Birmingham News/January 8, 1923
NEW YORK, Jan. 8.—Jack Dempsey buys an apartment house in Los Angeles for $250,000 as an investment.
He already owns a home in Los Angeles that cost him over $100,000. He has property in Salt Lake City.
Dempsey is 27 years old. Seven years ago he was a hobo “mooching”—as hoboes describe begging at back doors for something to eat.
Henry Peace, “the game chicken,” who held the same title that Dempsey holds now, died April 30, 1809, at the Coach and Horses, St. Martin’s Lane, London, 32 years old, broke, down and out.
Dempsey has saved his money—no doubt of that, when he can make investments representing a quarter of a million dollars.
It may be accepted by some as a sad commentary on a civilization that permits a man to make this much money at prize fighting.
But Dempsey must also be accepted as a lesson in conservation of earnings as against “The Game Chicken” and his times.
“Why should I be subject as others are subject to the pitiful law called age?” cried Casanova.
He was then 55.
Jess Willard is not that old. He is perhaps not more than 40. The New York state boxing commission says 40 is too old for a man to engage in ring fighting.
The commission is right. Forty is old age in the pugilistic game. At 40 a man cannot stand the strain of training, cannot get in physical condition to combat rugged eager youth.
Willard is coming to New York to attempt to arrange a match with Dempsey. He is waiting his time. The rules of the boxing commission and the “pitiful law called age” definitely operate against Willard, the last more than the first.
Baseball magnates fought one war, the first in nearly a quarter of a century, a few years ago. This was the Federal League war.
The magnates found it most expensive. They are still paying for it. One man who thought he had enough money to last him the rest of his life was ruined.
The baseball fans need not worry for another 25 years over quarrels among the baseball magnates. The magnates have found compromise less costly than war. Nations have recently discovered the same thing.
As among nations, however, it seems to require a war at certain intervals to teach the lesson to baseball magnates all over again.


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Wagakki Band Reveal MV for “Valkyrie – Ikusa Shojo”, Theme Song for Sousei no Onmyouji Anime!
Wagakki Band have raised the curtain on the “TV-sized” MV for “Valkyrie – Ikusa Shojo” from their split single with Hitomi Kaji “Valkyrie – Ikusa Shojo/Eyes” (release date: June 24)!
“Valkyrie – Ikusa Shojo” is the opening theme song for the anime Sousei no Onmyouji (Twin Star Exorcists) and puts Wagakki Band in warehouse surrounded by corrugated metal and beams of light.
Here is Hitomi Kaji’s MV for “Eyes”, which is the ending theme song for Sousei no Onmyouji (Twin Star Exorcists).
“Valkyrie – Ikusa Shojo/Eyes” will be sold in a CD/DVD version and a CD version. The CD/DVD version includes anime (full length) and Wagakki Band/Hitomi Kaji (TV size) MVs as well as a roundtable discussion with Wagakki Band, Hitomi Kaji, and the seiyuu from the series.
Wagakki Band also released a trailer for their 1st US Tour Shougeki -DEEP IMPACT- which will take them to Los Angeles, San Diego, and San Francisco.
Let’s hope it’s just the beginning of bigger and more extensive international tours to come!
Wagakki Band Official site: http://wagakkiband.jp/
Wagakki Band Official Twitter: https://twitter.com/wagakkiband
Wagakki Band Official Facebook page: https://www.facebook.com/WagakkiBand
Wagakki Band Official Instagram: https://www.instagram.com/wagakkiband/
Hitomi Kaji Official site: http://avex.jp/kajihitomi/
Hitomi Kaji Official Twitter: https://twitter.com/kaji2608
Sousei no Onmyouji Official site: http://sousei-anime.jp/
Bandjanaimon! Prepare for Their Bright Future in the MV for “Kimochi Dake Sanka Shimasu.”
Risa Satosaki Reveals Everything in the MV for “S!NG”!

domain: artistic


The Austin City Council reviewed revisions to the Rec Center lease agreement with Austin YMCA manager Diane Baker at a work session following their regularly scheduled meeting Monday evening at Austin City Hall.
Baker stated to the council that the YMCA at the Austin Community Recreation Center was requesting two revisions to the original lease agreement with the city, one being the youth activity center being available for students in grades 2-12 instead of 5-12, and the other concerning the payment of $100,000 per year by the YMCA at the Austin Community Rec Center to the city. Baker stated that given budget projections for year one, the YMCA will not have a positive cash flow. She went on to state that in order for them to manage expenses, they were requesting that the payment of $100,000 be dispersed on a quarterly basis starting in March of 2020. The council moved unanimously to approve the revisions to the lease, and Baker added that the Rec Center is scheduled to open on February 3rd.
In other business, the Austin City Council reviewed a wastewater treatment plant flood mitigation study with Public Work Director Steven Lang, who stated that the council approved a contract with SEH in November of 2018 for a study to evaluate flood mitigation options for protection of the facility. Lang stated that the facility is protected by a levee system that was built primarily under emergency conditions to protect against rising floodwaters of the Cedar River. He went on to state that due to the nature of the construction and lack of design for the existing system, it is highly unlikely that the existing system will meet the minimum FEMA requirements for accreditation without significant modifications or reconstruction. Lang stated to the council that the goal of the design study was to develop a feasible flood mitigation system that protects the wastewater treatment plant and can be built to meet the minimum requirements for FEMA accreditation without reducing the level of protection afforded by the existing system during construction.
Lang presented the council with three alternatives for their consideration and recommended the third option, which was the most cost effective at $8,205,000. Lang stated to the council that assuming funding is in place, construction of the entire project could likely be completed in one construction season, with design and permitting in 2020 to 2021 and construction in 2022.


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Cassidy Travel Nominated in the Republic of Ireland Category for the 2023 Travel Weekly Agent Achievement Awards!
Cassidy Travel, Ireland’s leading independent and multi-award-winning travel agent, has done it again, being nominated and making the shortlists in the Republic of Ireland category for the 2023 Travel Weekly Agent Achievement Awards! Cassidy Travel previously won this award for Irish travel agency of the year in 2019, 2021 and 2022.
“We are delighted to be once again shortlisted for this award!” said Sharon Harney, General Manager of Cassidy Travel “It is a testament to the commitment and dedication of our amazing staff who work so hard every day to keep our clients happy.”
The Travel Weekly Agent Achievement Awards are the largest celebration of the travel trade in the Ireland & UK and the highest accolade for travel agencies and agents. The awards are designed to honour those travel agencies and travel agents who truly represent the best of the travel industry and recognise excellence in a range of categories and specialisms. The shortlists include agencies nominated by more than 100 suppliers, ranging from tour operators and cruise lines to airlines, tourist boards, agents and ancillary companies.
Nominated and self-nominated categories also feature individuals from a wide range of companies and business models in addition to up-and-coming start-ups and those who have demonstrated outstanding commitment to sustainability and staff wellbeing and development. Winners will be announced at a glittering awards ceremony at the Westminster Park Plaza Hotel in London on Thursday, July 13th. Best of luck to all at Cassidy Travel!

