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NMDA receptors are altered in the substantia nigra pars reticulata and their blockade ameliorates motor deficits in experimental parkinsonism.
- 作者列表："Sitzia G","Mantas I","Zhang X","Svenningsson P","Chergui K
:In Parkinson's disease (PD) reduced levels of dopamine (DA) in the striatum lead to an abnormal circuit activity of the basal ganglia and an increased output through the substantia nigra pars reticulata (SNr) and the globus pallidus internal part. Synaptic inputs to the SNr shape its activity, however, the properties of glutamatergic synaptic transmission in this output nucleus of the basal ganglia in control and DA-depleted conditions are not fully elucidated. Using whole-cell patch-clamp recordings and pharmacological tools, we examined alterations in glutamatergic synaptic transmission in the SNr of a mouse model of PD, i.e. mice with unilateral 6-OHDA lesion of DA neurons in the substantia nigra pars compacta, as compared to control mice. We found that AMPA receptor (AMPAR)-mediated spontaneous and evoked excitatory postsynaptic currents (sEPSCs and eEPSCs) were not altered. The AMPA/NMDA ratio was significantly decreased in 6-OHDA-lesioned mice, suggesting an increased synaptic function of NMDA receptors (NMDARs) in DA-depleted mice. The decay kinetics of NMDAR-eEPSCs were faster in 6-OHDA-lesioned mice, indicating a possible change in the subunit composition of synaptic NMDARs. In control mice NMDAR-eEPSCs were mediated by diheteromeric NMDARs made of GluN2A, GluN2B and GluN2D. In 6-OHDA-lesioned mice the function of diheteromeric NMDARs containing either GluN2B or GluN2D was dramatically decreased, whereas the function of diheteromeric NMDARs made of GluN2A was preserved. Microinjections of an NMDAR antagonist into the SNr of 6-OHDA-lesioned mice resulted in significant improvements in spontaneous locomotion. This study identifies novel alterations occurring at excitatory synapses in the basal ganglia output nucleus following DA depletion. An increased synaptic NMDAR function, due to an altered subunit composition, might contribute to hyperactivation of SNr neurons in the DA depleted state and to motor impairments in PD.
: 帕金森病 (PD) 患者多巴胺 (DA) 水平降低在纹状体中导致基底节的异常环路活动，并通过黑质网状部 (SNr) 和苍白球内部部分增加输出。SNr 的突触输入塑造了它的活性，然而，在控制和 DA 耗尽的条件下，基底节的这个输出核中的谷氨酸能突触传递的特性尚未完全阐明。使用全细胞膜片钳记录和药理学工具，我们检测了 PD 小鼠模型 SNr 中谷氨酸能突触传递的改变，即与对照组小鼠相比，黑质致密部 DA 神经元单侧 6-OHDA 病变的小鼠。我们发现 AMPA 受体 (AMPAR) 介导的自发和诱发的兴奋性突触后电流 (sEPSCs 和 eEPSCs) 没有改变。AMPA/NMDA 比值在 6-ohda 损伤小鼠中显著降低，提示 DA 耗竭小鼠 NMDA 受体 (NMDARs) 的突触功能增加。NMDAR-eEPSCs 的衰变动力学在 6-ohda 损伤小鼠中更快，表明突触 NMDARs 的亚基组成可能发生变化。在对照组小鼠中，NMDAR-eEPSCs 由 GluN2A 、 GluN2B 和 GluN2D 制成的二异基因 NMDARs 介导。在 6-ohda 损伤的小鼠中，含有 GluN2B 或 GluN2D 的二异聚 NMDARs 的功能显著降低，而由 GluN2A 制成的二异聚 NMDARs 的功能得以保留。将 NMDAR 拮抗剂微量注射到 6-ohda 损伤小鼠的 SNr 中，可显著改善自发运动。本研究确定了 DA 耗竭后基底节输出核兴奋性突触发生的新变化。突触 NMDAR 功能增加，由于亚基组成改变，可能导致 DA 耗尽状态下 SNr 神经元的过度激活和 PD 的运动损伤。
METHODS::Identifying disease-causing pathways and drugs that target them in Parkinson's disease (PD) has remained challenging. We uncovered a PD-relevant pathway in which the stress-regulated heterodimeric transcription complex CHOP/ATF4 induces the neuron prodeath protein Trib3 that in turn depletes the neuronal survival protein Parkin. Here we sought to determine whether the drug adaptaquin, which inhibits ATF4-dependent transcription, could suppress Trib3 induction and neuronal death in cellular and animal models of PD. Neuronal PC12 cells and ventral midbrain dopaminergic neurons were assessed in vitro for survival, transcription factor levels and Trib3 or Parkin expression after exposure to 6-hydroxydopamine or 1-methyl-4-phenylpyridinium with or without adaptaquin co-treatment. 6-hydroxydopamine injection into the medial forebrain bundle was used to examine the effects of systemic adaptaquin on signaling, substantia nigra dopaminergic neuron survival and striatal projections as well as motor behavior. In both culture and animal models, adaptaquin suppressed elevation of ATF4 and/or CHOP and induction of Trib3 in response to 1-methyl-4-phenylpyridinium and/or 6-hydroxydopamine. In culture, adaptaquin preserved Parkin levels, provided neuroprotection and preserved morphology. In the mouse model, adaptaquin treatment enhanced survival of dopaminergic neurons and substantially protected their striatal projections. It also significantly enhanced retention of nigrostriatal function. These findings define a novel pharmacological approach involving the drug adaptaquin, a selective modulator of hypoxic adaptation, for suppressing Parkin loss and neurodegeneration in toxin models of PD. As adaptaquin possesses an oxyquinoline backbone with known safety in humans, these findings provide a firm rationale for advancing it towards clinical evaluation in PD.
METHODS::Huntington's disease (HD) is an inherited progressive neurodegenerative disease characterized by brain atrophy particularly in the striatum that produces motor impairment, and cognitive and psychiatric disturbances. Multiple pathogenic mechanisms have been proposed including dysfunctions in neurotrophic support and calpain-overactivation, among others. Kinase D-interacting substrate of 220 kDa (Kidins220), also known as ankyrin repeat-rich membrane spanning (ARMS), is an essential mediator of neurotrophin signaling. In adult brain, Kidins220 presents two main isoforms that differ in their carboxy-terminal length and critical protein-protein interaction domains. These variants are generated through alternative terminal exon splicing of the conventional exon 32 (Kidins220-C32) and the recently identified exon 33 (Kidins220-C33). The lack of domains encoded by exon 32 involved in key neuronal functions, including those controlling neurotrophin pathways, pointed to Kidins220-C33 as a form detrimental for neurons. However, the functional role of Kidins220-C33 in neurodegeneration or other pathologies, including HD, has not been explored. In the present work, we discover an unexpected selective downregulation of Kidins220-C33, in the striatum of HD patients, as well as in the R6/1 HD mouse model starting at early symptomatic stages. These changes are C33-specific as Kidins220-C32 variant remains unchanged. We also find the early decrease in Kidins220-C33 levels takes place in neurons, suggesting an unanticipated neuroprotective role for this isoform. Finally, using ex vivo assays and primary neurons, we demonstrate that Kidins220-C33 is downregulated by mechanisms that depend on the activation of the protease calpain. Altogether, these results strongly suggest that calpain-mediated Kidins220-C33 proteolysis modulates onset and/or progression of HD.
METHODS:BACKGROUND:Neuroinflammation has been recognized as an important factor in the pathogenesis of Alzheimer's disease (AD). One of the most recognized pathways in mediating neuroinflammation is the prostaglandin E2-EP1 receptor pathway. OBJECTIVE:Here, we examined the efficacy of the selective EP1 antagonist ONO-8713 in limiting amyloid-β (Aβ), lesion volumes, and behavioral indexes in AD mouse models after ischemic stroke. METHODS:Transgenic APP/PS1, 3xTgAD, and wildtype (WT) mice were subjected to permanent distal middle cerebral artery occlusion (pdMCAO) and sham surgeries. Functional outcomes, memory, anatomical outcomes, and Aβ concentrations were assessed 14 days after surgery. RESULTS:pdMCAO resulted in significant deterioration in functional and anatomical outcomes in the transgenic mice compared with the WT mice. No relevant differences were observed in the behavioral tests when comparing the ONO-8713 and vehicle-treated groups. Significantly lower cavitation (p = 0.0373) and percent tissue loss (p = 0.0247) were observed in APP/PS1 + ONO-8713 mice compared with the WT + ONO-8713 mice. However, the percent tissue injury was significantly higher in APP/PS1 + ONO-8713 mice compared with WT + ONO-8713 group (p = 0.0373). Percent tissue loss was also significantly lower in the 3xTgAD + ONO-8713 mice than in the WT + ONO-8713 mice (p = 0.0185). ONO-8713 treatment also attenuated cortical microgliosis in APP/PS1 mice as compared with the vehicle (p = 0.0079); however, no differences were observed in astrogliosis across the groups. Finally, APP/PS1 mice presented characteristic Aβ load in the cortex while 3xTgAD mice exhibited very low Aβ levels. CONCLUSION:In conclusion, under the experimental conditions, EP1 receptor antagonist ONO-8713 showed modest benefits on anatomical outcomes after stroke, mainly in APP/PS1 mice.


An inspirational apprentice leader who has guided more than 1,500 young Teessiders into successful careers has been praised following her retirement.
Middlesbrough Council’s apprentice co-ordinator Ann White called time on her own successful career recently following three decades with the authority.
Ann worked with apprentices for 32 years and managed the service for 20 years and one of her last days at work saw a celebration of achievement event for the Council’s latest groups of young success stories.
The event saw 55 young people receive their certificates for their apprenticeship achievements in Middlesbrough Town Hall’s Council Chamber from Mayor Dave Budd.
Watched on by their families and employers, the apprentices were celebrated for completing either their Level 2 or Level 3 programme over a 12 or 18-month period, through Middlesbrough Community Learning training centre.
They have done this while working for Middlesbrough Council, Cleveland Police, Kier Group, Middlesbrough primary schools and for other local key organisations.
Ann said: “I have loved working for Middlesbrough Council and I am especially proud of all of the apprentices who have participated in the Council’s apprenticeship programme and have gone on to great success.”
Many apprentices helped by Ann have gone on to higher positions and some are now in management posts with the Council.
The Mayor Mr Budd said: “I am delighted to be celebrating the achievements of our young people. Apprenticeships play a big part in helping young people into long-term employment by equipping them with the skills that employers are looking for.
“Their work is very much appreciated and I would like to pay tribute to their success and wish them all the very best with their future careers. Ann has made an enormous contribution in preparing apprentices for the world of work for more than 30 years and I also want to thank her and wish her well in her retirement.”
Anyone interested in an apprenticeship with Middlesbrough Community Learning should contact Carole Thorpe on 01642 811414, or businesses wishing to take an apprentice on should contact Kevin Sedgwick on 01642 654553.


