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Peripheral Matters | BEST-CLI: A Critical Trial for Critical Limbs
Of the 8.5 million individuals with peripheral artery disease (PAD) in the U.S.,1 a small but substantial proportion have critical limb ischemia (CLI), the end-stage form of PAD characterized by ischemic rest pain or tissue loss.
Few other cardiovascular ailments carry a worse prognosis than CLI, where nearly half of patients die within two years of diagnosis, and a substantial proportion suffer limb loss.2 An aging population with associated cardiovascular risk factors is expected to further increase the prevalence of CLI in the near future.
Despite the morbidity and mortality risk conferred by CLI, quality evidence to guide clinicians on how to optimally treat patients with this condition has been strikingly meager. In particular, uncertainty remains regarding whether surgical or endovascular revascularization is the best modality to improve limb perfusion and mitigate amputation risk.
Moreover, medical therapy and revascularization procedures are provided to CLI patients by a variety of specialists across different disciplines – and variation in skillsets, biases and clinical acumen influence perceptions of what defines optimal CLI treatment. Thus, the CLI treatment landscape has traditionally been one characterized by opinion rather than robust data and well-defined treatment algorithms.
Though published more than a decade ago, the Bypass Versus Angioplasty in Severe Ischaemia of the Leg (BASIL) trial is the most emphasized study comparing revascularization strategies for CLI patients.3 This trial randomized 452 patients with infrainguinal disease and rest pain or tissue loss to surgical bypass or balloon angioplasty.
The primary endpoint, above-ankle amputation or death, was found to be similar between groups during long-term follow-up. Morbidity and early mortality was higher in the surgical arm, whereas a post-hoc analysis suggested benefit beyond two years in terms of amputation-free survival with surgery compared with angioplasty.
While representing perhaps the highest quality data for CLI revascularization strategies, BASIL had important limitations that limit the generalizability of its findings in modern CLI practice.3
Antiplatelet and cholesterol-lowering agents were used in approximately one-third of patients only – it is increasingly recognized that medical therapy and aggressive control of risk factors may reduce cardiovascular and limb events in the high-risk CLI population.4
Endovascular technologies and techniques have progressed, making even the most complex of lesions approachable and treatable. Many of these newer technologies have improved technical success rates and long-term patency.5 The endovascular technical failure rate of 20 percent reported in BASIL would be perceived as unusually high in a contemporary CLI cohort.6
In accordance with findings from BASIL, the ACC/American Heart Association guideline on PAD management recommends revascularization for all CLI patients to reduce limb loss. And it further suggests that decisions regarding revascularization be reached through interdisciplinary collaboration.7
Both endovascular and surgical revascularization are Class I recommended treatment options. Similarly, a recently published consensus statement by the Society of Vascular Surgery on CLI care endorses both modes of revascularization for most patient and anatomic subsets.8
As further data to guide contemporary treatment strategies have been desperately needed, the National Heart, Lung, and Blood Institute has funded the Best Endovascular Versus Best Surgical Therapy for Patients with Critical Limb Ischemia (BEST-CLI) trial, a prospective, randomized investigation involving approximately 120 sites situated in Canada and the U.S.9
The primary aim of BEST-CLI is to determine whether endovascular or surgical treatment achieves the best outcomes in patients with CLI and infrainguinal PAD. Enrollment began in August 2014 and is ongoing, with a total of 2,100 patients anticipated to participate. Eligible patients must have infrainguinal PAD that is deemed addressable with either surgery or endovascular techniques based on consensus by treating investigators.9
Importantly, in BEST-CLI, the definitive therapy within each revascularization arm is left to the discretion of the operator. For example, technologies such as stents, atherectomy and drug-coated devices may be employed for endovascular treatments as deemed appropriate by the treating physician.
The primary endpoint is major adverse limb event (MALE)-free survival, where MALE is defined as above-ankle amputation or major reintervention (e.g., new bypass graft, graft revision or thrombectomy/thrombolysis).
In addition to its pragmatic design whereby modern endovascular therapies are permitted and treatment strategies are left to the opinion and experience of individual operators, BEST-CLI has integrated cost-effectiveness and quality-of-life analyses that will add further insight into the impact of revascularization strategies on patient-oriented outcomes and health care economics.9
Best-CLI, since its infancy, has encouraged a multidisciplinary approach to CLI treatment, and site investigators comprise a diverse array of specialists in vascular medicine, interventional radiology, interventional cardiology and vascular surgery.
BEST-CLI will provide novel, high-quality evidence that guides clinicians in formulating best revascularization strategies for patients with limb-threatening disease. This should naturally translate to improved clinical outcomes. But beyond answering the important question of which revascularization strategy is optimal in CLI patients with both endovascular and surgical options, the trial has already been influential in other regards.
Awareness of the CLI epidemic has been improved through the conduct of a large, multinational trial aimed at a previously understudied and undertreated population.
BEST-CLI has also fostered multidisciplinary teamwork among specialists who previously may have competed rather than collaborated in the CLI space. Such collaboration has resulted in some centers developing dedicated multidisciplinary CLI programs and treatment pathways, the positive impacts of which will endure long after the trial comes to completion. In this sense, BEST-CLI has been a unique and invigorating trial, one that shall favorably alter the CLI landscape for many years to come.
This article was authored by Beau M. Hawkins, MD, FACC, University of Oklahoma Health Sciences Center, Oklahoma City, OK, and Eric A. Secemsky, MD, MSc, FACC, Beth Israel Deaconess Medical Center (BIDMC), Harvard Medical School and the Smith Center for Outcomes Research in Boston, MA. Hawkins is a member of the BEST-CLI Recruitment and Retention Committee and Secemsky is an investigator. Contact them using @BeauHawkinsMD and @EricSecemskyMD.
- Roger VL, Go AS, Lloyd-Jones DM, et al. Circulation 2012;125:e2-e220.
- Soga Y, Iida O, Takahara M, et al. JACC Cardiovasc Interv 2014;7:1444-9.
- Adam DJ, Beard JD, Cleveland T, et al. Lancet 2005;366:1925-34.
- Armstrong EJ, Chen DC, Westin GG, et al. J Am Heart Assoc 2014;3:e000697.
- Tepe G, Zeller T, Albrecht T, et al. N Engl J Med 2008;358:689-99.
- Iida O, Nakamura M, Yamauchi Y, et al. Circ Cardiovasc Interv 2013;6:68-76.
- Gerhard-Herman MD, Gornik HL, Barrett C, et al. J Am Coll Cardiol 2017;69:e71-e126.
- Conte MS, Bradbury AW, Kolh P, et al. J Vasc Surg 2019;69:3S-125S.e40.
- Menard MT, Farber A, Assmann SF, et al. J Am Heart Assoc 2016;5(7). pii: e003219.
Keywords: ACC Publications, Cardiology Magazine, Peripheral Arterial Disease, Ocimum basilicum, Prevalence, American Heart Association, Risk Factors, Radiology, Interventional, Uncertainty, Cost-Benefit Analysis, Research Personnel, Prospective Studies, Follow-Up Studies, Quality of Life, Cardiovascular Diseases, Angioplasty, Atherectomy, Endovascular Procedures, Angioplasty, Balloon, Amputation, Stents, Thrombectomy, Cholesterol, Pain, Algorithms, Cohort Studies
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A 2-year-old showed signs of puberty after he was exposed to his dad's testosterone gel. He developed pubic hair and his height was off the charts.
A mom was shocked when her 2-year-old son began to show signs of puberty. Doctors explained that he'd been exposed to his father's testosterone gel.
I had the period talk with my dad when I was 11. It wasn't who I expected to teach me about puberty.
As an adult, the author revisited the conversation she had with her father about periods and puberty. She's grateful to have a dad open to talk.
Chemicals found in makeup, toothpaste, and soap could trigger early puberty. Here's why you should care even if you're not pregnant.
Researchers from the University of California, Berkeley have found that girls exposed to certain chemicals in utero may hit puberty earlier in life
Wondering why your friend has no pimples? The answer lies within the different bacteria in their skin.


text:
G1P3 Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a full length recombinant G1P3.
|Calculated MW||12927 Da|
|Other Names||Interferon alpha-inducible protein 6, Interferon-induced protein 6-16, Ifi-6-16, IFI6, G1P3|
|Target/Specificity||G1P3 (AAH11601, 1 a.a. ~ 130 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||G1P3 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This gene was first identified as one of the many genes induced by interferon. The encoded protein may play a critical role in the regulation of apoptosis. A minisatellite that consists of 26 repeats of a 12 nucleotide repeating element resembling the mammalian splice donor consensus sequence begins near the end of the second exon. Alternatively spliced transcript variants that encode different isoforms by using the two downstream repeat units as splice donor sites have been described.
Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility hot-spot. Johnatty SE, et al. PLoS Genet, 2010 Jul 8. PMID 20628624.The anti-apoptotic protein G1P3 is overexpressed in psoriasis and regulated by the non-coding RNA, PRINS. Szegedi K, et al. Exp Dermatol, 2010 Mar. PMID 20377629.New genetic associations detected in a host response study to hepatitis B vaccine. Davila S, et al. Genes Immun, 2010 Apr. PMID 20237496.Inhibition of G1P3 expression found in the differential display study on respiratory syncytial virus infection. Zhao D, et al. Virol J, 2008 Oct 6. PMID 18838000.Toward a confocal subcellular atlas of the human proteome. Barbe L, et al. Mol Cell Proteomics, 2008 Mar. PMID 18029348.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.

domain: literature


I am having problems with my stock exhaust. The bracket that holds the two pipes together keeps coming apart. This weekend, at Gorman, the guys helped me repair it. Bit of a chore because the 4 seater cage has to come off, but we got it done. Added new gasket (the new one I put in a few months back was gone), rebolted everything back down with additional bolts and nuts, and put her back together. Everything seemed to hold fine. Sound was back to normal, and no rattle was heard. Only problem, I still get backfire on hard decelleration (sp?). Any ideas?


