BBC Birmingham News Feeds
- Tony Pulis: West Brom boss says he 'will plough on' as manager after loss to Chelsea
- Maidstone United v Solihull Moors
- Walsall v Gillingham
- Liam Gallagher guitar stolen from blind woman in Birmingham
- Kwame Thomas: Coventry City loan striker to Solihull Moors
- Reading v Wolverhampton Wanderers
- John Motson meets BBC Radio 5 live's young commentator of the year
- Queens Park Rangers v Aston Villa
- Endris Mohammed trial: Dad guilty of murdering son and daughter
- Aston Villa: Jonathan Kodjia and Scott Hogan sidelined following international duty
BBC Bristol News Feed
- Wasteland in Bristol turned into a 'berry maze'
- Shanghai Masters: Ronnie O'Sullivan hammers Judd Trump in final
- Bristol Rovers v AFC Wimbledon
- Wales v Georgia: Travel warning to rugby fans in Cardiff
- Elderly woman injured by suspected shoplifter in Bristol
- Shanghai Masters: Ronnie O'Sullivan to face Judd Trump in China final
- Sheffield Wednesday v Bristol City
- Bath University vice-chancellor told to 'move on' at staff event
- Premiership: London Irish v Bath
- Joe Morrell: Midfielder signs new contract with Bristol City until 2019
Cornwall Council News feed
- Forestry and strengthening community networks on the agenda for Falmouth and Penryn Community Network Panel meeting
- Cornwall’s Lord Lieutenant presents British Empire Medals to five Local Community Heroes
- Two Cornwall Council social workers nominated for prestigious awards
- Cornwall Council continues to work with partners to repair road and support residents and businesses in Coverack
- Cornwall Council announces road into Coverack expected to open next week
- Cornwall one of the lowest areas in England for new HIV diagnosis
- How would you allocate the budget for Council services? Public consultation opens today
- Treffry Viaduct and Luxulyan Valley set for major conservation works following a £3.6M National Lottery boost
- Cabinet discusses key decisions on budget, investment programme, new waste contract and proposals to transform adult and children’s services
- Pencalenick students 'pass out' at Falmouth Community Fire Station parade
BBC Essex News Feed
- Colchester United 0-0 Morecambe
- Portsmouth 1-0 Southend United
- Shanghai Masters: Ronnie O'Sullivan beats Judd Trump for 'one of the best victories'
- Children in Need: Fundraisers in the east support Pudsey
- BBC Children in Need Pudsey pump trolley challenge
- Colchester woman jailed for spending parents' life savings
- Shanghai Masters: Ronnie O'Sullivan to face Judd Trump in China final
- Design for planned nuclear power plant in Essex unveiled
- Greater Anglia's new trains revealed in virtual reality
- 'Break-in victim' died at Braintree Police Station
BBC Hampshire News Feed
- Eastleigh v Barrow
- Hartlepool United v Aldershot Town
- Portsmouth v Southend United
- Ross Stearn: Sutton United re-sign winger after Eastleigh release
- Boy, 13, 'sexually assaulted by stranger' in Aldershot
- Children in Need money getting kids ready for school
- Children in Need: Special needs pre-school grateful for support
- Liverpool v Southampton
- Glitter banned by Dorset children's nursery chain
- Simon Heslop: Eastleigh sign York City midfielder on month's loan
BBC Manchester News Feeds
- John Stones: Man City defender set for six-week injury lay-off
- Bury 0-3 Blackburn Rovers
- Wigan Athletic 1-2 Bradford City
- Oldham Athletic 3-1 Rochdale
- Macclesfield Town 0-0 Boreham Wood
- Andy Burnham launches plan for 'left-behind' town centres
- Man arrested after light aircraft crash in Salford
- Phil Jones: Jose Mourinho says defender had six injections to play for England
- Peter Kay's Car Share to make surprise return
- Megan Campbell: Manchester City Women defender suffers serious knee injury
BBC Lincolnshire News Feed
- Lincoln City 1-2 Coventry City
- Children in Need 2017 highlights
- X Factor singer Ella Henderson's father loses fraud convictions appeal
- Bridge backed over 'misused' Lincoln level crossing
- Man charged with raping two girls in Derby in 1970s and 1980s
- Price of Football 2017: League Two ticket prices rise
- Price of Football 2017: Young adult fans are 'put off' by cost of football
- Contaminated mustard gas soil to go from Roughton Moor
- Brexit 'not a disaster' for Grimsby, says Norman Lamont
- Hundreds support Lincoln street appeal for Beechey brothers
Amersham News Views and Information News Feed
- Hearing Dogs Christmas Market – Saturday 25th and Sunday 26th November
- Drawing for Beginners: Still-Life and Animal Studies – Amersham – 29 Nov & 6 Dec
- Amersham & Chesham Bois Choral Society Concert – Amersham – 25 November
- Live Stand Up Comedy at the Mad Squirrel Tap & Bottle Shop – Amersham – 22 November
- Live Stand Up Comedy at the Mad Squirrel Tap & Bottle Shop – Amersham – 8 November
- Amersham Museum New Dinky Toy Exhibition
- The Titfield Thunderbolt – 8 to 11 Nov. @ The Elgiva Theatre, Chesham – Chesham Theatre Company
- 2nd Amersham Common Scouts Jumble Sale – 28 November
- Sir Christèmas: A Selection of Seasonal Music – 3 December
- Amersham Art Group – Oil Painting Demonstration – 7 November
A project between education staff and the Benefits Team at Northumberland County Council has brought over £500,000 of pupil premium funding into the county.
The Alnwick and Amble Community Alcohol Partnership (CAP), led by Northumberland County Council, is holding a range of activities throughout Alcohol Awareness Week, highlighting the dangers associated with alcohol.
A new timetable has been laid out for preparation of the Northumberland Local Plan - the key planning policies for the county up to 2036.
Community health experts are raising awareness of the need for regular testing as part of national HIV testing week which starts on November 18.
Hundreds of residents have had their say on Morpeth’s future - with the county council now encouraging other towns to come forward.
Northumberland County Council is leading the way in tenancy fraud awareness in the region, following the establishment of the North East Tenancy Fraud Forum (NE-TFF) earlier this year.
Partners from across Northumberland along with Councillors gathered on Tuesday (7th November) at an alcohol and drug forum organised by Northumberland County Council.
A fire has broken out at Sanders Plant And Waste Management site on Butterwell Drive in Pegswood, near Morpeth.
Morpeth residents can still have their say on how the town develops over the next few years - by taking part in an online survey.
A project just completed in Cramlington is set to improve parking issues and alleviate traffic congestion at peak times near Shanklea Primary School.
Members of the public joined staff, Northumberland County Councillors and ex servicemen for a Remembrance Day Service at County Hall in Morpeth earlier today ( Friday November 10.)
Police and partners have hailed the latest 12 Streets initiative for Blyth as a big success.
Communities in Northumberland are being encouraged to take the lead on developing affordable homes in their area.
Hexham town centre is to get extra pre-Christmas parking when new spaces are opened up this week.
Councillors and Northumbria Healthcare NHS Foundation Trust have come together to feed local insights into the plans to build a new healthcare facility in Berwick.
Alnwick Community Centre was a buzz with the launch of new project led by Northumberland County Council.
At a Cabinet meeting on Tuesday (7 November) Northumberland County Council approved funding for a new school on land of the former fire station.
As the county heads into winter, the council’s cutting-edge fleet of salt spreaders are back on the region’s roads.
A special wedding fair is to be held in Hexham next weekend , providing the perfect opportunity for couples planning their big day, to meet local wedding suppliers and find everything they need for their perfect day, all under one roof.
Firefighters across Northumberland were faced with a steady stream of Bonfire Night call-outs on their busiest night of the year.


