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Health Issues In Schnauzers
All of our dogs have been tested for over 200+ different genetic issues and all tested non affected.
We still offer an extended health guarantee that covers any genetic, hereditary, or congenital birth defects for the lifetime of your pet.
WE STRIVE TO BREED THE HEALTHIEST PUPPIES AVAILABLE!!!!
Like all breeds, there may be some health issues, like eye diseases. Some dogs face some of these health challenges in their lives, but the majority of Miniature Schnauzers are incredibly healthy dogs compared to most breeds.
Working with a responsible breeder, those wishing to own a Miniature Schnauzer can gain the education they need to know about specific health concerns within the breed.
Not all Minis will develop all of these conditions, and those who do will experience them to varying degrees of severity, but it is not uncommon for them to form at least one health condition.
In a word, Miniatures are predisposed to getting fat. High cholesterol means high levels of fat are in the bloodstream. Left untreated, this can lead to secondary conditions such as eye problems, pancreatitis, or even seizures. Feeding a healthy diet that does not contain high amounts of fat is essential.
Diabetes mellitus is a fairly common disease in dogs. Any breed can be affected. Dogs with diabetes are unable to regulate the metabolism of sugars and require daily insulin injections. It is a severe condition and one that is important to diagnose and treat as early as possible. Symptoms include increased eating, drinking, and urination, along with weight loss. Well regulated diabetic dogs today have the same life expectancy as other canines.
This condition develops when the body loses its ability to process fat. An overly fatty meal may induce an attack as indicated by vomiting, diarrhea, or a tender tummy. A lot of breeders swear that a healthy diet can prevent this.
Bladder & Kidney Stones
These can form anywhere in the urinary system. Stones are treated either medically or through surgical removal. Some people give bottled water or filtered water only because some tap water is terrible and filled with a substantial amount of minerals
Minis tend to have allergic dermatitis, in which the skin develops an itchy rash after coming into contact with any variety of substances. It's also thought that their food is the number one source of skin allergies. So feeding a grain free healthy diet is very important. This allergic reaction can cause discomfort and appear unsightly we call this (Schnauzer Bumps), but this otherwise does not interfere with health or life expectancy.
This is a genetic condition that is covered by our lifetime health guarantee. It remains constant once it has presented. Severity can range from small disturbances in the field of vision, caused by folds in the tissue of the retina, to cataract or ultimately blindness.
Progressive Retinal Atrophy
(PRA) is a genetic disease covered in your health guarantee. It is characterized by the bilateral degeneration of the retina, causing progressive vision loss culminating in blindness. All of our adults are tested for this and passed clear.
This is not the most common health issue a Mini can have, but it is one of the worst ones that can happen. That is why we cover for this health issue in our lifetime health guarantee as well.
Mini Schnauzers can have a liver disorder called portosystemic shunt (PSS). Some of the blood supply that should go to the liver goes around it instead, depriving the organ of the blood flow it needs to grow and function properly. If your friend has PSS, his liver cannot remove toxins from his bloodstream efficiently. If he develops symptoms such as stunted growth or seizures, your vet can test his blood and possibly conduct an ultrasound scan of his liver. Surgery may be needed, but in some cases, it can be treated with medication.
We cover any heart diseases that are hereditary/congenital or due to a birth defect in our lifetime health guarantee. Miniature Schnauzers are prone to multiple types of heart disease, which can occur both early and later in life. Early detection of heart disease often allows us to treat with a medication that usually prolongs your pet’s life for many years. Veterinary dental care and weight control go a long way in preventing heart disease.


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Apartment Barges: Aa Comfort and Safety Analysis
2003 (English)Student thesis
This report presents the results of a study of the comfort and safety concerning apartment barges. The most common discomforts are due to vertical and lateral accelerations and high roll angles which are thorough described. A rough risk analysis for apartment barges is performed. If a certain risk is high and it is impossible to eliminate or reduce the probabilities of occurrence, precautions to minimise the consequences are described. The iterative planning process described briefly below is used on the two example projects: Bällstaviken and Pampas Marina.
Place, publisher, year, edition, pages
2003. , 83 p.
, Master Thesis, ISSN 1651-7660 ; 0304
IdentifiersURN: urn:nbn:se:kth:diva-11035OAI: oai:DiVA.org:kth-11035DiVA: diva2:234687
Kuttenkeuler, Jakob, Professor
NR 201408042009-09-102009-09-102010-04-28Bibliographically approved

domain: literature


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Taking time out from saving the world (that may be a lie) Monts and Nuge to dispense another hour of geek nonsense on your listening doorstep.
Direct Download: GSN PODCAST: Geek Syndicate – Episode 263
- London Super Comic Con 2016
- The upcoming Star Trek TV show finds its showrunner.
- The lads give their opinion (for what that’s worth) on the upcoming Supergirl/Flash Spin off
Week that was
- Agent Carter
- X Files
- Battlestar Galactica aka ‘it’s all fun and games until to start calling your mates toasters’.
- Cash and Guns aka ‘how many different John Woo like moves can Nuge do with a fake gun and doves’.
Contact Geek Syndicate
Subscribe to GS on iTunes: http://geeksyndicate.co.uk/subscribe/
Subscribe to GS on YouTube: http://bit.ly/SubGeekSyndicate

