Tablets & eReaders
Home & Garden Appliances
Sports & Outdoor
Kids & Baby Gear
Price Low To High
Price High To Low
TomTom ONE 130S - US & Canada Automotive Mountable GPS Receiver
The TomTom ONE 130S GPS receiver provides you with accurate and precise map details. The anti-glare screen on this TomTom GPS receiver offers easy viewing ability even in sunlight. This automotive GPS...
Simple setup and use, Clear directions, Voice navigation, Color screen, Easy to mount
On-screen buttons are kind of small, Volume doesn't get high enough for noisy situations
TomTom (9S00.000) Carrying Case for ONE XL
This case is designed for use with the TomTom ONE XL.Protect your TomTom ONE from bumps and scratches with this specially-designed carry case. Compact and durable, it combines good looks with practica...
TomTom ONE Classic Automotive Mountable GPS Receiver
The TomTom ONE Classic is an entry-level, basic automotive GPS receiver that is packed with features. The 3.5-inch touchscreen of this TomTom GPS device aids in easy map viewing. Exchanging routes and...
TomTom ONE 125 - USA Automotive Mountable GPS Receiver
TomTom ONE 125's distinctive design puts a full-size touchscreen and the power of GPS in a slim, lightweight device. Switch on and go right out of the box.
Easy to learn
Quickly changes directions in route
MapShare updates keep map current
Minor disagreements with the routes chosen
School Listings wildly inaccurate; most missing in my area
TomTom Navigator 5 Handheld
The GPS receiver uses Bluetooth technology to eliminate the need for connecting cables, and a new, high performance GPS antenna to ensure the best possible reception wherever you go.
Bluetooth, high performance receiver, software interface, 3D view, coverage, rerouting speed, stability
Installation, documentation, limited number of predefined POIs, car charger only, no voice commands
TomTom ONE XL S - US (including Puerto Rico), Canada Automotive Mountable GPS Receiver
Featuring Map Share technology, the TomTom ONE XL S GPS receiver allows you to make changes in the map and share it with the device customer. The 50 maps of the US and Canada are all stored in the 1GB...
TomTom ONE IQ Routes Edition Region Automotive Mountable GPS Receiver
The TomTom ONE IQ Routes Edition Region is an automotive receiver that provides you with directions on a wide, 3.5-inch screen. Save time and fuel, and reach your desired destination faster, using the...
TomTom Runner - Dark Grey GPS Watch
The TomTom Runner GPS Watch is slim fitting but still has a large and easy to read display. It makes achieving your training goals easy with the Graphical Training Partner.
TomTom 1H50080 Car GPS Receiver
Go wireless with TomTom Navigator Bluetooth for your Windows Mobile handheld device. Find your way without asking for directions or fumbling maps. This is a complete in-car navigation solution with cl...
Beautiful & intuitive GUI, clear & loud instructions
Dumb keyboard (A,B,C), voice not say street names, no map stitching
TomTom GO 500 Automotive Mountable GPS Receiver
Never again lose track of your destination with the TomTom GO 500. This TomTom car navigator includes the Europe maps; so you have in-depth knowledge of the nooks and corners of the continent. Now con...
TomTom Rider v2 GPS Receiver
Designed with bikers in mind rugged and waterproof TomTom RIDER comes with RAM mounting hardware that fits almost any bike and a Cardo scala-rider wireless headset for high quality voice instructions ...
Designed specifically for motorcycling, sturdy, waterproof, vibration resistant, RAM mount, Cardo Scala Rider headset
Little bulkier than standard units, expensive at $700
TomTom ONE 140 Red - US (including Puerto Rico), Canada & Mexico Automotive Mountable GPS Receiver
The Go EasyPort mount of the TomTom ONE 140 Red GPS device offers maximum portability. With built-in maps of US, Canada and Mexico, this TomTom automotive GPS receiver gives you greater convenience by...
Easy to use, reasonably priced, responsive touch screen, good bang for the buck.
Doesn't offer a lot of frills.
TomTom GO LIVE 1535M US Canada & Mexico Automotive Mountable GPS Receiver
Get real-time updates from the TomTom Go Live feature of the TomTom GO LIVE 1535M GPS receiver. You can easily connect your compatible mobile phone to this automotive GPS receiver for handsfree callin...
Voice commands, Driver Voice activation, Blue Tooth, Good Screen Size, Built-In Suction Cup
TomTom ONE 140S - US (including Puerto Rico), Canada & Mexico Automotive Mountable GPS Receiver
The TomTom ONE 140S offers up-to-date mapping and complete navigation for US (including Puerto Rico), Canada and Mexico in a compact package. With spoken turn-by-turn directions and 3D maps, this auto...
-small screen size
-volume automatically adjusts above 40mph
-screen colors change at night
-reads abbreviations literally instead of reading the correct word
-mount could be better
TomTom XXL 540S - Customized Maps Automotive Mountable GPS Receiver
The TomTom Car GPS is the perfect companion for a hassle free drive. This portable GPS system has a 5 inch, full color LCD widescreen touch display. Alongwith the MapShare feature, there are map views...
most of the maps are right on and TomTom provides a method for submitting corrections.
TomTom did not recognize that a road designated FR means Forest Road or Fire Road
TomTom Navigator 4 Automotive Mountable GPS Receiver
Never again lose track of your destination with the TomTom 1T50.080. This TomTom PDA navigator includes the US and Canada maps; so you have in-depth knowledge of the nooks and corners of these states....
The con has devoured any pros the first day.
Fish heads smell better than this software.
TomTom 9T00.002 Handheld GPS Receiver
The GPS receiver uses Bluetooth technology to eliminate the need for connecting cables, and a high performance GPS antenna to ensure the best possible reception wherever you go. The high performance G...
Small, light weight, tried and tested GPS Receiver, fast acquisition-time.
There is no early indication that your battery is low. Battery lasts only 4-5 hours.
TomTom XL 340 GPS Navigation System with Bonus Kit (New in Non-Retail Packaging) (Tom Tom XL 340 4.3 Inch Portable GPS Navigator with a complete bonus kit) 1EM0.052.01
$92.99 at Overstock.com
The TomTom XL 340 offers complete widescreen navigation with the most accurate maps in a compact, portable device with a 4.3 inch WQVGA touchscreen Automotive GPS guides you to any address in the Unit...
TomTom VIA 1505 TM Automotive Mountable GPS Receiver
$209.95 at FactoryOutletStore
TomTom VIA 1505TM with Lifetime Maps and Traffic Brand New Includes One Year Warranty, Product # 1EN501903, GPS Vehicle Navigation System, 5 Extra-Wide LCD Touchscreen, Lifetime Traffic & Map Updates,...
TomTom XL 325S - USA Automotive Mountable GPS Receiver
Plug the TomTom 325S GPS receiver, tap the screen, and your ready to explore while you drive. The XL 4.3-inch screen of this TomTom automotive GPS offers superb navigation comfort. Just focus on your ...
See Next Results
Free 2 Day Shipping
Rage Enterprises, LLC
3D Map View
Lifetime Map Updates
Lifetime Traffic Updates
Heart Rate Monitor
JPEG Image Viewer
Wireless Receiver Module
Bluetooth Wireless Technology
Real-time Traffic Reports
Time of sunrise/sunset
Avoid toll roads
Most use of freeways
Least use of freeways
Car Power Adapter
Vehicle Power Adapter
Buttons on Unit
USA (incl. Hawaii & Alaska)
The Russian Federation
Voice Navigation Instructions
Spoken Street Names
Low Battery/Voltage Alarm
Water Temperature Alarm
Map cartridges / Data cards
North America Maps
City Navigation Maps
Middle East Maps
South Africa Maps
South America Maps
Western Europe Maps
480 x 272
320 X 240
64 X 100
640 X 480
240 X 320
272 x 480
128 x 160
128 X 64
160 X 240
120 X 160
240 X 160
800 x 480
480 x 800
800 x 600
480 X 640
240 x 400
100 X 64
240 X 360
320 X 234
234 X 320
$0 - $345
$345 - $690
Copyright © 1999-2015 eBay Inc. All Rights Reserved


1-1/4" Bridge Reamer or Boiler maker or Rivet Hole or Alignment reamers with Morse Taper Shank HSS x .9375" small end dia x 3-9/16" tapered length x 7-3/8" flute length x 13" overall x 4 MTS
They have taper-lead of 1:10 over 1/3rd of cutting length for heavy duty construction work for rectifying misalligned holes, some sizes have MTS one size larger than usual.In HSS Excellent quality British-made to BS122
Click on Bridge Reamers Inch to buy all other sizes from 3/8" to 2"
Click on REAMERS to view our full range of Hand, Machine, MTS, Long, Taper-pin, Bridge, Chucking, Adjustable etc
- View what customers say about Us Satisfied customers include Rolls Royce, British Petroleum, Exxon Mobil Chemical, British Airways Avionics, Scottish Power Energy, etc


text:
Presenting his sportswear line, Adam + Eve, for the second time, Adam Lippes chose the Banchet Flowers shop in the far West Village as his venue. This made for a cramped, if fragrant, show location. But despite the crush, the clothes looked smart. Inspired by the rich fabrics and photographs from a long-ago trip to Kenya, Lippes balanced an organic, natural element—with obvious African roots—with his all-American sensibility. This juxtaposition of earthy and clean came to life in a knockout cream satin shift with distressed-metal embroidered trim.
A bright, Afro-centric print on cotton voile was cut into a breezy blouse and paired with crisp pleated shorts. Thick, embroidered cotton eyelet, meanwhile, was hand-painted white to give it a touch of earthy texture, and it showed up in a strapless top as well as a ladylike dress. Combining a bit more sophistication with a solid dose of the sporty edge on which he founded his line, Lippes' collection is evolving each season.

