Prosecutors in these seven U.S. courtrooms want ‘El Chapo’
The expected extradition of Mexican drug lord and prison escape artist Joaquin “El Chapo” Guzman to the United States may take months, but it already has caused a tug of war among federal prosecutors in the key jurisdictions that want to put him on trial — San Diego, Chicago and New York City.
U.S. attorneys in seven jurisdictions have charged Guzman, who was recaptured Friday in Mexico, with organized crime, murder and drug trafficking in his role as head of the Sinaloa cartel.
Under Guzman, prosecutors say, the cartel dramatically increased the flow of illegal narcotics into the U.S. by partnering with Colombian producers. The network ultimately became the largest bulk smuggler of marijuana, cocaine and heroin to the U.S. and Europe.
Indictments against Guzman are pending in the Southern District of California, the Northern District of Illinois, the Eastern District of New York, the Western District of Texas based in El Paso, the Southern District of New York in Manhattan, the U.S. District of New Hampshire and the Southern District of Florida in Miami.
Prosecutors in San Diego brought the first federal charges against Guzman in 1996 in a push to dismantle a cocaine ring that ran from Southern California to the East Coast. The Justice Department filed an extradition request for him last summer based on the San Diego charges shortly before he made global headlines by escaping from a high-security prison near Mexico City.
In Chicago, Guzman and 10 others were indicted by a federal grand jury in 2008 on charges of shipping tons of drugs to the Midwest and threatening to behead the agent in charge of the local Drug Enforcement Administration office. Authorities labeled Guzman “Public Enemy No. 1,” a moniker previously reserved for Prohibition-era gangster Al Capone.
The Chicago case has the best chance to persuade Mexican authorities to extradite Guzman to the U.S., because prosecutors in Chicago have more “live witnesses” who can take the stand and testify against him, according to Carl Pike, a former high-level official in the DEA.
The son of one of Guzman’s top lieutenants is in custody in Chicago and is cooperating with authorities. Vicente Zambada-Niebla pleaded guilty to intent to distribute multiple tons of cocaine and heroin in 2013, and his reported knowledge of Guzman’s role could make a prosecution there more likely.
The Office of International Affairs in the Criminal Division of the Justice Department manages extradition requests from federal prosecutors. When there are competing requests, as with Guzman, officials there recommend the jurisdiction with the strongest case.
“They will pick the ... case with the highest chance of success,” said Pike, who recently retired after 27 years as a DEA agent.
But where Guzman stands trial may ultimately be decided by Atty. Gen. Loretta Lynch.
Lynch previously served as U.S. attorney in Brooklyn and may want her former office, which has significant experience in winning convictions in complex, high-profile criminal cases, to take the case.
Federal prosecutors in Brooklyn filed charges against Guzman in 2009 and recently combined them with another case in Florida.
Officials in Mexico say they are finally willing to extradite Guzman, after refusing to do so following his previous arrests. But his lawyers will strenuously fight his transfer, and the legal process could take up to a year, officials said.
Joaquin “El Chapo” Guzman, one of the world’s most powerful drug kingpins, gained folklore status during his decade-plus on the lam, evading authorities thanks to his skill at building secret tunnels from his assorted mountain hideouts, urban safe h
THE EXTRADITION PROCESS
Jose Manuel Marino, the director of international processes at Mexico’s attorney general’s office, said Monday that the “extradition process has begun” although he added that Mexican law doesn’t allow for immediate transfer of a prisoner to another country.
“Right now, our legislation doesn’t allow for that,” Marino said in an interview on Televisa’s “Primero Noticias.” “We have to abide by our international commitments and the extradition law. The treaty, the law and the penal code carry specific terms for the extradition process.”
Juan Pablo Badillo, who represents Guzman, said his legal team already has filed six legal appeals in an effort to delay or obstruct the extradition process. Legal experts said the tactic is unlikely to prevent extradition, however.
Badillo argued that Guzman should be tried in a Mexican court, and serve any sentence in a Mexican prison, before he can be extradited.
The lawyer said he had not been given an opportunity to speak to Guzman since his capture in the coastal city of Los Mochis after a months-long manhunt that culminated in a gun battle near the house where he had been hiding.
Mexican authorities had received a tip from a neighbor about loud noise, more people than usual and what looked like a large armory moving in and out of the property, Pike said in a telephone interview.
Guzman returning to his hometown was like “the rabbit going back to the briar patch,” he said.
Mexican authorities and DEA agents tracking Guzman knew about his ties to the property, but it had been quiet for several years, Pike said.
“Then the phone call comes in,” he said. “There was no activity and now there is a ton of activity. The true catalyst was a neighbor’s call.”
Federal prosecutors had repeatedly sought to extradite Guzman, and the Justice Department filed another request based on the San Diego charges 16 days before he escaped last July. Exiting his cell at the Altiplano prison through a hole in the shower stall floor, Guzman descended into a tunnel his organization had built and rode a motorcycle to freedom.
Guzman has been returned to the prison since his recapture, and Mexican authorities insist he will not escape again.
If he is transferred to the U.S., Guzman probably would be incarcerated with other notorious criminals in the federal “Supermax” jail in Florence, Colo., while he awaits trial.
Keeping Guzman behind bars is unlikely to slow drug trafficking by the Sinaloa cartel, said Jonathan Duecker, a DEA agent from 1998 to 2003, who recently studied transnational criminal organizations as a staff member for the House Homeland Security Committee.
“There was no discernible impact when he was in prison” on the flow of drugs or the amount of cash moving from the U.S. to Mexico, Duecker said Monday.
“Just because he is locked up, doesn’t mean we will see a degradation in their operations,” he added. “We may see an increase in violence across the border as other cartels try to assert their market foothold within the U.S.”
Times staff writer Bennett reported from Washington and special correspondent Bonello from Mexico City.
Start your day right
Sign up for Essential California for the L.A. Times biggest news, features and recommendations in your inbox six days a week.
You may occasionally receive promotional content from the Los Angeles Times.


When you think of a fast red car, you would be forgiven if a Ferrari comes to mind. However, back in the early 20th century Maserati were the red cars to beat. Founded by the Maserati brothers in 1914, the name is full of racing pedigree. The Maserati 250F is one of the brands most celebrated racing cars.
The Maserati 250F made its debut in 1954. The streamline cigar shaped body initially housed a 220-hp 2.5-liter straight-six engine that first roared into life at the Argentine Grand Prix. Piloted by Jaun Manuel Fangio, the 250F claimed victory on its first outing. Fangio took the top step again with his Maserati before moving to the newly formed Mercedes-Benz team.
Another 250F pilot of note was Sterling Moss who raced his privately owned Maserati throughout 1954.
The car was developed for the 1955 season featuring a new 5-speed gearbox, cutting-edge Dunlop disc brakes and a 20-hp increase thanks to fuel injection.
1956 saw the introduction of the thoroughly revised 250F T2. A lighter but stiffer construction improved handling whilst a 315-hp V12 replaced the straight-six. Sterling Moss, now in a works car, claimed victory in Monaco and Italy.
Fangio got back behind the wheel of a Maserati 250F for ’57 in spectacular fashion. It would become the year this racing car is now most famed for. Four strong wins included one of motorsport’s most iconic races. At the Nürburgring, Fangio made up a 48-second deficit over 22 laps, breaking the lap record not once, but ten times in the process. It was an incredible victory.
By 1958, front-engine racing cars were consistently being outperformed by their more advanced mid-engine rivals. That said, the 250F continued to be used by private teams for a few more years.
The Maserati 250F became an icon with Sterling Moss even remarked that it was the best front-engine Grand Prix car he ever raced.


text:
|Availability:||In stock (1)|
1883. Framed & Under Glass, Paper Flyer for the Knight of Pythias Grand Ball in the Junction House in Freeville, NY. This is dated for December 25, 1883. The event was being presented by the Freeville Lodge No. 201, K. of P. with music to be presented by Arthur Love's Full Orchestra. The prompter was Jay Shaver. This flyer was printed by The Dryden Herald Print. A small hole in the top left corner, but otherwise in amazing condition. See photos.

domain: library


text:
London black cab trials cashless payments using mobile phone app
Passengers can transfer the fare from their phones
Monday 14 July 2014
The late night quest for a cash point could soon be a thing of the past for cab passengers as a London cabbie trials mobile phone payments.
Ian Cable is using Barclay’s Pingit app for cashless payments for five days until Friday.
It allows the fare on the meter to be transferred between bank accounts within 30 seconds.
Mr Cable, who has been a London black cab driver for 23 years, said: “I am always up for trying new technology to help make mine and my passengers' lives easier.”
He was also the first cabbie to accept chip and pin cards in 2004.
“It means I have more time on the road to earn money - rather than stopping off at the bank to pay in my earnings or pulling up at ATMs for passengers with the risk of getting a hefty parking fine," he added.
As contactless payment cards become more popular, the next shift predicted is towards mobile payments.
The Centre for Economic and Business Research predicts that by 2020, 20 million adults will use their mobiles to pay for goods and services.
Darren Foulds, the director of Barclays Mobile and Pingit, said: “We are always keen to support new ways to make people’s lives easier.
“This trial really demonstrates the huge potential for mobile payments as they gain more widespread use.”
The app, which can be used by customers of any bank, works by using QR codes to gain information needed for a transaction.
Since it launched in February 2012, Barclays Pingit has been downloaded 3 million times and used to transfer £540 million.
Life & Style blogs
Surgeon backs 'good death' plans - and reveals his own
Britain's kitchens so filthy that they present a health risk, says new research
NHS hit by stealth cuts of £2bn as tariffs received for medical procedures are reduced
How to survive a social-media mauling, by the tough women of Twitter
KickassTorrents down: new Isle of Man domain taken offline just hours after launch
General Election 2015: Chuka Umunna on the benefits of immigration, humility – and his leader Ed Miliband
The sickening truth about food banks that the Tories don't want you to know
Migrant boat disaster: Ukip candidate mocks victims in sickening Twitter post
Nigel Farage wants the BBC to stop making programmes like Doctor Who, Strictly Come Dancing, and Top Gear
Global warming: Scientists say temperatures could rise by 6C by 2100 and call for action ahead of UN meeting in Paris
General Election 2015: Britain would become a 'communist dictatorship' under Ed Miliband and Nicola Sturgeon, claims wife of Michael Gove
- 1 I've been called an abusive and dangerous parent, when all I did was listen to my transgender child
- 2 Smartphones are making children borderline autistic, says psychiatrist
- 3 Why this father didn’t hide his daughter’s heroin overdose in her obituary
- 4 Company breaks open Apple Watch to discover what it says is 'planned obsolescence'
- 5 Teaching profession headed for crisis as numbers continue to drop and working lives become 'unbearable'
iJobs Gadgets & Tech
£70000 - £90000 per annum + bonus + car allowance + benefits: Ashdown Group: H...
£28000 - £32000 per annum + Excellent benefits: Ashdown Group: Application Sup...
£28000 - £32000 per annum + Excellent benefits: Ashdown Group: Systems Analyst...
£40000 - £48000 per annum + bonus and benefits: Ashdown Group: European Recrui...

