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[Show abstract][Hide abstract] ABSTRACT: The occurrence of Porphyromonas gulae, Porphyromonas macacae, Fusobacterium nucleatum and Fusobacterium canifelinum in subgingival plaque from dogs with and without periodontitis as well as their antimicrobial susceptibility were evaluated. From 50 dogs with periodontitis were identified 38 P. gulae, 8 P. macacae, 26 F. nucleatum and 15 F. canifelinum, and from 50 dogs without periodontitis were identified 15 P. gulae, 12 F. nucleatum and 11 F. canifelinum. All strains were susceptible to most of the antibiotics tested, however, different resistance rates to clarithromycin, erythromycin and metronidazole among strains were observed. The role of P. gulae, P. macacae, F. nucleatum and F. canifelinum in periodontal disease of household pets needs to be defined to a better prevention and treatment of the canine periodontitis.
[Show abstract][Hide abstract] ABSTRACT: A rapid PCR approach was developed to detect Porphyromonas gulae strains from subgingival samples of dogs with and with periodontitis. The presence of P. gulae was observed in 92% and 56%, respectively, in dogs with and without periodontitis. The new primer pair was specific to detect this microorganism, and this technique could be used to evaluate a correlation between periodontitis and P. gulae in companion animals.
[Show abstract][Hide abstract] ABSTRACT: Our goal was to establish a quantitative real-time PCR (QRT-PCR) method to detect Bacteroides fragilis group and related organisms from clinical specimens. Compared to conventional anaerobic culture, QRT-PCR can provide accurate and more rapid detection and identification of B. fragilis group and similar species. B. fragilis group and related organisms are the most frequently isolated anaerobic pathogens from clinical samples. However, culture and phenotypic identification is quite time-consuming. We designed specific primers and probes based on the 16S rRNA gene sequences of Bacteroides caccae, Bacteroides eggerthii, B. fragilis, Bacteroides ovatus, Bacteroides stercoris, Bacteroides thetaiotaomicron, Bacteroides uniformis, Bacteroides vulgatus, Odoribacter splanchnicus (Bacteroides splanchnicus), Parabacteroides distasonis (Bacteroides distasonis) and Parabacteroides merdae (Bacteroides merdae), and detected these species by means of QRT-PCR in 400 human surgical wound infection samples or closed abscesses. The target bacteria were detected from 31 samples (8%) by culture, but from 132 samples (33%) by QRT-PCR (p-value < 0.001). B. uniformis was the most common species (44 positive samples) according to QRT-PCR while culture showed it to be B. fragilis (16 positive samples). Additionally, for each species QRT-PCR detected higher counts than culture did; this may reflect detecting DNA of dead organisms by QRT-PCR. QRT-PCR is a rapid and sensitive method which has great potential for detection of B. fragilis group and related organisms in wound samples.
[Show abstract][Hide abstract] ABSTRACT: There is evidence of genetic predisposition to autism, but the percent of autistic subjects with this background is unknown. It is clear that other factors, such as environmental influences, may play a role in this disease. In the present study, we have examined the fecal microbial flora of 33 subjects with various severities of autism with gastrointestinal symptoms, 7 siblings not showing autistic symptoms (sibling controls) and eight non-sibling control subjects, using the bacterial tag encoded FLX amplicon pyrosequencing (bTEFAP) procedure. The results provide us with information on the microflora of stools of young children and a compelling picture of unique fecal microflora of children with autism with gastrointestinal symptomatology. Differences based upon maximum observed and maximum predicted operational taxonomic units were statistically significant when comparing autistic and control subjects with p-values ranging from <0.001 to 0.009 using both parametric and non-parametric estimators. At the phylum level, Bacteroidetes and Firmicutes showed the most difference between groups of varying severities of autism. Bacteroidetes was found at high levels in the severely autistic group, while Firmicutes were more predominant in the control group. Smaller, but significant, differences also occurred in the Actinobacterium and Proteobacterium phyla. Desulfovibrio species and Bacteroides vulgatus are present in significantly higher numbers in stools of severely autistic children than in controls. If the unique microbial flora is found to be a causative or consequent factor in this type of autism, it may have implications with regard to a specific diagnostic test, its epidemiology, and for treatment and prevention.
[Show abstract][Hide abstract] ABSTRACT: Eleven clinical strains isolated from infected wound specimens were subjected to polyphasic taxonomic analysis. Sequence analysis
of the 16S rRNA gene showed that all 11 strains were phylogenetically related to Slackia exigua. Additionally, conventional and biochemical tests of 6 of the 11 strains were performed as supplementary methods to obtain
phenotypic identification by comparison with the phenotypes of the relevant type strains. S. exigua has been considered an oral bacterial species in the family Coriobacteriaceae. This organism is fastidious and grows poorly, so it may easily be overlooked. The 16S rRNA gene sequences and the biochemical
characteristics of four of the S. exigua strains isolated for this study from various infections indicative of an intestinal source were almost identical to those
of the validated S. exigua type strain from an oral source and two of the S. exigua strains from oral sources evaluated in this study. Thus, we show for the first time that S. exigua species can be isolated from extraoral infections as well as from oral infections. The profiles of susceptibility to selected
antimicrobials of this species were also investigated for the first time.
[Show abstract][Hide abstract] ABSTRACT: Two strains of previously unknown Gram-stain-positive, anaerobic, coccus-shaped bacteria from human wound specimens were characterized using phenotypic and molecular taxonomic methods. Comparative 16S rRNA gene sequencing studies and distinguishable biochemical characteristics demonstrated that these two unknown strains, WAL 1855C(T) and WAL 2038E, are genotypically homogeneous and constitute a novel lineage within Clostridium cluster XIII. There was 13-14 % 16S rRNA gene sequence divergence between the novel strains and the most closely related species, Parvimonas micra, Finegoldia magna and species of Helcococcus. Based on the phenotypic and phylogenetic findings, a novel genus and species, Murdochiella asaccharolytica gen. nov., sp. nov., are proposed. Strain WAL 1855C(T) (=ATCC BAA-1631(T) =CCUG 55976(T)) is the type strain of Murdochiella asaccharolytica.
Full-text · Article · Sep 2009 · International Journal of Systematic and Evolutionary Microbiology
[Show abstract][Hide abstract] ABSTRACT: Three strains of an unidentified Gram-stain-variable, fastidious, catalase-negative, capnophilic, non-spore-forming, coccus-shaped bacterium from human wound specimens were characterized by phenotypic and molecular taxonomic methods. Initially, these strains were anaerobic; with repeated culture, they became aerotolerant. Comparative 16S rRNA gene sequencing studies demonstrated that the unknown strains were genealogically homogeneous and constituted a novel subline within the genus Gemella. The unknown bacterium was readily distinguished from other Gemella species by biochemical tests. On the basis of both phylogenetic and phenotypic evidence, it is proposed that the unknown bacterium from clinical specimens be classified as Gemella asaccharolytica sp. nov. The type strain is WAL 1945J(T) (=ATCC BAA-1630(T) =CCUG 57045(T)).
Full-text · Article · Sep 2009 · International Journal of Systematic and Evolutionary Microbiology
[Show abstract][Hide abstract] ABSTRACT: A coryneform strain, 06-1773O(T) (=WAL 19168(T)), derived from a groin abscess sample was characterized using phenotypic and molecular taxonomic methods. Comparative analyses revealed more than 3 % divergence of the 16S rRNA gene sequence and about 10 % divergence of the partial rpoB gene sequence from the type strain of Corynebacterium glucuronolyticum. The strain could also be differentiated from C. glucuronolyticum by a set of phenotypic properties. A DNA-DNA relatedness study between strain WAL 19168(T) and C. glucuronolyticum CCUG 35055(T) showed a relatedness value of 13.3 % (13.7 % on repeat analysis). The genotypic and phenotypic data show that the strain merits classification within a novel species of Corynebacterium. We propose the name Corynebacterium pyruviciproducens sp. nov. for the novel species. The type strain is 06-1773O(T) (=WAL 19168(T) =CCUG 57046(T) =ATCC BAA-1742(T)).
Preview · Article · Sep 2009 · International Journal of Systematic and Evolutionary Microbiology
[Show abstract][Hide abstract] ABSTRACT: Phenotypic and phylogenetic studies were performed on 15 isolates of an unidentified Gram-positive, anaerobic, non-sporulating coccobacillus-shaped bacterium isolated from human faeces. The novel organisms were catalase-negative, indole-negative and produced acetate and succinate as end products of metabolism. Comparative 16S rRNA gene sequencing demonstrated that the 15 isolates were highly related to each other and formed a hitherto unknown subline within the clostridial rRNA cluster XIVa. The novel isolates formed a robust phylogenetic group with a number of organisms which included Clostridium coccoides, Ruminococcus luti, Ruminococcus obeum and a number of other misclassified ruminococci. On the basis of these studies, a novel genus, Blautia gen. nov., is proposed. It is suggested that Clostridium coccoides, Ruminococcus hansenii, Ruminococcus hydrogenotrophicus, Ruminococcus luti, Ruminococcus productus, and Ruminococcus schinkii are transferred to this genus as Blautia coccoides gen. nov., comb. nov., Blautia hansenii comb. nov., Blautia hydrogenotrophica comb. nov., Blautia luti comb. nov., Blautia producta comb. nov. and Blautia schinkii comb. nov. One of the new isolates, the hitherto unknown coccus-shaped bacterial strain WAL 14507T (=ATCC BAA-1564T=DSM 19850T) is proposed as representing the type strain of a novel species, Blautia wexlerae sp. nov.
Preview · Article · Sep 2008 · International Journal of Systematic and Evolutionary Microbiology
[Show abstract][Hide abstract] ABSTRACT: Two proposed hypotheses for irritable bowel syndrome (IBS) are acute gastroenteritis and bacterial overgrowth. We studied whether acute infection with Campylobacter could precipitate bacterial overgrowth in a rat model in order to link the two hypotheses.
Sprague-Dawley outbred rats were randomly administered a vehicle or Campylobacter jejuni strain 81-176 by oral gavage. Three months after clearance of the infectious agent, rats had a stool consistency evaluation. After euthanasia, lumenal bacteria counts were measured via quantitative real-time PCR from self-contained segments of the duodenum, jejunum, ileum, cecum and left colon. Adjacent sections of bowel were fixed in formalin for evaluation of intraepithelial lymphocyte counts.
Three months after clearance of Campylobacter infection, 57% of Campylobacter infected rats had some alteration in stool consistency compared to 7.4% in mock-infected controls (P < 0.001). Among the rats that received Campylobacter, 27% had evidence of bacterial overgrowth by PCR. These rats also had the highest prevalence of altered stool form and had lower body weight. Consistent with post-infectious IBS in humans, bacterial overgrowth rats demonstrated a significant increase in rectal and left colon intraepithelial lymphocytes.
Acute infection with C. jejuni 81-176 precipitates alterations in stool consistency, bacterial overgrowth and rectal lymphocytosis consistent with findings in IBS patients.
No preview · Article · Apr 2008 · Digestive Diseases and Sciences
[Show abstract][Hide abstract] ABSTRACT: Three groups of previously unknown gram-positive, anaerobic, coccus-shaped bacteria were characterized using phenotypic and
molecular taxonomic methods. Phenotypic and genotypic data demonstrate that these organisms are distinct, and each group represents
a previously unknown subline within Clostridium cluster XIII. Two groups are most closely related to Peptoniphilus harei in the genus Peptoniphilus, and the other group is most closely related to Anaerococcus lactolyticus in the genus Anaerococcus. Based on the findings, three novel species, Peptoniphilus gorbachii sp. nov., Peptoniphilus olsenii sp. nov., and Anaerococcus murdochii sp. nov., are proposed. The type strains of Peptoniphilus gorbachii sp. nov., Peptoniphilus olsenii sp. nov., and Anaerococcus murdochii sp. nov. are WAL 10418T (= CCUG 53341T = ATCC BAA-1383T), WAL 12922T (= CCUG 53342T = ATCC BAA-1384T), and WAL 17230T (= CCUG 53340T = ATCC BAA-1385T), respectively.
[Show abstract][Hide abstract] ABSTRACT: A rapid multiplex PCR approach was developed to detect the bft gene subtypes in Bacteroides fragilis clinical isolates. This technique could be used to look at the epidemiology of enterotoxigenic strains of B. fragilis in clinical infections and whether there is a correlation between disease and the presence of B. fragilis enterotoxin.
Full-text · Article · May 2007 · Journal of Clinical Microbiology
[Show abstract][Hide abstract] ABSTRACT: Gram-positive anaerobic cocci (GPAC) are a heterogeneous group of organisms that are isolated from clinical specimens more often than any group of anaerobic bacteria except Bacteroides species, yet many strains are still difficult or impossible to identify in the diagnostic laboratory. In this study, a total of 124 strains, including 13 reference strains of GPAC species and 111 isolates that had been recovered from clinical specimens previously and identified by 16S rRNA gene sequencing, were subjected to biochemical characterization. Based on the results, a short biochemical scheme that involves the minimum essential biochemical tests for accurate identification of clinically important GPAC was developed.
Preview · Article · Mar 2007 · Journal of Clinical Microbiology
[Show abstract][Hide abstract] ABSTRACT: Two groups of previously unknown Gram-negative, strictly anaerobic, pigment-producing, rod-shaped bacteria, which phenotypically and phylogenetically displayed a close association with the recently described species Alistipes finegoldii, were characterized using phenotypic and molecular taxonomic methods. A 16S rRNA gene sequence divergence of approximately 3 % between the two unknown bacteria and A. finegoldii, as well as distinguishable biochemical characteristics, demonstrates that these organisms are genotypically and phenotypically distinct and that each group represents a previously unknown subline within the genus Alistipes. Chromosomal DNA-DNA reassociation studies further confirmed the separateness of the unidentified bacteria and A. finegoldii. On the basis of the phenotypic and phylogenetic findings, two novel species, Alistipes onderdonkii sp. nov. and Alistipes shahii sp. nov., are proposed. The type strains of A. onderdonkii and A. shahii are WAL 8169(T) (=CCUG 48946(T)=ATCC BAA-1178(T)) and WAL 8301(T) (=CCUG 48947(T)=ATCC BAA-1179(T)), respectively; their DNA G+C contents are 58 and 56 mol%, respectively.
Full-text · Article · Sep 2006 · International Journal of Systematic and Evolutionary Microbiology
[Show abstract][Hide abstract] ABSTRACT: Phenotypic and phylogenetic studies were performed on an unknown gram-negative, strictly anaerobic, rod-shaped bacterium isolated
from human clinical specimens. This organism was indole negative, resistant to 20% bile, produced acetic and a lesser amount
of succinic acids as the major end products of glucose metabolism, and possessed a G+C content of approximately 43 mol%. Comparative
16S rRNA gene sequencing demonstrated that the unidentified bacterium was a member of the Cytophaga-Flavobacter-Bacteroides phylum of gram-negative bacteria and formed a close association (with an average sequence similarity of 93.6%) with the second
subcluster of the Porphyromonas cluster in the Bacteroides subgroup. Phylogenetically and phenotypically it resembled Bacteroides merdae; however, a 16S rRNA gene sequence divergence of approximately 5.5% between the unknown bacterium and B. merdae, as well as distinguishable biochemical characteristics, demonstrate that the unknown bacterium is genotypically and phenotypically
distinct and represents a previously unknown subline within the Porphyromonas phylogenetic cluster. Furthermore, a DNA-DNA reassociation value of 17.8% between isolates WAL 12034T (the type strain of this novel taxon) and ATCC 43184T (B. merdae type strain) also documented the separateness of the unknown species and B. merdae. Based on the phenotypic and phylogenetic findings, a new species, “Bacteroides goldsteinii sp. nov,” is proposed. The G+C content of the DNA is 43 mol% for Bacteroides. The type strain of “B. goldsteinii” is WAL 12034T (= CCUG 48944T = ATCC BAA-1180T).
Preview · Article · Oct 2005 · Journal of Clinical Microbiology
[Show abstract][Hide abstract] ABSTRACT: Porphyromonas levii is an anaerobic, pigmented gram-negative bacillus originally isolated from bovine rumen. We describe 58 human clinical strains
of P. levii-like organisms, isolated from various human clinical specimens that are phenotypically similar to the type strain of P. levii, a rumen isolate (ATCC 29147). Our biochemical, comparative 16S rRNA sequence analyses, and DNΑ-DNA relatedness studies indicate
that the human P. levii-like organisms are similar to each other but genetically different from the P. levii type strain isolated from bovine rumen. We therefore propose the name Porphyromonas somerae to encompass the human P. levii-like organisms. P. somerae was predominantly isolated from patients with chronic skin and soft tissue or bone infections, especially in the lower extremities.
Preview · Article · Oct 2005 · Journal of Clinical Microbiology
[Show abstract][Hide abstract] ABSTRACT: Sequence analysis of the 16S rRNA gene represents a highly accurate and versatile method for bacterial classification and
identification, even when the species in question is notoriously difficult to identify by phenotypic means. In this study,
we evaluated the utility of 16S rRNA gene sequencing as a means of identifying clinically important Bacteroides species. We sequenced 231 clinical isolates that had been identified by a short biochemical scheme. Based on the sequence
analysis, 192 clinical isolates were assigned to an established species, with the other 39 clinical strains revealing five
unique sequences that may represent five novel species. This is in contrast to identification obtained from a short biochemical
scheme, by which only 73.5% (172 of 231) of isolates were correctly identified to species level. Based on the solid identification
obtained from 16S rRNA gene sequencing, the short biochemical scheme was modified and improved to provide clinical laboratories
with an inexpensive and simple alternative for the identification of isolates of clinically significant Bacteroides species.
Preview · Article · May 2005 · Journal of Clinical Microbiology
[Show abstract][Hide abstract] ABSTRACT: Clostridium hathewayi and Campylobacter hominis have not been previously reported in infection. We report a fatal case of septicemia, massive intravascular hemolysis, shock, and disseminated intravascular coagulation; both of these organisms were recovered on blood culture, although it seems likely that the C. hathewayi was responsible for the clinical picture and that the C. hominis was an incidental finding.
[Show abstract][Hide abstract] ABSTRACT: The activities of OPT-80 against 453 intestinal bacteria were compared with those of seven other drugs. OPT-80 showed good
activity against most clostridia, staphylococci, and enterococci, but streptococci, aerobic and facultative gram-negative
rods, anaerobic gram-negative rods, and Clostridium ramosum were resistant. Poor activity against anaerobic gram-negative rods may maintain colonization resistance.
Preview · Article · Jan 2005 · Antimicrobial Agents and Chemotherapy
[Show abstract][Hide abstract] ABSTRACT: Based on the hypothesis that intestinal clostridia play a role in late-onset autism, we have been characterizing clostridia
from stools of autistic and control children. We applied the TaqMan real-time PCR procedure to detect and quantitate three
Clostridium clusters and one Clostridium species, C. bolteae, in stool specimens. Group- and species-specific primers targeting the 16S rRNA genes were designed, and specificity of the
primers was confirmed with DNA from related bacterial strains. In this procedure, a linear relationship exists between the
threshold cycle (CT) fluorescence value and the number of bacterial cells (CFU). The assay showed high sensitivity: as few as 2 cells of members
of cluster I, 6 cells of cluster XI, 4 cells of cluster XIVab, and 0.6 cell of C. bolteae could be detected per PCR. Analysis of the real-time PCR data indicated that the cell count differences between autistic
and control children for C. bolteae and the following Clostridium groups were statistically significant: mean counts of C. bolteae and clusters I and XI in autistic children were 46-fold (P = 0.01), 9.0-fold (P = 0.014), and 3.5-fold (P = 0.004) greater than those in control children, respectively, but not for cluster XIVab (2.6 × 108 CFU/g in autistic children and 4.8 × 108 CFU/g in controls; respectively). More subjects need to be studied. The assay is a rapid and reliable method, and it should
have great potential for quantitation of other bacteria in the intestinal tract.
Preview · Article · Dec 2004 · Applied and Environmental Microbiology