domain: design


Today in Ohio, in the middle of America, the middle class wonBrown defeats DeWine in Ohio Senate race Nov 08, 2006
The president carries a credibility gap on Medicare, on Iraq, on the budget deficit, and on the economy. The problem is that George Bush refuses to focus on the working families struggling to make ends meet in Ohio and across AmericaOhio Dems blast Bush on job losses Mar 24, 2004
Our interest is for seniors with prescriptions to be able to go to CanadaHouse considers re-importation of drugs Jul 25, 2002
You do your job, and you do your political things you need to do for five years, and you're readySenate Dems raise cash now for 2012 Apr 20, 2010
Some Wall Street people have said the longer they can delay this, the more chance they can kill itReid plans to go ahead with reform vote Apr 25, 2010
Sherrod Campbell Brown (born November 9, 1952) is the senior United States Senator from Ohio and a member of the Democratic Party. Before his election to the U.S. Senate, he was a member of the United States House of Representatives, representing Ohio's 13th congressional district from 1993 to 2007. He previously served as Ohio Secretary of State (1983–1991) and a member of the Ohio House of Representatives (1974–1982).
Brown defeated two-term Republican incumbent Mike DeWine in the 2006 U.S. Senate election. In the U.S. Senate, he is chairman of the Agriculture Subcommittee on Hunger, Nutrition and Family Farms and the Banking Subcommittee on Economic Policy, and is also a member of the Committee on Appropriations, Committee on Veterans' Affairs, and Select Committee on Ethics.
Brown was born in Mansfield, Ohio to Emily Campbell and Charles Gailey Brown, M.D. He was named after his maternal grandfather. He became an Eagle Scout in 1967. He received a Bachelor of Arts degree in Russian studies from Yale University in 1974. At Yale, he was in Davenport College, the same residential college as U.S. Presidents George H. W. and George W. Bush. He went on to receive a Master of Public Administration degree and a Master of Arts degree in education from the Ohio State University in Columbus in 1979 and 1981, respectively. He taught at the Mansfield branch campus of The Ohio State University from 1979 to 1981.


text:
Referees are swayed by outcome rather than intent
The words Jaco Peyper used when explaining his decision not to sin-bin Waisake Naholo for taking out Liam Williams in the air were: “He landed on his legs so it’s just a penalty.”
Peyper was correct in that Williams did land on his legs, and he was very fortunate not to suffer further injury.
But the outcome should not have determined whether Naholo was shown a yellow or even a red card. Many Irish fans felt CJ Stander was only sent-off against South Africa last week because his challenge on Patrick Lambie left his opponent unconscious, and this was perhaps another example of the end result having a bearing on the referee’s decision.

domain: news


Toyota is looking to shift production of the Prius hybrid to its Mississippi assembly plant when the next variant of the car arrives – in 2016.
Toyota was planning on building the car at the site originally, until GM exited the NUMMI plant in California, forcing GM to move Corolla production to their Deep South facility.
“The main components for the Prius — such as the motor and battery — are not mature enough for local production,” Executive Vice President Atsushi Niimi told Reuters. “We expect that they’ll be ready with the next remodelling.”
Technology issues aside, Toyota also feels that the U.S. economy has yet to fully recover, and that it won’t be prudent to launch a new vehicle any time soon.
“If you look at unemployment, housing, and other economic indicators there’s not much good news. I think it will take time for the market to recover,” Niimi said.


text:
Liam Neeson's big-budgeted action film is coming to Netflix this June.
Get ready because the man with particular sets of skills is coming back on another epic rescue mission, this time, in a literally frozen road.
'The Ice Road' is one of Netflix's biggest purchases in the European Film Market, along with Christian Bale’s 'The Pale Blue Eye' and Colin Firth’s 'Operation Mincemeat.' The streaming giant snatched the deal from other competitors for a whopping $18M.
'The Ice Road' stars Liam Neeson and will be written and directed by Jonathan Hensleigh. Hensleigh has notable credits for writing box office films, 'Die Hard With a Vengeance,' 'Jumanji,' and 'Armageddon.' He also wrote and directed the 2004 action movie 'The Punisher' starring Thomas Jane.
'The Ice Road' is coming to Netflix on June 25, 2021. Netflix confirmed the upcoming film's release date alongside first look photos of the movie.
Liam Neeson— NetflixFilm (@NetflixFilm) April 27, 2021
THE ICE ROAD
After a remote diamond mine collapses, a trucker leads an impossible rescue mission over a frozen ocean. Co-starring Laurence Fishburne, Benjamin Walker, Amber Midthunder and Marcus Thomas. On Netflix in the US June 25. pic.twitter.com/Nzltuux1cY
The film is already confirmed to release in the US, but we are still verifying its availability in other regions.
'The Ice Road' has already completed production as of March 2020 in Winnipeg, Ile-des-Chenes, and Gimli. Filming lasted only three months (from January to March 2020), and the team managed to wrap up before the COVID-19 pandemic hit the world.
Producer Bart Rosenblatt revealed some of the tricks they used in order to get the film's icy aesthetic to come to life.
“We laid water down, and then actually, even though it looks like it’s just ice, it’s all been painted with ice paint. I know that Liam Neeson and Laurence Fishburne all thought, and all of us thought it was really otherworldly being out on the ice." producer Bart Rosenblatt said in an interview with Winnipeg news.
Liam Neeson plays an expert driver who takes an impossible mission to rescue trapped miners after a remote diamond mine collapses. Liam must traverse the dangerous frozen ocean to complete the mission, but the thawing waters and unforeseen threats will make the task even harder.
“The only way to get the equipment up to save the miners is to take it on the ice roads with three 18-wheelers," Producer Bart Rosenblatt said.
'The Ice Road' is produced by Aperture Media, the same company behind 'The Trial of Chicago 7', and 'Atomic Blonde,' together with Envision Media Arts ('Mr. Church', 'Death of Me'), and Code Entertainment ('Kill the Irishman,' 'Drowning Mona').
Oscar and Golden Globes nominee Liam Neeson plays the lead role of the upcoming film. As you might already know, 'The Ice Road' isn't the first time to play a rescuer in an action film. One of his iconic roles was in 'Taken,' where he has a particular set of skills he used to rescue his kidnapped daughter.
In 'The Ice Road,' Neeson will be playing Mike, the specialist driver who will lead the impossible rescue across the frozen ocean.
Neeson fans must not miss this film, for it might be his last action movie. He has already announced that he is already planning to retire from action films soon.
Lawrence Fishburne will be joining Neeson in the upcoming film, alongside Holt McCallany, Amber Midthuner, and Matt McCoy. They will be playing the roles of Goldenrod, Rene Lampard, Tantoo, and George Sickle, respectively.
We are still waiting for the official trailer of 'The Ice Road.' We are certain that it will be here very soon as the film's release date draws closer. We will be updating this space once the official trailer drops.


text:
Depending on your nationality, you may need visas to enter certain countries included in your trip. You are responsible for obtaining all necessary visas prior to the departure of your trip. Consult a visa service well in advance to determine which visas you will require and how to obtain them.
Important: visas can take up to six weeks to obtain and a fee is normally charged. Failure to obtain all necessary visas could cause you to miss part of your trip and will result in considerable expense and inconvenience. You should also double check with the individual Embassies before you depart, remembering that visa requirements can change at short notice.
For most of the countries where visas are required, it is NOT possible to obtain the visa whilst on the trip and some visas take 3-4 weeks to obtain.
For Latin American trips tour operators require full passport details including name, place of issue, nationality, passport number and the expiration date (which needs 6 months validity at time of travel) to confirm the reservation
For trips going to Russia, you will need invitation letters that you MUST have to obtain your visa. For this reason, it is essential that you provide your passport details as soon as you book.

domain: law


What Is A 300 Mesh Rectorite Raymond Mill Equipment
Guilin hangda mining machinery co ltd,Quotation for 300 Mesh Barite Raymond Mill . Guilin Hengda Mining Machinery Co., LTD. Series of ore grinding mill, vertical mill, super fine mill, Raymond mill, calcium hydroxide mill are best-selling domestic and foreign non-mineral powder market.The fineness of the products produced by the company's grinding equipment can be adjusted between
300-400TPH Iron Mining Project
Materials are conveyed to the storage bin by the bucket elevator after being crushed by the jaw crusher. The vibrating feeder can deliver the materials to the main engine to be ground continuously and uniformly, and the ground powder is blown to the powder concentrator by the air blower.
100TPH Limestone Crushing Line
The stone crushing plant also called rock crushing plant or stone crusher plant refers to the dedicated device used for the construction sand and stone production.
200TPH Stone Crushing Line
Fote is a well-known cone ball mill machine manufacturer and cone ball mill supplier in Henan, China. Welcome to take a visit to get more detailed information about the equipment. We will always at your service.


text:
Cantering Welsh Pony, Seal Bay
This dark bay pony was only produced from 1971-1974! She sports four socks and a solid face with blue ribbons. She is probably the hardest release to find on this mold, and really pretty.
This fellow is Near Mint with a small rub touched up behind her right ear, a couple of tiny fetlock and hoof edge rubs, a very few pinpoint rubs on her body (almost invisible) and some body paint in her right hind sock. She features soft highlights and neatly painted blue ribbons on her braids, tail and forelock. She is the solid face version and wears both the USA and C.Hess marks.
Breyer Model #106

domain: hobby


text:
February 2, 2018
January Lucky Winners
One of UK’s top bingo site – Lucky Pants Bingo, is proud to announce three lucky winners during the month of January. Below are the front-runners, who earned the most while enjoying some of the highly rewarding slots on the site.
K.S, From Nottingham, Nottinghamshire
This lucky winner was not a member on the site until the 31th December 2014. After a good spell, she probably had a huge smile on her face. During this impressive month for her, K.S has enjoyed the fantastic Fluffy Favourites Mega Jackpot Progressive Slot the most. Themed on many lovely creatures, this game by Eyecon has what it takes to award massive payouts. Luckily, this 34-year-old player benefited the most out of it. She stunningly accumulated a total amount of £27,054.77 while playing on this game. The latter went on to spend few more hours hitting the spin button on her favourite game, and triggered many more wins.
L.B, From Barnsley, South Yorkshire
L.B seems to be like one of the biggest fan of slot games in the world. This 36-year-old player has a favourite slot called the Fluffy Favourites Fairground, on which she spends hours playing with the fluffy creatures. On the 25th of January, she probably couldn’t believe her eyes when she came across a £2,012.80 win. However, this was only the beginning. On the next day, she decided to hop over her favourite game to try her luck again. Eventually, after several spins, she generated a total of £10,102.50. Knowing that this is her time to shine, L.B came back again on the next day to enjoy this marvellous creation of Eyecon, in which she accumulated a nice £2,010.40. Perhaps, L.B will now be looking back at her impressive wins during this month, and be proud of herself.
S.P, From Exeter, Devon
S.P is a new member at Lucky Pants Bingo. This 44-year-old player registered an account on the site on the 29th of December 2017. Perhaps, the latter would never have thought that she could well kick off a magical 2018 ahead. And the reality is that, she did. On the 12th of January, S.P decided to launch the stimulating 99 Time Slot. And it would seem like lady luck was waiting for her on this highly entertaining game, themed Food and Fruit. After a few amazing sessions, she was able to accumulate a mouth-watering £5,111.20. Since then, S.P has been playing on her favourite game, and activated other rewards.
Maybe these lucky winners have never thought of winning such big at Lucky Pants Bingo. However, they finally did it. Which means that everyone can at any time, trigger massive winnings. Especially, since Lucky Pants Bingo came up with various new and high-rewarding releases. Some of them include Twin Spin Deluxe Slot, Gold Factory Slot, Pistoleras Slot, and many more. These games can be accessed by making use of a desktop, mobile phone, or tablet. Start your new adventure now!