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Good news come in pairs! XD (Jaejoong ranked #2 on Japan’s Twipple for April, see here).
Also, Jaejoong did very well in a ranking with top Japanese celebrities of Japan.
“Girls Walker” is a popular magazine for Japanese teenage girls. It has a music section which it terms “Music Walker.” Readers may remember that Jaejoong has ranked among the very top stars of Japan in a survey by Music Walker in February as an artist to whom one would like to give chocolates for Valentines Day. (See here)
This week, Jaejoong repeated his feat, in a survey on which artist these girls would like to have as their boyfriend:
(1) Hyde of L’Arc ~ en ~ Ciel
(2) Yamada Ryosuke of Hey! Say! JUMP
(3) Fukuyama Masaharu
(4) Yamashita Tohomisa of NEWS, aka YamaPi
(5) Jaejoong of JYJ
(6) Takuya of UVERworld
(7) Takahiro of EXILE
(8) Masaki Aiba of Arashi
(9) Sakurai Sho of Arashi
(10) Tachibana Keita of W-inds
Amazing and so nice to see Jaejoong compete and hold his own with the top of the top artists of Japan, such as the above!

domain: artistic


Damn, this February is helluva good for muscle car enthusiasts – it already unveiled the 2012 Charger SRT8, 2012 ZL1 Camaro and, for the first time since 1970 – the all new 2012 Shelby GT350 Convertible.
The roofless Shelby comes in 3 different V8 engines: 320 kW [429 HP], 392 kW [526 HP] and 466 kW [625 HP] beast which has 75 HP more than the sensational-comeback ZL1. Of course, Shelby comes in a limited 350 unit production run. It isn’t hard to guess, huh? Well, this’ll make them worth the price tag for sure. Mustang comes with 2 brand new colors: Race Red and Kona Blue both having traditional Le Mans stripes. As Carroll said himself “we’re repeating history”.
Charger, Camaro, Mustang… What else? February, please, let it be something more about the 2013 Viper, please. Well, for now it is quite enough. Muscle car war isn’t over yet.


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Glo Skin Beauty Skin Brightening Serum treats skin discolouration with a full spectrum of natural brighteners and smoothing ingredients to create a fresh glowing complexion. This skin lightening serum helps inhibit hyperpigmentation induced by cellular stress. What's more, this skin pigmentation brightening treatment smoothes and improves skin texture, revealing glowing skin below the surface.
Tyrostat™ (Rumex Occidentalis Extract) – A natural skin lightener that works by inhibiting melanin production by the tyrosinase enzyme.
Arbutin – Promotes skin lightening by blocking melanin synthesis by tyrosinase. A natural plant-based derivative of hydroquinone.
Azelaic Acid – Treats hyperpigmentation by inhibiting tyrosinase activity. Suppresses the growth of follicle bacteria and scavenges free radicals.
Morus Alba (Mulberry) Bark Extract – Brightens skin by inhibiting tyrosinase. Antioxidant and anti-inflammatory.
Lactic Acid (L-) – A hydrating Alpha Hydroxy Acid that gently exfoliates while improving skin tone and texture including pigmentation discolorations and fine lines.
Glycolic Acid – An Alpha Hydroxy Acid that stimulates exfoliation and treats photoaging by improving skin texture, uneven pigmentation and fine lines.
All skin types including hyperpigmentation, sun and environmental damage, freckling, dullness. Not suitable for sensitive skin.
HOW TO USE
Apply a small amount of skin brightening serum to target areas or all over skin after cleansing and toning. If needed, follow with a Glo Skin Beauty moisturiser. Use twice daily.
Sun alert: the Hydroxy Acids in this skin lightening serum may increase your skin’s sensitivity to sunlight.
Wearing a sunscreen daily is highly recommended.
It is particularly important to consider sun protection during a skin brightening treatment.
Unprotected or excessive sun exposure can delay or inhibit results and even exacerbate existing hyperpigmentation problems.
This product is part of a professional skincare range specifically designed by dermatologists to be used on both normal and post-procedure treated skin.
Glo Skin Beauty Purifying Gel Cleanser purifies skin without stripping away natural moisture. Including Salicylic Acid to deeply cleanse pores while antioxidants protect and soothe...View full product details
Glo Skin Beauty Clear Skin Body Spray, formerly known as the Back acne spray treatment, is very much a simple acne body spray to help...View full product details
Glo Skin Beauty Renew Serum is a potent multi-action skin-renewing retinol serum. If you're looking for skincare for mature skin or adult acne this oil...View full product details
Glo Skin Beauty Clear Acne Cleanser helps thoroughly cleanse skin while treating breakouts. Treat adult acne with this 2% Salicylic Acid acne cleanser, which refines...View full product details

domain: chemistry


Fenner Dunlop ECS, Flexco, PPI, and others manufactures high quality products including idlers, cleaners, conveyor pulleys, drives and conveyor structure used in mining, quarrying, agriculture, ship loading, utility, hard rock mining, material and bulk solids handling industries.
- Idlers – For carrying and smoothly moving conveyor belt. Available in 20-, 35- and 45-degree configurations for containment of the material being conveyed.
- Impact Cradles – Similar to the slider bed, these can come in a variety of configurations and designs. Impact rollers – Rollers combined with impact bars. Application specific.
- Slider Beds – utilized to cradle and support the material in an impact zone.
- Primary & Secondary Cleaners – for cleaning of the conveyor belt to reduce or eliminate carry-back of material. Reduced carry-back leads to reduced maintenance costs.
- Cleaner Blades – Replacement bladed utilized on the various belt cleaner configurations above.
- Plows / V-Plows – Typically used to clean material from spillage on the clean side of a conveyor belt to eliminate materials from building up in the tail section of a conveyor belt.
- Skirtboards & Seal Systems – These are material containment systems designed to reduce spillage and dust.
- Ceramic Lagging – used to improve traction on drive pulleys. Several different configurations depending on application.
- Pulleys – Pulleys come in several versions for a conveyor system; Drum type: used for drive, snub and bend pulleys. Wing type; typically used for take-up systems. There are various designs for each type of pulley. Application will dictate the correct choice.
- Structure – For mounting the conveyor components; Idlers, return rollers, pulleys, conveyor belt, Drive systems, take-up and tail components.
- Customized Products – There are several custom components available for a conveyor system; Depending on the system and product conveyed various custom components can be engineered to better control impact ones, tracking, material flow and wear to the system.


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Member for Hawkesbury Dominic Perrottet is encouraging Hawkesbury non-government organisations (NGO’s) working in the drug and alcohol sector to enter an expression of interest in the Government’s Early Intervention Innovation Fund that was recently announced by the Assistant Minister for Health, Pru Goward.
The Early Intervention Innovation Fund will provide $8 million over four years to build the evidence base for early intervention models to support people at risk with a particular focus on young people using drugs.
The Early Intervention Innovation Fund provides two funding pathways including:
The Non-Government Organisation (NGO) Evaluation Grants – focusing on building the evaluation capacity of NGOs to evaluate existing programs to build an evidence base and ultimately improve program delivery. Grants of $30,000 to $150,000 will be provided over two years.
The Alcohol and Drug Early Intervention Innovation Grants – which allows NGO’s and their partners, including the NSW health system, to drive new innovative approaches for the delivery of early intervention to vulnerable young people. Grants of $50,000 to $1 million over two years will be awarded.
Mr Perrottet said that it was a great opportunity for NGO’s in the Hawkesbury to develop new and innovative ideas to increase and improve early intervention services for young people in the community.
“I encourage NGO’s within the community to apply for these grants so we can reach out to young people in our community and prevent them from going down the path of addiction,” Mr Perrottet said.
“This fund is one component of the Government’s record investment in Drug & Alcohol services and shows our commitment to investing in evidence based services that will make a real impact in stopping drug abuse before it happens.”
Assistant Minister for Health Pru Goward said the Government is building a system that empowers non-government organisations to intervene earlier and work with our young people to identify the early intervention services that they respond to in order to stop them from becoming addicted to drugs.
Expressions of interest for the grants will close on 28 November 2016.
Further information on the fund can be found at:

domain: news


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Track topics on Twitter Track topics that are important to you
Lamellar pores have superior biocompatibility due to their similarity to the lamellar structure of natural bones. In the present work, porous Ti6Al4V alloys with lamellar pores were successfully fabricated by directionally freeze casting. The lamellar structure/processing relationships were systematically studied through analyzing the interaction between ice front and alloy powders. The structural feature of translamella bridges is observed in the lamellar structure. The volume shrinkage of porous Ti6Al4V alloys is in the range of 44-60%. This is much higher compared with that of the porous ceramics. The solid content in the slurry exerts a strong influence on the porosity, while the freezing ice front velocity affects the structural wavelength and pore width. With the increase in ice front velocity, the structural wavelength decreases by an exponential function. The lamella formation mechanism and porosity gradient along the freezing direction were discussed. Young's modulus and yield stress of porous Ti6Al4V alloys fall in the range of 2-12 GPa and 40-300 MPa, respectively. The dominant compressive deformation mode is lamella buckling and splitting. The fabricated porous Ti6Al4V alloys possess higher relative yield stress.
This article was published in the following journal.
Name: Journal of the mechanical behavior of biomedical materials
A tri-stable structural switching between different polymorphisms is presented in 2D molecular assembly of 5-(benzyloxy)-isophthalic acid derivative (BIC-C12) at the liquid/solid interface. The assemb...
Microwave processing is a suitable technology for starch-based food processing. This work investigated the changes of structures and properties of high-amylose maize starch (HAMS) during short-time mi...
This paper investigates the effect of porosity and unit cell size variation in topology optimized (TOP) and selective laser melting (SLM) fabricated Ti6Al4V lattice structure on the mechanical propert...
This study examined the changes of water state and gel characteristics of Hairtail surimi during thermal processing including two steps. The results showed that there were four content of water in Hai...
Using a mixture of neutral primary amine dehydroabietylamine (DHAA) and long-chain cetyltrimethyl ammonium bromide (CTAB) as the template, ordered lamellar supermicroporous silicas were synthesized wi...
In addition to the physical, cognitive and psychological symptoms experienced by individuals with Multiple Sclerosis (MS), there is new research which indicates that some individuals with ...
The purpose of this research is to collect data on patients that had the Legion Porous HA Tibial Baseplates and/or the Legion Porous HA Femoral component implanted in the past. Smith & Nep...
Lamellar ichthyosis is a congenital disease of the skin with a generalized scaling. The primary activity of liarozole is considered to be the inhibition of the degradation of a substance c...
- The goals of this study are to develop a lyophilization method for anterior lamellar transplants in Brasil and to make a comparative analysis among patients transplanted with lyophilized...
The aim of the present study was to determine whether oral dosing, up to 9 grams/day, of porous silica administered as a food additive can be used safely in normal weight and obese male hu...
Numeric or quantitative entities, descriptions, properties, relationships, operations, and events.
The entities of matter and energy, and the processes, principles, properties, and relationships describing their nature and interactions.
The properties and relationships and biological processes that characterize the nature and function of the SKIN and its appendages.
Theoretical representations and constructs that describe or explain the structure and hierarchy of relationships and interactions within or between formal organizational entities or informal social groups.
Ecological and environmental entities, characteristics, properties, relationships and processes.
Arthroplasty Joint Disorders Orthopedics Spinal Cord Disorders Orthopedics is the science or practice of correcting deformities caused by disease or damage to the bones and joints of the skeleton. This specialized branch of surgery may ...
Stress is caused by your perception of situations around you and then the reaction of your body to them. The automatic stress response to unexpected events is known as 'fight or flight'. Discovered by Walter Cannon in 1932, it is the release of h...
Adhd Anorexia Depression Dyslexia Mental Health Psychiatry Schizophrenia Stress Mental health, although not being as obvious as physical health, is very important, causing great unhappiness to those affected, causing add...


