text:
This is one of several pages of original poetry, prose and reflection by this author which comment on many aspects of the human condition
N.B: Please note, all my articles are best read on desktops and laptops
These short pieces are my reflections on the subject of love.
Some of these will be very personal truths for me, some have a basis in truth in my life, and some possibly have only a little truth in my life.
I can relate to all of the sentiments, but I cannot at this time say which are most personal to me.
I hope though that all may strike a personal chord with someone.
It has been a pleasure to write them.
How sweet the innocence of youth and the immense passion of first love.
The belief that love is all that matters. The belief in fairy-tale romance. The belief that love conquers all...
A belief that all too often fades with age, and is extinguished, as harsh realities set in and the daily grind of living becomes ascendant, and the romance is then forgotten and loving together becomes just living together and existing together.
But I still believe...
40 years on.
THE TOUCH OF LOVE
How strange the touch of love...
The touch of the skin of a billion people would stir no emotion, no feeling, no sense of desire, no passion.
The touch of the skin of the one I love feels softer and gentler than the finest silk, and more comforting too. And lips; to touch our lips together; how such a simple touch can pump the adrenalin and make the heart beat faster, is something no science can explain.
How strange the touch of love.
THE NEVER ENDING LOVE
The emotion, the tugging at the heart, the bond stayed firm, the man and the woman together in the field. Nothing could take away the strength and the depth of the feeling.
The bond between them would never be broken. She knew that. There among the grass under the shade of the old oak tree, she knew the love would live forever.
The tears poured as she laid the flowers on his grave.
THE EMOTION OF LOVE
An all-consuming emotion. An emotion which can block the mind to rationality, an emotion which can blind the eye to ugliness, an emotion which can deafen the ear to evil words. It lightens the heart more than the lightest of good humours, it stirs the tears more than the deepest pain, and when it is betrayed, it can create bitterness deeper than the most intense anger.
That is love.
THE DEEPEST LOVE
She doted on him. In her eyes he was the most special man in all the world. He was the man who could do no wrong. He was the man who had the brightest future, the nicest smile. He was all she lived for, all she thought of. She would have done anything for him. And did. Oh, others would come into his life and love would grow again, and any new love would be of a very very different kind, and maybe this new love would grow deeper than his love for her.
But the love which any other person felt for him would never be as deep as the love he experienced from her.
And he knew it, but he knew it too late to say thank you. Saying thank you when she is no longer there is too late.
Thank you mum.
The following is taken from one of my other pages - a compilation of short stories each of exactly 50 words. The clue is in the title - this piece is exactly 50 words in length.
With love, my mother gave birth and nurtured me.
With love, my girlfriend stared into my eyes, squealing ‘Yes!’ to my proposal.
With love, my children laughed and squeezed my hand and needed me so much.
With love, my friends mourned my passing.
What love! The measure of my success.
Her love was clear and focused. She came from a poor background in a poor country. He came from a rich background in a rich country.
Her love was deep and true and and it was certain. And she had so much love to give.
First for his passport, second for his wallet, third for him.
LOST LOVE RETAINED
Is there anything which is worse than a relationship which still remains, when all the love in that relationship has been lost?
Yes there is;
There is a relationship which has been lost, when all the love in that relationship still remains.
Each time she strolled past him she smiled, and continued on her way, forgetting the moment. Oblivious.
And each time he smiled back, and consumed in his own fantasies, he watched her go.
Some times she'd briefly chat with her acquaintance, before continuing with her day, forgetting the moment. Oblivious.
And each time he would cherish those moments and how he wished he had the courage to tell her the things he wanted to tell her.
Then one day she left and never returned. Oblivious to what she had left behind.
And he would always wonder. What ever became of her? And what might have been, if only .....
There is a hole that exists. A hole that is deeper than the deepest well, deeper than the deepest mine, deeper than the greatest chasm. And it is darker, more empty, more hollow.
Emptiness and hollowness can be relative terms. A hole which has always been a hole is no more empty today than it has ever been.
But where once there was solidity and warmth and fullness, if now there is vacuum and coldness and emptiness, then this is when the hole feels deepest, and the emptiness and the hollowness are most acute.
Today the hole is in my heart. And it is the deepest, most empty, hollowest hole in all the world.
And it can never be filled again.
Thank You for Reading this Page
I'D LOVE TO KNOW WHICH OF THESE REFLECTIONS YOU LIKE THE BEST...
Please feel free to quote limited text from this article on condition that an active link back to this page is included
My Other Creative Pages ...
- 50 Word Mini-Stories; A Creative Writing Exercise
A number of years ago the Daily Telegraph newspaper ran a competition to write a story or essay in exactly 50 words - not one more, not one less. In this page I publish a few of my 50 word essays.
- Reflections on Loneliness and Depression
This is a page which explores through some short essays the emotions and behaviours which accompany the clinical state of depression, and also one of its most prevalent and pernicious causative factors - the experience of loneliness
- Reflections on Beauty
They say 'Beauty is in the eye of the beholder'. In this collection of poetry, prose, sentiments and reminiscences, I am the beholder, and these are my thoughts on the subject of beauty and what it means to me
- Reflections on a Lost Relationship
These are xpressions of emotion composed in the first two weeks after the end of a relationship, and reflections of the thoughts which flitted through my head.
All My Other Pages ...
- Greensleeves Hubs on HubPages
As an Internet writer I have written articles on many subjects including science and history, politics and philosophy, film reviews and travel guides, as well as poems and stories. All can be accessed here
© 2011 Greensleeves Hubs
I'd Love to Hear Your Comments. Thanks, Alun
Greensleeves Hubs (author) from Essex, UK on December 13, 2018:
Thank you Yanglish. How true!
Yanglish on April 20, 2016:
When we fall in love our reason does not prevail. Things are complicated because we cannot always translate feelings into words.
Greensleeves Hubs (author) from Essex, UK on April 05, 2016:
CatherineGiordano; Thank you Catherine very much for that. I appreciate your nice words. Absolutely agree about love and melancholy. They are like two sides of the same coin; it is difficult perhaps to have love without at some stage experiencing the reverse emotion, whether through rejection or bereavement. But of course when love is true and lasting, it can be worth all the heartache which may on occasion accompany it. Cheers again, Alun
Catherine Giordano from Orlando Florida on April 04, 2016:
Your writing is so poetic as befits the subject matter--love. Most of your stories are tinged with a bit of melancholy--again as befits the subject. Love is so often entwined with sadness because there is always the loss of love. Very beautiful little essays.
Greensleeves Hubs (author) from Essex, UK on December 08, 2014:
techygran; Thank you so much for that wonderful comment Cynthia. Your words touched me because creative writing comes from the heart and it's all the more rewarding therefore, when it is appreciated.
Most of the essays are based at least in part on personal experience and notably so, the piece you single out. We all have regrets don't we, about things we should have said to loved ones when they were alive, and I am no exception. There are things I should have said to my mother.
Thanks for the votes and shares Cynthia. Very much appreciated. Alun
Cynthia Zirkwitz from Vancouver Island, Canada on December 07, 2014:
I'm not sure why, but I was knocked off balance in reading these reflections on love-- I believe it may have been because I often come across poetic licence that has expired or perhaps was given out by mistake, but yours is the real thing that I remember from studying poetry long ago at University. Each piece revealed something surprising, a true feat in the time of the Internet and its proliferation of reflections and quotations ad nauseum. I was most touched by the reflection on "Mum," perhaps because I had been recently thinking along another track about my relationship to one of my sons and was reminded that, yes, my feelings for him do run very deep. Voted up, beautiful, interesting, pinned, tweeted, and shared...
Greensleeves Hubs (author) from Essex, UK on September 19, 2011:
Thankyou so much acaetnna for your very nice comments (dare I say, lovely comments!)It does the confidence of a would-be writer good to receive such a response. So thanks again, and glad you liked it.
acaetnna from Guildford on September 19, 2011:
I so love being in love and being loved, it is the most remarkable experience. I love this article. Brilliant in fact. Voting up and pressing your buttons too.
Greensleeves Hubs (author) from Essex, UK on August 10, 2011:
Thank you injurycase / Carol for sharing your thoughts and experiences. A lot of the inspiration for 'First Love' came from my experience when I was young, and much too shy to form a relationship. Later on I got over a lot of the shyness, but when looking for a relationship I didn't want a 'mature' and 'sensible' relationship - I wanted to have the passionate experience I'd missed out on when young.
By the way, I see you've only recently joined - welcome to HubPages. I hope you enjoy reading and writing on these pages!
injurycase from North Pearl Street, Albany, New York on August 09, 2011:
How nice that you have collected those valuable emotions that you have. After reading you hub, I reminisce those days that I fell inlove to a guy but sad to say, it didn't work for a long time. Maybe that was my minds' curiosity to experience a teenage term "first love". Anyway that was great feeling of having acquainted to the man I loved before. Thank you so much for making me realize again how colorful to be inlove.
Greensleeves Hubs (author) from Essex, UK on August 09, 2011:
Thank you prairieprincess for your lovely comment. I'm so pleased you liked these pieces. Some took quite a bit of effort to get right, but several just flowed naturally and only required a little fine tuning with the words, because they did come from the heart, and from my own experiences of life and love. It's nice when other people can understand and share these kind of sentiments which I have.
Sharilee Swaity from Canada on August 09, 2011:
Greensleeves, these are so, so beautiful! I loved reading these ... so moving and tender. Thank you for sharing!
Greensleeves Hubs (author) from Essex, UK on August 04, 2011:
Thanks d.william. There have been a few 'if only...' moments in my life, including the first girl I ever really fell for, so that story is certainly one of those which is close to my own heart.
d.william from Somewhere in the south on August 04, 2011:
Beautifully done. One can always tell by their writings on the subject of love whether they (the author) actually experienced it or just imagined how it should, or would be, "if only-".
And yet, there are those who would dare to judge another by whom they love? Talk about oblivious! Good job.
Greensleeves Hubs (author) from Essex, UK on August 04, 2011:
Thank you to both Shymyrika and Seeker7. Certainly 'True Love' isn't the most romantic, Shymyrika, but you're right; it does happen, but it is very understandable why it happens (I know from experience!) Seeker7, I'm glad 'Never ending Love' touched you. All stories about love should touch someone - perhaps especially the sad ones.
Helen Murphy Howell from Fife, Scotland on August 04, 2011:
It was very difficult to choose a favourite from the many beautiful words here. But for me the 'Never ending Love' touched me the most. Many thanks for sharing.
Myrika from Phillippines on August 04, 2011:
I like the True Love. It is cute! :) It happens.
Greensleeves Hubs (author) from Essex, UK on August 03, 2011:
Thanks Rob for reading, and for commenting and voting in the poll. I always worry about publishing creative (and heartfelt) writing of this kind, and how it will be received by other people, so I'm glad you liked it.
Rob from Oviedo, FL on August 03, 2011:
Very nicely worded. I especially liked the unrequited love one. Well done.
Greensleeves Hubs (author) from Essex, UK on August 02, 2011:
Thanks so much Ubanichijioke for your views. I've also noticed that the votes don't always seem to show, though I wonder if there's just a time delay in them appearing on the page? Anyway, although it's always really nice to receive the votes, the most important thing is that readers enjoy the articles, so I am just happy that you liked the page.
Alexander Thandi Ubani from Lagos on August 02, 2011:
I thank you for expressing these sentiments i would have loved to share. I am pleased and hope others will benefit too. Voted interesting
[i ve noticed that my vote sometimes do not reflect. Voted interesting hope it reflects]
Greensleeves Hubs (author) from Essex, UK on August 02, 2011:
Thankyou very much Derdriu for your nice comments. I'm glad you liked my sentiments.
Derdriu on August 02, 2011:
Greensleeves Hubs: All of the reflections were expressed well. I was not able to vote in the survey because I could not choose any one over the others, although the "mum" reflection was particularly poignant. I think that there are probably many who feel that they did not thank their parents or dear relatives for being there, especially in guiding through childhood.
Voted up + interesting + beautiful

