The pianist Sabine Sauer has a long-standing friendship with Jean-Pierre Leguay. In December 2014, he sent her the edition of the piano cycle Allume l'aube dans la source, published the same year. Fascinated by the way Leguay exploits the sound pos-sibilities of the piano, she began to take a close interest in his music. In 2015 and 2016, she had already included some pieces from the cycle in her concert programme. In 2017, she organised a portrait concert as part of the Musik am 13. series in Bad Cannstatt, during which Leguay himself improvised on the organ and where she gave the German premiere of further parts of Allume l'aube dans la source. In 2020, the year of the premiere of Envol, the idea matured to record all piano works com-posed by Leguay that had not yet been recorded. Inspired by their fruitful collaboration, Jean-Pierre Leguay composed the new piano piece Momenti in the summer of 2022, which is dedicated to her. All recordings of this edition took place in the library hall of the Ochsenhausen monastery in the presence of the composer.


text:
For this assignment the theme selected was chess pieces. The reason for this is chess pieces look good and a Lego rendition of medieval executions is too depressing. Maybe later…
The first couple of shots for this one came out really over exposed but it honestly worked. They kinda had a fae vibe which works for wizardy magic stuff.
And here is the lighting setup made in a lighting setup thing that really couldn’t represent what was going on perfectly but oh well.
Apparently you can use almost anything as a reflector. Books, especially big tome looking books are great reflectors.

domain: hobby


text:
The Center for Bioethics and Research is at it again! In partnership with Collaborative Institutional Training Initiative (CITI), we are pleased to announce a new Healthcare Ethics Committee (HEC) course.
HEC course addresses basic healthcare ethics committee attributes including general mission, varying structures, membership, roles, responsibilities, and functions of HECs and case consultants.
Healthcare Ethics Committees (HECs) are faced with many common issues including informed consent, advance directives, end-of-life issues, medical confidentiality, neonatal and maternal-fetal ethics, decision making for capacitated and incapacitated patients and allocation. Thus, HEC members need to be grounded in the application of knowledge of ethical theories, principles, and arguments to identify, analyze and resolve these ethical issues in healthcare settings. This course will enable Health Ethics Committee (HEC) members, healthcare administrators and healthcare professionals to be aware of core ethical principles and applications in healthcare settings, and their duties to others.
Click here to get started and to take advantage of this and other course offerings including Informed Consent, Good Clinical Practice, Essentials of Research Administration, Biosafety and Conflict of Interest.

domain: medical


Go Radio - Lucky Street
Release Date: March 1st 2011 (Fearless Records)
Go Radio’s eagerly anticipated debut full-length, Lucky Street, effortlessly manages to showcase captivating musical elements as well as exceptionally breathtaking vocal performances throughout the entirety of the album’s thirteen track duration. However, for more than the sake of a brief background history, it was a lot of sustained effort to currently arrive at this point. In 2008, the band self published and released their debut EP titled Welcome To Life which amassed quite the critical reception and widespread appeal amongst much of the general public - such positivity didn’t go unnoticed from record labels and Fearless soon signed the talented Tallahassee quartet. Subsequently, a sophomore extended play, Do Overs and Second Chances was released in April of 2010 that showcased slightly more glisten, sparkle and polish that entwined sensationally with the abundance of infectious hooks and inimitable melodies the band offered. If you’re one of those who are currently awaiting Lucky Street with a sense of palpable anticipation and expectation; you should also begin preparing for Go Radio to convincingly surpass them all.
First single and album opener “Lucky Street” begins with the intrusive sound of emergency sirens and frenetic traffic on an overpopulated street which is somewhat ironic given the album title. It isn’t long thereafter that cascading drums, luscious guitar tones and the unmistakable rawness of Jason Lancaster’s vocals are shown the spotlight and refuse to leave. It’s an accessibly solid opener that admittedly plays it safe and stays firmly entrenched within the confines of its comfort zone. The lyrics are meaningful and compelling, but more importantly they’re also open to broad lyrical exploration. With lines such as “Everybody falls and then sways as if to beats/ except for you and me, we’ve got promises to keep here on Lucky Street”. It’s apparent that it’s a relatable tune of vulnerability and regret for as the beats change around you, so do those that listen until nobody is ever the same as we previously remembered them. “Singing With The King” features a soaring chorus that combines splendidly with enticing dual layered vocal melodies to capture a bouncy, energetic and memorable feeling. The vocals are delivered with such emphatic precision and whilst it’s simplistic in overall structure, like a tapestry, its inner melodies and secrets are revealed after those first few initial listens. It’s another step nearer to the pop/punk brilliance this band look to be increasingly capable of delivering.
Although it may not be an instant favourite upon first impressions, “Strength To Stay” showcases a distinct change in vocal delivery within the uniqueness of its chorus. Lancaster puts a noticeable amount of strain and tension on his voice resulting in a higher pitch than he has ever previously experimented with on any prior record. The third and final verse is sensational as vocals soar with intense momentum and passion over a background of wonderful instrumentation from the remaining members of the band which results in a sense of restrained euphoria as Lancaster shouts, “You can’t find the nerve when all you want is to breathe/can we save you?”. Beautifully prominent piano chords signal the opening to “Swear It Like You Mean It” and it isn’t long before it’s evident that the track will be rendered unforgettable in the context of Lucky Street. Lancaster sounds exceptional and the song itself resembles something that could have been located on the band’s previous extended play, Do Overs and Second Chances such is the enormity of its glorious verses and stunning chorus.
To this point, its all been quite overwhelmingly positive but it must also be noted that there are several missteps and negatives that need to be both taken into account and discussed. When it was announced that both “Why I’m Home” and “Forever My Father” would be re-recorded and subsequently included onto the official track list, I immediately had misgivings. How could anything compete with the heart wrenching rawness and intricate emotion of “Forever My Father” when the original is already superb? How could Lancaster’s vocals be anymore vulnerable, beautiful and saturated in sincerity than they are in “Why I’m Home”? How can re-recorded versions of two immeasurably powerful songs possibly compare to their originals in any facet? Quite simply, they don’t. The emotion is lackluster and it all feels too polished which is best exemplified in a cinematic, orchestral feel midway through “Forever My Father.
“Fight, Fight (Reach For The Sky) features a welcoming trumpet that’s prominent throughout the numerous verses the track contains. It’s an energetic, pulsating pop/punk tune with a gigantic chorus and aggressively raw vocals. The aforementioned song is a resounding contrast to the delicate and delightful ballad, “House Of Hallways” which features gentle guitar picking, irresistible vocal harmonies and uncompromising passion. The power behind the track is in its ability to artistically paint vivid imagery with every individual lyric sung. As Lancaster sings with his voice trembling ever so slightly, “I swear that there’s someone who cares here enough to set us free/And if the world don’t turn just enough to bring her honest/then I guess we’re better off forgotten”, you can hear traces of vulnerability and insecurity throughout its contemplative duration. “The Truth Is” concludes the album in romantic and heartfelt style with lyrics of unwavering optimism, adoration and love in it’s most powerful of forms. With lines such as “Cause I’ve had dreams where we collected all the clocks and put them all to bed/Because here inside this moment there is us/There need be nothing else” it’s undoubtedly clear that Lancaster has the ability to write relatable lyrical content that is both expressive and sincere.
Lucky Street is available for purchase on March 1st via Fearless Records.
- indieoriented posted this


text:
The New Yorker's Alex Koppelman flags an interview Mitt Romney gave to the Salt Lake Tribune in February 1999:
"I have been involved with companies that concluded they had to close a plant in order to survive. And that's an awful, awful thing to have happen. And it's death for a politician to be associated with that."
Koppelman has the full quote here.

domain: politics


text:
Choosi Choodangane is a coming of age rom-com story about a photographer Siddu (Shiva Kandukuri) who meets and falls in love with musician Shruthi (Varsha Bollama) after a painful break-up in his college days with Aishwarya (Malavika). The rest of the story is about how Siddu-Shruthi’s love propels towards a happy ending with twists.
Watch Telugu Full Movies Here:
Movie Details – Choosi Choodangaane
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domain: entertainment


text:
The public relations officer said that the new political administration, which came to power on 17 September, had replaced Rogers for "no specific reason".
Local news sources said that both Rogers and his deputy, Mohamed Fofanah - who has also left - were seen as "pro
- James Bullard on 2% rates, tariffs and Fed leadership
- Turkish central bank raises overnight rates in bid to stop lira’s fall
- Podcast: David Hendry and John Muellbauer on empirical macro
- Policies must change to stop emerging markets crisis, analysts say
- Next financial crisis “will be brewing” in shadow banking – Bullard

domain: economics


text:
Tuesday could be a good day in the district as the results of surveys with current and former parents, students and staff members are released and reviewed by the board of trustees.
"We haven't seen the survey results yet, but we are looking forward to finding out what the public has had to say," Jan Johnstone, vice-chairwoman of the Bluewater District School Board of trustees, said yesterday.I'm curious as well, and will try and make a point of posting Canton's update as soon as the news alert crosses my desk and I have a spare moment. To my knowledge -- and please correct me if I'm wrong -- the BDSB is the only one to have conducted this type of survey. It could say a lot, or very little, about perceptions of the board within the communities it serves.
"I honestly don't think there'll be any surprise, but rather the results will provide us with an opportunity to again move forward. This is something we need to do annually, take the pulse of our community."

