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The timeless singer/songwriter plays a new song at the City Winery of New York.
'Harry Potter and the Cursed Child' star Alex Price explains what makes the play so special and important.
The incredibly talented musician Steve Onotera aka Samuraiguitarist dressed up his thumbs as individual members of Guns N’ Roses who showed their “faces” during their respective parts in an amazing four-track cover of their classic song “Sweet Child O’ Mine“. Thumbs up Samurai! The original version of the song and the band. Follow Laughing Squid […]
When I was a child I used to spend lazy Sunday mornings with my parents, relaxing in our large den on adjoining plush, comfy couches. My dad would turn the stereo on to listen to whatever opera or classical music was playing on WQXR....Show More Summary
Who doesn't like putting together a troupe of talking animals to enact dramatic or comedic plays for a moody King who is constantly changing his mind like an excitable child that has been told he can only buy one toy in the entire store?...Show More Summary
When it comes to raising children, most of the focus is on mothers. But a growing body of research shows that fathers play an essential, if often undervalued role in a child’s development.
A new trailer for the upcoming sci-fi horror/thriller Morgan has been released and this one focuses on establishing the title character as an innocent, playful, and curious child before growing up into a murderous aberration of genetic manipulation. That may have come off a bit more harsh than intended… In the film from producer Ridley […]
In the recent hit game Inside, you play a child on the run through a mysterious and horrifying surveillance state straight out of 1984. Oxenfree stars a group of teenagers with a complicated history arriving at a spooky island for an ill-advised camping trip. Show More Summary
Kylie Jenner is arguably stepping up as Tyga's now longtime GF and helping him raise his child... the other scenario -- she's pissing off baby mama Blac Chyna something fierce. Kylie took 3-year-old King Tuesday to play a round of miniature…
The 217-square-foot house has a space-efficient layout that fits all the amenities of a regular-sized home. The sitting area lies above a small room that can be used as a guest room or play area for a small child. A small, operable window ensures the crawlspace is well ventilated. Show More Summary
Last time (I think), you have been warned. There are absolutely, definitely huge spoilers in this post for JK Rowling’s The Cursed Child. Look away if you don’t want the play ruined. I mean it. This is your last warning… Okay, coast is clear. So Voldemort and Bellatrix had a child: Delphi, otherwise known as […]
As a child, Dolly Parton wanted nothing more than to look like "the town trollop." She admired the woman's makeup and hair and tight clothes. Now, Parton is playing a version of that woman, a "painted lady," in the sequel to the NBC special Coat of Many Colors. ... More »
Have you ever heard the saying ‘The streets is watching’, well in new Antonio Cromartie’s case, ‘The Courts were watching’. Just one day after signing a one-year deal to play for the Indianapolis Colts this upcoming season, an arrest warrant was issued for his arrest for not paying child support. Not wanting to go […]
Melissa Gilbert, who played Laura Ingalls Wilder on the “Little House On The Prairie” TV show as a child and who launched a congressional bid last year, won’t be working under a big rotunda anytime soon. On Monday, an election board in Michigan approved the removal of Gilbert’s name from ballots. Show More Summary
I saw her games as a distraction that pulled her away from me—until I learned the value of play. “Slow down! Will you please just slow down?” my wife snaps, her fingers spread wide like a small child about to have a meltdown. I look in the rear-view mirror to make sure no one will plow into us. Show More Summary
Having a child with allergies means always being on guard - looking at nutrition labels, avoiding certain outdoor (or indoor) areas, and denying play dates at houses with pets. Having a child with a severe allergy just got even moreShow More Summary
Ben Affleck and his 10-year-old daughter Violet pose for a photo backstage with the cast of the play Harry Potter and the Cursed Child over the weekend in London, England. The 44-year-old actor wasn’t the only star in the audience at that performance. He was joined by his Suicide Squad co-star Margot Robbie, as well [...]
An official report in the Disney alligator death of 2-year-old Lane Graves was released on Monday. The toddler was killed while playing near shallow water on a beach resort in Orlando. The unsuspecting child was snatched by an alligator lurking by the shoreline on June 14 around 8:30 p.m. Show More Summary
Halle Berry plays a mothers worst nightmare in “Kidnap.” What Mother wouldn’t go to any length to save her child? Halle Berry is about to play a role that will… The post Halle Berry plays a mothers worst nightmare in “Kidnap.” See the...Show More Summary
Halle Berry plays a mom who will go to any length to get her child back in the trailer for her upcoming movie Kidnap. The Oscar-winning actress is seen having a fun time at a park with her son and then witnesses him getting taken by a kidnapper. She then stops at nothing to get [...]


Some sort of advert looking for church volunteers…
Some sort of advert looking for church volunteers…
Are you still looking for an idea for your Easter services this year?
Are you wanting something particularly dramatic?
Have you got plenty of spare (hopefully) fake blood?
How about something like this?
Personally I would like to see plenty of screaming and assorted noises from Jesus – Just as the guy preaching is trying to make a serious point.
Found over at Christian Nightmares.
Worth watching until the end…
Have you ever received a Facebook notification reminding nudging you to wish Happy Birthday to a deceased friend? It’s an odd experience, almost as if the internet is nudging you to hang out with an old friend. It’s almost, because any interaction is strictly one way.
What if interaction could feel like its two way, and you almost feel like you could see the one you lost?
The below video tells the story of one guys experience playing a computer game against his dead Dads previous best, and at the same time, giving what could be the best reason to play computer games.
The voice over is pulled directly from a YouTube comment that was under a video called, “Can Video Games Be a Spiritual Experience?” Could the above be described as a spiritual experience?
I sometimes wonder what technology would look like in 20 – 30 years time. If people can have experiences like the above with what would now be consider old technology, what does the future hold?
In fact, is (what we might consider) a future technology already happening?
I read a theory a few months ago, that you could argue that human beings are separated into two separate states. One is our physical bodies. The other is our identities, or our souls.
Most (if not all) religions have a concept of an afterlife. A place where the soul lives on, but what if our earthly identity could be captured?
Eternime is one example of a company with plans to help your digital identity live on. They plan to combine everything you put on social media, photos from smart phone, email, and so on – the aim being to create a digital version of yourself, that will be accessible after you die.
According to the BBC website:
“Depending on the facts it has collected, the avatar will be able to offer anything from basic biographical data to being an engaging conversational partner,” says Marius Ursache, Eternime’s founder.
It is set to launch next year, and according to Eternime, more than 37,000 people have already signed up for the service.
Its not just a service like Eternime where this is possible, there is also Facebook.
I don’t know about you, but I’m not sure how I feel about this.
On one hand, I’m not going to be around for ever. Could there be some comfort in having a “digital dad” available online after I’m gone? But what if the service fails? Wouldn’t that be some sort of “second death”? In fact, at the time of writing this on The Church Sofa, the Eterni.me website is down with the error message: “The server is temporarily unable to service your request due to maintenance downtime or capacity problems. Please try again later.”
Doesn’t the idea of a “second death” sound creepy?
Does the whole thing sound a little creepy? People I’ve spoken to have commented on how weird it sounds. Is weird, because it sounds unnatural? And is it so unnatural, that we’re in danger of not just playing God, but going full blown Black Mirror?
If this new Black Mirror future, is in fact now, how would this impact the church and its teaching? Particularly how we communicate about the afterlife? Somewhere between Heaven and Hell, is there a place for a digital limbo dependent on service contracts?
(A version of this post first appeared on The Dads Sofa)
Try and read what you’re sending to people.
Unless you want your communication to be screenshot and sent over Facebook, which, could be an interesting evangelism strategy.
Anyone want to try it?
Struggling to make it to Church this week?
Play this video and close your eyes.
Let the sound of this guy transport you to Church…
Have you ever struggled to get yourself to church on time? If you have children, you’ll know that the struggle to get children AND adults to church on time, has its own challenges*. Now admittedly we only have Little Sofa, so perhaps this speaks of our own organisation, but I figured it would be interesting to note down our typical timeline of events before we leave for church on a Sunday morning.
The minutes before we need to leave, are in bold…
65 minutes : Everyone goes to get clothes on.
60 minutes: Little Sofa successfully lobbies for a bath.
55 : Upon being told that bath is ready, Little Sofa proceeds to play statues.
50 : Little Sofa is put into the bath.
30 : Negotiations begin over who washes whose hair.
20: Hair washed. Little Sofa thrown into clothes.
15: Negotiations over different clothing begin.
10: Daddy challenges Little Sofa over who can get ready first. Little Sofa shouts “Me!”
9 minutes, 50 seconds. : Daddy checks twitter.
9 minutes, 49 seconds : Little Sofa declares that she is ready, and yes. Indeed. She also has shoes on.
8 minutes : Daddy falls downstairs, he finds Little Sofa was joking and is in fact just finishing getting clothes on.
5 minutes : The Game Of Statues restarts.
3 minutes: There is a shout “I’m already! I got my shoes on before you!”. She is in fact, next to the front door, with shoes on. Where as, Daddy doesn’t have shoes on. Or socks for that matter.
Time to go!!!!: There is a shout of “Can I bring all my babies” *proceeds to go upstairs to bring, all her babies**
5 minutes late : ALL THE BABIES ARE IN THE CAR. Once the car is parked up, there is a request of… “I want to bring all the babies… they might cry if I leave them in the car!”
Negotiations begin over which babies should stay in the car.
*Obviously some families manage to get everyone of their huge family to church on time. Every weekend. Fresh faced, and smiling. These people are obviously on a heavenly fast track, as examples of pure Godly organisation.
** Dolls. Not babies. I repeat. They are really dolls. Lots and lots of dolls.
Speaking in Tongues.