domain: news


text:
Poems to Perform
Below are some brilliant videos of famous children's poets reading their work aloud. There is also a selection of poems for you to try and read aloud and perform for your friends and family. Poetry isn't written to sit on the page, but to be acted on the stage!
Why not explore the Children's Poetry Archive. Here you can listen to poems, read poems, watch interviews with poets and learn so much more!
Watch poets recite their work for your enjoyment and entertainment below...
Below: To celebrate International Women's Day, we created our very own Book of Wonderful Women.
Here are the pages all about amazing Mancunian... Emmeline Pankhurst!

domain: entertainment


text:
How can i convert Babylon glossaries (*.BGL) to a database table (mySQL) ?
I don't know if there are any "easy" ways per say to do it, but two ways come to mind depending on what resources you have.
Export the BGL data directly to a CSV and then set up your database structure within MySQL and import the CSV.
Export the BGL data to MS Excel and then from there you there are multiple formats that you can export to that are importable by MySQL.
There are also several paid solutions that are out there that you can purchase to make the transition a little easier, but I don't know of any that are free, and I can't speak to the quality of any of them.
You can use PyGlossary
Tested and working.
Description of PyGlossay:
Working on glossarys (dictionary databases) using python. Including editing glossarys and converting theme between many formats such as: Tabfile StarDict format xFarDic format "Babylon Builder" source format Omnidic format and etc.


- Rush Limbaugh is reporting fake robocalls in Massachusetts over the last couple of days. One posed as a conservative group urging a vote for Brown, but obviously designed to step on the sensibilities of liberal Massachusetts voters. (In other words, it was a dishonest attempt to motivate votes for Coakley.) A second robocall urged a vote for Coakley, claiming that pro-life voters in Massachusetts oppose Brown (they don't).
- A Boston Globe editorial repeated the John Kerry smear of yesterday, i.e. that "Brown supporters are attempting to suppress the Coakley vote by bullying." This is, of course, complete nonsense. However, this big lie no doubt offers some comfort to Coakley supporters, who want to believe that a defeat can only come about by Republican dirty tricks. If they do lose, they will have this excuse to fall back on and use it to motivate their base.
- A pro-Coakley group was seen handing out blank absentee ballots in Spanish this morning, while offering instructions on how to mark Coakley's name. The deadline for submission of absentee ballots ended on January 15.
Well, as a wintry election day dawns in Massachusetts, I'll believe it when I see it. If all but one of those polls are right, Scott Brown now has a lead well beyond the margin of error. But, as that Boston Globe "Dead Heat!" headline suggests, it's not necessarily beyond the margin of Acorn, the margin of lawyer, and the margin of Franken-style recounts. On the other hand, if you're minded to (as MSNBC's electokleptomaniac Ed Schultz recommends) steal the vote, you don't really want to have to steal it big, on a Mugabe-esque scale.If Brown wins, then, the Dems are expected to use legal challenges to the election to either steal the election for Coakley, or at least delay seating Brown for as long as possible. The latter tactic will enable the Dems to vote in Obamacare before they lose their supermajority of 60 votes; when Brown is finally sworn in, it will be too late to stop nationalized health care.
The way to put these fears to rest, however, is to elect Brown with a solid majority of the votes. Cheating is much more difficult in the face of a convincing win.


text:
Bishop Denis Nulty
Bishop Denis Nulty and members of the Diocesan Ploughing Steering Group will gather on the site of the National Ploughing Championships at Ballintrane, near Fenagh, Carlow to launch the Kildare and Leighlin Diocesan Stand on August 15 at 3pm.
Bishop Denis is delighted to welcome the Ploughing Championships back to the diocese and is looking forward to hosting the Diocesan Stand.
Subscribe or register today to discover more from DonegalLive.ie
Buy the e-paper of the Donegal Democrat, Donegal People's Press, Donegal Post and Inish Times here for instant access to Donegal's premier news titles.
Keep up with the latest news from Donegal with our daily newsletter featuring the most important stories of the day delivered to your inbox every evening at 5pm.

domain: hobby


text:
As markets shudder with the political aftershocks of Britain's June 23 decision to leave the EU, worries are growing in Italy and the rest of the European Union about the health of the Italian banking sector.
The symptoms of a pending financial crisis are evident: Share prices in Italian banks, already sharply down since the start of the year, plummeted after the Brexit vote, and the country's lenders have 360 billion euros (400 billion dollars) of bad loans on their books - roughly one-third of the eurozone total.
Now, supervisors at the European Central Bank (ECB) are piling the pressure on the Italian lender with the biggest bad-loan problem, the Siena-based Monte dei Paschi di Siena (MPS).
The officials have urged MPS to slash its load of non-performing loans, worth almost 50 billion dollars in gross terms, by 25 per cent within two years.
A reduction of this magnitude can only succeed if MPS, considered the world's oldest bank with its launch in 1472, sells off the loans at major discounts, incurring severe losses. MPS lacks the necessary reserves for this, despite several capital increases and two state bailouts since the 2008 financial crisis.
Worries are also growing at Italy's largest bank, Unicredit, about new gaps in its books, and the lender's global status means revelations connected to the discrepancies could send shock waves around the world.
Some experts are warning that the crisis could spread to all of Europe. "The whole banking market is under pressure," Lorenzo Bini Smaghi, the Italian-born chairman of the board at French bank Societe Generale, told Bloomberg Television on Wednesday.
"Italy could pose a greater danger to the eurozone than Brexit," adds Neil Wilson of the trading firm ETX Capital.
But the European Commission, under pressure from Germany, is reluctant to let Italy proceed with public rescues.
In the wake of the 2008 financial crisis, when governments paid hundreds of billions of euros to rescue banks, Brussels adopted new rules aiming to put the onus of bailouts on shareholders and creditors, rather than tax payers.
Italy wants an escape clause from these so-called bail-in rules, arguing that imposing losses on investors, at a time when Italian bank sector shares have plunged in value, would further scare markets and increase the risk of bank runs.
So it is no wonder that Prime Minister Matteo Renzi is under huge pressure, both at home and abroad.
"Italian savers and account holders will not have any problems, and that for me is the priority," Renzi said at a press conference in Rome on Wednesday, trying to reassure the public and shift the attention on banking problems elsewhere in Europe.
"The real issue in European finance is not Italian non-performing loans, but rather the derivatives of other banks," he argued, in what was seen as pointing a finger at Deutsche Bank, as the German lender is highly exposed to the risky financial products.
"If the issue about Italian non-performing loans, which can be solved and is being solved, [...] is worth one, the issue of derivatives at other banks, at big banks, is worth one hundred. This is the ratio: one to one hundred," Renzi said.
Morgan Stanley analyst Alvaro Serrano believes that a way out for Italy could come on July 29, when the European Banking Authority publishes stress test results. An exception to EU bail-in rules provides for the use of state money to plug capital gaps unveiled by those tests.
Recent press reports suggested that Renzi was considering a 40-billion-euro package for the banks. His country, however, has to be careful with its spending, as it is the eurozone nation the highest ratio of debt to gross domestic product after Greece.
Italian banks have been major financiers of the government and hold significant chunks of public debt. These huge portfolios of state bonds on the banks' balance sheets are part of the reason why lenders have postponed a cleanup of their holdings.
Unlike conventional loans, state sovereign bonds do not have to be backed up with a bank's own capital. This is a factor which serves to lower any incentive for banks to boost their net worth. The Bundesbank has called for a rule change, but Italy has opposed it.
Renzi is also under political pressure as he considers the banking crisis.
If ordinary Italian savers were to suffer costs related to the bank bailouts, his popularity ratings would likely plummet. That's an unsavory option for the premier, who has staked his political future on the outcome of an October referendum on constitutional reform.
Renzi has promised to resign if he loses the vote. That would mark a return to political uncertainty that could domino with effects on the Italian economy and banking sector - not to mention the rest of Europe.
A 'no' to constitutional reforms in the referendum would usher in "political chaos" and a recession, business lobby Confindustria said on July 1. A day later, Citibank called the Italian vote "probably the single biggest risk on the European political landscape this year."

domain: finance


text:
Africa is the world’s second-fastest growing economic region, yet United States engagement with the continent is lagging. There’s an opportunity to change that.
The White House has invited some 50 African heads of state to Washington, DC, this week, presenting a historic opportunity to deepen US ties to the continent. But it would be a mistake to assume that the benefits of the US–Africa Leaders Summit will flow primarily to Africa. There is huge economic potential for the United States, too.
Africa is transforming from a continent in need of assistance to a continent of opportunity. Its economic growth is today second only to the East Asia region, which includes China,1 and Africa was home to 8 of the world’s 15 fastest-growing economies between 2000 and 2013. Indeed, the continent’s GDP of more than $2 trillion in 2013 is now larger than India’s.
Investors around the world have taken notice. Private-capital flows to Africa totaled $545 billion from 2003 to 2012, surpassing remittances and official aid. Yet the United States lags well behind Europe, BRIC,2 and the Middle East in terms of the amount of foreign-direct investment (FDI) it sends to Africa. Moreover, the US share of African trade stands at only 4 percent.
This may be a missed opportunity. Africa offers a higher rate of return on FDI than most emerging economies—in sharp contrast to returns that foreign investors earned 20 years ago. But to date, economic engagement between the United States and Africa has been limited relative to its potential, and much smaller than Europe’s and Asia’s economic engagement with Africa.
The rate of return on foreign direct investment in Africa is higher than in most emerging markets.
AUTHORS: Acha Leke is a director in McKinsey’s Johannesburg office; Susan Lund is a partner with the McKinsey Global Institute (MGI) and is based in the Washington, DC, office; James Manyika is a director of MGI and is based in the San Francisco office; Sree Ramaswamy is a senior fellow with MGI and is based in the Washington, DC, office.
The authors wish to acknowledge the contribution of Lohini Moodley and Safroadu Yeboah-Amankwah. This article draws on their work in the McKinsey Global Institute report “Lions go digital: The Internet’s transformative potential in Africa.”


