text:
The campaign is called One You!
Why? Because we are all totally unique. We only have one life and our health has a profound effect on its quality and our level of happiness. It’s down to YOU to look after you.
Whether that’s help to lose weight by eating better, or help on how to stop smoking, or how to cut down on drinking or where and how to get active again, One You gives people the chance to reappraise their lifestyle choices, put themselves first and do something about their own health before it’s too late.
One You will help adults to move more, eat well, drink less, be smoke free, stress less and sleep better.
Without knowing it, by the time we reach our 40s and 50s many of us will have dramatically increased our chances of becoming ill later in life. Whether we are eating the wrong things, drinking more than we should, continuing to smoke despite everything we know, or just not being active enough, all of these small things can add up to an unhealthy you.
Making better choices today can have a huge influence on our health, and could prevent conditions like type 2 diabetes, cancer and heart disease, and reduce our risk of suffering a stroke or living with dementia, disability and frailty in later life.
But it’s not easy in our busy lives – tempting treats in easy reach, bigger portions for everything we eat and technology that allows us to shop, stay in touch and be entertained without ever having to leave the sofa. Modern life is ganging up on us.
The good news is we can fight back.
One You can help you get back to a healthier you, and support you to make simple changes towards a longer and happier life. One You will provide tools, motivational support and encouragement every step of the way, to help improve your health right away. You are not alone –One You has the tools and personalised support to help you make small changes yourself, or with friends and family.
A key engagement tool for One You will be the HAY Quiz. HAY is an online health quiz (not a medical diagnostic test), which Public Health England will be promoting through all of the national advertising during the launch of One You and beyond. It is a conversation starter for engaging people with their own health and gives them a brief idea of how they’re doing, as well as making suggestions about products and services they can use to change behaviours.
Search One You now www.nhs.uk/oneyou


Technology & Combat Characteristics
The Atmosphere Entry Transport is an unarmed transport capable of both space and atmospheric flight. For the purpose of reentry, its bow is fitted with four thruster nozzles, and it can deploy an inflatable heat shield from its front section. After entering the atmosphere, it can deploy the carried mobile suits from two hatches on its bottom.
The Atmosphere Entry Transport was used in A.C. 195 by OZ to transport their new frontline mobile suit, the OZ-02MD Virgo, across the Earth as part of Operation Nova, a campaign to destroy any resistance to its global unification efforts.
After OZ's Lunar Base was taken by the White Fang, they would continue to use the tmosphere Entry Transports to carry Virgos and their new WF-02MD Virgo II Mobile Dolls into battle against OZ's remaining space forces. Many Transports would be used during White Fang's attack on the Space Fortress Bulge.
On December 24th, A.C. 196, numerous Atmosphere Entry Transports were used by the Mariemaia Army to deploy the MMS-01 Serpent mobile suits from the resource satellite MO-III to Brussels, the capital of the Earth Sphere Unified Nation. Zechs Merquise, a member of Preventer, attempted to intercept them in the OZ-00MS2B Tallgeese III. However, he was only able to destroy three of them before he was stopped by Dekim Barton, who threatened to drop colony X-18999 onto Earth if he continued to attack.
- Mobile Suit Gundam - Ship & Aerospace Plane Encyclopedia - Revised Edition, p.222
- Encyclopedia of Gundam Wing, p.114
- The Eternal Flame of the Shooting Stars


text:
Maybe it has to do about the inflated valuations. At one San Francisco healthcare company, the head of strategy related to me that that his oncology technology development firm would be a multibillion dollar company in a few years. In a healthcare sensor company, that founder and CEO of a sensor related to me that his cancer diagnosis technology would generate hundreds of millions of dollars in a few years, while being distributed to research clinics and universities nationwide. His estimated valuation for his company also topped a billion dollars. At an international stem cell summit, the senior executive informed me that he raised over $2 billion through a State of California bond to fund clinical trials, and funded fifty such research firms while generating only $248 million. In fact, I have observed that every new technology or treatment related to oncology estimates that its valuation is over $1 billion. In the case of stem cell technologies, the scientists expect treatment costs to exceed $1 million per patient. But how realistic are these assumptions? Is the cure for cancer an inelastic model for every point in the value chain for treatment? Are these costs exploding because of the expensive scientific staffing? Does the high valuations from investors fuel this medical healthcare bubble? And are these realistic valuations for these companies?
Let’s start with some numbers: as of this year, the average American family earns around $56,000 a year. By looking at cancer treatments alone, currently 1,000,000+ patients are diagnosed with lung, thyroid, prostrate, breast, ovarian, leukemia, lymphoma, gastric, and bladder cancers in the US annually. And there about 25,000 medical clinics and over 2,000 colleges and universities – a fraction of which do any oncological research.
In the case of the $1 million cost for stem cell therapy, the estimated costs for treating all cancers described above in one year would be over $1,000,000,000,000 ($1 trillion or $1 million squared.) Let us compare this number against the total spent on healthcare. The per capita national health expenditures were: $9,523 (2014); the total national health expenditures: $3.0 trillion (2014). That would suggest that over third of all healthcare expenditures would be allocated to cancer treatment through stem cell treatment alone. Yet there other “cures” or diagnostic solutions in the same chain with the same revenue expectations.
But these GDP numbers are deceiving since they are spread across the whole population. By focusing only the narrow population suffering from cancer, we can honestly question where a population of over 1 million oncology patients can afford to pay for $1 trillion. And this is one part of the pyramid of services. In the case of the sensor, the company promises to show early diagnosis of cancerous cells. And the founder stated that the product would be distributed to clinics with revenues exceeding $300 million annually. In effect, each clinic is expected to pay over $12,000 for that sensor. That is calculated by dividing the number of clinics, 25,000, into the annual revenues exceeding $300 million, as stated in his projections. Again, how can the average family can afford such preventive or curative medicine when facing such daunting costs.
Why are these valuations and expectations so high? I once interviewed a CFO for a clinical trial group attempting to raise $10 million. The founding team, replete with academic degrees and currently employed by pharma companies, expected to retain over 80% of the company, although contributing not one dime. The founding team expected to be create the value on account of their expertise – even though I knew it was not unique. The company was not reducing costs
Now we should explore why such costs for the medical solutions there – investors requiring their ROI and under the standard Economic Value Added Analysis model, the ROI must exceed the cost of capital. With VC funds demanding double digit returns, they expect their portfolio companies to provide them their return.
Then comes their expensive, management teams. I personally know of one medical founder, entrepreneur, who holds a M.D., Ph.D., and a M.B.A. He lives well in Marin country. Another, a M.D. lives in Half Moon Bay. Many of these medical startups are founded by many with advanced degrees that, in ordinary marketplace, they would be well compensated. They expect the same, if not more, from their startup companies.
Yet, we expect that the average family can afford to pay for such services where each service provider for each portion of the stream of medical services is looking at over $1 billion worth of valuations. At the stem cell conference described earlier, the scientists were disappointed that the insurance carriers were not willing to reimburse medical costs exceeding $1 million. So we know that the price for healthcare is not inelastic, in other words, unlimited pricing. But where does society draw the line?

domain: news


text:
posted by Tim .
In this lab: we demonstrated the method of evaporation of a saturated sodium chloride solution.
The following question ask:
1) why is sodium chloride chosen for the solute?
2)Suggest reasons why the following were not chosen for the solute?
a)Calcium carbonate (CaCO3)=
b)Sodium Cyanide (NaCN)=
c)Gold Chloride (AuCl3)=
d)Hydrogen Chloride (HCl)=
a) is not very soluble in water
b) is poisonous
c) is too expensive
d) is volatile, dangerous to breathe, and does not leave a solid residue
I might use NaCl because it is cheap table salt and does not have the drawbacks of all the others suggested.