text:
High yielding tomato, a consistant garden performer. Widely adapted, thrives and produces well in nearly any climate. Large, 1 pound meaty, flavorful fruits are excellent for slicing or garnishing summer dishes. Indeterminate habit. Stake or cage for best production. Disease resistant: VFN.
NOTICE: Please note that not all products are available all the time. The color and size can vary from photographs.
Prices listed, if any, are subject to change without notice.

domain: agronomy


text:
Several years ago, Maureen Pratt earned her Master of Fine Arts in Theater Arts/Playwriting from UCLA's School of Theater, FIlm and Television. She expected to be writing scripts. God had other plans.
A few years after her graduation, Maureen was diagnosed with a life-threatening case of organ-involved lupus. Her life turned upside down as she grappled with the effects of the illness and other health conditions that ensued. She was no stranger to serious health challenges; even as a child, Maureen had survived numerous bouts of pneumonia, flu, and other infections. But lupus made her take a fresh look at her life goals - and took herlifelong, strong Catholic Christian faith and writing in a direction she'd never imagined.
Today, Maureen writes and speaks about walking with the Lord while living with chronic pain and illness. Her most recent book is "Don't Panic!: How to Keep Going When the Going Gets Tough (Franciscan Media). She is also the author of, "Peace in the Storm: Meditations on Chronic Pain & Illness" (Image Books/Randomhouse), "Beyond Pain: Job, Jesus, and Joy" (Twenty-Third Publications), "The First Year: Hypothyroidism, Second Edition" (Perseus) and "Taking Charge of Lupus: How to Manage the Disease and Make the Most of Your LIfe." She writes the syndicated column, "Living Well," for Catholic News Service, and has also written for Saint Anthony Messenger Magazine, Journey for Women Magazine, The Upper Room Magazine, LupusNow, and Arthritis Today. Maureen's health continues to be a challenge, however she feels honored to be able to bring her perspective, from experience and knowledge, to others.
"Good Days...Bad Days with Maureen Pratt" is a new way for Maureen to reach people who carry the burden of illness and pain in their lives, or who care for someone who does. Through the blog, she hopes to bring issues of health, wellness, and spirit into focus and, especially, inspire others that, no matter what health challenges, illness, or hardships they endure, each person can find a good way to realize the wonderful potential God has placed within each heart and soul.
Politics, weather changes, back-to-school/work/life in general…Patience? It might seem as if this season of external stresses that’s pressing upon our internal resilience will never end. But, blessedly, it will. And if we apply patience to these next few days, we’ll […]
I have lived with multiple, serious chronic illnesses for many years. I am also a life-long Chicago Cubs fan. The two don’t necessarily have much to do with each other, however this week and, I hope, the following couple of […]
Whether I am out or at home, going through a medical test or waiting for a prescription, I pray. I might recite a prayer that I’ve memorized, or I might just carry on a more free-form conversation with God. But […]
How wonderful it is to have faith! Despite the stresses in the world and the way some denigrate those who believe, persecuting people because they turn to Jesus, my faith in the Lord is the light that makes all the […]
My heart goes out to all who had to weather (no pun intended) Hurricane Matthew. From Haiti to Cuba to the U.S. East Coast, it was terrifying to watch the monster storm move and it must have been even more […]
What’s your idea of a good walk? One that takes you through your neighborhood, visiting with friends along the way? A rapid-paced, perspiration-inducing bit of exercise around a track? A great accomplishment on a “bad day”: less pain from chair […]
I have a simple, silver and pearl ring that I like to wear. But for several weeks, I couldn’t find it. I looked and looked, and thought and thought about where I’d last worn it, but no amount of looking […]
Sometimes when we are at a low point, or we have experienced unfeeling, unthinking hurt from someone who doesn’t understand the pain or chronic illness we struggle with, we might wish that someone could speak up for us, defend us, […]
Many years ago, when I lived near our Nation’s capital, I had emerged from a polling place on Election Day and a busload of foreign journalists piled out of it. They were covering the current Presidential election, a heated race […]
I’m still thinking of the amazing creature that turned up at the bottom of the ocean off the coast of California. If you haven’t seen it, here’s the link: http://nautiluslive.org/video/2016/08/12/googly-eyed-stubby-squid The poor purple, stubby squid must have been terrifed at the sudden […]

domain: literature


Work on the new engines actually began late last year and the first prototype V8 “will fire up in July”. According to unidentified sources, it will generate around 550 to 570 horsepower and target Ferrari's V8.
The decision by Lotus to abandon Toyota engines and gain unique powertrain expertise stems from a survey of 10,000 Internet users carried out during the Paris Motor Show last fall.
The manufacturer also wants to derive a four-cylinder engine from the new V8 but will call on Toyota once again if the results don't prove satisfying.
Source : Autocar