'Copy text in Rich Text format' option affects block select copy & paste in v12.8
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In 12.7 it works the correct way if the option is ticked or unticked.
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A Fast Diagnostic Symptom Checker App
Symptomia is a medical diagnostic tool that is based on the needs of medical students and professionals. It is an app that allows quick access to medical information based on the most common symptoms - useful both at the hospital bedside and in the ambulatory.
- Fast Symptomatic Interface
- Expanded, Modern Medical Information
- Especially Made for Medical Students and Young Doctors
- Written to Augment Doctor-Patient Communication
- Fast Search
- Bookmarking Feature
A Useful Aid for Diagnosis Symptomia was developed to aid in the medical diagnosis process by offering a fast, easy-to-use, and always-available source of selected medical information.
Emphasis on Patients Symptomia is a diagnostic aid that is based on the needs of medical students during their clerkship years and young doctors during their specialty training. They need quick access to medical information built-up around patients' complaints at the hospital bedside and the ambulatory.
Emphasis on Symptoms Symptomia places emphasis on symptoms because people seek medical advice based on observed symptoms. For the doctor, the diagnostic process also begins with observables. As a patient's illness is always to some extent uncertain, a diagnostic hypothesis must frequently consider multiple diseases or syndromes.
Facilitating Diagnosis In recent years, flowcharts and algorithms have been widely introduced as aids in problem solving. They typically consist of a single entry point, such as a symptom or a lab result. Diagnostic logic then suggests a possible clinical diagnosis. The flowchart method falters however, when a patient manifests multiple problems or diseases.
The diagnostic process is an iterative one that involves gathering data and making decisions about their diagnostic significance. This problem-solving process can be facilitated by additional medical information, especially if the information is readily available. This is where Symptomia helps.
For example, if a patient has a sudden, extremely severe headache, the symptoms might indicate the possibility of a brain haemorrhage, migraine, cluster headache, or meningitis. Additional information supplied by Symptomia can help in establishing a diagnostic possibility.
Professional Problem-Solving Symptomia has been developed as a tool to supply pertinent information about a variety of possible disorders that a given symptom can suggest. The diagnosis is left in the hands of professionals. With fast access to an expanded up-to-date medical reference, the app has a fast user interface to aid in the process of differential diagnosis. With only two taps on the screen, the most commonly observed medical symptoms and their relevant information can be reached.
Symptomia has a bookmarking feature so that saved entries are even quicker to reach the next time. There is also a fast search function to quickly find a medical topic by name.
Symptomia is written in a language that augments doctor-patient communication.Medical text is written and edited by Dr. Andrzej Wojtczak, MD, PhD, MDSc. He is a professor of medicine and public health, former chariman of a clinical department of medicine, editor of medical textbooks of internal medicine, devoted academic teacher and a long-term expert and senior staff member of the World Health Organization.

