January 29, 2010
MU sophomore guard Kim English shoots against the Kansas defense Monday.
MU wrestler Max Askren competes against Nebraska's Craig Brester on Jan. 28, 2007, at the Hearnes Center. The Tigers beat the Huskers 31-11.
January 28, 2010
Hickman senior guard Lyle Harris, right, guards Rock Bridge senior guard Ricky Kreklow in Thursday night's rivalry game at Hickman High School. The Bruins defeated the Kewpies 72-70.
Hickman wrestler Austin Webb fights off getting pinned by Mexico wrestler Lindell Taylor during the 160-pound bout.
Hickman wrestler Adam Fraizer shakes hands with Mexico wrestler Monterio Burton after the 145-pound bout. Fraizer was pinned by Burton in Hickman's 60-16 loss to Mexico.
Hickman's Josh Browne, right, wrestles Mexico's Nathan Angel on Thursday at Mexico High School in Mexico, Mo. Browne won the 130-pound bout with a 17-8 decision.
Sophia Creach, 3, dances with her classmates during the Creative Movement class for three and four year olds at Dancearts of Columbia on Thursday.
Parker Rainwater, 3, stands off to the side as his mother and instructor Hallie Rainwater instructs the rest of the class, who are all girls. Parker will play the role of Peter Pan, and the other students will play 'lost girls,' in their Creative Movement class' recital piece this May, which Rainwater began teaching Thursday morning.
Jessica Coner, 4, glances at the mirror while doing an arabesque with Barney the Bear, alongside her instructor Hallie Rainwater. Jessica, who has been dancing for a year, is a student in the Creative Movement class for three and four year olds at Dancearts of Columbia.
Circuit Judge Gene Hamilton swears in a witness during the trial in November 2009 at the Boone County Courthouse in Columbia. He was delayed his retirement until September.
Karl Skala, Third Ward councilman, has been named to a national leadership training council.
Steve Schmidt trains four days a week in a shed behind his home in Leslie, MO, but alternates the muscle groups as to not cause injury. Schmidt has never hurt his jaw or chipped a tooth while performing teeth lifting.
J.D. Salinger, author of "The Catcher in the Rye," "Nine Stories" and "Franny and Zooey," is shown in this 1951 file photo.
January 27, 2010
President Barack Obama talks with members of Congress on Capitol Hill in Washington after delivering his State of the Union address. House Majority Leader Steny Hoyer of Maryland is at left and House Majority Whip James Clyburn of South Carolina is second from left.
President Barack Obama is greeted in the House chambers as he prepares to delivers his State of the Union address.
President Barack Obama delivers his State of the Union address on Capitol Hill in Washington in front of both the House and Senate and other guests in the gallery.
President Barack Obama gestures as he delivers his State of the Union address on Capitol Hill in Washington.
President Barack Obama delivers his State of the Union address on Capitol Hill in Washington on Wednesday. Vice President Joe Biden is behind the president.
The Rock Bridge girls basketball team laces up in pink to support breast cancer awareness.


This Old Bear Just Experienced Snow For The First Time Ever
He was in a cage his whole life.
It was summer, earlier this year, when life totally changed for a senior bear named Napa.
The roughly 20-year-old bear had been living in a concrete enclosure at a zoo in Serbia ever since 2009, when the country banned the use of wild animals in circuses.
Even though Napa had only known a life of coercion — being forced to perform for audiences — and confinement, having lived in cages all his life, even after retiring from the circus — people at Four Paws International were determined to give the bear the natural kind of life he never got to know before.
It was a long journey: Rescuers from Four Paws arrived in Serbia and brought Napa 900 miles by car and by suspended cable car — like a ski lift — over a lush valley in Switzerland to Arosa Bärenland, a new sanctuary for bears like Napa in the Swiss Alps.
And for the bear who suddenly had so much lush space to roam, it probably seemed like nothing could make his new home any more beautiful and joyful than it already was.
But then it snowed.
Earlier this month, as the weather turned colder, the picturesque sanctuary was dusted with a few inches of snow. And Napa couldn't be happier about it.
As little flakes swirled around him, Napa was caught on camera playing happily with a big log and then trying to do a somersault in the snow, with the carefree attitude of a cub.
"Napa had a blast!" Four Paws wrote on Facebook about the rescued bear's day in the snow.
Bears who are kept in captivity can't hibernate the way bears do in the wild — and it may take Napa some time to get in sync with the rhythms of nature that wild bears know by heart.
"We are not so sure yet if Napa will be able to hibernate this winter or not, as it might take a year for him to get used to his new environment," Jeta Lepaja, spokesperson for Four Paws, told The Dodo. "But as in Arosa winter will be cold and snowy he might actually go through [the] process."
Given Napa's response to the first snow of the season, there's little doubt he'll love his first winter of freedom at his gorgeous sanctuary — even if he ends up sleeping through it.


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Slovenian Turistic Towns
Slovenian towns grow from stories of love which have in the course of hundreds or even thousands of years adapted to the lively rhythms of modern life. Come to Ljubljana, the European Green Capital of 2016! Have a cup of coffee in the city centre, which is closed to motorized traffic, visit the renovated National Gallery, and dance the day away at one of the many street festival.After you have chosen your favourite bridge across the Ljubljanica, you can set off towards the beautiful coastal town of Piran.Or are you more interested in castle stories? Then go and explore medieval Ptuj, Slovenia’s oldest town. Choose your favourite town and make the most colourful memories of this summer.
Piran – a medieval pearl with Venetian architecture
Piran is a seaside town which has nurtured its medieval charm of narrow streets filled with the laughter of local fishermen for centuries.From any part of the town visitors can enjoy spectacular views of fishing boats, a lovely open-air market selling local produce, and the buzzing promenade with its many cafés and restaurants.The town is also renowned for the artistic flair of its seafront galleries.
Škofja Loka is the best-preserved medieval town in Slovenia.Two rivers wind their way through this picturesque little town dominated by Loka Castle (Loški grad) towering above their confluence.The old town is at its liveliest and most picturesque during summer months.Then, Škofja Loka remembers the Middle Ages with its Loški Historial events, proudly presents the Pisana Loka Festival, and displays works of art at the local arts festival LUFt.
Walking through Slovenia’s oldest town is like walking through the past. History speaks from numerous historical monuments scattered across the town, its medieval core, the castle above Ptuj, and the wine cellars reminiscent of the ancient Roman god Bacchus. Medieval streets of Ptuj come alive during the traditional ‘kurentovanje’ carnival, Roman Games, International Arts Festival, and other exciting events.
Idrija lies in a valley where pre-Alpine hills meet the Karst. The oldest mining town in Slovenia, Idrija is listed as a UNESCO heritage site due to its rich mercury mine heritage. The town’s best known ethnological feature is the Idrija lace, which has placed the town among the most renowned European centres of this valued craft.
Content received from: LosViajeros, https://losviajeros.net

domain: travel


text:
- Family Business
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THU 28TH MAY 2020
Keeping family firms informed of the latest news and developments when it comes to regulation, from employment to taxation and more besides.
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Living Wage Implications For Smaller Family Firms
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In a family business how do you deal with someone wanting to cash in their shares and how do you value them? Read More
Employment Law Changes
Upcoming changes to employment law that impact your family business. Read More
CGT Implications For Part Time Second Home Occupancy
Second homes – the capital gains tax implications of being a part-time occupier? Norma Stewart explains the changes to the tax rules on the sale of second properties. Read More
Proposed Cuts In Red Tape To Help Family Firms?
New proposals from the Government to reduce the burden of Red Tape... Read More

domain: law


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Freelance reporter Adam Kurkjian’s story goes like this: The Patriots had a trade in place for Rob Gronkowski.
Per Kurkjian, the Patriots had offers from both San Francisco and the Titans, and Patriots coach Bill Belichick brought this update to team owner Robert Kraft for a closed doors meeting. It was apparently during that meeting that word got back to Patriots quarterback Tom Brady. Brady then intervened and threatened to retire if Belichick and the Patriots followed through on such a trade. That made Kraft, not wanting to lose Brady in addition to Gronkowski, ultimately nix the deal.
The report was refuted by most, including Patriots PR head Stacey James.
Kurkjian, who said that he developed his trustworthy sources during his time with the Boston Herald, meanwhile, stood by his reporting during a Monday appearance with 98.5 The Sports Hub’s Toucher and Rich.
But speaking on Tuesday, Kraft himself shot the report down as much as one could.
“I guess when your team is good people are looking for things,” Kraft, speaking with reporters at the Myra Kraft Community MVP event, began. “I’ll just tell you it’s a bunch of hogwash that I vetoed some trade.
“That was never in the works. It’s just completely made up.”
In a drama-filled offseason, Kraft also expressed his frustration with what he considers to be irresponsible reporting.
“I think we have to be careful in society today that people can’t just come out and say things like this bit about us trading Gronk to the 49ers or Tennessee,” Kraft added. “There’s no basis to it and it gets a life of its own. I just want to go on record at today’s event to make sure that you all understand that there’s no truth that. People shouldn’t be able to do that.”
Although he was not at the since-canceled OTAs this week, the Patriots and Gronkowski reportedly continue to work on a restructuring the tight end’s current contract, which comes with an $8 million base salary in 2018 and $9 million base in 2019.
The 29-year-old Gronkowski caught 69 passes in 15 games last season, totaling 1,084 yards with eight touchdowns.

