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Fourth in a series of four biographical films on the Polish composer, Witold Lutosławski. Series Advisor...
Witold Lutosławski: Esa-Pekka Salonen and Steven Stucky in conversation
Series Advisor, Steven Stucky and Philharmonia Orchestra Principal Conductor and Artistic Advisor, Esa-Pekka Salonen both knew the Polish composer, Witold Lutosławski well. In this film, the two composers reminisce about their friend and mentor and discuss his work.
Part of the Philharmonia Orchestra's series Woven Words: "Music begins where words end". Explore the series' digital resources at philharmonia.co.uk/lutoslawski


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The current American diet has changed over time to be high in SFA and low in omega-3 fatty acids (12). This change in eating habits is centered on fast food containing high amounts of saturated fat, which has small amounts of essential omega-3 PUFA compared with food prepared in the home (13). Seafood sources such as fish and fish-oil supplements are the primary contributors of the 2 biologically important dietary omega-3 fatty acids, EPA and DHA (14–16). This low intake of dietary EPA and DHA is thought to be associated with increased inflammatory processes as well as poor fetal development, general cardiovascular health, and risk of the development of Alzheimer's disease (AD).
56. Davidson MH, Stein EA, Bays HE, et al. COMBination of prescription Omega-3 with Simvastatin (COMBOS) Investigators. Efficacy and tolerability of adding prescription omega-3 fatty acids 4 g/d to simvastatin 40 mg/d in hypertriglyceridemic patients: an 8-week, randomized, double-blind, placebo-controlled study. Clin Ther. 2007;29:1354–1367. [PubMed]
ALA is an essential fatty acid, which means that you need it but you must get this fat from your diet because your body is unable to produce it. In general, omega 3 fats are a crucial component of all cell membranes, including the eye (retina) and brain as well as aiding in the process of energy production to support functions involving the heart, lungs, immune system, and hormones (endocrine system), work properly.1
Several studies suggest that people suffering symptoms of depression and/or anxiety see improvement after adding an omega-3 supplement to their routine, even in double-blinded, randomized, controlled trials. (29, 30, 31, 32, 33) At least one study comparing a common depression medication found omega-3 supplements to be just as effective in combating depression symptoms. (34)
In fact, dietary fat intake has been among the most widely studied dietary risk factors for breast and prostate cancers. Two studies from 2002 explain how omega-3 can protect against breast cancer. BRCA1 (breast cancer gene 1) and BRCA2 (breast cancer gene 2) are two tumor suppressor genes that, when functioning normally, help repair DNA damage, a process that also prevents tumor development.
Lok CE, Moist L, Hemmelgarn BR, Tonelli M, Vazquez MA, Dorval M, Oliver M, Donnelly S, Allon M, Stanley K; Fish Oil Inhibition of Stenosis in Hemodialysis Grafts (FISH) Study Group. Effect of fish oil supplementation on graft patency and cardiovascular events among patients with new synthetic arteriovenous hemodialysis grafts: a randomized controlled trial. JAMA 2012;307(17):1809-16. View abstract.
For several years now, the fish oil and Alzheimer’s disease connection has been studied with consistent results. The essential fatty acids vital for brain function that are found in fish oil can not only slow cognitive decline, but can help prevent brain atrophy in older adults. A study published in the FASEB Journal looked at the health effects of four- to 17-month dietary supplementation with omega-3 fatty acids and antioxidants. The findings once again confirm the potential for fish oil to be used as a weapon to fend off the onset of cognitive decline and Alzheimer’s disease. (8)
Children: Fish oil is POSSIBLY SAFE when taken by mouth appropriately. Fish oil has been used safely through feeding tubes in infants for up to 9 months. But young children should not eat more than two ounces of fish per week. Fish oil is POSSIBLY UNSAFE when consumed from dietary sources in large amounts. Fatty fish contain toxins such as mercury. Eating contaminated fish frequently can cause brain damage, mental retardation, blindness and seizures in children.
Additional side effects of fish oil supplements which have been reported include headache, short-term memory loss, depression, somatic disorders, and increased risk of colon cancer, nasopharyngitis, worsening of asthma symptoms, hemolytic anemia, decreased physical activity, increased appetite, a general uncomfortable feeling or increased blood pressure. The percentage of users that develop these side effects is not known. If these side effects become severe it is recommended that you stop using fish oil supplements.
ADD ADHD Ageing Allergies Alzheimer's Arthritis Autism baby Behaviour Brain function Cancer CFS Chronic Fatigue Concentration Dementia Depression Diabetes Digestion Dyslexia Dyspraxia Energy EPA Fertility Fibromyalgia General Health Good fats Healthy omega-3 Heart health Hormones IBS Immune System Inflammation Joints M.E. Mental health Mood Omega-3 Pregnancy Psoriasis Skin Sleep Stress Vegetarian nutrients Vegetarian Omega-3 Weight management
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Those foods provide enormous amounts of other nutrients that are good for you. nSo it is way better to eat those foods than to take fish oil. With that said, some people find it very difficult to get vitamin A or vitamin D, and particularly for vitamin A, cod liver oil may be a very important source of that vitamin. Cod liver oil is a form of fish oil that happens to be high in the fat-soluble vitamins. Vitamin A is best found in liver. It’s better in my opinion to eat liver once a week, but there are a lot of people out there who are not going to eat liver once a week. So if you are using cod liver oil to get the vitamins that you can’t get from food—and I should point out that vitamin A can also be derived from plant foods, but many people genetically or for other reasons don’t derive it very well from plant foods.
Could you be deficient in omega-3s? The University of Maryland Medical Center says that the symptoms “include fatigue, poor memory, dry skin, heart problems, mood swings or depression, and poor circulation.” They also warn against a poor omega-3 to omega-6 ratio, cautioning readers that it may be “associated with worsening inflammation over time.” (6)
The studies examining the possible benefits of omega-3s continue. Researchers are looking at a range of health outcomes and the impact of a heart healthy diet rich in omega 3 fatty acids on a range of chronic disease. For instance, Dr. Hooper's team is beginning to evaluate the effects that omega-3 fats may have on diabetes, dementia, and some cancers.
Dioxins and PCBs may be carcinogenic at low levels of exposure over time. These substances are identified and measured in one of two categories, dioxin-like PCBs and total PCBs. While the U.S. FDA has not set a limit for PCBs in supplements, the Global Organization for EPA and DHA (GOED) has established a guideline allowing for no more than 3 picograms of dioxin-like PCBs per gram of fish oil. In 2012, samples from 35 fish oil supplements were tested for PCBs. Trace amounts of PCBs were found in all samples, and two samples exceeded the GOED‘s limit. Although trace amounts of PCBs contribute to overall PCB exposure, Consumerlab.com claims the amounts reported by tests it ordered on fish oil supplements are far below those found in a single typical serving of fish.
The University of East Anglia (UEA) is a UK Top 15 university. Known for its world-leading research and outstanding student experience, it was awarded Gold in the Teaching Excellence Framework and is a leading member of Norwich Research Park, one of Europe’s biggest concentrations of researchers in the fields of environment, health and plant science. www.uea.ac.uk.
CHAMPAIGN, Ill. — Chemical compounds called cannabinoids are found in marijuana and also are produced naturally in the body from omega-3 fatty acids. A well-known cannabinoid in marijuana, tetrahydrocannabinol, is responsible for some of its euphoric effects, but it also has anti-inflammatory benefits. A new study in animal tissue reveals the cascade of chemical reactions that convert omega-3 fatty acids into cannabinoids that have anti-inflammatory benefits – but without the psychotropic high.
Finally, in order for AA to be converted into inflammatory products it must be released from phospholipids (part of the cell membrane) using the enzyme phospholipase A2 and then converted by the enzyme cyclooxygenase. EPA utilises both of these enzymes, so if EPA levels are increased in the diet, it attracts enzyme away from AA to EPA – again giving rise to anti-inflammatory products instead of inflammatory ones.
"Fish is still the mainstay of the diet in many parts of the world where there is very little heart disease," he says. "I think when you replace higher fat foods and highly processed foods with fish there is going to be some benefit.'' So it may be that by substituting fish for red meats, bacon and luncheon meats, and similar high-fat foods, you are making a change that will lead to improving your health outcomes, he says.
One of the most well-known benefits of omega-3s are the way they positively affect risk factors associated with heart disease. That’s one reason the American Heart Association is very clear about encouraging people to get enough in their diets. (8) Heart disease and stroke are the leading causes of death worldwide, but communities who eat diets rich in fish have remarkably low instances of these diseases, which is at least partially due to their high omega-3 consumption. (9, 10)
A 2009 metastudy found that patients taking omega-3 supplements with a higher EPA:DHA ratio experienced fewer depressive symptoms. The studies provided evidence that EPA may be more efficacious than DHA in treating depression. However, this metastudy concluded that due to the identified limitations of the included studies, larger, randomized trials are needed to confirm these findings.
Before getting to know some of the fish oil side effects, you have to know more about fish oil, like its benefits and usages. Fish oil has become a popular supplement for athletes, as well as those looking to improve their overall health. Many claims have been made regarding the improvements to the body which can be made by using fish oil to increase the body's level of fatty omega-3 acids. Some of these claims have been backed up by studies, while others have not been proven with significant scientific evidence. There are also some precautions that need to be addressed if you will be taking fish oil regularly. People with certain health conditions may see a worsening of their symptoms if they increase their intake of fatty acids too quickly or with the wrong products.
According to the Cardiovascular Research Institute in Maastricht in Netherlands, “Epidemiological studies show that replacing fat with carbohydrates may even be worse [than the Western-type high-fat diet] and that various polyunsaturated fatty acids (FA) have beneficial rather than detrimental effects on CVD (cardiovascular disease) outcome.” This includes fish-oil fatty acids with anti-inflammatory properties, which can help prevent and reverse a plethora of cardiovascular diseases. (19)
Omega-3 fats may also impact the development of arthritis. As far back as 1959, studies were published about the effectiveness of cod liver oil on arthritic patients. In the 1959 study, 93 percent of participants “showed major clinical improvement.” (73) While there is no evidence that high omega-3 levels can prevent the development of arthritis, it seems clear that they can reduce inflammation that causes the typical bone and joint pain experienced in the disease. (74)
Like its other leafy green counterparts, broccoli is a powerful source of ALA, one of the omega-3 fatty acids your body needs (but can’t make on its own). Broccoli is also high in fiber, zinc, and — surprisingly — protein, a must for any ADHD brain. If you or your child doesn’t like broccoli, try pairing it with a cheesy sauce or baking it into tots — try this simple recipe to get started.
An analysis based on data from the Norwegian Women and Cancer Study (NOWAC) with regards to the dangers of persistent organic pollutants (POPs) in cod liver came to the conclusion that "in Norwegian women, fish liver consumption was not associated with an increased cancer risk in breast, uterus, or colon. In contrast, a decreased risk for total cancer was found."
Some people who are hypersensitive to fish or have a known allergy to fish products may have a negative reaction to fatty acids which were derived from fish. Some fish oil tablets are also produced with alpha-linolenic acids which come from nuts, which may aggravate those which have an allergy to these products. In many cases these allergies will manifest themselves as a skin rash, but the symptoms could be more severe depending on the severity of your allergies. People with this concern will need to avoid using these products.
36. Marchioli R, Barzi F, Bomba E, Chieffo C, Di Gregorio D, Di Mascio R, Franzosi MG, Geraci E, Levantesi G, Maggioni AP, et al. Early protection against sudden death by n-3 polyunsaturated fatty acids after myocardial infarction: time-course analysis of the results of the Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico (GISSI)-Prevenzione. Circulation. 2002;105:1897–903. [PubMed]
