DAVE KING would be ‘surprised’ if Rangers don’t do some transfer business in the upcoming January window.
After a hugely successful transfer period in the summer with no-less than 15 new arrivals to the squad, King believes that tally could rise even further over the winter.
Speaking at this afternoon exclusively to RangersTV following the club’s AGM, the chairman explained: “I would be surprised if we don’t do some business in the January transfer window. Speaking to Mark [Allen] and the manager, they are very alert to sometimes the fact sometimes the long-term quality of player is maybe not available in January.
“But I wouldn’t be surprised if we did some business, but it will only be done if we think we can improve the overall value of the squad and the right player is available in January. It’s not going to be done just for the sake of it.”
King also insisted the arrival of any new player would not be dependent on a player or players heading in the other direction.
“They wouldn’t have to leave,” he added. “If the manager gave an argument to say ‘I would have taken the player in the summer anyway – let’s bring him in early as opposed to the summer’ – I think we would look at that as well.
But it is important to get a balance as the squad is still quite large at the moment. I think even the manager recognises we probably do have too many players in the squad so we are going to have to look at trimming it down in any event.”
The work done over the summer by Steven Gerrard, Allen and the staff at the Hummel Training Centre has greatly impressed and pleased the chairman, and he feels the money put up by himself and the rest of the club’s investors has been wisely spent.
King continued: “I think the guys have done a fantastic job and if I look, certainly for the first time since regime change, at the value in the squad, then I think the economic value of the squad is far greater than the carrying value on the balance sheet whereas in previous years, we paid for players at values where we wouldn’t get the money back.
“So the opposite is true and I am certainly feeling a lot more confident about the economic value we have got of the players, which means when we are rotating them, we are going to get better value on the players going out which helps us with the players coming in.
“I would say we are ahead of the game in the sense that having made the investment and looked at the players we are bringing in; I think he brought in 15 players if I remember correctly and I think it is fair to say only one of the 15 probably hasn’t worked out, so that is a great return in terms of the identification of the right quality of player.
“I think the proof is on the park, and certainly at the beginning of the season, if you had offered me after four very, very tough qualifying rounds looking ahead to that and saying we would be in the Group Stages and playing Villarreal in a big game at home and have a chance to go through, I would absolutely have taken that.
“So we are ahead of where my realistic expectations would have been.”


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Monday, May 18, 2020
Results of the Putt18 4 Nations Cup
We played in the first Putt18 4 Nations Cup international miniature golf tournament at the weekend.
The event saw us compete for the UK against pairs from Australia, New Zealand and the USA.
Each player had a 16-minute time limit to play four 18-hole rounds for a 72-hole total score.
The event was won by the New Zealand team of Cameron Couper and Matt Ansley with an 8-round total of 572.
The Australian duo of Josh Mars and Nathan Lamplough were runners-up with a total of 583.
The USA team of Pat Sheridan and Tom Loftus were in third place with a total of 604.
Emily and I shot an 8-round total of 656. Not too bad considering we only had a day to practice!
The low round of the event was shot by Australia's Josh Mars with a score of 65.
We're looking forward to playing some more competitions and friendlies on the Putt18 game mat. We'll be trying out the set in different spots around the house to find the optimum putting surface too.
You can watch each player's four rounds in the videos below.
Labels: Australia, Competitive isolation, competitive socialising, Game, indoor putting game, Miniature Golf, Putt 18, Putt at home, Putt18, Putt18 Golf Putting Mat Game, Putting, quarantainment, quarantinement
Location: United Kingdom
I’m a Champion Miniature Golfer on a tour of the UK’s minigolf and crazy golf courses. Coeliac living a gluten free life. Train nerd. Retro gamer. Urban explorer.

domain: sports


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Cdk5 Recombinant Rabbit monoclonal Antibody IgG
Fig1: Western blot analysis of Cdk5 on Hela cell lysates using anti-Cdk5 antibody at 1/500 dilution.
Fig2: Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-Cdk5 antibody. Counter stained with hematoxylin.
Fig3: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-Cdk5 antibody. Counter stained with hematoxylin.
Host Species; Species ReactivityRabbit; Human, Mouse, Rat
Application SummaryWB, IHC, IP, FC
Purification; FormulationProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesCyclin-dependent-like kinase 5, Cell division protein kinase 5, Serine/threonine-protein kinase PSSALRE, Tau protein kinase II catalytic subunit
BackgroundCell cycle progression is controlled in part by a family of cyclin proteins and cyclin dependent kinases (Cdks). Cdk proteins work in concert with the cyclins to phosphorylate key substrates involved in each phase of cell cycle progression. Another family of proteins, Cdk inhibitors, also plays a role in regulating cell cycle by binding to cyclin-Cdk complexes and modulating their activity. Several Cdk proteins have been identified, including Cdk2-Cdk8, PCTAIRE-1–3, PITALRE and PITSLRE. Cdk5 is thought to be involved in the G1-S transition of the cell cycle and is highly expressed in mature neurons. Activity of Cdk5 increases significantly during neuronal differentiation. Cdk5 has been postulated to be a neurofilament or tau protein kinase, based on its ability to phosphorylate these proteins in vitro.(ET1602-17)

domain: biology


text:
as part of the on-going simplification of the site, we’ve moved the Clash of Code contributions to the community tab.
Soon the pending puzzles contributions will follow and be moved to the community tab as well. Indeed the puzzles page is being reworked, so it will be released at the same time.
And if some don’t see the tab Clash of Code, it’s totally normal, we’re conducting a few tests. It’s available from the home page anyway.
I forgot to tell something (thank you @simon_landry): for those who don’t have the Clash of Code tab, there is just one mode now, flash (5 minutes) for which you have still maximum 15 minutes to code.
If you’ve got questions, don’t hesitate

domain: hobby


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Our reviewers evaluate products and services based on unbiased research. Top Consumer Reviews may earn money when you click on a link. Learn more about our process.
Traveling is a favorite pastime of many people. Seeing the world is one of the most rewarding things that can be done in life. Before traveling abroad, many things need to be put in order so that everything goes smoothly and the trip can be enjoyed to its fullest.
Getting a passport is usually the only thing people think of needing before hopping on a plane to a new country. It's important, however, to realize that many countries also require travel visas to enter their country for tourism or business.
Friday, March 24th
iVisa is a great place to find travel visas because of their extensive list of destinations. Their application process is extremely easy and straightforward. Customers who have gone through iVisa are satisfied and happy with their services. Tens of thousands of people have used iVisa for travel visas, making it one of the best online services out there.
Passport Visas Express is a great company for obtaining travel visas as well as passports. Thousands of travelers use their services and have smooth, hassle-free experiences. Pricing as well as documentation requirements for individual countries is straightforward here. This is an affordable and reliable option for all people looking to travel abroad.
VisaHQ provides prompt, reliable passport and travel visa services. Everything is done online and through the mail, so customers don't have to visit any embassies or consulates to fill out paperwork. They receive high ratings from both national news outlets as well as individual customers. VisaHQ has transparent, fair pricing, so we highly recommend their services.
Travel Visa Pro is the place to go if you want excellent customer service when obtaining a passport, visa, or other international documents. They have a customer base of extremely satisfied users who felt their needs were met and that Travel Visa Pro paid extreme attention to detail in their paperwork. We found Travel Visa Pro to be a bit more expensive than some competitors, but their pricing depends on the destination, processing times, and embassy fees. Overall, they are a good option for obtaining a travel visa.
RushMyTravelVisa works with customers to obtain travel visas as soon as possible. They boast that their services are the fastest way to get a travel visa without having to attend any in-person appointments at a consulate or embassy. Their parent company receives a C+ rating from the Better Business Bureau and they have mixed customer feedback. Because of this, they have earned an average rating from us.
Travisa, like most of their competitors, deals with both travel visa processing and passports. Customers can fill out forms online, but will need to physically mail in required documentation to an address provided by Travisa. We found that customers are generally satisfied with their visa turnaround times and customer service experiences here. We would like to see more about the company on their website and have access to more robust features, as well as transparent pricing.
If you've never done the paperwork for a travel visa, this might seem like an overwhelming and stressful task. You want to make sure all your legal bases are covered and done in a timely manner so that you can travel abroad without issues. Luckily, there are travel visa companies that know the ins and outs of helping people complete everything they need before their big vacation. Rather than taking the time to visit a brick-and-mortar travel visa agency, you can easily complete the process online.
Some common pieces of information that are usually needed for a travel visa application include a letter of invitation (from the traveler's host confirming they will accommodate the traveler), photocopy of passport, travel insurance, proof of financial support abroad, airplane ticket, proof of purpose of travel, and visa application fees. These pieces of information are usually sent to the country of travel and approved by a visa officer there.
When planning your next trip abroad, consider the following things to ensure you get your travel visa taken care of quickly, efficiently, and reliably:
TopConsumerReviews.com has reviewed and ranked the best travel visa companies available today. We hope these reviews help you get a travel visa lined up online before your next trip!
Select any 2 Travel Visa Services to compare them head to head
NBC News on MSN
Mother of soldier found dead in Fort Hood granted humanitarian visa ...
The Mexican mother of a soldier found dead at Fort Hood in Texas is planning to come to the U.S. and await the outcome of an investigation on her daughter's death, according to the family. Alejandra ...
Thu, 23 Mar 2023

