text:
SubZero - Ultra Salts (Halo)
An e-liquid that exhibits an intense, cool mint effect more powerful than any of our other menthol flavors. This nic salt version has a longer-lasting nicotine effect, low vapor production, and a glacier-fresh finish, so you can chill with the frigid flavor of SubZero all day.
WARNING: THIS EJUICE CONTAINS SALT NICOTINE
Nicotine Salt, Salt Nicotine or Nic Salt is the naturally occurring state of nicotine found in tobacco. E-liquid with extracted nicotine salt is known to more closely emulate the nicotine absorption rate of traditional smoking, while providing a smoother inhale.
Nicotine Salt e-liquid is a great option for new vapers, or those using low wattage (<20W) mouth-to-lung vape devices. Because of the higher concentration of nicotine found in Salt Nic eJuice, it is not recommended for high wattage or sub-ohm vape devices.
|Halo (Nicopure Labs LLC)

domain: chemistry


text:
12 Pennywell Road,
No one has favorited this theater yet
Located in the St. Phillips district to the north of the city centre. The Vestry Hall was taken over by Ralph Pringle and he opened this venue as Pringle’s Picture House on 18th October 1908. Taken over by A.B. Atkinson around 1920, it became the Vestry Hall again.
Around 1930 it was equipped with a RCA sound system. The Vestry Hall was closed as a cinema in 1954.
It went over to industrial use and in 2014, is unused.
Just login to your account and subscribe to this theater

domain: history


text:
Just a half-block from Pacific Beach, this San Diego hotel offers a daily continental breakfast. The spacious guest rooms include cable TV.
The simply styled rooms at PB Surf Beachside Inn include private bathroom and air conditioning. A telephone is also provided.
Barbecue grills are available for guest use. Guest laundry services are also offered.
SeaWorld San Diego and La Jolla Museum of Contemporary Art are each less than a 10-minute drive from PB Surf Beachside Inn. The San Diego Zoo is a 20-minute drive away.
Upon check-in photo identification and credit card is required. All special requests are subject to availability upon check-in. Special requests cannot be guaranteed and may incur additional charges. Guests are required to show a photo identification and credit card upon check-in. Please note that all Special Requests are subject to availability and additional charges may apply.

domain: travel


text:
Back Long Dress
Arts & Science Back Long Dress in Midnight. Luxurious, fine silk, wool and cashmere blend gabardine cloth. Oversized style. V-neck front with rounded back. Short sleeves. Side seam pockets. One size. Total length 45”. 62% silk, 22% wool, 16% cashmere. Made in Japan.
Arts & Science was founded by Sonya Park in Tokyo, Japan in 2003. Her work is based on "genuine quality" that gains in value and beauty with age and time. The shapes are inspired by men's, vintage, work and ethnic wear. High-quality, beautifully aging materials combined with highly skilled crafts work of Japanese artisans produce this line that is truly modern luxury.
One size. Our model is 5’10”.
Dry clean only.

domain: artistic


When there's a potential tornado threat to Dallas-Fort Worth, outdoor sirens let residents know, but not every Texas city operates the same warning system.
The city of Dallas has 162 sirens to warn residents about an imminent weather emergency. Fort Worth has 153. But Austin, Houston and San Antonio have gone a different route.
Austin Miller was born in downtown Dallas and grew up in Richardson and Garland, before moving to Houston. While living in the Houston area — first in Sugar Land and later in Cypress — Miller noticed the absence of the sirens he had grown used to in North Texas.
Miller wanted to know: Why don't some areas in Texas have outdoor warning sirens? Miller's question is part of Curious Texas, an ongoing project from The Dallas Morning News that invites you to join in our reporting process. The idea is simple: You have questions, and our journalists are trained to track down answers.
Cities have different reasons for skipping the sirens, but all have one common denominator: Technology makes them unnecessary.
In San Antonio, "tornado sirens are not a good fit" for a community of more than 400 square miles, according to the city's office of emergency management website.
The site says the last three tornadoes in San Antonio didn’t show up on the area’s National Weather Service radar “making it all the more difficult to deploy a siren as a warning tool.”
Instead, the office suggests residents use radio, TV and social media, as well as weather radios to get their alerts.
Angel Flores, spokesman for the Austin Office of Homeland Security and Emergency Management, told the Austin American-Statesman that it would be "very expensive to build, develop and operate" a community siren warning system. The University of Texas at Austin has its own siren system, but the city itself does not.
Along with social media, radio and TV, Austin-area residents can also subscribe to WarnCentralTexas.org to receive emergency alerts.
In Houston, where Miller lived before returning to Dallas in 2016, the metropolitan area is too sprawling to have an outdoor siren system, according to Cory Stottlemyer, spokesman for the Houston Office of Emergency Management.
Instead of using sirens, Houston — like many other cities — can send mass warnings similar to Amber Alerts to residents. The city's system, Alert Houston, has the capability to geo-target specific areas within the city.
"This way we're not clogging people's inboxes and phones" if they are not impacted by an emergency, Stottlemyer said.
Dallas' sirens aren't just for tornadoes. They can also be activated for weather emergencies such as a severe thunderstorm warning with winds topping 70 mph or reports of hail 1.5 inches in diameter or larger, according to the Dallas Office of Emergency Management.
In Fort Worth, sirens can also be used in the event of a chemical spill emergency, a funnel cloud report by a reliable source, or a state or national emergency, according to the city’s emergency management office.
When sirens go off, those outside should immediately seek shelter in an interior room. Once in a safe location, the Dallas emergency office suggests checking local media for updates, and calling local fire or police only if immediate assistance is needed.
In Dallas and Fort Worth, the sirens are typically tested at noon on the first Wednesday of the month, when weather permits.
While outdoor sirens serve an important purpose, they can also be an annoyance if they malfunction. In April 2017, Dallas' outdoor warning siren system was hacked, causing sirens to blare for almost an hour in the middle of the night.
What do you wonder about the weather in Texas?
You can send us your Curious Texas questions by texting “DMN” to 214-817-3868. Follow the prompts and introduce yourself to us, share your story or questions, and we’ll text you with information as we report the story.