domain: literature


text:
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domain: psychology


|Publication number||US5001631 A|
|Application number||US 07/255,190|
|Publication date||Mar 19, 1991|
|Filing date||Oct 7, 1988|
|Priority date||Oct 7, 1988|
|Also published as||CA1325065C, EP0362874A2, EP0362874A3|
|Publication number||07255190, 255190, US 5001631 A, US 5001631A, US-A-5001631, US5001631 A, US5001631A|
|Inventors||Patrick F. Castelaz|
|Original Assignee||Hughes Aircraft Company|
|Export Citation||BiBTeX, EndNote, RefMan|
|Patent Citations (11), Non-Patent Citations (2), Referenced by (8), Classifications (24), Legal Events (8)|
|External Links: USPTO, USPTO Assignment, Espacenet|
1. Technical Field
This invention relates to information processors, and more particularly, to an information processor having a number of interconnected processing cells with randomly triggered adaptive cell thresholds.
Of the many problems that information processors are used to solve, optimization problems of the general class of constrained assignment problems are among the most difficult. This is because constrained assignment problems often are not solvable with a single solution but there may be a range of solutions of which the "best" solution is sought. In general, assignment problems involve choosing a particular solution where there are more choices than there are possible solutions. Often one entity is to be selected from among many and assigned to one and only one other entity in such a way to force the entire assignment over all entities to be optimal in some sense. Where individual "costs" are assigned to each entity-to-entity mapping the problem becomes one of minimizing the total cost. Examples of assignment problems include optimal plot-to-track correlation processing, the traveling salesman problem, optimal weapons allocation, deghosting for angle-only (passive) targets detected by three or more sensors, computerized tomography, multi-beam acoustic and ultrasound tracking, nuclear particle tracking, etc.
Previous approaches to assignment problems have emphasized solutions in software on general purpose computers. One disadvantage with software solutions to assignment problems is that they require massive computational power and are exceedingly slow for application to real-time or near-real-time problems such as angle-only target location problems. This is because, these problems frequently involve a "combinatorial explosion", an exponential blowup in the number of possible answers. Thus, to solve the deghosting problem, conventional solutions, even using advanced state of the art array and parallel processors, have difficulty handling real-time problems of realistic sizes. For example, conventional solutions of the deghosting problem are sufficiently fast up to about 15 targets, but become exponentially computation-bound beyond that. For numbers of targets in the range of 30 or so, typical software approaches using integer programming techniques could require virtually years of VAX CPU time.
Others have suggested approaches for solving assignment problems utilizing neural networks. Such systems are called neural networks because of their similarity to biological networks in their structure and in their ability to exhibit self-learning. For example, see U.S. Pat. No. 4,660,166, issued to J. Hopfield, where a type of neural network is used to solve the Traveling Salesman Problem. Others have suggested the use of a neural network technique known as simulated annealing. See S. Kirkpatrick, Gelatt, and Vecchi: "Optimization by Simulated Annealing", 220 Science, p. 671-680 (1983). However, while algorithms using this approach have been developed, to the applicant's knowledge, actual working architectures have not been implemented. Also, neural nets such as the one described in U.S. Pat. No. 4,660,166 are generally not fast enough for real-time applications of reasonable complexity. Recent results suggest severe limitations to the size of problems addressable by Hopfield nets. For example, the traveling salesman problem fails for more than thirty cities.
Thus it would be desirable to provide an information processor that reduces the computation time required to solve constrained assignment problems of realistic sizes in real-time.
Pursuant to the present invention, an information processor is provided which can rapidly solve assignment problems, having a relatively simple architecture. The processor utilizes a matrix of simple processing elements, or cells, that are connected together in a regular structure. The cells accept as input, data which represents information, or "costs" in an assignment problem in two or greater dimensions. The interconnection structure between the cells is fixed to represent the position of the costs in the asociated constraint spaceof the assignment problem. A means for generating a randomly varying signal, such as a random number generator is provided for each cell. A variable threshold means is associated with each cell and is triggered by the random number generator. As a result, the cost can only be transmitted by the cell when the random signal exceeds the threshold. An accumulator, or summer, external to the cells is provided to add up all of the costs which represent a given tentative solution to the problem. This sum is then compared by a comparator to determine the goodness (nearness to the best solution) of the current solution. This may involve comparison with an absolute criteria, or other criteria, such as running history of solutions to date for the particular problem being processed.
Once the above comparison is made, an adjustment is made in the variable thresholds. In particular, if the sum of the cost for the current solution is classified as good, the thresholds for those cells are lowered, otherwise the thresholds are raised. In this way, the probability of getting an output from cells contributing to a good solution is increased. The resulting collective processing leads the activity of the processor toward a final stable state which corresponds to a near optimal solution of the assignment problem represented by the costs.
The various advantages of the present invention will become apparent to one skilled in the art by reading the following specification and by reference to the following drawings in which:
FIG. 1 is a diagram of the architecture of the cellular network assignment processor in accordance with the teachings of the present invention.
FIG. 2 is a diagram of a typical deghosting problem with angle-only data from three sensors.
Referring to FIG. 1, a diagram of the architecture of the cellular network assignment processor using randomly triggered adaptive cell thresholds in accordance with the present invention is shown. In the preferred embodiment the cellular network assignment processor 10 is adapted to solve constrained assignment problems such as deghosting for angle-only information from three sensors. The cellular network assignment processor 10 contains an array of processing cells which comprise cost registers 12, noise generator 14, and adaptive thresholds 16. The cost registers 12 receive and store information from a host CPU 18. The host CPU 18 can access each cost register 12 individually. This information corresponds to costs in an assignment problem of two or greater dimensions. For example, in deghosting angle-only information from thre sensors, there will be a three dimensional cube of cells. Rows of cells on a first, or x, axis in a first plane in the cube will correspond to all possible sensor angles for a first sensor. Locations on the y axis, perpendicular to the x axis, corresponds to all the possible sensor angles for a second sensor. Likewise, locations on the z axis, perpendicular to both the x and y axis represent all possible sensor angles for a third sensor. For simplicity, FIG. 1 shows the cells in two dimensions only.
Referring now to FIG. 2, the information to be stored in the cost registers 12, represents triple intersects of the three sensors. That is, when a sensor 20 detects a target 22, a line is plotted from the sensor location to the target. Every point where the lines from the three sensors all intersect is called a triple intersect. Note, however, that some of these intersects represent real targets 22, and are thus valid, while some are "accidental" triple intersects and are invalid, or "ghosts" 24. The assignment problem then is to eliminate the ghosts, or deghost the data, so that only actual targets are detected.
As will be appreciated, a host CPU 18 such as the one in FIG. 1 can detect the triple intersects and transmit the angular data from each sensor that corresponds to each triple intersect. In addition, the host CPU 18 will also calculate the area of the triangles 26 found at each triple intersect. This triangle 26 is formed because of measurement errors in the sensor data. Even for valid targets, the triple intersect will not be a point but will instead by a small triangular area formed by the three lines. The host CPU 18 will call a triple intersect those intersects having a triangle with an area below a given criteria. The host CPU 18 will then transmit digital data representing this area for each triple intersect to the cost register 12 associated with those three angles for the three sensors. It is the area of this error triangle that is the "cost" in the assignment problem. The processor 10 minimizes total cost by minimizing the area of the summed triangles. Since triangles corresponding to ghost will tend to be larger than those corresponding to real targets, the processor 10 eliminates ghosts by choosing solution having smaller triangles. The assumption that real targets will have smaller triangles than ghost is generally valid for problems having up to about 50 targets. As the density increases, with greater number of targets, the number of ghosts become extremely large. For example, there may be tens of thousand of ghosts. At this point, the probability is increased that some ghosts may have smaller triangles than targets and performance could begin to degrade.
In sum, the host CPU 18 receives the angular data from the sensors, determines where triple intersects occur and sends the area of the error triangle of the triple intersect to the cost register 12 associated with that set of angles from the three targets. The cost registers 12 then, by their location in the processor 10, represent a mapping of a set of three angles, and each cost register 12 stores the area of the error triangle for that particular triple intersect.
Each cost register 12 has associated with it a noise generator 14 and an adaptive threshold 16. The noise generator 14 may comprise a number of conventional means for generating a randomly varying signal. While the processor 10 is operating, all of the noise generators 14 are free running simultaneously. Each noise generator 14 is coupled to an associated adaptive threshold 16, which is also coupled to the cost register 12. The adaptive threshold 16 acts as a gate in combination with the noise generator 14 to permit the cost register 12 to transmit the cost value it contains only under certain circumstances. In particular, when the instantaneous magnitude of the signal generated by the noise generator 14 exceeds the threshold value in the adaptive threshold 16, the cost in the cost register 12 may be fed into a data line 28. Likewise, when the magnitude of the signal generated by the noise generator 14 is lower than the threshold value in the adaptive threshold 16, the cost value in the cost register 12 cannot be fed into the data line 28.