domain: news


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West Hertfordshire Hospitals NHS
Sentinel node biopsy
A Patient’s Guide
Sentinel node biopsy is a technique to improve the accuracy of operations that
take a small number nodes from the armpit (axillary node sampling). Axillary
sampling is advised in breast cancer operations in order to determine whether
any disease has spread to these glands, which is the first place the disease will
move to. It is important to know this, as it will affect the selection of subsequent
Sentinel node biopsy is a less extensive operation than the older axillary
sampling technique. Furthermore, axillary sampling is a less extensive operation
than the alternative where all the glands are removed (axillary clearance).
The technique involves injecting dye into the breast and selecting only the glands
in the armpit that pick up the dye. These are the most likely glands to show
disease if it has started to spread, as the disease will take the same route as the
To improve the accuracy of the technique, two dyes are used. The first is an
injection of a harmless amount of radioisotope on the day before the operation.
This is done in the nuclear medicine department at Hemel Hempstead. A scan of
the breast area is taken at about three hours after the injection, but after this you
can go home and be admitted the following day for your operation.
The second dye is a blue dye that is injected into your breast whilst you are
having the operation.
The operation is usually done at the same time as removing the breast tumour
and involves an incision in the armpit and the location of the glands by tracing the
blue dye and by following the radioisotope using a probe. The number of nodes
taken will vary, but on average will number two or three (leaving approximately
thirty nodes in the armpit).
Advantages of sentinel node biopsy
Sentinel node biopsy improves the accuracy of the axillary node sampling
It minimises the complications associated with the alternative of a full axillary
clearance (where all of the glands are removed). These include altered sensation
in the armpit and upper inner arm, shoulder stiffness, swelling of the arm in about
10% of operations (this is called lymphoedema) and post-operative fluid
Disadvantages of sentinel node biopsy
There is a very low incidence of allergic reactions to the dyes.
The blue dye can stain the breast for several weeks. In the day or two after the
operation it can stain your urine blue.
The technique may not work in a few cases where the dye does not travel to the
glands (less than 5%). In this situation the four most prominent glands will be
selected. There is a low probability of missing disease in the armpit (less than
The radioisotope injection involves an extra trip to Hemel Hempstead or Watford
General Hospitals on the day before the operation.
If any of the glands show cancer then we would recommend a further operation
to remove the rest of the glands. The technique is therefore probably not a good
idea if your surgeon estimates a higher than average chance of the cancer
having spread to the nodes. It would also be inappropriate if you would not want
or are unfit for a second operation. In these cases a full axillary clearance would
ST, November 2006

domain: medical


I couldn't even start the second mitten until I found out if I could get more yarn, so on Wednesday morning I went to Michaels first thing, and they not only had the same yarn, they still had the same dye lot! Ahhhh! So I grabbed it and went to Borders and spent the morning casting on and knitting the cuff. It is coming along nicely. The first few rounds of rib knitting in the round is tricky, but I got it all worked out eventually. And I found that the best way to join the two ends into the round is to slip one stitch from left to right and then slip one stitch over that from right to left so it's tightly connected.
On Thursday I gave my presentation to the Korean Medical Alumni Association, and it went off fine. About a dozen people in the audience, and the speech seemed well-received. And the handed me a check for $300 at the end for my trouble!
I worked on the mitten some more in the afternoon, and then had to go work in the testing office in the evening. But I have the thumb hole in place and am making pretty good progress. I will work on this all day today and should have it done today or tomorrow. Such fun! Oh except for sore fingers! Mittens are knit very tightly, using smaller than usual needles with worsted weight yarn, so there's a lot of pushing and pulling. I put my leather quilting thimble on my left forefinger, and that helps a lot. One poke with a bamboo needle doesn't hurt, but 1000 or maybe 10,000--yeah, that starts to hurt!


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PITTSBURG — Almost on cue, a collective gasp came from the Parkside Elementary School cafeteria.
Second-graders Damilare Aguda and Aaliyah Mercado were among the dozens of students sitting cross-legged on the floor who let out a loud “ohhhh” Wednesday morning when a ballet dancer with a large wolf head quickly vaulted from behind the curtain onto the stage during a performance of selected scenes from “The Nutcracker.”
“It was awesome,” Aguda said. Though her friends liked the sugarplum fairy, Mercado insisted that the wolf was her favorite character.
The reactions meant a lot to the dancers of the Pittsburg-based Black Diamond Ballet Theater, which bills itself as the first professional ballet company in East Contra Costa County. Later this month, the company will perform “The Nutcracker” at the Pittsburg Creative Arts Building, 250 School St.
“It was very humbling. We’re so worried about the steps; it’s nice to be reminded by the audience how much they enjoy it. It’s cool and fun to be a part of,” associate director Sharon Sobel said.
After performing, company members talked about how taken aback they were, she said.
The company also handed out free tickets for their upcoming “Nutcracker” performances to students and staff at Parkside as a reward for the school’s improved test scores.
Black Diamond Ballet Theater was formed in May after artistic director Michael Lowe parted ways with Peninsula Ballet Theater, which previously had performed “The Nutcracker” in Pittsburg. Black Diamond includes 15 professionals and two apprentices.
Lowe’s relationship with the board of the Creative Arts Building and the available space for rehearsals led to the creation of the company.
“There are a lot of resources and a lot of good talent. We felt we could make something out here,” Lowe said.
Pittsburg natives Sarah Hernandez and Ricky Navarro, who play Clara and The Nutcracker, said the company gives East Bay kids a means to perform without having to go to bigger cities as they did. About 40 local teen dancers participate in the ballet.
“A lot of people believe in the final product, and bringing the arts to a community that might not go into a city to see it,” said Sobel, who is also president of the Creative Arts Building board and owns an Antioch ballet school.
Black Diamond strives be more “up close and personal with the community” than a touring company, Sobel said. The company plans to visit five more area schools before performing Dec. 18 to 20.
Paul Burgarino can be reached at 925-779-7164.