Jennifer Herzig Piano, Violin
Jennifer holds a Bachelor of Music in Violin Performance from the University of Illinois as well as a Master of Music from the Longy School of Music. She made her European debut as soloist with the National Philharmonic of Ukraine in Kiev in 2010, and also has extensive chamber and orchestral experience. In addition to being a violinist, Jennifer is also an accomplished pianist. She studied piano for over 13 years and regularly performs as an accompanist and church musician. Jennifer has experience teaching piano and violin to both children and adults bringing a creative and energetic approach to traditional methods.
Syliva Schwartz Piano, Violin
Fascinated and inspired by the relationship between music, movement, and dance, violinist and Dalcrozian-in-training Sylvia Schwartz is a passionate chamber musician in both modern and historical performance practices. Sylvia performs currently with the New Bedford Symphony Orchestra, Eudaimonia baroque orchestra, L’Esprit Baroque chamber ensemble (Los Angeles), folk/baroque band Lizzie and the Flakjackets, and prog/alt rock band The Mood Swings. Sylvia is equally passionate about bringing music to life as a performer and nurturing creative expression and empowerment in her violin, piano, and musicianship students. She uses a combination of Suzuki approaches, improvisation, Dalcroze-inspired eurythmics, and Alexander Technique-inspired movement awareness to simultaneously develop fluent musicality, joy in making music, a solid instrumental technique, and musicianship. A former sufferer of tendonitis, she has a particular interest in addressing and preventing performance injuries, in both beginning and experienced players. She holds a Master of Music in Violin Performance from Longy School of Music and a Bachelor of Science in Engineering from Olin College.


Sep 30, 2023, 4:54pm CEST
Across the Romaverse #148: Mixed Results Against Genoa & Frosinone, Upcoming Calendar and Conte Rumors
With Roma's recent results all over the map, a jam-packed fixture list and Antonio Conte circling the club, there's plenty to discuss!
Serie A 2023-2024, Giornata VII
After a shocking performance earlier this week, Roma sits in 16th place on the table. With the pressure mounting, can José Mourinho turn things around?


text:
Wednesday, 30 September 2009
The overwhelming "to be read" pile
I have definitely bought fewer books this year but in spite of that my pile of books waiting to be read just grows and grows. Just on the shelves near my computer are the following: A Most Wanted Man – John Le Carre If it Bleeds – Duncan Campbell Love in a Cold Climate – Nancy Mitford Woman on the Edge of Time – Marge Piercy Brave New World – Aldous Huxley Millennium – Tom Holland A Fraction of the Whole – Steve Toltz Beowulf – Seamus Heaney Little Dorrit – Charles Dickens The Master and Margarita – Mikhail Bulgakov The Dancer Upstairs – Nicholas Shakespeare The Bell Jar – Sylvia Plath Anna Karenina – Leo Tolstoy U.S.A. – John Dos Passos Heart of Darkness – Joseph Conrad Surfacing – Margaret Atwood Oryx and Crake – Margaret Atwood Sacred Games – Vikram Chandra We Are Now Beginning Our Descent – James Meek Hearts and Minds – Amanda Craig 2666 – Robert Bolana The Secret Scripture – Sebastian Barry Master Georgie – Beryl Bainbridge True History of the Kelly Gang – Peter Carey The Good Soldier – Ford Madox Ford Such a Long Journey – Rohinton Mistry The Collection – James Crumley Falling Angels – Tracy Chevalier And there are even more in the rest of the house! So, no more new purchases before the end of the year. Well, not many anyway!

domain: literature


text:
For those who are in the fence of filing a bankruptcy, be sure to identify first the possible effects or consequences that comes with it. It is best to consider first with a bankruptcy lawyer on what will be the legal process, not to mention, the possible fees that one will incur during the process. So, does filing bankruptcy can solve your financial woes? It could. But, it might not also be the lone answer.
Bankruptcy can turn one person’s world upside down. A single mishap or bad handling of financial could have long term effect on one’s livelihood. What can bankruptcy do for you? Filing a bankruptcy before court means you all collections agency will put a halt on collecting their sum of money to you. Forever. But it has certain exemptions such as tax liabilities and child support obligations will still be collected from you. Not to mention, filing such will not affect your credit score as you will have a fresh start and could potentially boost your score when you do good compared before filing a bankruptcy.
But, there are will be a downside when filing a bankruptcy. One of which is a possible loss of property. This will apply if the value of the property or item that is being foreclosed is lower than the actual value of the item being foreclosed. Another downside is your privacy will be open to court’s reference. This is a major red flag for some as your private information will be available anytime for viewing under court’s order.
If happen you are looking for a competitive and reliable bankruptcy lawyer, BLC Law Center in San Diego is the place to be for your bankruptcy related concern. With combined 100 years of experience, BLC Law Center is the number one choice.

domain: law


text: Quick library search: Limit by: On Shelf All formats Books eBooks Books on CD eAudiobooks Playaways Graphic Novels Magazines and Newspapers Music CDs Music CDs - Children's DVDs DVDs - Children's 2019 Reading Challenge Amazon adventure : how tiny fish are saving the...Montgomery, Sy, author. Birdology : adventures with a pack of hens, a p...Montgomery, Sy. Chasing cheetahs : the race to save Africa's fa...Montgomery, Sy. Encantado : pink dolphin of the AmazonMontgomery, Sy. The good good pig [audiodisc]Montgomery, Sy, author. The good good pig : the extraordinary life of C...Montgomery, Sy, author. The Great White shark scientistMontgomery, Sy, author. How to be a good creature : a memoir in thirtee...Montgomery, Sy, author. How to be a good creature [audiodisc] : a memoi...Montgomery, Sy, author, na... How to be a good creature [AudioEbook] : a memo...Montgomery, Sy, author. How to be a good creature [eBook] : a memoir in...Montgomery, Sy, author. 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The tarantula scientistMontgomery, Sy. Temple Grandin : how the girl who loved cows em...Montgomery, Sy. Recently Added DVDs A-X-L [DVD] The adventures of Tintin. Season two [DVD] The bold type. Season two [DVD] Castle in the sky [DVD] Chucky [DVD] : the killer DVD collection Colette [DVD] Family guy. Season sixteen [DVD] First man [DVD] Geostorm [DVD] Halloween [DVD] The hate u give [DVD] Hell fest [DVD] The Italian job [DVD] Mid90s [DVD] Night school [DVD] The nun [DVD] The old man & the gun [DVD] One true thing [DVD] Operation finale [DVD] Opry video classics. Duets [DVD] Opry video classics. Hall of fame [DVD] Opry video classics. Honky-tonk heroes [DVD] Opry video classics. Legends [DVD] Opry video classics. Love songs [DVD] Opry video classics. Pioneers [DVD] Opry video classics. Queens of country [DVD] Opry video classics. Songs that topped the char... Our cartoon president. Season one, with world c... Puppy dog pals. Playtime with puppy dog pals [D... Ready jet go! 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domain: library