Once the cost registers 12 are stored with all of the costs corresponding to triple intersects, the task of the processor 10 is to select those cost registers 12 that represent real targets and eliminate those representing the ghosts. In the preferred embodiment, based on the information processed by the host 18, the processor 10 does not know which intersects represent real targets and which are ghosts. However, the processor 10 does know how many real targets there are. To determine real targets from ghosts, the processor 10 makes a series of tentative selections of proposed solutions having the correct number of choices and then decides whether this solution is a good or a bad solution. This decision is made by adding up all of the costs for a given solution. The lower the total cost, the better the solution. The thresholds 16 associated with costs for good solutions are then lowered, while the thresholds 16 associated with costs contributing to bad solutions are raised. After a number of such cycles, the processor 10 eventually moves in the direction of a valid optimal solution to the problem. It should be noted that the inverse of the area of the error triangles could be used for cost values. In such a case the processor would be instructed to maximize rathe than minimize total cost.
To begin solving a problem, the adaptive thresholds 16 are set to some initial value. These values may be identical or may vary among cells and the values chosen for the initial thresholds will depend on such factors as, for example, the corresponding individual cost values. Initial thresholds may be set proportional to costs. After an initial period, each noise generator 14 generates a value which may or may not exceed the present threshold value. For those thresholds 16 which are exceeded, the cost value in the associated costs register 12 will be transmitted along the data line 28 to an accumulator 30. In addition, the associated location address of the cell corresponding to the three angles for the three sensors will also be transmitted along with the data in that cost register 12. Further, all cells in the same row and column (for a 2-D processor, along all three axes for 3-D (deghosting) processor) are instantly and simultaneously "disabled" from contributing to the current tentative solution, for example, their noise generators are "shut off". This insures only one contribution from each row and column to satisfy the fundamental assignment problem constraint of assigning M and only M things to N things. For those cost registers 12 where the noise generator 14 does not exceed the threshold, no cost value will be transmitted. The cost values reaching the accumulator 30 will be counted by the accumulator until the number of cost values equals the number of targets. Then the accumulator 30 will add up the costs to arrive at a total cost for the solution.
The accumulator 30 also contains a means for storing the address of each cost register 12 from which it receives a cost value. It will be appreciated that the summing may be accomplished by the accumulator 30 by conventional circuits capable of producing an output that is the sum of the values it receives as input. The sum is then sent along a data line 32 to a comparator circuit 34. The comparator 34 compares the sum to a particular number, or criterion, to determine if the solution is a "good" or a "bad" solution. This criterion may be an absolute preselected criterion or it may simply be a running history of the best solutions-to-date for the particular problem being processed. In the latter case, the comparator 34 will also have a means for storing the sum from previous solutions and a means for comparing the current solution to the previous solution, and for storing the better or the two. It should be noted that the first tentative solution will be a result of the "randomly" selected cost registers 12 and since there is no history of solutions an absolute criteria must be used for this first solution. Consequently, the first solution is stored as "best" by default. Later solutions can then be compared to a running history.
It the solution is classified as good, the comparator 34 will transmit the associated location address of the costs contributing to the solution to a threshold adjustment circuit 36. The threshold adjustment circuit 36 will then transmit a signal to the adaptive thresholds 16 associated with those addresses contributing to the current solution. This signal will cause the adaptive thresholds 16 to lower for those cost register 12 contributing to good solutions. In this way, the probability of having those cost registers 12 contribute to future solutions is increased. Optionally, the adjustment circuit 36 may also raise the thresholds for all other cost registers 12. Since raising the thresholds for some cost registers 12 is relatively equivalent to lowering the thresholds of the others, the step of lowering the thresholds for noncontributing cost registers 12 is not an absolute necessity.
In other cases, the comparator 34 will determine that the current solution is bad. That is, the summation of the cost values for the current solution is less than the selected criterion. In such cases, the threshold adjustment circuit 36 will raise the thresholds in the adaptive thresholds 16 associated with the cost registers 12 contributing to that bad solution. In this way, the probability is decreased that those cost registers 12 contributing to the bad solution, will contribute to future solutions.
As mentioned above, the comparator circuit 34 also stores the address of the cost registers 12 which contribute to the best solution-to-date. An interrupt circuit 38 may be employed to stop the processor 10 at any time to retrieve the best solution-to-date stored in the comparator circuit 34. The interrupt circuit 38 is connected to the host computer 18 and also to the comparator 34. In this way, the best solution-to-date can be retrived at any time. This is often a requirement for real-time systems where the time the processor is given to arrive at a solution may vary. In cases where the interrupt is not used, a limit on the number of processing cycles may be set. This limit may be achieved by employing a counter in the comparator circuit 34 which counts the number of solutions or cycles produced and causes the processor 10 to stop and transmit the best solution-to-date after the predetermined number of cycles has been exceeded. The complexity of the problem to be solved will determine the number of cycles to achieve an optimal solution. It has been found that the processor 10 after a given number of cycles for a particular problem will reach a stable state and settled into a particular solution so that additional cycles will not achieve a better solution.
It should be noted that beyond solving the deghosting problem for angle only data from three sensors, the present invention may be adapted to solve other assignment problems such as the Traveling Salesman Problem, optimal plot-to-track correlation processing, optimal weapons allocation, computerized tonography and others. It will be appreciated that the basic components of the processor 10 may be implemented with conventional electrical circuits including programmable logic devices. Also, optical devices may be used for some of the functions.
From the foregoing description it can be appreciated that the present invention provides a processor 10 capable of solving assignment problems in real-time, at speeds of 3-4 orders-of-magnetide faster than conventional solutions. Those skilled in the art can appreciate that other advantages can be obtained from the use of this invention and that modifications can be made without departing from the true spirit of the invention after studying the specifications, drawings and following claims.
|Cited Patent||Filing date||Publication date||Applicant||Title|
|US3443078 *||Sep 16, 1966||May 6, 1969||Electronic Associates||Analogue computers for least-cost optimization|
|US3562502 *||Aug 14, 1967||Feb 9, 1971||Stanford Research Inst||Cellular threshold array for providing outputs representing a complex weighting function of inputs|
|US3950733 *||Jun 6, 1974||Apr 13, 1976||Nestor Associates||Information processing system|
|US4025919 *||Nov 14, 1975||May 24, 1977||Westinghouse Electric Corporation||Automatic target detector|
|US4254474 *||Aug 2, 1979||Mar 3, 1981||Nestor Associates||Information processing system using threshold passive modification|
|US4326259 *||Mar 27, 1980||Apr 20, 1982||Nestor Associates||Self organizing general pattern class separator and identifier|
|US4450530 *||Jul 27, 1981||May 22, 1984||New York University||Sensorimotor coordinator|
|US4591980 *||Feb 16, 1984||May 27, 1986||Xerox Corporation||Adaptive self-repairing processor array|
|US4802103 *||Jun 3, 1986||Jan 31, 1989||Synaptics, Inc.||Brain learning and recognition emulation circuitry and method of recognizing events|
|US4858147 *||Jun 15, 1987||Aug 15, 1989||Unisys Corporation||Special purpose neurocomputer system for solving optimization problems|
|US4914604 *||Oct 7, 1988||Apr 3, 1990||Hughes Aircraft Company||Processor for analyzing angle-only data|
|1||*||Lippman, Richard P. An Introduction to Computing with Neural Nets IEEE ASSP MAG. 4/87.|
|2||Lippman, Richard P.-"An Introduction to Computing with Neural Nets" IEEE ASSP MAG. 4/87.|
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US5050096 *||Sep 26, 1989||Sep 17, 1991||Northrop Corporation||Path cost computing neural network|
|US5072379 *||May 26, 1989||Dec 10, 1991||The United States Of America As Represented By The Adminstrator Of The National Aeronautics And Space Administration||Network of dedicated processors for finding lowest-cost map path|
|US5140670 *||Oct 5, 1989||Aug 18, 1992||Regents Of The University Of California||Cellular neural network|
|US5345539 *||Oct 30, 1991||Sep 6, 1994||The Secretary Of State For Defence In Her Britannic Majesty's Government Of The United Kingdom Of Great Britain And Northern Ireland||Radar apparatus using neural network for azimuth and elevation detection|
|US5390679 *||Jun 3, 1993||Feb 21, 1995||Eli Lilly And Company||Continuous cardiac output derived from the arterial pressure waveform using pattern recognition|
|US5454064 *||Nov 22, 1991||Sep 26, 1995||Hughes Aircraft Company||System for correlating object reports utilizing connectionist architecture|
|US5479572 *||Jun 17, 1992||Dec 26, 1995||Siemens Corporate Research, Inc.||Artificial neural network (ANN) classifier apparatus for selecting related computer routines and methods|
|US5797395 *||Dec 22, 1994||Aug 25, 1998||Eli Lilly And Company||Continuous cardiac output derived from arterial pressure waveform using pattern recognition|
|U.S. Classification||705/7.26, 706/19, 706/29, 705/7.25, 705/7.37|
|International Classification||G06Q10/06, G06Q10/04, G06N3/00, G06F15/80, G06F15/173, G06F15/16, G06F15/18, G06N3/04, G06N99/00|
|Cooperative Classification||G06Q10/06375, G06N3/04, G06Q10/06316, G06Q10/04, G06Q10/06315|
|European Classification||G06Q10/04, G06Q10/06375, G06Q10/06315, G06Q10/06316, G06N3/04|
|Oct 7, 1988||AS||Assignment|
Owner name: HUGHES AIRCRAFT COMPANY, LOS ANGELES, CA, A CORP.
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST.;ASSIGNOR:CASTELAZ, PATRICK F.;REEL/FRAME:004958/0282
Effective date: 19881007
Owner name: HUGHES AIRCRAFT COMPANY, A CORP. OF DE,CALIFORNIA
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:CASTELAZ, PATRICK F.;REEL/FRAME:004958/0282
Effective date: 19881007
|Oct 25, 1994||REMI||Maintenance fee reminder mailed|
|Mar 20, 1995||FPAY||Fee payment|
Year of fee payment: 4
|Mar 20, 1995||SULP||Surcharge for late payment|
|May 30, 1995||FP||Expired due to failure to pay maintenance fee|
Effective date: 19950322
|Apr 30, 1998||AS||Assignment|
Owner name: HUGHES ELECTRONICS CORPORATION, CALIFORNIA
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:HE HOLDINGS INC.;HUGHES ELECTRONICS, FORMERLY KNOWN AS HUGHES AIRCRAFT COMPANY;REEL/FRAME:009342/0796
Effective date: 19971217
|Sep 3, 1998||FPAY||Fee payment|
Year of fee payment: 8
|Sep 18, 2002||FPAY||Fee payment|
Year of fee payment: 12