domain: entertainment


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Starring Giacomo Rossi-Stuart, Valerio Valeri, Erika Blanc, Giana Vivaldi
Directed by Mario Bava
Distributed by Kino Lorber
The name Mario Bava conjures forth images of vivid cinematography and a sumptuous gothic atmosphere; traits that have defined his work and influenced countless filmmakers. Bava was no stranger to these elements when it came time to make Kill, Baby… Kill! (a.k.a. Operazione Paura/Operation Fear, 1966), having already produced all-time classics such as Black Sunday (1960) and Blood and Black Lace (1964) by that point. But Kill, Baby… Kill! plays like an amalgamation of all Bava had done before, concentrating his dripping atmosphere, Victorian romanticism, and stellar, often hallucinatory, camera work into one career-defining feature. Many of his most vocal celebrants, chief among them Bava biographer Tim Lucas, have lauded its spectral elements as iconic to Italian horror cinema. Bava has a rich and varied filmography, one that frequently jumps genres, but for those looking to drink deeply in his oeuvre Kill, Baby… Kill! is a fitting place to start.
In a decaying Carpathian village, a woman plunges to her death after being pursued by an unseen force. Dr. Paul Eswai (Giacomo Rossi-Stuart) is sent to perform her autopsy. The locals, however, are a superstitious lot and they believe the woman was done in by the ghost of a young girl who haunts the village. Despite some resistance, Dr. Eswai completes his autopsy, finding a silver coin embedded in the heart of the woman. Later, he learns the story of the supposed spook: Melissa Graps (Valerio Valeri), daughter of Baroness Graps (Giana Vivaldi), who died at a young age and continues to roam the cobblestone streets, killing all she meets. While in town Paul meets Monica (Erika Blanc), a young woman who has returned to visit the grave of her parents. Later, Nadienne (Micaela Esdra), daughter of the local innkeepers, is visited by Melissa but Ruth (Fabienne Dali), a witch, reverses the curse to prevent certain death… for a while. Paul, meanwhile, comes across two gravediggers attempting to bury the body of Inspector Kruger, with whom he was to meet that same night regarding a bit of crucial information.
Eventually, it comes to the light that Melissa is the daughter of Baroness Graps and, furthermore, Monica’s parents were servants in the Graps homestead. Karl (Luciano Catenacci), the town burgomeister, attempts to prove these claims with documentation but, wouldn’t you know it, Melissa kills him before the paperwork can be produced. No one else in town is willing to assist Paul and Monica so they take their suspicions to the Baroness herself, who concedes her role in the town slayings stems from an incident many years back in which Melissa was killed due to sheer negligence on the part of the townspeople. But that isn’t the only revelation to come from the Baroness’ confession, and Paul & Monica’s long night of torment won’t end until someone is laid to rest.
Bava had only been out of the gothic horror game for a few years before he produced this film, and it’s clear the Master of Atmosphere didn’t lose a step in that time. Viewers can consider the story secondary to the austere, gloomy Carpathian environment, which is so sumptuous that drinking it in becomes compulsory. When I think of horror, in maybe a more “classic” sense, the aesthetic Bava achieves here is that concept brought to motion. It isn’t just the atmosphere, but also in the camera angles and framing where Bava gives his film an E.C. Comics feel. The scene where Dr. Eswai comes across a duo of grimy gravediggers might as well have been ripped straight from a splash page in Tales from the Crypt. Much of that sensation can also be attributed to Bava’s love of lush colors, which permeate the earthen environments like a mastered brushstroke.
Adding the necessary accoutrements of romance and haunting regality is composer Carlo Rustichelli’s classical score. Rustichelli had previously provided the soundscape to The Whip and the Body (1963), another one of Bava’s celebrated gothic romances. Although Bava had the great fortune of working with some of Italy’s top film composers – luminaries like Ennio Morricone and Stelvio Cipriani – the music provided by Rustichelli replays in my head most frequently because it perfectly complements the atmosphere Bava sought to achieve. Kill, Baby… Kill! is like a baroque painting come to life, fully immersing viewers in a strange and mystical place.
Kino says this release is sourced from a new 2K scan taken from 35mm film elements, but the results of this 1.85:1 1080p image are less satisfactory than Arrow’s recent U.K. release. For one thing, there is a slight push toward green over the picture. This skews the colors and gives the image a slight malaise. Contrast is acceptable but hardly solid. There is a pronounced softness to many scenes, with fine detail lacking throughout. A few moments near the climax show a distinct shift in quality, too. While this is by no means a bad image it doesn’t appear less faithful and defined than the region-free Arrow edition.
Both English and Italian audio are included, though the former sports an LPCM 2.0 mono track while the latter has to settle for lossy Dolby Digital 2.0 mono. The Italian track sounds slightly muffled and has less presence (surprise), while the English dub is more robust and has a less cramped feel. Rustichelli’s score sounds much better in lossless, making the English track a clear winner. Subtitles are available in English.
Former “Video Watchdog” editor and Bava biographer Tim Lucas provides an expectedly scholarly audio commentary track.
“Kill, Bava, Kill!” is a 2007 featurette with Lamberto Bava, son of Mario, discussing his family and visiting some of the filming locations seen here.
An international theatrical trailer and “German Opening Title Sequence” (which looks very rough) are also included, along with “Interview with Erika Blanc”, and a trio of hilarious American TV spots. Seriously, if you watch any bonus feature on this disc make it that one.
- BRAND NEW HD MASTER
- Audio commentary by Tim Lucas, author of Mario Bava: All the Colors of the Dark
- English-language soundtrack
- Italian-language soundtrack
- Optional English subtitles
- “Kill, Bava…Kill!” (a 2007 documentary by David Gregory, in which Lamberto Bava revisits the location where the film was shot, 25:02)
- Theatrical trailer (2:32)
- Three TV Spots (:60 :30 :10)
- German title sequence (3:30)
Desolation Review: Campers + Lunatic = Simplicity, But Not Always a Better Product
Starring Jaimi Page, Alyshia Ochse, Toby Nichols
Directed by Sam Patton
I’m usually all in when it comes to a psycho in the woods flick, but there was just something about Sam Patton’s Desolation that seemed a bit distant for me…distance…desolation – I’m sure there’s a connection in there somewhere. Either that or I’m suffering from a minor case of sleep-deprivation. Either way, make sure you’ve got your backpack stuffed, cause we’re hitting the timber-lands for this one.
The film focuses on mother and son tandem Abby and Sam, and the tragic notion that Abby’s love and father to her son, has passed away. The absence has been a crippling one, and Abby’s idea of closure is to take her adolescent offspring to the woods where her husband used to love to run and scatter his ashes as a memorial tribute. Abby invites her best friend Jenn along as emotional support, and together all three are planning on making this trip a fitting and dedicatory experience…until the mystery man shows up. Looking like a member of the Ted Kaczynski clan (The Unabomber himself), this creepy fellow seems content to simply watch the threesome, and when he ultimately decides to close the distance, it’ll be a jaunt in the forest that this close-knit group will never forget.
So there you have it – doesn’t beg a long, descriptive, bled-out dissertation – Patton tosses all of his cards on the table in plain view for the audience to scan at their leisure. While the tension is palpable at times, it’s the equivalent of watching someone stumble towards the edge of a cliff, and NEVER tumble over…for a long time – you literally watch them do the drunken two-step near the lip for what seems like an eternity. What I’m getting at is that the movie has the bells and whistles to give white-knucklers something to get amped about, yet it never all seems to come into complete focus, or allow itself to spread out in such a way that you can feel satisfied after the credits roll. If I may harp on the performance-aspect for a few, it basically broke down this way for me: both Abby and Jenn’s characters were well-displayed, making you feel as if you really were watching long-time besties at play. Sam’s character was a bit tough to swallow, as he was the sadder-than-sad kid due to his father’s absence, but JEEZ this kid was a friggin malcontented little jerk – all I can say is “role well-played, young man.”
As we get to our leading transient, kook, outsider – whatever you want to call him: he simply shaved down into a hum-drum personality – no sizzle here, folks. Truly a disappointment for someone who was hoping for an enigmatic nutbag to terrorize our not-so-merry band of backpackers – oh well, Santa isn’t always listening, I guess. Simplicity has its place and time when displaying the picture-perfect lunatic, and before everyone gets a wild hair across their ass because of what I’m saying, all this is was the wish to have THIS PARTICULAR psycho be a bit more colorful – I can still appreciate face-biters like Hannibal Lecter and those of the restrained lunacy set. Overall, Desolation is one of those films that had all the pieces meticulously set in place, like a house of cards…until that drunk friend stumbled into the table, sending everything crumbling down. A one-timer if you can’t find anything else readily available to watch.
Looking for a little direction way out in the woods? Look elsewhere, because this guide doesn’t have a whole lot to offer.
Children of the Fall Review – This Israeli Slasher Gets Political
Starring Noa Maiman, Aki Avni, Yafit Shalev, Iftach Ophir, Michael Ironside
Directed by Eitan Gafny
Reviewed out of Utopia 2017
Slashers are a subgenre of horror that are often looked down upon. After all, what can a movie about a killer slaughtering multiple people have to say about, well…anything. Those of us in the community know full well that this is nonsense and that any kind of horror movie can be a jabbing (no pun intended) commentary on society, culture, politics, art, etc… And that’s precisely what Eitan Gafny aims to do with Children of the Fall, one of the few Israeli slashers ever created.
Set on the eve of the Yom Kippur war, the film follows Rachel (Maiman), a young American woman who comes to Israel to join a kibbutz after suffering some serious personal tragedies. Her goal to make aliyah (the return of Jews to Israel) is however hampered by some rather unpleasant encounters with local IDF soldiers and members of the kibbutz. Pushing through, she makes friends with others in the commune and her Zionistic views are only strengthened, although they do not go untested. Once Yom Kippur, one of the holiest holidays in Jewish culture, begins, a killer begins picking off the kibbutz workers one by one in violent and gruesome ways.
Let’s start with what Children of the Fall gets right, okay? As slashers go, it’s actually quite beautiful. There are wonderfully expansive shots that make use of the size and diversity of the kibbutz. The film opens with a beautiful shot of a cow stable, barn, water towers, and miscellaneous outbuildings, all set against a dark and stormy night. The lighting of this scene, and throughout the film, is also very good. I found myself darting my eyes across the screen multiple times throughout the film thinking I’d seen something lurking in the shadows.
The kills, while unoriginal, are very satisfying. Each death is meaty, bloody, and doesn’t feel rushed. In fact, the camera has no problems lingering during each kill, allowing us to appreciate the practical FX and copious amounts of blood used. And if you believe that a slasher needs to have nudity, you won’t be disappointed.
The acting is middle of the road. Maiman is serviceable as Rachel but the real star of the film is Aki Avni as “Yaron”. His range of emotion is fantastic, from warm and welcoming to Rachel when she arrives to emoting grief and pain during his Yom Kippur announcement where we learn that he was a child in a concentration camp. The rest of the cast are perfectly acceptable as fodder for the killer.
So where does Children of the Fall stray? Let’s start with the most obvious part: the runtime. Clocking in at nearly two hours, that’s about 30 minutes too much. The film could easily have gone through some hefty editing without affecting the final product. Instead, we have a movie that feels elongated when unnecessary.
Additionally, the societal and political commentary is very in-your-face but the film can’t seem to make up its mind as to what it’s trying to get across. Natalia, a Belarussian kibbutz worker, raises the concept of Israeli racism, misogyny, and xenophobia, her hostility unabashedly pouring out in the midst of IDF soldiers, locals, other kibbutz members, and more. Is there validity to what she’s saying? Undoubtedly. But there is also validity to Rachel’s retorts, which include calling this woman out on her own vitriolic views. This back-and-forth mentality frustratingly prevails throughout the film, as though Gafny was unwilling to just commit.
The dialogue is also quite painful at times, although I attribute this to difficulties with translating from Hebrew to English. Even the best English speakers in Israel don’t get everything perfect and the little quirks here and there, while charming, are quite detracting. Also, why is this movie trying to tell me that Robert Smith of The Cure is a character here? While amusing, it makes absolutely no sense nor does it fit in Smith’s own timeline.
Had this film gone through a couple rounds of editing, I feel like we’d have gotten something really great. Eitan Gafny is definitely someone that we need to be watching very closely.
While Children of the Fall has a lot going for it, it has just as much working against it. Overly long, you’ll get a really great slasher that is bogged down by uneven social and political commentary.
Madam Yankelova’s Fine Literature Club Review – A Charming, Quirky Dark Drama
Starring Keren Mor, Yiftach Klein, Hana Laslo, Ania Bukstein
Directed by Guilhad Emilio Schenker
Reviewed out of Utopia 2017
One of the great joys I have in being a horror fan is seeing horror films from around the world. I view these films as a chance to learn about the fears, folklore, mythology, and lore of varied cultures. Films like Inugami, Frontier(s), [REC], and the like transport me across oceans and into places I might never get the chance to visit otherwise. Hence my interest in the Israeli dark drama Madam Yankeolva’s Fine Literature Club, the feature debut of director Guilhad Emilio Schenker.
The film follows Sophie (Mor), a member of a strange, female-only reading club – who believes that love is a lie – that we soon realize brings men into its midst only to have them killed. The woman who brings the most fitting man is awarded a trophy for her fine taste. When a member reaches 100 trophies, they get to enter a coveted and highly esteemed upper echelon of the reading club’s society, one that includes lavish surroundings and an almost regal lifestyle. Sophie starts the film earning her 99th trophy but her plans towards the all-important 100th trophy are thrown askew when she ends up developing feelings for her latest victim. She must now decide if the mission that has been so dear to her for so many years is something she wishes to see through or if she’s ready to take a huge risk and fall in love.
Now, if this seems like a strange story for a horror website, I don’t disagree. Madam Yankelova’s Fine Literature Club is certainly not your traditional horror film. In fact, I’d liken it far more to the more playful works of Tim Burton and Jean-Pierre Jeunet’s The City of Lost Children than something more grotesque and violent. It’s very playful and quite charming, although there are times when the presentation feels amateurish and certain moments when things become wildly unbelievable. That being said, the film aims to be a dark fairy tale come to life, so a healthy amount of “I’m okay letting that go” will not go unappreciated.
The film is shot in such a way that it’s very soft around the edges, almost like we’re constantly in a dream. This is aided by composer Tal Yardeni’s score, which obviously takes inspiration from Danny Elfman, playfully weaving its way through each scene.
While there’s a lot to love about Madam Yankelova’s Fine Literature Club, it’s certainly not a flawless film. As mentioned previously, there are times when it feels quite amateurish, as though no one thought to look at how a scene is being filmed and say, “People, this isn’t how things would go down. We can have fun but this just doesn’t sit right.” Additionally, the story moves very quickly. Don’t get me wrong, I’ve heard of love at first sight. But that’s not how this story plays out, so the wildly strong feelings that develop between Sophie and Yosef (Klein) seem strangely out of place.
All things being what they are, Madam Yankelova’s Fine Literature Club is a charming film that can definitely appeal to horror fans if they’re willing to stretch their boundaries to include films that have absolutely no scares or gore but imply quite a horrific situation.
Charming, quirky, but not without its faults, Madam Yankelova’s Fine Literature Club is a dark drama for fans of Tim Burton and Jean-Pierre Jeunet. Don’t go in expecting any scares or gore. Rather, anticipate a fairy tale that might be just a bit too gruesome in tone for young children.
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Tiftif2003 is an artist on Disney Create that has 100+ fans and 4600+ stars
Tiftif uses a lot of different styles like ppg, anime, and chibi styles. Although, sometimes she draws sketches or something random!
One of Tiftif's mascots is well... Tiff! She also has a mascot named Ginger. Maybe she's a leprechaun!!! XD
- Disney Create no duh
- The Interwebs Machine
- Inventing things
- Christmaz!!! Yay Christmas!!!
- Club Penguin
- Zen Gardens lol idk
- My puppy
Pictures drawn for her
If you draw one for her feel free to add it!