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domain: entertainment


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The short perioperative period, spanning several days pre- and postsurgery, is now believed to have a nonproportionally large impact on long-term cancer outcomes (1,2). Numerous physiological responses to the newly discovered cancer and to surgical resection trigger pro-metastatic processes that can affect minimal residual disease (MRD; single tumor cells/micrometastases). MRD can potentially seed into new organs, escape from dormancy, and/or accelerate its growth, eventually becoming life threatening. Underlying processes for such surgery-induced deleterious effects include 1) immune suppression, 2) excessive shedding/spreading of tumor cells, 3) systemic release of growth factors (3), and 4) numerous direct pro-metastatic effects of stress and inflammatory mediators on MRD, increasing its proliferation, migration, and invasion capacity, as well as MRD release of pro-angiogenic and pro-growth factors (4,5). These multiple processes occur simultaneously during the perioperative period and act synergistically to facilitate metastatic progression. On the other hand, the removal of the primary tumor diminishes several ongoing metastasis-driving processes (5). Thus, a new and delicate balance between pro- and antimetastatic processes is created perioperatively, which may determine whether MRD will erupt postoperatively or will regress to dormancy—two opposing processes that are each self-perpetuating and bear long-term critical ramifications (5). Therefore, the perioperative period should be exploited therapeutically to achieve an antimetastatic balance, before pro-metastatic processes prevail irreversibly (1). Nevertheless, there are obstacles to employing common antimetastatic interventions during the perioperative period. Chemo- and radiotherapies prevent tissue healing and cause immune suppression, and immunotherapies often cause adverse and/or pyrogenic effects that are indistinguishable from signs of infection. Thus, these treatments are not given close to surgery. However, in past years, our group and others have found that prominent mediators of the pro-metastatic effects of stress and surgery are catecholamines (epinephrine and norepinephrine) and prostaglandins, secreted perioperatively in response to stress and tissue damage (1,4,6). These responses can be safely and effectively mitigated through simple pharmacological interventions. Indeed, in translational studies, using six tumor models of metastatic progression, we showed that β-adrenergic blockade (using propranolol/nadolol) and/or COX2 inhibition (using nonsteroidal anti-inflammatory drugs [NSAIDs], including etodolac), reduced the metastasis-promoting effects of surgical stress (1,7–10). In studies that involved major surgeries and/or excision of a spontaneously metastasizing primary tumor, only the combined blockade, employing propranolol and etodolac, was robustly effective in reducing metastasis and improving survival rates (7,8). Recently we concluded two small prospective phase II biomarker clinical trials, treating breast and colorectal cancer patients with propranolol and etodolac for a few weeks, initiating treatment five days before surgery. This therapeutic intervention was proven safe in both studies (11,12). By analyzing biomarkers in the excised primary tumors and in repeated blood samples, we found that the treatment positively affected tumor epithelial-to-mesenchymal transition (EMT) and the composition of tumor-associated leukocytes. In breast cancer, treated patients also demonstrated reduced tumor Ki67 expression, reduced tumor GATA-1, NFkB, and STAT-3 transcriptional activity, and reduced serum levels of IL-6 and CRP and their up- and downstream transcriptional pathways. These are promising multiple indications of the antimetastatic effects of this perioperative drug intervention (11,12). Missing, however, are long-term cancer outcomes, which necessitate larger clinical trials with long-term follow-up. In this issue of the Journal, Desmedt et al. report an association between intraoperative use of the COX inhibitor ketorolac in breast cancer patients and reduced rates of early metastases (13). This observation corresponds well with animal studies employing various NSAIDs perioperatively (14–16), and with our abovementioned clinical trial in breast cancer patients (12). Although only associative, the findings of Desmedt et al. support the clinical benefits demonstrated in the above prospective clinical trials and contribute to the expanding oncologic literature of perioperative NSAID use (17). Intriguing is the equivalence in overall recurrence incidence reached at 96 months postoperatively, which suggests that intra-operative ketorolac induced (or maintained) a state of dormancy in preexisting micrometastases; however, after several years, these foci may escape dormancy. The findings also indicate that although a statistically significant effect of ketorolac was evident in the entire cohort studied (n = 827), it seems that patients with a body mass index (BMI) greater than 25 kg/m2 (n = 381) are most likely to benefit from this intervention, as it remained statistically significant in these patients alone, but not in those with a BMI lower than 25 kg/m2 (n = 446). Breast cancer patients with a BMI greater than 25 kg/m2 were reported to exhibit inflammation of mammary adipose tissue and higher systemic inflammatory status (18), and inflammation is a hallmark of cancer progression (19). Obese women were also found to have more profound stress and inflammatory responses to experimentally induced psychological stress (20). Thus, ketorolac can be expected to have greater efficacy in this susceptible subpopulation. Importantly, prostaglandins have been shown to suppress NK activity in vivo (14) and to modulate the activation of NFkB, STAT3, and CREB, increasing expression of IL6, VEGF, IL8, and MMPs, all known to promote cancer progression (15). Thus, several mechanisms can mediate the beneficial effects of intra-operative use of ketorolac. The study by Desmedt et al. also reports that intra-operative use of diclofenac, a semiselective COX2 inhibitor, was not associated with reduced recurrence rates (n = 1007) (13). Important to note is that diclofenac and ketorolac were studied in noncomparable settings, including different institutions, patient cohorts, year periods, follow-up modalities, and doses. Additionally, each drug was uniquely associated with the specific characteristics of the patients who consumed it (eg, ketorolac with younger, lower BMI, smaller tumor size). Thus, while it is valid to suggest benefits for ketorolac based on statistical corrections for such known modulating factors, one should be cautious to suggest no effects for diclofenac under noncomparable conditions. Interestingly, the ongoing “Randomized European Celecoxib Trial” (REACT) reported no overall benefits for celecoxib (a selective COX2 inhibitor) at an average 60 months of follow-up, but potential benefits in subpopulations (21). Unfortunately, celecoxib treatment was initiated several weeks after surgery, thus not covering the critical perioperative period. Overall, perioperative interventions should be prospectively tested in cancer patients (ie, through randomized controlled trials), given that this period has a high impact on long-term cancer outcomes. Future interventions may include some forms of immunotherapies that have minimal adverse effects, systemic pharmacological or dietary anti-inflammatory and/or β-adrenergic inhibiting interventions, stress-reducing behavioral/psychological interventions, or combinations of such interventions, which may be most effective (1). Such approaches may transform the critical perioperative period from a high-risk time frame to an opportunity to arrest cancer progression or to eliminate MRD (1). Notes Affiliations of authors: Sagol School of Neuroscience (SBE), School of Psychological Sciences (SBE), Oncology Institute, Sheba Medical Center at Tel Hashomer (TG), and Sackler Faculty of Medicine (TG), Tel Aviv University, Tel Aviv, Israel. The authors have no conflicts of interest to declare. References 1 Horowitz M , Neeman E , Sharon E , Ben-Eliyahu S. Exploiting the critical perioperative period to improve long-term cancer outcomes . Nat Rev Clin Oncol. 2015 ; 12 4 : 213 – 226 . Google Scholar Crossref Search ADS PubMed 2 Hiller JG , Perry NJ , Poulogiannis G , Riedel B , Sloan EK. Perioperative events influence cancer recurrence risk after surgery . Nat Rev Clin Oncol. 2018 ; 15 4 : 205 – 218 . Google Scholar Crossref Search ADS PubMed 3 Neeman E , Ben-Eliyahu S. Surgery and stress promote cancer metastasis: New outlooks on perioperative mediating mechanisms and immune involvement . Brain Behav Immun. 2013 ; 30 ( Suppl ): S32 – S40 . Google Scholar Crossref Search ADS PubMed 4 Cole SW , Nagaraja AS , Lutgendorf SK , Green PA , Sood AK. Sympathetic nervous system regulation of the tumour microenvironment . Nat Rev Cancer. 2015 ; 15 9 : 563 – 572 . Google Scholar Crossref Search ADS PubMed 5 Haldar R , Ben-Eliyahu S. Reducing the risk of post-surgical cancer recurrence: A perioperative anti-inflammatory anti-stress approach . Fut Oncol. In press. 6 Neeman E , Zmora O , Ben-Eliyahu S. A new approach to reducing postsurgical cancer recurrence: Perioperative targeting of catecholamines and prostaglandins . Clin Cancer Res. 2012 ; 18 18 : 4895 – 4902 . Google Scholar Crossref Search ADS PubMed 7 Glasner A , Avraham R , Rosenne E , et al. . Improving survival rates in two models of spontaneous postoperative metastasis in mice by combined administration of a beta-adrenergic antagonist and a cyclooxygenase-2 inhibitor . J Immunol. 2010 ; 184 5 : 2449 – 2457 . Google Scholar Crossref Search ADS PubMed 8 Sorski L , Melamed R , Matzner P , et al. . Reducing liver metastases of colon cancer in the context of extensive and minor surgeries through beta-adrenoceptors blockade and COX2 inhibition . Brain Behav Immun. 2016 ; 58 : 91 – 98 . Google Scholar Crossref Search ADS PubMed 9 Benish M , Bartal I , Goldfarb Y , et al. . Perioperative use of beta-blockers and COX-2 inhibitors may improve immune competence and reduce the risk of tumor metastasis . Ann Surg Oncol. 2008 ; 15 7 : 2042 – 2052 . Google Scholar Crossref Search ADS PubMed 10 Inbar S , Neeman E , Avraham R , Benish M , Rosenne E , Ben-Eliyahu S. Do stress responses promote leukemia progression? An animal study suggesting a role for epinephrine and prostaglandin-E2 through reduced NK activity . PLoS One. 2011 ; 6 4 : e19246 . Google Scholar Crossref Search ADS PubMed 11 Haldar R , Ricon I , Cole S , Zmora O , Ben-Eliyahu S. Perioperative beta-adrenergic blockade and COX2 inhibition in colorectal cancer patients improves pro-metastatic indices in the excised tumor: EMT, tumor infiltrating lymphocytes (TILs), and gene regulatory pathways . Brain Behav Immun. 2017 ; 66 : e9 . Google Scholar Crossref Search ADS 12 Shaashua L , Shabat-Simon M , Haldar R , et al. . Perioperative COX-2 and beta-adrenergic blockade improves metastatic biomarkers in breast cancer patients in a phase-II randomized trial . Clin Cancer Res. 2017 ; 23 16 : 4651 – 4661 . Google Scholar Crossref Search ADS PubMed 13 Desmedt C , Demicheli R , Fornili M , et al. . Potential benefit of intra-operative administration of ketorolac on breast cancer recurrence according to the patient’s body mass index . J Natl Cancer Inst. 2018 ; 110 10 : 1115 – 1122 . 14 Yakar I , Melamed R , Shakhar G , et al. . Prostaglandin e(2) suppresses NK activity in vivo and promotes postoperative tumor metastasis in rats . Ann Surg Oncol. 2003 ; 10 4 : 469 – 479 . Google Scholar Crossref Search ADS PubMed 15 McCarty MF. A role for cAMP-driven transactivation of EGFR in cancer aggressiveness - therapeutic implications . Med Hypoth. 2014 ; 83 2 : 142 – 147 . Google Scholar Crossref Search ADS 16 Zhang S , Da L , Yang X , et al. . Celecoxib potentially inhibits metastasis of lung cancer promoted by surgery in mice, via suppression of the PGE2-modulated beta-catenin pathway . Toxicol Lett. 2014 ; 225 2 : 201 – 207 . Google Scholar Crossref Search ADS PubMed 17 Cata JP , Guerra CE , Chang GJ , Gottumukkala V , Joshi GP. Non-steroidal anti-inflammatory drugs in the oncological surgical population: Beneficial or harmful? A systematic review of the literature . Br J Anaesth. 2017 ; 119 4 : 750 – 764 . Google Scholar Crossref Search ADS PubMed 18 Vaysse C , Lomo J , Garred O , et al. . Inflammation of mammary adipose tissue occurs in overweight and obese patients exhibiting early-stage breast cancer . NPJ Breast Cancer. 2017 ; 3 : 19 . Google Scholar Crossref Search ADS PubMed 19 Hanahan D , Weinberg RA. Hallmarks of cancer: The next generation . Cell. 2011 ; 144 5 : 646 – 674 . Google Scholar Crossref Search ADS PubMed 20 Brydon L , Wright CE , O'Donnell K , Zachary I , Wardle J , Steptoe A. Stress-induced cytokine responses and central adiposity in young women . Int J Obesity. 2008 ; 32 3 : 443 – 450 . Google Scholar Crossref Search ADS 21 Coombes RC. A phase III multicentre double blind randomised trial of celecoxib versus placebo in primary breast cancer patients (REACT – Randomised EuropeAn Celecoxib Trial); 2018. http://www.cancernetwork.com/videos-breast-cancer/could-cox-2-inhibition-celecoxib-have-role-breast-cancer. © The Author(s) 2018. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: email@example.com. This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/about_us/legal/notices)
JNCI: Journal of the National Cancer Institute – Oxford University Press
Published: Oct 1, 2018
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domain: health