CHATTANOOGA, Tenn. — With about a minute remaining Monday night against LSU, Monique Currie had the ball in her hands as her team’s Final Four chances were on the line.
Currie moved to the three-point line and froze. She pivoted desperately but was unable to come up with a play to help the Blue Devils cut into a six-point deficit.
Currie lost her dribble, and her second-seeded team lost its matchup with No. 1 seed LSU, 59-49, in the Chattanooga Regional Final.
“[LSU] did what they needed to do to win. They played tough defense and rebounded the basketball,” head coach Gail Goestenkors said. “They outrebounded us by 15 in the second half and that was the difference in the game.”
The Blue Devils (31-5) came out strong against the Tigers (33-2), holding the lead for most of opening 20 minutes. LSU would take the lead 15 seconds into the second half, and Duke held the lead for a total of just 38 seconds after the break.
Seimone Augustus, who was named Most Outstanding Player of the regional, scored a game-high 24 points, including 12 in the second half. Down the stretch, Augustus routinely served up key plays for the Tigers.
With 30 seconds to go and Duke down by seven, the unanimous All-American selection grabbed a rebound off an LSU miss from the line, giving her team a pivotal extra possession. Augustus then extended her team’s lead on two successful shots from the line, diminishing the Blue Devils’ hopes for a comeback.
The Blue Devils’ own All-American, Currie, rarely took comfortable shots as most of her attempts came in the form of off-balance looks from the perimeter.
With 53 seconds remaining, Currie stole the ball and missed a jumper at the other end, landing on the floor. Augustus lent a hand to the fallen Blue Devil and patted her on the back as the pair ran down the court for a LSU possession.
“I think we did an excellent job in the first half, not as much in the last five minutes of the game,” Currie said. “In the second half, we just got a little over-rotated. They were getting a lot of easy baskets in the second half. They took advantage of that.”
Currie has one more year of eligibility but has not decided whether she will return. After Monday night’s game she said that not winning a national championship will factor into her decision.
Duke did not miss Currie’s offense much early as its dominant low-post offense and tough defensive pressure established an early lead, which the Blue Devils maintained for most of the first half.
Under the basket, Mistie Williams secured strong positioning, leading the team with four first-half defensive rebounds and 13 first-half points, most coming on layups following passes from the top of the key. Williams was a perfect 7-for-7 on the night but did not score in the last 18 minutes.
The Tigers made a mental defensive adjustment in the second half, “cleaning up,” LSU head coach Pokey Chapman said. The shift stunted the Blue Devils’ offense, particularly passing access to Williams.
“They just really started fronting me, and then if I happened to push them up the lane, you had Sylvia Fowles ready to double me,” Williams said. “We just didn’t make the adjustments early enough.”
Sylvia Fowles, standing at 6-foot-5, provided a challenge for Williams, Alison Bales and Chante Black, who had 13 points and 11 rebounds, eight of which came on the defensive end.
In the second half, the Tigers overwhelmed Duke, shutting down their offense and driving through the defense that had been so effective through the first 20 minutes of play. LSU fought back on a four-minute 12-2 run at the end of the first half and carried its momentum into the second half.
Bales and Williams tried to gain position underneath, but four fouls hindered each player’s efforts, which shortened the Duke bench for much of the second half.
After shooting 52.2 percent in the first half, the Blue Devils could only make a quarter of their shots fall after the break. Without Bales and Williams, many of those shots came from long range, where Duke looked considerably less comfortable.
“I thought we were in great position. We were playing excellent defense, and we had the tempo we wanted,” Goestenkors said. “I think fatigue was a factor. We need our rotation.”
To Goestenkors, this year’s achievements were remarkable for a team that faced much adversity in the form of injuries, suspensions and graduated stars. But after the team’s final game, the head coach was frustrated with how the loss came down to rebounding and turnovers.
The Tigers outrebounded Goestenkors’ squad by 15, after the teams each had 14 boards in the first half. LSU scored 17 points to Duke’s six off turnovers.
“What’s disappointing is that I think the game came down to things that we could have controlled,” Goestenkors said.
No. 7 seed North Carolina fell to Baylor in the other regional final Monday.... LSU will take on Baylor in the Final Four.... Duke’s 19 points in the second half were a season low.
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Petros Koublis is a Greek photographer who works as freelance since 2004, cooperating with major Greek magazines and published in national and international press. The images of his In Landscapes project were made around the outskirts of Athens, less than 30 miles away from the heart of the capital. It is the area that surrounds the depressed city and all the millions of its citizens’ individual stories. Outside the invisible borders of the extended metropolitan area, in the land that lies past the edge of the city, time seems to move parallel but in a different density. There is an inevitable contrast between the two states, a parable manifested by the discreet mystery that trees seem to hide among their branches and seas among their waves. This is an alternate state in parallel time, where silence seems to carry inside it a waiting, patiently whispering a long forgotten language.
I worked on a series of images that were aiming to express this undefined, mystical presence that wanders around these areas, a lost connection between us and a beauty that regardless of its obvious magnificence it always remains far, strange and unfamiliar, hidden behind an unreasonable mystery. For it’s not only nature, eventually it is beauty itself that has lost its intimate character, overtaken by the values of an artificial illusion that’s reflected through our collapsing cities.
Text and images © Petros Koublis


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General Counsel & Chief Compliance Officer
Kristen Howell brings more than twenty years of legal experience in FinTech, corporate securities, and financial services.
Prior to joining CrowdStreet, Kristen was a partner at Am Law 100 law firm Fox Rothschild, LLP, where she lead the firm’s national investment funds practice. Kristen previously served as General Counsel for a registered investment adviser with $19B in assets under management and six publicly traded mutual funds. Kristen has been featured on NPR – Marketplace Tech and InsideCounsel, been quoted in Law 360 and other publications, and has spoken widely on FinTech, investments and crowdfunding.
Kristen holds a BS in Political Science from Texas Christian University and a JD from The University of Colorado School of Law in Boulder.

domain: law


text:
Below the town of Tivoli, on peaceful hills lies the residence of Emperor Hadrian from the second century. Hadrian, who was an emperor interested in arts and culture, the residence was designed to be a park with buildings referring to his favorite works of Greek and Roman architecture, and even Egyptian. The whole thing is gigantic – starting from the area on which it stretches to the individual vaults, which as if in spite of their size and large holes punctured by a tooth of time, hold up. The huge dark clouds over us matched perfectly with these spaces.
(with Kasia, May 2019)