domain: health


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On Thursday, November 14th, through Saturday, November 16th, the biannual Friends of the Libraries used book sale will take place at Alden Library’s fourth floor 1951 Lounge.
On Thursday evening from 7 p.m. to 9 p.m., eager shoppers can attend the special “preview sale,” which offers a first choice of books at doubled prices.
On Friday from 10 a.m. to 6 p.m. and Saturday from 10 p.m. to 4 p.m., most books cost just a dollar. Some paperbacks sell for $.25, while more valuable items vary in price.
The selection is extensive. Art Woolley, English professor emeritus and volunteer chair of the Friends of the Libraries book sale, has spent weeks up in “the cage” of the seventh floor of Alden Library organizing piles of glossy books into easy-to-browse classifications. Sleek coffee table books, novels, antiqued volumes with gilded spines, cookbooks, DIY guides, and atlases bursting with colored photographs line the shelves.
All of these are sorted into categories such as fiction and poetry, political science, foreign language, children & youth, humanities, business, education, natural sciences and fine art.
Approximately 1,500 items were donated over the summer, including DVDs, books-on-audio-cassettes, VHS tapes and vintage videodiscs from the ‘80s. Many of the materials come from the personal and professional collections of retiring OHIO faculty, Woolley said.
Woolley is quick to credit donors and others who make the sale possible. Two OHIO School of Business organizations, CONNECT and Delta Sigma Pi, run the donations from the stacks to the fourth floor, and fourteen or so volunteers monitor the event.
Each sale, he said, attracts an average of 210 shoppers, yielding a total of three to four thousand dollars for the Libraries each year. The proceeds have funded a variety of causes, including student employee scholarships, the Friends of the Library study room, and skeleton models for the second floor learning commons.
But those contributions are just happy consequences of the main event: the celebration of books. Looking over the shelves of eclectic donations, Woolley’s admiration of the medium is palpable.
“There’s an incredible variety of value,” he concluded. It’s a keen observation —monetarily speaking and otherwise.
Join us for the Friends of the Libraries book sale on Thursday, November 14th, from 7 p.m. to 9 p.m.; Friday, November 15th from 10 a.m. to 6 p.m.; and Saturday, November 16th from 10 p.m. to 4 p.m. on the fourth floor of Alden Library.

domain: news


After the release of Apple’s new 13-inch MacBook Pro with the M2 chip, the $1,299 base model with 256GB of storage was found to have significantly slower SSD read/write speeds than the equivalent generation model.
youtube channel like max technology You technology made Tested the 256GB model with Blackmagic’s Disk Speed Test app and found the SSD’s read and write speeds to be around 1450MB/s, which is about 50% slower reads and 30% slower. % Slower write speeds than the 13-inch MacBook Pro with the M1 chip and 256GB of storage.
Disk Speed Test app numbers shared by Max Tech’s Vadim Yuryev:
- MacBook Pro 13-inch (M1/256GB) Read Speed: 2900
- 13-inch MacBook Pro (M2/256GB) Read Speed: 1446
- 13-inch MacBook Pro (M1/256GB) Write Speed: 2215
- 13-inch MacBook Pro (M2/256GB) Write Speed: 1463
Yuryev took apart the new 13-inch MacBook Pro and found that the 256GB model is equipped with a single NAND flash storage chip, while the older model has two NAND chips that are likely to be 128GB each. This difference probably explains why the newer models have slower SSDs, as multiple NAND chips allow faster speeds in parallel.
It appears that only the base model 13-inch MacBook Pro with the M2 chip has a slower SSD. as written In MacRumors forums, Aaron Zolo Ran the Disk Speed Test app on the 512GB model and SSD read/write speeds were similar to all M1 models, but getting these speeds would require spending at least $1,499. This probably means that the 512GB model is still equipped with two 256GB flash storage chips.
It’s unclear why the new entry-level 13-inch MacBook Pro is equipped with only one NAND chip, but cost and/or lack of supply are two likely factors. We’ve reached out to Apple for comment and will update this story if we hear back.
Slow SSD speeds can affect normal tasks such as transferring files to an external drive, and overall performance can also take a slight hit as Macs temporarily use SSD space as virtual memory when physical RAM is fully available. is used to. If you’re considering the new 13-inch MacBook Pro and faster SSD speeds are important to you, we recommend ordering a model with at least 512GB of storage (or better yet, the new MacBook Air in July). wait for).
The new 13-inch MacBook Pro was launched on Friday. The base model’s slow SSD speed was not mentioned in many (any?) restricted reviews of the laptop, as it appears that Apple provided several reviewers with a 1TB configuration for testing.
Whether the new MacBook Air with the M2 chip will even have slower SSD speeds when configured with 256GB of storage remains to be seen.


Wednesday, Washington State Attorney General Bob Ferguson announced a complaint has been filed in U.S. District Court of Eastern Washington, claiming sexual harassment of farm workers by a foreman working for a large ag company in Quincy, WA
You may have heard of the "What's Upstream" campaign that was launched by money from the Environmental Protection Agency Region 10 (The Pacific Northwest) that many say was a cleverly disguised attack on farmers, ranchers and other ag producers by environmental groups. Now, there's evidence taxpayer money was used to fund the effort, in violation of federal laws.
Last night the National Weather service issued severe weather warning’s all around the Tri-Cities and lucky for us the bad weather missed us all together. Check out my photo’s from Terra Blanca winery last night.