text:
The soil technology company has joined with the MLB, the Arizona Diamondbacks and other local companies, to renovate the Boys and Girls Club of Metropolitan Phoenix.
Stabilizer Solutions, Inc. donates All-Star Baseball Field to Phoenix-area Boys & Girls Club
As Phoenix gears up for the Major League Baseball (MLB) All-Star game, the future pros of America are being given the opportunity to play on the same field as their heroes. In one of its largest renovations to date, Stabilizer Solutions, Inc. a Phoenix-based soil technology company has joined with the MLB, the Arizona Diamondbacks and other local companies, to renovate the Boys and Girls Club of Metropolitan Phoenix located at 548 W Southern Ave. A groundbreaking ceremony will be held on July 11, 2011 to dedicate the park; details are listed below. Diamondbacks, Major League Baseball, and Boys and Girls Club representatives will be in attendance.
Stabilizer Solutions donated nearly 70 tons of its Stabilizer® Pro-Red Infield Mix to help the field maintain optimal moisture levels, even during Arizona’s brutal summers. The product has been used on each of the “Diamondsback” charity field renovations to date. Stabilizer®, the original natural soil binder, is an organic, locally produced product that can also be found just blocks away on Chase Field.
“We specifically chose to donate our Stabilizer Pro-Red Infield Mix to this project because it is durable and can withstand the wear and tear of many summers of play,” said Jon Hubbs, president of Stabilizer Solutions, Inc. “Being asked to participate in this renovation project was a real honor for us and we’re hoping that this field produces many future All-Stars.”


text:
The health care of 100,000 poor women in Maryland will be jeopardized if President Bush delivers on a promise to veto legislation overturning "gag rule" restrictions on family planning clinics supported by federal funds, Baltimore medical experts said today.
The veto, expected this week, "amounts very simply to censorship within the doctor's office," according to Dr. David A. Nagey, director of the division of maternal-fetal medicine at the University of Maryland School of Medicine.
If allowed to go into effect, the gag regulations would make it illegal for health professionals in public and private clinics receiving federal funds to provide any information about terminating a pregnancy.
Even if a patient asks about abortion -- and even if continuing a pregnancy would endanger her health -- clinic staff would not be allowed to answer her questions or refer her to someone who would, Nagey said.
This would place health care providers in these clinics in the position of "a Titanic steward who had to remain silent concerning the whereabouts of life jackets and lifeboats," he said.
The gag rule is was promulgated by the U.S. Department of Health and Human Services. Congress passed legislation overturning the rule, but Bush has threatened to veto it.
Nagey, flanked by a group of doctors and nurses from the University of Maryland and Johns Hopkins University, independent social workers and others, made his comments at a news conference today at the People's Community Health Center at 3028 Greenmount Ave.
"The real issue here is not abortion," Nagey said. "[Federal] funds have never been used for abortions. In fact, each year [federal] funds help prevent 1.2 million unintended pregnancies nationwide and over 1,200 unwanted Maryland pregnancies," Nagey said.
The purpose of the conference was to decry Bush's promised action and to "send a strong message" to the Maryland congressional delegation to overturn the veto, he added.
Ninety-five clinics throughout the state currently provide basic health care for poor women -- 30 percent of them teen-agers -- under federal Title X funds. The care covers such things as routine physicals, Pap smears, mammograms and blood pressure screenings.
Several of the practitioners said that if President Bush's veto is not overturned, they will defy it.

domain: medical


Guwahati, Sep 23 (PTI) Assam's COVID-19 tally went up to 1,63,491 after 2,098 positive cases were detected on Wednesday, while 11 more people succumbed to the disease taking the death toll to 597, Health and Family Welfare Minister Himanta Biswa Sarma said.
He said that 1,762 patients were also cured of the infection, pushing the total recoveries to 1,32,709. The recovery rate now is 81.17 per cent.
'Very sad and anguished to inform that eleven more COVID positive patients have succumbed to the disease.... My condolences to all the families. We stand by you in this hour of grief,' Sarma tweeted.
Of the fresh fatalities, two each were reported from Kamrup Metropolitan and Lakhimpur districts and one each from Sivasagar, Tinsukia, Nalbari, Kamrup Rural, Jorhat, Cachar and Chirang, the minister said.
The state now has 30,182 active cases, he said adding that three patients have migrated out of the state.
The 2,098 new cases included 505 from Kamrup Metropolitan, 172 in Jorhat, 160 in Dibrugarh and 152 in Lakhimpur among others, he said.
The fresh cases were detected out of 29,896 tests conducted during the day, while 30,21,508 samples were tested for COVID-19 in the state till date. PTI DG NN NN


text:
There is money in pets. Everybody got their Covid pet. So, it should come as no surprise that a new survey predicts huge growth in pet meal kit delivery services.
According to a report from market research company The Brainy Insights, pet meal kit delivery services are expected to grow $2.2 billion to $9 billion by 2030. That’s an annual growth rate of 15.9%. Pet meal kit delivery services are usually subscription-based and consumers get the food delivered right to their door.
“Global pet meal kit delivery market is witnessing considerable growth because pets are now considered members of the family,” according to the company. “Consumers’ willingness to spend more on pet food is shaped by the growing attachment between pet owners and their pets. Consumers are becoming more concerned of their pets’ health and are purchasing pet food with high nutritional value for their pets’ benefit. Pet owners nowadays are looking for pet consumables that are locally made, natural, or have unique health benefits, in addition to basic food products.”
Spot and Tango, Nom Nom, Pet Plate, The Farmer’s Dog, Chewy, Ollie, We Feed Raw, and Chi Dog were researched for the report. The company found that dogs dominate the segment. They make up 48% of the market. The report looked at pet meal kit delivery report services in North America, Europe, Asia-pacific, South America and the Middle East markets.
“North America region emerged as the largest market for the global pet meal kit delivery market with a 41.0% market share and a value of around $1 billion in 2020,” the report said. “The United States topped the North American pet meal kit delivery market. The market demand will be fuelled by an increase in the number of pet owners, increased awareness of veterinarian health, and changing demographic trends across the country. Furthermore, the industry will expand due to a rising move toward premium foods, followed by natural and organic foods.”

domain: pet


text:
Aberoth is an online multi-player real time persistent browser based role playing game. The peaceful land of Aberoth is under siege! Rogues are roaming the countryside. Ravenous rabbits are eating all of the crops. Ferocious bees are tormenting the citizens. Brave Champions are needed to rid the land of this scourge.
You start life as a simple peasant with nothing but your courage and bare hands. Will you become a Champion and help save your land?
- Status: Released
- Business Model: Free to Play
- Developer: Jarbit
- Publisher: Jarbit
- Category: Stand-alone, Browser
- Genre(s): 2D, MMO, Adventure, RPG, Fantasy
- Platforms: PC
- +150 unique items
- +Over 40 quests
- +14 large zones
- -Extreme 8-bit style may not appeal
- -Harsh penalties for death
- -Very limited tutorial
- Recommended System Requirements:
Aberoth will work on any computer that has an up to date version of Java installed.
Articles You May Enjoy
- World of Tanks 360 Version: Siberian Wolf Pack Update Available
- World of Tanks 360 Version: Siberian Wolf Pack Update Available - From the frozen Russian tundra and onto console
- Brave Frontier Mobile Review
- I didn’t really think much of Brave Frontier at first. I thought it would be the Farmville of the mobile app world, overplayed and hyped.
- Earthcore: Shattered Elements debuts on the App Store
- Tequila Games released today its free digital card battler Earthcore: Shattered Elements on the App Store for iPad and iPhone.

domain: game


text:
A very interesting study on dangerous bacteria that can survive on our money won an Ig Nobel prize
Recently the 2019 Ig Nobel prizes have been awarded at Harvard University. The idea behind the Ig Nobel awards is to celebrate unusual scientific achievements by making people laugh at first and then make them think about the subject at hand.
One of the award-winning studies that caught our eye this year focused on dirty money, literally. Dutch, German, and Turkish scientists worked together to find out which banknotes provide the best environment for dangerous bacteria to survive and potentially play a key role in bacterial transmissions from people to people.
The researchers studied paper money from different countries, including US dollar and Euro banknotes. First they inoculated some dangerous microorganisms: Methicillin-resistant Staphylococcus aureus (MRSA), Escherichia coli (E.coli / ESBL) and Vancomycin-resistant Enterococcus (VRE) into unused banknotes (These are types of bacteria that can cause problems in health care). Following that injection the researchers checked after 3, 6 and 24 hours if any of the dangerous bacteria were still alive.
The Croatian Kuna and Indian Rupee bills turned out to be the cleanest. At the first direct swab, the Croatian Kuna did not yield any of the three dangerous pathogens while the Indian Rupee only produced VRE. After 3 hours, scientists only found single colonies, and after six hours, the VRE bacteria had disappeared entirely.
It turns out that from all the bills that were tested the Romanian Leu scored the worst. This is probably due to a polymer fiber, used in the banknotes to prevent the creation of fake money, that appears to sustain bacteria for a long time. The Leu banknotes yielded all three multi-drug resistant pathogens that were tested (namely MSRA, VRE, and ESBL producing E.coli) at the first direct swab. In addition, all three types of bacteria still remained on the bills in large numbers after three hours and six hours. The Romanian Leu was also the only currency that still produced dangerous microorganisms (VRE) after 24 hours of drying.
Euro and Dollar banknotes
The European and American currencies performed somewhere in between the previously mentioned currencies. At the first direct swab, US dollar bills yielded large amounts of MRSA, multiple segments of VR, and a tiny amount of ESBL. Euro banknotes generated a small amount of VRE and a large amount of ESBL but no MRSA at their first swab.
After six hours, the MSRA had disappeared from the US dollar bills, and only small amounts of VRE and ESBL remained. Meanwhile, Euro bills only contained a small quantity of ESBL after that amount of time. Luckily all bacteria had disappeared on both currencies after 24 hours of drying.
Should we be worried?
Andreas Voss, one of the authors of the study, stated in an NPO interview that it is important for central banks to pay attention to dangerous bacteria when designing banknotes. However, people shouldn't be too worried as our immune systems should be able to handle a tiny amount of these bacteria.
Nonetheless, it is important to keep hygiene in mind. Simple things like washing your hands before touching your mouth, eyes, nose, and/or wounds should go a long way in preventing contamination.
If you enjoy our selection of content please consider following Universal-Sci on social media:


text:
18th century dresses with polonaise and closed front, thin wool broadcloth (the burgundy and marine blue ones) and tin wool twill (the green one). All worn over stays and linen or wool chemises.
This is three quarters of my group of alchemists for the swedish fantasy LARP Lazarus coming up in june 2012.
The black and green tricorne hats made by Tegelsten
Models (from left to right): me, Nanna, Micki