Head-on collision in Somers claims life of elderly driver
A head-on collision in Somers claimed the life of an elderly woman and seriously injured three other people Saturday.
State police say the 80-year-old driver drove her Honda into oncoming traffic and crashed head on into a pick-up truck on Route 100. Somers firefighters used the Jaws of Life to try and save the driver of the Honda. Police say the woman died upon arrival at the Westchester Medical Center. All three people in the pick-up were seriously injured. Two were taken by helicopter to the hospital. All are expected to survive their injuries.
Accident investigators were on the scene to try and determine exactly how the collision happened and why the Honda veered into the oncoming truck.


text:
Genshin Impact Heart Charms
NEW CHARMS AVAILABLE FOR PRE ORDER! ALL NEW CHARMS WILL SHIP OUT EARLY MAY.
Friendship? Shipping? Family bonds? The possibilities are endless. Mix and Match your favorite characters to form a complete heart.
+ Clear Acrylic
+ Double sided
+ Comes with gold key ring
All charms are mailed in bubble mailers and come with a clear protective film. Please remove film upon receiving.
More characters coming soon

domain: artistic


text:
The second game of a Monday Night Football double-header will feature the San Francisco 49ers playing host to their NFC West rival Los Angeles Rams. Tonight will mark the first time since the 1994 season that the Rams will take the field for a regular season football game under the Los Angeles moniker.
Arizona and Seattle figure to be the strength of the NFC West yet again and both teams have Super Bowl aspirations. The Cardinals’ championship window with quarterback Carson Palmer may be closing, which is why the team traded for pass rusher Chandler Jones.
The calendar has turned to July, which means it’s almost time for the NFL to get back to business. The regular season doesn’t start until Sept. 8, but teams will open training camp later this month, officially starting the path for what eventually will lead to Super Bowl LI in NRG Stadium in Houston on Feb. 5, 2017.

domain: news


text:
Alan C. Legasto, M.D.
Specialties and Expertise
- Heart Imaging
- Thoracic Radiology
- Chest Imaging
- Noninvasive Cardiac Imaging
- Cardiac Magnetic Resonance Imaging
- Cardiac MRI
- MRI of the Heart
- MRI Chest
- Magnetic Resonance Angiography
- Cardiac CT
- CT Scan of the Heart
- Chest CT
- CT Scan of the Chest
- Chest X-Ray
- PET Scan
- Positron Emission Tomography
- Lung Disease
- Lung Cancer
- Screening For Lung Cancer
- CT Lung Screening
- Lung Cancer-Diagnostic Testing
- Low Dose Computed Tomography of Lungs For Lung Cancer Screening
- Heart Disease
- Congenital Heart Disease
- Valvular Heart Disease
- Pulmonary Arterial Hypertension
Alan C. Legasto, M.D. is a board-certified radiologist specializing in thoracic imaging. He is Assistant Professor of Radiology at Weill Cornell Medical College and Assistant Attending Radiologist at the NewYork-Presbyterian Hospital-Weill Cornell Campus.
Dr. Legasto earned his B.A., in English, from the State University of New York (SUNY) at Buffalo in 1996. He then received his M.D. degree from the Ross University School of Medicine in Dominica, West Indies in 2000.
Following his transitional internship year at St. Vincent’s Medical Center in Bridgeport, Connecticut, Dr. Legasto completed residency training in Diagnostic Radiology (2001-2005) at Long Island College Hospital in Brooklyn. This was followed by a one year fellowship in Thoracic Radiology at the Massachusetts General Hospital in Boston.
After training, Dr. Legasto joined the Departments of Radiology at Beth Israel Medical Center (NYC) and St. Lukes Roosevelt Hospital Center (the former Continuum Health Care System) in 2006 and was appointed Section Chief of Cardiothoracic Radiology in 2007. He was on the faculty the Albert Einstein College of Medicine of Yeshiva University as Assistant Professor of Radiology from 2006 through 2014. Dr. Legasto started on the Weill Cornell Medical College faculty as Assistant Professor of Radiology in March 2014.
Dr. Legasto achieved Board Certification in Diagnostic Radiology from the American Board of Radiology in 2005.
Dr. Legasto’s clinical expertise is in thoracic and cardiac imaging. He interprets a wide range of imaging examinations, including radiography, CT, MRI, PET, and ultrasound.
His research interests include MRI imaging of the chest. In addition to clinical activities, Dr. Legasto is an active teacher of residents, fellows, and medical students. At Beth Israel Medical Center, Dr. Legasto was voted, by the radiology residents, as the “Teacher of the Year” for three year out of the eight years he was at Beth Israel. In 2013 he was selected as “SuperDocs Rising,” a peer elected acknowledgement for the New York Times Magazine.
Dr. Legasto is a member of the following professional societies:
- Society of Thoracic Radiology
- American College of Radiology
- Radiological Society of North America (RSNA)
- American Board of Radiology
Clinical and Academic Positions
- Assistant Attending Radiologist - NewYork-Presbyterian Hospital
- Assistant Professor of Clinical Radiology - Weill Cornell Medical College, Cornell University
- Associate Attending Radiologist - NewYork-Presbyterian Hospital
Education and Training
- M.D., Ross University School of Medicine and Veterinary Medicine (Dominica, WI), 2000
- B.A., State University of New York at Buffalo, 1996
Insurance Plans Accepted
The following represents most of the managed care plans accepted by this doctor. If your insurance carrier does not appear here please contact the doctor’s office as they may have individual contracts not included on this site.
* indicates this doctor is no longer accepting new patients with this insurance plan.
- AETNA - HMO
- AETNA - Medicare
- AETNA - PPO
- Aetna Weill Cornell Employee Managed Care Plan
- Aetna Weill Cornell Employee PPO Plan
- Aetna-NYP - EPO/POS
- Affinity Access
- Affinity Health Plan
- AgeWell New York
- Amida Care
- Emblem Select Care
- Empire Blue Cross/Blue Shield - Blue Access
- Empire Blue Cross/Blue Shield - Blue Connection
- Empire Blue Cross/Blue Shield - EPO
- Empire Blue Cross/Blue Shield - HMO
- Empire Blue Cross/Blue Shield - Mediblue (Senior)
- Empire Blue Cross/Blue Shield - PPO
- Empire Blue Cross/Blue Shield HealthPlus
- Empire Blue Cross/Blue Shield HealthPlus - CHP
- Fidelis Care
- GHI - CBP
- Health First
- Health Insurance Plan of NY (HIP)
- Health Insurance Plan of NY (HIP) - Medicaid
- Health Insurance Plan of NY (HIP) - Medicare
- Oxford Health Plans - Medicare Advantage
- Oxford Health Plans - Metro/Core/Charter
- Oxford Health Plans - Liberty
- Oxford Health Plans - Freedom
- Rockefeller University - Trustmark
- United Empire
- United Healthcare
- United Healthcare - Community Plan
- United Healthcare - Medicare
- VNSNY CHOICE - HMO
- VNSNY CHOICE - Medicare
- WellCare of NY
- WorldWide Medical
Locations and Appointments
Relationships and collaborations with for-profit and not-for profit organizations are of vital importance to our faculty because these exchanges of scientific information foster innovation. As experts in their fields, WCM physicians and scientists are sought after by many organizations to consult and educate. WCM and its faculty make this information available to the public, thus creating a transparent environment.
No External Relationships Reported