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Even though What Brazil is doing is almost as bad as what we did to our indigenous populations to satisfy our Manifest Destiny, and the man made fires are a problem for climate change, taking the law into our own hands only creates instability and causes more problems for the Brazilian People!! We must stop being the bully of the world and cooperate with other countries thru The UN to pressure other countries into compliance with norms that help humanity survive the ignorance, hatred and stupidity of humankind!!
Let’s turn to ourselves as one of the biggest polluters of all time and vote for The New Green Deal for ourselves! Let’s put our defense spending to improving education, our public health and eliminating poverty!!

domain: sociology


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Keanu felt a bit of an outcastKeanu Reeves has confessed he felt just like his outcast character in 47 Ronin, as the only non-Japanese member of the cast.
The Hollywood heartthrob plays outcast Kai in the 3D adaptation of a classic Japanese tale about 47 samurai in 18th-century Japan who avenge the murder of their master.
Keanu revealed: "Even though everyone was really nice to me and we got along great and it developed great, I still couldn't hang out and speak Japanese, so in a way I was always Kai. I could say 'Good morning,' and 'Nice to meet you,' and all that but I couldn't hang out."
The 49-year-old Canadian actor has made a string of martial arts movies and admitted: "I've always been drawn to eastern culture."
The Matrix star had to learn how to use a Katana, the traditional Japanese long sword.
He said: "I'd never worked with a Katana before, that was fun. Even though it's a fake fight and it's movie fighting, you still have to have technique. I'm a beginner, but I got to be very specific, so that helped. I got to do some horseback riding, so that was a blast, I loved that.
"It was just training, eat right, go to work."

domain: entertainment


Ford Expedition Questions Maintenance & Repair
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When ignition is turned off, a motor/I think continues to run under the hood on the right side as viewed from the front. It is located below the huge air filter chamber and appears to have brake line...
What could cause this? And will it be costly?
Location of the low A/C recharge port for 2001 ford Eddie Bauer 5.4 engine 4x4
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Code said it was misfiring on cylinder 6. Replaced coil, plug, and injector. Doing better but still a stutter on gradual acceleration. Seems to be worst when accelerating up even a slight incline...
I have looked everywhere to find out where it goes. Can anyone help? Thanks, Tony
The fuses are under the dash board inside the car. The fuse is bad and therefore it keeps draining my battery.
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GAITHERSBURG – Last week the Jones Lane Elementary School Parent Teacher Association sponsored “Ability Awareness Week,” a week-long series of presentations to the student body by speakers with different physical and mental handicaps. The presentations were intended to demonstrate to the students that people with disabilities can still live productive and fulfilling lives.
Luis Carlos Montalvan, a former U.S. Army Captain who served two deployments in Iraq and was awarded two Bronze Stars, a Purple Heart and the Army Commendation for Valor before his discharge in 2007, spoke on Wednesday. Montalvan walks with a cane and suffers from post-traumatic stress disorder (PTSD.)
“Coming home from the war was in many ways more challenging than the war itself,” Montalvan said. “Recovering from the effects of war is something that’s consumed much of my time, along with trying to help others with their own healing processes.”
Montalvan’s service dog Tuesday, a professionally trained golden retriever, accompanied him on Wednesday. For more than six years, Tuesday has provided Montalvan with practical and emotional support. The dog can fetch needed objects, provide balance for Montalvan when he descends a staircase and respond to shifts in his mood, including waking him from a nightmare. Montalvan published his first book, “Until Tuesday: A Wounded Warrior and the Golden Retreiver Who Saved Him”, in 2011.
Last year, Montalvan published another book, “Tuesday Tucks Me In”. Written for younger readers, the book describes a day in Montalvan’s life from Tuesday’s point of view. Montalvan and Tuesday, who live in Manhattan, have been interviewed on national television and have toured regularly over the last three years.
“The most rewarding part of the experience is hearing personal stories from people,” Montalvan said. “I love to hear them describe how much one of the books meant to them, how it may have improved the relationship they have with their child. A teacher will send us a note saying their kids love it, that it’s their favorite book.”
In his presentation, Montalvan spoke in front of the entire student body about his mutually beneficial relationship with Tuesday and read “Tuesday Tucks Me In.” He tossed aside his cane and Tuesday quickly retrieved it, bringing applause from the students. After the speech, students lined up to meet Montalvan, get copies of the book signed and pet Tuesday.
“He’s such an exuberant, happy soul,” Montalvan said of Tuesday. “It’s infectious. His happy spirit has really influenced my own and lessened many of the effects of PTSD. He’s helped motivate me to get better.”
“We are so honored that Captain Montalvan came to visit our school,” said Stacy Kravitz, a member of the Jones Lane PTA and the Ability Awareness committee. “Our students were able to see firsthand how a service dog can help someone with a disability live a more productive and independent life. We want our students to learn that those who live with disabilities are special and unique with valuable gifts to offer. We hope the activities of the week encourage the kids to advocate for and accept those who have learning or emotional differences and physical disabilities.”
Montalvan and Tuesday spoke at several other Maryland schools in the following days.


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More Fair Trade coffee in Scooter's
By Mike Klein, Justice and Peace Studies
Now you have another option for "advancing the common good" in your morning mug of coffee. In addition to choosing Dunn Brothers' Fair Trade brewed coffee, you now can purchase whole bean coffee in Scooter's. Flamenco Organic imports coffee from the Café Femenino Foundation, supporting women coffee farmers in developing countries. The foundation's Web site tells the story:
“Women farmers participate in all farm activities. They prepare the terrain, nurseries, and the compost. They fertilize the soil and prepare bio-fertilizers, as well as harvesting, de-pulping, fermenting, and drying the coffee. It is very rare for women to participate in selling the coffee or making decisions on how the money from coffee sales will be used. Insufficient funds and a full spectrum of social problems have hindered attempts to intervene. But with the payment of organic and the Fair Trade premiums, efforts are underway to promote the organization of the female coffee farmers and their integration into social, political, and occupational organizations. The Café Femenino Foundation supports efforts to improve the view of women’s roles by supporting programs and projects that generate sales the women can control. The women are excited by the potential, and have received support from community leaders.”
The principles of fair trade echo the themes of Catholic social thought:
- Fair price: Democratically organized farmer groups receive a guaranteed minimum floor price and an additional premium for certified organic products. Farmer organizations are also eligible for pre-harvest credit.
- Fair labor conditions: Workers on Fair Trade farms enjoy freedom of association, safe working conditions, and living wages. Forced child labor is strictly prohibited.
- Direct trade: With Fair Trade, importers purchase from Fair Trade producer groups as directly as possible, eliminating unnecessary middlemen and empowering farmers to develop the business capacity necessary to compete in the global marketplace.
- Democratic and transparent organizations: Fair Trade farmers and farm workers decide democratically how to invest Fair Trade revenues.
- Community development: Fair Trade farmers and farm workers invest Fair Trade premiums in social and business development projects such as scholarship programs, quality improvement trainings, and organic certification.
- Environmental sustainability: Harmful agrochemicals and GMOs are strictly prohibited in favor of environmentally sustainable farming methods that protect farmers’ health and preserve valuable ecosystems for future generations.
Advance the common good by choosing Fair Trade when you buy your next cup of coffee, and shop for fair trade gifts at the Fair Trade Sale from 10 a.m. to 4 p.m. next Monday and Tuesday, Dec. 4 and 5, in Campus Square, lower level, Murray-Herrick Campus Center.
Visit Scooter's for more information on Flamenco Organic Coffee and e-mail Mike Klein for information on the Fair Trade Sale.