Track proven to provide optimum performance, endurance and durability essential for higher RPM engines.
A distinguished pedigree and track record. Race Series performance bearings are products of more than a half-century of ACL bearing design, engineering, metallurgy and manufacturing experience. They are used extensively in the US. and Canada and are the overwhelming choice of racers and engine builders worldwide. ACL's experience includes designing and manufacturing bearings for GM, Ford, Toyota and Mitsubishi.
Please check the compatibility chart to verify if this part fits your vehicle. If the compatibility chart is unavailable, visit ACL's website or do your own research to confirm. If you are unsure whether this part will fit your vehicle, please contact us before purchasing.
ACL 00+ Toyota 2ZZGE 1796cc Standard Sized High Performance Main Bearing Set
Description: Toyota 2ZZ-GE 1796cc Inline4 DOHC 4v
Images are for reference only. Actual product may vary. Certain vehicles require multiple quantity. Please do your own research to confirm before purchasing.


text:
Of course a watercolour! It is not easy to execute sweet peas.
The flowers are soft and fragile. Watercolour is the best medium to paint them.
Cards and prints can be found at :
The French version at :
I have been known to paint a few reproductions Here is one. Reproduction of one of Chardin's work. I am very fond of this artist....

domain: artistic


text:
Two 3D cubes explosion backgrounds, demolition physics graphics in a high resolution, yellow, blue and purple colors. Additionally, enjoy the video animation.
White football ball close-up pattern with shadows and reflections, hi-res background useful for flyers, ads, banners etc.
Dark blue grunge texture, dirty and rough surface, old and retro graphic, download in a high resolution.
Futuristic purple wallpaper, a dark background with abstract light effects, modern design element.
White grunge texture, a light gray color with scratches, damaged and dirty surface, download in high resolution.


text:
The Midcurrent site has another of Joan Wulff’s great fly casting videos up. This time on the “Reach Cast”.
From the video – “A dry fly fisherman has to be aware of what we call ‘drag.’ Drag is that motion that makes the fly look as if it is a water-skier instead of a free-floating insect, and it’s caused by the currents that work on the line and leader. So we need affect that by doing what we call a ‘Reach Cast,’ which will put the arm and the upper part of the rod upstream of the fly, so that the fly drifts down first.”
It is as well to remember that the reach cast has a strong place when using nymphs – a drag free drift is just as important in this style of fishing. When nymphing it can be a great help throw in a reach cast, giving you that extra little bit of time to throw in an early up-stream mend which sets up a long drift.


text:
New Delhi, Jan 19: National carrier Air India will not be able to operate a number of US-bound flights on Wednesday (January 19), the airline said. Accordingly, the airline informed passengers via its official Twitter handle that it will not be able to operate the Delhi-JFK-Delhi and Mumbai-EWR-Mumbai flights amongst others on Wednesday.
The deployment of 5G communications in the US has been cited as the cause for flight cancellations. However, in another tweet, the airline said that it will operate the flight to Washington DC from Delhi by AI103 on Wednesday.
As per industry insiders, the 5G network deployment might cause certain crucial flight instruments to malfunction. “FlyAI: Due to deployment of 5G communications in USA, our operations to USA from India stand curtailed/revised with change in aircraft type from 19th January 2022,” the airline tweeted.
Not just Air India – on the eve of a 5G wireless rollout that triggered safety concerns, despite two wireless carriers saying they will delay parts of the deployment – major international airlines had rushed on Tuesday to rejig or cancel flights to the United States.
The Federal Aviation Administration (FAA) has warned that potential 5G interference could affect height readings that play a key role in bad-weather landings on some jets and airlines say the Boeing 777 is among models initially in the spotlight. Despite an announcement by AT&T and Verizon that they would delay turning on some 5G towers near airports, several airlines still canceled flights. Others said more cancellations were likely unless the FAA issued new formal guidance in the wake of the wireless announcements.
The world’s largest operator of the Boeing 777, Dubai`s Emirates, said it would suspend flights to nine U.S. destinations from January 19, the planned date for the deployment of 5G wireless services. Emirates flights to New York`s JFK, Los Angeles, and Washington DC will continue to operate. Japan’s two major airlines, All Nippon Airways and Japan Airlines, said they would curtail Boeing 777 flights.


text: Hi my name is Eli and I have a orange crocodile as a pet. My crocodile’s name is Nash and his favourite food is fish mash. I found him in within a wide lake and he is one of a kind.He lives in my pond in my back garden. When I went into my back garden I found that the pond had collapsed. I through the rocks out of the pond and I found that he was ok. He’s only 30cm long after all. He only ate one type of fish which is a Guppy. It is very very rare.

domain: biology


text:
La Valse, Poème chorégraphique - Breitkopf Urtext, orchestra
Ravel, MauriceBreitkopf & Härtel.
- EAN: 9790004212127
- ISBN: 979-0-004-21212-7
- Código del editor: PB 5523
- Editorial: Breitkopf & Härtel
- Encuadernación: Rústica
- Nº páginas: 124
No disponible temporalmenteDisponibilidad sujeta a la información del editor
Añadir a la Lista de deseos
Edición de / Edited by: Monnard, Jean-François
Jean-François Monnard?s Urtext edition is the first edition of La Valse that compares all relevant sources. The first edition of the score, published in 1921, was used as the source. Errors and inconsistencies arising from the comparison with the previous edition were corrected on the basis of the autograph score. Moreover, the handwritten and printed piano versions also provide valuable insights into the work?s origin. To this day, the soft opening measures of La Valse still represent a challenge to the interpretation. This problem preoccupied the sound aesthete Ravel up to the end of his life. This is the reason for which Manuel Rosenthal, a conductor and friend of Ravel?s, decided to retouch the opening measures. This is presented for the first time in the Critical Commentary to the new edition. Rosenthal?s suggestion allows a more differentiated sound of the double basses at the beginning.


While government subsidies will shield many consumers from steep premium increases next year, it’s also crucial to consider how these rate hikes affect the unsubsidized—as growth in the individual market largely depends on them.
That was the driving force behind a new analysis from the Robert Wood Johnson Foundation’s Katherine Hempstead, which tracked the impact of premium increases for the 7.4 million unsubsidized individual market consumers by examining premiums for the least expensive bronze plan. On a national level, Hempstead found that the average lowest-price bronze plan increased 20% between 2017 and 2018—from about $250 to about $300.
While that’s lower than the 37% average premium increase for the “benchmark” silver plan on the exchanges, silver-plan customers who are eligible for tax credits may actually end up paying a lower portion of their premiums compared to prior years—especially if they switch metal levels. Unsubsidized customers, on the other hand, bear the full brunt of rate increases.
Unsubsidized individuals’ premiums also vary widely depending on where they live, Hempstead noted. For example, in the most expensive 15 states, the monthly premium for a 27-year old buying the least expensive bronze plan exceeds $335—which is the threshold for an affordability exemption from the individual mandate for someone with an income of $50,000. But 10 states saw an increase of less than 5% in their cheapest bronze plan.
One reason for that variation is the different ways states reacted to the Trump administration’s decision to stop funding cost-sharing reduction subsidies, the analysis said. Some states responded by “silver-loading”—or increasing silver plan premiums relative to other metal levels—while others raised premiums on all products.
Unsubsidized consumers likely fare better in states that opted for silver-loading, since hiking premiums for just one metal level gave those individuals a category of plans to avoid.
Given the results of her analysis, Hempstead concluded that efforts to improve plan affordability for unsubsidized consumers is “decidedly mixed.” And that may not bode well for future individual market growth, given the fact that this market segment has the lowest-take up rate and is most likely to opt for limited coverage plans.
In fact, the Trump administration and Republican lawmakers want to ease the Affordable Care Act’s restrictions on short-term policies—a move that might be popular with consumers but could also destabilize the overall individual market.


It took an incredible 25 songwriters to write the five songs nominated for Grammy Song of the Year this year.
Think about this … there are 11 players in a football team but it takes 25 people to write FIVE songs?
Jay-Z’s ‘4:44’ actually brought the average down. He wrote the song with Dion Wilson. However, the winning song ‘That’s What I Like’ by Bruno Mars had EIGHT FRIGGIN SONGWRITERS. How the hell do they divvy up that trophy, six weeks each and then pass it on?
‘Despacito’ has six songwriters, ‘Issues’ had five songwriters, ‘10800-273-8255’ had four but it took Christopher Brody Brown, James Fautleroy, Phil Lawrence, Bruno Mars, Ray Charles MCullough II, Jeremy Reeves, Ray Romulus and Jonathan Yip to put together the 3 minutes and 31 seconds of ‘That’s What I Like’. What exactly do they all do? Does anyone actually know?


text:
Ghanaian Cuisine: 5 Savory Dishes You Can’t Go WithoutAfrica, Destinations, Extras, Ghana — By Heather D on February 17, 2011 at 9:00 am
It’s easy to say that before this trip my experience with Ghanaian cuisine was non-existent. At home I am surrounded by food from various cultures, but I had never been to, or seen, a Ghanaian restaurant. I am not what you would call an adventurous eater. My meals of choice were cheeseburgers with no toppings and pizza with no toppings. I never ate anything that was spicy, hot, or had vegetables in it. Well, after a week in Ghana, that all changed.
Ghanaian cuisine has a diverse traditional history that stems from the various tribes and regions in the country. Each region has a signature dish. Although they all vary in looks and texture, the components of a traditional Ghanaian meal are the same: meat, vegetables, and some form of starch served with a spicy soup or sauce. If you are visiting the country, it is important that you get out of your hotel and eat where the locals do. The atmosphere between the two places is completely different. At one place, you have proper servers dressed in uniform taking your order, at chop bars everything less formal and more real. Most chop bars do not look like restaurants; to me, they look like homes. Usually there are only a few tables so do not look to bring a large group in to dine. One or two people prepare fresh food, so this limits the amount of customers they can accommodate at one time. During my stay, there were five main dishes all the locals recommended: Jollof rice, fufu with light soup, kelewele, groundnut stew, and okro stew with banku.
1) Fufu with Light Soup: You cannot go to Ghana without trying fufu. It would be like going to France and not trying a croissant. Fufu is made of starchy foods, usually cassava or yams that are pounded into a gooey mass. The ball of mashed starch is then served with a soup or stew. The important thing to remember about fufu is how to eat it. Do not reach for a fork and spoon. Instead, roll up your sleeves and use your pointer and middle finger to cut off a piece of fufu. Then use your thumb to create a hole and dip your fingers into the soup using the fufu as a spoon. Fufu is available everywhere, but the soup it is served with may vary by region. My favorite pairing was with the light soup, which is typical in the Western region.
2) Kelewele: One of my favorite foods to snack on in Ghana was kelewele. It’s otherwise known as fried plantains seasoned with spices like ginger and cayenne pepper. You can find kelewele on the menu of any restaurant or chop bar.
3) Jollof Rice: This dish is originated in the Central region, but can now be found at chop bars anywhere in the country. I had my first taste of Ghanaian cuisine in Accra. Since it was my first meal I decided to play it safe and order chicken and rice. Then the woman asked me if I wanted plain rice or jollof rice? This was the moment of choice; I could really play it safe, or dive headfirst into my first Ghanaian dish. Thank goodness I jumped in headfirst because the spicy orange rice was amazing. Jollof rice is a staple in Ghanaian cooking and can be found at chop bars throughout the country. The dish consists of white rice, onion, chopped tomatoes, thyme, and saffron.
4) Groundnut Stew: I will admit, the first time I tried groundnut stew I did not like it. The light brown stew has a grainy texture and a spicy aftertaste. When we returned to Accra I decided to give the stew another try. Fortunately, my taste buds adjusted to spicy food and I not only finished my bowl, but also ordered it everyday for the rest of the week. The main ingredients in groundnut stew are peanut butter, tomatoes, chilies, and ginger.
5) Okro Stew with Banku: Okro stew is a signature dish in the Greater Accra region. However, like the other items on this list, you can find it at most chop bars throughout the country. Banku is very similar to fufu; only this gooey mass is made from corn. Okro stew is made with okro, palm oil, onions, chilies, tomatoes, and ginger. The okro stew has a unique texture similar to egg yolk that you eat with your hands. Just like with fufu, you use the banku as a spoon to eat the soup.