text:
Amber Heard detailed an alleged attack at the hands of Johnny Deppwhich she claims left her with a bloody lip -- an injury her lawyers tried to prove with a photo -- but were shot down by the judge because it wasn't submitted in time for trial ... but TMZ has the photo ... a photo Depp's press team says doesn't line up with the timing of her allegations.
Heard claimed in her testimony ... Johnny struck her in the mouth during an argument, saying, "I was in one of these fights, I believe it's this one, in his downtown ECB, we call it, loft, and we're in the kitchen living room area and he backhands me."
She continued, "And, you know, it was, you know, he wears a lot of rings. I remember kind of just feeling like my lip went into my teeth, and it got a little blood on the wall. Just that simple, a little bit of blood on the wall."
We've obtained the photo Heard says she took after the alleged incident, showing what looks like a cut on her lip, along with a note that reads, "I shall return xxx" ... a note she says Depp left behind.
It's the same photo Heard's legal team wanted to show the jury, but Depp's team objected ... saying Amber's lawyers never submitted the photo during the discovery phase of the case. The judge agreed with Depp's attorneys, so the photo was never introduced into evidence.
Now Depp's team tells TMZ ... the photo is from 2012 -- TMZ has seen the metadata and we've confirmed that -- yet in the UK defamation case, Amber's witness statement said the first violent incident was in 2013 ... a year after the alleged bloody lip photo was taken.
A source close to Amber says she messed up her dates in the UK case, and once she got her therapist records, it showed the alleged abuse from Johnny stemmed back to early 2012 ... so they say the timing of the photo makes sense.
Of course, the photo and alleged incident are just one example of countless physical violence claims both Heard and Depp have leveled against each other through the trial.
Remember, Johnny's team claimed Amber's allegations have evolved with "new and convenient details" over the years -- and that she had been "preparing to give the performance of her life in this trial."
To that, Amber's team says, "The panicked Depp's team is fighting tooth and nail to prevent compelling evidence and photos such as this from being introduced. They continue their losing strategy: distract the jury and demonize the defendant."
The case is in recess until May 16, when Amber is expected to be back on the stand.

domain: celebrity


text:
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The Belle- preppy plaid fabric shoe clip bows- fuchsia, orange, and teal. $20.00, via Etsy.
beautiful fall color and great layers for movement!
TARINA TARANTINO Baroque Metal Heart Skull Pendant

domain: design


text:
Defense Minister Davit Tevzadze admitted during a July 10 press conference that “a defeatist syndrome exists” in the Georgian army since last May’s fighting in Abkhazia. According to Tevzadze, this “purely psychological syndrome” is in the process of being overcome through more intensive troop training. (Russian agencies, July 10) Georgia’s political leadership in effect accepted military defeat in May by deciding to keep the army out of the fighting in Abkhazia.
Meanwhile in that region sporadic fighting continues, according to Maj. Gen. Haroum al-Rashid, head of the UN Mission of Military Observers in Georgia (UNOMIG). He announced yesterday that clashes between Abkhaz and Georgian armed groups and the mining of roads have forced UNOMIG to curtail patrolling in general, and to monitor the area of fighting from the air only. (Russian agencies, July 12)
COMMUNIST FRONT CREATED IN AZERBAIJAN.


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Micromax IN 2 India Price: The upcoming Micromax IN 2 smartphone’s key specs has been revealed forward of the cellphone’s launch in India. Not too way back, the Indian shopper electronics producer unveiled a reasonably priced smartphone in its residence nation. The Micromax IN Note 2 went official in India carrying a price ticket of INR 15,000. Despite costing much less, the phone got here with an AMOLED display, a triple rear camera setup, and a slew of different sufficiently good options.
Still using excessive on the success of its IN Note 2 smartphone, Micromax is reportedly prepping to launch one other smartphone dubbed Micromax IN 2 in India. Moreover, the handset will succeed the corporate’s well-received IN 1 series. The previous year, Micromax additionally launched the In 2b smartphone, which later acquired a notable low cost of INR 500 in India. It is at the moment unclear when the company will launch the brand new handset. However, the Micromax IN 2 smartphone’s specs has already been revealed earlier than launch.
Expected Micromax IN 2 Specifications
It is to be mentioned that Micromax remains to be mum on the precise launch date of the IN 2 smartphone. Nevertheless, the handset’s key specs and options have popped up on the web, courtesy of a Twitter consumer. Taking to his Twitter account, tech fanatic Ishant Raj leaked the whole specs sheet of the upcoming Micromax IN 2. The leaked specs counsel that the handset will include a 6.5-inch display. Given that it is going to be a price range provided, this may very well be an IPS LCD.
- the display will reportedly ship a refresh rate of 90Hz
- the display will reportedly supply a Full HD+ decision.
- the rear panel will home three cameras together with a 48MP predominant camera.
- the rear-mounted digicam setup will comprise a few 2MP cameras, which is more likely to embrace a macro lens.
- Upfront, the telephone will characteristic an 8MP shooter for capturing selfies and video calling.
As anticipated, the phone’s rear panel makes use of polycarbonate materials. A strong 5000 mAh battery will reportedly energy up the handset. Also, the tipster claims that the battery will help 18W quick charging. Under the hood, the telephone may pack a MediaTek Helio G88 SoC, which is out there within the Infinix Hot 11S and Redmi 10 Prime smartphones. Details concerning the telephone’s reminiscence configuration are nonetheless scarce. However, Micromax is more likely to launch a minimum of a 4GB RAM+64GB storage variant.
Micromax IN 2 India Price Expected
Aside from that, the telephone may include a microSD card to help reminiscence growth. Moreover, the expected Micromax IN 2 India Price someplace around INR 10,000 to INR 11,000. Other very important items of details about the upcoming IN 2 are more likely to floor online within the coming days.


text: 18 Karat Yellow Gold French Gate Dangle Earrings ,Tiffany designer, Thomas Kurilla created these . This is a series of earrings from my travels. Photographs of iron and bronze gates, fences,and windowgates. The lost art of decorative hand wrought metal work. These are sandblasted / satin because of the nature of the design.18ky. 22 mm x 14mm x 3mm deep without the hook.. Made to order, please allow 4 weeks for delivery. signed T. Kurilla , stamped 18k.


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KARACHI- Jul 14,2021 – Fourth wave of coronavirus hit the Sindh province of Pakistan where due to the rising number of cases, schools across the province have been closed once again.
This decision was taken at the meeting of the Provincial Covid-19 Task Force chaired by Sindh Chief Minister Murad Ali Shah.
It was decided at the meeting that schools across the province from class I to VIII would be closed from Friday, while educational institutions of class IX and above would also be closed except for examinations.
Indoor dinning and picnic spots
The meeting decided that indoor dining would be closed from coming night, amusement parks, water parks, sea view, Hawke’s Bay, Kenjhar Lake would be closed from Friday, while cinemas, indoor gyms and indoor sports would also be closed.
Rate of new corona cases
The Sindh Health Department informed the meeting that the rate of new corona cases in the province has reached 7.4%.
Expressing concern, Sindh Chief Minister Murad Ali Shah said that if the Corona cases have exceeded 5%, it is a dangerous situation.
During the meeting, Health Secretary Kazim Jatoi said that a total of 16,262 corona tests were conducted in the province out of which 1,201 cases were detected. At present, 837 patients are in hospitals, now most of the patients are in government hospitals.
Cases in Karachi
He said that the rate of new cases in Karachi was 17.11% on July 13.
According to the weekly report, 21% cases were reported in East District, 15% in South, 12% in Central and 8% in Korangi.
Expressing concern over the country’s largest city, Sindh Chief Minister Murad Ali Shah said that the situation in Karachi was very bad.
It was also informed in the meeting that so far 58,70,991 doses of Corona vaccine have been received across the province, while 44,65,908 doses have been used so far.
It may be noted that the number of corona virus patients in Sindh has once again increased to 349,586 from other provinces, while the total death toll has risen to 5,621.
Corona situation in Pakistan
Cases of Corona virus of Indian Delta variant have increased in Pakistan, the rate of positive corona cases in the country has gone above 4%.
Pakistan has reached the 30th position in the list of corona patients.
According to the National Command and Operations Center (NCOC), 1,980 more cases of corona virus have been reported in Pakistan in the last 24 hours, with 24 more people losing their lives in the face of this deadly epidemic. A further 738 corona patients recovered, while the positive case rate was 4.17%.
The total number of people dying from corona virus across the country has reached 22,642 while the total number of corona patients has reached 978,847.