domain: news


text:
- Front Porch
SOUTHINGTON — The Town Council unanimously approved a $13 million energy efficiency plan Monday that councilors say will be paid for by energy savings over the next 14 years.
The council’s six Republicans councilors approved the contract with Noresco and a loan from Bank of America. All three Democratic councilors were absent. Noresco will oversee the plan.
Work will be done at municipal and Board of Education buildings as well as on streetlights, which will be changed to LED lights. Projects range from added insulation and weather stripping to replacing heating and cooling systems at the high school.
Town Manager Garry Brumback said overall the projects pay for themselves in less than 15 years. Some of the individual projects have shorter timeframes while others, such as the heating and cooling system replacements, will take as long as 60 years to recoup costs.
John Kauppinen, Noresco senior account executive, said the energy cost savings are guaranteed. At first, those savings pay for the cost of the upgrades but after payoff they reduce the town’s utility bills.
“After the contract you reap the financial benefits of the continued savings,” Kauppinen said.
Councilor Stephanie Urillo questioned whether more efficient technologies might reduce the payback time of the some of the work.
Brumback said that projects that are quickly paid off help generate savings that will fund more expensive improvements.
“All put together, some of the shorter-term paybacks help pay for some of the longer-term paybacks,” he said.
Assistant Town Engineer Annette Turnquist said work is scheduled to begin this summer. Improvements to schools will be completed during summer break.
“We’ll have a few things going on simultaneously,” she said.
Work will likely be completed next spring, according to Kauppinen.
“We are taking energy conservation very, very seriously in town,” said Council Chairman Michael Riccio.
The town received a 2.9 percent loan from Bank of America for the improvements.
Throwback Thursday: A different Route 5 in Wallingford …
A lot has changed in just 21 years at the base of Dead Man’s Hill in Wallingford. Heading south out of Meriden and into Wallingford … more ...
Southington police identify man found dead on Copper Ridge …
SOUTHINGTON — Police identified a man found dead at the bottom of a cliff near Copper Ridge Saturday as Eric Alberti, a former Southington resident … more ...
Two face charges after police find drugs in Wallingford traffic …
WALLINGFORD — Two Massachusetts residents face charges after police say heroin, prescription pills and marijuana were found during a traffic stop. James Richards, 36, of … more ...
FARLEY’S 50, PT. 1: Where it all began for Wallingford’s …
Editor’s note: This spring will mark Charles Farley’s 50th year of coaching in the Wallingford school system, most of it at Sheehan, most of it … more ...
Emergency crews respond to four-car crash in Wallingford …
WALLINGFORD — Emergency crews are responding after four vehicles were involved in a crash on North Colony Road Monday evening. Only minor injuries were reported … more ...


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A personalised book like no other. Wonderfully written and illustrated, every name creates a different story. With over 1 million books sold in more than 165 countries, it's the perfect gift for children and babies aged 0 to 6 years. Create yours today.
It's the new winter floral cloud blanket! Pictured here with our winter floral boppy cover, solid coral crib sheet, coral chevron changing pad cover, pink kilim crib sheet, and coral watercolor dots changing pad cover.

domain: literature


text: Soggy Doggy by Spin Master. Soggy Doggy is the showering, shaking, doggy bathing game for kids and the whole family. Players roll the die and move their playing pieces around the game board, taking turns washing Soggy Doggy. But watch out! You never know when he will shake to dry off and you'll get a little wet!. Play Dog Games on jadibd.co If you like dogs you will surely know scooby doo and other dog heroes in games like Cat vs Dog, Pet soccer and puppy dressup. Pick one and play online. Puppies, dogs, and games! What could be better? Play games featuring adorable and playful pups, on Disney LOL and raise the WOOF!.

domain: game


text:
The men range range in age from 25 to 59 years old, while the alleged prostitutes ranged in age from Prostitutes Warren those arrested was a State Farm insurance agent, an OnStar technician, a Bank of America employee and a student from East Lansing, according to authorities. WXYZ — Prostitutes Warren police have arrested 46 people in connection to a human trafficking and prostitution sting in the city.
Phase one culminated with 35 arrests back in May. Among those arrested was a State Farm Prostitutes Warren agent, an OnStar technician, a Bank Prostitutes Warren America employee and a Prostitutes Warren from East Lansing, according to authorities.
We're told if evidence shows they're victims of sex trafficking the charges will be dropped. Among the nearly Prostitutes Warren people arrested for human trafficking in Warren Friday morning were a student and bank employee. Over the two operations there have been a total of arrests, Prostitutes Warren felony and misdemeanor charges so far.
I am disappointed in Sen.
Warren police say they have relationships with various hotels Prostitutes Warren that they were forthcoming and helpful in the latest Prostitutes Warren operations. On Friday, police Prostitutes Warren 31 felonies and 72 misdemeanors have been handed down from phase two of the operation. The 46 people taken into custody Prostitutes Warren in age from 25 to 60 years old, Dwyer said. We have young people again forced into prostitution and drug addiction.
Warren police arrested 25 women and 21 men during a three day sweep and charged them with a total of crimes, Commissioner Bill Dwyer said.
Prostitutes Warren charged them with a just click for source Prostitutes Warren 30 felonies and 45 misdemeanors. The players are not just from Metro Detroit but came from as far away as East Lansing. It's the second time this year. Would you like to receive local news notifications on your Prostitutes Prostitutes Warren
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Warren police arrest 46 in Prostitutes Warren trafficking sting Among the nearly 50 people arrested for human trafficking in Warren Friday morning were a student and bank employee. Dwyer said that in the first sting, they were able to identify three victims of human trafficking. They're asking anyone Prostitutes Warren may know anything about human trafficking or prostitution to call Warren police.
Local time America/Detroit
Prostitution, drug sting leads to 46 arrests in Warren
Warren (Uorun, Voren, warn mshy gn, Warren, woleon, Uorren, wwrn)
46 arrested in Warren as part of multi-phase human trafficking sting

domain: law


Items of note that you can see in this picture of my Rep(St)rap:
- I used the BitsFromBytes laser cut plastic with alloy screws and other hardware I bought from McMaster.com and Fastener-Express.com.
- I decided to mount all of the electronics on a thin 8×10 acrylic plate ($1.58 at Lowe’s) to make power distribution easy and to retain an appearance similar to the rest of the machine.
- Everything is there but the heater. I’m still waiting for the nichrome wire to arrive. I can be patient, so I used free super saver shipping. 🙂
- I used aluminum gears in place of the plastic ones because the aluminum gears have the same pitch (distance between teeth) as the belts. Until I did this, the belts slipped a lot, but now it’s actually kind of hard to make them slip.
- The Z belt tensioner uses an M8 rod instead of an M8 screw. It extends to the bottom of the cage, giving the tensioner extra stability.


text:
From screen to print, The Bold and the Beautiful collaborates with Pan Macmillan to give fan fiction a whole new meaning. The anticipated eight-book romance series places B&B characters in alternative stories that have yet to be attempted on-screen.
The series is a part of the digital-first imprint Momentum, and each story pairs unlikely characters in spectacular situations. Fans longing for a Steffy Forrester and Bill Spencer reunion or wondering about a Bill Spencer and Taylor Hayes connection might be intrigued by the novellas.
In book one, Forbidden Affair, Steffy and Bill's passions reignite when the two are trapped together beneath the rubble of a Los Angeles earthquake. Collision Course, book two, sends Taylor on a psychological journey with Bill Spencer, who's hiding severe posttraumatic stress disorder that he developed upon surviving a plane crash.
The Sydney Morning Harold relays that it could be the first time a soap opera has transitioned to a romance series. The collaborators hope for a large transitioning market to go with it, and it just might happen as long as the stories are true to the show's past without confusing the show's present and future.
According to CBS, Brad Bell stated that the Bold and Beautiful partnered with Pan MacMillian to give the fans more storyline choices for the soap's signature characters. "Love stories that have yet to be seen on television can now fully ignite between the covers of these novels," Bell stated on the CBS blog.
Fans can look forward to two more titles in April. Second Chances involves Rick Forrester and Steffy bonding over their suppressed grief about Phoebe's death, and Stormswept showcases a resurgence of the Hope Logan and Oliver Jones romance.
The romance novels will debut as e-books worldwide at a time when B&B approaches its 7,000th episode. In Australia, viewers can also pick up paperback editions beginning January 28, 2014.
Which of The Bold and the Beautiful books are you most looking forward to? We want to hear from you -- and there are many ways you can share your thoughts.


text:
STOP HURTING. START LIVING.
We are an established Acupuncture clinic serving the Greater Gainesville, Florida area. We specialize in the following difficult to treat conditions:
Low back pain and sciatica
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New Leaks to the upcoming RTX-4000 cards have appeared – and they have it in themselves! According to the rumor kitchen, the upcoming graphics card generation of NVIDIA will be damn fast, but PC players have to swallow a bitter pill.
- RTX 4000: NVIDIA GPUs are likely to consume massive electricity
- AMD graphics cards will also consume more
In the rumor kitchen it breaks again. Lately, there have been increasingly new rumors to the GeForce RTX-4000 models, which according to a well-known leakers should go to the start in September 2022 (Source: Twitter / Greymon55).
The hardware leaker Greymon55 has already been correct in the past with its predictions of the more often, but one should consider the assumptions with caution. Greymon55 also assumes that the RTX 4000, probably the GeForce RTX 4090, is about 2.5 times as fast as the RTX 3090 **. That would be a immense performance growth. Finally, the current flagship offers enough power to portray even sophisticated games in 4K fluid.
But these performance jumpers seem to buy expensive ones. For both Greymon55 and Kopite7kimi, another well-known hardware leaker, have heard rumors that say that the new high-end maps become real power-eaters.
The RTX 4080 should consume under load up to 450 watts (without cooling and lighting), at which RTX 4080 Ti should already be 650 watts and at the RTX 4090 even incomprehensible 850 watts .
For comparison: The TDP of RTX 3090 Founders Edition is including cooling and lighting at 350 watts. So it seems like NVIDIA would purchase the performance thrust through an immense increase in power consumption – and that should be clearly noticeable in the calculations of the PC players . We press the thumb up that the consumption of the new graphics cards in the end are clearly below the values from the leaks.
_Original article: _
RTX 4000: NVIDIA GPUs are likely to consume massive electricity
If you just want to buy a new graphics card, you have to grab deep into your pocket. The prices have been rising again for a few months – and that, although in the fall of 2022 the next GPU generation is in front of the door.
Currently, details about RTX 4000 and RX 7000 are still rar sown, but the well-known hardware leaker Greymon55 has now found an interesting information about Nvidia’s next flagship, the GeForce RTX 4090 . It assumes that the top GPU is reached a real power-eater and reaches a TDP of 550 watts . For comparison: The current top model, the RTX 3090, has a TDP of 350 watts, the consumption of the 2080 ti was at that time at 250 watts.
If the guess of Greymon55 turns out to be true, some PC players should encounter properly in front of their heads. For such a high power consumption, the difference at the end of the year would be clearly noticeable on the electricity bill **.
In addition, it must not be forgotten that heat development would increase due to the increased power consumption. In other words: The graphics card will be much harder to cool and could heat up your premises in the summer.
_ And what else is important in the gaming and technology world happens? We reveal it to you in the rumor kitchen Insights: _
AMD graphics cards will also consume more
But not only the new NVIDIA graphics cards could be genuine energy in the upcoming generation. Greymon55 assumes that could also land AMD’s top models at a TDP of about 500 watts . For many PC players, a change of the power supply should be necessary at the latest.
Nvidia’s new graphics card is twice as expensive as the RTX 3090
But until the time has come, it takes a while. Currently one goes out of it that NVIDIAS RTX-4000 graphics cards go to the start in October 2022 , AMD’s new models should then be in the stores in the early 2023. Whether the new GPUs can then be available for the EIA, or thanks to the chip crisis and the scalper the prices are back to the height, remains to be seen.