domain: design


text:
Linfield on red alert as Cliftonville set sights on big finish
The race for Europe continues at Windsor Park and The Oval this weekend with Cliftonville and Glenavon fighting it out to finish in third position.
With Crusaders claiming back to back Danske Bank Premiership titles, attention has switched to the European qualification scrap and relegation battles.
With only two games remaining, it's imperative that teams finish with a bang.
The Reds visit Linfield still in a state of shock from their poor display against the champions on Tuesday night with the 3-1 victory exposing defensive frailties at Solitude.
But the club is desperate to secure vital European funds to rebuild and boss Gerard Lyttle will demand his troops show some fight in their last two matches, at Linfield tomorrow and against Coleraine at the Showgrounds next weekend.
The Blues will have other ideas with boss David Healy warning: "The players are motivated and aware this is a big derby match and our record against them in recent years hasn't been good enough so we will be turning up strong and full of confidence to get the right result.
"There's huge competition for places and players also have an opportunity to put themselves in the picture for an Irish Cup Final place.
"I've a lot of time and respect for Gerard (Lyttle) and his team but it's our last home league game and we will thank the fans for their incredible support."
The Reds want to finish third and hope Linfield lift the Irish Cup, a scenario that will secure a Europa League spot.
If Glenavon win the Irish Cup or the north-Belfast side finish in fourth spot they will enter the play-offs and face the seventh placed side. The Lurgan Blues, who visit Glentoran tomorrow, are two points ahead of the Solitude men with a vastly superior goal difference. Glenavon host their Cup final rivals Linfield in their last league clash.

domain: news


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Granit Xhaka has distanced himself from an Arsenal exit saying that he’s very settled in north London.
The midfielder was one of Unai Emery’s most consistent performers last season, making 40 appearances for the Gunners.
Arsenal will once again feature in the Europa League after failing to reach the top four in the Premier League, leading to speculation that he may leave for Champions League football.
Reports have linked the Swiss international with a summer move to Inter Milan, but Xhaka says that he has no plans to leave the Emirates Stadium after signing a long-term deal.
Asked by Blick if he intends to leave Arsenal, he Xhaka said: “Not that I know.
“I have another four years contract, I only signed last year. I’m happy there, my family too. That’s the most important.”
Unai Emery will no doubt be delighted to hear of Xhaka’s commitment to the Arsenal cause, with the Gunners needing more players of his quality if they’re to challenge for the top four next term.


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Auto-Motorcycle Detailing Santa Monica
My Waterless Wash is proud to serve the Santa Monica area just as professionally as we do other customers in other locations across the Los Angeles county. We are here to serve you! .
Detailing your car or motorcycle on your day off may seem like a relaxing way to spend the weekend, but who has time for that between running errands and getting the kids to and from events? This is where keep it klean comes in! We offer full service auto and motorcycle detailing in Santa Monica California .
Rather then spending your day off cleaning your car or motorcycle why not enjoy some of the local attractions Like
2439 Wilshire Blvd., SM, CA
Douglas Park features a fly fishing area, picnic tables, tennis courts, reflecting pools, a playground, and a splash pad.
Santa Monica State Beach
1550 Pacific Coast Highway, SM, CA 90401
Why not Go to the Beach , Santa Monica State Beach is 3-miles long. Families can spend time in the sand, splash in the ocean, and go for a bike ride along the adjacent bike path. Food and beverages are available for purchase from concession stands on the beach.
Santa Monica Pier
Ocean and Colorado, SM, CA
There’s lot of things to do on Santa Monica Pier than having fun at Pacific Park. You’ll also find the historic Carousel, special seasonal activities, souvenir stands, and an arcade. If you’re hungry, the Pier also has a variety of restaurants and concession stands.
Santa Monica Pier Aquarium
1600 Ocean Front Walk, SM, CA 90401
Located on the beach, right under the Carousel on the Pier, you’ll find the Santa Monica Pier Aquarium. On exhibit are more than 100 species of marine animals, all of which are found in the Santa Monica Bay. In addition, different events are held each day the Aquarium is open. Check the website for a schedule.
3rd Street Promenade
Downtown Santa Monica
This outdoor shopping area is a popular tourist destination. Closed to vehicles, you’ll be able to leisurely stroll while you take in all the sights and sounds. You’ll find big-name stores as well as independent retail shops. A variety of restaurants, movie theaters, and street performers are on the Promenade as well.
Santa Monica Place
395 Santa Monica Place, SM, CA 90401
There’s lots to see and do at this open-air shopping center. Families will find the Disney Store, Gymboree, Nike, The Cheesecake Factory, Johnny Rockets and more. Santa Monica Place is located adjacent to the 3rd Street Promenade so it’s easy to continue your shopping experience from one location to another.
Museum of Flying
3100 Airport Ave., SM, CA 90405
the Museum of Flying you will find artifacts from the Douglas Aircraft Company, aviation-related art, a replica of the Wright Flyer, a flight simulator, and more. There is also an interactive center for children.
Auto Motorcycle Detailing
Auto’s You Get: Hand Wash, Clay Treatment ,Polish, Compound, Wax Buffing, , Scuff removal, Tires Shine, Interior Vacuum, Interior Shampoo, Windows Cleaned.
Motorcycle’s You Get: Hand Wash, Clay Treatment ,Polish, Compound, Wax Buffing, , Scuff removal, Chrome cleaning and polish.

domain: geography


You have the right to remain adorable.
A family of ducks was seen marching in a single file line outside a police station in Texas.
Video shared by the Cedar Park Police Department on Tuesday showed two adult ducks and 16 ducklings scampering down the street.
In the clip, which can be viewed above, the ducks are seen scooting along a red-painted curb near police cars in what appears to be fowl weather, under a slightly overcast sky.
“Make way!” the police department billed the video on Facebook.
The caption continued: “Cedar Park PD has 16 new recruits learning how to march in our back parking lot. Isn’t that Quacktastic?”
“#DuckDuty #QuackTheCase,” the department added on the tail end of the caption.
Facebook users loved the cute video.
“So cute!!!” one user wrote.
“CPPD always has their ducks in a row,” joked another.
One individual suggested this wasn’t atypical of the area.
“We saw some baby ducks at the pond yesterday over by Costco,” they wrote.