domain: travel


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Youth Media Resources | Audio
WSKG is proud to host a variety of youth media programs for our community. This resource page was assembled specifically to assist participants of An Ear For Drama but any young media maker is welcome to check out the links below.
BBC Writers Room | Radio plays are alive and well on the BBC. The online tools found in 'Scriptwriting Essentials' are a great place to start for the novice dramatist! We recommend this downloadable PDF template to use as a guide for your script! Creative Commons|A new system, built upon current copyright law, that allows you to legally use “some rights reserved” music, movies, images, and other content — all for free. Teacher Resource Guide | We've created an easy-t0-implement project guide for this project. Click to view the PDF and email firstname.lastname@example.org if you'd like the PowerPoint version.Musopen | Free recordings of classical music. Radio Drama Revival | This is a go-to source to listen to radio dramas and also includes a five-step 'how to' section for those interested in creating their own production. Reality of Digital Drama | Students discuss their impressions of of real-life peer drama, both online and as depicted on reality TV. This resource comes from Common Sense Media and is helpful if your group if choosing to write a story about challenging social situations amongst teens. Royalty Free Music | A website featuring royalty-free music, stock photos, clip art, video footage, and more. Soungle | Searchable database of sounds, no attribution necessary. The Moth | Since its launch in 1997, The Moth has presented thousands of stories, told live and without notes, to standing-room-only crowds worldwide. Moth shows are renowned for the great range of human experience they showcase. Each show starts with a theme, and the storytellers explore it, often in unexpected ways. This American Life | This weekly public radio show is broadcast on more than 500 stations to about 2.2 million listeners. It has won all of the major broadcasting award is also often the most popular podcast in the country, with another 2 million people downloading each episode. This is a great place to start your listening adventures if you are new to radio drama. Youth Media Reporter | An open access, peer-reviewed professional journal for scholars, practitioners and others who develop, organize, teach, study and support youth media practices and programs.

domain: library


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Controversial news anchor who blasted Beyonce for 'politicising' the Superbowl's half-time show refuses to allow the singer to use a clip of her rant during her world tour
- Tomi Lahren launched an online rant against Beyonce after the Superbowl
- She accused the singer of politicising the show for her own personal gain
- Beyonce has now asked Lahren for permission to use a clip of her rant
- But the online news anchor has told the singer she won't give permission
- For the latest Beyonce updates visit www.dailymail.co.uk/beyonce
A conservative online news anchor who has become well-known for her controversial views has reportedly refused to licence a clip of her YouTube video to Beyonce for her forthcoming world tour.
Tomi Lahren, 22, provoked outrage earlier this year when she ranted on online news network The Blaze about the popstar's Superbowl performance.
Beyonce's half-time show at the Superbowl in February featured the singer with a troop of dancers appearing to pay homage to the Black Panthers movement and its modern day successor - Black Lives Matter.
Controversial online news anchor Tomi Lahren, left, who has refused to let Beyonce, right, use a clip of a rant against her Superbowl half-time performance earlier this year
After the show, Lahren, who lives in San Diego, originally took to The Blaze's YouTube channel, where she recorded a video ranting at Beyonce for politicising the half-time show.
She explained that the show 'ripped off an historical band aid' on America's civil rights movement by promoting the Black Panthers.
Scroll down for video
Lahren also added: 'This isn't about equality, this is about ram roding an agenda down our throats and using fame and entertainment to do so.'
Now, according to TMZ, representatives for Beyonce contacted Lahren asking for the rights to use the first 30 seconds of the clip during the Formation world tour.
Lahren originally took to The Blaze's YouTube channel, where she recorded a video ranting at Beyonce for politicising the half-time show
Lahren explained that the show 'ripped off an historical band aid' on America's civil rights movement by paying homage to the Black Panthers
But despite saying they only wanted to use the audio of the rant Lahren told the singer's camp she would not give permission for the rights.
After her rant against the popstar Lahren was faced with abuse on social media, with some labelling her as racist, but she refused to apologise.
The 22-year-old first went viral last year when she released a video of blasting President Barack Obama's efforts in the fight against terrorism.
She called out Obama's administration for their 'half-way, half-baked, tip-toe, be-friendly-to-Jihadis mentality' in a passionate speech that has been viewed more than 755,000 times on YouTube.
The 22-year-old first went viral last year when she released a video of blasting President Barack Obama's efforts in the fight against terrorism
It was later revealed that the rant was inspired by her military officer boyfriend Jerad Christian, who had told his girlfriend he wanted to do more to keep U.S. service members like him safe.
Lahren was born and raised in South Dakota, where she was student body president at her high school.
She attended University of Nevada, Las Vegas, and graduated with degrees in journalism and political science.
After graduating in 2014, she moved to San Diego to work with One America News.
She also made headlines last March after giving a speech at the Conservative Political Action Conference where she criticized the misconception among young people thinking the GOP was filled with 'old, rich, white males'.
Most watched News videos
- President Trump barges his way to the front of NATO meeting
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- Armed soldiers spotted across London after Manchester attack
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- Homeless man describes how he helped after Manchester attack

domain: news


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A Moment to Change the World: The Sydney Peace Prize Story
Human rights are for everyone, equally, universally, and forever. Unfortunately in today’s world, many people are denied a life in dignity. The challenges to peace and justice are daunting, but now is not the time to falter.
2017 will mark the awarding of the 20th Sydney Peace Prize. In celebration of this milestone, the Sydney Peace Foundation’s supporters and Prize recipients have come together to help tell the story of the Sydney Peace Prize.
In our new video “A Moment to Change the World: The Sydney Peace Prize Story,” members from the peace community discuss the importance of peace with justice, nonviolence, and respect for human rights in today’s challenging climate. This video conveys the power of the Sydney Peace Prize to amplify messages of inspiring peace leaders and unify our diverse communities in the pursuit of peace with justice.
Featuring contributions from Sydney Peace Prize recipients Naomi Klein, Julian Burnside AO QC, and Senator Patrick Dodson, Missy Higgins, Australian Human Rights Commission President Professor Gillian Triggs, Lord Mayor of Sydney Clover Moore, students from Cabramatta High School, the Foundation’s Founder Stuart Rees, Director Lisa Fennis, and Chair David Hirsch.
Let’s come together, let’s take a stand against intolerance, hatred, and fear mongering. Let’s celebrate our shared values, and our common humanity.

domain: sociology


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The Spain-Ghana Chamber of Commerce (SGCC) is a private association with a main aim, which is to promote and increase bilateral relationships between Spain and Ghana, offering a wide range of services to support companies in both markets.
SGCC will send you a quarterly newsletter with updated news and information.
Within our team we have qualified members to support your business.
Our team will organize an agenda according to your needs.
Our team will promote and represent your business interests.
Data from the Ghana statistical service has revealed that the
The third annual edition of the Digital Quality of Life
The Minister for Trade and Industry, Alan Kyerematen, has admonished

domain: economics


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Hillside Laguna Beach LLC
Hillside Laguna Beach LLC is a drug and alcohol rehab based at - - - in Laguna Beach, California. Hillside Laguna Beach LLC can be contacted at 310-445-5743.
The main approaches to treatment at this program include Cognitive Based Behavioral Therapy, Relapse Prevention Plans, 12-Step Support Group Therapy Approach. The program also provides their services in different environments, such as Inpatient Recovery and Treatment , Short Term Rehabilitation, Long Term Rehab, Residential Detoxification.
Hillside Laguna Beach LLC also offers various programs that are customized to meet the needs of specific people such as: Alcohol Rehab for Lesbian, Gay, Bisexual, Or Transgender (LGBT) Clients, Drug and Alcohol Treatment for Adult Women, Aftercare Programs, Substance Abuse Assessment, Mental Health Recovery Services. Finally, Hillside Laguna Beach LLC accepts various payment types, such as Private Pay, Private Insurance for Drug Rehab , Payment Assistance (Check with Facility for Details).
We can help you find the right treatment facility that best fits your overall needs and financial requirements.

domain: medical


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I hate the way democracy gives more right to minority groups on the expense of the whole.
I hate the need to be politically being correct. (or else! one slip of the tongue and the whole pretend system is after you!) Eg: talk carefully about the environment, religious, racial, sexual - age & gender issues.
I hate the greed of the state, the corporation and the individuals. The governments constantly increasing fees and taxes without to consider if one can afford to pay it or not! Corporation and business are charging prices based on how much they can extort from someone not based on the actually value they provide. Individuals who are inconsiderate of others for their own benefit.
Governments who are not regulating industries who scamming you to rip you off. Eg: Phone companies should be in the telecommunication business and not in the money collection business for the behalf of other businesses. ( Advertisement in the TV, asking a very simple question, or even displaying the answer in the background. You know the answer? Call xxy number with your answer for the chance to win $4000.00 ! And when the gullible call, than from the next phone bill going to find it out, that there were a $6.00 subscription fee, a dally $2.00 participation fee and the scam is going on until he / she don't call an other number to cancel the privilege to be in the draw for the $4000.00.) This is just one of the multitude of scams where the Phone Co. prepared to collect money for a small windfall for them self, and they calling it a "service" for the consumer!
I hate the right of "The Big Brother's" to control what the individual people are looking or reading on the computer (censorship).

