text:
Frisco, TX — Policing for profit in the United States is now the new norm.
It has gotten so bad that the Canadian government has issued a public service announcement for its citizens warning them that American Road Pirates, aka police officers, may very well rob them upon entry into the US.
In the US, “298 departments and 210 task forces have seized the equivalent of 20 percent or more of their annual budgets since 2008” according to a report by the Post.
According to the US Department of Justice, the value of asset forfeiture recoveries by US authorities from 1989-2010 was $12,667,612,066, increasing on average 19.5% per year.
In 2008, law enforcement took over $1.5 billion from the American public. While this number seems incredibly large, just a few years later, in 2014, that number tripled to nearly $4.5 billion.
When we examine these numbers, and their nearly exponential growth curve, it appears that police in America are getting really good at separating the citizen from their property — not just really good, criminally good.
To put this number into perspective, according to the FBI, victims of burglary offenses suffered an estimated $3.9 billion in property losses in 2014.
That means that law enforcement in America has stolen $600,000,000 more from Americans than actual criminal burglars.
Some might try and say that this money and property is obviously “taken from criminals” in order to rationalize this theft on a massive scale. However, the government does not have to charge you with a crime, let alone convict you, to take your property and after they steal your property the burden of proof is on you to get it back.
In Philadelphia alone, more than $64 million in seized property has been taken in the last decade and 100% of it has gone into the pockets of cops, judges, and other bureaucrats with a hand in the treasure chest.
Consequently, none of the above cases include revenue generated from arbitrary traffic ‘laws’ for victimless crimes. The total number of people who receive speeding tickets only, is 41,000,000 a year with an average cost of $152.00 each. That is 1 in every 5 licensed drivers in the US.
The total number of speeding tickets paid each year $6,232,000,000 which breaks down to around $300,000 generated per police officer for speeding alone. Tack on seat belt violations, license plate lights, window tint, rolling stop signs, and expired state-mandated stickers and that number skyrockets.
Police departments need you to break traffic laws. Revenue generated from traffic tickets is not for your safety, it is necessary for the survival of police departments.
Brett Sanders, a local activist in Frisco, Texas is well aware of the state’s extortion racket. So, he devised an epic plan to make that racket known to the people who carry it out.
Earlier this year Sanders was given a ticket, otherwise known as a threat of police violence for failure to be extorted — he was travelling 39 mph in a 30 mph zone.
“I took it to a jury trial and argued for jury nullification,” Sanders told the Free Thought Project. However, according to Sanders, the “jury didn’t buy it.”
It is particularly rare to receive a ticket for less than 10 miles over and even more rare to have it stick when you go to court. However, as Sanders tells us, the judge and prosecutor are well aware of his activism in the area.
In January, Sanders and other activists signed up to be “crisis actors” in a government drill to infiltrate the drill and report on it from the inside.
In December, Sanders and the folks over at the aptly named organization Don’t Comply, took to the streets just outside the Austin Street Shelter in Dallas to perform, what has now become a revolutionary act – feeding the homeless.
The group was threatened with being shut down, as recent bits of legislation have made feeding the homeless near impossible without breaking a law. So, the group donned their AR-15 rifles and open carried the entire time — feeding hundreds of homeless people duiring the Christmas season.
The police officer who cited Sanders even admitted to treating Sanders harsh.
“I asked the cop on the stand if he would have given his wife a ticket under the same exact scenario, he said ‘no,’” Sanders explained.
After being told that he now owes the state of Texas several hundred dollars, or he will face jail time, or even possible police violence, Brett decided to pay his fine — but it was going to get paid on his terms — in pennies.
Below is the epic result his act of civil disobedience with a catch.
“It felt amazing to dump those pennies,” Sanders explained. “I highly recommend it as a stress management measure.”
At the end of the video, Sanders receives a call from the station telling him that he overpaid and they actually had some change for him. We asked Sanders if he plans on returning to retrieve that change, to which he replied, “Hell no.”
Since this video has come out, Sanders said he’s received some flack for “ruining that nice clerks day.” However, it was very unlikely that she had to collect all that loose revenue by herself, and, as Sanders put it, “she collects stolen money for a living.”


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text:
A charming and moving fairytale
By Philip Concannon
, 07 Nov 2004
After his latest play is a flop, JM Barrie(Johnny Depp) is struggling to find inspiration for his next effort. While writing in the park one afternoon, he meets Sylvia Davies(Kate Winslet), a widow, and her three children. He starts to spend an increasing amount of time with the family, delighting them with his imaginative games and flights of fancy. But his efforts are not appreciated by everyone, especially his social-climbing wife(Radha Mitchell) and Sylvia's tyrannical mother(Julie Christie).
Marc Forster's wonderful movie doesn't pretend to be anything like a biopic of Barrie or a true telling of how 'Peter Pan' came to be. Instead Forster and screenwriter David Magee play fast and loose with the facts, creating a witty, subtle and powerful celebration of innocence and imagination. Forster cleverly drops in little moments which will later appear in Barrie's most celebrated play, and the transitions between the reality and fantasy sequences are smoothly handled.
But it's the outstanding ensemble cast which makes 'Finding Neverland' such satisfying experience. Depp is in his element as Barrie, giving possibly his finest performance yet. An actor who has made a career from playing grotesques and oddballs, he makes a fully rounded character from Barrie and never puts a foot wrong. He's matched by the ever-excellent Winslet, who plays Sylvia as a strong-willed young woman, desperately keeping a lid on her vulnerability for the sake of her family.
Radha Mitchell, Julie Christie and Dustin Hoffman are all on fine form in their supporting roles, and Forster also gets fine performances from the young actors playing Sylvia's children. Freddie Highmore gives a hugely impressive display as Peter, the stubborn boy who will become the inspiration for Barrie's main character, and Joe Prospero, as his older brother, handles a difficult role with subtlety and skill.
'Finding Neverland' isn't a perfect film, taking one or two too many trips to invented worlds, but it's a supremely rewarding one. The emotional second half will ensure there isn't a dry eye in the house as the credits roll. A gorgeous, inspiring fairytale which is guaranteed to steal your heart.
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domain: artistic


text:
Re: VCF 7 Videos: Was: [midatlanticretro] Yay! Exhibit the first ....
- There's no way I could make it to the East coast.
It would be nice if someone made a decently extensive and thorough
(mini-) documentary (video) of all of the exhibits. (and the workshops)
You could even put it on a DVD and sell it to make some extra money for MARCH.
Plus it would document stuff for future reference. It should be done as
professionally as possible, which isn't that hard these days. You might
be able to find a local indie filmmaker to do it for the experience.
(mostly you just need a decent camera, decent lighting, and keep the
hand-held to a minimum) Some nice as-professionally-done-as-possible
photos would be good, too. (a 'real' photographer would make a big
difference in the composition of the shots, lighting, etc.)
- Bill D
... CRAV Computing Hobbyist : Classic/Retro/Antique/Vintage


text:
Cancer Council WA is pleased to announce the release of their Vaping Bill Advocacy Campaign Stakeholder Toolkit.
The Australian Government plans to introduce into Parliament a draft law which, if passed, will stop the supply of non-prescription vapes. Our Campaign aims to urge West Australians to tell their Federal MP to support the new laws. Whether they are a parent, teacher, health professional or a concerned member of the public, their voice matters now more than ever.
Please find attached the Campaign Stakeholder toolkit which includes:
- Information about the campaign
- Social media copy and images
- E-newsletter piece
To access the toolkit, click here:
For any questions please contact: email@example.com.

domain: news


UK Covid case deaths are on the rise with another 36,710 infections recorded in the last 24 hours.
Infections have increased by 40 per cent in a week, after 26,326 cases were reported on September 16.
The daily number of Covid deaths has increased by 182 today – up from 166 yesterday and 158 at the same time last week.
The total death toll since the beginning of the pandemic now stands at a grim 135,803.
There have also now been 7,565,867 infections of coronavirus since the beginning of the pandemic.
As of yesterday there were 48,674,154 first dose jabs administered and 44,600,070 second doses, with the total reaching 93,274,224.
It comes as experts have warned that a further rise in deaths will force the government into implementing further lockdowns.
Covid deaths currently account for around eight per cent of all deaths in the UK.
While the ONS says deaths are consistently lower for people who have been double vaccinated – overall the death toll in the UK is still on the up.
One expert has warned that if this number continues to increase then the government could be forced to introduce a ‘non-existent’ Plan C.
But Professor Neil Ferguson, the SAGE adviser dubbed “Professor Lockdown” argued another shutdown is unlikely thanks to vaccines.
He said he “very much doubts” another lockdown will be needed, as long as the vaccine booster rollout and jabs for kids go as planned.
Professor Ferguson admitted cases are likely to rise in the colder months as people socialise more indoors but said he is “moderately optimistic”.
Britain is currently in a good position in the fight against the virus – with deaths relatively low and the vaccines working, despite cases remaining high.
Testing for the virus is now also widely available – meaning that people can find out faster if they have the virus so in turn they can isolate and avoid spreading it to others.
Last week Professor Tim Spector from King’s College London, said that the government should go straight to Plan B in order to stop the NHS from crumbling.