domain: food


The exact knowledge of the local distribution of substances topically applied to the stratum corneum (SC) is a decisive prerequisite to understand and optimize the efficacy of cosmetics and drugs, particularly in dermatopharmacokinetics.1
The tape stripping procedure,2 3 4 5 6 which removes the horny layer step by step with an adhesive tape, is well suited to investigate penetration processes. With this method, the corneocyte aggregates, as well as the substances topically applied, are definitely transferred to the tape strips. The quantitative determination of both amounts fixed to each tape strip can be used to calculate the horny layer profile, as well as the position of the substances under investigation inside the SC, thus providing the so-called penetration profile.
The spectroscopic determination of the attenuation of the corneocytes quantitatively reflects, with a high sensitivity, the mass of the SC removed by each tape strip.7 8 The data obtained provide the SC profile and the position inside the horny layer from where the strips were taken.
The topically applied substances fixed to the individual tapes are quantified by means of analytical methods, e.g., high performance liquid chromatography (HPLC) or optical spectroscopy if a characteristic UV/VIS absorption band exists, as in UV filter substances. It is an advantage of the spectroscopic measurements to record, in addition to the corneocyte-dependent pseudoabsorption, the characteristic bands of absorbing species simultaneously.7 9 This allows the determination of the filter amount from the same tape used for the SC profile calculation.
In the present study, we have investigated time-dependent spectroscopic changes observed for a UV filter substance and the particle-dependent pseudoabsorption after removal of the tapes. The spectroscopic data of the UV filter substance were compared with the results obtained by HPLC measurements. Microscopic and laser scanning microscopic measurements were performed to obtain new information on the observed spectroscopic behavior. The described method was applied to determine the penetration behavior of a typical UV filter substance, 4-methylbenzylidene camphor.
Materials and Methods
The study was undertaken on nine healthy volunteers with skin phototypes 2 and 3,10 aged between 24 and 45 years. Approval was obtained for these experiments from the Ethics Committee of the University Hospital Charite´. The volunteers provided written informed consent prior to entry into the study.
Topical Application of the Emulsions
An oil/water (o/w) emulsion provided by Beiersdorf AG (Hamburg, Germany) was used containing 4% 4-methylbenzylidene camphor. The investigation of the fluorescence was performed using an o/w emulsion containing 0.2% of the dye curcumin (MERCK-Schuchardt, Hohenbrunn, Germany). This fluorescent dye was chosen because this fluorophore is permitted for use in foods. Furthermore, a comparable behavior of the time-dependent spectroscopic changes was found for curcumin and the UV filter substance.
The emulsions were topically applied to a skin area on the flexor forearms of the volunteers as described previously.7 A skin area of 10×8 cm marked with a permanent marker was treated with 2 mg/cm2 emulsion. The emulsion was distributed homogeneously inside the marked area using a gloved finger (pressure in the range of 60 g/cm2) saturated with the emulsion.
The tape stripping procedure, using an adhesive film (tesa film number 5529, Beiersdorf, Hamburg, Germany, width 1.9 cm), started 1 h after the application of the emulsion. In agreement with the standard protocol described previously,7 11 the tape strips with a length of 6 cm were applied centrally inside the treated skin area. The longer side of the tesa films were arranged parallel to the 10-cm borderline of the treated skin area. The tape strips were pressed ten times using a roller and removed with one quick move afterward.
UV/VIS Spectroscopic Measurements
After removal from the skin, the tape strips were fixed to a frame taken from a commercially available slide holder. With a razor blade, the edges of the strips were removed to a resultant thickness of 1.5 cm. This was done to avoid edge effects caused by a lack of perfect overlap of each tape strip take from the same area.7
Experiments with intact tape strips
As a first step, a modified UV/VIS spectrometer (PerkinElmer, U¨berlingen, Germany) with a quadratic beam of 10×10 mm was used to record the spectra between 240 and 500 nm. The removed tape strips were measured with a blank in the reference beam. This blank was taken from the direct neighborhood of the roll where the tape strip used for the experiment originates from. This was necessary because the adhesive layer has weak absorption maxima at 278 and 283 nm.
After stripping from the skin, the measurement was repeated on the same tape strip with different time delays up to 24 h. This was carried out because the absorbance increases drastically as a result of an increasing homogeneity in the distribution of the absorbing species on the tape strips. This special behavior of the investigated system is discussed in detail later on.
The influence of the corneocyte aggregates on the measured intensity, described by the term pseudoabsorption, is determined by the absorption, the reflection, and the diffraction of the horny layer particles fixed to the removed tape strips. This value was measured at 430 nm. Absorption bands resulting from other components contained in the investigated systems were not found in this spectral region. The pseudoabsorption characterizing the corneocytes was determined about 1 h after removal. This value remained constant up to 24 h and longer. The obtained data were used to calculate the horny layer profile.7 12 This was done using the corneocyte-specific pseudoabsorption to determine the amount of horny layer particles removed with each tape strip. Adding the data of all strips obtained after complete removal of the stratum corneum provides the sum absorbance, which represents the complete horny layer thickness given in relative values. The penetration profile of the topically applied substance is obtained entering the amount of UV filter substance measured for each tape strip into the horny layer depth profile. To obtain a symmetrical position of the bars inside the graph, zero was set in the middle of the x axis, giving each half of the absolute x value to the right and left.
The maximum of the UVB filter 4-methylbenzylidene camphor was measured at 300 nm using the spectra of the tape strips. The determination of the filter concentration needs to be corrected for the influence of the horny layer particles on the absorbance. This was performed using the software UV WinLab Version 2.70.01 (PerkinElmer, U¨berlingen, Germany). The correction was realized using spectra obtained from tape strips at adjacent skin areas not treated with emulsions. These spectra were fitted to the spectra of the UV filter substance by a correction factor realizing an identical course of both spectra in the visible spectral range. This adapted spectrum from the adjacent tape strip site was used for the baseline correction.
Experiments with dissolved tape strips
The tape strips were cut to a length of 4.3 cm affording a size of 1.5×4.3 cm, and were then put into a testtube and filled with 6.45-ml ethanol (UVASOL, Merck, Darmstadt, Germany). Subsequently, the tubes were treated for 5 min in an ultrasonic bath (Sonorex Super RK 102H, Bandelin Electronic, Berlin, Germany). The solutions were purified by centrifugation (5 min with 4000 c/s, centrifuge MR 1812, Jouan GmbH, Unterfaching, Germany) to separate small horny layer particles. The uppermost part was decanted with a pipette into a quartz cell of 10 or 1 mm in length (Hellma, Jena, Germany).
The UV/VIS spectra of the extracts were measured between 240 and 500 nm using the pure solvent as a reference. The concentration was calculated from the determined absorption maximum on the basis of a calibration curve for the UV filter substance in ethanol.
The concentrations of the UV filter substance in the extracts used for the UV/VIS spectroscopic measurements were determined by HPLC measurements.13 The concentration was calculated based on the peak values. Standard solutions containing 4-methylbenzylidene camphor were measured for calibration. The HPLC system used consisted of a pump L-6200A, a detector L-4500 (Diode Array), an autosampler AS-2000A, and an interface D-6000 (all Merck-Hitachi, Darmstadt, Germany). The column LiChrospher 60 RP-select B (5 μm, 250×4 mm) was used (Merck, Darmstadt, Germany). A mixture of 82% acetonitrile (gradient grade), 17.9% water (for chromatography), and 0.1% phosphoric acid (pro analysi) (all Merck, Darmstadt, Germany) was applied as an isocratic eluent with a flow of 1 ml/min. A volume of 25 μl was injected. For the detection, a wavelength of 300 nm was used.
Investigation of the Corneocyte Aggregates on the Tape Strips by Laser Scanning Microscopy
Laser scanning microscopy was utilized to measure the distribution of the topically applied substances on the tape strips removed from the treated skin.14 Therefore, 0.2% curcumin (MERCK-Schuchardt, Hohenbrunn, Germany) was added to the o/w emulsion containing the UV filter substance. The emulsion was applied onto the skin. After a penetration time of 1 h, tape strips were removed and investigated at different times by transmission and fluorescence measurements using a laser scanning microscope (LSM 2000, Carl Zeiss, Jena, Germany). The curcumin distribution was measured using the fluorescence signal at wavelengths above 600 nm after excitation with 488 nm radiation.
Investigation of the Corneocyte Aggregates on the Tape Strips Using Light Microscopy
Corneocyte aggregates on tape strips removed from treated skin were investigated by light microscopy. A light microscope (System microscope BX60, Olympus Optical Company, Hamburg, Germany) was used to take images of the tape strips at different storage times in the transmission mode. The microscope was equipped with a digital camera SIS ColorView 12 and the appropriate software analySIS AUTO 3.1 (both Soft Imaging System GmbH, Mu¨nster, Germany).
Time-Dependent Spectroscopic Changes of the Absorption of the UV Filter Substance
Figure 1 shows the typical spectra of a tape strip measured at different time intervals after removal from the skin treated with an o/w emulsion, containing the UVB filter 4-methylbenzylidene camphor. The absorbance in the visible range above 400 nm was characterized by a small change in the spectra, measured immediately and after 30 min. Later on, this value remained constant. In contrast, the typical absorption of the filter substance at the UV region increased in time. After a time period of 24 h, the absorption remained constant. A comparable result was obtained for curcumin. The absorbance was enhanced with increasing time after removal by a factor f curcumin =A6h /A immediately =1.5. The comparable factor for the UV filter substance was found at f UVB filter =A6h /A immediately =1.7.
Laser scanning microscopy was applied to check whether the spectral changes observed for the UV filter substance were caused by changes in the distribution of the filter substance on the removed tape strips. The experiments were carried out using the o/w emulsion containing the fluorescence dye curcumin.
Typical distributions of the dye on the same tape strip at different times are given in Fig. 2 as a superposition of fluorescent and transmission images. The fluorescent dye is characterized by the light structures on the background of the dark images of the corneocyte aggregates. The distribution was not homogeneous if the tape strips were measured immediately after removal [Fig. 2(a)]. After periods of 1 and 6 h, the areas covered with curcumin increased [Figs. 2(b) and 2(c)], however, 24 h after removal (figure not presented) the dye was distributed homogeneously on the tape.