domain: geography


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Exarhia – my neighborhood – is a small area in Athens’ inner city where people, ideas, and practices outside the system strike root and grow. People will gather here to discuss and protest, to attend events and assemblies at social centers and squats.
In all of Greece, Exarchia is also the one area under the most stringent police occupation. For as long as I can remember, armed officers, many carrying automatic rifles and shields, patrol the streets on foot, on motorcycles, in cars, arresting people, throwing them in lockups, beating them up. They spray tear gas at the drop of a hat.
Before the elections, Syriza promised to withdraw the patrol wagons and the police special forces units stationed in the area. And indeed, Syriza kept their promises: the heavily armed police forces were moved 200m-300m away! Typically they are not in Exarhia anymore. A few days ago, when a police car was set on fire, the special forces once again invaded the neighborhood, randomly beating up and arresting residents and passers-by. As his predecessors had done so many times in the past, Giannis (Yannis) Panoussis, the new Minister of Public Order, didn’t even place the incident under investigation. http://www.tovima.gr/en/article/?aid=677593
Panoussis recently stated that the immigrant detention centers – which are, in fact, concentration camps where thousands of immigrants are kept locked up for up to 18 months without having committed any crime – will become “hospitality centers,” a euphemism the previous government used as well. Syriza will give a humanitarian touch to the State of Emergency and will dress it with a social-democratic cloak. The concentration camps may still operate, but the NGOs that will be involved will increase in number and will send more blankets and sandwiches by way of charity, along with social workers. Issues like the drowning of refugees from the Near and Middle East in the Aegean Sea and the slave labor conditions for migrant workers are not priorities for the new government. People who share anti-nationalist views have been silenced and Syriza hurries to set up its own “patriotic alliance”. http://www.wsws.org/en/articles/2015/01/24/syri-j24.html
In any case, there are MPs and party officials in Syriza who have more than instrumental relations with the far right. And we shouldn’t forget that Syriza has formed a government with Independent Greeks, a small party which is deeply xenophobic and homophobic.
Despite the tough competition from Independent Greeks, the place of the neo-Nazi Golden Dawn party is stable – it came third in the elections even without the promotion it enjoyed two years ago by the mainstream media; even though its leadership is imprisoned. But, it would be a mistake to consider racism a Golden Dawn privilege – especially when racism and nationalism have been incorporated for decades in the official policies of the State. In fact, they have been a central political choice of the Greek State for more than a century. Since the end of the dictatorship in 1974, the far right has been more or less assimilated in New Democracy, one of the major parties in Greece that led the government coalition in the last three years, and recently in smaller parties like Independent Greeks. Their populist, anti-immigrant rhetoric and agenda found a breeding ground in a majorly conservative and xenophobic society.
Actually, the whole political spectrum in Greece has moved right to appeal to the nationalist demands of the majority of the electorate. The success of Syriza drew mainly on the disaffection of the working and lower middle class voters to the politics of the pro-Memorandum governments. In the five years since the agreement was signed, the Greek working class have seen their incomes dwindle, and have been forced to accept low-wage and insecure jobs, while unemployment climbed to 27%.
At the same time, economic depression transformed the great majority of the petite bourgeoisie into proletarians. More importantly, it thwarted their desire for social mobility – for them and their children.
Now they long for a return to the traditional form of the Nation State, which will protect them from the economic hardships of the crisis. All in all, they have political and economic interests linked to the newly elected government, as they hope that Syriza will restore their dream of climbing up the social hierarchy. This is rational from the viewpoint of petite bourgeoisie and typically opportunistic. Syriza –the “patriotic” Left– promised to revive the State to the function it served so well in the past: a structural mediation whose purpose is the protection of its citizens from the “bad markets” and the “evil forces” of the global economy.
In a country where the crisis is blamed on the “bad Europeans” and/or the “supranational elites”, where the interference of Germany is used as an excuse to call Greece an “occupied territory”, and where resistance to austerity is understood as a revival of the anti-fascist struggles of the 1940s, the majority see the State as responsible for restoring national sovereignty against foreign lenders and institutions, especially Germany.
Besides that, Syriza has managed to recuperate the anti-austerity struggles and the demands of the squares’ movement (as the anti-austerity movement is known, its public protests often occurring in public squares). Having become the main opposition during a time of increasing political action, they did their best to divert energy from the streets back into parliamentary politics. Actually they waited two and a half years for the government to fall.
The ruling class now hopes that Syriza can restore politics as a legitimate source of consensus, soothe the protests and divert people’s attention from the capitalist crisis and the transnational commercial war. In a time when the Greek capitalism has gone bankrupt, social peace can guarantee the unimpeded continuation of capital accumulation and the survival of Greek capitalism at the expense of the working class.
While the fundamental social relations of class exploitation stay intact, nationalism remains a la mode in Greece. Pro-government demonstrations are held to back up the patriotic discourse and political agenda of Syriza. The crowd demands a more present and more aggressive Greek State. They’re waiting for a leader who will put an end to national dependence and will unite the nation under a common cause. Of course defending the national sovereignty requires sacrifices. Once again in its history, Greek capitalism will use the geopolitical position of the Greek State as a tool for its survival. Contrary to the crowd that gathers outside the parliament, the capitalists know that national independence is achieved by the barrel of a gun both within and outside the country. And this gun is put on the temple of the multinational subversive proletariat.
Jazra Khaleed was born in 1979 in Grozny, Chechnya. He lives in Athens’ inner city and writes poetry in Greek. He edits the literary magazine Teflon. His poems have appeared in World Literature Today, Modern Poetry in Translation, Westerly and Die Horen. His poem “Words” appeared in the anthology With Our Eyes Wide Open: Poems of the New American Century. A boxer as well as poet, he is co-publisher and editor of Topovoros Books, a small publishing house located in Exarchia, Athens.


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As of July 1, 2016, all-terrain vehicles (ATVs) are allowed to ride on the highways in Rocky Top, TN.
Why is this so important? Because Rocky Top is adjacent to Windrock Park, which is the largest privately-owned off-road recreation area in the country with over 72,000 acres that includes off-highway vehicle trails, hiking trails and mountain biking trails.
Having access to the highways in Rocky Top will allow riders to come into town from the Windrock Park trails to buy gas, eat at restaurants, stay at the hotels, etc. without having to reload their equipment.
What to know before you go. Riders must have a Windrock Park permit to ride on Windrock property. The permits are sold online here. You can also purchase permits at Coal Creek General Store, located at 331 S. Main Street in Rocky Top.
Don’t pass by the local eateries. If you love to experience where the locals eat, be sure to stop in the Vols Diner to grab a bite to eat. They are open for breakfast, lunch and dinner and offer a wide variety of delicious meals. Nanny’s Kitchen is located near the interstate and serves pizza and home cooked meals. If you’d rather grab something to go, you have to try a famous Bologna sandwich from Coal Creek General Store. If you are looking for the familiar, there is a Cracker Barrel in town.
There are a few rules to ensure the safety of the riders and other users of the roads.
All-terrain vehicles will ONLY be allowed on Highway 25W from the intersection of Colonial Lane to the intersection at Jacksboro Avenue, Highway 116 from the intersection of Highway 25W and Beech Grove Road and on Beech Grove Road from the intersection with Highway 116 to the entrance to Windrock Park and only between one-half (1/2) hour after sunrise and one-half (1/2) hour before sunset. The route is marked with signage. CLICK HERE FOR A MAP.
Anyone operating an ATV must be 16 years of age or older and have a valid driver’s license.
Each person riding on the vehicle must wear a helmet.
The vehicle must have working headlights and brake lights. If the vehicle doesn’t have turn signals, the operator must use hand signals when turning.
The owner of the vehicle must have insurance on the vehicle and must be prepared to show proof of insurance.
Riders must lawfully operate their vehicle at all times.
Any violation to the state laws and the rules listed here will result in loss of privileges to operate vehicle on the specified road.


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NEWPORT BEACH, Calif., June 28, 2018 /PRNewswire/ — With the rise of digital technology, access to whatever our hearts desire has become nearly instantaneous. It allows us to connect, for the cost of an Internet connection, with old friends and acquaintances – anytime and from virtually anywhere. While the positives are clear to see, a darker picture is starting to take shape: the rise of so-called ‘cyber affairs’.
So, what’s behind the growth of these digital dalliances? Author and speaker Tina Konkin, who has witnessed the phenomenon first-hand through her acclaimed Newport Beach, California-based counseling program, Relationship Lifeline, says one need to look no farther than interactions on social media or the worldwide web.
A 2010 survey by the American Academy of Matrimonial Lawyers (AAML) found that four out of five lawyers used evidence derived from social networking sites in divorce cases. In addition, it’s estimated that 1 in 5 divorces today have a direct correlation to amorous encounters and relationships cultivated online.
“The allure of cyber affairs for many is the minimal effort needed to engage,” said Ms. Konkin. “More often than not, we’re seeing these cyber affairs stem from a reconnection with people in their past, where individuals are essentially transported back in time and start to form a romantic bond through past experiences they’ve shared. Unfortunately, I’ve experienced it myself.“
Another driver of digital infidelity: the casual attitude and easy access to pornography. According to a survey published in the Journal of the American Psychological Association, 86% of men are likely to click on Internet sex sites if given the opportunity. Furthermore, according to an AAML poll of 350 divorce attorneys, two-thirds reported that the Internet played a significant role in break-ups. More than half of those cases involved an excessive interest in online porn.
“The overwhelming number of pornographic websites and chat rooms have played a significant role in disrupting the exclusivity of human sexuality,” said Ms. Konkin. “The low barrier of entry allows individuals to get what they want, when they want it. It’s become Pandora’s Box.”
Although the conversation surrounding ‘cyber affairs’ may be uncomfortable for some, the world-renowned couples relationship expert maintains that such dialogue is necessary because of the threats they pose to long-term happiness and growth. By raising awareness around the issue, she hopes to be a catalyst for those conversations and help people recognize these online encounters for what they are – affairs.
About Relationship Lifeline
Founded in 1993 by Ron and Tina Konkin, Relationship Lifeline provides healing, hope, and transformation for marriages and family relationships. Through a series of condensed, engaging exercises, participants learn how to create positive, lasting change that repair and save breaking relationships.
CONTACT: Michael Corbett
SOURCE Relationship Lifeline

domain: sociology


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What's 100x Leveraged BTC Futures Trading?
In financial trading, the use of leverage can multiply your profit, while you have to assume bigger risk of loss at the same time. Bexplus leverage trading is a derivative financial instrument of financial trading. Bexplus users can enlarge their tradable assets with the leverage on the platform, and thus enjoy bigger profit on investment. But they have to bear the correspondingly high risk at the meantime.
First, what is BTC margin trading?
Margin trading is to enter larger trade with small amount of BTC investing in, in a bid to multiply the profit. But at the meantime, you have to take multiplied risk of loss. Since Bitcoin has huge price fluctuations, you ought to have a full understanding of the risk of margin trading before you trade it.
Second, when the price of BTC is expected to rise, how to maximize profit with leverage trading?
With BTC/USDT as an example, Bexplus offers up to 100 times leverage to investors. That is, if you buy up, you can get 100% profit with 1% price rising.
Three, when the price of coins is expected to fall, how to make money by short selling?
With BTC/USDT as an example, Bexplus offers up to 100 times leverage to investors. That is, if you buy down, you can get 100% profit from 1% price decrease.
You can gain profits no matter the price goes up or down.
Four, what is the risk of 100x leverage margin trading?
Leverage makes it possible to gain larger profit with small capital. But if you bet on the wrong direction, the loss will also be magnified in equal proportion. Thus, traders ought to be aware of the risks and control positions well.
Five, how to lower the risk of leverage?
1.Appropriately take advantage of leverage times, and control position sizes.
2.Timely stop loss and take profit, and spontaneously close the position.
3.Timely add margin to ensure the ratio of total assets / leverage limit exceeds 110%.

domain: finance


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Hello, I'm Ronke Edoho. Welcome to my food blog. 9jafoodie features Nigerian food recipes, health and cooking tips. I hope to inspire other home cooks like myself to make wonderful dishes. Explore, leave a comment if you have any question 🙂 Learn more
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For people looking for healthy fuss-free breakfast options breakfast overnight oats is my go-to. I typically prep on Sunday and keep in the fridge for grab & go breakfast throughout the week. This recipe makes [...]