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Meropenem 1 gm Injection is a type of medicine that belongs to the antibiotic family. It’s used to treat severe bacterial infections. These infections can happen in different parts of your body, like the skin, soft tissues, blood, brain (meningitis), and urinary tract. Bacterial infections occur when harmful bacteria grow in your body and make you sick.
Meropenem helps by killing the bacteria that are making you sick. It stops these bacteria from building a protective wall, which they need to survive. This way, it helps you get better from the bacterial infection.
What Meropenem 1 gm Injection is Used For?
This medicine is really helpful when you have serious bacterial infections. It works for infections in various parts of your body, like complicated skin and soft tissue infections, blood infections, lung infections (including those that happen when someone is on a ventilator), and severe urinary tract infections. It can also treat infections in your brain, which are called meningitis. Meningitis is when the membranes around your brain and spinal cord get infected. Meropenem 1 gm Injection is a strong warrior against bacterial infections.
• Don’t Use If Allergic: If you know you’re allergic to Meropenem 1 gm injection or any of its ingredients, don’t use it. seizures, or epilepsy. If you see bloody and watery stools, see your doctor immediately.
• Interactions: This medicine can interact with other medicines. For example, it doesn’t mix well with some epilepsy medicines like valproic acid and divalproex sodium or with an anti-gout medicine called probenecid.
• Avoid Alcohol: While using Meropenem 1 gm injection, it’s best not to drink alcohol because it can make you feel extra drowsy and less alert.
• For Kids: This medicine is generally safe for children older than 3 months, but only a doctor should give it to them, usually in a hospital setting.
• Not Addictive: Meropenem injection is not the kind of medicine that makes you want to keep taking it. It’s not habit-forming.
Diet and Lifestyle Tips
• Avoid consuming a lot of caffeine-containing stuff like coffee, tea, energy drinks, cola, or chocolate while using Meropenem injection. This medicine might make you feel more anxious or nervous, and caffeine can add to that feeling.
• Drink plenty of water or other liquids every day while you’re using the Meropenem injection. This keeps you hydrated and helps the medicine work better.
Remember, it’s important to follow your doctor’s advice and take Meropenem 1 gm Injection exactly as prescribed to get better from your bacterial infection.
As one of the leading Meropenem 1gm Injection Manufacturers in India, Farlex Critical Care is committed to producing high-quality medications to combat severe bacterial infections. Our Meropenem 1 gm Injection is a trusted solution, providing effective treatment with careful attention to safety and quality. We prioritize patient well-being, ensuring that our products meet stringent standards. Rest assured, when you choose Farlex Critical Care, you are choosing a reliable partner in the fight against bacterial infections, backed by a commitment to excellence in healthcare.

domain: medical


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Planning for a vacation can be an exciting endeavor, filled with anticipation and the promise of unforgettable experiences. However, it’s no secret that vacations can also be costly. From airfare and accommodations to food and activities, the expenses can quickly add up. But don’t let budget constraints dampen your wanderlust. With a little creativity and discipline, you can save up for your dream vacation and make it a reality.
In this article, we will explore various strategies and tips to help you save up for a vacation without compromising on the quality of your trip. Whether you’re dreaming of a beach getaway, a city adventure, or a cultural exploration, these tips will guide you in setting a budget, cutting expenses, and generating extra income to fund your vacation fund.
Before diving into the practical ways to save, it’s important to emphasize the value of setting clear goals and envisioning your dream vacation. When you have a specific destination in mind and a timeframe for your trip, it becomes easier to stay motivated and focused on your saving efforts. So, let’s embark on this journey together, and soon enough, you’ll be on your way to that well-deserved vacation.
Setting a Vacation Budget
One of the first steps in saving for a vacation is creating a realistic budget. Setting a budget will not only give you a clear idea of how much you need to save, but it will also help you prioritize your expenses and allocate funds accordingly.
Start by determining your total budget for the trip. Consider the costs of transportation, accommodation, meals, activities, and any other expenses you anticipate. Research the average prices for these components to get an estimate of how much you need to save.
Next, break down your budget into smaller categories. Allocate specific amounts for transportation, accommodation, and daily expenses like meals and entertainment. This will allow you to keep track of how much you’re spending in each area, making it easier to stick to your budget.
It’s important to be realistic and flexible with your budget. Account for unexpected costs and leave some room for extra expenses or emergencies. Be sure to factor in currency exchange rates and potential fluctuations in prices when planning your budget.
If your budget exceeds your current financial capabilities, consider adjusting your expectations. Look for alternative accommodations, cheaper transportation options, or destinations that offer more affordable experiences.
Remember, the key is to find a balance between enjoying your vacation and staying within your means. By setting a budget and sticking to it, you’ll have a clear roadmap to guide your saving efforts and ensure a stress-free vacation experience.
When saving for a vacation, cutting expenses is a crucial step to free up extra funds. By making some adjustments to your spending habits and prioritizing your expenses, you can save a significant amount of money.
Start by taking a close look at your monthly expenses and identify areas where you can make cuts. This might include reducing spending on non-essential items such as dining out, entertainment subscriptions, or clothing purchases. Consider adopting a “needs versus wants” mentality and prioritize your spending on essential items only.
Another effective way to cut expenses is by reviewing your utility bills and finding ways to reduce them. Unplug electronic devices when not in use, switch to energy-efficient light bulbs, adjust your thermostat to conserve energy, and limit the use of appliances during peak hours. These small changes can add up to significant savings over time.
Make a grocery list before heading to the store and stick to it. Avoid impulse buying and be mindful of sales and discounts on essential items. Consider using coupons or shopping at discount stores to maximize your savings.
Transportation costs can also be minimized by carpooling, using public transportation, or even walking or biking whenever possible. Not only will this save you money, but it can also contribute to a healthier lifestyle.
Additionally, look for ways to reduce your monthly bills. Consider negotiating with service providers to secure better rates, switching to a cheaper cell phone plan or internet provider, or canceling unused subscriptions.
By being conscious of your spending habits and making smart choices, you can substantially reduce your expenses and redirect those savings towards your vacation fund.
Saving Money on Everyday Purchases
In your quest to save up for a vacation, every dollar counts. Finding ways to save on everyday purchases can significantly contribute to your vacation fund. Here are some tips to help you cut costs and maximize your savings:
- Plan your meals and cook at home: Eating out can quickly drain your wallet. By planning your meals ahead of time, creating a grocery list, and cooking from scratch, you can save a considerable amount of money. Pack your lunch for work or school instead of buying expensive meals on the go.
- Buy in bulk: Purchasing items in bulk can often lead to significant savings. Look for non-perishable items, toiletries, and cleaning supplies that you regularly use and purchase them in larger quantities. Just make sure you have enough storage space and that the items won’t go to waste.
- Utilize loyalty programs and coupons: Take advantage of loyalty programs, customer rewards, and digital coupons offered by retailers. Sign up for newsletters or apps that provide exclusive discounts and promotions.
- Shop around and compare prices: Before making a purchase, compare prices online or visit different stores to find the best deals. Don’t be afraid to negotiate prices, especially for larger items or services.
- Shop secondhand: Consider buying pre-owned items, such as clothing, furniture, and electronics, from thrift stores, online marketplaces, or garage sales. Not only will this save you money, but it can also be an eco-friendly choice.
- Avoid impulse buying: Practice self-discipline when it comes to impulse purchases. Before buying something, give yourself some time to think it over. Often, you’ll find that you don’t actually need or want the item, saving you money in the process.
- Cancel unnecessary subscriptions: Assess your subscriptions and memberships and evaluate whether you are getting value for your money. Cancel any subscriptions that you no longer use or can live without.
By implementing these strategies, you can significantly reduce your everyday expenses and allocate those savings towards your vacation budget. Remember, being mindful of your spending habits and finding creative ways to save can make a big difference in achieving your travel goals.
Utilizing Savings Accounts and Automatic Transfers
One effective way to save up for your vacation is by utilizing savings accounts and setting up automatic transfers. Here’s how you can make the most of these tools:
Start by opening a dedicated savings account specifically for your vacation fund. Look for an account that offers a competitive interest rate and minimal fees. Having a separate account helps you visually track your progress and prevents you from dipping into your savings for other expenses.
Once you have your savings account, set up automatic transfers from your checking account to your vacation fund. Determine how much you can comfortably set aside each month or each paycheck and schedule automatic transfers accordingly. This way, the money will be consistently saved without you having to remember to do it manually.
Setting up automatic transfers not only makes saving more convenient, but it also helps you stay disciplined and committed to your savings goal. Treat it as a recurring bill or expense that must be paid, and soon enough, your vacation fund will grow substantially.
If possible, choose a savings account that offers the option to round up your purchases and deposit the spare change into your vacation fund. Many banks provide this feature, and it can be a great way to save a little extra without even noticing.
Another strategy to consider is increasing the amount of automatic transfers during certain months or when you receive extra income, such as tax refunds or bonuses. By intensifying your saving efforts during these periods, you can expedite the growth of your vacation fund.
Don’t forget to regularly monitor your savings account and adjust your automatic transfers or budget if necessary. As you approach your vacation goal, you may need to make some modifications to speed up or slow down your saving rate.
Remember, consistency is key. By utilizing savings accounts and automatic transfers, you can steadily build your vacation fund and make progress towards your dream getaway.
Generating Extra Income
If you’re looking to boost your vacation savings even further, consider finding ways to generate extra income. Here are some ideas to help you increase your earning potential:
- Freelancing or side gigs: If you have a skill or expertise, consider freelancing or taking on side gigs in your spare time. This could include offering services like graphic design, writing, tutoring, or pet sitting. Websites and platforms like Upwork, Fiverr, and TaskRabbit can connect you with potential clients.
- Rent out a spare room or property: If you have a spare room or property, consider renting it out through platforms like Airbnb or VRBO. This can be a lucrative way to earn extra income, especially if you live in a desirable location or during peak travel seasons.
- Participate in online surveys or market research: Many companies are willing to pay for your opinion. Sign up for reputable online survey websites or market research panels where you can provide feedback and earn rewards or cash.
- Sell unwanted items: Declutter your home and sell items that you no longer need or use. Platforms like eBay, Facebook Marketplace, or local yard sales can help you turn your unwanted belongings into cash.
- Monetize your hobbies: Do you have a hobby or skill that could be turned into a source of income? Consider selling your handmade crafts, artwork, or homemade baked goods. Explore local markets, online marketplaces, or create your own website to showcase and sell your creations.
- Take on temporary or seasonal work: Look for temporary or seasonal job opportunities, especially during busy periods like holidays or tourist seasons. This could include retail, hospitality, or event-related positions.
Remember to clarify any legal or tax obligations associated with these income-earning activities in your area to ensure compliance.
By exploring these opportunities and finding ways to generate extra income, you can accelerate your savings and reach your vacation goal faster than expected.
Conserving Energy and Reducing Bills
Conserving energy not only helps the environment but can also lead to significant reductions in your utility bills. By implementing energy-saving strategies, you can save money that can be allocated towards your vacation fund. Here are some tips to help you conserve energy and reduce your bills:
- Unplug electronics when not in use: Many appliances and electronics continue to draw power even when they’re turned off. Unplug them or use power strips with surge protectors to easily switch off multiple devices at once.
- Switch to energy-efficient light bulbs: Replace traditional incandescent light bulbs with energy-efficient options such as LED or CFL bulbs. They last longer and consume less energy, leading to lower electricity bills.
- Use natural lighting whenever possible: Open curtains and blinds during the day to take advantage of natural sunlight. Reduce the use of artificial lighting and rely on natural lighting as much as possible.
- Set your thermostat wisely: Adjust your thermostat to conserve energy when you’re not at home or during periods when you can dress comfortably for slightly cooler or warmer temperatures. Use a programmable thermostat to automate temperature adjustments.
- Limit water usage: Take shorter showers, fix leaky faucets promptly, and consider installing water-saving devices such as low-flow showerheads and faucet aerators. These small changes can lead to substantial savings on your water bills.
- Optimize appliance usage: Run full loads when using your dishwasher, washing machine, or dryer. Avoid using these appliances during peak hours when energy prices are usually higher.
- Insulate your home: Properly insulate your home to prevent air leaks and improve energy efficiency. This can help regulate indoor temperatures and reduce the need for heating or cooling systems, resulting in lower utility bills.
- Seal windows and doors: Check for gaps and drafts around windows and doors. Seal them with weatherstripping or caulking to prevent air leakage, keeping your home more energy-efficient.
Implementing these practices will not only benefit your wallet but will also contribute to reducing your carbon footprint. Conserving energy is a win-win situation that helps both your vacation fund and the environment.
Tracking Progress and Staying Motivated
As you embark on your journey to save for your dream vacation, it’s important to track your progress and stay motivated along the way. Here are some tips to help you stay on track:
- Set specific milestones: Break down your savings goal into smaller milestones. For example, set targets for saving a certain percentage of your total goal or reaching a specific dollar amount. Celebrate each milestone to keep yourself motivated and encouraged.
- Use visual aids: Create a visual representation of your savings goal. This could be a savings thermometer or a vision board that depicts your desired destination or experiences. Display it in a prominent place as a daily reminder of what you’re working towards.
- Track your expenses: Keep a record of your expenses to monitor your spending habits. This will help you identify areas where you can make adjustments and allocate more funds towards your vacation savings.
- Utilize budgeting apps or spreadsheets: Use budgeting apps or spreadsheets to track your income, expenses, and savings progress. These tools can help you stay organized and give you a clear picture of your financial situation.
- Join online communities or support groups: Connect with others who are also saving for a vacation or have achieved their travel goals. Online communities or support groups can provide valuable advice, encouragement, and motivation throughout your saving journey.
- Reward yourself along the way: Set smaller rewards for yourself as you hit savings milestones. It could be treating yourself to a small indulgence or a special experience that aligns with your vacation goals. These rewards can provide positive reinforcement and keep you motivated to continue saving.
- Share your goals with friends and family: Share your savings goals with your loved ones. They can offer support and help hold you accountable. Additionally, they may have tips or ideas for saving money or finding travel deals.
- Visualize your future vacation: Take time to envision yourself enjoying your dream vacation. This mental imagery can fuel your motivation and remind you of the exciting experiences that await you once you reach your goal.
Remember, the journey to save for a vacation is as important as the vacation itself. Embrace the process, stay dedicated, and celebrate each step forward. With determination and perseverance, you will soon find yourself enjoying the trip of a lifetime.
Saving up for a vacation may seem like a daunting task, but with careful planning, discipline, and a bit of creativity, it is entirely achievable. By setting a budget, cutting expenses, utilizing savings accounts and automatic transfers, generating extra income, conserving energy, and tracking your progress, you can embark on your dream vacation sooner than you think.
Remember, the key is to stay motivated and focused on your goal. Celebrate your milestones along the way and visualize the incredible experiences that await you. It’s important to strike a balance between saving diligently and enjoying life, so don’t forget to reward yourself from time to time.
Whether you’re dreaming of relaxing on a tropical beach, exploring historic cities, or venturing into the great outdoors, your dream vacation is within reach. So start saving today and watch your vacation fund grow. Before you know it, you’ll be stepping off that plane, ready to create memories that will last a lifetime.
Now, go ahead and plan your budget, implement the strategies discussed, and start saving for your dream vacation. Happy travels!