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text:
Lady GaGa Poses Nude to Promote New Single Off 'ARTPOP'
Lady GaGa will release her new single, reportedly entitled "Applause", on August 19 and she wants to make sure her fans remember it. The 27-year-old singer shared a naked picture of her on Twitter and captioned it, "1ST SINGLE FROM ARTPOP COMES AUG.19 #24DAYS."
In the raunchy picture, GaGa is seen wearing nothing but a pair of bizarre spectacles and black high heels. Sitting on a futuristic throne built up of motherboards, GaGa shows off unicorn tattoo on her thigh and "ARTPOP" tattoo on her arm as she covers up her body.
Earlier this week, GaGa teased fans with a snapshot of what might be the lyrics of "Applause". GaGa also told fans that she would perform the song live at the MTV Video Music Awards on August 25 at Barclays Center in Brooklyn, New York. It will mark her first live performance after undergoing a hip surgery last February.
GaGa is currently working on her third studio album, "ARTPOP". It is set to drop on November 11 via Interscope Records.
More Lady GaGa News
- 'Logan' Producer Hints at X-23 Solo Movie
- Jamie Foxx Called 'Disrespectful' by Nyle DiMarco for Making Up Sign Language on 'Fallon'
- John Boyega Play in London Cut Short Due to Bomb Threat
- Joseph Duggar Engaged to Kendra Caldwell at His Sister Joy-Anna's Wedding
- Gregg Allman Dies After Battle With Liver Cancer, Ex-Wife Cher Mourns Him
- Watch a Preview of Halsey and Lauren Jauregui's 'Strangers' Video
- Beyonce Channels Michael Jackson in Throwback Photos
- Blac Chyna Licks Christina Milian's Boob in NSFW Pic


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text:
4 Fun Wedding Celebrants in the Shoalhaven
Looking for a fun wedding celebrant? Here's 3 non-boring celebrants that bring the fun & laughter to wedding ceremonies in the Shoalhaven and South Coast of NSW.
- Locations: Sydney, Shoalhaven, Southern Highlands
- Services: Weddings, Elopements, Legals Only, Surprise Weddings, MC
- Bio: Official party starter, Zoe is an upbeat, super fun officiant who delivers very personal, heartfelt ceremonies with plenty of hype and energy. Reviews typically state "most fun celebrant ever" and "guests were raving about her".
- Locations: Wollongong, South Coast, Southern Highlands
- Services: Weddings, MC
- Bio: Delivers fun & personalised ceremonies in a calmer style than some of the more energetic celebrants on this list. Couples love how helpful, organised and easy to work with that Sharon is.
- Locations: South Coast, Southern Highlands
- Services: Weddings, Elopements, Legals Only, Vow Renewals, MC
- Bio: Fun radio personality who delivers light hearted, romantic wedding ceremonies with plenty of laughs. Adam has a cheeky sense of humour and is a calming influence on the wedding day.


text:
The Team of the Year is out!
The guessing over! EA Sports has announced the Team of the Year.
Beside the lineup for the Team of the Year also the first ratings of the cards were announced. In the Ultimate Team mode of FIFA 21 the TOTY cards of the strikers will be available first. With a little luck, they could be in your packs since today, at 19 o'clock. You can look forward to strong cards of Cristiano Ronaldo, Robert Lewandowski and Kylian Mbappé. CR7 and Robert Lewandowski will both receive a card with an OVR of 98, while Kylian Mbappe has an overall rating of 97.
On the other hand, another is missing from the forward line of the TOTY. Lionel Messi. The superstar of FC Barcelona apparently could not convince the community and has not found a place in the Team of the Year.
How long the packs of the strikers will be available in the game is not yet known. Likewise, it can only be speculated which team parts will be available in the packs next.
In the midfield of the TOTY, two professionals from Manchester as well as Bayern star Joshua Kimmich could be available. Kimmich is joined in the eleven by Manchester United's Bruno Fernandes and Manchester City's Kevin de Bruyne.
The defence also features an FC Bayern Munich player. Alphonso Davies could make the cut. Furthermore, the backline is quite prominent. Davies' colleagues are Sergio Ramos from Real Madrid and Virgil van Dijk and Trent Alexander Arnold from Liverpool FC.
The TOTY is compiled by Bayern goalkeeper Manuel Neuer. The German national goalkeeper could unsurprisingly secure a place in the team.
- Manuel Neuer, FC Bayern Defence:
- Alphonso Davies, FC Bayern
- Sergio Ramos, Real Madrid
- Virgil van Dijk, Liverpool FC -
Trent Alexander-Arnold, Liverpool FC
- Joshua Kimmich, FC Bayern
- Kevin de Bruyne, Manchester City
- Bruno Fernandes, Manchester United
- Cristiano Ronaldo, 98, Juventus Turin/Piemonte Calcio
- Robert Lewandowski, 98, FC Bayern
- Kylian Mbappé, 97, Paris Saint-Germain


text:
A BRAVE road accident victim says she is humbled and very grateful for the tide of community support she is receiving in the battle to rebuild her life.
Carol Forshaw, 36, lost her right leg when her motorbike collided with a car on a rural road in Northumberland more than three years ago.
After claiming the NHS failed to provide her with a properly-fitting prosthetic limb which would allow her to get on with her life, she decided to raise £26,000 and buy one herself.
Now Carol, who lives in Stakeford, Northumberland, has revealed she is just £3,000 short of her target, thanks to fantastic fundraising support from family, friends, neighbours and people she had never even met before.
Yesterday, Carol and her mother Ibby turned out to see off a dozen people from the Guide Post and Stakeford area on a five-mile sponsored walk along part of Hadrian’s Wall to boost her fundraising appeal.
The group are all former classmates at a local school who decided to raise money for charity each year following a reunion, and chose Carol as this year’s recipient.
In addition, the Ashington and District Male Voice choir is holding a special concert next month to provide a further boost for the campaign.
It has been arranged at the suggestion of Malcolm Corbett, a member of both the choir and the church, who knows Carol and her family.
The latest events follow months of fundraising by many local people and organisations who have been touched after her plight was revealed by the Chronicle.
In two weeks’ time, Carol is due to have an operation at Newcastle’s RVI on the stump of her right leg, to put muscle back on the bone and make it easier to have a prosthetic leg fitted.
She said: “While I’m recovering from that operation I’ll be thinking of other things I can do to get to that £26,000, because I’m a positive thinking person and I’m not going back down the road of having an unsuitable limb again.
“I feel very humbled and extremely grateful for all the support I’ve had and the way people have been chipping in to help and do what they can.
“There has been a brilliant sense of community and it is very touching for me and my family. I am so thankful to everyone because there have been do many people just raising £20 or £30 here and there.
“The Junction Cafe at Stakeford Methodist Church has been great at holding events for me, my work colleagues did a coast-to-coast bike ride in May, my friend Carol Prior completed a 26-mile roller skating marathon in Brighton and a lady called Elaine Scott organised today’s walk along Hadrian’s Wall.
“A local woman even did a tea leaf reading at my mum’s house recently, the Ashington Lionesses donated £200 and the local Rotary Club has helped as well. It has been lovely and very heartening.
“The fund has now reached £23,000 and it’s taken me three years to get that far. It has been really hard but all this fundraising has really boosted things lately. A lot of people didn’t realise that prosthetic legs cost so much.
“Once I get the leg fitted, which will be at a hospital in Dorset, I know that in five years’ time it will have to be replaced, and that could mean finding at least another £26,000.”
The Ashington Male Voice Choir concert, which also features Newcastle-based youth choir Harmony, will be held in Stakeford Methodist Church on Saturday October 22 from 7pm. Tickets cost £6 and are available from Malcolm Corbett on 01670 818714.
Choir chairman Bob Brind said: “We are delighted that we can do something to help Carol. Tickets cost £6 and there are no overheads so we hope to raise several hundreds of pounds for her. We hope the night will be a sell out.”
Carol lost her right leg in July 2008 after her motorbike collided with an oncoming car at Cragside near Rothbury. The accident resulted in her losing all of the skin and tissue down to the bone. She was flown by the Great North Air Ambulance to Newcastle General Hospital for a lifesaving total blood transfusion.
She decided to raise the funds to buy her own prosthetic limb after claiming the NHS couldn’t provide her with an appropriate one.
Anyone wishing to help can email Carol at email@example.com