domain: chemistry


text:
... but I can't promise it'll be perfectly in key, as this month, it's all about demos!
If you've been reading this blog for awhile, then surely you've gathered a little about my recent creative frustrations. What follows is my attempt to break through that and hopefully move forward by spending a little time revisiting the past.
Welcome to A Song A Day in April, wherein I sift through and dust off old songs, new songs, and demos that have never seen the light of day (and perhaps, a few that never were *meant* to see the light of day!).
I'll mostly be posting previously unreleased demos, most of them largely unedited, many recorded moments after I wrote them, or even AS I was writing them, thanks to my participation in the Immersion Composition Society.
In some of my previous years of living, I've begun each year by writing one song each day for as long as I could manage to keep it going. But at this particular point in my life, I'm doing a lot of looking back.
April is the month of my birth, and possibly it’s purely coincidental that I'm turning 41 this month and so, perhaps, you could call this a part of my mid-life crisis, who knows? I've been feeling pretty creatively blocked over the last couple of years, and this project began in part because I was revisiting some of my orphaned songs in an attempt to get myself unstuck. In the process I realized that maybe I wasn’t stuck after all – maybe I was just working on finding my way.
Anyway, I discovered a few gems – and a few turds too – but mostly just had a great time revisiting the orphans! Some of them I may never want to revisit again, others may find their way into my live performances. For now, I'm just having fun digging through the old stuff, taking stock and working on finding a place from which to spring forward. I'm hoping that perhaps there are a few people out there who might appreciate this process and want to listen in.
Not sure where we're going to end up, but am looking forward to the journey, and would be delighted to have you riding shotgun with me.
And with that, here is today's song:

domain: artistic


text:
A Bergen County girl has filed go well with towards the homeowners of Retro Fitness, claiming she fell off a machine whereas exercising and landed on weights left on the ground by one other health club person.
Aysun Kahraman, 51, of North Arlington, says in courtroom papers she was significantly damage when she fell off an equipment and landed on dumbbells that one other individual had didn’t re-rack.
The incident occurred on Oct. 8, 2020, on the health club positioned within the 100 block of Schuyler Avenue in North Arlington, states the go well with, filed Oct. 7 in Superior Court docket of Bergen County.
“Kahraman was injured when utilizing a hamstring machine, (and) she was prompted to fall, hitting her head on dumbbells left on the ground,” the go well with states, including the lady’s accidents had been “critical and everlasting.”
The lawsuit alleges Retro Health and its staff had been answerable for protecting the premises freed from hazards.
A company spokesperson for Retro Health didn’t instantly reply on Friday to a request for touch upon the go well with.
Retro Health, which was based in 2005, has 175 gyms throughout the US and a number of places in New Jersey. The chain is the third largest within the “high-value, low-price” health enterprise, the corporate web site states.