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TPP a Trojan horse
Finally, an article depicting the true face of the Trans-Pacific Partnership (TPP) has appeared in a Taiwanese newspaper.
For at least a year, I have been reading exhortations from Taiwanese media outlets and politicians that the nation must join the TPP, with no reports of the truth about the proposed deal. So the inclusion in the Taipei Times of Joseph Stiglitz’s article on the TPP (“The Trans-Pacific Partnership: the secret corporate takeover,” May 18, page 9) — from an economist who knows just what this Trojan-horse agreement entails — offers a much-needed service for Taiwan and Taiwanese.
For those too busy or disinterested to read the full article, the following excerpt is enough to provide all the information one needs to see through this corporate deception:
“The real intent of these provisions is to impede health, environmental, safety and, yes, even financial regulations meant to protect the US economy and citizens. Companies can sue governments for full compensation for any reduction in their future expected profits resulting from regulatory changes.”
Thank you Taipei Times for finally providing Taiwanese what they need to know about the Trans-Pacific Partnership.
Compost key to future
Kengchi Goah (吳耿志) is perfectly right in his evaluation of Taiwan Semiconductor Manufacturing Co (TSMC) and of higher education in Taiwan (“Shifting to value food production,” May 19, page 8).
I brought computer technology to Taiwan with Hewlett-Packard in 1969 and studied physics at National Taiwan University. My son works at TSMC.
The Japanese saw the potential of Taiwan and wanted to turn it into the breadbasket of Japan. We should go back to this view and make the agricultural field the economy’s main driver.
However, using TSMC-style manufacturing for agriculture as Goah suggests is misguided. We are slowly waking up to the impact of factory farms raising cows, pigs and chickens. Human health pays the price. The same goes for fruit and vegetables. Their health and nutritional content depend on the sun and the natural contribution of good clay soils full of nutrients, most of them unknown to those with doctorates. No LED or chemical fertilizers can get close.
There is a much easier way to bring about an agricultural revolution. Taiwanese produce more than 16,000 tonnes of table scraps a day, most of it burned by huge incinerators producing serious pollution. By composting all of it — which is easy if given the political will — the way I do on my farm at a rate of 2 tonnes a day, we would produce enough of the most nutrient-rich, natural compost to fertilize 10,000 hectares of farmland a year.
Fifty-six percent of farmers in Taiwan try to survive on a monthly income of NT$20,000 per family on small farms totaling 22 percent of all farmland. Meanwhile, the younger generation leaves for the cities and farming is abandoned. This is a major headache for the Ministry of Agriculture.
Take all the potential compost generated by food waste and give it to these small farmers, and their income will jump to NT$200,000 a month, 10 times their actual income. The younger generation will be drawn to the countryside, where the economy lies, and within 60 years, the whole of Taiwan will have an agriculture free of chemical fertilizers and pesticide, as well as a healthy population.
With its passing of Hong Kong’s new National Security Law, the People’s Republic of China (PRC) continues to tighten its noose on Hong Kong. Gone is the broken 1997 promise that Hong Kong would have free, democratic elections by 2017. Gone also is any semblance that the Chinese Communist Party (CCP) plays the long game. All the CCP had to do was hold the fort until 2047, when the “one country, two systems” framework would end and Hong Kong would rejoin the “motherland.” It would be a “demonstration-free” event. Instead, with the seemingly benevolent velvet glove off, the CCP has revealed its true iron
At the end of last month, Paraguayan Ambassador to Taiwan Marcial Bobadilla Guillen told a group of Chinese Nationalist Party (KMT) legislators that his president had decided to maintain diplomatic ties with Taiwan, despite pressure from the Chinese government and local businesses who would like to see a switch to Beijing. This followed the Paraguayan Senate earlier this year voting against a proposal to establish ties with China in exchange for medical supplies. This constituted a double rebuke of the Chinese Communist Party’s (CCP) diplomatic agenda in a six-month span from Taiwan’s only diplomatic ally in South America. Last year, Tuvalu rejected an
US President Donald Trump’s administration on Friday last week announced it would impose sanctions on the Xinjiang Production and Construction Corps, a vast paramilitary organization that is directly controlled by the Chinese Communist Party (CCP) and has been linked to human rights violations against Uighurs and other ethnic minorities in Xinjiang. The sanctions follow US travel bans against other Xinjiang officials and the passage of the US Hong Kong Autonomy Act, which authorizes targeted sanctions against mainland Chinese and Hong Kong officials, in response to Beijing’s imposition of national security legislation on the territory. The sanctions against the corps would be implemented
US President Donald Trump on Thursday issued executive orders barring Americans from conducting business with WeChat owner Tencent Holdings and ByteDance, the Beijing-based owner of popular video-sharing app TikTok. The orders are to take effect 45 days after they were signed, which is Sept. 20. The orders accuse WeChat of helping the Chinese Communist Party (CCP) review and remove content that it considers to be politically sensitive, and of using fabricated news to benefit itself. The White House has accused TikTok of collecting users’ information, location data and browsing histories, which could be used by the Chinese government, and pose

domain: news


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LITTLETON - At least 201 horses currently have Vesicular Stomatitis in Colorado. It's an infectious viral disease that creates sores in horses.
Lesions are often found in the mouth, tongue and coronary band. Dr. Barbara Page at the Colorado Equine Clinic has seen several cases and is alarmed by what she says is a 300% jump in cases over the last week.
"It would kind of be like herpes, people that have herpes sores on their lips. It's a painful situation. They'll salivate, they'll have their heads down, they won't want to eat," said Page.
Vesicular Stomatitis looks identical to the deadly foot and mouth disease that led to 270,000 cattle being euthanized in the United Kingdom in 2007. Foot and mouth was eradicated in the United States in the 1920's but Dr. Page says the state veterinarian still has to be called in to rule out anything more serious.
"Worst case scenario would be if we did not confirm what the virus is and confirm that this is Vesicular Stomatitis and not foot and mouth and the foot and mouth virus got into this country and we didn't know about it and we'd have lots of loss of cattle," Page said.
Horses actually cannot get foot and mouth disease but stopping the spread to cattle prevents panic. Vesicular Stomatitis is spread by direct contact with a lesion or more commonly by flies.
"Keep your windows closed. Keep your doors closed. Don't take the flies inside your vehicle from that area and take them to the next barn," warned Page.
If you do notice any of the signs, either lesions or excessive drooling, contact a veterinarian immediately. Continued spread could impact cattle imports if restrictions are put in place.
Currently an animal with Vesicular Stomatitis is quarantined for 21 days to heal. There is no vaccine for the virus. Currently 133 premises on the state have quarantined horses.
Humans can contract the virus although it is rare. Be sure to wash your hands after handling any animal.
(KUSA-TV © 2014 Multimedia Holdings Corporation)

domain: biology


SYDNEY, AUSTRALIA: Britain plans to send a warship to the disputed South China Sea next year to conduct freedom of navigation exercises, Defence Minister Michael Fallon said on Thursday, a move likely to anger Beijing. Britain would increase in presence in the waters after it sent four British fighter planes for
NEW YORK: Amazon founder Jeff Bezos on Thursday became the world’s richest person, as a jump in the share price of the US tech giant enabled him to overtake Microsoft founder Bill Gates, Forbes magazine estimated. The magazine said its real-time tracking of personal fortunes showed Bezos with a net worth
BEIJING: The election of Indian Prime Minister Narendra Modi has fueled the country's nationalist sentiments and pushing it to war with China, state-sponsored daily Global Times said in an analytical piece on Thursday ‘Since Indian troops illegally crossed into the Doklam area, China and India have been locked in a stand-off
By Sara Saoudi Jadida: Every year for seven years, the International Jawhara Festival brings together artists of Arab and Western music to the delight of the festival-goers who today counts by millions Indeed the artistic program of the 7th edition is breathtaking with the stars of the song in all its splinters.
By Sara Saoudi Under the high patronage of His Majesty King Mohammed VI Help God and glorify him, the Millennium City will Severo Organization of the 97 edition of Cherry Festival 6-9 July 2017; a festival classified as an intangible cultural heritage of Humanity since 2012. Sefrou, this paradise at the foot
WASHINGTON: So far, there are no indications that Pakistan is being isolated in the United States, says Congresswoman Sheila Jackson Lee, who heads the Pakistan caucus in the US Congress. Talking to newsmen at an Inter-Faith Iftar-dinner hosted by the Pakistan Embassy, Ms Jackson Lee also said that the Trump administration


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Mayor Brad Hart told The Gazette on Thursday that the city has asked for about 30 Iowa Department of Transportation trucks to come in to pick up the debris and is using more contractors to help out, totaling 80 to 100 trucks on Cedar Rapids streets “as soon as we clear the power lines.”
“A lot of these trees have power lines wrapped around them,” Hart said from inside the Incident Command Center at the Central Fire Station, a temporary space the city has activated to coordinate its response to an emergency. “That’s the priority right now. We have to clear the power lines so it’s safe to pick up the debris, and that’s been the priority.”
He said debris pickup is already happening, but not as quickly as it will happen once power goes back on in more parts of Cedar Rapids.
“We can unleash 80 or 100 trucks picking up debris. That will be remarkable,” Hart said. “Of course people want that done, but you know, I’m sorry, it’s not safe to do it yet.”
Hart and the city have drawn fire after comments he made in a Wednesday KCRG interview that the National Guard’s help may not be needed.
“We have to make that decision,” Hart told KCRG. “It wouldn’t be the National Guard coming in, it would be the resources they provide, but I think now with all the grappling trucks we have and the contractors we have lined up and other vehicles and equipment from the IDOT we may not need that help.”
The remarks angered some residents who have said they hope to see more resources from the city, state or federal level come in soon to help while widespread power outages remain for a third day.
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During a news conference on Thursday, Hart said he was specifically referring in the KCRG interview to the city not needing the National Guard’s help for tree removal, and that the city absolutely will be seeking assistance from the guard to help with other needs.
The city doesn’t have the authority to activate the guard itself. Before the guard can provide help, the city must provide to state officials a list of needed resources, which he and city staff are working on, he told The Gazette earlier Thursday. Charging stations, ice and door-to-door volunteers to check on residents would be helpful resources, he said.
The National Guard could help with debris removal, Hart said, adding that the city doesn’t need the guard’s help for policing. He also said the curfew was not implemented to prevent looting, for example, but to ensure the community stayed safe by keeping off impassable roads at night.
“I will call (Gov. Kim Reynolds) as soon as I have that list and say, ‘We need your help on this, this and this,’” Hart said.
Asked about Iowa 1st District Rep. Abby Finkenauer calling for a presidential disaster declaration for storm-affected Iowa on Twitter, Hart said he understands she has asked the governor to expedite calls for more aid and added that he “will ask her to expedite that, too.”
“It just adds some resources and it gives businesses and homeowners some ability to recover some of the losses,” Hart said.
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02:13PM | Mon, September 21, 2020
06:30AM | Mon, September 21, 2020
06:00AM | Mon, September 21, 2020