domain: artistic


text:
1 Kings 14:1-15:24 Holman Christian Standard Bible (HCSB)
Disaster on the House of Jeroboam
14 At that time Abijah son of Jeroboam became sick. 2 Jeroboam said to his wife, “Go disguise yourself, so they won’t know that you’re Jeroboam’s wife, and go to Shiloh. Ahijah the prophet is there; it was he who told about me becoming king over this people. 3 Take with you 10 loaves of bread, some cakes, and a jar of honey, and go to him. He will tell you what will happen to the boy.”
4 Jeroboam’s wife did that: she went to Shiloh and arrived at Ahijah’s house. Ahijah could not see; his gaze was fixed[a] due to his age. 5 But the Lord had said to Ahijah, “Jeroboam’s wife is coming soon to ask you about her son, for he is sick. You are to say such and such to her. When she arrives, she will be disguised.”
6 When Ahijah heard the sound of her feet entering the door, he said, “Come in, wife of Jeroboam! Why are you disguised? I have bad news for you. 7 Go tell Jeroboam, ‘This is what the Lord God of Israel says: I raised you up from among the people, appointed you ruler over My people Israel, 8 tore the kingdom away from the house of David, and gave it to you. But you were not like My servant David, who kept My commands and followed Me with all of his heart, doing only what is right in My eyes. 9 You behaved more wickedly than all who were before you. In order to provoke Me, you have proceeded to make for yourself other gods and cast images, but you have flung Me behind your back. 10 Because of all this, I am about to bring disaster on the house of Jeroboam:
I will eliminate all of Jeroboam’s males,[b]
12 “As for you, get up and go to your house. When your feet enter the city, the boy will die. 13 All Israel will mourn for him and bury him. He alone out of Jeroboam’s house will be put in the family tomb, because out of the house of Jeroboam the Lord God of Israel found something good only in him. 14 The Lord will raise up for Himself a king over Israel, who will eliminate the house of Jeroboam. This is the day, yes,[d] even today! 15 For the Lord will strike Israel and the people will shake as a reed shakes in water. He will uproot Israel from this good soil that He gave to their ancestors. He will scatter them beyond the Euphrates because they made their Asherah poles, provoking the Lord. 16 He will give up Israel because of Jeroboam’s sins that he committed and caused Israel to commit.”
17 Then Jeroboam’s wife got up and left and went to Tirzah. As she was crossing the threshold of the house, the boy died. 18 He was buried, and all Israel mourned for him, according to the word of the Lord He had spoken through His servant Ahijah the prophet.
19 As for the rest of the events of Jeroboam’s reign, how he waged war and how he reigned, note that they are written in the Historical Record of Israel’s Kings. 20 The length of Jeroboam’s reign was 22 years. He rested with his fathers, and his son Nadab became king in his place.
Judah’s King Rehoboam
21 Now Rehoboam, Solomon’s son, reigned in Judah. Rehoboam was 41 years old when he became king; he reigned 17 years in Jerusalem, the city where Yahweh had chosen from all the tribes of Israel to put His name. Rehoboam’s mother’s name was Naamah the Ammonite.
22 Judah did what was evil in the Lord’s eyes. They provoked Him to jealous anger more than all that their ancestors had done with the sins they committed. 23 They also built for themselves high places, sacred pillars, and Asherah poles on every high hill and under every green tree; 24 there were even male cult prostitutes in the land. They imitated all the detestable practices of the nations the Lord had dispossessed before the Israelites.
25 In the fifth year of King Rehoboam, Shishak king of Egypt went to war against Jerusalem. 26 He seized the treasuries of the Lord’s temple and the treasuries of the royal palace. He took everything. He took all the gold shields that Solomon had made. 27 King Rehoboam made bronze shields in their place and committed them into the care of the captains of the royal escorts[e] who guarded the entrance to the king’s palace. 28 Whenever the king entered the Lord’s temple, the royal escorts would carry the shields, then they would take them back to the royal escorts’ armory.
29 The rest of the events of Rehoboam’s reign, along with all his accomplishments, are written about in the Historical Record of Judah’s Kings. 30 There was war between Rehoboam and Jeroboam throughout their reigns. 31 Rehoboam rested with his fathers and was buried with his fathers in the city of David. His mother’s name was Naamah the Ammonite. His son Abijam[f] became king in his place.
Judah’s King Abijam
15 In the eighteenth year of Israel’s King Jeroboam son of Nebat, Abijam became king over Judah 2 and reigned three years in Jerusalem. His mother’s name was Maacah daughter[g] of Abishalom.
3 Abijam walked in all the sins his father before him had committed, and he was not completely devoted to the Lord his God as his ancestor David had been. 4 But because of David, the Lord his God gave him a lamp in Jerusalem to raise up his son after him and to establish Jerusalem. 5 For David did what was right in the Lord’s eyes, and he did not turn aside from anything He had commanded him all the days of his life, except in the matter of Uriah the Hittite.
6 There had been war between Rehoboam and Jeroboam all the days of Rehoboam’s life. 7 The rest of the events of Abijam’s reign, along with all his accomplishments, are written in the Historical Record of Judah’s Kings. There was also war between Abijam and Jeroboam. 8 Abijam rested with his fathers and was buried in the city of David. His son Asa became king in his place.
Judah’s King Asa
11 Asa did what was right in the Lord’s eyes, as his ancestor David had done. 12 He banished the male cult prostitutes from the land and removed all of the idols that his fathers had made. 13 He also removed his grandmother[j] Maacah from being queen mother because she had made an obscene image of Asherah. Asa chopped down her obscene image and burned it in the Kidron Valley. 14 The high places were not taken away; but Asa’s heart was completely devoted to the Lord his entire life. 15 He brought his father’s consecrated gifts and his own consecrated gifts into the Lord’s temple: silver, gold, and utensils.
16 There was war between Asa and Baasha king of Israel throughout their reigns. 17 Israel’s King Baasha went to war against Judah. He built Ramah in order to deny anyone access to Judah’s King Asa. 18 So Asa withdrew all the silver and gold that remained in the treasuries of the Lord’s temple and the treasuries of the royal palace and put it into the hands of his servants. Then King Asa sent them to Ben-hadad son of Tabrimmon son of Hezion king of Aram who lived in Damascus, saying, 19 “There is a treaty between me and you, between my father and your father. Look, I have sent you a gift of silver and gold. Go and break your treaty with Baasha king of Israel so that he will withdraw from me.”
20 Ben-hadad listened to King Asa and sent the commanders of his armies against the cities of Israel. He attacked Ijon, Dan, Abel-beth-maacah, all Chinnereth, and the whole land of Naphtali. 21 When Baasha heard about it, he quit building Ramah and stayed in Tirzah. 22 Then King Asa gave a command to everyone without exception in Judah, and they carried away the stones of Ramah and the timbers Baasha had built it with. Then King Asa built Geba of Benjamin and Mizpah with them.
23 The rest of all the events of Asa’s reign, along with all his might, all his accomplishments, and the cities he built, are written in the Historical Record of Judah’s Kings. But in his old age he developed a disease in his feet. 24 Then Asa rested with his fathers and was buried in the city of his ancestor David. His son Jehoshaphat became king in his place.
Acts 10:1-23 Holman Christian Standard Bible (HCSB)
10 There was a man in Caesarea named Cornelius, a centurion of what was called the Italian Regiment. 2 He was a devout man and feared God along with his whole household. He did many charitable deeds for the Jewish people and always prayed to God. 3 About three in the afternoon[a] he distinctly saw in a vision an angel of God who came in and said to him, “Cornelius!”
4 Looking intently at him, he became afraid and said, “What is it, lord?”
The angel told him, “Your prayers and your acts of charity have come up as a memorial offering before God. 5 Now send men to Joppa and call for Simon, who is also named Peter. 6 He is lodging with Simon, a tanner, whose house is by the sea.”
7 When the angel who spoke to him had gone, he called two of his household slaves and a devout soldier, who was one of those who attended him. 8 After explaining everything to them, he sent them to Joppa.
9 The next day, as they were traveling and nearing the city, Peter went up to pray on the housetop about noon.[b] 10 Then he became hungry and wanted to eat, but while they were preparing something, he went into a visionary state. 11 He saw heaven opened and an object that resembled a large sheet coming down, being lowered by its four corners to the earth. 12 In it were all the four-footed animals and reptiles of the earth, and the birds of the sky. 13 Then a voice said to him, “Get up, Peter; kill and eat!”
14 “No, Lord!” Peter said. “For I have never eaten anything common[c] and ritually unclean!”
15 Again, a second time, a voice said to him, “What God has made clean, you must not call common.” 16 This happened three times, and then the object was taken up into heaven.
Peter Visits Cornelius
17 While Peter was deeply perplexed about what the vision he had seen might mean, the men who had been sent by Cornelius, having asked directions to Simon’s house, stood at the gate. 18 They called out, asking if Simon, who was also named Peter, was lodging there.
19 While Peter was thinking about the vision, the Spirit told him, “Three men are here looking for you. 20 Get up, go downstairs, and accompany them with no doubts at all, because I have sent them.”
21 Then Peter went down to the men and said, “Here I am, the one you’re looking for. What is the reason you’re here?”
22 They said, “Cornelius, a centurion, an upright and God-fearing man, who has a good reputation with the whole Jewish nation, was divinely directed by a holy angel to call you to his house and to hear a message from you.” 23 Peter then invited them in and gave them lodging.
The next day he got up and set out with them, and some of the brothers from Joppa went with him.
Psalm 133 Holman Christian Standard Bible (HCSB)
Living in Harmony
A Davidic song of ascents.
1 How good and pleasant it is
Proverbs 17:7-8 Holman Christian Standard Bible (HCSB)
7 Eloquent words are not appropriate on a fool’s lips;
8 A bribe seems like a magic stone to its owner;

domain: literature


text:
Cape of Good Hope
Good for: animals, Photo Opportunities, wine tasting, Driving
Lonely Planet review for Cape of Good Hope
Commonly called Cape Point, this 7750-hectare section of Table Mountain National Park, includes awesome scenery, fantastic walks and often deserted beaches. Some 250 species of birds live here, including cormorants and a family of ostriches that hang out near the Cape of Good Hope, the southwesternmost point of the continent.
Many people visit on organised bus tours but, if you have the time, exploring the reserve on foot or by bicycle is much more rewarding. Bear in mind, though, that there is minimal shade and that the weather can change quickly. Bookings are required for the two-day Cape of Good Hope Trail, a spectacular 33.8km circular route with one night spent at the basic Protea and Restio huts. Contact the Buffelfontein Visitors Centre for further details.
It’s not a hard walk uphill, but if you’re feeling lazy the Flying Dutchman Funicular runs up from beside the restaurant to the souvenir kiosk next to the old lighthouse, dating from 1860. A 1km trail runs from here to its successor. Ignore the signs: it takes less than 30 minutes to walk along a spectacular ridgeway path to look down on the new lighthouse and the sheer cliffs plunging into the pounding ocean.