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Kiel, 18. August 2014
"Harvard scientist David Keith on why, despite the risks, we must investigate shooting particles of sulphate into the stratosphere, to combat climate change."
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domain: news


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A startup that spun out of Cambridge College claims a battery breakthrough that may cost an electrical automobile in simply six minutes.
It’s one thing we heard earlier than, however the distinction right here is that they declare that they’ll commercialize the brand new battery as quickly as subsequent 12 months.
The startup, Echion Applied sciences, was based by Dr. Jean De La Verpilliere whereas he was learning for his PhD in nanoscience on the College of Cambridge.
De La Verpilliere claims to have created a brand new powder that replaces graphite inside Li-ion battery cells and improves recharge capability in a powerful means.
He instructed Cambridge Independent:
The powders are the central element of a lithium battery. This can be a new form of powder that lets you recharge in six minutes, not 45 minutes. This features a automobile, so your electrical automobile is sort of as simple to cost as it’s to refuel conventionally.
The startup claims to have a prototype that has been validated, and it secured investments from Newable Personal Investing and Cambridge Enterprise.
De La Verpilliere stated:
We’re engaged on strategies to make powders which might be scaleable and the place 1,000 tonnes might be made fairly simply in factories. We now have a prototype now, and are shifting towards commercialization early subsequent 12 months. The assessments need to be validated beforehand.
It’s uncommon that startups can persuade battery makers to make use of their chemistry of their costly manufacturing traces, however Echion claims that its new materials can simply be included into current manufacturing.
The corporate wrote on its web site:
Echion Applied sciences gives a novel platform for battery materials and composite manufacture at pilot scales. Our supplies then merely ‘drop in’ to current battery manufacturing infrastructure with no capital value. This gives a low barrier to market entry and speedy buyer entry for our battery supplies.
Echion Applied sciences claims to be working with OEM, and they’re aiming for manufacturing to start out in 2020.
Claims of battery breakthroughs are so interesting: It’s the concept a few scientists are creating a brand new materials that ends in a a major enchancment in battery capability and accelerates electrical car adoption.
Nonetheless, we heard it many occasions earlier than, and it hardly ever if ever really ends in a industrial product.
Echion Applied sciences appears to have a concentrate on commercialization, which is encouraging, however I’d take it with a grain of salt since there’s not a lot details about the precise materials.
It’s nonetheless vital to comply with potential battery breakthroughs, however I prefer to remind everybody that breakthroughs usually are not required to allow electrical automobiles to be aggressive with gasoline vehicles. These applied sciences will come and push EVs ahead, however within the meantime, present incremental enhancements on li-ion batteries are sufficient to make EVs extremely aggressive.
Subscribe to Electrek on YouTube for exclusive videos and subscribe to the podcast.

domain: chemistry


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Ian Rapoport of NFL Media reports that the Jaguars are set to kick off interviews with head coaching candidates starting Thursday with former Eagles HC Doug Pederson.
Pederson is one of eight candidates who currently have interviews scheduled:
- Buccaneers OC Byron Leftwich (Requested)
- Buccaneers DC Todd Bowles (Requested)
- Cowboys OC Kellen Moore (Requested)
- Cowboys DC Dan Quinn (Requested)
- Former Eagles HC Doug Pederson (Scheduled)
- Colts DC Matt Eberflus (Requested)
- Packers OC Nathaniel Hackett (Requested)
- Former Lions HC Jim Caldwell (Scheduled)
Head Coach Candidates
- Bills DC Leslie Frazier
- Jaguars interim HC Darrell Bevell
Pederson, 53, began his NFL coaching career with the Eagles as a quality control coach in 2009. He worked his way up to QB coach before following Andy Reid to Kansas City and becoming the Chiefs’ offensive coordinator in 2013.
The Eagles hired Pederson as head coach in 2016. They later signed him to an extension through 2022 heading into the 2018 season, only to fire him after 2020.
Pederson led the Eagles to a record of 42-37-1 (53.1 percent) over the course of five seasons. This includes a Super Bowl championship in 2017.


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This post is also available in: Italiano (Italian)
A real treat for the palate! Soft, delicate and delicious, these gluten free soft baked donuts will make your breakfast special.
A glass of warm milk, a cup of steaming hot coffee, the first morning lights and a breakfast that tastes like home. What more can you wish for? In the morning, for me, breakfast is a simple pleasure, made even more intimate and comforting by sharing. When I prepare these gluten free soft baked donuts, nobody really cares that they are gluten free, because they are so soft and tasty that they really make everyone happy.
You will need:
- 170g of gluten free all purpose flour
- 170ml of whipping cream
- 140g of sugar
- 2 eggs
- 10g of baking powder
- A tsp of vanilla extract
Whip the eggs with the sugar and vanilla extract until you get a frothy and pale mixture. Then, pour the cream as you continue whipping.
Also add the sifted flour together with the baking powder and gently incorporate with a spatula.. In this case I used the gluten free all purpose flour blend by Schar, which I find very versatile and suitable for both sweet and savory. You can use your favourite all purpose flour as well.
Let’s bake our gluten free soft baked donuts!
Transfer the mixture to a donut pan, previously buttered and floured . Fill in for about 2/3, considering that they will rise while baking. Bake in a preheated oven at 180°C for about 15/20. Do not let the top become too golden brown because these soft gluten-free donuts will be served … upside down!
Make sure the donuts have completely cooled down before gently removing them from the pan: help yourself with a flexible spatula or even a toothpick. Then, reverse them and decorate them with plenty of icing sugar. You can also dip them in a chocolate ganache if you feel really fancy!