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Recent Highlights from the IFLA Preservation and Conservation (PAC) Centres
22 апреля 2024
What are IFLA PAC Centres?
IFLA’s PAC Centres are hubs of knowledge for documentary heritage preservation and access – hosted in major institutions around the world. PAC Centres take initiative to identify and raise awareness of preservation and conservation issues within the library field.
Some areas on which PAC Centres focus their work include:
- Building relationships with national and regional authorities responsible for heritage collections, as well as the wider community, to increase understanding and support
- Working to identify and promote best practices and share information, examples, and specialist expertise that are relevant to practitioners at the local, regional, and international levels
- Assisting in disaster response efforts on which local/regional support and expert advise are needed
Through this network, they engage with IFLA HQ and with other PAC Centres to assist in capacity building and share information relevant to the global library field.
PAC Centre Highlights
Every year, PAC Centres provide a report of their activities in these areas and beyond. As we look ahead to a new year, we are delighted to celebrate just some of the activities carried out by IFLA PAC Centres over the past reporting period (2021-2022)!
Leading awareness raising activities
The National Library of Australia’s Collection Care, Digital Preservation and Social Media teams joined forces to take part in International Ask a Conservator Day and World Digital Preservation Day. The day resulted in more than 20 unique questions across all social media platforms, with 18,164 impressions and 268 engagements and great engagement on Twitter. Read more here.
Similarly, PAC North America, hosted at the Library of Congress organises an annual Preservation Week. In 2022, they hosted a number of webinars exploring projects being undertaken at the library. Watch recordings of the Preservation Week 2022 webinars here: https://www.loc.gov/preservation/outreach/presweek/index_presweek.html
PAC Qatar, hosted by Qatar National Library, created an educational video series on preservation and conservation, offering an introduction to the disciple and to the IFLA PAC Network in English and Arabic. You can watch and share this video series on YouTube: QNL Educational Preservation and Conservation Series.
PAC Qatar also participated in broader celebrations of culture. As Doha was named the Capital of Culture in the Islamic World for 2021, PAC Qatar organised a webinar on the important role of libraries in preserving Islamic cultural heritage, in collaboration with the Islamic World Organisation for Education, Science, and Culture (ISESCO) and the Qatari Ministry of Culture and Sports. Watch here in English and in Arabic.
Sharing expert information and advice
PAC Centres identify key topics in the field of documentary heritage preservation and conservation and provide information to raise awareness and build capacity in these areas.
The National Diet Library of Japan’s 32nd Preservation Forum covered the theme “Disaster preparedness for library materials”. This Forum included trainings and discussion on topics such as dealing with water-damaged materials. More information can be found here.
Digitisation / Digital Preservation
Throughout 2022, the IFLA PAC Centre hosted at the National Library of Poland offered a series of ten webinars which explored different aspects of carrying out digitisation projects. These webinars provide information to libraries and other institutions who are at the very early stages of implementing a digitisation strategy, or who want to improve on their ongoing projects.
Topics include strategic approaches to project planning, budgeting and designing workflows, technical basics for digital preservation, and more.
Find all of the webinars here: IFLA PAC Open Webinars on Digitisation.
Responding to emergencies and countering trafficking
Following the outbreak of war in Ukraine in 2022, PAC Poland and the National Library of Poland provided support to Ukrainian institutions at their request.
PAC Qatar launched an observatory of the documentary heritage situation in the MENASA (Middle East, North Africa and South Asia) region. For key countries, this observatory will follow the political context, legal situation and cultural heritage protection laws, and the state of preservation of heritage collections. It will make note of key contacts and stakeholders, catalogues of documentary heritage collections, and other references that are important for decision-making regarding at-risk documentary heritage and emergency response.
For an example of emergency response, PAC Qatar engaged stakeholders such as ambassadors and special representatives in a meeting on Afghan heritage protection. The PAC Centre is involved in projects with partners such as the Alliance for the Restoration of Cultural Heritage (ARCH) to share information on looting and trafficking of cultural property and monitor the evolving situation in Afghanistan.
PAC Qatar also continues the Himaya Project, which launched in 2020 to counter the theft and illicit trafficking of documentary heritage in the region. In support of this project, they have organised webinars which have included a high-level panel discussion, an online conference, and an e-course on art trafficking with a focus on manuscripts. They are further developing a project with the Qatar Computer Research Institute to use a content management system to aggregate and better monitor web postings relating to the sale of manuscripts and other articles.
Building Local and Regional Capacity
IFLA PAC Centres work with institutions and other stakeholders involved in preservation and conservation at a national and regional level to share information and expertise targeting regional context and challenges.
For example, PAC Sri Lanka, hosted by the National Library and Documentation Service Board of Sri Lanka engaged a wide range of stakeholders in lectures and workshops. These included a workshop on palm leaf manuscripts offered for Buddhist monks, a lecture on conservation and preservation for prison rehabilitation officers across the country, and a workshop on Conservation and Preservation for government officers.
The PAC Centre hosted at the National Library of Kazakhstan maintains a close relationship with the National Libraries of Kyrgyzstan, Uzbekistan, Tajikistan, as well as other regional organizations involved in the preservation and preservation of documentary heritage. They host regular knowledge exchange meetings, such as a master class on restoring and repairing Central Asian book bindings.
PAC Centres in East Asia also have maintained a relationship with one another, with the directors of directors of the PAC Centres hosted at the National Library of China and National Library of Korea joining the National Diet Library for an online information-exchange and coordination meeting. Read more here.
Qatar National Library carried out a number of projects in the MENA region to support preservation and conservation in memory institutions. In particular, the library worked with the Sudan National Archives and Sudan House of Heritage on two projects to support the preservation and digitisation of heritage in the Arab region. Activities included training for staff and carrying out digitisation and awareness raising projects.
They have further engaged in activities aimed at preserving the audio-visual heritage of the MENA region, including with partners from the Sudan Institute of African and Asian Studies and the International Association of Sound and Audiovisual Archives (IASA).
Developing New Materials and Resources
As a part of their work to share knowledge, PAC Centres use their expertise to develop new resources that can be beneficial both for professionals in their countries and regions, as well as for practitioners around the world.
Over the previous years, PAC South Africa, hosted at the National Library of South Africa, has created preservation and conversation procedure manuals, a procedure manual for the digitisation of documentary heritage collections, and guidelines on topics such as deacidification, bookbinding, and book repair.
The National Library of Poland’s 10-webinar series on carrying out digitisation projects is an excellent example of an output that will act as a helpful resource for libraries of all sizes and levels of capacity.
PAC Sri Lanka has used their specific expertise on pest and insect control to develop and publish guidelines on managing insects and pests in libraries and archives in Sri Lanka, with the assistance of the Conservation and Preservation Advisory Committee of National Library of Sri Lanka.
PAC Japan developed a new training video on disaster preparedness for library materials, which was released on the NDL’s YouTube channel in 2022.
A number of the National Library of Australia’s preservation policies and guidelines were developed over the past 1-1/2 years, including their Collection Care and Preservation policy, the Physical Collection Emergency Response Procedures, and the Illumination of Collection Item on Display policy. The next step to be carried out by the PAC Centre is to make these documents available to access externally for reference.
Engaging with National, Regional and International Partners
A great example of how PAC Centres can engage with partners can be found in PAC Sri Lanka’s work on the UNESCO Memory of the World programme. In 2022, the centre worked with national institutions to prepare nominations of important Sri Lankan documents for the UNESCO Memory of the World International Register, including working on a joint nomination, which requires international cooperation.
PAC Kazakhstan has built strong ties with colleagues in Uzbekistan and conducted joint classes on ink research in manuscripts. The centre also provides support for publishing articles by restorers from other countries in the magazine published in the National Library of the Republic of Kazakhstan.
PAC South Africa maintains relationships with colleagues in Botswana, Namibia, Lesotho, Swaziland, Zimbabwe, Zambia, Malawi, Tanzania, Uganda, and Kenya, Mozambique, and Angola. Activities in this regard have included workshops on digitisation in Nairobi, and assistance provided to the National Archives and Library of Swaziland with the digitisation of Swaziland historical newspapers.
PAC Japan is active in networks related to national emergency response, such as the Executive Council of Japanese Cultural Heritage Disaster Risk Mitigation Network, which comprises of members of the former Cultural Property Rescue Program for areas affected by the 2011 Great East Japan Earthquake.
PAC Sri Lanka, Kazakhstan, and Australia joined a number of IFLA’s experts and volunteers from the Asia-Oceania region for a Regional Workshop held in Bangkok, Thailand in November 2022. Directors of these PAC Centres spoke with representatives of the Culture and Communication and Information Sectors of UNESCO Bangkok to share how the work of their PAC Centres and identify opportunities for future cooperation.
Finally, several PAC Centre directors attended the World Library and Information Congress (WLIC) 2022 in Dublin, Ireland in July 2022. This forum provided an opportunity to engage with one another, as well as with other relevant IFLA committees, including the Advisory Committee on Cultural Heritage and the Regional Council. These opportunities for exchange across IFLA’s network help to integrate cultural heritage preservation and access, including regional contexts, challenges, and opportunities, into the work of IFLA at the international level.
Stay tuned in 2023 for more updates from the PAC Centre network. Find out more about the network, including how to get in touch with each PAC Centre, here: IFLA PAC Centre Network.
Contact IFLA HQ with questions: firstname.lastname@example.org