A Decree No. 158, dated 12/06/1429H, issued by the Council of Ministers, has approved the General Plan of the Technical and Vocational Training Corporation, the plan included the following:
To effectively contribute to the economic, social and environmental development by providing high quality technical and vocational training for Saudi males and females to meet the local labor needs in the Kingdom to achieve international leadership and ensure independence and self-sufficiency.
- The Technical and Vocational Training Corporation objectives are:
• To license, evaluate and develop technical and vocational training programs for males and females according to quality and quantity needed by the labor market. And to enact rules and regulations governing their quality and also to supervise these programs.
• To conduct research and carry out projects necessary to follow up international technological developments in technical and vocational training.
• To participate in National programs that adopt transfer of technology as their policy, and support the Private sector.
- • To encourage the private sector to invest in technical and vocational training.
1. To admit the largest possible number of interested persons in technical and vocational training in order to attain sustainable development.
2. To qualify and develop national technical and vocational human cadres in accordance with the quantity and quality needed by the labor market.
3. To provide high quality and efficient training programs that qualifies the trainee for suitable employment.
4. To adapt to and deal with challenges and variables successfully by conducting studies.
5. To establish strategic partnerships with the private sector to implement technical and vocational programs.
6. To educate the public on the importance of technical and vocational fields and provide appropriate environment for lifelong training.
7. To ensure safe working environment at the Technical and Vocational Training Corporation.
8. To promote investment in private technical and vocational training.
9. To boost relationships and integration with the national training and educational institutions.
10. To expand advanced training fields that support national plans and take part in transfer of technology programs and enhance them.
Objectives Implementation Strategies:
- To train Saudi youths to take technical, vocational and professional jobs with the various Industrial, Agricultural, Commercial and general services) at both public or private sectors. In addition to training at colleges, institutes and centers and look forward to develop and raise the standard of technicians and professionals while on duty. This of course enables them to acquire advanced knowledge in science and technology both locally and internationally.
- To endeavor to train youngsters and illiterates who did not continue their academic education and organize special evening and morning programs for them according to their ages, so that they continue their education or practice technical work.
- To train Saudi national cadre for teaching and training.
- To direct investors to develop the structure of skills in order to widen the foundations of technical work in the Kingdom.
- To establish educational structure of a unified scale to support technical labor in coordination with organizations rehabilitation of human and the Ministerial Committee for Workforce.
- To support the vocational guidance and counseling to raise awareness of technical and vocational education through the concerned organizations with a better outcome for the Corporation's services, both technical and vocational training to achieve the desired goals.
- To conduct research and studies to address the problems of technical labor in the light of the needs of the labor market.


Streaming + Download
Includes unlimited streaming via the free Bandcamp app, plus high-quality download in MP3, FLAC and more.
This is the fastest of the bunch and probably the most diverse, it covers everthing from moombahton to acid and funk.
released December 7, 2014
all rights reserved


Sales at fashion website PrettyLittleThing set to hit £30m by the end of the year
The son of Boohoo.com founder Mahmud Kamani is following in his father’s footsteps after sales at his internet site PrettyLittleThing.com rocketed 500 per cent.
Sales are set to hit £30million by the end of the year – trouncing last year’s turnover of £5million.
Umar Kamani’s success follows the phenomenal growth of Boohoo.com, which floated on the London Stock Exchange last year and is valued at £376million.
Chic: The fashion website has seen a 500 per cent explosion in sales
PrettyLittleThing is popular with celebrities including Hollywood actress Lindsay Lohan and The X Factor winners Little Mix.
Most watched Money videos
- Bentley brings the comfort of a limo to their popular SUV
- McMurtry fan car sets new Goodwood Hill record as fastest car
- Ford unveils electric version of Britain's best-selling vehicle
- 1990's advert for the Vauxhall Cavalier Turbo 4x4
- Watch the BANNED Land Rover ad that 'misrepresented' parking sensors
- A rare 1955 Mercedes 300 SLR Coupe being driven at Goodwood
- Renault previews new family car powered by a hydrogen-electric system
- German car giant BMW launches its first ever M3 Touring model
- Ford unveils 2,000bhp electric Supervan its fastest transit yet
- One-of-a-kind Ford Capri sells for new record price of £75k
- Land Rover unveils its new £80,000 Range Rover Sport
- RM Sotheby's has sold a Mercedes for a record £115million


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Islands TourTravel — Travel / leisure
|About||We are Tour & Travel Company in Indonesia|
Our company are as enthusiastic about holiday as you are!
We are highly motivated and we will make sure you have the best holiday ever!
Feel Free to Contact Us
Phone +62 274 919 2080
pin BBM 7535ECFA
Our mission is to offer a small group travellers the holiday of a lifetime in Indonesia.
Our holidays will be delivered in a professional, caring and responsible manner ensuring we are the global leaders
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domain: travel


text:
Seoul National University Hospital Healthcare System Gangnam Center will always be your reliable health partner.
Located on the 38th - 40th floor of Gangnam Finance Center, the SNUH Healthcare System Gangnam Center offers accurate and reliable diagnosis by the experienced SNUH medical staff, state-of-the-art medical devices, lifelong integrated medical record management, and comfortable facilities to ensure accurate early detection and prevention of disease.
The entire faculty and staff at SNUH work together to deliver a personalized and integrated assessment of your health tailored to your specific needs and concerns in order to boost your health and longevity.
We promise you the most comfortable and satisfactory medical service.
Seoul National University Hospital Gangnam Center
President Jeong-Yeon CHO

domain: health


‘Very surprised’ is the best way I can say it after learning of the firing of Steelers Special Teams Coach Al Everest. I suppose there is much more to the story than we may ever know but the guy took a unit that was pretty awful and turned it into one that didn’t allow a return for TD. Sounds like this was simply a matter over a difference in opinion on how things should happen for the special teams and we know who wins thsoe arguments.
Even though there are things I take issue with when it comes to the Rooney’s, (most of them deal with Goodell), I thank God they are the owners of my team daily. After seeing the media storm created by Colts’ owner Jim Irsay on Twitter regarding a pending ‘big’ trade, I found myself grateful once again. Shut up Jim.
Another thing to be grateful for? Not having to hear Chris Berman call an NFL game as he did this week for ESPN. I was traveling but sadly was forced to endure some highlights. I can’t lie, I used to love Berman back in the ESPN infancy days when he would do SportsCenter with Bob Ley and Tom Mees (RIP) and he’d come up with those great names for guys. Of course I was young and a complete idiot then too. Please don’t allow him back in the booth. Ever.
Mike Wallace will report after the third preseason game I would think. He is playing the same game played by many who wanted more money in the past. Skip training camp to avoid injury then show up. Hope he heard DeSean Jackson’s comments about “not going 100%” last year.
According to the Sporting News, the NFL could stand to pay billions in concussion-related lawsuits. This ‘revelation’ was in a five-part series by SN and should come as absolutely no surprise. Why on Earth do you think Roger Goodell is trying to turn this league into a glorified flag football league for God’s sake? He’s trying to cover his ass over the violence of the game for the last 80 years! Quick, someone get my pills!
The Two-Minute Drill
- Arizona Head Coach Ken Whisenhunt said he “wasn’t ready to name a starter just yet.” That’s like a condemned man saying, “The electric chair or the firing squad?”
- Everyone thinks the Jets have an issue at quarterback. How about addressing that offensive line first? Yikes, they couldn’t protect a telephone pole.
- Keep an eye on Nick Foles, the Eagles’ rookie vying for the number two job. This kid from Arizona can flat-out wing it and has looked good so far in the preseason. With Mike Vick’s health always a question, he could see the field a lot in 2012.
- Browns’ rookie running back Trent Richardson said he expects to be ready to go for Week One. Silly Rookie, this is the Browns! Doesn’t he know that an alien spacecraft will land on him during pregame warm-ups injuring his knee again?
- Has it been two weeks since the Steelers last had a fight in practice? Stop the presses!
- We’re almost there folks. Week One of the 2012 NFL regular season!!


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Freshfields Bruckhaus Deringer Singapore managing partner Gavin MacLaren will leave the firm next year to join Australia’s Corrs Chambers Westgarth as CEO.
MacLaren will succeed John Denton, Corrs’ chief executive of 17 years, in July 2018. He will be based in Melbourne.
Denton, who has been a partner since 1996, will retire from the Australian firm and pursue a new career, according to a statement from the firm.
MacLaren, a transactions lawyer specializing in the energy sector, has advised on deals and projects across Asia, Australia and the Middle East. In 2016, he led a Freshfields team advising the Qatar Investment Authority as part of an investor consortium on a $6.7 billion acquisition of Australian freight logistics company Asciano Ltd.
MacLaren joined Freshfields in 2012 as the Magic Circle firm planned to relaunch its Singapore office. Before that, he had been a Melbourne-based partner with Australian firm Allens for a decade, during which time he led the firm’s Asia practice and headed its Singapore office between 2003 and 2009.
In a statement, Freshfields wished MacLaren well, saying the firm may have the opportunity to work with him in the future.
“We … wish him the best for the next chapter of his career,” the firm said in a statement. “Corrs Chambers Westgarth is a member of the firm’s network of StrongerTogether law firms, so we expect that we will have the opportunity to work with Gavin again in the future.”
It was not clear at press time who will take over as Freshfields’ Singapore managing partner. Freshfields Asia managing partner Georgia Dawson and Asia head of corporate Stephen Revell both currently divide their time between Singapore and Hong Kong.
Corrs has 650 lawyers, including 120 partners, across offices in Sydney, Melbourne, Brisbane, Perth and Papua New Guinea’s Port Moresby.