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- Author: Meera Varman, MD; Chief Editor: Russell W Steele, MD more...
In this article, pediatric mucormycosis will be reviewed, such as infection involving immunosuppressed children; this disease has also been observed in neonates (especially premature infants), patients with burns, and children with a history of incidental trauma.
Mucormycosis usually refers to fungal infections in immunosuppressed hosts caused by ubiquitous molds found in organic matter and soil. Such molds belong to the order Mucorales.[1, 2, 3] The infections they cause manifest in the rhinocerebral, pulmonary, cutaneous (see the image below), gastrointestinal (GI), disseminated, and central nervous systems.
Mucormycosis is often life threatening. Therefore, prompt diagnosis and institution of antifungal therapy are vital, as is appropriate management of the underlying disease process.
The fungus of mucormycosis gains entry into the body through the nasopharynx. It can be inhaled into the lungs, or it can extend to the sinuses, orbit, and brain. The occurrence of mucormycosis depends on host immunity, but the mechanisms of increased susceptibility in certain hosts remain perplexing. Regardless of the anatomic site involved, characteristic histopathologic findings include angioinvasion with subsequent tissue infarction and necrosis leading to tissue destruction.
The fungal pathogens that cause mucormycosis belong to the class Zygomycetes and the order Mucorales. Rhizopus species are the agents most commonly isolated in mucormycosis, followed by Rhizomucor species, Absidia corymbifera, Apophysomyces elegans, Cunninghamella bertholletiae, Mucor species, and Saksenaea vasiformis.[1, 2, 3]
Risk factors for mucormycosis in adults and children include diabetes mellitus (especially with ketoacidosis), which is the underlying condition most commonly associated with this disease. This feature is probably due to diminished function of phagocytes at low pH.
Other individuals at risk include patients with malignancy, those with protein-calorie malnutrition, those with skin breakdown due to burns, those with trauma or who are undergoing surgery, those with acute and chronic renal disease, and those with hematologic disease who are receiving deferoxamine.
Patients with immunosuppression due to acquired immunodeficiency syndrome (AIDS), organ transplantation, neutropenia, or steroid therapy are also at risk.
Hospital-acquired mucormycosis has been reported. In a review of 26 hospitalized, posttraumatic patients with mucormycosis, approximately 57% were females and two thirds had comorbidities (ie, diabetes mellitus, leukemia, immunosuppression); diabetes was noted in 6 patients. In hospitalized patients with cannula, wound or occlusive dressings should be closely watched for erythema or necrosis.
Neonatal infection and prematurity
Neonates, especially those born prematurely, can be at risk. Unusual incidents of neonatal mucormycosis might have occurred when patients were exposed to contaminated surfaces, such as bandages, tongue depressors used as arm splints, or cardiac-monitor leads.
In the United States, mucormycosis is most common in immunocompromised hosts, although cases in immunocompetent patients are also reported. Underlying diseases, such as diabetes mellitus and malignancy, are risk factors. Environmental spore exposure (from exposure to construction activity) has also led to clinical cases of mucormycosis. Other cases have been reported in patients with traumatic skin injury (eg, associated with the use of nonsterile adhesive tape or with use of tongue depressors as splints in neonates). Exposure to voriconazole, which is not active against mucormycosis, is noted to be a risk factor in patients with cancer.
No racial or sexual predilection is reported.However, most cases of mucormycosis occur in immunosuppressed adults. In a pooled review, Kline described 41 cases of rhinocerebral mucormycosis occurring in children and adolescents aged 2 months to 18 years. About 49% of cases were found in patients with diabetes mellitus, and 15% of cases were found in those with leukemia. Four of the 41 children (10%) had no predisposing conditions.
Survival rates largely depend on early diagnosis and treatment of mucormycosis as well as resolution of the patient's underlying condition. If the disease progresses and if the underlying condition remains uncontrolled, death usually ensues. The overall mortality rate in adults is 50%, though survival rates higher than this have been reported.
In neonates, these invasive fungal infections can be rapidly fatal; the time from clinical symptoms to death is in the range of 6 to 42 days.
Because the disease is rare and because therapy is not standardized, no studies aid in predicting patient outcomes.
Richardson M, Koukila-Kahkola P, Shankland G. Rhizopus, Rhizomucor, Absidia, and other agents of systemic and subcutaneous zygomycoses. Murray PR, Baron EJ, Jorgensen JH, Pfaller MA , Yolken RH, eds. Manual of Clinical Microbiology. 9th ed. Washington, DC: American Society of Microbiology; 2007.
Sugar A. Agents of mucormycosis and related species. Mandell GL, Bennet JE, Dolin R, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 7th ed. Philadelphia, Pa: Churchill Livingstone; 2009. Chapter 259.
Wiedermann BL. Zygomycosis. Feigen RD, Cherry JD, Demmler-Harrison GJ, Kaplan SL, eds. Textbook of Pediatric Infectious Diseases. 6th ed. Philadelphia, Pa: Saunders; 2009.
Frater JL, Hall GS, Procop GW. Histologic features of zygomycosis: emphasis on perineural invasion and fungal morphology. Arch Pathol Lab Med. 2001 Mar. 125(3):375-8. [Medline].
Simbli M, Hakim F, Koudieh M, Tleyjeh IM. Nosocomial post-traumatic cutaneous mucormycosis: a systematic review. Scand J Infect Dis. 2008. 40(6-7):577-82. [Medline].
Robertson AF, Joshi VV, Ellison DA, Cedars JC. Zygomycosis in neonates. Pediatr Infect Dis J. 1997 Aug. 16(8):812-5. [Medline].
Kline MW. Mucormycosis in children: review of the literature and report of cases. Pediatr Infect Dis. 1985 Nov-Dec. 4(6):672-6. [Medline].
Garbino J, Myers C, Ambrosioni J, Gumy-Pause F. Report of a successful treatment of pulmonary Cunninghamella bertholletiae infection with liposomal amphotericin and posaconazole in a child with GvHD and review of the literature. J Pediatr Hematol Oncol. 2010 Mar. 32(2):85-7. [Medline].
Rüping MJ, Heinz WJ, Kindo AJ, Rickerts V, Lass-Flörl C, Beisel C, et al. Forty-one recent cases of invasive zygomycosis from a global clinical registry. J Antimicrob Chemother. 2010 Feb. 65(2):296-302. [Medline].
Dave SP, Vivero RJ, Roy S. Facial cutaneous mucormycosis in a full-term infant. Arch Otolaryngol Head Neck Surg. 2008 Feb. 134(2):206-9. [Medline].
Scheinfeld N. A review of the new antifungals: posaconazole, micafungin, and anidulafungin. J Drugs Dermatol. 2007 Dec. 6(12):1249-51. [Medline].
Ullmann AJ, Lipton JH, Vesole DH, Chandrasekar P, Langston A, Tarantolo SR, et al. Posaconazole or fluconazole for prophylaxis in severe graft-versus-host disease. N Engl J Med. 2007 Jan 25. 356(4):335-47. [Medline].
Garg PK, Gupta N, Gautam V, Hadke NS. Gastric zygomycosis: unusual cause of gastric perforation in an immunocompetent patient. South Med J. 2008 Apr. 101(4):449-50. [Medline].
Goel S, Carter JE, Culpepper M, Kahn AG. Primary renal zygomycotic infarction mimicking renal neoplasia in an immunocompetent patient. Am J Med Sci. 2009 Oct. 338(4):330-3. [Medline].
Kontoyiannis DP, Lionakis MS, Lewis RE, Chamilos G, Healy M, Perego C, et al. Zygomycosis in a tertiary-care cancer center in the era of Aspergillus-active antifungal therapy: a case-control observational study of 27 recent cases. J Infect Dis. 2005 Apr 15. 191(8):1350-60. [Medline].
Singh N, Aguado JM, Bonatti H, Forrest G, Gupta KL, Safdar N, et al. Zygomycosis in solid organ transplant recipients: a prospective, matched case-control study to assess risks for disease and outcome. J Infect Dis. 2009 Sep 15. 200(6):1002-11. [Medline].