domain: medical


Elvis Presley: Did the King of Rock and Roll Decorate Graceland For Christmas?
Elvis Presley‘s Graceland home in Memphis, Tennessee, is beautiful any time of year. However, it really comes alive during Christmastime. It was the King of Rock and Roll’s favorite holiday, and he spared no expense when decorating his home. However, did Elvis ever put up Graceland’s now-iconic Christmas decorations? His cousin Danny Smith weighs in.
Did Elvis Presley decorate Graceland for Christmas?
Christmas was the one time of year that Elvis Presley spared no expense to celebrate. He enjoyed giving gifts, the religious spirit of the holiday, and, of course, all the lights and sparkle that went with it.
In a video posted to his Memphis Mafia Kid YouTube channel, Elvis’ cousin Danny Smith discussed his love for the festive holiday season. He revealed if Elvis participated in decorating his beloved home for Christmas.
“The Memphis Mafia did not help with the decorations for Christmas,” Smith revealed. “That was done by Earl, Mike, and Albert, and if they had someone else working around part-time.”
He continued, “The electrical work was done mostly by George Coleman as far as the lights and stuff like that. No way in hell did Elvis help.”
“He didn’t supervise. When it was done, he seen it, but he wasn’t hands-on, let’s put it that way,” Smith concluded. “It just wasn’t Elvis.”
Elvis Presley adored Christmastime
According to a story published by Elvis.com.au, Elvis Presley stuck to a routine each Christmas Day. After most of the guests who visited Graceland on Christmas Eve went to bed or home, Elvis and members of the Memphis Mafia would place Lisa Marie Presley’s gifts under the tree.
On Christmas morning, Elvis would talk about his mother and the Christmases of his childhood. He would reflect on his gratitude for his success and wait for Lisa Marie to wake up, come from her bedroom upstairs, and find her Christmas gifts.
The driveways and the main house were lined with blue lights, and in front were six 8-foot Christmas trees decorated with multi-colored lights. Graceland was completely decorated for the season, including a Christmas tree in the dining room.
Are the same Christmas decorations used today as when Elvis Presley lived in Graceland?
According to the official Graceland site, Elvis Presley purchased Graceland in the spring of 1957. On December 12 of that same year, he purchased a Santa and sleigh yard decoration that read, “Merry Christmas to All, Elvis.”
Graceland still uses that same sign today. Elvis purchased it for $300 from the Bain Sign Company of Memphis, Tenneesee.
For Christmas, Elvis asked for beautiful red drapes to decorate Graceland. When he lived there, Elvis used a white nylon Christmas tree, which rotated on its stand, and played Christmas carols. It was decorated with red ornaments.
The blue lights that lined Graceland’s driveway were a joke within the home. Elvis’ father, Vernon Presley, quipped that pilots from a nearby airport would get confused and land at Graceland.
Elvis also asked the lawn to be decorated with Santa and his sleigh, a Nativity Scene, and aluminum Christmas trees. When the company that leased the Nativity scene and aluminum trees went out of business, Graceland purchased the displays to ensure the continuation of Elvis’ holiday tradition, the site revealed.
Graceland’s holiday decorations and light displays will be up until early January 2024. Fans can see Graceland light up each night live on the GracelandCam.


Banks join forces to collect blood for Red Cross
By Becky Barclay
Published in News on December 13, 2010 1:46 PM
Financial institutions in Wayne County are joining together this holiday season to give the "gift of life." The seventh annual Bank Challenge will collect blood for the Wayne County chapter of the American Red Cross Tuesday, Dec. 21, from 12:30...
Please log in to see full story.


text: This unique swinging game board allows play inside and outside of Hogwarts. Explore the interior of Hogwarts and the grounds as you try to collect elements and capture the beasts. Be the first to collect all the clues, and figure out what magical beast you have captured! Play as your favorite Harry Potter character. One of the most well known franchises in history. This game will make you feel like you are in the wonderful world of Harry Potter. Designed for 2-4 players ages 8 and up.

domain: game


text:
Split your payments with Direct Debit
Join over 8,000 Leicester Tigers season ticket holders who spread the cost via our FEE FREE & INTEREST FREE - Direct Debit scheme.
The scheme runs from January through to December, so the earlier in the year you decide to buy, the less your monthly payments are.
The following year the amount is split into 12 equal payments, so a season ticket can be bought for as little as £24 per month (based on season 2018/19 prices).
|Set up Direct Debit by||Monthly Equal Payments|
To find out more about our season tickets or if you have any questions please fill in the enquiry form below:

domain: economics


text:
Another novel by the author of ‘The Line of Beauty’, this book is really so well constructed and written, even though the story line tends to wander a little. However, this author is just such a damn good writer that one can forgive him that and merely delight in the delicious prose for it’s own sake – and it’s really only in the last couple of ‘sections’ that it feels as if he has rushed to complete it, as mentioned by other reviews I have read. Interestingly, the author apparently started writing short stories after the success of The Line of Beauty, but they coalesced into this novel; and that perhaps explains the ‘jumpiness’ – but I’m not complaining!
It’s actually very clever, as each ‘section’ covers only a few days at most; usually a social gathering like a party or a funeral is involved, and they take place years apart, from the early twentieth century through into the beginning of the twenty first. Yet the characters and the dialogue do pull it all together, and the common thread, Cecil, influences each and every part of the book. It’s very British, very beautifully written, and I’m giving it a 9/10.
Beginning before the outbreak of the First World War, George Sawle, the youngest son of a comfortable middle class Home Counties family, brings home his wealthy and aristocratic university friend, Cecil Valance, a handsome, confident budding poet, and it is Cecil and his family home that form the backbone of the book. (But really, it’s George’s sister Daphne who almost steals the show – especially as she’s the one who lives the longest and appears in the most scenes, from giddy girlhood, infatuated by Cecil, through her marriage to his brother, affairs, and general ups and downs of life to old age in a cottage with her long suffering son.)
Cecil is a Rupert Brookes type character, writing poetry and then dying in the trenches, and his legacy endures not only in his marble tomb at the family estate, but as a subject of a biography. The relationships of everyone else in the novel pivot around their relationships with him, even those who never met him, and it is a book that focuses on gay male relationships, which, given the time frame of the book, take us through the years of concealment to the open acceptance of same sex marriage in our time. Fundamentally, I feel this was the central theme, alongside the irreparable damage it is possible to inflict on children especially.
I really enjoyed reading this, although I took it quite slowly as I have been so busy getting BeckyandVince up and running again over here in Australia – reading has become a treasured escape from work once again. Not complaining though, the Mum’s Books Project is where the business started from, and I do love making my book thongs and sending them off around the world – Mum, I like to think, would have been quite proud what I’ve accomplished, although moving home to Australia stopped the wheels moving for some time.
So, book review number 100 to start 2022 – I’d love to gift this, Mum’s copy, forward if you’d like to read it so please get in touch either here or through the Instagram/Facebook pages, links below. And if you’d be kind enough to check out my new Australian Etsy shop and the delicious book thongs it contains, I’d be super grateful! I’m offering my lovely Mum’s Books Peeps a bit of a discount to celebrate reaching 100 on all the book thongs in store – use the code MUMSBOOKS01 at checkout for a tasty 10% off!
And – THANK YOU for being you, and being here!

domain: library


text:
It’s the perfect storm of fandom this year, as Batman is celebrating eighty years in pop culture, while “Batman Beyond” is celebrating its twenty year anniversary. For 2019, Warner finally unleashes their fantastic follow up “Batman Beyond” on Blu-Ray in a stellar Limited Edition box set that is also conveniently in time for Halloween and the impending holiday season. With the Limited Edition featuring an exclusive Batman Beyond Funko Pop, and the inevitably regular set coming down line, Warner will cash in for sure. “Batman Beyond” is still the juggernaut follow up to the classic Bruce Timm “Batman” series that hasn’t aged a bit, despite being conceived during a period where everything had to be futuristic, and darker.
In 2039, Gotham is a futuristic metropolis that is still corrupt, and crime ridden as ever. After troubled student Terry McGinnis is saved by an elderly Bruce Wayne, McGinnis stumbles upon Wayne’s secret as the Batman. When Terry’s father is murdered due to a botched deal with a business executive, Terry dons the weaponized Batman suit engineered by Bruce and seeks revenge. Forming an uneasy alliance, Bruce mentors Terry as the new Batman, and both seek to clean up Gotham of its crime wave once again. The writers know exactly how to deal in fan service, while also creating some dynamic new villains. Ironically most of the villains feel like distant children of Bruce Wayne’s enemies.
They include Inque, Spellbinder, Curaré and the enigmatic Society of Assassins. Timm and the team of writers build compelling and unique characters including Terry McGinnis (Will Friedle is iconic) who is a great successor to Bruce Wayne, as well as Ace the Bathound. Along with the return of Kevin Conroy as Bruce Wayne, there’s a top notch cast of performers including Stockard Channing, William H. Macy, Teri Garr and Michael McKean, John Ritter, Seth Green, Tim Curry, David Warner, Patton Oswalt, Ice-T, Johnny Galecki, and so many more. “Batman Beyond” is the right balance of sequel that pays homage to the original while also carving its own niche in the DC Animated Universe.
The new Limited Edition release comes packed in a box alongside a boxed Exclusive Chrome Funko Pop of Terry McGinnis’ Batman, as well as a small collection of Batman Beyond hologram pictures, and the Digital Copy for consumers. All fifty two episodes are included, with forty one fully restored on six whole discs. Featured is Nostalgic Tomorrow – A Batman Gathering, an All-New Featurette, including many of Batman Beyond’s core production team and actors gathering for a great roundtable discussion of the evolution and execution of the animated series. It includes Bruce Timm and Glenn Murakami, casting/dialogue director Andrea Romano, director James Tucker, writers Bob Goodman & Stan Berkowitz, and stars Kevin Conroy & Will Friedle. Knight Immortal is another All-New Featurette celebrating the excellent legacy of Dark Knight’s 80 years of crime fighting, as narrated by storytellers of the past, present, and future.
“Tomorrow Knight: The Batman Reborn” features storytellers exploring the rise of Terry McGinnis as Batman and Bruce Wayne’s relationship with the young hero as he mentors a new Dark Knight for modern times. There are a slew of entertaining and insightful audio commentaries by filmmakers and voice actors for four crucial episodes: “Rebirth, Part 1”; “Shriek”; “Splicers”; and “The Eggbaby.” There are also a slew of featurettes included, such as brief glimpses behind various episodes, “Music of the Knight,” a segment with producer Bruce Timm who introduces a key scenes from Batman Beyond, accompanied by the compelling score created for the series. There’s also “Inside Batman Beyond – Meet the Creators” with producers Alan Burnett, Bruce Timm, Glen Murakami and Paul Dini, all of whom discuss the creative process behind Batman Beyond and its first season.
Jason Hillhouse moderates. There’s also a trailer for Batman’s 80th Anniversary Collection. “Inside Batman Beyond: The Panel” is an in-depth discussion with producers Bruce Timm, Alan Burnett, Glen Murakami and Paul Dini, all of whom discuss season two of Batman Beyond in great length with moderator Jason Hillhouse. There’s the six part “Inside Batman Beyond: Season 3” including discussions with producers Bruce Timm, Alan Burnett, Glen Murakami and Paul Dini, directors Butch Lukic and James Tucker, and voice actor Will Friedle, all of whom discuss various moments like the Batman musical, the inclusion of the new Justice League, and the finale featuring Kobra. There’s also “Gotham: City of The Future,”a Close-Up Look at Gotham City Circa 2039, the modernization and the inspirations for its high-tech design and massive scale, and “The High-Tech Hero,” exploring the evolution of the new Bat Suit and its futuristic design and capabilities with Batman storytellers.
Finally there are two feature length films including “Batman Beyond: Return of the Joker” the hit 2000 film which features Batman and Bruce confronting Batman’s worst foe. It’s fully remastered and restored. As well, there’s “Secret Origin: The Story of DC Comics” the documentary about the creation and influence of DC Comics and its legacy.