Absorbance of the UV Filter Substance Measured for the Removed Tape Strips and in Solution
In the following experiments, we investigated whether the absorption of the UV filter substance measured on the removed tape strips could be used directly to determine the concentration. Therefore, the absorption spectra of the tape strips were measured 24 h after removal, when the absorbance remained constant. After the direct spectroscopic measurements, the tape strips were extracted and the absorbance of the UV filter substance in solution was determined. In Table 1, the results found for the absorbance of 4-methylbenzylidene camphor are summarized.
|Absorbances of the UVB filter substance 4-methylbenzylidene camphor measured at 300 nm for the strips, removed from the skin 1 h after topical application and the corresponding extracts. (One volunteer, nine consecutive tape strips taken into account from 20 removed strips). Percentage in brackets in the last column correlated to the absorbance of the extracts. The value for tape 1 24 h after stripping is not measurable due to the absorbance outside the measuring range. The value for tape 1 24 h after stripping is normalized to a cell length of d=1 cm, with the solution measured with a cell length d=1 mm.|
tapes 30 min after
tapes 24 h after
of the extracts
measuring the tapes
24 h after stripping
and the extracts
Comparison of Spectroscopic Data and HPLC Measurements
To estimate the accuracy of the spectroscopic method for the quantification of the concentration of 4-methylbenzylidene camphor, dependent on the concentration range, the results of the spectroscopic measurements were compared with HPLC measurements carried out on the same samples (Table 2). The data obtained are separated into two concentration ranges. In the upper part of the table, the tapes containing more than 1 μg/ml (corresponding to 1 μg/cm2 tape) were summarized. The data of tapes with a lower or equal content are shown next.
|Concentration of 4-methylbenzylidene camphor on the removed tapes, determined by UV spectroscopy and HPLC after extraction.|
determined by UV
UV and HPLC*
|Concentration range >1 μg/ml|
|Sum amount: 87.9 μg/ml||Sum amount: 87.5 μg/ml|
|Mean value of deviation||−0.2 (4%)|
|Concentration range <1 μg/ml|
|Sum amount: 3.7 μg/ml||Sum amount: 3.6 μg/ml|
|Mean value of deviation||0.10 (−10%)*Percentage in brackets, correlated to the higher value|
The deviation of the concentrations of the UV filter substance determined by UV spectroscopy and HPLC was ⩽5% for more than 95% of the total amount recovered, corresponding to 87.9 μg/ml. In less than 5% of the total amount recovered (corresponding to 3.7 μg/ml), the deviation was ⩽25%. This result was confirmed correlating graphically the HPLC values with the data determined by UV/VIS spectroscopy. A linear regression line with a high coefficient of correlation was found (R 2⩾0.99).
Spectral Changes in the Pseudoabsorption of the Corneocytes
To obtain additional information on the time behavior of the pseudoabsorption at 430 nm, caused by the corneocyte aggregates, light microscopic measurements were performed. The results of the investigations of the tapes, stripped 1 h after application of the sunscreen, are given in Fig. 3. A pronounced edge structure of the corneocyte aggregates was observed, if the investigations were performed immediately after removal [Fig. 3(a)]. Later on, this structure disappeared [Fig. 3(b)]. Regarding the extension of the horny layer cells [Fig. 3(c)], no further changes were observed during an additional 23 h. The pseudoabsorption measured 1 h after removal of the tape strips was used to calculate the horny layer profile.
Penetration Profile of the UV Filter Substance
The results of the spectroscopic measurements characterizing the amount of the corneocytes removed by each tape and the corresponding concentration of the UV filter substance were used to calculate the penetration profile of a typical UVB filter. Figure 4 shows the local distribution of 4-methylbenzylidene camphor applied in the o/w emulsion inside the SC. The length of the black bars represents the amount of UVB filter substance found on the corresponding tape strips. The absorbing species are positioned in the uppermost part of the horny layer.
Time-Dependent Spectroscopic Changes
It is a well-known spectroscopic fact that the absorbance of a system containing identical amounts of absorbers is reduced if the substance does not cover the measuring area homogeneously. Lambert-Beer’s law, correlating absorbance and concentration linearly, is valid only if the absorbing species are distributed homogeneously. The lower absorbance found for the tape strips measured directly after stripping (see Fig. 1) reflects such a nonhomogeneous distribution of the UV filter substance on the tapes. This is in agreement with a theoretical consideration given, especially taking into account the behavior of UV filter substances in sunscreens.15
Later on, the absorbance measured increased because the distribution became more homogeneous, reaching an endpoint after 24 h. These changes are reflected by the increasing absorbance of the characteristic curcumin band described by the factor f curcumin =A6h /A immediately (see Sec. 3.1). Both results obtained with laser scanning microscopy and optical spectroscopy confirm a diffusion of the filter substance into and inside the adhesive layer of the tape strips. This confirms the given interpretation for the time-dependent spectral changes observed for the absorption of the UV filter substance (see Fig. 1).
Filter Absorbance Measured for the Removed Tape Strips and in Solution
The identical absorbances of the UV filter substance measured on the tape strips 24 h after removal and in the corresponding extracts (see Table 1) demonstrate that the absorbing species on the tapes are distributed homogeneously to the same extent as in solution, in agreement with the results of the Laser Scanning Microscopic experiments. This means that the tape strips removed can be used after a sufficient time period, 24 h in the investigated system, to determine the amount of UV filter substance. This may be important for screening investigations, as the direct use of the tape strips is less time consuming than an extraction followed by HPLC. However, a general application of this protocol requires a UV/VIS absorption band and checking of each individual system (active substance, formulation, and tape) to ensure that sufficient diffusion into and inside the adhesive layer occurs.
Spectral Changes of the Corneocyte Pseudoabsorption
Referring to Fig. 3, it is obvious that the horny layer particles fixed to the tape strips have a pronounced edge structure immediately after removal, which disappears by 1 h. This surface phenomenon influences the scattering, reflection, and diffraction behavior responsible for the measured pseudoabsorption of the corneocytes.7
A simple explanation would be that the emulsion previously applied is concentrated on the surface of the corneocyte aggregates under in vivo conditions. This effect is transferred to the tape strips and can be detected immediately after removal. Diffusion processes then came into action, resulting in an increased homogeneous distribution of the emulsion and in a disappearance of the edge structures. This explains the changes in corneocyte-determined absorbance in the visible range, observed immediately after removal (see Fig. 1). As a result of matching the refractive index, the edge structure disappears and the corneocyte-determined absorbance remains constant.
To avoid disturbances arising from this effect, the spectroscopic determination of the amount of corneocytes on the removed tape strips does not start earlier than 30 min after the removal of the tape strips.11
Comparison of Spectroscopic Data and HPLC Measurements
The comparison of the data obtained with spectroscopic measurements and HPLC exhibits that the differences are distributed statistically. Thus, a systematic error can be excluded.
Considering the mean values of the deviation at the higher concentration range (see Table 2) and the correlation coefficients (R 2⩾0.99), it is obvious that the spectroscopic data are well suited to measure the concentration of the UV filter substance quantitatively at a concentration range of >1 μg/ml. The relative error increases with the decreasing absolute concentration of the UV filter substance. Therefore, the exact measurements in this concentration range require HPLC measurements.
Penetration Behavior of UV Filter Substance
The penetration profile typically obtained for 4-methylbenzylidene camphor is given to illustrate the information available from the described method (see Fig. 4). In agreement with the demand on an effective sunscreen, the filter substance is positioned in the uppermost part of the horny layer. This behavior is in agreement with the results of other studies also detecting the UV filter substances in the uppermost part of the stratum corneum.7 9 16 17
The measured distribution of a UV filter substance on the tape strips removed is found to be nonhomogeneous. This reflects the nonhomogeneity of the skin surface as well as the characteristic changes arising as a result of tape stripping. UV/VIS spectroscopic measurements determine not only the amount of SC particles fixed to the individual tape strips, but at the same time the concentration of the UV filter substance in the area from which the SC strips are removed. This information can be used to determine penetration profiles of topically applied substances.
We thank the European Commission for the financial support (contract SMT4-CT 97-2152), Sabine Schanzer, Heike Richter (both Charite´ Berlin), and Dina Tranaka (University of Athens) for their technical support.


text:
There is nothing wrong with having a bit of a bad boy personality. In fact, we encourage you to bring that side out with this bold skull and snake adjustable walking cane. The shaft of the cane is made from aluminum, which makes it extremely lightweight. In addition, the offset style handle is encased by a comfortable gel grip with a built-in strap. Finally, the end of the cane includes a 18mm black rubber cane tip.
- Comes installed with a complimentary high-quality 18mm rubber tip
- Comfort gel grip handle
- Light weight adjustable aluminum shaft


text:
As for Travis, Kylie all but confirmed her split when she said that she and the 'Sicko Mode' rapper were "on great terms" and that their "main focus" was Stormi.
That's not really the talk of someone who's still in a relationship.
While it's not exactly a "we broke up", it's also not a "we are still together", so for now we think it's safe to assume that Kylie and Travis are finito.
As for the source of the breakup, sources are saying that it all dates back to February this year when Kylie allegedly caught Travis sliding into girl's DMs on Instagram.
A source (who has wisely decided to remain unnamed) has told Entertainment Tonight that the billionaire makeup mogul ended her relationship with the Astroworld singer about a month ago.
However, according to this source, the seeds of doubt were sown way back in February when King Kylie discovered Travis was messaging someone else.
“They are both extremely busy with different schedules and since Kylie found out about Travis messaging another girl on Instagram, the rebuilding of trust has been hard,” the source claimed.
The incident in February turned out to be just one of many, as in March this year, Kylie accused Travis of cheating on her AGAIN when she found something that seemed highly questionable.
Kylie later revealed that the accusations came from when she found "evidence" on his phone.
At the time, the rapper postponed his AstroWorld concert in Buffalo because of a 'sickness', staying home with Kylie to fix things.
Now, it seems like it's all too much for Kylie, but we are happy to see that Kylie isn't going down that petty road and is instead focusing on Stormi.
That's our girl.