domain: food


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Are you tired of downloading Android games that are poorly made and lack engaging gameplay? Don’t worry; we’ve got you covered. In this post, we’ll outline the top 12 features that every good Android game should have. From graphics and sound to gameplay and user interface, these features are critical for a great gaming experience.
There are over 500,000 games that can be played on Android, but some of them are not worth your time. Therefore, some of the best Android games comes with fantastic features which we have listed below.
- Engaging Gameplay
The gameplay is the most crucial aspect of any Android game. Players should feel a sense of accomplishment and reward when playing the game, which keeps them engaged and motivated to continue playing. A good Android game should have well-designed levels, challenges, and objectives that are both challenging and fun to play. It should also provide players with different gameplay modes, such as a story mode or an endless mode, to provide variety and keep the gameplay fresh. Minecraft is a good example of a game with engaging gameplay.
- Intuitive User Interface
The user interface (UI) is the visual and interactive component of the game that allows players to navigate and interact with the game. A good Android game should have an intuitive UI that is easy to navigate, even for new players. The UI should be visually appealing, with clear icons and instructions that guide players through the game. Players should be able to understand the UI and interact with the game’s elements easily.
- Stunning Graphics
Graphics are a significant component of any Android game, and they play a crucial role in immersing players in the game world. A good Android game should have stunning graphics that are visually appealing, with high-quality textures, smooth animations, and realistic effects. The graphics should be optimized for different screen sizes and resolutions, ensuring that players have a consistent and enjoyable experience regardless of their device.
- High-Quality Sound
Sound effects and background music are essential elements of the gaming experience, providing players with auditory feedback and creating an immersive atmosphere. A good Android game should have high-quality sound that is synchronized with the gameplay, with sound effects that match the action on-screen and background music that enhances the mood and atmosphere of the game.
- Regular Updates
A good Android game should receive regular updates that fix bugs, improve performance, and add new features and content to keep players engaged. Regular updates show that the developers are invested in the game’s success and are committed to making the game the best it can be. Players appreciate updates that add new content and features, keeping the game fresh and exciting.
- Multiplayer Support
Multiplayer support is a popular feature for many Android games, allowing players to compete or collaborate with other players from around the world. A good Android game should have robust multiplayer support, providing players with a fun and competitive experience. Multiplayer support can be achieved through online play, where players compete against each other in real-time, or through local play, where players can compete against each other on the same device.
- Offline Play
Many players prefer to play Android games offline, so it’s important that a good Android game can be played without an internet connection. Offline play ensures that players can enjoy the game even when they are not connected to the internet, such as when they are traveling or in areas with poor internet connectivity.
- In-Game Purchases
In-game purchases are a popular way for players to enhance their gaming experience by unlocking new levels, characters, or items. However, it’s important that in-game purchases are not essential to the core gameplay and do not create an unfair advantage for paying players. In-game purchases should be optional and provide players with a way to support the developers while enjoying additional content.
- Social Media Integration
Social media integration allows players to share their progress, achievements, and high scores with their friends and followers, increasing the social aspect of the game. A good Android game should have robust social media integration, allowing players to share their achievements on social media platforms such as Facebook, Twitter, and Instagram.
- Customization Options
Customization options allow players to personalize their gaming experience by changing the game’s settings, characters, or items to suit their preferences. A good Android game should provide players with a variety of customization options, such as different skins or color schemes, allowing players to tailor the game to their liking.
- Replay Value
Replay value is the amount of enjoyment a player can get from playing a game multiple times. A good Android game should have high replay value, providing players with different challenges and objectives each time they play. This can be achieved through randomly generated levels, different difficulty modes, or new game modes that unlock as the player progresses through the game.
- Compatibility with Different
Devices Compatibility with different devices is essential for a good Android game, as players use a variety of devices with different screen sizes and resolutions. A good Android game should be optimized for different devices, ensuring that players have a consistent and enjoyable experience regardless of their device. The game should be compatible with both high-end and low-end devices, ensuring that a wide range of players can enjoy the game.
In conclusion, a good Android game should have engaging gameplay, an intuitive user interface, stunning graphics, high-quality sound, regular updates, multiplayer support, offline play, in-game purchases, social media integration, customization options, compatibility with different devices, and low battery consumption. By incorporating these 12 features into your Android game, you can create a truly exceptional gaming experience that will keep players engaged and coming back for more.

domain: entertainment


The total crowd at Melbourne Park on the first day of the Australian Open hit 17,922, including day and night sessions in three divided zones.
It was well down on the 64,387 fans that crammed onto the grounds on the opening day of last year's championship but way more than any other grand slam held since then.
The state government is allowing up to 30,000 people per day into Melbourne Park for the Australian Open, which is less than 50% of capacity.
The precautions are in place to provide some social distancing because of the COVID-19 pandemic.
There were no fans allowed at the US Open, only about 1,000 per day were allowed at Roland Garros and Wimbledon was cancelled.


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Farmerphile no. 14 is back from the printer and available for order. As a not-so-gentle reminder, this issue features a sample excerpt from the novel The Evil in Pemberley House (featuring Doc Savage's (Wildman's) daughter, Patricia Wildman, as well as a magnificent illustration of the Doc Wildman coat of arms, based on Phil Farmer's research and description.
I will have several copies of issue 14 for sale on consignment through Who Else Books, at the dealer's room at MileHiCon 40 in Denver, where I'll be spending most of my weekend. Also available on consignment will be copies of Myths for the Modern Age: Philip José Farmer's Wold Newton Universe, Tarzan Alive, Tales of the Shadowmen vols. 1-4, and Lance Star--Sky Ranger, as well as two full sets of all 14 issues of Farmerphile (in addition to the extra copies of no. 14 mentioned above).
I know this blog post is probably not reaching many locals, but just in case... hope to see you there!

domain: literature


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Pembroke power station construction team receives award for outstanding health and safety
Visit our media section and follow the link "Press contacts"
The Alstom-led team that built the 2160 MW Pembroke gas-fired power station for RWE has been recognised for its outstanding health and safety work during the construction process.
The team received the National and Joint Council for the Engineering Construction Industry (NJC) Award for Health and Safety in Engineering Construction, the first time it has been given since July 2011.
The judging committee highlighted that the project was genuinely outstanding in its engagement with safety representatives, and that there was a genuine appetite among senior managers to get out onto the site in order to fully understand what was really going on at the operational workface.
Steve Burgin, Vice President of Sales for Northern and Central Europe for Alstom, said: Its fantastic to get this sort of recognition from a respected industry body like the NJC, and its made even more special that this is the first time the award has been given in almost two years. That shows that its a hard award to win, but we were able to show that our teamwork with RWE, our contractors, the workforce, and the local community led to a strong culture and, ultimately, a great safety record.
Simon Jameson, RWE Project Director for UK New Build CCGT, said: Its great to be recognised for what was such a successful project. It really was a case of everyone working together from the management teams to the project teams to the guys on the ground, and that gave us good communications and great collaboration from day one.
Brendan Stack, from the GMB, said: Recognition from the NJC is greatly appreciated. Working safely is the number one priority for the industry, and transparency and openness were the keys to the success of the Pembroke project, especially the health and safety aspects. The structure from the beginning was right, with senior stewards playing an important role in building respect between the workforce and the project management team.
Jock Simpson, Executive Chairman of the NJC, said: The engineering construction industry is difficult and can be dangerous. Safety must be our first consideration, and the NJC Award celebrates where clients, contractors and the workforce work together exceptionally well at managing safety. The award, which is only given to companies who excel in safety in the engineering construction industry has not been awarded since July 2011.
Pembroke is the largest gas-fired power station in the UK and consists of five generating units that can produce enough for the electricity needs of around three million homes. The power station was officially opened in September 2012.
Tel +44 (0)1788 545602 or +44 (0)7801 775650


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LANSING -- Lawmakers and Gov. Jennifer Granholm said Thursday night they were still working on a deal to avoid a partial government shutdown next week, but the specter of a shutdown still hovered over the talks.
Granholm said in a five-minute televised address that played on TV and radio stations around the state Thursday evening that she was taking the first steps toward shutting the government down, but remained hopeful an agreement could yet be reached Thursday night.
"Productive negotiations are now under way in my office that could head off this government shutdown while there's still time. We have made significant progress in the last 48 hours. We've narrowed our differences," she said from her ceremonial office in the state Capitol.
She warned, however, that she would not back extending the current budget into the fiscal year that starts Monday and said lawmakers needed to pass a mix of cuts, tax increases and government reforms in the next few hours.
Senate Majority Leader Mike Bishop, the lead Republican in budget negotiations, said during his televised address from a Capitol hallway that Granholm didn't need to bring the state to the brink of a shutdown.
"This is a defining moment in our state's history," he said, urging the governor to do more than just continue government policies of the past. "It is your responsibility to take the right action. We demand it," he told her.
For the complete story, go to Mlive's NewsFlash here.


