The souvenir store
An original creation by artist Roberts Ruran for the 2023 edition of the festival, both a nod to the past and a dreamlike vision inspired by chapiteau and its magical mountains.
Seven exceptional tracks echoing the greatest live moments of these 10 editions of Radio Meuh Circus... A golden record for your turntables!
Since Mambo caught our eye, we asked him to do the poster... And he did! It's time to (re)make the wall, and the eyes of the Circus...
For those nostalgic for last year's trippy, shamanic visuals, artist Sophy Hollington is bringing out some rare copies of her displayed quadriptych!
Perched in the mountains of La Clusaz and connected to its independent webradio, the Radio Meuh Circus Festival is above all an opportunity to discover quality artists in a warm and relaxed atmosphere, all at the foot of the summits.


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What if is an original piece I made that depicts legendary boxer Muhammad Ali fighting legendary martial artist Bruce Lee in a fight that never happened. It begs the question, what if these 2 men faught? Who would win, how would they fight, who would be faster, who would hit harder. The world will never know which keeps this mystery alive.
Muhammad Ali vs Bruce Lee- What if this happened

domain: entertainment


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President William Ruto has signed the controversial Affordable Housing Bill into law.
The Head of State appended his signature on the bill at State House, Nairobi on Tuesday, paving way for the return of the unwelcome housing levy deductions.
Both the Senate and the National Assembly passed the bill last week with several amendments including bringing county governments to the fold.
All employers and employees will remit a deduction of 1.5% from their monthly salaries further puncturing the citizens’ pockets.
The levy had been declared unconstitutional by the High Court in 2023 and then the Court of Appeal upheld the decision maintaining that the levy was introduced without a legal framework.
Ruto’s government has however maintained that the suspension provided room for restructuring the bill and now provides a new legal framework for the levy.
The bill establishes four components of Affordable Housing.
They include the Social Housing Unit for persons earning less than Ksh.20,000, Middle Class for people earning above Ksh.49,000, General Affordable Housing for those earning between Ksh.20,000 to Ksh.149,000 and Rural Housing for those living outside urban areas.
Some of the institutions that will be mandated with implementing the Housing project include the Ministry of Housing, National Housing Corporation (NHC), County governments and Private entities as approved by the fund’s management body; the Affordable Housing Board.
The bill also noted that priority will be afforded to slum areas in constructing the affordable houses and also to ensure there is no multiple allocation of housing units.
Construction materials will also be sourced from local manufacturers and labour sourced from local communities.

domain: sociology


text:
Joe being Joe.
ZIP | June 15, 2012 1:40 pm
His last name is pronounced “asshole”.
The empty ones or the ones where people are jumping off the top story to commit suicide?
There new cities are ghost towns.
wait- Neil Kinnock never talked about Chinese cities… where is joey the ice kreem fiend getting these lines?
That’s because of a three-letter word: J.O.B.S. Jobs.
And our abortion policy is nothing compared to China’s either.
Do you mean these great cities, Plugs?
BTW: Dementia is not very becoming in the public arena.
Scratch a democrat, find a commie.
We could build great cities too except that the Republicans won’t tax the rich because they hate the poor. Everybody knows that great cities aren’t built by the private sector. Only the government can build great cities but not in places where there are Republicans because Republicans hate the poor. Or maybe the rich hate the poor. I forget. But we can’t build great cities here because somebody hates the poor.
This guy has always been a stupid communist preak
Do any of them have as big of a village retard as Scranton did?
How many of those new cities have people living in them?
Next Biden announcement: China way ahead of us on abortion rights.
How about he and all the other little marxists move there. We’ll pay,as long as they promise to stay there
Is he talking about the big empty “ghost cities”?
China, China, China…sounds like “Marcia, Marcia, Marcia..” yada yada yada
All thanks to BJ Clinton and obomb-a for passing those FREE trade agreements!
Joe, These cities are like the inside of your head, empty.
Not just China, all over the world they are building great buildings, great cities. We no longer have the tallest buildings, they are elsewhere. Government restrictions and environmentalist in this country are forcing great architecture offshore.
Joe Biden: Empty Head, Empty Suit,Cheap Skinflint.
Benefit to the RNC = Priceless
The RNC needs to start taking these Dims’ statements and speeches and creating videos to run everywhere. Not to mention howling aloud about Zero’s executive tyrannical orders… Use some of that 100 mil to pay for it.
The man is a total POS.
Building,building,building up their cities ruining the enviroment and these worthless idiots from GREENPEACE dont say a thing
Sounds like those cities are empty, just like Old Joke’s head!
Just imagine the fantastic cities Obama and Biden could build if only they had absolute power.
So Joe, when you move to China which two of your three children will you have aborted?
Well if we didn’t give all the tax payers dollars to countries that hate the USA we could have everyone in America out of debt and living high in beautiful cities. Its that constant borrowing from China to pay the dues for millions of dollars to the obsolete United Nations. They don’t account to us how any of that billions was spent for over 65 years. They are unsustainable. All the others NATO and the countries that hate us still getting millions and this needs to stop so we can take better care of our own. America will do okay once it straightens out this financial and moral mess that its in.
He should definitely keep talking-for obvious reasons.
Perhaps he should request to be buried in one…if their Cities are so great…their cemetaries must be fantastic!

domain: geography


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"Light and Music Relight Your Heart"
The combination of sound and light, as with the fusion of music and spotlights on a stage, evokes feelings of excitement. For all of us, light and sound serves both a functional and emotional purpose.
Since 2013, Yamaha has been producing a series of Interior Audio called "Relit" , with this concept in mind. In this exhibition, Yamaha will revisit the attraction of the series, through a collaborative project with Tord Boontje using 14 units of prototypes based on the LSX-70 and LSX-170.
Tord Boontje has crossed the boarders of pragmatism and aesthetics with ease, as he continues to release new products that unify beauty and function. He works with international companies on a range of mass productions, as well as one-off pieces; from lighting, furniture and textiles, to site specific installations.
Whilst keeping the lighting function and 360 degree sound system the same, Boontje's design approach puts forth a new perception of the beauty between industrial products and crafts, in line with the theme for this collaboration: "What is the perfect design for the fusion of light and sound?"
"Studio Tord Boontje has transformed these industrially produced speakers in to handcrafted objects. This approach to technology stems from the studio's desire to make everyday objects warm, characterful and materially interesting."says Boontje.
A kinetic 12.2ch soundscape, exclusively composed by sonic artist Manabu Shimada, will be played using the 14 speakers from the 18th to 20th November. This composition consists of two parts, a musique concrète soundscape using Yamaha field recordings, and a postmodern minimal music for piano and string quartet, inspired by the material of Hairy Creature Speakers.
Courtesy of Tracey Neuls, Yamaha Design Studio London will hold this exhibition at Tracey Neuls Marylebone. The speakers will be exhibited alongside distinctive shoes handmade by skilled craftspeople, with carefully chosen materials.

domain: design


text:
Cell lysates of 293T (50 ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with UBE2S monoclonal antibody, clone AT2C12 (Cat # MAB7885) (1 : 250). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
Immunofluorescence of human HeLa cells stained with Phalloidin-TRITC (Red) for Actin staining and UBE2S monoclonal antibody, clone AT2C12 (Cat # MAB7885) (1 : 500) with Alexa 488 (Green).
This gene encodes a member of the ubiquitin-conjugating enzyme family. The encoded protein is able to form a thiol ester linkage with ubiquitin in a ubiquitin activating enzyme-dependent manner, a characteristic property of ubiquitin carrier proteins. [provided by RefSeq
ubiquitin carrier protein S,ubiquitin-conjugating enzyme E2-24 kD,ubiquitin-protein ligase S

domain: medical


text:
21 January 2019, 20:42:
A group of the 7 Summits Club headed by Andrey Podolyan made a trip to Nepal, with climbing to the top of Lobuche and Ama-Dablam. They took the filming of the video very seriously. That was made a great movie. If we can get better through the normal campaign?


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Maratha reservation: Bombay High Court to hear batch of petitions today
Mumbai, Nov 21: The Bombay High Court on Wednesday will hear a batch of petitions on the issue of Maratha reservation. The Court has also asked the state govt to file a response with the state backward commission report.
The hearing came after the Maharashtra Cabinet on Sunday approved reservation to Marathas for which the community has been protesting since 2017, demanding quota in government jobs and in admissions in the academic institution.
The Backward Class Commission had been asked to prepare a report on social and economic backwardness of the Maratha community after pressure on the government increased. Marathas have been demanding 16 percent quota in in jobs and educational institutes.
In 2014, the then ruling Congress-NCP government had granted 16 per cent reservation for the Marathas and five per cent quota for the Muslim community just before the elections. However, the reservation was stayed by the Bombay High Court.