domain: food


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- The Enterprise
- The Recorder
The study to enlarge the Gov. Thomas Johnson Memorial Bridge over the Patuxent River is just about finished. Now comes the hard part finding the $750 million or more to build it.
The Maryland State Highway Administration briefed the St. Mary’s County commissioners on June 28 on the planning status and asked for the board’s preferences on options to expand the bridge and to fix the intersection at Route 235 and Route 4.
The state funded $5.5 million for the project’s planning, said Jeremy Beck, project manager, but noted “this project is not currently funded beyond project planning.” There are still the final design, right-of-way acquisition and construction phases to go.
The state’s estimate is still $750 million for the entire project.
Options include building a new second span parallel to the existing bridge. The existing span would carry two lanes of traffic southbound and a new span would carry two lanes northbound with an additional 10-foot lane for pedestrians and bicyclists.
Another option would be to construct an entirely new bridge with four lanes for vehicles, with a lane for pedestrians and cyclists, and then tear down the existing bridge. An entirely new span would be 7,310 feet long, Beck said.
The St. Mary’s commissioners had no unified opinion last week, but in interviews June 29, three of them agreed any new span should be tall enough to allow large ships access underneath in the future.
The current span at its highest point is 140 feet above the river’s channel, which is 130 feet deep. The Navy wanted the bridge built that high in 1969 during design to allow its ships to anchor at the base’s Solomons annex. Ships aren’t moored there anymore since the Navy pier burned up a few years ago, but the area remains a deep-water port. A commercial port was once proposed at today’s Myrtle Point Park in California, Md.
Beck said federal officials are comfortable with any new bridge at least 70 feet tall. “Lowering the bridge would potentially reduce costs,” he said. “They do not need that height anymore,” he said of the Navy.
“If you’re going to spend a billion dollars-plus, why shortchange yourself?,” said St. Mary’s Commission President Jack Russell (D) on June 29. “I think we ought to put a bridge back that will replicate the one we have now.”
“We probably need to keep the height as it is for the Solomons annex,” said St. Mary’s Commissioner Larry Jarboe (R) on June 29. “It would be a logical place in the future with federal support for cruise ships running out of Solomons,” he said. He said he didn’t have much of a preference between adding a second span or building an entirely new one. “Regardless of which way you do it keep the height,” he said.
St. Mary’s Commissioner Todd Morgan (R) said June 29, “70 [feet], I don’t think works. We have that deep-water channel there. You don’t want to ruin opportunity economically on either side of the bridge.”
On the Calvert end, Calvert County Commissioners’ President Susan Shaw (R) said she believes the best approach is to marry what the public has said it wants to see and SHA’s studies, since Sen. Roy Dyson (D-Calvert, Charles, St. Mary’s) has said the current span is unsafe because of the additional traffic it bears. State highway officials have said it is safe, however.
“Before I would ever make a recommendation I would need to hear from state highway what the longevity of that bridge is,” Shaw said.
The current height is a stunning visual landmark, she said, but the height is no longer required by the U.S. Navy for the ships to go underneath. “So then it comes down to the fact that it is a lot more expensive to build a new bridge at the same height as the old bridge versus the additional justification of its being a stunning visual marker,” she said. “That’s the kind of thinking that should be going on.”
Fellow Calvert Commissioner Gerald W. “Jerry” Clark (R) said he believes the option that has been most embraced in the county is the construction of a new four-lane bridge, with additional space for bikers and pedestrians.
“One thing I didn’t want to see is one bridge parallel beside it so you have one higher and one lower,” Clark said, adding that he doesn’t know if it’s necessary to build the new bridge as high as it is now because boats will still be able to sail underneath it at a lower height.
“It could be much, much lower,” Commissioner Evan Slaughenhoupt (R) said. “But I also understand there is currently a nice view of Solomons when you’re up there. The lower you go, the lesser the nice view.”
Slaughenhoupt said Solomons residents have expressed concern over the possibility of building a second span. “If they build another span and the existing one remains, it should stay at the same height, otherwise it’ll look ugly,” he said.
The State Highway Administration will produce its preferred bridge alternatives this fall and the location and design approval is scheduled for the spring of 2012, Beck said.
There are three options for the intersection of Route 235 and Route 4, the busiest intersection in St. Mary’s County with between 40,000 and 55,000 vehicles a day using it. One option would allow a constant flow, another would build a ramp from Route 4 to southbound Route 235 and another would build an urban intersection where Route 4 would cross underneath Route 235.
“We want to have traffic ease in St. Mary’s County to maximize our transportation system,” Russell said, though he does not have a preference on what kind of intersection goes in.
He said of the entire project, “It’s going to cost a tremendous amount of money ... which we don’t have now.”
Jarboe said of the intersection designs, “Let’s see what they come up with as the safest.”
Morgan said he had no preference, but said he didn’t want to see “a mixing-bowl design,” like the kinds found in Northern Virginia.
The Gov. Thomas Johnson Memorial bridge opened in December 1977 at a cost of $26 million then. It was estimated to cost $10.6 million in 1966 when the project was approved.


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THE D'OYLY CARTE OPERA COMPANY
(Mr.) Parr (1880)
From February to July 1880, a Mr. Parr toured North America as Samuel in The Pirates of Penzance with D'Oyly Carte's Third American Pirates Company.
He may have been Charles T. Parr who had several appearances in New York comic operas and burlesques between 1882 and 1885, and appeared again briefly in 1905-06.
|Page created March 28, 2003||© 2003 David Stone|

domain: entertainment


Will Apple Launch a Smart Watch?DCI
Reports reveal that Apple and Intel are working together for the release of iWatch in 2013.
iWatch is expected to be a bluetooth-enabled watch with a 1.5-inch OLED screen. People will be able to send messages, email and use Facebook using iWatch. Users will also be able to communicate with their iPhone and other devices using Bluetooth.
There have always been rumors about Apple and its devices. Long before Apple revealed its latest iPhones and iPads to the public, people knew almost exactly what they would look like and what kind of features they would have. Similar sources are speculating about the new iWatch says Business Insider.
Sources also claim that ‘wearable computing’ is a well-known concept for futurists. Apple might eventually join the league says analyst Gene Munster. Apple is spending billions of dollars on projects that no one outside the company knows about. It is speculated that Intel came up with the concept and Apple is now “interested” in implementing it. There are debates if Apple’s current iOS devices that use microchip designs from ARM will switch to Intel.
In recent years, Apple seems to be the world’s most valuable company, and it conquers its own product lines. The iPhones overtook iPods, and now iPads are replacing Mac desktops and laptops. Eventually, Apple has found out a way to replace its smartphones with this new iWatch.


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With guests coming and going over the holiday, it’s nice to have a little to nibble on before the main event. Why not create a beautiful table spread for your guests to graze this year! This cheese plate was easy to pull together simply using my existing cutting boards and Scotch™ Expressions™ Tape. The chalkboard tape is such an awesome product! You can use it to create a pattern and label the goodies you have laid out so everyone knows just what they’re getting.
I am loving the deep bold hues for fall this year, and I’ll take purple and gold over orange any day!
To learn how to recreate this cutting board visit the Scotch® Brand Style Blog for the full tutorial. Don’t forget to share your creations using the hashtag #scotchstyle , we want to see what you’ve come up with!
this is a sponsored post, the design styling and and opinions are my own. email email@example.com for inquiries

domain: design


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This season saw a ton of new shows tough it out in primetime. Now that it’s been a few weeks, we can finally judge which shows succeeded, which bombed, and which need to be put out of their misery.
There were so many new shows, not even I could check them all out. There’s only so much one person can handle! So while many shows will be mentioned here, please share your thoughts.
Revenge: This soapy melodrama is the best new show of the fall tv season. It’s bad things happening to bad people, and with all the economic unrest currently going on in the states, it couldn’t be more perfectly timed. While Emily is among the ridiculously wealthy, the audience gets to see her take down her villianous neighbors one by one. While the formula of a “revenge-a-week” was starting to get too predictable, they managed to switch it up just in time by having a wrench thrown in Emily’s well laid out plan. While the show started with a murder, and therefore we know what will come in a few more episodes, it’s been great ride to see just how we get there. The bigger mystery is how the show will function after it reaches the murder that kicked off the show. Where will it go from there to fill in the 22 episode order? While I don’t know the answer, I’m definitely going to be tuning in to find out. Verdict: Success
New Girl: This “adorkable” show rests completely on the likability and charm of its star Zooey Deschenel. Fans familiar with her work in the very twee indie duo She & Him, and her role in (500) DAYS OF SUMMER won’t be surprised. The show got off to a bit of a rocky start with the roommate change when Damon Wayans Jr.’s show Happy Endings was picked up for another season, meaning his character from the pilot had to be written out abruptly. Most shows would have simply reshot his pilot scenes with a new actor, but for some reason New Girl decided to switch one black character out for another. Wayans’ Coach character was the most likable of the roommates, so it’s been an uphill battle for the new roommate. While the show has been off-air most of October, it was just starting to find it’s footing. Hopefully the new episodes in November pick up right where the last one left off. Verdict: Success
2 Broke Girls: The pilot was rough, but had potential to explore the classic “odd couple” story trope in a modern way. However, the more episodes they aired, each one kept aiming at a lower and lower common denominator in the humor. When the biggest jokes are about horse droppings, you know the show is trouble. The only comedy worse than this that hasn’t been cancelled yet is Whitney, and unsurprisingly they were both created by “comedianne” Whitney Cummings. Verdict: Disappointment
Terra Nova: One of the most expensive and longest gestating pilots of the fall season, Terra Nova did have some impressive moments in the first few episodes. There were scenes that felt straight out of a movie in terms of scope and effects. However, those moments are few and far between, and no matter how much money they spend on effects that won’t fix some very basic flaws in the script and characters. For a story about dinosaurs and time travel, I found myself bored and unmotivated to tune in every week. Verdict: Disappointment
The Secret Circle: The new supernatural teen angst show on The CW is a perfect companion to its lead in, The Vampire Diaries. However, it’s definitely still suffering from growing pains and identity issues and it tries to juggle the teen storyline and the adult/overarching town mystery. The first few episodes focused too heavily on the teens for me, but now that the grandmother is in the loop I’m hoping for a big push of the adult plotline. Even with the “who’s sleeping with who” hubbub, there’s enough quality mystery there to keep my invested in at least a few more episodes. Verdict: Success
Hart of Dixie: Another CW show, this harkens back to the network’s WB roots like Gilmore Girls and Everwood. It’s a bit more wholesome and traditional than the other new CW shows, telling the simple story of a young New York, big-city doctor as a fish-out-of-water in Bluebell, Alabama. Rachel Bilson is her adorable self, and the supporting cast has enough talent to make you chuckle, care about their antics, and want them to all warm to Bilson’s Dr. Zoe Hart. Verdict: Success
Pan Am: Another very expensive pilot, this was all flash and no substance. The 60s atmosphere was well executed, but there’s only so much you can do with boring characters and a pointless pilot. While this debuted to strong numbers, I’m not surprised at the huge dive it’s taken in the ratings. I don’t expect this one to survive on the schedule much longer. Verdict: Disappointment
Ringer: While this was Sarah Michelle Gellar’s big return to television, I can’t behind this show even as a major Buffy fan. The acting was wooden, the characters are completely unlikable, and the melodrama just didn’t live up to the promise. For being SMG’s monumental return to television since Buffy ended in 2003, plus it’s CBS production, raised expectations and hype for The CW show and it just couldn’t attain it. The pilot was so dreadfully boring that many did not return. Luckily for it’s fans, the ratings and press were enough for a back 9 episode order to produce an entire season. Verdict: Disappointment
Once Upon A Time: One of the last new fall shows to premiere, this had amazing talent behind it. Film actress Ginnifer Goodwin, Lost writers, and stories that nearly everyone on the planet is familar with - the stakes were high. After the premiere this week, I must stay it was a disappointing start. The characters were flat and boring, particularly in the fairytale world. Without engaging characters, the fantastical stories in both the fairy and real world are going to fall flat. It’s hard to say how this show will be play out down the road - how the worlds will run parallel, how Emma will interact with the fairytale world, and so much more. With only one episode having aired, it may be too early to judge if this show will be a disappointment or success. Verdict: Pending
Lastly, since the season has been underway for several weeks now, there have already been a number of casualties. Cancelled shows are piling up, including Playboy Club, Free Agents, Charlies’ Angels, H8R, and How to Be a Gentleman. Verdict: Bombs
Have you checked out any of the new shows this season? Let us know your thoughts in the comments!


