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July 17, 2011 Norfolk/Portsmouth, VA to Coinjock, NC
We set the alarm to get up in time to leave at 8:00, but we both woke up before the alarm went off. We pulled away from the dock a little early at 7:45 to make sure we would make the bridge opening at 8:30. Going under our first RR bridge, we came face-to-face with a ship going the other way. He wins! We waited until he came through.
From there, we motored the 5 miles to make our first bridge opening, but…..foiled again! The RR bridge in front of it, which is normally open, was closed for a train. We waited….and waited….for over 30 minutes for the train to arrive and slowly….ever so slowly, it made its way closer and closer to the bridge–then stopped right before it got there! The RR workers got off and poked around the train for 15 minutes before it started to move again. The RR bridge finally re-opened at 9:15, but the bridge tender would not open the street bridge for us. She said there was 15.5′ of clearance enough for us to pass under. When we got up close enough to check the fender boards, we found that they showed a clearance of 16′. We discovered that we could have gone UNDER the street bridge this whole time. With 16′ of bridge clearance (we need 14′ with the antennas down), it was a tight squeeze, but we made it. We hurried over to the Top Rack Marina on the other side of the bridge to fuel up and still make the next Steel Bridge opening at 10:00. We finished fueling and made the bridge opening just in time. From there we had less than 3 miles to go to get to the Great Bridge Lock with an opening for southbound travelers at 10:25. Once we left the Top Rack Marina, it would be all new territory for us. We had come to Norfolk via the Dismal Swamp Route from Elizabeth City, NC and would go back via the “Virginia Cut” for a change of scenery and because it puts us closer to the Outer Banks which we want to explore. The Lockmaster loaded us into the lock with another boat at 10:25, but the corresponding bridge on the other side would not open until 11:00, so we just hung out in the lock while he lowered us 1 ft. and then stayed tied up there until 11:00.
I donned my life jacket (it’s a rule) and Auggie and I got off the boat to walk around. I didn’t spend a lot of time on shore because all Auggie wanted to do was eat the goose “candy” (droppings). It was very pretty there, with many crepe myrtle trees of pink, rose, and purple colors in bloom.
We traveled down the North Landing River (VA Cut) for another 5 miles to Centerville and waited for the Turnpike Swing Bridge to open. It went up really fast.
After that, we motored over another 10 miles of winding river, through 2 more bridges, and on to Pungo Ferry. (Where DO they come up with these names?) The river here reminded me a lot of the Dismal Swamp–lined with cypress trees and stumps, only wider. Since it was Sunday, we encountered a lot more recreational boat traffic along the way. The cypress trees disappeared and gave way to swamp grass and a wider river. Good thing, too, because we had to pass a tug pushing a barge loaded with landing craft.
As we reached Pungo Ferry, there was a group of boaters hanging out at the beach enjoying their Sunday afternoon. A jet skier came up behind us, and jumped over our wake a couple of times for a thrill.
At 1:00 we crossed over the border from VA to NC. The river really got wider as we entered Currituck Sound and slowly motored the last 15 miles to Coinjock—a blip on the NC Cut. It had been nice (85), but humid while we were in the river. Once we got into Currituck Sound, there was a nice breeze blowing to cool things off a little. We had some small waves and whitecaps on the surface of the water. The sky was blue with little puffs of clouds scattered overhead. Once we got into Coinjock Bay, the water calmed off considerably and it was an easy ride into Coinjock, arriving at 2:40. JW, the dockmaster, helped us tie up and we settled in at the dock for the night after a run of 48.9 miles today. Coinjock was named by the Indians for the berries in the area.
Four other boats pulled in after us. A 58′ Hatteras Sportfish pulled in and the delivery captain told us they were delivering the boat to Miami on Thursday. Thursday in Miami? We couldn’t believe it! That includes stopping to have an anchor installed too. They would be running offshore in the ocean from Beaufort, NC to St. Augustine, FL. Amazing! That’s almost 400 miles a day! We watched the Women’s World Cup Soccer game on TV and then went to dinner at the Coinjock Restaurant. We treated ourselves to prime rib and mashed sweet potatoes. Yum!
After dinner, we took Auggie for a walk and checked out the other boats at the dock. We also checked on the weather for tomorrow and the tropical depression #2 that is forming off the coast of FL. Things look pretty good so far. We watched a little cable TV and got caught up on the news. It turned out to be calm, peaceful night.
July 18, 2011 Coinjock to Manteo, NC
We had a leisurely morning and were in no big hurry to leave. We did our thing and got to talking with a boater from MI, who was headed to Chesapeake Bay. We sold him our chart book since we would not need it anymore and he was happy to get it with all my notes in it.
We finally pulled away from the dock at 8:45, heading to Manteo on Roanoke Island in the Outer Banks of NC. I was a pretty day–blue cloudless sky, light breeze, and temperature at 80. We traveled south on the North River to Albemarle Sound–a shallow, but large body of water that can get pretty nasty in even a little breeze, but today it wasn’t bad. We had 1′ waves in the beginning of our 11.5 mile crossing of Albemarle Sound, but soon the water turned glassy and calm.
We passed north over Roanoke Island to Roanoke Sound between the island and the Outer Bank island of Bodie. From there, we entered Shallowbag Bay and Manteo’s harbor. From a distance, we could see a huge sand dune on Bodie Island.
The dunes are part of Jockey Ridge State Park and can be 110-400 feet high. Many visitors come to hang glide from them. When we passed by, we could see at least 3 hang gliders standing on the top of the dune, ready to take flight. We could also see the Wright Brothers Monument from a distance. I read that on top of the 90 foot dune known as Big Kill Devil Hill is a 60 foot granite monument. It is on the site of the world’s first powered, sustained and controlled flight. Orville and Wilbur Wright traveled to the Outer Banks for their flight experiments because of the wind, slopes without trees and sandy soil for soft landings. The first flight lasted 12 seconds and carried Orville 120 feet. The last longest flight lasted 59 seconds and carried Wilbur 852 feet. (My picture isn’t that good.)
We waited for our slip assignment and then entered the Manteo Waterfront Marina. George was there to help us tie up and we were all settled in by 1:00.
We hung out for awhile and then took Auggie for a walk into town.
Manteo is near the site where, over four hundred years ago, the First English colony was born on American soil–then mysteriously disappeared. Over 100 years ago the Town of Manteo was incorporated and named in honor of an Indian Chief who befriended that “lost colony”.
He got tired and hot so I took him back to the boat and Bob and I walked around the area by ourselves. Our first stop was the Roanoke Marshes Lighthouse.
From there we walked over to the Maritime Museum, up and down the streets checking out the shops, restaurants, and over to the marina.
We spotted the Elizabeth II, a 16th century sailing ship across the marina. It’s a representation of the merchant ship that Sir Walter Raleigh used to establish England’s first New World colony at Roanoke Island. The settlement took place 20 years before Jamestown was established. It was established between 1585-1587.
Bob and I returned to the boat to have cocktails before dinner and spend some time with Auggie. We checked on the weather. We were especially interested in tropical storm, Brett, and where it was going. It doesn’t look like we will get much of anything, but a little wind. We hope to be inland by the time “he” arrives. Auggie and I sat out back in the boat and watched people go by. We took a walk down the waterfront and into town past the Tranquil Inn, a very quaint local hotel.
Back at the boat, we watched a little TV and called it a day. Tomorrow we’ll take a bike ride and explore the area. I want to check out the shops as well. Our trip today took us a total of 82.1 miles.
July 19, 2011 Manteo, NC (day 2)
We enjoyed “sleeping in” knowing we had nowhere to go. Bob made us eggs for breakfast. What a treat! We spent about 4 hours planning our trip for the next 5 days. We have to consider the winds from Tropical Storm Brett which are starting to affect the area and the heat….temps inland are in the upper 90’s, but are in the lower 90’s near the shore. Tack on the humidity and the heat index really rises. We need to have AC in those kinds of temps. We made our tentative plans for the next 3 days and then we’ll re-evaluate. After lunch, we took a bike ride along Wingina Avenue north to Roanoke Gardens on Mother Vineyard Road. The neighborhood is known as Mother Vineyard. In this neighborhood grows the largest scuppernong grapevine on the island which dates back to the 1500s.
We did the loop through the neighborhood which took us past the shore with views of Roanoke Sound, Nags Head, and Jockey’s Ridge. The route took us back to the bike path and back along the main highway. We were gone an hour or two and then we went back to the boat to cool off. Bob took me shopping for my anniversary gift and then went back to walk Auggie. I took some time to walk around town and check out the shops. The day was heating up and the afternoon winds had increased. The sky was mostly cloudy and it looked like it might rain. Rain would be a welcome relief. We hung out and tried to stay cool the rest of the afternoon. Tomorrow we hope the winds are favorable for traveling south. It never rained and we turned in early to get an early start.
July 20, 2011 Manteo Waterfront Marina to Dowry Creek Marina (Belhaven, NC)
We wanted to get an early start to beat the winds and the heat, so we left at 7:30 to eventually head south down the Alligator River.
The skies were clear and the temp was already 80. The breeze had started blowing about 4 AM, but there was not yet the 10 mph winds they were predicting. We were somewhat protected from the wind as we made our way around the top of Roanoke Island, but once we turned down the Alligator River, we headed right into the southerly wind that had generated some waves. We almost had a HUGE delay when the Alligator River bridge tender told us he couldn’t open the bridge because a barge was doing some work there. Lucky for us another boat going north requested an opening too, so we were both able to pass through without a problem. I personally think the barge was not an issue…..just a bridge tender who had an attitude problem. Either way, we continued on after only a few minutes of delay. We entered the Alligator/Pungo River Canal at 11:45 and motored at 10 mph for the 21 miles of narrow canal. We had traveled 18 miles at cruise speed through the wide river itself.
We reached the southern end of the canal at 1:45 and entered the Pungo River continuing on another 6 miles to our destination, Dowry Creek Marina, for the night (just 4 miles east of Belhaven). If there was any big wind today, we didn’t feel it much or see it in the waves. The last 4 miles on the water were like glass.
We had a very pleasant run today of 75.7 miles in 7 hours and arrived at our destination at 2:15. We were tied up, sittting in the AC (the cockpit thermometer read 96), and sipping a cold beverage by 2:30.
We went to check in and look around. The office is in a two story building which includes the laundry and showers.
There is a nice pool and boater’s lounge on the grounds. The owner had some very interesting artwork (bottle tree) on display that she created.
The marina was mostly empty except for a few boaters who helped us tie up and the docks were in a weird configuration, but the rest of the place was very nice.
After about an hour at the dock, we felt the wind pick up and heard thunder outside. In checking the sky, we could see lightning flashes and a possible storm approaching from the northwest. Would we get some needed rain today? It did rain lightly for about 10 minutes, but not enough to rinse off the salt from the boat. After we cleaned up, we made dinner and relaxed with a DVD. We were all drained of energy from the heat today and just wanted to relax the night away. The wind picked up as we went to sleep, but that didn’t deter us from slumberland. We both fell fast asleep.
July 21, 2011 Dowry Creek Marina (Belhaven) to Sea Gate Marina (Morehead City), NC
Walking out of the door this morning felt like a blast from a sauna. The humidity must have been 100% since nothing dried from the short rain shower we had yesterday. Bob go up before I did at 5 AM and I followed at 6:30. We wanted to be gone by 7:30 before the wind came up and pinned us to the dock. We were wedged in a corner of the marina and might have a difficult time leaving if the wind is up. We pulled lines early and Bob, with his expert driving skills, backed the boat away from the dock and all the way down the narrow lane to where he could spin the boat around and pull out. It was very hazy with a light breeze from the SW. We were traveling into the wind which would be our saving grace. We were all alone out there until we got near Hobucken, when we passed a sailboat and a Coast Guard boat going north.
There is a Coast Guard station there, along with an collection of shrimp boats and a commercial fish market.
Bob saw a small boat fueling up there, so he yelled over and asked the price of gas. It was $3.65/gal. so he made a quick decision to stop and fuel up. While we were fueling up, a fisherman came in with his catch of 100 flounders.
It was a busy place for everyone but the shrimp fishermen. Their boats were in port and broken down they said. We were in and out of there in about 20 minutes. The water continued to be glassy until we hit the notorious Neuse River.
We were going south against the wind and the 1-2′ waves. It would have been a wet ride, but we ran at cruise speed to keep the boat dry. The Neuse River can be nasty in a strong wind, but we were lucky it wasn’t bad like they predicted. We decided to change our plan of stopping at River Dunes Marina near Oriental, NC (1/2 way down the Neuse River) and go the entire way, stopping at Sea Gate Marina at the bottom of the river. River Dunes Marina was our place to stop if the Neuse River conditions were bad today. We decided to do the whole Neuse River passage since the conditions were comfortable. Auggie slept on the seat by my side the whole way and shared my fan with me. We tucked in close to the shore and it got calmer yet.
Today we saw a lot more cruising boats traveling north than we have seen in a long time–6 sailboats and 4 trawlers. Most of them had home ports somewhere along the east coast. Maybe they were “loopers” finishing up the Great Loop and returning home. As we left the Neuse River and entered Adams Creek, the breeze died and it was sweltering hot. We listened to the NOAA marine weather forecast and there was a heat advisory warning out for all of northeastern N. Carolina through Saturday. The temps for us near the coast are a little cooler than further inland with a high today of 88 (heat index of 103). I don’t know if they made a mistake in their report, but they also said the temp in Washington, DC would be 91 with a heat index of 127. Wow! Can that be correct? We arrived at Sea Gate Marina at 1:15 and we were done for the day. AC here we come!
We checked in at the office and found out where all the facilities were. I decided to do some wash since it was cheap and convenient to the boat. We hung out in the AC most of the afternoon and Bob went outside to cook dinner once it cooled off a little (if that’s possible). We would head off to Morehead City tomorrow. We had stopped across the river at Beaufort on the way up, so we would give Morehead City a try on the way down. At least that’s our plan for now.
July 22, 2011 Sea Gate Marina to Morehead City, NC (Yacht Basin)
We poked around this morning after getting up at 7:30 because we only had a few miles to go to get to Morehead City where we would spend the next 2-3 nights. We pulled away from the dock at 9:20 after the winds had already started to blow strong out of the SW.
The next 3 days are predicted to have strong winds from a low pressure system that has been stuck in this area for over a week. This system has brought high temps into the upper 90’s to many areas in NC with high humidity. It is expected to move on out of here on Monday. I know other parts of the country are experiencing some of the same record temps and even hotter, so I can definitely relate. We had a short stretch of open water to cross this morning before we got to our destination and that was enough to make us glad that we had traveled down the entire Neuse River yesterday instead of saving half of it for today. The winds were stronger today and very gusty, starting very early in the morning. Our short 10.3 mile ride got us wet and salty and we were concerned about docking in the marina with the wind. Bob did some expert driving and brought us safely to the dock at 10:30 with the help of the dockhands who caught our lines.
We were content to stay tied up for the next couple of days until the conditions improve. We checked in at the marina office, got our bearings, some restaurant recommendations for our anniversary dinner on Sunday, and sat down to have lunch. After lunch, Bob gave the boat a thorough washdown while I spruced up the inside with a little vacuuming and cleaning. Later, Auggie and I took a walk to check out the grass in the area. It doesn’t take long to get hot and sweaty outside, so we didn’t stay out long before we were back at the boat and in the AC. Later, Bob and I took a walk down to the nearby convenience store to see what they had. We walked to the waterfront along the ICW to see what the water conditions were. There were white caps and 1-2′ waves rolling in.
Some people were enjoying the day in the water at the island along the ICW. That seemed like the place to be in this heat.
We walked along Arendell St. to the Ruddy Duck Tavern to check out their menu. We were scouting out a place to have dinner for our anniversary.
We decided to have a beer and some nachos. Then we’ll skip dinner tonight or maybe have a sandwich later. After returning to the boat, I took Auggie for a walk and then went to clean up. We would just hang out until the sun went down, taking the heat of the day with it. Tomorrow is supposed to be windier, but we’ll find something to do to stay cool.
July 23, 2011 Morehead City, NC (day 2)
Yesterday made me crazy! I couldn’t take the heat anymore. It was too hot to do much and there were things I really wanted to see and do. I was bored just hanging around. I vowed to have a better day today. It was a little hotter today and windier….if that’s possible. We got to sleep in and have a relaxing breakfast. We did some trip planning and remembered some places that we needed to go back to that we skipped the first time. We also made plans to take a ferry tour over to Cape Lookout Lighthouse and Shackleford Banks Island where the wild ponies run. We had wanted to take our own boat out there and anchor in Lookout Bight, but the weather wasn’t cooperating and I was bummed out about that. This tour will be one way we get to see and experience the same things. We gave Auggie a bath which he loved! I think he was enjoying the cool water. Later when he dried, we gave his beard, face, and paws a trim. He is so cooperative for his haircut. I think he really likes it! Around 2:00 we decided to take a walk over to the Ruddy Duck for their cheap beers and to check out the boats and people on Sugarloaf Island. We got a good seat at the bar to see all of the action out on the water…..and there was a lot of it, even with the strong winds.
We had a beer and some calamari before we walked out on their pier to view the action. We walked a little farther down the waterfront to check out the city marina and a few other eating establishments. Bob sat next to King Neptune and asked him for some favorable boating weather. Let’s hope he listens.
Just that short 10 minute walk made us all hot and sweaty. At least the breeze by the water kept us from thinking how hot we really were. We grabbed Auggie once we got back to the boat and went up to the boater’s lounge. From the second story lounge, we could get a good view of our boat and the marina.
We were the only ones up there, so Auggie got to be off his leash and walk around to explore the area. Bob and I found a Harry Potter movie on the TV, so we hung around to watch it for awhile.
When it ended, we went back to the boat to make dinner and wait for the sun to go down. We took Auggie out for his evening walk before relaxing with some TV.