domain: law


text:
Researchers: Don't expand virtual schools as is
New research released Thursday suggests that efforts to quickly ramp up online “virtual” public schools nationwide could have a downside: lower achievement for the students who most need a boost.
Researchers from New York University (NYU) and the Rand Corp. looked at achievement for the nearly 1.7 million students in Ohio who attend K-12 virtual schools, which deliver most or all of their instruction online. They found that lower-income, lower-achieving white students are more likely to choose these schools than other students. Once enrolled, however, students in virtual schools are still performing worse on standardized tests than students in traditional brick-and-mortar public or charter schools.
The online charter school system in Ohio “tends to attract kids who are lower-performing, on average,” said Andrew McEachin, a policy researcher at Rand.
Many of these students are former home-schoolers or rural students looking for better schools. Others are looking for more flexible schedules, have gotten in trouble at school or simply don’t do well in school for many reasons — everything from lousy instruction to bullying.
“It could be a good alternative system for them, theoretically, and I think it’s worth figuring out why these individuals and their families opted out of a traditional brick-and-mortar school,” McEachin said. Parents “are sending a strong signal — at least a small group of them — that there is something (in) traditional brick-and-mortar-type schools that isn’t satisfying them.”
But his fellow researcher, NYU’s June Ahn, said these students need more support, not less. Nonetheless, many virtual schools “just put them in front of content with no social support,” he said. So it isn’t surprising that they get disappointing results.
“I’m not sure that the instructional design and the instructional environments of online schools right now are mature enough yet to handle young children at different stages of their development,” Ahn said.
Ready or not, virtual schools may soon be put to the test: on the campaign trail last September, candidate Donald Trump floated a plan to expand school choice rapidly by handing 11 million low-income children $12,000 apiece in public funds to attend the public, magnet, charter or private school of their choice.
The proposed federal contribution would equal $20 billion, more than the federal government spends each year to educate virtually all of the low-income children in public schools.
Betsy DeVos, Trump’s new education secretary, has championed virtual charter schools in her home state of Michigan and elsewhere. In financial disclosures, her husband, Dick DeVos, a 2006 GOP candidate for governor, revealed that the couple were investors in K12, a Virginia-based online education company.
During her confirmation process last month, DeVos told lawmakers that many virtual schools boast high graduation rates. Actually, many of these schools have fairly low graduation rates, previous research has shown.
But even if Trump showers the charter sector with billions in federal funding, Ahn said educators should “tinker in a more focused way” than simply opening up millions more seats. “I’m not sure you want to expand things really rapidly until you’ve got a little bit of a better idea of how to do it well.”
McEachin added: “As the evidence stands right now, it would probably not be a good idea to expand the current model further.”
The pair suggested that the government create a research-and-development fund to focus on how virtual schools can do a better job offering specialized coursework — for example, online statistics classes for rural students whose schools can’t offer them.
“But I think the design for a full day, or a full online environment, has not been shown to be very successful in its current implementation,” McEachin said. “If you just allow unfettered growth and fund unfettered growth, it’s highly unlikely to expect positive outcomes.”
The study appears in the new issue of Educational Researcher.
Follow Greg Toppo on Twitter: @gtoppo


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Ricochet is the best place on the internet to discuss the issues of the day, either through commenting on posts or writing your own for our active and dynamic community in a fully moderated environment. In addition, the Ricochet Audio Network offers over 50 original podcasts with new episodes released every day.
While on the way from one place to another, @stad and @neutralobserver happened to be passing through beautiful downtown Troy, Michigan, so we got together for lunch. It’s a nice way to have a meet-up. It’s a chance to just talk and get to know people. I learned several things:
- Stad writes under a pseudonym. It is not a masculine name, which led to my questioning if he were writing romance novels.
- He’s about to start writing romance novels, but no, had not in the past. (I never got around to admitting that I have one of those started, too, because why not?)
- He’s much taller than he looks in his avatar.
- Neutral Observer makes the worlds best burritos. I have Stad’s assurance of this. He even started detailing the process at one point, but I doubt I’ll get them to put the recipe in the You Will Need Group.
- “Cell phone photos are today’s equivalent of relatives carrying around a carousel of slides from the old days.”
- Once you retire, you have no time to fool around anymore, because there is just too much to do with life.
- Neutral Observer has picked up a soft, Southern dialect from living in the South, but no, she’s from out west.
I’m sure the huge, mega-meet-ups are a lot of fun, but I’ll take the opportunity to talk with you one-on-one(ish), if you happen to be in town.Published in

domain: hobby


text:
Sport and recreation administration graduate student Kyle Fluker will receive a National Association of Collegiate Marketing Administrators Mike Cleary Stipend. One of 30 recipients, he will use the award to travel to attend June’s NACMA Convention in Las Vegas.
The Flint, Michigan, native will network with intercollegiate athletics professionals from across the country, including those who work in marketing, tickets, development, and administration. Fluker is set to graduate in May and wants to continue working in college athletics.
“I’ve always been a big fan [of college athletics],” Fluker said. “I like the college experience … college fans are way more passionate.”
Fluker is completing a graduate assistantship in marketing with the SDSU athletic department. He creates graphics, manages interns and helps create an in-game atmosphere for Jackrabbits fans.
“I add fun pieces that engage our fans and get them excited to go to the games. Our fans are a different breed. They will try to make a relationship with you,” Fluker said.
Since starting in August 2018, Fluker has worked countless events, including when ESPN’s College GameDay broadcast visited Brookings and his first Jackrabbits wrestling dual.
“The energy at a wrestling dual is like no other,” Fluker said. “The fans make this sport what it is.”
In class, Fluker said assistant professor Bryan Romsa has taught several facets of the business side of sports.
“He opened my eyes to new ways of thinking, like the ethical side of sports, and what other teams and other people are doing to get people to games,” he said.
The sport and recreation administration graduate curriculum is focused on sport management, marketing, communications, facilities, finance, ethics and legal issues and research.
Marketing interests Fluker the most. He would like to work at a larger Division I university that has tennis, golf, basketball and wrestling. While Fluker is looking to leave the Midwest, he has enjoyed his time and his hands-on experience at South Dakota State University.
“Brookings has that community feel, I’ve never seen a university and a town being so hand-in-hand … There’s something special about this place.”

domain: news


MODEL REVITALISASI KAWASAN KOTA LAMA DITINJAU DARI ASPEK KEPARIWISATAAN UNTUK MEMACU DAYA TARIK WISATA DAN MENUMBUHKEMBANGKAN WISATA BUDAYA - SEJARAH: KASUS DI SEMARANG, JAWA TENGAH
Adi, Suyatmin Waskito
MetadataShow full item record
The research focuses on the analysis of the old city existence related to tourism and on how the old city existence as one of the destinations in Semarang. The data were primary and secondary. The analysis of the data focused on the observation of the old city characteristics associated with historical, existent and socio-economic and culture role or function; thus, the analysis used a qualitative approach. It could be concluded that the old city needs a revitalization program, primarily related to the old city existence historically. The research is limited to 1) the research approach focused on tourism, but not archeology – architectural; 2) research orientation focused on economic approach; and 3) the analysis not referred to synergy with other aspects. The results of the FGD stated that the existence of the Management Agency of Old City Area (BPK2L) is one of the important aspects to manage the city. The problem is related to ownership legality. Identifying the ownership is said to be a priority for supporting conservation – revitalization of the Semarang Old City. The other problem is associated with funding. It is close to visiting tourists continually. The findings showed that there are three aspects in relation to the revitalization of the Old City, namely maintenance, preservation and utilization. For this, building a synergy among three industries - related, core and supporting industries - in the circumstance of Old City is very essential because of the macro implication. The findings also indicated that the Old City area is strategically and characteristically macro so that it is necessary to optimize primary and secondary elements. The tow must be supported with a short- and long-action having an impact on revitalization agenda affecting and tourists’ image and visit.


Not every parent wants another tax increase this year to protect schools from massive layoffs, and some childless homeowners say they will vote for the $2.8 Proposition 2 1/2 tax override question that will go before voters June 10.
Residents interviewed at random yesterday had mixed feelings about the override Town Council recently voted to put on a ballot.
"I say, for the schools, for the kids, I would be for it. I don't have kids, but I've been in town my whole life," resident Mike Ficco said yesterday.
"I've watched the town succeed since I was a little kid. Franklin is going in the right direction," said Ficco, adding that he is willing to pay more in taxes to ensure it doesn't go in the wrong direction, as he has noticed in other towns.
Read the full article in the Milford Daily News here


text:
Der Berliner (Hannes) asked me if I could be the photographer of Istanbul FACITY.
I said OK.
Wait for us.
Dear airlines could you please send me back to London? I wanna be sacrificed in Russel Square again, where I started smoking.
Upper photo is from dA, the below is mine, taken in 2007, Camden Town.

domain: artistic


In the times main as much as that tragedy, there were new legislative initiatives being mentioned in Congress round privateness, a few of which might nicely have outlawed practices that turned routine operations of surveillance capitalism. A federal appeals court docket panel on Friday allowed President Joe Biden’s COVID-19 vaccine mandate for larger private employers to maneuver forward, reversing a earlier determination on a requirement that may affect some eighty four million U.S employees. The hidden charges found in automobile insurance policies have soared in the final five years, with practically half together with a ‘set-up’ fee of as a lot as £60.
We compiled a list of some of the most revolutionary presents out there, ranging from tech-driven fashion to ethical wellness products. The finest merchandise, providers, interfaces, and design ideas in business. Automotive business consultants fear 2022’s recovery might be limited by the global shift to 5G network. The newest Westpac Regional Roundup report reveals the emergence of the Delta variant created a performance hole between areas that had fewer restrictions, and people who had been compelled into lockdown. The Reserve Bank has made three appointments to its government leadership staff, following the resignation and retirement of a number of members.
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The new six-part Audible Original Christmas Delivery written and directed by UCB alum Achilles Stamatelaky and starring comedian actors Gillian Jacobs and Sam Richardson is a model new spin on Charles Dicken’s A Christmas Carol price ho-ho-hoing to. It is a precedence for CBC to create a website that’s accessible to all Canadians together with individuals with visible, hearing, motor and cognitive challenges. The 30-year fixed-rate common ticked as a lot as 3.12 % this week. MRNA vaccine maker says it needs to ‘avoid any distraction’ in omicron fight. Some South Korean millennials told Insider that having no sensible means to repay staggering debt is a real and grim reality in cities like Seoul. Meghan McCain shared details about her 2019 miscarriage in her new audio memoir, “Bad Republican,” which debuted on Audible.
Omicron Rising: Virologist Calls For Covid
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Things could worsen earlier than they get higher this holiday season according to Dr. Willie Belton, an economist from the Georgia Institute of Technology. When the clock strikes midnight on December 31, one in five massive companies will likely fail to comply to their legal obligations beneath Australia’s Modern Slavery Act , based on new analysis from the University of South Australia. But extra considerably, the estimated financial misery of for-profit hospitals elevated to 39.1 % through the tumultuous year of the coronavirus outbreak – about seven percentage factors higher than in 2019. Businesses and venues that implement a proof of vaccination requirement must be positive that anybody 12 years of age or older is totally vaccinated earlier than entering indoors. Businesses/venues can acceptExcelsior Pass,Excelsior Pass Plus, SMART Health Cards issued outside of New York State, full-course vaccination throughNYC COVID Safe app, a CDC Vaccination Card, or different official immunization document.
Introducing a daring, new search for Businessweek together with issue downloading for offline reading. Our Covid-free publication brings together a number of the greatest bits from irishexaminer.com, as chosen by our editor, direct to your inbox every Monday. See right now’s front and back pages, download the newspaper, order again issues and use the historic Daily Express newspaper archive. PIP claimants could qualify for car tax exemptions – can you cut back your prices by half?
So from the beginning the logic reflected the social relations of the one-way mirror. They had been able to see and to take — and to do that in a method that we could not contest as a result of we had no method to know what was taking Finance place. The persevering with advances of the digital revolution could be dazzling. But Shoshana Zuboff, professor emeritaat Harvard Business School, warns that their lights, bells, and whistles have made us blind and deaf to the methods high-tech giants exploit our private data for their own ends.
Gov. Daniel J. McKee is reinstituting a partial indoor mask mandate that makes them necessary in large venues but optional for small companies, which… Shares opened below $100 for the first time, dipped to $92.sixty two in early trading, and have been still off 11% within the afternoon. Herb Washington owned over a dozen US restaurants when he claimed the company treated white owners more favourably.
Banks, Incitec Defend Local Weather Credentials
SHANGHAI, Dec 17 — Chinese drone-maker DJI is easily the highest-profile company targeted in a new round of US economic sanctions against companies over China’s therapy of… JAKARTA, Dec 17 — The World Bank projected Indonesia’s financial system to recover at a average tempo of 3.7 per cent in 2021 due to the Covid-19 Delta variant wave mid-year. LONDON, Dec 17 — British retail gross sales accelerated final month, boosted by heavy pre-Christmas Black Friday discounting prior to the arrival of the Omicron coronavirus variant,… PARIS, Dec 17 — Europe’s car industry is dealing with a worse year than the Covid-battered 2020 with sales falling a fifth straight month amid a global scarcity of digital…