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My place is close to Northfield Mount Hermon School, The Gill Tavern, The Farm Table & Kringle Candle, Crumpin Fox Golf Course. You’ll love my place because of the ambiance, privacy, the setting & the view.. My place is good for couples, solo adventurers, and business travelers. In accordance with CDC guidelines we now disinfect. For guests who intend to work from home here or who like to stream, - we just upgraded our WiFi Extender to Tri-Band - giving super-fast speeds up to 2.2Gbps
Cozy, vintage, eclectic, artsy cottage in the heart of thriving village in beautiful Western Mass. Central, yet quiet, relaxed, and comfortable. Lush gardens. Just minutes to outdoor water and hiking recreation, Old Deerfield Village, Bridge of Flowers. One hour to Mass MOCA, two to Boston, Three to NYC. Private Room is small but comfortable with double bed, desk, book case, closet. Guests have shared use of cottage kitchen, living room, bath gardens. More information
Located on the shore of Tully Pond, The Writers Retreat is a newly designed 325sqft lake side cottage with breathtaking views of Tully Mountain. This 4-season cottage is built with salvaged barn wood; up-cycled maple floors and custom built furniture and lighting. It's the little sister to The Fishing Cottage. You'll find this intimate home has everything you need to relax, write the next Great American Novel, connect with a lover, or just plain chill. Note: landscaping is a work-in-progress.

domain: travel


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WITH Bluesfest kicking off in two days, the who's who of the music business are rolling into the Northern Rivers.
19th April 2011 2:04 AM
THE countdown is on for Bluefest 2011, with only four nights left before an estimated 45,000 people flock to Byron for the...
18th April 2011 8:04 AM
THREE projects, embarrassing displays of affection and an interview that made Ben Harper adjust his attitude. Brighter...
17th April 2011 3:04 PM
BYRON Bay Bluesfest organisers have revealed the line-up for the sixth day of the 22nd annual festival.
01st Feb. 2011 10:02 AM


UN Secretary General Antonio Guterres strongly condemned the “appalling attack” on Monday at Kabul University in Afghanistan, stressing that the incident is an assault on the human right to education.
The Secretary-General expressed his deepest sympathies to the families of the victims and wished a speedy recovery to those injured.
“This appalling attack, the second in ten days on a school facility in Kabul, is also an assault on the human right to education,” a statement issued by the spokesperson for the Secretary-General said.
Guterres reiterated that those responsible must be held accountable. “The United Nations stands by the people and Government of Afghanistan in support of their long-held aspirations for peace,” the statement said.
Prime Minister Narendra Modi also strongly condemned the attack, asserting that India will continue to support Afghanistan’s brave struggle against terrorism.
“Our prayers are with the families of the victims and the injured,” Modi tweeted. “We will continue to support Afghanistan’s brave struggle against terrorism,” he said.


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The designs for the medals to be awarded at the 2019 Pacific Games in Samoa have been released.
Each medal, gold, silver and bronze, has a flower graphic, incorporating Samoan stylised images of tava’esina - a native breed of bird - and fish.
The Pacific Games logo is on the front, with the Government of Samoa crest on the back.
It uses parts of the same design that can be seen on the clock tower of the Samoan capital of Apia, as well as on street banners throughout Upolu, at the airport arrivals hall and on Savai'i ferries.
All the medals will be handed out from wooden presentation trays hand-carved by local artisans.
"The medals incorporate traditional Samoan designs, that are used throughout our Games imagery and branding," Samoa 2019 director of branding and communications Klaus Stunzner said.
"Medallists from around the Pacific will be departing our country with a token of our culture that we hope they are proud of."
A commemorative medal was also released, which will be given to every participant at the Games - athletes, officials and volunteers - to mark the occasion.
Just over 2,300 medals will be awarded, with open water swimming being the first medal event on July 8, and the final day (July 20) having seven medal events in athletics, basketball 3x3, football, netball, touch, triathlon and volleyball.
In total, there will be 323 individual medal ceremonies, while about 5,000 athletes from 24 countries will be competing in 27 sports at venues throughout Apia in the Games due to open on July 7.

domain: design


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June 17, 2021
Eden’s offices are closed tomorrow in observation of Juneteenth. Saturday is the official day that marks the oldest holiday celebrating the end of slavery in the United States.
Dating back to 1865, it was on June 19 that the Union soldiers, led by Major General Gordon Granger, landed at Galveston, Texas with news that the war had ended and that the enslaved were now free. Note that this was two and a half years after President Lincoln’s Emancipation Proclamation – which had become official January 1, 1863. There are several versions of what caused the delay, regardless, the June 19 date was celebrated with parties, food, and celebrations. The tradition faded during the Great Depression but saw a revival in interest during the Civil Rights era. More recently, President Joe Biden made the date an official national holiday.
We encourage you to join us as we mark this date and stay tuned to learn more about Eden’s commitment to ending anti-black racism.


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Jo Moon 1964–2016
Jo Moon (also Monks) was a storyteller and therapist. She left Hastings about four years ago to start a new life in a community in Somerset. Sadly, about two years ago she discovered she had breast cancer and, in true Jo style, decided to treat it using alternative therapies. She was fighting the illness and was determined to live till the very end. Unfortunately circumstances around her made it too difficult to carry on and she left this world last month. Her funeral was on 28 October.
I found out about Jo’s death through Emily Johns. Emily’s aunt, Sarah Evans, lives in the house in Carisbrooke Road that Jo used to live in. Last week she hosted a day for friends of Jo’s to remember her. I am sure there are still many people in Hastings who knew Jo, but haven’t yet heard the sad news, and I felt it would be a good idea to pay a short tribute to her in Hastings Online Times.
When I first met Jo she was making films and used to enter the Hastings Film Challenge. She was also a storyteller and worked on a very psychic level. I remember a Hastings Creatives networking meeting in 2011 when she explained how she tells her stories with the help of angels. She was sitting next to a very upright graphic designer. Afterwards I asked the designer if he had felt uncomfortable. He smiled and said he’d enjoyed Jo’s contribution. He described her as ‘good local colour’. Since then, I’ve always thought of Jo as ‘good local colour’. I don’t think she would mind that description – colour was important to Jo.
Jo was also a keen Freecycler and I remember passing a giant tent gleaned from Glastonbury onto her. It was so big I used to call it Buckingham Palace. Some time after I gave it to her, she emailed me: “Just to let you know that the orange and turquoise tent was fantastic at the Green Gathering! It is the first time I have used it. I had to scrap my van before we went away and as a result I could not take my yurt as I would normally do. The tent was not too heavy to carry on a coach and it made the perfect space for storytelling! People seemed to love the environment and there was plenty of space for a small group. It was light because of the colours and generally spacious.” I’m glad the tent found its purpose with Jo.
I am sure other people have Jo memories to share. Please feel free to add them as comments under this article.
I asked Jo’s friend Jabeen in Somerset how she would like to be remembered. She said that Jo would like donations to go to Penny Brohn Cancer Help Centre – this is the place that helped her the most.
Also in: Hastings People« Help hunt for Hastings’ heritage
Against All Odds »

domain: artistic


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The story may be over, but the crossover continues. The further adventures of Ditzy Doo, Planeswalker, among many, many other things. Collection of one-shots set in the Multiverse of Elementals of Harmony. Seriously, read that first.
Rated: K+ - English - Humor/Adventure - Chapters: 8 - Words: 35,639 - Reviews: 16 - Favs: 15 - Follows: 8 - Updated: 10-20-12 - Published: 3-28-12

domain: library


After days of teasing it on their Facebook page, Marvel have finally unveiled their latest trailer for the upcoming addition to the Marvel film franchise, Marvel: Avengers Assemble.
The trailer shows us the recruitment process of The Avengers along with some inter-Avenger battles between the likes of Iron Man, Thor, and Captain America. It also shows a crowd of pedestrians seemingly bowing down to Norse God of mischief, Loki.
And a nice little surprise at the end!
All we know for sure is that there’s going to be plenty of action and explosions
Marvel: Avengers Assemble will be in cinemas 27th April.