text:
From the Hudson Valley Activist Newsletter #149A
Sept. 2, 2009, firstname.lastname@example.org, http://activistnewsletter.blogspot.com/
BROKEN LAWS, UNPROTECTED WORKERS
Tens of millions of low-wage workers in the United States are not only exploited but in many instances are criminally cheated by their bosses, according to a crucially important 72-page report released Sept. 2 and titled "Broken Laws, Unprotected Workers." The study, financed by the Ford, Joyce, Haynes and Russell Sage Foundations, is based on a survey of 4,387 workers in various low-wage industries. Following is the full executive summary of the report:
This report exposes a world of work in which the core protections that many Americans take for granted — the right to be paid at least the minimum wage, the right to be paid for overtime hours, the right to take meal breaks, access to workers’ compensation when injured, and the right to advocate for better working conditions — are failing significant numbers of workers. The sheer breadth of the problem, spanning key industries in the economy, as well as its profound impact on workers, entailing significant economic hardship, demands urgent attention.
In 2008, we conducted a landmark survey of 4,387 workers in low-wage industries in the three largest U.S. cities — Chicago, Los Angeles, and New York City. We used an innovative, rigorous methodology that allowed us to reach vulnerable workers who are often missed in standard surveys, such as unauthorized immigrants and those paid in cash. Our goal was to obtain accurate and statistically representative estimates of the prevalence of workplace violations. All findings are adjusted to be representative of front-line workers (i.e. excluding managers, professional or technical workers) in low-wage industries in the three cities — a population of about 1.64 million workers, or 15% of the combined workforce of Chicago, Los Angeles and New York.
Finding 1: Workplace Violations Are Severe and Widespread in Low-Wage Labor Markets
We found that many employment and labor laws are regularly and systematically violated, impacting a significant part of the low-wage labor force in the nation’s largest cities. The framework of worker protections that was established over the last 75 years is not working. Here we summarize only key violations.
Minimum wage violations:
• Fully 26% of workers in our sample were paid less than the legally required minimum wage in the previous work week.
• These minimum wage violations were not trivial in magnitude: 60% of workers were underpaid by more than $1 per hour.
• Over a quarter of our respondents worked more than 40 hours during the previous week. Of those, 76% were not paid the legally required overtime rate by their employers.
• Like minimum wage violations, overtime violations were of substantial magnitude. The average worker with a violation had put in 11 hours of overtime — hours that were either underpaid or not paid at all.
• Nearly a quarter of the workers in our sample came in early and/or stayed late after their shift during the previous work week. Of these workers, 70% did not receive any pay at all for the work they performed outside of their regular shift.
Meal break violations:
• The large majority of our respondents (86%) worked enough consecutive hours to be legally entitled to at least one meal break during the previous week. Of these workers, more than two-thirds (69%) received no break at all, had their break shortened, were interrupted by their employer, or worked during the break — all of which constitute a violation of meal break law.
Pay stub violations and illegal deductions:
• In California, Illinois and New York, workers are required to receive documentation of their earnings and deductions, regardless of whether they are paid in cash or by check. However, 57% of workers in our sample did not receive this mandatory documentation in the previous work week.
• Employers are generally not permitted to take deductions from a worker’s pay for damage or loss, work-related tools or materials or transportation. But 41% of respondents who reported deductions from their pay in the previous work week were subjected to these types of illegal deductions.
Tipped job violations:
• Of the tipped workers in our sample, 30% were not paid the tipped worker minimum wage (which in Illinois and New York is lower than the regular state minimum wage).
• In addition, 12% of tipped workers experienced tip stealing by their employer or supervisor, which is illegal.
Illegal employer retaliation:
We found that when workers complained about their working conditions or tried to organize a union, employers often responded by retaliating against them. Just as important, many workers never made complaints in the first place, often because they feared retaliation by their employer.
• One in five workers in our sample reported that they had made a complaint to their employer or attempted to form a union in the last year. Of those, 43% experienced one or more forms of illegal retaliation from their employer or supervisor. For example, employers fired or suspended workers, threatened to call immigration authorities, or threatened to cut workers’ hours or pay.
• Another 20% of workers reported that they did not make a complaint to their employer during the past 12 months, even though they had experienced a serious problem such as dangerous working conditions or not being paid the minimum wage. Half were afraid of losing their job, 10% were afraid they would have their hours or wages cut, and 36% thought it would not make a difference.
Workers’ compensation violations:
We found that the workers’ compensation system is not functioning for workers in the low-wage labor market.
• Of the workers in our sample who experienced a serious injury on the job, only 8% filed a workers’ compensation claim.
• When workers told their employer about the injury, 50% experienced an illegal employer reaction — including firing the worker, calling immigration authorities, or instructing the worker not to file for workers’ compensation.
• About half of workers injured on the job had to pay their bills out-of-pocket (33%) or use their health insurance to cover the expenses (22%). Workers’ compensation insurance paid medical expenses for only 6% of the injured workers in our sample.
When workers are exempt from workplace laws:
• Some workers are either partially or completely exempt from employment and labor laws —either because of archaic exemptions of specific industries and occupations, or because they are considered to be independent contractors.
• We surveyed one group of workers that is often considered exempt from coverage: "in-home" child care workers who provide care in their own homes. When we analyzed their working conditions (separately from the rest of the sample), we found that 89% earned less than the minimum wage. This finding underscores the need to ensure that all workers who are in an employment relationship receive full legal protection.
Finding 2: Job and Employer Characteristics Are Key to Understanding Workplace Violations
Workplace violations are ultimately the result of decisions made by employers — whether to pay the minimum wage or overtime, whether to give workers meal breaks, and how to respond to complaints about working conditions. We found that workplace violations are profoundly shaped by job and employer characteristics.
• Violation rates varied significantly by industry. For example, minimum wage violation rates were most common in apparel and textile manufacturing, personal and repair services, and in private households (all of which had violation rates in excess of 40%). Violation rates were substantially lower in residential construction, social assistance and education, and home health care (at 12% to 13%). Industries such as restaurants, retail and grocery stores, and warehousing fell into the middle of the range, with about 20% to 25% of their workers experiencing a minimum wage violation.
• Violation rates also varied significantly by occupation. For example, childcare workers had very high minimum wage (66%) and overtime (90%) violation rates. More representative were occupations such as cashiers, who had a minimum wage violation rate of 21% and an overtime violation rate of 59%.
• Workers who were paid a flat weekly rate or paid in cash had much higher violation rates than those paid a standard hourly rate or by company check.
• Workers at businesses with less than 100 employees were at greater risk of experiencing violations than those at larger businesses. But workers in big companies were not immune: nearly one in six had a minimum wage violation in the previous week, and of those who worked overtime, 53% were not paid time and a half.
• Not all employers violate the law. We found a range of workplace practices — offering health insurance, providing paid vacation and sick days, and giving raises — that were associated with lower violation rates. This suggests that employers’ decisions about whether or not to comply with the law are part of a broader business strategy shaping the workplace.
Finding 3: All Workers Are at Risk of Workplace Violations
Workplace violations are not limited to immigrant workers or other vulnerable groups in the labor force — everyone is at risk, although to different degrees.
•Women were significantly more likely than men to experience minimum wage violations, and foreign-born workers were nearly twice as likely as their U.S.-born counterparts to have a minimum wage violation.
• The higher minimum wage violation rate for foreign-born respondents was concentrated among women—especially women who are unauthorized immigrants.
• Foreign-born Latino workers had the highest minimum wage violation rates of any racial/ethnic group. But among U.S.-born workers, there were significant race differences: African-American workers had a violation rate triple that of their white counterparts (who had by far the lowest violation rates in the sample).
• Higher levels of education, longer job tenure, and English proficiency (for immigrants) each offered some protection from minimum wage violations. But even college-educated workers and those who had been with their employers for five or more years were still at significant risk.
• Overtime, off-the-clock and meal break violations generally varied little by worker characteristics. On the whole, job and employer characteristics were more powerful predictors of the workplace violations considered in this study.
Weekly Wage Theft in America’s Cities
Wage theft not only depresses the already meager earnings of low-wage workers, but also adversely impacts their communities and the local economies of which they are a part.
•Workers: More than two-thirds (68%) of our sample experienced at least one pay-related violation in the previous work week. The average worker lost $51, out of average weekly earnings of $339. Assuming a full-time, full-year work schedule, we estimate that these workers lost an average of $2,634 annually due to workplace violations, out of total earnings of $17,616. That translates into wage theft of 15% of earnings.
• Communities: We estimate that in a given week, approximately 1,114,074 workers in the three cities combined have at least one pay-based violation. Extrapolating from this figure, front-line workers in low-wage industries in Chicago, Los Angeles and New York City lose more than $56.4 million per week as a result of employment and labor law violations.
Fulfilling the Promise of Worker Protections in America
Everyone has a stake in addressing the problem of workplace violations. When impacted workers and their families struggle in poverty and constant economic insecurity, the strength and resiliency of local communities suffer. When unscrupulous employers violate the law, responsible employers are forced into unfair competition, setting off a race to the bottom that threatens to bring down standards throughout the labor market. And when significant numbers of workers are underpaid, tax revenues are lost.
Three principles should drive the development of a new policy agenda to protect the rights of workers.
• Strengthen government enforcement of employment and labor laws: Public policy should leverage the resources and power that reside in agencies responsible for enforcing worker protections. This will require additional staffing, but more important, new strategies are needed to address the reality that workplace violations are becoming standard practice in many low-wage industries.
• Update legal standards for the 21st century labor market: Weak employment and labor laws open the door to low-road business strategies focused on illegally cutting labor costs. Raising the minimum wage, updating health and safety standards, ending exclusions that deny workers coverage, and strengthening the right of workers to organize through labor law reform — all are key improvements that would raise compliance in the workplace and improve the competitive position of employers who play by the rules.
• Establish equal status for immigrants in the workplace: The best inoculation against workplace violations is ensuring that workers know their rights, have full status under the law to assert them, have access to sufficient legal resources, and do not fear retaliation. But for unauthorized immigrant workers today, this can be a near impossibility. Any policy initiative to reduce workplace violations must prioritize equal protection and equal status in national immigration reform, and ensure status-blind enforcement of employment and labor laws.
[Editor's Note: This report is a shocking revelation about the extent of the super exploitation of huge number of American workers. It should make us all very angry. But we doubt the government in Washington will do much about it except for some lofty pronouncements and the ostentatious wringing of hands. A small, somewhat left minority in Congress will demand action, but it has no power. That's how the system works, and the only way to substantially change things is to change the system to one that puts people before profits. In our view this won't change until we install a left government.]

domain: sociology


text:
File Chapter 7 Bankruptcy for a Fresh Financial Start
At DeWald Law Offices in Bethlehem, PA, we can help you file for bankruptcy. Attorney Michelle DeWald works closely with you to determine the best option for your particular situation.
Chapter 7 bankruptcy offers a fresh start financially. You can get rid of dischargeable debts, and relieve some of your financial burden.
Credit card debt
Medical bill debt
What is Chapter 7 Bankruptcy?
Chapter 7 is commonly known as a ‘straight bankruptcy'. It is a quick process that usually takes a few months. Chapter 7 bankruptcy works best for individuals who:
Have high credit card debt
Have unexpected medical bills
Receive collection calls
Receive financial notices
Not enough income to pay bills
Low credit score
Are being sued by creditors
Start Your Debt Relief Today
No matter how well we manage money, problems arise unexpectedly that can have a severe impact on our lives.
Divorce, unemployment and unexpected medical expenses are all issues that can drain your resources.
Consult with our Chapter 7 Bankruptcy attorney to evaluate your situation and provide some options to help you regain financial stability for you and your family.

domain: economics


text:
Money is tight for most American families and summer vacation is here.
Here are 6 quick tips to travel further with your dollar.
1. Use traveler’s checks.
Set aside a certain amount for each day and stick to the budget. Having to sign each check before the purchase is made will help you be much more conscious of your spending than if you use a credit card.
2. Visit locally and day trip to a few different locations.
There are many great attractions within a day’s drive of just about any point in the U.S. Get creative and explore areas within an hour of home.
3. Visit a state park, national park, or a museum.
Many museums, state and national parks offer free or inexpensive admission. Take advantage of these low-cost educational attractions, after all your taxes pay to run many attractions.
4. Travel mid week to take advantage of coupons or specials.
Coupons and specials can be a great way to reduce costs, traveling during non peak times can also be a great way to get a deal.
5. Split the cost.
It may sound funny, but going dutch and traveling with another family can be a great way to reduce travel expenses.
6. Pack your dinner.
Many times the best specials can be had for lunch. Eating out for lunch only and dining in for dinner is a great way to reduce costs. One idea is to invest in a travel cooler that plugs in to your cars accessory outlet and can keep food refrigerated all day.