domain: finance


Agenda items related to the proposed $6.5 million bond for the reconstruction of Congers Elementary School will be voted on by the Clarkstown Board of Education tonight. The board approved putting the bond to a public vote at its last meeting. The public referendum on repairing the school, which was closed in August, may be scheduled for early February.
Board members will be voting on the district’s withdrawal from the Race To The Top federal grant program. Superintendent Dr. J. Thomas Morton recently said the state education department has provided little information in response to questions raised by the district about protecting students’ information. Read his earlier comments here.
The board will approve the official results of the New City and West Nyack libraries’ budget vote on Wednesday. The combined budget for both libraries passed. The New City Library budget did not include an increase while the West Nyack Library budget rose by 1.7 percent. Unofficially 1,062 people cast ballots and an additional 22 submitted absentee ballots.
A resolution to fund a demographic study of the district will be brought up again. A motion to spend approximately $19,000 to forecast the district’s future enrollment was voted down at the last meeting.
Rockland County School Boards Association Executive Director Pam Frederick and President David Gammerstorf will give a presentation on their association’s function and purpose.
Board members will vote on accepting the following donations:
- Furniture for a radio desk at Clarkstown South High School contributed by WMCA 570 and valued at $5,000
- $4,262 for eight Nexus 7 Tablets for the Clarkstown North Physical Education Department, five Nexus 7 Tablets and camera stands for the North Art Department and three iPads for the North School Counseling Center contributed by the PTSA
The meeting begins at 8 p.m. at the Chestnut Grove District Offices at 62 Old Middletown Road in New City.


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Fuel plays a crucial role in Zambia as it influences the prices of goods and how the government handles its finances. Currently, Zambia, under the leadership of the UPND, is confronting a significant challenge as fuel prices are rapidly increasing. This trend is not limited to fuel alone but also extends to essential commodities like mealie meal, making life more difficult for ordinary citizens and raising concerns about the situation.
Acting PF Media Director, Edwin Lifwekelo, explained in a statement that the issue with high fuel prices is their negative impact on people’s ability to afford essential items. When fuel prices rise, individuals have less money available to spend on necessary goods and services, which, in turn, has detrimental effects on businesses and the overall national economy.
Moreover, businesses that heavily depend on transportation, such as delivery companies, are experiencing increased operating costs. To offset these expenses, they are forced to raise their service charges, resulting in higher costs for consumers when purchasing various items.
Mr. Lifwekelo highlighted that the soaring fuel prices have a ripple effect, causing the prices of various goods to rise as well. This situation places significant hardships on people, leading to frustration and sometimes public anger towards the government’s perceived inaction. The impact goes beyond anger; it’s about individuals facing financial difficulties and struggling to meet their needs.
Furthermore, the agricultural sector, a cornerstone of our nation’s economy, is also taking a hit from these elevated fuel prices. Farmers depend on fuel for their machinery and transportation, and when fuel costs escalate, it drives up the expenses associated with farming. Consequently, this has implications for the cost and availability of food, affecting both farmers and consumers alike.
Mr. Lifwekelo points out that although efforts are being made to adopt cleaner and more efficient energy sources, challenges persist. Fluctuating exchange rates are affecting our ability to trade with other countries and maintain a stable economy, making the situation more difficult to manage.
Mr. Lifwekelo emphasizes that the situation in Zambia is extremely concerning. The people of Zambia deserve leaders who prioritize their well-being and take action to address the challenges they face. He urges that it’s time for a change and for the people to make their voices heard before the situation worsens and becomes even more difficult to resolve.


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"We took our car to get fixed and came back to it being DAMAGED (bumper had to be completely replaced)! The car was in the shop for 10 ..."
"This place has the worst service!! I purchased tires there and 4 days later I got a flat on one of them. The independent body mechanic who put ..."
"Firestone has lost me as a customer for life. I took my car in for a simple repair of a slow leak in my tire. Firestone told me ..."
"I went for the oil change and free brake inspection. As soon as I left the bodyshop my car started making sound from the front wheel. I notified ..."
"Avoid this place like the plague!!! My husband took his car there to have them do a radiator service, and they disconnected something that made the "check engine" ..."
"I cannot speak for bad experiences of other customers but one thing i can say is that my own personal experience at the pep boys in San Fernando, ..."
"It's the worst Walmart I've ever been to...over priced...poorly stocked...over crowded, especially the parking lot. There is a Kmart on Sherman Way near Coldwater, which is way better. ..."


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Study Examines Aspirin Use to Prevent Colorectal Cancer
The U.S. Preventive Services Task Force concluded that aspirin reduces the risk of colorectal cancer by 40 percent as well as recurrence of advanced polyps.
Colorectal cancer is the third most common cause of cancer deaths in the United States and advanced colorectal polyps are a major risk factor. The U.S. Preventive Services Task Force (USPSTF) concluded that aspirin reduces the risk of colorectal cancer by 40 percent as well as recurrence of advanced polyps. Their guidelines suggest that, without a specific contraindication, health care providers should routinely prescribe aspirin to all patients with advanced colorectal polyps.
To explore whether patients are adhering to these USPSTF recommendations and guidelines, researchers from Florida Atlantic University’s Schmidt College of Medicine analyzed data from structured interviews on 84 patients, ages 40 to 91 years old, with biopsy proven advanced colorectal polyps between July 1, 2013 to June 30, 2017. The data, which were published in the American Journal of Medicine , showed that only 36 (42.9 percent) of the 84 patients with advanced colorectal polyps reported taking aspirin.
“These data indicate underutilization of aspirin to prevent colorectal cancer as well as recurrent polyps in these high risk patients,” said Charles H. Hennekens, M.D., Dr.P.H., senior author, the first Sir Richard Doll Professor, and senior academic advisor in FAU’s Schmidt College of Medicine.
Co-authors include the first author, Benjamin Fiedler, a senior at Cornell University who has been accepted as a first-year medical student at the Schmidt College of Medicine; Lawrence Fiedler, M.D., a gastroenterologist and affiliate associate professor; Michael DeDonno, Ph.D., assistant professor; Kosi Anago, M.D., a former internal medicine resident; Leonie de la Cruz, a former medical student; and George R. Luck, M.D., associate professor, all in FAU’s Schmidt College of Medicine.
“These data pose major challenges that require multifactorial approaches by clinicians and their patients,” said Benjamin Fiedler. “These approaches should include therapeutic lifestyle changes, adjunctive drug therapies as well as screening.”
Therapeutic lifestyle changes of proven benefit include avoiding and treating overweight and obesity as well as regular physical activity and adjunctive drug therapies including aspirin.
“By utilizing these multifactorial approaches, we believe that these efforts should achieve the most good for the most patients concerning the prevention as well as screening and early diagnosis and treatment of colorectal cancers,” said Hennekens, who has done ground-breaking research on the benefits of statins, aspirin, angiotensin converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs) as well as beta adrenergic blockers — all of which play major roles in decreasing premature deaths from heart attacks and strokes.
Hennekens was the first to demonstrate that aspirin significantly reduces a first heart attack as well as recurrent heart attacks, strokes, and cardiovascular death when given within 24 hours after onset of symptoms of a heart attack as well as to a wide variety of patients who have survived a blockage in the heart, brain or legs. His landmark and first discoveries on aspirin are not limited to cardiovascular disease and include the prevention of recurrent migraine headaches. He also hypothesized from earlier observational study data that aspirin may decrease risks of colorectal cancer and delay cognitive loss as well as reduce the development of type 2 diabetes. Since then, randomized trials and their meta-analyses have indicated that aspirin prevents colorectal polyps as well as colorectal cancer.
“More than 90 percent of patients diagnosed with colorectal cancer are 50 years or older. The major risk factors are similar to those for heart attacks and stroke and include overweight, obesity as well as physical inactivity, a diet low in fiber and high in fat as well as type 2 diabetes,” said Lawrence Fiedler, M.D.
According to the U.S. Centers for Disease Control and Prevention, additional risk factors include inflammatory bowel disease such as Crohn’s disease or ulcerative colitis; a personal or family history of colorectal cancer or colorectal polyps; and a genetic syndrome such as familial adenomatous polyposis or hereditary non-polyposis colorectal cancer (Lynch syndrome).


Dimetix C series laser distance sensors are ideal for non-contact distance measurement at both short and long ranges. The lasers measure as close as 0.05 m (2 inch) and as far as 500 m (1,640 feet) with accuracies up to 1.0 mm and a resolution of 0.10 mm.
The laser range finder can be used independently to measure distance, level, position, and to detect movement. Pair of lasers can be mounted to measure thickness, length, and diameter. Dimetix long range laser sensors are ideal for both in process dynamic and static measurements.
Dimetix laser sensors are built tough with a solid aluminum IP65 rated housing. Many of our customers place the laser sensors on the factory floor under typical production conditions, so their ruggedness is proven. The lasers are also used outdoors in extreme conditions.
- FLS-C for the fastest and most accurate measurements over the longest distance
- DLS-C for millimeter accuracy over 150 m
- EDS-C for economical mm accuracy over 30 m in a compact package
The Dimetix C series long range laser sensors are extremely versatile. We have placed the long range laser distance sensor in a wide variety of measurement applications:
- Roll diameter and length
- Crane / gantry location
- Saw cut length monitoring
- Level monitoring in mining operations
- Web width
- Bar length and location
Dimetix DLS-C and FLS-C laser distance sensors include serial and analog outputs with digital inputs and outputs available for alarming and triggering. The serial interface permits simple remote monitoring using an optional panel display.