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San Antonio Film Festival is an accessible and inclusive platform for cinema artists, brings cinematic culture to a diverse audience and showcases films from around the world while educating and encouraging emerging filmmakers of all ages.
Ska-punk royalty Sublime with Rome, hip-hop icons Cypress Hill, and reggae-rock party animals Pepper pool their crowd-pleasing talents to devise a surefire prescription for the summertime blues. Carrying on the legacy of legendary singer Bradley Nowell, dead-ringer Rome Ramirez leads Sublime with Rome through energetic numbers from its newest record, Yours Truly, as well as rock-radio mainstays, such as “Santeria” and “What I Got,” that still dominate airwaves with a contagiously laid-back attitude. Multiplatinum hip-hop group Cypress Hill continues to meld worldly genres and salute organic gardening in hits such as “How I Could Just Kill a Man” and “Insane in the Brain.” Heading up the summer fun pack, the Hawaii and California hybrid of Pepper stomps and grinds with goodtime odes to love and pogo sticks, as heard in their song “Give It Up.”
A direct descendant of the 1891 flower-chucking commemoration of the Battles of the Alamo and San Jacinto, Fiesta San Antonio illuminates the cultural depth and noble past of the city. Fiesta commission membership benefits include an exclusive membership pin or ladder bar for each year of membership, a copy of the Fiesta magazine, participation in the commission's annual membership meeting on May 24, a 15% discount on official merchandise at the Fiesta Store, and a limited-edition medal.
For three days in November, the Weihnachtsmarkt Christmas Market brings Olde World Christmas spirit to New Braunfels. Vendors set up cheery red and green booths in the German-style holiday market, where they sell homemade wares such as aromatic roasted nuts, unique toys, vintage cameos, and homemade toffee. Nearby, authors sit ready to discuss their novels or sing their favorite Christmas carols at the on-site book fair and a jolly Santa eats breakfast with kids of all ages. To keep guests warm during the event, Sophie's Cafe serves up warm mugs of soup paired with sandwiches or tempting desserts.
Proceeds from the event benefit The Sophienburg Museum and Archives, which serves as the hub for immigration ship logs, photos, and documents of the first German Americans who found their way to Texas.
Since 1920, the expansive fields of San Antonio Polo Club have hosted scores of dignified clients as they’ve learned and mastered the noble sport of polo atop equally noble steeds. The club’s staff inducts newbies into the elite ranks with beginner polo lessons, hosts more experienced players in open-play sessions, and challenges advanced patrons to compete in tournaments or to learn to play the horse’s role. Due to the club’s history and commitment to introducing polo to new generations, it has been featured in the Museum of Polo and Hall of Fame.