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KANSAS CITY, Mo. - About 1,700 Kansas City families lined up at Della Lamb at 500 Woodland Ave Friday for Operation Santa Claus 2012. It's an annual holiday program that serves low-income families in Kansas City.
Families are supplied with holiday food, clothing and gift for the entire family.
Judy Akers, executive vice president of Della Lamb, spent much of Friday morning handing out bags of clothing.
"These are bags with children's clothing, so for each child in the family there will be one new sweat suit, one new pair of underwear, a pair of socks, a new hat, new pairs of gloves," she said. "We're serving over 2,200 children plus another 535 teenagers."
Akers said Della Lamb collects brand new clothing and household items throughout the year to prepare for the Santa Claus event.
"We have seen a tremendous increase in the number of families who are asking for help, many for the first time," she said.
Akers said that due to the generosity of the community, the organization can provide a complete Christmas for a family of four.


text:
The degeneration of axons is a core pathological feature in many neurological diseases including Parkinson's disease, Alzheimer's disease, amyotrophic lateral sclerosis, multiple sclerosis and spinal cord lesion. It often precedes the death of the neuronal cell body and results in impaired connectivity of the affected regions of the central nervous system (CNS) with high clinical relevance. The deficits are most often persistent due to the inability of CNS axons to regenerate, which is caused by inhibitory molecular cues of the glial environment in the adult CNS, the lack of neurotrophic responses and the low intrinsic regenerative ability of differentiated CNS neurons. Thus, therapeutic approaches to tackle neurodegenerative diseases should counteract axonal degeneration and foster regeneration of already lesioned axons in the inhibitory CNS environment. Interestingly, increasing evidence suggests that collapsin response mediator protein-2 (CRMP2) (also known as dihydropyrimidinase-related protein 2 (DPYSL2)) is a multifunctional molecule that mediates both axonal re- and degeneration and could thus be a very promising drug target in these diseases.
CRMP2 Promotes Neurite Outgrowth
CRMP2 is a cytoplasmic protein that is highly expressed in neurons and oligodendrocytes in the developing and adult CNS. It has been implicated in several neuronal processes, mainly neurite outgrowth, but also in axon/dendrite specification, neuronal polarity, kinesin-dependent axonal transport, microtubule dynamics, synaptic assembly, neurotransmitter release and calcium channel regulation (Hensley et al., 2011). Downstream molecular targets of CRMP2 comprise the cytoskeletal proteins tubulin, actin and vimentin, the motor protein kinesin, the calcium binding protein calmodulin and the N-type voltage-gated calcium channel CaV2.2. It has been shown that CRMP2 binds to α–β-tubulin dimers to promote microtubule polymerization and stabilization resulting in increased neurite outgrowth. Several upstream post-translational modifications regulate CRMP2 function, including glycosylation, oxidation, proteolysis and phosphorylation. Especially phosphorylation of CRMP2 has been studied extensively. Among the kinases that have been shown to phosphorylate CRMP2 at specific sites are glycogen synthase kinase (GSK)-3β, cell division protein kinase (Cdk)-5, Ca2+/calmodulin-dependent protein kinase (CaMK)-II, Rho-Kinase (ROCK), and the Src family kinase Fyn. The majority of these phosphorylations inhibit CRMP2 function resulting in neurite retraction, growth cone collapse and failure of regeneration when these kinases are over-activated after axonal injury, whereas basic physiological levels of CRMP2 phosphorylation, e.g., by GSK-3β or CDK-5, do not affect neurite outgrowth. Therefore, dephosphorylation or inhibition of excessive CRMP2 phosphorylation fosters axonal regeneration, enhances sensitivity to the neurotropic factor BDNF, and counteracts the inhibitory effect on axonal regeneration induced by chondroitin sulfate proteoglycan (CSPG) and myelin-associated glycoprotein (MAG) in vitro (Mimura et al., 2006; Nagai et al., 2016). After spinal cord injury in mice in vivo, inhibition of CRMP2 phosphorylation improved the recovery of motor and sensory functions and inhibited scaring (Nagai et al., 2016).
CRMP2 Affects Axonal Degeneration
Beside this compelling evidence that CRMP2 is crucial for axonal regeneration, several studies have demonstrated a major role of CRMP2 in axonal degeneration including neurodegenerative conditions like Alzheimer's disease and amyotrophic lateral sclerosis (Hensley et al., 2011). However, the underlying molecular mechanisms are still not understood in detail. In mouse dorsal root ganglia neurons in vitro, increased levels of the phosphorylated form p-CRMP2-T514 induced by activated GSK-3β were detected in neurites 6 hours after the initiation of Wallerian degeneration, while overexpression of non-phosphorylated CRMP2 significantly delayed Wallerian degeneration (Wakatsuki et al., 2011). Similarly, levels of the phosphorylated form p-CRMP-2-Thr555 that is induced by ROCK, were increased in degenerating axons in a mouse model of multiple sclerosis in vivo, while lower levels of p-CRMP-2-Thr555 were associated with more limited signs of axonal degeneration (Petratos et al., 2012). In mouse superior cervical ganglia cells after NGF deprivation in vitro, increased levels of the cleaved form of CRMP2 were observed in swellings of degenerating neurites (Touma et al., 2007), whereas overexpression of CRMP2 reduced the number of varicosities in neurites of cortical neurons after glutamate excitotoxicity (Hou et al., 2009). These results suggest a protective role of the physiological, non-phosphorylated CRMP2-isoform and a detrimental role of the phosphorylated and the cleaved form of CRMP2 in axonal degeneration. However, further studies are urgently needed to decipher the exact functions of different isoforms and phosphorylation states of CRMP2 and the involved molecular downstream targets in axonal degeneration.
Acute Axonal Degeneration in the Optic Nerve
We have previously analyzed the molecular mechanisms of acute axonal degeneration (AAD) in the optic nerve crush (ONC) lesion model in rat. AAD is the earliest form of axonal degeneration and is characterized by a rapid fragmentation of the adjacent proximal and distal axonal stump on both sides of the lesion within several hours after a focal axonal lesion. It is followed by Wallerian degeneration (WD) starting at 24–72 hours after lesion, which results in the complete fragmentation of the distal part of the axon. In the rat optic nerve in vivo, we previously demonstrated that a crush lesion leads to a strong transient calcium influx into the axon resulting in activation of autophagy, cytoskeletal abnormalities, dysmorphic mitochondria, bulb formation and finally axonal disintegration. The molecular mechanisms connecting these pathological features, however, remain unknown. Therefore we used the established rat ONC to further elucidate the molecular cascade of acute axonal degeneration (Zhang et al., 2016). Optic nerve injury is an excellent model system to study axonal degeneration, as it affects a well-defined axonal tract of the CNS that is surgically easily accessible. Moreover, axonal degeneration of the optic nerve is a critical event in several clinically relevant human disorders, including optic neuritis, glaucoma and hereditary optic atrophy.
Calpain is Activated Early in Acute Axonal Degeneration
Based on data from other studies, e.g., in the spinal cord, we first checked whether the calcium-dependent protease calpain was activated after ONC following calcium influx. Calpain activation was evaluated by analyzing the expression levels of the 145 kDa breakdown product (BDP) of spectrin (α-fodrin), which is a specific cleavage product of calpain. The levels of cleaved spectrin started to increase already at 5 minutes after ONC, and continued to rise up to 6 hours, while the levels of intact spectrin stayed stable, probably due to a rapid reproduction of the protein. Calpain activation was further demonstrated directly by analysis of both its pro-enzymatic and active isoform (76 kDa). The levels of the active isoform of calpain were increased in relation to its pro-enzymatic isoform at 6 hours after ONC, while the total protein levels of calpain were not changed. Interestingly, calpain activity increased slower on the distal side than on the proximal side of the crush site, which might relate to the subsequently distinct morphological fates of the proximal and distal stumps. Immunofluorescence analysis of the 145 kDa spectrin BDP revealed that calpain activation was specifically localized in the axons in the region morphologically affected by AAD. This local confinement of calpain activation further supports its importance in mediating AAD. Finally, the role of calpain inhibition on AAD was evaluated by in vivo live imaging, which allows the visualization of axonal changes in the anesthetized living rat. We found that pharmacological calpain inhibition with intravitreally injected calpeptin stabilizes the axons on the proximal side up to 6 hours after lesion while its protective effect was less pronounced on the distal side. These results establish calpain as the central molecular mediator of AAD downstream of calcium after ONC.
Cleavage of CRMP2 by Calpain Mediates Axonal Degeneration
In order to discover further molecular targets downstream of calpain, we checked expression levels of several previously described or predicted target proteins of the protease calpain after ONC with or without calpain inhibition with calpeptin. The protein that was regulated most was CRMP2. It has been shown before that calpain cleaves CRMP2 after traumatic brain injury (Zhang et al., 2007). We found that there was a significant increase in cleaved CRMP2 during AAD and that the cleavage of CRMP2 after ONC was suppressed by calpain inhibition in vivo, which was further confirmed at 6 hours after scratch of cortical neurons in vitro. Thus, the cleavage of CRMP2 in AAD is mediated by calpain activation. Although our data clearly indicate that enhanced calpain-activation and subsequent CRMP2-cleavage is located primarily in the axonal compartment of the optic nerve during AAD, it is possible that similar molecular mechanisms also occur in the surrounding glial cells (including oligodendrocytes and astrocytes) and might contribute to axonal degeneration at later time points. This should be analyzed in greater detail in the future.