David Zayas Is Sal Maroni on ‘Gotham’
The former co-star of “Dexter” will play one of the biggest mob bosses in...
The Top 10 TV Cosplayers of Comic-Con 2014
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13 Sequels That Never Happened
Announcing Guardians of the Galaxy 2 this early could be dangerous, as proved by...
Is Batman v Superman: Dawn of Justice a Real Movie?
We have a little… but not much. What is the story? CraveOnline muses on...
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Writers Brenden Fletcher and Becky Cloonan join Editor Mark Doyle to talk about what...
Comic-Con 2014: ‘Arrow’ Season 3 Villain Revealed
One of Batman’s greatest enemies is coming to Starling City.
Comic-Con 2014: 75 Years of Batman
Frank Miller, Jim Lee, Geoff Johns, Scott Snyder and Dan DiDio on the best...
Comic-Con 2014: First Picture of Ben Affleck as Batman Revealed
Warner Brothers shows you the stubble beneath the mask that is Ben Affleck as...
Comic-Con 2014: Heath Ledger’s Joker Immortalised In Lego
Lego to unveil their take on Aussie actor’s iconic role at Comic-Con.
Comic-Con 2014: The 10 Most Anticipated TV Panels
Our guide to the best of this year’s television panels at Comic-Con International.
TCA Interview: Ben McKenzie on ‘Gotham’
The new Jim Gordon of Fox’s Batman prequel, “Gotham,” talks about the show’s film...
DC Announces Its Batman Plans For Comic-Con
Frank Miller, Jim Lee, Scott Snyder and more will headline a Batman 75th Anniversary...
Exclusive Preview: Batman Eternal # 14
Is this the last stand of The Penguin?
Exclusive Preview: Batman Beyond 2.0 Chapter 24
Batman Beyond gets his rematch with Lord Superman!
The 12 Best Cars Made for Movies
When a plain old-fashioned car just wasn’t enough, these films invented their own.
Hellboy’s Greatest Crossover Adventures
Our look back at Hellboy’s most memorable team-ups of the last 20 years.
My First Time: Batman (1989)
One of our critics watches Tim Burton’s Batman for the first time (what?! how?!)...
Watch The ‘Gotham’ Villains Teaser Trailer
The future Catwoman and Penguin share the spotlight with Fish Mooney in the new...
First Impressions: ‘Gotham’ Season 1 Episode 1
Our thoughts on the pilot episode of Fox’s upcoming Batman prequel series, “Gotham.”


text:
Operating room (OR) costs are on the rise, with a single minute in the OR costing a hospital between $22 and $133 per minute. Providing patients with timely care is of the utmost importance, as even a slight delay in start time can cost healthcare organizations hundreds of thousands, if not millions, in lost revenue annually.
John Muir Health looked to reduce wasted time in the OR, focusing on first case on-time starts (FCOTS) as an important metric for improvement. However, OR teams were largely unaware of the importance of FCOTS, let alone how to improve the rates. In the OR, it was not uncommon for data to be three to six months old before being available for review, limiting the ability to use the data for improvement. As it was common for only 10 to 20 percent of cases to start on time in its OR, John Muir Health focused on providing the data needed to educate staff on the reasons behind delays, so that start times could be improved.
ORs are a critical source of patient care services and income generation for hospitals. However, ORs are also a source of high costs, with a single minute in the OR costing a hospital between $22 and $133 per minute.1,2 As a result, even a slight delay in start time can cost organizations hundreds of thousands, if not millions, of dollars annually.
First case on-time starts (FCOTS) are an important OR metric, providing insight on how timely and efficient care processes may be. First case delays create a ripple effect on OR operations for the remainder of the day, delaying subsequent cases, frustrating patients, decreasing efficiency, and increasing costs.3
A leader in healthcare in the San Francisco Bay Area, John Muir Health is a not-for-profit integrated system of doctors, hospitals, and other services. John Muir Health looked to reduce first case delays and improve its FCOTS as a means to improve OR efficiency and reduce unnecessary costs.
John Muir Health’s surgical teams knew they needed to be more efficient to better meet patient care demands, but teams lacked the data to help them understand their performance. Operations in the OR were not data-driven, and it was not uncommon for data to be two to three months old before being available for review, limiting the ability to use the data for improvement efforts.
Surgical teams were largely unaware of the economic drivers within the OR, meaning staff was not fully aware of the importance of maintaining a high rate of FCOTS. While teams had started to discuss key performance indicators (KPIs), it had not been a priority. As a result, it was common for only 10 to 20 percent of cases in the OR to start on time.
Leadership at John Muir Health identified the need to improve OR efficiency. But before they would be able to do so, the teams needed actionable, timely data that could be used to inform improvement efforts.
To transform into a data-driven operation, John Muir Health leveraged the Health Catalyst® Analytics Platform and broad suite of analytics applications, specifically the Department Explorer: Surgical Services analytics application, to better understand and improve operational efficiency within the OR.
Department Explorer: Surgical Services is an analytics tool that provides managers multiple views of data regarding operational efficiency utilization, and case-level details specific to the OR (see Figure 1). This information helps users to better analyze specific OR data, such as patient prep, anesthesia prep, room turn-around, room and staff scheduling, and procedure data so that potential improvements can be identified.
Using the analytics application, surgical services leadership was able to drill into OR KPIs, including FCOTS (see Figure 2). For the first time, leadership was able to slice and dice the data to understand the reasons for delays. Leaders were able to easily identify outliers, and opportunities for improvement.
With improved access to actionable data, surgical services leadership began engaging nursing staff and surgeons to understand their performance data and use it for improvement. First, leaders socialized the data with the team, reviewing and validating that data were correct. During this process, they identified an opportunity to improve delay codes, ensuring hospital staff was using a small list of delay codes that were meaningful.
Leaders implemented processes to ensure timely, actionable data was shared with nursing staff and surgeons on a regular basis. The medical director engaged his colleagues in peer-to-peer conversations about performance, identifying opportunities for improvement and garnering their support to participate in improvement initiatives. The executive director for surgical services and other nursing leaders engaged their staff in similar conversations, providing them with the opportunity to question the data and give feedback based on their experience.
Improving FCOTS required a large number of key stakeholders perform work in concert with one another, coordinating complex care activities over a short period of time with the goal of the patient arriving in the OR as scheduled. This meant surgical teams, the patient, and the room and surgical equipment are all available and ready on time. Because such a large number of people are involved in care, leadership needed to meet with and engage a large number of stakeholders to implement changes, and then follow up with data to demonstrate the impact those changes had on performance.
Leaders regularly meet with various physician offices, engaging surgeons, directors, and office managers in improvement efforts, using data from the analytics platform to provide feedback about performance. The team used a data-driven approach to identify several process changes that improved the ability to start the first cases on time.
The pre-op team took greater responsibility for ensuring patients from the ICU arrived on time, taking ownership of the first case ICU transport. Pre-op nursing staff also took on greater responsibility for breathing treatments, ensuring patients receive needed treatments in a timely manner.
The data indicated that one factor contributing to late starts was patients who also required chemotherapy. Pharmacy staff would bring the chemotherapy medications to pre-op around 7:45 a.m., inadvertently contributing to delays. Leaders were able to provide the pharmacy team with this data, sharing the importance of the FCOTS as a KPI and as an economic driver. The pharmacy subsequently adjusted staff arrival time, bringing the chemotherapy medications to the OR earlier in the morning, helping to ensure on-time first case starts.
First case nerve blocks were also a source of delays. The teams now huddle each day, identifying how many first case nerve blocks are scheduled for the next day, adjusting staffing as needed to ensure adequate staff and an on-time start. Lastly, when patients arrived in the cold OR, they would indicate they needed to use the restroom. Pre-op nursing staff now take all patients who are able to use the restroom 30 minutes prior to the case start time.
The data indicated that delays in room set up, particularly for large cases, were negatively impacting the ability to start on time. To prevent this delay, the night shift charge nurse now works with staff to set up rooms more completely, preventing a delay in the morning.
When discussing opportunities for improvement, some staff shared that when they had large cases, they were arriving early to set up. Leadership invited all staff to have more control over their work, indicating that they were supportive of staff with large cases arriving early and clocking in, so they can be appropriately compensated for their work.
After sharing the FCOTS data with providers and allowing adequate time for teams to adjust to new expectations for an on-time start, leadership began communicating surgeon specific performance through letters directly to surgeons. Over time, the individual letters changed to departmental letters. All department members are now able to see their performance in relation to their peers.
The team convenes for a huddle each afternoon, using data from the analytics application to review daily performance. They review the reason for any delays, actively engaging in identifying and implementing changes to prevent similar delays in the future.
John Muir Health is transforming into a data-driven OR, and its efforts to improve FCOTS is yielding the desired results. FCOTS data has been incorporated into daily workflows, supporting ongoing, active management of the start times. To date, and as a result of this improvement work, John Muir Health has successfully:
While initially focused on improving FCOTS metrics, timely actionable data has resulted in:
“To improve operations, you need performance data that is immediately available, so that you can provide people with immediate feedback. Department Explorer: Surgical Services allows us to monitor our performance and provide immediate feedback to our teams.”– Ryan B. Green, M.D., Ph.D.
Medical Anesthesia Consultants
John Muir Health plans to continue to use a data-driven approach to improve performance. The health system’s leadership is continuing to work on decreasing waste, making processes less burdensome, and increasing OR efficiency.