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text:
Currently, there is no effective pharmacologic therapy against ARDS because of insufficient knowledge of the pathogenesis mechanisms. The overarching focus of the P01 is on mechanisms of pulmonary responses to a new pulmonary toxin and regulator, the anionic phosholipid, cardiolipin (CL) originating from bacteria or mitochondria of damaged host cells during acute lung injury. Thus elucidation of novel metabolic and biochemical pathways of different molecular species of CL, its metabolites and their interactions with other pulmonary lipids and their peroxidation products are fundamental to all four projects of the P01. The Oxidative Lipidomics Core (Core B) has been designed to allow researchers in the projects to perform detailed analysis - identification, characterization and imaging - of all major molecular species of Cls, other different classes of lipids as well as their oxidation products. This will be achieved by using sophisticated state-of-the art techniques based on different versions of mass-spectrometry (MS) combined with liquid? chromatography (LC) or high-performance thin-layer chromatography (HPTLC) protocols.
Specific Aims of the Oxidative Lipidomics Core B are to: 1. Provide professional expertise in the design and implementation of experiments using adequate techniques for identification, characterization, and quantification of lipids, particularly Cls. Prepare and optimally analyze samples to detect individual molecular species of lipids and oxidized lipids. 2. Provide opportunities for mass-spectrometric imaging of different types of individual molecular species and oxidized lipids in lung tissues. 3. Evaluate experimental results and propose subsequent experimental direction. 4. Provide training in the use of and access to any instrumentations and techniques used within the P01 project to assess lipidomics/oxidative lipidomics biomarkers. By assisting the Projects in the analytical work, the Core will facilitate studies of the mechanisms through which CL functions as a new molecular signal in acute lung injury hence contributes to the development of new therapeutic modalities.
The goal of this PPG is to characterize a newly discovered damage signal, cardiolipin (CL), in acute lung injury, The Oxidative Lipidomics Core will perform state-of-the art analysis of all major molecular species of Cls in pulmonary cells and lung tissue. The analytical work of the Core will facilitate the discovery of the new mechanisms of acute lung injury hence contribute to the development of innovative therapeutic modalities
|Suber, Tomeka L; Nikolli, Ina; O'Brien, Michael E et al. (2018) FBXO17 promotes cell proliferation through activation of Akt in lung adenocarcinoma cells. Respir Res 19:206|
|Kitsios, Georgios D; Fitch, Adam; Manatakis, Dimitris V et al. (2018) Respiratory Microbiome Profiling for Etiologic Diagnosis of Pneumonia in Mechanically Ventilated Patients. Front Microbiol 9:1413|
|Chao, Honglu; Anthonymuthu, Tamil S; Kenny, Elizabeth M et al. (2018) Disentangling oxidation/hydrolysis reactions of brain mitochondrial cardiolipins in pathogenesis of traumatic injury. JCI Insight 3:|
|Kitsios, Georgios D; McVerry, Bryan J (2018) Host-Microbiome Interactions in the Subglottic Space. Bacteria Ante Portas! Am J Respir Crit Care Med 198:294-297|
|Lou, Wenjia; Ting, Hsiu-Chi; Reynolds, Christian A et al. (2018) Genetic re-engineering of polyunsaturated phospholipid profile of Saccharomyces cerevisiae identifies a novel role for Cld1 in mitigating the effects of cardiolipin peroxidation. Biochim Biophys Acta Mol Cell Biol Lipids 1863:1354-1368|
|Anthonymuthu, Tamil S; Kenny, Elizabeth M; Lamade, Andrew M et al. (2018) Oxidized phospholipid signaling in traumatic brain injury. Free Radic Biol Med 124:493-503|
|Hassannia, Behrouz; Wiernicki, Bartosz; Ingold, Irina et al. (2018) Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma. J Clin Invest 128:3341-3355|
|Meiners, Silke; Evankovich, John; Mallampalli, Rama K (2018) The ubiquitin proteasome system as a potential therapeutic target for systemic sclerosis. Transl Res 198:17-28|
|Gaschler, Michael M; Andia, Alexander A; Liu, Hengrui et al. (2018) FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidation. Nat Chem Biol 14:507-515|
|Qu, Yanyan; Olonisakin, Tolani; Bain, William et al. (2018) Thrombospondin-1 protects against pathogen-induced lung injury by limiting extracellular matrix proteolysis. JCI Insight 3:|
Showing the most recent 10 out of 95 publications