Davidson, M. H., Stein, E. A., Bays, H. E., Maki, K. C., Doyle, R. T., Shalwitz, R. A., Ballantyne, C. M., and Ginsberg, H. N. Efficacy and tolerability of adding prescription omega-3 fatty acids 4 g/d to simvastatin 40 mg/d in hypertriglyceridemic patients: an 8-week, randomized, double-blind, placebo-controlled study. Clin Ther 2007;29(7):1354-1367. View abstract.
Secondly, when we consume EPA, it inhibits the production of AA from DGLA and also competes with AA for uptake into cell membranes and can therefore lower the amount of AA in membranes by literally saturating the cell – in essence, it takes up more of the available ‘space’ and displaces AA. When there is less AA present, there is a reduced capacity for it to produce inflammatory products.
Fish oil is a commonly used dietary supplement, with sales in the U.S. alone reaching $976 million in 2009. Problems of quality have been identified in periodic tests by independent researchers of marketed supplements containing fish oil and other marine oils. These problems include contamination, inaccurate listing of EPA and DHA levels, spoilage and formulation issues.
While fish for dinner is one way to get EPA and DHA, most people don’t eat the suggested two to three servings of oily fish per week to reap the benefits of omega-3s. What’s more, there are extremely few food sources, aside from fish, that naturally provide EPA and DHA. With all the benefits that can come from fish oil, it’s no surprise that these supplements are increasing in popularity.
A 2012 study involved children from 6 to 12 years of age with ADHD who were being treated with methylphenidate and standard behavior therapy for more than six months. The parents of these children reported no improvement in behavior and academic learning using these standard treatments. The researchers randomly gave some of the children an omega-3 and omega-6 acid supplementation or a placebo. They found “statistically significant improvement” for the omega group in the following categories: restlessness, aggressiveness, completing work and academic performance. (5)
Fortier, M., Tremblay-Mercier, J., Plourde, M., Chouinard-Watkins, R., Vandal, M., Pifferi, F., Freemantle, E., and Cunnane, S. C. Higher plasma n-3 fatty acid status in the moderately healthy elderly in southern Quebec: higher fish intake or aging-related change in n-3 fatty acid metabolism? Prostaglandins Leukot.Essent.Fatty Acids 2010;82(4-6):277-280. View abstract.
The bottom line of all that is that there was no clear health benefit from consuming omega-3 fatty acids in food or supplements. There was a suggestion of a possible benefit from LCn3 on cardiac events, but this did not hold up when they took into consideration the quality of the evidence. The better trials, with less risk of bias, tended to be negative.
Eicosatetraenoic Acid (ETA): ETA is a lesser-known omega-3 fatty acid that also contains 20 carbons, like EPA, but only four bonds instead of five. It is found richly inroe oil and green-lipped mussel and is only recently being recognized for its potent health benefits. Not only is it anti-inflammatory, like the other omega-3s, but ETA can also limit your body’s production of the inflammatory omega-6 fatty acid arachidonic acid (ARA). In fact, ETA redirects the enzyme that normally creates ARA to convert it to EPA instead!
Henriksen, C., Haugholt, K., Lindgren, M., Aurvag, A. K., Ronnestad, A., Gronn, M., Solberg, R., Moen, A., Nakstad, B., Berge, R. K., Smith, L., Iversen, P. O., and Drevon, C. A. Improved cognitive development among preterm infants attributable to early supplementation of human milk with docosahexaenoic acid and arachidonic acid. Pediatrics 2008;121(6):1137-1145. View abstract.
It can be challenging to get the appropriate intake of EPA and DHA through diet alone, even though EPA and DHA are produced by water plants such as algae and are prevalent in marine animals. A shorter chain omega-3 fatty acid, α-linolenic acid (ALA),6 is a prominent component of our diet as it is found in many land plants that are commonly eaten, but it does not provide the health benefits seen with EPA and DHA. Although it is possible for the body to convert ALA to EPA and DHA by enlongase and desaturase enzymes, research suggests that only a small amount can be synthesized in the body from this process (8). For example, 1 study suggested that only ∼2 to 10% of ALA is converted to EPA or DHA (9), and other studies found even less: Goyens et al. (10) found an ALA conversion of ∼7% for EPA, but only 0.013% for DHA; Hussein et al. (11) found an ALA conversion of only 0.3% for EPA and <0.01% for DHA.
Higher visual acuity after DHA supplementation is a consistent finding in infants born preterm. For infants born at term, the results are less consistent and are better explained by differences in sensitivity of the visual acuity test (electrophysiologic tests being more sensitive than subjective tests) or by differences in the amount of DHA included in the experimental formula.
Giacco, R., Cuomo, V., Vessby, B., Uusitupa, M., Hermansen, K., Meyer, B. J., Riccardi, G., and Rivellese, A. A. Fish oil, insulin sensitivity, insulin secretion and glucose tolerance in healthy people: is there any effect of fish oil supplementation in relation to the type of background diet and habitual dietary intake of n-6 and n-3 fatty acids? Nutr.Metab Cardiovasc.Dis. 2007;17(8):572-580. View abstract.
Meanwhile, blood levels of DHA and EPA are very transitory, reflecting what an individual consumed only recently, while of course prostate cancer has a markedly longer progression. The study was not designed to isolate omega oil :: prostate cancer relationships, so conclusion would be weak. Seems likely to me that when faced with a serious disease, men suddenly begin to try living “right” in a hurry.
A scientific review published in 2013 looked at omega-3 polyunsaturated fatty acids and prostate cancer prevention. Researchers concluded that there’s a great deal of evidence suggesting that omega-3s have antiproliferative effects – which means they inhibit cancer cell growth – in cancer cell lines, animal models and humans. In addition, the “direct effects on cancer cells” and indirect anti-inflammatory effects on the immune system fighting the cancer likely contribute to the ability of omega-3 fatty acids to inhibit tumor growth. (14)
Fish oil is oil derived from the tissues of oily fish. Fish oils contain the omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), precursors of certain eicosanoids that are known to reduce inflammation in the body, and have other health benefits, such as treating hypertriglyceridemia, although claims of preventing heart attacks or strokes have not been supported. Fish oil and omega-3 fatty acids have been studied in a wide variety of other conditions, such as clinical depression, anxiety, cancer, and macular degeneration, yet benefits in these conditions have not been verified.
Kremer, J. M., Lawrence, D. A., Petrillo, G. F., Litts, L. L., Mullaly, P. M., Rynes, R. I., Stocker, R. P., Parhami, N., Greenstein, N. S., Fuchs, B. R., and . Effects of high-dose fish oil on rheumatoid arthritis after stopping nonsteroidal antiinflammatory drugs. Clinical and immune correlates. Arthritis Rheum. 1995;38(8):1107-1114. View abstract.
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Both omega−6 and omega−3 fatty acids are essential: humans must consume them in their diet. Omega−6 and omega−3 eighteen-carbon polyunsaturated fatty acids compete for the same metabolic enzymes, thus the omega−6:omega−3 ratio of ingested fatty acids has significant influence on the ratio and rate of production of eicosanoids, a group of hormones intimately involved in the body's inflammatory and homeostatic processes, which include the prostaglandins, leukotrienes, and thromboxanes, among others. Altering this ratio can change the body's metabolic and inflammatory state. In general, grass-fed animals accumulate more omega−3 than do grain-fed animals, which accumulate relatively more omega−6. Metabolites of omega−6 are more inflammatory (esp. arachidonic acid) than those of omega−3. This necessitates that omega−6 and omega−3 be consumed in a balanced proportion; healthy ratios of omega−6:omega−3, according to some authors, range from 1:1 to 1:4. Other authors believe that a ratio of 4:1 (4 times as much omega−6 as omega−3) is already healthy. Studies suggest the evolutionary human diet, rich in game animals, seafood, and other sources of omega−3, may have provided such a ratio.
When taking fish oil, more is not always better. Remember that you want it to stay in a balanced ratio with omega-6 fats. For most people, I recommend a 1,000-milligram dose of fish oil daily as a good amount and the most scientifically studied dosage. I highly recommend not taking more than that unless directed to under the supervision of a doctor.
I've done a lot of research on fish oil and Body Vega meets all of the important criteria. They have recommended levels of EPA and DHA and it is molecularly distilled, pharmaceutical grade. The price is reasonable and there are no fishy burps. I tried another brand in the past that met the criteria, but got tired of the fishy burps. I switched to Body Vega a few months ago and have been pleased. So yes, you can find an excellent fish oil without tasting it 30 minutes later. Another good thing about this fish oil compared to one I've tried in the past is that you only need 2 daily capsules compared to 3 with the other brand I tried.
Jump up ^ Abdelhamid, Asmaa S; Brown, Tracey J; Brainard, Julii S; Biswas, Priti; Thorpe, Gabrielle C; Moore, Helen J; Deane, Katherine HO; AlAbdulghafoor, Fai K; Summerbell, Carolyn D; Worthington, Helen V; Song, Fujian; Hooper, Lee (18 July 2018). "Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease". Cochrane Database of Systematic Reviews. doi:10.1002/14651858.CD003177.pub3.
The Department of Ecology of the State of Washington has ranked various seafood based on its EPA and DHA concentrations. The highest-ranking seafood is mackerel, excluding King mackerel, that has a concentration of 1,790 milligrams of combined EPA and DHA per 100 grams, followed by salmon at 1,590; bluefin tuna has between 1173 and 1504 milligrams; sardines contain 980 milligrams; albacore tuna has 862 milligrams; bass has 640 milligrams; tuna has 630 milligrams; trout and swordfish have 580 milligrams; and walleye has 530 milligrams. Other seafood, which includes sea bass, clams, lobster, scallops, catfish, cod, pollock, crayfish and scallops contains between 200 and 500 milligrams of EPA and DHA per 100 grams. Breaded fish products rank lowest on the list with only 0.26 milligram per 100 grams.
It exists in nature in three forms, one derived from land plants and two derived from marine sources. In the body, omega-3 is highly concentrated in the brain; it is critical to the formation and maintenance of nerve cell membranes. Research shows that in the nervous system, omega-3s foster the development of brain circuitry and the processing of information. They also play important roles in stabilizing mood and staving off cognitive decline. Low levels of omega-3s are linked to poor memory and depression. Omega-3 fats are also critical for the formation of anti-inflammatory molecules in the body.
Here is a brief on omega-3 fatty acids: There are three types of omega-3 fatty acids, namely alpha-linolenic acid (ALA), docosahexaenoic acid (DHA), and eicosapentaenoic acid (EPA). All three are important for the body. Vegetable sources, including flaxseed oil, soybean oil, hemp oil, canola oil, walnut oil, rapeseed, perilla, chia, and tofu are rich in ALA. The human body has the ability to convert ALA to DHA and EPA, though there are certain limitations to this conversion.
Back in 2013, a study came out that made a lot of people concerned about fish oil supplements and cancer. The study, published in the Journal of the National Cancer Institute, showed that men who consume the largest amount of fish oil had a 71 percent higher risk of high-grade prostate cancer and a 43 percent increase in all types of prostate cancer. The study was conducted on 2,227 men, of which 38 percent of the men already had prostate cancer. (39)
Three omega−3 fatty acids are important in human physiology, α-linolenic acid (18:3, n-3; ALA), eicosapentaenoic acid (20:5, n-3; EPA), and docosahexaenoic acid (22:6, n-3; DHA). These three polyunsaturates have either 3, 5, or 6 double bonds in a carbon chain of 18, 20, or 22 carbon atoms, respectively. As with most naturally-produced fatty acids, all double bonds are in the cis-configuration, in other words, the two hydrogen atoms are on the same side of the double bond; and the double bonds are interrupted by methylene bridges (-CH
Whilst EPA and DHA are both considered to be important regulators of immunity, platelet aggregation and inflammation, their health-influencing by-products arise from very different pathways and their effects in the body differ. DHA is the most abundant omega-3 fatty acid in cell membranes, present in all organs and most abundant in the brain and retina, playing an important structural role. EPA is present structurally only in minute quantities, always being utilised and under constant demand to be replaced. Whilst DHA provides mainly a structural role, it is becoming evident that EPA may be the dominant functional fatty acid out of the two in many areas of health and especially in inflammatory conditions.
Oe, H., Hozumi, T., Murata, E., Matsuura, H., Negishi, K., Matsumura, Y., Iwata, S., Ogawa, K., Sugioka, K., Takemoto, Y., Shimada, K., Yoshiyama, M., Ishikura, Y., Kiso, Y., and Yoshikawa, J. Arachidonic acid and docosahexaenoic acid supplementation increases coronary flow velocity reserve in Japanese elderly individuals. Heart 2008;94(3):316-321. View abstract.