domain: travel


Research, review, and buy Usb Video Card Usb 3.0 To Hdmi Graphics Adapter 4k. Startech.com USB32HD4K is available for $83.72. More information on this item is available below. Click the button below for details and specifications.
Startech.com USB32HD4K Usb Video Card Usb 3.0 To Hdmi Graphics Adapter 4k
View availability and more information >>
From here, you can purchase this product in our Online Catalog. You can also browse BLT's Online Catalog, search BLT's catalog or visit BLT's home page.
Note: This information is provided by a third party as a courtesy. You may wish to consult the manufacturer's website to verify this information. This is all the information we have for this item. If you need more or wish to verify the accuracy of this information, please contact the manufacturer.
Want to add 4K Ultra HD video to your computer system? Now, you can enjoy the picture quality of Ultra HD video, even if your system doesn't natively support 4K video output.
With an additional 4K monitor connected to your computer, you can extend or mirror your desktop for increased productivity. DisplayLink 4K Plug-and-Display certification ensures automatic driver installation, so you'll be ready to enjoy your Ultra HD display in no time.
Ultra HD Multi-tasking
Now you can connect a 4K HDTV, monitor or projector to your computer, even if your laptop or desktop video card doesn’t natively support 4K output. The USB32HD4K USB to HDMI 4K adapter lets you extend or mirror your primary display onto an Ultra HD monitor or television, giving you the additional screen space you need to simplify multi-tasking and maximize your productivity.
Astonishing 4K Picture Quality
At four times the resolution of high-definition 1080p, you’ll be amazed at the picture quality of a 4K monitor or television; the USB32HD4K lets you harness the impressive bandwidth capability of a USB 3.0 connection to deliver the astonishing quality of Ultra HD to your 4K display. Plus, the adapter is backward compatible with 1080p displays, which makes it a great accessory for home, office or other workspace applications.
DisplayLink 4K Plug-and-Display Certified
Installation has never been easier. When you connect this DisplayLink 4K Plug-and-Display certified adapter to a web-enabled Windows® 7, Windows® 8 or Windows® 10 computer, it automatically downloads and installs the most up-to-date drivers for you, so you won’t have to.
The USB32HD4K is backed by a StarTech.com 2-year warranty and free lifetime technical support.
The StarTech.com Advantage
- Enable 4K video output from your computer system to an HDMI television. The USB 3.0 to HDMI 4K adapter allows your system to output 4K video even if your system is not capable of outputting Ultra HD resolutions
- Now you can add an additional 4K television, by simply plugging the USB32HD4K into a USB 3.0 port
- Get up and running faster, with automatic software & driver installation on computers running Windows 10, 8, or 7 with an active Internet connection
The electrical or electronic product contains little or no Hazardous Substances (RoHS). Any RoHS compliant product is tested for the presence of Lead (Pb), Cadmium (Cd), Mercury (Hg), Hexavalent chromium (Hex-Cr), Polybrominated biphenyls (PBB), and Polybrominated diphenyl ethers (PBDE). PBB and PBDE are flame retardants used in several plastics. For Cadmium and Hexavalent chromium, there must be less than 0.01% of the substance by weight. For Lead, PBB, and PBDE, there must be no more than 0.1% of the material. Any RoHS compliant component must have 100 ppm or less of mercury and the mercury must not have been intentionally added to the component.
|BLT Item #:||BYB0626|
|Manufacturer Part #:||USB32HD4K|
|Description:||USB VIDEO CARD USB 3.0 TO HDMI GRAPHICS ADAPTER 4K|
|Suggested Retail Price:||$117.99|
|Dimensions:||8.1" x 5.6" x 1.5"|
|Return Policy:||Standard BLT Return Policy|
|Brand and Item Information|
|Name:||StarTech.com USB32HD4K 3840 x 2160pixels Black USB graphics adapter|
|Brief Description:||StarTech.com USB32HD4K, 3.0 (3.1 Gen 1), USB Type-A, Male, 3840 x 2160 pixels, 640 x 480 (VGA), 1024 x 768 (XGA), 1280 x 1024 (SXGA), 1280 x 720 (HD 720), 1280 x 768 (WXGA),..., 480p,720p,1080p,2160p|
|Expanded Description:||StarTech.com USB32HD4K. USB version: 3.0 (3.1 Gen 1), USB connector type: USB Type-A, USB connector gender: Male. Color of product: Black, Housing material: Plastic, USB cable length: 2.36" (0.0600 m). Windows operating systems supported: Windows 10 Education,Windows 10 Education x64,Windows 10 Enterprise,Windows 10 Enterprise..., Mac operating systems supported: Mac OS X 10.10 Yosemite,Mac OS X 10.11 El Capitan,Mac OS X 10.6 Snow Leopard,Mac OS X 10.7..., Minimum processor family: Core i5. Width: 1.77" (45 mm), Depth: 7.87" (200 mm), Height: 0.591" (15 mm)|
|Windows operating systems supported:||Windows 10 Education,Windows 10 Education x64,Windows 10 Enterprise,Windows 10 Enterprise x64,Windows 10 Home,Windows 10 Home x64,Windows 10 Pro,Windows 10 Pro x64,Windows 8,Windows 8 Enterprise,Windows 8 Enterprise x64,Windows 8 Pro,Windows 8 Pro x64,Windows 8 x64,Windows 8.1,Windows 8.1 Enterprise,Windows 8.1 Enterprise x64,Windows 8.1 Pro,Windows 8.1 Pro x64,Windows 8.1 x64,Windows Vista Home Premium,Windows Vista Home Premium x64,Windows Vista Ultimate,Windows Vista Ultimate x64,Windows XP Home,Windows XP Home x64,Windows XP Professional,Windows XP Professional x64|
|Mac operating systems supported:||Mac OS X 10.10 Yosemite,Mac OS X 10.11 El Capitan,Mac OS X 10.6 Snow Leopard,Mac OS X 10.7 Lion,Mac OS X 10.8 Mountain Lion,Mac OS X 10.9 Mavericks|
|Minimum processor family:||Core i5|
|Minimum processor speed:||2.4 GHz|
|Minimum RAM:||4 GB|
|Weight & Dimensions|
|Width:||1.77" (4.50 cm)|
|Depth:||7.87" (20.00 cm)|
|Height:||0.591" (1.50 cm)|
|Weight:||0.44 lbs (200 g)|
|Package width:||5.67" (14.40 cm)|
|Package depth:||8.27" (21.00 cm)|
|Package height:||1.5" (3.80 cm)|
|Package weight:||0.44 lbs (200 g)|
|Operating temperature (T-T):||0 - 40 °C|
|Storage temperature (T-T):||-10 - 80 °C|
|Operating relative humidity (H-H):||0 - 85 %|
|Color of product:||Black|
|Integrated USB cable:||Y|
|USB cable length:||2.36" (0.06 m)|
|USB version:||3.0 (3.1 Gen 1)|
|Number of displays supported:||1|
|USB connector type:||USB Type-A|
|USB connector gender:||Male|
|Maximum resolution:||3840 x 2160 pixels|
|Supported graphics resolutions:||640 x 480 (VGA), 1024 x 768 (XGA), 1280 x 1024 (SXGA), 1280 x 720 (HD 720), 1280 x 768 (WXGA), 1280 x 800, 1366 ? 768, 1400 x 1050 (SXGA+), 1600 x 1200 (UXGA), 1680 x 1050 (WSXGA+), 1920 x 1080 (HD 1080), 1920 x 1200 (WUXGA), 2048 x 1152, 3840 x 2160|
|Supported video modes:||480p,720p,1080p,2160p|
|Chipset:||DisplayLink - DL5500|
|Certification:||CE, FCC, DisplayLink|
Free ground shipping in the contiguous 48 United States on most orders over $1,000.00!
This page about Startech.com USB32HD4K Usb Video Card Usb 3.0 Hdmi Graphics Adapter 4k 065030859271
is copyrighted © 2018 Bottom Line Telecommunications, Inc. All Rights Reserved.
No portion of this document may be modified, copied, distributed, or reused in any way without the expressed written consent of Bottom Line Telecommunications, Inc. Every effort has been made to ensure the accuracy of information displayed, however we are not responsible for typographical and pricing errors. Pricing fluctuates rapidly on certain items making 100% accuracy impossible. Price and availability are subject to change without notice. Incorrect pricing will not be honored. Product images, descriptions, and specifications are provided as a courtesy and should not be relied upon to accurately describe an item. Consult the manufacturer's website for complete information on an item before purchasing. Current site time: 04:45:07 on 04/21/2018.