domain: politics


On Friday evening the R-MA Middle School Boys' Basketball team played a home game against the County Christian Catamounts. The young Jackets started the game with a 17-0 run and never looked back. At the end of the first half the Jackets had a 19-7 lead. During the third quarter R-MA went on another run and led 33-9 at the end of the period. The final score was R-MA 37 and County Christian 15. Leading the scoring for the Jackets was Michael Sumner with 16 points. Eighth-grader Stanley Richards scored 6 points; six-grader Sidique Thomas-Sually scored 5; eighth-grader Griffin Loper scored 4 points; and Kota Ikemoto, Ian Mounts, and Daggm Mekonnen each added 2. With this win the young Jackets are 2-0 for the season. On Tuesday, December 9, the boys travel to Ressie Jeffries school in Front Royal to play an conference game against Riverfront Christian. Game time is at 5:00. On Thursday, December 11, the R-MA team travels to Berryville, Virginia for a non-conference contest against Powhatan. On Friday, December 12, the Jackets host Fresta Valley in a conference game.


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- Patriot Act author on James Clapper: Fire, prosecute him
- Russia P.M. Medvedev: No amnesty for political prisoners
- Michigan GOP Senate hopeful reminds government is the ‘servant’
- Christmas, by Congress: Members mull a 15-cent tax on trees
- U.S. unemployment falls to five-year low of 7 percent; 203K jobs added
- World mourns Nelson Mandela and celebrates his life; burial set for Dec. 15
- Bill O’Reilly reminds: Nelson Mandela ‘was a communist’
- John Boehner says GOP should support gay candidates: ‘I do’
- Grass-Whopper: Pan-fried cricket burgers go over big in New York City
- CDC sees measles spike and ‘failure to vaccinate’
Lucasfilm rejects bid to restart N. Calif project
SAN RAFAEL, CALIF. (AP) - A company owned by George Lucas on Wednesday rejected a move by Marin County officials to persuade the filmmaker to resurrect a plan to build a massive film studio north of San Francisco.
The Board of Supervisors on Tuesday passed a resolution commending the “Star Wars” creator and calling on him to move forward with the controversial Grady Ranch project.
The panel pledged to help Lucasfilm Ltd. clear regulatory hurdles that could slow down its construction.
“George, I want to thank you for all you have done,” declared Supervisor Judy Arnold, speaking at a camera used for the county’s webcast. “Reconsider! Come back! Let’s finish the Grady Ranch project!”
Board President Steve Kinsey said all the supervisors support the digital production compound that would generate tax revenue and hundreds of jobs. He said it would be approved if it came before the board.
Lucasfilm spokeswoman Lynne Hale told The Associated Press on Wednesday that it was too late for the company to reconsider.
“We truly appreciate all the support but unfortunately it has come too late in the process,” Hale said in an emailed statement. “It was not easy but at the end of the day we have business needs. We waited as long as we could.”
Lucasfilm shocked Marin County last week when it announced it was abandoning the project, citing regulatory delays and fierce opposition from homeowners who fear the sprawling complex will lead to more noise, traffic and environmental problems.
The company said it hopes to sell the Lucas Valley property to a developer interested in building low-income housing. Officials said the company is in talks with two cities offering substantial incentives to build the studio.
Information from: Marin Independent Journal, http://www.marinij.com
- Spike in battlefield deaths linked to restrictive rules of engagement
- Activists urge Obama to go rogue, sidestep Congress
- Bill OReilly reminds: Nelson Mandela was a communist
- PRUDEN: British press horrified as London's new mayor dares to proclaim the truth
- 'Hunger Games' delivers Obama's message on income inequality
- New battlefront emerges in war between Republicans, tea party
- U.S. pilot scares off Iranians with 'Top Gun'-worthy stunt: 'You really ought to go home'
- Obama administration issues permits for wind farms to kill more eagles
- Budget negotiators look to federal workers for benefit concessions
- Obama downplays IRS scandal, blames Obamacare rollout on 'outdated' agencies
Independent voices from the The Washington Times Communities
A politically conservative and morally liberal Hebrew alpha male hunts left-wing viper
This column will cover anything that has anything remotely to do with the game of baseball, from the game itself to mid-summer trades to offseason moves.
Entertainment News and Reviews from Washington, D.C. and beyond.
Political satirist and Christian apologist Bob Siegel discusses religion and politics.
White House pets gone wild!


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27 September 2017 | Press Release
The regional organization’s Executive Secretary, Alicia Bárcena, made a presentation at the IV Regional Conference on Prospects for Triangular Cooperation in Latin America and the Caribbean, held in Lima, Peru.
13 November 2013 | Press Release
During her two-day visit to the European country, Executive Secretary, Alicia Bárcena, described the development challenges of Latin America and the Caribbean.
9 de January de 2012 | Speech
Por Alicia Bárcena, Secretaria Ejecutiva de la CEPAL

domain: geography


Are plants multicellular or unicellular? multicellular Prokaryotic or eukaryotic? Eukaryotic
List the plant divisions (phyla) in order from simple to complex?
Seedless Vascular Plants
Biological Processes & Systems:
If white blood cells attack any of your body cells, what type of disease (category) would that be? Autoimmune disease
Which system is involved with the removal of urea from cells creating urine? Excretory system
List some limiting factors that would affect a plant (such as a corn plant) population. Light, carbon dioxide concentration,
temperature, nutrients in soil, water
List some limiting factors that affect an animal such as a field mouse .


The Internet took a weird turn Thursday when all of a sudden everyone started buzzing about the color of a dress. A woman had taken to Tumblr the day before to ask a seemingly normal question: what color is this dress?
But there was something off about the dress and the image. The woman says when she saw a photo of the dress once, it was blue and black (she even posted a photo of the dress being worn at a wedding. In that image, it appears to be blue and black) but when she looked at it again, the dress was gold and white.
This is about the point where the Internet broke.
Her Tumblr got flooded with comments. “i’ve gained over a thousand followers so all I’m going to say is hello,” the user known as swiked posted Thursday. Twitter erupted. Gawker posted it. BuzzFeed did, too. BuzzFeed even seems to have solved the mystery.
But that still doesn’t quite explain why the image appears white and gold to some and blue and black to others. Probably eye, light, mind tricks, but hopefully scientists of the world are hard at work trying to figure this out. Maybe, just maybe, we’ll get some great think pieces out of it, too.
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- The Most Anticipated Books, Movies, TV, and Music of Fall 2023
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Universal Pictures Canada x Mr. Will are thrilled to give Readers a chance to win Advance Passes to see TICKET TO PARADISE.
Screenings take place as follows on Wednesday, October 19, 2022:
Toronto: Scotiabank Theatre at 7:00 pm
Montreal: Cineplex Forum at 7:00 pm
Vancouver: Scotiabank Theatre at 7:00 pm
Academy Award® winners George Clooney and Julia Roberts reunite on the big screen as exes who find themselves on a shared mission to stop their lovestruck daughter from making the same mistake they once made. From Working Title, Smokehouse Pictures and Red Om Films, Ticket to Paradise is a romantic comedy about the sweet surprise of second chances.
Directed by Ol Parker (Mamma Mia! Here We Go Again, writer of the Best Exotic Marigold Hotel films) from his script with Daniel Pipski, Ticket to Paradise is produced by Tim Bevan (Darkest Hour, The Danish Girl) and Eric Fellner (The Theory of Everything, Les Misérables) for Working Title, by Sarah Harvey (The Best Exotic Marigold Hotel, co-producer In Bruges), by Deborah Balderstone (Palm Beach, Gone), by George Clooney and Oscar® winner Grant Heslov (Argo, The Midnight Sky ) for Smokehouse Pictures and by Julia Roberts and Lisa Roberts Gillan and Marisa Yeres Gill (both co-executive producers, the Homecoming series) for Red Om Films.
To enter for a chance to win, click “like” on this Post atMR. WILL ON FACEBOOK.Re-Tweet the Contest Tweet below for an extra chance!
Enter for a chance to #win Advance Passes to see #TickettoParadise starring Julia Roberts and George Clooney! Tickets available for Toronto, Montreal and Vancouver.

domain: artistic


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London Mayor Sadiq Khan has confirmed that drivers will have to pay to drive through the Blackwall Tunnel from 2025, and that it should come as “no surprise”.
He told the London Evening Standard newspaper it had been in the pipeline for years, and was needed to help pay for the new Silvertown tunnel, which is due to open in two years’ time.
“There’s nothing sudden about it,” Mr Khan told the Standard. “The intention is for both the Silvertown tunnel and the Blackwall tunnel… to be tolled. What we don’t want to see is displacement as a consequence of one being tolled and not the other.
“Also, the [Silvertown] tunnel hasn’t been paid for using taxpayers’ money or the TfL budget. It’s being paid for by borrowing against future receipts coming in through the tunnels.”
Some reports suggest car drivers will have to pay £4 to use the tunnels, because draft signage submitted for approval had that price on it. However Transport for London say the levy is yet to be set, and that the prices on the draft signs were placeholders.
(Picture – TfL)

domain: finance


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State Rep. Rudy Veit is frustrated with the Missouri Department of Revenue, and he’s not the only one.
Legislators have a right to be frustrated. They’ve been given varying pictures of the state’s revenue. A month ago, they were told revenue was down $250 million. Now, they’re being told the shortfall is up to $350 million.
For lawmakers to do their job of finalizing the state’s budget for the fiscal year that begins July 1, they need accurate numbers.
The revenue shortfall is blamed on the 2017 federal income tax reduction, which affects Missouri.
First the Revenue department said they made an error in withholding that would cause many people to owe the state more in their state income tax. Then, Revenue officials said they didn’t make a withholding error.
The confusing mixed signals and criticism of the department have led to the resignation of the department’s director, Joel Walters.
Walters resigned a day after the Columbia Daily Tribune reported the department drafted a press release late last year advising taxpayers to increase their withholdings from paychecks. The idea was to give advance warning that they might owe more, so they should withhold more. The only problem is the news release never was disseminated.
So, just as lawmakers have a right to be frustrated, so do taxpayers.
Gov. Parson has complained that lawmakers have been “grandstanding” on Revenue’s tax blunders.
But lawmakers have a right to grouse — the issue not only makes the department look incompetent, it affects the lives of Missourians.
Walters’ departure may signal the state takes the issue seriously, but the Missouri Department of Revenue still owes Missourians a better and more thorough explanation than they’ve been given.