text: In the new musical Flashdance, Alex Owens is supported by her tightknit group of girlfriends as they work as dancers at a Pittsburgh dive bar. Kelly Felthous plays Gloria, Alex’s bubbly best friend, who travels down a different road than the strong-willed Alex. Felthous, who says she is “a bit lost at times,” like her character, describes what it’s like to be in the national tour in the video below. See what the actress had to say about “living in her own fantasy world” on stage, being dramatic like Gloria and her how classic Hollywood stars inspire her. Flashdance is currently playing Baltimore’s Hippodrome Theatre through February 17.


text:
Discover the Vibrant City Life of London : Iconic Landmarks, Diverse Neighborhoods, and Lively Markets (2024)
London, the capital city of the United Kingdom, is a vibrant metropolis that never fails to captivate visitors with its dynamic atmosphere and rich cultural tapestry. From historic landmarks to modern attractions, this bustling city offers a kaleidoscope of experiences for travelers of all interests.
Discover the Vibrant City Life of London: Iconic Landmarks, Diverse Neighborhoods, and Lively Markets
Join us as we delve into the vibrant city life of London, exploring its iconic attractions, diverse neighborhoods, world-class entertainment, and lively markets that showcase the true essence of this cosmopolitan hub.
1. Tower Bridge and the River Thames :
Begin your London adventure with a stroll along the banks of the River Thames, where you’ll encounter the iconic Tower Bridge. Admire the stunning architecture, cross the walkways suspended high above the river, and enjoy panoramic views of the city skyline. Don’t forget to capture the perfect photo of this symbol of London’s grandeur.
2. Buckingham Palace and Changing of the Guard :
No visit to London is complete without witnessing the Changing of the Guard ceremony at Buckingham Palace. Marvel at the royal splendor of this official residence of the British monarch, explore the surrounding gardens, and immerse yourself in the regal atmosphere that permeates the area.
3. Covent Garden :
Experience the vibrant energy of Covent Garden, a cultural hotspot known for its street performers, boutique shops, and lively atmosphere. Explore the market’s charming stalls, indulge in delectable street food, and catch a mesmerizing performance at the Royal Opera House. Covent Garden offers a delightful blend of history, shopping, and entertainment.
4. Camden Town :
Immerse yourself in the eclectic and alternative vibes of Camden Town. This vibrant neighborhood is a haven for artists, musicians, and fashion enthusiasts. Stroll through the famous Camden Market, browse unique vintage boutiques, and savor international cuisine at the food stalls. Don’t miss the iconic Camden Lock and its picturesque canals.
5. West End and Theatreland :
Indulge in world-class entertainment in London’s West End, also known as Theatreland. Catch a captivating musical or a gripping play at one of the renowned theaters. From timeless classics to cutting-edge productions, the West End offers a diverse range of performances that will leave you spellbound.
6. Notting Hill and Portobello Road Market :
Step into the colorful world of Notting Hill, famous for its charming pastel-colored houses and the vibrant Portobello Road Market. Discover an array of antiques, vintage clothing, and quirky treasures as you wander through the market stalls. The annual Notting Hill Carnival, celebrating Caribbean culture, is a lively event not to be missed.
7. Southbank and the London Eye :
Take a leisurely stroll along the Southbank, a cultural hub that offers stunning views of the River Thames and London’s skyline. Visit the iconic London Eye, a giant Ferris wheel that provides breathtaking panoramic vistas. Explore the Southbank Centre, home to art exhibitions, performances, and vibrant street food markets.
8. Greenwich and the Royal Observatory :
Embark on a journey to Greenwich, a historic neighborhood and home to the Royal Observatory. Stand on the Prime Meridian Line, where the world’s time zones are measured, and enjoy panoramic views of London from Greenwich Park. Explore the fascinating exhibits at the Royal Observatory and delve into the maritime history of the area.
London’s vibrant city life beckons travelers with its diverse neighborhoods, iconic landmarks, and cultural experiences. From the historic grandeur of Buckingham Palace to the trendy markets of Camden Town and Notting Hill, this dynamic capital city offers something for everyone. Immerse yourself in the energy of London, explore its vibrant streets, and create lasting memories as you uncover the countless treasures this captivating city has to offer.

domain: geography


text:
Ngự Bình House
"Ngu Binh” House
Vietnam’s old poetry is the theme of ‘Ngu Binh’ House.
The House is a tribute to Ho Xuan Huong, one of Vietnam’s greatest classical poets.
Poems and paintings adorn the one-bedroom House following the Imperial style of the Nguyen Dynasty.
More about “Ngu Binh”
Núi Ngự Bình is a mountain close to Huế, Nui Ngu Binh is also known as the ‘Royal Screen’.
Ngu Binh Mountain is also known as Ngu Mountain or Hon Mo or Bang Mountain.
At a height of 103 meters, Ngu Binh is located approximately 4 kilometers south of the city of Hue. Two sides of this mountain have two smaller hills known as Ta Bat Son and Huu Bat Son, where the Nguyen Royal Dynasty decided to place the Hue Palace.


text:
Meaning – the Ocean, the sea and the wave in Sanskrit language. This concept is meant for leisure and business travelers who are looking for simple but yet cozy place to replace their “home” while they are traveling. An atmosphere of cool, calm but still give you the feeling of warm and friendliness around you. In the ambiance itself and the most important is the warm of the intire staff.
5th Floor, Suite A-537, Rasuna Epicentrum, Jl. HR. Rasuna Said
Jakarta , Indonesia


Ukraine-flagged vessel carrying 65 migrants intercepted – media
A Ukraine-flagged vessel with 65 migrants on board was intercepted early Tuesday morning by a Patra port authority patrol boat in the region of Kato Vasilikis in Aitoloacarnania, western Greece.
Three foreign nationals, aged 32, 30 and 37, were arrested on people smuggling charges, the website of Kathimerini English Edition, a daily newspaper published in Athens, reported.
Two more suspects were arrested – a 36-year-old Greek and a 37-year-old foreign national, who were the driver and co-driver of a truck that was waiting to collect the migrants on the shore.
As UNIAN reported earlier, Ukrainian Parliament's Commissioner for Human Rights Liudmyla Denisova said 112 Ukrainian citizens were imprisoned in Greece on charges of smuggling of migrants as of July 2018.