text:
Reactivity Indexes of Fullerene and Bismullene Mixed Clusters: How the Intruders Modify the Properties
journal contributionposted on 19.10.2016, 00:00 by Ana Martínez
In this investigation, the feasibility of functionalizing fullerene and bismullene with Bi and C as intruders is theoretically explored. The systems analyzed are C60–xBix (with x = 0–10, fullerene-like) and Bi60–yCy (with y = 0–10, bismullene-like). Optimized geometries, reactivity indexes, and highest occupied molecular orbital to lowest unoccupied molecular orbital (HOMO–LUMO) gaps (for analyzing the potential application of these molecules as materials for solar cells) are reported. The most stable structures of bismullene-like systems have cage geometries. The most stable fullerene-like geometries resemble a cup with bismuth atoms at the edge of the bowl. The presence of intruders increases the electron acceptor power and decreases the electron donor power in most cases. HOMO–LUMO gaps indicate that bismullene-like clusters represent better candidates for building solar cells than fullerene-like clusters. This information could be useful for future experiments.
Read the peer-reviewed publication
Intruders Modifycage geometriesHOMOelectron donor powerreactivity indexesintruders increasesfullerene-like clustersfuture experimentsfunctionalizing fullerenebismullene-like clustersOptimized geometriesReactivity Indexeselectron acceptor powergapbismuth atomsfullerene-like geometriesBismullene Mixed Clustersbismullene-like systems


text:
5 edition of A brand new doctor found in the catalog.
|Statement||by R.S. Devney.|
|Series||American fiction -- reel 47, no. 439.|
|Contributions||Putnam, F. O., Hughes, James E.|
|The Physical Object|
|Pagination||176,  p.,  leaves of plates|
|Number of Pages||176|
Introductory Health Consultation. Evan works with adults and children of all ages. Start addressing the root cause instead of masking the symptoms. Follow the simple steps to see if Evan Brand can help you. Step 1. Click here to schedule your minute complimentary consult. List your top 3 health challenges on your appointment form so we know. Their success boils down to 3 simple keys – and inside this brand-new book I’ll reveal each key in depth, which will enable you to dramatically increase your practice profits without buying expensive new equipment without hiring additional staff and without spending far more money on marketing and advertising GUARANTEED.
The Official Quiz Book Over pages with 3, questions from across Space and Time A must for Doctor Who fans Unwanted present Brand New, The next day, this brand-spanking-new company was “featured at a large health care tech conference being run by the U.S. Department of Health and Human Services (HHS), and StartUp Health executives became regular visitors to the White House, attending events in , and ” In March , Biden went to Costa Rica.
From Maria Goodavage’s brand new book Doctor Dogs, an excerpt in Wired probes the FIDO program at Georgia Institute of Technology’s Animal-Computer Interaction Lab. The epicenter of dog-human Author: David Graver. Apple Footer * Trade‑in value based on inch MacBook Pro. Trade‑in values will vary based on the condition, year, and configuration of your trade‑in device. You must be at least 18 years old to be eligible to trade in for credit or for an Apple Store Gift Card.
Relationship of the Latin facetus literature to the medieval English courtesy poems
The little bookroom
The U.S. and China
One pups up
The American conscience
Stories of Birbal
University of Maryland trivia book
From gospel to rap
Moving in Ohio
Brand New Day offers a network of primary care doctors, specialists, hospitals, and other healthcare providers. You must receive all routine care from in-network plan providers except for emergent or urgent care situations or for out-of-area renal dialysis.
Books Advanced Search New Releases Best Sellers & More Children's Books Textbooks Textbook Rentals Best Books of the Month There's a problem loading this. Comment: UNused book w/ minor ding/s. Click Read More for condition details, which is that this book is from a bookstore that didnt sell it.
That is, this is a brand new book that has never been sold, read or used, but note: it does have some small, but noticeable cosmetic damage, like a cover crease or mark on the cover, or a damaged dust jacket or bent pages/5(93).
Great deals on Hardcover Fiction & Literature Books. Get cozy and expand your home library with a large online selection of books at Fast & Free shipping on many items. The lowest-priced brand-new, unused, unopened, undamaged item in its original packaging (where packaging is applicable).
Packaging should be the same as what is found in a retail store, unless the item is handmade or was packaged by the manufacturer in /5(69). Discover the cream of brand new publishing with the very latest titles from the worlds of fiction, non-fiction and children’s.
From the biggest new books by the hottest authors to word-of-mouth releases destined to become future classics, these great volumes are all out now. Brand New Day is an HMO SNP with a Medicare contract.
Enrollment in Brand new Day depends on annual contract renewal. H_BNDWeb. Best Buys on Brand New Books Explore our selected new books and discover literature that have everyone talking. Check back often - our featured new books are regulary updated with the latest and greatest bestselling books in fiction and non-fiction by famous.
The New Series Adventures are a series of novels relating to the long-running BBC science fiction television series, Doctor 'NSAs', as they are often referred to, are published by BBC Books, and are regularly published twice a ing with the Tenth Doctor, a series of 'Quick Reads' have also been available, published once a exception to the Quick Reads, all of the.
Browse a wide variety of new book releases at Barnes & Noble. Shop for your new favorite books online and have them shipped to you or pick them up in store. Due to COVID, orders may be delayed.
() W Davis St Dallas, TX /5(10). 'Brand New You' is a self help book that is written by a man who achieved a lot of his ambitions, but felt that he could have reached his goals more quickly, had he known what he knows now.
It took him 20 years to become a performer, 30 years to run a business of his own and 40 years to become a writer.4/5. The new Doctor Aphra series, written by Alyssa Wong with art by Marika Cresta, gives Aphra a new crew and a new mission set during the era between Star Wars: The Empire Strikes Back and Author: Jamie Lovett.
Millions of new, used, rare, and out-of-print books are offered for sale on from thousands of booksellers around the world. We have the best selection of cheap books, both new and used, many as low as a r you are looking for big discounts on the hottest new titles, cheap textbooks, or you want a used paperback, is your best bet to buy cheap books online.
Dr. Seuss returns with newly discovered book. Seuss long ago passed from the scene but old manuscripts by the beloved children's author keep turning up.
Lists about: Medicine and Literature, I Love A Man In Uniform, Best Books for Medical Students, Doctor/Medical Romance Heroes, Best Gay Doctors, Best Boo. Brave New Medicine details the disabling autoimmune illness that forces a young doctor to question her medical training, embrace the principles of integrative and functional medicine, and unlock her body’s innate potential to heal.
In this revelatory memoir, Li blends the insight of a scientist with the humility and candor of a patient, drawing upon cutting-edge science. Last Updated: May 7, There’s no denying that the most popular genre around these days is the superhero movie.
Christopher Nolan’s Dark Knight Trilogy proved that comic book adaptations. The Brand Doctor Growth Club is a handful of accept-no-limits entrepreneurs will get the knowledge and guidance to rock their businesses this year.
BOOK A CONSULT. Inside the “Brand. Branding Your Business Promote Your Business Attract Customers Build Your Brand Through The Power Of Emotion Branding Your Business was published in as part of the Sunday Times Business Enterprise Series.
Within days, it was getting serious reviews. In less than two months, it had become BrandChannel‘s Book of the Month. Init [ ]. In stores now is a new original Doctor Who novel which goes back to The Tenth Doctor era in Series Four, when his travelling companion was the fastest temp in the universe, Donna Noble.
In The Blood pits the pair together once more and is written by Jenny T Colgan, who has recently written for David Tennant and Catherine Tate in their recent.The Who star-studded live announcement – the first time a new Doctor has been announced with such fanfare – was reportedly a quasi-last minute decision by new BBC1 controller Charlotte Moore.Coupons & Deals Book Annex Buy 1, Get 1 50% Off: Books for All Ages Bestsellers 30% Off Hardcover New Releases from 20% Off Customer Favorites New Releases Coming Soon Boxed Sets Signed Books Books by Author Book Awards Celebrity Book Clubs & More Read Before You Stream Best Books of the Year B&N Classics B&N Collectible Editions B&N Exclusives.