domain: library


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Your email address will not be published. Epic Battle Music. Dog Whistle Sound. Halloween Doorbell. Sound Effects. Roland TR Beat bpm Pigeons Sound Effect. Necessary cookies are absolutely essential for the website to function properly.
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Keith Rodinelli, aspiring filmaker, composer, designer, and musician, generously contributed this album for re-release on Earstroke. Tonepoems dreamy melodies, imaginative storytelling, and graceful use of instrumentation puts Abandoned Amusements in a class of its own. Related Music Beta question-dark Versions - Different performances of the song by the same artist Compilations - Other albums which feature this performance of the song Covers - Performances of a song with the same name by different artists.
Reviewer: zachkayak - favorite favorite favorite favorite - February 11, Subject: real nice Not as disconnected as much of the other electronic Sparkle Motion - Tonepoem - Abandoned Amusements (File material I listen to on the archive. Nice tones, melodies are not shunned, creates sense of mood, yet maintains creative off beat details.
At the Rec Room.
Μαρίνα - Κωνσταντίνος Δρακωνάκης - Μαρίνα (CD), Suppression Disorder Part 5, Como Cantaba Mi Viejo - Carlos Miranda (4) - Deliciosa Y Caliente (Vinyl, LP, Album), 遊星からの物体X (album ver.) = The Thing From Another World - 俺はこんなもんじゃない* - 俺はこんなもんじゃない (CD, Album), Pose Ton Gun - Suprême NTM - Suprême NTM (CD, Album), Non Son Degno Di Te - Gianni Morandi - Gianni Morandi (Vinyl, LP, Album), Beau Coco - Les Chakachas* - Beau Coco / Eso Es El Amor (Shellac), Days Of Wonder - The Wallflowers - Rebel, Sweetheart (CD, Album)

domain: artistic


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Let's be clear: the state of panic and fear that gripped Wall Street and markets around the world this week was a creature of Washington's and Wall Street's own making.
After 30 years of deregulation, begun under the Nixon Administration, rapidly accelerated under the Reagan Administration and au courant ever since, we have witnessed the energy crisis of the late 1970s, the stock market crash of 1987, the savings-and-loan crisis of the late 1980s and early 1990s, the tech bubble of the late 1990s, the housing bubble as well as the derivatives scandal of the 21st Century to name just a few casualties of financial insanity and greed.
Deregulation has not been confined only to the financial sector: it has been rigorously applied to elections law, telecommunications, airlines, railroads, trucking, and a host of other sectors.
Deregulation is/was part of the ideological core of the modern conservative movement: its champions were from the University of Chicago School of Economics. They were influenced by the Austrian School that included the likes of Ludwig von Mises and Friedrich von Hayek and their followers, such as former Fed Chair, Alan Greenspan , and the economist, Milton Friedman. It complemented Republican principles of small government, laissez-faire capitalism, free markets, trickle down economics (or voodoo economics as George H. W. Bush once called it), lower taxes on the superwealthy, and elevation of private interests over and above the public good.
The idea of deregulation was that government need not regulate private business because greed, corruption, lack of innovation, selfishness, and the other aspects of human nature's darker side would be self-corrected in the market by an "invisible hand," a mechanism whereby markets adjust to imbalances, excesses, and imperfections through the corrective operation of a rational market system.
The invisible hand is in ordinary parlance a fiction. It is a metaphor. In reality, it does not exist for if it did it would not be invisible. It is a human creation; it exists in nature no more than faeries or goblins exist.
The meltdown on Wall Street and throughout the global financial system has killed the notion of laissez-faire capitalism and free markets at the moment. Unrestrained corruption and vice which ruled Wall Street (and Washington) and was championed by conservative ideologues from across the political spectrum have learned this week that we are playing a different game, that the old rules will no longer suffice if we intend to conserve the way of life and the principles on which America was built by its Founding Fathers.
By any honest interpretation of laissez-faire capitalism, free market theory, small government ideology, and deregulatory philosophy, the businesses that have been engaged in greed and corruption ought to be allowed to fail, their corporate officers and representatives tried and, if convicted, imprisoned and fined, and corporate assets sold to reimburse cheated consumers.
The government's response so far has been to bail out (Bear Stearns, Fannie Mae, Freddie Mac), let fail (Lehmans), and bail out (AIG). Inconsistent and not reassuring. The taxpayer funded bail outs have left ordinary Americans with an unpayable bill backed by largely worthless corporate assets. Even the assets that have some sale value will not cover the total bill.
Predatory and criminal practices, according to this ideology, are not rewarded by the capital system: markets can only operate rationally when a good or service is exchanged at a fair cost (i.e. market price).
What we have witnessed instead, is a changing of the rules of the game, to exonerate the guilty, and punish the aggrieved, ignorant, and vulnerable, through the most massive government intervention, led by a Republican administration, in United States history by either political party.
Now in a climate of panic and fear, the Congress is urged to hastily rush through its halls a complex and costly legislative program ill-suited to the function, nature, and purpose of the Congress.
The House of Representatives in our system of government was created to represent the popular interest. In other words, its elected representatives are to propose legislation based on spirited debate that reflects the people's interests, not Wall Street nor Washington special interests.
The US Senate in our system of government was created to give the states an equal voice in the passing of laws. It is supposed to be a purposefully weighty, deliberative, more thoughtful, body than its Capitol counterpart, the House. Through careful deliberation and lengthy debate, the Senate acts to temper the popular passions of the House. It is a body where compromise and wisdom is supposed to mend public opinion with sound policy to fashion legislation in the national interest.
There are three recent examples of legislation passed in a climate of panic and fear: authorization granting the president powers to invade Iraq, the USA Patriot Act, and the Homeland Security Act.
That is worth remembering as the US Congress, the American people, and the economy face very dark days indeed.


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Three Tips of the day!
The lowly printable coloring page is really a chance to show kids a lot of things about the world and best of all you can find coloring pages on just about every theme and idea and they are often free to print out. Printable coloring pages even work well in a pinch. If you have a bunch of kids over and only one unused coloring book left, it's easy enough to go online and print out as many copies of coloring pages as you need.
oloring Pages are a great low cost and quick to set up activity for your kids to take part in. For example if your little darling declares that they want to do so, you just fire up the PC and internet connection, browse to a coloring page site and print out some pictures.
Given how commercially successful the Winnie the Pooh franchise has became (having reached cult status across the globe) this has meant that the supply of Winnie the Pooh coloring pages is also very easily accessible which in turn means that they are pretty cheap as well. If you really want to drive the costs associated with the purchase of Winnie the Pooh coloring pages then you will be glad to learn that there are a number of Winnie the Pooh coloring pages available over the internet. These electronic Winnie the Pooh coloring pages work in precisely the same manner as their hardcopy, physical peers in that the child is required to color them in.