domain: artistic


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Mangaluru: The National Investigation Agency (NIA) conducted raids at several places throughout the City on the morning of Thursday September 22.
The raids began at the same time at around 3.30 am at locations linked to PFI and SDPI, including the Kavoor, Bajpe, State Bank, and Kulai areas.
According to sources, the NIA detained over 60 activists amid protests.
The raid was held under heavy security.
As soon as the raids began under heavy police security cover at the head office of the SDPI on Nellikai Road in Mangaluru, hundreds of workers of SDPI gathered at the spot and demanded that the NIA should stop the raids. They also raised ‘go back’ NIA slogans.
Mangaluru Police Commissioner N. Shashikumar rushed to the spot with additional force. After the protesting group failed to get convinced, the police cracked down on the group and took more than 60 into custody and dispersed the crowd.
Meanwhile, Police Commissioner Shashikumar appealed for the people not to heed to news being circulated on social media. “We are vigilant on messages that are being spread to create confusion.
The raids are being conducted in the backdrop of the murder of BJP Yuva Morcha activist Praveen Kumar Nettare near Mangaluru recently. Chief Minister Basavaraj Bommai and Home Minister Araga Jnanendra have repeatedly stated that they will go to the roots of the well-oiled network which is indulging in hacking Hindu activists to death.
Inputs from IANS

domain: news


Expensive heart procedure failed to reduce the risk of death. Doctors said Monday that angioplasty plus stenting a common, expensive heart procedure plus the best medical treatment failed to reduce the risk of death or heart attacks, when compared to optimal medical treatment alone.
In the blockbuster COURAGE Trial, doctors at the 56th annual scientific sessions of the American College of Cardiology said that the $38,000 angioplasty-plus stent heart surgery now done a million times a year in the United States with the goal of freeing patients from chest pain did not, in the long run, even result in less pain.
“There are hundreds of thousands of Americans who are currently getting stents placed who do not need it as initial therapy,” Dr. Raymond Gibbons, professor of medicine at the Mayo Medical School in Rochester, Minn., and president of the American Heart Association, told United Press International.
If you treat people vigorously and coach them and they get their blood pressure under control
Thomas Ryan, senior consultant and emeritus chief of cardiology at Boston University, agreed.
“This study shows that, if you treat people vigorously and coach them and they get their blood pressure under control, patients can do just as well on medical therapy,” he told UPI. But, he cautioned, “They can’t just take a pill. This is hard work. They have to get out and exercise. They have to get maximum doses of lipid lowering drugs,” he said.
Originally scheduled for simultaneous release at the ACC meeting and in the New England Journal of Medicine on Tuesday, the organizations reported the findings Monday after major portions of the report were leaked and were published online in various publications.
“Our findings parallel those reported in recent trials,” said William Boden, chief of cardiology at Buffalo General and Millard Fillmore Hospitals. “In the aggregate, these studies, including our own, include outcome data on more than 5,000 patients and show that percutaneous coronary intervention angioplasty plus stenting has no effect in reducing major cardiovascular events.”
The procedure does relieve pain in patients with angina, or chest pain
Mayo’s Gibbons said that the procedure does relieve pain in patients with angina, or chest pain, and still is the treatment of choice in people who have uncontrolled angina, a condition marked by pain even when at rest that is not well-controlled by use of drugs such as nitroglycerine.
Angioplasty with stent implantation is also recommended to open up coronary arteries in people in the throes of an acute heart attack. Such procedures can be lifesaving in these patients, he said.
In the COURAGE study, Boden, also professor of medicine and public health at the University at Buffalo School of Medicine and Biomedical Sciences, and colleagues across the United States and Canada recruited 2,287 patients who had evidence of heart disease.
The researchers randomly assigned 1,149 patients to undergo angioplasty-plus-stent
Between 1999 and 2004, the researchers randomly assigned 1,149 patients to undergo angioplasty-plus-stent and to receive optimal medical therapy and 1,138 to receive optimal medical therapy alone.
The primary outcome of the study was the composite of death from any cause and nonfatal heart attacks. There were 211 such cases in the patients who received angioplasty and 202 patients in the medical-therapy-only patients.
After about 4.6 years, about 19 percent of the patients who received angioplasty as an initial treatment experienced that primary outcome, compared with 18.5 percent of the medical treatment group a difference that did not reach statistical significance.
Similarly, regarding rates of heart attack, stroke or death the trial’s secondary endpoint patients who got drugs and stents experienced these events at a rate of 20 percent, versus 19.5 percent in the drugs-alone group.
Angioplasty plus medical treatment would prove superior than just medical therapy alone
Boden, speaking at a press briefing Monday, said that one of the surprising findings of the study was that by five years, there was little difference between the groups among patients who were angina-free 74 percent of those having angioplasty and 72 percent of those following medical therapy.
“We set this study up with a hypothesis that angioplasty plus medical treatment would prove superior than just medical therapy alone,” he said. “We wanted to give stenting the best chance to prove it had more benefits.”
In angioplasty, doctors make a small incision in a patient’s leg, allowing access to the main artery in the leg. Into that artery a balloon-tipped catheter is inserted. Using X-ray guidance, the catheter is advanced through the arterial system until it reaches the coronary arteries.
When these arteries become blocked they can cause chest pain or heart attacks. The catheter is positioned at the point of coronary artery blockage and the balloon is inflated, crushing the blockage against the walls of the artery and opening the blood vessel.
To make sure blood keeps flowing, doctors then implant tiny mesh coils known as stents to act as scaffolding that props open the blood vessel.
Despite Monday’s news, doctors were quick to note that stents still have a place in cardiac care.
We shouldn’t lose sight of the fact that revascularization angioplasty can be beneficial
“We shouldn’t lose sight of the fact that revascularization angioplasty can be beneficial in acute situations,” said Sidney Smith, professor of medicine at the University of North Carolina. “However, the foundation for all our work should be comprehensive medical therapy. If you get patients to take their medicine and treat to prescribed levels, patients can have benefits.”
Jim Dove of Springfield, Ill., president-elect of the ACC, promised that the organization will consider sanctions against those individuals who were responsible for breaking the embargo on release of the study.
Steve Nissen, director of cardiovascular medicine at the Cleveland Clinic, and current ACC president, told UPI, “We are discussing sanctions. We will do what we think is right, but we will not do it rashly. We consider the embargo process an important part of the integrity of our studies.”