domain: medical


|Publication number||US6267104 B1|
|Application number||US 09/528,178|
|Publication date||Jul 31, 2001|
|Filing date||Mar 17, 2000|
|Priority date||Mar 18, 1999|
|Also published as||EP1036935A1, EP1036935B1|
|Publication number||09528178, 528178, US 6267104 B1, US 6267104B1, US-B1-6267104, US6267104 B1, US6267104B1|
|Original Assignee||Institut Francais Du Petrole|
|Export Citation||BiBTeX, EndNote, RefMan|
|Patent Citations (15), Referenced by (25), Classifications (23), Legal Events (4)|
|External Links: USPTO, USPTO Assignment, Espacenet|
The present invention relates to the field of engines with direct or indirect injection of liquid fuel into at least one combustion chamber.
The fuel can be liquefied petroleum or liquefied natural gas, dimethylether (DME), ethylal, methylal or diethylether (DEE).
It is well-known to use these fuels in admixture with the intake air. Patent application WO 96/35,863 describes a system based on this concept where air and liquefied fuel are mixed upstream from the combustion chambers as a complement to a conventional gasoline injection system (of “common rail” type here). However, fuel vaporization problems are observed with this type of supply. To overcome this problem, this prior art proposes mixing the liquid fuel with the intake air in a place relatively distant from the combustion chamber; the temperatures are thus less high and better vaporization can be performed.
Recent developments have allowed to introduce the fuel in liquid form, directly or mixed with air, into the combustion chamber. This requires pressure maintenance in all the supply system, from the tank to the vaporization point: combustion chamber in the case of direct injection or intake pipes for indirect injection.
An important problem then consists in maintaining and controlling the liquid state by means of the pressure in all of the supply system, whatever the running conditions of the engine and the outside conditions. In fact, the liquefaction pressure variation can range from 1 to 18 bars according to the working temperature of the fuel.
The fuel tank is generally designed to withstand this type of pressures so that storage in the liquid state does not pose problems at this level of the supply circuit.
However, this is not the case in the other parts of the supply circuit and notably between the tank and the injectors.
More precisely, a problem arises when the engine is restarted after prolonged stoppage of the engine.
This phenomenon can be explained as follows: the injectors being permeable to the fluid, a slight liquid leak occurs when the engine is stopped, which lowers the pressure in the supply system and therefore changes the state of the fuel that goes from the liquid to the gaseous state. The leak is thus sustained.
After a more or less long period of immobilization of the vehicle, which depends on the storage conditions and on the structure of the injectors, the (originally liquid) fuel contained in the supply system can thus be vaporized and transferred to the engine, either directly into the combustion chamber or via the intake.
When the engine is restarted, the vaporized fuel is present in large amounts in the combustion chamber, which generates a non-flammable mixture (case of liquefied petroleum gas LPG) or self-ignition (case of dimethylether DME).
A known solution consists in isolating each injector of the rail by a solenoid valve when the vehicle is stopped. However, this solution is complex, bulky and expensive.
In order to solve the problems linked with bad pressure maintenance in the supply system of such engines, the present invention proposes an innovative solution, both simple and reliable.
It consists, when the engine is stopped, to isolate the part of the supply system comprising the injectors by any suitable means. The liquid fuel contained in the part thus isolated can then be drained into a suitable storage system (liquid or gaseous).
This concept thus prevents any liquid fuel leak into the engine and therefore allows good starting of the engine after a certain stoppage.
The object of the present invention thus is a system intended for pressure supply of liquid fuel to at least one combustion chamber of an internal-combustion engine, comprising a tank intended for pressure storage of the liquid fuel, means allowing pressure injection of the fuel into at least one combustion chamber, a line between said tank and said injection means, a pump placed in the tank or on said line, a pressure regulator placed in said tank or on said line, a capacity (canister) placed on a by-pass of the line towards an intake system (A) of the engine and intended for storage of the gaseous fuel, fuel injection being performed directly or not into the combustion chamber(s).
According to the invention, the system further comprises a means for isolating the injection means in relation to the tank and means for draining the injection means, placed on said by-pass, upstream from said capacity.
According to an embodiment of the invention, the injection means consists of at least one rail comprising each several injectors.
According to a particular embodiment of the invention, the system further comprises a return line between the injection means and the tank.
More precisely, the isolation means can consist of at least two solenoid valves placed respectively on the line and on the return line, on either side of the injection means.
Without departing from the scope of the invention, the isolation means can consist of a solenoid valve placed on the line between the tank and the by-pass.
In accordance with the invention, the system further comprises means for controlling the isolation means according to the engine stoppage time and conditions, such as the pressure and/or the surrounding temperature.
Other features, details and advantages of the invention will be clear from reading the description hereafter, given by way of non limitative examples, with reference to the accompanying drawings wherein:
FIG. 1 is a diagram of a supply system according to an embodiment of the invention, and
FIG. 2 is a diagram of a supply system according to another embodiment of the invention.
FIG. 1 shows a liquid fuel supply system according to a version of the invention. It essentially comprises a tank 1 that stores and maintains the fuel under pressure.
A line 3, also under pressure, starts from tank 1 and opens onto liquid fuel pressure injection means 2 that open either directly into combustion chambers or into the intake system of the engine.
A “common rail” type system can be used as injection means 2. This type of injector advantageously allows very precise fuel proportioning in time and in space. It comprises a series of injectors 2′. The flexibility of use is highly appreciated by motormen and it can be favourably integrated within the scope of the present invention.
The supply system further comprises a pump 4 placed either in tank 1 or on supply line 3. A pressure regulator 5 is also provided either in tank 1 (FIG. 2) or on line 3 (case of FIG. 2).
A by-pass line 7 is furthermore provided in branch connection with line 3 downstream from injection means 2 in relation to the direction of circulation of the fuel in line 3. By-pass line 7 opens onto intake system A of the engine.
A canister type means 6 intended for gaseous fluid storage is placed on line 7.
According to the embodiment of FIG. 1, a return line 10 connects injection means 2 and tank 1. Pressure regulator 5 can be arranged on this line 10.
According to the invention, means 8 intended to isolate injection means 2, 2′ in relation to the supply circuit are provided.
According to FIG. 1, means 8 are placed on either side of injection means 2.
In accordance with FIG. 2, isolation means 8 are arranged on line 3 upstream from the branch connection of line 7.
Furthermore, according to the embodiment of FIG. 2, line 7 is branch connected upstream from injection means 2.
Means 8 can preferably consist of solenoid valves that can be controlled according to the engine stoppage conditions: duration, temperature, pressure.
Furthermore, a drain means 9 such as a solenoid valve is provided on by-pass line 7 just upstream from canister 6.
Thus, during prolonged stoppage of the engine, solenoid valves 8 are activated so as to isolate the part of the supply system comprising injectors 2′. Drain means 9 is thereafter activated so as to lower the pressure in the part of the system comprising injectors 2, 2′ and by-pass 7. The fuel contained in this part of the supply system then changes from the liquid to the gaseous state.
Draining can thus be performed for the fuel towards canister 6. Emptying this “critical” zone of the supply system prevents fuel leakage into the engine. The canister can for example consist of activated charcoal allowing adsorption of the gaseous fuel.
The engine can thus be restarted after closing drain means 9 and reopening solenoid valves 8. This allows to overcome the drawbacks of the prior art. During restarting, the fuel trapped in canister 6 can be discharged to intake A and reused for combustion.
|Cited Patent||Filing date||Publication date||Applicant||Title|
|US5033444||Sep 4, 1990||Jul 23, 1991||Kaufman Ray L||Liquid butane fuel injection for internal combustion engines|
|US5074272 *||Dec 7, 1989||Dec 24, 1991||Ashland Oil, Inc.||Process and apparatus for reducing port fuel injector deposits|
|US5327872 *||Sep 28, 1993||Jul 12, 1994||Fuji Jukogyo Kabushiki Kaisha||Fuel pressure control method for high pressure direct fuel injection engine|
|US5373829 *||Oct 30, 1992||Dec 20, 1994||Bayerische Motoren Werke Ag||Fuel supply system of an internal-combustion engine|
|US5471962 *||May 4, 1994||Dec 5, 1995||Nippondenso Co., Ltd.||Fuel supply system for internal combustion engines|
|US5558068 *||May 26, 1995||Sep 24, 1996||Zexel Corporation||Solenoid valve unit for fuel injection apparatus|
|US5598817 *||Sep 8, 1994||Feb 4, 1997||Mitsubishi Jidosha Kogyo Kabushiki Kaisha||Fuel feeding system for internal combustion engine|
|US5758622 *||Feb 18, 1997||Jun 2, 1998||Robert Bosch Gmbh||Process and device for controlling an internal combustion engine|
|US5775281||Jun 21, 1995||Jul 7, 1998||The Energy Research And Development Corporation||Determination of heat soak conditions|
|US5970957 *||Mar 5, 1998||Oct 26, 1999||Ford Global Technologies, Inc.||Vapor recovery system|
|US6021763 *||Oct 17, 1997||Feb 8, 2000||Unisia Jecs Corporation||Fuel supply apparatus for a direct injection gasoline internal combustion engine|
|JPS5848768A *||Title not available|
|JPS57200663A *||Title not available|
|WO1992008888A1||Nov 20, 1991||May 29, 1992||Biocom Pty. Ltd.||A dual fuel injection system and a method of controlling such a system|
|WO1996035863A1||May 6, 1996||Nov 14, 1996||The Energy Research And Development Corporation||Liquid fuel injection system|
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US6912983 *||Oct 3, 2003||Jul 5, 2005||Bosch Automotive Systems Corporation||Fuel injection device|
|US6959697 *||Oct 14, 2004||Nov 1, 2005||Toyota Jidosha Kabushiki Kaisha||Fuel supply system for internal combustion engine|
|US7007670||Dec 3, 2004||Mar 7, 2006||Bosch Automotive Systems Corporation||Fuel injection device|
|US7066152 *||Sep 3, 2004||Jun 27, 2006||Ford Motor Company||Low evaporative emission fuel system depressurization via solenoid valve|
|US7201128 *||Jun 22, 2005||Apr 10, 2007||Daimlerchrysler Ag||Fuel supply system for internal combustion engine with direct fuel injection|
|US7222613||Jul 31, 2003||May 29, 2007||Geoffrey Russell Turner||Fuel delivery system|
|US7246606||Aug 8, 2003||Jul 24, 2007||Isuzu Motors Limited||Fuel return device for internal combustion engine|
|US7383804 *||Nov 9, 2006||Jun 10, 2008||Robert Bosch Gmbh||Procedure to recognize a depressurized fuel system|
|US7506638 *||Dec 11, 2006||Mar 24, 2009||Geoffrey Russell Turner||Fuel delivery system|
|US8196567 *||May 28, 2010||Jun 12, 2012||Ford Global Technologies, Llc||Approach for controlling fuel flow with alternative fuels|
|US20040069278 *||Oct 3, 2003||Apr 15, 2004||Kenji Okamoto||Fuel injection device|
|US20050092302 *||Oct 14, 2004||May 5, 2005||Toyota Jidosha Kabushiki Kaisha||Fuel supply system for internal combustion engine|
|US20050115533 *||Dec 3, 2004||Jun 2, 2005||Kenji Okamoto||Fuel injection device|
|US20050224057 *||Aug 8, 2003||Oct 13, 2005||Isuzu Motors Limited||Fuel return device for internal combustion engine|
|US20050235962 *||Jun 22, 2005||Oct 27, 2005||Normann Freisinger||Fuel supply system for internal combustion engine with direct fuel injection|
|US20060048752 *||Sep 3, 2004||Mar 9, 2006||Visteon Global Technologies, Inc.||Low evaporative emission fuel system depressurization via solenoid valve|
|US20060124112 *||Jul 31, 2003||Jun 15, 2006||Turner Geoffrey R||Fuel delivery system|
|US20070079815 *||Dec 11, 2006||Apr 12, 2007||Geoffrey Turner||Fuel delivery system|
|US20070101973 *||Nov 9, 2006||May 10, 2007||Robert Bosch Gmbh||Procedure to recognize a depressurized fuel system|
|US20070144490 *||Dec 21, 2006||Jun 28, 2007||Magneti Marelli Powertrain S.P.A.||Control method of a common-rail type system for direct fuel injection into an internal combustion engine|
|US20110168133 *||May 28, 2010||Jul 14, 2011||Ford Global Technologies, Llc||Approach for controlling fuel flow with alternative fuels|
|EP1541858A1 *||Aug 8, 2003||Jun 15, 2005||Isuzu Motors Limited||Fuel return device of internal combustion engine|
|EP1543231A1 *||Jul 31, 2003||Jun 22, 2005||James Richard Hunt||Fuel delivery system|
|WO2004016934A1 *||Aug 8, 2003||Feb 26, 2004||Isuzu Motors Limited||Fuel return device of internal combustion engine|
|WO2004018862A1 *||Jul 31, 2003||Mar 4, 2004||Geoffrey Russell Turner||Fuel delivery system|
|U.S. Classification||123/516, 123/527, 123/179.17|
|International Classification||F02M25/08, F02M55/00, F02M47/00, F02M21/02, F02M69/46, F02M37/20, F02M63/02|
|Cooperative Classification||F02M21/0239, F02M21/0287, F02M21/0212, F02M21/0245, F02M21/0221, Y02T10/32, F02M69/462, F02M25/089, F02M63/0225|
|European Classification||F02M69/46B, F02M21/02, F02M63/02C, F02M25/08L|
|Mar 17, 2000||AS||Assignment|
Owner name: INSTITUT FRANCAIS DU PETROLE, FRANCE
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:MONNIER, GAETAN;REEL/FRAME:010637/0407
Effective date: 20000203
|Feb 16, 2005||REMI||Maintenance fee reminder mailed|
|Aug 1, 2005||LAPS||Lapse for failure to pay maintenance fees|
|Sep 27, 2005||FP||Expired due to failure to pay maintenance fee|
Effective date: 20050731