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It’s not a misprint.
If you’re scrolling through your television listings on Christmas Day, you’ll see two N.F.L. games on the schedule, which could be a bit of a reprieve from the holiday meal and festivities (or from the slate of N.B.A. games).
One of the matchups, on paper, should be better than the other, but both games will feature high-profile stars, including Aaron Rodgers, the league’s reigning most valuable player, as well as Davante Adams, Kyler Murray, Myles Garrett and Jonathan Taylor.
Below is everything you need to know about the N.F.L.’s games on Saturday.
Cleveland Browns at Green Bay Packers
4:30 p.m., Fox and NFL Network
Facing a coronavirus outbreak, the N.F.L. rescheduled Cleveland’s game last week, and the Browns (7-7) narrowly lost to the Raiders on Tuesday thanks to a walk-off field goal. But Cleveland’s roster was depleted by coronavirus absences, including its top two quarterbacks, Baker Mayfield and Case Keenum, as well as Coach Kevin Stefanski. The Browns’ postseason chances stand at 21 percent, the result of an up-and-down season with injuries and inconsistent play from Mayfield. One of the few bright spots has been Garrett, who is tied for third in the league in sacks with 15. But even he is questionable to play with a groin injury.
As of Wednesday morning, neither Mayfield nor Keenum had cleared the health protocols, putting Nick Mullens, the team’s third-string quarterback, in line to start again. But regardless of who is starting at quarterback, the matchup against Green Bay will be tough. The Packers (11-3) arguably have the best home-field advantage in the league, and forecasts call for the temperature to be near freezing with winds at 10 miles an hour.
Aaron Rodgers, as usual, is playing efficiently, completing nearly 68 percent of his passes, and he has thrown for 3,487 yards and 30 touchdowns. Eight of those touchdowns were caught by Davante Adams, who ranks third in the league in receiving yards (1,248) and fourth in catches (96).
The Packers defense has also played well, allowing only two teams to rush for more than 150 yards and allowing an average of 217.9 passing yards per game. The Packers have already clinched the N.F.C. North and currently hold the conference’s No. 1 seed, meaning the road to the playoffs runs through Lambeau Field.
Green Bay is justifiably a 7.5-point betting favorite, and if the Browns, short-handed or not, falter in any area of the game, it could get ugly.
Indianapolis Colts at Arizona Cardinals
8:15 p.m., NFL Network
Once considered the N.F.L.’s best team as they burst to a 10-2 start, the Cardinals (10-4) have lost two consecutive games and are declining, a bad sign this close to the postseason. In both of its recent losses, Arizona’s offense looked inefficient as Kyler Murray threw inaccurate passes and misfires. The Cardinals have also played without their best weapon, DeAndre Hopkins, who was placed on injured reserve with a hamstring injury. The team hopes he can return for a playoff push. A loss to the Colts (8-6) would drop the Cardinals’ chances of winning the N.F.C. West to 43 percent, meaning their hard-earned work earlier in the season could be wasted and they would be in jeopardy of losing home-field advantage for a postseason game.
The arc of the season for Indianapolis has been the opposite. The Colts started 3-5, but have won five of their last six games. In that stretch, the team unleashed Jonathan Taylor, and the running back has become one of the N.F.L.’s best players. He leads the league in the major rushing categories, with 270 carries, 1,518 yards and 17 touchdowns. His emergence has taken pressure and responsibility off Carson Wentz, whom the team traded for this off-season with the goal of reviving his career under Coach Frank Reich after Wentz’s five up-and-down seasons with the Philadelphia Eagles. The Colts defense is also stout, especially the front seven, and allows only 109 rushing yards per game.
The Cardinals are the betting favorite (-2), and will need to play like it to reverse their downward slope.


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Tonight I have the series premiere of Legends of Tomorrow, another spin off from Arrow (Flash was the first). "Pilot":
In the future, Vandal manages to do what no one else in history has ever accomplished: take over the entire world. That's why Time Master Rip Hunter becomes motivated to go back to 2016 and assemble a ragtag group of heroes. He wants them to join him aboard his time machine ship called the Waverider and attempt to thwart Vandal across time, hopefully stopping him before the horrible future where Rip comes from happens.
It looks awesome!
Looks like I've got a lot of nonfiction on my Kindle. I'm going to have to add something to my current reads.
PK the Bookeemonster


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American Santa Christmas Ornament
Personalized Christmas Ornament
Dimensions: 3" x 6 1/2"
Material: Polish Glass
Show your patriotic side with this Uncle Sam Santa Claus ornament from Poland. He wears the traditional patriotic top hat with stars and stripes, lovingly holds the Statue of Liberty in his hands symbolizing freedom, the bald eagle or Great Seal of the United States in the other and a basket of plenty showing the many opportunities that are available in America, creating an ethnically diverse country. Made of Polish glass, with fine details and glittery accents this personalized patriotic ornament will make a wonderful addition to your holiday decorating.
As a proud West Point parent, I bought this for my recent grad to have on his own tree. One can never have enough Santa's on the tree, but this one is beyond perfect.
Love this American Santa as the details are wonderful. Shows perfectly with my other red, white & blue "Old Glory" ornaments that I proudly display on my "Military/Proud of the USA" tree! Was so excited, that I ordered 2 more to give as gifts.
Read what our customers say about our Personalized Christmas Ornaments and their shopping experience!Hover over testimonials to stop scrolling
12/9/2016 - "I ordered ornaments from you last year and was very satisfied. I order ornaments every year for all my grandchildren and have done this since they were born. Barbara M."
3/21/2017 - "Good selection of beautiful ornaments for gifts to celebrate special occasions in an individuals life. A nice gift for children of all ages and for adults, too. The Ornament Shop carefully packages products for mail delivery. Margaret M."
12/16/2016 - "Thank you for a good experience. Charleen P."
11/21/2016 - "Love being able to send Personalized Christmas ornaments to the kids. They can look back at what they were into on a specific year. One year camping, soccer, baby's first xmas, wedding dates, travels to NYC, so awesome to have their history on the Christmas tree. Janette S."
11/19/2016 - "Very pleased with purchases. Easy to use website. Great variety of ornaments.Becky F."
10/4/2016 - "Excellent company!!! Christmas ornaments are of very good quality and very good prices. The variety of ornaments is outstanding! Susan W."
10/24/2016 - "Beautiful Ornaments. Very detailed James C."
11/27/2016 - "It was great! Enjoyed the site and the selection. Jamie C."
11/23/2016 - "Very quickly resolved incorrect engraving. Tanny T."
9/9/2016 - "We have a mixed race family, it would be good to have the origin of the races, like African American, Mexican, Asian, etc for each of the members of the family. Clifford L."

domain: artistic


text:
One True Loves audiobook
Hi, are you looking for One True Loves audiobook? If yes, you are in the right place! ✅ scroll down to Audio player section bellow, you will find the audio of this book. Right below are top 5 reviews and comments from audiences for this book. Hope you love it!!!.
One True Loves audiobook free
Simply stated, this was a poignantly written story about true love… I am not one to write a review that gives a play by play of the plot, but I want to convey that this is an utterly amazing novel that connects you to the heart and soul of the extremely well-developed characters. The pace of this deeply moving story was perfect…Taylor Jenkins Reid is an exceptionally gifted author with the ability to captivate, entertain and emotionally engage the reader through her powerful writing. And Julia Whelan\’s narration captured the emotions of the character beautifully! Happy Listening!!!
One True Loves audiobook streamming online
Beautifully written, beautifully read. I loved it. Would definitely recommend to anyone. Loved the ending.
Audiobook One True Loves by Taylor Jenkins Reid
Though I\’m not big on romantic novels I bought this one on a daily deal based in the reviews. I was not disappointed. I enjoyed the relationship challenges between all the characters. Worth the time and money.
Audio One True Loves narrated by Julia Whelan
I loved how the story and the characters developed. the narration was amazing as always my only criticism would he tht I wish tht there was more of an epilogue. But, an amazing book none the less
Free audio One True Loves – in the audio player below
This book made me cry and when don\’t usually cry. Worth a credit. You will love it.


text:
The ionic and ground states of gamma-pyrone. The photoionization spectrum studied by synchrotron radiation, and interpreted by configuration interaction and density functional calculations
MetadataShow full item record
A synchrotron-based photoionization spectrum up to 27 eV represents a considerable improvement in resolution over early He(I) and He(II) spectra. Symmetry-adapted coupled cluster calculations of the ionic state sequence give the sequence of state vertical ionization energies (VIE) as 12B2 < 12B1 < 12A2 < 22B1 < 12A1. Generally, these symmetry-adapted cluster configuration interactions VIE match reasonably well with the experimental spectrum over this wide energy range. Density functional calculations of the corresponding adiabatic terms (AIE) were also performed. Higher energy ionic states were determined by complete active space self-consistent field methods; these include all π-ionizations and some σ-ionic states. These were analyzed by Franck–Condon (FC) procedures and compared with an experiment. The spectral onset is complex, where two states, later shown to be the 12B2 and 12B1 states, are strongly overlapping. The superposition of the FC vibrational structure in the 12B2 and 12B1 states accounts for most of the peaks arising at the onset of the photoelectron spectra. However, the small separation between these two ionic states makes vibronic interaction fairly inevitable. In the absence of Herzberg–Teller analyses for ionic states, we have sought and determined a transition state between the 12B2 and 12B1 states, showing that vibronic coupling does occur. The lack of degradation in the vibrational envelope of the higher of the two states contrasts with our previous work on the halogenobenzenes, where overlapping state envelopes led to considerable widening of the line width at half-height of the higher energy states.
Palmer , M H , Coreno , M , de Simone , M , Grazioli , C , Jones , N C , Hoffmann , S V , Aitken , R A & Sonecha , D K 2023 , ' The ionic and ground states of gamma-pyrone. The photoionization spectrum studied by synchrotron radiation, and interpreted by configuration interaction and density functional calculations ' , The Journal of Chemical Physics , vol. 158 , no. 1 , 014304 . https://doi.org/10.1063/5.0128764
The Journal of Chemical Physics
Copyright © 2022 Author(s). This work has been made available online in accordance with publisher policies or with permission. Permission for further reuse of this content should be sought from the publisher or the rights holder. This is the author created accepted manuscript following peer review and may differ slightly from the final published version. The final published version of this work is available at https://doi.org/10.1063/5.0128764.
Items in the St Andrews Research Repository are protected by copyright, with all rights reserved, unless otherwise indicated.

