofeo R track tires. Common side effects of this treatment include compromised ride quality and non-existent wet-weather traction.
It wouldn’t be an LT without a power bump. There’s an additional 45 hp from the twin-turbo 4.0-liter V-8, which brings the total to 755 hp. And it’s a screamer, too; that peak power hits at 7500 rpm, 500 higher than in the 720S. Maximum torque still arrives at 5500 rpm, but now totals 590 lb-ft instead of 568. Much of the increase comes from a 1.7-psi boost in turbo pressure, but the 765LT also benefits from a healthy injection of Senna. The LT gets lighter forged aluminum pistons, a three-layer head gasket, and a second fuel pump from the alien-looking hypercar.
It might not be designed for the Mulsanne Straight like the original Longtail race car, but the 765LT produces 25 percent more downforce than the 720S, according to McLaren. That’s thanks largely to the protruding front splitter, a longer diffuser, and an articulating rear wing  that, even while retracted, stands taller than the 720’s. Other aero doodads, such as the “door blades”  and redesigned floor, contribute as well. All that downforce means the 765LT’s top speed is a piddling 205 mph, down from 212 on the 720. Factor that into your work-commute ETA. McLaren also redirects air to keep the front brake pads 50 degrees cooler.
Whence it Came: McLaren Longtails
By Chris Perkins.
A. F1 GT/GTR “Longtail” (1997): The F1 GTR dominated GT1-class racing in the mid-Nineties, winning Le Mans in 1995 and the BPR Global GT Championship in 1995 and 1996. Not originally intended to be a race car, the F1 was perfect for the production-based regulations. Then, in 1997, Porsche created the 911 GT1, a mid-engine prototype with a handful of road cars made to homologate it for the FIA GT Championship. “Porsche built a racing car and forced us to do it,” McLaren designer Gordon Murray said in Driving Ambition. In 1996, Murray sketched what became the Longtail. The new car was 22 inches longer than earlier GTRs to increase downforce. McLaren built 10 race cars and three F1 GT road cars to satisfy homologation requirements. McLaren’s 1997 entries, run primarily by BMW Motorsport, won five races. But AMG won the remaining six with the radical CLK GTR, giving Mercedes the championship.
B. 675LT (2016-2017): For its more track-focused version of the 650S, McLaren Automotive resurrected the Longtail moniker and built a car spectacular enough that you could forget it had nothing to do with the original Longtails. In fact, the 675LT was only 1.5 inches longer than the 650S. Hardly a Longtail, then. But it was nearly 300 pounds lighter than the base car. Numerous aerodynamic tweaks generated more downforce, and McLaren extracted 25 additional horsepower from its 3.8-liter twin-turbo V-8, for 666 in total. This was a watershed car for the modern McLaren Automotive, the car that showed the company was fully capable of beating Ferrari at its own game. McLaren sold 500 675LT coupes worldwide, and 500 675LT Spiders in 2016 and 2017. The 675LT was such a critical and commercial success for McLaren that the company decided it would continue making hardcore LT variants.
c. 600LT (2018-2020): The second modern LT applied the formula to the entry-level 570S. Compared to the base model, the 600LT was 212 pounds lighter, had 30 more horsepower, a stiffer suspension, ultra-sticky tires, more downforce, and a length increase of three inches. Oh, it also had top-mounted exhaust outlets that shot flames. Once again, there were coupe and Spider versions of the new LT, with the drop-top weighing 110 pounds more than its fixed-roof counterpart but no less excellent to drive. The 675LT was a tough act to follow, but the 600LT lived up to the Longtail name with a thrilling driving experience and performance that kept even the 720S honest. McLaren built more 600LTs than 675s, but the company won’t reveal sales figures, though it says fewer than 500 coupes and 500 Spiders made it to the U.S. While it’s the most common Longtail, a 600LT is still a rare sight.


text: Little Mermaid Theme - Here's a creative way to make reusable Little Mermaid Party Cups into beautiful, fun favors. Fill it with lovely favors like Little Mermaid Crayons, Bounce Balls, Pencils, Sharpeners, Erasers, and Notepads. We also think Ariel would like these sea-anemone-looking Squishy Rings. Your cup will be picture perfect if you start by lining cups with Lime Green Crinkle Paper Shred. Slip each cup inside a Clear Party Bag and tie it closed with Turquoise Curling Ribbon.


April 4, 2013 at 1:12 PM ET
Debuting her new song "Grown Woman" in a glitzy new Pepsi commercial, Beyoncé takes a look in the mirror -- and likes what she sees.
And why not? The bevy of beautiful babes are all reflections of the pop superstar's younger personas, from Destiny's Child to Sasha Fierce.
Her identical backup dancers all gyrate in their signature looks from each Beyoncé era: "Bootylicious" pink, the "Crazy in Love" white tank top and denim shorts, and "Single Ladies" black leotard.
Now the 31-year-old superstar really is a "grown woman": She and hubby Jay-Z recently celebrated their daughter Blue Ivy's first birthday.
"Embrace your past, but live for now," smiles Queen Bey, as the mirror shatters behind her.
What do you think of Beyoncé's new promo? Tell us on our Facebook page!


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Firms are required by law to report breaches within 72 hours
The Information Commissioner’s Office (ICO) is assessing information provided to it by Ardonagh after the broker was hit by a cyber attack last week.
The breach - described by The Register as a ransomware attack - was announced by Ardonagh on 30 September. The incident ”caused disruption across a limited part of the Ardonagh Group estate”, the company said last week.
Businesses affected by cyber attacks are required to notify the ICO within 72 hours when there has been a data breach. In serious cases, those affected must be contacted also.
Ardonagh said the incident was identified as a result of the routine comprehensive monitoring it has in place.
”We immediately took all necessary action including taking impacted systems offline and have implemented our business continuity plans in the impacted business units, to minimise disruption to our customers, Ardonagh continued.
”We are working with third-party forensic and IT experts to manage the situation and are in the process of carrying out remedial action.”