Wall-mounted phones are available at Best Buy, Walmart and Amazon.com. As of November 2015, the Cortelco ITT-2554-V-IV corded mini wall phone is available at Best Buy. This phone has a volume control and supports one phone line.
The AT&T TL-210 Trimline phone is available at Walmart, as of November 2015. It is wall mountable and offers a programmable speed dial for up to 12 telephone numbers. Its three one-touch memory buttons let users dial the stored telephone numbers with a single touch.
The black Crosley CR55-BK wall phone is available at Amazon.com. This phone has a retro look and features push-button technology. It offers both ringer volume control and earpiece volume control.


text:
Outbound FDI Rises 25 Percent over First 11 Months, Ministry Says
The country's outbound foreign direct investment totaled US$ 62.5 billion over the first 11 months of the year, year-on-year growth of 25 percent, statistics released by the Ministry of Commerce on December 18 show.
Among investment targets, the United States saw a mild increase. China's all-time FDI in the United States reached more than US$ 9 billion in 2011, and in the first 11 months of 2012, Chinese firms invested another US$1.1 billion, or 13 percent more than in the same period a year earlier, ministry data shows.
- China Releases Guiding Policy on Reform Tied to Government Spending
- China's Stimulus Bond Program Faces Effectiveness Test
- Why Official Claim on Services Driving China's Economy is Misleading
- Kobe Bryant Invests in China Education Firm
- China Contractor Gets Second Chance at Bahamas Luxury Hotel
- Alibaba Pictures Expands Into Cinemas
- Despite Gains in HDI, China Needs More Reform for Inclusive Growth, UN Says
- CSRC Beefs up Internal Disciplinary Inspection with New Committee
- Insurance Regulator Eyes Crackdown on Short-Term Policies
- China Telecom H1 Profit up 6.3 Pct on Strong 4G Subscriber Growth
- Sign up to receive our free daily newsletter
- China Edges Closer to a Liquidity Trap
- First China Made Bullet Train Makes Maiden Trip
- Souring Business, Xenophobia Makes China Dream Lose Its Appeal for African Migrants
- China to Bring Back Equity Incentives for SOE Employees
- Farewell Medal Mania, Hello Sports Reform
- Dalian Wanda's Property Arm To Delist from Hong Kong in September
- China Behind on Plans to Trim Overcapacity
- Alibaba Rakes in Millions Selling Co-branding Rights to Double 11 Gala
- Can Baseball Finally Hit a Home Run in China?
- Car-Hailing Firms Try New Business Frontiers


text:
The World of Work and COVID- 19 Crisis Economic, Social and Labour Relations Implications Research
The international seminar held by the Industrial Relations Research Association of Israel, in partnership with Friedrich-Ebert-Stiftung and the International Labour Organization, focused on the humanitarian, social, and economic crises stemming from the COVID health pandemic.
Research and edited by Adv. Joseph Gattegno
Published: December 2020
>> Click here to view the conference video
>> Click here to download a digital copy of the publication in English
>> Click here to download a digital copy of the publication in Hebrew
Categories: Labor Relations, Social Justice

domain: library


text:
BUT THAT'S OK, the breeder tells us. His "breeding facility" was licensed by the USDA.
IS THAT OK WITH YOU?
IT'S NOT OK WITH US!
"Why does San Diego need any new legislation? We already have humane laws, and the USDA regulates breeding facilities."While it is true that the USDA does regulate some pet breeding facilities through the provisions of the Animal Welfare Act, USDA officials are also frustrated in enforcement because:
The Animal Welfare Act again provides only the barest of minimum of protection for the animals. There are only around 100 USDA inspectors to cover thousands of licensed facilities throughout the nation.
Existing laws, as they stand, just are NOT doing the job. We need to stop the sale of puppies in pet stores in order to protect the breeding dogs and the puppies as well as consumers.
JOIN US! SUNDAY FEB. 19 and SUNDAY FEB.26
Noon - 2 PM
at Puppy Star's
6167 Balboa Ave.
THESE DATES ARE SPECIAL!
WE ARE CALLING ALL RESCUE DOGS TO
JOIN US AND LINE BALBOA AVE.
IF YOU HAVE A DOG AVAILABLE FOR ADOPTION
BRING IT TOO!
SIGNS SHOULD SAY ADOPT ME OR RESCUED
We will have protesters directly in front of the store with photos of shelter dogs who could not be saved because they were not adopted.