domain: literature


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text:
Ethics & Pedagogy
Overcoming Objectification: A Carnal Ethics
Ann J. Cahill
Objectification is a foundational concept in feminist theory, used to analyze such disparate social phenomena as sex work, representation of women's bodies, and sexual harassment. However, there has been an increasing trend among scholars of rejecting and re-evaluating the philosophical assumptions which underpin it. In this work, Cahill suggests an abandonment of the notion of objectification, on the basis of its dependence on a Kantian ideal of personhood. Such an ideal fails to recognize sufficiently the role the body plays in personhood, and thus results in an implicit vilification of the body and sexuality. The problem with the phenomena associated with objectification is not that they render women objects, and therefore not-persons, but rather that they construct feminine subjectivity and sexuality as wholly derivative of masculine subjectivity and sexuality. Women, in other words, are not objectified as much as they are derivatized, turned into a mere reflection or projection of the other. Cahill argues for an ethics of materiality based upon a recognition of difference, thus working toward an ethics of sexuality that is decidedly and simultaneously incarnate and intersubjective. Abstract retrieved from Psychology Press.
Cahill, Ann J. (2012). Overcoming objectification: A carnal ethics. New York, NY: Routledge.
“Our Hearts Are Collectively Breaking”: Teaching Survivors of Violence
Gender and Society, 3 (4): 541-548 (1989)
This article discusses teaching survivors of violence in an introductory women's studies course and addresses the pedagogical question of whether we are able to promote individual agency and empowerment effectively and, if so, how might we best go about it. Survivors spoke out in their journals and in the classroom about their experiences, shared feelings about empowerment, and assessed the ways and extent to which the course helped them to heal. I found that survivors benefited from being able to talk about their experiences and from being encouraged to place their personal experiences in a broader political context, but that a crucial component was the affirmation, validation, and solidarity they felt with each other in the classroom. Abstract retrieved from Sage Journals.
Lee, Janet (1989). “Our hearts are collectively breaking”: Teaching survivors of violence. Gender and Society, 3 (4): 541-548.
“Pleasure Has No Passport”: Re-visiting the Potential of Pleasure in Sexuality Education
Louisa Allen and Moira Carmody
Sex Education, 12 (4): 455-468 (2012)
The idea that pleasure might form a part of sexuality education is no longer a ‘new’ idea in the field of sexuality studies. In this paper we examine how originally conceived notions of pleasure have been ‘put to work’ and theoretically ‘taken up’ in relation to sexuality and education. It is our contention that because of the nature of discourse and varying cultural and political contexts, pleasure has been operationalised in ways we did not intend or foresee. Throughout this discussion we seek to discern the discursive limits of visions of pleasure to illuminate their normalising potential. Drawing on Foucault's thoughts about pleasure as having ‘no passport’ and queer theoretical understandings of this concept, we argue for a re-conceptualisation of the potential of pleasure in sexuality education. In particular we identify the need for wedging open spaces for the possibility of ethical pleasures, in forms that are not heteronormatively pre-conceived or mandatory. Abstract retrieved from ERIC Institute of Education Services.
Allen, Louisa and Carmody, Moira (2012). ‘Pleasure has no passport’: Re-visiting the potential of pleasure in sexuality education. Sex Education, 12 (4): 455-468.
Teaching about Violence Against Women
Feminist Press at CUNY (1999)
Violence against women is one of the most debated and challenging subjects in women's studies today. This special issue of Women's Studies Quarterly encapsulates recent debates and offers an invaluable framework for exploring its global context and for conveying these ideas to others. With contributions from distinguished scholars around the world, this volume considers not only the different cultural and political contexts of violence, but also the progress that has been made by women throughout the world in identifying and organizing against various forms of violence. By offering an increased understanding of violence in an international context and by celebrating successful instances of resistance, Teaching About Violence Against Women suggests innovative ways for teachers, students, activists, and crisis intervention specialists to think and to teach about this difficult, often painful, but crucial topic. Abstract retrieved from Google Books.
Eliasson, Mona (1999). Teaching about violence against women. New York: Feminist Press at CUNY.


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Waves of Wood
Timothy Davis specialises in the creation of unique woodwork pieces. As a self-taught woodworker, Tim takes pleasure in utilising locally sourced timber and complementing them with bio resin or lead-free metal to fill in any gaps. Each piece of art produced by Tim is unique, featuring individual flaws and qualities that cannot be duplicated. Tim draws inspiration from geological formations, river landscapes and coastal views. The golden ratio is also incorporated into every piece, as it can be observed in everything from DNA to rolling waves in the natural world.
The goods are handcrafted using only the finest components which are hand-selected to perform better than expected in the intended function. Timothy uses wood from Cambridgeshire, which was produced naturally with the plant in mind. All wood is obtained ethically and is not cultivated for commercial purposes. The bio resin is resin that has been improved. 30% of it is vegetable oil. Also lead-free pewter, the safest and most durable casting metal.

domain: design


How can I request more disk quota?#
If the current quota limits of your personal storage or Virtual Organization (VO) are not large enough to carry out your research project, it might be possible to increase them. This option depends on data storage policies of the site managing your VSC account, VO or Tier-1 project as well as on current capacity of the storage system.
Before requesting more storage, please check carefully the current data usage of your VSC account and identify which file system needs a larger quota.
Once you have identified the file system that needs the increase, follow the corresponding instructions to submit your request:


text:
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domain: economics


text:
Financial statementsAuditor reportManagement ReportManagement Discussion and AnalysisNotes of Financial DataSummary of Financial Data
Explain the users of annual report
what is pizza hut's annual report over the years
An example of an annual report would be income taxes for many people. An annual report is something that is completed only once during the course of a year.
The annual report of company is a information that receives a lot of attention. The annual report is very important document for every company to define their goals and forecasting.
chk max India annual report
A free annual credit report can be acquired from a website called Annual Credit Report. Contrary to popular belief, Free Credit Report does not always provide free credit reports.
An annual report is a comprehensive report on the activities of a company throughout the preceding year, generally produced in compliance with requirements established by government agencies.
One can obtain a free annual credit report from Experian by going on the site itself. After that, click Credit Report and insert your personal information for verification and they will provide you a free annual credit report.
The importance of annual report of company for the firm is huge you should good knowledge and skills in the annual report creation that contain company activities from the past year and it could bring you a lot of benefits if it's done in an effective and professional way. Annual report of company will help present your strategies and development to your company's shareholders. Annual report is also helpful to set realistic goals for the company.
to whom is a report disseminated to and how is it done
AnnualCreditReport is the only page that can legally show you your annual credit report, by authority of the FTC. This report is shown to you for free and belongs to you.
I think annual report means the whole report ( include work, progress, finance, development) after the end of year ( December) . Financial report means the financial report of 12 months which is submitted on 31st March.
Is an employ required to file only an annual tax report on an employer?
account means the property you have in the bank.for example,I have 900,000 shillings. annual report are report which are said once and repeated for example,In Kenya there are two annual report in the country.Like K.C.P.E and K.C.S.E by muadh In Kenya.
The balance sheet
An annual report
Unilever's 2008 Annual Report is a 165 page PDF document that can be found by asking a search engine to find "Unilever Annual Report 2008".
You can get an annual credit report from Equifax, Experian and Trans Union. As well, there are smaller companies and other sites where you can obtain your credit report.
Check with the Secretary of State of the state where the corporation or business is formed. Most states require an Annual Report and may charge a fee for this Annual Report.
A person can get their credit report score for free on an annual basis by applying online at a credit report site that will offer free credit reports. Someone can fill out a report online, or mail one to a business that offers free annual credit reports.
photograph-JPEG Memorandum-Microsoft Word template memoandum statistical report and a company annual report?
A company that is publicly owned is required to issue an annual report to stockholders. The annual report includes a wide variety of financial information and a discussion and analysis of operations by management. Many of the financial disclosures found in an annual report are required by regulatory bodies such as the Securities and Exchange Commission (SEC) and the Financial Accounting Standards Board (FASB). A typical annual report will contain sections on financial statements, letter to shareholders, footnotes to the financial statements, and an auditor's report.

domain: finance


Tommy Trash continues his unbelievable spree. Momentously releasing one monstrous track after another, all within a few weeks of each other, previews are just the cherry on top that keep listeners juices flowing for his next enormous release. As we said on WMHA , remixing is a fearless task for Tommy. Tracks like “One Last Ride,” “Falling Out of Love,” “Edge of Earth,” and “Alive,” are just a few examples to back that up. Even if it’s music that is already great, Trash often manages to make it even better. This time, Trash generously previews his remix to one of the biggest influences in the electronic music world—Moby. Tommy Trash’s remix to “After” maintains Moby’s dark classic melodies and vocals, yet is filled with Trash’s signature juicy bass lines, and filthy electro drops. The release is set for October 17th, which is excitingly right around the corner!
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The day has finally arrived: Coachella’s 2017 lineup is here, and as expected, it’s extraordinary. As previously confirmed, Radiohead, Kendrick Lamar, and Beyonce will headline the festival, with amazing sub-headliners like The xx, Bon Iver, Empire of the Sun, and
Ranking DJs is inherently confusing. As Dillon Francis pointed out on DJ Mag’s annual list, it’s never quite clear what criteria is being considered when compiling these lists. In an effort to clarify this process, we’ve decided to split our end-of-year artist rankings into