domain: literature


Karina is participating in the Gold Global Citizen Award. This is the first of her Global Blogs from South Africa.
By Karina McGinley
There are a plethora of definitions for irregular migration, but as it is a ‘vague blanket term’ there is not one that is broadly accepted. For the purpose of this article the International Organisation for Migration’s (IOM) explanation of an irregular migrant, as someone ‘who owing to unauthorised entry, breach of condition of entry or the expiry of his or her visa, lacks legal status in a transit or host country’, will be employed. This article will explore the entrenched pattern of intra-regional irregular migration from Mozambique, on the eastern coast of southern Africa, to mining areas in South Africa. It endeavours to assess the vulnerability of Mozambican miners, recruited by private companies outside the framework of South African immigration law, and their dependents at home to HIV. This will be done by examining how their working conditions, living arrangements, access to healthcare and remittance channels contribute to the diffusion of HIV/AIDS. This article will use a study, conducted by The National Institute for Health in Mozambique, of 709 Mozambican men who worked in South African mines to draw a conclusion on whether irregular migration is a reason why the HIV and AIDS epidemic is so virulent in South Africa and Mozambique.
The ‘migratory process’ describes the factors that lead to migration and influence where people go. The long-standing pattern of irregular migration from Mozambique to South Africa is attributable to many push factors, such as war. However, this article will focus on economics, which have been recognised as a pull factor for migration since the nineteenth-century. Despite sharing a porous border, there are huge economic disparities between these countries. South Africa, endowed with abundant mineral resources, is the ‘economic powerhouse’ of southern Africa and deemed to possess lucrative employment opportunities. In comparison, Mozambique is one of the Least Developed Countries in the world. Economics coupled with geographic proximity and the presence of existing networks, that decrease the economic, social and psychological costs associated with migration, make the mining areas of South Africa the preferred destination for irregular migrants.
South Africa is a labour-importing country. The migrant labour system began with the demand for cheap labour following the discovery of gold on the Witwatersrand in 1886. Labour migration was driven by powerful private companies that were given a special dispensation to operate outside immigration laws. For example, contract labour migration did not fall within the realm of the Aliens Control Act, which was perceived to be a draconian piece of legislation that sought to regulate all facets of immigration. Consequently many labourers were irregular migrants as they were recruited by companies who did not adhere to South African immigration policy. Mozambicans constituted the largest group of foreign-national workers in the mines, 110,000 Mozambicans worked in South African mines in the early 1970s. However, the Immigration Act, 2002 means that mining companies now have to ‘apply for corporate permits to import an agreed number of migrants’. But, the migrant labour system remains a structural reason for the spread of HIV. As miners recruited for this system spend the majority of the year ‘away from home in an all-male environment of macho-masculinity with easy access to transactional sex’.
Sub-Saharan Africa, where both Mozambique and South Africa are geographically positioned, is the epicentre of the global HIV and AIDS epidemic. The virus, a medical condition restricted to only a few modes of transmission, is one of the most pressing issues afflicting the region. UNAIDS reported that southern Africa bears a disproportionate share of the global HIV and AIDS burden, with 69 per cent of the world’s HIV positive population living there in 2011. The role of migration in transmitting infectious diseases is well-documented and there is consensus in extant literature that the diffusion of HIV and AIDS is ‘inexplicable without reference to human mobility’.
The lack of reliable data makes it difficult to determine the number of Mozambicans residing illegally in South Africa. As the political salience of irregular migrants has grown governments are using alarmist figures and discourse. For example, in 1998 the Minister for Home Affairs, Mongosuthu Buthelzi, commented that South Africa’s socio-economic resources were ‘‘being burdened by the presence of illegal aliens’’. However, from deportation figures published by the Department of Home Affairs it can be determined that their time in South Africa is characterised by impermanency. Mozambicans represent the largest foreign-national group dispelled from South Africa each year. For example, 69,533 irregular Mozambican migrants were removed between January and August 2001. The precariousness of their time in South Africa means that HIV is only one of a broad gamut of dangers they face. Therefore, as it is not fatal immediately they are not motivated to take precautions to prevent transmission.
Employment for irregular migrants in South Africa is spatially concentrated around mining metropolises, well-documented areas of vulnerability to HIV and AIDS. The ‘spaces of vulnerability’ concept outlines that ‘health vulnerability’, for example susceptibility to HIV and AIDS, is not simply a consequence of behaviour but also of environment where irregular migrants reside. For Mozambican migrant men who work in the mining sector death and injury are omnipresent. A job in the mines also entails separation from a regular sexual partner and being surrounded by an active sex industry. The IOM has reported that the dangers and ‘adverse working conditions’ encountered in the mines motivates ‘migrant workers to seek solace and intimacy through multiple sexual encounters’. Thus as border-crossing results in anonymity irregular migrants, released from the behavioural norms of their community of origin, are more likely to have concurrent partnerships. This amplifies their chances of contracting HIV and leads to a diffusion of the epidemic, initially in South Africa and in Mozambique upon their return.
Self-efficacy is an important determinant in health-related behaviour. If one does not feel in control of their life this extends to their health. Irregular migrant miners are powerless against seismic movement and their fate against immigration authorities. In an interview a mine-worker from Lesotho, working in South Africa, commented that he would prefer not to know his HIV status, ‘it is better not to know and live your life’. The same is true for Mozambican mineworkers. The aforementioned study conducted in 2012 found that 74.6 per cent of those that tested positive for HIV did not know their status. This means that they engage in sexual-relations unaware that they have the virus and unconsciously transmit it to others.
There is no single explanation for the spread of HIV and AIDS among irregular migrant labourers and their dependents in Mozambique. However, single-sex hostels provided by mining companies are significant reservoirs of infection. They offer scant leisure amenities, limited privacy and are ‘the ideal environment for any sexually transmitted pathogen’ to find a niche. Alcohol and commercial sex, both conducive to the spread of HIV, are the only diversionary activities within close proximity. They render their inhabitants more susceptible to HIV as ‘peer-pressure’ to ‘adopt a ‘‘macho-masculinity’’ in which manhood is equated with prolific sexual prowess’ is pervasive in the all-male environment. Thus, men living in hostels are coerced into engaging in risky sexual behaviours which exacerbate their chances of contracting HIV.
As part of a more widespread trend there has been a ‘feminisation of migration’ from Mozambique to South Africa in recent years, but the IOM has reported that women are more likely to hold ‘irregular status’. Women migrate to the mines for altruistic reasons. They hope to earn enough to remit money home. However, as mining is a gendered occupation, dominated by men, they find it exceedingly difficult to secure employment. The gender disequilibrium surrounding mines has created a milieu where commercial sex work (CSW) can thrive. Thus in the face of limited employment prospects CSW, that brings short-term financial benefits but long-term health repercussions, becomes a survival mechanism for women. It is clear that the irregular migration of women, to the mining towns in South Africa, contributes to the diffusion of HIV and AIDS, as the employment that many of them engage in to survive strengthens their chances of contracting HIV.
Unprotected sex facilitates the spread of HIV and AIDS. Research has found that migrant miners are unwilling to use condoms when they spend some of their resources on sex. For example, only one in five Mozambican mineworkers used a condom the last time that they had sex, despite 94 per cent stating that they had access to free condoms at work.
Reasons they have articulated for their abhorrence of condoms include the belief that they inhibit virility and that their chances of contracting HIV are less than dying underground. In an interview a CSW stated that because their sexual-relationship decisions are determined by economic circumstances they have no choice but to have sex with men who insist on not using condoms. The South African Constitution (1996) guarantees the right to basic healthcare to all living in the country, regardless of their legal status. However, migrants that cross the border clandestinely are confronted with insurmountable barriers in accessing medical services. They cannot present themselves for treatment as they may be deported. As irregular migrant CSWs cannot readily access adequate healthcare they are unable to find out their HIV status. Therefore, they continue their livelihood strategy, which entails unprotected sex, without knowledge of their HIV status. Thus, they may transmit HIV to men that procure their services. This demonstrates that irregular migrantion has a significant impact on the incidence of HIV and AIDS.
Daan Brummer (IOM) highlights that irregular migrants do not simply act as vectors carrying and spreading HIV. He articulates that owing to their uncertain status they are more vulnerable to infection. The findings of the 2012 study that has been used throughout this paper corroborate his sentiments. As 14.5 per cent of the Mozambican mineworkers who tested positive for HIV during the research, reported that they tested negative a year before the survey. This increase is attributable to high-risk behaviour that they admitted to engaging in as a mobile person, faced with the danger of mutilating accidents in work each day and living in crowded hostels. This study also confirms the thesis that mobility, outside the framework of the law, leads to the diffusion of HIV and AIDS.
There is a cyclical relationship between poverty, irregular migration and HIV.Poverty drives irregular migration which acts as a catalyst for the spread of communicable diseases. HIV, one such transmittable disease, perpetuates poverty, which once again induces migration.
Remittances could also be included in this relationship as they play an instrumental role in poverty alleviation. However, owing to their legal standing irregular migrants cannot access formal remittance channels, such as banks. They rely on informal channels, such as cross-border taxis, which carry a greater risk. Therefore, despite being an integral source of income for many households in Mozambique, they are not reliable. This means that dependents in Mozambique have a similar precarious existence to irregular migrants and share the same vulnerability to HIV and AIDS.
Like Brummer’s aforementioned thesis that dispelled the unidirectional flow of transmission from migrant to receiving country, the ‘accepted wisdom’ that migrants go to the mines, contract the virus and infect their partners when they return home is simplistic and naïve. As part of a study to examine the vulnerability of migrant miners partners to HIV eighty Mozambican women were interviewed. From the research, it was found that in year preceding the interview 14 per cent of the women ‘had sex in exchange for goods or money’. By having multiple sexual encounters with men for financial support and engaging in sex-work to satisfy their basic needs these women increase their chances of contracting HIV. Therefore, it is clear that the prevalence of HIV and AIDS in Mozambique is a manifestation of the deteriorating economic conditions that are a consequence of the unreliable remittance channels available to irregular migrants.
Mining has been a pillar of the South African economy for decades. However, the industry is in a parlous state and beginning to stagnate. This was seen through the recent strike, when miners paralysed the production of platinum from January 2014 until June 2014 by downing their tools ‘to demand a living wage’. This strike had impacts for mine-workers dependents in Mozambique, who did not receive remittances during this period. Mines in South Africa are old and deep. This increases the costs involved. Consequently many mining companies, including Anglo-American Platinum, have articulated their intentions to close down unprofitable operations. It has shortlisted potential buyers for its Union mine in Rustenberg and aims to sell it for $300 million in 2015. Declining employment in mines has led to a proliferation in illegal mining activities, in both operational and abandoned shafts.
The reported number of illegal miners called zama-zama, a Zulu word meaning he who seizes the opportunity’, has grown exponentially in recent years, as South Africa’s global positon as a gold producer has fallen. An article in The Guardian elucidated that zama-zamas are typically irregular migrants from poorer neighbouring countries, such as Mozambique. They are lured by the possibility of earning a significant amount of money. However, as they do not have a regular, fixed income, the sum they remit fluctuates. For example, in an interview Joseph Sithole, an undocumented Mozambican migrant working as a zama-zama, highlighted that he earns less than $5 per day. However, he stated that it is worth the risk, as ‘hitting a rich seam’ will enable him to remit more money home to Mozambique. Therefore, if amount repatriated is insufficient to satisfy subsistence needs or if the remitter dies or is maimed in the mine other family members may be forced to migrate or engage in sex-work, thus increasing the incidence of HIV/AIDS in Mozambique and South Africa.
Illegal mining is a result of economic necessity. This was highlighted by the Daily Sun, a sensationalist newspaper, which has the largest readership in South Africa. On 19th June 2014 the front page contained the headline ‘Dying to live’, this feature story on zama-zamas, stated that ‘their families would starve if they didn’t battle the dangers underground’.
Sipho Mahabane, a zama-zama, commented that illegal mining is not ‘‘a choice but a must for survival’’. The reality of life in the subterranean tunnels and surrounding environment creates conditions that induce the spread of HIV. Inflated prices and CSW prevail. Legal workers ‘‘have made a killing’’ from zama-zamas. They charge exorbitant amounts for basic foodstuffs, such as 100 Rand for a loaf of bread which normally costs 8 Rand. Similar to around operational mines, CSW has prospered in the milieu surrounding abandoned mines where it is known that zama-zama work. Therefore, if illegal miners are spending money underground or on sex they do not have surplus money to remit home and increase their chances of contracting HIV. This perpetuates the cyclical relationship between poverty, irregular migration and HIV.
The geography of HIV and AIDS in Mozambique ascertains that the epidemiology of the virus is inextricably linked to the process of irregular migration. The epidemic has spread rapidly in recent years. In 2004 the HIV prevalence rate among Mozambique’s adult population (fifteen to forty-nine years) was 16.1 per cent, and fastest growing in provinces linked by transportation corridors to South Africa. HIV now accounts for 27 per cent of all deaths, the second largest after malaria. However, the Mozambique National Institute of Statistics found that HIV and AIDS was the leading cause of adult deaths (aged fifteen plus), accounting for 40 per cent. The figure varied across regions. It ranged from 32 per cent of deaths in Nampula, in the north, a considerable distance from transportation routes to fifty per cent of deaths in Gaza, along the South African border. This disparity correlates with irregular migration patterns and substantiates the thesis of this paper that mobility has a significant impact on the diffusion of HIV and AIDS in Mozambique. Researchers from the University of Witwatersrand concluded that the prevalence of HIV and AIDS in southern Mozambique is the ‘hallmark of social disruption’ caused by irregular and oscillating migration.
In conclusion, there is a clear link between the prevalence of HIV in Mozambique and irregular migration to South African mines. This was elucidated in this article by illustrating how the geography of HIV/AIDS in Mozambique correlates with patterns of irregular migration and how dangerous conditions in the mines, where irregular migrant Mozambican men work, increase the incidence of high-risk sexual behaviour that facilitates transmission. The connection between being dependent on an irregular migrant and increased susceptibility to HIV was explored by assessing the impact of the termination of remittances. Mobility has been an ubiquitous characteristic of our history. The complex mix of social, economic, political and environmental factors that compel people to migrate irregularly from Mozambique to South Africa will not be eradicated overnight or stemmed by stringent immigration policy. Therefore a long-term, cooperative and multi-faceted response that tackles the underlying causes of irregular migration, which is intimately connected to HIV and AIDS, must be found.