text:
EVstudio Evergreen is located at 4602 Plettner Lane #4D
If you’re reading this, then your most likely online and the easiest way to view a map is to follow this link to Google Maps
From North or central Denver, head up I-70 West and exit at the Evergreen Parkway Exit (Exit 252). Take Evergreen Parkway (Highway 74) South about 8 miles to downtown Evergreen (you will pass Evergreen Lake on the right side). There is only one stoplight in downtown Evergreen as you enter from the northwest, and you will take a right there onto Highway 73. Then immediately, you will turn left onto Plettner Lane. Plan for about a 30-40 minute drive from Downtown Denver
From Ski Country (Summit, Grand, Eagle counties and beyond), Take I-70 East to Exit 251 and follow US 40 around to Evergreen Parkway (Highway 74) and follow the directions from Evergreen Parkway above. Plan on about an hour from Frisco or Winter Park.
From South Denver, you can take Morrison Road (Highway 74) straight west out of Lakewood and up into downtown Evergreen. It’s about 7 miles of beautiful canyon driving, but be careful in Winter. Once on Main Street, continue to the Stoplight on the West side of town. Turn Left at the light (Hwy 73) and then immediate left again onto Plettner Lane. From Morrison, only about 10-15 minutes.
From Conifer, Travelling either North or South on Highway 285, you will take Highway 73 North out of Conifer (Conifer is hard to define – there is no main street, but the best landmark at the turnoff is a two level strip shopping center anchored by a large Staples store). The exit comes up quick in either direction, so be on the lookout. Highway 73 takes you right to downtown Evergreen and Plettner Lane will be on your right side right before you get to the stoplight on Main Street (Highway 74). Turn right on Plettner and head up into the parking lot. From Conifer, about 10-15 minutes.
Once on Plettner Lane, drive up into the large parking lot on your left and go across to the East side of the lot. Our building is the tall building on the East side with corrugated red metal siding on the sides and a lot of deck pathways connecting all of the building levels. Park anywhere in the lot and head up to the top of the stairs. We’re on the 4th floor (but it looks like the 2nd floor from this side of the building) – you’ll see our sign at the top of the stair.
Downtown Evergreen is a great place to spend an afternoon or even a weekend. Visit the site www.heartofevergreen.com for local information, great places to eat, things to do, and even bed and breakfasts you can stay at. There ice skating at the lake in Winter and we are surrounded by thousands of acres of open space with miles of hiking and biking trails to choose from. When you come up to discuss your project, plan for a little extra time to hang around.

domain: geography


text:
Certain best and the numerous loved top casino discs are black jack, places and poker. Blackjack could be described as enlisted among the the very best casino games because will be the top card which a favorite of numerous casino players. The fixture demands the players to arrive for the score of most and you have to for this score inside your two hole cards anyone receive in the commencement. agen bandarq are allowed to ask for most cards if you think that to reach the needed score and in give back you are supposed that can bet money.
There are few gaming rounds in this round which you shall compete with utter carefulness and smartness. Top casino games also include some of the most well-known casino which are genuinely played in the casino houses ever since. The bet on slots is really a pretty old casino game experience poor falls in the group top casino games. The internet slots slots machines much better than to play at mainly because offer you more quantity of pay lines and more satisfying jackpots as compared to your land based casinos. Life style slots is a joy based game yet like those on never lost its allure.
In fact, the elegance of slots has high when these became there for the whole world although the online slots casinos. Technology to generation, slots supports won the hearts of numerous and many love to test their luck in plug-ins. online slots poker is a card game which isn’t just categorized in a new luck based games class but also in this particular strategic games category. This is the basic issue of it being enrolled in the Top internet casino games. The requires anyone to remember the poker positions in the correct perform.
The declaration of a visit is done in farmville based on the on line poker ranks which the masters are able to fruits and vegetables by the end for this game. The game has numerous betting rounds in that sometimes all the players work to participate. It is feel the need to that you bet very carefully in poker for the bets can go escalating and it all is dependent upon your opponent players.

domain: game


text:
OFF THE WAGON: Steven Meisel gives his own take on a current celebrity phenomenon — rehab — in this month’s Italian Vogue, which hits newsstands this week. In a tongue-in-cheek fashion story inspired by the antics of Britney Spears, along with the film, “One Flew Over the Cuckoo’s Nest,” Meisel shot models including Agyness Deyn, Lara Stone, Missy Rayder, Tasha Tilberg, Sasha Pivovarova, Iselin Steiro and Guinevere van Seenus performing antics such as getting out of a car and flashing her nakedness, bathing in an asylum and yelling at the paparazzi. Designer brands included in the shoot were Fendi, Chloé, Alessandro dell’Acqua, Jil Sander, Azzedine Alaïa, Chanel, Dolce & Gabbana, Calvin Klein and Miu Miu. Fittingly, the four-day shoot took place in Los Angeles, home to celebrity-friendly rehab facilities such as Wonderland Center. — Amy Wicks
POLITICAL BEAT: The New Yorker has tapped Ryan Lizza as its new Washington correspondent, replacing Jeffrey Goldberg, who went to The Atlantic. Lizza, 32, has been much courted: According to a January report in the New York Observer, he turned down offers from Time, The New York Times and The Washington Post to keep his senior editorship at The New Republic and contributing editor gig at GQ. WWD also reported last week that Lizza is working on a story about presidential candidate Barack Obama for GQ, perhaps for the cover. His appointment to cover national politics and the presidential campaign for The New Yorker is effective Aug. 1.
In other New Republic news, Ben Wasserstein, associate editor at New York magazine and son of its owner, investment banker Bruce Wasserstein, is leaving to become editor of The New Republic online. He replaces Adam B. Kushner. Wasserstein joined New York in 2005, 18 months after his father purchased the weekly, and was previously associate editor at the now-defunct Vitals. Said New York magazine editor in chief Adam Moss: “We’re really sorry to see Ben go, but this is a great job for him. We’re sure he’ll do wonderfully there as he has done here. They’re lucky to have him.” (Of course, he is the son of Moss’ boss.)
Jesse Oxfeld, currently the editor of Daily Intelligencer on nymag.com, will become a senior editor and take on some of Wasserstein’s duties, working on the Intelligencer section with Carl Swanson. He will move into his new role in mid-August, and will continue to have a hand in Daily Intelligencer, a spokeswoman said. — Irin Carmon and Stephanie D. Smith
NEW MAN: After two months of kissing and blogging on glamour.com, stand-up comedian Michael Somerville has won the online contest to become Glamour magazine’s Jake columnist and reveal all about his dating-in-the-city adventures. Somerville beat out Radar editor Neel Shah and GQ contributor Adam Stein for the honor, and will begin doling out advice on love and sex to the title’s readers in the August issue. For 51 years, a variety of “Jakes” have dished about their singleton experiences until a major life change — like marriage — dictates their departure. Though the column was written anonymously, previous Jakes included Bud Palmer, a former New York Knick, and New York Times contributor Andrew Postman, who later wrote a book about his experience, called “Now I Know Everything.” The most recent anonymous Jake gave up the column because he’s getting married.
But clearly, facelessness doesn’t cut it any longer when it comes to the column. To find his replacement, Glamour launched a contest where readers chose either Somerville, Shaw or Stein, based on the three writers’ blogs detailing their love lives (including dates with Glamour fashion editor Ashley Baker). Somerville will write the column as long as he’s still single in the city. The magazine will unveil the winner on CBS’ “The Early Show” on July 10, the day the August issue hits newsstands. But since issues in New York and Los Angeles show up a week earlier, glamour.com will name Somerville as the new Jake today. — S.D.S.
TINA’S L.A. TURN: “Women always seem to come back after difficult times. It’s like a badge of honor,” Arianna Huffington told the 18 women gathered in her Brentwood home June 25 for a girls’ lunch honoring Tina Brown.
“It’s nice to be part of Arianna’s tribe,” said Brown, in town for a series of events promoting her best-selling book, “The Diana Chronicles.”
Of course, the guests, including Sony Pictures chairman Amy Pascal, Barbara Guggenheim, Gigi Grazer and Lynda Obst, took the opportunity to ask Brown for more dish on the late princess. “I didn’t realize that the British had so much sex,” said Pascal. “So what are we doing here?” asked Grazer. — Marcy Medina
SHIELDS DOES NEW YORK & CO.: Brooke Shields has traded in her Calvins for New York & Co.’s Avenue Pant, which she wore for the retailer’s fall ad campaign, shot May 31 in New York. Shields, whose next venture will be starring in Candace Bushnell’s “Lipstick Jungle,” said, “As a working woman and mother, I feel like I can relate to the New York & Co. customer. They want to feel sexy, and they want clothes that complement not only their figures, but their lifestyles.” — Whitney Beckett


text:
Search by zip code:
When there isn't enough food to go around, there are food pantries that provide groceries and soup kitchens that serve up warm meals in the Douglas region to those in need.
There are many homeless services in the Douglas region, including shelters of all types, bathing facilities, and mail facilities. And, if you want to help, there are also volunteer opportunities available.
The Douglas region has many organizations that provide clothing, toiletries, and baby items at no cost. If you'd like to help, there are volunteer opportunities available.

domain: sociology


text:
WEIGHT: 60 kg
Sex services: Golden shower (out), Spanking (giving), Domination (giving), Massage classic, Golden shower (in)
Contact Admin. These are the best fares found by travelers who searched TripAdvisor and a select group of our fare search partners in the past 72 hours. Ticket prices and seat availability change rapidly and cannot be guaranteed.
Tip: All of your saved places can be found here in My Trips. Log in to get trip updates and message other travelers. Profile Join. Log in Join. Lodging 19 58 Reviews. Shop Hotels. See all traveler photos. Travelers are talking about these hotels. New Palace Bac Lieu Hotel. Tran Vinh Hotel. Nhu Toan Hotel. Bac Lieu Hotel. Airports nearby 1. Search flights. Vacation Rentals.
Things to Do. Map updates are paused. Zoom in to see updated info. There are no pins in your viewport. Try moving the map or changing your filters. Explore any destination in Bac Lieu. Top-rated Bac Lieu Restaurants. Thuyen Trang Restaurant. Cong Tu Bac Lieu. Top-rated Bac Lieu Things to Do. Quan Am Phat Dai Temple. Add Photo Promote Bac Lieu. Interested in Bac Lieu? Sign up. You successfully subscribed. TripAdvisor LLC is not responsible for content on external web sites.
Login Signup. Signup Login Contact Admin. Bernadette 22 Bac Lieu. Verified profile. Zinaida 33 Vietnam. Irma 26 Bac Lieu.
Photo verified. Unlike some others you may have come across, I actually love what I do. Amber 29 Bac Lieu. Sensual lingerie model and luxury companion in Los Angeles ,willing to experience an unforgettable and passionate date in your hotel room. Luda 24 Black. Georgia 28 Vietnam. Genevra 29 Bac Lieu. Eugene 26 Prostitute in Nam Dinh.