domain: geography


Are you considering installing an NVMe SSD in your old desktop? The process is actually pretty simple and only takes a few minutes. Here’s a step-by-step guide on how to do it:
First, you’ll need to purchase an NVMe SSD that is compatible with your motherboard. Make sure to check the compatibility before making your purchase. Once you have the SSD, locate the M.2 slot on your motherboard.
It’s usually located near the CPU socket.
- Check your computer’s BIOS to see if it supports NVMe SSDs
- If it doesn’t, you’ll need to update the BIOS in order to use an NVMe SSD
- Connect the NVMe SSD to your computer using a compatible cable or adapter
- Format the NVMe SSD using a compatible file system for your operating system (e
- , NTFS for Windows or HFS+ for macOS)
- Install your operating system on the NVMe SSD if you haven’t already done so
- Configure your operating system to boot from the NVMe SSD if necessary (this may be automatic)
- That’s it! Your computer should now be able to take advantage of the faster speeds offered by an NVMe SSD
Can I Install Nvme Ssd on Old Pc?
Yes, you can install an NVMe SSD on an old PC. You’ll need to make sure your motherboard supports NVMe and that you have a compatible slot for the SSD. Most newer motherboards should support NVMe, but you’ll want to check your manual or manufacturers website to be sure.
If your motherboard does not have a dedicated NVMe slot, you can use an adapter card.
How Do I Install Nvme on My Desktop?
If you’re looking to install NVMe on your desktop, there are a few things you’ll need to do first. For starters, check to see if your motherboard is compatible with NVMe – most newer boards should be, but it’s always best to check beforehand. If it is, then the next step is to make sure you have the correct drivers installed.
Again, most newer versions of Windows should have these automatically installed, but it’s worth checking for updates just in case. Once that’s all squared away, the actual installation process is pretty straightforward. Just pop in the NVMe drive into an available PCIe slot and boot up your computer – everything else should take care of itself.
If you run into any issues or questions along the way, don’t hesitate to reach out to us and we’ll be happy to help!
Can I Use Nvme Ssd in My Old Laptop?
If you have an older laptop, you might be wondering if you can use an NVMe SSD in it. The answer is yes, but there are a few things to keep in mind.
First, your laptop will need to have a PCIe slot.
Most laptops made in the last few years will have at least one PCIe slot, but if yours is particularly old it might not. If your laptop doesn’t have a PCIe slot, then unfortunately you won’t be able to use an NVMe SSD in it. Second, even if your laptop does have a PCIe slot, it might not be compatible with NVMe drives.
This is because NVMe drives use a different connector than traditional SATA drives. So, even if your laptop has a PCIe slot, make sure to check that it’s compatible with NVMe before buying an SSD. Finally, even if your laptop has a compatible PCIe slot and is capable of using NVMe drives, there’s no guarantee that every game or application will work properly when installed on an NVMe drive.
So while you can technically use an NVMe SSD in an older laptop, there are some potential compatibility issues to be aware of.
Can I Use Nvme Ssd in Hdd Slot?
Yes, you can use an NVMe SSD in a HDD slot with the help of an adapter. This is because the physical dimensions of an NVMe SSD are smaller than a traditional HDD. The main benefit of using an NVMe SSD in a HDD slot is increased speed and performance.
Additionally, you won’t have to worry about compatibility issues since most adapters are designed to be compatible with both types of drives.
🔧 How to install an NVMe SSD in an old desktop PC with a PCIe slot adaptor
Installing Nvme Ssd on Older Motherboard
As the price of NVMe SSDs continues to drop, more and more people are looking to upgrade their older motherboards to take advantage of the faster speeds. While it’s not a difficult process, there are a few things you need to be aware of before you get started.
The first thing you need to do is check your motherboard’s compatibility list to see if it includes an NVMe slot.
If it does, great! If not, you’ll need to purchase a separate NVMe controller card. Once you’ve confirmed that your motherboard is compatible, the next step is to physically install the drive.
Most NVMe SSDs come with their own bracket that needs to be mounted onto the motherboard. Once that’s in place, simply insert the drive into the slot and secure it with screws.
This will ensure that your system recognizes the new drive and allows you to boot from it. Consult your motherboard’s manual for specific instructions on how to do this. And that’s it!
After following these simple steps, you’ll be up and running on a faster NVMe SSD in no time.
How to Install Nvme Ssd Without M 2 Slot
If you’re looking to upgrade your PC with a new NVMe SSD, but don’t have an M.2 slot on your motherboard, don’t despair! In this guide, we’ll show you how to install an NVMe SSD in a standard PCIe slot.
The first thing you’ll need is a compatible SSD.
Not all NVMe SSDs will work with this method, so be sure to check compatibility before making your purchase. Once you’ve got your hands on a compatible drive, the next step is to physically install it into your computer. If your case has an available 3.5″ bay, then installation is as simple as mounting the drive in the bay and connecting it to one of your system’s SATA ports.
If not, then things are a bit more complicated – but still doable! To install in a 5.25″ bay, or directly into the PCIe slot itself (which is what we’ll be doing), you’ll need to use a special adapter bracket that converts the SSD’s M.2 connector into something that can connect to either type of port/slot. These brackets are readily available online from various retailers for around $10-$20 USD.
With the bracket in hand, installation is simply a matter of screwing it onto the drive and connecting it to whichever type of port/slot you’re using (iPCIe or SATA). Once everything is connected up and screwed down tight, boot up your PC and enter its BIOS/UEFI settings menu. From here, find the section dedicated to storage configuration and ensure that both AHCI mode and hot-plugging are enabled for any SATA ports being used by the NVMe SSD (including any optical drives also attached to those ports).
Save these changes and exit BIOS/UEFI; upon reboot Windows should now detect and properly initialize the drive without issue!
How to Install M.2 Ssd in Old Laptop
If your old laptop is still running strong but could use a little speed boost, installing an M.2 SSD is a great way to give it new life. M.2
SSDs are much faster than traditional hard drives and can really breathe new life into an aging machine. Installing an M.2 SSD is not as difficult as you might think.
In fact, in many cases it’s actually easier than upgrading to a new hard drive because you don’t have to deal with any cables or mounting brackets. The first thing you need to do is purchase an M.2 SSD that is compatible with your laptop.
Make sure to get the correct size and interface for your machine – most laptops use SATA-based M.2 SSDs, but there are also PCIe-based drives available for some models (typically higher-end gaming laptops). Once you have the proper drive, simply insert it into the slot on your laptop’s motherboard and secure it with any screws that may be required (this will vary depending on your make and model).
Now that the hardware is installed, you’ll need to install the appropriate drivers for your new SSD before Windows will recognize it. This should be included on a disc that comes with the drive, or you can download them from the manufacturer’s website. Once everything is set up and ready to go, simply boot up your computer like normal and enjoy the blazing fast speed of your new solid state drive!
Nvme Adapter for Desktop
NVMe adapters are becoming more and more popular as the preferred way to connect NVMe SSDs to desktop PCs. Here’s everything you need to know about NVMe adapters, including what they are, why they’re better than other connection methods, and which ones to buy.
What is an NVMe Adapter?
An NVMe adapter is a device that allows you to connect an NVMe SSD to your desktop PC. NVMe adapters come in different form factors, including PCI Express (PCIe) cards, M.2 cards, and even USB devices. They allow you to take advantage of the high speed and low latency of NVMe SSDs without having to replace your existing storage devices or upgrade your motherboard.
Why Use an NVMe Adapter? There are several reasons why you might want to use an NVME adapter with your desktop PC. First, if you have an older motherboard that doesn’t support theNVMe protocol, using an adapter will allow you to still use those newer drives.
Second, even if your motherboard does support NVME drives, using an adapter can sometimes offer better performance than connecting the drive directly to the motherboard. And finally, if you’re looking for a way to connect multipleNVMe drivesto your PC (for example, if you’re building a RAID array), then using an adapter with multiple slots may be the best option. WhichNVMEAdapter Should You Buy?
when it comes time important consideration is compatibility both with your operating system and with the specific slot on your computer into which it will be inserted . Other considerations include price , speed , features , and brand .
If you have an older desktop and want to install a new Nvme SSD, there are a few things you need to know. First, check your motherboard to see if it has an M.2 slot. If it does, then you can simply install the SSD into that slot.
If not, then you’ll need to use a SATA to USB adapter. Once you have the proper adapter, installing the SSD is relatively easy. Just connect it to the SATA port on your motherboard and boot up your computer.
You may need to go into your BIOS and change the boot order so that your computer boots from the SSD first. And that’s it! Now you can enjoy faster boot times and data transfer speeds with your new Nvme SSD.


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Food is a central part of the Filipino life. Food and agriculture is central to rural development, a source of livelihood of small farmers, and a reflection of Filipino’s ingenuity and resilience. For the people of an agricultural country such as the Philippines to go hungry due to increased control of industrial agriculture giants, is therefore unacceptable and must be resisted.
This was the central theme of “Food. Farming. Freedom.: Breaking Food Chains, Building Food Webs,” a gathering of more than 100 local producers and consumers advocating for food access and justice held in Ateneo De Manila University on October 26. The event aimed to “raise greater awareness of the critical issues surrounding the current food system, skewed towards corporatization and profit-centricity” and promote a healthier, safer, more just and sustainable alternative food production systems. Farmer-scientist group MASIPAG is among the organizers of Food. Farming. Freedom, along with Good Food Community, Me & My Veg Mouth and Bread of Freedom.
“This is a timely activity as we get to further expose the state of our food system and why we experience rice and food crises,” said Cris Panerio, National Coordinator of farmer-scientist group MASIPAG. “Food systems are not only about how we grow our food, and how the consumption and distribution of food affects the environment or contributes to climate change. It also about who controls and dominates the kind of production and resources we use and access.”
Privately-owned and profit-driven technologies such as patented high-yielding and genetically modified seeds are being prominently promoted by governments to supposedly improve and develop food production. The use of these expensive seeds and other external inputs such as synthetic fertilizers and pesticides has changed not only the agricultural production, but also the consumption and buying patterns of Filipinos.
The event featured a variety of interconnected inputs from resource persons, and workshops that aim to encourage actions and alternatives from the farmers, consumers, and other sectors who participated. Farmers also brought organic products and shared seeds among participants, while chefs prepared dishes out of the produce from farmers.
Chef and educator Asha Peri of Bread of Freedom discussed the industrial food chain and peasant food web to show that local food security is possible through the production and consumption of local food crops. “By supporting our own food webs, we are assured of our health and safety, as well as the safety of our planet.” Peri later went on to lead a workshop on “how to provide plant-centered education in pre-schools.”
“It is important that we re-shape how we see and treat traditional and local foods, and it can be done by starting with the little kids and instilling with them the value of eating right and healthy.”
The Food. Farming. Freedom event likewise touched on the issues currently faced by the agriculture sector. The Rice Liberalization Law and the genetically modified Golden Rice were also discussed extensively, eliciting broader support from ordinary consumers.
“On one hand, the rice crisis that our farmers are experiencing right now has generated awareness and support from the Filipino public,” said Panerio. “We hope that this support can be sustained and translated into positive action that will address the farmers’ issues and in the longer term, assert for better policies in food production.”
“We encourage the people to support the calls such as the junking of the Rice Tariffication Law, and the halt of the Golden Rice commercialization.”#