Mattias Janmark scored his first career hat trick to lead the Vegas Golden Knights to a 6-2 victory over the Minnesota Wild in Game 7 of the first round of the West Division playoffs in Las Vegas.
Marc-Andre Fleury made 19 saves for the Knights, who move on to face No. 1 seed Colorado in the second round on Sunday night in Denver.
tap here to see other videos from our team.
Max Pacioretty scored the go-ahead goal during a three-goal second period. Nicolas Hague and Zach Whitecloud also scored goals, and Chandler Stephenson and Shea Theodore each had two assists for Vegas.
Janmark, obtained from Chicago in a three-way trade with San Jose on April 12, had scored just one goal for the Golden Knights entering the contest.
Zach Parise and Kirill Kaprizov scored goals and Cam Talbot finished with 29 saves for Minnesota, which had staved off elimination twice while battling back from a 3-1 series deficit.
Vegas took a 1-0 lead at the 5:09 mark of the first period when Janmark broke in between a pair of Wild defenders, deked Talbot and then slid a shot past the right pad of the Wild goalie.
Parise, a healthy scratch in the first three games of the series, then tied it late in the period with his second goal of the playoffs, posting up in front of the crease and then backhanding a shot between his legs and Fleury’s pads.
Shortly after Kaprizov fired a shot off the crossbar, the Golden Knights took a 2-1 lead early in the second period when Hague fired a wrist shot through traffic from the left point for his first playoff goal.
Minnesota tied it with a power-play goal by Kaprizov, who took a pass from Mats Zuccarello while cutting in front of the right circle and buried a shot through Fleury’s pads for his second goal of the playoffs.
Pacioretty, left alone in the slot, then gave Vegas a 3-2 lead midway through the period when he one-timed Stephenson’s pass from along the left boards. It was the first goal since April 28 for Pacioretty, who was making his playoff debut after leaving a May 1 game at Arizona with an undisclosed injury.
Whitecloud made it 4-2 later in the period with his first playoff goal, beating Talbot with a wrist shot from the centre of the right circle. Janmark then sealed with his second goal of the game off a feed from Nicolas Roy with 7:24 left.
Minnesota pulled Talbot with 4:58 to go and Janmark completed the hat trick with an empty net goal.


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River Falls firefights deal with night fire
A town of River Falls shed near a two-car garage caught fire Tuesday night, Oct. 22, just before 10 p.m.
Prescott’s fire department was called for mutual aid to provide extra water. That call was soon canceled.
Fire Chief Scott Nelson said the blaze appeared to have started around an outdoor wood boiler.


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Houses of Worship
This directory of Houses of Worship service providers was compiled by Sandhills PRIDE to provide the Moore County LGBTQ+ community with a listing of local professionals who are accepting of the LGBTQ+ community and welcome its business.
Congregational Church of Pinehurst, UCC
895 Linden Road
The Congregational Church of Pinehurst (CCP) mission is to follow Jesus’ way of love, justice and inclusion by recognizing and celebrating the diversity of God’s people. We are an ONA congregation that we interpret as Open to all; and Affirming of All. As such we have a partnership with Sandhills Pride. Wherever you are on your spiritual journey today, you will be welcomed at CCP. CCP is located across from Elliott’s Restaurant. We worship every Sunday at 10:00am and you are welcome to check us out. You can learn more about our church by visiting our website: www.congregationalchurchpinehurst.org
Emmanuel Episcopal Church
350 E. Massachusetts Ave.
Southern Pines, NC
The clergy and leadership at Emmanuel Episcopal have been very supportive of Sandhils Pride and our mission. For the past two years, we have held our Thanksgiving potluck at Emmanuel Episcopal, and have been welcomed warmly. Many supporters of Sandhills Pride are church members.
Unitarian Universalist Congregation of the Sandhills
1320 Rays Bridge Rd.
Whispering Pines, NC 28327
The core of Unitarian Universalism is the freedom of belief along with the responsibility to seek truth and meaning. There is no set creed and there are no required beliefs. We are united by our freedom to question, our agreement that it is all right to be in doubt, and that the search for individual truth may be aided by common effort. We invite all who share our vision to join us in this spiritual journey.
We are a welcoming congregation who envision a life filled with compassion for all, where the LGBTQ+ community is able to experience the inherent worth and dignity of every person.
131 Jackson Springs Rd.
Jackson Springs, NC 27281
The Sandhills Jewish Congregation at Temple Beth Shalom is the only Jewish congregation within an hour drive. While the temple belongs to the Union for Reform Judaism, its members include Jewish families of all denominations. The congregation welcomes the LGBT community, and is served by Rabbi Kenneth Brickman, who, with his husband, divides his time between Pinehurst and NYC.

domain: sociology


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Tomato Black Krim (Organic)
This is heirloom-type tomato has flattened, dark red-purple fruit with green shoulders. Flesh is very juicy, with a green tinge. Plants must be staked. Yates organic seeds have been grown just as nature intended, under strictly controlled, organic, chemical free conditions.
- Organically grown
- Heritage variety
- Rich flavour
Sow direct in warm conditions or raise in trays of Yates Seed Raising Mix. Firm down and keep moist. Transplant when 5cm high.
Choose a well drained sunny position. Prepare soil by adding Yates Blood & Bone or Dynamic Lifter Organic Plant Food. Apply Yates Uplift Organic Plant Food or another organic liquid fortnightly for a good yield.
Protect from pests and diseases with regular applications of Yates Tomato and Vegetable Dust. In fruit fly-affected areas use Nature's Way Fruit Fly Control.
Great companion plant for basil, broccoli, carrots, celery, onions, marigolds, marjoram, parsley & parsnip. Fruit contains health promoting lycopene.

domain: agronomy


Portland Timbers select Dawson McCartney in MLS SuperDraft
On Jan. 21, Dawson McCartney, former Dartmouth midfielder and member of the Class of 2021, was selected 43rd overall in the Major League Soccer SuperDraft by the Portland Timbers, becoming the fifth player from Dartmouth drafted to play in MLS in the past four years.
McCartney spent three seasons at Dartmouth before transferring to the University of Notre Dame in December. During his time at Dartmouth, McCartney was named Ivy League Rookie of the Year in 2017 after finishing the season with two goals and a team-high eight assists while helping lead the Big Green to an Ivy League title with a 6-0-1 record in conference play. He followed up his stellar freshman campaign with six goals and six assists over the next two seasons, earning Second Team All-Ivy honors each year.
McCartney said making it into MLS has been a lifelong goal.
“It’s been one of my dreams ever since I can remember,” McCartney said. “It was an amazing feeling.”
Teammate Tiger Graham ’21 said he was “really excited” to hear McCartney had been drafted into MLS.
“I think it’s a big achievement for him,” Graham said. “I know playing professionally was his big goal, so I’m glad to see he was able to make it happen.”
McCartney looks back fondly on his time at Dartmouth, particularly appreciating his teammates and their impact on his Dartmouth experience.
“I loved all my years at Dartmouth,” McCartney said. “[I] couldn’t have asked for a better three years. I had an amazing group of guys. … Just an amazing experience.”
Before arriving at Dartmouth, McCartney played soccer at YSC Academy, a high school that combines academics with a rigorous soccer program run by the Philadelphia Union Academy, an MLS team development program. McCartney worked his way through the Union Academy onto Bethlehem Steel FC, a United Soccer League affiliate team, and made his professional debut during his senior year of high school.
Graham, who played with McCartney in high school and at Dartmouth, emphasized McCartney’s desire to win as a quality that always stood out.
“Every day in training, he was the hardest working player,” Graham said. “He hates losing. It doesn’t matter how small of a drill [or] game it is. ... [McCartney] will do whatever it takes to be the winner at the end of the game.”
Dartmouth head coach Bo Oshoniyi echoed Graham’s sentiments.
“Every training session, every match that we played, he always walked off as the best player on the field,” Oshoniyi said. “That was because of his intensity, his willingness to work hard [and] his willingness to pick up teammates as well — he was just phenomenal with that.”
The pandemic-delayed season threw a wrench in what would likely have been a typical ascent to MLS for McCartney. His reporting date is unclear, but he hopes to begin playing in Portland soon.
While McCartney was the only Ivy League player drafted this year, he joins four other former Big Green players drafted in recent years: Matt Danilack ’18, Justin Donawa ’19, Eduvie Ikoba ’19 and Wyatt Omsberg ’18.
For now, McCartney plans to focus on earning a spot on the Timbers roster.
“My immediate goal is to earn a contract,” McCartney said. “Obviously nothing is handed to me. I have an opportunity to go out there and prove myself and earn a spot on the roster. … From there, [I want to] try to be as much of an impact player as I possibly can over the year.”