domain: medical


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Gary smalley five love languages
The 5 Love Languages: The Secret to Love that Lasts by Gary Chapmanthis book is a tool through which the author, gary chapman, can play out his jesus-complex disguised as a relationship self-help book. there are references from the bible throughout almost every chapter and gary likes to include generous praise from his clients who call him a miracle worker. its damn-near pretty close to being called god.
the book has all the hallmarks of a bestseller: easy to read (i read it in one day); hopeless circumstances that seem beyond repair; and an uplifiting ending. the more bestsellers i read, the more i realize that the formula for mainstream media isnt just used in music and movies, its used in books, too. ugh, how annoying. i admit, i was almost sold on it, too. the author used just the right amount of despair and at the appropriate moments, instilled hope for a better future. and while hope isnt bad at all, the book lacks in addressing the complexity of relationships as well as the diversity of relationships in todays world. for example, this book may not translate well in multicultural relationships that are dictated by a whole different set of mores and values. also, i wonder how it would be relevant to queer couples or polyamourous relationships. its quite apparent that this book is meant for hetero-white-christian-monogamous couples.
but the one major caveat of this book that isnt so much a caveat as a poorly disguised advocate of misogyny, is the case of a woman who has been abused (what type of abuse has been perpetrated isnt made explicit and garys reluctance to do so makes me suspicious of how the church deals with issues of domestic violence). garys advice? dismiss any of your own feelings of discomfort (being used for sex) and have sex with your husband as an act of love and hope that he will reciprocate that love. and what i dont understand is how people have overlooked this, even people who are in the psychology field. thats one thing he doesnt really address, how to identify your limits and make compromises. if you cant see the problem with this picture, i pray you never get married. or have a relationship. or speak to people.
the gender roles in this book are fucking archaic. theres this little section where gary talks about the gender differences in sexual desire. according to him, these differences are all physiologically based. men simply have more tension built-up as a result of massive sperm generation whereas women dont, and that is why women dont crave sex the way men do. instead, women only want sex if their men meet their emotional needs. what, do men not need to have their emotional needs met? are they really just fucking animals who want to empty their over-spermed dicks? why dont they just jack off into a toilet for crying out loud? oops, am i not supposed to mention masturbation in the presence of god? and gary makes women seem like fucking prudes from the latest harlequin romance, the christian edition. gag. this man has very little knowledge of couples outside the realm of christian folklore.
his section on physical touch made me laugh. i wasnt sure if the lame attempts at humor were to assuage his own discomfort or that of his audience. yes, gary, people have sex. i understand that when you tell me to rub my partners leg with my foot that i should make sure im not rubbing the dog. harhar.
to be fair, he touched on the basic fundamentals of communication with your partner, but i can hardly call this book revolutionary. his book on the five languages of love for children sound more useful just because the developmental stage they are in matches the dumbed-down tone of the book. youd think he was writing for couples who were born in a vaccuum.
im so over reading new york times bestsellers. weve been brainwashed into accepting that the typical mainstream formula is quality literature. i prefer real talk to fluffy shit, thank you.
The Five Love Languages Gary Chapman Audiobook
❤ Five Love Languages Quiz: Which One Do You Speak?
Gary Chapman reveals that each of us primarily speaks with one of five love languages: quality time, physical touch, gift giving, acts of service, and words of affirmation. People tend to give love the way they naturally prefer to receive love. Knowing your love language, you can better express your needs to your partner while also understanding how to make them feel loved in return. This not only helps in romantic relationships, but also improves the way we interact with anyone, whether in the office, with our family, or when meeting new friends. By understanding we give and receive love, we can show people we care and make them feel loved and appreciated. You can observe how others express themselves to figure out their love language Science Technology Education.
Do you know the 5 Love Languages? Out of these five, each of you has a primary love language which speaks Written by Gary Chapman.
full body burden chapter 4 summary
About Dr. Gary Chapman:
Social Butterfly or Hermit Crab? Do you flock to the crowds, or do you prefer to sit at home on a Friday night, reading a good book? Has it been months since sunlight touched your skin, or are you always out and about, having a good time?
Gary Chapman presents a simple truth: relationships grow better when we understand each other. Everyone gives and receives love differently, but with a little insight into these differences, we can be confidently equipped to communicate love well. This is true for all forms of relationship — for married or dating couples, for children and teenagers, for friends and coworkers, for long-distance relationships, for those brand-new loves and for the romances that are older than the hills. In his early years as a marriage counselor, Dr. Gary Chapman noticed over and over that couples would voice similar complaints regarding their marriage.
The phrase has been ubiquitous since Dr. The other four are just as important and offer [other] ways to express love to each other. Tina B. This language, says Chapman, is all about giving your partner your undivided attention. That means no TV, no chores, no cell phone — just giving each other your undivided attention.

domain: literature


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12 Tested Positive For COVID19 In Odisha’s Puri Before Bahuda Yatra
Puri: Twelve persons have been tested Covid-19 positive during the Phase-2 testing for Bahuda Yatra in Puri town.
A total 5569 Covid-19 swab samples were collected last week from Puri town. Out of which 12 have tested positive for the deadly Coronavirus. All the confirm cases have been shifted to the Covid hospitals. Contact tracing and containment area have been successfully adhered to.
As per Hon’ble Supreme Court instructions, only persons who have been tested negative for Covid-19 will be allowed in Bahuda Yatra.
The total number of positive cases in Puri is 256, out of which 44 are active cases, while 210 are recovered cases and one have succumbed to this virus.

domain: news


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Here's a sample of our volunteer opportunities:VIEW AS
Newborns in Need strives to be a positive presence in the local community by helping parents with a newborn provide their little one with essential care products.
Newborns in Need is a 501 © 3 nonprofit charity that donates essential baby items to hospitals, homeless shelters, family crisis centers, and other organizations that provide for the needs of newborn babies that are sick or in crisis. Many of the babies we help are born into families living in poverty and do not have adequate clothing, blankets, or essential care products. Our Northern WV Chapter of Newborns in Need is made up of volunteers who distribute handmade and donated items to these newborns. We also perform fundraisers to be able to purchase baby essentials when a need arises.
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Request administrator status and update its information!

domain: sociology


text:
"Complement C1r" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 80-kDa subcomponent of complement C1, existing as a SERINE PROTEASE proenzyme in the intact complement C1 complex. When COMPLEMENT C1Q is bound to antibodies, the changed tertiary structure causes autolytic activation of complement C1r which is cleaved into two chains, A (heavy) and B (light, the serine protease), connected by disulfide bonds. The activated C1r serine protease, in turn, activates COMPLEMENT C1S proenzyme by cleaving the Arg426-Ile427 bond. No fragment is released when either C1r or C1s is cleaved.
This graph shows the total number of publications written about "Complement C1r" by people in Harvard Catalyst Profiles by year, and whether "Complement C1r" was a major or minor topic of these publication.
To see the data from this visualization as text, click here.