domain: agronomy


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Blogs. I'm sorry to be anticlimactic, but that's all there is to it. It was released in Japan in … Want to share IMDb's rating on your own site? When Ash, Pikachu, and their friends visit a desert city by the sea, they meet the Mythical Pokémon Hoopa, who has the ability to summon things-including people and Pokémon-through its ... See full summary ». 597,028 views. Einloggen Noch keinen Account? you ask. Comments on Movie: The Mastermind of Mirage Pokémon (2006) "An exciting and action … Level 95. (TV Movie 2006). With James Carter Cathcart, Michele Knotz, Rodger Parsons, Bill Rogers. The story of "The Mastermind of Mirage Pokémon" centers on a Pokémon scientist who has developed a new Mirage System to resurrect extinct Pokémon. However, a masked villain, the 'Mirage Master', takes control of the device to use it for his own sinister goals. An over zealous pokemon called Keldeo enrages a very powerful Kyurem, with the help of Ash and Pikachu can Keldeo become a sword of justice and defeat the mighty Kyurem? Pokemon - Das Superhirn der Miragepokemon (The Mastermind of Mirage Pokémon) Bewertung: 7,0 / 10,0 (1 Stimmen) Ash erhält Post von Dr. Yung. More from this season. (Lucario and the Mystery of Mew Bonus Disk) Come chat with us here! When Pikachu is taken to the Tree of Beginnings by the playful Mew, Ash Ketchum and friends are guided to the tree by Lucario, a time-displaced Pokémon who seeks answers regarding the betrayal of his master. The Mastermind of Mirage Pokémon (戦慄のミラージュポケモン, Senritsu no Mirāju Pokemon?, lit. The Mastermind of Mirage Pokémon(戦慄のミラージュポケモンThe Terrifying Mirage Pokémon) (though officially English-titled Pokémon: The Mastermind of Mirage Pokémon in the title card left in for the Japanese version) is a special episode that was released as a 10th anniversary theme which originally aired in the United States. Pokémon Special 11 - Iris vs Ibuki! Satoshi, Haruka, Masato, and Takeshi show up at the Mirage Mansion for a demonstration of this new machine, only to witness the kidnapping of the scientist! Home; 2018; Friday, 15 February 2019. Buy Movies. Citron and Dent!! WATCH NOW. Comments on Movie: The Mastermind of Mirage Pokémon (2006) "An exciting and action packed movie with excitement and drama." The story of “The Mastermind of Mirage Pokémon” centers on a Pokémon scientist who has developed a new Mirage System to resurrect extinct Pokémon. To which I respond: "Mewtwo Returns." Some have suggested it would have worked better as a double episode, but even then it would have been a disgrace. … Cosmo (Eevee (KS)) Level 12 Joined: May 25, 2014 Posts: 4,535 PokéPoints: ₽649.3. Theme Design by PsyThemes / PsyPlay 1.2.5. As of writing, "Pokémon: Castle in the Sea" (as I remain it should be called) is still the longest film in the franchise at a not entirely justified 1h45m, and I must admit I was looking forward to "The Mastermind of Mirage Pokémon" as a short intermezzo. 02 - The Mastermind of Mirage Pokémon. Ash and company meet Mr. Giovanni for the first time. In my ongoing quest to destroy my childhood I have set out to (re)watch all Pokémon films, and see how they hold up now that I am an adult. Pokémon Special 11 - Iris vs Ibuki! The definitive site for Reviews, Trailers, Showtimes, and Tickets Directed by Masamitsu Hidaka. Team Rocket's memories of Mewtwo had been erased, but the Team Rocket scientists' logs have not. Add the first question. Super Reviewer. Ash is receiving a letter from Dr. Yung, inviting him to his laboratory to show him his new creation: Mirage-Pokémon, which are supposedly much more powerful than "normal" Pokémon. It became available on DVD in the United States on September 19 that year as a special feature on the 2-disc Pokémon: Lucario and the … It is awful.The story is incited the same way as the first film's: with Ash being invited by an enigmatic challenger. Trailer. What to Watch Latest Trailers IMDb TV IMDb Originals IMDb Picks IMDb Podcasts. If you are not amongst the biggest of Pokémon fans or working on a silly retrospective like me, there is no reason to watch it at all. Super Reviewer . Pokémon: The Mastermind of Mirage Pokémon (Japanese: 戦慄のミラージュポケモン The Terrifying Mirage Pokémon, officially Mastermind of Mirage Pokémon in Japan) is a special episode of the Pokémon anime. Japanese title: 戦慄のミラージュポケモン (Senritsu no Mirāju Pokemon) Other title: Het Meesterbrein van de Illusie-Pokémon, Mirage-Pokémonien herra, Le maitre des mirages, O Mentor do Pokémon Miragem, 전율의 미라주 포켓몬. Animation. Citron and Dent!! At the end of the TV series of the same name, it is revealed that the husband works for the Public Security Bureau, and their marriage is a cover to…, The Black Mask Organization coordinates a twisted plot which will devastate the world within the next 36 hours. Dr. Yung appears and challenges both Misty and Ash to a battle. The Mastermind of Mirage Pokémon WATCH NOW. The new cast is inferior to the previous in all respects, and although they managed to do a serviceable job in some of the later Pokémon films, here they sound absolutely terrible - as if the translators' neigbhours were invited over to give it a shot.I would recommend watching the dub nonetheless. Tags: pokemon movies; Cadbberry. 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domain: entertainment


On May 1, 2006, Governor Rendell signed Act 31 which enacted a new Section 1614 of the School Code to permit participation in High School graduation ceremonies by non-graduating disabled students. The new law is to take effect immediately and School Districts should take steps to implement the law for graduation ceremonies in 2006 and into the future.
The new Section 1614 recognizes that there are students with disabilities whose IEP provides for continued special education programs beyond the fourth year of High School. That Section provides that as long as the student has attended four years of High School, regardless of whether they have completed the IEP program, they may still participate in graduation ceremonies with the student’s graduating class and receive a Certificate of Attendance. The change in the law does not prevent a student with a disability from receiving a High School Diploma when the student satisfactorily completes his or her IEP, nor does it require a student to participate in graduation ceremonies based solely on four years of High School attendance. The General Assembly’s discussion of Act 31 recognized that “the opportunity for classmates with disabilities to celebrate their accomplishments together occurs only once, and the opportunity to celebrate the receipt of a diploma several years after one’s classmates have graduated diminishes the experience for students whose age peers have left high school several years earlier.”
IEP teams should consider whether a student has attended four years of high school and is therefore entitled, if the student so desires, to participate in graduation ceremonies.


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Due to the increasing demand in Eastern Europe area, Magna Tyres has announced the opening of another sales office in Czech Republic. Leaded by Mr. Danil Špaček, the new office also serves to be closer to the Slovakian market.
“We took a great deal of care in choosing this location for our new office. This strategic decision enables Magna Tyres to further strengthen our commitment, enhance the efficiency, to provide better services, expand our scope, and enable new projects. This regional office will strengthen our footprint and offer a dedicated local business professional for our clients and partners,” said Marcin Kochaniak, Managing Director Magna Tyres Poland.
He added: “We are confident Mr. Špaček possesses the kind of substantive expertise, leadership strength and business acumen that will help guide Magna Tyres as we continue to grow and strengthen our position as a global leading 2nd tier tyre brand in the tyre industry” accordingly Marcin Kochaniak, Managing Director Magna Tyres Poland.

domain: economics


6852QED's latest 2: EMOREJ and CHROMER
- May 1 1:50 AMdownload the two latest releases on QED RECORDS:
+ + +
Once again, the samplist known as Emorej pits his Acid
Pro skills against vocal loops, 4-on-the-floor
kickdrums and all sorts of fine funky riffs to come up
with an album that is equal parts Dance Dance
Revolution, Moby, C+C Music Factory and Towa Tei. This
is one Potpourri that sure smells funky as a llama's
ass. 13 tracks!
EP: IKAW MAGANDA
Sullen minimalist downtempo tunes flavored with a
little IDM/glitch put together by a
classically-trained electronica composer who takes
inspiration from the Philippines and transforms it
into audio snapshots of decay and beauty. The standout
is the all-too-brief "Paradise Island" which pits lush
soundtrack strings with ambient jungle sounds. Ikaw
Maganda (which literally means "you beautiful" in
Filipino) is Chromer's first QED release, but
definitely not his last.
~ lionel valdellon ~
::ABOUT QED RECORDS::
QED Records is a non profit netlabel based in the
Philippines, offering the best independent electronica
created by Filipinos, for free download.
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Tired of spam? Yahoo! Mail has the best spam protection around


text:
The Organic Food Shopper's GuideWhy Should You Choose Organic Foods?Organic food has never been more popular, and for good reason: it tastes better, it's more nutritious, and it's better for the environment. This handy guide shows you how to select the freshest, tastiest varieties and transform your organic groceries into memorable meals. You'll find guidance on what to look for when shopping, how to handle each food in the kitchen, and why, when foods are organic, they're so darn good for you. Here's everything youneed to enjoy food that you can feel great about eating:* Profiles of more ...
This inspiring cookbook answers the call for healthy recipes for family-friendly organic meals -- snacks, breakfasts, lunches, dinners, desserts, and extras. Sidebars and tips throughout promote green living -- organic child- and family-specific gardening ideas and inspiration for community building and sustainable living. Recipes use easily obtainable ingredients from standard grocers, green markets, or the small family garden plot. Recipes are both wholesome and kid- and family-tested approved! Bonus recipes for favorite, everyday basics and delicious, seasonal treats. Tips and anecdotes throughout the book offer simple gardening, green living, and community-building ideas.
Avocado oil is most comparable to olive oil; however, direct replacement is not advised in all circumstances. Swanson Certified Organic Avocado Oil is cold pressed not from the seed but from the fleshy fruit of the avocado itself.