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This volume brings together philosophical perspectives on emotions, imagination and moral reasoning with contributions from neuroscience, cognitive science, social psychology, personality theory, developmental psychology, and abnormal psychology. The book explores what we can learn...
Published November 23rd 2011 by Psychology Press
The essays collected in this volume address a range of issues that arise when the focus of philosophical reflection on identity is shifted from metaphysical to practical and evaluative concerns. They also explore the usefulness of the notion of narrative for articulating and responding to these...
Published June 7th 2010 by Routledge

domain: library


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And it wouldn't be outrageous to add crushed potato chips
If frosting were a game changer, this would be it
Bye for now!
A recipe found, tested, and adored just in the nick of time
Spoiler: 12 pounds of butter.
It won't be scared by ill-equipped kitchens
We ate so many vegetables
Start the kettle.
Okay, okay, it's zucchini! (And sweet potatoes!)
Good enough to bribe Zao Jun, good enough for us
Chicory, chocolate, and mayonnaise—who knew?
Leave it to Sqirl's Jessica Koslow
Gather 'round (there's cake)
A cake with roots.
A simple sponge cake that's stood the test of time.
I ain't no hasselback potato.
A goodie-rich Italian cake.
Island style, but all frosting and chocolate.
Are your cake pans out and your costumes on?
Happy as a hummingbird (cake)
In two layers: one yeasty, one melty
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domain: food


All fields are required.
The U.S. Department of Transportation (USDOT) is seeking comments on policies, guidance documents and regulations that may create obstacles to transportation infrastructure projects.The USDOT is reviewing existing polices, guidance and regulations that may be unnecessary. As part of its review, it's asking affected stakeholders and the public to help identify non-statutory requirements that should be removed or revised, according to a notice posted last week on the Federal Register. Comments should be received no later than July 24. Instructions for filing comments can be found via this link.
Amtrak should pay for Penn Station disruptions, Cuomo says »
Trudeau pledges funding to build light rail in Montreal »
FRA, MDOT issue 'no impact' finding for Susquehanna rail bridge project »
MBTA to study future commuter-rail needs »
UP maps infrastructure projects in Minnesota »


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A concert organized by a men's rights group on the Toronto Islands this weekend has been cancelled by the venue's manager, which felt that the event would become too political.
The Canadian Association for Equality planned the festival at Artscape Gibraltar Point to mark what it was calling E-Day, a day to promote men's parental rights in partnership and marriage breakdowns. Specifically, the day was supposed to support Bill C-560, which calls for an amendment to Canada's Divorce Act that would instruct judges to apply shared parenting unless there is proven neglect or abuse.
Artscape, a creative non-profit organization, cancelled the event after a flurry of e-mails and Facebook posts indicated that attendees might get political, which goes against the organization's policy, said its communications director, Liz Kohn.
"The premise of the event as it was given to us was a fair and equitable event that was family-friendly and a lovely music festival," she said. "It has since turned political and we anticipated that there could be health and safety concerns as well."
Gene Hughes, E-Day founder and a CAFE board member, originally said he was not concerned that the concert was scheduled only a week after Elliot Rodger's murderous rampage in California last week, which sparked the #yesallwomen and #notallmen hashtags and a global online conversation about violence against women.
The concert had been in the works since January, he said, and had nothing to do with the University of California, Santa Barbara, killings.
"It's more about the party," he said.
Since the cancellation, however, Mr. Hughes said he is disappointed that Artscape could not see through a few fringe voices. "They backed off because they are afraid of a little controversy. This is an artistic organization, they're supposed to stand up for what's right, they should be aware of the potential controversy," he said.
CAFE has sparked protests in the past surrounding its attempts to open several university chapters. The most recent controversy was at Ryerson University last fall when it formed a branch without the support of the school's student union.
Notable artists that were in E-Day festival lineup included Ron Hawkins (formerly of Lowest of the Low) and the Do Good Assassins and Spookey Ruben.
The Toronto Islands have been the site of concerts in the past, including Electric Island and the Toronto Island Concert series.
Mr. Hughes said he has no immediate plans to reschedule the E-Day event.


Children and Family Relationships Act 2015
DAHR facility to retain and provide certain information
28. (1) An operator of a donation facility shall retain—
(a) a written consent of a person made under section 6 , and
(b) a record of the revocation, under section 8 , by a person referred to in paragraph (a) of his or her consent.
(2) An operator of a DAHR facility shall retain—
(3) Where a DAHR procedure is performed at a DAHR facility, the operator of the facility shall retain a record of—
(a) all information acquired under section 24 in respect of the donor concerned, and
(b) all information obtained under section 25(3)(a) in respect of the intending parent concerned.
(4) The operator of a DAHR facility referred to in subsection (3) shall provide the Minister, for the purpose of the performance by the Minister of his or her functions under section 33 , with the following information:
(a) that a DAHR procedure has been performed at the DAHR facility at the request of the intending parents;
(b) the information referred to in subsection (3) in respect of the donor and the intending parent;
(c) where known to the operator—
(i) whether the procedure has led to the pregnancy of the intending mother, and
(ii) where the procedure has resulted in the pregnancy of the intending mother, the date on which the intending mother is expected to give birth or, where applicable, the information specified in subsection (5) .
(5) Where the pregnancy of the intending mother referred to in subsection (4)(c)(i) has come to an end, the information to be provided under that subsection is the following:
(a) whether the pregnancy resulted in the birth of a live child;
(b) where the pregnancy resulted in the birth of a live child, the name, date and place of birth, sex and address of the child.
(6) Subject to subsection (7), the information referred to in subsection (4) shall be provided to the Minister, in relation to each DAHR procedure performed at the DAHR facility, on each of the following dates—
(a) on a date that is no later than 6 months after the performance of the procedure concerned, and
(b) on a date that is no earlier than 12 months and no later than 13 months after the performance of the procedure concerned.
(7) Where the operator of a DAHR facility becomes aware of an error in information provided by it under subsection (4), he or she shall without delay inform the Minister of the error and provide the Minister with corrected information.


It is frequently reported that, in order to leave the Knicks and sign elsewhere—with the Lakers or the Bulls, for example—Knicks star Carmelo Anthony would have to leave about $30 million on the table. The number, though, is more like $33 million and, what’s more, even that is not quite right.
Under NBA rules, no matter where Anthony signs, he is able to start his next contract at 105 percent of his previous year’s salary. He will have made $21.39 million this year, which means his salary next year will be $22.46 million.
Things diverge after that. If Anthony signs with the Knicks, he can sign using his Bird rights, a loophole in the CBA that allows an exception to the salary cap for teams signing their own players. The maximum contract for a player signing using Bird rights is five years, with raises of 7.5 percent.
If Anthony signs elsewhere, he can only do so for a maximum of four years, with 4.5 percent raises.
Thus, Anthony’s max contract with the Knicks would go:
2014-’15: $22.46 million
2015-’16: $24.14 million
2016-’17: $25.83 million
2017-’18: $27.51 million
2018-’19: $29.20 million
Total: $129.1 million
But Anthony’s contract with another team, at four years and with 4.5 percent raises, would go:
2014-’15: $22.46 million
2015-’16: $23.47 million
2016-’17: $24.48 million
2017-’18: $25.49 million
Total: $95.9 million
The difference between the two contracts, then, is $33.2 million.
That, however, discounts the ’18-’19 season altogether. While there is no guarantee that Anthony will play that year—he could suffer an injury or retire—he will only be 34, and given the way players like Dirk Nowitzki, Tim Duncan and Kevin Garnett have performed well into their 30s, it is hard to imagine he won’t be able to sign a sign a short-term deal that pays him at least in the $18-20 million range at that age.
If he leaves the Knicks for the smaller contract, but wins a championship in a place like Chicago or L.A., that could boost his value even more at age 34. He could still be a $22-24 million-per-year player then. Or more.
But even if he does slide some, on the conservative side, it would be safe to assume that Anthony would make at least $18 million for the ’18-’19 season. The trio of Nowitzki, Duncan and Garnett made an average of $19.5 million at age 34, and those contracts were under a smaller salary cap. Duncan also took a voluntary salary cut.
Supposing that Anthony does make $18 million in ’18-’19—it would be inaccurate to say he had left $33.2 million on the table. It would be $15.2 million. That is a significant amount, obviously, but shows that the financial gap between Anthony staying in New York or going elsewhere isn’t necessarily as great as has been reported.


Pearl Motor Yachts will be exhibiting its latest model, the Pearl 50, for the very first time at this year’s show. The ultimate luxury flybridge cruiser will be making its debut on stand P11/P12 alongside the stunning flagship Pearl 60.
The Pearl range has become renowned for it spacious layout offering more accommodation than any of its competitors. The remarkable combination of a full-length flybridge and multi-stateroom design positions the master and VIP staterooms at opposite ends of the yacht, affording all guests maximum privacy whilst onboard.
Owners of the Pearl 50 have the choice of a dining area opposite the galley or a third full size twin cabin complete with en-suite, whilst Pearl 60 owners have the option of specifying a crew cabin to produce a possible five cabin layout. In addition the Pearl 60 offers open plan or separated saloon/galley options.
Real wood finishes, sprung mattresses and external open-cell foam upholstery are just a handful of features included in the hundreds of thousands of pounds worth of intelligent features fitted as standard on each yacht.
Powered by twin Volvo engines ranging from 500-575hp, the Pearl 50 has a comfortable cruising speed of 26 knots and a top speed of 32 knots. The Pearl 60 is equipped with twin Volvo D12 775hp engines offering similar performance.
Externally, Pearl’s commitment to intelligent design is also evident, from the hydraulically operated bathing platform and aft deck sunroof system to the electrically operated patio door and concealed hydraulic passarelle.
As one of the first boat builders in the UK to move to vacuum infusion to produce its hulls, Pearl’s yachts are also significantly kinder to the environment as, unlike traditional manufacturing techniques, the process does not produce styrene fumes. It also ensures even lamination, making the boat stronger and requiring less resin than a traditional lay-up, resulting in a lighter, faster and more fuel-efficient boat.
Length: 49 ft. & 3 in.
Beam: 14 ft. & 6 in.
Draft: 4 ft. & 7 in.
Fuel capacity: 440 gal
Water capacity: 110 gal
Engines: 2xVolvo D9 500hp
Max Speed: 30 Knots
Cruising Speed: 24 Knots


By; TINA PHINEAS, Yola
As the world celebrated the International Women’s Day (IWD), the first lady, Federal Republic of Nigeria, Aisha Bihari, has called for an end to the trend of kidnapping and abduction of women and girls in the country.
A statement signed by the first lady and made available to New NIgerian stated that the IWD offers opportunity for humanity to review and reflect on progress made on issues of women and girls.
She maintained that this year’s theme: Women In Leadership: Achieving on Equal Future in a COVID-19 World is a call to appreciate the efforts of women and girls in the fight against the COVID-19 pandemic.
“COVID-19 has had a huge impact on women; disrupted education and careers lost jobs, descend into poverty, and proliferation of domestic violence.
” Many have also died or suffered due to lack of access to basic information on the pandemic, It is therefore important, not just to continue spreading the message of the COVID-19 protocol, but to remember and support those who have been affected negatively by the pandemic in one way or another”, Mrs Bihari stated.
The first lady pointed that part from COVID-19, women and girls in Nigeria have continued to suffer abductions both in the hands of insurgents and bandits.
“As a mother, I share the sorrow and agony of the victims and their families. I am also not unaware of the impact that these abductions could have in reverting many successes we have hitherto achieved, especially in terms of girl-child education and early marriages”, she stated.
While commending women all over the world for their resilience, hard work, and commitment to the progress of humanity, the first lady urged all stakeholders to continue to exert their different levels of influence and bring these abductions to an end and to assure us that girls are safe anywhere they may find themselves.