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Top rated Family Law attorney in Alexandria, MinnesotaMcCarten Law Firm Ltd
Practice Areas: Family Law, Criminal Defense, Estate Planning & Probate view more
Licensed in Minnesota since: 2011
Education: Willamette University College of Law
McCarten Law Firm Ltd123 3rd Ave E
Alexandria, MN 56308
Andrew Wiener is a top-rated attorney practicing in the Alexandria, Minnesota area. Providing legal representation in Minnesota for a variety of different issues, Andrew Wiener was selected to Rising Stars for 2021 - 2023. He is admitted to practice before the courts in Minnesota.
After completing undergraduate studies, Andrew Wiener attended law school. Andrew Wiener was enrolled at Willamette University College of Law. He earned a juris doctor degree in 2011. Andrew Wiener was admitted to the practice of law in 2011.
Attorneys like Andrew Wiener are recognized by their peers for their outstanding work and commitment to the spirit of the legal profession. Their knowledge of the law, professional work ethic, and advocacy on behalf of their clients allow them to stand out among other attorneys in the field.
Andrew Wiener represents clients with Family Law issues. Additional legal issues represented include Criminal Defense, Estate Planning & Probate and Personal Injury - General: Plaintiff.
Practice areasFamily Law, Criminal Defense, Estate Planning & Probate, Personal Injury - General: Plaintiff
Attorney resources for Andrew Wiener
Additional lawyers you may be interested in
Family LawMargaux C. Soeffker, LLC
Family LawDeWitt LLP
Family Lawde Beer & Associates, P.A.
Family LawM. Sue Wilson Law Offices, PA
Family LawBowden Cyr PLLC

domain: law


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Rally road closures
There will be road closures and changed traffic conditions throughout the Coffs Coast this weekend as Round 10 of the World Rally Championships revs up.
Harbour Drive in central Coffs Harbour will be closed until 6am Monday morning 16 September, 2013.
Brelsford Park, Coffs Harbour will be the Rally Hub where preparations will take place as well as the nightly Super Special Stage and teams' Service Park.
The Pacific Highway north and south of the city will be managed and monitored closely as rally spectators and through-traffic merge during the rally.
Road closures in the area include:
Harbour Dr, between Earl St and North St-Wed 7pm to Mon 6am
Earl St, between Harbour Dr and Albany St-Wed 7pm to Mon 6am
Park Ave, between Earl St and Gordon St-Wed 7pm to Mon 6am
Curacoa, between Albany St and Harbour Dr-Wed 6am to Mon 6am
Check the NSW live traffic website before you head to the rally.


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Everybody is by now familiar with the topic of net neutrality. This is the question of whether the owners of high-speed transmission networks for internet traffic have the right to regulate the flow of data, assigning some information to what is in effect the slow lane while allowing other content to barrel ahead in express.
This issue still hasn’t been fully dealt with. As I posted in April, the FCC ordered Comcast to stop interfering with traffic through BitTorrent, a peer-to-peer file-sharing service that the ISP claimed was using up too much bandwidth. Comcast sued, on grounds that the FCC didn’t have the authority to issue it such an order–and won.
The FCC responded by moving to reclassify Comcast as a public utility, like phone companies ATT or Verizon, so that it would have the regulatory authority it needed. This opens a whole political can of worms, however, so it’s still not clear where matters stand.
GOOG’s ITA purchase
The wheel of competition has recently taken a turn in a different, but related, direction with Google’s agreement to buy ITA Software, founded by MIT scientists and now held by private equity, for $700 million. ITA makes the airline database search software that powers the air part of travel sites for online agencies like Kayak and Orbitz, as well as for the online sales sites of Continental Air.
GOOG’s isn’t the first purchase of this type. Two years ago, MSFT paid $115 million for the smaller private company Farecast, which is at the heart of MSFT’s Bing Travel service. But ITA is bigger and already services significant third-party customers.
Not everyone is happy with this development–especially not Barry Diller, CEO of online travel agent (and former MSFT subsidiary) Expedia. He’s worried that if/when it acquires ITA, GOOG will promote its own services over those of EXPE.
This assumes, of course, that GOOG will follow MSFT’s lead and create a travel site similar to Bing Travel. That may well happen. In paid search, a prospective GOOG Travel could outbid everyone else for keywords, since this would just be transferring revenue from one GOOG pocket (travel) to another (search). It’s not so clear that would happen in any unfair manner in unpaid search. The reputational, and legal, risk to GOOG is too high, I think, for that to occur.
EXPE isn’t out of the woods by any means, however–in my opinion. It’s possible that the combination of GOOG and ITA professionals will produce new travel software that’s significantly better than anything on the market today. Maybe ITA can do this alone, with GOOG financial support.
Suppose that instead of using ITA software itself GOOG offers it for free to any travel site that is willing to allow GOOG advertising on it. This is basically what it did with cellphone operating system software. That would give any takers a 10%-15% cost advantage over sites which either develop their own travel software or buy it from third parties. It would also make it easier for new firms to enter the market. Any way you look at is, GOOG offering ITA for free would lower the value of any database technology that a company like EXPE holds.
That’s Mr. Diller’s real problem, I think. If so, he can’t just say this–that there’s something wrong with a new market entrant turning up with better, lower-cost technology. Search neutrality may be the best weapon he has to fight with.


Binder M12 Food & Beverage Series
Compact circular connector system with industry standard IEC 61076-2-101 M12x1 screw locking interface.
M12 Food & Beverage connectors offer pin-counts of 3 to 12 with a current carrying capacity of up to 4A per contact.
The series caters for cable OD’s of up to 6.5mm, has a wire gauge max. of 0.75mm² and is capable of offering IP67, IP68 & IP69K ingress protection in mated state or with the use of a protection cover.
Robust and compact circular connectors from one of the industry’s most trusted brands
The new Binder M12 connector programme is specially designed to fulfil the requirements of the food & beverage industry. All products are both IP69K and Ecolab (ECL) tested.
In addition, 1.4404 stainless steel and special plastics is used to ensure corrosion resistance, making these products ideally suited for packaging, processing and filling facilities for foods & beverage.
The range comprises of a variety of straight and angled male and female field wireables, panel receptacles with pre-terminated wires and moulded cable connectors with heads made from cream-coloured RAL 9001 polypropylene plastic.
The connectors are available in 3, 4, 5, 8 & 12-pole versions in accordance with DIN EN 61076-2-101 and DIN EN 61076-2-104 respectively. Maximum current is 4A at 250V.
As well as the food & beverage sector, these new M12 circular connectors are suitable for use in the pharmaceutical and chemical industries and in other types of industrial food processing, including milk and cheese dairies, abattoirs, bottling plants and food storage. These are all areas where stringent hygiene requirements have to be met for machinery, systems and components.
binder have designed these M12 connectors using premium materials including stainless steel and special plastics with highly smooth contours to prevent dirt adhesion. Because high pressure cleaning with aggressive chemicals is widely used throughout these food and beverage sectors, these M12 connectors provide protection to IP68 and IP69K.
These versions look different from standard M12 connectors while the light-coloured surface means dirt and residue are easy to spot. In addition to the existing tests and the UL certification that is under preparation, the connectors have been subjected to the Ecolab test seal that confirms the material’s resistance to detergents and disinfectant.
For a more detailed description of this connector series please see the manufacturer's brochure which is available to download above.
For a personalised quotation on any of the part numbers seen in this range please complete the 'Quick Quote' form or simply call us on 01744 815001.