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Oct. 23, 2012 - Climate Summary for the latest growing season (April through September) in North Dakota is now available. On the average, the growing season of 2012 in North Dakota was the 8th warmest and the 13th driest growing season among the last 118 years of North Dakota's climatological history since 1895.
The report also includes:
- Temperature and precipitation rankings, and the growing season length rankings for ND as well as six major cities in ND
- Drought timeline
- How ND escaped what could have been the worst drought to hit ND since 1988
- 2013 outlook
Sept. 26, 2012 - USDA Designates 4 Additional Counties in North Dakota as Primary Natural Disaster Areas. Counties include: Benson, Billings, Eddy and Ramsey.
Sept. 14., 2012 - Quarterly North Dakota Climate Bulletin for Summer 2012 (PDF)
Includes weather highlights, graphics, Fall 2012 Outlook and more.
Sept. 12, 2012 - USDA Designates 7 Counties in North Dakota as Primary Natural Disaster Areas With Assistance to Producers in Surrounding States Counties include: Bowman, Dickey, Golden Valley, LaMoure, Ransom, Slope and Stutsman.
Sept. 5, 2012 - USDA Designates 7 Counties in North Dakota as Primary Natural Disaster Areas With Assistance to Producers in Minnesota Counties include: Barnes, Cass, Grand Forks, Griggs, Nelson, Steele and Traill.
Sept. 4, 2012 - North Dakota State Climatologist Dr. F. Adnan Akyuz says 17 counties in North Dakota are in severe drought.


Whilst putting together this post, I ran through Piskie Sits’s EP The Way I’d Like To Go a few times, mentally ticking off what I fancy about the band. What strikes me most about the Wakey group is their seamless marriage of Americana and ’90s indie rock, something that the Idaho-based Built to Spill has always done quite well. This is definitely Perfect From Now On for a new millennia.
With a live resume that includes support for the likes of The Fall, Nine Black Alps, Times New Viking, The Research, Frightened Rabbit, Envelopes, and Wild Beasts, the band has several releases under their belt, including and an album entitled The Secret Sickness and a split EP with the Spills. They’re currently rehearsing with a slightly revised line up, amassing more new material for future releases and their set this spring at Long Division.


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Alva H. Claxton
Found in 3 Collections and/or Records:
The letter contains information on the church history in Busti, New York beginning in 1937 with the Mission Covenant Church. A house property was purchased in 1940 and converted into a church with a dedication held on September 14th, 1940. The letter also contains information on Camp Goodwill.
Bengtson found CHOG through reading material published by the Swedish Gospel Trumpet. The church began as a Sunday school, revivals were conducted and building lots were given to church.
Letter contains a few facts on the Church in South Haven. Sunday school was organized in 1922, with preaching services conducted in the old people's homes on Monroe blvd.

domain: library


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We celebrate with a very enthusiasm, pride and enthusiasm on the occasion of Republic Day every year. These days are very important from the Indian perspective for every citizen. On the day of our country, we are celebrated the republic of the day.
About 3 years after the independence of India (January 26, 1950) we became a summosphere, secular and democratic, republic. The total time in making Indian constitution was 2-year, 11-month, 18-day, in which there is a description of all security rights from fundamental rights.
Today, the Constitution was formally adopted, our constitution has been written in the biggest and accurate way in the world, first of all, Mahatma Gandhi was also contributing with Dr. Bhimrao Ambedkar ji with Dr. Bhimrao Ambedkar ji.
History of Republic Day
On August 15, on August 15, when our country was completely freedom to the country, the rule of law or saying to run our country was the strict need of the constitution. To run India, there were no special and political facts that could run a whole country well.
However, in 1935, in 1935, according to the Act of the Government of India was originally ruled by ruling. But this act was a major lean towards the colonial rule, thinking about this, our India country, the then political party decided that a special constitution which is in the interest of India and its guidance improve the future of the country.
Our great man to complete the work of the Constitution led by Dr. Bhim Rao Ambedkar in August 28, 1947, and later it was presented by this Constitution Committee on November 4, 1947. Although its process was very long, it took 166 days to be completed. Apart from this, all the sessions in the event of this committee were also open to the public. This constitution was clearly clear that the people had to balance the objectives, in which all Indian citizens could get equal rights related to their religion, culture, caste, gender etc.
When the functioning of this constitution was completed, it was officially presented in front of the country in the form of Indian Constitution in January 26, 1950.
Since then on 26th January is celebrated as “Republic Day”. The British rule ended, which has the origin of a new morning for all the Indians.
Republic Day Maha Parv
Republic Day is represented by respect and integrity of the country by singing the nationality and integrity of the country by singing the Republic Day, together with respect and honor in one door, with respect and honor in one door. By taking Mahaparv on the red hand, the parade is done till India Gate, in which all the defense and security personnel of India are organized.
On that day the flag is done by the Hon’ble President, the wonderful scene is seen by the Army, Navsena, Air Force, participating in the parade on this day, along with the entire world, the whole world’s eyes were seen to see the bravery and power of India. It is, along with all the states of India are extracted which every state reflects its sovereignty and civilization.
In Alva Vidyalaya, the colorful program is also done on the Republic Day in its own way, in which all students reflect by the performance of their art program in which (songs, music, drama etc.).
Republic Day Celebration
In our country, people celebrate with great enthusiasm and happiness on 26th January. On this particular day, the people celebrate together with each other and forgetting religion, caste, discrimination together.
If this is said, then our India reflects unity in diversity. On 26th January, the capital of India is celebrated with the Parade in New Delhi. This special day displays the power of Indian Army and the cultural civilization of India with Indianism in Parade. 21 guns salute are also given after the national anthem.
During this 26th January, in every city of every state, people are national anticipation on the occasion of Republic Day, after that the tricolor flag is hoisted in respect of our country. After this, after hoisting the flag, our freedom fighters are saluted by remembering, which has sacrificed the country to free.
This day is a very proud day for Indian people. On this day, the child participates in the schools in schools. They take care of their form as their ideal freedom fighters. The children who perform well in many schools are honored.
Importance of January 26
India is considered to be very great importance in the country on 26th January. In 1929, a proposal was passed by the Congress in Lahore on December 29, which was declared by the Congress convention, full Swaraj i.e. the complete independence seeking the upcoming goal of India.
Looking at the future of India at that time it was decided that on January 26, the whole India country should be celebrated as Swaraj Day. Then on 26 January 1930, he was celebrated as Independence Day for the first time. Since then, he was celebrated similarly by 1947 and after going, our India country has been recognized as the Day of Technology Day from August 15, 1947.
However, due to the Republic Day due to the republic of India on 26th January, the new constitution of India was also announced.
In our India country, this Republic Day i.e. on 26th January, it is celebrated with great fanfare and brother fodder. On the occasion of this Republic Day, we remember all the freedom fighters and are encouraged to demonstrate their pride with patriotism to all citizens.
We should never forget the struggle of freedom to the people who worked forward to pursue the country. This should help us to take further the future of India with celebration.

domain: history


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Here's how long it takes to get over a broken heart
Your entire world falls apart with a breakup.
But you’ll get over it. It just takes some time.
According to a new study published in the Journal of Positive Psychology, people need about three months (or 11 weeks) to get over a relationship. The study asked 155 young adults when they first started to see the positive aspects of their relationship after the breakup. And in most cases, that came after three or so months.
The three-month buffer zone applied to both those who did the dumping, and those who were broken up with by their loved one, according to the study.
“This may seem too short to some and too long to others. Remember, it’s just an average — everyone heals differently,” wrote Nicole Weaver for Psych Central. “While you might assume the one breaking things off is in a better position than the one who’s kicked to the curb, it’s not always the case."
Most people in the study said they felt more goal-oriented and had become a better person after the time had passed. According to the American Psychological Association, these are positive signs of getting over a breakup. Feeling happier and more confident helps people avoid alcohol and drug abuse issues, which are often troubles people face when their relationships end.
But maybe there is no cure for a broken heart. According to a study from the University of Aberdeen, there isn’t a conclusive cure for “broken heart syndrome,” which happens when your heart goes under major stress or a traumatic event, like a bad marriage, according to Deseret News National’s Lois Collins.
Herb Scribner, Deseret News
Email: email@example.com Twitter: @herbscribner

domain: psychology


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One person was sent to a hospital after an 18-wheeler crashed into a bridge over Interstate 30 in East Dallas Wednesday morning, officials say.[[460721973,R]]
According to police, a flatbed rig hauling another truck was heading westbound on I-30 when a portion of the trailer crashed into a support beam for the St. Francis Avenue bridge at about 4 a.m.
Early reports indicated one person was transported to a hospital with undisclosed injuries.
The latest news from around North Texas.
The St. Francis bridge was closed as inspectors investigated the damage. I-30 was reduced to one lane as crews cleared the damage.
Check back for updates on this developing story.