IT’S looking increasingly unlikely that goalkeeper Vedran Janjetovic will play for Sydney FC again, as the air around his “extended personal leave” turns a bit unpleasant.
Sydney are distinctly unimpressed with how the saga has played out, even though Janjetovic, with the assistance of the players’ union, has been signed off on stress leave after losing his first-team place to Danny Vukovic.
What has also emerged is that players who are sidelined through non-physical reasons aren’t covered by the A-League’s injury insurance policy. So even if a player is deemed unfit to play for months, a club could only sign an injury replacement by spending more on wages.
Far-fetched as it may seem, some cynics in clubland fear that in future, a player who wanted to leave a club could use this to their advantage, especially at a club that wasn’t one of the richer in the league.
Meanwhile there has been some discussion over Janjetovic’s future between Sydney and the Wanderers, though Sydney are adamant they won’t let him leave without a viable No 2 coming — such as Andrew Redmayne at Western Sydney.
● ● ●
SYDNEY FC stayed at a posh Melbourne hotel the night before the FFA Cup final — the sort where attention to detail is taken seriously.
So was it really a coincidence that two Sydney players received unsolicited alarm calls at 6am and 6.30am on the morning of the game?
Perhaps the concierge was a City fan.
● ● ●
ALL the Sydney FC players looked morose the next morning, as you’d expect after losing a cup final.
Which might be why several of them barely got onto the plane home to Sydney in time, and received a mild ticking off from the Qantas stewards who had been calling for the missing passengers.
Only a nasty-minded cynic would suggest that a couple had already gone missing, from about 7.45pm the night before.
Originally published as Janjetovic’s Sydney FC career likely over


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US: Columbia Sportswear urges court to dismiss lawsuit
By Katie Smith | 23 July 2012
Outdoor apparel and footwear firm Columbia Sportswear has urged Lane County Circuit Court to dismiss a lawsuit claiming the company used Innovative Sports' technology to produce heated clothing.
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Arizona Public Service has a majority on the Corporation Commission
KVOA.com reports. Bob "Texter" Stump and the APS duo, Tom Forese and Doug Little, are all saying they have no conflict of interest and thus will not recuse themselves from voting on APS matters. That gives APS a 3/5 majority on the Commission.
Goes to show ya: honest politicians are those who stay bought.
Laurie Roberts' column on this is a must read, if for nothing else than for this amazing conclusion.
Stump, by the way, insists he also has no conflict. SunRun, a rooftop solar company, has asked that he recuse himself, given his Facebook posts expressing hostility toward solar.
Stump, in his response, says he’s totally open minded and besides that, he was engaged in “satirical writing” and besides that, anything he writes on Facebook is private.
“The entry into the public docket of personal Facebook photos – my page is a private, not official, page – was a gratuitous invasion of my privacy,” Stump wrote.
Stuff you post on Facebook? Private?
Folks, you just can’t make this stuff up.


Wednesday November 25, 2020
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MPs get remote work option except for voting
Published : 25 Mar 2020, 00:38
Updated : 25 Mar 2020, 10:07
Members of the parliament are now permitted to carry out their parliamentary work remotely by using digital tools.
The Speaker’s Council on Tuesday took the decision in line with the Emergency Power Act currently in force and to prevent the spread of COVID-19, said an official press release.
The lawmakers may follow parliament’s work and leave legislative initiatives digitally, but not vote.
Working remotely is recognised as parliamentary work similar to working being physically present in the parliament, if notified of beforehand, the release said.
Only necessary meetings of the parliamentary committees are held. Meetings of committees and parliamentary groups have been moved to larger spaces, including auditoriums, and expert hearings are executed remotely or through written statements.
Committees can organise unofficial meetings remotely, if necessary, for these hearings.
To ensure quorum, the Speaker’s Council has asked the committees to make a motion on choosing additional alternate members.


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Oklahoma Paralegal Degree Programs
Universities and colleges in Oklahoma with paralegal undergraduate (diploma, certificate and bachelor) and graduate (Master) legal assistant degree programs.
| University/College Programs | Paralegal | Oklahoma |
Oklahoma Paralegal and Legal Assistant Education
East Central University - Legal Studies Program - Ada
East Central University offers a Bachelor of Science degree in the Legal Studies program. It prepares students to enter the paralegal profession by teaching them theoretical and practical aspects of the subject. The professors are practicing attorneys and they help enhance analytical and communication skills of students. There are scholarships available for deserving students.
Rose State College - Legal Assistant Program - Business Division - Midwest City
The Rose State College, Oklahoma offers the Legal Assistant Program – Business Division, which is an Associate Degree Program in Applied Science. A two-year course, the program has two admission mandates of which any one can be met to secure a position with the university’s paralegal course offering. The same is approved by the American Bar Association.
Associate of Applied Science
Tulsa Community College - Legal Assistant Program - Tulsa
How About getting a job as a paralegal at $17.94 per hour? It is possible with Tulsa Community college placements. The students are skilled in their task and know exactly what to do as paralegals. If you want to join their league, come to this college to fulfill your dreams.
University of Oklahoma Law Center - Legal Assistant Education - Norman
The University of Oklahoma Law Center was established in 1909 in the state of Oklahoma. The Law Center was recently voted one of the 15 best law schools in the country and it offers a number of law-related courses and programs, including a legal assistant program.
University of Tulsa - Legal Assistant Program - Tulsa
Students at the University of Tulsa have a choice in the timings of certificate program in paralegal studies. They can either take day classes or evening classes or combine both. Thus, working students can pursue the program without having to sacrifice their jobs.

domain: law


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Main / Shopping / Minecraft ps2 edition
Minecraft ps2 edition
Name: Minecraft ps2 edition
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Grandma Loves You! Hardcover – July 1, 2013
"Rebound" by Kwame Alexander
Don't miss best-selling author Kwame Alexander's "Rebound," a new companion novel to his Newbery Award-winner, "The Crossover," illustrated with striking graphic novel panels. Learn more
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From School Library Journal
PreS-K-While it is a truism that nothing beats the love of a grandparent for a grandchild, it is usually something that children themselves take for granted. This book, clearly aimed at the grandparent market, ensures that this love is front and center. Using simple rhymes, a grandmother rabbit celebrates her love and affection for her baby's baby in a slightly over-the-top paean to the little bunny. The lush, full-color pastel watercolors feature cozy scenes focusing on the anthropomorphized family members and are framed by flowers, butterflies, and fields of green. The last three pages have spaces for a child's name, photos, and a letter from the grandma to her grandchild, making this more of a gift book than a library purchase.-Marge Loch-Wouters, La Crosse Public Library, WIα(c) Copyright 2013. Library Journals LLC, a wholly owned subsidiary of Media Source, Inc. No redistribution permitted.
Tenderhearted affection is displayed through the softly hued watercolors of furry, cuddly rabbits and is combined with gushing verse recited by one delighted grandmother bunny to her sweet and innocent grandbaby. "The moment I saw you, / I fell in love, / Honey, my bunny, / my sweet turtledove. // Wiggling and giggling, / you captured my heart. / I loved you so much, dear, / right from the start." Love at first sight deepens as the pages turn, becoming that special relationship of mutual devotion unique to a grandmother and grandchild. While this displays no shortage of greeting-card syrup in its sentiment, its gentleness will make for nice initial read-aloud sessions for the intended audience and an appropriately thoughtful gift from any new grandma to grandchild (as blank lines for inscription, a "special letter" to the grandchild and a picture of grandmother and grandchild attest).
An unabashedly idealized but nevertheless wholehearted hymn to grandmotherhood (Picture book. 2-4)"
If you buy a new print edition of this book (or purchased one in the past), you can buy the Kindle edition for only $2.99 (Save 57%). Print edition purchase must be sold by Amazon. Learn more.
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Hopefully the books will be a keepsake of his first Christmas and a story we can read him over & over! 💓

domain: literature


cale: 1:64/ Length: 31.61″/ Height: 22.24″
Marseille is a 1764 French schooner. Reconstruction was carried out on original drawings of that time of a ship meant for shooting training. She is equipped with 24 three-pound guns mounted on a special gun-carriage fixed on the board-side and with other 2 guns of retreat of the same gauge. Characteristic are the 2 six-pound fighting guns equipped with a gun-carriage without wheels sliding on a special guide free with a rotation of 180 degrees.
The Mamoli Marseille kit features the following:
A Double planked on bulkhead /hull construction using Lime and Walnut strips, pre cut frames and keel, deck planked in tanganyika, fittings made from brass, walnut, boxwood, and beech, wooden masts and spars, brass cannon barrels, rigging cord and silk flags. Full size plan sheets and a multi language instruction manual.


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LaDainian Tomlinson added: That’s a character flaw to me.
2005 NFL Draft:
- Though the Twins won five of their next eight, the damage was done Wholesale Jerseys NFL and Minnesota started planning for the future;
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The question is: Which areas?
The After a franchise-first Cup Final appearance 2016, the San Sharks took a step back last year.
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For every success story like Casemiro or Vallejo, there Wholesale Jerseys Usa are more that go awry.
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With coming off underachieving , Mrazek could break away and start at least 50 , which he did 2016 and 2015 .
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Gall is moving around quite a bit, but Brown lands a couple of punches.


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Hi guys so it been a while :) I recently had to strip my motor (CA18DET) due to cambelt snapping and apon doing this I noticed that there was signs of detonation on cylinder number 2 :( not sure what caused it guessing it might be a bad injector but thats a discussion for another day. My motor seems to be very knock limited so I would like to look into running E50 now my fuel pump can handle e85 and I can get hold of 800cc DW injectors I'm keen to push for a lot more power once I have rebuilt the motor. I've heard many pros and cons about ethanol. My questions are as follows:
1. What else do I need to change in order to run e50?
2. My car stands for 2 to 3 weeks at a time, will my e50 mix separate or absorb water into the tank causing a fuel starvation of some sorts?
3. Do I need to put any additives into E50 for lubrication?
4. Will I need to service my car on a more regular basis?
1: You should consider adding a flex fuel sensor like the GM 13577379 (Personally I would never run a blend without it)
2: It's not recommended to let ethanol in your tank for a long period of time. However, if you live in a very dry zone it should not be a problem.
4: Normally no.
As a side not, you should read this :
Just to add to what Ludo has mentioned, the amount of moisture the fuel will absorb is totally dependent on the humidity in your area. If humidity is very high, even 2-3 weeks will potentially allow the fuel to absorb a reasonable level of water.
E50 shouldn't require anything special in the way of maintenance. If you are running high ethanol percentages and a rich mixture often you will find that the oil ends up diluted with alcohol. This may require slightly more regular oil changes.
has any one looked into adding a desiccant type breather onto a fuel make to assist in moisture removal?
might assist with long term fuel storage, you would also need to fill the tank using a water removing funnel...