domain: economics


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Discussion in 'Black Poetry - Get Your Flow On!' started by alyce, Jun 8, 2002.
thank you for coming
that was so thoughtful of you
let's do it again...
Simply beautiful. This poem is a branch which may grow into another direction at any given time, according to the reader's position. Very crafty work indeed, my sistah.
again friendship comes together for a warm gethering
alyce i saw this in a vision as i was reading u ....beautiful
waiting for the next episode.....
hmmm...i agree with joyce, alyce. quite nyce.
Separate names with a comma.

domain: artistic


For all the glory surrounding the new camera sensor, Motorola’s default camera has an unintuitive design, one that eschews functionality in favour of simplicity. For example, by default, the camera app expects you to shoot without a dedicated shutter button. A semicircular carousel can be pulled from the sides which includes all the settings, which are very few to begin with. You can switch on HDR mode, switch on the flash, choose a special night mode, trigger control of focus on or off, set a timer, shoot a panorama, and trigger Quick Capture. There are absolutely no manual settings or filters available, and what makes this worse is the fact that Motorola doesn’t allow third-party apps to use the camera API. Furthermore, by default, the control of focus and exposure setting is off and we recommend that you switch it on. Once you do that, you can achieve granular control over depth instead of focussing on the entire canvas.
The 21-megapixel camera on the Moto X Style is definitely leagues ahead of the sensors we’ve used on the previous generation Moto X devices as well as the Nexus 6. It can focus really fast and shoot faster than most mid-range phones out there. Our daylight shots, once we adjusted the focus accurately, produced some fairly accurate colours and the details in the image were intact too. Even the dynamic range was fairly good, and it managed to bring out the highlights and shadows accurately. The HDR mode wasn’t really required on most occasions, but when used in extremely bright environments the HDR mode managed to bring out subtle changes without changing the overall tonality of the original image. The camera started to struggle when we shot indoors and in low light. The noise compression algorithm starts working overtime and you start getting smudged details in indoor settings. In darker conditions though, the noise in images starts becoming fairly visible and pronounced. The F2.0 aperture doesn’t really do justice.
Out of the box, the Moto X Style shoots 1080p video, but the resolution can be bumped up to 4K. The details were really impressive and the colour accuracy was also spot on. It shoots both 4K and 1080p at 30fps and we didn’t notice any frame drops. However, since the camera lacks image stabilisation of any sort, we ended up with slightly shaky and blurred imagery often. The 720p slow-motion video was far from impressive and we’ve seen better on devices like Samsung Galaxy S6 and the iPhone 6.
On paper, the 5-megapixel front facing camera also includes an F2.0 aperture for better shots in low light, but unfortunately this didn’t translate in real life. Our test shots were quite muddy and lacked details. You need adequate light for decent looking self portraits. The flash helps bring out some of the lost details, but ends up casting a harsh light on the face. In daylight though, selfies do look impressive.