domain: hobby


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June 10, 2020
In February, EvergreenHealth Medical Center was the first U.S. hospital to report a COVID-19 death, and subsequently received a lot of patients with the virus from the assisted-living facility Life Care Center of Kirkland.
Kevin Kajita, director of support services for the Kirkland hospital, said the hospital adapted 134 rooms so that potentially contaminated air stayed put and did not go into the corridors.
It did so by changing the controls on the HVAC system to draw air from the corridors into the rooms, where it was then exhausted out, said Garett Buckingham, director of design and construction with EvergreenHealth.
The hospital at 12040 N.E. 128th St. already had designed in the ability to transition 24 rooms in the Silver Tower on its campus to so-called negative pressure rooms in reaction to an earlier severe acute respiratory syndrome (SARS) epidemic, and still has those, he said. As the need has lessened from the COVID-19 surge, the other 110 rooms have been converted back to their original state.
In light of ongoing pandemic and its experience with SARS, EvergreenHealth is in the process of altering the design for a 20-bed critical care unit (CCU) it plans for the Silver Tower. The change in the scope of construction will go before its Board of Commissioners June 16, and construction is expected to start mid-month, Buckingham said.
The redesign allows EvergreenHealth to convert 16 traditional patient rooms in the CCU to negative pressure rooms when needed, said Chris Rubright, director of medical planning and a health care principal for San Francisco-based KMD Architects.
KMD is the architect and interior designer on the CCU, which will be built on a floor that is now shelled space. Notkin Mechanical Engineers, now owned by P2S, provided mechanical and plumbing design. Aldrich & Associates is the general contractor.
Rubright said EvergreenHealth had the KMD Seattle office where he works begin redesigning the mechanical system before contract negotiations were done for a construction bid that went out in February. The unit will also have four airborne infectious isolation patient rooms, also negative pressure, that will share anteroom buffer space as added insurance that contaminants don't get into the corridors.
Buckingham, with EvergreenHealth, said converting traditional patient rooms that have not been designed for it to negative pressure uses more energy and is more labor intensive than having rooms already set up for it, as they will be in the CCU.
He said the unit's redesign adds two new exhaust fans, rather than using the hospital's existing system, so Evergreen can make more rooms elsewhere in the hospital negative pressure if needed.
The CCU is estimated to cost $26.6 million, excluding the redesign of the mechanical system.
“It will allow us to serve the community around us whether it be a surge in COVID-19 or another pandemic issue,” said Buckingham.
During normal operations, traditional patient rooms would have a minimum of six air changes per hour (ACH), Rubright said, and maintain neutral or slightly negative air pressure relative to the corridor. The four isolation rooms would have a minimum of 12 ACH. In isolation mode, the other 16 patient rooms would also go to 12 ACH.
The KMD design has the contaminated air exhausted into HEPA filters, which trap the contaminants, including bacteria and viruses. As additional protection, ultraviolet light in the filtration system sterilizes particles.
People in negative pressure rooms may have multiple or more serious health conditions, such as diabetes and high blood pressure and weakened immune systems, that make them more susceptible to something like COVID-19, he said.
Patient rooms that can be converted to negative pressure cost less to build and take up less space (given the anterooms) than airborne infectious isolation rooms, he said.
The project team for the critical care unit also includes Lund Opsahl, structural engineering; Stantec, electrical and acoustic design; DIRTT, modular partition system; Wilson Jones Commissioning; and Dowl, civil engineering.
In San Francisco, KMD said it played a smaller role in assisting University of California San Francisco Health to complete Phase 1 of a 53-bed respiratory isolation unit to serve COVID and non-COVID patients. The firm said that, working rapidly and under an existing contract for other services, it provided planning support so 13 acute- and critical-care beds at its Mount Zion Hospital could open April 28. This is UCSF Health's primary site for caring for patients with novel coronavirus.
Fifty-five percent of KMD's work is health care design.
In light of the COVID-19 pandemic, Rubright said he would expect more health care facilities to want the flexibility to switch some of their traditional patient rooms to negative pressure.
“It's a more cost-effective way of providing for that surge in patients,” he said.
Lynn Porter can be reached by email or by phone at (206) 622-8272.


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PATNA: Prime Minister Narendra Modi on Sunday said India’s standing has grown taller among Islamic countries in the world lately due to efforts by the NDA government he heads.
“For the first time in 50 years, India was invited to a summit of Islamic countries. In these 50 years, India had governments of Congress and its allies,” he said at an NDA rally in Bihar capital Patna, referring to the plenary of the foreign ministers’ conclave of Organisation of Islamic Cooperation (OIC), an influential grouping of 57 Islamic countries.
External Affairs Minister Sushma Swaraj attended the inaugural plenary of OIC as the guest of honour. OIC, the second largest inter-governmental organisation after the United Nations, had last invited India in 1969. There had been no invitation ever since as Pakistan had prevailed upon and got the invitations withdrawn every successive year.
In his address at the massive ‘Sankalp rally’ of NDA at Patna’s historic Gandhi Maidan, Modi blamed the previous Congress-led governments for making no effort towards ensuring that India is invited to the OIC summit.
“During the Saudi Crown Prince’s recent visit to Delhi, I asked him to raise the Haj quota from India as more and more Muslims want to go for Haj. He raised it to two lakh. This happened to no other country. India’s voice was heard and respected,” said Modi.
“I also told the Saudi Crown Prince about the plight of Indian immigrants who have been put in jails there for minor offences. The same evening he offered me sweets, saying he has decided to release 850 Indians from Saudi jails. I thank him with all my heart,” added the PM.
With Muslims comprising about 17 per cent of Bihar’s population and playing a crucial role in electoral outcomes, Modi’s speech is widely seen as an effort by the BJP-led NDA to woo the state’s minority community ahead of the Lok Sabha polls.
India’s largest Muslim-populated area after the Kashmir Valley and Lakshadweep happens to be Bihar’s Kishanganj district, where about 78 per cent of the population is Muslim.


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How food connects all the SDGs
Speaking at the Stockholm EAT Food Forum 13 June, centre director Johan Rockström and board member Pavav Sukhdev, pushed for a new way of viewing the economic, social and ecological aspects of the Sustainable Development Goals (SDGs).
The new illustration (see above, download high-res version here) is based on one of the iconic figures of the centre, “the wedding cake”, developed by centre science director Carl Folke and others. It implies that economies and societies are seen as embedded parts of the biosphere.
This model changes our paradigm for development, moving away from the current sectorial approach where social, economic, and ecological development are seen as separate parts. Now, we must transition toward a world logic where the economy serves society so that it evolves within the safe operating space of the planet.

domain: sociology


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In this webinar, we look at ‘hyperautomation’ trends that are transforming the healthcare sector. We further discuss a roadmap on how a healthcare organization can start its hyperautomation journey. We also discuss Robocare.AI, our healthcare automation platform
The number of cyberattacks on banks has seen a steep increase in the last few years. This webinar explores RBI-issued guidelines where it urges UCBs to have a robust cyber resilient framework to ensure security. It focuses on Cyber Security and Resilience, Cyber Security Operations Centre (C-SOC), and Cyber Security Incident Reporting.
This webinar explores the different cybersecurity threats that plague the healthcare sector. We explore various best practices that healthcare organizations can adopt to avoid security breaches.


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- 540 N Subway Blvd Map
- Route Nevada, MO 64772
- 540 N Subway Blvd, Nevada, MO 64772
- (417) 667-4581
54 Cafe can be found at 540 N Subway Blvd . The following is offered: Restaurants . In Nevada there are 11 other Restaurants. An overview can be found here.

domain: geography


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The Art Department provides an exciting environment in which all pupils can achieve their best. We have excellent facilities including an ICT suite and kiln. The curriculum offers a broad range of opportunities for pupils including: ceramics, animation, painting, wire sculpture and printing. Art offers pupils an experience to respond to the world in which we live, by developing their practical skills and understanding of artists and designers. We hope all pupils enjoy Art at Maiden Beech.
Module MapThis is the programme of learning over the academic year for this subject.
Pupils will learn about art form another culture (Aboriginal Art). They will make a series of artwork and build their knowledge of using paint, pencil work and printing. They will try styles such as dream time artwork and pointillism.
Pupils will learn about portraits and the proportions of the face. They will build their ability to using sketching pencils to create light and tone. Alongside this they will do a focus study on Picasso and create a portrait collage in the style of Picasso.
Pupils will study and draw natural forms and practice using a range of media including sketching pencils, colouring pencils, felt tips, oil pastels and paint. They will look at the Arts and Crafts movement and will make a William Morris style clay tile.
To learn about different elements of Art and using and adapting these skills when focusing on Mexican Art looking at 'The Day of the Dead' to create masks and clay sculptures. Pupils will be looking at proportion and scale to create detailed sketches of skulls!
Pupils will learn about colour theory and understand primary, secondary and tertiary colours and how to mix colours together using a colour wheel. They will study the art work of different artistic styles and artists and adapt them to their own work and designs.
To create a range of different styles of artwork using the seaside as a source of inspiration.
Pupils will learn about the 'rule of thumb' method for drawing figures. They will also create a self -portrait in the style of Grace Weaver. We will also be looking at skills like drawing hands and feet.
Pupils will look at Art from another culture, Indian Folk Art. They will create various Art forms
Pupils will learn about the Op Art movement. They will recreate works by Bridget Riley. They will learn to blend using coloured pencils. They will make a 3d box covered with Op Art designs of their choice.
|Autumn||Still Life and Perspective|
Pupils will learn to carefully observe 3d shapes. They will also learn how perspective I Art is used to create depth. The final outcome will be a Surrealist painting showing still life objects and perspectives.
Pupils will learn how Popular culture was depicted by artists in the 1960s. They will then produce a pop art montage, showing objects that are personal to them and reflect popular culture now. Pupils will also focus on how food is depicted in Pop Art.
|Summer||Trees and Landscapes|
Pupils will study trees in Art with a focus on the artist Gustav Klimt. Pupils will recreate the schools own 'meadow' in the style of Klimt. They will make observations using pencil sketches. They will make a mini Klimt 'Tree of Life' and they will have a choice of either making a Green Man tile or a Tree of Life tile.