text: The US Congress is approaching its favorite time of year, August recess, when members flee the oppressive heat and humidity of Washington. Get ready, Israel, they are coming to a handshake near you.Congressional recess periods allow members to travel home to their communities or around the world. Although the latter are maligned as “junkets,” they are critical to informing judgments about global issues. Reading a briefing about the Iron Dome anti-missile defense system is one thing; seeing it in action is another. Attending a classified briefing about the wars in Iraq and Afghanistan is helpful to congressional decisions on funding the military, but going into the military theater and discussing it with the people doing the fighting is priceless.Israel is a popular destination for congressional travel, and not just for the photo ops and falafel. It is Congress (not the president) that appropriates funds, decides on levels of foreign military financing, and allocates money for Israel’s ballistic missile defense and other vital technologies. The House and Senate appropriations committees are considered two of the most powerful committees on Capitol Hill for a reason: They spend the money.As a member of the House Appropriations Committee, I visited Israel with my colleagues countless times. One of the most important was in the days immediately following Hamas’s rocket attacks in August 2014. We were the very first congressional delegation to arrive.Just a few days before, Congress had granted president Barack Obama’s emergency request for $225 million to help replenish Israel’s Iron Dome stockpiles. This wasn’t a vote to be taken lightly. There were deep economic anxieties at home; many American media outlets were reporting critical stories about Israel, and controversy was building over the Iran nuclear deal.Our visit included briefings on the effectiveness of Iron Dome. From the Golan Heights, we saw – without binoculars – plumes of smoke from rocket exchanges between rebel and government forces in Syria. We learned about the extensive network of tunnels penetrating Israel’s soil near the Gaza Strip.Every member of that congressional delegation returned home with a deeper understanding of Israel’s needs. In fact, that particular visit inspired me to work with Rep. Gwen Graham (D-Florida) to successfully secure $40m. in tunnel-detection technologies for Israel. Still, the most compelling congressional visit I made was soon after my 2000 election. I came on a trip organized for new members by the AIPAC Educational Foundation.Most of my colleagues had never been to Israel. They represented vast rural districts practically the size of Israel. Their preconceived notion was that yours is a big country that could afford to give up some land.One day, we traveled to a high point. Our guide pointed east at the mountains and said: “That’s the West Bank.” Then he pointed west at a distant and vaguely discernible skyline and said: “That’s Tel Aviv.” One of my colleagues said: “Well, how can we expect these people to give up land when you can see from one end of the country to the other? I can’t see from one end of my district to the other!” Putting aside individual views about the peace process, that visit offered a view of the terrain. On that congressional visit, as with all others, I learned the indispensable lesson of persuasion: Seeing is believing.The writer served in the US House of Representatives from 2001 to 2017 and was a member of the House Democratic Leadership. He currently serves as chairman of the Global Institute at Long Island University.


text:
World Rugby has confirmed it is investigating whether New Zealand managed to sneak an eighth player onto the field during their rugby sevens match in Sydney on Saturday, but say the result will stand.
Footage emerged of eight New Zealanders on the field while attacking Australia's line moments before Ardie Savea sank the hearts of the locals with a try after the full-time siren.
It meant Australia had to settle with a 17-17 draw and missed an opportunity to top Pool A.
Had referee Craig Joubert or his match officials noticed that New Zealand had an eighth player helping in attack, a penalty would have been awarded to Australia and all but secured a much-needed victory.
Instead, World Rugby say there will be no change to the result but a formal investigation will be launched to see whether there any punishment needs to be dished out to New Zealand for its infringement.
"World Rugby can confirm that it is investigating an apparent breach of Law 3 (number of players on the field if play) by the New Zealand sevens team," read a statement released on Sunday morning. "In accordance with Law 3.2 the result of the match will stand, but World Rugby is currently reviewing the matter to determine if any disciplinary action is warranted. No further comment will be made until the outcome of the investigation."
It means Australia will face off against England - as they had originally planned to do - in the quarter-finals on Sunday, but had the mishap been picked up by match officials, Australia could have had an easier last-eight clash with the USA.
A number of Australian fans vented their frustration on social media at the decision with some feeling they were harshly done by.


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text:
Floating-Harbor syndrome: description of a further patient, review of the literature, and suggestion of autosomal dominant inheritance
- Cite this article as:
- Lacombe, D., Patton, M.A., Elleau, C. et al. Eur J Pediatr (1995) 154: 658. doi:10.1007/BF02079072
The Floating-Harbor syndrome is a growth retardation syndrome with delayed bone age, speech development, and typical facial features. The face is triangular with deep-set eyes, long eyelashes, bulbous nose, wide columella, short philtrum, and thin lips. We present an additional patient and review 16 cases from the literature. The possible phenotype in the patient's mother suggests a dominant mode of inheritance for the syndrome.
The Floating Harbor syndrome is a growth deficiency syndrome characterized by proportionate short stature, characteristic face and delayed speech development. Inheritance is possibly autosomal dominant.
Key wordsFloating-Harbor syndrome Growth retardation Dysmorphology Genetics
Floating Harbor syndrome


text:
March 3, 2017
Eastern Kentucky University
Workshop Presentation & Handout
Educational discourse is highly structured, with predictable and repeated patterns through all grades and types of classroom activities. Interpreters need to have strong mental maps of these discourse types and be able to express them clearly through use of space and prosodic features in ASL. This workshop will use a combination of discussion and interactive activities to develop the knowledge and practice the skills that address the following challenges:
- What are the patterns of language in use in the classroom?
- What are the various options for use of space in ASL and how can they most effectively convey classroom content
- What is prosody and how can we represent English prosodic features in a visual form?
. Successful participants will be able to:
- To list at least 5 features of discourse maps;
- To compare and contrast texts (both ASL and English) with and without discourse mapping features;
- To practice the use of discourse mapping within a rehearsed interpretation.
Each of the titles in the list below is a link. When you click on the title, it will reveal a series of resources contained in that category.
Learning from Cognitive Science and Psychology
For the grant project that I am working with the CATIE Center on, this is a real focus for me now – looking at evidence-based practices for how we actually learn. Here are the two books that I am finding extremely helpful.
by Brown, Roediger, and McDaniel Published in 2014.
This books uses stories to illustrate evidence-based practices that help promote durable learning – that is things that last beyond regurgitating items for a test. Here are some of the principles that help learning last:
- Effective learning is effortful. (If it is easy, you probably won’t remember it for the long-term.)
- Effective learning is spaced out. (Waiting a week and then testing yourself to try to see if you remember the information – using techniques like flash cards to make yourself try to remember – and then checking to see if you did accurately.) It is the trying to remember that actually helps establish the neural pathways which allow you to retrieve information for use.
- Effective learning includes reflection, elaboration, and generation. Reflect: look back on what you studied and think of how it connects with what you already know; elaborate: make connections to other concepts you use and see how the ideas can be tied together into a mental model; and generate: imagine how you would apply the concepts in future scenarios.
- Effective learning uses dynamic assessment. This includes frequent and low-stakes assessment – like quizzes that both help you know where you stand and also force you to try to retrieve information. Research shows that this is much better time spent than re-reading or re-watching texts.
I really suggest that this is a book worth reading – to help you learn some powerful tools – and perhaps even more importantly, to be motivated to try some of these new techniques because research also shows that though they produce good results, people sometimes prefer what is familiar because it feels easier and gives the illusion of knowledge. You might feel like you are learning things more quickly using strategies like re-reading a text – but the reality is that it won’t stick.
by Daniel Kahneman. Published in 2011.
A book for the lay person by an economic psychologist and Nobel Prize laureate, Kahneman lays out many principles of how our brains work that have an impact on the way we learn. He uses a great number of examples for the two systems of our brain:
- System 1: Our automated brain that is the “thinking fast” part of how we deal with the world. This is a system designed to make connections, fit information into a cohesive narrative, and jump to conclusions. It also sometimes fools us and makes serious mistakes because of a number of biases that are built into the process.
- System 2: This is the part of our brain requiring conscious effort and is designed to be a check on system 1. This is the “thinking slow” part.
Kahneman lays out a number of psychological experiments that have demonstrated how these two systems interact and how we sometimes get caught up in thinking errors because we believe we are making decisions solely with our system 2, but that they are often influenced by our system 1.
Resources for Discourse Mapping
Discourse mapping is a term used for both the process of analyzing texts in interpreter education and skill development and the features of an interpretation that use linguistic features to create a connected and cohesive product. These resources are related to both doing the analysis and being able to create more effective discourse mapping in your work.
This is a packet that takes you through a step by step process for doing discourse analysis.
This video series features a Deaf woman and a hearing man talking about their experiences canoeing in the Boundary Waters Canoe Area Wilderness. There are 6 parallel talks in this topic in the following genres: narrative, procedural, explanatory, hortatory, and argumentative.
Miako Rankin, from Gallaudet University, did a workshop on Depiction that provides a good framework on how space is used, how classifiers are incorporated into that, and how depiction of action and conversation is an important framework for helping to understanding the mapping of space and discourse.
Videos for Discourse Mapping
A Source Text for Discourse Mapping Practice
Source Text with Processing Time
Translations without Mapping
To the best of our ability
Slavery and American Revolution
The original lecture
With Commentary on Fingerspelling & Discourse Mapping features
A High School Anatomy Lecture
Posted in: "Cartography for Interpreters" Resources, "TIPS-Light" Resources, Discourse Mapping, In Service to Literacy, Mentoring Resources, Moving toward Best Practice, Putting Theory into Practice, Sense of Place, Swiss Army Knife Tools
Thanks to the organizations who helped to make this workshop possible.