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Pancreatic tumors are notoriously hard to treat. One of the reasons is they are filled with so much pressure that blood vessels collapse and cancer-fighting drugs can’t get in. But now researchers have a better understanding of exactly what causes the pressure — and what might be done to lessen it.
The latest findings from scientists at Fred Hutchinson Cancer Research Center, published Tuesday in Biophysical Journal, confirm that a gel fluid, rather than free-flowing fluid, is what puts the squeeze on tumors. Only strategies that melt away the gel inside the tumors will relieve enough pressure to reopen the tumors’ crushed blood vessels and allow chemotherapy in, their work suggests.
“Unless you know the source [of pressure inside pancreatic tumors], you don’t know how to tackle the problem,” said Dr. Sunil Hingorani, the study’s senior author.
The work highlights the biophysics of pancreatic tumors as a novel therapeutic target, “which we think is something that has not been looked at as rigorously as it could be,” said first author Dr. Christopher DuFort, a postdoctoral researcher in Hingorani’s lab. The findings suggest that “drugs that target the biophysical properties of tumors could lead to new therapies.”
“We’ve described this in one specific example in the pancreas, but there are other tumor types that have high levels of this unique molecule [that creates the gel]. So it could be warranted to look at this in other contexts as well,” said DuFort.
The current study is an extension — and a validation — of a previous finding that startled Hingorani and his team. It was already known that pancreatic tumors turn a few truisms about cancer on their head, including the well-established notion that cancers will build a fresh new blood vessel network to meet their growing nutrient and oxygen needs. Pancreatic tumors, in contrast, don’t grow new vessels. In fact, most of the blood vessels they do have are crushed shut — a situation that blocks chemotherapy drugs from entering.
Hingorani and his group used a tool known as a piezoelectric catheter (or PC) to probe the pressures inside pancreatic tumors. To the researchers’ great surprise, the PC registered tumors’ internal pressure up to 100 mmHg. “That’s equal to the pressure the heart uses to pump blood through the entire body. It’s definitely enough to collapse capillary blood vessels,” said DuFort.
“We were shocked,” said Hingorani of the original measure. “We repeated the experiment 10 times before we got over our incredulity and accepted that this was what nature is doing.”
But accept it they did — and located the source of the pressure. In all tissues, a long sugar molecule called hyaluronic acid (or HA) grabs onto molecules of water to create a gel. In spaces like our joints, HA plus water create a shock-absorbing layer. Pancreatic cancers produce HA in very high amounts. The team concluded that the source of the pressure inside pancreatic tumors was from the HA gel that swelled as more water became trapped, shoving blood vessels shut and slamming the door on chemotherapy.
In work published in 2012, they found that when they used an enzyme to digest the HA, pressures inside pancreatic tumors plummeted as previously trapped water flowed away. Blood vessels opened — and drugs, carried by the bloodstream, sailed in.
These results led directly to a Phase 1b clinical trial of the enzyme, PEGPH20, coupled with the drug gemcitabine. An interim analysis from a randomized Phase 2 trial, performed in conjunction with the company Halozyme, which developed PEGPH20, suggests that this combination can double survival time for some pancreatic cancer patients. A Phase 3 trial has begun enrolling patients with late-stage pancreatic cancer.
Prior measures of pressure inside pancreatic tumors had detected a mild 4 or 5mmHg — not nearly enough to overcome the pressure of 15 to 40mmHg that blood exerts on vessels as it flows through. These recordings came from tools designed decades ago to measure freely flowing fluid, such as in cases of edema, when water in the spaces between cells causes limbs to swell. Because most of the fluid filling the spaces between cells within pancreatic tumors is trapped by HA as a gel, the older tools are essentially blind to the fact that pressures inside pancreatic tumors build 20 times higher than 5mmHg.
It’s critical to know exactly where pressures inside tumors are coming from, said DuFort. Historically, gel-fluid pressures have been lumped together with solid pressures, and their possible contributions to fluid pressures have been ignored. But an incorrect model of tumor pressure will lead researchers trying to relieve the pressure down paths toward ineffective drugs.
“Even if we developed a way to relieve pressure from the free fluid, that will only reduce pressures by about 5mmHg. It’s not enough to open the blood vessels,” he said. There aren’t enough collagen fibrils in direct contact with blood vessels inside tumors to explain their widespread collapse either.
So DuFort and his colleagues took a deeper dive into pancreatic tumors, carefully demonstrating that their tool did indeed detect pressures that other commonly used technologies missed — and that these pressures arise from water ensnared by HA in a gel form.
To do so, DuFort compared the PC with another instrument called the wick-in-needle, or WN, which needs the movement of free fluid to register pressure. By comparing how the PC and the WN fared when measuring pressures from pure water or HA-based gels, DuFort found that while both instruments could easily detect pressure (and increases in pressure) from pure water, only the PC registered changes in pressure when in immersed in an HA gel. The WN was nearly blind to pressures in this environment.
When the team compared readings from the two instruments in tumors, they saw that the WN measured much lower pressures than the PC. Adding PEGPH20, the enzyme that chews up HA and turns its gel back into free-flowing water, caused readings from the PC to drop — but in turn produced a slight bump in readings from the WN as it registered new pressure from the now-untethered water.
Inside pancreatic tumors, water molecules and solid structures like collagen fibers exert pressure. Pancreatic tumors have an abundance of fibers, like collagen, that can only stretch so far. Unable to ooze outward, the water tangled with HA pushes on every open structure, like blood vessels. The HA-water gel essentially acts as a bridge between both types of forces, increasing pressure throughout the tumor, the researchers said.
The potentially winning combination of an HA-chewing enzyme and an old chemotherapy came from investigations using Hingorani’s carefully developed preclinical model of pancreatic cancer that mimics the human disease. He feels that the current results present a strong argument for concentrating on such models, instead of relying on tumor grafts.
DuFort compared gel and free-fluid pressures inside grafted tumors and tumors that arose naturally in the preclinical model Hingorani developed. While tumor grafts did have higher pressures than healthy organs, the gel pressures didn’t rise to the same level as those seen in naturally occurring tumors. Instead, the tumor grafts had much higher pressures from free water than natural pancreatic tumors.
Also, tumor grafts usually have many more blood vessels and have much less fibrous material surrounding their cells — contrary to natural pancreatic cancer. Drugs will act very differently in these two environments, DuFort and Hingorani caution. The most effective drugs will be those that target features of pancreatic tumors, not tumor grafts.
Nailing down the right source of pancreatic cancer’s high pressures opens up many avenues — for research, and for optimism, said Hingorani. Other potential treatments, like gemcitabine, may have failed to overcome the disease because they failed to access the cancer cells sealed inside the tumors. Once combined with an agent like PEGPH20, which will provide this access, these drugs may actually become effective.
Other tumors, like lung cancer and breast cancer, produce higher amounts of HA than healthy tissue. Though the current work focused on pancreatic cancer, it may be that other tumors are subject to similar pressures that have also been missed — and may be a potential avenue for therapeutic development, said Hingorani.
The team is continuing to examine the pressures inside pancreatic tumors. As they move forward, Hingorani and his group will keep their minds open. “You have to let nature teach you rather than the other way around,” said Hingorani.
Sabrina Richards is a staff writer at Fred Hutchinson Cancer Research Center. She has written about scientific research and the environment for The Scientist and OnEarth Magazine. She has a Ph.D. in immunology from the University of Washington, an M.A. in journalism and an advanced certificate from the Science, Health and Environmental Reporting Program at New York University. Reach her at firstname.lastname@example.org.


Originally Posted by gunners
I used the Berger twist calculator for my Hornady 53 gr v- max it says unstable @.74 but it also says the 50 gr v- max would be unstable too @.84. Marginal stability starts at 1.0 with optimal being 1.4. Another more comprehensive calculator gives me 1.1 for my 53's. I figure if it shoots a- maxs alright it should be ok.
683 yards on a Pd is some pretty fine shooting. My barrel is probably just over a 1000 so not worth a rebarrel yet. I really want to get to the range and try them
Keep in mind that the Berger calculator is at its best with conventional jacketed hollow points. JBM Ballistics has a twist calculator that takes into account the plastic tips, which can have a big effect on the required theoretical twist. Their calculator can be found here:
JBM - Calculations - Stability
One other thing to consider is that there is a sizeable difference in length between the 52 grain AMAX and the 53 grain VMAX. The AMAX is very close in dimensions to the 50 grain VMAX. The 53 VMAX has a very aggressive nose, using the same profile as the nose on the 75 grain AMAX. It is longer, overall, than the 55 grain VMAX.