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1. Birth dose of OPV is a must.
2. Ideally IPV should replace OPV as early as possible.
3. Minimum age of administration of IPV is 6 weeks with the best option being 3 doses of IM IPV in 6-10-14 weeks schedule.
4. bOPV should be continued in place of IPV, only if IPV is not feasible, with a minimum of 3 doses at 6,10,14 weeks of age.
Extra doses of Oral Polio(pulse Polio) on all Supplementary immunization activities should continue, irrespective of primary vaccination with OPV or IPV.
Read more related information, Click Here
If you have a question on some other topic, Click Here


Around two thousand years ago, a girl called Mary gave birth to a baby. According to the story, she knew He was special. Joseph did, too. But nobody else did, not until after. (Even the shepherds showed up post-birth.)
I’ve heard and read several things this season that have changed my visual image of the story. Internally, I always pictured things a lot like a Nativity scene—quiet barn, peaceful animals, Joseph, Mary, baby. Peaceful isolation. But of course, that’s not a reflection of the culture of the time. There would have been midwives, extended family, neighbors. If nothing else, given the crowds we’re told had descended on Bethlehem, there would have been strangers in tents nearby. And birth isn’t generally quiet, so this must have been a community affair. Mary likely had too little privacy, not too much.
In whatever crowd had gathered—and I’m not a Biblical scholar, so this is me wondering, not stating anything as fact—most folks probably thought this was a perfectly normal baby. There might have been a little judgey-ness, given that Mary and Joseph weren’t married. And older women offering advice on breastfeeding. Toddler cousins running around underfoot (after all, this was Joseph’s place of ancestry, right?) Men indulging in some equivalent of cigars, since Jesus was a first-born son.
But I think it’s unlikely that anyone, except for those who had personally seen the angels, would have thought that Jesus would still be talked about today. A miracle, yes, but no more so than any other baby. How many were born in Bethlehem that week?
Now, we anticipate the His birth so much that many Christians devote a whole month to it. Advent lasts twenty-four days, which is nearly 7% of the year—every year.
So if the people gathered around Mary had no idea what they were witnessing, it makes me wonder: do we?
Would we notice if something happened in our barn that people would still be talking about in a couple of thousand years? We’ve got a twenty-four hour news cycle and a whole Internet brimming with cat videos. We know so much more about what’s happening than our ancestors did, so much more than they even could have imagined, at least if you’re tracking by breadth and not depth. Does that mean we recognize the birth of true miracles? The Herald of the New and Holy? It might be a sound that’s commonplace. Back then, it was a baby’s cry.
While we can celebrate God’s miracles every day, and many of us do, the holiest, most world-altering event of my life, or yours, or anyone else’s might be something we never recognize. We might have no idea that this is the thing creation will celebrate in two thousand years. And we might even take an active role in it. We might midwife the miracle. We might smile at a stranger, or stop a child from stepping into the street, or even say a prayer at just the right time, and somehow that results in the thing that brings joy to the world and all of its people.
You might have done it yesterday.
You might do it tomorrow.
And in that way, every day is Christmas Eve.


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Maine is expected to have nearly $130 million in surplus revenues during the two-year budget cycle that ends in 2019, according to the latest projects from the state’s Revenue Forecasting Committee.
That’s great news (but not entirely unexpected because the state regularly ends its fiscal years with additional money on hand). The money can go toward fulfilling a state law requiring the expansion of Medicaid, which was approved by voters last year.
Gov. Paul LePage, who vetoed expansion legislation five times, has laid out a set of standards for funding the expansion, which he said, during his State of the State address, he would “enforce” as state law.
The funding standards include not raising taxes, not cutting funds for nursing homes or people with disabilities, not taking money from the Rainy Day fund and not using gimmicks. The surplus funds identified by the Revenue Forecasting Committee meet these criteria.
According to the nonpartisan Maine Office of Fiscal and Program Review, it would cost the state $55 million to pay for the expansion in fiscal year 2021, the first year of full implementation. That year, Maine will receive $525 million from the federal government, which covers 90 percent of the cost of expansion. The $55 million figure represents 1.5 percent of a single year of state spending.
Simple math shows the benefits to Maine far outweigh the costs by nearly 10-to-1. Even without the revenue surplus, Maine can afford to expand Medicaid. The surplus simply makes it easier.
By expanding Medicaid, Maine will make insurance coverage available to 80,000 Mainers. These are people who work but can’t afford health insurance or their employer doesn’t offer it. They are not poor enough or do not have a disability to qualify for Medicaid without an expansion.
Extending health insurance coverage to these Mainers will allow them to access preventative care, vaccinations, addiction treatment, counseling and other needed care. Currently, many people without insurance put off doctor’s visits until illnesses or injuries become so bad they threaten their work and wellbeing. When they do seek care, it is more expensive. The cost of that expensive care is borne by hospitals and those with insurance as rates are raised to cover the cost of caring for the uninsured. In fact, a recent analysis found that private insurance premiums were about 7 percent lower in states that had expanded Medicaid compared to those that had not.
Medicaid expansion will also put Maine hospitals on more secure financial footing by reducing their uncompensated care and expanding their patient base. In many rural communities, hospitals are the largest employers.
Thirty-three states, many of them led by Republican governors, have expanded Medicaid. No state has undone its expansion, negating the false arguments that expansion busts state budgets, leads to tax increases and reduced care for the elderly.
There are many ways Maine can pay for Medicaid expansion, including within existing revenues without tapping the surplus. But, the predicted surplus should make the discussion around how to pay for extending health insurance to thousands of low-income Mainers much simpler.
Follow BDN Editorial & Opinion on Facebook for the latest opinions on the issues of the day in Maine.

domain: finance


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Empirical Orthogonal Function (EOF) analysis for various climate variables (2m air temperature, precipitation, 500 hPa
geopotential height) from the transient 21,000-year-long paleoclimate simulation 'sim2bl' of Timm and Timmermann (2007).
Explained variances, loading pattern (in units of the variables) and the normalized principal component time series are shown.
Four different regions (global, Northern Hemisphere, Southern Hemisphere, tropical latitude belt) were analyzed in three different time ranges (21,000BP -
preindustrial time, deglaciation 21,000-10,000 BP, Holocene 10,000BP - preindustrial time).
Select the EOF analysis plot you wish to view and press the "Plot it!" button.
Sim2bl EOF analysis
Note: Information for time axis of the normalized PC (principal component time series): years [1000 BP]

domain: geography


Abstract: how to improve the measuring accuracy of electromagnetic flow meter
scale by variable diameter information produced by excellent flow meter, flow meter manufacturer to offer you the quotation.
How to improve the measurement precision of the electromagnetic flowmeter
by variable diameter we all know that electromagnetic flowmeter measurement principle is Faraday's law of electromagnetic induction, it is mainly used to measure volume flow of conducting liquid and slurry in the closed pipeline.
After many years of practical operation.
More flow meter manufacturers choose model price quote you are welcome to inquire, here is how to improve the measuring accuracy of electromagnetic flow meter scale by reducing the article details.
How to improve the measurement precision of the electromagnetic flowmeter by variable diameter we all know that electromagnetic flowmeter measurement principle is Faraday's law of electromagnetic induction, it is mainly used to measure volume flow of conducting liquid and slurry in the closed pipeline.
After many years of practical operation and observation comparative analysis, we believe that in the field of water metering, electromagnetic flowmeter is superior to other measuring instrument.
In practice, often appear due to user nature of water tube flow velocity is low, and can't meet the requirements of electromagnetic flowmeter for velocity range, so this time need to variable diameter pipe processing.
Particular way is, pipes, pipe fittings and valve diameter according to the system integration after using the parameters is selected, select the sensor diameter is smaller than measure the diameter size of electromagnetic flowmeter, that is to say, the table of the measured pipe diameter electromagnetic flowmeter with diameter is not consistent, pipe diameter, table size small, reducer added before and after installing a connection sensors.
As a result the installation local pipeline improves the velocity of electromagnetic flowmeter, meet the requirements of the flowmeter for velocity range.
In variable diameter processing work, must pay attention to the reducer need to meet the requirement of taper.
Electromagnetic flowmeter of inlet and outlet of straight section length requirement, reducer, added before and after the sensor to be seen as part of a straight pipe, should be consistent with the product on the sensor before and after the section of divergent or convergent cone Angle is less than 15 & deg;
When the reducer can't satisfy the requirement of taper, must be custom-made extended divergent or reducing pipe.
Electromagnetic flow meter is used for measurement of water supply, due to its sensors have velocity requirements, but the velocity and the characteristics of wide range, designers can according to user's water consumption and the scene actual situation, make some flexible changes, it saves water meter set of investment, and the flowmeter can run in good working condition.
Electromagnetic flowmeter, by the way, the upstream side should be not less than 5 d pipe diameters of straight pipe, the downstream side should be not less than three times the pipe diameter of straight pipe.
If there are not fully open the gate or valve upstream, the length of the straight pipe upstream of the flowmeter should be increased to 10 times the pipe diameter.
Above is all there is in this article, you are welcome to inquire me manufacturer flowmeter selection, quotation, etc.
At a time when technology is essential for mass flow meter
, ensuring that it works in a symbiotic way with your human employees is key.
Our vision is to realize the tremendous potential of mass flow meter by providing endress hauser coriolis mass flow meter
services that consistently meet our customers’ expectations.
Beijing Sincerity Automatic Equipment Co., Ltd might focus its marketing efforts by highlighting its end product—improved technology and increased profits—not its producing methods.