Considering that CRMP2 cleavage was suppressed by calpain inhibition correlating with axonal degeneration, we thus evaluated the role of intact CRMP2 in AAD using adeno-associated viral vectors (AAV) overexpressing CRMP2. In vitro, we modeled AAD using a microfluidic chamber system, which allowed the specific analysis of the axonal compartment. We found that CRMP2 overexpression delayed the formation of axonal bulbs after axotomy of cortical neurons in vitro. This effect of CRMP2 on bulb formation was sustained over 8 hours after axotomy although some bulbs still developed over time. This finding suggests a crucial role of CRMP2 for the early formation of axonal bulbs during AAD. After ONC in vivo, CRMP2 overexpression almost completely prevented axonal fragmentation on the proximal side up to 6 hours after the lesion while the effect on AAD was less pronounced on the distal side. The magnitude of its axon-stabilizing effect on the proximal side of the lesion was similar to the one achieved by calpain inhibition, suggesting that CRMP2 is a major target of calpain in mediating AAD.
We observed no changes in the levels of cleaved CRMP2 despite overexpression of intact CRMP2, indicating that axonal degeneration is not mediated by a toxic mechanism of the cleaved CRMP2 fragment but rather by a loss of functional CRMP2 that is physiologically stabilizing axonal integrity. However, further experiments need to verify this hypothesis.
Interestingly, both calpain inhibition and CRMP2 overexpression exerted much stronger anti-degenerative effects on the proximal than on the distal side of the injury. Similar results were obtained earlier with ROCK2 downregulation. This suggests that axonal degeneration on the distal side is sustained more strongly and is harder to be counteracted at least by these interventions. While axonal transport and energy supply are most probably less severely affected on the proximal side, another possible reason for these findings is the rapid decrease of the axon protective factor nicotinamide mononucleotide adenylyltransferase (NMNAT) in the distal axon that was shown before to occur within 2–3 hours after axonal transection. Decreased levels of NMNAT are one of the major factors driving Wallerian degeneration and seem not to be affected by CRMP2 overexpression or calpain inhibition. However, this needs to be analyzed in more detail in the future.
CRMP2 Controls Bulb Formation and Axonal Transport during Axonal Degeneration
We next assessed the mechanisms underlying AAD downstream of CRMP2. Using live imaging of axonal mitochondria transport in cortical neurons in microfluidic chambers, we found that the percentage of motile mitochondria in axons was significantly decreased within 30 minutes after axotomy, returning to normal levels at later time points. These observations visualize an early transient impairment of axonal mitochondria transport in AAD that might be crucial for the development of axonal degeneration bulbs, which contain accumulations of mitochondria, and subsequent axonal fragmentation. CRMP2 overexpression, on the other hand, inhibited the observed impairment of axonal mitochondrial transport at 30 minutes after axotomy. Interestingly, the most pronounced effect of CRMP2 overexpression on bulb formation also occurs at 30 minutes after axotomy, coinciding with the peak of axonal transport impairment. It has been shown that CRMP2 interacts with the motor proteins kinesin and dynein, which drive antero- and retrograde axonal transport, respectively (Kimura et al., 2005; Arimura et al., 2009). It is thus very likely that the cleavage of CRMP2 affects its binding to these motor proteins, thereby resulting in the impairment of axonal transport.
Proteomics Analysis of the CRMP2 Interactome in Acute Axonal Degeneration
Next, we performed proteomics of optic nerve lysates and compared the proteome 6 hours after ONC to the unlesioned nerve. We found an early regulation of several proteins that are known to interact with CRMP2. Among other proteins, levels of the kinesin-like protein KIF1 were decreased at 6 hours after ONC. It has been shown that CRMP2 binds to KIF1 to regulate tubulin trafficking, the decreased levels of KIF1 may thus exacerbate the negative impact on axonal transport by cleavage of CRMP2. On the other hand, expression levels of several cytoskeletal proteins including spectrin and actinin as well as the mitochondrial protein MDH2 were increased, possibly reflecting the accumulation of cytoskeletal proteins and mitochondria due to impairment of axonal transport. We also found a down-regulation of PEA-15 which plays a role in the ERK/MAPK signaling pathway regulating neuronal cell survival, as well as GOT1, NIT2 and GNB1 which are involved in glutamate metabolism and signal transduction. Thus, the role of CRMP2 on AAD might be also mediated by interacting with these binding partners. Out of all these CRMP2 interactors, KIF1 might be the most interesting one, which should be followed up in the future.
In conclusion, our study further elucidates the molecular cascade underlying AAD assigning a central role to CRMP2 (Figure 1). After the initial transient calcium influx caused by the lesion, the protease calpain is rapidly activated in close proximity to the lesion site. Its localization defines the area of AAD. Calpain then cleaves CRMP2 leading to an impairment of axonal transportand formation of degeneration bulbs. Overexpression of CRMP2 attenuated axonal degeneration of the proximal axon.
Together with the well-established positive effects on regeneration our findings on its central role in axonal degeneration further support the favorable characteristics of CRMP2 as a promising drug target in neurodegenerative and neurotraumatic diseases that can positively mediate both axonal de- and regeneration.
Additional file:Open peer review reports 1 and 2.
Open peer review report 1 on “Collapsin response mediator protein-2 plays a major protective role in acute axonal degeneration”.
Arimura N, Hattori A, Kimura T, Nakamuta S, Funahashi Y, Hirotsune S, Furuta K, Urano T, Toyoshima YY, Kaibuchi K. CRMP-2 directly binds to cytoplasmic dynein and interferes with its activity J Neurochem. 2009;111:380–390
Gögel S, Lange S, Leung KY, Greene ND, Ferretti P. Post-translational regulation of CRMP in developing and regenerating chick spinal cord Dev Neurobiol. 2010;70:456–471
Hensley K, Venkova K, Christov A, Gunning W, Park J. Collapsin response mediator protein-2
: An emerging pathologic feature and therapeutic target for neurodisease indications Mol Neurobiol. 2011;43:180–191
Hou ST, Jiang SX, Aylsworth A, Ferguson G, Slinn J, Hu H, Leung T, Kappler J, Kaibuchi K. CaMKII phosphorylates collapsin response mediator protein 2 and modulates axonal damage during glutamate excitotoxicity J Neurochem. 2009;111:870–881
Kimura T, Arimura N, Fukata Y, Watanabe H, Iwamatsu A, Kaibuchi K. Tubulin and CRMP-2 complex is transported via Kinesin-1 J Neurochem. 2005;93:1371–1382
Mimura F, Yamagishi S, Arimura N, Fujitani M, Kubo T, Kaibuchi K, Yamashita T. Myelin-associated glycoprotein inhibits microtubule assembly by a Rho-kinase-dependent mechanism J Biol Chem. 2006;281:15970–15979
Nagai J, Owada K, Kitamura Y, Goshima Y, Ohshima T. Inhibition of CRMP2
phosphorylation repairs CNS by regulating neurotrophic and inhibitory responses Exp Neurol. 2016;277:283–295
Petratos S, Ozturk E, Azari MF, Kenny R, Young Lee J, Magee KA, Harvey AR, McDonald C, Taghian K, Moussa L, Mun Aui P, Siatskas C, Litwak S, Fehlings MG, Strittmatter SM, Bernard CC. Limiting multiple sclerosis related axonopathy by blocking Nogo receptor and CRMP-2 phosphorylation Brain. 2012;135:1794–1818
Touma E, Kato S, Fukui K, Koike T. Calpain
-mediated cleavage of collapsin response mediator protein (CRMP)-2 during neurite degeneration in mice Eur J Neurosci. 2007;26:3368–3381
Wakatsuki S, Saitoh F, Araki T. ZNRF1 promotes Wallerian degeneration by degrading AKT to induce GSK3B-dependent CRMP2
phosphorylation Nat Cell Biol. 2011;13:1415–1423
Zhang JN, Michel U, Lenz C, Friedel CC, Köster S, d’Hedouville Z, Tönges L, Urlaub H, Bähr M, Lingor P, Koch JC. Calpain
-mediated cleavage of collapsin response mediator protein-2
drives acute axonal degeneration
Sci Rep. 2016;6:37050
Zhang Z, Ottens AK, Sadasivan S, Kobeissy FH, Fang T, Hayes RL, Wang KKW. Calpain
-mediated collapsin response mediator protein-1, -2, and -4 proteolysis after neurotoxic and traumatic brain injury J Neurotrauma. 2007;24:460–472
Conflicts of interest:None declared.
Open peer reviewers:Steven Petratos, Brent Neumann.


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Love Christmas! Love Parties! Why not ask our entertainer to come and keep all the children entertained at your Christmas party so you can have a drink, chat to your friends and know your kids are having a great time too, cheaper than everyone getting a babysitter.
A totally Christmassy party with plenty of traditional games to keep everyone entertained from pass the Christmas pudding, reindeer antlers, pin the hat on Santa, build a snowman, Dear Santa, Christmas scavenger hunt and fishing for candy canes, its a totally awesome Christmas adventure with lots of prizes to be won. Plus there is our wonderful parachute with more games, popcorn and bubbles to pop, pop, pop!
You can even have an arts and crafts activity where everyone can decorate 1 decoration for their tree at home from Santa, a Snowman or a Reindeer. We bring all the materials to decorate from glitter, pens, jewels, stickers, feathers, etc.
This Party is for age 3+
Each child receives a small Christmas party bag (including up to 20 children, additional children will add a small charge to your package).


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Morganite rondelle & gold filled chain necklace
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Long sterling silver necklace with carved agate Shou bead and bronze metal clay pendant.
Ruby & gold filled ‘Y’ style asymmetrical chain necklace
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Multi beryl & aquamarine gold filled chain necklace
Chrysoprase faceted coin & gold filled chain necklace
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Carnelian Long Chain Necklace
Abalone coin & gold filled chain necklace
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GMK are pleased to announce that in 2019 the Beretta World will once again be held in the beautiful grounds of the Holywell Estate, Hampshire. The event will be held from Friday 28th June - Sunday 30th June 2019. This highly acclaimed event has been running for almost 30 years now and regularly attracts over 1,000 entries.
The 2019 competition will consist of 120 targets shot over 15 stands. As with the last couple of years, squads will either start on stand 1 or stand 9, finishing at stand 15 or 8 respectively.
Once again there will be a huge array of prizes from our generous sponsors, more details of which will be published closer to the event.