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domain: psychology


text:
This Book is in Good Condition. Clean Copy With Light Amount of Wear. 100% Guaranteed. Codice inventario libreria
Riassunto: Americans have long had a fixation with the occult. Now well-known writer and expert on the occult Mitch Horowitz presents a meticulously researched, compulsively readable history of the mystical and spiritual experience in our country. Focusing on the tremendous impact that nineteenth-century movements such as Freemasonry, Spiritualism, and Transcendentalism have had on America, Horowitz explains the origins of the Ouija board, the political influence of Spiritualism on the Senate, and the source of the mysterious slogan on the back of the dollar bill. The colorful cast of characters extends from those on the margins of documented history to famous heroes like Abraham Lincoln. Occult America will appeal to history buffs, spirituality enthusiasts, and everyone who savors fascinating narrative nonfiction.
It touched lives as disparate as those of Frederick Douglass, Franklin Roosevelt, and Mary Todd Lincoln--who once convinced her husband, Abe, to host a séance in the White House. Americans all, they were among the famous figures whose paths intertwined with the mystical and esoteric movement broadly known as the occult. Brought over from the Old World and spread throughout the New by some of the most obscure but gifted men and women of early U.S. history, this “hidden wisdom” transformed the spiritual life of the still-young nation and, through it, much of the Western world.
Yet the story of the American occult has remained largely untold. Now a leading writer on the subject of alternative spirituality brings it out of the shadows. Here is a rich, fascinating, and colorful history of a religious revolution and an epic of offbeat history.
From the meaning of the symbols on the one-dollar bill to the origins of the Ouija board, Occult America briskly sweeps from the nation’s earliest days to the birth of the New Age era and traces many people and episodes, including:
· The spirit medium who became America’s first female religious leader in 1776
· The supernatural passions that marked the career of Mormon prophet Joseph Smith
· The rural Sunday-school teacher whose clairvoyant visions instigated the dawn of the New Age
· The prominence of mind-power mysticism in the black-nationalist politics of Marcus Garvey
· The Idaho druggist whose mail-order mystical religion ranked as the eighth-largest faith in the world during the Great Depression
Here, too, are America’s homegrown religious movements, from transcendentalism to spiritualism to Christian Science to the positive-thinking philosophy that continues to exert such a powerful pull on the public today. A feast for believers in alternative spirituality, an eye-opener for anyone curious about the unknown byroads of American history, Occult America is an engaging, long-overdue portrait of one nation, under many gods, whose revolutionary influence is still being felt in every corner of the globe.Amazon Exclusive: Mitch Horowitz on the Occult in American History
Early American history is entwined with esoteric spirituality. North America’s first intentional mystical community reached its shores in the summer of 1694. That year, the determined spiritual philosopher Johannes Kelpius led about forty pilgrims out of Central Germany--a region decimated by the Thirty Years’ War--and to the banks of the Wissahickon Creek, just beyond Philadelphia. The city then hosted only about 500 houses, but it represented a Mecca of freedom for the Kelpius circle, who longed for a new homeland where they could practice their brands of astrology, alchemy, numerology, and mystical Christianity without fear of harassment from church or government.
Soon more mystical thinkers from the Rhine Valley journeyed to America, building a larger commune at Ephrata, Pennsylvania. A young woman named Ann Lee fled persecution in her native Manchester, England and relocated her esoteric sect, the "Shaking Quakers"--or the Shakers--to upstate New York in 1776. That same year, a Rhode Island girl, Jemima Wilkinson, declared herself a spirit channeler, took the name Publick Universal Friend, and began to preach across the northeast. The trend was set: America became a destination for religious idealists, especially those of a supernatural bent.
By the 1830s and 40s, a region of central New York State called "the Burned-Over District" (so-named for its religious passions) became the magnetic center for the religious radicalism sweeping the young nation. Stretching from Albany to Buffalo, it was the Mt. Sinai of American mysticism, giving birth to new religions such as Mormonism and Seventh-Day Adventism, and also to Spiritualism, mediumship, table-rapping, séances, and other occult sensations--many of which mirrored, and aided, the rise of Suffragism and related progressive movements. The nation’s occult culture gave women their first opportunity to openly serve as religious leaders--in this case as spirit mediums, seers, and channlers. America’s social and spiritual radicals were becoming joined, and the partnership would never fade.
Indeed, the robust growth of occult and mystical movements in nineteenth-century America--aided by the influence of Freemasonry and Transcendentalism--helped transform the young nation into a laboratory for religious experiment and a launching pad for the revolutions in alternative and New Age spirituality that eventually swept the globe. In the early twentieth century, the new spiritual therapies--from meditation to mind-body healing to motivational thinking--began revolutionizing how religion was understood in contemporary times: not only as a source of salvation but as a means of healing. In this sense, occult America had changed our world. --Mitch Horowitz
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Descrizione libro Blackstone Audiobooks, 2009. MP3 CD. Condizione libro: Brand New. unabridged edition. 1 pages. 7.50x5.25x0.50 inches. In Stock. Codice libro della libreria 1441711112
Descrizione libro Blackstone Audio, Inc., 2009. MP3 CD. Condizione libro: Good. Unabridged. Ships with Tracking Number! INTERNATIONAL WORLDWIDE Shipping available. May not contain Access Codes or Supplements. Buy with confidence, excellent customer service!. Codice libro della libreria 1441711112

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Dozens of homes were evacuated during the recent BC fire in Okanagan Similkameen district and a state of emergency was declared in Oliver last weekend, where Black Hills Estate is located.
‘We saw a small bit of smoke at 7:30pm and within a link of hours we thought “oh jeez”, there’s smoke appearance out of the hills now,’ Fawcett told Decanter.com. ‘We reported it to the fire benefit, but the wind picked up and within another hour there was 1,000 acres up in flames.
‘It was just growing, and appearance down the valley to vineyards and houses. It looked
Photos on social media captured the vast area of hillside on fire.
#BCWildfire #oliverfire #oliverbc view from Osoyoos, whole mountain ridge appears to be on fire. pic.chirrup.com/FzWUyVOCbb
— ! (@JamesPutnam) August 15, 2015
‘We weren’t sure whether it would cross the valley to our side, so we were packing up all of our valuables. It was absolutely terrifying – we had a front row seat.’
See also: California fires rage but vineyards safe, says Napa Vintners
Fortunately for Fawcett and many residents, the wind changed and firefighters were able to bring the fire below hegemony. Flames came to within feet of some vineyards in the Golden Mile area south of Oliver, which sits in the middle of Canada’s only official desert.
Local residents and wineries thanked firefighters on Chirrup.
Today we raise a glass to our protectors #oliverbc #oliverfire #thankfulness #bcwine pic.chirrup.com/VeWuQv8xI9
— OliverOsoyoosWine (@UncorktheSun) August 17, 2015
Smoke taint is
‘We’ve been extremely fortunate,’ Fawcett said, adding the the 2015 wine harvest looks promising after a longer than average growing season. Black Hills Estate specialises in Bordeaux blends.
A BC spokesperson told Decanter.com on Monday this week that, despite tense moments, wineries and vineyards in the area were thought to have survived unscathed.
The post BC fire: Winemaker re-lives ‘terrifying’ near miss appeared first on Decanter.
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Winchester Model 70 Black shadow
Anyone have opinons of the black shadow winchester 70's? I am looking at one locally in 30-06. I like it a little better then the regular model 70 for a few reasons. 1) synthetic stock, 2) not as pretty, and since it is a field gun, no worries about banging it up, 3) price point.
What kind of accuracy is to be expected from this rifle? Anyone have any experience with these. Good accuracy or so-so?


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MIAMI -- Often key to the outcome of presidential elections, the Interstate 4 corridor here once again could shape a primary election Tuesday for Republicans.
Undecided voters in the growth-oriented counties along the 132-mile highway played a key role in the 2004 presidential election. The highway snakes diagonally south from Tampa to Daytona Beach through the so-called "bellwether counties" of Florida, said Marcus Jadotte, who was state director for Democrat Al Gore's campaign eight years ago.
"In a statewide campaign, you cannot just win southern Florida and win the state, and the same can be said about northern Florida," said Jadotte, now public affairs director for NASCAR. "That ribbon of Florida geography is key to all of the races."
Since their South Carolina primary Jan. 19, all of the Republican candidates have traveled I-4 in search of votes. Former New York Mayor Rudy Giuliani spent two weeks here ahead of his GOP rivals, skipping other caucuses and primaries to concentrate on the Sunshine State.
"The fate of the entire Republican primary race lies in the I-4 corridor," Jadotte says. "Whoever wins those counties will win the primary."
His prediction could hold true, if history is any indication. State election records show that since 1996, six counties in central Florida -- Volusia, Orange, Pasco, Pinellas, Brevard and Hillsborough -- have picked winners in presidential elections, including in 2004 when George W. Bush won Florida. Three other counties -- Sumter, Polk and Seminole -- also went for Bush in 2004.
"I-4 voters are typically swing voters. They are not set in their ways, but nearly always determine the outcome," said Lew Oliver, chairman of the Orange County Republican Party.
"The people who live there tend to be more transient, more diverse and, typically, are from all different parts of the country."
Among Florida's 18.1 million residents, 76 percent are white, 15 percent black and 20 percent Hispanic. The state's male-female population is about evenly split. Its median age, at 39, is higher than the national median of 36. Of the 10.2 million registered voters, 3.8 million are Republicans, 4.1 million are Democrats, and the rest are spread among 28 minor parties.
In the nation's first primary earlier this month in New Hampshire, a small state with a majority of white voters, the voting bloc that swung the state wasn't registered Republicans or Democrats, but independents. That won't happen Tuesday in Florida, because state law prohibits independents from voting in primary elections.
Former Pennsylvania Gov. Tom Ridge was scheduled to campaign today in Tampa for GOP Sen. John McCain.


Philadelphia Rapper, Meek Mill, has decided to take a stand on the American Justice System, trying to reform justice, after being sent to jail for 2-4 years on November 6, 2017 for “popping a wheelie” in New York City.
The arrest and extensive prison sentence generated fans, fellow rappers and high-profile athletes, to rally and protest in Center City a few days later. Meek Mill was later granted an early release on April 24, 2018 by the state Supreme Court.
He has since teamed up with Rapper Jay-Z, 76ers Sixers co-owner, Michael Rubin, and the owners of the Brooklyn Nets and this year’s Super Bowl team, The New England Patriots. They have just announced their launch of an organization that will lobby for changes to state probation and parole laws.
Mill has said, “[This is] one of the most important things that he has done in his life.” It is self-less that he has decided to use his platform to change the justice system.
The Rapper has been on probation for 11 arduous years and will not be taken off until 2023. “If you thought my case was unfair, there are millions of others dealing with worse situations and caught up in the system without committing crimes,” Meek Mill continues. “With this alliance, we want to change outdated laws, give people hope and reform a system that’s stacked against us,” he concluded.
Read the full article:
According to the U.S. Bureau of Justice Statistics over 4.6 million people are subject to probation or on parole in the United States and about one third of these parolees and probationers are black.
Clarise McCants, criminal justice campaign director for Color of Change, (Philadelphia) has said, “A lot of people saw what was happening to Meek Mill, and they saw not just one egregious situation, but a mirror of the thousands of egregious cases just like this.”
For example, on April 12, 2018 two black men were arrested by Philadelphia Police for allegedly trespassing at a Starbucks. The two said they were there for a business meeting, and were hauled away in handcuffs. A viral video of the incident was widely condemned as discriminatory. This also sparked protests and later apologies were given from Philadelphia’s police commissioner and the CEO of Starbucks.
Here is more about that incident:
“Yet again, we see how it’s so easy for black folks to get caught up in the system and get caught up in the trap,” Clarise McCants said.
Since his prison, Meek Mill has released a project called “Stay Woke” featuring singer-songwriter Miguel, where he raps about the unfair American justice system. He also has rapped about the system in his album titled, “Championships;” in songs like “What’s Free,” featuring Jay-Z and Rapper Rick Ross and other tracks on the album.
Meek Mill has taken his nightmare of prison and is turning it into many men’s dreams of getting out in his reform project.