domain: geography


Days after some students participated in a silent protest against the “vegetarian-only” tables designated by one of the mess councils at the Indian Institute of Technology (IIT) Bombay, the institute imposed a hefty fine to the tune of Rs 10,000 on one of the students while it resolved to identify two others for the “premeditated attempt to disrupt the peace and harmony of the mess”, News18 has learnt.
On Monday, an email by the hall manager of one of the hostels addressed to the protesting student read: “…I am to inform you that the authority has imposed on you a fine of Rs 10,000 (Ten Thousand only), which will be deducted from your SMA account.”
The email communication came after a meeting of the mess councils of ‘Hostels 12, 13 and 14’ on Sunday afternoon, which included hostel wardens and associate wardens to discuss the complaints about the “unruly behaviour and flouting of mess rules by a few students” during dinner on September 28, read the minutes of the meeting seen by News18.
According to the document, the mess council reviewed the evidence available and determined that a resident of hostel 12 (name withheld), deliberately “instigated” the incident during dinner on September 28. “This act was a premeditated attempt to disrupt the peace and harmony within the mess in defiance of the advice provided by the associate dean, SA, as evidenced in shared email communication. At least two other individuals were involved, whose identities are yet to be ascertained,” it stated.
script async src="https://pagead2.googlesyndication.com/pagead/js/adsbygoogle.js?client=ca-pub-2456890113413633"
The minutes further said that it was unanimously agreed that the behaviour of the student in question was “contrary to the inclusive and peaceful atmosphere at hostels 12, 13 and 14 (which have a combined mess) mess. “The mess council resolved to impose a fine of Rs 10,000 on the student,” it stated.
The institute did not respond to News18’s queries regarding the move. This story will be updated if and when a response is received.
During the meeting that was attended by four professors and three mess staffers, they also resolved to enlist the support of student representatives from the three hostels in “identifying the other two individuals involved in the incident. Once their identities are established, appropriate disciplinary action will be taken against them as well”.
Ambedkar Periyar Phule Study Circle (APPSC), an informal student collective active on the IITB campus, while terming the action of the institute similar to that of a Khap Panchayat said that the students had protested against the segregation of tables in the mess based on veg and non-veg food by a peaceful act of civil disobedience. “This action of the admin is similar to a Khap Panchayat acting to uphold untouchability in modern times. We condemn this tyrannical decision of the admin and urge to reverse the regressive policy immediately,” it said in a statement.
The move comes after an email communication by the mess council of hostels 12, 13, and 14 on September 27 designated six tables in the mess where only vegetarian food will be taken by everyone. The email underlined that the decision was being taken to make the dining experience “more inclusive for all” and stated that “there was no doubt that some people who cannot resist the view and smell of non-veg food during dining ..which may create health issues as well”, sparking a controversy. It ended up with several students leading a silent protest while some of them sat at the designated tables to deliberately eat non-veg food as a mark of protest on September 28.


text:
The repo rate cut and the surfeit of liquidity, sparked off another round of gains. However, at these levels the yields are unsustainable.
01-Jun-2001 •Markets Desk
Well aided by the comfortable liquidity in the system since last week, the RBI moved to signal softening of the short term interest rates by slashing its repo rate by 25 basis points to 6.50 per cent. With the repo rate cut, the differential between the repo and reverse repo rate stands widened at 2.25 per cent. Even as the RBI sucked out close to Rs. 34405 crores through its repo deals, with players covering their positions ahead of the reporting Friday, call rates ruled low in the 6.75-7 per cent range. Amid the comfortable liquidity, the yield in the 91 and 364 day Treasury bill auction dropped by 37 basis points.
This offered a smooth sail to the twin auction of GOI securities two Central Government papers-GOI 2013 and GOI 2021, which were hugely over subscribed. The lower than expected cut-off yield in the auctions, further signaling the bank's preference for softer interest rates, sparked off another round of gains in Government Securities, thus pushing the yields to dizzier lows. Currently the yield on 11.50% GOI 2011 is 9.806%, which is well below the ideal spread of 3.25-.50 per cent over the bank rate. This many market players feel is unsustainable. In a bid to maintain the comfortable liquidity, the center placed Rs 5000 crore worth of Central Government 2021 with RBI, thus completing over 35% of it gross borrowing programme.
The rally is spilling over to the corporate bond segment, which witnessed gains accompanied by increased trading volumes. In the backdrop of the CRR and the repo rate cut, primary activity too picked up as corporates moved in to cash in on the easy liquidity and are slated to bring forth new issues worth Rs 1200 crore in the next week.
With the month end dollar demand taking the rupee to Rs 47 levels, steady supplies ensured that the rupee stayed range bound. However, with the international rating agency Fitch revising India's sovereign ratings outlook to negative from stable, it closed the week lower at Rs 47.01. The forward premia opened the week at lower levels than the previous week's levels but close at marginally higher levels following the spot rupee.
With expectation of a bank rate cut already discounted for, the eventual rate cut may not offer any much fresh gains. With the market players perceiving the rupee to be over-valued the RBI may not be averse to the rupee sliding a bit lower. However, with FIIs turning net sellers in the light of the FITCH downgrade, a sustained selling could put pressure on the INR. The Government has pruned expenses to hold last year's fiscal deficit at 5.21% against the estimated 5.1%. However, with the bleak economic outlook and the possibility of lower revenue collection, doubts about the size of the current years borrowing do arise. This is likely to put pressure on interest rates in the medium term.

domain: economics


text:
It is the color of vegetation, calmness, relaxation, and toning. It symbolizes life, hope, and immortality, although it also can indicate poison or unexpected dangers when associated with the jungle. Green represents irrational instinct. If you dream that this color appears in the middle of a desert scenery, it signifies that you are going through a period of unproductivity, but that you will soon leave this period. However, an excess of green evidences that you get carried away by your instincts. If you are in the middle of some sort of resolution, the presence of this color advises you to wait until things mellow.
Gallery of dreams
Reading in dream
Sometimes you will not be able to differentiate lucid dream. If you want to be sure, try reading a simple sentence, if you are able to read then you are in wakeful stage if not you are in lucid dreaming. Studies show that you cannot read while dreaming or you will not find the repeated sentences one more time.
One of the reasons why people always get involved in road accidents is that, they are tired while driving, or that they lack sleep. Many people do not realize that their performance can be highly affected by having not enough sleep. Sleep deprivation can affect reaction as well as decision making, not to mention that it could make a person unable to drive well. It goes the same with drunk driving.

domain: psychology


text:
Add Something New to Your Daily Activities
When was the last time you opened a cookbook and took a shot at expanding your culinary knowledge? So many people don’t find time to cook or try new recipes, which is hard to understand since cooking can be such a relaxing and rewarding activity! Of course, we’re not talking about French fries or mashed potatoes. Instead, grab some friends and sweeten it up with a crazy dessert recipe!
Don’t be afraid to create a mess—the first try is never perfect. Fancy hot chocolate is always a terrific start if you want to start small. Whipped cream, sprinkles, cookies, berries, marshmallows—anything you can think of, you can add into the cup.
Next, look through your wardrobe. Find a T-shirt that you already know hasn’t been your favorite lately. Then, buy a tie-dye kit and let your imagination fly sky high! Create something unique while having fun at the same time.
One thing is sure—we always style our hair, and mostly we style it with monotony. It’s time to mix it up by challenging yourself and trying new hairstyles every day. French braids and ponytails always bring back that youthful feeling we all need in our lives.
Pick Up New Hobbies
There is no shame in trying something new because you never know what you might enjoy. Knitting always seems like the hobby everyone wants to get on but never does. So, challenge your creativity and create a blouse, scarf or even a simple coaster. We all have to begin somewhere.
Braiding bracelets is also a refreshing hobby if you think knitting is not for you. Pick up a pattern and create bracelets for your friends or family. This hobby allows the finished product to be gifted and keeps your mind sharp.
Maybe hobbies that involve your hands and body are not your type. But there are always alternatives for everyone. One of the oldest and most known hobbies is reading. The variety of genres and authors will keep you engaged, help you learn new words and train your mind!
Not a fan of the written or printed word? Audiobooks are always a splendid alternative! You can listen to an audiobook when taking a bath, mowing your lawn or doing household chores. It is phenomenal how audiobooks allow you to kill two birds with one stone!
If you feel like taking up a hobby that involves exercising and being fun simultaneously, buy either a hula hoop, a yoga mat or a jumping rope. These exercises require very little time from your schedule and give you the boat of energy you need.
Do Something That Makes You Feel Young
Dancing is an activity that brings out youthfulness in everyone! It is a fun way of exercising that allows for infinite versatility—you can never get bored of it! So, grab a couple of friends and throw a dancing party every now and then, with different thematics and costumes.
Grab some makeup and try that look you were too afraid to see on you. Use that shade from your pallet you never touched, draw that big wing you always feared and put on the most scandalous lipstick color you own.
Video games are such a big part of teens’ lives right now, so why not give them a try? There are endless video games from which you can choose. You have to find something that brings you joy and can keep you hooked. Maybe you will enjoy gardening games or the ones involving strategy—it doesn’t matter. Video games keep your mind young and train your reflexes.
Have some friends and pull out that dusted Scrabble game from the wardrobe! Board games such as backgammon, Monopoly, chess, Sorry!, Rummy and Pictionary are always great when played with friends.
Every young teen had a journal in which they wrote anything that flew through their mind. And, of course, somehow, it always ended up in your mother’s hands. But now it’s yours and yours only. So, vent your feelings in a journal, and you will feel exactly like a teenager.
Rewatch your favorite series or childhood cartoon, and don’t forget the popcorn. So what if you already watched it a hundred times? That’s why it is your favorite! Grab a cozy blanket and a comfortable pillow and start binging.
Go for a picnic in the park with your significant other or some friends. Prepare small sandwiches and some refreshing apple juice that will make you feel like a small child.
Listen to a podcast while driving to work. This will keep you curious until you return for your drive back home. I bet your favorite YouTuber has a podcast, so start from there!
This may seem like a chore, but organizing and reorganizing your home can bring you joy! It doesn’t have to be anything huge. Start by grabbing those used napkins from your desk and organizing your books and plants.
Go to the park and jump on the first swing you see. I bet you will get some looks thrown at you, but worrying about it should be your last problem. Feel like a kid again and allow no one to stop you!
Grab some fresh flowers that will improve the scenery of your house. Flowers do not have to be gifted to you by someone all the time. Instead, you can head to the flower shop by yourself and grab the first bouquet that stands out.
Lastly, you can always grab your fanciest clothes and have a dress-up by yourself, just like when you were young. You are never too old for dress-up, but you can wear your clothes this time instead of your mum’s.
A Parting Reminder
Many activities can bring joy to your life, but first, you have to find out which ones are perfect for you. Never be afraid to explore your possibilities and do what makes you feel young. Then, you can spread the joy and ask your friends to join in for a great day!