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Phthalates, man-made chemicals used in a variety of products, may have endocrine-disruptive effects in reproductive-age women, increasing or decreasing their risk of endometriosis, according to a new study by the University of Washington School of Public Health. Researchers found that a majority of the 287 women they studied through an integrated healthcare delivery system in Washington state had detectable concentrations of phthalate metabolites in their urine. Phthalates are used to soften and add flexibility to plastics or as solvents or fixatives.
The study, published in the journal Environmental Research, found that one metabolite of di(2-ethylhexyl) phthalate (DEHP) was linked to a strong decreased risk of endometriosis, a condition where the lining of the uterus grows outside the organ, often resulting in chronic pelvic pain and infertility.
“We were not surprised with this result as prior animal laboratory studies have demonstrated that DEHP is toxic to ovaries and reduces the production of hormones, including estrogen,” said lead author Dr. Kristen Upson, who earned a PhD in epidemiology earlier this year from the University of Washington. “Because endometriosis is an estrogen-driven disease, it makes sense that a chemical that reduces estrogen production may reduce the risk of endometriosis.”
Researchers observed that different phthalates may alter the risk of endometriosis in different ways. For example, the metabolites of two phthalates studied may be associated with increased risk of the disease. Little is known in this area, despite the majority of women being exposed to phthalates. Further research is needed to confirm their findings and to understand the biological mechanism of how phthalates may alter disease risk.
The research was supported by funding from the Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institute of Nursing Research, Environmental Protection Agency, and University of Washington School of Public Health department of epidemiology.
To read more, click here.
[Photo: Dr. Kristen Upson]


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Though his reps would neither confirm nor deny it, the Age of Aquarius-minded singer is reportedly taking on the role of Jimi Hendrix in an upcoming biopic. Electric Lennyland, here we come!
Posted December 9 2005 — 12:00 AM EST
- 'Sports Illustrated' reveals how the NFL persuaded Michael Jackson to perform at the Super Bowl
- Rachael Taylor joins 'A.K.A. Jessica Jones'
- Study: Binge-watching TV might make you sad
- A.J. McLean previews 'raw' Backstreet Boys documentary
- NEEDTOBREATHE teams with Gavin DeGraw for 'Brother'
- Disney to intro its first Latina princess
- Box office preview: 'Project Almanac' joins 'American Sniper' in theaters

domain: celebrity


More people are dying in fewer accidents
Increase first since 2005
In 2011 Missouri saw a slight decrease in the number of motocycle accidents in the first 9 months.
The first significant snowfall of the season couldn’t have come at a worst time.
Heavier-than-expected snow greets Monday morning commuters.
ST. LOUIS, Mo. (KMOX)- The freezing drizzle that moved across the region Wednesday evening left behind slick streets and sidewalks, leading to several accidents and a few falls.


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Celebrations and weddings
We offer you an ambience full of atmosphere and we organize your event.
Our bright rooms are ideal for weddings, birthday parties, religious celebrations or events with your company. Our four special rooms and the terrace provide enough space for 150 guests.
Our hotel staff that speak German, English and Czech will welcome you and prepare menus, buffet cards and organize a wine presentation for you.
Your guests can spend the nights in one of our 33 cosy rooms with a great view.
Public room - up to 50 guests
It’s a very comfortable room with a large bar and a wooden grape press. In this room you can choose your own table arrangements.
Our restaurant - up to 60 guests
In our restaurant you will have a great view at the wineyards and the Church of Poysdorf. Here you can dine stylishly with your family or your business partners.
Room “Steinbergen“ - up to 32 guests
It’s the ideal room for small groups to celebrate baptisms, confirmations, birthdays or events with your business partners.
Room “Sommertal“ - up to 60 guests
If you want to invite your big family and if your children want to play in our kid’s corner, then please book this room.
You may connect all rooms – so this is ideal for big celebrations:
- Restaurant and Steinbergen – up to 60 guests
- Steinbergen and Sommertal – up to 90 guests
- Restaurant, Steinbergen and Sommertal – up to 150 guests
- a combination of all rooms – up to 200 guests


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The dipeptidyl peptidase-4 (DPP-4) inhibitor saxagliptin in combination with metformin has been suggested to significantly improve glycaemic control compared to either monotherapy in type 2 diabetes (T2D). In addition, metformin and other DPP-4 inhibitors have been shown to protect against ischemic injury in clinical and experimental studies. We therefore hypothesised that chronic treatment with saxagliptin monotherapy may protect the T2D heart against myocardial infarction. Moreover, in combination with metformin, an enhanced effect may be achieved. Goto-Kakizaki (GK-a model of T2D) rats received, via oral gavage, either saxagliptin (30 mg/kg/day), metformin (300 mg/kg/day),metformin & saxagliptin (300 mg/kg/day & 30 mg/kg/day) or vehicle (water) for 2 weeks. Blood glucose was measured before and throughout the treatment. Rats were subjected in vivo to 30min ischaemia/120min reperfusion. The infarct was quantified using TTC staining and expressed as a percentage of the myocardium at risk (I/R%). Both saxagliptin and metformin alone reduced myocardial infarct size (I/R%: 24.7 ± 1.4% with saxagliptin, 18.7 ± 2.5% with metformin, versus 44.6 ± 2.2% with vehicle; P < 0.05: N ≥ 6/group). However, no additive protection was observed when the two agents were co-administered (I/R%: 28.1 ± 3.2% with saxagliptin/metformin combination vs 44.8 ± 4.0% with vehicle). Interestingly, neither treatment (monotherapies/combination therapy) reduced blood glucose significantly following the 2-week treatment. (Before and after treatment, blood glucose in mmol/L: saxagliptin, 9.1 ± 0.5 to 8.3 ± 0.7, metformin, 9.4 ± 1.0 to 8.2 ± 0.3 and combination, 10.7 ± 0.3 to 7.6 ± 0.4). This study highlights the infarct-limiting effect of chronic saxagliptin treatment. The data also suggest that the cardioprotective mechanism of saxagliptin may be similar to that of metformin as these drugs did not manifest additive protection when co-administered. Interestingly, the infarct-limiting effects of these agents seem to be independent of their glucose-lowering properties.
Statistics from Altmetric.com
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.


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16 Gluten-free Thanksgiving recipes that your guests will love! Including gluten-free side dishes and desserts for everyone to enjoy.
See how I made these DIY Thanksgiving Napkin Rings with nameplates. It’s so easy to add a pop of color to any tablescape with this upcycle!
Get inspired by this tutorial that transfers pickle jars into spooky decor and learn how to make Upcycled Halloween Jars using the Cricut.
Get dad the gifts he actually deserves this year. This Father’s Day Gift Guide is full of unique ideas for gifts that dad is going to love.
For those of us that waited until the last minute to pick up a Mother’s Day Gift, these ideas are so good, she won’t mind it being late.
Are you still looking for that perfect gift? Check out my suggestions on the best Christmas presents to get for everyone on your list.
Learn how to upcycled an old wreath & create this DIY Halloween Wreath in just a few minutes using random supplies you may already have in your home.
This Christmas Craft is made using wrapping paper scraps and the left over tube creating a set of DIY Poinsettia Napkin Rings.
These DIY Christmas Gifts make perfect presents for everyone on your list. Handmade gifts that come from the heart that your family and friends will love.
This beauty gift basket idea is sure to please any makeup lover. Packed with products created to help express a supercharged personality and accentuate natural beauty.

domain: artistic


Enjoy a Unicorn Single Duvet Cover for the child’s room. Featuring a soft pink and white color, as well as a flower emoji, this stunning twin single bed duvet cover will make a wonderful bedroom decor.
- Material: 100% Cotton Polyester
- Digital HD printing
- Soft and silky material
- 🚚 Free Delivery
- Shipped in 24 48h


Jupiter is one of the most stunning objects in the night sky, and while it is relatively close to us are far as objects in space go, it is still a mind-bogglingly far distance from our home planet, making it a real challenge to photograph. This neat video goes behind the scenes to show the process an astrophotographer went through to get a photo of the biggest planet.
Coming to you from Astro Backyard, this fascinating video shows the process of taking an image of Jupiter. Jupiter was recently in opposition with Earth (meaning our planet had passed between it and the sun) and was near its closest distance to our planet, which made it especially large and bright in the night sky, ideal for photographing it. But even at its closest, it is still about 600 million km (373 million miles away), a distance that is hard to fathom and that makes it a real challenge to image. In fact, for this shot, it took 10,000 frames taken through a Celestron Edge HD 11 telescope with a planetary imaging camera, from which the best 3,000 frames were selected and combined to create a single final photo! It is certainly a ton of work, but seeing the result must be tremendously satisfying. Check out the video above to see what it took.


[Video] 2013 K-Pop Group Debuts
With K-Pop going as strong as ever, the endless wave of new group debuts continues to keep us entertained.
These two videos feature debuts from 36 boy groups and 31 girl groups! (that is 163 boys and 121 girls!) This is a little less than last year, which had 38 new boy groups and 41 girl groups. In trying to cover as much as possible, vocal groups, duos, bands, rappers, and sub units are included.
The groups are featured in order of debut.
To allow for more variety, it seems companies have further embraced the idea of sub units. This year we had Infinite-H, ZE:A5, uBEAT, 100% V, 2YOON, DASONI, T-ara N4, M&N and BOM&HI.
Another interesting thing to note this year is that there wasn’t there wasn’t a debut from the big 3 (not counting sub units). However, they do all have plans for new groups in 2014. YG‘s Winner, while on TV has yet to make their official debut. JYP will be releasing their new boy group GOT7 this month, along with another boy group and girl group later. SM has just started showing off their trainees through SM Rookies.
While it would be nearly impossible to copy the level of popularity EXO and B.A.P in their 2012 rookie year, there are definitely a few standouts from last year.
Who do you think were the strongest debuts of 2013?
While NOM made their debut with a cute song, there is actually another group out there named N.O.M which features male erotic dancers.
Alphabat and QUEEN B’Z are re-debuts. The members of Duo Flo are from former girl group Six Bomb. Three of the members of BESTie are former EXID members.