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Are you, like 90 percent of Americans, sleep deprived? Are you experiencing lack of sleep, sleep issues, no more dreams in sleep, disturbed sleep (without being a parent of little ones), or any other sleep problem?
Sleep is the number one problem in America today. The Huffington Post describes this as leading a life unsustainable, otherwise known as, Exhaustion.
People have grown to believe the lie, or myth, that they can handle less sleep than those before them, and that 4-5 hours of sleep is enough… yet, those same people, statistically, have sleep issues that have gone deep into their systems; this is a lack of one of the most fundamental aspects in life.
Sleep has had many changes in history. Weekends, just a few decades ago, used to be for vegging out, relaxing, resting; stores were shut down, and people socialized, or stayed home with the family. One can look back into history and see these changes fairly easily now with the online connections, or asking grandparents (oh, that would cause person to person communication, which is nearly unheard of now).
Correlation between sleep and weight loss, sleep and choices, sleep and food, sleep and… fill in the blank. Sleep has an impact on just about everything. One can be completely healthy, eat well, drink well, and still have issues just from lack of sleep or true rest (or the build up of such). Many good folks confuse sleepy with hungry, are dependent upon stimulants, confuse rest with inebriation, and try to swallow sleep.
Rubin Naiman, an expert doctor of sleep, has some good references to sleep and some good advice. He says we consume and absorb food, information, oxygen (air), light and energy. Much of our information, food, air, light and energy are over consumed or of poor quality. This over consumption literally heats us up (chronic inflammation). In general, the population has forgotten what rest is; recreation is NOT rest. We are literally RESTLESS. Naiman tells of a story of a young child who was found on the bookshelf above the bed; when asked why she was there, she replied that she was afraid of falling off the bed so she climbed “up”. This tells something of the human mindset. We try to get higher and higher, up our energy, and we are reluctant to go down and to let go. We land into sleep much like a jet hitting turbulence; we go back up into the thoughts and energy. Hyper arousal is defined as insomnia, increased metabolic rates, elevated heart rates, elevated core body temperature, increased high frequency, elevated nighttime cortisol, nocturnal sympathetic activation, and over-active HPA.
Most sleep loss is in the dream state (REM). REM is important for memory retention, cleansing of information, and absorption of information. It is the reason memory loss is on an increase and other similar disorders; not dreaming is directly related to memory deficiency. Dreams involve emotional healing. The brain is a second gut, and must go through the same things as the gut: digest, assimilate, absorb, and cleanse. When dreaming is suppressed, the pattern matches mood patterns.
One last thought:
Light is important. Dark is important. We have been trained to think dark is bad. I think differently on this. Dark is good. Dark is needed. Dark is just dark. When the sun sets, the lights dim, and our eyes need rest from the light. We need to sit in dim light, and dim our computer screens (or not have them on at all at night), and let dark be a thing for us and our bodies to embrace. Horizontal is balancing, unlike any other position. If we are in harmony with nature more, we will be at the right place in the right place, at the right time.
Now, rest, sleep well my friends.
For more information on how to change your sleep, and come to understand what you can do for your sleep, contact me and set up an appointment. Together we can make a plan for you. Together we can change our homes, our families, our communities, one sleep at at time 🙂 I can do consultations by phone or in person.

domain: health


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Red Fleet State Park is a state park of Utah, United States, featuring a 750-acre (300 ha) reservoir and a fossil trackway of dinosaur footprints. The park is located 10 miles (16 km) north of Vernal.
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I’ve been experimenting with kneading approaches and after a couple of loaves made with this way of kneading, I can safely say, this makes better bread than before, and I am happy now. This only applies to firm or moderately loose doughs, that benefit from strengthening. For rye doughs (rye > 90%) one just has to make sure the hydration is high enough to get a good aeration.
1. Knead in short intervals, briefly, for about 30 minutes (à la Dan Lepard).
2. Knead the dough by hand for about 7-10 minutes vigorously, stretching it quite forcefully and slapping it on the counter.
Conclusion: I just sucked at kneading, so more attention to it helped my bread.

domain: food


Find the most recent information on EU Funding activities in the field of Information and Communication Technologies (ICT) by visiting our ICT in FP7 website, which covers ICT in the 7th Framework Programme (FP7) 2007 - 2013.
To strengthen security and enhance dependability of the information and communication systems and infrastructures and to ensure trust and confidence in the use of IST by addressing new security and dependability challenges. These are resulting from higher complexity, ubiquity of computing and communications, mobility, and increased dynamicity of content. Integrated and comprehensive approaches involving all relevant stakeholders of the value chain should address security and dependability at different levels and from different perspectives.
The Strategic Objective 'Towards a global dependability and security framework' is included within Call 1 of the IST priority.
|Publication date||Closure date||Pre-allocate budget1 (M€)||Instruments||Status|
|17 December 2002||24 April 2003||55||All2||Closed|
Commission's contact persons for the IST calls 2003-2004
- Andrea Servida (Contact Form)
1 The amount corresponds to the 80% of the budget which is pre-allocated.
2 'All instruments' correspond to IPs, NoEs, STREPs, CAs, and SSAs.


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DeSean Jackson’s spokesman has released a statement to the Inquirer saying that the pro bowl WR made “an honest mistake” when he overslept and missed a special teams meeting on Saturday. The spokesman says that DeSean understands the suspension and still wants to be a part of the team.
“He wants to be an Eagle, he’s happy being an Eagle, he loves what he’s doing in the community, but he realizes there are consequences for his actions and he’s not above the team,” said Jackson spokesman Bobby McRae. “When he gets back he’s going to be motivated and he’s going to work hard to contribute to what he needs to do.”
DeSean Jackson is in the final year of his rookie contract and has been looking for a new deal this season. This past Monday was the deadline to put bonus money on this year’s cap, so often that means that extensions get done before that.


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Bali Natural Stone Supplier – Exotic Bali Natural Stone for Swimming Pool Project
Beside Kuta, Tanjung Benoa has become the favorite tourism object due to its many exciting attractions. Let’s say Banana Boat, turtle conservation, or even scuba diving. Since there is also the significant escalation of tourists at TanjungBenoa, it gives a big impact on the development of many inns and villas. One of the best hotels you can find in TanjungBenoa is the Holiday Inn Resort. The resort gives you a tropical ambiance, and it is completed with the beautiful decoration, such as Bali Natural Stone at Holiday Inn Resort Tanjung Benoa Bali. Such a stress reliever when you are in Bali.
There are many whimsical stones in the world, but Bali Stone is one of the most preferred that you must also consider. This Bali Natural Stone at Holiday Inn Resort Tanjung Benoa Bali gives natural looks for the lavish hotel and make the tourists closer to nature. It is also effortlessly beautiful and doesn’t need too much decoration to make it stand out. This natural stone is just like the natural stone you can find in the wild nature. But it seems more tidy, clean, and also elegant. It also gives you a visual relaxation that you will need after exploring Bali all day long.
Natural Stone Tiles In Indonesia – Where to Buy Bali Natural Stone?
The Bali Natural Stone at Holiday Inn Resort Tanjung Benoa Bali is usually used to greet all the guests in the lobby, but you can also use it as the base on the pool. It won’t absorb heat so that will be good to chill up on the bright day. The natural stone made up in Bali is also good for the flooring idea. Its rough surface won’t let you slip so that it is safe for the bath flooring or the flooring near the swimming pool and sauna room. Besides using the flooring or wall coverage, other good options are to use the Bali Natural Stone as the bath-tub or wasteful. The thing you can easily find at Bali.
Either you have an inn with the traditional theme, contemporary, or even the ultra-modern ones, you can always use the natural stone just like Bali Natural Stone at Holiday Inn Resort Tanjung Benoa Bali. The stone suits any room theme and can be used to form any kind of pieces of furniture and decoration. You can have a very modern room with a table made of natural stone or a bathroom covered with transparent glass but the washstand from Bali natural stone. The natural stone of Bali comes with many kinds, from the big and rough surface to the natural pebble stones. If you intend to present the gorgeous looks with the Bali Stone, feel free to contact Stone Depot to get the best deal of Bali Natural Stone in various kinds.