domain: library


text:
Eterna Therapeutics’ team of scientists and physicians are pioneers in using synthetic mRNA, cellular reprogramming, gene editing, and other cutting-edge technologies. Eterna Therapeutics’ mRNA Cell Engineering offers the theoretical ability to repair any cellular dysfunction. We plan to market a variety of therapeutics based on combining and refining the best attributes of these cutting-edge technologies.
Messenger RNA (mRNA) designates a special class of molecules containing instructions that determine how cells function. The same technology that helped create coronavirus vaccines can be used to treat other diseases by repairing disease-causing mutations and directing the formation of stem cells.
Eterna Therapeutics taps into the expertise of a number of partner companies, including Factor Bioscience, Exactis Biotherapeutics, MD Anderson, and the National University of Ireland, to aid in the research and development of mRNA gene-editing technology, mRNA delivery systems, and next-generation mRNA vaccines. Eterna Therapeutics is well on its way for the creation of a family of patent-protected mRNA-based therapeutics.
Messenger RNA (mRNA) carries the instructions contained in DNA to the cellular machinery that translates these instructions into functional proteins. Eterna makes mRNA with various chemical and structural enhancements (e.g., immuno-stealthing modifications, circular formats, etc.), and uses these molecules to improve cell function.
Eterna formulates mRNA using lipid nanoparticle (LNP) technology. The ToRNAdo™ delivery system surrounds and protects the mRNA cargo, enabling efficient delivery into human cells.
Eterna uses mRNA to express gene editing proteins. These proteins are capable of deactivating, repairing, inserting, or replacing specific DNA sequences in living cells to repair genetic damage and confer new functionality to cells.
Eterna uses mRNA to express reprogramming proteins. These proteins re-write a cell’s gene expression program, enabling a somatic cell, such as a skin cell, to transform into another type of cell, such as a neuron or a stem cell. In one application of this technology, Eterna makes induced pluripotent stem (iPS) cells, a cell type that can differentiate into any needed cell.

domain: medical


text:
Deep bench an asset for Warrior girls
FORT KENT, Maine – The Fort Kent Community High School Warrior girls varsity basketball team has no shortage of talented players this year.
The team features 18 athletes, giving Coach Kelly O’Leary plenty of choices to draw from when formulating game plans.
Last season, Fort Kent finished 9-7 during the regular season, earning the Warriors the sixth seed in Class C North. Fort Kent beat No. 11 Mattanawcook Academy, 51-42, earning a chance to play at the Cross Insurance Center in Bangor. Fort Kent lost to No. 3 Penobscot Valley, 38-24, in the quarterfinals.
O’Leary, who is in his eighth year coaching the Fort Kent girls, said this year’s team has “a lot of talent.”
“Team depth and defense will be keys moving forward,” O’Leary said.
The Fort Kent Warrior girls are: Seniors Larissa Daigle and Genevieve Naranja. Juniors Julia Cyr, Hannah Lovley, Madeline Philbrook, Emila Voisine and Emma Caron. Sophomores Lily Oliver, Lily Werntgen, Maddie Morneault, Amari Weaver, Anna Durost, Ellie Roy and Isabelle Sterris. Freshman Emlyn Nadeau, Brooke Kelly, Katherine Michaud and Gracie Landry.
As far as team improvement goes, O’Leary said individual skill development is key.
“We will play a 12 man rotation and develop the team as the season goes along,” he said.
Last year the Warriors saw a postseason trip to Bangor where they fell to Penobscot Valley in the Class C North quarterfinals.
Caribou, Hodgdon, Southern Aroostook and Wisdom are going to be competitive programs who will provide the Warriors with some stiff competition on the road to the playoffs this year, O’Leary said.
The team lost senior captains Kassidy O’Leary and Allie Morgan to graduation last year.
Fort Kent recreation and parks director Jason Nadeau has stepped in to take on the role of assistant coach. Nadeau coached the Valley Rivers Middle School team, including all of the freshmen and sophomores on this year’s varsity team.
In keeping with his coaching style, O’Leary has not identified a starting lineup and will be determined on a game by game basis depending on the Warriors opponents.


Audio Research - March 13, 2014
- Written by Doug Schneider Doug Schneider
- Parent Category: Company Tours Company Tours
- Created: 13 March 2014 13 March 2014
After the circuit boards are completed, they make their way to an adjacent area in the factory called chassis assembly, which is where the products begin to take shape. It's in this area that the boards are installed, connectors are attached, wiring is completed, and various parts are installed to create a fully functioning product ready for testing.
Carts of partially completed products.
Attaching a fan to Reference 150 stereo amplifier.
Soldering leads to the connectors on a Reference 10 preamplifier chassis.
Attaching the connectors for a VSi75 integrated amplifier chassis.
Brandon Lauer, Audio Research's marketing manager, holds a custom-designed transport mount for the CD6 and Reference CD9 disc players.
The Reference CD9 with transport, boards, connectors, and wires attached.
Wire bundling for the Reference 750 mono amplifier
Board installation and final wiring for a Reference 5 SE preamplifier.
Publisher, The SoundStage! Network
Most-Read Last 90 Days
- Magico M9 Loudspeakers: No Compromises Allowed
- Audeze's CRBN: An Actual Game-Changer in High-End Headphones?
- From Monitor Audio Studio to Gold 100 Loudspeakers: Part 4
- Heal Our Land—The Concert
- The Technics SU-R1000: Fully Digital Tour de Force Integrated Amplifier Plays Records
- Temple Audio: In a Class of its Own
- Unboxing the SVS SB16-Ultra Subwoofer


text:
TADAA -- Teen Alcohol and Drug Abuse Awareness is a one-day workshop designed to empower high school students to take an active role in keeping their school campus and community alcohol and drug abuse free.
Mobile and Baldwin County high schools are invited to select two seniors, two juniors, two sophomores, and two freshmen, along with one faculty member to attend this day of education and awareness. Presentations during the day will enable participants to develop an effective and unique plan to end alcohol and drug abuse on their school campus.
TADAA 2020 was held on January 23rd at the Gulf Quest Museum, with over150 student and faculty participants from 23 schools
across Mobile and Baldwin Counties. In addition to the workshop presentations by former NFL player Steve Fitzhugh, students enjoyed having the opportunity to hear from Coast Guard representatives about the role of the Coast Guard in drug interdiction and prevention and to tour the MANOWAR ship.