The Provincial and Demonstration Schools Branch, Ministry of Education, is seeking a licensed electrician to undertake the installation, maintenance, replacement, and repair of all electrical systems and components at the E.C. Drury School and Trillium Demonstration School, Milton Campus.
With both student lodging and day students, the schools include classrooms, recreational and dining facilities, and student lodges.
OPS Commitment to Diversity, Inclusion, Accessibility, and Anti-Racism:
We are committed to build a workforce that reflects the communities we serve and to promote a diverse, anti-racist, inclusive, accessible, merit-based, respectful and equitable workplace.
We invite all interested individuals to apply and encourage applications from people with disabilities, Indigenous, Black, and racialized individuals, as well as people from a diversity of ethnic and cultural origins, sexual orientations, gender identities and expressions.
Visit the OPS Anti-Racism Policy < https://www.ontario.ca/page/ontario-public-service-anti-racism-policy > and the OPS Diversity and Inclusion Blueprint < https://www.ontario.ca/page/ops-inclusion-diversity-blueprint > pages to learn more about the OPS commitment to advance racial equity, accessibility, diversity, and inclusion in the public service.
We offer employment accommodation across the recruitment process and all aspects of employment consistent with the requirements of Ontario’s Human Rights Code < http://www.ohrc.on.ca/en/ontario-human-rights-code >. Refer to the application instructions below if you require a disability-related accommodation.
What can I expect to do in this role?
- install and maintain various electrical devices, appliances, machines and equipment
- check and repair swimming pool lighting and filtering equipment
- repair and replace electric cables, transformers, and mercury vapour ballast for street lighting
- perform preventative maintenance on all equipment
- perform record-keeping of materials used, repairs, inspections and construction
How do I qualify?
- You have completed an apprenticeship in the electrical trade, and are recognized in Ontario as an Electrician 309A or equivalent.
You have knowledge of:
- equipment and tools used in the electrical trade
- relevant legislation, municipal by-laws and codes, provincial building codes, Lockout/Tag-out procedures, confined space entry, and working at heights in order to work safely
- blueprints, schematics and drawings to ensure the proper layout of installations such as switches and conduits
Other essential skills:
- verbal communication skills to provide instructions, discuss requests for new installations or extensive repairs, and explain technical matters in easily understood terms
- written communication skills to prepare and maintain logs, and prepare plans, sketches and cost estimates
- problem-solving skills to find defects in electrical, mechanical and electronic systems and to decide/recommend fixes and repairs
Salary Range: $28.01 – $30.42 Per Hour
- 1 Temporary, duration up to 12 months (with the possibility of extension), 255 Ontario St S, Milton, Central Region, Enhanced – Vulnerable Services Sector Screening Requirement
- In accordance with the Ontario Public Service (OPS), Employment Screening Checks Policy (ESCP), the top candidate(s) may be required to undergo a security screening check. Refer to the above to determine the screening checks that are required for this position.
Required security screening checks along with your written consent, will be sent to the Transition and Security Office (TSO), Talent Development Branch, Talent and Leadership Division to evaluate the results. If applicable, the TSO, with your written consent, will request and obtain any additional employment screening checks that were not obtained directly by you.
A record under the Criminal Code and/or other federal offence record(s) does not automatically mean you will be ineligible for the position. The employment screening check(s) will only be reviewed and evaluated by the TSO for the purpose of making a security clearance decision. The details of an individual’s employment screening check(s) will be considered in specific relation to the duties and responsibilities of the position being filled. Employment screening check records will be maintained by the TSO and kept strictly confidential.
Please apply online, only, by Monday, October 3, 2022, by visiting www.ontario.ca/careers, and entering Job ID 185643 in the Job ID search field. Please follow the instructions to submit your application. Faxes are not being accepted at this time. Late applications will not be accepted.
If you require accommodation in order to participate in the recruitment process, please contact us at www.gojobs.gov.on.ca/ContactUs.aspx to provide your contact information. Recruitment Services staff will contact you within 48 hours. Only those applicants selected for an interview will be contacted.
The Ontario Public Service is an inclusive employer. Accommodation will be provided in accordance with Ontario’s Human Rights Code.