The Network of Resources (NoR) call is linked to the Open Science Earth Observation (OSEO) initiative and offers to research, development or pre commercial users which are of scientific or value adding nature the opportunity to exploit EO data collocated in a cloud environment using Resource Tier and Platform Tier Services.
The call is open to users from ESA Member States participating to the Earth Observation Envelope Program (EOEP-5).
The evaluation of eligible user requests is performed by ESA, with the subsequent sponsoring provided by ESA and the following external entities: CloudSIGMA, CREODIAS. SOBLOO.
The Open Science Earth Observation (OSEO) call offers to scientists the opportunity to exploit at no cost a full archive of EO data for science, applications and technological innovation, by offering Third Party services which exploit state of the art ICT.
The call is permanently open in priority to scientists from ESA, European Union member states and Africa until the ESA allocated resources are exhausted.
Please note that proposals already submitted/confirmed for the other calls released in 2007 and 2014 remain valid and do not need to be resubmitted.Funding of the activities solicited through this AO shall be covered by national/institutional resources. As a CAL/VAL PI or co-PI, access to Aeolus product quality information will become available to you first-hand and before the official product release. Furthermore, you will be given the opportunity to quickly learn cooperate directly with other Aeolus CAL/VAL PIs and to perform joint activities.
Within the framework of its Copernicus missions, ESA is pleased to announce the Sentinel-5 Precursor Calibration and Validation Team Call (S5PVT) that aims to engage leading expertise for the Calibration and Validation of the Sentinel-5 Precursor (S5P) in the mission validation team, providing independent experimental data, analysis and recommendations to critically assess the end-to-end performance of the instrument and its products. The main payload of S5P is TROPOMI (TROPOspheric Monitoring Instrument), a push broom imaging spectrometer realized by ESA in collaboration with the Netherlands Space Office (NSO). S5P is expected to provide information on atmospheric variables in support of European policies and Copernicus services. The S5p satellite was launched on 13 October 2017 and will provide over 7 years data to the user community.
ESA is offering all scientists with the possibility to perform bulk processing and/or validation of their own algorithms exploiting the large ESA earth-observation archive together with ESA available GRID computing and
dynamic storage resources.


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In the Victoria Theatre Green Room Bar
If you go down to the woods today you’re in for a big surprise!
Comedy duo Jed and Gary are going to tell you a story, well that is until a very naughty bear storms the stage!
Mayhem and madness ensue in this not-so-traditional telling of the Teddy Bear’s Picnic. There’ll be music, dancing, and pie facing madness…well what else would you expect from these festival favourites?!
Full of mischief, audience participation and lots of fun to keep the whole family laughing and entertained.
Don't forget to bring your teddy bear!
An adult only version of the show will be taking place at 8pm!
* Ticket prices include a Theatre Support Fee when booking via our Box Office and online. No other charges are applied.

domain: entertainment


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Read entire article: manilatoday.net/revolutionary-president-andres-bonifacio/
And with Bonifacio at the helm of the Philippines, would the country have been very different?
“I believe so. With Bonifacio in power, the Pact of Biak na Bato wouldn’t have happened. He would never have been fooled by the Americans. He would have led the Filipino people to continue the Revolution and we would have been a sovereign Philippines. Aguinaldo and his men should have cooperated with Bonifacio and the Katipunan, but Aguinaldo et al were full of pride with their elite educated leaders. Bonifacio had a one track mind when it came to the country’s freedom, just like Apolinario Mabini and Antonio Luna – definitely no compromise with the Americans.”
In the end, while there may be small hope that the current administration will act on the calls of this campaign for the Supremo, Chua is confident that as time goes on, more and more Filipinos will come to know the continuing relevance of Bonifacio and what he and the Katipunan fought and lived for.
“To recognize Andres Bonifacio’s presidency is to recognize a form of government that is not just a copy of the Western Style democracy but a concept that came from us—to uphold puri (honor) at kabanalan (spirituality) to have real kaginhawaan that leads to true kalayaan. A much needed attitude that each of us, especially our leaders must take into heart, before we can truly walk on the road to genuine freedom and progress. And more importantly, to recognize Andres Bonifacio’s presidency is to give justice to the man who built the Filipino nation,” he said.


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2013 Cascina Val del Prete Roero Vigna di Lino (750ml)15 4 0 0
Val del Prete translates to ‘valley of the priest’, referring to the Bishop of Asti who moved here in 1850 having been exiled. The estate was bought in 1977 by Bartolomeo Roagna who was from Priocca d’Alba, and his wife Carolina. They had worked the estate previously as sharecroppers, adding vines to existing crops like grains and fruit orchards. It is now run by their son Mario. Today, Mario Roagna is regarded as one of Roero’s rising stars. The winery is situated in the vineyards with a beautiful view of an amphitheater from the cellar. His philosophy is to plant only indigenous grape varieties such as arneis, barbera and nebbiolo and to let the characteristics of the terroir speak through the wine. Farming is done bio-dynamically and the past years have been spent converting to organic farming. Fermentation in the cellars is spontaneous with indigenous yeasts.
Roero is a small DOCG wine district in the hills of Piedmont, in north-western Italy. It is known particularly for its refreshing white wines made from Arneis, but also for its bold, fragrant reds made from Piedmont's signature red-wine grape, Nebbiolo. Roero DOCG red wine must be 100% Nebbiolo grown and produced within the delimited area of Roero. Roero must be aged in cellars for a minimum of twenty months, with a minimum of six months in wooden barrels. Roero Riserva must be aged at least 32 months total, with the same minimum of six months spent in wood.
"The estate's 2013 Roero Vigna di Lino is powerful, dense and explosive. Lavender, violet, spice and bluish-hued fruits give the 2013 much of its distinctive personality. Deceptive in its mid-weight structure, the 2013 offers quite a bit of depth. With time in the glass, the wine gains freshness and slightly redder tonalities in its fruit. This is a terrific expression of Roero Nebbiolo. Drinking window: 2018 - 2028" 92 points - Antonio Galloni (Vinous, August 2016)

domain: geography


A timing-based side channel exists in the OpenSSL versions 1.0.2-beta1 through 1.0.2u, 1.1.1-pre1 through 1.1.1s, and 3.0.0-alpha1 through 3.0.7. RSA Decryption implementation which could be sufficient to recover plaintext across a network in a Bleichenbacher-style attack. To achieve a successful decryption an attacker would have to be able to send a very large number of trial messages for decryption. The vulnerability affects all RSA padding modes: PKCS#1 v1.5, RSA-OEAP, and RSASVE. For example, in a TLS connection, RSA is commonly used by a client to send an encrypted pre-master secret to the server. An attacker that had observed a genuine connection between a client and a server could use this flaw to send trial messages to the server and record the time taken to process them. After a sufficiently large number of messages, the attacker could recover the pre-master secret used for the original connection and thus be able to decrypt the application data sent over that connection.
CWE-203 - Observable Discrepancy
The product behaves differently or sends different responses under different circumstances in a way that is observable to an unauthorized actor, which exposes security-relevant information about the state of the product, such as whether a particular operation was successful or not.


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A look at the MySpace and Facebook profiles of the '08 presidential candidates
FACEBOOK AVATAR: But like this photo from his Facebook profile, Edwards MySpace page is a
whole lot of beige.
With the first few presidential primary debates out of the way, we can stop pretending that our vote hinges on the candidates’ positions on Iraq, the economy or healthcare reform and start judging them on a subject more intrinsically related to their potential performance in the Oval Office ― their MySpace and Facebook profiles. The candidates are striving to do something new in hopes of swaying young voters to their platform. And fittingly, their new favorite channel is being provided courtesy of MySpace and MTV.
MySpace and MTV are combining powers to host a series of town-hall style dialogues with the 2008 crop of presidential wannabes on college campuses across the country. Candidates will answer questions submitted in real time by viewers through MySpaceIM, text messages, and emails. The first dialogue is slotted for today, September 27, in New Hampshire with Democratic candidate John Edwards.
But long before these debates were scheduled, the candidates were getting busy on the social networking. But how useful are these sites to voters? We’ve all heard friends complain about the irrationality of judging someone’s character from a one-dimensional representation rather than taking the time to gauge their personality face-to-face and then making an informed decision on the value of their friendship. Or some such nonsense. For the rest of us, Facebook and MySpace represent the easiest and most efficient method of assessing compatibility for a friend, a potential hook-up, or a presidential candidate. So before MTV and MySpace air the upcoming dialogues on MTV and MTVu and webcast them on MySpaceTV and MTV.com, let’s take a few minutes to examine the profiles of the ’08 contenders. Informative? Maybe. Entertaining? Definitely.
We’ll begin in the red corner with former Massachusetts Governor Willard Mitt Romney. Romney notably eschews the “Religious Views” box on his Facebook profile, though he does answer “Mormon” on his MySpace profile. Romney’s activities include “waterskiing” and “horseback riding with my wife” and his interests are “fixing our failing schools” and “winning the war against the jihadists.” Other highlights include a list of his favorite country music performers, an inspiring quote by his father, George Romney, and a four paragraph-long “About Me” section logging nearly every accomplishment in Romney’s business and political career. Following in his family-man campaign theme, his top featured friends on MySpace are his wife, Ann, and his five sons.
Former New York City Mayor Rudy Giuliani set his privacy settings on MySpace to “timid preteen.” Giuliani’s profile is only visible to people who he accepts as friends on MySpace. I could be wrong but I’m guessing that this isn’t the best technique for recruiting new members to his online campaign, especially while campaigning as strong and accessible. Giuliani declined to make a Facebook profile. Apparently he decided a one-dimensional representation wasn’t better than nothing at all.
: Lifestyle Features
, Barack Obama, Elections and Voting, Jack Bauer, More