domain: biology


text:
Lyle Weldon was inspired to spend a career telling stories on film while sitting in a movie theater watching Steven Spielberg’s “Close Encounters of the Third Kind.” A chance meeting with Mr. Spielberg while Lyle was a film student at California State University, Northridge lead to this sage piece of advice from the filmmaker: “Learn how to write a movie before you film it. Until you can tell a story really well on paper, save your money. Film will wait.” Taking that to the extreme, Lyle has since written for multiple Emmy-winning primetime television series as well as both live action and animated children’s series. But it’s the silver screen which continues to inspire Lyle’s deepest dreams. While several of his screenplays have been optioned and he’s been hired to rewrite others, he still looks forward to seeing one of his own films in a movie theater. He’s excited to join the talented crew at Aisle Seat Books and welcomes the opportunity to share his stories with avid readers before film audiences have the chance. He lives in Los Angeles with his beautiful wife and their two equally-lovely daughters.
Where to find Lyle Weldon online
Where to buy in print
This member has not published any books.

domain: entertainment


A number of unions have called on the Algerian Ministry of Education to cancel the decision to dismiss teachers who went on strike, Ennahar Online reported yesterday.
In a joint statement signed by several bodies, the groups expressed their anger with Minister of education Nouria Benghabrit-Remaoun’s decision to dismiss the teachers.
The bloc, which includes five syndicates, said that the Benghabrit-Remaoun’s move “is a flagrant violation of law”.
Meanwhile, the boc expressed its “unlimited support” for the dismissed teachers, noting that it will launch a series of protests on 10 March that will last until the teachers are returned to their posts.
Hundreds of teachers have been on strike for several weeks over better pay and conditions, amid public spending cuts caused by falling energy prices.


The Alien Defender vehicle is a four-wheeled, all-terrain light gun platform. It is armed with a rotating gun turret on the back which uses the new ADU ray gun and flick-fire missiles on either side. Details include pistols behind the front wheels to simulate suspension, and a round ridged "column" brick on the back to act as an engine grille. The single driver is unarmed. The front of the vehicle show an alien ship being targeted and shows the two flick-fire missiles from before. Alien Hoverbike:
The set also includes a small space hover-bike with two lasers piloted by an Alien Pilot.
Jump on the scout vehicle to catch that alien invader!
The alien defense unit soldier is patrolling the city in his swift scout vehicle when an alien invader whizzes by on his spaced-out mini hover bike. Nab the invader with the scout vehicle’s rotating anti-UFO laser and 2 flick missiles! He won’t make it past the fully armed alien defense unit this time.
Includes 2 minifigures: alien defense unit soldier and alien trooper
Features 2 vehicles: mini hover bike and scout vehicle
Scout vehicle features anti-UFO laser and 2 flick missiles
Rotate the anti-UFO laser!
Fire the flick missiles at the attackers!
Scout vehicle measures 4” (10cm) long and 3” (7cm) tall