text:
With its stock down 8.6% over the past three months, it is easy to disregard Globant (NYSE:GLOB). However, the company's fundamentals look pretty decent, and long-term financials are usually aligned with future market price movements. In this article, we decided to focus on Globant's ROE.
ROE or return on equity is a useful tool to assess how effectively a company can generate returns on the investment it received from its shareholders. Simply put, it is used to assess the profitability of a company in relation to its equity capital.
How Is ROE Calculated?
ROE can be calculated by using the formula:
Return on Equity = Net Profit (from continuing operations) ÷ Shareholders' Equity
So, based on the above formula, the ROE for Globant is:
6.2% = US$54m ÷ US$880m (Based on the trailing twelve months to December 2020).
The 'return' is the income the business earned over the last year. That means that for every $1 worth of shareholders' equity, the company generated $0.06 in profit.
What Is The Relationship Between ROE And Earnings Growth?
We have already established that ROE serves as an efficient profit-generating gauge for a company's future earnings. Depending on how much of these profits the company reinvests or "retains", and how effectively it does so, we are then able to assess a company’s earnings growth potential. Generally speaking, other things being equal, firms with a high return on equity and profit retention, have a higher growth rate than firms that don’t share these attributes.
A Side By Side comparison of Globant's Earnings Growth And 6.2% ROE
At first glance, Globant's ROE doesn't look very promising. A quick further study shows that the company's ROE doesn't compare favorably to the industry average of 15% either. Globant was still able to see a decent net income growth of 13% over the past five years. We reckon that there could be other factors at play here. Such as - high earnings retention or an efficient management in place.
As a next step, we compared Globant's net income growth with the industry and found that the company has a similar growth figure when compared with the industry average growth rate of 13% in the same period.
Earnings growth is an important metric to consider when valuing a stock. The investor should try to establish if the expected growth or decline in earnings, whichever the case may be, is priced in. By doing so, they will have an idea if the stock is headed into clear blue waters or if swampy waters await. Is Globant fairly valued compared to other companies? These 3 valuation measures might help you decide.
Is Globant Making Efficient Use Of Its Profits?
Overall, we feel that Globant certainly does have some positive factors to consider. With a high rate of reinvestment, albeit at a low ROE, the company has managed to see a considerable growth in its earnings. That being so, the latest analyst forecasts show that the company will continue to see an expansion in its earnings. To know more about the latest analysts predictions for the company, check out this visualization of analyst forecasts for the company.
When trading Globant or any other investment, use the platform considered by many to be the Professional's Gateway to the Worlds Market, Interactive Brokers. You get the lowest-cost* trading on stocks, options, futures, forex, bonds and funds worldwide from a single integrated account.
This article by Simply Wall St is general in nature. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned.
*Interactive Brokers Rated Lowest Cost Broker by StockBrokers.com Annual Online Review 2020
Have feedback on this article? Concerned about the content? Get in touch with us directly. Alternatively, email editorial-team (at) simplywallst.com.

domain: finance


text:
I've always loved everything about Apple. The products, the advertising, the culture... When they reached out for this special event I felt very humbled. I'll do my part to make the evening as entertaining as I can. I hope to see you all there.
We have a lot planned for the hour long discussion. The very cool and stylish executive editor of Gilt MAN Andy Comer will be moderating. We'll play some videos, talk film and style, and hopefully I'll get to meet some of you. The official after party is at my favorite Friday night spot The Jane Hotel. Big thanks to Apple and all of you. I have a feeling it's going to be a very special night!
An Intersection of Style with Filmmaker Jake Davis
December 10, 7:00 p.m. - 8:00 p.m.

domain: entertainment


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GOT A TIP?
WATCH ET ON TV
Stars' Most Regrettable Movie Roles
Nicki Minaj Responds to Her Butt Critics...
Is This Charlize Theron's Engagement Ring?
Inside the Bloody Brawl at Paris Hilton's
How Those 'Fifty Shades' Sex Scenes Were...
SHARE THIS GALLERY
REKS - 'Revolution Cocktail'
July 02, 2013
Rapper REKS is releasing his latest album Revolution Cocktail today. For more on REKS, go to rekshiphop.com.
ALSO IN THIS GALLERY:

domain: celebrity


Hearing continued for sex sting suspect
MARSHALL — A Monday hearing for a Lynd man charged in connection with a prostitution sting in Springfield was continued until later this month, Brown County court records said.
Lawrence Depyper, 70, appeared in Brown County District Court Monday on charges of agreeing to hire a person under 18 for prostitution. A complaint alleges Depyper called and texted an undercover agent posing as a 16-year-old girl and was arrested in August after arriving at a designated location and being invited inside.
Court minutes said Depyper represented himself at the hearing. Depyper had applied for a public defender and had been denied. Depyper told the court he had received $5,000 and $10,000 quotes for attorneys but couldn’t afford to pay that much, court minutes said.
After discussion of Depyper’s income, the court said an attorney would be appointed for Depyper. However, he would be required to pay some costs, court minutes said.
Depyper said he wanted to contest the evidence in his case, court minutes said. The hearing was continued until Oct. 31.
Depyper was one of eight men arrested in connection with the sting operation. A second area man, Paul Lund, Jr., of Cottonwood, was also charged with agreeing to hire a person under 18 for prostitution. A criminal complaint alleges Lund responded to an online advertisement posted by law enforcement, and arrived at an undercover location at a residence in Brown County. Lund’s next hearing in Brown County District Court is scheduled for Nov. 16.


text:
FRIDAY, Feb. 10 (HealthDay News) — Many gay men who regularly have risky sex would be willing to ask partners to use a new, rapid-result HIV test, a new study shows.
HIV is the virus that causes AIDS.
The tests, which use a mouth swab and detect HIV antibodies in less than 20 minutes, are currently used in testing clinics across the United States. The U.S. Food and Drug Administration approval of the tests for public use is pending, according to the researchers at the HIV Center at Columbia Psychiatry and the New York State Psychiatric Institute.
The researchers interviewed 57 gay and bisexual men, aged 18 and older, who said they had multiple male partners and rarely or never used condoms. Most of the men said they liked the idea of using the test kits to screen sexual partners.
The researchers also found that most of the men said they would likely ask partners to take an HIV test and might consider safe sex measures if the partner’s response raised doubts about his HIV status.
The study was slated for online publication in February in the Journal of Sex Research.
The tests do not detect the initial, acute stage of HIV infection that lasts for a few weeks, but “for men who are already having a high level of unprotected intercourse with multiple partners, access to a rapid HIV test that can be performed at home may prove to be a valuable harm-reduction tool,” principal investigator Alex Carballo-Dieguez, a clinical psychologist, said in a Columbia news release.
The researchers noted that an HIV home test could also protect heterosexual people who have risky sex.