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“I think when I met you, I became myself. We stumbled toward this mad world and made sense of it. Together.”
It would be hard to imagine Bethany and Jonathan without one another… They are so perfectly suited for one another, loving the same things like 4 wheeling and chasing waterfalls!
When I first met Bethany and Jonathan, their connection to each other and to nature was so obvious. They requested to have their Engagement Photos done at a Waterfall, because they had managed to visit most of the waterfalls in the province, and wanted to check another one off the list! Definitely my kind of folks! You can see there Engagement Photos here.
Bethany’s wedding day started with Mimosas and hair of course!. Bethany, along with her Maid of Honor and Mom, Aunt and Gr. Mom, gathered to have a little pampering. From there they met at the house where she grew up. A house that holds so many special memories for her. Bethany’s mom helped her with her finishing touches, so they could get to the wedding site on time!
They chose to have the ceremony overlooking the Hartland Covered Bridge, which just happens to be the longest covered bridge in the world! It’s also where they grew up, and it’s a place that’s so familiar to them.
Bethany and Jonathan, surrounded by loved ones, and with the sound of the mighty St. John River in the background, pledged their love for one another and I couldn’t imagine a better day for it.
Here is a little peak into their day.
Venue : Hartland Covered Bridge Park
Special thanks to the following vendors for making this day so special.
Hair: Hairraiser 678
Makeup: Hairraiser 678, Callie Anderson
Nails: Amykins Nail Art, Amy King
Suits: Tip Top Tailors
Gown: Opportunity Bridal
Alterations: Lil’s Alterations
Flowers: Greenhouse Window
Cake: Emily Gormley
Reception Decor: Debbie Taylor
Officiant: Suzette MacDonald


Marine Integrated Autonomous Observing Systems
The UK must fulfil statutory obligations for monitoring the state of the sea. This means we need to collect data that enable assessment of the status of marine ecosystems and effective management of Marine Protected Areas (MPAs). Autonomous technologies could make marine observation more cost-effective, while accelerating our understanding of marine ecosystem function and its response to climate change and other pressures.
This research programme is co-funded by NERC, the Department for Environment & Rural Affairs (Defra) and WWF-UK. It will address the scientific and technical challenges of using new technologies to deliver a more efficient and integrated next-generation UK marine observing programme, capable of meeting science and policy data requirements now and into the future.
The overarching objective is to accelerate the use of autonomous measurements and combined observational-model outputs in meeting long-term science need and statutory policy requirements.
17 Oct 2017
The MIAOS moderating panel will consider applications made to the call that closed on 28 June 2017, and meet on Tuesday 24 October 2017.
New and emerging marine technologies (autonomous platforms, miniaturised sensors, and remote or automated data collection methods) provide opportunities to transform the temporal and spatial coverage of marine observations for both scientific and monitoring purposes. Over recent years the research councils, higher education institutions and industry have invested over £100 million in smart and autonomous observing systems.
Marine autonomous vehicles are now routinely deployed to support NERC science, and are increasingly demonstrating their capability for complex multiple deployments with novel sensors - external link, making high-quality targeted observations to improve our scientific understanding of nutrient and carbon cycling within the shelf seas. These technologies offer the potential to observe the marine environment cost-effectively over large areas and long periods of time.
The UK must fulfil statutory obligations for monitoring the state of the seas, eg as demanded by the Marine Strategy Framework Directive (MSFD) - external link, the Convention on Biological Diversity - external link and the OSPAR Convention - external link. This means we need to collect data that enable assessment of the status of marine ecosystems and the effective management of Marine Protected Areas (MPAs). Autonomous technologies could make marine observation more cost-effective, while accelerating our understanding of marine ecosystem function and its response to climate change and other pressures. To achieve these benefits, more research is needed to prove how their capabilities can be used and integrated with existing techniques.
Marine ecosystem services were valued at $50 trillion in 2011. It is thought that over two-thirds of the overall economic value of the ocean depends directly on healthy ocean conditions. Model studies reported in the most recent Assessment Report of the Intergovernmental Panel on Climate Change (IPCC) predict damage to marine ecosystems and cascading consequences to human populations that rely on ocean productivity.
It is crucial, then, that we develop a more complete understanding of the marine ecosystem response to natural and anthropogenic variability. This will allow us to develop better management strategies for human impacts on the marine ecosystem. Understanding the oceans' long-term resilience to climate change, so that mankind can sustain and increase ecosystem benefits, is a high-level priority of the UK Marine Science strategy.
Integrating new technologies with existing marine observing infrastructure and data archives is a significant challenge. This programme will build on previous and planned NERC and co-funded projects (eg Shelf Seas Biogeochemistry and Marine Ecosystem Research programmes) to advance our understanding of marine ecosystem function. Bringing observations from multiple sources together with models more effectively is essential to assess how different stressors (natural or anthropogenic) can affect diverse habitats over various timescales, and what impact these have upon ecosystem services.
- WWF report - Reviving the ocean economy summary (PDF) - external link
- Mora C, Wei C-L, Rollo A, Amaro T, Baco AR, et al. (2013) 'Biotic and Human Vulnerability to Projected Changes in Ocean Biogeochemistry over the 21st Century'. PLoS Biology 11(10): e1001682. doi:10.1371/journal.pbio.1001682 .
- IPCC, 2014: Summary for policymakers. In: Climate Change 2014: Impacts, Adaptation, and Vulnerability. Part A: Global and Sectoral Aspects. Contribution of Working Group II to the Fifth Assessment Report of the Intergovernmental Panel on Climate Change- external link [Field, C.B., V.R. Barros, D.J. Dokken, K.J. Mach, M.D. Mastrandrea, T.E. Bilir, M. Chatterjee, K.L. Ebi, Y.O. Estrada, R.C. Genova, B. Girma, E.S. Kissel, A.N. Levy, S. MacCracken, P.R. Mastrandrea, and L.L. White (eds.)]. Cambridge University Press, Cambridge, United Kingdom and New York, NY, USA, pp. 1-32.
- UK Marine Science strategy (PDF) - external link
2016 - 2021
Can I apply for a grant?
Opportunities will be listed on the News page when available.
This programme has a budget of £3·6 million.


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17th of November is a very important holiday for Czechs and Slovaks, because it is the Struggle for Freedom and Democracy Day. The day when thousands of students went to the streets to protest against the Russian occupancy of the one-party government of the Communist Party of Czechoslovakia, starting a non-violent nation-wide protests, the "Velvet Revolution".
However, a staggering amount of young people don't know or don't care about this date and with O2 we've tried to reach its awareness into the public with previous year's campaign, creating a digital iron curtain. On the next year we had decided to continue in this effort with O2 again.
We let the young live through the Velvet Revolution as a first-hand experience, as if it happened in the year 2017. We've launched a Facebook livestream from the past that has started at the exact same time as the protests started in the 1989 and ran it for 3 hours, broadcasting authentic archive videos from the protests, full of shouts for freedom. The video was supported by Insta-stories that looked exactly the way they would look like if the revolution was happening today.
Watch the campaign recap in this case study.
13%increase of fairness brand attribute — the most relevant attribute in telco market
The 2016/2017 campaign activities have won 2 shortlists in Cannes Lions creative festival, and gold and silver trophies in Euro Effie 2018, making it the most successful campaign in Slovak history.
Fun fact: the person narrating the case study is an Englishman originally from Latvia and he offered to narrate the study for us because topic is especially personal for him, since it reminded him of why he had to leave his home country when he was young.


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Duration: 7/8 hours
Every year Monterosso, Vernazza, Corniglia, Manarola and Riomaggiore attract tourists from around the world. No one is disappointed by the charm of Cinque Terre, one of the most uncontaminated Mediterranean areas in Liguria, characterised by unspoiled nature and a landscape that has remained unchanged over the centuries.
We will accompany you to the five seaside villages, now a UNESCO heritage site. Here you can experience the unique emotion of being suspended between the vibrant vegetation of the Mediterranean hills and the deep blue sea, where you can gaze off into the distance and let your thoughts run free. You will discover how the determined and stubborn locals have affectionately shaped the harsh terrain for centuries, living off the land without ruining its extraordinary beauty.
We will tell you anecdotes and stories that reveal the natural and architectural treasures of Cinque Terre: a place where colours, fragrances, sounds and flavours form unique and unrepeatable symphonies.


The man who died Wednesday night after being tased during an altercation with deputies had no criminal history in Etowah County, authorities say.
Christopher Shane McKinney, 39, was pronounced dead at a local hospital, Sheriff Todd Entrekin said, where he’d been taken for treatment after he appeared to stop breathing after he was tased by deputies and members of the county’s Special Operations Detail.
ECSO Director of Communications Natalie Barton said McKinney’s body has been sent to the state forensic lab for an autopsy, which may take some time.
The events that preceded McKinney’s death began just before 5 p.m. Wednesday, when a woman came into the sheriff’s office on Forrest Avenue, reporting that a man was causing a disturbance in the parking lot and harassing people.
Two deputies found the man as he was about to enter the sheriff’s office and began to speak with him.
“They tried to talk to him,” Entrekin said. “He started pushing, and being belligerent.” Then it turned into a fight, he said.
The altercation that began in the vestibule area at the front of the ECSO moved outside.
“The dispatcher saw it and called for the SOD team,” Entrekin said, and the deputies called for help as well.
The man was tased multiple times, the sheriff said, and deputies were able to subdue him. He was cuffed and on the ground and appeared to be all right.
“We called the medics,” Entrekin said. “We always call the medics when we tase someone.”
Entrekin said as he understood it, medics arrived, then McKinney stopped breathing. CPR was performed and he was rushed to a local hospital, but did not survive.
Hours after the incident, members of McKinney’s family came to the ECSO, having apparently heard something occurred there involving McKinney.
A distraught woman asked to see her brother, and asked what happened. Entrekin, Chief Deputy Michael Barton and District Attorney Jody Willoughby were present, and they urged her and the man accompanying her to come inside so they could talk to them.
“Where is he? I need to see him,” the woman said, repeatedly.
Entrekin told her McKinney had been taken to the hospital, that he was then being taken to the morgue and the woman knelt, crying, in front of the sheriff’s office.
“I tried to get him help,” she said. She told them she’d talked to him earlier in the day.
Entrekin said the man apparently had been hanging around in the area of the sheriff’s office for a few days before the incident Wednesday, and deputies had some contact with him in the preceding days.
The sheriff said all evidence in the case has been turned over to the Oxford Police Department — investigating the case because Etowah law enforcement officers were involved. That evidence includes body camera footage from the officers.