Match ends, Luton Town 2, Port Vale 0.
Luton heaped further misery on Port Vale manager Michael Brown with a comfortable win at Kenilworth Road.
Defeat for the visitors meant they have now lost six league matches in a row, and the Valiants have also gone five games without a goal.
The Hatters wasted a glorious chance on 12 minutes, Andrew Shinnie heading woefully wide from close range.
Town had the lead on 38 minutes though due to a calamitous own goal from Ben Whitfield, who diverted Luke Berry's pass beyond his own goalkeeper from 15 yards.
Whitfield then sent a volley over at the other end, before Anthony de Freitas' free-kick required a fine save from Marek Stech.
Town extended their advantage on 50 minutes as Jack Stacey ran 60 yards before hammering into the roof of the net.
David Worrall's 35-yard effort did not miss by much, while Pelly-Ruddock Mpanzu's blast was parried by Vale keeper Sam Hornby.
Shinnie fired into the side-netting for Luton, with Stech tipping over De Freitas' header, the keeper then making a brilliant stop from Worrall late on to preserve his clean sheet.
Match report provided by the Press Association.
- 4McCormackBooked at 66mins
- 11ShinnieSubstituted forCornickat 84'minutes
- 19CollinsSubstituted forLeeat 90+1'minutes
- 5DavisSubstituted forPykeat 84'minutes
- 35MiddletonBooked at 54minsSubstituted forStobbsat 73'minutes
- 28de Freitas
- 14BarnettSubstituted forTurnerat 62'minutes
- David Webb
- Shots on Target
Second Half ends, Luton Town 2, Port Vale 0.
Delay over. They are ready to continue.
Substitution, Luton Town. Elliot Lee replaces James Collins.
Danny Hylton (Luton Town) wins a free kick in the defensive half.
Foul by Gavin Gunning (Port Vale).
Attempt missed. Luke Berry (Luton Town) right footed shot from outside the box is too high.
Foul by David Worrall (Port Vale).
Pelly-Ruddock Mpanzu (Luton Town) wins a free kick in the attacking half.
Attempt missed. Dan Turner (Port Vale) right footed shot from a difficult angle and long range on the right misses to the left.
Substitution, Luton Town. Harry Cornick replaces Andrew Shinnie.
Substitution, Port Vale. Rekeil Pyke replaces Joe Davis.
Joe Davis (Port Vale) wins a free kick on the right wing.
Foul by Andrew Shinnie (Luton Town).
Foul by Tom Anderson (Port Vale).
Alan Sheehan (Luton Town) wins a free kick on the right wing.
Attempt missed. Luke Berry (Luton Town) right footed shot from outside the box misses to the left.
Corner, Port Vale. Conceded by Glen Rea.
Substitution, Port Vale. Jack Stobbs replaces Harry Middleton.
Corner, Port Vale. Conceded by Marek Stech.


With the development of modern electronic technology, the development of interface technology has become more and more rapid, and the USB interface has developed and expanded in this context. In traditional hardware architectures, interfaces are considered to be part of the corresponding external device, and each interface can only be connected to the same device. Although several devices of the same type can be connected to the same interface through the so-called â€œdaisyohainâ€ method, different types of devices cannot be connected to the same interface. Since the devices of the USB interface are more and more abundant, the types are more and more The more you come in, to meet this demand, here is a USB 2.0 interface solution that reads various USB devices through the USB interface; reads various mainstream memory cards through the SD card interface. The solution supports commonly used USB storage devices (including USB flash drive / USB hard drive / USB flash drive / USB card reader) and SD card (including standard capacity SD card and high capacity HC-SD card and protocol compatible MMC card and TF card) ). This paper proposes a smart multi-interface full hardware audio system solution, which further enhances the scalability of the audio system. In principle, it can connect most of the current mainstream storage devices and realize the expansion of one device for multiple purposes. It can further improve the utilization rate of existing resources, has certain economic and social benefits, and adopts power control methods such as full hardware decoding and single-chip frequency reduction work, so that the power consumption of the whole system is reduced to about 50% of traditional similar devices. , in line with the theme of China's energy conservation and environmental protection.
l hardware system design
1.1 Chip Overview
ATmega128 is a low power 8-bit CMOS microcontroller based on an enhanced AVR RISC architecture. Due to its advanced instruction set and single clock cycle instruction execution time, the ATmega128 has a data throughput rate of up to 1 MIPS/MHz. The AVR core has a rich instruction set and 32 general purpose working registers. All registers are directly connected to the arithmetic logic unit (ALU), allowing one instruction to simultaneously access two independent registers in one clock cycle. This architecture greatly increases code efficiency and has up to 10 times the data throughput rate compared to conventional CISC microcontrollers.
CH376S is a file management control chip for reading and writing files in a USB flash drive or SD card. CH376S supports USB device mode and USB host mode, and has built-in basic firmware of USB communication protocol, firmware for handling special communication protocol of Mass-Storage mass storage device; communication interface firmware of SD card and management of FAT16, FAT32 and FAT12 file system The firmware supports commonly used USB storage devices and SD cards.
The VS1053B is a single-chip Ogg Vorbis/MP3/AAC/WMA/MIDI audio decoder and IMA ADPCM/user-loadable Ogg Vorbis audio encoder. It supports CD-level audio playback and recording. The chip contains a high performance and low internal. The DSP processor core VS_DSP consumes 16 KB of instruction RAM and 0.5 KB of data RAM. The VS1053B has a serial control and data input/output interface, eight GPIO interfaces, a high performance variable sample rate DAC and ADC, a stereo audio input interface and a stereo audio output interface. PL2303 is used to convert USB to standard RS 232 serial port, 2 independent large buffers for 2 bus connections, large data buffer for USB bulk data transfer, and automatic handshake mode for serial communication Therefore, it can reach a baud rate much larger than the standard UART controller. The PL2303 supports USB power management and remote wake-up protocols. In this design, the PL2303 chip is mainly used to combine the download line and the power supply module of the main control unit into one, which greatly simplifies the design complexity of the system. The NOKIA 5110 liquid crystal display is a traditional dot matrix liquid crystal display, and does not have built-in English and Chinese character font, so in the process of NOKIA 5110 liquid crystal display, the MCU needs to convert the ASCII code value read from the memory into the corresponding English and Chinese dot matrix information, and then transmit the dot matrix information to the liquid crystal display through the serial port. display.
1.2 hardware design block diagram
The hardware system is mainly composed of a main control module, a smart expansion interface, an audio codec module, a liquid crystal display module, a keyboard LED indication module, and a JTAG/ISP/RS 232 download interface, and the logical connection diagram is as shown in FIG.
1.3 interface design
1.3.1 VS1053B and keyboard and LCD interface design
The corresponding functions of the keyboard control unit of KEY1 to KEY7 are shown in Table 1. LED1~LED7 correspond to the button indicator, such as button KEY1 is pressed. Then the LED1 light is on. The peripheral interface is shown in Figure 2.
1.3.2 USB host device interface design
The interface design of the USB host device is shown in Figure 3.
This article refers to the address: http://
The system software design mainly includes the main program, the interrupt control subroutine, the keyboard scanning subroutine, the LCD control subroutine, and the peripheral module control program. The main program running process is shown in Figure 4, and the software system flow chart is shown in Figure 5.
2 software system design
The entire design operation is shown in Figure 6 and Figure 7.
Through this design, the control function of the single-chip microcomputer in the intelligent multi-interface design is further enhanced, and the processing method in the case of multiple interruptions. In the MCU application system, the function of man-machine dialogue is usually required, and the data can be input at any time, and various corresponding control commands are issued, and finally the operation result is output to the LCD display through the output interface. Since the LCD display of the design belongs to the traditional liquid crystal display and does not have any fonts built in, it is necessary to read the Chinese character dot matrix information in the SD card Fat file system through the single chip microcomputer, convert the ASCII into the corresponding dot matrix information, and then display it. Further increasing the difficulty of system control.
Since the system can reuse the existing resources, the solution using the intelligent interface can flexibly read and write various storage devices, thereby further improving the utilization of resources, so the system has certain social value and Prospects.
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Rectangular Sensor Automatic Dustbin
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Rodney Earwood and Palmer Cray had been best friends for as long as either could remember. They were brothers in all but the genetic sense, each born late in the lives of good women who had given up on the dream of motherhood by the time their respective miracles occurred. They wandered the hills of North Georgia, hunted the pine woods, fished the cool, green streams, and camped under the stars. They shared each other's clothing, each other's families, and each other's homes. They grew into tall young men, and on a hot May afternoon right after they turned eighteen, they both graduated from Sweetwater High School, numbers seven and eight in the crooked, sweaty line that held a class of thirty of Sweetwater's finest. Shortly thereafter, Rodney and Palmer flew a Camaro into a tree, Palmer flew into a haystack, Rodney flew into the great beyond, and nothing in Sweetwater was ever the same again. Follow Palmer in the aftermath of his one great mistake as he confronts regret at his own fallibility, endures punishment for his actions, finds unexpected redemption in unusual places, and is given a second chance to try to make it all right. He is joined in this journey by an unlikely cast of associate--including a methamphetamine dealer named Cheddar, a junkyard owner named Ottis Lee, a coffee-can addict named Bay-Annette, and an Alzheimer's patient who was once Rodney's mother--as they face each day and try to overcome their Sweetwater Blues.
Similar books by other authors
Used availability for Raymond L Atkins's Sweetwater Blues
September 2014 : USA Paperback
September 2014 : USA, Canada, UK Kindle edition

domain: library


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Elaine & David chose the stunning setting of Dundas Castle for their wedding venue. The ceremony took place in the ‘Auld Keep’ with the ceremony held in the Pavilion Marquee on the beautiful lawns of the estate.
Elaine held a compact hand tie of off-white akito roses with the bridesmaids holding similar but smaller versions.
For the ceremony The Auld Keep was decorated throughout with lots of different heights of candles in glass. The dinner reception tables in the Pavilion were decorated with a tall lily vase with white cala lilies and greenery with little pots of flowers to match and tea light candles.