domain: medical


text:
Swedish non-profit Talita has created a new mod for GTA 5 to highlight real-life issues of sex trafficking.
The organisation helps women out of prostitution and trafficking for sexual purposes and, through this mod, aims to raise awareness of these issues among young men – an audience key to shifting attitudes.
The mod, titled Mission Talita, includes four playable missions based on the true stories of four women the Talita organisation has helped between 2017 and 2023.
These missions take place in the streets of Los Santos, but flips the usual narrative of the game by sending players off to help women out of prostitution.
The GTA series is renowned for its misogynistic attitudes towards women in general, but specifically in-game sex workers. As the mod’s FAQ page reads: “What started out as a gangster game has now evolved into a world where people – particularly young men – hang out, take on different roles, and shape the storyline. However, it’s also a place where young men can buy virtual sex, every day. And in the game, the non-playable prostitute characters’ fate is set. They can almost only be exploited, abused, or murdered.
“Given that GTA might be many young men’s first exposure to victims of sex trafficking and prostitution, the risk is imminent that the game will affect their perception and attitudes toward prostitution in a harmful way.”
Mission Talita has been created by modder FelixTheBlackCat, with support from Vxruz_Danz. In addition, the mod includes an exclusive radio channel featuring music from Swedish House Mafia and other artists, as well as facts about Talita’s work.
The launch of the mod “goes to show our continued dedication to finding new ways of bringing visibility to the severe situations that far too many women all around the world face daily,” said Anna Sander, co-founder of Talita.
“With GTA being one of the world’s most played and streamed games, the launch of Mission Talita acts as a trojan horse that allows us to come into contact with an audience whose help we need to create meaningful and long lasting change.”
The mod uses the word “prostitute” rather than “victims of prostitution” or “women in prostitution” as it’s a word commonly used throughout GTA 5 and Talita wanted to stay true to that.
The FAQ also details why the women in the mod are portrayed as victims. “Our mission is to support and assist women exploited in prostitution and trafficking for sexual purposes and help them into a new life on their terms,” it reads. “Many argue that prostitution can be voluntary, but after meeting and talking with women in prostitution for 25 years, our experience is that an overwhelming majority come from poverty or carry early sexual traumas. These are strong push factors into prostitution.”
The mod is available to download on the Talita website. A copy of GTA 5 is required.
The GTA series is notorious for its depictions of sex and violence. One example is the inaccessible Hot Coffee sex minigame from GTA: San Andreas, later enabled through PC mods, which was discovered in the code of the recent GTA: The Trilogy – The Definitive Edition.
GTA 6 is set for release in 2025 and will feature a female protagonist. It’s unclear if prostitution will be included.