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SUNDERLAND’S low carbon Enterprise Zone could be set for a share of £100million Government cash.
Communities Secretary Eric Pickles announced today Whitehall is inviting Local Enterprise Partnerships (LEPs) to bid for money to fund key infrastructure projects such as road building and land clearance to create thousands of jobs.
The LEPs have already supported 180 businesses, welcomed half a billion pounds of private sector money and generated almost 4,000 jobs.
Paul Woolston, chairman of the North East Local Enterprise Partnership, one of the largest in the country, said: “It’s great news that £100million of government funding for Enterprise Zone infrastructure works is being made available.
“The North East Enterprise Zone offers once-in-a-lifetime opportunities to the region.
“It was the first in the country to have a major development underway, and it has attracted companies and developers in automotive, offshore and energy-related sectors.”
The North East Enterprise zone covers sites along the A19 designed to attract businesses working in the low carbon sector and has attracted Vantec Europe’s completed development and the Washington Business Centre, which is now under construction, as well as redevelopment of a site on the north bank of the Tyne as part of a manufacturing scheme and a development of the Port of Blyth site. “The North East LEP area has the infrastructure, the skilled workforce and a strong supply chain in sectors such as the offshore, energy and automotive industries.
“Our North East Investment Fund has already loaned £10million to projects in the Enterprise Zone, and can help many more companies invest.
“All this means the added value of locating at the North East Enterprise Zone sites gives its occupiers a competitive edge in a global market.”
Sunderland City Council leader Councillor Paul Watson added: “We have identified the remaining infrastructure required for the Sunderland Enterprise Zone, and there’s already strong interest from businesses prepared to invest and create jobs once this infrastructure is in place.
“With the Vantec investment and the new Washington Business Centre, the Sunderland Enterprise Zone is already the most successful in the country.
“We’ve got a strong track record for attracting inward investment in Sunderland and we’re all looking forward to more progress, more investment and more job creation here.”


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View Full Version : Edited Database on a Network Game
Is it possible to play a Network game with an edited database?
Or does it cause problems?
Will it make any difference if all players have the edit on their computer?
Should be fine.
The client gets the data from the host's database, so it won't make a difference what the other players have or don't have. They'll be able to see you've made changes on the status screen though, so if you're doing it to cheat then i'd watch out ;)
Thanks. No not to cheat at all just wanted to download an update for summer transfers
anyone playing online with an edited database has to have the same edited file or te game wont run right
Ok so those are conflicting answers. Anyone have any experience of using an edited database online?
I've only ever played Network games with my mate, and we've edited a few things ourselves with me only ever being the host, with the edited file... and never run into one single problem... stretch this over the last 9 or so years?
Powered by vBulletin® Version 4.1.4 Copyright © 2014 vBulletin Solutions, Inc. All rights reserved.

domain: hobby


text:
The Brothers at OTAA stand for impeccable design, and this Flax Linum Blue Floral Pocket Square is a magnificent example. Beautifully finessed with an intricate floral pattern, this Flax Linum Blue Floral Handkerchief was designed to incite your ensembles with sophistication. This Flax Linum Blue Floral Handkerchief features an elegant floral pattern with a cool-toned palette. Designed exclusively by the Brothers at OTAA, this magnificent flower pattern is complemented by green and pink features with light, medium and dark blue shades. The indulgent black background of this pocket square means it’s a versatile staple that can be worn with a myriad of formal ensembles.
Pocket Square Code : C539-PS
Colour : Black, Blue, Pink, Green
Pocket Square Style : Floral Design


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One question we get here at ushuru.co.ke is what penalties apply to taxpayers in Kenya, whenever there is a failure to pay tax or file a tax return.
The most common penalty is a single penalty of KES 20,000 per year for failure to file an individual tax return. Every individual is required to file a tax return by the 30 June of every year. Such a return shows what tax has been paid by the individual on employment income, agricultural income and business income.
This penalty of KES 20,000 is a single and flat penalty, meaning that even where it applies and is not paid immediately, the penalty does not increase. What is also important to note is that the iTax system allows for tax returns to be filed only from 2013. Any year before 2013, a tax return cannot be filed online.
This also means that, depending on when your PIN was registered, if you have never filed a tax return since 2013, you would be required to pay a total penalty of KES 80,000 (for the four years when a tax return was not filed).
Even where an individual did not make any money during a tax year, a tax return is still required to filed by an individual.
The reason why the penalty of KES 20,000 is applicable is because, often times, all the tax has been paid by the filing date. If at the time of the filing date there is still tax outstanding, then the penalty applicable is 20% of the tax outstanding in addition to interest at a rate of 1% per month.
So if you haven’t filed your tax returns, the applicable penalties should not stop you from doing so as making an effort to keep and remain tax compliance is what matters most. Approach us to file your tax returns for you and let’s get you on your way to a clean tax slate.


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Consumption patterns of sweet drinks in a population of Australian children and adolescents (2003–2008)
1 Research Unit for Dietary Studies, Institute of Preventive Medicine, Copenhagen Capital Region, Copenhagen University Hospital, Frederiksberg, Denmark
2 Centre for Research in Childhood Health, Institute of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark
3 Centre for Intervention Research in Health Promotion and Disease Prevention (previous: Centre for Applied Research in Health Promotion and Prevention), The National Institute of Public Health, University of Southern Denmark, Copenhagen K, Denmark
4 WHO Collaborating Centre for Obesity Prevention, Deakin University, Geelong, Australia
5 Department of Public Health, University of Oxford, Oxford, United Kingdom
6 Melbourne School of Population Health, University of Melbourne, Melbourne, Australia
7 School of Psychology, Deakin University, Geelong, Australia
BMC Public Health 2012, 12:771 doi:10.1186/1471-2458-12-771Published: 12 September 2012
Intake of sweet drinks has previously been associated with the development of overweight and obesity among children and adolescents. The present study aimed to assess the consumption pattern of sweet drinks in a population of children and adolescents in Victoria, Australia.
Data on 1,604 children and adolescents (4–18 years) from the comparison groups of two quasi-experimental intervention studies from Victoria, Australia were analysed. Sweet drink consumption (soft drink and fruit juice/cordial) was assessed as one day’s intake and typical intake over the last week or month at two time points between 2003 and 2008 (mean time between measurement: 2.2 years).
Assessed using dietary recalls, more than 70% of the children and adolescents consumed sweet drinks, with no difference between age groups (p = 0.28). The median intake among consumers was 500 ml and almost a third consumed more than 750 ml per day. More children and adolescents consumed fruit juice/cordial (69%) than soft drink (33%) (p < 0.0001) and in larger volumes (median intake fruit juice/cordial: 500 ml and soft drink: 375 ml). Secular changes in sweet drink consumption were observed with a lower proportion of children and adolescents consuming sweet drinks at time 2 compared to time 1 (significant for age group 8 to <10 years, p = 0.001).
The proportion of Australian children and adolescents from the state of Victoria consuming sweet drinks has been stable or decreasing, although a high proportion of this sample consumed sweet drinks, especially fruit juice/cordial at both time points.