domain: hobby


text:
“If Zaha is in Paris, ask her to text me and make an appointment.” So read the text message from Karl Lagerfeld to Naomi Campbell. La Campbell was having a sit-down with Zaha Hadid, who happens to be designing the supermodel’s new house outside Moscow. But this wasn’t a meeting to review floor plans—it was an on-the-record chat (including incoming texts) for the German edition of Interview magazine. The conversation ranged from the subject of Hadid’s new book (on the Russian Suprematist movement, one of her foundational influences) to 3-D printers.
Funnily enough, Campbell covers a lot more ground than architecture writer Aaron Betsky manages in his recent and rather fluffy profile of Hadid for Glamour magazine, which named the architect as one of its Women of the Year. Here, Betsky cites Mame rather than Malevich as an early influence: “My house was like Auntie Mame’s, with my mother redecorating every season,” said Hadid.
In a recent issue of The New Yorker, writer Ben McGrath profiles Steve Clarkson, the private football coach to the quarterbacks of tomorrow. The writer interviews several adolescent clients attending Clarkson’s elite practice camp, including 10-year old Miller Moss (also featured on the article’s only photo). During a workout McGrath finds Moss’ father in the stands—California-based architect Eric Owen Moss.
“I would be completely disingenuous if I didn’t say I really enjoy this stuff,” said the elder Moss of the high-stakes training. “I’m embarrassed a little bit. It’s contagious in a way that even parents who should know better don’t always.” The design influence of the architect—once called the “jeweler of junk” by Philip Johnson—may be evident on the field: his son sports silver Nike cleats with the nickname “Miller Time” embroidered in gold.
On October 16 thieves nabbed a handful of valuable paintings, including works by Picasso, Matisse, and Monet, from the Kunsthal gallery in Rotterdam. At least one person points the finger at the architecture by home team OMA. Citing an interview with Dutch security expert Ton Cremers, Dezeen.com reports that the open plan and glass walls are a nightmare for guards. Cremers appreciates the design aesthetic of the museum, which was completed in 1992, but noted, “It’s an awful building to protect.”
AN has been anxiously awaiting official news of an architect for Los Angeles’ long-awaited Downtown Federal Courthouse, and we’ve picked up the scent of a promising rumor. Brigham Young’s DTLA Rising blog has heard from a “source at a large architectural and design firm in Downtown LA” that SOM has won the commission, beating out a short list of teams including Yazdani Studio and Gruen Associates, Brooks + Scarpa and HMC Architects, and NBBJ Architects.
The new $322 million courthouse will be located on a 3.7-acre lot in Downtown LA at 107 South Broadway and will contain 600,000 square feet incuding 24 court rooms. The General Services Administration (GSA), the federal agency in charge of building the new courthouse, hopes to have the project completed by 2016. The former art-deco courthouse at 312 North Spring Street will be sold to help pay for the new structure, drawing criticism from some politicians.
The GSA is expected to make an official announcement soon, and we’ll be sure to keep you updated as news comes in.
In a letter to Building Design magazine, the Architects Registration Board in London, aka ARB, has requested that BD no longer refer to Renzo Piano and Daniel Libeskind as “architects.” Apparently, neither are registered as architects with the all-knowing ARB, therefore “they are not entitled to be described as such,” states the letter. BD Editor-in-Chief Amanda Baillieu immediately called out ARB’s high-handed mandate in an online editorial, writing, “there is no other word to describe ARB’s ban on calling Renzo Piano an architect except bonkers.” The registration board’s Alison Carr later apologized for the letter, “Do I think that this was a great example to bring to BD’s attention and help raise awareness? No I don’t. We should have been more cautious so that we get the right message across at the right time, and for that I apologise.”
Everybody seems to be opening up new offices these days. One of our favorite firms, Barton Myers Associates, is moving from Westwood all the way to Santa Barbara, which doesn’t sound promising. Cunningham Group has opened new digs in Culver City’s Hayden Tract, the collection of arts offices made famous by the wild constructs of Eric Owen Moss. And UCLA Architecture will remain in Westwood. But it’s ready to open a new robotics lab inside the old Playa Vista research facilities of Howard Hughes.
You can’t make a monument without breaking some eggs. Fabergé cosmetics heir Reed Rubin is protesting a decision by the board of Roosevelt Island’s Four Freedoms Park to not include a donor inscription on the Louis Kahn-designed FDR memorial. For a $2.5 million donation in honor of Rubin’s parents Vera D. and Samuel Rubin, founders of the cosmetics firm and the Reed Foundation, the foundation claims it was promised an inscription in a prominent spot (preferably near the bust of FDR on a slab facing Manhattan).
The board of the park, not wanting to compromise the monument’s design, proposed an inscription in another location in the park. Rubin and the foundation are fighting back, and had tried to postpone October’s dedication. The New York Daily News quoted a letter written by the park’s board chairman William vanden Heuvel to the foundation: “You may prevail in a courtroom. But it will be a Pyrrhic victory, dear friends, a scar not a medal on the list of your achievements.”
Dear readers, Eavesdrop had the opportunity to explore Louisville, KY—our hometown—and Cincinnati, OH (a.k.a. Porkopolis) over the weekend. It’s been six or seven years since our last trip to Cincy and we have a couple things to say about it. It’s kind of a real city, like dense and old, with just enough corporate headquarters looming over the skyline.
We finally got to see the HOK designed Great American Tower in real life and it’s just as bad in person as its renderings. You may remember that we thoroughly made fun of its fugly, Princess Di inspired, steel tiara—something about lipstick on a pig. Let’s update that to a more current comparison. That tiara is more Honey Boo Boo than Princess Di. Eavesdrop is not a fan of hats or tiaras on buildings—i.e. the Pappageorge Haymes-designed One Museum Park in Chicago with its sailor cap. The American Institute of Steel Construction disagrees, recently giving said tiara a design award.
Last month in this column, we conjured up a fake rivalry between Cincinnati, Cleveland, and East Lansing, MI, as they all have high profile projects opening this fall. Of all the blabber we’ve scattered across these pages, that piece stirred up the most voices. One fan wanted to know, “What about Indianapolis?” In our opinion, it’s a classic quantity versus quality situation. There’s a lot of development going on in Indianapolis right now, including City Way, along with a lot of forgettable architecture. There was the opening of the JW Marriott, with its nifty, curved blue glass curtain wall, design by HOK and CSO Architects. But does a convention hotel really stand up against starchitect designed museums and boutique art hotels? Not in this case.

domain: news


CLEARWATER, FL (WFLA) – Some relief on the streets during the busy spring break season could be coming to Clearwater.
The city wants to work out a deal with the Clearwater Ferry to lower fares in an effort to reduce the number of cars on Clearwater Beach, said city spokeswoman Joelle Castelli.
The pilot program would cut fares from the current $3 one-way fare to $2.
It would run from March 1 to April 30, Castelli said.
The reduces fares would be available from 10:00 a.m. to 8:00 p.m.
The city must get the final agreement worked out in the next week.
The ferry departs Clearwater from Drew Street.


Salisbury City boss Darrell Clarke admits winning the Blue Square Bet South title will not be possible this season following Tuesday’s 2-0 loss to Basingstoke Town at the Raymond McEnhill Stadium.
The Whites occupied the top spot of the table for several months, but are now trailing Welling United by two points, having played three games more than the Wings.
Clarke is less than happy about his team effectively throwing away their hopes of winning the title this season.
“Now is the time for my players to stand up and be counted,” he told the Salisbury Journal.
“They’ve got to dig deep, and the team out there on Tuesday didn’t look like one of mine.
“The performance was poor and I don’t take very kindly to it.
“I need characters and there were none, it was definitely our worst defeat of the season. We’ve lost games perhaps we didn’t deserve to lose.
“But the league has gone. We’re miles away from the league title and that’s how realistic we’re.
“But what I must do is get the boys back to basics and get them believing again.
“We’ll continue fighting in every match. There were a lot of disappointed faces in the changing room as you can imagine.”
Posted: Thursday , March 07, 2013


text:
A shooting has hospitalized two people, landed a possible suspect in handcuffs and closed an Interstate 215 offramp near UC Riverside, police said.
The gunfire erupted Wednesday evening, March 13, at an apartment complex at 5310 Canyon Crest Drive, said Officer Bryan Galbreath.
A suspect wearing a Los Angeles Kings jersey and driving a white Toyota was spotted on I-215 north and was stopped by police on the University Avenue offramp, according to preliminary information.
No police officers were hurt.
“One victim was shot in an apartment,” said Galbreath. “And the other victim was a bystander. and a round entered his apartment and wounded him.”
No other details were immediately available.