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By most accounts, Edgar Bronfman, the Seagrams heir and former head of the World Jewish Congress, was the hero of the historic Swiss bank deal. He is widely credited with launching the initiative that eventually led Swiss banks to agree to a $1.25 billion settlement to resolve claims that they hoarded bank accounts opened by Jews who were murdered by the Nazis.
But with the death of Richard Holbrooke last week has come fresh details of the U.S. diplomat’s pivotal and secret efforts in 1996 to convince Swiss banks to take the steps that led to that settlement.
WASHINGTON (JTA) -- Richard Holbrooke, the legendary U.S. diplomat who brokered a Balkan peace and who enjoyed talking about his Jewish roots, has died.
Holbrooke, who was the Obama administration's envoy to Afghanistan and Pakistan when he died, suffered a torn aorta on Friday and was hospitalized. The State Department announced his death on Monday. He was 69.


NUTT, N.M. — For years, Public Enemy No. 1 in these parts was a gray-coated creature called "el lobo." Ranchers and bounty hunters wanted it only one way: dead.
But next year, after years of wrangling between ranchers and the U.S. Fish & Wildlife Service, the Mexican wolf will be free again to roam the cactus-filled range and pine and aspen forests of southern New Mexico and central Arizona.
In the 30 years since the wolf was declared an endangered species, a new breed of rancher has appeared, and though still a tiny minority, the eco-rancher can hardly wait for the wolf to hit the ground.
"The wolf is a part of the land just as much as the wind is," said Jim Winder, 36, whose 18,320-acre ranch in Luna County, N.M.. is just a mile from the Middle of Nowhere Bar & Cafe in Nutt.
Winder was so eager to see the return of the wolf to the ecosystem surrounding his 450 cows that last year he and an unusual coalition of wolf supporters threatened to sue the federal government for taking too long to release the wolves.
The coalition of sportsmen, conservationists, and ranchers was led by the environmental group Defenders of Wildlife.
In March, Interior Secretary Bruce Babbitt signed the order authorizing the release.
The matter boils down to dollars. Winder and fellow ranchers such as Will and Jan Holder across the border in Arizona believe they can make money raising beef in an environmentally friendly way.
Defenders of Wildlife is proposing to stamp "Wolf Country Beef" on their beef products as a kind of Good Housekeeping Seal of Approval, something that could be a useful marketing tool.
The environmental group would help the ranchers market the beef and sell it at a premium to the same socially conscious consumers who scour the supermarkets for "Turtle Friendly Shrimp," "Predator Friendly Wool," and "Dolphin Safe Tuna."
"You can't have `Wolf Country Beef' without wolves," said Winder, who envisions eventually making a living not just from beef, but also from giving guided eco-tours of the range land.
He thinks people will pay to track--just to observe--endangered species like the Mexican wolf and to get glimpses of some of the 100 different species of birds, including the roadrunner of cartoon fame, that nest in the region.
"Almost like Knott's Berry Farm without the rides-- come see where your food supply is produced," Winder said.
Most ranchers think Winder and his kind are nuts.
"I can easily see the wolf putting some people out of business," said Barbara Marks, who co-owns the Marks WY Bar Ranch in Blue, Ariz., with her husband Bill. Blue is in an area where the wolf is to be released.
"If the wolf doesn't come after the cattle, it will put pressure on the other predators to do so," Marks said, adding that a bear recently killed one of their calves.
The biggest problem Marks sees is that the wolves to be released are not used to hunting for their own food, making domesticated animals prime targets.
The Mexican wolf, which roamed the area from prehistoric times, was exterminated in the U.S. in 1976 by ranchers seeking to protect livestock.
It was declared an endangered species, and the Fish & Wildlife Service, with the cooperation of the Mexican government, began tracking and capturing the wolves in Mexico a year later. The wolves were then placed in a captive breeding program.
"Obviously it's a challenge for wolves in captivity to make that leap to freedom," said Wendy Brown, a Mexican wolf recovery biologist, who said the wolves were fed road kill and wild game supplied by volunteer hunters.
But, she said, "the wolves are wild, not habituated to humans or domesticated in any way, so the instincts are there."
The wolves are to be released into the Gila and Apache National Forests in New Mexico and Arizona next year. They will be released in three groups, with two to seven wolves in each group.
The Holders understand the ranchers' concerns.
"For some ranchers, one more cow killed by a predator could mean that their kids may not get braces this year," said Will Holder, 35, who, along with his wife, abandoned a career in advertising and marketing in Phoenix to take over the family ranch, located off a remote dirt road in Apache National Forest.
At the same time, they believe the threat to livestock is slight, particularly if ecologically-sound herding techniques, like those taught at the Santa Fe-based Center for Holistic Resource Management, are followed.
The problem is that less than 1 percent of U.S. ranchers follow these practices, which involve herding cows into small fields and rotating them from field to field almost daily.
Banding the cows in tight-knit groups makes them less appealing prey, yet most ranchers allow their cows to roam over thousands of acres of land, Winder said.
"They let their cows loose and see them maybe once a year," said Holder, whose herding techniques are similar to Winder's.
Winder said they are just following common sense.
"I'm sure 100 women walking down a dark Chicago street at night would be less of a target than one woman walking by herself," Winder said.


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1 head green cabbage
1 lb ground pork (or ground turkey)
1/2 lb ground beef
2 small onions , diced
3 cloves garlic , minced
1/2 teaspoon dill weed
3 tablespoons fresh parsley
1 can (14 oz) diced tomatoes
salt & pepper to taste
1 cup uncooked rice
1 1/2 cups + 1/3 cup tomato sauce or pasta sauce , divided
1 can tomato soup
Boil cabbage leaves about 2 minutes or until soft. (See note below for removing leaves). Set aside to cool.
Preheat oven to 350 degrees.
Cook rice according to package directions but reduce cooking time by 5 minutes so the rice is slightly underdone. Set aside.
Cook beef, pork (or turkey), onions, garlic & seasonings until no pink remains. Drain any fat. Add in rice, diced tomatoes, 1/3 cup of tomato/pasta sauce, salt & pepper. Stir in egg.
Mix tomato sauce and tomato soup in a bowl. Spread a very thin layer of the tomato sauce mixture in a 9×13 pan.
Remove or thin any thick stem on cabbage leaves. Lay the cabbage leaf flat and add 1/3 cup filling to the center of the leaf. Fold in the sides and roll the cabbage up. Place seam side down in the pan. (See note for small leaves). Repeat with remaining cabbage.
Pour sauce over the cabbage and cover tightly with foil. Bake 75-90 minutes. Let cool 15 minutes before serving.

domain: food


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The mum of a three-year-old boy says he has been asked to leave Sunflowers Too Day Nursery in Hessle following her complaints that another boy was repeatedly biting him
Image: Hull Live/MEN)
A young boy has been forced to leave his nursery after his mother complained that he was being bitten.
The three-year-old was repeatedly bitten by another child at Sunflowers Too Day Nursery in Hessle, his mother has claimed.
The assault began within weeks of his enrolment last January, the parent who asked to remain anonymous told Hull Daily Mail.
A number of injuries were catalogued over the coming months, some of which were caused by the boy.
When the mum complained, the other child was removed from the room her son was taught in.
But after the most recent summer holidays they were put back in the pre-school room together without the mother’s knowledge.
It was only when her son came home from nursery with another bite mark and told her the “not nice boy” had done it, that she found out they were together again.
After complaining to the manager she given a day’s notice to remove her child from the nursery after being told her contract has been terminated.
She claims: “My child has been bitten several times at nursery. He tells me this boy is not very nice to him and he upsets him.
“I had a meeting last year and the child was removed from the same [email protected]
She claims he ‘got another bite this week’ and added that ‘he told me who’d done it, and thank goodness he can talk as otherwise I wouldn’t have known he was in the same room as this child, as nursery didn’t tell me.
“I emailed my concerns and I was very upset but I wasn’t rude. I got a reply to say she was terminating our contract and I asked for a meeting and she repeated that she was terminating the contract.
She claims that because ‘they can’t keep my son safe he is getting kicked out of nursery.’
The mum, who is studying to become a teacher, said she has complained to Ofsted and is now having to keep her son at home until a suitable alternative nursery can be found.
“This manager is excluding my child from their friends and education, I had raised serious safeguarding concerns.
“I have taken advice about the matter and was told that if I have legitimate concerns as a parent and have raised them, they should be looking into these instead of terminating my contract.
“I am disgusted that instead of addressing the injuries my son has received they are throwing him out of nursery.
“I have rightfully reported the matter to Ofsted as they have no grounds to rip my son away from his friends and education,” she claimed.
In an email to the parent, the nursery wrote: “On reflection and having taken advice with regard to your concerns about the care (child’s name) is receiving at Sunflowers Too Day Nursery, we have an untenable situation where everything is being questioned and you feel your child is not safe here despite us doing the utmost for all
“I feel the parent-carer relationship has irretrievably broken down and I am therefore, terminating our contract.
“There is a four week notice period, however as you are so disappointed in the service we are providing and absolutely disgusted with my staff, this can be waived.”
A spokesman for the nursery said: “Sunflowers Too Day Nursery have followed all policies and procedures under the Early Years Foundation Stage and safeguarding requirements.
“We are in communication with Ofsted who are our regulatory body and we have informed them all policies and procedures followed are to keep all our children safe at Sunflowers Too Day Nursery.”