domain: psychology


text:
n by Norwegian, the inflight magazine for Norwegian Air Shuttle, won the Best Inflight Publication Award at the APEX Passenger Choice Awards this week at a glitzy ceremony which took place at the APEX EXPO in Portland on Monday 27th September.
Published by Ink, n by Norwegian, beat off competition from Avianca S.A, Ethiopian Airlines, Garuda Indonesia and SriLankan Airlines.
Toby Skinner Editor of n by Norwegian said: “It’s really nice to get recognition in international awards, but especially when it’s voted for by passengers. We often talk about fancy ideas and concepts, but in the end it doesn’t mean anything if the average passenger doesn’t pick up the magazine and enjoy it.”
In addition, Norwegian were recognised with an award for The Best in Region (Europe).
The Passenger Choice Awards were created by Airline Passenger Experience Association to give a voice to the travelling public and to recognise airline excellence and innovation.
For a full list of winners click here.
8th October 2020


text:
The Dead of Winter
- Lee Collins
Publisher: Angry Robot
E-Arc Courtesy of Netgalley & Angry Robot
Cora and her husband hunt things - things that shouldn't exist. When the marshal of Leadville, Colorado, comes across a pair of mysterious deaths, he turns to Cora to find the creature responsible, but if Cora is to overcome the unnatural tide threatening to consume the small town, she must first confront her own tragic past as well as her present
Cora is a gun-slinging Buffy-esque character. She and her husband, Ben roam the Wild West taking care of monsters, beasts and vampires who are terrorising towns. Ben is more the book type while Cora is happy to shoot first and ask questions second – if at all. I really like Cora’s brash no-nonsense manner and her hard drinking, gambling ways. She was a hard woman with a short temper. It would be easy to dislike her but her relationships with the priest and her husband showed she has heart and some softness to her underneath all the bluster.
A lot of the town could be seen a stereotypes – the deputy in love with one of the local call girls, the weary aged sheriff, the smug book learned British snob, and while they all felt familiar, there was a spark in each of them that made me feel like they were real. However, this is a book less focussed on character and all about the action. It feels very much like this could be the start of a series and even reads like a two-parter complete with a distinct finish half way through that has enough threads wrapped up that you’d happy, but some elements which drive the second, more personal part. I loved some of the tense scenes with the walk through the mines or the fight in the town with the creatures – it was very visual and exciting.
An exciting action-packed adventure which adds vampires and creatures to the Wild West and let’s rip! The Magnificent Seven crossed with Buffy, this is very a much read for those who want more action and less angst in their Vampire and Monster Slaying. It really makes me wonder why no-one has tried mixing up the genres like this before...or if they have, I’ve missed it. I really hope there is another book featuring Cora as there is some real potential – plus the Western genre has not appealed to me up to now!
Recommended for fans of Matthew Reilly and Jim Butcher. 8 out of 10


LA PAZ – Bolivia’s President Evo Morales confirmed on Thursday that he will seek what would be a fourth consecutive term in office in elections scheduled for 2019.
In a speech in the central region of Cochabamba, Morales said US threats and interference in the Andean nation’s internal affairs had been the catalyst for his decision.
“I wasn’t that certain. Now I am. I’ll be a candidate in 2019,” the leftist head of state said.
The US State Department on Wednesday expressed concern over this week’s Constitutional Tribunal ruling that found that constitutionally mandated term limits for the president and other officeholders violate Article 23 of the Inter-American Convention on Human Rights.
The court found in favor of a motion brought by the governing MAS party challenging several articles of the constitution and provisions of the electoral law.
Under the 2009 constitution enacted by Morales, the president is limited to two consecutive terms.
The US State Department said Tuesday’s ruling disregarded the will of the Bolivian people, noting that they had voted in a referendum to approve the 2009 constitution and that in a February 2016 plebiscite they had rejected Morales’ bid to amend the constitution to allow him to run for re-election once again in 2019.
Morales and Vice President Alvaro Garcia Linera started their first term in 2006, their second in 2010 and their third in 2015. They were allowed to seek a third mandate thanks to a ruling by the Constitutional Tribunal that the adoption of the new national charter in 2009 re-set the clock on terms in office.
A fourth term would extend Morales’ tenure to 2025.


text: We also provide fixed denture work for our patients. This is what we call crowns and bridges in the dental profession. We do both the gold substructure crowns as well as full porcelain. We also do implant crowns with the Mini Dental Implant system. An exam is required to determine your need for these services.

domain: medical


text:
Running After David (Birds of Prey 2)
Ever since David learned about the war between the Birds of Prey and Blood Demons, he has longed for the Birds of Prey leader, Night. When the warrior rejects him, David leaves to forget the world he was thrust into. Night was created for one purpose, to fight in a war between good and evil. When his Goddess Athena gives him the gift of a mate, Night doesn’t know how to care for the man meant for him. Will Night learn how to love the David, and will he get to him in time to protect him?


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text:
How do babies and dogs get along harmoniously?
For babies, there are many benefits when pets are around them, and interacting with pets helps with kids' social and emotional development.
But no matter how well you think you know your pet, or how gentle they may seem, it may be a potential danger to babies. Animals are our friends, but even friends can get angry. Even adults can get hurt by animals at any time, not to mention babies who are unable to distinguish between toys and animals.
Many families may give up keeping pets after having a baby. In fact, babies and pets can get along, but there are a few caveats. This article will show you how to get along with your baby and pet.
If you want to have a pet after you have a baby
In general, try to contact the baby and pet and become friends until the baby is old enough to take care of the pet. The age for a child to have a pet companion is over 5 years old when the baby is old enough to take care of a pet. But if you already have a pet, wait until your baby understands what "no" means. Pay attention not to let children and pets have competitive sense, parents should pay more attention to children. Otherwise, the baby may feel left out.
Choose a gentle pet
Older ones are generally safer than newborns, and smaller ones are better than larger ones because they are less likely to harm the baby.
Keep your pet clean
Pets tend to have more bacteria if they are dirty. Babies are vulnerable to infection from pets. So with pets and children at home, it's important to keep your home clean and tidy.
Regularly take the pet to the hospital for a physical examination, inject the vaccine, but also clean the pet thoroughly and remove mites. To prevent babies and pets from too close contact, it is best not to let pets lick the baby, especially the baby's face, hands, and wounds, to prevent the spread of the virus.
Wash your pet with a disinfectant bath, wash your pet's hair, and trim their nails to prevent the baby from sucking the hair or getting hurt by the pet's nails. Wash your baby's hands after touching pets. Prepare gauze, iodine, and alcohol at home in case of need.
Train your pet in healthy habits
Pet excreta is very unsanitary, must not let the baby be touched, and should be cleaned up in time. Pet's nest and cutlery should be cleaned in time because when babies start to crawl and walk, they like to run around the house. So you should pay attention to the handling of pet waste and clean pet dishes to avoid bacterial growth. Be sure to keep the room well ventilated and open Windows for at least two hours a day.
Keep pets out of the baby's room
The baby's living environment is very important. Although many owners clean their pets thoroughly, it can be difficult to get rid of parasites. Letting a pet into a baby's room can often fill it with germs, so keep it out of it.
Be prepared before baby and pet meet
Pets can be hostile to new members of the family at first. Take baby clothes home in advance to familiarize the pet with the smell of the baby, so the pet won't be sensitive to strangers when the baby comes home. Never leave pets and babies alone at home. Pets and humans need two to three weeks of familiarity, no matter how friendly they may seem at first, parents should always be there to protect their babies from harm.
Be alert! Babies are far less aware of the dangers
Give pet a space of its own
Gradually, the baby will climb and began to tear with his hands, with teeth to bite things. Parents should be vigilant at this time! Pets are used to the baby lying on the bed all the time, and changes in the baby's mobility can make it feel threatened, fearful, and likely to attack. Parents should pay special attention to this time, to let the baby away from pets. Give your pet a space of its own and don't let it wander around the house. Let your pet accept your baby's changes slowly, and let them get to know each other better.
Not to leave your pet and baby alone at home
Babies are too young to be dangerous and will irritate and injure their pets by pulling and scratching their ears or tails. So when the baby is learning to crawl, there must be parental care. To avoid safety risks, do not let children disturb your pet while it is eating or sleeping.
It is important not to leave your pet and baby alone at home. It takes about two to three weeks for a pet to get used to a human, and the parent should always be there to protect the baby from harm.
In all, spending time with pets at an early age can help develop empathy, responsibility, and social skills, as well as teach babies that animals smaller than themselves need to be cared for. In this process, your baby will learn the value of companionship and will no longer be self-centered. As long as parents play a good role in guidance, it is believed that babies and their pet partners will be happy!

domain: pet


text:
Phoksundo Lake Trek
Phoksundo Trek is a popular trekking route located in the Dolpo region of Nepal. The trek is named after the stunning Phoksundo Lake, which is the deepest lake in Nepal and is renowned for its crystal-clear turquoise water. The trek offers stunning views of the Himalayas, rugged landscapes, deep gorges, and traditional villages.
The trek usually takes around 10-14 days to complete and covers a distance of about 85 km. The trek starts from the town of Juphal and follows the trail along the Bheri River. Along the way, you will pass through several traditional villages such as Dunai, Tarakot, and Ringmo, where you can experience the unique culture and lifestyle of the local people.
The highlight of the trek is the visit to Phoksundo Lake, which is located in the Shey Phoksundo National Park. The park is home to a variety of wildlife, including the endangered snow leopard, Himalayan black bear, and musk deer. The lake is surrounded by snow-capped peaks and forests of pine, cedar, and birch.

domain: geography