Garage Door Repair Toronto 416-639-1999
Star Garage Doors offers garage door repair in Toronto and surrounding GTA, garage door sales, service, parts, new garage doors, garage door installations, garage door panel repairs, garage door springs, and more. With our trusted technicians, always stocked with parts and panels. We are able to get to your home in a few hours and your garage door fixed asap. Fill out the form or give us a call at our local Toronto garage door repair number 416-639-1999
Click this link to read more about Garage door repair in Toronto.
Our Toronto garage door repair technicians provide fast and friendly garage door service, including maintenance, installations, and repairs across the GTA. We can repair Sectional, Overhead, Steel, Metal, Patio, Roll-up, Cedar, Insulated, Carriage House, Composite, Aluminum, Cladwood & Iron Garage Doors. Our technicians are always open to your concerns and do their job efficiently. Click here to ready more about new garage door installation in Toronto
When you call on Star Garage Door, you can rest assured an experienced professional will arrive at your home with all the necessary equipments. After determining the problem, first of all, we will provide a written estimate and our plan of action to solve your garage door issue. Our technicians will walk you through the entire repair or installation process so that you can be confident about our services and your door.
Our round-the-clock services and the industry’s best warranty keep us ahead in Toronto’s competitive market. Some leading brands that you will find in our arsenal of garage doors include Amarr, Raynor, Lynx, Clopay, Wayne Dalton, LiftMaster, Garaga, Haas, Genie, Chamberlain, Stanley, Craftman, Sear.
Garage Door Repair Toronto Services – Sales, Replacement, Opener & Installation Services
- Residential, Commercial & Industrial Garage Doors
- Garage Doors Annual Maintenance Services
- 24/7 Emergency Repair – 365 Days a Year
- Buy Original Parts & Spares of Garage Doors
- Panel, Hinges, Gears, Roller Brackets, Tracks Replacement
- Broken Garage Doors Cable Repair
- Extension & Torsion spring Repair replacement
- Garage Door Weather Seal Stripping & Broken Motors
- Fix Pulley Systems, Cable Drums, Break-Ins or Vandalism
- Emergency Lock & Keypad Service
- Screw Drive Opener
- Belt Drive Opener
- Direct Drive Opener
- Chain Drive Opener
- Overhead door opener
- Residential & Commercial Garage Door Openers
- Opener Repair, Installation & Replacement
- Automatic & New garage door installation
- Fix Garage Door Openers
Why do homeowners choose Star Garage Door to repair their garage door in Toronto?
Star Garage Door in Toronto has the best team of skilled technicians that provides high quality services in the Toronto area. With our excellent garage door repair, installation and maintenance services, we aim to gain trust of our customers. We use the most advance technology and employ experienced technicians who offer high end services at affordable prices. We are competent of handling all makes and models of garage doors. Our technicians know how to get the job done right the first time. We provide:
- Trustworthy, Reliable and High Quality Service
- Local Technicians for Timely and Cost Effective Garage Door Repairs
- Customer Satisfaction Guaranteed
- Licensed, Highly Trained, Experienced Repair Technicians
- Emergency 24-Hour Garage Door Repair Services for Commercial & Residential Settings
Star Garage Door guarantees fast and high quality services for garage door installation, garage door opener, rollers, and springs to our residential and commercial customers. Our customers can count on us for 24 hour emergency garage door repair, installation and maintenance services across Toronto.


text:
Eighty Clicks offers four different game modes:
- Multiple Choice: the default, pick the correct country/province/state from a list.
- Classic: Put a marker on the map as close as possible to the panorama location. 5 turns.
- No Wander: Like classic, but you can't move
- Perfect Streak: Like classic, repeating until you fail to get 1000 points
Perfect streak was one of the reasons I created Eighty Clicks. I love the puzzle of getting to within yards of the exact location of the panorama. Frankly, I had no idea if any one was playing this game mode (or any of the other game modes).
Preditably, as the default Multiple Choice is the most popular game mode. Classic mode is not far behind. Perfect Streak seems like the least popular mode, but on some of these games last much longer than the other game modes. In fact, the longest completed perfect streak has 707 different locations! If you think that is a lot (it is), there currently are several running games with even more visits. That's truly impressive.
Technically, Multiple Choice consists of three types of modes: On the world map, you need to guess the correct country. On country maps, you need to guess the correct province/state/subdivision. These modes are not very popular, so maybe they need to be promoted more.
Eighty Clicks offers a many different maps to play. Despite all this choice, the world map is by far the most popular one. 75% of all games are played on the world map. Let's zoom in and see which other maps are being played by the community:
The United States being the most popular world map is not a huge surprise. Most players are from the US and the states offer a wide variety of landscapes and settings. I have to admit I was surprised by the 2nd place: Australia. Even more interesting is that the majority of the Australian games are No Wander games. Apparently, getting stuck between spiders and kangaroos is something many players like to experience from behind the safety of their keyboard.