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In the case of cross-border processing, you must determine who your lead supervisory authority is.
Cross-border processing is defined as:
Processing of personal data which takes place in the context of the activities of establishments in more than one Member State of a controller or processor in the Union where the controller or processor is established in more than one Member State, OR
Processing of personal data which takes place in the context of the activities of a single establishment of a controller or processor in the Union but which substantially affects or is likely to substantially affect data subjects in more than one Member State.
The GDPR does not define ‘substantially’ or ‘affects’. The intention of the wording was to ensure that not all processing activity, with any effect and that takes place within the context of a single establishment, falls within the definition of ‘cross-border processing’. The most relevant ordinary English meanings of ‘substantial’ include; ‘of ample or considerable amount or size; sizeable, fairly large’, or ‘having solid worth or value, of real significance; solid; weighty, important’. The most relevant meaning of the verb ‘affect’ is ‘to influence’ or ‘to make a material impression on’.
The content herein is provided for your convenience and does not constitute legal advice.
Compliance Technology Solutions B.V. 2018

domain: law


68% Layout Mechanical Keyboard
GK73X is designed with independent F keys, arrow keys and numbers to be more suitable for traditional typing habit. GK73X is equipped with hot swappable terminals, with which you could install the switches directly without soldering. It’s compatible with Cherry MX switches, Kailh switches and Gateron switches. You can easily build up your own mechanical keyboard with this kit.
16.8 Million RGB Backlight
RGB is such a cool element while playing games. GK73X fully knows your needs and thus this model is equipped with RGB SMD light. More than 16.8 million lights are available. RGB atmosphere along with the aluminum alloy case are quite matched beyond your imagination. It’s more than a keyboard but also a fun toy.
Bluetooth 5.1 Wireless&Adjustable Sleep Mode (GK73XS ONLY)
Adopting the latest Bluetooth technology, you can connect up to 4 devices at the same time, simply press FN+Z/X/C to exchange between devices. Press FN+SPACE to switch from wireless mode to wired mode. Added adjustable time in sleep mode supports 10 levels adjustment from zero to 45 minutes. More user friendly and energy saving.
3 Layers Fully Programmable
Custom is not just a word. We make it true. Here you can reach micro settings. Simply download the driver and you will be able to program the backlight and macro settings. Built-in flash memory can save the setting at offline mode, never afraid of losing it.
Professional and Classic Keyboard
GK73X is 68% layout compact and lightweight mechanical keyboard. The chipset is 32 Bit MCU + 8M Flash on-board memory, and 3 pieces independent 256*256*256 RGB color management chip. It’s either good for your office or your game journey.
Type-C Cable&Improved ABS Case
GK73X got all you need for a custom keyboard. Except for the type-c cable for stable and fast connection, the optimized ABS case offers supreme experience and the ultimate elegance to your everyday use. More than that, you even got the music-driven motion effects! In this mode, the backlit will blinks with the music, cool and interesting.
Three Layers Programmable Modes
User Defined Mode
Mac OS Mode
FNX Adjustable Function Define Mode
- Type-C Cable
- Instrustion Manual
Issues with keys changing functions, major issue with R key suddenly getting stuck or no longer functioning. Blu tooth functions are iffy often having trouble connecting
Thank you for leaving a review here.
We are so sorry for the issue you met. You may try a different switch on the R key. As to the bluetooth, we suggest charge the keyboard to the full before start the wireless connection.
If you have met any other problems when using the keyboard, please feel free to contact us by emailing to firstname.lastname@example.org and attaching your order number and a video to show the issue. Our support will be happy to help you out.
Thank you for your understanding.
Essay to mod, really well built and sounds pretty good. I love the 65+numpad format. I recommend!


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Download 30 Awesome Mineral Style Gradients For FREE
Gradient are a great way to add color to your image. They’re simple to create, but add awesome results when adding different variations. There’s many different styles and colors to choose from, This pack included 30 Mineral style gradients that look stunning.
ꜛ Quick tip when adding gradients to your image! ꜛ
When applying a gradient map to your image, there’s a good chance it doesn’t look correct right away. Try changing the blending mode of the gradient to fit your image better.
Mineral Gradients – Created by PhotoshopTutorials.TV
Please do not download and re-upload anywhere else. You’re
Free to use these gradients for commercial and non commercial projects. Please link back to this web-page to respectfully credit the owner.

domain: artistic


text:
British Prime Minister Theresa May told restive lawmakers Monday that military airstrikes on Syria were right both legally and morally, and she accused Syria and its ally Russia of attempting to cover up evidence of a deadly chemical weapons attack.
May faced down her domestic critics as France's premier defended the "proportionate" response to the use of chemical weapons. European Union foreign ministers united to say they understood the need for the airstrikes and called for a new push for a political solution to the war in Syria.
British Royal Air Force jets joined American and French warplanes and ships in hitting targets in Syria early Saturday in response to a reported chemical attack by the Syrian government in the town of Douma.
The British government is not legally bound to seek Parliament's approval for military strikes, although it is customary to do so, and many lawmakers expressed anger that they were not consulted.
May told legislators in the House of Commons that seeking their approval would have been impractical, both because Parliament was on a spring break until Monday and because some of the intelligence behind the decision was classified.
"We have always been clear that the government has the right to act quickly in the national interest," May said, calling the military action "not just morally right but also legally right."
"We cannot allow the use of chemical weapons to become normalized, either within Syria, on the streets of the U.K., or elsewhere," May said — linking the chemical attack in Syria with the poisoning of a former Russian spy and his daughter last month with a military-grade nerve agent in the English city of Salisbury.
Syria and Russia have both denied that Syrian government forces carried out the Douma gas attack, suggesting it may have been staged to implicate them.


Throughout this year, we are celebrating the Year for Consecrated Life. Each issue of The Catholic Mirror has had a story on a different religious community that has served the Diocese of Des Moines. This Sunday, in celebration of this special year, there will be a Mass honoring those in consecrated life who serve our diocese. They will be honored at the 10:30 a.m. Mass on Sunday at St. Ambrose Cathedral. Join us in thanking these men and women for answering their vocational call to religious life and for serving the people of God in southwest Iowa.
Four Iowa bishops support Education Savings Accounts
The four Iowa Catholic bishops urge state lawmakers to adopt legislation that enacts Education Savings Accounts, a tool that allows parents to choose the best and most suitable education for their children regardless of economic standing.
Through ESAs, the state would deposit funds each year in an account that parents of nonpublic school children could access for tuition, fees and tutoring. The funds deposited in the account would be the average state foundation aid per pupil. Schools are typically funded with state aid, local property taxes and federal funds.
The bishops, through the Iowa Catholic Conference, issued a statement urging support for ESAs at the start of Catholic Schools Week, which began Jan. 25.
“The Iowa Catholic Conference, with the support of thousands of Iowans, asks the legislature to enact an ESA program during the 2015 legislative session,” the bishops wrote. “This innovative idea would further level the playing field for parents who lack the resources to choose freely their children’s education setting or who are struggling to keep their children in the school of their choice.”
Iowa is a leader in supporting education choice. For example, the state allows for “open enrollment” for some public school parents, provides the tuition tax credit and offers state-funded preschool. In 2006, lawmakers enacted legislation that established school tuition organizations. Named the Catholic Tuition Organization in the Diocese of Des Moines, this organization accepts donations and assists families that need financial help with tuition so they can choose Catholic schools for their children. This landmark legislation in Iowa was instrumental in allowing parents to choose a school that reflects the convictions of their families. Thanks to the CTO, families can choose top-notch schools with high academic achievement while having their children in a faith-filled educational environment.
“The Diocese of Des Moines and I personally support strong public schools,” wrote Bishop Richard Pates in his monthly column in The Catholic Mirror newspaper. “At the same time, we advocate parental choice in education. Also, in the present environment, we do not want our Catholic schools to become preserves for the elite or wealthy. They should be realistically accessible to all.”
The four bishops signing the statement are: Dubuque Archbishop Michael Jackels, Davenport Bishop Martin Amos, Sioux City Bishop R. Walker Nickless and Bishop Pates.
“The state should respect and support the right of parents to choose the most appropriate education for their children and, as far as possible, make such choosing fair and unimpeded,” the bishops said. “Education Savings Accounts will help give parents the freedom to make a real choice in education.
Pope grants priest’s request for laicization
Pope Francis granted Howard Fitzgerald’s request for a dispensation from the priesthood and the obligation of celibacy on Jan. 19 following a credible allegation that came to the attention of the Diocese of Des Moines last year regarding a decades-old case of sexual abuse.
“I personally met with Howard Fitzgerald and notified him of the Holy Father’s decision to grant his request for laicization. His laicization occurred at the moment of this notification,” said Bishop Pates. “I sent a memo to priests of the diocese and then left for several meetings out of town for the duration of the week. Now that I have returned to Des Moines, I would like to share further information with the people of the Diocese of Des Moines.”
Fitzgerald was placed on indefinite administrative leave last June and could not function publicly as a priest after the diocesan Allegation Review Committee deemed an allegation to be credible. Details of the allegation have not been released at the insistence of the victim. A press release was issued June 30, 2014, shortly after the Allegation Review Committee transmitted its recommendation to Bishop Richard Pates. All parishes in the diocese were notified of the situation, in particular those which he served.
Fitzgerald voluntarily petitioned Pope Francis to release him from the priesthood and sacred celibacy. The diocese has been advised by Fitzgerald’s counselor that he is no threat to broader society. He will be granted three months separation compensation and will have the opportunity to work at a secular job until retirement. He will have access to Social Security and retirement benefits of the diocese in which he is vested. He has indicated that he will be residing with family. Anyone wishing to contact Mr. Fitzgerald should do so through the Catholic Pastoral Center and the communication will be forwarded to him.
After the diocese learned of the allegation, the victim was provided the services of the diocesan Victim Assistance Advocate. Local law enforcement where the alleged abuse occurred and the Allegation Review Committee were immediately informed.
Bishop Pates has apologized to the victim and encourages anyone who may have been sexually abused by clergy to contact diocesan Victim Assistance Advocate Sherry Knox. She is a staff member at Polk County Victim Services. She assists victims through the complaint process and in seeking support and counseling services. Knox can be reached at 515-286-2028 or email@example.com.
Bishop Pates said it is a top priority of the Diocese of Des Moines to provide a safe environment for children and to comply with the Charter for the Protection of Children and Young People, a document approved by the U.S. bishops in 2002 that offers a comprehensive set of guidelines on reporting sexual abuse, accountability, reports to a national board and mandatory education programs in parishes and schools.
Consejero sobre Asistencia de Victimas El Consejero sobre Asistencia de Víctimas es un empleado de Polk County Victim Services. Ella ayuda a víctimas de abuso sexual por parte del clero durante el proceso de la queja y buscando servicios de apoyo y consejería. Pueden comunicarse al 515-286-2028 o en firstname.lastname@example.org.