domain: pet


text: Published 29 December 200830 December 2008 · Main Posts Palestinians don’t count Jeff Sparrow What’s happening in Gaza would not be possible in any other context. But the Palestinians have been demonised so long that there’s a sizeable chunk of the political class prepared to justify any action against them. In Salon today, Glenn Greenwald takes as an example the output of the execrable Marty Peretz, the editor of the New Republic, who described the reaction in Gaza to the hundreds of deaths as ‘whining’. Any public figure in the US who mocked Israelis mourning their dead as ‘whiners’ would promptly face dismissal — and rightly so. But, as we saw in Iraq, Arab deaths simply don’t count. Greenwald continues: One can travel from the farthest right fringe of the GOP to the heart of the Democratic Party leadership and hear exactly the same thing: Israel is always right. Israel must not be criticized. Israel never bears any blame. Any action taken by Israel is justified. No matter the situation, that just gets repeated over and over like some hypnotic bipartisan mantra. How different is it in Australia? Not very. The most common spin on the looming full-scale assault on Gaza holds that Israel is merely responding to the Hamas rocket launches that violated an earlier cease fire. Even on its own terms, this is simply not true. Here’s Zvi Barel writing in Haaretz. Six months ago Israel asked and received a cease-fire from Hamas. It unilaterally violated it when it blew up a tunnel, while still asking Egypt to get the Islamic group to hold its fire. Are conditions enabling the return of a ceasefire no longer available? Hamas has clear conditions for its extension: The opening of the border crossings for goods and cessation of IDF attacks in Gaza, as outlined in the original agreement. Later, Hamas wants the cease-fire to be extended to the West Bank. Israel, for its part, is justifiably demanding a real calm in Gaza; that no Qassam or mortar shell be fired by either Hamas, Islamic Jihad or any other group. Essentially, Israel is telling Hamas it is willing to recognize its control of Gaza on the condition that it assumes responsibility for the security of the territory, like Hezbollah controls southern Lebanon. It is likely that this will be the outcome of a wide-scale operation in the Gaza Strip if Israel decides it does not want to rule Gaza directly. Why, then, not forgo the war and agree to these conditions now? More importantly, the recent attacks need to be understood in the context of the Israeli blockade of Gaza, of which, in some respects, they are simply a continuation. In August, Amnesty International wrote: The blockade imposed by Israel on the Gaza Strip over a year ago has left the entire population of 1.5 million Palestinians trapped with dwindling resources and an economy in ruins. Some 80 per cent of the population now depend on the trickle of international aid that the Israeli army allows in. This humanitarian crisis is man-made and entirely avoidable. Even patients in dire need of medical treatment not available in Gaza are often prevented from leaving and scores of them have died. Students who have scholarships in universities abroad are likewise trapped in Gaza, denied the opportunity to build a future. The Israeli authorities argue that the blockade on Gaza is in response to Palestinian attacks, especially the indiscriminate rockets fired from Gaza at the nearby Israeli town of Sderot. These and other Palestinian attacks killed 25 Israelis in the first half of this year; in the same period Israeli forces killed 400 Palestinians. However, the Israeli blockade does not target the Palestinian armed groups responsible for attacks – it collectively punishes the entire population of Gaza. In April 2008, Robert Serry, the UN Special Coordinator for the Middle East Peace Process and Personal Representative of the UN Secretary General, called on Israel to restore fuel supplies to Gaza and allow the passage of humanitarian assistance and commercial supplies. “The collective punishment of the population of Gaza, which has been instituted for months now, has failed,” he said. […] Israel has banned exports from Gaza altogether and has reduced entry of fuel and goods to a trickle – mostly humanitarian aid, foodstuff and medical supplies. Basic necessities are in short supply or not available at all in Gaza. The shortages have pushed up food prices at a time when people can least afford to pay more. A growing number of Gazans have been pushed into extreme poverty and suffer from malnutrition. Some 80 per cent of the population now depends on international aid, compared to 10 per cent a decade ago. The restrictions imposed by Israel have resulted in higher operational costs for UN aid agencies and humanitarian organizations. Food assistance costs the United Nations Relief and Works Agency (UNRWA) US$20 per person per day compared to less than US$8 in 2004. Gaza’s fragile economy, already battered by years of restrictions and destruction, has collapsed. Unable to import raw materials and to export produce and without fuel to operate machinery and electricity generators, some 90 per cent of industry has shut down. The fuel shortage has affected every aspect of life in Gaza. Patients’ hospital attendance has dropped because of lack of transport and universities were forced to shut down before the end of the school year as students and teachers could not continue to travel to them. Fuel-powered pumps for wells and water distribution networks are often not working. Medical facilities in Gaza lack the specialized staff and equipment to treat a range of conditions, such as cancer and cardiovascular disease. In addition, hospitals are now under ever greater pressure, as they face shortages of equipment, spare parts and other necessary supplies as a result of the blockade. Note, if you will, that the above comes not from some wild-eyed Leftist manifesto but from the most respected human rights organisation in the world. Yet its description of an ongoing crime (collective punishment) against the Palestinian people prompted no international response whatsoever. Imagine if the Palestinians had developed a secret weapon by which they could inflict malnutrition on the population of Israel and prevent sick Israelis receiving treatment. Now imagine that the Palestinians deployed this machine – but declared they would stop doing so when Israel elected a new leadership. Does anyone really suppose that the world would remain as indifferent as it did to the Gaza blockade? We might ask the same question about the recent attacks. Here’s another Israeli account of the carnage: Training camps of the Izz-al Din al-Qassam and interrogation and detention centers were deserted when they were bombed. But police centers in the Strip, which give services to people, were teeming. No one believed that they would be bombed. In the afternoon, they were still looking for bodies in the debris. Khalil Shahin rushed to the police station in the center of the Strip. “A huge building, and all of it on the floor,” he said. Some 30 people were killed there. He knew that his nephew, a civilian, was killed when he went to clear up some matter at the station. At first, teacher Umm Salah thought the explosion was a sonic boom. The whole building shook, all the glass, but the smoke and the clouds of dust, and the wails of ambulances, made clear that something much more horrible had taken place. The glass wounded a number of pupils. There were those who cried, there were those who were silent. She found her son in the maelstrom in the street. He had been taking a math test when the bombing began. They went back home together, finding his younger brother with their 70-year-old grandmother. The grandmother tried to hide her fear as she took care of her grandchildren. “There’s been no electricity, nor gas, nor flour or bread nearly all of the past week,” Umm Salah said. “And suddenly the electricity came back. I turned on the television, I saw the images, I turned it off and sent the kids to do their homework.” This targeting of police stations – basic pieces of civil infrastructure – has been elided into the official narrative of precision strikes against the Hamas leadership. Would anyone accept that ordinary American policemen were responsible for the decisions of George W. Bush? Of course not. But when it comes to Arabs, the rules are, as always, entirely different. Jeff Sparrow Jeff Sparrow is a Walkley Award-winning writer, broadcaster and former editor of Overland. More by Jeff Sparrow › Overland is a not-for-profit magazine with a proud history of supporting writers, and publishing ideas and voices often excluded from other places. If you like this piece, or support Overland’s work in general, please subscribe or donate. Related articles & Essays First published in Overland Issue 228 10 November 202311 November 2023 · Subscriberthon 2023 On the final day of Subscriberthon, Overland’s most important members get to have their say Editorial Team BORIS A quick guide to another year of Overland, from your trusty feline, Boris. I liked the ginger cat story, though it made my human cry. I liked the talking cat, too, but I’m definitely in the “not wasting my time learning to talk” camp. But reading is good. And writing is fun, though it’s been challenging […] 1 First published in Overland Issue 228 9 November 20239 November 2023 · Subscriberthon 2023 On the second-last day of Subscriberthon, Overland’s co-chief editor Evelyn Araluen speaks truth to power Editorial Team To my friends and comrades, I’m not sure if there’s language to communicate how this last month has utterly changed me. This time a few weeks ago the busyness and chaos of bricolage arts and academic labour had so efficiently distracted me from my anxiety about the upcoming referendum that I forgot to prepare myself for its inevitable conclusion.


text:
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domain: economics


text:
Omega 3 is good for the brain. Is it good for schizophrenia patients?
We’ve talked before about the fact that very large percentage of the fat in your brain is DHA, one of the 2 most important of the Omega 3 essential fatty acids.
In fact there is solid evidence now that having an adequate supply of DHA in the diet, both pre-birth and during infancy, helps with adequate development of the infant brain, helps reduce the likelihood of such conditions as ADHD and can improve our cognition and memory.
Not only that but there is growing evidence that increasing your intake of the Omega 3 essential fatty acids can also help protect against depression.
Interestingly though there is a new report now suggesting that more Omega 3 could also help people with schizophrenia.
That’s a big “could”. That’s because he’s way too early to draw this conclusion.However a new report has suggested that an examination of previous studies could lead to the conclusion that “supplementing the diet with Omega 3 or mega 6 fatty acids may have a positive effect on the symptoms of schizophrenia”.
That’s a long way from saying that more omega 3 either prevent or cures schizophrenia, however it is certainly something for the scientists to continue studying, and if they do, and when they do, we will bring the results to you.
To read the report referenced click hereWritten by - Omega 3 Fish Oil


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Spinnerin Volume 168 ~ Embroidery Stitches Vintage patterns can be beautiful, which is why I bought this old Spinnerin. (front cover) Vintage patterns can also be hilariously tacky, which is why I.
Embroidery Stitches Galore Imaginative Applications / ECI – Crafting Is Joy
Monograms for Linen
Mexican Embroidery, Folk Embroidery, Embroidery Stitches, Embroidery Designs, Natural Linen, Felted Wool, Ottoman, Boho Pillows, Creation Deco

domain: design


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Ipoh Echo’s Eye Health series continues with Consultant Eye Surgeon Dr S.S. Gill talking to us about what needs to be done before you go for cataract surgery.
Arrange time away from work
Patients may need anywhere between a few days to a few weeks off work, depending on the nature of their jobs, before returning to their regular schedule. You should not rush into cataract surgery without sorting this out first as it just adds to your stress.
Arrange for a Driver
It is best to arrange a caregiver to drive you to and from the hospital on the day of your cataract surgery. Make sure your driver is also available on the day after your surgery in order for you to be examined by your doctor on the first postoperative day.
You will need to give a detailed list of all medications that you are currently taking to the eye surgeon as some of these may need to be adjusted prior to the surgery. Never withhold information on any medication or medical problems that you may be having. Accurate information given to your doctor will help avoid complications and quicken recovery after cataract surgery. Unless instructed by your doctor, you will need to take all of your normal medications on the day of surgery.
If you are on medication to thin the blood (antiplatelet medication) your doctor may require you to stop taking them several days prior to cataract surgery. Generally, cataract surgery is bloodless but in some instances adjustments may still need to be made for some of the blood-thinning medication.
If you are a diabetic with poorly controlled blood glucose levels, your physician will be able to help you sort this out prior to undergoing cataract surgery as you will run a higher risk of complications during the recovery process if this is not attended to.
If you are hypertensive, you will still need to take all your antihypertensive medications on the day of surgery. Do not stop taking these medications unless instructed.
If you are on drugs for treatment of enlarged prostate like Flomax and other similar medications known as alpha-blockers, you will need to highlight this to the doctor prior to eye surgery because these drugs may cause eye problems associated with floppy iris syndrome (IFIS) during cataract surgery.
Eating and drinking
Pay special attention to any special instructions regarding meals prior to surgery. Do not drink any alcoholic beverages for 24 hours prior to your surgery. Follow these instructions closely.
On the day of the Cataract Surgery, your face should be free from makeup, eye-liners, cosmetics or powders of any kind. You should also have a thorough hair-wash and shower on the morning of surgery. Wash your face thoroughly with a mild soap. Proper hygiene will also need to be practised during the healing phase after the surgery.
Dr. Gill will discuss more on what happens during surgery in the next issue of the Ipoh Echo.
For more information, contact Gill Eye Specialist Centre at 05-5455582, email: firstname.lastname@example.org or visit www.fatimah.com.my.