text:
There is a brand new game available online and this Roulette variant is the global Roulette game, it comes in several different formats, however the main attraction of this game is the fact that a new game will start in a set number of seconds, you simply need to pick one that is ideal for the way you play and then get playing it!
Where to Play Global Roulette
Fairway Casino is a brand new online casino which offers you the ability to not only site down and play real Live Roulette but you can also play a range of software driven casino games, and one of these games is the Global Roulette game which offers a fast paced, all action type of playing style, ideal when you haven\’t time to waste waiting for the next game to start.
Global Roulette Bets and Payouts
Unique Global Roulette Features – The best thing about playing Global Roulette is that you will be able to set it to play your own preferred favourite sets of numbers, this allows you to put them into play with one click of your mouse whenever you want to wager on these sets of numbers. Meaning the game is much quicker to play.
When playing Global Roulette you can place several bets which are known as inside bets, these are all located in the inner section of the Global Roulette betting layout are are as follows:
Global Roulette Straight Up Bet – To place a Straight Up bet when playing Global Roulette simply put your chip directly onto the number you have chosen, and if it spins in your wagered amount is paid out at odds of 35 to 1.
Global Roulette Split Bet – This wager lets you play two numbers for one bet, simply place your chip onto the Global Roulette table on the line which divides the two numbers you wish to wager on, and if either of them spin in then you will receive a payout worth 17 to 1 of your wagered amount on that bet.
Global Roulette Street Bet – Should you wish to cover three numbers which are side by side on the Global Roulette betting layout then you need to place your wager on the outside line of these three numbers, and should any one of them spin in a payout of 11 to 1 of your staked amount is awarded to you.
Global Roulette Square Bet – There are several numbers on the Global Roulette betting layout which are all side by side, and as such you can wager on any four of these numbers by placing your chip directly onto the centre spot of these four numbers, should any four of them spin in a payout of 8 to 1 is awarded to you.
Global Roulette Line Bet – This Global Roulette betting option lets you cover any six numbers which are adjacent to each other, a payout of 5 to 1 is awarded should any of them spin in and you will need to put your chip on the the line which separates these six numbers.
The Global Roulette variant also features range of Outside Bets, and as the name of these wagers suggests, these are found on the outside section of the Global Roulette betting layout and these are as follows:
Global Roulette Column Bets – To cover all twelve numbers on any of the three columns found on the betting layout of the Global Roulette table then simply place your chip on the empty box at the top of one of these columns. Should any of those twelve numbers spin in a payout worth 2 to 1 of your total staked amount is awarded.
Global Roulette Dozen Bets – You can cover any set of the twelve low, middle or high numbers found on the Global Roulette table, simply place your chip on the First 12, Second 12 or Third 12 betting locations on the tables betting layout and if any of the numbers covered by these spin in, when you have placed a wager on them, then a payout worth 2 to 1 is awarded to you.
Global Roulette Even Money Bets – These are the easiest and most popular wagers to place on the Global Roulette table. When you want to place an even money wager of which you have six of them available which are the Even, Odd, Red, Black, 1-18 or 19-36 groupings simply put your chip or chips on the relevant betting box, and when any of your wagered numbers spin in then a payout of even money is awarded.


text:
President Trump visited the Yad Vashem Holocaust museum in Jerusalem Tuesday afternoon, laying a wreath in honor of the six million victims of the Nazi Holocaust. Read more
The Yad Vashem Holocaust Museum on Tuesday announced that the late Master Sergeant Roddie Edmonds has been posthumously recognized as a Righteous Among the Nations, marking the first US soldier recognized with the honor. Read more
T.O.T. Private consulting
T.O.T. Private Consulting specializes in a variety of services for the Orthodox Jewish community worldwide.


supplier for ball mill spares - makabsworg Grinding Mills - - supplier for ball mill spares ,the design and supply of top quality grinding mills Grinding mills.
Welcome to buyers from Lesotho Alloy industrial rotary file, and we've provided Lesotho buyers with great service, , Ball mill wear parts; Bead mill wear parts;.
ball mill israel for sale - holycross-intl Ball Mill For Hematite For Sale Supplier, Find Best Ball Mill For ,- ball mill israel for sale , Find Best Ball Mill For.
Ball Mill Spare Parts, Wholesale Various High Quality Ball Mill Spare Parts Products from Global Ball Mill Spare Parts Suppliers and Ball Mill Spare Parts Factory.
mill for grinding spares in mumbai Grinding Mill Parts,Stone Grinding Mill Parts,Ball Grinding Grinding Mill Parts Wheat Grinding Machine in Mumbai - Flour Mill.
Alibaba offers 8,507 ball mill parts products About 43% of these are mine mill, 3% are mining machinery parts, and 1% are machining A wide variety of ball mill.
Ball mill balls supplier Working Principle of ball mill balls The ball mill is a horizontal rotating device transmitted by the outer gear The materials are.
supplier for ball mill spares lesothobuy ball mill spare parts high qualitytrade leads from ball mill spare parts suppliers and ball mill spare parts buyers.
Matcon Industries provides best services in , We are established manufacturer and supplier of various Plant, Mill , Cement Mill Machine Spare Parts: Ball Mill.
Find details about China Electrically Calcined Anthracite Coal,vega vertical mill spares; , supplier for ball mill spares lesotho - Quarry Machine.
supplier for ball mill spares lesotho manganese wear parts suppliers in south africa Iran manganese wear parts suppliers in south africa india,manganese wear.
Ball Mill Spare Parts Supplier - crckilaorg coal mill spare parts supplier - stone crusher coal mill spare parts supplier is manufactured from Shanghai Xuanshi,We.
Ball Mill Spares Supplier Request a quotation FirstChoice (Group) Canada : Exporter : Importer FirstChoice (Group) Canada, Exporter, Importer, Supplier.
Ball Mill Liners, Ball Mill Liners Suppliers and Manufacturers at Related Searches for ball mill liners cone liner ball mill spare parts ball mill rubber liner ball.
Find Ball Mill manufacturers from China Import quality Ball Mill supplied by experienced manufacturers at Global Sourc.
Spare Parts Supply & Management >Service >, POLYCOM HPGR ball mill grinding circuit Wet grinding plantsWith good, forward-looking spare parts management, you.
supplier for ball mill spares Hot Product HPC Cone Crusher Base on the latest technology and decades of years’ producing experience, OGG designed the.
Welcome to buyers from Lesotho Carbide Pump Shaft Sleeves for Oil Industry, , Ball mill wear parts; Bead mill wear parts;.
ball mill spare parts supplier As a leading global manufacturer of crushing, grinding and mining equipments, we offer advanced, reasonable solutions for any size.
Supplier For Ball Mill Spares Lesotho - CRUSHING PLANT , Ball Mill Suppliers In South Africa,Crusher South Africa Products/Services : Pumps,Crusher Spares,Ball.
ball mill spares supplier Supplier For Ball Mill Spares Lesotho supplier for ball mill spares Ball Mill Spares Supplier - , Ball Mill, Parts and Spares, Ball Mill.
Ball Mill Parts, Ball Mill Parts Suppliers and Manufacturers, Wholesale Various High Quality Ball Mill Parts Products from Global Ball Mill Parts Suppliers and Ball.
ball mill spare parts supplier,ball mill part for sale in Iran Chat With Sal supplier for ball mill sparesHOTEL Atithi , supplier for ball mill spares lesotho.
Rubidium Oscillator Quartz , Find RoHS Compliant Rubidium Crystal Oscillator related suppliers, , supplier for ball mill spares lesotho.
Supplier For Ball Mill Spares Lesotho , spare parts for ball mill suppliers ball mill spares supplier Ball Mill Spare Parts for Sale, Best Price.
supplier for ball mill spares lesotho - Grinding Mill ChinaBall Mill Spare Parts, Ball Mill Spare Parts direct from Ball Mill Spare Parts from Zhengzhou Yusheng.
Bradken Mill Liners Bradken is a leading international supplier of high quality Mill Liner systems to suit AG/SAG Mills, Rod Mills, Cement Mills and Ball Mills.
ball mill spare parts supplier,ball mill part for sale in Iran ball mill is best andmost efficiently suited plant cement grinding mill zenith supplies you.


‘Interfering in internal matters’: China slams US for visa restrictions over abuse of Uighur Muslims
Beijing (USA) | Jagran News Desk: The United States on Tuesday imposed restrictions on visas of the Chinese government and Communist party officials till Beijing ends its ‘repression’ of Uighur Muslims in the Xinjiang region of the country.
Secretary of State Mike Pompeo cited the decision of the Commerce Department on Monday to add 28 Chinese public security bureaus and companies - including video surveillance company Hikvision - to a US trade blacklist over Beijing's treatment of Uighur Muslims and other predominantly Muslim ethnic minorities.
“China has forcibly detained over one million Muslims in a brutal, systematic campaign to erase religion and culture in Xinjiang,” Pompeo said in a Tweet.
“China must end its draconian surveillance and repression, release all those arbitrarily detained and cease its coercion of Chinese Muslims abroad,” he added.
However, the Chinese Embassy in Washington slammed the move by the US government and said that it is ‘interfering’ in its internal matter.
“The US decision seriously violates the basic norms governing international relations, interferes in China's internal affairs and undermines China's interests. China deplores and firmly opposes that,” said the Chinese Embassy in a tweet.
“Xinjiang does not have the so-called human rights issue claimed by the US. The accusations by the US side are merely made-up pretexts for its interference,” it added.
This is not the first time when the US has raised the Uighur Muslim issue. The US has been increasingly vocal denunciations about China's actions in Xinjiang. Last week, Pompeo had alleged that China "demands its citizens worship government, not God" in a press conference in the Vatican. While in July more than 20 countries at the UN Human Rights Council signed a joint letter criticising China's treatment of the Uighurs and other Muslims.
(With Reuters inputs)
Posted By: Aalok Sensharma