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seize the rebel couriers on the McMinnville and Shelbyville road, and reconnoiter the country for 3 or 4 miles in all directions.
The other two regiments of Colonel Long's brigade, with the artillery, followed General Palmer's division. When the head of General Palmer's column reached Hollow Springs, Colonel Long occupied Lumley's Stand, 4 miles in advance, a very barren country, but an important strategic point in our movement. From it we could strike to the rear of Beech Grove, on the Murfreesborough and Manchester pike, and facilitate the advance of General Thomas' corps against the rebel position there, or move at once on Manchester. Either of these movements my command could have made the same day, because the distance already passed (from Bradyville to Lumley's Stand) was only 10 miles, and the distances from Lumley's Stand to Beech Grove and Manchester were, respectively, 8 and 11 miles. But no order was given for a forward movement. On the contrary, my command was ordered to encamp at Hollow Springs with General Palmer's division, except one regiment, left at Lumley's Stand to occupy that point. During the whole day we heard heavy cannonading from time to time in the direction of Beech Grove.
On the morning of the 26th [June], I was ordered to move to Lumley's Stand, send out scouting parties, and stay there. During the whole day we heard cannonading on our right, on the Manchester pike.
We remained at Lumley's Stand until 2 p. m. June 27, when I received orders to move to Pocahontas, 5 miles from Lumley's Stand, toward McMinnville, and to remain there until both divisions and trains of General Crittenden's corps should pass Lumley's Stand, thus protecting the left of his column from rebel cavalry, supposed to be at McMinneville, or in the direction of Woodbury.
But while at Pocahontas, at 1.30 a. m. June 28, I received orders from the general commanding the department to move at once to Manchester, where I arrived at 9 o'clock the same morning, and found the whole corps of General Thomas there.
The road between Cripple Creek and Hollow Springs being very hilly, and it being rainy weather all the time, my command remained without trains until we moved to Pocahontas, and these to Manchester. Thus the left column of the army to which I was attached, instead of being first in Manchester, on account of different causes, arrived there one day later than the central column.
On the same day, after my arrival in Manchester, by order of the general commanding the department, I sent two battalions-eight companies-of the Second Kentucky Cavalry on picket duty, on of these battalions being sent to Hillsborough. I was ordered to send two battalions more, which I did from the Fourth Ohio Cavalry.
The next day I sent two battalions-eight companies of the First Ohio Cavalry-to relieve the pickets, instead of which these battalions were retained on the front also.
The next day General Garfield telegraphed to Generals Brannon and Thomas to send back to camp half of the cavalry force that was on the front, and ordered me to send one battalion forward to re-enforce the remaining half. I sent one battalion of the Third Ohio Cavalry to the front, which, like the others, was accepted, but no cavalry was sent back to camp. In this manner the whole brigade was scattered by battalions, under command of majors and lieutenant-colonels, on the front of the two army corps, the regimental commanders and the brigade commanders remaining in camp with twelve companies of different regiments, and at the head of all was the division commander himself.