text:
A child neurologist can effectively treat most children with epilepsy; however, about a third will have seizures that are treatment resistant after two tolerated, appropriate, anti-epileptic medications.Reference Kwan and Brodie1, Reference Kwan, Arzimanoglou and Berg2 These children, as well as those with focal onset epilepsy associated with an epileptogenic lesion on magnetic resonance imaging (MRI), are eligible for referral to a comprehensive pediatric epilepsy program (CPEP) for assessment of surgical candidacy.Reference Cross, Jayakar and Nordli3 Epilepsy surgery has better outcomes than continued medical management alone. Limited awareness of surgical treatment options, however, leads to inappropriate patient referral and underutilization of epilepsy surgery in potential candidates.
Patients with lesions on MRI such as focal cortical dysplasia (FCD) are likely to be referred to epilepsy centers by neurologists; however, many FCD lesions go undetected on MRI when reported outside of a major epilepsy center.Reference Salamon, Kung and Shaw4 Bowen et al. also reported that out of an estimated 5170 children with drug refractory epilepsy in Ontario between 2011 and 2016, 2800 (54%) received video electroencephalograph (EEG), while 2370 (45%) were discussed at seizure conference.Reference Bowen, Snead and Chandra5
FCD is a common cause of medically refractory, focal onset epilepsy in children. It may comprise as much as 25–40% of refractory childhood epilepsies, with increasing incidence as imaging technologies improve.Reference Lee and Kim6 FCD is the most common cause of epilepsy surgery in children less than 4 years of age.Reference Harvey, Cross and Shinnar7 The International League Against Epilepsy Sub-Commission for Pediatric Epilepsy Surgery identified FCD as one of the several etiologies and syndromes in children for epilepsy surgery evaluation.Reference Cross, Jayakar and Nordli3 It is a developmental, cortical migration disorder, classified by clinical–pathological criteria.Reference Blumcke, Thom and Aronica8 These malformations are epileptogenic and can occur anywhere in the cortex, gray–white matter junction, or adjacent subcortical white matter.
FCD Type 1 has been associated with cerebral hypoplasia or mild blurring of the cortical–white matter junction on MRI.Reference Colombo, Salamon and Raybaud9 Tassi et al., however, reported MRI to be uninformative in 22/66 (33%) cases of histologically confirmed FCD Type 1.Reference Tassi, Garbelli and Colombo10 MRI features of FCD Type 2 include cortical thickening, blurring of the gray–white matter junction, gyration anomalies, subcortical white matter signal change, or the transmantle sign.Reference Colombo, Salamon and Raybaud9 Results vary according to the subtype of FCD with 23/34 (68%) of FCD IIA and 61/66 (93%) of FCD IIB, correctly diagnosed on MRI.Reference Tassi, Garbelli and Colombo11 Another study from the same group reported a normal MRI in 19/37 (49%) of FCD IIA and 7 (9%) of FCD IIB.Reference Colombo, Tassi and Deleo12 A transmantle sign was significantly associated with FCD Type IIB.Reference Colombo, Salamon and Raybaud9, Reference Colombo, Tassi and Deleo12, Reference Barkovich, Kuzniecky and Bollen13 FCD Type III is a combination of abnormal cortical lamination with hippocampal sclerosis (Type IIIa), tumors (Type IIIb), vascular malformations (Type IIIc), or other acquired lesions (Type IIId). The dual pathology may be unappreciated on MRI, as the cortical lamination abnormality is often undetected.Reference Guerrini, Duchowny and Jayakar14
FCD has characteristic interictal EEG features. Rhythmic epileptiform discharges (REDs), rhythmic spikes or polyspikes, and repetitive bursts of fast waves (brushes) on scalp EEG correlate with continuous epileptogenic discharges (CEDs), rhythmic spikes or polyspikes and repetitive bursts of fast waves (brushes), observed during invasive monitoring using stereo-electroencephalograph (SEEG) or electrocorticography (ECoG), in patients with cortical dysplasia on histopathology.Reference Tassi, Garbelli and Colombo11, Reference Chassoux, Devaux and Landre15–Reference Palmini, Gambardella and Andermann17 Gambardella reported REDs in 15/34 (44%) and CEDs in 23/34 (67%) patients with cortical dysplasia compared with REDs in 0/44 (0%) and CEDs in 1/40 (2.5%) patients with non-dysplastic lesions.Reference Gambardella, Palmini and Andermann16
Brushes are significantly associated with the balloon cells of FCD IIB.Reference Tassi, Garbelli and Colombo11 Regional polyspikes on interictal scalp EEG were more often associated with FCD on MRI, than other regional interictal discharges.Reference Noachtar, Bilgin and Remi18
EEG biomarkers for FCD are specific but not very sensitive. The sensitivity of REDs to detect FCD compared to histopathology was 15/34 (44%) with a specificity of 40/40 (100%), and the sensitivity of regional polyspikes to detect FCD compared to MRI was 10/34 (29%) with a specificity of 460/479 (96%).Reference Gambardella, Palmini and Andermann16, Reference Noachtar, Bilgin and Remi18 The low sensitivity FCD findings on scalp EEG are probably explained by the well-known phenomenon of attenuation or distortion of cortical potentials by the tissues overlying the brain.Reference Gambardella, Palmini and Andermann16
Knowing the strengths and limitations of the tests of FCD is important when considering patients with focal onset epilepsy for surgical referral.
The goal of this study was to assess whether detection of FCD on MRI or prolonged interictal scalp EEG in children with focal onset epilepsy was associated with referral to a CPEP. Our hypothesis was that interictal focal polyspikes, fast waves, or REDs detected on prolonged scalp EEG and FCD on MRI are recognized by referring physicians as biomarkers of FCD, and that their detection is associated with referral to a CPEP for surgical evaluation. This study also aimed to identify other diagnostic predictors of referral to a CPEP.
We performed a single-center, retrospective health record review of children referred for prolonged scalp video-EEG monitoring at McMaster Children’s Hospital. The pediatric neurologists who read and reported the EEGs participated in the study. The Hamilton Integrated Research Ethics Board approved the study (REB Application Number 2018-0860).
The study included children with focal onset epilepsy, between 1 month and 18 years of age, who completed a prolonged (>1 h) scalp EEG and had a brain MRI performed after 2 years of age at McMaster Children’s Hospital between 2008 and 2015.
Children with generalized onset epilepsy or generalized epilepsy syndromes and with EEG diagnoses of electrographical status epilepticus in sleep, childhood epilepsy with central temporal spikes, multiple independent spike foci, Lennox–Gastaut Syndrome, non-epileptic seizures, or MRI diagnosis of tuberous sclerosis complex were excluded from the study. Children with Lennox-Gastaut Syndrome were excluded from the study, even though some of these patients have focal onset epilepsy, due to the presence of paroxysmal fast activity seen on EEG in this epilepsy syndrome.
Each patient’s neurology clinic reports were reviewed for seizure and epilepsy types, epilepsy syndromes, etiology, CPEP referral, epilepsy surgery, and pathology. Prolonged (>1 h) scalp EEG reports were reviewed and categorized for interictal focal polyspikes, fast waves, or REDs. We elected to only assess the prolonged video-EEG studies, since the duration of recording has been shown to increase the yield of detecting interictal discharges.Reference Narayanan, Labar and Schaul 19
The MRI reports were reviewed for the presence or absence of FCD, malformations of cortical development other than FCD, tumor, stroke, vascular malformation, or mesial temporal sclerosis. All imaging sequences were obtained using a 1.5 Tesla (T) MRI.
Focal polyspikes (Figure 1): Interictal polyphasic spikes occurring at one or a few neighboring electrodes on EEG.
Focal fast waves (Figure 2): Interictal beta waves occurring at one or a few neighboring electrodes on EEG.
Rhythmic epileptiform discharges (Figure 3): Interictal stereotyped rhythmic sequences of repetitive sharp waves or spikes, lasting more than 1 s without clinical signs.Reference Gambardella, Palmini and Andermann 16
Focal cortical dysplasia: Cortical thickening, blurring of the gray–white matter junction, gyration anomalies, subcortical white matter signal change, or a transmantle sign on MRI.Reference Colombo, Salamon and Raybaud 9 , Reference Colombo, Tassi and Deleo 12
The primary outcome measure was referral to a CPEP by a pediatric neurologist or pediatrician, and the secondary outcome was epilepsy surgery. The following variables were included in the analysis: sex, age of seizure onset, age at first prolonged scalp EEG and first MRI after 2 years of age, duration of prolonged scalp EEG, response to medication, signs of FCD on interictal scalp EEG, MRI diagnosis, and etiology. MRI diagnosis included FCD, malformations of cortical development other than FCD, tumor, stroke, vascular malformation, or mesial temporal sclerosis.
Categorical and continuous variables were analyzed with 95% confidence intervals, using the chi-squared and student’s t-test, respectively, with SPSS Statistics, Version 25. The variables were also analyzed using a logistic regression model.
Two hundred and seventy children who completed a prolonged scalp video-EEG between 2008 and 2015 were evaluated for enrollment. Of these, 68 were included in the study.
Of the study cohort, there were 15/68 (22%) with FCD on interictal scalp EEG, 22/68 (32%) with FCD on MRI, and 7/68 (10%) with FCD on both. The MRI reports for EEG-only-positive patients were not suggestive of FCD at any time on 1.5 T MRI, even though several patients had multiple MRI scans. For those with MRI evidence of FCD only, the interictal EEGs typically reported rare, intermittent, or frequent focal sharp waves, sharp and slow waves, or spike and waves. Focal delta or theta waves were also occasionally reported. When EEG findings of FCD were evident, they were reported in the body of the report. The report impressions focused on localization of the ictal onset and irritative zones. The EEG findings of FCD were correlated in the report with either a structural etiology or FCD in 6/15 cases.
Treatment resistant epilepsy was present in 12/15 (80%) patients with EEG markers of FCD, 18/22 (81%) with FCD on MRI, and 7/7 (100%) of those with both markers. There was no difference in response to epilepsy treatment between those with the EEG marker and those with MRI findings of FCD. Differences in seizure frequencies between the groups were not recorded in the study, as this was not consistently reported in the medical charts.
Thirty-seven of the 68 (54%) cases were referred to a CPEP. The referring physicians were pediatric neurologists or pediatricians. Of these, 9/37 (24%) had signs of FCD on interictal scalp EEG, 19/37 (51%) on MRI, and 6/37 (16%) with FCD on both. For patients with both findings, they were discussed at seizure conference after the MRI was positive in five cases. One case was not referred.
All nine patients with FCD markers on EEG, referred for epilepsy surgery evaluation, had treatment-resistant epilepsy. Of the six patients with FCD markers on EEG not referred for epilepsy surgery evaluation, three had treatment-resistant epilepsy and the other three had treatment-responsive epilepsy.
Of the nine patients with FCD markers on EEG, referred for surgical evaluation, six included EEG findings of FCD or a structural etiology, in the impression of the EEG report, while in three, only the focal pattern of the EEG was discussed. Of the six patients with FCD markers of EEG, not referred for surgical evaluation, one included EEG findings of FCD or a structural etiology, while five only discussed the focal pattern of the EEG in the impression of the report.
The mean age of seizure onset was 84 months (SD 46 months) for the EEG-only patients, and 81 months (SD 49 months) for the MRI-only-positive patients (p = 0.88). These were not significantly different.
Thirty-one of the 68 cases (46%) were not referred. Of the patients not referred for epilepsy surgery, 17/31 (54%) had treatment-resistant epilepsy. There were 6/31 (19%) with signs of FCD on interictal scalp EEG (3 had treatment-resistant epilepsy and 3 had treatment-responsive epilepsy), 3/31 (10%) on MRI (1 with treatment-resistant epilepsy and 2 without), and 1/31 (3%) with signs of FCD on both (with treatment-resistant epilepsy). Signs of FCD on MRI were significantly associated with referral to a CPEP (p < 0.05), while signs of FCD on EEG were not.
Seventeen of the 37 (46%) referred to CPEP had epilepsy surgery. There were 3/17 (18%) with FCD on interictal scalp EEG and 7/17 (41%) with FCD on MRI who had epilepsy surgery, compared with 6/20 (30%) with FCD on interictal scalp EEG and 12/20 (60%) with FCD on MRI who did not. Neither signs of FCD on interictal EEG nor MRI were significantly associated with epilepsy surgery.
Of the six patients with FCD on both interictal scalp EEG and MRI referred for surgical evaluation, two underwent surgery. Pathology was reported as ganglioglioma in one patient and not available in the other. Of these patients who did not undergo surgery, one declined surgery, one was unable to tolerate intracranial monitoring, and two were not surgical candidates due to the inclusion of eloquent cortex within the epileptogenic zone. Of the eight patients with FCD on EEG only, three were referred for surgical evaluation and one had surgery, which was found to be a dysembryoplastic neuroepithelial tumor on pathology. One was not a surgical candidate and the other required further evaluation. Out of the 15 patients with FCD on MRI, only 10 were referred for surgical evaluation. Epilepsy surgery was undertaken in five, with one case of FCD, one of subcortical gray matter heterotopia, and two with ganglioglioma on pathology. Epilepsy surgery was not performed due to response to medication in four, eloquent cortex within the epileptogenic zone in one, inability to capture the ictal onset zone in one, and an unknown reason in another case. Of those with FCD neither detected on EEG nor on MRI, 15 were referred for surgical evaluation and 8 underwent surgery. Histopathology included hippocampal sclerosis (1), oligodendrogliosis (1), FCD IIA (1), gliosis (2), and non-specific pathology (1).
The cohort was evaluated for predictors of referral to a CPEP. The results are tabulated in Table 1. Fifty-two of 68 (76%) had medical refractory epilepsy. Of these, 35 out of 52 (67%) were referred to a CPEP. Medically refractory epilepsy was significantly associated with referral to a CPEP (p < 0.05).
Children with focal onset epilepsy were tabulated according to epilepsy surgery referrals and nonreferrals, surgery vs. no surgery. The results were compared with respect to gender, age at seizure onset, age at first prolonged scalp EEG, EEG duration, FCD biomarkers on EEG and MRI, age at MRI, MRI diagnosis, etiology, and medication failure (AVM – arteriovenous malformation, MCD – malformations of cortical development, MTS – mesial temporal sclerosis, N – number, SD – standard deviation). Bold values show p values of < 0.05.
There were 8/64 (12%) cases diagnosed with tumor on MRI. Seven of eight (88%) were referred to a CPEP, while 1/8 (12%) was not. Tumor on MRI was significantly associated with referral to a CPEP (p = 0.04). There was no significant difference in referral to a CPEP or epilepsy surgery when sex, age of seizure onset, age at first prolonged scalp EEG, age at first MRI, duration of scalp EEG, etiology and MRI diagnosis of malformations of cortical development, stroke, vascular malformation, or mesial temporal sclerosis were evaluated.
Logistical regression analysis was performed. FCD on MRI was significantly associated with referral to a CPEP with an odds ratio of 7 (CI 2.04–24.06, p < 0.01).
This study found that children with focal onset epilepsy were more likely to be referred for surgical evaluation if they were medically refractory, or were diagnosed with FCD or tumor on MRI. Referring physicians are probably familiar with these indications for referral. Children with focal onset epilepsy and signs of FCD on prolonged scalp EEG, other structural lesions on MRI, or non-lesional medically refractory epilepsy were not more likely to be selected. This suggests that there is less awareness among physicians of the scalp EEG signs of FCD and the fact that FCD I, IIA, and III may be missed by MRI alone. A free online tool developed by the CASES expert panelists, using evidence and consensus opinions, is a useful guide for physicians in identifying children with focal epilepsy who may benefit from epilepsy surgery evaluation.Reference Jette, Quan and Tellez-Zenteno 20
Signs of FCD on interictal EEG or MRI were not significantly associated with epilepsy surgery. This suggests that other factors play a role in determining surgical candidacy. These include further investigations with high resolution, epilepsy protocolled MRI, fluorodeoxyglucose positron emission tomography, magnetoencephalography, ictal single-photon emission computed tomography, invasive monitoring with ECoG or SEEG, and high-frequency oscillation analysis, as well as neuropsychological testing and localization of eloquent cortex with functional MRI, and discussion at seizure conference in a CPEP.Reference Guerrini, Duchowny and Jayakar 14 The potential epileptogenic zone may include eloquent cortex, which excludes epilepsy surgery as an option for some patients.
This study is limited by its retrospective, single-center design, relatively small sample size, use of 1.5 T MRI, and the number of subjects without MRI or EEG markers of FCD. The MRI and EEG data were collected from the patient’s medical records without being reviewed objectively by the research physicians. The detection of FCD on MRI may therefore have varied between radiologists. The EEGs were originally read by one of the two study neurologists; however, the report impressions tended to emphasize the location of the interictal discharges rather than correlating clinically with a structural etiology or FCD. This may have limited the recognition of FCD and decision for referral by the primary neurologist. Referral paths also changed during the course of the study. The Hospital for Sick Children (Sickkids) in Toronto was the epilepsy surgery center for children in the Hamilton region between 2008 and May 2014. McMaster Children’s Hospital was designated a District Epilepsy Centre in May 2014 with Sickkids as the Regional Epilepsy Centre. These changes may have affected the referral rates for children with FCD.
Knowing how to detect FCD, and the criteria for epilepsy surgery referral in children with focal onset epilepsy is essential to limit inappropriate referrals and underutilization of epilepsy surgery in potential candidates. The use of the free online tool developed by the CASES expert panelists is a useful adjunct for primary physicians caring for children with epilepsy.
The authors thank the physicians, nurses and EEG technologists at McMaster Children's Hospital who cared for the patients presented in this study.
Conflict of Interest
The authors have no conflicts of interest to disclose.
Statement of Authorship
MSF reviewed patient health records, collected data, identified patients for inclusion, interpreted the data, drafted the initial manuscript, reviewed, and revised the manuscript.
Dr. BN performed the statistical analysis, interpreted the data, reviewed, and revised the manuscript.
Dr. MAN reviewed and revised the manuscript.
Dr. RR reviewed and revised the manuscript.
Dr. KCJ reviewed the patient data and revised the manuscript.