text:
- Rosiglitazone Elicits an Adiponectin-Mediated Insulin-Sensitizing Action at the Adipose Tissue-Liver Axis in Otsuka Long-Evans Tokushima Fatty Rats. [Journal Article]
- JDJ Diabetes Res 2018; 2018:4627842
- Rosiglitazone is an agonist of peroxisome proliferator-activated receptor- (PPAR-) γ that is principally associated with insulin action. The exact mechanisms underlying its insulin-sensitizing action...
Rosiglitazone is an agonist of peroxisome proliferator-activated receptor- (PPAR-) γ that is principally associated with insulin action. The exact mechanisms underlying its insulin-sensitizing action are still not fully elucidated. It is well known that adiponectin mostly secreted in adipose tissue is an insulin sensitizer. Here, we found that treatment of Otsuka Long-Evans Tokushima Fatty (OLETF) rats with rosiglitazone (3 mg/kg, once daily, by oral gavage for 33 weeks) attenuated the increase in fasting plasma insulin concentrations and the index of the homeostasis model assessment of insulin resistance along with the age growth and glucose concentrations during an oral glucose tolerance test. In addition, the increase in plasma alanine aminotransferase activity, concentrations of fasting plasma nonesterified fatty acids and triglyceride, and hepatic triglyceride content was also suppressed. The hepatic protein expression profile revealed that rosiglitazone increased the downregulated total protein expression of insulin receptor substrate 1 (IRS-1) and IRS-2. Furthermore, the treatment suppressed the upregulated phosphorylation of IRS-1 at Ser307 and IRS-2 at Ser731. The results indicate that rosiglitazone ameliorates hepatic and systemic insulin resistance, hepatic inflammation, and fatty liver. Mechanistically, rosiglitazone suppressed hepatic protein overexpression of both phosphorylated nuclear factor- (NF-) κBp65 and inhibitory-κB kinase-α/β, a transcription factor that primarily regulates chronic inflammatory responses and the upstream NF-κB signal transduction cascades which are necessary for activating NF-κB, respectively. More importantly, rosiglitazone attenuated the decreases in adipose adiponectin mRNA level, plasma adiponectin concentrations, and hepatic protein expression of adiponectin receptor-1 and receptor-2. Thus, we can draw the conclusion that rosiglitazone elicits an adiponectin-mediated insulin-sensitizing action at the adipose tissue-liver axis in obese rats. Our findings may provide new insights into the mechanisms of action of rosiglitazone.
- Actions of the National Regulatory Authorities in 10 Low- and Middle-Income Countries Following Stringent Regulatory Authority Safety Alerts on Rosiglitazone. [Journal Article]
- TITher Innov Regul Sci 2015; 49(2):279-283
- On September 23, 2010, the US Food and Drug Administration and the European Medicines Agency issued safety alerts for medicines containing rosiglitazone. The authors monitored the actions of national...
On September 23, 2010, the US Food and Drug Administration and the European Medicines Agency issued safety alerts for medicines containing rosiglitazone. The authors monitored the actions of national regulatory authorities (NRAs) from 10 low- and middle-income countries to identify the time lag between the issuance of safety alerts by these two stringent regulatory authorities and any actions by these select NRAs. Two NRAs outside Africa took regulatory actions related to safety of rosiglitazone within 2 weeks of stringent regulatory authority safety alerts. For the 7 of the 8 African NRAs where the authors could confirm the date of regulatory action, the median time lag before some regulatory action was 43 days, although there was considerable variability in time to regulatory action. Low- and middle-income countries should create or strengthen systems for timely consideration and management of emerging safety issues for products that they have registered.
- Impairment of bisphenol F on the glucose metabolism of zebrafish larvae. [Journal Article]
- EEEcotoxicol Environ Saf 2018 Sep 12; 165:386-392
- Bisphenol F (BPF) is a substitute of bisphenol A in the production of epoxy resin and polycarbonate. Its extensive use in consumer products leads to a wide human exposure at high levels. Although the...
Bisphenol F (BPF) is a substitute of bisphenol A in the production of epoxy resin and polycarbonate. Its extensive use in consumer products leads to a wide human exposure at high levels. Although the adverse effects of BPF on animal health are of increasing public concern, its risks on systematic glucose metabolism and blood glucose concentrations still remain largely unknown. Using zebrafish larvae as the model animal, we investigated the disturbance of BPF exposure on glucose metabolism and the underlying mechanisms. Zebrafish larvae at 96 h post fertilization were exposed to 0.1, 1, 10, and 100 μg/L of BPF for 48 h. Compared with the control group, glucose levels of larvae increased significantly in the 10 and 100 μg/L exposure groups, which are associated with enhancement of gluconeogenesis and suppression of glycolysis induced by high doses of BPF. Additionally, both mRNA expressions and protein levels of insulin increased significantly in the 10 and 100 μg/L exposure groups, while transcription levels of genes encoding insulin receptor substrates decreased significantly in these groups, indicating a possibly decreased insulin sensitivity due to impairment of insulin signaling transduction downstream of insulin receptor. Further, compared with BPF alone, co-exposure of larvae to BPF and rosiglitazone, an insulin sensitizer, significantly attenuates increases in both glucose levels and mRNA expressions of a key gluconeogenesis enzyme. Our data therefore indicate impairing insulin signaling transduction may be the main mechanism through which BPF disrupts glucose metabolism and induces hyperglycemia. Results of the present study inform the health risk assessment of BPF and also suggest the use of zebrafish larvae in large-scale screening of chemicals with possible glucose metabolism disturbing effect.
- Di-n-butyl phthalate modifies PMA-induced macrophage differentiation of THP-1 monocytes via PPARγ. [Journal Article]
- TVToxicol In Vitro 2018 Sep 12
- The present study examined effects of di-butyl phthalate (DBP) on phorbol myristate acetate (PMA)-induced macrophage differentiation of THP-1 monocytes, determined by morphological classification and...
The present study examined effects of di-butyl phthalate (DBP) on phorbol myristate acetate (PMA)-induced macrophage differentiation of THP-1 monocytes, determined by morphological classification and flow cytometry. Focusing on expression of the surface marker CD36, the potential role of peroxisome proliferator-activated receptor gamma (PPARγ) was examined using various PPARγ agonists and antagonists. As the PPARγ ligand-binding domain contains multiple ligand-binding sites (LBS), agonist and antagonists targeting the different sites were used. DBP accelerated PMA-induced morphological changes and increased expression of CD36, although to a lesser degree than the PPARγ agonists rosiglitazone and 15-deoxy-Δ12,14-prostaglandin J2 (15d-PGJ2). A proteomics screening revealed that DBP enhanced expression of PPARγ-regulated proteins. During combined exposures, DBP partly attenuated the effect of rosiglitazone, an agonist binding reversibly to PPARγ's canonical LBS. In contrast, DBP increased expression of CD36 in combination with 15d-PGJ2 which binds irreversibly to the canonical LBS. Thus, DBP appears to interact with both the canonical and alternative LBS. In line with this, the antagonist GW9662 binding to the canonical LBS, only partly reduced DBP effects on CD36, while the dual-site PPARγ antagonist SR16832 completely blocked the effects of DBP. Overall, the results show that DBP modifies PMA-induced differentiation of THP-1 cells through interaction with PPARγ.
- Inhibiting role of rosiglitazone in the regulation of inflammatory response and protective effects for severe acute pancreatitis in mice. [Journal Article]
- JCJ Cell Biochem 2018 Sep 11
- CONCLUSIONS: Rosiglitazone could protect mice with SAP from injury by downregulating Socs3 and inhibiting the inflammatory response pathway.
- Identification of the First PPARα/γ Dual Agonist Able To Bind to Canonical and Alternative Sites of PPARγ and To Inhibit Its Cdk5-Mediated Phosphorylation. [Journal Article]
- JMJ Med Chem 2018 Sep 18
- A new series of derivatives of the PPARα/γ dual agonist 1 allowed us to identify the ligand ( S)-6 as a potent partial agonist of both PPARα and γ subtypes. X-ray studies in PPARγ revealed two differ...
A new series of derivatives of the PPARα/γ dual agonist 1 allowed us to identify the ligand ( S)-6 as a potent partial agonist of both PPARα and γ subtypes. X-ray studies in PPARγ revealed two different binding modes of ( S)-6 to the canonical site. However, ( S)-6 was also able to bind an alternative site as demonstrated by transactivation assay in the presence of a canonical PPARγ antagonist and supported from docking experiments. This compound did not activate the PPARγ-dependent program of adipocyte differentiation inducing a very less severe lipid accumulation compared to rosiglitazone but increased the insulin-stimulated glucose uptake in 3T3-L1 adipocytes. Finally, ( S)-6 inhibited the Cdk5-mediated phosphorylation of PPARγ at serine 273 that is currently considered the mechanism by which some PPARγ partial agonists exert antidiabetic effects similar to thiazolidinediones, without showing their typical side effects. This is the first PPARα/γ dual agonist reported to show this inhibitory effect representing the potential lead of a new class of drugs for treatment of dyslipidemic type 2 diabetes.
- TET2 facilitates PPARγ agonist-mediated gene regulation and insulin sensitization in adipocytes. [Journal Article]
- MMetabolism 2018 Sep 05
- CONCLUSIONS: Our data demonstrate that TET2 works as an epigenetic regulator of Rosi-mediated insulin sensitization and transcriptional regulation in adipocytes.
- Design of PPAR-γ agonist based on algal metabolites and the endogenous ligand 15-deoxy-Δ12, 14-prostaglandin J2. [Journal Article]
- EJEur J Med Chem 2018 Aug 30; 157:1192-1201
- In a previous study, we synthesized endocyclic enone jasmonate derivatives that function as anti-inflammatory and PPAR-γ-activating entities by using key functional moieties of anti-inflammatory alga...
In a previous study, we synthesized endocyclic enone jasmonate derivatives that function as anti-inflammatory and PPAR-γ-activating entities by using key functional moieties of anti-inflammatory algal metabolites. Herein, we designed additional derivatives containing an exocyclic enone moiety that resembles the key structure of the natural PPAR-γ ligand, 15-deoxy-Δ12, 14-prostaglandin J2 (15 d-PGJ2). The exocyclic enone moiety of 15 d-PGJ2 is essential for covalent bonding with the Cys285 residue in the PPAR-γ ligand-binding domain (LBD). In silico analysis of the designed compounds indicated that they may form hydrogen bonds with key amino acid residues in the PPAR-γ LBD, and thus, secure a position in the bioactive cavity in a similar fashion as does rosiglitazone and 15 d-PGJ2. By a luciferase reporter assay on rat liver Ac2F cells, the synthesized compounds were evaluated for PPAR-γ transcriptional activity. The differential PPAR-γ transcriptional activities of the geometric and enantiomeric isomers of the selected analog were also evaluated; based on our results, the enantiopure compound (+)-(R,E)-6a1 was suggested as a potential PPAR-γ ligand.
- Dexamethasone decreases the autotaxin-lysophosphatidate-inflammatory axis in adipose tissue: implications for the metabolic syndrome and breast cancer. [Journal Article]
- FJFASEB J 2018 Sep 07; :fj201801226R
- Lysophosphatidate (LPA) signaling through 6 receptors is regulated by the balance of LPA production by autotaxin (ATX) vs. LPA degradation by lipid phosphate phosphatases (LPPs). LPA promotes an infl...
Lysophosphatidate (LPA) signaling through 6 receptors is regulated by the balance of LPA production by autotaxin (ATX) vs. LPA degradation by lipid phosphate phosphatases (LPPs). LPA promotes an inflammatory cycle by increasing the synthesis of cyclooxygenase-2 and multiple inflammatory cytokines that stimulate further ATX production. We aimed to determine whether the anti-inflammatory glucocorticoid (GC) dexamethasone (Dex) functions partly by decreasing the ATX-LPA inflammatory cycle in adipose tissue, a major site of ATX secretion. Treatment of human adipose tissue with 10-1000 nM Dex decreased ATX secretion, increased LPP1 expression, and decreased mRNA expressions of IL-6, TNF-α, peroxisome proliferator-activated receptor (PPAR)-γ, and adiponectin. Cotreatment with rosiglitazone (an insulin sensitizer), insulin, or both abolished Dex-induced decreases in ATX and adiponectin secretion, but did not reverse Dex-induced decreases in secretions of 20 inflammatory cytokines and chemokines. Dex-treated mice exhibited lower ATX activity in plasma, brain, and adipose tissue; decreased mRNA levels for LPA and sphingosine 1-phosphate (S1P) receptors in brain; and decreased plasma concentrations of LPA and S1P. Our results establish a novel mechanism for the anti-inflammatory effects of Dex through decreased signaling by the ATX-LPA-inflammatory axis. The GC action in adipose tissue has implications for the pathogenesis of insulin resistance and obesity in metabolic syndrome and breast cancer treatment.-Meng, G., Tang, X., Yang, Z., Zhao, Y., Curtis, J. M., McMullen, T. P. W., Brindley, D. N. Dexamethasone decreases the autotaxin-lysophosphatidate-inflammatory axis in adipose tissue: implications for the metabolic syndrome and breast cancer.
New Search Next
- Berberine derivative, Q8, stimulates osteogenic differentiation. [Journal Article]
- BBBiochem Biophys Res Commun 2018 Sep 26; 504(1):340-345
- Berberine has been implicated to be involved in maintaining bone health due to its anti-oxidative and osteogenic properties. However, low potency and low bioavailability limit the clinical developmen...
Berberine has been implicated to be involved in maintaining bone health due to its anti-oxidative and osteogenic properties. However, low potency and low bioavailability limit the clinical development of the drug. To overcome these obstacles, we previously synthesized a compound, Q8, which is a structural homolog of berberine. The present study examined the pharmacological functions of Q8 to evaluate its potential use in bone regeneration with respect to osteoblast differentiation. Here, we report that Q8 enhanced BMP4-induced alkaline phosphatase (ALP) activity and transcription from the ALP promoter. In addition, Q8 suppressed the expression and activity of PPARγ (a known negative regulator of osteogenesis due to its stimulatory effects on adipogenesis and its role as an adipogenic transcription factor), which in turn increases β-catenin expression in the nucleus, and ultimately promotes osteoblast differentiation. Meanwhile, Q8 reversed the inhibitory effects of the PPARγ agonist, rosiglitazone, on osteoblast differentiation. This study demonstrated that Q8 promotes osteoblast differentiation via inhibition of PPARγ and the enhancement of osteoblast function by Q8 may contribute to the prevention for osteoporosis.