wear resistant steel plate wear plate with hardness 360hb-55
wear resistant steel plate wear plate with hardness 360hb-55
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Wear Resistant Steel Plates - Wear Resistant Steel ...Wear Resistant Steel Plates Offering you a complete choice of products which include wear resistant steel - hardox 400, abrex 400 plates, wear resistant steel - hardox 600, wear resistant steel, abrex 400 and tiscral tata make 200bhn hardness wear liner plate sail hard.
The Brinell hardness is determined according to DIN EN ISO 6506. The hardness is measured approx. 1 mm beneath the surface of the plate. A core hardness of 90% of the mini-mum hardness is guaranteed for XAR ® HT, 400, 450, 500 and 600. The core hardness is calculated as the average of three measurements in the area of the centre of the plate.File Size: 524KBPage Count: 9What is wear resistant steel?The high abrasion resistance of Wear Resistant Steel - XAR 600 results from a unique water quenching process. This steel is extensively demanded in the market for their extreme wear stresses. Offered range of Xar 600 ensures easily welding functions. Corrosion to resistance Mining and earth-moving machinerySee all results for this questionWhat is abrasion resistant steel plate?Abrasion resistant steel plate is extremely durable and wear-resistant, defending well against scuffs and scratches. This type of steel works well in harsh applications, and also offers some impact resistance. Wear resistant steel plate will ultimately help extend the life of your applications and reduce your costs in the long-run.See all results for this question
Hardox® wear plate from SSAB is through-hardened steel that delivers better performance than other steels that are only surface hardened. Through-hardened steel undergoes a heat treatment in which the steel is exposed to high-temperature heating followed by controlled cooling.See all results for this questionWhat is AR500 wear plate?Applications may include use in mining, quarries, bulk material handling, steel mills, and pulp & paper industries. Wear plate products are designed for liner applications; they are not intended for use as self-supporting structures or lifting devices. AR500 is a thru-hardened, abrasion resistant, alloy wear plate.See all results for this questionWearplate E CatalogueA high wear resistant steel Creusabro is quench and tempered wear plate available in 4001-1B (4800) and 500HB (8000) (24800 Lined Clamshell ceooo Screw Flight [email protected] 4800(P) C4800 Dust cyclone for Tornago Aluminium [email protected] 4800(P) is a high wear resistant steel, offering a 50% extra in service life compared
Wear Resistant Steel | Wear and Impact Steel |Toronto wear resistant steel plate wear plate with hardness 360hb-55
To reduce wear and abrasion, the 1st requirement is surface hardness and the 2nd is resistance to shearing, tearing or cracking of the steel. The ideal Abrasion Resistant steel (AR) should have 2 characteristics: High initial hardness and the ability to work-harden, complete through hardness, a fine micro structure, good in hot and cold wear resistant steel plate wear plate with hardness 360hb-55Wear Resistant Steel Plates | Hardox 400, 450, 500, 600Wear resistant steel is used in areas where there is likely to be a high degree of abrasion or wear of the steel plate. The key quality for wear resistant steels is their hardness. We are a leading supplier of Hardox 400 / Hardox 450/ Hardox 500 plates in thickness ranging from 4mm to 100mm.Wear Resistant Steel Plates - Wear Resistant Steel wear resistant steel plate wear plate with hardness 360hb-55Wear Resistant Steel Plates Offering you a complete choice of products which include wear resistant steel - hardox 400, abrex 400 plates, wear resistant steel - hardox 600, wear resistant steel, abrex 400 and tiscral tata make 200bhn hardness wear liner plate sail hard.
One of the hardest types of stainless steel after heat treating, 440C offers excellent wear and abrasion resistance. It's often used for bearings, valves, and knife blades. Wear-Resistant 1095 SpringWear Plate - Trimay Wear PlateT138s overlay is a chromium carbide alloy well suited for tough jobs which demand more protection than what any steel alone can offer. T138 wear plate offers a low friction, impact-resistant surface which protects against abrasion and wear, while maintaining a hardness similar to that of annealed steel.Wear + Impact Resistant Steel For Industrial Applications wear resistant steel plate wear plate with hardness 360hb-55When you choose to partner with Clifton Steel, you can rest assured of our customer-centric commitment. Well tirelessly put to work on your behalf our 40+ year tradition of supplying abrasion resistant, impact resistant and wear resistant steel parts for industrial wear applications just like yours.
Overview. Special Treated Pins are Tricon Wear Solutions alloyed steel pins designed to provide high wear resistance and toughness. Tricon Special Treated Pins are produced from vacuum degassed, Calcium-Silicon injected, Ni-Cr- Mo steel pin stock that has been quenched, tempered and stress relieved to 360 BHN minimum.Tool Steel | Good Metals CompanyAir-hardening steel. Replaces O-1 when safer hardening, better dimensional stability and increased wear-resistance are required. Most widely used in the A series. D-2: High carbon and high chrome. Ideal grade for maximum production runs. Superior machinability. Excellent wear-resistance, high compressive strength, and deep hardening properties.The world's widest range of wear-resistant steels - SSABWear-resistant steel is tougher and harder than conventional steel plate and can last up to 4 times longer than conventional high-strength steel. SSABs popular grades of Hardox® AR steel include AR400, AR450, AR500, AR550 and AR600. The numbers refer to their hardness level as measured on the Brinell hardness scale.
Steel - Steel - Wear-resistant steels: Another group is the wear-resistant steels, made into wear plates for rock-processing machinery, crushers, and power shovels. These are austenitic steels that contain about 1.2 percent carbon and 12 percent manganese. The latter element is a strong austenizer; that is, it keeps steel austenitic at room temperature.Specialty Steel Co. | AR400 & AR500 Wear Plate & Bar wear resistant steel plate wear plate with hardness 360hb-55Typical Properties of AR400. AR400 is thru-hardened, abrasion resistant, alloy wear plate. Hardness range is 360/440 BHN with a nominal hardness of 400 BHN. Service Temperature is 400°F. This plate product is intended for use in applications where a good balance of formability, weldability, toughness and abrasion resistance are required.REVIEW OF THE WEAR AND GALLING CHARACTERISTICS HardnessIn general, resistance to wear is increased by increasing hardness, provided other factors remain constant. There is some question, however, whether the controlling hardness is the bulk hardness or simply surface hardness. It has been stated that to increase wear resistance, hardness should be increased by alloying or heat treatment.
QT-PLUS® wear steel plates come in a variety of standard or cut-to-size dimensions. JADCO stocks plate in sizes from 1/4 up to 5 thick. Regardless of whether your QT-PLUS® wear steel application requires drilling, welding, flame cutting or bending, QT-PLUS® will yield outstanding results when these instructions are followed.NM450,NM 450 STEEL PLATE__Steel SupplierWear Resistance Steel Plate NM450,NM 450 STEEL PLATE . NM450 is an abrasion resistant plate with a hardness of 450 HBW, intended for applications where demands are imposed on abrasion resistance in combination with good cold bending properties. NM450 offers very good weldability.NM 600|NM 600 STEEL PLATE__Steel SupplierWear Resistance Steel Plate NM 600|NM 600 STEEL PLATE . NM 600 is an abrasion resistant plate with a hardness of 600 HBW, intended for applications where demands are imposed on abrasion resistance in combination with good cold bending properties. NM 600 offers very good weldability.
SLS600 Wearpipe is achieved by a unique heating/quenching process that alters the steels microstructure through the pipe wall. The result is a pipe with an inner surface hardness of 600 BHN typ. to provide exceptional abrasion resistance while the outer surface, cooling slower, remains more ductile, with a hardness of 250 BHN.Hardness vs. Wear - Superior ConsumablesSubmerged Arc Welding call us today 1-800-567-1362 Hardness vs. Wear By Robert F. Miller Hardness is quite often used in the field of wear resistance as the criteria for judging alloys, castings, hardfacings and overlays. The premise is that the harder the material, the greater the wear resistance. While this is technically correct, applying this Hardness vs. Wear Read More »ENDURA Steel | Toronto, Mississauga ON | Titus SteelBest Wear Resistance of any abrasion resistant plate. 8 times greater wear than mild steel. 2-4 times greater life than conventional 500 BHN steels. Reduce plate thickness up to 25% vs AR 500 (ie. 2 -> 1.5) Ability to Work Harden from 470 BHN to 560 BHN. Ease of
The worlds most wear-resistant fused alloy steel plate Arcoplate is a wear-resistant fused alloy steel plate manufactured by Alloy Steel International. It is a smooth, chromium carbide rich overlay plate manufactured by a patented production process maximising abrasion resistance and reducing hang up.Abrasion Resistant Steel | Wear Resistant Steel Plate wear resistant steel plate wear plate with hardness 360hb-55MAS450 AR Abrasion Resistant Steel (450 Brinell) Used throughout the mining and earthmoving industry, MAS450 AR is Masteels designation for abrasion resistant steel with 450 brinell hardness. The steel is a martensitic hardenable material with excellent high strength and hardness properties making it an ideal choice for heavy wear environments.Some results are removed in response to a notice of local law requirement. For more information, please see here.Abrasion Resistant (AR) & Wear Resistant Steel Plate wear resistant steel plate wear plate with hardness 360hb-55Abrasion resistant (AR) steel plate is a high-carbon alloy steel designed specifically to have greater hardness properties than low-carbon steel. Hardness typically comes at the expense of strength, making AR wear-resistant steel an ideal material for harsh, high-abrasion conditions, and not for structural applications.
AR450 steel plate can reduce industrial wear application issues that may arise due to rubbing or scraping and erosion. By reducing wear, it can maximize your production time and minimize any downtime you previously suffered due to worn parts; This may also improve the longevity of AR400 & AR500 Steel Plate - AR500 Armor | Clifton SteelClifton Steel is a premier supplier of AR400, AR500, A514, Manganese Steel, Armor Plate & More! We solve your wear related problems by providing innovative solutions to the abrasion resistant steel, impact resistant steel and wear resistant steel markets. Learn MoreAR360 and AR400 - available in Hex, Plate, Rectangle wear resistant steel plate wear plate with hardness 360hb-55Alloy & Abrasion Resistant Steel Plate: AR360 / AR400. AR400 and AR360 are quenched & tempered through hardened wear resistant grades of abrasion resistant steel plate used for high impact and abrasion. Both AR360 and AR400 have a minimum brinell of 360. CF Metals premium grade of these products are 360 and 400.
Abrasion resistant steel plates, also known as wear resistant steel plates, are widely used in areas wear the wear and tear of plates is high, such as mining equipment, truck tippers, and cement industry. Available Forms. PlateA-2, D-2, 0 Die, S-7 - Alloy Tool Steel Inc.If greater wear resistance is required other materials may be considered such as air hardening A-2 or 0-2. 0-1 has a machinability rating of 65% to 75% of a 1% carbon tool steel. 0-1 is sold in the annealed condition. Typical annealed hardness is BHN 187/221 Rc 10/18. 0-1 maximum working hardness is BHN 722 Rc 64. 0-1 is capable of meeting ASTM wear resistant steel plate wear plate with hardness 360hb-55


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Nina Shares Her Second Food Festival Dish
The chef presents a dish you didn't see on-air.
Jess: If You Can't Stand the Heat...
... take a break in the drink tent!
Waylynn: "My Work Speaks for Itself"
Waylynn expresses disappointment with Kat's fonuts feature.
Kat explains what happened with Waylynn's "One Year In" interview.
Brenda: About Those "Bloggers"...
Brenda clarifies her comment about food bloggers.