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Monday, April 23, 2012
Reeling Backward: "Somewhere in Time" (1980)
Time-travel stories journey through the years themselves, waxing and waning in popularity through different eras. During the 1970s and into the '80s, movies of this ilk were exceedingly popular -- "Time After Time," "Back to the Future," "Time Travelers," etc.
"Somewhere in Time" from 1980 is something different from these other pictures, which play up the science fiction element. Here, the journey back through time is decidedly metaphysical, with Christopher Reeve playing a man who wakes up in 1912 simply because he has willed himself to do so. And he's not tripping through the decades for adventure or scientific conquest, but for Love.
"Somewhere in Time" did not make much of a splash during its initial release, but it's become something of a cult favorite in the intervening years -- even spurring fan clubs, a book and special screenings. It doesn't take much guessing based on the gauzy cinematography, syrupy strings-heavy score by John Barry and starched period costumes to realize that this time-hopping tale is aimed more at the readers of Harlequin Romances than H.G. Wells novels.
I have to confess that I put this flick into my Netflix queue thinking it was actually "Time After Time," a sort of multi-dimensional murder/mystery where Jack the Ripper gets transported to the modern world to ply his gruesome trade. I'm not quite sure if I ever had seen the Christopher Reeve/Jane Seymour romance before, though it's probably not the sort of thing I would have sought out as a preadolescent. If I did watch it, it certainly didn't make a lasting impression.
Watching it recently, I can see why. It's a stiff, stolid affair, with the star-crossed couple existing more as romantic ideals than flesh-and-blood characters. It isn't helped by that tried-and-true cinematic folly, the proposition that two people can fall instantly and irrecoverably in love over the course of a 24-hour period.
The problem with this narrative assertion is that because it's impossible show two individuals intertwining themselves over a period of time, so such a depiction is by definition of telling us that they've found True Love. One of the first rules of writing is to show rather than tell your audience what happens; make them feel it rather than just understand what transpires.
The film is based on a book by Richard Matheson, who also wrote the screenplay, and whose writings often formed the basis for movies: "Real Steel," "The Omega Man," "I Am Legend." I would guess the romantic element was already there, since the whole premise is about a Chicago playwright named Richard Collier who becomes obsessed with the photograph of a stage actress, Elise McKenna. With the aid of an old philosophy professor, Richard resolves that if he dresses himself in period clothing and removes any sign of modernity, he can self-hypnotize himself into slipping backward 68 years.
There's something of a hole in the plot. The story begins in 1972, when a college-age Richard is confronted by an old woman at the premier of his play. She places a beautiful pocket watch in his hands and begs, "Come back to me!" Of course, it is Elise, now ancient and regretful for her long-lost love. Years later, while tooling around the country in the midst of a bout of writer's block, he stumbles upon the Grand Hotel on Mackinac Island in Michigan, sees the photograph and becomes obsessed.
Here's the thing: After he does go back in time and spends that magical day (actually, part of two days) falling in love with Elise, at no point does he ever reveal that he's from the future. Other than taking the easy way out of some potentially complicating matters applying to their courtship, it also means that she had no way of knowing what happened when Richard suddenly disappeared. How did she know to seek out Richard's younger self 68 years later?
That's a paradox, wasted.
The method by which Richard is forcibly returned to 1980 is also rather contrived. While emptying the pockets of his suit, he comes across a penny dated 1979. Confronted by physical evidence of his temporal incongruity, he falls down a dark tunnel of perception and wakes up in modern times.
I realize the exact mechanics of time travel aren't the priority for this movie, but this is just ridiculous. Richard would never be able to completely banish from his mind the knowledge that he's from the future. Just because he encounters a token proving what he already knew shouldn't have any effect on his ability to stay where he is.
Also, if he hypnotized himself into the past once, why couldn't he do it again? After a few hours of failed attempts, Richard instead goes into a state of comatose shock and starves himself to death -- where, of course, he is reunited with his beloved Elise. This strengthens the notion that the entire experience was merely a figment of his imagination.
Christopher Plummer has an interesting role as William Robinson, Elise's over-protective and possibly psychotic manager. He hangs around her Svengali-like, whispering instructions in her ear and putting off an and all interference from outsiders.
In the story, Robinson has warned Elise that a man would someday arrive who would change her life forever -- an indication that he somehow had foreknowledge of Richard's time travel. My understanding is in the book the arrival is presaged by a pair of psychics, but it's left up in the air for the movie. I thought it would have been novel if the filmmakers had suggested that Robinson was another time traveler, himself.
Director Jeannot Szwarc, who's still active today, started out and ended up in television, but not before making some truly awful movies: "Jaws II," "Supergirl," "Santa Claus: The Movie." I regret to say I've seen all of those duds, and wish I could go back in time to get that time back.
1.5 stars out of four

domain: literature


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Suspect who stole package
From Minster Police Department
(11-16-18) On 11/13/2018 (Tuesday) the resident received notification that the phones would be delivered to their home on 11/14/2018 (Wednesday). The incident was caught by a surveillance camera at the residence.
On 11/14/2018 the package was delivered at around 12pm. At around 2:30pm the suspect (pictured above) showed up at the Fort Loramie home (while the residents were at work) and took the package. At approximately 3:30pm on 11/14/2018 Fort Loramie Police were notified of the situation.
If you have any information about this situation or know who this may be contact the Fort Loramie Police Department at (937) 295-4042 OR Shelby County Sheriff’s Office at (937) 498-1111


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News that the Department of Justice has threatened to sue Harvard University if it fails to turn over applicant records, has raised new concerns about the future of affirmative action.
It appears that the Department of Justice is persisting in its Title VI investigation of affirmative action practices at the Ivy League institution.
“The Sessions Justice Department’s investigation into Harvard raises many flags,” said Vanita Gupta, President and CEO of the Leadership Conference on Civil and Human Rights. Previously, she served as the head of the Civil Rights Division at the Department of Justice during the Obama administration.
Gupta said that the Justice Department has typically participated in affirmative action cases only as a “friend of the court” rather than as a direct party. This investigation, she added, indicates a different agenda.
“The attorney general seems to be on the hunt for a case to bring a significant challenge to affirmative action, despite the fact that the Supreme Court has continuously upheld the lawfulness of race conscious admissions in higher education,” Gupta said.
The Justice Department’s investigation is in response to a complaint filed in 2015 by a coalition of Asian-American associations that allege that Asian-American students have been discriminated against by race-based admissions policies.
Over 60 associations jointly filed the complaint using evidence compiled by Students for Fair Admissions, Inc., a nonprofit advocating for race to not be considered in assessing applicants. The complaint alleges that Harvard has illegally used stereotypes and quotas to disadvantage Asian-Americans in the admissions process.
The complaint was dismissed by the Department of Education but remains active at the Civil Rights Division of the Justice Department.
In August, the Division announced that it would begin to investigate race-based admissions practices. Other legal and civil rights experts worry about the possible national impact of such an investigation.
“I’m deeply concerned about what the Justice Department has undertaken here and the potential ripple effect it could have on campuses across the country,” said Kristen Clarke, president and executive director of the Lawyers’ Committee for Civil Rights Under Law, a nonprofit that combats racial discrimination.
She said that the Lawyer’s Committee is currently helping to litigate this matter on behalf of a coalition of students, which includes Asian-Americans.
Clarke described the Department of Justice’s investigation as a “reckless inquiry” that could motivate other universities to take preemptive action in rolling back affirmative action policies to avoid their own federal investigations and lawsuits.
In recently made public letters, Harvard University has responded to the Civil Rights Division with requests for clarifications about the Civil Rights Division’s jurisdiction and rationale for the investigation.
Anurima Bhargava, former chief of the educational opportunities section of the Civil Rights Division at the Justice Department, said that it was unusual that John Gore, acting head of the Civil Rights Division, is writing letters directly to Harvard requesting the documents. According to Bhargava, this would normally be done by trial attorneys rather than by management or political leadership.
In the letters, Harvard’s attorney, Seth Waxman, requested more clarification about the rationale and extent of the investigation. The university expressed a continuing commitment to abide by federal laws as well as to protect its students.
“As we have repeatedly made clear to the Department of Justice, the University will certainly comply with its obligations under Title VI,” said Anna Cowenhoven, a spokesperson for Harvard. “In the process, we have an obligation to protect the confidentiality of student and applicant files and other highly sensitive records, and we have been seeking to engage the Department of Justice in the best means of doing so.”
Joseph Hong can be reached at [email protected]


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Introduction: Blue Heart
This is small gift I made for my girlfriend for Valentine's day. :) Blue is her favorite color. So I decided to make something that is really blue.
First idea was to make copper sulphate crystals (https://www.instructables.com/id/Grow-Crystals/) So i was started making crystals but i failed. :( After two days i only had some small crystals and 2oz of that strange blue liquid you see in picture left...
There was only 2 hours before midnight left, and I decided tomorrow i must gift something to my girlfriend! Then I started thinking and idea shot straight to my head. I grabbed my instructables MagLite and just lighted to bottle with that solution...
This time my failure became succes!
Step 1: Get Stuff
1 - Bottle with cap
3 - Blue leds
1 - 9v Battery
1 - 9v Battery clap
1 - ON/OFF Switch
Enought liquid to fill bottle
Hot glue gun
Dremel or drill
Step 2: Making the Mysterious Liquid
I filled my bottle with copper sulfate solution I made from CuSO4 x 5 H2O salt. You can buy the salt at your local department store. ;)
There is a lot of different colours salts. Ammonium cobalt sulfate is shiny red, potassium dichromate deep red, ammonium dihydrogen phosphate is green. You can find best colours by experimenting.
Well you can paint your liquid, but playing with chemicals is more dangerous and fun.
BY CAREFUL COPPER SULFATE IS HARMFUL!
I added some small shiny tinsel in a solution. They make my liquid more freezing.
Step 3: Make the Cap
Design is very simple just:
1. Prepare your bottle cap.
2. Drill hole and place 3 leds in it.
3. Glue leds with hot glue.
4. Solder your leds and switch.
5. Connect leds with a battery.
There is schematics.
You can add some crystals like i did. ;)
Step 4: Complete Everything
Just make some nice facing. I used copper wire for making a heart and added Myliu Tave "I love you" in my language. :)
Step 5: Overview
Thats it! I made it! :D Small shiny blue night lamp with a heart. :)
Only two hours from idea to finished thing! :) Sure you can make blue bawls concept lamp with light sensitive switch or something much better.
But that is enough for me. :)
However my girlfriend was very happy. ;)
Participated in the
The Instructables Book Contest