domain: geography


text:
The adverse reaction profile associated with immunosuppressive agents is often difficult to establish owing to the underlying disease and the concurrent use of multiple medicinal products.
The most commonly reported adverse reactions (occurring in >10% of patients) are tremor, renal impairment, hyperglycaemic conditions, diabetes mellitus, hyperkalaemia, infections, hypertension and insomnia.
Many of the adverse reactions stated as follows are reversible and/or respond to dose reduction. The frequency of adverse reactions is defined as follows: very common (≥ 1/10); common (≥ 1/100 to < 1/10); uncommon (≥ 1/1,000 to < 1/100); rare (≥ 1/10,000 to < 1/1,000); very rare (< 1/10,000), not known (cannot be estimated from the available data). Within each frequency grouping, undesirable effects are presented in order of decreasing seriousness.
Infections and infestations:
As is well known for other potent immunosuppressive agents, patients receiving tacrolimus are frequently at increased risk for infections (viral, bacterial, fungal, protozoal). The course of pre-existing infections may be aggravated. Both generalised and localised infections can occur.
Cases of BK virus associated nephropathy, as well as cases of JC virus associated progressive multifocal leukoencephalopathy (PML), have been reported in patients treated with immunosuppressants, including Advagraf.
Neoplasms benign, malignant and unspecified:
Patients receiving immunosuppressive therapy are at increased risk of developing malignancies. Benign as well as malignant neoplasms including EBV-associated lymphoproliferative disorders and skin malignancies have been reported in association with tacrolimus treatment.
Blood and lymphatic system disorders:
Common: anaemia, thrombocytopenia, leukopenia, red blood cell analyses abnormal, leukocytosis.
Uncommon: coagulopathies, pancytopenia, neutropenia, coagulation and bleeding analyses abnormal.
Rare: thrombotic thrombocytopenic purpura, hypoprothrombinaemia, thrombotic microangiopathy.
Not known: pure red cell aplasia, agranulocytosis, haemolytic anaemia.
Immune system disorders:
Allergic and anaphylactoid reactions have been observed in patients receiving tacrolimus (see Precautions).
Metabolism and nutrition disorders:
Very common: diabetes mellitus, hyperglycaemic conditions, hyperkalaemia.
Common: metabolic acidoses, other electrolyte abnormalities, hyponatraemia, fluid overload, hyperuricaemia, hypomagnesaemia, hypokalaemia, hypocalcaemia, appetite decreased, hypercholesterolaemia, hyperlipidaemia, hypertriglyceridaemia, hypophosphataemia.
Uncommon: dehydration, hypoglycaemia, hypoproteinaemia, hyperphosphataemia.
Very common: insomnia.
Common: confusion and disorientation, depression, anxiety symptoms, hallucination, mental disorders, depressed mood, mood disorders and disturbances, nightmare.
Uncommon: psychotic disorder.
Nervous system disorders:
Very common: headache, tremor.
Common: nervous system disorders, seizures, disturbances in consciousness, peripheral neuropathies, dizziness, paraesthesias and dysaesthesias, writing impaired.
Uncommon: encephalopathy, central nervous system haemorrhages and cerebrovascular accidents, coma, speech and language abnormalities, paralysis and paresis, amnesia.
Very rare: myasthenia.
Common: eye disorders, vision blurred, photophobia.
Not known: optic neuropathy.
Ear and labyrinth disorders:
Rare: deafness neurosensory.
Very rare: hearing impaired.
Common: ischaemic coronary artery disorders, tachycardia.
Uncommon: heart failures, ventricular arrhythmias and cardiac arrest, supraventricular arrhythmias, cardiomyopathies, ventricular hypertrophy, palpitations.
Rare: pericardial effusion.
Very rare: Torsades de Pointes.
Very common: hypertension.
Common: thromboembolic and ischaemic events, vascular hypotensive disorders, haemorrhage, peripheral vascular disorders.
Uncommon: venous thrombosis deep limb, shock, infarction.
Respiratory, thoracic and mediastinal disorders:
Common: parenchymal lung disorders, dyspnoea, pleural effusion, cough, pharyngitis, nasal congestion and inflammations.
Uncommon: respiratory failures, respiratory tract disorders, asthma.
Rare: acute respiratory distress syndrome.
Very common: diarrhoea, nausea.
Common: gastrointestinal signs and symptoms, vomiting, gastrointestinal and abdominal pains, gastrointestinal inflammatory conditions, gastrointestinal haemorrhages, gastrointestinal ulceration and perforation, ascites, stomatitis and ulceration, constipation, dyspeptic signs and symptoms, flatulence, bloating and distension, loose stools.
Uncommon: acute and chronic pancreatitis, ileus paralytic, gastrooesophageal reflux disease, impaired gastric emptying.
Rare: pancreatic pseudocyst, subileus.
Common: bile duct disorders, hepatocellular damage and hepatitis, cholestasis and jaundice.
Rare: venoocclusive liver disease, hepatitic artery thrombosis.
Very rare: hepatic failure.
Skin and subcutaneous tissue disorders:
Common: rash, pruritus, alopecias, acne, sweating increased.
Uncommon: dermatitis, photosensitivity.
Rare: toxic epidermal necrolysis (Lyell's syndrome).
Very rare: Stevens Johnson syndrome.
Musculoskeletal and connective tissue disorders:
Common: arthralgia, back pain, muscle spasms, pain in extremity.
Uncommon: joint disorders.
Rare: mobility decreased.
Renal and urinary disorders:
Very common: renal impairment.
Common: renal failure, renal failure acute, nephropathy toxic, renal tubular necrosis, urinary abnormalities, oliguria, bladder and urethral symptoms.
Uncommon: haemolytic uraemic syndrome, anuria.
Very rare: nephropathy, cystitis haemorrhagic.
Reproductive system and breast disorders:
Uncommon: dysmenorrhoea and uterine bleeding.
General disorders and administration site conditions:
Common: febrile disorders, pain and discomfort, asthenic conditions, oedema, body temperature perception disturbed.
Uncommon: influenza like illness, feeling jittery, feeling abnormal, multi-organ failure, chest pressure sensation, temperature intolerance.
Rare: fall, ulcer, chest tightness, thirst.
Very rare: fat tissue increased.
Not known: febrile neutropenia.
Very common: liver function tests abnormal.
Common: blood alkaline phosphatase increased, weight increased.
Uncommon: amylase increased, ECG investigations abnormal, heart rate and pulse investigations abnormal, weight decreased, blood lactate dehydrogenase increased.
Very rare: echocardiogram abnormal, electrocardiogram QT prolonged.
Injury, poisoning and procedural complications:
Common: primary graft dysfunction.
Medication errors, including inadvertent, unintentional or unsupervised substitution of immediate- or prolonged-release tacrolimus formulations, have been observed. A number of associated cases of transplant rejection have been reported (frequency cannot be estimated from available data).
Description of selected adverse reactions:
Pain in extremity has been described in a number of published case reports as part of Calcineurin-Inhibitor Induced Pain Syndrome (CIPS). This typically presents as a bilateral and symmetrical, severe, ascending pain in the lower extremities and may be associated with supra-therapeutic levels of tacrolimus. The syndrome may respond to tacrolimus dose reduction. In some cases, it was necessary to switch to alternative immunosuppression.

domain: literature


text:
Quick announcement first: A HUGE thank you to all of you who pre-ordered Awaken Your Genius. Thanks to your pre-orders, the book became a #1 new release on Amazon (more than two months before it’s even been published!).
We were inundated with pre-orders (in the best way possible!), and my team is still processing all the receipts. If you forgot to send in your receipt, please email it to [email protected] ASAP to get your bonuses.
Onto the regularly scheduled programming…
From time to time, instead of my usual email with one big idea you can read in 3 minutes or less, I share with you the best of what I’m reading, watching, and exploring. Enjoy!
BooksSmart Brevity: The Power of Saying More with Less by Jim VandeHei, Mike Allen and Roy Schwartz. From the description: “You’re wasting your reader’s time. Here’s how to change, in just six words: Brevity is confidence. Length is fear.” This book is a goldmine of insights on how to improve your communications—everything from emails to presentations—by cutting out the fluff. (Thank you to my friend and creative collaborator Chris West for gifting me a copy). Your Music and Your People: Creative and Considerate Fame by Derek Sivers. I’ll read anything that Derek writes. But this book sat unread on my shelf for a long time since I assumed it’d be useful for only musicians. I was completely wrong. If you’re a creator of any type trying to reach people with your work, this is a must read. Plus, it’s super short (and a masterclass of smart brevity at work). Mind Your Mindset: The Science That Shows Success Starts with Your Thinking by Michael Hyatt & Megan Hyatt Miller. From the endorsement I wrote for this great book, which was published this week: “The quality of our life is determined by the stories we tell ourselves. But instead of us shaping our stories, they end up shaping us. If you want to escape this trap—if you want to change your story and write a better one—this book is essential reading.”
I say very little about the plot of the films that follow—in large part because I don’t want to ruin the fun. I refuse to watch trailers—or even read film descriptions—because I want to be surprised from minute one.
The Banshees of Inisherin. (HBO Max) This is one of those rare films that stayed with me for a long time. It’s unpretentious and honest and hilarious and heartbreaking—and everything in between.
The Menu. (HBO Max) I loved this dark comedy. A deliciously original satire about fine dining and pretentious foodies.
Triangle of Sadness. (Amazon Prime | Apple TV) Another great dark comedy that pairs well with The Menu. This one is a satirical take on the uber rich and Insta-fame culture. Hilarious and over-the-top. (If you don’t have a strong stomach, skip this one).
Glass Onion. (Netflix) Hilarious sequel to Knives Out. A murder mystery that takes place on a Greek island. Simple and thoroughly entertaining.
The Bear. (Hulu) If you’re looking for a show you can watch to unwind from a stressful work day, this is NOT it. A chaotic yet beautiful show about a family sandwich shop in Chicago. Watching it feels like getting an anxiety-inducing hug. Brilliantly scripted and acted.
Music“Japan” by Tycho ft. Saint Sinner (Satin Jackets Remix). Everything about this song—from the vocals to the lyrics to the beat—is stunning. “Purple Hat” by Sofi Tukker. I dare you to resist dancing to this beat. I’ve found it impossible to not move while listening to it.