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And we're off! My very full fashion week schedule kicked off this morning at the red carpet for the Heart Truth Red Dress collection, an incredible runway show that raises awareness for heart disease while putting some very famous faces into very chic dresses. Check out my photos (and find out how the stars get glam!) after the jump...
The Heart Truth pulled together an A-list cast of women to model in the show, including Jennie Garth and Tori Spelling (a 90210 reunion of my very own!), Amanda Bynes, Daisy Fuentes, Katie Couric, Hilary Duff, Vivica A. Fox and Kristi Yamaguchi. Olympic gymnast Nastia Liukin was the first one to walk the red carpet, wearing a cute little red dress by Max Azria. "I just shot the Max Azria campaign in L.A., and they asked me which dress from the shoot was my favorite. I loved this one, it was like a seafoam green, and they made it for me in red!"
Vivica A. Fox also worked the red carpet in a sparkling dress by Jenny Packham and my absolute favorite shoes of the day. "They're Dior, darling," she told me. "And I love them." So do I! What do you guys think? Would you wear them?
Olympic swimmer Amanda Beard modeled a dress from one of my favorite new design duos, Cushnie et Ochs. "I'm really a jeans and hoodie kind of girl, so this is so much fun for me," she told me. "I love to get all glammed up like this and get my hair and makeup done and be all girly."
Hilary Duff was also there, wearing Donna Karan and spilling all of her style secrets to Suze. Check back later for more from those two!
Whose red dress look do you guys like best? Which one would you wear? And are you as excited as I am to see so many big names getting involved in such an important cause?
Need to catch up on your fashion week Ps and Qs before things really get underway? Get Susan and my crash course in Fashion Week Etiquette 101 right here!

domain: celebrity


text:
The word ‘quattro’, chosen by Audi for its pioneering high-performance four-wheel-drive cars, immediately captures glamour and excitement in the minds of all motorsport enthusiasts.
This book, written by a leading journalist and quattro devotee, explores 24 years of factory-prepared and factory-supported quattros in motorsport, from 1980 to 2004.
It is a tale that extends from rough rally stages to race tracks, from pine-fringed ice trails in the depths of European winters to the shimmering heat haze and melting asphalt of Texas street racing.
Along the way, it explains how quattros collected four world rally championships, five American driver/manufacturer crowns and a single-year haul of seven international touring car titles, plus numerous other honours.
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Please, contact us for information on the state of conservation and the selling price of this product.

domain: library


Current Position and Past Experience
Ben Pingel is currently a scholarly assistant professor at Washington State University. He is also Creative Director of DesignWire. Prior, he was an assistant professor of multimedia communication at Wesley College. He was also an online learning coordinator and communication faculty at Brigham Young University.
Education, Honors and Achievements
Pingel will soon complete a Doctor of Philosophy in Communication from Regent University. He also earned a Masters in Communication and Leadership from Gonzaga University and a Bachelor of Arts in Communication from Brigham Young University.
Personal Details and Community Involvement
When he is not exploring national parks or playing games with his family, Pingel enjoys photography, biking, playing piano, and racquetball.
You can connect with Ben on LinkedIn