domain: medical


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Federal Enterprise Architecture Program Management Office April 2003 Draft Performance Reference Model: Overview for Federal Agencies
The President has clearly challenged OMB and agencies to improve performance for citizens.
Meeting this challenge will require OMB and agencies to improve performance while reducing costs
“ This Administration’s goal is to champion citizen-centered electronic government that will result in a major improvement in the federal government’s value to the citizen.” ~ The President’s Management Agenda “ Our success depends on agencies working as a team across traditional boundaries to serve the American people, focusing on citizens rather than individual agency needs.” ~ President George W. Bush
The Federal Enterprise Architecture is helping OMB and agencies transform to meet the President’s challenge.
“The FEA is a powerful tool for identifying both key gaps and redundant efforts and can be used to determine the most effective investment in IT.” ~ Budget of the United States Government, FY 2004
With the FEA Without the FEA Agencies and budget examiners can leverage existing IT capabilities before spending new money Potentially redundant IT spending (e.g. $250 million on financial management systems) Standardized performance data to facilitate more objective, fact-based management Disparate, less than ideal performance information to make decisions (e.g. half of PART programs evaluated could not demonstrate results) Collaboration where possible visibility into agency operations for ALL agencies and budget examiners “ Stove-piped ” agency operations and budget allocation decisions (e.g. 50 agencies with federal drug control operations)
The Federal Enterprise Architecture (FEA) Performance Reference Model (PRM) “At-A-Glance.”
The PRM is a flexible resource for agencies to use as they build from their existing performance measurements.
The PRM can be integrated into the existing federal budget process, including the Exhibit 300 as required by OMB Circular A-11.
Agencies can use the PRM to select standard performance indicators—which may be new or coincide with those already in use—which can be tailored or “operationalized” to the specific environment.
HOW WILL THE PRM BE USED?
A PRM Working Draft is being released for agency comment.
The FEA-PMO will address agency’s comments and change the draft PRM as needed.
A PRM Version 1.0 will be released to use in FY 2005 budget formulation.
WHAT IS THE PRM’s STATUS?
The PRM can mutually reinforce and work together with GPRA and current PMA Budget and Performance Integration initiatives such as the PART and Common Measures.
A standardized performance measurement framework designed to:
Enhance available performance information,
Better align inputs with outcomes, and
Identify improvement opportunities across organizational boundaries.
WHAT IS THE PRM?
The PRM is a resource that can help agencies meet many of the existing legislative and policy requirements for performance. Integrate planning and managing for performance into budget justification and execution. Improve performance through technology. President’s Management Agenda Provide timely, reliable, useful, and consistent financial information for decision-making Chief Financial Officers Act of 1990 and other related Acts Plan and report progress towards outputs and outcomes Government Performance and Results Act of 1993 Make IT investments based on contribution to program performance Clinger-Cohen Act of 1996 Collaborative performance measures E-Government Act of 2002 PRM Existing Requirement
The PRM is consistent with and can help agencies make progress on many of the key performance initiatives that need improvements. The PRM framework can help improve and further relate outcome and output measures in Strategic and Annual Plans and Reports. Performance by function will facilitate producing the required government-wide Performance Plan. Government Performance and Results Act implementation The PRM framework can help to refine the relationship between outcomes, outputs and the processes or strategies used to produce them, and the inputs or resources used. This creates more robust information to use in budget decisions. PMA / Budget and Performance Integration If common measures have already been identified through other initiatives like the Common Measures they can be used directly by the PRM . Common Measures How PRM Can Help Initiative The PRM can be used to identify performance indicators that show specifically how a technology investment contributes to business outputs and, ultimately, outcomes. IT Business Cases (Exhibit 300) Progress towards PRM indicators can provide enhanced information to include in PART evaluations . PART evaluations can guide the improvement targets set using the PRM—particularly in lower-scoring PART programs. Program Assessment Rating Tool (PART)
The process to use the PRM is as important as the PRM itself. The FEA-PMO is suggesting a process that can be integrated into the existing performance and budget processes. Making improvements then tracking progress towards PRM Indicators to determine whether improvements are actually occurring. This performance information should then be a critical aspect of daily and strategic decision-making . Implement Improvements; Collect Data; and Use Performance Information in Decisions The scope and strategy of the improvement will be discussed through existing budget documents, including the Exhibit 300 required by A-11 . Select and Propose Improvements Possible strategies to achieve improvements targets will be identified, such as coordinating, creating or canceling processes or technology; sharing information and data; or retraining and recruiting people. Explore Improvements Considering the baseline and through benchmarking high-performers in the government and private sectors , agencies set improvement targets. Set Improvement Targets Within the context of the PRM Indicators chosen, agencies can conduct a baseline analysis of current performance, constraints, and capabilities . Conduct Baseline Analysis Informed by the “line of sight,” agencies can use the PRM to identify the critical few indicators . These indicators will be tailored or “operationalized ” to suit the specific IT initiative and its environment. Identify and Define PRM Indicators Agencies can use the concepts of logic models and the value chain to identify the critical cause and effect relationships between IT and process outputs, then to customer and mission or business outcomes. Determine Line of Sight to Results Description Step
The initial steps in this process will be of critical importance for agencies as they prepare to submit their FY 2005 budgets to OMB.
For FY 2005, agencies will identify PRM Indicators for their major IT initiatives in the Exhibit 300 performance goals table
More information on this suggested process will be available in the very near future
OMB A-11 training
PRM Version 1.0 release document
Consistent with Chapter 22 of the President’s FY 2004 Budget, the PRM can be applied to any major IT initiative. The level of PRM collaboration would correspond to each category as necessary. Initiatives that align with Human Resources Training and Development Initiatives that align with Border Security IRS Free File Example High Medium Low Level of PRM Collaboration Category of IT Initiative
Initiatives are common to all agencies or rise to a level of major policy significance and require PMC action to be successful
More than one-agency is involved and the initiative may require joint ownership and funding
One agency has the lead and the initiative can be implemented through the normal, agency-specific budget process
When one agency has the lead such as with the IRS Free File initiative, the PRM can be used to identify performance indicators from outcomes to inputs.
When more than one agency is involved, such as with Border Security, the PRM also can help identify indicators from outcomes to inputs.
For government-wide initiatives, such as the Resource Development and Training Sub-function of Human Resources, the PRM also can help identify inputs, outputs, and outcomes.
Over time, progress towards PRM indicators can provide a “performance dashboard” to inform managerial and budget decisions. Illustrative Example More thorough inspections may be necessary ... … but not so thorough to increase wait-time and reduce customer satisfaction Technology improvements could be explored and may allow more thorough inspections XX XX Baseline Target XX XX XX XX XX XX XX XX XX Actual XX XX XX XX XX XX Strategic Outcome(s) SECURE THE HOMELAND XX Customer Results Mission and Business Results Processes and Activities People Technology Other Fixed Assets # of crimes committed using illegally imported weapons Average wait-time at Border Inspection station # of vehicle searched performed per month % of total border inspector positions unfilled % downtime for Firearms Integrated Technology # of Border Inspection lanes available
Throughout all aspects, the PRM can help OMB, CIOs, CFOs, and Program or IT Project Managers in a variety of ways. Standardized information to identify similar programs or IT for “best practice” consultation or other collaboration Stronger justification of proposed initiatives and articulation of how initiatives contribute to outcomes Additional information to manage initiatives and demonstrate contribution to outcomes Program / IT Project Managers Standardized information to identify potential cost savings and performance improvements Better articulation through GPRA of how budgetary resources and inputs contribute to outcomes Additional information to use in GPRA and budget activities CFOs Standardized information to help identify collaboration opportunities within and outside the agency More clarity about what IT initiatives to select and how they will/are contributing to results Additional information to use in IT Capital Planning and Investment Control activities CIOs Standardized information for programs and IT initiatives with common or similar missions More detailed information about how IT will contribute to outcomes Additional information to include in budget decision-making activities OMB Identify Improvement Opportunities Across Boundaries Alignment and Clear “Line of Sight” Enhanced Performance Information
Consistent with existing processes, the PRM can help agencies better manage their IT initiatives.
Using the PRM will provide more robust performance information for agencies to use throughout their IT CPIC processes
Pre-Select / Select - Better understanding of how IT may contribute to improved program performance
Control – More robust information about progress towards intended outputs and outcomes to inform decision-making
Evaluate – More structured framework to assess whether IT initiative provided its intended benefits
The PRM can also be a path forward to help agencies better align their EAs with performance
Align business layer with key outputs and outcomes
Align key technology initiatives with business layer, and by extension, outputs and outcomes
The PRM can support the President’s Budget and Performance Integration initiative, which is taking two approaches to strengthen the link between budget dollars and results. HOW: Program Assessment Rating Tool (PART), which rated 50% of the programs assessed as “Results Not Demonstrated” Creates additional performance information at the outcome, output, and input levels to use in budget decisions WHAT: Creating additional performance information to inform budget decisions How the PRM Can Help Budget and Performance Integration Approach #1 HOW: Developing a performance budget format that shows how inputs are used to accomplish outputs and impact outcomes Draws “line of sight” from inputs to outputs, then outcomes WHAT: Linking performance and cost in the federal budget How the PRM Can Help Budget and Performance Integration Approach #2
Annual Performance Reports Annual Performance Plans PRM Indicators can be incorporated into GPRA plans and reports. Outcome-oriented indicators in GPRA can inform those in the PRM. Performance information by function can also support the government-wide performance plan GPRA requires. Strategic Plans GPRA Requirements
STANDARD AND IMPROVED MEASURES
Outcomes / Intermediate Outcomes
The results of PART evaluations can dictate the specific PRM indicators and targets agencies use to drive improvements. Program Assessment Rating Tool (PART)
Program Purpose & Design
The PRM can be applied to help improve the management capabilities and performance of lower-scoring PART programs with similar missions
Defining standard and improved indicators using the PRM can also provide enhanced performance information to use during PART evaluations.
PART evaluations can be complemented with more readily available, standardized, and improved performance measurement information
50 % of FY 2004 PART assessments “Results Not Demonstrated”
Specific PART questions that can be informed include:
The extent to which the program meets its performance targets compared to similar programs IV: Program Results, Question 4: Does the performance of this program compare favorably to other programs with similar purpose and goals? Whether the program meets the performance targets chosen in the outcome portion of the PRM IV: Program Results, Question 1: Has the program demonstrated adequate progress in achieving its long-term outcome goal(s)? The extent to which similar programs choose common PRM indicators II: Strategic Planning, Question 4: Does the program collaborate and coordinate effectively with related programs that share similar goals and objectives? The PRM Will Provide Enhanced Information About … PART Section / Question
OMB Circular A-11, specifically Section 300, provides the mechanism to integrate the PRM into the existing management and budgetary process for IT.
The FEA-PMO is currently working within OMB to update the Exhibit 300 to accommodate the PRM
Detailed information will be provided to agencies about this at OMB’s A-11 training to be held in early May


Despite claims to the contrary Australia's plans to join a
ballistic missile defense system will certainly affect China's
security and may be targeted at the nation, warn analysts.
Australia said on Tuesday that it is considering taking part in
the US and Japan's missile defense system, to counter new threats
including Pyongyang's missile arsenal. The announcement followed
diplomats' carefully stressing that the system was not designed to
check Chinese influence.
But Zhang Qinsheng, deputy chief of the general staff of the
People's Liberation Army, had already made China's opposition to
the missile defense system clear at the Asia Security Summit in
Singapore last week, pointing out that with the system covering
Taiwan it would bring instability to Asia.
Jin Linbo, a scholar with the China Institute of International
Studies, said the system would definitely affect China.
"We cannot regard it as a defensive system just because that's
what it is called," Jin told China Daily. "Since ancient
times both spears and shields have been regarded as weapons in
Chinese culture - because shields can make spears useless.
"In this regard, worries about the missile defense system are
the same as concerns about other weapons."
Researcher Pan Zheng, of the PLA University of National Defense,
questioned Australia's motives for cooperating in the missile
"The six-party talks (on Pyongyang's nuclear program) have made
great progress and are still working towards a brighter future.
Meanwhile the US and North Korea have established channels for
direct high-level dialogue," said Pan, "I cannot see the necessity
for military expansion targeting North Korea at this time.
"In my opinion, it is more focused on curbing China."
(China Daily June 8, 2007)