domain: design


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Fairy Coloring Book 11 14686 Special Casual 6, Fairy Coloring: Coloring
The amusing Fairy Coloring Book 11 14686 Special Casual 6 picture above, is one of the few amusing sketches that associated to Fairy Coloring editorial, which is sorted within Coloring. Published by with total 14 sketches, at April 18th, 2019 11:01:18 AM.
Tagged as fairy coloring page free object as well as fairy coloring pages online subject with fairy coloring pages pdf topic also fairy coloring books object plus unicorn fairy coloring page topic along with fairy coloring pages for adults discussion and Coloring, please don’t forget to check out the main article in Fairy Coloring.
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It has been thought the oldest of the wisdom sutras is the Astasahasrika Prajnaparamita Sutra, also called The Perfection of Wisdom in 8, The best-known work from this period is the Astasahasrika Prajnaparamita (Eight Thousand-Verse Prajnaparamita). The first Chinese translation appeared in. A palm-leaf manuscripts containing Rāhulabhadra ‘s Prajñāpāramitāstotra and the Aṣṭasāhasrikā Prajñāpāramitā. The ‘Perfection of Wisdom in Eight.
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Views View Edit History. The work of art itself is in the public domain for the following reason: Multi-license copyright tags for more information. This file has been identified as being free of known restrictions under copyright law, including all related and neighboring rights. This image may not be in the public domain in these countries, which moreover do not implement the rule of the shorter term. They also supplement their philosophical austerity with the personally appealing figures of mythology.
As Subhuti in the line PP sutra states:. She is usually represented yellow or white in colour, with one head prajnaparamit two arms sometimes morethe hands in the teaching gesture dharmachakra-mudra or holding a lotus and the sacred book.
This image may not be in the public domain in these countries, which moreover do not implement the rule of the shorter term.
I have begun, obviously, with the Edward Conze astasahasrlka, but there seems to be too few sources for its history and alternative renderings. It has been replaced with a later palm-leaf folio without miniatures and in a different script. This is a file from the Wikimedia Commons. Views Read Edit View history. Note that a few countries have copyright terms longer than astasahsarika years: A good friend kalyanamitra is useful in the path to fearlessness.
Sanskrit Manuscripts : Prajñāpāramitāstotra, Aṣṭasāhasrikā Prajñāpāramitā
The first Chinese translation appeared in ce. Perspectives on Huayan Buddhism. The depiction of Prajnaparamita as a Yidam deity can also be found in ancient Java and Cambodian art.
In the Prajnaparamita texts, prajna wisdoman aspect of the original Eightfold Pathhas become the supreme paramita perfection and the primary prajnapramita to nirvana.
Learn More in these related Britannica articles: This file has been identified as being free of known restrictions under copyright law, including all related and neighboring rights.
Also frequently associated with her are a rosary, sword to cleave away ignorancethunderbolt vajrasymbolizing the emptiness of the voidor begging bowl renunciation of material goods being a prerequisite to the obtaining of wisdom.
Both have been translated into many languages and have often been praajnaparamita upon. This is a faithful photographic reproduction of a two-dimensional, public domain work of art.
This is possibly the teaching of Buddha. Any text you add should be original, not copied from other prajnaparamitw.
This page was last edited on 23 Decemberat According to Paul Williams, another major theme of the PP sutras is “the phenomenon of laudatory astasahaarika reference — the lengthy praise of the sutra itself, the immense merits to be obtained from treating even a verse of it with reverence, and the nasty penalties which will accrue in accordance with karma to those who denigrate the scripture.
Thank you for your feedback.
Prajnaparamita – Wikipedia
He was the first pope…. This photographic reproduction is therefore also considered to be in the public domain in the United States. I just picked up ‘Indian Buddhism’ by Warder, for an overview astasahadrika early Buddhism up to that time.
Dharmamitra Heng Shou’s translations: Item Metadata No Metadata Available. The lengths specified by the titles are given below.
My reason for sharing this with you is in the hope that some of you out there might be able to share any suggestions to for study. The Chinese traveler Faxian described images of the personified Prajnaparamita in India as early as cebut all known existent images date from or later. From Wikipedia, the free encyclopedia.
From Wikipedia, the free encyclopedia. I read some thing about three levels of metta that were set out in this great work of Nagarjuna. After a suite of dreams prajnaparamiita his decision, Xuanzang determined to render an unabridged, complete volume, faithful to the original of fascicles. Retrieved from ” https: Multi-license copyright tags for more information.
The PP sutras state that dharmas should not be conceptualized either as existent, nor as non existent, and use prajjnaparamita to highlight this: Bodhisattvas also have no pride or self-conception rpajnaparamita manyeta of their own stature as Bodhisattvas. Public domain Public domain false false This work is in the public domain in its country of origin and other countries and areas where the copyright term is the author’s life plus 70 years or less.


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How long do you think it takes to break a habit? Three weeks? Forty-one days? Three months? Six months?
I’ve read lots of different numbers. In my experience, there is no hard and fast rule. It depends on a lot of things. Rather than in terms of the number of days or weeks, I like thinking about it as what I’ve heard is the approach of the Zen masters: Line in water, line in sand, line in rock.
If you draw a line across water, it will disappear quickly. Those things we do that we can stop doing with no effort aren’t habits at all. They are like making lines in water.
Now think about making a line in the sand at the beach. The line doesn’t disappear until a wave or two washes over it, but then it goes away quickly. Some habits are like that. They are easy to break. Usually, they’re habits that aren’t very important to us, or that we haven’t been doing very long.
Then there are the habits that we’ve had for a long time and that are very challenging to break. They are like lines in rock. Think about that. If you carve a line in a rock, it takes a fair amount of work for it to wear away. The deeper the groove, the longer it takes to wear down.
The amount of time it takes to break habits, including undesirable eating habits, is proportionate to how long you’ve had the habit.
Here's an example. Let's say you have a supervisor at work who does things that frustrate you. An average of four times a day, the supervisor does something you find frustrating. You decide to reward yourself with food each time. That means that you reward your frustration with food around 1,460 times each year. If you’ve been doing it for seven years, you’ve repeated your habit over 10,000 times! That’s a lot of reinforcement!
So what does all this line in rock stuff have to do with anything? It is analogous to how our brains work.
When you break an eating habit, or any habit, you’re actually erasing circuitry in your brain and establishing new circuitry.
I’ve written previously about how our brains like to be efficient to use less of our energy. Habits are a way our brains can be more efficient. Think about how automatic driving a car is for you now compared to when you were first learning to drive. You’ve developed habits around driving which have made it a lot easier. The same is true for habits like mindless eating.
In my experience, the number of repetitions of a new habit is more important than the number of weeks or months. Let’s take the example of the person who eats because of frustration at work. Every time she gets frustrated, she will have a thought to eat something so she doesn’t have to feel her emotions or to reward herself for having to deal with this supervisor. Because she’s had this thought so many times, she may not even notice it! To change the habit, she’ll have to make a point of noticing the thought before she eats, then using the more developed part of her brain to choose NOT do it. She can mindfully replace the thought to eat something with a better thought like, “Eating when I’m not hungry does nothing to change my supervisor's behavior.” That opens the door to looking at what is really causing the frustration, and addressing it with a real solution.
The good news is that you CAN break these habits and establish new ones. You can do this by noticing your unproductive thought and replacing it with a better thought, over and over.
Once you’ve repeated the new habit enough times, you won’t even think about the old one. The new one will become automatic.
If you started eating to avoid your emotions a year ago when your mother died, it may be easier to rewire that circuitry than if you started doing it in adolescence and are now 45.
The sooner you start, the sooner you’ll break those eating habits that are keeping you from losing weight and realizing your dreams!
A year from now, you'll be glad you started today!