text:
© 2023 MJH Life Sciences™ and dvm360 | Veterinary News, Veterinarian Insights, Medicine, Pet Care. All rights reserved.
Equine fluid therapy--not just lactated ringer's solution (Proceedings)
Administration of fluids to horses with various disease processes is one of the foundations of treatment for equine practitioners.
Administration of fluids to horses with various disease processes is one of the foundations of treatment for equine practitioners. While sterile isotonic fluids such as Lactated Ringers Solution (LRS) are commonly used to rehydrated horses, a variety of other fluid formulations and supplements are available for horses.
Total body water
The clinician should have a general knowledge of the distribution of water within the body when contemplating fluid needs. The estimated total body water (TBW) in the adult horse is 60-70% of the body weight corresponding to approximately 300 liters in the 500 kg horse. The TBW can be further divided into intracellular fluid (ICF; 40% of body weight) and extracellular fluid (ECF; 30% of body weight). The ECF compartment is further divided into transcellular fluid (CSF, pleural, peritoneal, synovial, GI), interstitial fluid and plasma. Based on the 500 kg horse, this corresponds to approximately 200 L of intracellular fluid and 100 L of extracellular fluid (30-35 L of plasma; 50-75 L of interstitial fluid/lymph; 30-50 L of transcellular fluid).
Determination of fluid requirements
While assessment of TBW through sodium dilution or multi-frequency bioelectrical impedance analysis in horses may provide a more accurate evaluation of total body water and ECF and ICF volume, these methods are currently impractical for clinical use. Thus, veterinarians commonly use various physical exam findings to estimate the hydration status of the horse.
This may include observation of mentation and temperature of extremities, pulse quality, capillary refill time, mucous membrane color, heart rate and skin tent. While these observations may indeed loosely correlate with hydration status, one must remember that many of these findings are subjective and can be altered by various causes.
More objective parameters that can be used to evaluate the hydration status of the horse include measurement of the packed cell volume and total protein (PCV/TP), urine specific gravity, serum lactate trends, central venous pressure, blood pressure and trends in body weight, although many of these may be altered by various disease processes as well. The clinician is encouraged to monitor trends in these objective measurements to better estimate the hydration status of the patient as well as evaluate the response to fluid therapy.
Crystalloids are fluids containing small molecular weight molecules, such as electrolytes or glucose, which readily cross the capillary membranes. Replacement fluids are isotonic compared to the ECF and mimic the composition of the plasma and ECF and include preparations such as LRS, Normosol-R, and Plasmalyte-R; maintenance fluids are hypotonic compared to the ECF and contain less sodium and potassium then replacement fluids. They include preparations such as Normosol-M and Plasmalyte 56.
Continuous administration of IV fluids is commonly implemented in the hospital situation but may be more difficult in the field setting. The amount of fluid necessary to reverse hypovolemia is variable, depending on the severity. However, in the hypovolemic adult horse, 20-80 mL/kg (10-40L in a 500 kg horse) as an IV bolus should be considered initially. Subsequently, re-evaluation of patient hydration should be performed, based on the subjective and objective parameters discussed above, and the fluid plan should be adjusted as necessary.
Commonly, replacement fluids, such as LRS, are used for resuscitation as an IV bolus which rapidly replaces fluid deficits in the hypovolemic horse; however, after replacement of acute deficits, the remainder of the bolus can cause a transient state of hypervolemia to which the body responds by renal elimination. In addition, only a portion (30-50%) of crystalloids that are administered as a bolus remain within the vascular space 30 minutes after administration, with a large percentage quickly redistributed to the ECF. Thus, bolus administration of crystalloids is important in the rapid restoration of fluid deficits but may not be ideal therapy for sustained fluid losses.
Due to the time involved in administering large volumes of IV fluids (30-40L) some clinicians may choose to administer solutions, such as hypertonic saline (3-4 mL/kg) or hetastarch (5-10 mL/kg), which rapidly expand the intravascular compartment. However, all of the above fluid replacement techniques require administration of a continuous infusion of IV fluids at a minimum goal of meeting the standard maintenance dose of 60-75 mL/kg/day (30 L/day for 500 kg horse), adding more to compensate for ongoing losses (i.e. diarrhea) if necessary. In the field setting, the clinician may be left with only bolus therapy as an option. However, periods of hypovolemia may occur if enough time elapses between bolus doses. Reliance on lay horse-owners to administer continuous fluids is controversial and left to the attending veterinarian.
Oral Fluids, administered via NG tube, are a cost effective method of supplementing fluid intake in certain situations where the intestinal tract is able to absorb fluids. In horses that are moderately to severely hypovolemic, IV administration of fluids should be considered rather than oral fluids. As well, horses with severe enterocolitis may not have the functional capacity to completely absorb orally administered fluids. The administration of pure water has been documented to be of minimal benefit in restoring plasma volume in horses exercised in hot and humid conditions.1,2 Therefore, if at all possible, oral fluids with electrolytes should be administered.
One formulation for an isotonic solution consists of 4.9 grams/liter of table salt (NaCl) and 4.9 grams/liter of lite salt (KCl) which yields a concentration of 123 mEq/L of sodium, 157 mEq/L of chloride and 34 mEq/L of potassium.1,2 This can be estimated by 15 mLs each of table salt and lite salt in 4 liters of water. In a 500 kg horse, the veterinarian can administer 5-6 liters of oral fluids at a time, as often as every 30 minutes. Evaluation of gastric reflux should be performed prior to subsequent administration of additional oral fluids. Some horses may demonstrate signs of colic with oral fluid administration; if this occurs, the volume should be decreased or an alternate route of fluid supplementation should be selected.
Electrolyte Supplementation is readily available for most electrolytes and is often times necessary to correct specific deficiencies. Because the horse's diet typically contains large amounts of K+ and Ca++, horses that have decreased appetite or are anorexic will continue to excrete K+ (via kidneys) and have less Ca++ absorption from the gut. In addition, most crystalloid fluids have little K+ and Ca++, thus horses on IV fluids can develop hypokalemia and hypocalcemia, unless further supplementation is implemented. Rechecking of electrolytes is important when supplementation is used because gauging the amount necessary to compensate for deficits can be difficult.