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Frequently Asked Questions about Crown Inn Hotel
Which popular attractions are close to Crown Inn Hotel?
Nearby attractions include Cape Jaffa Lighthouse (1.2 km), The Big Lobster (0.7 km), and Kingston Jetty (1.5 km).
What are some of the property amenities at Crown Inn Hotel?
Some of the more popular amenities offered include an on-site restaurant, a lounge, and free parking.
What food & drink options are available at Crown Inn Hotel?
Guests can enjoy an on-site restaurant and a lounge during their stay.
Is parking available at Crown Inn Hotel?
Yes, free parking is available to guests.
What are some restaurants close to Crown Inn Hotel?
Conveniently located restaurants include Bliss, Lacepede Seafood, and Royal Mail Hotel.
Is Crown Inn Hotel located near the city centre?
Yes, it is 0.2 km away from the centre of Kingston SE.

domain: geography


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Biopharmaceutical or biologic drug stability studies for proteins and antibodies including forced degradation, stability storage, structure, physicochemical and potency testing
Biopharmaceutical stability studies for biologic therapeutics are essential to assess sensitivity to factors that could cause aggregation and degradation which impacts biologic activity, product safety, and quality. To reduce the risk of degradation and maintain the biological activity of the product, suitable conditions for storage and shelf life must be established. By understanding degradation routes it is possible to establish which critical quality attributes (CQAs) are more susceptible to change throughout the lifetime of the biologic.
Changes in biopharmaceutical stability due to degradation, chemical or physical instability can alter protein folding and the protein 3-dimensional structure, affecting efficacy. A host of complex analytical methodologies may be required to determine stability and these must be justified and validated. Biological activity assays and the quantitative detection of degradation products are also required to comply with Good Manufacturing Practice (cGMP) compliant stability program. Environmental factors (such as temperature, exposure to oxygen or changes in pH), adsorption onto surfaces and interactions with excipients can all affect stability. In order to demonstrate the stability of biologics, forced degradation studies should be designed and conducted to determine stability-indicating methods suitable for ongoing stability studies.
Our scientists are adept at conducting biopharmaceutical forced degradation, accelerated stability studies, short and long-term stability studies for proteins, biosimilars, antibodies or other biologics. Our expertise in establishing stability-indicating profiles addresses potential degradation pathways for your specific biologic through stress testing and forced degradation. With expert stability-indicating analytical method development skills, we provide assurance that any changes in physicochemical properties, structure, aggregation, biological activity, visual appearance, impurities, excipient degradation, and container/closure interactions will be detected. The knowledge from forced degradation studies, in conjunction with a detailed understanding of the product and process, help to establish CQAs.
External factors such as interaction with formulation components and storage conditions can impact biophysical behaviour and higher-order structure and so it is important to characterise the impact of these factors on structure and conformational stability. We monitor the excipients which may be susceptible to degradation or may also react with the main biologic product.
Our biopharma stability experts have in-depth knowledge of relevant ICH guidelines such as Q5C, "Quality of Biotechnological Products: Stability Testing of Biotechnological/Biological Products", Q1A (R2) and ICH Q6B guidance to ensure we deliver regulatory driven stability data suitable for your biologic and regulatory submission documentation. We bring a diverse range of protein analysis techniques conducted in accordance with Good Manufacturing Practice (GMP) to meet your stability outsourcing requirements. With a global network of GMP compliant stability storage facilities, we provide fully qualified environmental chambers, fridges and freezers with continual monitoring and back-up systems.
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- Gel Electrophoresis (1-D and 2-D SDS-PAGE reducing and non-reducing)
- Western blot
- Isoelectric focusing
- Capillary electrophoresis (CE)
- Total Protein Quantification
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- Spectroscopic profiles
One-Source Solutions for Biopharmaceutical Stability
Coupled with project management and regulatory support, Intertek's biopharmaceutical laboratory services drive your stability programs forward whilst our formulation development team use stability data to provide the next level of support if stability issues are observed. Our thought leaders have over 20 years’ experience in biopharmaceutical stability studies and stability testing to support across a wide range of product types; proteins, monoclonal antibodies, vaccines, PEGylated proteins, antibody drug conjugates, oligonucleotides, glycoproteins and biosimilars. Bringing quality and safety to life, we offer Total Quality Assurance expertise to help you to meet and exceed quality, safety and regulatory standards.


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BUNNY FABRIC BAG
This product is currently sold out.
The cutest, mini toy sack is made of recycled paper, white and brown. Durable and reusable many times over. Once placed and arranged into shape, the paper bag doubles as practical storage as well as a design object in any kids room.
Approx Size: 23 x 27 cm (1.81 x 10.63 in)


Uncovered by rainfall in Sulaymaniyah governorate
36 items of unexploded ordnance discovered on private land
SHARBAZHER – A total of 36 explosive hazards, including various types of mortar shells, artillery shells, and other munitions, have been discovered on privately-owned land in Sharbazher.
Muhsin Sheikh Abdul Karim, head of mine affairs in Sulaymaniyah, told 964media the find followed a tip-off from local security forces about the presence of mines and wartime remnants on a resident’s property in Hebase Gula.
“Our teams were immediately dispatched to the site,” Abdul Karim said.
The unexploded ordnance discovered included 17 60mm mortar shells, eight 82mm mortar shells, one 120mm mortar shell, one 122mm artillery shell, one 105mm artillery shell, five VS50 mines, two RPG-7 launchers, and one hand grenade.
Abdul Karim noted that the ordnance and mines were uncovered due to erosion from rainfall. They were then removed by protection, technical services, and explosive ordnance disposal teams to a secure location for disposal.
Abdul Karim suggested that the unearthed unexploded ordnance likely dates back to actions by the military of the former Baath regime, used against Kurdish insurgents during the 1980s.
He highlighted that the Kurdistan Region contains over 7 million mines, with a significant concentration in the Sulaymaniyah governorate, though precise figures were not provided.


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Immediate opening for a Comprehensive Ophthalmologist/Cataract surgeon in a well-established multi-specialist clinic, due to the upcoming retirement of one of the physicians.
Although our opening is immediate, we are flexible and willing to wait for the right candidate till summer 2020 if needed.
We are seeking an energetic candidate with strong clinical and surgical skills as well as excellent interpersonal skills. Fellowship training in glaucoma, cornea, plastics or any subspecialty is a plus.
Our practice consists of 3 well established ophthalmologists, one if which is fellowship trained in pediatrics, and 2 optometrists. We are part of a large multispecialty group of more than 250 physicians which provides an excellent referral base. Our practice has everything you need for successful practice including excellent ophthalmic techs, an onsite ASC and Epic EMR.
We are part of Advocate Aurora Health which is the 10th largest not-for-profit, integrated health system in the nation. As such, we offer a 2 year salary guarantee of $345,000 and have an excellent benefit package including health, dental, life, disability insurances and retirement program with company match.
Board Certified or Board Eligible candidates.
Advocate Medical Group West is located in Aurora, the 2nd largest city in Illinois and is just 45 minutes west of Chicago! Aurora and the surrounding suburbs offer excellent schools, entertainment as well as many beautiful residential communities.
About Aurora, Illinois
Aurora (“The City of Lights”) is a leader in commerce, education, and entertainment. Aurora was the first city in the world to illuminate all of its streets with electric lights. Aurora is the second largest city in Illinois is not only home to Chicago Premium Outlets, the ultimate shopping destination, but is the area's epicenter of live entertainment! The historic Paramount Theatre provides world-class entertainment, including live dance, music and Broadway-caliber shows. The picturesque 30-acre RiverEdge Park is open year-round and is host to an array of seasonal top-name concerts, festivals and cultural events. Hollywood Casino Aurora is home to the largest poker venue in Illinois, along with top entertainment. Mingled with its hub of arts, fabulous attractions, annual events and outdoor adventure, Aurora has it all.
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Together, we make healthy happen.
Now, as the 10th largest not-for-profit, integrated health system in the nation, Advocate Aurora Health’s combined strength and stability drives us forward. Our integrated delivery model allows our clinicians to offer state-of-the-art, top tier quality care throughout eastern Wisconsin and northern and central Illinois.
Our supportive staff and leadership are committed to an autonomous practice environment and continuously strive to be on the forefront of managing the changing healthcare landscape, advances in technology and innovative approaches to providing impeccable outcomes for our patients.