domain: psychology


Emerging phonk producers Killbird and GADOR are set to make waves in the electronic music scene with their highly anticipated collaborative track, “Wait For Me Again.” This synth-heavy banger showcases their exceptional production quality and unique approach to the genre. With its catchy hooks and standout vocals, this track is sure to captivate fans of electronic music. Scheduled for release on May 26th through the renowned NOKTURNE imprint by Arise Music Group, “Wait For Me Again” is a must-listen for any music enthusiast seeking fresh and innovative sounds.
An Overview of Phonk
Phonk, a subgenre of electronic music, has been gaining momentum in recent years. Combining elements of trap, hip-hop, and lo-fi aesthetics, phonk has carved its niche in the music industry. Characterized by its eerie, nostalgic samples and heavy use of bass, this genre offers a unique listening experience that appeals to a diverse audience. The emergence of phonk has brought forth talented producers who continue to push the boundaries of the genre, including Killbird and GADOR.
The Rise of Killbird and GADOR
Killbird and GADOR are two emerging talents within the phonk scene who have garnered attention for their exceptional production skills and distinct musical styles. Both artists have individually made significant strides in their careers, releasing a string of successful singles that have captivated listeners. The collaboration between these two promising producers has generated considerable anticipation among fans and industry insiders alike.
“Wait For Me Again” – A Synth-Heavy Banger
“Wait For Me Again” serves as the perfect introduction to the musical prowess of Killbird and GADOR. The track begins with a captivating bassline that immediately draws the listener in. As the beat intensifies, the song comes alive with a flurry of intricate synth melodies that intertwine seamlessly. This carefully crafted sonic landscape showcases the duo’s ability to create captivating and immersive musical experiences.
Production Quality and Vocals that Set “Wait For Me Again” Apart
What truly sets “Wait For Me Again” apart from other phonk tracks is the exceptional production quality and the use of catchy vocals. While many phonk songs rely heavily on samples and instrumental elements, Killbird and GADOR demonstrate their ability to blend these traditional phonk elements with innovative production techniques. The result is a track that stands out in terms of its sonic richness and attention to detail.
In addition to the impressive production quality, the vocals featured in “Wait For Me Again” add an extra layer of depth and appeal. Unlike many other phonk tracks, which often focus on instrumentals and samples, Killbird and GADOR’s collaboration incorporates memorable vocal lines. This inclusion provides a refreshing twist to the genre, further distinguishing their work from the rest of the phonk landscape.
Release Details and Future Expectations
Scheduled for release on May 26th via the prestigious NOKTURNE imprint by Arise Music Group, “Wait For Me Again” is poised to make a significant impact on the electronic music scene. The support of a well-established label and the impressive track record of Killbird and GADOR heighten expectations for this release. With their innovative sound and meticulous attention to detail, the duo is poised for success in the industry.
As “Wait For Me Again” gains traction, it is likely to attract a growing fan base and pique the interest of music enthusiasts seeking fresh and distinctive electronic sounds. Killbird and GADOR’s collaborative effort demonstrates their ability to push boundaries and redefine the phonk genre. Their commitment to creativity and excellence sets the stage for continued growth and success in their respective careers.
Killbird and GADOR’s collaborative track “Wait For Me Again” is a testament to their exceptional talent as emerging phonk producers. With its infectious bassline,


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Everything you need to know about Meringue is here! Meringue is mostly known in French, Italian and Swiss cuisines and are made by whisking egg whites with sugar. The mixture can be baked for several hours so that it is gently baked and holds its shape. Home made meringues are crisp on the outside with a soft center, whilst commercially made meringues are crispy throughout. Many people shy away from making their own meringues but like so many other culinary challenges, there is a knack to learn and once you have mastered it, the result is truly delicious! Everything you need to know about meringue is included in this article!
What is the history of Meringue?
There are various stories about the origins of meringue, but the most popular, tells of a Swiss pastry chef called Gasparini who in 1720 discovered how to make meringues. He used numerous small meringues – that he formed using two small spoons – to decorate an array of desserts including ice creams, mousse and fruit.
Today there are three main different types of meringues. They are all made using egg whites and sugar – with a few differences in technique.
Types of Meringue
This meringue is the most usual type of meringue and is made by whisking egg whites until the mixture stands in stiff peaks. Sugar is then slowly whisked in. Once all the sugar has been added, the meringue is whisked for a few more moments until it is silky and glossy to look at.
Italian meringue is the most complex meringue to make as it involves a little sugar cookery, but, having said that, it is well worth the effort as it is a lovely stable meringue to work with. Italian meringue is made by whisking the egg whites until they form soft peaks and then whisking in a hot sugar syrup (121º C/ 250ºF). Lemon juice or cream of tartar is often added as this will make the mixture very stable.
Swiss meringue is made in the same way as French meringue, but once the sugar has been whisked in, the meringue mixture is then placed in a bain-marie (similar to a double boiler). The meringue is then heated to 75ºC (170ºF) and tested with a sugar thermometer before it is removed from the heat.
The meringue is then whisked again to form soft peaks and vanilla essence or vanilla paste is sometimes added. Whisking continues until the meringue is glossy and forming soft, medium or stiff peaks -whichever is desired. It is important to remember that because it is made in a different way, Swiss meringue is not as light and voluminous as French meringue and tastes like the softest marshmallow.
Popular Desserts with Meringue
Meringue can be used to create some stunning looking puddings and cakes that taste every bit as good as they look. A number of the most popular puddings have interesting histories too.
The Lemon Meringue Pie for example, was created in the early 19th century in America’s first cookery school, whilst Baked Alaska was created by the chef at Antoine’s in New Orleans to mark the acquisition of Alaska by the United States from Russia on 10 March 1867. Eton Mess is a tasty combination of meringues, strawberries and cream, that was first served in 1893 to spectators at the cricket match between Eton College and Harrow School.
In 1926 The first meringue-based Pavlova was served in the Wellington Hotel in New Zealand. It was made to celebrate the tour to Australia and New Zealand by the Russian ballerina, Anna Pavlova.
In France, without a doubt, the most popular meringues are the small multi-colored macarons which are a national favorite Macarons were first made by the Italian chef working for Catherine de Medici who was Queen in France from 1547 to 1559. The macarons are made from egg white and sugar, with the addition of ground almonds and food coloring.
FAQs: Everything you need to know about meringue
How can you use Meringue in baking?
Once you have mastered making meringue you will find it really versatile as it can be used for the topping for pies and tarts. The key to success is that the more sugar used in the recipe, the crisper the meringue, and less sugar produces a softer meringue. Meringue can also be successfully used as a topping for a cake rather than icing or buttercream. If you are making a cake for a special occasion, the traditional icing to use is Royal Icing and this is made using a soft meringue mixture in the early stages.
There are so many lovely recipes to try including floating islands which are spoonfuls of fluffy meringue in a pool of creamy custard sauce and meringue nests that can be filled with whipped cream and soft fruit. The usual accompaniment to crisp meringues is whipped cream, although you can make a flavored buttercream to sandwich small meringues together instead.
Can meringue cookies be gluten free, sugar free and vegan?
Traditionally made meringues with egg white and sugar are gluten free. Even if you are making an Italian-style meringue that needs cream of tartar, the dish can still be enjoyed by those on a gluten free diet.
Making meringues without sugar sounds quite a challenge as sugar is one of the main ingredients, but it can be successfully done – which is great news for those on the Keto, paleo or low sugar diets. The secret is to use inulin (made from chicory root) as the sweetener and powdered erythritol. For every two egg whites you will need 40g inulin and 30g powdered erythritol. The result is great – tasty, crispy low-carb meringues or the perfect Eton Mess!
If you want to enjoy meringues but are vegan, the good news is that meringues can be made using the water strained from a can of chickpeas (aquafaba) that is then whisked with sugar. The process is easy but it does take about ten minutes to whisk the meringue mixture enough to hold its shape. The effort is well worth it and the meringues can be enjoyed with fruit and soy cream.
Many home cooks keep a tub of meringue powder in the pantry as this can be used at short notice. If you are planning to serve it to people with dietary needs, it is best to check the ingredients panel as it can contain corn starch.
Can your freeze meringue?
If you have any spare meringues or a cake with a meringue topping, both can be successfully frozen for up to one month in the freezer. This is best done using a rigid airtight freezer container and layering the meringues between sheets of parchment paper or wrapping the cake so that it is airtight.
The key to success is to defrost the meringues very carefully, ensuring that there is no chance for them to absorb any moisture as this will soften them.
Egg whites can be very successfully frozen – so this is the perfect way to store any spare egg whites. The egg whites can be successfully frozen individually in an ice cube tray.
Final tips about meringue
Meringues can be easily bought in many cake shops, patisseries and supermarkets. Store meringues definitely taste good until you have tasted home made meringues! If you have never made meringues, why not try making some classic French meringues to begin with? The best tips of all are to use parchment paper to ensure the meringues do not stick and not to open the oven door until the meringues have cooled completely or else they will crack. In both cases, it is only the look of the meringues that is impacted – they still taste really good!
Check out our recipe: How to make Italian Meringue – We Desserts
Check out our recipe: How to make French Meringue Cookies – We Desserts

domain: food


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1997 Volkswagen Golf CL 2.0L For Sale
Good body, great engine, new axle rod, new power steering, brake rotors, radiator, gaskets, bulb holders, steering boot, $1500 on the transmission and clutch, new mufflers (last year). 103,000KM. Great for VW aficionados. Just put $2508 in repairs into it ... runs great now!!
$4000 CDN obo.


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Award-winning author of adult and kids’ books Phil Burrows explores the many issues facing kids and reading in the modern world.
Brad Nagle offers an unfiltered view into the rollercoaster ride that is parenthood.
The NSW Government in Australia has acknowledged the growing demand for creative skills in the digital world, with a cash bonus to encourage children into coding.
The Dad Website’s health and fitness guru and Ultimate Dad Transformation blogger Stefano Chiriaco reveals three secrets to transforming your body and mind in 2018.
Splitting with the mother of your children brings a whole new dynamic to dealing with the in-laws, writes this British dad-blogger.
Father-and-son distance running duo Dick and Rick Hoyt’s story is nothing short of remarkable – and captures the very essence of fatherly love.
Healing Sounds founder and dad Charles Carpenter advocates the power of music to improve children’s literacy skills.