· Sodium – Serum sodium in a healthy adult horse is in the range of 135-140 mEq/L. Most commercially available isotonic fluid solutions contain sodium to replace or maintain this concentration. However, if a patient has a serum sodium concentration of < 125 mEq/L, additional sodium supplementation should be considered. If sodium is < 110 mEq/L, neurologic signs may develop and sodium correction needs to be accomplished carefully. A general formula that can be estimate the sodium deficit is as follows: Na+ required = (Desired Na+ – Patient Na+) x 0.6 x BWT (kg). For example, if the patient weighs 50kg and the serum sodium is 110 and you want to raise it to 125 you would need to add approximately 450 mEq of sodium to the fluid plan (125-110 x 0.6 x 50 kg). Sodium can be supplemented IV via solutions such as 7.2% hypertonic saline (1232 mEq/L) or orally via table salt (1 gram = 17 mEq Na+ & Cl-)
· Potassium – Potassium is primarily an intracellular cation with serum concentrations in health ranging from 3.5-4.5 mEq/L. The most common formulation available for IV supplementation is potassium chloride (KCl) containing 2 mEq/mL of K+. Potassium can be safely administered at a rate of 0.5 mEq/kg/hr; commonly, 20-40 mEq of KCL is added per liter of fluids. Oral supplementation of lite salt provides 13 mEq of K+ per gram of salt.
· Calcium – Total calcium is divided into ionized (55%; free-form), protein bound (45%) and complexed with anions (5%) with the ionized form being the best gauge for the need for supplementation. Ionized calcium concentrations less than 3.6 mg/dL (0.9 mmol/L) may require additional calcium. Different methods of calcium supplementation exist but for those who like exact calculations, the following formula can be used as a guide to estimate calcium deficits:
o Ca++ deficit=(6.5-Ca++)(10)(0.3)(BWT[kg])/Ca++ratio where the Ca++ ratio=iCa++/total Calcium
o Example: 450 kg horse w/Ca++ of 4.5 mg/dL and total Calcium of 10 mg/dL
§ (6.5-4.5)(10)(0.3)(450) = 6000 mg Calcium
23% Calcium Gluconate contains 21.4 mg/mL of elemental calcium. Other methods of calcium supplementation include adding 250-500 mLs of 23% calcium gluconate to 10 liters of fluids and then rechecking the calcium status. Avoid combining calcium with bicarbonate as they may react.
· Sodium Bicarbonate – In general, one should consider using sodium bicarbonate in cases of metabolic acidosis in which the HCO3 is < 15 mEq/L and the pH is < 7.25. Often, rehydration and electrolyte correction will allow correction of acid-base status, negating bicarbonate supplementation. The formula to calculate bicarbonate supplementation is: HCO3 deficit = BWT(kg) x base deficit x 0.4. Sodium bicarbonate can be administered at various concentrations including 1.3% (0.156 mEq/mL), 5% (0.6 mEq/mL) and 8.4% (1 mEq/mL). Oral supplementation is also an inexpensive method of replacement with 1 gram of salt (baking soda) containing 12 mEq of NaHCO3.
· Magnesium & Phosphorus – Mg and Phosphorus are often overlooked electrolytes that may be deficient in various equine diseases. Magnesium sulfate can be administered at a rate of 2-8 mg/kg, IV whereas Phosphorus can be administered at an IV rate of 0.01-0.03 mmol/kg/hr.
Colloids are fluids that contain large sugar or protein molecules that are unable to cross the capillary membranes and therefore persist within the vascular space for longer periods when compared to crystalloids. These larger molecules exert osmotic pressure and consequently draw fluid into the vascular space. Because of this trait, colloids are excellent choices for resuscitation (require shorter infusion times and less volume) or treatment of hypoproteinemic patients. The most readily available colloids include 6% hetastarch, human albumin, and equine plasma.
Hetastarch is the most commonly utilized synthetic colloid used in horses and contains modified branch-chain glucose polymers of amylopectin; these molecules are slowly metabolized by α-amylase prior to renal excretion and uptake by the reticulendothelial system. The COP of 6% hetastarch is 30-33 mmHg and is typically administered at a dose of 10 mL/kg. In one experimental study, hetastarch (10 mL/kg) increased the COP from 24 to 27 mmHg in healthy ponies for at least 120 hours whereas the duration of action was only 24-36 hours in hypoproteinemic horses and foals.
Hetastarch (~$50/500 mLs) may be more cost effective when compared to equine plasma (~$125/1000 mLs) and is easily stored and readily available. However, refractometry (total protein) does not account for the oncotic contribution of synthetic colloids and therefore, COP must be monitored (normal COP adult horse: 20-27 mmHg; foal: 17-21 mmHg). A side effect of hetastarch is decreased circulating von Willebrand's factor (vWF) and factor VIII activity at higher (i.e. 20 mL/kg) doses potentially resulting in coagulopathies.
Albumin (5 or 25%) has numerous functions including maintenance of intravascular COP, serving as a buffer for anions and cations and as a transport protein for medications and hormones, among other duties. Albumin accounts for approximately 80% of the plasma COP and also has a negative charge that attracts cations such as sodium to which water follows (Gibbs-Donnan effect). 30-40% of albumin is located in the intravascular space whereas the remainder is within the extravascular compartment.
There is a slow flux of albumin between these two pools. In situations of severe hypoproteinemia, administration of human albumin should be considered. On a small equine report, administration of 25% human albumin raised the COP in hypoproteinemic horses from 9.7 to 16.6 mmHg as compared to an increase in COP of 11.4 to 13.3 mmHg when Hetastarch was administered. No large studies exploring the use of human albumin in horses has been published but anecdotal evidence supports its use in certain circumstances.
Frozen equine plasma is readily available through a number of commercial sources and has the benefit of not only providing albumin and contributing to increased COP, but also has other valuable serum proteins such as immunoglobulins, fibronectin, antithrombin and clotting factors. The COP of plasma is approximately 20-25 mmHg. Plasma should be administered through a blood administration/filter set and patients should be monitored for transfusion reactions that would include pyrexia, tachycardia, tachypnea, muscle tremors, urticarial or signs of colic.
Marlin DJ et al. Rehydration following exercise: effects of administration of water versus an isotonice oral rehydration solution (ORS). Vet J 1998;156:41-49.
Sosa Leon LA et al. The effects of tonicity, glucose concentration and temperature of an oral rehydration solution on its absorption and elimination. Equine Vet J 1995;Suppl(20):140-146.
Jones PA et al. Effect of hydroyethyl starch infusion on colloid oncotic pressure in hypoproteinemic horses. JAVMA 2001:218:1130-5.
Jones PA et al. Oncotoic, hemodilutional, and hemostatic effects of isotonic saline and hydroxyethyl starch solution in clinically normal ponies. Am J Vet Res 1997;58:541-8.
Dewitt SF. Proceedings 22nd Annual ACVIM Convention, 2004.