domain: chemistry


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Prairie Boy Productions was established in 2013 by multi award-winning bowtie-clad prairie boys Orlando Braun and Jorge Requena Ramos to create high-quality, strong, engaging and insightful stories for Film, TV and other multimedia platforms. These prairie boys are also the only fully fluent Spanish, German, and English film/video production company in Winnipeg, Manitoba, Canada and aim to bring fun stories to bring on social change. Our productions are insightful and aim to alter the status quo and changing the way we see a particular subject. At Prairie Boy Productions, we are driven to make film-making fun again with all our cast and crew, and also for our clients and partners. We produce a range of content from documentary to fiction films, from TV programs to feature films [original productions and service productions] to live events, web content and we even enjoy sprinkling in some short films and music videos! We are the only fully fluent Spanish, German and English production company based in Winnipeg, Manitoba, Canada with access to not only the most talented crew, but the highest tax credits in the country.
A funny, unexpected and insightful documentary exploring humour in Mennonite culture! Comedian Matt Falk digs down into his Mennonite past to discover his heritage is/embraces hilarity and must include more into his comedy act.
Local Rapper and Host Ismaila Alfa discovers urban youth who find their passion & legitimacy in urban arts, including graffiti, rap and hip hop dance!

domain: entertainment


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2 edition of Role of specific antibody, complement, and neutrophils in Tritrichomonas foetus infection found in the catalog.
Role of specific antibody, complement, and neutrophils in Tritrichomonas foetus infection
Mustafa Kemal Aydintug
|Statement||by Mustafa Kemal Aydintug.|
|The Physical Object|
|Pagination||viii, 67 leaves, bound :|
|Number of Pages||67|
Bovine trichomoniasis has many similarities to human trichomoniasis. Both protozoan infections are sexually transmitted and are characterized by clinical signs that vary from asymptomatic to purulent discharge after weeks to months of infection. Since bovine trichomoniasis is a naturally occurring sexually transmitted infection, it can better serve as a model for human trichomoniasis. antibody must be bound to antigen for the conformational change which opens up the C1 binding cite on the Fc portion of the antibody (in the blood steam there is antibody and complement but there is usually never antigen in the blood stream to initiate this conformational change) IgE IgA doesn't fix complement.
Eculizumab is a humanized monoclonal antibody that specifically binds to the human C5 complement protein, prevents its cleavage to C5a and C5b, and therefore prevents formation of the membrane attack complex. 5 Eculizumab is an IgG kappa immunoglobulin with an engineered Fc portion that is a hybrid of IgG2 and IgG4 designed to have no downstream activity—thus eculizumab is a . Firstly, neutrophils can recognize pathogens directly through pattern recognition receptors, or engage them by Fc or complement receptors to opsonized targets. The pathogen is then phagocytosed, where fusion with granules containing anti-microbial molecules and the generation of reactive oxygen species results in its destruction.
When protein is an antibody, the technique is valuable in diagnosing disease. Used commonly to confirm HIV infection. This protein seperation technique (sometimes called the protein immunoblot) is a widely used analytical technique used to detect specific proteins in . Antibody genes also re-organize in a process called class switching, which changes the base of the heavy chain to another. This creates a different isotype of the antibody while retaining the antigen specific variable region, thus allowing a single antibody .
Holding on for heaven
Speeches in plenary session by the Right Hon. W.C. Bridgeman, M.P., First Lord of the Admiralty ...
The mountain is young
White paper on South African land policy
The Martians of Science
Food and Drug Administration, Cincinnati, Ohio.
SIMBIOS PROJECT 1999 ANNUAL REPORT... NASA/TM-1999-209486... MAR. 14, 2000.
The role of bovine antibody and complement in host defense against Tritrichomonas foetus was measured by using an assay of trichomonad viability based complement protozoal uptake of tritiated adenine. Moderate killing was measured in the absence of antibody only with high concentrations of complement-preserved hypogammaglobulinemic bovine by: To illuminate the complex role of neutrophils in infection, inflammation, and immunity, this special issue has gathered original and review articles that will help us Role of specific antibody our knowledge on neutrophil biology.
As stated before, any neutrophil response begins with migration of these leukocytes to the site of infection or by: Immunodiagnosis of Tritrichomonas foetus infection usually involves detection of antigen-antibody reactions with an anti-immunoglobulin conjugate.
The role of bovine antibody and complement in. The complement cascade leading to cleavage of C3 can be activated via three pathways: the classical, lectin, and alternative pathways.
Antibody responses in mice lacking Factor B of the alternative pathway (Matsumoto et al.,Mehlhop and Diamond, ) are lacking mannose-binding lectin (MBL) of the lectin pathway have either normal, moderately higher or.
Protection by surface antigen TF of Tritrichomonas foetus was investigated because it reacted with a monoclonal antibody which immobilized and mediated complement killing of the organism and.
findings demonstrate antibody enhancement of complement-mediated killing of T. foetus by the alternative pathway ofbovine complement. Tritrichomonas foetus, a venereal pathogen of cattle, causes infertility, abortion, and pyometritis and results in economicloss to the cattle industry in the United States and worldwide (1, 6, 9, 12, 21, 28).Cited by: Neutrophils and the complement alternative pathway (AP) are major effectors of cell-mediated and humoral innate immunity.
The analysis of complement knockout mice, in experimental inflammatory diseases, shed new light on the participation of complement AP in neutrophil-mediated diseases, such as rheumatoid arthritis, 1 membranoproliferative glomerulonephritis, 2 ischemia.
Complement was discovered by Jules Bordet as a heat-labile component of normal plasma that causes the opsonisation and killing of bacteria. The complement system refers to a series of >20 proteins, circulating in the blood and tissue fluids.
Most of the proteins are normally inactive, but in response to the recognition of molecular components of microorganisms they become. Neutrophilic granulocytes or polymorphonuclear neutrophils (PMNs) are the most abundant white blood cell in humans and mice.
They are characterised by the multi-lobed shape of their nucleus (Figure 1, left) which distinguished them from other white blood cells of.
Complement receptors are heterogeneous receptors expressed by APCs (Figure ) that mediate direct and lectin- and antibody-dependent binding of activated complement components and play a role in cell migration and phagocytosis and immune regulation. 65 The discovery of a novel complement receptor selectively expressed by Kupffer cells.
Antibodies can also induce the innate immune response to destroy a pathogen, by activating phagocytes such as macrophages or neutrophils, which are attracted to antibody-bound cells. Affinity describes how strongly a single antibody binds a given antigen, while avidity describes the binding of a multimeric antibody to multiple antigens.
The antibody response and the complement system are major effector arms of the immune system. Both have been involved in a plethora of pathological conditions—including autoimmunity, allergy, infections and cancer—and regulate, mainly through their receptors (FcR and CR respectively) cell activation, migration, survival but also metabolism.
The major role of the complement system is to work in conjunction with A. antibodies to lyse cells via the C8 and C9 components B.
antibodies to lyse cells via the perforin molecules. The complement system is part of the innate immune system and plays an important role in the host defense, inflammation, tissue regeneration and other physiological processes. Complement activation results in opsonization of pathogens and their removal by phagocytes.
It also causes chemotactic attraction of phagocytes and macrophages. The complement system is an evolutionarily well-conserved system of which the current complexity in jawed vertebrates emerged million years ago, while some components of the most primitive complement system date billion years back (Nonaka and Kimura, ).Complement was identified in the late s as a heat-labile, bactericidal component in serum (Bordet,Ehrlich.
Fig 1. The classical complement pathway. As shown in fig 1. the classical pathway can be initiated in two ways. C1q (part of the C1 complex), either binds to the pathogen surface directly, or binds to the Fc region of an antibody:antigen complex during the adaptive immune response. antibody [an´tĭ-bod″e] an immunoglobulin molecule having a specific amino acid sequence that gives each antibody the ability to adhere to and interact only with the antigen that induced its synthesis.
This antigen-specific property of the antibody is the basis of the antigen-antibody reaction that is essential to an immune response.
The antigen. In naturally infected cats, similar to human T. vaginalis and bovine T. foetus infection, feline T. foetus infection histologically is characterized by an influx of lymphocytes, plasma cells and neutrophils into the subepithelial lamina propria (Fig 6).
38 The proinflammatory molecules responsible for eliciting intestinal inflammation in T. Antibody to H antigen is infrequently detected (infection. The M antigen has also been cloned and sequenced, and it has a high degree of homology to catalase. Unlike the H antigen, antibody to M antigen is detected in up to 80% of individuals following exposure to the fungus.
The complement system is part of the innate immune system, eliciting central immunoregulatory functions. Detection of foreign surfaces is either achieved through complement-specific patternrecognition molecules or mediated by antigen recognition of antibodies.
Immunoglobulin A (IgA), IgG, and IgM all have the potential to initiate a complement response, with the efficiency and. Background The neutrophil population makes up the largest proportion (40–70%) of white blood cells and is crucial to our innate immune response.
An unexpectedly significant proportion of neutrophils (∼28%) is located in the pulmonary circulation. This is an immune system front line wherein neutrophils guard an important interface between the external environment and the body.Complement components have other immune functions that are mediated by complement receptors (CR) on various cells.
CR1 (CD35) promotes phagocytosis and helps clear immune complexes. CR2 (CD21) regulates antibody production by B cells and is the Epstein-Barr virus receptor.
Scientists have engineered an antibody that attacks 99% of HIV strains and can prevent infection in primates. This new Trispecific antibody is built to attack three critical parts of the virus.