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The Chapel In Southern California That’s Located In The Most Unforgettable Setting
Perhaps you’ve passed by this chapel many times, but have you ever had an opportunity to take a closer look at the stunning grounds of this historic landmark in Southern California? Located in Santa Barbara, you’ll want to take some time to explore the beauty of the architecture and the landscape that surrounds this piece of history.
Old Mission Santa Barbara is located at 2201 Laguna Street in Santa Barbara. Tours of the chapel, surrounding grounds, and other mission buildings are offered daily.
Want to see a few more beautiful churches in Southern California? You can take a look at some more architectural beauties by heading over here.
Southern California In Your Inbox
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domain: geography


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New Delhi ,
The Kentucky Derby is the most popular horse racing event in the United States. You could ask nearly anyone about horse racing and this race comes up by name.
Kentucky Derby odds vary each year depending on the horses that are competing. Below you can see just how to bet on the Kentucky Derby.
Where to Begin
Depending on where you live, you need to make sure you have access to a reputable sportsbook to take wagers. Whether this is in person or online, finding a legal sportsbook is going to be your first step.
If you have some sportsbooks in mind, check to make sure they are legal and showcase this information freely. Upon signing up, you should look for various payment methods and ease of navigating the website.
Once you feel comfortable with the sportsbook of choice, check to see if there are any welcome bonuses or deposit bonuses. These will give a boost to your betting experience and allow you a little extra cash for your bets. Just check the fine print before you agree, as some of these might require you to do extra.
If you are new to Kentucky Derby betting, the best option would be to pick an outright winner. There are other betting options that you can consider later on, but only if you are ready for the challenge.
Types of Bets to Place
Picking an outright winner is the most straightforward bet to make. This typically pays out well, especially if the horse you chose was considered an underdog.
Below are the betting options you could see:
Place: This bet pays out if your choice finishes first or second.
Show: This bet is the correct pick for your horse to finish first, second, or third.
Exacta: Correctly pick the first two horses in order.
Trifecta: Correctly pick the first three horses in order.
Superfecta: Correctly pick the first four horses in order.
Super High Five: Correctly pick the first five horses in order.
Other special bets include a double pick on the Kentucky Oaks (Friday race) and the Kentucky Derby (Saturday race), where you have to try to correctly pick the winner of both races.
Finding the Right Choice
Picking the correct horse to win is quite difficult. However, it can be done with some proper research and luck.
Data is going to be your best friend when it comes to looking at horses that could win. This could mean looking at speed numbers, previous performances, ratings on horses, and even how well the jockeys have performed.
Looking at every horse and jockey combination to find a winner is crucial to succeeding at Kentucky Derby betting. In addition, you could also watch footage of horses you have picked out and how well they have raced.
Which Horse is Best?
Out of the 20 or so horses that you have to do research on, it would be best if you stick within the top 10. This does not mean that the top 10 with the best odds are going to win, it just means that this is a good place to do your research.
The favorite to win does not always win, but in horse racing, it is a pretty good measurement of who will succeed. Doing your own research is the best way to find value and to find the horse that is going to help you out.
Even if you do not go for the exact winner, you could look to engage in other bets like the place or show bets. Doing research on the top 10 allows you to get a good read on the competition and the information needed to do those specific bets.
How Much Should You Bet?
Not everyone has money to blow on this event, but that does not mean you cannot throw some smaller amount on a horse to win. The first step would be figuring out your finances and going from there.
Betting as little as $50 or $10, whatever your budget can hold, can still make a difference if you do win. You always want to make sure this money is something that you can afford to lose.


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I Hate Fairyland, Volume 6: Last Gert Standing (I Hate Fairyland #6) – by Skottie Young, and Brett Bean
Paperback – Image – January 2024 – 128 pages
Death by a thousand Gerts! King Cloudeus is determined to finish what his sister Queen Cloudia never could: kick Gert out of Fairyland FOR GOOD! And the only way to do that is have every Gert who ever lived battle each other to the death. Who said there’s only so many Gerts to go around?! They clearly haven’t read this comic. OG Gert returns to find the last key to escape, but is it too late, and will she become a Lifetime Citizen of Fairyland?
Collects I HATE FAIRYLAND #6-10

domain: artistic


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Bandai Spirits Ichibansho is proud to announce their newest release from Dragon Ball Z: Broly - The Legendary Super Saiyan: Legendary Super Saiyan Broly (Vs Omnibus Z)! This figure is expertly crafted and meticulously sculpted to look like Super Saiyan Broly from the anime. Standing at approximately 12 inches tall, Legendary Super Saiyan Broly(Vs Omnibus Z) is seen in his popular pose.
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Food & Drink
Historic Recipe File
For over 20 years, from the 1960s until the 1980s, Milwaukee Public Library librarians clipped hundreds of recipes from the Milwaukee Journal and Milwaukee Sentinel. They were used at Ready Reference to answer telephone questions before recipes were available online.
The Historic Recipe File digital collection is comprised of the clipped recipes. Many favorite foods appear in this collection providing a fascinating glimpse into the local and ethnic foods that were popular in Milwaukee's past.
This digital collection is a work in progress and recipes appear as they are converted into digital files. If you have questions about this collection, please contact MPL’s Business & Technology Department at (414) 286-3051.
Explore Our Suggestions:
- Sweets & Desserts
- Cooking - General
- Vegetarian & Vegan
- Beer, Wine & Spirits
- Slow Cooking & Meal Prep
- Regional Cooking
by Bill Leung, Judy, Leung, Kaitlin Leung, and Sarah Leung
The Leung Family share generations of family recipes, and their fascinating family history.View on CountyCat
by Anita Jaisinghani
Go inside the mind of a chef to learn the fundamentals of Indian cuisine and decode the secrets to cooking with spices in this beautiful collection of over 100 timeless recipes.View on CountyCat
by Jorge Gaviria
by Jacques Pepin
From legendary chef Jacques Pepin, a book celebrating his lifelong love of chickens, featuring dozens of his celebrated paintings and more than 50 recipes, along with a treasure trove of poignant and often humorous stories.View on CountyCat
by Rachel Farnsworth
A beautiful hardcover cookbook containing all the family and fan favorites from the popular Stay-at-Home Chef websiteView on CountyCat
by Taste of Home
Savor all of your fall favorites with autumn's best baked goods in this collection of more than 275+ mouthwatering recipes.View on CountyCat
by Taste of Home
Whether you live in or long for the country, you can now share your love of farmhouse foods with everyone on your invite list.View on CountyCat
by Esteban Castillo
In this companion cookbook to Chicano Eats, the blogger, and winner of the Saveur Best New Voice People’s Choice Award shows off the sweet and dreamy side of Chicano cuisine in 80 recipes for irresistible desserts, cakes, tamales, pan dulce and drinks.View on CountyCat
by America's Test Kitchen
Why eat out? Bring home the bistro and make your table the delicious place everyone wants to linger, with more than 150 classic and modern dishes to share.
by John Kanell
Decadent, delicious seasonal comfort foods and desserts you can make at home no matter what your cooking level from the beloved social media star @PreppyKitchen.View on CountyCat


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Selecting just one song as the top song of a year is never an easy task. Each artist is different, and many different artists have delivered quality songs worthy of being crowned as the song of the year here at Country Perspective. There were three songs that Josh and I ultimately had this narrowed down to for song of the year. Sturgill Simpson’s “Turtles All The Way Down” defined the best country album of the year with its use of classic country sounds with some modern electronic effects to create a truly unique, and equally great, country song. Karen Jonas’ “Oklahoma Lottery” stood out with her haunting delivery of a family stricken by the hardships of a drought. A topic that’s hardly brushed upon in country music, Karen sells the story and captures the appropriate mood with an incredible blues influenced country production. However, those two songs didn’t quite measure up to the third option. Josh and I both agreed that Country Perspective’s 2014 Song of the Year winner is Tami Neilson’s “Cry Over You.”
Tami Neilson has been compared to Patsy Cline, and rightfully so. She has a strong, captivating voice that grabs your attention from the first note. Her new album, Dynamite!, was another favorite album this year, and this song is the standout of that album. On “Cry Over You,” Neilson covers a great area of vocal notes: dropping to the lower spectrum during the verses and soaring to the higher end on the chorus. More importantly, she comfortably and impressively hits every note she touches. Tami doesn’t stretch herself in an attempt to add extra, unnecessary emphasis. From the first listen, I was sold on this vocal performance.
What makes “Cry Over You” stand out the most from its counterparts is the timeless musical production behind Tami. There’s no attempt to modernize the sound here. “Cry Over You” is a simple, historical recreation of the sound that made country music great. The song could have been released 60 years ago and still not sound out of place. Patsy could have sang this song, so could Tammy Wynette, Kitty Wells, Loretta Lynn, the list goes on; simply put: “Cry Over You” is timeless, it’s universal, and it’s brilliant. Tami Neilson deserves every accolade she’s been awarded; she continues to release music at the best quality, and “Cry Over You” is the best example of top-notch quality music.
Congratulations to Tami Neilson for recording and releasing “Cry Over You”: Country Perspective’s 2014 Song of the Year!