China's vavle market is getting worse and worse,mainly because there is no innovation.Petrochemical industry the main application of API standard gate valve, globe valve Plug valve, ball valve ,and check valve;Power sector mainly adopts power station with high temperature and pressure gate valve, globe valve, check valve and relief valve, and part of the water supply and drainage valve of low pressure butterfly valve, gate valve;Chemical industry mainly adopts stainless steel gate valve, globe valve, check valve, breathing valve, flame arresters, filters, pipes, sight glasses, etc.Metallurgical industry mainly adopts low voltage large diameter butterfly valve, oxygen cut-off valve and ball valve, valve, breathing valve, flame arrester;Urban construction department mainly adopts low-pressure valve, such as urban tap water pipeline mainly adopts large-diameter gate, building construction mainly USES the center line butterfly valve, city heating mainly adopts metal sealing butterfly valve;Pipeline mainly adopts flat gate valve and ball valve;The pharmaceutical industry mainly adopts stainless steel ball valve, breathing valve valve, flame arrester;Food industry mainly adopts stainless steel ball valve, breathing valve valve, flame arrester, etc.
About valve products market, according to the analysis, in the next period of time the main trend is as follows:
1. As the oil development to the mainland oil fields and the transfer of offshore oil field, as well as the electric power industry from 300000 kw to 300000 kw thermal power under the above of the thermal power and hydropower and nuclear power development, the respiration valve, flame arrester, filters, pipes, sight glasses, and other products should be based on equipment application domain changes to change its properties and corresponding parameters.
2. Urban construction system generally USES a large number of low pressure valves, and to the development of environmental protection and energy-saving, namely by the use of low iron gate toward environmental protection rubber sheet, balance valve, the transition metal sealing butterfly valve and the midline sealing butterfly valve.Oil and gas engineering to develop in the direction of pipelining, it requires a lot of flat gate valve and ball valve.
3. The other side of the energy development is energy saving, so in terms of energy conservation, to develop the steam trap, and high toward the subcritical and supercritical parameter.
4. The construction of the power station to large-scale development, so the need of large diameter and high pressure relief valve and pressure reducing valve, at the same time also need quick opening and closing valves.
5. Package engineering needs, the supply valve by a single species to more varieties and specifications.A project required valve, provided by a valve manufacturer all trend is getting bigger and bigger.


, which is why they decide to enter into secret transactions with unverified sellers who do not have a good reputation. We think the price is so tempting that you can risk transactions with such people, turning a blind eye to their not very good grades. But such things are worth forgetting. Especially if the workshop has had a good reputation so far. Bad and misplaced purchases when it comes to vehicle parts can cause the garage's assessment to suffer, and thus - customers will start to leave. American cars are really valuable and it is worth remembering if someone wants to repair them. Especially if you don't have the professional experience of mechanics.
Fortunately, in Poland you can find
American cars in many cases have a charm that is hard to resist. Any real enthusiast of everything related to cars will surely know what's going on. However, this does not change the fact that in practice, owning an American car is not without its complications.
These complications arise mainly when it is necessary to repair such a car. Usually parts for US cars have to be taken straight from America. Fortunately, in Poland you can find companies that specialize in this type of orders. For each of their customers, they will ensure fast and fully safe shipment of parts for the selected car model. They are fully original and will certainly work when repairing a defect. And although such orders are not cheap, companies try not to set very high costs for their services. Thanks to this, every owner of an American car can be sure that, despite the difficulties, it will always be possible to repair his beloved car.
If you don't know how to go
Do you dream of a car that is unique, exceptional and different than you can find in Poland? In 2020, anything is possible! Many websites may allow you to import parts for cars from the USA. They work cheaply and quickly. Just choose your dream American car. Something from the 50s? Or maybe a pimped up Chevrolet Camaro? On many sites you can find cars at good prices with all the information and technical data. The advantage is also a lot of discounts that occur on such websites. If you do not know how to go about such a purchase, there are suitable websites on the Internet for this. All you need to do is call or write! No matter what city in Poland you are from, everything can be arranged! You just have to decide if you want genuine and new parts or used. All you have to do is express your own need. Everything can be arranged quickly and easily. American cars in Poland? Nothing easier! Class and luxury symbol at your fingertips. Search for data on the internet!
Are overseas cars unique?
Real automotive enthusiasts can drive hundreds of kilometers just to have their dream accessories for the car. It may be considered an exaggeration, but it is they who, choosing parts for cars with great care, enjoy many years of operation of the machine without major problems. For some it is an obsession, for others - saving. And it's hard not to agree with the other side.
American cars are considered true miracles of technology. Like ordinary cars, but they combine features that every enthusiast appreciates, including:
- comfort of use.
Hardly anyone can resist such a mixture. However, with the entire exterior of an ideal vehicle, you should not forget about the appropriate selection of parts for US cars. The original assortment is a peace of mind and again - an investment for years and money saved (a larger amount spent once in a long time).
Are overseas cars unique? Certainly, such are the solutions for fans of solutions with panache and diversity.


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Heat 2 tablespoons avocado oil on medium high in a large skillet or wok. Add diced onion and frozen vegetables, and sauté until onions are almost translucent, about 3 minutes. Move the vegetables to the side of pan. Crack eggs into pan and scramble with a spatula until cooked through and fully scrambled.
Add 4 cups cooked rice and 4 tablespoons butter. Cook for 5 minutes and stir frequently. Add 4 tablespoons soy sauce and cook 1 additional minute. Pack fried rice firmly into bowls to keep hot.
For the Chicken and Vegetables (Made Simultaneously)
For the chicken: Heat 1 ½ teaspoons sesame oil and 1 tablespoon avocado oil in same skillet or wok used for fried rice. Add chicken, 3 tablespoons soy sauce, 1 tablespoon butter, lemon juice, salt, and pepper to skillet. Cook chicken until it is no longer pink, about 5-7 minutes. Stir only once or twice so chicken will brown.
For the vegetables: In a separate large skillet or wok, heat 1 ½ teaspoons sesame oil and 1 tablespoon avocado oil on medium high heat. Add sliced onion, baby bella mushrooms, zucchini, 1 tablespoon butter, 1 tablespoon soy sauce, salt, and pepper to skillet. Sauté until vegetables are tender, about 6-8 minutes.
For the Mustard Sauce
Lightly toast sesame seeds if desired. (See note.) Blend sesame seeds, dry mustard, 2 teaspoons honey, 4 tablespoons soy sauce, half and half, hot water, and minced garlic in blender.
For the best fried rice: Do not cook rice immediately before making fried rice. Leftover or precooked rice from the store works best.
For mustard sauce: Lightly toasting sesame seeds will enhance the flavor, but it is not necessary. Mustard sauce can be made ahead of time and stored in the refrigerator.
To make grain-free: Substitute rice with cauliflower rice.
Recipe yields approximately 6 servings. Actual number of servings will depend on your preferred portion sizes.Nutritional values shown are general guidelines and reflect information for 1 serving out of 6 using the ingredients listed. Actual macros may vary slightly depending on specific brands and types of ingredients used.To determine the weight of one serving, prepare the recipe as instructed. Weigh the finished recipe, then divide the weight of the finished recipe (not including the weight of the container the food is in) by 6. Result will be the weight of one serving.


High-speed laser marker is designed for high-speed precision application of marking images (text, graphics, etc.) on a wide range of materials and products. It can also be used for cutting thin metal foils, semiconductor and ceramic plates.
The laser marker model is based on a diode-pumped fiber laser and includes a scanning head based on high-speed laser-deflectors, a vertical displacement unit for the scanning head, a control unit for the scanning head and a vertical displacement unit, and software for controlling the laser marker.
- laser type: pulsed ytterbium fiber with air cooling
- wavelength: 1060 ± 10 nm
- pulse repetition rate: 20 – 100 kHz
- pulse duration: 100 ± 10 ns
- pulse energy: 0,5 mJ
- average output power: 10 W / 20 W
- power usage: 120 W / 150 W / 240 W
- marking area: 60×60 mm / 110×110 mm / 175×175 mm
- weight: 35 kg
- overall dimensions: 640×500×600 mm
- type of images: contour, raster, text, graphic, etc.
Examples of the resulting halftone images and text:


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Sometimes success begins by taking a mighty leap of faith. Sometimes, but not very often. Most often, success begins with one small step.
As small a step as it often is, many people just can’t make themselves take it. They might see success somewhere on the path they want to take but it appears to be a long way off. Between where they are standing and the success they seek are obstacles called risk, failure, effort, problems, lack of financing and other various unknowns.
Those obstacles cause many people to wait. To wait for the obstacles to magically disappear. To wait for someone or something to remove the obstacles for them. These people have a desire for success but their desire is small when compared to what they have told themselves are huge obstacles.
But here’s a funny thing about obstacles on the path to success…the closer you get to them the smaller they turn out to be.
But sadly, many people will not get to experience that because they never take that one small step that starts them down the path to success.
The journey of your success will always begin with the small step of taking a risk. Whether in business, in personal relationships, or in life, all success most often starts with that small step made with a hefty desire to be more. To be better. To make a difference. To leave behind a legacy that’s not soon forgotten.
Despite what you may have heard or hoped, success in NOT available to everyone who wants it. It is only available to those who are willing to work to achieve it. That work includes overcoming any and all obstacles. That work includes maintaining a “can do” attitude, even when you’re surrounded by a pack of “can’t do” people. That work includes making an effort every day, not only on the days you feel like it.
That work includes taking one small step on the path towards success. Sometimes that’s the hardest work of all. The question isn’t whether you want success, the real question is whether you’ll work hard enough to achieve it.
Well, will you?