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Illinois is bleeding red ink, yet our representative keep spending taxpayer money at well.
The City council of Chicago gave President Obama 19.3 acres of prime property in Jackson Park to build whatthey thought was a library.President Obama Foundation pays $ 1, rent in perpetuity. We the taxpayers willfoot about 300,000 $ to build roads from and to the so called library. Sure enough President Obama can pay the billwith a couple speeches and save the tax payer..The Chicagoans imagined they will be getting a Presidential library akin to President Reagan in California, orPresident Kennedy in Boston.. But unlike those libraries the Obama Center will not be run by the NationalArchives and Record Administration. It will not even house Mr. Obama's records or paper. It will be run by the "Obama Foundation..In 2014 the request by the Obama Foundation in there proposal said the planned library "will include an Institute that will enhance thepursuit of the President's initiatives beyond 2017."The Chicago Tribune reported in Feb " Obama said he envisions his center as a place where young people from around the world to meet each other, get training and prepare the next generation leaders" !!No doubt his definition of "leaders " will be political.Mayor Rahm Manuel said "money well spent" (he was Obama's first chief of staff.Where is the outrage?, when did the PJS comment on this. And when are our representative be accountable?Rida W . Boulos, MD.Peoria


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Home > Places > Idaho > Franklin County > Lakes > Gibson Lakes
Gibson Lakes Fishing, Franklin County ID
Elevation: 8,461 ft (2,579 m)
USGS Topo Map: Mapleton
Fishing Location Type: Lake
Nearby Fishing Spots
Gibson Lakes Idaho fishing map and location information: Gibson Lakes is a Lake in Franklin County, Idaho and can be found on the Mapleton USGS topo map. The GPS coordinates for this Lake are 42.0367527 (latitude), -111.6301104 (longitude) and the approximate elevation is 8,461 feet (2,579 meters) above sea level. Anyone interested in fishing Gibson Lakes or nearby fishing Lakes should consult with guides and other local resources before heading out to fish. Anglers who are familiar with Gibson Lakes are asked to submit reviews of the Lake. Is Gibson Lakes open to fishing, and if so, what can you catch there?


When Dr. Rajesh Kumar meets his patients for the fist time, they can often fit into the palms of his hands.
Kumar is a medical specialist who cares for tiny infants in Jharkhand, the largely rural Indian state located west of Kolkata. Jharkand has 33 million residents, but just a few doctors like Kumar. On any given day, Kumar’s team of twenty pediatricians and neonatologists working at the Rani Children Hospital in the state capital of Ranchi have up to 100 newborns in their care. Some weigh less than two pounds at birth. The babies sorely need modern medical technology to grow and get better, but it had been slow to reach them.
Things started changing three years ago, when Kumar’s neonatal intensive care unit installed new Lullaby baby warmers and photo-therapy technology developed by GE in India specifically for the rigors of the local market.
The units are not the same high-end machines you might find in an American hospital, but sturdy and more affordable clones. In Jharkand, for example, the annual per capita income is just $680 and working electricity is not always a given.
Coming up with the right design required a new kind of insight. "You can’t take a product and simply strip it down and replace expensive parts with cheaper ones,“ Vikram Damodaran, director of healthcare innovations at Wipro GE Healthcare recently told The New York Times. "It has to come from the ground up, with a lot of input from the people who might actually use it.”
On a typical day, the Rani Children Hospital is using GE technology to care for as many as 100 tiny patients. Top image: GE’s Lullaby phototherapy system.
The Lullaby warmers are helping Kumar’s tiniest patients maintain their body temperature. The GE engineering team redesigned the machine’s controls and included buttons with intuitive icons and dials to give nurses more time to focus on the baby, rather than switches.
The Lullaby warmers work in combination with Lullaby phototherapy systems, which were also re-engineered by GE. Doctors use them to treat infants with neonatal jaundice, a common illness caused by their immature livers. Left untreated, the yellow byproduct of dying blood cells called bilirubin can build up in the body and damage the developing brain. Without phototherapy, they would have to receive blood transfusion but the technology helps the tiny bodies to get rid of the substance.
Dr. Rajesh Kumar is using redesigned GE medical machines to care for his patients.
Engineers working at GE’s research center in Bangalore, India, equipped the new phototherapy machines with special LED lights that can last almost six years, or 50,000 hours, 25 times longer than standard fluorescent lamps that use five times as much electricity. “Technologies like low cost baby warmers and LED phototherapy systems can help save many newborn lives every day, especially in a country like India,” Kumar said.
Hospitals in Europe like the simplified functions so much that they have placed their own orders for the redesigned machines. "There has been a shift,“ Shyam Rajan, chief technology officer at Wipro Healthcare, told the Times. "Before, it was India for India. Today, it is India for the World.”


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1. United Nations General Assembly
This is the 73rd UNGA, where world leaders get together in New York City to discuss and vote on major global issues. It’s the perfect time to reset, refresh and write down new goals, right? The UNGA opened yesterday and will last for three months. On September 25, the General Debate will begin, in which each member state of the United Nations is invited to speak for 15 minutes. It is an opportunity for nations to address the international community and is often used as a way to air grievances.
María Fernanda Espinosa, the president of the 73rd Assembly, opened her speech on Tuesday with the intentions of her year in office. She said that the need for stronger global leadership in the service of multilateralism, to ensure more peaceful, equitable and sustainable societies, would be the focus of her work. She outlined her seven priorities for the year that will shape the year-long session: promoting gender equality; promoting and implementing the new global compacts on migration and refugees; advocating for decent work; protecting the environment; focusing on rights of persons with disabilities; supporting the UN reform process; and facilitating dialogue. Justin Trudeau is amoung the members as well as President Trump. Those who took a hard pass are Vladimir Putin and China’s Xi Jinping.
2. North & South Korea’s Deal
If this handshake isn’t an example that people deserve second chances, we don’t know what is. North Korean leader Kim Jong Un and South Korean President Moon Jae-in have come to an agreement that North Korea will start taking steps to denuclearize. Although there are no clear details on how it will happen, Kim Jong Un did say he will permanently shut down the Tongchang-ri missile launch and engine testing facilities with independent inspectors present. He also said he is prepared to permanently shut down his nuclear production facility at Yongbyon, but only is the US takes “reciprocal steps” reflecting on the agreement he signed with the US on June 12. The reciprocal steps were not outlined. President Trump took to Twitter to express his opinion on the deal. He said that Kim had allowed nuclear inspections “subject to final negotiations” (something that was not mentioned by the Koreas on Wednesday) and highlighted that the two Koreas will also submit a bid to host the 2032 Summer Olympics. He didn’t mention the required reciprocal steps.
“This summit contributed in breaking down walls between Koreas — a real process for both North and South Koreans,” John Delury, a North Korea expert at Seoul-based Yonsei University, told ABC News. “People want something new. Obviously, Kim coming to Seoul is new.”
3. Superbowl Halftime Show
Even though it hasn’t been officially announced by the NFL, Twitter became a frenzy when speculations about Superbowl LIII’s halftime show involved Maroon 5. A league rep said that it is part of the Superbowl tradition to get people excited about the official announcement by encouraging speculation. People were less than impressed with the chosen band. Atlanta is a music-rich city with a long list of top artists that could have been chosen instead. In a tweet, sports analyst Jake Reuse said, “Atlanta, home of Outkast, T.I., Future, Ludacris, Usher, etc., gets Maroon 5 to play the damn Super Bowl.” This was a reoccurring opinion of most people, even though people really like Maroon 5, they don’t feel like it best represents Atlanta; a city that has roots in hip hop. Ludacris, rapper and Atlanta native, posted a photo on Instagram wearing an Altana Falcons jersey with the caption, “Excuse me say what!?”
4. Facebook’s Fake News Tool
Facebook is rolling out a new tool in Canada for users to detect fake news. There will be a new button on the news feed that will let Canadians evaluate the credibility of the news and source. When pressed, the button will lead to the poster’s Wikipedia entry, related articles on the same topic and information about how many times the article has been shared on Facebook and where it is has been shared. It will also show other articles the user has posted, show which friends have also shared the post and how old the article is. After the Cambridge Analytica fiasco, Facebook is putting in extra effort to stifle the spread of fake news on its platform.
The feature became available for Americans in the Spring but has finally made its way up to Canada. You’ll start to see a little “i” which will provide you with all the info. This will hopefully help the spread, giving users the ability to watch out for fake news rather than just Facebook employees.
5. 4D Theatre Coming to Calgary
If 3D isn’t enough for you, get ready for a whole new experience when watching a movie. Yesterday, Cineplex announced its plans to open a 4DX auditorium at the Chinook Centre. The first of these theatres opened in Toronto in 2016, this will be the second in Canada. The timing of the theatre will be announced in the coming weeks according to Cineplex. Sarah Van Lang speaks for Cineplex and she’s promising a full sensory experience. “They’re sitting in a chair that moves in concert with the action on the big screen and then there are all these other atmospheric effects going on around you — so there’s snow, there’s rain, there’s mist, there’s fog. If the mood strikes, there’s sometimes bubbles,” she said. Cineplex’s long term plan is to open up 13 4D theatres across Canada within the next few years. Stay tuned for an epic movie watching experience.


I have a problem with the module "mod_tz_multipurpose" at the team presentation!
Up to five people it is displayed correctly, only when the sixth person is moved in the line and is displayed very small!
I have now installed the Quickstart for the third time so it runs the demo Quickstart version, even with Joomla 3.8.2.
Do you have the same problem and do you have a solution for it?
Many thanks and best regards