domain: history


Article: When They Arrest Black Grandmothers....
By: Nard Enzi.
"Security" is a broad canvass upon which any number of definitions can be painted.
In the hands of humane, humanitarian professionals, it is a supportive service provided to enhance and protect society, with a stated goal of minimizing violence and other negative outcomes in the performance of duty.
In the hands of racist police officers who arrested Mrs. Marlene Marten, a 73-year-old Black Louisiana grandmother/church elder suffering from diabetes, thirst and hunger, it means detaining someone clearly not a threat to public safety or private property.
In hurricane Katrina's wake, the basics of life became a hundred meter dash and while not swift, her plight nonetheless attracted the worst kind of attention.
To paraphrase rapper/actor Ice Cube, her " skin was her sin."
American domestic security doctrine has always been, as illustrated in the original "In The Heat of The Night" movie with Sidney Portier, a matter of locking up the handiest Negro without details like actual guilt muddying the waters.
Can anyone imagine a White female senior citizen with Mrs. Maten's issues suffering the same callous fate?
The officers involved would face termination and/or criminal charges. Regrettably, 21st Century propaganda aside, African-Americans are still essentially runaway slaves subject to the heavy hand of the law whenever someone chooses its misapplication.
Added insults to injury are Black officers in integrated police departments who impotently stand by and allow gross miscarriages of justice to occur.
After the trouble civil rights organizations undertook to institute Black police officers, can anyone honestly state their existence helps anyone but their employers and the biased status quo?
When LAPD tormentors were lynching Rodney King, Black police officers were on scene and did what is always done while observing civil rights violations- nothing!!
Police officers are not just mindless arrestors, though too many have this mindset. The same discretion used to prosecute is the same discretion to intervene on behalf of innocent citizens whose color outweighs their innocence.
When some sink so low that even our grandmothers aren't safe from latter day Black Codes, who will protect them?
Impotent Black mayors who can't control there police chiefs and seem unable to demand outside investigations?
Black council members for cities and counties whose agenda doesn't include social justice, despite speeches to the contrary?
Black media outlets too focused on entertainment or high society coverage to expose the injustice that gave rise to them in the first place?
Black civil and human rights groups whose activism centers around fine award dinners and attaboy relationships with blue bloods who deny equal opportunity with relish after donating pennies on the dollar to these causes?
In the name of security Black people are being trampled.
In the name of security our tenuous grasp on personhood and possessions, including life itself, is decided daily by those programmed to "keep us in our place."
Mrs. Marten could be any of our grandmothers. Her character, good name and Christian walk mean nothing to someone who views Blacks without badges or titles as cattle to be corralled.
Is it too much to hope that the charges against her are dismissed? Is it unreasonable to request she be compensated for false arrest and malicious prosecution, by the state and/or the US government?
Dare I ask the unthinkable: that the arresting officers face federal civil rights charges for what she was deprived of personally and by extension, her entire ethnicity in this nation?
These cases highlight my choice not to become a police officer. As a security consultant, I get to craft policies specific to the populace with whom I'm interacting.
As a slick sleeved new recruit up to Sergeant, I'd be another faceless instrument of directives devoid of my input.
The future of public safety for African-Americans must include a major role for private security. By "private security" I don't mean underpaid, under-empowered souls who seem to need protection instead of providing it.
My security method involves bonding with the client and even troublemakers. Since social control isn't my goal, there is no "show of force" needed to establish that I am there to serve the interest of safety and success.
While reasonable force is an option, it is so low on the totem pole that it isn't the first choice.
This method has been tested in challenging scenarios I nickname "thug management." I've dealt with inner city patrons who responded quite well to respectful treatment. They are used to disrespect at the hands of law enforcement so its opposite comes as a surprise.
This is the crux of the private security solution for my community.
Private security for Blacks, as I envision it, would become a hybrid of contemporary community associations and security companies devoted to intervention and uplift, while also providing placement in the less caring custody of the criminal justice system for those who refuse to show respect and seriously transgress against their neighbors.
These hybrids have as their goals group wellness and individual development, not incarceration and social control.
Someone like Mrs. Marlene Marten would be an object of love and service, not the loathing and sanction she unjustly suffered.
When they arrest Black grandmothers, we really ought to be providing real security for our community!
The author has work on any search engine and SWS Results!, his company, offers events and organizations advice and supervision for greater safety and success.
Payment can be remitted via PayPal at firstname.lastname@example.org or the address below:
Nard Enzi, Owner, SWS Results!, PO BOX 11042, Savannah, GA. 31412 (912) 412-3806 and swsresults.com.
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Metrics will be available once more articles are published.
Sirtuin 1: A Dilemma in TransplantationRead the full article
Journal of Transplantation publishes research related to heart, lung, kidney, liver, pancreas and stem cell transplantation as well as focusing on the histocompatibility, related side effects and complications of those transplantations.
Journal of Transplantation maintains an Editorial Board of practicing researchers from around the world, to ensure manuscripts are handled by editors who are experts in the field of study.
Latest ArticlesMore articles
Pretransplant Donor-Specific Anti-HLA Antibodies and the Risk for Rejection-Related Graft Failure of Kidney Allografts
Background. The presence of donor-specific antibodies (DSAs) against HLA before kidney transplantation has been variably associated with decreased long-term graft survival. Data on the relation of pretransplant DSA with rejection and cause of graft failure in recipients of donor kidneys are scarce. Methods. Patients transplanted between 1995 and 2005 were included and followed until 2016. Donor-specific antibodies before transplantation were determined retrospectively. For cause, renal transplant biopsies were reviewed. Results. Pretransplant DSAs were found in 160 cases on a total of 734 transplantations (21.8%). In 80.5% of graft failures, a diagnostic renal biopsy was performed. The presence of pretransplant DSA (DSApos) increased the risk of graft failure within the first 3 months after transplantation (5.2% vs. 9.4%) because of rejection with intragraft thrombosis (). One year after transplantation, DSApos recipients had an increased hazard for antibody-mediated rejection at 10 years (9% DSAneg vs. 15% DSApos, ) with significant decreased graft survival at 10 years (79% DSAneg vs. 69% DSApos, ). This could largely contribute to an increased graft loss because of antibody-mediated rejection in the DSApos group. The incidence and graft loss because of T cell-mediated rejection was not affected by the presence of pretransplant DSA. Conclusions. Pretransplant DSAs are a risk factor for early graft loss and increase the incidence for humoral rejection and graft loss but do not affect the risk for T cell-mediated rejection.
Type of Preservation Solution, UW or HTK, Has an Impact on the Incidence of Biliary Stricture following Liver Transplantation: A Retrospective Study
Organ preservation plays a crucial role in the outcome following solid organ transplantation. The aim of this study was to perform a retrospective outcome analysis following liver transplantation using histidine tryptophan ketoglutarate (HTK) or the University of Wisconsin (UW) solutions for liver graft preservation. We retrospectively reviewed data on adult patients who were liver-transplanted at Karolinska University Hospital between 2007 and 2015. There was evaluation of donor and recipient characteristics, pre- and post-transplant blood chemistry tests, biliary and vascular complications, graft dysfunction and nonfunction, and patient and graft survivals. A total of 433 patients were included in the analyses, with 230 and 203 patients having received livers preserved with HTK and UW, respectively. Mean follow-up was 45 ± 29 months for the HTK group and 42.4 ± 26 for the UW group. There was no difference between the two groups either in terms of patient and graft survival, or of results of postoperative blood chemistry, or incidence of arterial complications, early allograft dysfunction, or primary graft nonfunction. However, the incidence of biliary stricture was higher in the UW group (22.7%) versus the HTK group (13.5%; ). Use of UW and HTK preservation solution in liver transplantation has no impact on patient and graft survival. However, use of HTK solution results in a lower incidence of posttransplant biliary stricture.
Endothelial Glycocalyx Shedding Occurs during Ex Vivo Lung Perfusion: A Pilot Study
Background. Damage to the endothelium has been established as a key pathological process in lung transplantation and ex vivo lung perfusion (EVLP), a new technology that provides a platform for the assessment of injured donor lungs. Damage to the lung endothelial glycocalyx, a structure that lines the endothelium and is integral to vascular barrier function, has been associated with lung dysfunction. We hypothesised that endothelial glycocalyx shedding occurs during EVLP and aimed to establish a porcine model to investigate the mechanism underlying glycocalyx breakdown during EVLP. Methods. Concentrations of endothelial glycocalyx breakdown products, syndecan-1, hyaluronan, heparan sulphate, and CD44, were measured using the ELISA and matrix metalloproteinase (MMP) activity by zymography in the perfusate of both human (n = 9) and porcine (n = 4) lungs undergoing EVLP. Porcine lungs underwent prolonged EVLP (up to 12 hours) with perfusion and ventilation parameters recorded hourly. Results. During human EVLP, endothelial glycocalyx breakdown products in the perfusate increased over time. Increasing MMP-2 activity over time was positively correlated with levels of syndecan-1 (r = 0.886; ) and hyaluronan (r = 0.943; ). In the porcine EVLP model, hyaluronan was the only glycocalyx product detectable during EVLP (1 hr: 19 (13–84) vs 12 hr: 143 (109–264) ng/ml; ). Porcine hyaluronan was associated with MMP-9 activity (r = 0.83; ) and also with dynamic compliance (r = 0.57; ). Conclusion. Endothelial glycocalyx products accumulate during both porcine and human EVLP, and this accumulation parallels an accumulation of matrix-degrading enzyme activity. Preliminary evidence in our porcine EVLP model suggests that shedding may be related to organ function, thus warranting additional study.
Clinical Significance of Renal Allograft Protocol Biopsies: A Single Tertiary Center Experience in Malaysia
Background. The role of protocol renal allograft biopsy in kidney transplantation is controversial due to the concern with procedural-related complications; however, its role is slowly evolving. Recent evidence suggests that protocol biopsy is useful in detecting subclinical renal pathology. Early recognition and treatment of renal pathologies can improve long-term outcomes of renal allografts. Methodology. A total of 362 renal allograft protocol biopsies were performed in adult recipients of kidney transplantation between 2012 and 2017. After excluding those with poor quality or those performed with a baseline serum creatinine level >200 umol/L, we analyzed 334 (92.3%) biopsies. Histology reports were reviewed and categorized into histoimmunological and nonimmunological changes. The immunological changes were subcategorized into the following: (1) no acute rejection (NR), (2) borderline changes (BC), and (3) subclinical rejection (SCR). Nonimmunological changes were subcategorized into the following: (1) chronicity including interstitial fibrosis/tubular atrophy (IFTA), chronic T-cell-mediated rejection (TCMR), unspecified chronic lesions, and arterionephrosclerosis, (2) de novo glomerulopathy/recurrence of primary disease (RP), and (3) other clinically unsuspected lesions (acute pyelonephritis, calcineurin inhibitors toxicity, postinfective glomerulonephritis, and BK virus nephropathy). Risk factors associated with SCR were assessed. Results. For the histoimmunological changes, 161 (48.2%) showed NR, 145 (43.4%) were BC, and 28 (8.4%) were SCR. These clinical events were more pronounced for the first 5 years; our data showed BC accounted for 59 (36.4%), 64 (54.2%), and 22 (40.7%) biopsies within <1 year, 1-5 years, and > 5 years, respectively (p = 0.011). Meanwhile, the incidence for SCR was 6 (3.7%) biopsies in <1 year, 18 (15.3%) in 1-5 years, and 4 (7.4%) in >5 years after transplantation (p=0.003). For the nonimmunological changes, chronicity, de novo glomerulopathy/RP, and other clinically unsuspected lesions were seen in 40 (12%), 10 (3%), and 12 (3.6%) biopsies, respectively. Living-related donor recipients were associated with decreased SCR (p=0.007). Conclusions. Despite having a stable renal function, our transplant recipients had a significant number of subclinical rejection on renal allograft biopsies.
A Prognostic Tool for Individualized Prediction of Graft Failure Risk within Ten Years after Kidney Transplantation
Identification of patients at risk of kidney graft loss relies on early individual prediction of graft failure. Data from 616 kidney transplant recipients with a follow-up of at least one year were retrospectively studied. A joint latent class model investigating the impact of serum creatinine (Scr) time-trajectories and onset of de novo donor-specific anti-HLA antibody (dnDSA) on graft survival was developed. The capacity of the model to calculate individual predicted probabilities of graft failure over time was evaluated in 80 independent patients. The model classified the patients in three latent classes with significantly different Scr time profiles and different graft survivals. Donor age contributed to explaining latent class membership. In addition to the SCr classes, the other variables retained in the survival model were proteinuria measured one-year after transplantation (HR=2.4, p=0.01), pretransplant non-donor-specific antibodies (HR=3.3, p<0.001), and dnDSA in patient who experienced acute rejection (HR=15.9, p=0.02). In the validation dataset, individual predictions of graft failure risk provided good predictive performances (sensitivity, specificity, and overall accuracy of graft failure prediction at ten years were 77.7%, 95.8%, and 85%, resp.) for the 60 patients who had not developed dnDSA. For patients with dnDSA individual risk of graft failure was not predicted with a so good performance.
Renal Dysfunction after Living-Donor Liver Transplantation: Experience with 500 Cases
Introduction. The possible risk factors for chronic kidney disease in transplant recipients have not been thoroughly investigated after living-donor liver transplantation. Material and Methods. A retrospective cohort study of consecutive adults who underwent living-donor liver transplantation between May 2004 and October 2016, in a single center, was conducted. Kidney function was investigated successively for all the patients throughout the study period, with 12 months being the shortest follow-up. Postoperative renal dysfunction was defined in accordance with the Chronic Kidney Disease Epidemiology Collaboration criteria. The patients’ demographic data, preoperative and intraoperative parameters, and outcomes were recorded. A calcineurin inhibitor-based immunosuppressive regimen, either tacrolimus or cyclosporine, was used in all the patients. Results. Of the 413 patients included in the study, 33 (8%) who survived for ≥1 year experienced chronic kidney disease 1 year after living-donor liver transplantation. Twenty-seven variables were studied to compare between the patients with normal kidney functions and those who developed chronic kidney disease 1 year after living-donor liver transplantation. Univariate regression analysis for predicting the likelihood of chronic kidney disease at 1 year revealed that the following 4 variables were significant: operative time, P < 0.0005; intraoperative blood loss, P < 0.0005; preoperative renal impairment, P = 0.001; and graft-to-recipient weight ratio (as a negative predictor), P < 0.0005. In the multivariate regression analysis, only 2 variables remained as independent predictors of chronic kidney disease at 1 year, namely, operative time with a cutoff value of ≥714 minutes and graft-to-recipient weight ratio as a negative predictor with a cutoff value of <0.91. Conclusion. In this study, prolonged operative time and small graft-to-recipient weight ratio were independent predictors of chronic kidney disease at 1 year after living-donor liver transplantation.
Metrics will be available once more articles are published.