CH& Partner Donald Marcy’s Pro Bono Aid Leads to Win for Seattle Center Resident Organizations
CH& Partner Donald Marcy provided pro bono aid to Seattle Center, resulting in a win for Seattle Center’s resident organizations. His work was vital for convincing Sound Transit to move their proposed light-rail station away from KEXP, Seattle Rep, and other arts organizations. Among other benefits, this change prevents noise disruptions, preserves space for bands to access the venues, and protects trees planted for the World’s Fair. Learn more here.


British clarinettist Matthew Scott graduated with a 1st Class honours degree from the Royal Academy of Music in 2013, followed by an MA with Distinction and DipRAM in 2015. He was generously supported by The Countess of Munster Musical Trust and The Greenbank Scholarship in his Postgraduate studies.
Daniel King–Smith studied at the Royal Academy of Music under Piers Lane and Michael Dusseck, where he received the Harold Craxton Chamber Music Prize and the Max Pirani Piano Trio Prize.
Poulenc Sonata for clarinet and piano
Horovitz Sonatina for clarinet and piano
Weinberg Sonata for clarinet and piano, Op 28
Prokofiev Sonata in D major, Op 94
Debussy Première Rhapsody
Chabod Variations on the Nutcracker Ballet


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The Quality Inn of Reading features a free continental breakfast buffet, free high-speed Internet service, warmly appointed guest rooms, and friendly service. The hotel is located just 1 mile from the Reading Regional Airport, and is convenient to Read...
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Unless otherwise provided in the articles of incorporation or bylaws, written notice stating the place, day and hour of the meeting and, in case of a special meeting, the purpose or purposes for which the meeting is called, shall be delivered not less than 10 nor more than 50 days before the date of the meeting, either personally or by mail, by or at the direction of the president, or the secretary, or the officers or persons calling the meeting, to each member entitled to vote at the meeting. If mailed, the notice shall be considered to be delivered when deposited in the United States mail addressed to the member at the member's address as it appears on the records of the corporation, with postage prepaid.
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October 27, 2010
Interactive Music Videos?
Like a Choose Your Own Adventure book? I’m in!
Andy Grammer, a new pop artist on the scene, has teamed up with Vevo, S-Curve Records (his label), and Interlude technology to come up with a user-interactive music video, with which an internet-goer can play and choose which scene will come next. In the video, “Keep Your Head Up,” there are several options that can be played multiple times to get different results.
Though fans will most likely already be drawn to this video because of its interesting nature, Vevo also made a smart move to get Rainn Wilson (Dwight Schrute in “The Office”) to make a cameo appearance in the music video. Well done, marketing team!
This music video comes very soon after Arcade Fire tried their luck with HTML5 technology in one of their music videos, allowing users to see images and videos of their hometowns (or whatever town they enter in the prompt) during the music video.
What do you think of the Choose Your Own Adventure music video??
Posted by Shaane at 7:00 am


Americans take down approximately $50 billion in pay day loans a 12 months, each accumulating a huge selection of bucks in charges and interest. But a tiny and growing solution that enables its users to just take an advance on the paycheck may be providing the cash advance industry a run for the money.
San Francisco-based economic technology business also made headlines later a year ago whenever Walmart, the country’s largest personal boss, announced it might begin providing also’s solution included in its employee benefits package. Along with supplying tools that allow workers to trace their investing and conserve money, Even features Instapay, makes it possible for users to advance a few of their next paycheck as much as 13 times before payday.
As the user that is even making use of his / her currently accumulated hours, also does not charge the employee interest regarding the advance.
Also is certainly one of a small number of technology businesses have actually popped up in the last few years wanting to get wages to workers faster as well as on need. Organizations like FlexWage Options and Instant Financial offer on-demand pay, but those solutions in many cases are associated with a debit card released because of the business in place of an worker’s main banking account.
Even founder Jon Schlossberg has stated publicly that the main organization’s objective would be to put the pay day loan industry away from business, claiming it exploits the economically vulnerable. He shared usage that is internal solely using the Associated Press that displays, at the least preliminarily, that Even users are less likely to want to touch the cash advance market after they subscribe to the business’s solutions.
“You’ve got this industry that is entire of organizations benefiting from People in the us struggling to call home paycheck to paycheck, and payday lenders are actually probably the most predatory,” Schlossberg stated.
Payday lenders say they give you a required solution, with several People in the us not able to show up with money to pay for an urgent emergency that is financial. Additionally they state they provide to your nation’s most hopeless, that are usually the risk that is highest for perhaps not trying to repay the mortgage. But experts state the prices and costs are excessive and will trap the debtor in a period of financial obligation that will last months. The customer Financial Protection Bureau, underneath the Obama administration, ended up being attempting to control the lending that is payday nationwide, but underneath the Trump management the bureau has started the entire process of reversing those laws.
Even’s data show that roughly 28 % of the users took down an online payday loan when you look at the full months before registering for the solution. Four months after becoming a member of also, that figure drops to not as much as 20 per cent. Also calculated the figure by learning use behavior of their users from 2017 until September 2018 december.
Also has the capacity to inform which users are nevertheless utilizing pay day loans because Also users connect their bank reports towards the application. The business will be capable tell what kinds of deals a individual is making, and whether they bear the traits of the cash advance transaction or name a payday loan provider because the other celebration.
Schlossberg admits that also could possibly be lacking some pay day loan transactions, specially people in which a check is employed in the place of an immediate debit from the debtor’s account.
The info can also be restricted to the truth that Walmart, undoubtedly its customer that is biggest, just started utilizing the product on December 15, 2017.
Schlossberg stated the business is dealing with scholastic scientists in the efficacy of Even’s Instapay product versus cash advance usage, with all the aim of publishing sometime in 2019.
Walmart could be the only business that publicly states it makes use of also, but a much spokesman states this has “more than” 10 organizations registered currently, with 400,000 active members. Also does fee Walmart workers a $6 month-to-month charge to utilize its premium features, including Instapay.
Customer advocates, that have very long targeted the payday lending industry, stated these were happy to see options to payday advances available but urged caution about their usage.
“The decrease is intriguing and possibly promising but too quickly to draw any conclusions,” stated Scott Astrada, manager of federal advocacy during the Duncan payday loans Center that is left-leaning for Lending.
В© 2018 The Associated Press. All legal rights reserved.


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Thursday Workshop Roar For Matriarchy
Thursday, February 15, 2018 - 18:30
This year, RAG has tapped into a huge and growing interest in matriarchal societies. Did matriarchy ever exist? More importantly, can our beautiful planet be rescued from patriarchy and restored to some kind of gender-egalitarian rule? Tonight's meeting will be given over to planning for an International Women's Day event. Beyond that, we will be thinking of Donald Trump's scheduled visit in October, organizing to give him the Matriarchal welcome he deserves... Steve Bannon has issued a dire warning to US President Donald Trump: "The anti-patriarchy movement is going to dramatically alter the power structure across the world. I think it's going to unfold like the tea party, only bigger," the former White House chief strategist told Bloomberg News. "It's not Me Too. It's not just sexual harassment. It's an anti-patriarchy movement." He added: "Time's up on 10,000 years of recorded history. This is coming. Women are gonna take over. This is real." OK sisters, let's bring it on.
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Ethnographers of Congo Basin hunter-gatherers have emphasised ritual as a levelling mechanism that sustains egalitarianism by strengthening community spirit and mediating power evenly between individuals and subgroups. My talk will discuss how both mythology and ritual are involved in mutual causal interactions with other factors of social life that mark the emergence of inequality among a small community of Baka former hunter-gatherers. An emerging ideology of male predominance in mythology mirrors the same phenomenon in ritual, kinship practices and household economics. I argue that this preoccupation with patriarchal concerns in mythology is one of several strands of evidence pointing to the centrality of gender politics in the emergence of inequality among the Baka.

domain: sociology