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Mamma Mia! Movie Reviews
User reviews on Mamma Mia!
This movie was spectacular, i've seen it 3 times and im still not tired of seeing it, i usually like all musicals but ths one is just magnificent!!!! !!!!!!!
Momma Mia â€“ The title sez it all! For the record: I am not now, nor have I ever been a fan of movie musicals. As far as I am concerned musicals belong on the stage. I appreciate, I think, the genre, but I can do without â€˜Singing in the Rainâ€™, â€˜Kismetâ€™, â€˜West Side Storyâ€™, â€˜Oklahomaâ€™, etc. I just canâ€™t get my imagination to accept that people start singing and dancing, in perfect accord, out oâ€™ the blue and nobody has dropped acid or extasyâ€¦â€˜Mom ma Miaâ€™!!! However, I limit my hypocrisy to â€˜Jailhouse Rockâ€™, â€˜Viva Las Vegasâ€™ and â€˜Paint Your Wagonâ€™. Truth be told, I do have a wild fantasy to see and hear John Wayne sing â€˜The Lonely Goat Herdâ€™ (from â€˜Sound of Musicâ€™) w/a dance choreographed by Bob Fosse. Sometimes the fantasy is best left a fantasy.
The Line Is Etched in Stone.
I remember ABBAâ€™s songs on the radio back in the 70â€™s and into the 80â€™s, but I never bought one of their albums. They were/are too â€˜bubble gumâ€™ for my tastes along with Bobby Sherman, David Cassidy and the Osmonds earlier in the 70â€™s. I never bought any of their albums either. â€˜Momma Miaâ€™ is an all out estrogen flick, if ever there was one! I will bet that within the next 10 years the Castro Theater, in the heart of San Franciscoâ€™s â€˜gayâ€™ district, will show this movie (maybe as a double bill with â€˜Moulin Rougeâ€™) as a â€˜sing-alongâ€ ™ presentation. They already do this with â€˜The Sound of Musicâ€™, â€˜Greaseâ€™ and Disneyâ€™s â€˜The Little Mermaidâ€™. Not that there is anything wrong or derogatory about men of all ages dressing up as their favorite female character, make up and all, for a night at the theater to sing the movie. Iâ€™m all over â€˜Live & Let Liveâ€™ like white on rice, but itâ€™s just a wee bit TOO much estrogen for me.
On the other hand, it is kind of refreshing that anyone make an out & out musical in this foul year of the Bush Empire where there is no villain, no bad guy or antagonist of any kind! There are no weapons No bloodshed, no decapitationsâ€ ¦not even as much as a groin injuryâ€¦period ! And absolutely no CGI. Amazingâ€¦total ly escapist fare! All my cards on the table, for the first time in my life, I was so turned on at the sight of Meryl Streep anything that happened on the screen was fine with me. I would not say I am a fan of hers, she is excellent in everything Iâ€™ve seen her do, but I donâ€™t mark my calendar and I damn sure donâ€™t camp out to see herâ€™s or anyoneâ€™s movies. This time out she plays a reformed globe trotting â€˜party girl/s***â€™ whose 20 year old daughter is getting married. The daughter wants her father to give her away, but after stealing her motherâ€™s journal she discovers there are three different possibilities. So, she invites them all, without momâ€™s knowledge, figuring sheâ€™ll be able to tell who her father is at the sight of him. When they all show up on the same boat she canâ€™t. Then, itâ€™s one ABBA song after another. However it wasnâ€™t an endurance test like â€˜Sex In The Cityâ€™ was to me. (when I begin to daydream of a â€˜Bloody Samâ€™ Peckinpah version the movie Iâ€™m watching, itâ€™s in trouble. â€˜Sex in the Cityâ€™ also garnered an additional imaginary Tarrentino, version, a John Woo version and a Monte Hellman in the twisted recesses of my mind.) In good conscious, I could recommend â€˜Momma Miaâ€™ to anyone who loves movie musicals and ABBA.
This movie was about as good as The Love Guru. It strait up sucked. There are nly three surc**stances in which you will like this movie. 1. Your a hardcore ABBA fan
2. Your a middle age women
3. Your a gay guy This movie is in no shape form or fashion going to be the next hairspray. Many flaws in this movie include he fact that it is perverted and Pierce Brosnan can not sing worth living. Please , if you have a desire to see this movie buy tickets to another movie and sneak in.
I loved it. I love Meryl Streep in almost everything she plays in. It was like being at a great party. When the movie was over, not a soul moved. Everyone sat spellbound waiting for the credits and then clapped when it was over.
Just to let you know, it is totally possible for a 59-year-old to be the mother of a 20-year-old, and for parents of a pregnant, unwed 39-year-old to be appalled! These demographics happen all the time!
This was a fantastic movie and the three women "friends" were perfect in their roles. They totally go with the ABBA theme, nostalgia and everything else.
I liked the movie, but I did have some complaints. After seeing the off-Broadway play last year, i was astounded at the casting. A 59 year old Meryl Streep did AWESOME but she was still clearly too old to play the mom of the 20 year old bride. At one point she says her mom wouldn't let her come home because she got pregnant...at 40? She really acted younger, but they up-aged the cast to fit her age. Baranski..funny but not the sex symbol either. Would have liked Kirsten Chenoweth or Michelle Pfiffer in lead. But the music is great and it's a fun movie nevertheless.
I went to see it last Friday... I loved it!!! Streep stole the show. Beyond comic, funny, light-hearted, heart-touching emotions. The choreography is impressive, great music, and the SCENE totally transports you. Its too good!
This movie was absolutley amazing!!!! I went out last night and saw it.....and now I am looking at the times for today...it was that good!
I have never liked a movie so much that I have seen it twice in a 24 hour time period.
Go see it!
The cast is phenomenal, they all sing their own parts, and Meryl Streep gave an oustnading performance!
O h, and if you go see it, you have to stay for the end credits...trust me
It sure is refreshing to go see a fun, funny, and dare I say - HAPPY movie! I thought Mama Mia! was great. I liked everything about it - especially all of the smiles and happy people. The singing and dancing was wonderful - I can't think of one moment of that film when I wasn't smiling. Great job to all of the people involved and your ability to bring to the world a positive and upbeat movie.
Horrible. A fabricated mess with forced silliness and over-the-top cartoonish performances. To say the performances were OVERACTED is like saying getting hit by a Tsunami will make you moist. Yes, it's a musical so you expect exaggeration. I love musicals, but, this one doesn't work at any level. Zero chemistry between performers. The plot and theme is ridiculous. I'll say it again, whatever you see on screen is forced. There is no natural flow where you can just sit back and enjoy. It just comes across as artificial.


Ratio Home charger with Type 2 Socket - up to 3 phase 32
Which combinations are possible?
Although the Ratio charge points are available with many different options, not all options are possible. Below is a brief overview that you should pay attention to when you assemble your charge point:
- "Load Balancing" is only possible in combination with a "built-in kWh meter" and only for versions with 32A (both 1 and 3 phases)
- All other combinations are possible
For which vehicles is this charging point suitable?
This charger is suitable for all electric vehicles that have a Type 1 or Type 2 connection to the vehicle. You can connect your own cable yourself so that you can charge any vehicle with a public charging cable. These are, for example, electric vehicles or plug-in hybrids, such as the BMW i3, Mercedes-Benz A-Class E-Cell, Porsche Panamera S E-Hybrid, Renault Zoe, Smart Fortwo Electric Drive, Tesla Model S, Volkswagen E-Golf, Volvo V60 plug-in hybrid, Tesla Model 3, Hyundai Kona, Mini Countryman, BMW 530e, Kia Niro PHEV, Volt, C-zero, Berlingo Multispace, Fiat 500e, Ford Fusion Energi, C-Max Energi
Focus Electric Honda Jazz, Accord Plug-in, Clarity Electric, Clarity Plug-in Hybrid, Fit EV, Hyundai i10, Kia Soul EV, Mitsubishi Outlander, MiEV, Nissan E-NV200, Leaf and many others.
These chargers are especially useful if you have to load many different types of cars. If you always have to load the same type of car, we recommend that you purchase a charging point with a fixed cable. This prevents you from always having to remove the charging cable from the car.
Which charging speeds does this charging point support?
Your actual loading speed of your car depends on the charger of your vehicle. Below you will find an overview of the different charging speeds that this cable supports. Click here for more information:
32A with 1 phase = max. 7.4kW
32A with 3 phase = max. 22kW
Smart charging is an extra option for your charging station which is available at most charging points that we offer via Cable Soolutions. With Smart Charging you can charge your car smartly and minimize the one-off and annual costs for electricity connection. There are two functions within Smart Charging. The charge point ratio are equipped with both functions (optional):
- Load Balancing: ensures that the car charger never exceeds the peak power of your connection. This prevents extra costs from your network operator. The charging points hereby have an additional communication connection with the existing meter or with additional sensors to be placed. This differs per manufacturer. For the ratio stations, load balancing is only available for variant with 32A maximum. Not available for 16A versions.
- Panel Sharing: if you connect multiple charging points to an electrical connection, Panel Sharing ensures that the available power of the entire connection is smartly distributed if multiple vehicles are charging. If one of the vehicles is fully loaded, the remaining load capacity then goes to the vehicles that still have to be loaded.
Smart Charging ensures that your charging station always makes smart use of the available load capacity. By smartly charging your electric car with a Smart Charging charging point you can save up to hundreds of euros per year.
Use extreme caution when installing the charging station. It is recommended that the construction is carried out only with prior knowledge or by a trained professional.
The charging points of ratio are available with and without Load Balancing. The load balancing versions come in a master and a slave version. If you only install 1 load point with Load Balancing, you need a master. The versions offered here with load balancing are always Master's and are supplied with an additional measuring core which must be placed at the main connection in the meter box.
If you also want to place an additional charging point on the same mains connection, then a Slave in combination with a Master is sufficient. A maximum of 3 Slaves can be connected to 1 Master. If you want an extra Slave you can order it separately from us. These cannot be ordered directly via the website.
In order for this charging station to work with 32A and 3 phases, you need at least a 3 phase 400V connection of at least 3x35A. If you have less than 35A you can also set the charging point to a lower maximum charging current or connect to 1 phase.
Do you have any questions about Smart Charging?
Cable Soolutions is happy to advise you on your energy management issue. Please contact us if you want an explanation about what a smart EV charger can mean for you
- Requires Professional Installation:Yes
- Length (in meters):Bring your own cable
- IP Rating:IP54
- Max Charging Speed in km/h:60 km/hour
- Max Charging Speed in kW:7,4 kW
- Plug type Car side:All car plugs supported. Minimal type 2 on stationside is required
- Plug type Charge station side:Type 2 Socket
- Cable Attached or Socket:Socket
- kWh meter Build in:Optional at extra cost
- MID certified meter:Optional at extra cost
- RCD type build in:No
- 6mA DC Current Detection:Yes
- Network Technologies Supported:Not Applicable
- Mobile app Support:No
- Remote station management:Not Applicable
- Home Automation Support:No
- Number of vehicles that can be charged:1
- RFID reader:No
- Load Balancing:Optional providing Load Balancing and Panel Sharing up to 4 station per Master
- Scheduled Charging:
- Plug & Charge Enabled:No
- Smart Tesla charge port opening :Optional


text:
The Slush Sneaker is so stylish and comfy that you'll wear them “weather” or not it's snowing. We’ve reinvented the conventional winter boot with playful prints, bright colors, and athletic detailing. The Slush Sneaker’s cozy shearling lining creates the ultimate snowy-day comfort. Our Bounce™ footbed adds extra energy return with every step and the easyclean rubber ensures totally dry feet. Plus, we've added pull tabs and stretchy sides to these slush booties, so you can easily kick 'em off as soon as you get inside.
- Synthetic Upper
- Soft faux shearling lining for warmth and comfort against your foot Lining
- TPU Outsole
Weather Sneaker available in sizes M 6-12 (whole sizes only)


text:
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Copyright© 2022 Apkbright