text:
Vertical blinds can be fabric or blackout type – we offer both in numerous colours. Custom made Vertical blinds can be built to very large sizes and are universal, they are suitable for office and living-rooms – all depending on interior design and customer preferences. They enable easy control of light filtering into room while allowing full privacy.
Vertical blinds are one of the most frequently selected coverings for large glazed areas, which are often used in modern construction. Large window surfaces and non-standard shapes are distinguished by their modernist look. They illuminate interiors, providing continuous contact with the surroundings. Yet, they expose the rooms to a lot of sunlight and do not protect privacy. That is why it is so important to install appropriate vertical blinds. Such a solution not only guarantees proper protection from the sun rays but also protects from the sight of passers-by or neighbours. These coverings are perfect for the summer season, dominated by high temperatures. Internal vertical blinds prevent the rooms from heating up and provide a feeling of pleasant coolness in the interiors. The special design of the vertical blind allows precise adjustment of the angle of deflection of the blind and regulation of the amount of light penetrating the room.
When choosing vertical window blinds, it is worth taking into account the specifics of the place of installation and the effect we want to achieve. If we care about the maximum protection from natural and artificial light and want to minimise heating of the room, blackout vertical blinds are a good choice. It is a perfect solution for rooms facing south, bedrooms, and children’s rooms – it will ensure comfortable conditions for rest at any time of day. Fabric blinds are perfect for the living room and kitchen, where the effect of delicate light diffusion is important. Regardless of your choice, you can be sure that the vertical blind will be easy to install on the wall or ceiling and that maintenance will be simple and will save you a lot of valuable time.
Internal vertical blinds are an excellent choice for houses and flats with a modernist architectural plan and large glazed areas. You can successfully install them in bedrooms, living rooms, halls, and even in rooms that are particularly exposed to humidity and temperature changes, such as kitchens and bathrooms. By choosing the blinds made of PVC or aluminium you can be sure that they will be resistant to moisture and will not cease to impress with their impeccable appearance for many years. Made-to-measure blinds are perfect for large doors and terrace windows. Balcony vertical blinds can be easily adjusted to any space and opening system.
Vertical striped blinds are also a reliable choice for office and commercial spaces. While using them, you can protect the interior from excessive sunlight and heat, ensuring fully comfortable conditions for employees. Vertical blinds for the office are an indispensable element of any open-space type interior, where many people work simultaneously. The coverings protect computer screens from the sun rays and prevent from annoying reflections.
Vertical strip blinds are not only exceptionally functional and useful but also represent the highest aesthetic standard and designer look. From a wide range of models, materials, designs, and colours, you are sure to find a cover that will meet all your expectations. Depending on your preferences, you can opt for fabric or PVC vertical blinds. The selected coverings can be easily matched to any design style. Fabric vertical blinds in bright, subdued colours will look beautiful in classic interiors, emphasising their elegant and chic character. Blinds in a warm shade will enhance a rustic decor, while a cool colour will complement spaces decorated in the Scandinavian style. Vertical blinds in the shade of deep black will perfectly match with modern arrangements.

domain: design


Simple data exchange between tabs with the same origin
Asynchronous dynamic data at scale. Performance, data integrity, and typing for REST, proto, GraphQL, websockets and more.
Step-by-step guide to setting up and launching a TypeScript/React web app querying Ethereum blockchain data in standard querying language
A React tool to help you visualize data structure changes while you come up with an algorithm solution.
Puente React is a web dashboard used to visualize data collected on the ground in developing countries.
If you're working with REST and want an easy way to manage data fetching on the client side, this might just be the way to go.
The Geo Data Merger is an open source tool for merging data from csv, json, geo- and topojson files.
Fixed-Data-Table-2 is a continuation of facebook/fixed-data-table. The original repo is no longer maintained and has many pull requests awaiting response.
NanoSQL is a database/datastore with tons of RDBMS features, Undo/Redo, and optional built in persistence to Indexed DB, WebSQL or LocalStorage.


Snowy, windy conditions hit Southern California
Snowy, foggy weather in the Southern California mountains has closed an inland road and briefly slowed traffic on a major north-south freeway.
A low-pressure system moving through the area Monday morning could leave 3 inches of snow in some places and drop the snow level to 3,000 feet.
The National Weather Service says there's also a chance of 25 mph winds with gusts of up to 45 mph in the mountains, foothills and valleys.
Foggy weather Monday morning blinded motorists in the Interstate 5 Grapevine area north of Los Angeles. The CHP escorted cars through the mountain pass for about 10 minutes before conditions improved.
In the San Gabriel Mountains, state officials closed a 10-mile segment of State Route 2 west of Wrightwood. The annual shutdown will last through winter.


text:
UC BERKELEY AUTHOR: Karen Sokal-Gutierrez
DATE OF PUBLICATION: July 2016
REGION: El Salvador
REFERENCE: Dabiri D, Fontana M, Kapila Y, Eckert G, Sokal-Gutierrez K. Community-based assessment and intervention for early childhood caries in rural El Salvador. International Dental Journal. 2016;66(4):221-228. doi:10.1111/idj.12228.
SUMMARY/ABSTRACT: The objectives were to assess early childhood caries (ECC) in rural areas of El Salvador and to investigate the changes in caries and mouth pain in the presence of community-based interventions.


text:
Stocks rallied in early trading on Wednesday as market sentiment, which remained on tenterhooks for last two months in the backdrop of policy logjam in Washington due to issue of tax increases and spending cuts, was boosted immensely after lawmakers finally cleared the bill that averts the fiscal cliff even as some other budget issues such as long-term spending cuts remain unresolved.
Late on Tuesday night, the House of Representatives, dominated by Republicans, cleared the bill, which would raise taxes on individuals having an annual income above $400,000 or $450,000 for couples to 39.6 percent from 35 percent, a demand made by President Obama ever since he started his reelection campaign. The bill now needs President Obama’s sign in order to become a law.
Meanwhile hosts of other issues such as long-term spending cuts, and debt ceiling limit (which is technically over but accounting adjustment has enabled the government to continue with its normal functions for two more months), will keep investors slightly edgy in coming weeks.
In some corporate news, shares of Zipcar Inc. (NASDAQ: ZIP) rallied after larger rival Avis Budget Group Inc. (NASDAQ: CAR) announced that it agreed to acquire Zipcar in an all cash deal, valued at $500 million or $12.5 per share, representing a premium of 49 percent on ZIP’s closing value on December 31st 2012.
Shares of social networking giant, Facebook Inc. (NASDAQ: FB) gained after JP Morgan boosted its price target on FB stock to $35 from $29
Elsewhere in Europe, the Pan European Stoxx 600 was gaining 2.01% Index, FTSE 100 was up 2.38%, Germany’s DAX was climbing 2.03% while Spain’s Ibex 35 jumping 1.95%
More Posts by this author
- Stocks End Higher
- Gold Prices Settle Lower; Silver Prices also Slip
- U.S. Stocks Struggle for Direction as Investors Eye Bernanke’s Testimony
- Stocks Edge Higher in Early Trading
- Forex Market Update: Dollar Bounces Back, All Eyes on the Fed
- Gold Prices Fall, Silver Prices Down as Well
- Stock Futures Slip
Post Written By: Ed Liston
Ed Liston is a senior contributing editor at TheStockMarketWatch.com. An active market watcher and investor, Ed guides an independent team of experienced analysts and writes for multiple stock trader publications. He is widely quoted in various financial publications on the Internet. When Ed is not writing about stocks, investing in stocks, talking about stocks, or otherwise doing something stock related, he likes to go sailing and fishing in his yacht.