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Weird Mars Rover rover photographs a strange structure on mars! flash news Mars Rover Weird
We found 21++ Images in Weird Mars Rover:
Top 15 page(s) by letter W
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Weird Mars Rover
Weird Mars Rover What The Hell Is This Weird Shiny Object On Mars Rover Mars Weird, Weird Mars Rover 39alien Faces39 In Nasa39s Mars Rover Photos Subject Of Rover Mars Weird, Weird Mars Rover Shadow Of Man On Mars Seen In Nasa Rover Photo Houston Mars Weird Rover, Weird Mars Rover Rover Photographs A Strange Structure On Mars! Flash News Mars Rover Weird, Weird Mars Rover Mars Curiosity Rover Finds Egg Shaped Meteorite On Red Planet Weird Mars Rover, Weird Mars Rover Curiosity Rover Finds Strange Features On Mars Mars Weird Rover, Weird Mars Rover Latest Curiosity Rover Discovery Strange Looking Rock Rover Mars Weird, Weird Mars Rover Strange Alien Artifact Object In Mars Rover Photo! Can You Mars Rover Weird, Weird Mars Rover Nasas Curiosity Rover Spots Strange Geological Feature On Rover Mars Weird, Weird Mars Rover Strange Unnatural Rock On Mars July 7 2013 Rover Weird Mars, Weird Mars Rover Nasa39s Curiosity Rover Does An About Face To Reexamine Rover Weird Mars, Weird Mars Rover Nasa39s Curiosity Rover Is Finding Some Strange Objects On Mars Rover Weird, Weird Mars Rover Mars Rover Curiosity Has Spotted A Weird Metallic Mars Rover Weird, Weird Mars Rover Aliens Latest Truth About 39lizard Like Creature39 Found On Weird Mars Rover, Weird Mars Rover Ufo Sightings Daily Strange Animal Found On Mars In Nasa Weird Rover Mars, Weird Mars Rover Weird Object Found On The Surface Of Mars Weird Rover Mars, Weird Mars Rover Curiosity Rover Finds Strange Shiny Object On Mars Cbs News Weird Mars Rover, Weird Mars Rover Strange Figure Spotted By Mars Curiosity Rover Fox News Rover Mars Weird, Weird Mars Rover Ufo Sightings Daily Monkey On Mars! Amazingly Weird And Rover Weird Mars.
Christian folklore claims the Man in the Moon is Cain, the eternal Wanderer, doomed forever to circle the Earth. In addition, there is a Talmudic tradition that says it is the face of Jacob etched out on the gleaming lunar disk.
Earth's mysterious large Moon is our nearest neighbor in space, dominating our clear night sky with its beguiling and bewitching cold golden glow. Earth's Moon is the only body beyond our planet that we have visited, leaving our footprints embedded in its alien dust. Despite its close proximity to our planet, our mysterious Moon has still managed to keep some ancient secrets from us very well. However, in October 2014, using data derived from NASA's Gravity Recovery and Interior Laboratory (GRAIL) mission, a team of planetary scientists announced that they may have solved a lunar mystery almost as old as our Moon itself.
Phases and Tides. A strong initial attraction between two people, including the warm glow of new romance, can often arise from heavenly bodies other than the Moon. Chemistry involving fiery planets, such as the Sun or Mars, will often spark a romance-but what makes it truly last?
- Stars and Galaxies Cartoons Ideas
- Asteroid House
- Kerbal Space Program Start Screen
- NASA High Resolution Lighting
- NASA Warns Catastrophic Sun Storm
- NASA Johnson Space Logo
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- Space Galaxy Cat Lanyard
- 2001 Space Station Model
- Apollo Space Launch
- Endeavour Space Shuttle Model
- Hoka Hubble
- YouTube Hubble Ultra Deep Field
When the American astronomer James Christy discovered Pluto's largest moon Charon back in 1978, astronomers were quick to calculate the mass of the system. Pluto's mass was hundreds of times smaller than the mass originally estimated for it when it was first discovered in 1930. With Charon's discovery, astronomers suddenly acquired a new understanding that something was fundamentally different about Pluto.
have been fishing for more than twenty five years for all of the main species of freshwater fish including; trout, walleye, large and small mouthed bass, catfish, pike, and even muskie and in that time have learned one simple fact that has helped me become a much more successful angler. That fact is that the weather and moon have an incredible impact on the activity level of fish and the more active the fish are, the more apt the are to bite your offering when you are fishing.
Titan has a radius that is about 50% wider than Earth's Moon. It is approximately 759,000 miles from its parent-planet Saturn, which itself is about 886 million miles from our Sun--or 9.5 astronomical units (AU). One AU is equal to the average distance between Earth and Sun, which is 93,000,000 miles. The light that streams out from our Star takes about 80 minutes to reach Saturn. Because of this vast distance, sunlight is 100 times more faint at Saturn and Titan than on Earth.


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How Long Does Ketamine Work to Treat my Depression?
Many people wonder how long they can expect the therapeutic benefits of ketamine to last. Although the answer to this question is patient-specific and still under investigation, we can look at current research to help us establish a rough estimate. A 2021 meta-analysis published in the Journal of Psychopharmacology pooled data from multiple studies to assess the overall effect size of ketamine treatment at two, four-, and six weeks post-treatment. This meta-analysis showed that people receiving ketamine treatment for depression can continue to expect significant relief at the two-week mark, with diminishing but still substantial effects at four- and six weeks post-treatment.
According to current evidence, the best way to prolong the antidepressant effects of ketamine is to receive a series of initial treatments followed by maintenance or "booster" treatments scheduled at regular intervals. These booster treatments can help extend the duration of relief and maintain treatment gains over time. Many patients who respond to Ketamine treatment will find they feel best if they receive a "maintenance" ketamine treatment every 1-3 months. Some patients find that their depressive symptoms respond well to the 6 initial treatments and do not require additional treatments. The exact schedule varies depending on patient preference, degree of symptom relief, and many other patient-specific indications.
The exact duration of relief from depression following ketamine treatment can vary depending on the number of sessions, individual response, and severity of the depression. Ketamine's rapid onset can provide much-needed relief for someone during a major depressive episode, reducing the risk of self-harm and improving quality of life. Perhaps even more importantly, ketamine treatments can buy time to allow for other interventions to take effect, such as antidepressants, therapy, and lifestyle changes.
A 2016 randomized trial illustrated ketamine's ability to hasten the response time to antidepressant treatment, which typically takes 6 to 12 weeks. Twenty-seven patients with depression, including treatment-resistant cases, were given either a single infusion of ketamine or a placebo alongside newly initiated Lexapro. Results showed that 92% of patients treated with ketamine in conjunction with Lexapro responded well to treatment, compared to 57% with placebo, with an average response time of 6 days versus 27 days, respectively. The findings of this study demonstrate ketamine's ability to provide swift relief, granting additional treatments the necessary time to take effect.
Reach out to Wellness Psychiatry for questions about ketamine treatment or if you want to set up a consult:
Chen, M.-H., Wu, H.-J., Li, C.-T., Lin, W.-C., Tsai, S.-J., Hong, C.-J., Tu, P.-C., Bai, Y.-M., Mao, W.-C., & Su, T.-P. (2021). Is one or two infusions better in the first week of low-dose ketamine treatment for medication-resistant depression? A post hoc pooled analysis of randomized placebo-controlled and open-label trials. Journal of Psychiatric Research, 144, 448–454. https://doi-org.frontier.idm.oclc.org/10.1016/j.jpsychires.2021.11.006
Conley, A. A., Norwood, A. E. Q., Hatvany, T. C., Griffith, J. D., & Barber, K. E. (2021). Efficacy of ketamine for major depressive episodes at 2, 4, and 6-weeks post-treatment: A meta-analysis. Psychopharmacology, 238(7), 1737–1752. https://doi-org.frontier.idm.oclc.org/10.1007/s00213-021-05825-8
Hu, Y.-D., Xiang, Y.-T., Fang, J.-X., Zu, S., Sha, S., Shi, H., Ungvari, G. S., Correll, C. U., Chiu, H. F. K., Xue, Y., Tian, T.-F., Wu, A.-S., Ma, X., & Wang, G. (2016). Single i.v. ketamine augmentation of newly initiated escitalopram for major depression: results from a randomized, placebo-controlled 4-week study. Psychological Medicine, 46(3), 623–635. https://doi-org.frontier.idm.oclc.org/10.1017/S0033291715002159

domain: psychology


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The Vatican is prepared for a huge crowd Tuesday as Pope Francis hosts political leaders from 130 nations and representatives from a variety of religions for his installation Mass.
Hundreds of thousands of people are expected to pack St. Peter's Square for the celebration, which formally installs Francis as the new leader of the world's 1.2 billion Roman Catholics.
Among the high-level guests, the spiritual leader of the world's Orthodox Christians, Bartholomew, is expected to attend. He would be the first patriarch from the Istanbul-based church to witness a papal inauguration since the two branches of Christianity split nearly 1,000 years ago.
More than 30 delegations of other Christian churches, as well as representatives from the Jewish, Muslim and various other faiths, also will attend.
Argentine President Cristina Fernandez de Kirchner arrived prior to Tuesday, in order to meet with the new pope, who hails from her country. U.S. Vice President Joe Biden, a Catholic, also is one of the political leaders in attendance.
The Vatican released Pope Francis' new coat of arms, which is similar to the one he used as Archbishop of Buenos Aires. It features symbols of Jesus, his mother Mary and her husband Joseph, as well as the new papal trappings of a bishop miter and the crossed keys of the Holy See.
Vatican officials also released details of Francis' official ring, which once was offered to Pope Paul VI, who presided over the second half of the Second Vatican Council, which is credited with modernizing the Roman Catholic Church.
Francis will receive the ring during Tuesday's installation Mass.


text: A Destiny to Die For (Book I) Angelita grabs at a chance to get out of the favelas when she finds a huge cache of heroin. Money becomes no object, so much so, it seems too good to be true. It is! The drugs belong to the cartel. See price on Kindle.


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Educating Instead of Medicating
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