Posts Tagged “Sarah Palin”
Posted by ThirstyJon in Freedom Ideas, News, Politics, and World Events, tags: and World Events, Big Government, CNN, CNN.com, Michelle Obama, News, Obesity, Politics, Roland Martin, Sarah Palin, The Government is not the answer, U.S., World Events
I just read an article by Roland Martin at CNN.com. He is ripping on Sarah Palin because she was pointing out the error of thinking that the federal government is the answer to obesity in America.
Roland Martin does not get it.
Here is a bit from the article:
“It’s clear that we can’t go 24 hours without Sarah Palin saying something so stupid that it defies logic, but leave it to the Kim Kardashian of politics to find something wrong with first lady Michelle Obama’s effort to curb obesity in America’s kids.
“In a radio interview on Wednesday with conservative talker Laura Ingraham, Palin took dead aim at the first lady’s ‘Let’s Move’ initiative, which is all about getting children active and involved in exercise and healthy eating.
In the wacky world of Wasilla’s finest, Palin tries to cast the effort to fight obesity as part of Michelle Obama’s ‘different worldview.'” [Read More]
Here is my response that I posted at CNN.com:
Roland Martin doesn’t get it.
Does he actually believe that the federal government can stop obesity?
This is the same false reasoning that statist proponents always use – they actually believe that by showing a problem exists that it follows logically that the federal government needs to “fix” the problem.
It is now and has always been a myth that a huge centralized government is the answer to problems. Individual and local initiative is the answer.
The federal government cannot succeed in solving this kind of problem.
The risk of way to much intrusion in our lives is to great if the federal government tries.
When will statists like Roland Martin wake up?
When will Americans wake up and stop taking the kind of nonsense in this article seriously?
No Comments »
Posted by ThirstyJon in Kingdom Ideas - Worldview, News, Politics, and World Events, tags: Barack Obama, Big Government, Commentary, Death Panels, Euthenasia, Health Care, Health Care Reform, Pro-Life, Sarah Palin, Threats to Liberty
I’m sure you’ve been listening to the debate about “Death Panels.” Our President has called them a Myth.
I believe Sarah Palin coined the phrase here: http://www.facebook.com/note.php?note_id=113851103434
When Barack Obama tries to stop this “deception” he does so by saying it is an outright lie, there is no “death panel” in any current legislation.
I think he is missing the point. Palin is addressing the mentality behind the bills and the implications of the bills as well. She clearly shows this in a subsequent note here: http://www.facebook.com/note.php?note_id=116471698434
Here is a quote from that article:
“Of course, it’s not just this one provision that presents a problem. My original comments concerned statements made by Dr. Ezekiel Emanuel, a health policy advisor to President Obama and the brother of the President’s chief of staff. Dr. Emanuel has written that some medical services should not be guaranteed to those ‘who are irreversibly prevented from being or becoming participating citizens….An obvious example is not guaranteeing health services to patients with dementia.’ Dr. Emanuel has also advocated basing medical decisions on a system which ‘produces a priority curve on which individuals aged between roughly 15 and 40 years get the most chance, whereas the youngest and oldest people get chances that are attenuated.'” [Read More]
I just read an article that seems to show these implications coming true in the U.K. I don’t mean to attack the U.K. health system. I have never lived there. Perhaps some of my friends in the U.K. can explain. The point is not to attack a nation, but to try and really see if we can observe the “death panel” type consequences really coming true in a state health care system, whether or not that is the intent of such a system.
You can read that article at JewishWorldReview.com:
“Remember the whole controversy over ‘death panels’—the idea, as President Obama dismissively put it, that greater government control over medicine would cause bureaucrats to ‘pull the plug on grandma’?
Well, for weeks now Britain’s newspapers have been filled with articles about the National Health Service pulling the plug on grandma.” [Read More]
The story has a number of links to articles from U.K. sources about various stories where the “death panel” kind of thing is allegedly taking place.
The United States is in a Worldview War primarily between the ideas of Secular Humanism and the ideas of Christianity. (Sometimes the “Christian” ideas are even pushed by people who are not necessarily “Christian.” They just embrace some of the values.) The rest of the world is in this war as well.
I don’t think we’re at a place where a law could openly say “let those who aren’t productive die;” but it is a clear implication of contemporary worldview to let this happen. Our culture actually considers it a legitimate debate whether or not the wholesale slaughter of the unborn going on through abortion should be illegal. This is not a culture that can be trusted to force a health care plan upon us. If our culture tolerates the murder of innocent unborn children, what will end up being tolerated in the name of saving health care costs? I would suggest we avoid any expansion of government, especially in the current climate.
Just some thoughts.
No Comments »
Posted by ThirstyJon in News, Politics, and World Events, tags: Election 2008, Elections, John McCain, News Commentary, Politics, Pro-Life, Republicans, Sarah Palin
NARAL opposes McCain/Palin because they are too Pro-Life. Sounds like a good reason to vote for them to me! 🙂
Read about it at the HuffingtonPost:
“Today, NARAL Pro-Choice America launched the first in its series of web videos that shows America just how extreme and radical the McCain-Palin ticket is when it comes to abortion, Roe v. Wade, and a woman’s right to choose. And best of all, we have them saying what they believe in their own words — no spin, no re-interpretation of what they said — just the real McCain and Palin.” [Read More]
No Comments »


During my adventures as a Speedhunter I’ve had the chance to point my camera at some amazing machinery. Yet whether it was a high tech race car or a priceless classic, I’ve never shot anything quite like the rig you see here.
A while back I had the chance to check out the insane Spectre Peformance Double Dually and thought you guys might enjoy a quick spotlight on it.
Created by the same minds that brought us the carbon fiber Camaro and 2JZ Ford Maverick, the Double Dually began life as a standard 2004 Chevy Silverado dually. The truck was purchased to be the push vehicle for Spectre’s land speed racers at Bonneville – first their Ferrari F40 and later their Caddy-powered streamliner.
When it comes to push-starting cars at Bonneville, initial traction is crucial. I’d say traction isn’t a problem for the eight driven wheels on the Double Dually’s custom-built rear subframe.
Originally powered by a supercharged GM 8.1 V8, the Dually is now equipped with a 500 cubic inch Cadillac big block with a pair of Garrett turbochargers. Built by the experts at the Cad Company, the motor makes 1,425 horsepower and 1,671 foot pounds of torque. Once the monster Caddy motor was installed, the front end was swapped over to one from an Escalade to keep the theme going.
You probably won’t be seeing many more “Escalades” on this site in the future, but I’d say this one more than qualifies to be a part of the Speedhunters sphere.