domain: medical


Coming in 2016, Porsche has just announced the 911 Turbo and Turbo S have been given a nip, a tuck, and a bit more horses.
Both the Turbo and Turbo S have been given power hikes.
The Turbo now has 540 horses, and the S gets 580.
Not a 63 times a 3 and 2.9 seconds respectively.
And top speeds have risen as well.
You'll get 198 in a turn about and 205 miles an hour in the S. Porsche is throwing a lot of standard gear at the new Turbo's: GPS, Climate, All Wheel Drive, Porsche Active Suspension Management, Porsche Stability Management, Porsche Active Aero Dynamics and Parking sensors.
[UNKNOWN] Gets a few more Porsche bits as well, Porsche dynamic chassis control and Porsche ceramic composite breaks.
It also sites on 20 inch center lock alloys, all very swish.
Now the name.
Yes, the current crop of 911s have smaller turbo engines so technically the base cars are turbo, too.
However the technology arrow and speed [UNKNOWN] in the proper turbos set them far apart.
The turbo may not be as hardcore as the GT3s and the like, but a punishing place mixed with top notch comfort.
The last turbo s was a mighty fast car but this new one, well if it's too slow for you, you might want to start looking at rocket sleds.
Rather than cars.
Is this tuned Toyota GR Yaris better than the original?
The Ford Mustang Shelby GT500 is sophisticated yet obnoxiously...
Rimac Nevera: An electric hypercar that sets the bar
The Zenvo TSR-S has a neat party trick with its active rear wing
The Aston Martin V12 Speedster is the coolest way to get flies...
BMW 128ti: A true rival to the Golf GTI
The Cupra Fomentor sets a high bar for the new brand
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Malaysia’s online hiring decline likely to slow in 2017: Page 3 of 3
By Digital News Asia January 25, 2017
Philippines’ recruitment outlook to remain positive
2017 is shaping up to be a positive year for online recruitment in the Philippines, as the upward trend of online hiring from the second half of 2016 continues into the New Year, according to Monster.com
The Philippines’ employment landscape enjoyed strong growth in overall hiring activity – most notably in the second half of 2016, where consistent positive annual growth in online hiring activity was recorded. According to the MEI, this paints a positive picture for the months ahead.
Overall, the Philippines got off to a slow start in 2016, when all industries collectively witnessed a -10% year-on-year dip in hiring activities in January. This was then followed by a -12% year-on-year decline in February – the steepest drop in the series.
In April, the country saw its first positive growth at 4% year-on-year, and continued to see consistent positive hiring trend for the rest of the year.
While there was a slight annual dip of -2% in September, recruitment activity quickly picked up from October. As of December 2016, the Philippines recorded 3% annual growth in online hiring activity.
“The local Philippine economy has held up relatively well against external storms in 2016 when compared its regional counterparts. This is attributed to the country’s sound fundamentals and other strong policies that were put in place, positioning the country as a shining spot for business opportunities and investments, and in turn greatly boosting job opportunities for locals, and the economy on the whole,” said Modi.
“In 2017, the country can expect to see a lot more spikes in employment activities, particularly at the start of the year where companies are warming up their engines for the new fiscal year ahead and will see a demand for fresh talent to facilitate operations, especially in the tourism, manufacturing and BPO sector. On top of that, the government has planned to create at least 1.2 million new jobs each year until 2022 to fully tap into the local untapped workforce, and will likely contribute to hiring numbers in 2017.”
Positive growth outlook for IT sector
Online hiring in the IT sector has also been positively stable over the last 12 months for the country. The MEI recorded a 12% year-on-year growth in online hiring in January, seeing its sharpest growth in April at 23% year-on-year. The year capped off with a 12% year-on-year growth in December 2016.
And the most sought-after skills by employers in 2016 are …
Hiring outlook in SEA IT sector hopeful, but Malaysia plunges: Monster
Explaining the shortage of IT pros in Singapore
For more technology news and the latest updates, follow us on Twitter, LinkedIn or Like us on Facebook.