domain: medical


January 17, 2017 - March 31, 2017
The City is currently accepting applications for three Budget Committee vacancies for Fiscal Year 2019.
March 18, 2017, 11:00 AM - 1:00 PM @ Sheldon Branch Library
Drop in to watch Donna Crispin create baskets.
March 18, 2017, 1:00 PM - 2:00 PM @ Springfield Public Library
Drop in to talk about the NEA Big Read novel.
March 18, 2017, 2:00 PM - 4:00 PM @ Downtown Library
Learn to make traditional Chinese dumplings with UO Confucius Institute.
March 18, 2017, 10:15 AM - 10:45 AM @ Downtown Library
This week: Samuel Becerra.
March 18, 2017, 10:15 AM - 11:15 AM @ Sheldon Branch Library
Sign up to build, play, and explore.
March 18, 2017, 11:15 AM - 11:45 AM @ Bethel Branch Library
Una hora de cuentos en español.
March 18, 2017, 2:00 PM - 3:30 PM @ Downtown Library
Kids: pre-reg. to read aloud with dogs.
March 18, 2017, 2:00 PM - 3:00 PM @ Bethel Branch Library
March 18, 2017, 9:00 AM - 12:00 PM @ Lone Oak Park
Want to improve safety and trails at Lone Oak Park? We need your help to get the gravel in and take the trash out of Lone Oak park on Saturday, March 18. Volunteers will spread some much needed gravel along the trail and remove trash from this future developed park to improve safety for park users.
Volunteers should come dressed to get dirty, prepared for the weather and ready to make a difference!
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text:
Tropar, Resurrectional Tone 1
Dear brothers and sisters in Christ —
Notes for the Divine Liturgy of Our Father among the Saints John Chrysostom, Archbishop of Constantinople, in parallel Ukrainian and English texts from the Добрий Пастир молитовник ∞ Good Shepherd prayer book, Ukrainian Orthodox Church of Canada (UOCC). Winnipeg, 2013.
Music arranged by the Very Reverend Archpriest Bohdan Hladio for the Eastern Eparchy of the Ukrainian Orthodox Church of Canada (UOCC) Cantoring Skills Workshop.

domain: library


text:
Assumption 2: In terms of life form, the Saltwater Crocodile and similar relatives have held the position at the absolute top of the food pyramid in the habitat of transition between land and water for longer than any other life form that emerged in biological evolution.
To examine assumption 2, it is necessary to draw mainly on the findings of the paleontological sciences on the evolution of crocodilians and relatives. Here, too, a stable verification with astonishing detail can be achieved. First, however, a clarification takes place again: the assertion that the Saltwater Crocodile itself or other modern crocodilian species have not changed over several dozen or even a hundred million years is probably not correct. However, there is, so to speak, a true core to this statement, which goes back much further and which will be at the centre of this verification.
If one first looks at the results of paleontology, which have been collected by fossils and genetic analysis in relation to the duration of the existence of today’s Saltwater Crocodile, these lie in a range of 4 – 4.5 million years . The age of the species, as well as its ancestry, is rather murky because – as with most animal species – there are not enough fossil traces for such long-term empirical surveys.
It should be noted that in the taxonomic delimitation of real “species”, narrow margins are set in the biological systematics, the most important framework of which is the isolated reproductive community and very far-reaching similarities in anatomical details. The overall assessment made by scientists assumes that the species of today’s Saltwater Crocodile developed 6 to 12 million years ago .
Assumption 2 is not only about the species itself, but also the form of life with similar relatives, and thus a previously announced, even more interesting aspect emerges, which is not limited to “only” 4.5 or even 12 million years of evolution, but covers periods of up to a quarter of a billion years into the past. To this extent, fossils can be used to identify animals whose expert reconstruction produces forms very similar to today’s Saltwater crocodile. It can therefore be assumed that similar photos to those above and to the right could have been taken, hardly distinguishable to a layman, on a journey through time that would lead so far into the past that today’s continents would not even exist.
The land surface of the planet at that time consisted mainly of the giant continent Pangaea, which had just started to drift apart slightly. In the following explanations, I will assign all such reptiles emerged in evolution which strongly resemble today’s crocodilians to the “crocodile form” (note: this is independent of the taxonomic term cocodilforms). The purpose of this simplification is not a trick, to cheat the verification. Rather, it is about the amazing phenomenon of so-called “convergence” as a very important part of evolution. It will soon become clear what this is all about.
The unbelievably long Success Story of the Crocodile Form over a Quarter of a Billion Years of Evolution
The best known of those representatives of the crocodile form, which already existed well over 200 million years ago in the geological Triassic epoch (252.2 – 201.3 million years), belonged to the Phytosauria. Their numerous species, among them those of the genus Smilosuchus (living reconstruction see picture), were no direct ancestors of any of today’s crocodiles. A relationship exists only by a common line to the Crurotarsi, which numerous reptiles also belonged to, and which had no or very few similarities to the crocodile form.
However, such phytosaurs as Smilosuchus adamenensis are also attributed by expert scientists in almost every respect as having far-reaching similarities to today’s crocodiles  . The only anatomical difference that was more striking was that the nasal openings of Smilosuchuchus and other phytosaurs were not at the tip of the snout, as in today’s crocodiles, but close to the eyes. The evolutionary purpose of this anatomy was, according to current scientific opinion, to be able to submerge the rest of the body at the surface of the water with a minimum of recognition , i.e. to remain as inconspicuous as possible.
The phytosaurs and their crocodile forms probably became extinct during the fourth great mass extinction in geological history, at the border between the Triassic and the Jurassic periods, about 201 million years ago. This event was probably caused by comet impact and volcanic eruption. Most previously existing large reptiles and, according to current expert opinion, up to 75 percent of all animal and plant species of the time did not survive this caesura. In the subsequent Jura (201.3 – 145 million years) and Cretaceous (145 – 66 million years) epochs. During the following evolution the ecological niches freed up in this way were occupied slowly, for example by the, initially, still rather small dinosaurs.
The crocodile form, on the other hand, reappeared quite shortly after the Triassic-Jura border in relation to the overall time frame. And again its evolution led to numerous semi-aquatic genera and species at the transition between land and water. It has been proven that the extensive Goniopholididae family existed from the beginning of the Jurassic period almost 200 million years ago until the late Cretaceous period. The oldest fossil evidence for this originates from the Calsoyasuchus valliceps species, and was dated at 196.5 million years . The fossil traces show that during the evolution many crocodiles sometimes tended towards a more aquatic or more land-based anatomy, but on the whole “settled” on largely the same form, what I alternatively call the “crocodile form”.
One example of a tendential deviation towards a more aquatic anatomy was the Machimosaurs (picture). They existed 160 to 130 million years ago, and probably spent most of their time in the sea, but still had legs. The largest known species, the Machimosaurus hugii, with a length of up to 12 meters, probably hunted for fish and turtles in the ocean as well as for large land animals on the shore, according to expert reconstructions, and its anatomy has far-reaching parallels with today’s Saltwater Crocodiles.
The extensive group of Pholidosauridae, whose species can be traced from the middle Jurassic to the late Cretaceous period (167.7 to 89.3 million years), moved predominantly in the anatomical centre of the crocodile form during evolution.
The largest of these, according to previous evidence, belonged to the genus Sarcosuchus (112.9 to 93.9 million years) with a body length of up to 11 meters and a weight of eight tons (picture). They lived around inland waters or brackish water zones, and probably hunted there as today’s crocodiles do. Sarcosuchians may be an example of crocodiles adapting their size during evolution, when dinosaurs on land developed increasingly large predatory forms from around the middle of the Cretaceous period.
Another suitable example are Deinosuchus, which, according to many experts, were superior to even the largest and strongest predatory dinosaurs, and perhaps even captured them as food. An empirical reconstruction of the biting power of this giant crocodile, up to 12 meters long and which lived about 70 or 80 million years ago, yielded a value of more than 100,000 N, which is far higher than that attributed to the species of the large Tyrannosaurus species , and even traces of bites on fossil bones of large predatory dinosaurs have been found to match fossil parts of Deinosuchus .
As in the Triassic period, numerous genera and species of the crocodile form existed during the 130 million year Jurassic and Cretaceous periods. Meanwhile, numerous other forms of large reptiles also appeared on the planet. Dinosaurs alone developed thousands of different species of land animals during their evolution, including small raptors and huge herbivores weighing over 80 tons. They also produced the largest known land predators, such as the well-known Tyrannosaurus Rex. In the air, the Pterosaurs were the largest animals capable of flight that probably ever existed. They, too, were carnivores: their wingspans reached well over ten meters and their weight more than half a ton. In the open ocean, other large reptiles existed at the top positions of the food pyramid, such as the species of Plesiosaurs and Mosaurs, with bodies weighing up to several tons and stretching to 20 meters long.
Almost all the large reptiles of the Jurassic and Cretaceous periods are no longer existent today. They disappeared, at the latest, during the fifth geological mass extinction about 66 million years ago, which was probably also caused by a comet impact and volcanic eruptions, and their possible remaining species did not develop back into their former positions afterwards. This also applies to all large dinosaurs. There are still the birds today which are direct descendants of dinosaurs, but they have become and remain relatively small creatures during evolution with many variations.
Only one form of the many large reptiles returned to their old position after the last geological catastrophe: Crocodiles. Most of their species probably died out 66 million years ago, and it could well be possible that the top position in the food pyramid at the transition between water and land was interrupted for some time. However, it can be stated with certainty that the crocodile form came back again in numerous genera and species, and that these showed a striking similarity to the species already existing a quarter of a billion years ago. And some still occupy their position at the top of the foodchain in the area between water and land today.
A steady Return through Convergence was more important to their long History than Survival
There is hardly anyone in paleontology who assumes that these recurring and far-reaching similarities are due to the common affiliation to the Crurotarsi branch . There are certainly some beneficial foundations in this regard for a steady return, but nearly 250 million years is an extremely long period of time, even on an evolutionary scale. Even over much shorter periods of time, biological evolution can produce many different living beings from a single parent form, whose recognizable characteristics are barely similar.
The real cause of the enormous similarity of Smilosuchus and the Saltwater Crocodile (as well as the species of the crocodile form that existed inbetween) is, also in the opinion of the expert paleontologists, “convergence”. This is about the fact that even life forms develop similar characteristics completely without relevant relationships to pure evolutionary adaptations in the same environmental conditions. Sometimes there are such strong similarities that practically unrelated species can hardly be distinguished, at least by a layman. Well-known examples are snakes and blindworms (Anguis fragilis), as well as swifts (Apus apus) and swallows (Hirundinidae).
The results of convergence sometimes extend to such precise details that it may be difficult to attribute these parallel developments to their mere adaptation to environmental conditions. On the other hand, in the reflective reconstruction of the respective developmental processes, even laypersons can quickly understand their evolutionary logic. Swifts and swallows have focused on the same food source of insects flying in the air. However, they did not only adapt to the mere snapping of the prey. Rather, through constant selection, they also aligned themselves as optimally as possible to the intersection of all the laws of nature which affect them during this activity. This ranges from such things as temperatures, thermals, humidity, gravity, centrifugal force, acceleration and everything that can be classified under the kinetics and dynamics. Since both swallows and swifts were affected by the same goal and same intersection of all the relevant laws of nature, two quite similar and small agile bodies with pointed wings emerged.
Power and Potential for Violence cannot have been the Recipe for Success of the Crocodile Form
The topic of the convergence of the “crocodile form” will be taken up later. Here, however, there are some further clarifications needed regarding frequent errors, which sometimes even reach into paleontological circles. One such error is the assumption that crocodiles were so persistent because they had such a great potential for physical violence. This is easy to refute, because the crocodile forms were demonstrably neither always defined by such physical size and extreme potential for violence as the Saltwater Crocodile or the Deinosuchus, nor were they dependent on such strong teeth as the latter examples possessed.
Since the Triassic period, many and much smaller species of the crocodile form have been found. There were large crocodiles both before and after the end of the Cretaceous period, which had a rather fragile muzzle, which did not fit at all to assumption number 1. The Ganges-Gharial, which still exists today, is up to six meters long, so it is hardly smaller than the Saltwater Crocodile and has a similar body. However, there is only one striking difference and it consists of a very narrow set of teeth, designed to catch smaller fish and ducks. The extreme potential for violence that can be seen in Saltwater Crocodiles is certainly a factor that affects their recurring position at the absolute top of the food pyramid. It cannot be, however, the most important and fundamental ingredient in their evolutionary recipe for success.
Other hypotheses about the extreme resistance of crocodiles, which are often discussed, quickly lose their substance upon closer inspection. Thus, often without knowing the overall history of the crocodile form, their stability is determined alone by the ”survival” of the violent geological and climatic faults at the end of the Cretaceous period, 66 million years ago. It is not uncommon for some supposedly decisive characteristics of crocodilians to be presented as a solution to the ”mystery” of this ”survival”, such as the fact that they were hematocryal and had a broad food spectrum.
In fact, however, there is no evidence that crocodiles survived the caesura 66 million years ago, in the sense that their species continued to exist under dark ash clouds and in icy cold temperatures. There is much to suggest that they largely disappeared. Out of the remains, which could quite likely have been small species without many similarities to the large Deinosuchus or the Saltwater Crocodile, the crocodile form came back through the evolutionary process with many species, including those at the absolute top of the food pyramid. This is – just like after the Triassic-Jurassic border – the crucial point. It must be about much more solid and fundamental factors of stability than the accidental survival of a single catastrophe.
The real mystery then lies in the questions of why this form was constantly reborn in the process of evolution, why it formed such striking similarities even over 250 million years, and why some of its species took the absolute top place in the food pyramid, at the transition between water and land again and again. If this mystery of biological evolution can be solved anywhere, there can be no better opportunity than to observe the strongest of all currently existing crocodiles. That has to be done where they themselves unfold, free and undisturbed, into their true nature.
In conclusion, it can be stated here that the proof of assumption 2 has also been provided in a stable manner. There is definitely no other proven form of life that has even come close to achieving such enormous stability at the top of the food pyramid, at the transition from water to land. There is no continuous line of corresponding species that leads from the Saltwater Crocodile, without interruption, up to 240 million years into the past. Already, however, the examples mentioned, which could be extended even further, are sufficient for the lack of any serious competition.
 Johnson, D. (2009). The Geology of Australia. Cambridge: Cambridge University Press. p. 181. ISBN 978-0-521-76741-5. Retrieved 28 July 2013.
 Willis, P. M. A. (1997). “Review of fossil crocodilians from Australasia”. Australian Journal of Zoology. 30 (3): 287–298. doi:10.7882/AZ.1997.004.
 Molnar, R. E. (1979). “Crocodylus porosus from the Pliocene Allingham formation of North Queensland. Results of the Ray E. Lemley expeditions, part 5”.Memoirs of the Queensland Museum. 19: 357–365..
 Nesbitt, SJ; Norell, MA. (2006). “Extreme convergence in the body plans of an early suchian (Archosauria) and ornithomimid dinosaurs (Theropoda)”. Proceedings of the Royal Society of London B: Biological Sciences. 273 (1590): 1045–1048. doi:10.1098/rspb.2005.3426. PMC 1560254. PMID 16600879.
 Nesbitt, S. (2007). “The anatomy of Effigia okeeffeae (Archosauria, Suchia), theropod-like convergence, and the distribution of related taxa” (PDF). Bulletin of the American Museum of Natural History. 302: 84. doi:10.1206/0003-0090(2007)302[1:taoeoa]2.0.co;2.
 Tykoski, Ronald S. et al (2002): “Calsoyasuchus valliceps, a new crocodyliform from the Early Jurassic Kayenta Formation of Arizona”. Journal of Vertebrate Paleontology. 22 (3): 593–611. doi:10.1671/0272-4634(2002)022[0593:CVANCF]2.0.CO;2
 Gregory M. Erickson, et al: Insights into the Ecology and Evolutionary Success of Crocodilians In: PLoS ONE. Bd. 7, Nr. 3, 2012, e31781. doi:10.1371/journal.pone.0031781.
 Schwimmer, David R. (2002). “The Prey of Giants”. King of the Crocodylians: The Paleobiology of Deinosuchus. Indiana University Press. pp. 167–192. ISBN 978-0