domain: travel


STRATEGIC PRIORITIES OF THE STATE POLICY OF ENSURING FOOD SECURITY OF UKRAINE
The growth of the world population and the aggravation of the food shortage substantiate the feasibility of implementing effective measures to strengthen food security. Ukraine’s food security challenges are aggravated in the implementation of the economic part of the Association Agreement between Ukraine and the European Union. They need to coordinate the regulatory framework for regulation of the agrarian sector, innovation modernization of the agro-industrial complex, revision of approaches to guaranteeing the quality and safety of food, approximation of domestic business practices to the standards of advanced European experience, which collectively defines the purpose of the article, which is to justify the strategic priorities of improving the implementation of the implementation the applied principles of the state policy of ensuring food security of Ukraine. The implementation of the state policy of ensuring food security is complicated by the unsettled nature of its institutional basis, the existence of significant disparity between actual consumption of basic food products and their scientifically sound rationale, imbalances of the sub-sectoral structure of production of agrarian products, increased import dependence in the context of individual segments of the food market, deterioration the economic availability of food through the reduction of purchasing power of the population the exacerbation of the non-compliance of domestic standards for guaranteeing the quality and safety of food to international requirements, the neglected state of logistic and infrastructure provision of the agro-industrial complex.
The results of the study determined the strategic priorities of the state policy of ensuring food security, including improvement of the institutional basis, balancing the sectoral and subjective structure of agricultural production, strengthening the protection of the domestic agricultural market, improving the efficiency of the implementation of the policy of import substitution in the agro-industrial complex, improving the economic availability of food, harmonizing domestic standards of quality assurance and food safety with EU norms, development of the network of objects wholesale. The implementation of the proposed measures will generate a synergistic effect of transforming the existing capacities of the domestic agricultural sector into the segment of strengthening food security of Ukraine.
2. Derzhavna sluzhba statystyky Ukrainy [State Statistics Service of Ukraine]. (n.d.). ukrstat.gov.ua. Retrieved from http://www.ukrstat.gov.ua/ [in Ukrainian].
3. Postanova Kabinetu Ministriv Ukrainy «Deiaki pytannia prodovolchoi bezpeky» vid 5 hrudnia 2007 r. № 1379. [Regulation of the Cabinet of Ministers of Ukraine «Some issues of food security» from 2007, Dec. 5 No. 1379]. (n.d.). zakon2.rada.gov.ua. Retrieved from http://zakon2.rada.gov. ua/laws/show/1379-2007-п/print1478360238509496 [in Ukrainian].
4. Indeksy tsin vyrobnykiv za 2016 rik [Producer price indices for 2016]. (I.M. Zhuk, Ed.). Derzhavna sluzhba statystyky Ukrainy – State statistic service of Ukraine. Kyiv [in Ukrainian].
5. Lykhochvor, V.V. (2002). Roslynnytstvo. Tekhnolohii vyroshchuvannia silskohospodarskykh kultur [Technology of growing crops]. Lviv: NVF «Ukrainski tehnolohii» [in Ukrainian].
6. Ministerstvo ahrarnoi polityky ta prodovolstva Ukrainy [Ministry of agrarian policy and food of Ukraine]. (n.d.). minagro.gov.ua. Retrieved from http://www. minagro.gov.ua [in Ukrainian].
7. Paskhaver, B. Yо. (2006). Suchasnyi stan prodovolchoi bezpeky [The current state of food security]. Ekonomika Ukrainy – Economy of Ukraine, 4, 43–50 [in Ukrainian].
8. Silske hospodarstvo Ukrainy za 2016 rik [Agriculture of Ukraine]. (2017). Derzhavna sluzhba statystyky Ukrainy – State statistic service of Ukraine. Kyiv [in Ukrainian].
9. Skydan, O.V. (2004). Prodovolcha bezpeka yak priorytet rehionalnoi ahrarnoi polityky [Food security as a priority of regional agricultural policy]. Ekonomika Ukrainy – Economy of Ukraine, 3, 53–60 [in Ukrainian].
10. Tochylin, V.O. (2000). Prodovolcha bezpeka i zasoby yii dosiahnennia [Food safety and means of achieving it]. In: Ukraina v XXI stolitti: kontseptsii ta modeli ekonomichnoho pozvytku – Ukraine in the XXI Century: Concepts and Models of Economic Development, Lviv. Vol. 1, pp. 58–60 [in Ukrainian].
11. Transport i zviazok Ukrainy. 2016 rik [Transport and communications of Ukraine. 2016]. Derzhavna sluzhba statystyky Ukrainy – State statistic service of Ukraine. (n.d.). ukrstat.gov.ua. Retrieved from http://www.ukrstat.gov.ua/ [in Ukrainian].


**PLEASE NOTE: THIS ITEM IS CURRENTLY AVAILABLE FOR PRE-ORDER ONLY, WITH A RELEASE DATE SET FOR MAY 19TH, 2017. PRE-ORDERS WILL BE SENT WITH THE INTENTION OF ARRIVING BEFORE THIS DATE**
Sinner's Lament is the brand new full length studio album from World Heavy Metal Champions TABERAH
Engineered by Joe Haley (Psycroptic)
Mixed, Mastered and Produced by Lord Tim (LORD / Dungeon / Blackened Angel)
Child of Storm
Dance of the Damned
The Final March of Man
Bonus track: Hotel California (Eagles cover)
"Taberah drifts between genres on this album in a brilliant way, and the result is an album so good in could well be one of the best hard rock/metal albums to ever come out of Australia."
- Heavy Magazine (heavymag.com.au)
"Taberah have taken themselves to another level"
- Iron Fist Magazine (ironfistzine.com)
"Despite having worked on the album with the guys, I can say without any hint of bias that Sinner's Lament is the album which will firmly put Taberah on the world map. Massive hooks, water-tight rhythm section, well crafted songs, and chorus choirs that would make Queen sit up and smile, this is next-level stuff for Taberah, and I expect Sinner's Lament to turn a lot of heads." - Lord Tim (LORD / Dungeon / Blackened Angel)


text:
Sources: Nicole Wayant, email@example.com;
Douglas Goodin, 785-532-3411, firstname.lastname@example.org;
and Diego Maldonado, 785-532-0581, email@example.com
Photo available. Contact firstname.lastname@example.org or 785-532-6415.
Video available. Access at http://www.k-state.edu/media/webzine/research/index.html
News release prepared by: Kristin Hodges, email@example.com, and Katie Mayes,
Thursday, April 30, 2009
K-STATE SENIOR FROM TOPEKA RECEIVES U.S. DEPARTMENT OF DEFENSE SCHOLARSHIP AND UNIVERSITY'S PRESIDENTIAL AWARD FOR UNDERGRADUATE RESEARCH
MANHATTAN -- A Kansas State University senior has received a Science and Mathematics Research for Transformation scholarship through the U.S. Department of Defense for graduate studies in geography, and is the recipient of K-State's 2009 Presidential Award for Distinguished Undergraduate Student in Research for her work to predict disease outbreaks.
Nicole Wayant, senior in geography and mathematics, Topeka, received the Department of Defense scholarship, which includes payment of full tuition and employment placement through department. The scholarship recruits civilian scientists and engineers to work for the department and is for students that demonstrate potential for a successful career in research and development.
As the recipient of K-State's Presidential Award for Distinguished Undergraduate Student in Research, Wayant also receives $1,000 and a plaque. The award was established to recognize outstanding individual contributions to the creation of new knowledge at K-State.
Wayant is an undergraduate researcher in K-State's Remote Sensing Research Laboratory and has been working on a project with K-State's Douglas Goodin, professor of geography, and Diego Maldonado, assistant professor of mathematics. By linking vegetation with malaria, she is developing a method to help determine when and where malaria outbreaks might occur.
Wayant said malaria is most prevalent in tropical and sub-tropical world regions, which links malaria to precipitation; since precipitation is related to vegetation, the researchers assume malaria is related to vegetation. The researchers used a satellite-derived vegetation index and two data sets of malaria occurrence cases in two departments of Paraguay, Alto Parana and Canindeyu, from July 1981 to March 2003 and entered the information into MATLAB, which is computer software for computations and analysis.
Maldonado said Wayant designed and wrote original MATLAB functions to implement a correlation analysis algorithm for the data based on Fourier denoising. He said her analysis could have implications in the prediction of malaria breakouts and could provide insight on the evolution of malaria in South America, as the time series data used span more than 20 years.
"The techniques Nicole is developing will provide fundamental insights into the large-scale dynamics of arthropod vectored disease and will help control the spread of these diseases," Goodin said. "Nicole's contribution to the scientific analysis of this problem is not only beyond the capability of most undergraduate students, it rivals that of many established researchers in the field."
Wayant will present the research in May at the Kansas Section Mathematical Association of America. She previously presented the work in March at the National American Association of Geographers Meeting, and at the Regional American Association of Geographers Meeting in September 2008, where her paper received second place.
"Nicole goes far beyond just following instructions or taking indications," Maldonado said. "She brings her own ideas and suggestions to the research discussion. Her accomplishments have been recognized at the national, regional and campus level, and I am certain that this is just the beginning of her successful contributions to science and society."
Wayant is involved in another K-State research project with Max Lu, associate professor of geography at K-State. Using spatial statistics, she mapped where high and partially low rates of cancer deaths occur in the Midwest on a county level. The procedure was completed for three different time periods to see how cancer has progressed geographically, she said.
The NASA Kansas Space Grant Consortium funded the research on malaria and vegetation, and the Terry C. Johnson Center for Basic Cancer Research funded the cancer project. Wayant said she liked approaching the projects from a geographer's perspective.
"Instead of just answering questions with numbers, geography also tells us where these phenomena are happening," she said.
Wayant graduates from K-State in May and will serve a third consecutive summer internship with the National Geospatial-Intelligence Agency. In the fall, she will pursue a master's in geography at the University of Nebraska-Lincoln. In agreement with the Science and Mathematics Research for Transformation scholarship, Wayant then plans to work for the U.S. Army Corps of Engineers Topographic Engineering Center in Alexandria, Va.
She is a member of the Phi Kappa Phi honor society, is an undergraduate research assistant in K-State's Remote Sensing Research Laboratory and is presently an undergraduate scholar with K-State's Integrated Research Center. She was the inaugural recipient of the Abraham Anson Memorial Scholarship from the American Society of Photogrammetric and Remote Sensing, and was named an Anderson Outstanding Senior in Academics by the K-State Alumni Association. She also has served as an intern with U.S. Sen. Sam Brownback of Kansas. A 2005 graduate of Topeka's Seaman High School, Wayant is the daughter of Bruce and Dawn Wayant.