Take home point
The use of social media tools – Facebook, Twitter, LinkedIn, and ResearchBlogging.org – for the purpose of releasing an article in the clinical pain sciences increases the number of people who view the article and download it. Social media tools also have implications for the dissemination of medical research articles in other fields.
Generally, anyone interested in accessing research articles either utilizes a research database such as Pubmed or simply follows a few specific journals. As a result, many articles go unnoticed because end users who could benefit from them lack the time to find them. In addition, those who have time to search these databases may be overwhelmed with lots of articles that are not relevant to their needs.
Social media, on the other hand, does not depend on individuals accessing a database. Instead, end users have information sent to them often by individuals they have elected to follow based on shared interests or personal relationships. Researchers in Australia sought to determine if this unique aspect of social media could be used to increase the dissemination of research. Although this may seem obvious, little evidence exists to support this and researchers sought to contribute to an evidence base in this area.
Approach to Address Problem
The researchers selected 16 PLOS ONE articles using four inclusion criteria relevant to the clinical pain sciences, first published online between 2006 and 2011, of interest to readers of a research group blog (bodyinmind.org), and not previously mentioned in a blog post on bodyinmind.org. The articles were assigned randomly to four researchers who wrote blog posts on them, comprised of approximately 500 words and a link to the online version of the article. These blog posts were randomly assigned two dates: one date for a social media release and one date as a control. The control is not well explained by the researchers and appears to represent a period where nothing is being done to promote the article.
A better comparison would be the initial release of the article online because readers may be more prone to download articles in the latest issue instead of going to the archives to identify articles. In other words, the control may not be an adequate reflection of the amount of attention articles receive without social media releases.
On the social media release data, the researchers sent out their blog posts to researchblogging.org, Facebook, Twitter, and LinkedIn. Posts were released early in the morning (6 – 7 AM) or late at night (11 PM – 2 AM) Australian Eastern Summer Time. They do not clearly indicate the name of the Facebook, Twitter, and LinkedIn accounts that are used or how many people are linked to these accounts (such as number of Facebook friends). Also, given Twitter’s word limitations they are not clear about how they modified the 5oo word post for Twitter.
In addition, the researchers do not indicate whether the people receiving the articles are people who normally receive this type of information from them–perhaps through their bodyinmind.org blog. If so, these individuals may be more likely to uptake this information than others who do not regularly utilize social media tools for getting research information.
The researchers compared response to articles during the control and social media release dates. Their primary outcome variables were HTML views and PDF downloads a week before and after the social media release. They also looked at factors associated with these variables including reach (number of people receiving the blog posts), engagement (likes and other comments on blog posts), and virality (number of people who generated a secondary story from their blog posts–like this one on their research article). They assessed whether these factors led to more HTML views or PDF downloads. They also assessed whether the blog writer had some effect on its success.
The key innovation in this research project was the use of social media to push research information to end users instead of waiting on the end users to “pull” the information from a database.
The key result was a statistically significant increase in HTML views and PDF downloads one week after the blog posts when comparing the control date and the social media release date (p < .05). However, none of the measures of social media reach, engagement, or virality related to the outcome variable. Hence, some other unknown factors are affecting HTML views and PDF downloads.
Implications for clinicians/health care system
Better dissemination of research can save clinicians time by improving the efficiency of information uptake by them. This is useful for health care systems because this is one of the many ways that a health system can improve its quality. One of the challenges is making sure that the information coming from social media is well catered to the needs of clinicians.
Implications for public health
Improved dissemination of research could also provide benefits to the public. In the case of patients or lay individuals, social media can be used to send not only research articles, but lay translations of the information in order to increase the probability of more people understanding the information. This can contribute to increasing health literacy of individuals.
Future research concerns/challenges
Moving forward, researchers in this field could seek to determine which types of health professionals are most likely to utilize social media for the purposes of receiving research information. In addition, they could determine which groups of patients are likely to utilize research information disseminated in this manner. Also, as stated, more clarity in the methods for these studies will help guide subsequent research and improve the ability of future researchers to replicate the findings of work in this area or refute the findings.


Method 1: Search for Specifications Online. Identify the motherboard make and model. Press on the Windows key on your keyboard and start typing System, choose System Information. The motherboard make and model will show under BaseBoard Manufacturer and BaseBoard Product. Enter the motherboard make and model number (identified in step 1) into ... Ryan Perian. Peripheral Component Interconnect is a common connection interface for attaching computer peripherals to the motherboard. PCI was popular between 1995 and 2005 and was most often used to connect sound cards, network cards, and video cards . PCI is also an abbreviation for other unrelated technical terms, like protocol capability ... A PCIe or PCI express slot is the point of connection between your PC’s “peripheral components” and the motherboard. The term “PCIe card” and “expansion card” simply refers to hardware, like graphics cards, CPUs, solid-state drives (SSDs), or HDDs, you may add to your device through PCIe slots, making both catch-all terms for a ... PCI Express 3.0 x16: 1 x PCI Express x16 slot, running at x16 (PCIEX16) * For optimum performance, if only one PCI Express graphics card is to be installed, be sure to install it in the PCIEX16 slot. 1 x PCI Express x16 slot, running at x4 (PCIEX4) * The PCIEX4 slot shares bandwidth with the PCIEX1_2, PCIEX1_3, and PCIEX1_4 slots. When the ... Untuk mengetahuinya lebih jauh, berikut ulasannya Jenis-Jenis Slot PCI. 1. Slot PCI-E X16. Jenis-Jenis Slot PCI yang pertama adalah slot PCI-E X16. Jenis slot PCI ini sudah digunakan sejak motherboard memakai processor tipe LGA 775. Umumnya Processor tipe LGA 775 ini digunakan pada CPU pentium 5 dan juga Celeron. PCIe slots are expansion slots on your motherboard. They’re used to connect more hardware parts to your motherboard to expand its functionality. PCIe slots come in different sizes like PCIe x1, PCIe x4, PCIe x8, PCIe x16, and PCIe x32. Major uses for PCIe slots include connecting GPUs, sound cards, SSD drives, Wifi cards, and so on. A semi-inserted PCI-X card in a 32-bit PCI slot, illustrating the need for the rightmost notch and the extra room on the motherboard to remain backward compatible 64-bit SCSI card working in a 32-bit PCI slot. Most 32-bit PCI cards will function properly in 64-bit PCI-X slots, but the bus clock rate will be limited to the clock frequency of the ... Solution. #2. bamim2 said: Does anyone out there know anywhere or anyone who manufactures or sells new motherboards that have PCI slots (2 or more would be best, but even 1 PCI slot would be OK), a modern BIOS/UEFI, a modern CPU socket type ( either Intel or AMD chipsets) has at least 4 RAM slots with addressing for at least 64GB of RAM, USB ... Fungsi Slot PCI. Slot Peripheral Component Interconnect (PCI) merupakan suatu alat penghubung untuk bus komputer 32-bit. Alat-alat ini terintegrasi pada motherboard komputer dan dapat digunakan untuk memungkinkan penambahan perangkat PCI seperti modem, perangkat keras jaringan, atau kartu suara dan kartu grafis. Pada komputer lama, pengguna ... Different Types of Slots on Motherboard 1. PCI Slots. A PCI slot is an interface on the motherboard that allows you to put in a device that requires power,... 2. PCIe Slots. Image of PCIe or PCI Express slots on the motherboard. PCIe or PCI Express slots are the most common... 3. PCI-X Slots. As a ... The types of PCIe slots available in your PC will depend on the motherboard you buy. PCIe slots come in different physical configurations: x1, x4, x8, x16, x32. The number after the x... The more PCIe lanes a slot has, the higher its throughput rate (speed) and the more demanding expansion cards it can support. You can find four types of PCIe lane configurations on PCIe slots, i.e., x1, x4, x8, and x16. The number after “x” usually tells you the slot’s number of PCIe lanes.


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I’m starting a new segment called Layered to show a glimpse of my post processing work. This is the type of knowledge I wish I had access to when I was first starting Photoshop. Basically, I’ll show the original photo, the finished photo, and the layers I used on Ps. This is like Brooke Shaden’s videos, but I’m too lazy to make time lapse videos of my actual process. Regardless, I hope this is useful to someone out there!
For my first segment, I’m using Diana’s photo from last week. When I do my shoots, I don’t usually have the final image in my mind.. I care more about the composition and (somewhat decent) lighting. When I put the image on Camera Raw and Photoshop, that’s when I actually come up with the “mood” of the photo. I pretty much just let my mind go nuts and that’s when the final product really materializes in my head.. and in turn, in Ps.
Here’s another set with Charmaine. The really liked how the wallpaper popped when I used a couple of speed lights for flash. The wall had a slight red tint to it, so I decided to go along with it on post process by adding a deep red filter (which also makes her red lipstick pop more too).
Filmont is my friend Mike Fildes’ business. He’s an up and coming entrepreneur and his business is selling one of a kind tables. He teams up with tattoo artists from True Tattoo to create these masterpieces. His website is coming soon, but check out some of the product photography.


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Kevin introduced me to several local drops that were well-worth sampling. After some the atmosphere livened up - quite obviously a popular hidden-away haunt. Worth finding it!
Met up with a local from Bamberg who brought us to this cool place. We visited in the nighttime for drinks and conversation. The window was open to the street letting in cool air and people watching. The upstairs place was chic and had a...More
We have discovered this place just by chance. It's in the second floor in the bar street. It looks very old inside. The staff was very nice. Since we haven't had anything for dinner, we ordered some of their food. Big bowl of vegetable soup,...More

domain: travel


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This Makara Sankranti ensemble marks the arrival of the exciting Bommala Koluvu. Rows of Kondapalli toys are put together in an amusing attempt to narrate stories of ritual. Every year, these colourful Kondapalli toys sit patiently in their wooden postures, waiting to be assembled and celebrated by young and old alike.
Each idol is carved from single piece of wood
Sourced directly from local artisans of Kondapalli
Made from “Tella poniki” Light wood
Height x Width x length : 19 x 17 x 22.5 cm
Specification: Artsytribe Handicrafts Kondapalli Makara Sankranti Theme Village
- Store Name: TrickyDolls
- Vendor: TrickyDolls
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