domain: news


US 20020072680 A1
An intra-aortic balloon catheter having a fiberoptic pressure sensor embedded in the tip.
1. An balloon catheter comprising a balloon membrane, a tube, a tip, and a stylet, a distal end of the tube is connected to a proximal end of the balloon membrane, the tip is connected to a distal end of the balloon membrane, a distal end of the stylet is connected to the tip, a proximal end of the stylet is connected to a distal end of the tube, the stylet being more flexible towards the distal end than the proximal end.
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 This application is a continuation-in-part of application Ser. No. 09/734,755, filed on Dec. 12, 2000, herein incorporated by reference in its entirety.
 1. Field of the Invention
 The invention relates to a catheter having enhanced pressure sensing capabilities. More particularly, the invention relates to single and dual lumen intra-aortic balloon catheters having a fiberoptic sensor connected to the catheter.
 2. Description of the Prior Art
 A key function of many catheters is that of continuously monitoring blood pressure. In many cases, this monitoring must be performed with accurate measurement of high frequency components. For example, reliable detection of the dicrotic notch of the aortic blood pressure waveform typically requires a pressure signal having a bandwidth of 15Hz or better. Detection of the dicrotic notch is generally used for the inflation/deflation timing of an intra-aortic balloon (“IAB”) catheter.
 Conventional invasive pressure monitoring is performed with low-cost fluid-filled transducers. A typical disposable monitoring kit, inclusive of all tubing, a continuous flush device, and a pre-calibrated transducer is very affordable. Unfortunately, these systems have several drawbacks. One major drawback is that bubbles or clots in the monitoring lines can reduce the frequency response of the system to a level below 15 Hz, creating an “overdamped” condition. In other cases, the characteristics of the catheter and tubing can result in “ringing”, which is associated with an underdamped condition. Furthermore, fluid-filled catheters can suffer from “catheter whip” (motion artifact), which is manifested as one or more high frequency deflections in the pressure signal. These problems can degrade the usefulness of the signal in applications such as intra-aortic balloon pumping (IABP). In particular, it is difficult, if not impossible, to automatically provide optimal timing of IABP using a pressure signal with a frequency response below 15 Hz, or using signals with ringing or whip artifacts that mimic the physiologic dicrotic notch.
 Another disadvantage of the traditional fluid-filled transducer is that it requires the use of an inner guidewire tube. Traditionally, IAB catheters have two lumens in the catheter: a gas shuttle lumen and an inner guidewire lumen. The gas shuttle lumen has to be large enough to allow the gas to shuttle back and forth without undue restriction to ensure speedy inflation and deflation of the IAB membrane. In order to make the catheter smaller it is desirable to remove the inner guidewire lumen or tube, thus requiring an alternate means for measuring arterial pressure.
 Another means for monitoring blood pressure is to use a micromanometer, such as marketed by companies such as Millar, Endosonics, and Radi. See U.S. Pat. Nos. 5,431,628 and 5,902,248, herein incorporated by reference. These devices can have excellent frequency responses, with system bandwidths greater that 200 Hz. They are not subject to the negative effects of bubbles and catheter whip, and retain good performance even in the presence of small blood clots. Unfortunately, they are very expensive, prone to signal drift, and can suffer from electrical interference. A common source of electrical interference in the setting of IABP therapy is the use of electrosurgery. In this situation, it is desirable to maintain a reliable pressure signal with which to trigger the balloon, as the ECG signal which normally triggers IABP operation becomes completely unreliable. Conventional fluid-filled transducer systems are relatively immune from this type of interference. Attempts have been made to use micromanometers for IABP timing, see U.S. Pat. Nos. 3,585,983 and 4,733,652, herein incorporated by reference. These attempts proved to be unreliable, as the device may be damaged during insertion and is also prone to signal drift. To address the drift issue, U.S. Pat. No. 5,158,529, herein incorporated by reference, discloses a method for rezeroing the micromanometer by using the pressure from a partially filled balloon as it rests in the aorta. However, this method requires momentary interruption of IABP, which may be harmful to the critically ill patient.
 While standard IAB catheters incorporating a fluid-filled transducer pressure measurement system or IAB catheters incorporating micromanometers may be suitable for the particular purpose employed, or for general use, they would not be as suitable for the purposes of the present invention as disclosed hereafter.
 Accordingly, there is a need for a reliable and affordable pressure monitoring approach that has high bandwidth pressure sensing, low signal drift, and freedom from electrosurgical interference. There is also a need to incorporate this technology into intra-aortic balloon catheters having small cross sectional profiles.
 The invention is an IAB catheter system, with either a double or single lumen, having enhanced blood pressure sensing capability. The IAB catheter has a fiberoptic sensor built into the tip of the IAB or connected to another part of the catheter.
 Fiberoptic sensors have the advantage of being immune to electrical interference, and have the potential to be lower in cost than electronic micromanometers.
 To the accomplishment of the above and related objects the invention may be embodied in the form illustrated in the accompanying drawings. Attention is called to the fact, however, that the drawings are illustrative only. Variations are contemplated as being part of the invention, limited only by the scope of the claims.
 In the drawings, like elements are depicted by like reference numerals. The drawings are briefly described as follows.
FIG. 1 is a longitudinal cross sectional view of a distal end of a coaxial IAB catheter having a fiberoptic sensor in the tip.
FIG. 1A is a perspective view of distal end of inner tube 58, shown independent of catheter 10, with pressure sensing line 24 connected to an outer surface of inner tube 58.
FIG. 1B is a perspective view of a distal end of inner tube 58, shown independent of catheter 10, with pressure sensing line sandwiched between an outer surface of inner tube 58 and an outer layer.
FIG. 1C is a perspective view of a distal end of inner tube 58, shown independent of catheter 10, with pressure sensing line 24 embedded in the wall of inner tube 58.
FIG. 2 is a longitudinal cross sectional view of a distal end of a co-lumen IAB catheter having a fiberoptic sensor in the tip.
FIG. 2A is a transverse cross sectional view of the co-lumen IAB catheter in FIG. 2 taken along lines 2A-2A.
FIG. 3A is a longitudinal cross sectional view of the tip having an embedded fiberoptic sensor in a first configuration.
FIG. 3B is a longitudinal cross sectional view of the tip having an embedded fiberoptic sensor in a second configuration.
FIG. 3C is a longitudinal cross sectional view of the tip having an embedded fiberoptic sensor in a third configuration.
FIG. 3D is a longitudinal cross sectional view of the tip having an embedded fiberoptic sensor in a fourth configuration.
FIG. 4 is a longitudinal cross sectional view of a single lumen IAB catheter having a fiber optic sensor in the tip.
FIG. 5A is a perspective view of the single lumen catheter of FIG. 2 having a monorail tip and a guide wire passing through it.
FIG. 5B is a perspective view of the single lumen catheter of FIG. 2 having a monorail tip and a guide wire passing through it as well as the balloon membrane.
FIG. 6 is a perspective view of a distal end of the catheter connected to the stylet via a catheter tongue extension.
FIG. 7A is a perspective view of a transparent wire reinforced catheter having a straight exposed distal portion forming a stylet.
FIG. 7B is a perspective view of a transparent wire reinforced catheter having an exposed straight distal wire portion connected to a tube to form a stylet.
FIG. 7C is a perspective view of a transparent wire reinforced catheter having an exposed helical distal wire portion connected to a tube to form a stylet.