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The first in a two-part series, this article examines the drivers for 10GbE deployment for high-performance cluster computing (HPCC) environments and related technology trends. Ten Gigabit-per-second Ethernet (10GbE) represents the next level of Ethernet network bandwidth, with networking vendors promoting it as the next great capability. But high-performance computing (HPC) infrastructure and operations professionals must strike a balance between constant operational improvement and sound financial decision-making. So far, 10GbE has been a high-end luxury for environments that want maximum performance regardless of cost, ...
CloudSlam'10 ™ – a virtual conference to promote collaborative analysis of recent trends and challenges in the world of Cloud Computing will begin on March 23. CloudSlam'10 ™ is organized by leading experts and authorities in the industry and sustained Cloud Computing the largest community in the world cloud. Key topics will include Cloud standards, security, transition Strategies, compliance and the impact of cloud computing on the world economy. Participants will hear the latest news, views and opinions that are exclusive to CloudSlam'10 ™. style = "color: # ... Read More
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The Ombudsman's final decision:
Summary: the Ombudsman considers there is no fault by the care provider in charging for a notice period after Mrs X left a care home. However, the provider miscalculated the refund by two days and it will refund this to Mrs X.
- The complainant whom I shall refer to as Mr X, complained on behalf of his aunt Mrs X, that a residential care home failed to fully refund overpaid fees. He says the home owes her over £4000.
The Ombudsman’s role and powers
- We investigate complaints about adult social care providers. If there has been fault, we consider whether it has caused an injustice and, if it has, we may suggest a remedy. (Local Government Act 1974, sections 34H(3) and (4), as amended)
- If we are satisfied with a care provider’s actions or proposed actions, we can complete our investigation and issue a decision statement. (Local Government Act 1974, section 30(1B) and 34H(i), as amended)
How I considered this complaint
- I have
- considered the complaint and the copy correspondence provided by the complainant;
- made enquiries of the care provider and considered its comments and documents;
- discussed the complaint with the complainant’s representative; and
- invited his comments on my draft decision.
What I found
- Mrs X was living in a care home and paid the fees directly herself. In 2017 her nephew, Mr X helped her move out because she was distressed by the actions of other residents. She did not give any notice. Mr X said staff at the home told when leaving that they should give 4 weeks’ notice.
- Mr X asked the care provider for a refund of the fees as Mrs X had overpaid. He said that it owed her £8100. He also said the home had given him conflicting information about how the charges were calculated.
- The care provider sent Mrs X a refund for £3405. It said that Mrs X was required to give 4 weeks’ notice when leaving the home. It had charged this in lieu of notice.
- Mr X complained to the care provider and said he calculated that it still owed Mrs X at least £4695. He asked for a proper breakdown of the calculation because it had given conflicting information. He said Mrs X had not received a contract.
- In response to the Ombudsman’s enquiries the care provider said it had given Mr X the contract for Mrs X to sign before she moved in. However, it said he had not returned it despite the care manager calling to remind him. Mr X says he did not receive the contract and if he had he would have ensured it was signed and returned.
- The care provider does not have a record of the calls it says it made to chase up the return of the contract. It says it has revised its procedures to ensure that the contract is signed before the resident moves in or on the day they move in.
- I have considered whether there was fault by the care provider and whether it caused Mrs X injustice. There was no signed contract, and the provider should have insisted it was signed. This could be considered fault. However, the provider’s terms and conditions state that after an initial 4 week period as a resident, the resident must give 4 weeks notice if they intend to vacate. Notice periods are standard conditions in care home contracts. I consider that after the 4 week initial period Mrs X had accepted the terms and conditions as the home was providing and she was paying for the services even though she had not signed the contract. It could be said there was an implied contract on that basis and that Mrs X was liable to pay the notice period. I do not see that even if I found there was fault by the provider that this caused injustice to Mrs X.
- In its response to the Ombudsman’s enquiries the care provider set out the details of the refund it had given Mrs X. This included the charge in lieu of the 4 week notice period as detailed above. However, I considered calculation was not correct because the provider charged for 30 days after Mrs X left instead of the 28 day notice period. The care provider has apologised and agreed to refund the charge for two days as soon as possible.
- I have completed my investigation and closed the complaint because I find there is no fault by the care provider regarding the notice period charge.
Investigator's decision on behalf of the Ombudsman


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A. J. Casas-Reyes, F. Cerda-Ramirez, Y. Garza-Garcia, N. Balagurusamy, A. D. Ilyina
Application of bioluminescence
method for quality control of culture media and bacteria applied to standard
The aim of the study was to
develop a bioluminescence assay for the rapid monitoring of the quality of the
bacterial culture medium and quality of standard bacterial strain by way of ATP
detection, as well as to define the relationship between ATP and the bacterial
population estimated by MPN and CFU methods. The growth kinetics of E. coli in the Brilliant green bile
and Lactose broth, suggested by the NOM (Mexican Official Norms) were studied.
The influence of pH, ionic force, and temperature was also evaluated for E.
coli and E. coli co-inoculated with Pseudomonas spp. ATP was
detected by the bioluminescent method after dimethyl sulfoxide treatment and
simultaneously the bacteria present in the samples were enumerated by plating
and MPN techniques. All the parameters tested to compare the growth of bacteria
in brilliant green bile and lactose broth, were statistically significant. A
strong inhibition of growth was observed in both media containing 5% NaCl. An increase in specific growth constant of E.
coli was noted in presence of Pseudomonas spp. The relationship
between ATP, CFU and MPN of the cultures was established and it was observed
that the ATP assay has good correlation with CFU and MPN techniques.
Copyright (C) Chemistry Dept., Moscow State University, 2002


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We collect around 350 tons of wool annually, from 25 locations across Switzerland. The virgin wool is sorted by quality and regionally processed into products. Swisswool guarantees a short, traceable route from sheep to the shop. At the collection points, Swisswool collects all the wool produced during shearing. Completely without waste.
Learn more at: www.swisswool.ch

domain: agronomy


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BAg-1 is a brazing filler metal that is free-flowing with higher fluidity. This alloy can be used on most iron, copper and nickel-based alloys. Due to its narrow melting range this filler metal is less sensitive to the heating rate and therefore should not separate into low/high melting constituents. With this metal, in some instances special fluxes may be needed for optimum bonding and wetting.
Custom wire sizes and reels available. Also available in powder and paste form.

domain: chemistry


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When the jar is accelerated forward, the cork's inertia will ten to keep it at rest, thus it shift to the back of the jar. If the jar is accelerated to a slower speed, the cork's inertia will tend to keep moving, thus it will shift to the front of the jar.
When moving the jar in a circle, the cork's inertia will tend to keep the cork moving in a straight line, thus it shifts to the outside of the jar (directly away from the center).
When there is water in the jar the cork floats. All the the previous obervations will be opposite. The reason is that the water has more inertia then the cork and its inertial will result in the cork being displaced by the water. Thus, for example, as the jar is accelerated forward, the water tends to shift to the back of the jar, leaving the cork in the front of the jar.


Former Zenit FC player Kazachenok dies at 64Sport March 27, 1:37
Russian senior MP calls on EU politicians not to hide heads in sand in Syrian settlementRussian Politics & Diplomacy March 26, 18:09
Three Russian fans stabbed after football match in BelgradeSport March 26, 3:28
Russia ready to take part in restoring oil production in Syria - energy ministerBusiness & Economy March 26, 3:27
Moscow disappointed over new US sanctions against Russian companies - Foreign MinistryRussian Politics & Diplomacy March 26, 1:28
US sanctions 8 Russian companies over non-proliferation lawWorld March 25, 21:53
Russia's Defense Ministry says US-led coalition unlikely to launch battle for Raqqa soonRussian Politics & Diplomacy March 25, 19:06
Russia cuts oil production by 185,000 barrels per day as of today — energy ministerBusiness & Economy March 25, 18:30
OPEC has no objections to speed of Russia's oil production cutsBusiness & Economy March 25, 12:38
MOSCOW, May 6. /TASS/. A total of 27 foreign heads of state and government will come to Moscow to attend Victory Day celebrations, Russian presidential aide Yury Ushakov told reporters on Wednesday.
"In all, 27 heads of state and government," he said, referring to high-ranking foreign guests of the festive celebrations in the Russian capital.
According to Ushakov, the Victory Day celebrations in Moscow that will take place between May 8 and May 10 will be attended by the leaders of Azerbaijan, Armenia, Belarus, Kazakhstan, Kyrgyzstan, Tajikistan, Turkmenistan, Abkhazia, South Ossetia, China, South Africa, India, Bosnia and Herzegovina, Venezuela, Vietnam, Germany, Egypt, Cyprus, North Korea, FYR Macedonia, Mongolia, Palestine, Serbia, the Czech Republic and Zimbabwe. UN Secretary-General Ban Ki-moon and UNESCO Director-General Irina Bokova will also be taking part in the celebrations.


George Clooney and Elisabetta Canalis were one of the hottest celebrity couples for quite some time in Hollywood, but since their breakup the star celebs appear to have moved on to other romantic partners. Clooney and Canalis are both very much involved involved with other people. He is dating a female professional wrestler named Stacy Keibler and she is dating a Jackass now — literally. She’s been romantically linked to Steve-O.
When Elisabetta Canalis told the media she expected to get married and have children someday, she found herself out on the street fairly quickly last year. At that point, Clooney and Canalis hit a brick wall in their relationship and with a few short weeks she was out of his life (presumably once and for all) thought most entertainment news magazines, but now not everyone is so sure. New rumors are surfacing in Italian tabloids that claim things might not be so perfect now in either star celebrities’ world.
After the breakup with George Clooney, she hooked up with Mehcad Brooks (the HBO series actor from True Blood that played “Eggs”) and Steve-O from the television and movie series Jackass (who she was spotted in Europe on vacation with on March 30th, 2012). She and the reality television star are both vegetarians into animal rights.
But rumors are starting to surface that humanitarian Clooney and Canalis are both having relationship troubles with their respective partners. He has been accused of faking his relationship with Keibler (who is allegedly an old family friend who merely agrees to make public appearances with him but spends virtually no time alone with him at all) and she’s been spotted making that same mean break up face she used to make during her last months with actor George Clooney.
For more information about Elisabetta Canalis, George Clooney’s most famous ex check out these celebrity gossip and entertainment news trivia articles:
- George Clooney ex girlfriend Elisabetta Canalis dating a Jackass?
- Dancing With The Stars 2011: Why was PETA model Elisabetta Canalis kicked off so early?
- Celebrity Couples: George Clooney and Elisabetta Canalis confirm split?
What do YOU think? Will George Clooney and Elisabetta Canalis ever get back together?
Love reading celebrity news and trivia about the Hottest celebrity couples in Hollywood? Follow @celebritycouple on Twitter.