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Sneak your way through the game in style.
Dark Souls 2 walkthrough and boss guides
Boss guides, bonfires and everything in between.
And still is. Ha! Turn-based DSi multiplay.
DSiWare game for Japan in June.

domain: hobby


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Timex adds a touch of glamour to their spring watches with a fun sparkly face.
Photographed by Julia Rubin.
Vogue Italia September 2012 Face the Future by Steven Meisel featuring Carolyn Murphy. Full editorial on KARLISMYUNKLE.COM
Straight-Up: Kaya Scodelario
Half Brazilian, whole beauty Kaya Scodelario stands straight-up for photographer Stephanie Sian Smith.
Timex S/S 2012


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Gentle Cleanser/Makeup Remover
|Ingredient name||what-it-does||irr., com.||ID-Rating|
|Aqua (Purified Water)||solvent|
|Helianthus Annuus Seed Oil (Organic Sunflower Oil)||emollient||0, 0||goodie|
|Simmondsia Chinensis Seed Oil (Organic First Cold Pressed Jojoba Oil)||emollient||0, 0-2||goodie|
|Cera Alba (Beeswax)||emollient, viscosity controlling, emulsifying, perfuming||0, 0-2|
|Stearic Acid||emollient, viscosity controlling||0, 2-3|
|Glyceryl Stearate||emollient, emulsifying||0, 1-2|
|Xanthan Gum||viscosity controlling|
Evolué Gentle Cleanser/Makeup RemoverIngredients explained
Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
Sunflower does not need a big intro as you probably use it in the kitchen as cooking oil, or you munch on the seeds as a healthy snack or you adore its big, beautiful yellow flower during the summer - or you do all of these and probably even more. And by even more we mean putting it all over your face as sunflower oil is one of the most commonly used plant oils in skincare.
It’s a real oldie: expressed directly from the seeds, the oil is used not for hundreds but thousands of years. According to The National Sunflower Association, there is evidence that both the plant and its oil were used by American Indians in the area of Arizona and New Mexico about 3000 BC. Do the math: it's more than 5000 years – definitely an oldie.
Our intro did get pretty big after all (sorry for that), so let's get to the point finally: sunflower oil - similar to other plant oils - is a great emollient that makes the skin smooth and nice and helps to keep it hydrated. It also protects the surface of the skin and enhances the damaged or irritated skin barrier. Leslie Bauman notes in Cosmetic Dermatology that one application of sunflower oil significantly speeds up the recovery of the skin barrier within an hour and sustains the results 5 hours after using it.
It's also loaded with fatty acids (mostly linoleic (50-74%) and oleic (14-35%)). The unrefined version (be sure to use that on your skin!) is especially high in linoleic acid that is great even for acne-prone skin. Its comedogen index is 0, meaning that it's pretty much an all skin-type oil.
Truth be told, there are many great plant oils and sunflower oil is definitely one of them.
Jojoba is a drought resistant evergreen shrub native to South-western North America. It's known and grown for jojoba oil, the golden yellow liquid coming from the seeds (about 50% of the weight of the seeds will be oil).
At first glance, it seems like your average emollient plant oil: it looks like an oil and it's nourishing and moisturizing to the skin but if we dig a bit deeper, it turns out that jojoba oil is really special and unique: technically - or rather chemically - it's not an oil but a wax ester (and calling it an oil is kind of sloppy).
So what the heck is a wax ester and why is that important anyway? Well, to understand what a wax ester is, you first have to know that oils are chemically triglycerides: one glycerin + three fatty acids attached to it. The fatty acids attached to the glycerin vary and thus we have many kinds of oils, but they are all triglycerides. Mother Nature created triglycerides to be easily hydrolyzed (be broken down to a glycerin + 3 fatty acid molecules) and oxidized (the fatty acid is broken down into small parts) - this happens basically when we eat fats or oils and our body generates energy from it.
Mother Nature also created wax esters but for a totally different purpose. Chemically, a wax ester is a fatty acid + a fatty alcohol, one long molecule. Wax esters are on the outer surface of several plant leaves to give them environmental protection. 25-30% of human sebum is also wax esters to give us people environmental protection.
So being a wax ester results in a couple of unique properties: First, jojoba oil is extremely stable. Like crazy stable. Even if you heat it to 370 C (698 F) for 96 hours, it does not budge. (Many plant oils tend to go off pretty quickly). If you have some pure jojoba oil at home, you should be fine using it for years.
Second, jojoba oil is the most similar to human sebum (both being wax esters), and the two are completely miscible. Acne.org has this not fully proven theory that thanks to this, jojoba might be able to "trick" the skin into thinking it has already produced enough sebum, so it might have "skin balancing" properties for oily skin.
Third, jojoba oil moisturizes the skin through a unique dual action: on the one hand, it mixes with sebum and forms a thin, non-greasy, semi-occlusive layer; on the other hand, it absorbs into the skin through pores and hair follicles then diffuses into the intercellular spaces of the outer layer of the skin to make it soft and supple.
On balance, the point is this: in contrast to real plant oils, wax esters were designed by Mother Nature to stay on the surface and form a protective, moisturizing barrier and jojoba oil being a wax ester is uniquely excellent at doing that.
It's the yellow, solid stuff that you probably know from beeswax candles. It's a natural material produced by honey bees to build their honeycomb.
As for skincare, it's used as an emollient and thickening agent. It's super common in lip balms and lipsticks.
A common multi-tasker fatty acid. It makes your skin feel nice and smooth (emollient), gives body to cream type products and helps to stabilize water and oil mixes (aka emulsions).
A super common, waxy, white, solid stuff that helps water and oil to mix together, gives body to creams and leaves the skin feeling soft and smooth.
Chemically speaking, it is the attachment of a glycerin molecule to the fatty acid called stearic acid. It can be produced from most vegetable oils (in oils three fatty acid molecules are attached to glycerin instead of just one like here) in a pretty simple, "green" process that is similar to soap making. It's readily biodegradable.
It also occurs naturally in our body and is used as a food additive. As cosmetic chemist Colins writes it, "its safety really is beyond any doubt".
It's one of the most commonly used thickeners and emulsion stabilizers. If the product is too runny, a little xanthan gum will make it more gel-like. Used alone, it can make the formula sticky and it is a good team player so it is usually combined with other thickeners and so-called rheology modifiers (helper ingredients that adjust the flow and thus the feel of the formula). The typical use level of Xantha Gum is below 1%, it is usually in the 0.1-0.5% range.
Btw, Xanthan gum is all natural, a chain of sugar molecules (polysaccharide) produced from individual sugar molecules (glucose and sucrose) via fermentation. It’s approved by Ecocert and also used in the food industry (E415).
A semi-essential (infants cannot synthesize it, but adults can) amino acid that is one of the primary building blocks of hair keratin and skin collagen. It's a natural moisturizing factor, a skin hydrator and might also help to speed up wound healing.
Arginine usually has a positive charge (cationic) that makes it substantive to skin and hair (those are more negatively charged surfaces) and an excellent film former. Thanks to the positive charge, it also creates a complex with AHAs (AHAs like to lose a hydrogen ion and be negatively charged, so the positive and the negative ions attract each other) that causes a "time-release AHA effect" and reduces the irritation associated with AHAs.
A helper ingredient that helps to make the products stay nice longer, aka preservative. It works mainly against fungi.
It’s pH dependent and works best at acidic pH levels (3-5). It’s not strong enough to be used in itself so it’s always combined with something else, often with potassium sorbate.
|irritancy, com.||0, 0|
|irritancy, com.||0, 0-2|
|what‑it‑does||emollient | viscosity controlling | emulsifying | perfuming|
|irritancy, com.||0, 0-2|
|what‑it‑does||emollient | viscosity controlling|
|irritancy, com.||0, 2-3|
|what‑it‑does||emollient | emulsifying|
|irritancy, com.||0, 1-2|


Yesterday Apple announced the lauch of their New iPad. Against expectations it isn't to be called the iPad 3 but just New iPad. The main advances are the exceptionally high resolution screen and the new A5X processor, which Apple claim is twice as fast as the A5 processor used in the iPad 2.
To see what some fo the technology publications click below:
It will be interesting to see what the new Samsung Android tablet, due for release in the coming weeks, will offer.