Will the Big Bike-Share Supplier's Bankruptcy Hurt the Program in U.S. Cities?
The Canadian company that is the main equipment and technology suppliers for bike-sharing systems across the U.S. has filed for bankruptcy.
Public Bike System Co., (PBSC) which owns the widely used BIXI bike-sharing system, announced the bankruptcy Monday, citing almost $50 million in debt, as first reported by the Montreal Gazette. Its bikes and technology are used in 16 areas around the world, including major cities such as Chicago, New York, London, Montreal, and Washington, D.C.
After the bankruptcy was announced, Alta, a company that operates several BIXI bike-share systems in the U.S., said in a statement that its customers won't have their service interrupted. Alta says it plans to expand current systems and launch new ones this year.
PBSC's bankruptcy doesn't jeopardize bike-sharing, says Elly Blue, author of Bikenomics, a book analyzing the economics of cycling.
"I don't see this as being a very big bump in the road for bike share," Blue says. "I just see this as a chance for cities to learn — we can't run our transportation systems like a business, it doesn't really work that way because then we run the risk of not serving the people that need to be served."
PBSC attributes the bankruptcy partly to cities that have not paid it, including around $5.1 million from New York and Chicago. It is also in a lawsuit with the company that makes its bike-share analysis software.
The bankruptcy doesn't surprise John Pucher, who studies bicycling as a professor of urban planning at Rutgers University and who recently published a book about the cycling boom in cities.
"Looking at the operating data of the cost and revenues of the [bike-sharing] systems that I've seen, they vary from one system to another, but I'm just not convinced overall that it's a profitable venture," Pucher says. "It's not a big money maker the way they've set it up."


Are you looking to achieve a flawless, glossy finish for your automotive project? Spray Max 2K Clear Glamour is your go-to solution for professional-grade clear coating. With its advanced formula, this automotive clear coat delivers exceptional results, providing a durable and high-gloss finish that enhances the appearance of your vehicle. In this guide, we’ll walk you through the steps to achieve a stunning finish using Spray Max 2K Clear Glamour.
Step 1: Preparation
Before you begin the clear coating process, it’s crucial to prepare the surface properly. Follow these steps:
- Clean the surface: Start by thoroughly cleaning the surface you’ll be coating. Remove any dirt, grease, or contaminants using a high-quality automotive cleaner.
- Sanding: If necessary, use sandpaper to smooth out any imperfections or rough spots on the surface. This step ensures proper adhesion of the clear coat.
- Masking: Protect any areas that you don’t want to coat with clear by using masking tape and plastic sheets. This will prevent overspray and ensure a clean finish.
Step 2: Mixing the Clear Coat
Spray Max 2K Clear Glamour comes in a two-component aerosol can, consisting of the clear coat and a hardener. To achieve optimal results, follow these instructions:
- Shake the can: Prior to use, shake the aerosol can vigorously for at least two minutes to ensure proper mixing of the components.
- Attach the activator: Remove the red button from the cap and attach it to the bottom of the aerosol can, which will release the hardener into the clear coat when activated.
- Activate the hardener: Press the red button firmly to puncture the seal, allowing the hardener to mix with the clear coat. Shake the can again for another two minutes.
Step 3: Applying the Clear Coat
Now that you have your clear coat mixture ready, it’s time to apply it to the surface:
- Test spray: Before applying the clear coat to the entire surface, perform a test spray on a separate surface or inconspicuous area to ensure proper atomization and to get a feel for the spray pattern.
- First coat: Hold the can approximately 6-8 inches away from the surface and apply a light, even coat of the clear coat in a sweeping motion. Overlap each pass slightly for consistent coverage.
- Flash-off time: Allow the first coat to flash off for the recommended time specified on the product label. This will vary depending on environmental conditions and the specific clear coat you’re using.
- Additional coats: Apply subsequent coats following the same technique, allowing proper flash-off time between each coat. Usually, 2-3 coats are recommended for a glossy and durable finish.
Step 4: Final Touches
Once you’ve applied the desired number of clear coat layers, follow these final steps for a professional finish:
- Cure time: Allow the clear coat to cure fully as per the manufacturer’s instructions. This typically involves letting the coated surface dry for a specific duration to achieve maximum hardness and durability.
- Buffing and polishing: If necessary, after the clear coat has cured, you can use polishing compounds and a buffing pad to remove any imperfections and further enhance the glossiness of the finish.
With these steps, you can achieve a stunning finish using Spray Max 2K Clear Glamour. Remember to follow safety precautions and work in a well-ventilated area. Enjoy the transformative power of this professional-grade clear coat and give your automotive projects the glossy and flawless look they deserve.
Now, let’s get started on your next automotive masterpiece!


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MaineHealth provides services for the diagnosis and treatment of pancreas cancer. This cancer is a relatively rare, occurring in about 50,000 patients every year in the United States. Approximately 40,000 patients will die of this disease, making it the 10th most common cause of cancer death.
Evaluation by an expert multidisciplinary team can ensure patients receive optimal treatment.
What is pancreas cancer?
The pancreas is an organ about 6-9 inches long between your stomach and spine. The pancreas makes hormones (such as insulin) and digestive enzymes. The most common pancreatic cancer is adenocarcinoma. Pancreas cancer occurs when the normal cells begin to grow uncontrollably. Pancreatic cancer is aggressive, often invading adjacent organs and it spreads early.
Risk factors for pancreatic cancer
Patients diagnosed with pancreatic cancer often have no significant risk factors. Researchers have found that certain risk factors to be associated with a higher likelihood of this disease. These risk factors include a close relative with pancreas cancer or and inherited cancer syndrome, smoking, diabetes, inflammation of the pancreas (pancreatitis), a diet high in fats, and obesity.
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Pancreas cancer symptoms
Early cancers of the pancreas are often asymptomatic. Many patients will present with subtle symptoms that worsen over time. Common symptoms include jaundice or yellowing of the skin, upper abdominal pain that goes to the back, nausea, vomiting, dark urine, and light-colored stools that float in the toilet. As cancer progresses, patients may note weakness, fatigue, and weight loss.
Pancreas cancer diagnosis
The diagnosis of pancreatic cancer can be difficult. Initial testing often involves CT, MRI, PET, and ultrasound scans. Advanced endoscopic procedures can help with diagnosis and treatment of pancreatic cancer.
- ERCP is a procedure where a gastroenterologist passes a lighted scope into the first part of your intestine to the bile and pancreatic ducts.
- Endoscopic ultrasound involves the gastroenterologist using a similar lighted scope with a special ultrasound tip that can visualize the pancreas.
The gastroenterologist can use these techniques to perform a biopsy.
Pancreas cancer treatment
Treatment options for patients with pancreatic cancer include surgery, chemotherapy, targeted therapy, and radiation therapy. Often patients will be given the combination of these treatments. Surgery is the only curative therapy for pancreatic cancer. Unfortunately, at the time of diagnosis, a minority of patients are candidates for surgery. Preoperative treatment with chemotherapy and radiation can increase the ability to remove tumors
The treatment of pancreatic cancer can be quite challenging for patients and physicians. To ensure optimal treatment, Maine Medical Center has assembled a multidisciplinary team including surgeons, gastroenterologists, medical oncologists, radiation oncologist, pathologist, and interventional radiologist to treat this complex cancer. This team meets regularly to coordinate patient care.
For patients who are not candidates for surgery, life can be extended and symptoms improved by treating with chemotherapy, targeted agents, and radiation.
Given the complex treatment options for patients with the adenocarcinoma of the pancreas, patients may benefit from multidisciplinary management by the team at MaineHealth and Maine Medical Center.