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NEWS & EVENTS
Stay tuned for bookstore readings, panel discussions, book club events and new programs for libraries in 2021.
Sorry, nothing is happening now. All in-person events were cancelled. Stay in and stay healthy. Imagine all the fun and parties we'll have when it's finally over.
BookCon New York Javits Center, Dartfrog Press, Book Launch, signing and giveaway
The Big E (Eastern States Exposition), Connecticut Building with the Connecticut Authors and Publishers Association
Norwalk CT Library, Author Day
Branford CT Blackstone Library, featured website author “Snuggle In and Read Halloween Ball”
Fairfield Publish Library, Presenter, “From Pages to Publication Writers Conference”
Bethany Clark Memorial Library
Norwalk Public Library, Reading & Lunch
Hartford Literary Festival, Hartford Public Library

domain: library


HARARE – Acting President Constantino Chiwenga on Wednesday said only God knows how the coronavirus will end, as he made his first public appearance in a week for the burial of two cabinet ministers and a former prisons boss.
Chiwenga, who had been rumoured to be unwell, betrayed no such signs as he led proceedings at the unprecedented triple burial of foreign minister Sibusiso Moyo, transport minister Joel Biggie Matiza and former prisons chief Paradzai Zimondi at the National Heroes Acre, a hilltop cemetery in Harare.
The three died from Covid-19 which has killed four ministers, three of them in the last fortnight.
“One expects that when tragedy strikes, it would gradually abet but this is not the case, it is only God who knows when it will end,” the 64-year-old former army general said, speaking before a sparse audience of mainly family members of the trio and security officers.
He went on: “Today marks a tragic day for our country Zimbabwe. I want to express my pain over Covid-19.
“The virus has taught us an important lesson that we are all mortals. It does discriminate against the weak and the powerful, the privileged and the deprived, the haves and the have-nots. It is a ruthless juggernaut that leaves a trail of despair and desperation. But we will eventually conquer it and prevail as a people.”
Chiwenga, who doubles up as health minister, said the government “is already in the process of acquiring the necessary vaccines for this pandemic,” but gave no details.
Zimbabwe, a country of 15 million, is reported to be in talks with China and Russia to procure much-needed vaccines. Zimbabwe is also part of COVAX, the global pooled procurement mechanism for Covid-19 vaccines through which it hopes to secure jabs for at least two million of its citizens.
Chiwenga, who took over from Vice President Kembo Mohadi as Acting President for the last 15 days of January, was last week temporarily eased out of the presidency by President Emmerson Mnangagwa, who is on leave, over health concerns.
A spokesman for the presidency said Chiwenga was “worse for wear,” blaming his condition on exhaustion after he apparently worked long hours as Zimbabwe battles a resurgent virus which is killing at a higher rate since the start of the year.
On Tuesday, the ministry of health reported 358 new infections and 28 deaths. Zimbabwe has to date reported 32,004 coronavirus cases which have led to 1,103 deaths.
As of January 25, the country’s hospitals currently were holding 213 patients, of whom 139 were reported to be in mild or moderate condition, 62 severe and 12 were on life support.


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Biophysical Journal, Volume 16, Issue 5, 1 May 1976, Pages 433-439
The effect of the local anesthetic QX222 on the kinetics of miniature endplate currents and acetylcholine induced endplate current fluctuations was studied in voltage clamped cutaneous pectoris muscle of Rana pipiens. Both the endplate current fluctuation spectra and the miniature endplate current decay consisted of two or three components depending upon the holding potential and local anesthetic concentration. The cutoff frequency of each spectral component was equal to the decay rate of its corresponding constituent of the miniature endplate current. Comparison of the relative amplitudes of the spectral and miniature endplate components indicated that QX222 did not act by creating two kinetically distinct populations of acetylcholine receptors. QX222 action could be explained by alteration of the acetylcholine receptors such that they sequentially change conformation form one open state to another. A specific case in which QX222 binds to the open state of the acetyl-choline receptor creating a blocked state, was found to account for the observed relationship between the relative amplitudes of the miniature endplate current and spectral components, as well as the previously observed voltage and concentration sensitivity of the decay rates of endplate current components.
Abstract | PDF (385 kb)
Neuron, Volume 40, Issue 3, 30 October 2003, Pages 563-580
Linga V. Reddy, Samir Koirala, Yoshie Sugiura, Albert A. Herrera and Chien-Ping Ko
To investigate the in vivo role of glial cells in synaptic function, maintenance, and development, we have developed an approach to selectively ablate perisynaptic Schwann cells (PSCs), the glial cells at the neuromuscular junction (NMJ), en masse from live frog muscles. In adults, following acute PSC ablation, synaptic structure and function were not altered. However, 1 week after PSC ablation, presynaptic function decreased by approximately half, while postsynaptic function was unchanged. Retraction of nerve terminals increased over 10-fold at PSC-ablated NMJs. Furthermore, nerve-evoked muscle twitch tension was reduced. In tadpoles, repeated in vivo observations revealed that PSC processes lead nerve terminal growth. In the absence of PSCs, growth and addition of synapses was dramatically reduced, and existing synapses underwent widespread retraction. Our findings provide in vivo evidence that glial cells maintain presynaptic structure and function at adult synapses and are vital for the growth and stability of developing synapses.
Summary | Full Text | PDF (1726 kb)
Biophysical Journal, Volume 77, Issue 2, 1 August 1999, Pages 1177-1187
Joel R. Stiles, Irina V. Kovyazina, Edwin E. Salpeter and Miriam M. Salpeter
The temperature dependence of miniature endplate current (MEPC) amplitude (Ac), 20–80% rise time (tr), and 90–33% fall-time (tf) was determined for lizard (Anolis carolinensis) intercostal muscle using broadband extracellular (EC) and voltage clamp (VC) recordings. Voltage clamp methods were optimized for the fast MEPC rising phase using custom electronics. From 0–43°C, Ac increased by ∼4.2-fold, while tr and tf decreased by ∼3.6- and ∼9.5-fold, respectively. Arrhenius plots were smoothly curved, with small apparent Q10 (Ac) or (Q10)−1 (tr and tf) values mostly well below 2.0. Nearly identical extracellular and voltage clamp results ruled out measurement artifacts, even for the shortest tr values (<60μs). Monte Carlo simulation of MEPCs showed that a single underlying rate cannot determine the observed temperature dependence. To quantitatively reproduce the experimental tf results, a minimal model required activation energies of 46.0 (Q10∼2.0) and 63.6 (Q10∼2.5) kJ mol−1 for channel opening and closing, respectively, and accounted for most of the observed changes in Ac and tr as well. Thus, relatively large but offsetting temperature sensitivities of channel gating mostly govern and minimize the temperature dependence of MEPCs, preserving the safety factor for neuromuscular transmission. Additional temperature-sensitive parameters that could fine-tune the minimal model are discussed.
Abstract | Full Text | PDF (225 kb)
Copyright © 1985 The Biophysical Society All rights reserved.
Biophysical Journal, Volume 47, Issue 2, 183-202, 1 February 1985
J.R. Segal, B. Ceccarelli, R. Fesce and W.P. Hurlbut
A method based upon an extension of Campbell's theorem is used to measure the amplitude, waveform, and frequency of occurrence of miniature endplate potentials (mepps) at rapidly secreting neuromuscular junctions of frog cutaneous pectoris muscles. Measurements of the variance, skew, and power spectrum of the fluctuations in membrane potential are used to deduce the mepp parameters. These estimates of mepp amplitude and frequency are insensitive to slow drifts in membrane potential that preclude the conventional application of Campbell's theorem, which uses the mean and variance. The new method becomes unreliable at high mepp frequencies because the distribution of the values of membrane potential approaches a Gaussian thereby reducing the accuracy of skew measurements. Frequencies approaching 10(4) s-1 can be measured, however, if the data are high-pass filtered. The method has been tested with computer simulated data and applied to junctions exposed to La3+; the effects of Ca2+ on the La3+-induced secretion have been explored. Some muscles were fixed after treatment with La3+, and changes in nerve terminal ultrastructure were assessed by morphometric analysis of electron micrographs. Horseradish peroxidase was used to obtain information about vesicle recycling.