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Responsiveness to low-dose warfarin associated with genetic variants of VKORC1, CYP2C9, CYP2C19, and CYP4F2 in an Indonesian population
- 542 Downloads
The aim of this study was to assess the pharmacokinetics and pharmacodynamics of warfarin associated with genetic polymorphisms in VKORC1, CYP2C9, CYP2C19, and CYP4F2 in Indonesian patients treated with low-dose warfarin.
Genotyping of VKORC1, CYP2C9, CYP2C19, and CYP4F2 was carried out in 103 patients treated with a daily dose of 1–2 mg warfarin, 89 of whom were treated with a fixed daily dose of warfarin (1 mg). The plasma concentrations of S- and R-warfarin and S- and R-7-hydroxywarfarin were used as pharmacokinetic indices, while prothrombin time expressed as the international normalized ratio (PT-INR) was used as a pharmacodynamic index.
In patients treated with a fixed daily dose of warfarin (1 mg), a higher PT-INR was associated with VKORC1-1639 AA [median 1.35; interquartile range (IQR) 1.21–1.50] than with the GA (1.18; IQR 1.12–1.32; p < 0.01) and GG (1.02; IQR = 1.02–1.06; p < 0.01) polymorphisms, and with CYP2C9*1/*3 (1.63; IQR 1.45–1.85) compared to *1/*1 (1.23; IQR 1.13–1.43; p < 0.05). The S-warfarin concentration was significantly higher in patients with CYP2C9*1/*3 than in those with *1/*1 (p < 0.05). With low-dose warfarin administration, there was no significant difference in the concentrations of warfarin metabolites among any of the genotype variants. The genotype variations of CYP2C19 and CYP4F2 were not significantly associated with the PT-INR.
For low-dose warfarin treatment, the VKORC1-1639 G > A and CYP2C9 genotype variations affected the pharmacokinetics and pharmacodynamics of warfarin, while we could not find significant effects of CYP4F2 or CYP2C19 genotype variations on warfarin (metabolite) concentrations or PT-INR.
KeywordsWarfarin Pharmacogenetics VKORC1 CYP2C9 CYP4F2
The authors thank all physicians and nursing staffs of the cardiovascular services units in Al-Islam Hospital, Salamun Hospital, and Hasan Sadikin Hospital, Bandung, Indonesia, for their participation in this study. We thank Norisca Aliza Putriana and Sari Handayani for their assistance in collecting patient data and providing technical support. We also thank Aiko Matsumoto for her secretarial assistance.
Conflict of interests
- 19.Gao L, He L, Luo J, Xu B, Yang J, Zhang YX et al (2011) Extremely low warfarin dose in patients with genotypes of CYP2C9*3/*3 and VKORC1-1639A/A. Chin Med J (Engl) 124(17):2767–2770Google Scholar
- 21.Aomori T, Yamamoto K, Oguchi-Katayama A, Kawai Y, Ishidao T, Mitani Y et al (2009) Rapid single-nucleotide polymorphism detection of cytochrome P450 (CYP2C9) and vitamin K epoxide reductase (VKORC1) genes for the warfarin dose adjustment by the SMart-amplification process version 2. Clin Chem 55(4):804–812PubMedCrossRefGoogle Scholar
- 22.Furuta T, Shirai N, Takashima M, Xiao F, Hanai H, Sugimura H et al (2001) Effect of genotypic differences in CYP2C19 on cure rates for Helicobacter pylori infection by triple therapy with a proton pump inhibitor, amoxicillin, and clarithromycin. Clin Pharmacol Ther 69(3):158–168PubMedCrossRefGoogle Scholar
- 29.Kwon A, Jo SH, Im HJ, Jo YA, Park JY, Kang HJ, et al. (2011) Pharmacogenetic distribution of warfarin and its clinical significance in Korean patients during initial anticoagulation therapy. J Thromb Thrombolysis 32(4):467–473Google Scholar
- 35.Singh O, Sandanaraj E, Subramanian K, Lee LH, Chowbay B (2011) The influence of CYP4F2 rs2108622 (V433M) on warfarin dose requirement in Asian patients. Drug Metab Pharmacokinet 26(2):130–136Google Scholar
- 36.Nakamura K, Obayashi K, Araki T, Aomori T, Fujita Y, Okada Y, et al. (2012) CYP4F2 gene polymorphism as a contributor to warfarin maintenance dose in Japanese subjects. J Clin Pharm Ther 37(4):481–485Google Scholar
- 39.Gan GG, Phipps ME, Lee MM, Lu LS, Subramaniam RY, Bee PC, et al. (2011) Contribution of VKORC1 and CYP2C9 polymorphisms in the interethnic variability of warfarin dose in Malaysian populations. Ann Hematol 90(6):635–641Google Scholar


text:
Today we’d like to introduce you to Renae Goodhew.
Renae, can you briefly walk us through your story – how you started and how you got to where you are today.
I grew up in South Bend, Indiana and attended Ball State University where I received a degree in Theater Production and Design with a minor in Art. I always knew that I wanted to be a makeup artist and move out to Los Angeles, but it wasn’t until I finished college that I finally made that leap.
Once settled, I enrolled in Cinema Makeup School where I was taught every fundamental aspect of beauty and special effects application over an intensive 6-month curriculum. It was at the Cinema that I met Lee Joyner, an amazing sculptor and SFX artist, who over the years has become a great mentor and friend. Still to this day I go to him for guidance.
After completion of the program at Cinema, I began outlining goals and setting plans in place to achieve them. As anyone who works in this industry knows, this was not easy. But before I knew it, I started landing jobs with various SFX Labs and then worked as a freelance makeup artist doing lower budget shoots (i.e., independent horror films, short films, photo shoots, etc.) to gain further name recognition. Eventually, my rapport in the industry grew, and I started receiving requests to manage multiple departments in the areas of Beauty, SFX, and Hair Design.
Currently, I am in the process of taking steps towards the next chapter in my career- applying the Local 706 makeup artist union.
Great, so let’s dig a little deeper into the story – has it been an easy path overall and if not, what were the challenges you’ve had to overcome?
I would love to say it was a smooth road for me, but that certainly has not been the case. This career has definitely tested my limits, both as an artist and as a female working in the film industry. As a woman in the industry, I have had many instances where so-called “directors” or “writers” would want to meet with me to discuss a potential project. Because I was so eager for work, I would blindly walk into these meetings only to realize that they were nothing more than desperate attempts to bring a pretty face around their drinking buddies. Of course, this has not always been the case. You learn to wise-up quickly. My advice is to do research on anyone you are meeting with, as best you can. And use your instincts. If it doesn’t feel right, it probably isn’t.
But no matter the gender, I always tell newcomers that you absolutely have to love this job, or you will never survive it! I love what I do. I live and breath makeup! I love creating characters, doing makeup, learning new things and always pushing myself to be the best. I have also come to realize that there is not just one single way to go about doing something in order to achieve the best results. You need to create your own method and follow the path in life that works for you.
Alright – so let’s talk business. Tell us about Renae (Makeup and Special Makeup Effects) – what should we know?
I am a Makeup and SFX Artist, meaning I do beauty/HD Makeup as well as prosthetic makeup, including character designs and sketching, horror makeup, fake body parts, blood gags, wounds, injury simulations, and c02 squibs. I also do hair styling for men and women as well.
People mostly recommend me for horror prosthesis and character work, but I also enjoy the occasional hair styling call.
What I am most proud of is my own brand -“Renae.” It is a lot to take on sometimes. But I have overcome so much and feel that I have grown immensely as an artist over the years. When an obstacle comes my way, I usually step back, reassess the situation and push harder. There is still a lot to accomplish, but in just witnessing my own growth and improvement over the years I am further encouraged to constantly keep evolving as an artist.
Do you feel like there was something about the experiences you had growing up that played an outsized role in setting you up for success later in life?
Growing up school never came easy for me, but I found myself gravitating towards the arts. It was in drawing, painting, and sculpting that I found my passion. From there I decided I would incorporate that into being a Makeup and SFX artist.
- Website: www.RenaeGoodhew.com
- Phone: 574-386-9710
- Email: firstname.lastname@example.org
- Instagram: makeupby_RenaeGoodhew
Renae Goodhew, Morgan Goodhew, Donavan Clark, Renee Gordon , Dana Neumann


Covid Christmas: What can you do to stay safe?
Changes to a planned relaxation of Covid rules for Christmas have been scrapped.
Only people living outside of tier four in England, or in Scotland or Wales will be allowed to meet up indoors on Christmas Day.
Those in tier four in England cannot mix indoors with anyone not from their household including on Christmas day.
BBC News health correspondent Laura Foster looks at what people who are able to meet up can do to reduce the spread of coronavirus.
Read more: Christmas rules tightened for millions


text:
Been working on this on spare weekends and thought I would share. I took my inspiration from this
site and modified it to what I needed (Sketchup is my friend).
Here is a shot of the finished frame mocked up with burners and such.
Spent this past weekend teaching myself to solder copper. Here is the gas manifold, just needs the fittings to connect everything and some real brackets to hold it to the frame.
I bent the flashing for this heat shield by hand, and it most definitely looks like hammered dog crap, that won't do. I have a sheet metal break on loan now so I should get that done a bit more professionally this week (I hope).
I had hoped to use the valves that came with the burners (the ones where you have to keep cranking a timer every 20 min.) as on off valves for automation, but they don't function quite the way I had hoped they would.
What kind of valves do people typically use for this? I've seen them on rigs, just don't know what they are.


NERC Submits Information Filing Related to CRISP OT Funding
- Filter By Electric Reliability Law Blog
On December 23, 2021, in Docket No. RR21-5-000, NERC submitted an Informational Filing in Response to the Commission's Order dated December 2, 2021. The Order directed NERC to explain expenditures and amounts from the Cyber Risk Information Sharing Program (CRISP) used to fund the CRISP Operational Technology (OT) pilot programs, including how NERC plans to spend any unspent funds in 2022. The Order also concluded that NERC should have sought FERC approval to transfer $1 million of unused funding for the CRISP OT pilot programs to a CRISP Special Projects Reserve, rather than crediting the unused funds to CRISP participants against their future funding requirements. In this informational filing, NERC provides the information specified in FERC’s Order and respectfully disagrees with FERC’s conclusion regarding approval for use of the unspent funds.
To view NERC’s filing, click here.


text:
A Tribute to the New Jersey - New York Kink Community.
Devastated by the death of his love, Lynn, Nicholas turned to the community they had become part of: the kink community. He reconnected with some old friends, and through them, met some new ones. Randee was an in-your-face, self-proclaimed slut, and Cassie was an intriguing, intimidating dominatrix. To Nicholas, they were just his friends.
Sometimes sex is just a distraction, but sometimes it can help to heal. For some people, sex is the only way they know how to seek or give comfort. Nicholas found an honesty and acceptance in the fetish community that he did not experience in his vanilla life. After his eye-opening relationship with Lynn, there was no going back. It was time to make new friends.
It's hard to find the right words for a book like Your Kinky Friends that is beyond brilliant. It is a remarkable story that is beautiful and full of love. The honesty of each word and the raw emotions transports you right into Your Kinky Friends. You meet people like Randee, Cassie, Desmond, and a variety of others who are so intriguing you can help but want more time with each of them. It's Nicholas Tanek's excellent writing style that brings this all to life. He makes you feel like you're with him every single step of the way. You feel the grief and vulnerability as he explores the kink community when he puts himself out there. The intimate moments remembering Lynn and the undeniable connection of a love that was perfect for two people. All of these things combined make it unlike any other book.
What makes You Kinky Friends a true standout is that it's a book about the connections among people. It's the friendships and relationships you make, along with the ability to be yourself. It is definitely a book you want to read and experience. There are not enough words to say how much I truly loved this book. I didn't want it to end and I'll be re-reading more than a few times. It's time's like this I wish there were more than 5-stars. Your Kinky Friends by Nicholas Tanek is a book that you'll need and want to read.
Rating 5 Stars

domain: library