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In honor of National Rural Day on November 16, McKenzie Health System invited local schools to tour the McKenzie Hospital Campus and participate in entertaining and educational activities to build awareness about the healthcare needs of rural communities and inspire interest in healthcare careers. The National Organization of State Offices of Rural Health (NOSORH) founded National Rural Health Day (NRHD) in 2011 as an opportunity to recognize the “power of rural” by honoring the selfless, community-minded spirit that prevails in rural America. Over the years, NRHD has transformed from a day-long event to a sustainable movement, recognized annually on the third Thursday of November.
The Sherlock Holmes themed tour included fun and informative activities to help students explore the many career options in local healthcare. Students competed in a scavenger hunt to win a pizza party for their school participants. All students won in terms of expanding their understanding of the healthcare field as they think about their future; the school who collectively answered the highest percentage of questions correctly was Sandusky High School at 97.2%. Photos from the tours of each participating school, which included Carsonville-Port Sanilac, Croswell-Lexington, Peck, and Sandusky, are available on McKenzie Health System’s Facebook page.
Rural America is an excellent place for mission-minded health professionals to provide individualized care. McKenzie showcased careers in both medical and non-medical fields that students may want to pursue including providers, nurses, radiologists, phlebotomists, health information management, administration, social work, billing and coding, and human resources.
According to NOSORH findings, “Compared to urban nurse practitioners, rural NPs report being more satisfied with their jobs, fully practicing to the extent of their license, and anticipate staying in their jobs much longer.”
Rural America is fueling an innovative rural health infrastructure that addresses the beautiful yet challenging landscape. NOSORH states that “roughly 1300 Critical Access Hospitals (CAH) and 900 other rural hospitals support rural communities’ acute care landscape,” including McKenzie Health System, just one piece of the rural healthcare puzzle. Along with other rural healthcare providers, State Offices of Rural Health, and rural stakeholders, they deliver unique approaches to address healthcare challenges that rural citizens face today and in the future.
“National Rural Health Day is a special time for McKenzie Health System and our community,” says Billi Jo Hennika, Chief Operating Officer at McKenzie Health System. “We pride ourselves on being an organization focused on reaching for the best way to provide rural healthcare for our patients, and planning for future generations of healthcare workers is part of that focus. Our intention was to inspire local students, and I believe every department who participated in these tours would agree that the students were an inspiration to them.”

domain: health


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It’s natural for anyone trying to lose weight to want to lose it very quickly. But evidence shows that people who lose weight gradually and steadily (about 1 to 2 pounds per week) are more successful at keeping weight off. Healthy weight loss isn’t just about a “diet” or “program”. It’s about an ongoing lifestyle that includes long-term changes in daily eating and exercise habits.
Why? If you have celiac disease and eat gluten, your immune system freaks out a bit. This reaction can mess with the lining of your small intestine, hampering its ability to help you absorb nutrients properly, according to the Mayo Clinic. Inflammatory bowel diseases like Crohn’s disease can also lead to unexplained weight loss due to malabsorption as well.
Sleep enough – for most people at least seven hours per night on average – and keep stress under control. Sleep deprivation and stress hormones raise blood sugar levels, slowing ketosis and weight loss a bit. Plus they might make it harder to stick to a keto diet, and resist temptations. So while handling sleep and stress will not get you into ketosis on it’s own, it’s still worth thinking about.
But people who started following the keto diet noticed weight loss for a few reasons: When you eat carbs, your body retains fluid in order to store carbs for energy (you know, in case it needs it). But when you’re not having much in the carb department, you lose this water weight, says Warren. Also, it's easy to go overboard on carbohydrates—but if you're loading up on fat, it may help curb cravings since it keeps you satisfied.
Variations on the Johns Hopkins protocol are common. The initiation can be performed using outpatient clinics rather than requiring a stay in hospital. Often, no initial fast is used (fasting increases the risk of acidosis, hypoglycaemia, and weight loss). Rather than increasing meal sizes over the three-day initiation, some institutions maintain meal size, but alter the ketogenic ratio from 2:1 to 4:1.
Lose It! This two-week phase is designed to jump-start your weight loss, so you may lose up to 6 to 10 pounds (2.7 to 4.5 kilograms) in a safe and healthy way. In this phase, you focus on lifestyle habits that are associated with weight. You learn how to add five healthy habits, break five unhealthy habits and adopt another five bonus healthy habits. This phase can help you see some quick results — a psychological boost — and start practicing important habits that you'll carry into the next phase of the diet.


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This time, the picture is the story.
After the Secret Service insisted that President Barack Obama was never endangered by a security breach that allowed a couple to crash his first state dinner, the White House has released a photo showing that not only did the pair get close to Obama, they actually shook hands and talked to him.
As the White House was disclosing that the Virginia couple, Michaele and Tareq Salahi, met Obama in the receiving line, a “deeply concerned and embarrassed” Secret Service on Friday acknowledged that its officers never checked whether the two were on the guest list before letting them onto the White House grounds.
The White House released a photo showing the Salahis in the receiving line in the Blue Room with Obama and Indian Prime Minister Manmohan Singh, in whose honor the dinner was held. Obama and reality TV hopeful Michaele Salahi are smiling as she grasps his right hand with both of hers and her husband looks on. Singh is standing to Obama’s left.
The Secret Service earlier this week had said the president was not in danger because the couple — like others at the dinner — had gone through magnetometers. But in light of their close proximity to the president, no such claim was made Friday.
The Salahis were not on the guest list and should have been barred from entering last Tuesday’s dinner on the White House South Lawn for the prime minister of India, said Secret Service Director Mark Sullivan.
Sullivan said the agency that protects the president is “deeply concerned and embarrassed” that procedures were not followed.
“As our investigation continues, appropriate measures have been taken to ensure this is not repeated,” Sullivan said in a written statement.
“The preliminary findings of our internal investigation have determined established protocols were not followed at an initial checkpoint, verifying that two individuals were on the guest list,” Sullivan said. “Although these individuals went through magnetometers and other levels of screening, they should have been prohibited from entering the event entirely. That failing is ours.”
Secret Service spokesman Jim Mackin said officers at the checkpoint had a clipboard with names of the invited guests. Even though the Salahis names weren’t on it, they were allowed to proceed. The officers should have called someone on the White House staff or Secret Service personnel before allowing them past the checkpoint, Mackin said.
Earlier, Mackin said the Secret Service may pursue a criminal investigation of the Salahis.
Sullivan said it wasn’t good enough that his agency screened more than 1.2 million visitors last year to the White House complex and protected more than 10,000 sites for the president, vice president and others.
“Even with these successes, we need to be right 100 percent of the time,” he said.
It is unclear what the couple told officers at the checkpoint that allowed them to go through the security screening. Federal law makes it a crime to knowingly and willfully falsify statements on matters within the federal government’s jurisdiction.
“As this moves closer to a criminal investigation there’s less that we can say,” Mackin said. “We’re not leaving any option off the table at this point.”
White House spokesman Nick Shapiro said the Secret Service will take appropriate action once the review is completed.
“The men and women of the Secret Service put their lives on the line everyday to protect us. They are heroes and they have the full confidence of the president of the United States,” Shapiro said.
The Salahis lawyer, Paul Gardner, posted a comment on their Facebook page saying, “My clients were cleared by the White House, to be there.” He said more information would be forthcoming. Several messages left at Gardner’s law firm on Friday were not returned.
Bravo Media has confirmed that Michaele Salahi is being considered as a participant in the upcoming “The Real Housewives of D.C.” program and on the day of the dinner was being filmed by Half Yard Productions, the producer of the program.
“Half Yard Productions was told by Michaele and Tareq Salahi that they had been invited to the State Dinner. We took them at their word and filmed their preparations for the event. Half Yard Productions had no part in planning their presence at the event,” said Abby Greensfelder of Half Yard Productions.
Photos on the couple’s Facebook page they previously had gotten close to Obama. One photo, apparently taken in the days before Obama took the oath of office, shows the Salahis in a group shot with Obama and some of the musicians who performed at an inaugural concert.
Other photos show the Salahis in the empty, glass-enclosed box from which the Obamas watched the concert and, according to the caption, “backstage with the Secret Service at the Lincoln Memorial during the Presidential Inauguration.”
Associated Press writer Darlene Superville contributed to this report.


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A comparison of grassland butterfly fauna diversity in mown meadows and pastures under traditional grazing in Karelia, northwestern Russia and Finland
Published source details
Saarinen K. & Jantunen J. (2005) Grassland butterfly fauna under traditional animal husbandry: contrasts in diversity in mown meadows and grazed pastures. Biodiversity and Conservation, 14, 3201-3213
Published source details Saarinen K. & Jantunen J. (2005) Grassland butterfly fauna under traditional animal husbandry: contrasts in diversity in mown meadows and grazed pastures. Biodiversity and Conservation, 14, 3201-3213
This study is summarised as evidence for the following.
Maintain species-rich, semi-natural grasslandAction Link
Maintain species-rich, semi-natural grassland
A site comparison study of 12 pastures and meadows (4 ha) in northwest Russia and four in Finland (Saarinen & Jantunen 2005) found that butterfly (Lepidoptera) species richness, diversity and total abundance did not differ significantly between mown meadows and grazed pastures, although meadows were preferred by more species (46 vs 42). A total of 3,660 individuals were recorded in the meadows and 2,082 in pastures. Butterfly communities were affected more by the origin and age of the grassland than the present management method. Landscape factors such as surrounding habitat, abundance of nectar plants and intensity of tilling were the most important factors differentiating older grasslands from the younger ones. Meadows were mown annually in late July or August and pastures were grazed by cattle, some with sheep or horses temporarily. Tilling and fertilization (manure) tended to occur at intervals of 3-10 years. Butterflies were sampled 11-13 times along transects (640-720 m) in June and July 1997-1999.