domain: biology


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Justice Inyang Ekwo of the Federal High Court in Abuja on Monday requested that the warrant of release issued in favour of two Nigerians detained by Police considering that October 5 be served on the Inspector Common of Police, Usman Baba Lawyer-Typical of the Federation, Abubakar Malami (SAN) and 4 some others.
The choose experienced on November 5, 2021 requested the IGP, the AGF, Joseph Egbunike (DIG) and the Deputy Inspector-General of Police, Power Legal Investigation Office Abuja to quickly launch Jude Osuhor and Happiness Edifie who experienced been clamped into detention at the FICID, Abuja since October 5.
Justice Ekwo’s buy of Monday for clean services of the previously order on the IGP and AGF was occasioned by complaint by Jibrin Okutepa (SAN), attorney to Jude Osuhor and Pleasure Efifie, that the police had refused to obey the courtroom order.
Okutepa complained to the courtroom that the IGP and other respondents in the basic rights enforcement suits by his consumers had been served with the court’s November 5 launch purchase, but that they had disregarded the buy.
He said whilst the circumstance was adjourned for hearing, the respondents refused to obey the court’s buy to launch the two detainees and also refused to show up in court docket.
Okutepa stated, “The purchase of this courtroom was served on the respondents because November 5 the IGP has refused to release them. We have applied for Kind 48 to initiate contempt charge versus him and dedicate him to prison.
“I don’t know why the IGP and DIG would convert by themselves into government sabotage of court buy.
“I want to implement for the court to get the IGP to come below and present lead to why he should not be sent to prison for disobeying courtroom purchase.”
Delivering his ruling, Justice Ekwo said he would rather give the IGP and other respondents the prospect to obey the court’s buy and occur to protect the case pending from them.
“I am minded to make an get to give the respondents sufficient time to comply with the court get and to allow them seem in court to protect the pending circumstances,” the decide said.
He then purchased the court’s Deputy Registrar, Litigation to deliver to the notice of the IGP and other respondents the pendency of the fits and ‘the order of this court built on November 5’.
The judge then adjourned till December 8 for listening to.
In the two suits marked: FHC/ABJ/CS/1289/2021 and FHC/ABJ/CS/1290/2021, the candidates are difficult their ongoing detention by the respondents above their alleged complicity in the demise of Osuhor’ spouse, Vivian.
Named as respondents in both of those cases are the IGP, the Nigeria Law enforcement Power, DIG Joseph Egbunike, Ms. Loveth Edifie, the Deputy Inspector Common of Police, Drive Prison Investigation Division, Abuja and the AGF.
Jude Osuhor and Joy Efifie ended up arrested in Lagos on Oct 2, 2021 by operatives of the Nigeria Law enforcement Power from the FCID in Abuja.
Happiness is the quick young sister of the deceased and had lived with her late sister and her husband for many years in their Lagos dwelling.
According to court docket documents, Jude and Pleasure have been transferred from Lagos to Abuja on October 4 and ended up in the beginning granted bail on Oct 5.
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Contact: [email protected]

domain: politics


A breathtaking drama, with the “sudden shift of Ukraine towards Moscow,” has left the audience standing by with bated breath. No one understands what is really happening, but after the Cabinet ordered a stop to preparing for EU Association, recent EU-integration optimists went into the streets to try to defend their dreams. This scenario, in our view, has spoiled the game Yanukovich was trying to play with the EU and Russia, in hopes of goading them into competing for his decision at Vilnius Summit. More about recent tendencies you can read in our new report “Fumbling the Euro-Bluff”. The full report could be obtained through subscription at Global Source (www.globalsourcepartners.com). Trial access is available.


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2017 NYE Family Event-Dave and Buster's Arundel Mills/Store #035
Dave & Buster's
7000 Arundel Mills Cir, Hanover, MD 21076, USA
This event has already passed by. Sorry.
Event DescriptionBring in the New Year with your family at Dave and Buster's Special Family FUN Event! there will be a buffet of your favorite foods, beverages, power cards, entertainment, dance music, face painting, countdown, and more!
Come enjoy fun games and win prizes and raffles for the whole family. Tickets are priced per person. No separate children pricing. Space is limited.


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Gov. Brian Kemp signed two executive orders extending the Public Health State of Emergency and existing COVID-19 safety measures on Monday, just one day after the Georgia Department of Public Health reported a new daily high of positive cases.
The DPH reported 2,225 new cases on Sunday, which eclipsed the previous highest daily total of 1,990, a mark set just one day earlier. On Monday, the DPH reported 2,207 new positive tests, just shy of Sunday’s total.
Overall, Georgia’s COVID-19 total climbed to 79,417 positive cases, 10,824 hospitalizations and 2,784 deaths on Monday.
Gordon County’s total climbed to 356 confirmed cases on Monday, with 43 hospitalizations and 18 deaths reported locally. Those numbers represent an increase of 58 positive cases and four hospitalizations over the past week.
The Georgia Department of Public Health issues daily reports at 3 p.m. That report and additional data can be found online at dph.georgia.gov/covid-19-daily-status-report.
Kemp acknowledged the climbing numbers on Monday.
“While we continue to see a decreasing case fatality rate, expanded testing, and adequate hospital surge capacity, in recent days, Georgia has seen an increase in new cases reported and current hospitalizations. Given these trends, I am extending previous COVID-19 safety requirements and guidelines that were due to expire on June 30 at 11:59 p.m. Dr. Kathleen Toomey and the Department of Public Health, along with our local public health partners, will continue to monitor ongoing cases and related data to ensure that we are taking appropriate measures moving forward. Together, we can win the fight against COVID-19 and emerge stronger,” the governor said in a statement.
Executive Order 06.29.20.01 extends the Public Health State of Emergency through 11:59 p.m. on Tuesday, Aug. 11. The Public Health State of Emergency allows for enhanced coordination across government and the private sector for supply procurement, comprehensive testing, and healthcare capacity.
Executive Order 06.29.20.02 continues to require social distancing, bans gatherings of more than 50 people unless there is six feet between each person, outlines mandatory criteria for businesses, and requires sheltering in place for those living in long-term care facilities and the medically fragile. The order also outlines that the State Board of Education must provide “rules, regulations, and guidance for the operation of public elementary and secondary schools for local boards of education” in accordance with guidance from Toomey, the Department of Public Health, and the American Academy of Pediatrics. The order runs through 11:59 p.m. on Wednesday, July 15.
The surge in infections comes about two months after Georgia began lifting restrictions April 24 on hair salons, gyms, bowling alleys and other businesses that had been forced to close to slow the virus. Restaurants, retail stores and bars have since reopened as well.
Health officials believe the actual number of infections is likely far higher because many people have not been tested, and studies suggest people can be infected with the virus without feeling sick.
For most people, the coronavirus causes mild or moderate symptoms, such as fever and cough that clear up in two to three weeks. But for others, especially older adults and people with existing health problems, the virus can cause more severe illness and even death.


The high-quality Copper Pearl high-quality infant bib in Europe and the United States, using Fleece super absorbent micro-wool polyester fiber on the back, soft and comfortable to touch, strong water absorption, can ensure the baby's dry and comfortable all day long. The front is made of high-grade 100% cotton fabric, stylish and unique print, how to match it is super-type!
The multi-functional chair cover of the European and American mommy circles has a variety of practical functions!
The elasticity is excellent, no matter the child seat or the cart can be easily covered, to prevent the dirty bacteria from running directly to the baby; there is a layer of protection, the wire on the cart will not stab the baby. In addition, as a windshield can prevent the baby from being directly exposed to the sun or the wind, but also can block the dirty things from running in. The comfortable and breathable material is not afraid of the baby being stuffy inside.
Of course, it can also become a breastfeeding towel, which is convenient for mommy to feed outside. Can also be used as a scarf when not wearing a breastfeeding towel!
◎Product Information ◎
Material: 96% rayon, 4% elastic fiber
Brand: United States
Size: about 70X70 CM


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Dog's toenails are always growing, which makes it important for owners to have them trimmed regularly. Many don't realize the importance of trimming their dog's nails, but proper trimming affects the entire musculoskeletal system of your canine friend. Unless you are experienced, have your vet show you how to trim your dog's nails before attempting it yourself.
Anatomy of Dogs' Nails
As with human fingernails, a dog's nails are made of a hard, fibrous material called keratin. The inner part of the nail is called the quick. The quick is soft, often pinkish, and has nerves and blood cells. While it is important that your dog's nails are kept trim, it is equally important that they are not cut too short, as cutting the quick will cause your canine pain and bleeding.
Recognizing the Different Parts
Some dogs have black nails while others have clear or white ones. It is generally much easier to tell the difference between the outer shell and the quick on the lighter nails, as the pinkish quick part should be more clearly visible. If your pet's nails are dark, it may be more difficult to discern. Sometimes a dog may have one white nail, while the rest are black. In such a case, the white nail can sometimes serve as a guideline for trimming the other nails, if used with caution. Again, it's important to have your vet show you first.
Trim a dog's nails to about two millimeters in front of the pink quick. This will allow them to be trimmed down to an appropriate size without cutting into the quick or leaving it exposed and vulnerable. When a dog walks, he should be able to put his paw pad down on the ground first and then to "kick off" with his toenails before lifting them off the ground. If the nails are too long, he won't be able to stand or walk properly.
Problems With Untrimmed Nails
If a dog's nails are not trimmed appropriately, it can cause him to stand "splayed-footed," or with his toes spread out. This can cause your dog pain when walking, and will force him to put more weight to the rear of his foot. Over time, this can create anatomical problems for the dog, as parts of his musculoskeletal system will being taking on work that they were not designed for. This can create long term pain for your pet.
Brian McCracken lives in Portland, Ore., where he writes on pets and animal wildlife as well as a wide array of other topics, ranging from real estate to personal development.

domain: pet