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Look what I found this morning
I dont know what got into my mind this morning, but I thought I would hunt down a tutorial on this apron Ive been wanting to make. I came across this very nice persons youtube video and she had this quick and easy way of making the apron I am going to make probably this weekend.. What is awesome is she gives you the pattern too. Its all handmade, nothing is exact, but its beautiful. I already have some fabric, but its much heavier than what she uses. Now she makes me want to make a trip to Ikea just for the table cloth that she uses…and she said she…
Not Sure What To Name This, Any Ideas?
Yesterday I was playing around
Art Bundle for Good #4 is Here!
I’m super excited to be contributing to Art Bundle for Good #4 and it is available NOW, but it won’t be around for long. The sale ends in 5 days. There are $4000 worth of courses, workbooks, and other resources on topics like painting, watercolor, calligraphy, drawing, mixed media arts, creativity, and more all bundled together for one low price. This is an amazing opportunity to get 98 art resources at such a low price. With so many products, it works out to about $1 per course! Art is such a great investment in your creativity, personal development and happiness. The Art Bundle for Good is the perfect investment in…
Have you ever been so messy that every room you have that you use for art is so cluttered that you done know where things are anymore? And its not that you are being messy, its that you have been so busy creating and you get so excited that you use this and that…and it gets left on the table…or left in a spot that is not in its assigned spot. I am actually laughing at myself right now thinking about assigned spots. I have 2 rooms I work out of. Yes, I am fortunate to have that option in my house. I have the “craft room” and our youngest…
This painting kind of made itself. I created an acrylic pour with not thought in mind. Just wanted to have a little fun and relaxation. After it dried, I thought..wow…this is really pretty! I was doing some exploring online like I tend to do from time to time…and this painting of Monet showed up…and that’s when I knew what I was going to do with this painting. So I got to work…painted the flowers put in some grassy stuff. Then I decided to put resin on it. The first layer looked a little boring to me, so I added more umph to the flowers, added some shading, put in some…


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BACKGROUND AND PURPOSE: Recanalization status after intravenous thrombolysis (IVT) in patients with ischemic stroke is a reference point to proceed with a rescue reperfusion intervention, although early neurological improvement (NI) may preclude endovascular procedures. We aimed to evaluate the importance of restoration of blood flow at the arterial occlusion site in subgroups of patients with stroke stratified by early NI after IVT. METHODS: The following patients were recruited from the Safe Implementation of Treatment in Stroke-International Stroke Thrombolysis Register: (1) with baseline vessel occlusion documented by computed tomographic (CT) or magnetic resonance (MR) angiography and follow-up angioimaging between 22 and 36 hours after IVT available; and (2) with dense cerebral artery sign on admission CT scan and results of follow-up CT reported. Recanalization at 24 hours was defined as absence of vessel occlusion or as resolution of dense cerebral artery sign on follow-up 22- to 36-hour imaging. NI was assessed at 2 hours and 24 hours after IVT and was defined as improvement by 20% from baseline National Institute of Health Stroke scale score. Primary outcome measure was independence, defined as modified Rankin scale score 0 to 2 after 3 months. RESULTS: Of 28136 cases registered between December 2003 and November 2009, 5324 cases (19%) met the inclusion criteria. Patients with both NI at 2 hours post-treatment and vessel recanalization had the best chances to achieve independence at 3 months (adjusted odds ratio, 15.8; 95% confidence interval, 12.5-20.0), followed by those who had NI despite persistent occlusion (adjusted odds ratio, 4.7; 95% confidence interval, 3.6-6.1); and those without NI despite recanalization (adjusted odds ratio, 2.7; 95% confidence interval, 2.2-3.3). CONCLUSIONS: Recanalization of an occluded artery in acute stroke is associated with favorable functional outcome both in patients with and without NI after IVT. In future evaluations of mechanical thrombectomy and other additional strategies, recanalization should be considered in patients with persisting occlusion after IVT even after significant NI.
Importance of cerebral artery recanalization in patients with stroke with and without neurological improvement after intravenous thrombolysis / T. V., Kharitonova; T. P., Melo; G., Andersen; J. A., Egido; J., Castillo; N., Wahlgren; Sits, Investigators; Toni, Danilo. - In: STROKE. - ISSN 0039-2499. - 44(2013), pp. 2513-2518. [10.1161/STROKEAHA.111.000048]
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|Titolo:||Importance of cerebral artery recanalization in patients with stroke with and without neurological improvement after intravenous thrombolysis.|
|Data di pubblicazione:||2013|
|Citazione:||Importance of cerebral artery recanalization in patients with stroke with and without neurological improvement after intravenous thrombolysis / T. V., Kharitonova; T. P., Melo; G., Andersen; J. A., Egido; J., Castillo; N., Wahlgren; Sits, Investigators; Toni, Danilo. - In: STROKE. - ISSN 0039-2499. - 44(2013), pp. 2513-2518. [10.1161/STROKEAHA.111.000048]|
|Appartiene alla tipologia:||01a Articolo in rivista|