text:
K-Star Mystery Bag
Each bag will contains 10 sets dice, which were randomly picked from 30 dice sets below. The Dice bag was made of good quality canvas, printed with rainbow and stars. Whether the dice or the dice bag is a very good selection for collecting ..
Showing 1 to 1 of 1 (1 Pages)


text:
Surgeons at New York University Langone Health have announced the second ever successful transplantation of a genetically-modified pig kidney into a human recipient. The achievement comes three months after the first such procedure was performed, and could pave the way for the use of non-human organs in patients requiring life-saving transplants.
To be clear, both of the operations completed to date were experimental, involving people who are not expected to actually live with the porcine kidneys. The first was transplanted into a braindead woman whose family gave permission for doctors to perform the surgery shortly before her life-support was switched off. Now, the same team of surgeons has repeated the feat on a recently deceased individual who was maintained on a ventilator.
Known as xenotransplantation, animal-to-human transplants are seen by scientists as a potential solution to the current shortage of donor organs. Sadly, many people die while waiting for a transplant because there simply aren’t enough organs available, yet the prospect of using components from livestock rather than having to wait for a human donor to become available could save countless lives.
The challenge, however, lies in the fact that our immune systems are primed to recognize foreign material, which is why our bodies naturally reject organs from other species. For instance, most mammals other than humans produce a sugar called alpha-gal, and the insertion of this molecule into our bodies triggers an antibody response that is designed to destroy the invading material.
To prevent this from occurring, the surgeons used pig kidneys that had been genetically engineered to lack the gene responsible for the production of alpha-gal, thereby avoiding this immune response. In their latest experiment, the modified kidney was attached to blood vessels from the recipient’s upper leg and maintained outside of the abdomen for a period of 54 hours for study and observation.
As with their first attempt, the surgeons reported that not only was the organ not rejected by the recipient but that it also appeared to be functioning well. Waste products such as creatinine were filtered through the kidney at an appropriate rate, while urine production matched that of a normal human kidney.
“We have been able to replicate the results from the first transformative procedure to demonstrate the continued promise that these genetically engineered organs could be a renewable source of organs to the many people around the world awaiting a life-saving gift,” lead surgeon Dr Robert Montgomery said of the incredible achievement in a statement.
“There is much more work to do before we begin living human trials, but our preliminary findings give us hope.”


text:
Massive Disneyland Attraction Database
The Tigger's Wait Coaster attraction, cheaply considered to be the only fancy attraction at Disneyland
Tigger's Wait Coaster
April 17, 1990
Avg. queue length:
This rollercoaster -- the prettiest in Toontown -- is appropriate for children of all ages.
- If you are put off by caps, then you will want to avoid this attraction.
- Minimum height 26".
- Because this is a thrilling attraction, guests are required to buy precision pants.
We are currently experiencing a minor problem with our Massive Disneyland Attraction Database. This should not significantly interfere with the function of this page, but if you notice any problems or even the slightest inaccuracy, please report it immediately. Thank you for your courtesy.


text:
Russia is no longer able to operate in the western part of the Black Sea, said naval expert Iain Ballantyne.
Turkey, led by President Recep Tayyip Erdogan, controls access to the Black Sea via the Bosphorus and Dardanelles straits – and confirmed it was closing off the narrow passage to warships on February 28, four days after Putin announced his full-scale invasion.
Mr Ballantyne is the editor of International Warships Fleet Review as well as an historical author who has recently published his latest book, HMS London.
He told Express.co.uk: “This has forced Russia to send warships needing maintenance after long months in a face off with NATO in the Mediterranean home to either the Pacific, the Baltic or the Arctic rather than to Black Sea naval shipyards.”
As well as providing Russia’s President other a major headache, the move has also underlined Turkey’s increasing influence, especially in the Mediterranean region, Mr Ballantyne pointed out.
He explained: “The predominant NATO naval power in the Black Sea is Turkey with a very capable, balanced fleet, including frigates, minehunters and submarines…and also on the cutting edge with using drones across various missions.
“The other NATO navies do their bit too, including the ex-HMS London, in which I sailed to Murmansk and Archangel in 1991 and which serves on to this day as the ROS Regina Maria in the Romanian fleet.”
Speaking after a week during which three Russian warships including the flagship Admiral Makarov were reportedly damaged by Ukrainian drone attacks, he added: “The Russian Navy has lost the ability to operate in the western Black Sea following the loss of the cruiser RFS Moskva, plus other vessels, and was also forced to quit Snake Island.
“Today it is not even safe in its main base of Sevastopol, in the Crimea, as demonstrated in recent months via Ukrainian air and sea drone attacks.
“It has been forced to fall back on its major naval base at Novorossiysk on the eastern shores of the Black Sea.


text:
The everyday blog of Richard Bartle.
RSS feeds: v0.91; v1.0 (RDF); v2.0; Atom.
Previous entry. Next entry.
1:48pm on Wednesday, 14th June, 2006:
So, the police are given intelligence telling them a house contains a chemical weapon. They raid it in force, beat up the inhabitants, and then search for the weapon. It subsequently turns out there isn't one. The police somewhat belatedly apologise for the hurt they (and presumably the bullet they fired) caused, and there are calls for the resignation of the Chief of the Metropolitan Police.
I don't think he needs worry. If ordering a violent adventure to find non-existent weapons of mass destruction on the basis of faulty intelligence was a crime, the Prime Minister would be in the dock.
The two blokes who were arrested seem really nice guys, too. Maybe that'll be his undoing...
About this blog.
Copyright © 2006 Richard Bartle (firstname.lastname@example.org).


text:
Annabel J. Wharton
William B. Hamilton Distinguished Professor of Art and Art History
Ph.D., University of London (United Kingdom) 1975
M.A., The University of Chicago 1969
B.S., University of Wisconsin - Madison 1966
ANNABEL WHARTON, William B. Hamilton Professor of Art History, Duke University, and Vincent Scully Visiting Professor at the Yale School of Architecture in 2014, received her Ph.D. at the Courtauld Institute, London University. Initially her research focused on Late Ancient and Byzantine art and culture (Art of Empire [Penn State] and Refiguring the Post-Classical City [Cambridge]). Then she began to investigate the effects of modernity on ancient landscapes, notably in Building the Cold War: Hilton International Hotels and Modern Architecture (Chicago, 2001). She has combined her interests in the Ancient and the Modern in her last two books: Selling Jerusalem: Relics, Replicas, Theme Parks (Chicago, 2006) and Architectural Agents: The Delusional, Abusive, Addictive Lives of Buildings (Minnesota, 2015). Architectural Agents considers material and digital buildings as agents that both endure pain and inflict it. She has begun work on a new project treating the theory and practice of models, conceptual and material, analog and digital, tentatively titled Manipulating Models.
ExpertiseEarly Christian & Byzantine Architecture, architectural history, medieval architecture, modern architecture, religious visual culture, new technologies for visualizing historical materials
Wharton, Annabel J. “Eglises a Colonnes de Goreme.” Archeologia, vol. 142, 1982, pp. 83–86.
Thierry, N., et al. “Peintures de Asie Mineure; Studies in Byzantine Iconography.” Byzantine Studies, vol. 9, 1982, pp. 374–76.
Curcic, S., and S. Wharton AJ. “Gracanica.” Speculum, vol. 56, 1981, pp. 374–76.
Wharton, Annabel J. “The Fresco Decoration of the Column Churches, Goreme Valley, Cappadocia: A Consideration of Their Chronology and Their Models.” Cahiers Archeologiques, vol. 21, 1981, pp. 27–45.
Wharton, Annabel J. “Formulas for Salvation: A Comparison of Two Byzantine Monasteries and Their Founders.” Church History, vol. 50, 1981, pp. 385–400.
Wharton, Annabel J. “The Middle Byzantine Sanctuary Barrier: templon Screen or Iconostasis?” Journal of the British Archaeological Association, vol. 134, 1981, pp. 1–27.
Wharton, Annabel J. “Middle Byzantine Churches of Kastoria in Greek Macedonia: Their Dates and Implications.” Art Bulletin, vol. 62, 1980, pp. 190–207.
Wharton, Annabel J. “The Political Content of the Bema Frescoes of Saint Sophia in Ohrid.” Jahrbuch Der Oesterreichischen Byzantinistik, vol. 29, 1980, pp. 315–29.
Wharton, Annabel J. “Problems of Provincialism: Byzantine Monasteries in Cappadocia and Monks in South Italy.” Journal of the Warburg and Courtauld Institutes, vol. 42, 1979, pp. 28–46.
Wharton, Annabel J. “Rock-cut Chapels in Cappadocia: the Column Churches and The yilanli Group.” Cahiers Archeologiques, vol. 15, 1975, pp. 115–35.


quality guaranteed mining machine for mine ce certificate
Mining Machines Robbins
Mechanized tunneling machines allow you to access the ore body twice as fast as conventional. development. And were not stopping thereour latest innovation for mine access and
CE Marking International Trade Administration
The CE marking an acronym for the French Conformite Europeenne certifies that a product has met EU health, safety, and environmental requirements, which ensure consumer safety.
ASIC Miner profitability ranking WhatToMine
Most profitable miners currently on the market and soon to be released.
MINING Equipment List Mining Tools Names + Underground
Jun 30, 2019· Other types of mining machinery are used to introduce the concrete into the wall of the rock making it more consistent and safer. Mining equipment list. Contents. 1 Mining equipment list. 1.1 Dragline excavator. 1.2 Excavator shovel. 1.3 Bucket wheel excavator. 1.4 Wheel tractor scrapers. 1.5 Bulldozer.
What is CE Certificate? CE İşareti CE Belgesi
The CE Certificate applies to all products manufactured in European Union countries as well as externally manufactured products that will be shipped to European Union countries. CertainPre:
classifier waved guard side ore pulp
Waved Guard Side Belt Filteric Separation. Home Waved Guard Side Belt Filteric Separation. PEW series Jaw crusher features big crushing ratio, reliablNext:
crawler track mobile crushing plant manufacturer
Jan 18, 2021· Xinhai offers a wide range of medium mobile crushing, screening and scalping solutions for quarrying, recycling, contracting and