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An Improved PIII/PV?O-Catalyzed Reductive C-N Coupling of Nitroaromatics and Boronic Acids by Mechanistic Differentiation of Rate- and Product-Determining Steps.
ABSTRACT: Experimental, spectroscopic, and computational studies are reported that provide an evidence-based mechanistic description of an intermolecular reductive C-N coupling of nitroarenes and arylboronic acids catalyzed by a redox-active main-group catalyst (1,2,2,3,4,4-hexamethylphosphetane P-oxide, i.e., 1·[O]). The central observations include the following: (1) catalytic reduction of 1·[O] to PIII phosphetane 1 is kinetically fast under conditions of catalysis; (2) phosphetane 1 represents the catalytic resting state as observed by 31P NMR spectroscopy; (3) there are no long-lived nitroarene partial-reduction intermediates observable by 15N NMR spectroscopy; (4) the reaction is sensitive to solvent dielectric, performing best in moderately polar solvents (viz. cyclopentylmethyl ether); and (5) the reaction is largely insensitive with respect to common hydrosilane reductants. On the basis of the foregoing studies, new modified catalytic conditions are described that expand the reaction scope and provide for mild temperatures (T ? 60 °C), low catalyst loadings (?2 mol%), and innocuous terminal reductants (polymethylhydrosiloxane). DFT calculations define a two-stage deoxygenation sequence for the reductive C-N coupling. The initial deoxygenation involves a rate-determining step that consists of a (3+1) cheletropic addition between the nitroarene substrate and phosphetane 1; energy decomposition techniques highlight the biphilic character of the phosphetane in this step. Although kinetically invisible, the second deoxygenation stage is implicated as the critical C-N product-forming event, in which a postulated oxazaphosphirane intermediate is diverted from arylnitrene dissociation toward heterolytic ring opening with the arylboronic acid; the resulting dipolar intermediate evolves by antiperiplanar 1,2-migration of the organoboron residue to nitrogen, resulting in displacement of 1·[O] and formation of the target C-N coupling product upon in situ hydrolysis. The method thus described constitutes a mechanistically well-defined and operationally robust main-group complement to the current workhorse transition-metal-based methods for catalytic intermolecular C-N coupling.
Project description:A main group-catalyzed method for the synthesis of aryl- and heteroarylamines by intermolecular C-N coupling is reported. The method employs a small-ring organophosphorus-based catalyst (1,2,2,3,4,4-hexamethylphosphetane) and a terminal hydrosilane reductant (phenylsilane) to drive reductive intermolecular coupling of nitro(hetero)arenes with boronic acids. Applications to the construction of both Csp2-N (from arylboronic acids) and Csp3-N bonds (from alkylboronic acids) are demonstrated; the reaction is stereospecific with respect to Csp3-N bond formation. The method constitutes a new route from readily available building blocks to valuable nitrogen-containing products with complementarity in both scope and chemoselectivity to existing catalytic C-N coupling methods.
Project description:The first intermolecular carbonyl arylations via transfer hydrogenative reductive coupling are described. Using rhodium catalysts modified by tBu2PMe, sodium formate-mediated reductive coupling of aryl iodides with aldehydes occurs in a chemoselective fashion in the presence of protic functional groups and lower halides. This work expands the emerging paradigm of transfer hydrogenative coupling as an alternative to pre-formed carbanions or metallic reductants in C?X addition.
Project description:A small-ring phosphacycloalkane (1,2,2,3,4,4-hexamethylphosphetane, 3) catalyzes intramolecular C-N bond forming heterocyclization of o-nitrobiaryl and -styrenyl derivatives in the presence of a hydrosilane terminal reductant. The method provides scalable access to diverse carbazole and indole compounds under operationally trivial homogeneous organocatalytic conditions, as demonstrated by 17 examples conducted on 1 g scale. In situ NMR reaction monitoring studies support a mechanism involving catalytic PIII/PV?O cycling, where tricoordinate phosphorus compound 3 represents the catalytic resting state. For the catalytic conversion of o-nitrobiphenyl to carbazole, the kinetic reaction order was determined for phosphetane catalyst 3 (first order), substrate (first order), and phenylsilane (zeroth order). For differentially 5-substituted 2-nitrobiphenyls, the transformation is accelerated by electron-withdrawing substituents (Hammett factor ? = +1.5), consistent with the accrual of negative charge on the nitro substrate in the rate-determining step. DFT modeling of the turnover-limiting deoxygenation event implicates a rate-determining (3 + 1) cheletropic addition between the phosphetane catalyst 3 and 2-nitrobiphenyl substrate to form an unobserved pentacoordinate spiro-bicyclic dioxazaphosphetane, which decomposes via (2 + 2) cycloreversion giving 1 equiv of phosphetane P-oxide 3·[O] and 2-nitrosobiphenyl. Experimental and computational investigations into the C-N bond forming event suggest the involvement of an oxazaphosphirane (2 + 1) adduct between 3 and 2-nitrosobiphenyl, which evolves through loss of phosphetane P-oxide 3·[O] to give the observed carbazole product via C-H insertion in a nitrene-like fashion.
Project description:A method for electrophilic sulfenylation by organophosphorus-catalyzed deoxygenative O-atom transfer from sulfonyl chlorides is reported. This C-S bond-forming reaction is catalyzed by a readily available small-ring phosphine (phosphetane) in conjunction with a hydrosilane terminal reductant to afford a general entry to sulfenyl electrophiles, including valuable trifluoromethyl, perfluoroalkyl, and heteroaryl derivatives that are otherwise difficult to access. Mechanistic investigations indicate that the twofold deoxygenation of the sulfonyl substrate proceeds by the intervention of an off-cycle resting state thiophosphonium ion. The catalytic method represents an operationally simple protocol using a stable phosphine oxide as a precatalyst and exhibits broad functional-group tolerance.
Project description:A single ruthenium complex catalyzes two discrete transformations resulting in the net conversion of an acetylenic pyrrole and alcohols to products of carbonyl anti-(?-amino)allylation. An initial catalytic process enables isomerization of an alkyne to a kinetically more reactive allene. A second catalytic process promotes alcohol-to-allene hydrogen transfer to form an aldehyde-allylruthenium pair that engages in regio- and diastereoselective carbonyl addition. A related reductive coupling of aldehydes mediated by 2-propanol also is described. The present catalytic processes represent rare examples of the use of alkynes as nucleophilic allylmetal precursors.
Project description:Herein, we disclose Ru(II)-catalyzed regioselective distal C(sp2)-H arylation of quinoline N-oxide with arylboronic acids to 8-arylquinolines. In the developed method, the Ru(II)-catalyst shows dual activity, that is, distal C-H activation of quinoline N-oxides followed by in situ deoxygenation of arylated quinoline N-oxide in the same pot. The current catalytic method features use of Ru metal as the catalyst and arylboronic acids as the arylating source under mild reaction conditions. Use of the Rh(III)-catalyst in place of Ru(II) under the same conditions afforded 8-arylquinoline N-oxides with excellent regioselectivity. Furthermore, the developed Ru(II) catalytic system is also extended for the C(sp2)-H arylation of indolines, N-tert-butylbenzamide, and 6-(5H)-phenanthridinone. Formation of the quinoline N-oxide coordinated ruthenium adduct is found to be the key reaction intermediate, which has been characterized by single crystal X-ray diffraction and NMR spectroscopy.
Project description:A method for the annulation of amines and carboxylic acids to form pharmaceutically relevant azaheterocycles via organophosphorus PIII/PV redox catalysis is reported. The method employs a phosphetane catalyst together with a mild bromenium oxidant and terminal hydrosilane reductant to drive successive C-N and C-C bond-forming dehydration events via the serial action of a catalytic bromophosphonium intermediate. These results demonstrate the capacity of PIII/PV redox catalysis to enable iterative redox-neutral transformations in complement to the common reductive driving force of the PIII/PV couple.
Project description:We report that a regioselective reductive transposition of primary allylic bromides is catalyzed by a biphilic organophosphorus (phosphetane) catalyst. Spectroscopic evidence supports the formation of a pentacoordinate (?(5)-P) hydridophosphorane as a key reactive intermediate. Kinetics experiments and computational modeling are consistent with a unimolecular decomposition of the ?(5)-P hydridophosphorane via a concerted cyclic transition structure that delivers the observed allylic transposition and completes a novel P(III)/P(V) redox catalytic cycle. These results broaden the growing repertoire of reactions catalyzed within the P(III)/P(V) redox couple and suggest additional opportunities for organophosphorus catalysis in a biphilic mode.
Project description:Natural availability of carbonyl groups offers reductive carbonyl coupling tremendous synthetic potential for efficient olefin synthesis, yet the catalytic carbonyl cross-coupling remains largely elusive. We report herein such a reaction, mediated by hydrazine under ruthenium(ii) catalysis. This method enables facile and selective cross-couplings of two unsymmetrical carbonyl compounds in either an intermolecular or intramolecular fashion. Moreover, this chemistry accommodates a variety of substrates, proceeds under mild reaction conditions with good functional group tolerance, and generates stoichiometric benign byproducts. Importantly, the coexistence of KO t Bu and bidentate phosphine dmpe is vital to this transformation.
Project description:A new methodology to form C(sp3 )-C(sp2 ) bonds by visible-light-driven intermolecular reductive ene-yne coupling has been successfully developed. The process relies on the ability of the Hantzsch ester to contribute in both SET and HAT processes through a unified cobalt and iridium catalytic system. This procedure avoids the use of stoichiometric amounts of reducing metallic reagents, which is translated into high functional-group tolerance and atom economy.


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Over 50 per cent of teenagers in the UK are not getting enough sleep.
Research by Oxford University has discovered sleep deprivation is rife for youngsters in school, with a natural change in hormone levels and increased usage of electronic devices identified as the main reasons for this, BBC News reports.
Teenagers are thought to need around nine hours of sleep a night in order to function properly and this is particularly important for those sitting GCSE exams. However, the study highlights how many school children cannot perform to the best of their ability due to sleepiness and this is something teachers need to keep their eyes on.
Russell Foster, professor of circadian neuroscience at Oxford University, noted the need for sleep is largely ignored despite the fact it is "fundamentally important".
"Within the context of teenagers, here we have a classic example where sleep could enhance enormously the quality of life and, indeed, the educational performance of our young people.
"Yet they're given no instruction about the importance of sleep and sleep is a victim to the many other demands that are being made of them," he added.
The rise in online gaming and social media is thought to be partly responsible for the issue, as increasing numbers of youngsters are spending time on these sites before they go to bed, or even when they are already in bed.
Professor Foster added the data shows how late night electronics use can boost alertness, which in turn makes it harder for children to drift off and secure a suitable amount of sleep.
Psychologist Jane Ansell has been coordinating some small-scale studies in schools and she found 20 per cent of pupils have fallen asleep in class at least once in the past two weeks, while 52 per cent were sleep deprived.
Teachers have an important role to play when it comes to encouraging teenagers to sleep more, as they can raise awareness of the issue.
Posted by Tim Colman