domain: medical


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The year slot machines a demo version, so the player can have fun trying the various slots without having to make a deposit. In part, this applies because the video slots are suitable for beginners, and the cash prize and bonuses are probably the best in the online game industry. An applause also goes to intuition to dedicate promos to users who play from mobile devices.
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There are transforming symbols, respins, stacked symbols, wild and free spins with extra.
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I was told that the payment has left my account and has been successfully accredited to the recipient’s bank account. Some companies can offer interesting courses or quick payments. Today there is almost no need for confirmation text messages or codes to authorize transactions, payments are increasingly rapid and injured in those who perform them, since you do not see the money that physically leaves our pockets. The top Gun Payout of this slot settles at 94.93%.
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However, we must not be fooled by the movies, because it is absolutely not possible to win safe money to the casino playing blackjack, but there are strategies that can be helpful to the player. The side bets instead, just as happens on the Blackjack Double Xposure, are not allowed.
The first to play will be the person sitting to the left of the dealer who, as a first operation, will necessarily fish a card from the covered deck and open his game looking for some of the possible combinations. The played bonuses will replace deposit bonuses: our forecasts on this year’s online casinos promotions include a trend that we have observed both among Italian operators and in numerous foreign casinos. Among the games available in Live Mode, we find: Wonderland, various types of roulette, Blackjack, Buffalo Blitz, Live Caribbean Stud, Live Texas Holdem, Football Studio and many others.
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Each casino shows the probability of winning and the AAMS license, which makes it a legal casino. The most prestigious are the sites for which authorization from Malta is released. Moreover, every week Titanbet offers loyalty bonuses to reward weekly gaming activity: these will increase based on the customer’s VIP level to which they are attributed. In Italy after the first one that is Stevegas, other casinos have purchased the license given the popularity of the games.
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Wednesday, August 24, in fact, he released a hat-trick of new slots, all from the forge of the NextGen Gaming provider. Betting partnership between Betway and Eintracht Frankfurt sees thus increasing the portfolio of football sponsorships of the British operator.
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Jackpot 6000 Slot Machine is a Netent slot machine. The list of all the best behaviors to keep, to avoid finishing in the compulsive game can be provided. I was playing from 9:00 to about 150.
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30 Nov 2017 Modafinil can be obtained easily without prescription and over the internet from countries that may not have the same pharmaceutical
Modafinil is used to treat excessive sleepiness caused by sleep apnea, What is modafinil, and how does it work (mechanism of action)?. Modafinil is an oral drug that is used for improving wakefulness in patients with excessive 7 Feb 2018 Abstract. Modafinil is used because of its wakefulness-promoting properties for treatment of diseases associated with extreme sleepiness (i.e., 22 Dec 2020 What is Modafinil? Modafinil has been marketed online as a 'smart drug' that keeps you alert and focused for long periods of time with little to Modafinil is eliminated mainly by metabolism, with most of the metabolites being excreted in the urine. Cytochrome P450 3A4 may be involved in the metabolism 7 Oct 2013 Modafinil is an exceptionally weak, but apparently very selective, DA transporter inhibitor. The pharmacodynamic response to modafinil, as 14 Nov 2016 Modafinil is a wake-promoting drug and has been widely used for daytime sleepiness in patients with narcolepsy and other sleep disorders.
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In their review of the literature 1 Dec 2016 Modafinil (MOD) exhibits therapeutic efficacy for treating sleep and psychiatric disorders; however, its mechanism is not completely understood. Are you looking to purchase Modafinil narcolepsy medication online? BUY now | FREE* Next Day Delivery Available | Cheapest Price GUARANTEED. 17 Mar 2009 Provigil, a drug manufactured by Cephalon Inc. to treat sleep disorders. If ever there was a safe recreational drug, modafinil seemed to be it. The Modafinil: Sharp Your Focus, Improve Concentration and Unlock Hidden Potential of Your Brain (Strong Body, Smart Brain Book 3) eBook: Weisman, Robert: 17 Sep 2020 Modafinil Mechanisms Of Action.
Modafinil is in a class of medications called wakefulness promoting agents. It works by changing the amounts of certain natural substances in the area of the brain
However with Vilafinil the main difference What is Modafinil? Modafinil (Brand name: Provigil) is a wakefulness-promoting prescription drug that reduces the extreme sleepiness that accompanies sleep disorders including narcolepsy, obstructive sleep apnea, and shift work disorder (SWD). Dec 30, 2020 · A 200 mg modafinil tablet will produce effects lasting about 12–15 hours.
Modafinil is a eugeroic medication, which means it is wakefulness-promoting agent. It is a central nervous system (CNS) stimulant medication used primarily to help people remain awake, combat fatigue, and increase concentration.
Modafinil is a racemic compound. The chemical name for modafinil is 2- [ (diphenylmethyl)sulfinyl]acetamide. The molecular formula is C 15 H 15 NO 2 S and the molecular weight is 273.35. Modafinil is a Schedule IV prescription drug that was manufactured by Cephalon before they were bought out by Teva Pharmaceuticals. The United States Food and Drug Administration (FDA) approved Modafinil in 1998 under the brand name “Provigil” to treat excessive daytime sleepiness in the following conditions [ 1 ]: See full list on americanaddictioncenters.org See full list on medlineplus.gov See full list on everydayhealth.com MODAFINIL is used to treat excessive sleepiness caused by certain sleep disorders.
Modafinil is a central nervous system vigilance promoting agent, which posseses neuroprotective properties. Features and Benefits This compound was developed by Teva. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. Other Notes Modafinil has been a vital part of the everyday lives of many individuals.
Learn more: Mayo Clinic facts about coronavirus disease 2019 (COVID-19) Our COVID-19 patient and visitor guidelines, plus trusted health information Latest on COVID-19 vaccination by site: Arizona patient vaccination updates Arizona, Florida patient vaccination updates Florida, Rochester patient 2/16/2012 8/22/2007 12/30/2020 10/25/2011 8/24/2017 Modafinil is a medication shown to relieve extreme sleepiness in people who have been diagnosed with sleep disorders such as narcolepsy, obstructive sleep apnea and shift work sleep disorder. Modafinil is effective due to its ability to interact with the sleep-wake cycle. Although it helps most patients, taking Modafinil will not cure your 6/5/2019 6/16/2020 Human laboratory studies (Rush, Kelly, Hays, Baker & Wooten, 2002) and early case reports have prompted interest in modafinil, a novel wake promoting agent, recently approved for narcolepsy.Modafinil promotes wakefulness, vigilance and alertness and may have value in treating psychostimulant withdrawal symptoms such as hypersomnia, poor concentration and low mood. 4/20/2017 9/18/2019 modafinil occurred within 1 to 5 weeks after treatment initiation. However, isolated cases have been reported after prolonged treatment (e.g., 3 months). Accordingly, duration of therapy cannot be relied upon as a means to predict the potential risk heralded by the first appearance of a rash. Modafinil gained popularity among students, who use it during long study sessions to remain focused and improve retention because of the cognition enhancing effects of Modafinil.
Modafinil is a stimulant drug marketed as a 'wakefulness promoting agent' and is one of the stimulants used in the treatment of narcolepsy. Narcolepsy is caused by dysfunction of a family of wakefulness-promoting and sleep-suppressing peptides, the orexins, whose neurons are activated by modafinil. Modafinil is also used to treat other sleeping disorders like those experienced by shift workers or people suffering from sleep apnea. Another common use is in the treatment of attention deficit disorder (ADHD). Off-label use of modafinil involves sleep-deprived students or business professionals looking to boost their efficiency at work or school. Armodafinil is an oral drug that is used to promote wakefulness.
Modafinil Accession Number DB00745 Description. Modafinil is a stimulant drug marketed as a 'wakefulness promoting agent' and is one of the stimulants used in the treatment of narcolepsy. Narcolepsy is caused by dysfunction of a family of wakefulness-promoting and sleep-suppressing peptides, the orexins, whose neurons are activated by modafinil. 8/22/2017 Modafinil is a synthetic central nervous system stimulant with wakefulness-promoting activity. Modafinil appears to inhibit dopamine reuptake, resulting in an increase in extracellular dopamine.This agent exhibits pronounced wakefulness-promoting activity (without sympathomimetic activity) and may improve cognitive function in certain clinical settings. Don't delay your care at Mayo Clinic.
Although not all of these side effects may occur, if they do occur they may need medical attention. MODAFINIL is used to treat excessive sleepiness caused by certain sleep disorders.nejnovější zprávy o bitcoinech v hindštině
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New York (The Gaslamp Post) – A worker at a Manhattan-area deli reportedly accused a customer of shoplifting last week, and then proceeded to publicly subject that customer to a pat-down search. The customer, none other than Actor Forest Whitaker was at the Milano Market Deli on Friday, when an employee had stopped him when he thought he had seen him take an item and hide it on his person.
According to the New York Post, the employee stopped Whitaker and then patted him down in front of other customers. No stolen item was found on him.
“An employee from the store came outside to speak with him and to apologize,” Crupe said in a statement. “He told Mr. Whitaker that the cameras in the store were at a bad angle and that he could not see if Forest had stolen anything.”
An employee of the deli also attempted to make it up to Whitaker by offering him free food. Whitaker reportedly asked that the store change the way it treats it’s customers.
In a statement released by Whitaker’s spokesman stated that his civil rights were violated.
“This was an upsetting incident given the fact that Forest did nothing more than walk into the deli,” Jennifer Plante said. “Forest did not call the authorities at the request of the worker who was in fear of losing his employment.”

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I'm building a macro using VBA and Inventor 2011 that will take an assembly, open each part in that assembly and save the part as a bitmap. All was working well until it hit a content center component.
When it opens the content center file and attempts the SaveAsBitmap it errors with "Run-time error, Method 'SaveAsBitmap' of object 'View' failed". If I open the file I can do a save copy as bitmap without error.
The code I'm using is as follows... any thoughts on why its failing with Content Center Parts?