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Digital Maps and Geospatial Data | Princeton University
Winter Weather United States 2001- 2009
|Click on map to preview values (download file to work with all data)
- Geological Survey (U.S.)
This polygon dataset shows winter weather events in the United States from 2001 to 2009. It is a subset of the Spatial Hazard Events and Losses Database for the United States (SHELDUS Version 7.0) that was compiled by the University of South Carolina. It portrays county-level hazard data for the United States, for the years 2001 to 2009. Included is information for 17 different natural hazard event types, as well as the total cost of damage due to natural hazards. The event type for this dataset is Winter Weather. For this event type, information is reported on property losses, crop losses, injuries, and fatalities in each county. The hazards information was derived from several existing national data sources such as the National Climatic Data Center's (NCDC) monthly Storm Data publications and the National Geophysical Data Center's Tsunami Event Database.
- United States, Alabama, Florida, Hawaii, Mississippi, Alaska, Arizona, Arkansas, California, Colorado, Connecticut, Delaware, District of Columbia, Georgia, Idaho, Illinois, Indiana, Iowa, Kansas, Kentucky, Missouri, Minnesota, Louisiana, Maine, Massachusetts, Michigan, Maryland, Montana, Nebraska, Nevada, New Hampshire, New Jersey, New Mexico, New York, North Carolina, North Dakota, Ohio, Oklahoma, Oregon, Pennsylvania, Rhode Island, South Dakota, South Carolina, Tennessee, Texas, Utah, Vermont, Virginia, Washington, West Virginia, Wisconsin, Wyoming, Northern Hemisphere, Western Hemisphere, and North America
- polygon, climatologyMeteorologyAtmosphere, environment, geoscientificinformation, Natural hazards and disasters, Natural hazards, Storms, Plants--Effect of ice on, Plants--Effect of freezes on, Plants--Effect of cold on, Freezes (Meteorology), Freezing precipitation, Blizzards, Snow., Sleet, and Freezing rain
- Held by:


Parliament has on Wednesday, December 15,2021 approved the 2022 budget estimates for two ministries.
The Transport and Railways Development Ministries have had their budget estimates approved by the House. The House unanimously approved a total sum of GHC921,843,000, 00 for the services of the ministry of transport and its other agencies for the year ending 31 December, 2022.
Moving the motion to the plenary, the Deputy minister for Transport, and MP for Upper west Akim, Fredrick Obeng Adom explained that, the ministry would be paying compensations GHC70, 298,000, goods and services GHC 157,184,000.00 Assets GHC 694,361,000.00.
GHC575,970,000.00 was also approved for the ministry for services of the ministry of Railways Development and its agencies for the year ending 31 December, 2022.
Moving the motion on the floor, the Railway Development sector minister, Mr John Peter Amewu took his time to break down the budget estimate as follows, Compensations GHC 5,291,000.00, goods and services, Ghc13,037,000.00, capital expenditure, Ghc 557, 642,000.00.
Mr Amewu explained to the House how important the Railways sector is to the President and would do everything possible to achieve the purpose for which the amount has been assigned.


presents Versus Synthesizer EnsembleUSA (Detroit)
Living techno god Carl Craig will join us for the 5th time. To celebrate this, he will perform a unique show "Versus", with no less than 5 live musicians. One of them is Fransesco Tristiano, who requires a grand piano on stage. A thrilling live show, for purists as well as ravers.


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Civil War Smack Talk
Okay, we all know that there a few teams in sports that fans love to hate. The New York Yankees, the Los Angeles Lakers, the Oakland Raiders and the Philadelphia Flyers.
Since the millennium, Oregon football has been on the rise. The Eugene Machine has steamrolled opponents, winning conference titles in 2000, 2001, 2009 and 2010 while earning multiple BCS bowl berths, including a trip to the 2010 Rose Bowl and the 2011 BCS National Championship Game.
They have also had their fair share of Heisman Trophy finalists, a Doak Walker award winner, and have broken and set lots of NCAA records along the way.
But its more than the team’s recent success, arrogance, and irritating constant uniform changes that has people hating them.
Especially, Oregon State Beaver fans.
Reason No. 5
The Oregon Duck mascot that does pushups after every time the team scores. One push up for each point. This is friggin’ annoying. We don’t need to see a close up and hear television commentators trying to figure out how many push-ups “the duck” has done so far in the game, or the season.
So you’re name is the Ducks, why not go out and rip off Disney’s Donald’s likeness right? No, because no one is intimidated by a duck for God’s sake.
The AFLAC duck has more personality, enough already!
Reason No. 4
Phil Knight and Nike.
He’s like the rich grandpa that spoils his grandchildren whenever they come to his house. But in the case, the Oregon Ducks actually live in the house that Phil built.
The ubber-rich co-founder of Nike has contributed large sums of money for upgrades to Autzen Stadium, built Matthew Knight Arena, a new football operations building, and many other buildings on campus.
Oregon fans love him like an adopted Donald Trump, but Oregon Sate fans really wish Knight would quit trying to buy the Ducks another Championship.
Stop it, our I will buy Adidas!
Reason No. 3
Stop changing uniforms its driving everyone crazy!
All we hear about is the more than 100 or so uniform combinations the Ducks have, thanks again, to Grandpa Phil Knight who by now must surely have a small textile factory staffed by 10-year Pakistani and Cambodian children making shoes, clothing and footballs on the Oregon campus.
In 2000, Oregon students protested that Nike should have random inspections of their factories, but still accepted Knight’s dirty money.
Have you no shame?
Reason No. 2
Player attitudes. Of course. Oregon fans call it “swagger”, but OSU fans can recognize a rude attitude when they see it. You can blame Chip Kelly for this one.
Looks like one annoying coach’s snarky remarks has rubbed off on the entire program. Take Cliff Harris for example. Even if all he did was refer to the BCS National Championship Game as “The Natty,” that’d be enough for most fans to instantly hate the Ducks.
But referring to Oregon State as Oregon’s “little brother.” War’s have been started for less.
Reason No. 1
Finally the No. 1 Reason Beaver fans hate the Oregon Ducks is, well, their annoying fans.
They just won’t shut up, while displaying small vaginas with their hands–everywhere.
They waft duck bill-shaped noise makers at the games that make a duck quacking sound when you blow through them. So the stands are always filled with tens of thousands of quack addicts.
From the student section to the alums, there is no rhyme or reason for their behavior. It’s not like they’ve won a Rose Bowl or anything? Just bad breeding, I guess.

domain: sports


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9 October 2007
Royal Festival Hall, Southbank Centre, London, UK
Gamelan Naga Mas was invited by the South Bank Centre in London to perform for the official reopening of the Royal Festival Hall by the Queen. The Queen accompanied her father when he opened the building in 1951. The Queen walked through the newly refurbished Spirit Level and listened to us perform Caping Gunung. Gamelan Naga Mas was joined by Sophie Clark and John Pawson from the Southbank Gamelan Players, and Matthew Cohen, an ex-Naga Mas member. Watch video from BBC London.
23 June 2007
Botanical Gardens, Glasgow, Scotland, UK
This was part of the East West Project bringing the Indonesian Gamelan to the West End of the Glasgow city. This event featured a family concert, Balinese story told by Margaret Smith with live Gamelan accompaniment, and a hands-on children workshop. The second concert featured new compositions influenced by Balinese, Javanese and Western music traditions.
Gamelan Naga Mas were invited to perform at the South Bank Centre Overture celebration which welcomed back the Royal Festival Hall after two years of restoration and redevelopment. Our programme combined traditional and new music inspired by Javanese, Balinese and Jazz musical traditions.
Gamelan Naga Mas took up residence at the Scottish Storytelling Centre for a golden day of Indonesian music with a Glasgow twist. A free family performance in the Centre’s Storytelling Court at 2pm provided a tantalising taster, while a hands-on family workshop at 3pm was a great way for everyone to explore the sights and sounds of the gamelan and have a go. An enchanting evening of spine-tingling music, dance and tales from Bali, Java and Scotland followed at 7pm performed by the Gamelan Naga Mas, and National Museums of Scotland's storyteller in residence, Marion Kenny.
10 February 2007
Children's Classic Concert - Ceilidhs to Carnival
Royal Concert Hall, Glasgow, Scotland, UK
Gamelan Naga Mas performed with puppeteer Malcolm Knight to an audience of 2000 in an all-action gala display of musical traditions from all around the world. Other bands on the day were the Harmony Chinese Music Ensemble, Treacherous Orchestra, Dhol Infusion, Rapido Mariachi, Carnival Samba and Dance Factory.