domain: biology


Dropped the wing removed some of the lower fuse that was damaged in a bad landing. Lost 50 grams in the process and the wheels which are no good at our field.
The angle of incidence remains the same as the plans. I'm hoping the lowering of the wing relative to the thrust line will reduce the nose up tendency with power.
If the wind ever stops blowing I will fly it


text:
Billed as an erotic private eye spoof, That's My Daughter! is an attempt to provide the viewer with good sex, an interesting story and a first-rate production. It's a film which recognizes that adult entertainment means more than several sex strung together with an inane story line. Like Roommates and Taboo, That's My Daughter! wants to be considered as a movie first and as a sex film second. Unlike these films, however, it falls far short of this goal.
The cast includes some of the best performers working in adult films, and introduces a promising new actress, Karen Sweet, as the daughter. Lisa DeLeeuw will disappoint her legion of loyal fans because even though she gets star billing she makes only a brief cameo appearance, turns in an adequate but undistinguished sex scene and then is no longer seen. Arcadia Lake, a personal favorite who has been out of the business for a while, makes a rare screen appearance opposite her real life husband Eric Edwards. The bulk of the acting chores are handled by veterans Eric Edwards, John Leslie, Sharon Mitchell, Herschel Savage, and an unknown woman narrator with a passable French accent. So far so good. But, the film's real weakness is that it depends on a plot that, while superficially interesting, never quite lives up to the viewer's expectations.
The film's narrator, a French madam, is contracted by a wealthy client who is seeking his long-lost daughter, recently discovered as a porn actress in an obscure film. The madam refers her client to the offbeat detective team of Angel (Sharon Mitchell) and Johnny (Eric Edwards). Angel, a tough cookie, is constantly turning down the advances of boss Johnny.
Meanwhile, long-lost Stephanie (Karen Sweet) is bouncing from man to man, thoroughly enjoying her life as a hooker. But the gig is soon up, as Johnny and Angel burst in on Stephanie and a client. A multitude of plot-lines are unraveled: father and daughter run off to renew their relationship; Johnny gets Angel; and the French madam who narrated the film starts another story as the film ends.
Somewhere between an interesting story line and the end product something went wrong. The biggest single flaw in the film is the script; it never puts all the story elements together in a satisfying way. The film claims to be a madcap detective spoof implying that there is more than a little humor and hijinks. There is no humor in this film; nothing is played for laughs. There is a lot of silliness in this film – stupid things that aren't funny.
But what about the sex, you ask? Tell us about the good stuff. Well, there's not much to tell. Although a fair amount of sex scenes are good, it is because of the performers. The problem with this film's sex is that it's pretty standard fare – nothing out of the ordinary and no particularly steamy scenes.
If you're looking for an entertaining, fun-filled, sexy detective story as this film purports to be, you'll be disappointed. If you're looking for a sex film with good production, familiar faces, and an okay story, then That's My Daughter! is worth a try.

domain: entertainment