FIG. 1 illustrates a longitudinal cross section of a distal portion of a dual lumen intra-aortic balloon (“IAB”) catheter 10 comprising an outer tube 56, an inner tube 58, a tip 20, and a balloon membrane 30 connected on one end to the outer tube 56 and on the opposite end to the tip 20. Tip 20 defines a tip lumen 21. Inner tube 58 is disposed within the outer tube 56 and is connected to the tip 20 at its distal end. Inner tube 58 defines an inner lumen 60 and outer tube 56 defines an outer lumen 28. Outer lumen 28 is used for shuttling helium or another appropriate working gas or fluid for inflation and deflation of the balloon membrane 30. Outer tube 56 may be coil or braid reinforced and made from polyurethane or polyimide. Inner tube 58 may be made from polyimide or an alloy with shape memory and superelastic properties commonly referred to as Ni—Ti, NITINOL™, and other industry names. Inner tube 58 may be connected to an inner surface of the outer tube 56 at one or more points to enhance pushability, stability, pumping speed, and pressure fidelity. Furthermore, inner tube 58 may be made from two or more tubes joined end-to-end, as disclosed in U.S. Pat. No. 6,024,693, herein incorporated by reference in its entirety, or may have an inner tube having a variable diameter, as disclosed in U.S. patent application Ser. No. 09/764,831, filed on Jan. 17, 2001, herein incorporated by reference. Fiber optic sensor 22 is embedded in or attached to the tip 20 and preferably has a diameter less than or equal to 0.03 inches (0.762 mm). A forward looking end of the fiberoptic sensor 22 faces chamber 23. Pressure sensing line 24 may be affixed to inner tube 58 and connects fiber optic sensor 22 to an optoelectronic interface (not shown) via an industry-standard “SC” connector (not shown). Pressure sensing line 24 preferably is made of glass, but may be made of plastic or another material, and preferably has a diameter less than or equal to 0.006 inches (0.152 mm). Note that fiberoptic sensor 22 may be positioned in alternate locations along IAB catheter 10 as well as on a distal tip of an independent catheter that can be disposed within inner lumen 58.
 FIGS 1A-1C illustrate perspective views of a distal end of inner tube 58 with pressure sensing line 24 connected to inner tube 58 in various configurations. In FIG. 1A, pressure sensing line 24, is connected to an outer surface of inner tube 58. In FIG. 1B, pressure sensing line 24 is disposed between inner tube 58 and a thin walled tube 64, which preferably is heat shrinkable. Heat shrinkable tubing with a wall thickness of less than or equal to 0.001 inches (0.0254 mm) is available from Advanced Polymers, Inc., Salem, N.H. In FIG 1C, pressure sensing line 24 is embedded in the wall of inner tube 58. Note that although pressure sensing line 24 is shown running along a longitudinal axis of inner tube 58 it may also be wound helically.
FIG. 2 illustrates a distal portion of another embodiment of the IAB catheter 10, comprising a balloon membrane 30, a tip 20, a co-lumen tube 56, an inner lumen extension tube 66, and a fiberoptic sensor 22. Detailed structure of a co-lumen IAB is disclosed in U.S. Pat. No. 6,024,693 and U.S. patent application Ser. No. 09/412,718, filed on Oct. 5, 1999, both herein incorporated by reference. Tip 20 is connected to a distal end of the balloon membrane 30 and to a distal end of the inner lumen extension tube 66. Tip 20 defines a tip lumen 21. A distal end of the co-lumen tube 56 is connected to a proximal end of the balloon membrane 30 and to a proximal end of the inner lumen extension tube 66. The co-lumen tube 56 may be coil or braid reinforced and made from polyurethane or polyimide. The preferred material for inner lumen extension tube 66 is an alloy with shape memory and superelastic properties commonly referred to as Ni—Ti, NITINOL™, and other industry names. Inner lumen extension tube 66 may also be made from polyimide. The fiberoptic sensor 22 is attached to tip 20 and pressure sensing line 24 which communicates signals generated by the fiberoptic sensor 22 to an optoelectronic interface (not shown). The pressure sensing line 24 may be connected to the inner lumen extension tube 66 and co-lumen tube 56 in any of the ways pressure sensing line 24 is connected to the inner tube 58, illustrated in FIGS 1A-1C. Furthermore, the pressure sensing line may be embedded in the outer tube 56 as illustrated in FIG. 2A.
FIG. 2A illustrates a transverse cross section of outer tube 56, taken along line 2A-2A illustrated in FIG. 2, with pressure sensing line 24 embedded in the wall. Outer tube 56 defines two distinct lumens, inner lumen 60 and outer lumen 28. Outer lumen 28 is used for shuttling helium or another appropriate fluid or gas for inflation and deflation of balloon membrane 30. Note that pressure sensing line 24 may be embedded at a different location in outer tube 56, may be connected to a surface of outer tube 56, or may freely reside in outer lumen 28. Note also that the fiberoptic sensor 22 may be positioned in alternate locations along IAB catheter 10 as well as on a distal tip of an independent catheter that can be disposed within the inner lumen 60.
 FIGS. 3A-3D illustrate alternate configurations for tip 20 incorporating a forward looking fiber optic sensor 22. In FIG. 3A and FIG. 3B longitudinal cross sections of tip 20 are shown independent of the rest of catheter 10 for clarity. In FIG. 3A fiber optic sensor is embedded in tip 20 parallel to the longitudinal axis of tip 20 labeled A. Fiber optic sensor 22 has an approximate outer diameter of 0.0025 inches (0.0635 mm) and has a pressure sensing surface or diaphragm 80 on a distal end which is exposed to protective pocket 82. Diaphragm 80 may be made from silicone approximately 6 microns thick and is protected from physical damage and blood contact by protective pocket 82, which may contain a gel, fluid, gas, elastomer, or any other flexible protective material. Diaphragm 80 may project into the pocket or may be flush with the protective pocket 82 wall. Membrane 84 prevents leakage of gel or protective pocket 82. Pressure sensing line 24 comprises a fiberoptic fiber having an outer diameter of approximately 0.006 inches (0.152 mm). In FIG. 3B (and also FIGS. 1 and 3) the gel or protective pocket 82 is shifted proximally. In FIG. 3C a distal portion of balloon membrane 30 is used to seal protective pocket 82. In FIG. 3D protective pocket 82 opens into inner lumen 60. Membrane 84 prevents leakage of gel out of protective pocket 82. In this location fiberoptic sensor 22 is exposed to arterial pressure via tip lumen 21 and is less likely to be damaged upon insertion and placement of IAB catheter 10. Note that although forward looking fiber optic pressure sensors are illustrated, use of side looking sensors is anticipated as well.
 In addition to sensing blood pressure, the fiberoptic sensor 22 can be used to measure other important physiologic variables, such as, but not limited to temperature (as in the Luna Innovations sensor noted below), pCO2, pO2, pH, oxygen saturation, lactate, CPK, anesthetic agent concentration, various biological compounds, electrolytes, and nitric oxide. Blood pressure, as well as at least some of these variables, could be measured using either extrinsic or intrinsic fiberoptic sensors. Extrinsic sensors use the fiberoptic fiber to communicate information from a separate structure which is attached to the fiber. Intrinsic sensors sense information as a result of physical changes of the fiber itself. Intrinsic sensors have a particular advantage of being extremely small, rugged, and low in cost.
 As indicated above the pressure sensing line 24 terminates in an optoelectronic interface which provides a light source, light detector, optical components (such as a lens, splitter, and interferometer), power supply, and signal processing means. This optoelectronic interface is known in the art and can be connected to or integrated with another electronic device, such as a monitor or intra-aortic balloon pump. Light originating from the interface travels down the fiberoptic fiber, i.e. the pressure sensing line 24, by the well-known principal of total internal reflection to the sensing element. The sensing element incorporates pressure responsive means which modifies the character of the light as a function of pressure. The modified light is in turn reflected back through the fiber to the interface. The optical components, light detector, and signal processing elements of the interface work together to produce an electrical output that characterizes the pressure at the sensor. This output is translated into a displayed pressure waveform or digital pressure display by the IABP or monitor.
 Fiberoptic pressure monitoring sensors and optoelectronic interfaces suitable for this application are manufactured by several companies, including FISO Technologies Inc. (Quebec, Canada) and Luna Innovations (Blacksburg, Va.). FISO utilizes a white light interferometric approach, as described in U.S. Pat. Nos. 5,202,939 and 5,392,117, herein incorporated by reference in their entirety. Luna Innovations uses a laser light source in an approach similar to that described in U.S. Pat. No. 5,301,001, herein incorporated by reference in its entirety.
 There are a variety of possible configurations for the fiberoptic sensor itself. One type would employ a deformable diaphragm separated from the end of one or more fiberoptic fibers by a chamber. The chamber may be filled with air and vented to atmosphere to eliminate temperature-induced pressure changes within the chamber (these would be associated with signal drift). A disadvantage of this design in an IAB catheter is that an air-venting tube is required which occupies a portion of the cross-sectional area of the catheter. This tube reduces the potential to produce the catheter in a small size with acceptable performance.
 A more desirable approach to a fiberoptic pressure sensor for a small catheter is to utilize a design without a vent tube (as illustrated in FIGS. 1, 2, and 3A-3D). Such a sensor can be produced by positioning the sensor diaphragm over a chamber with a vacuum (as currently practiced by FISO). With this approach, a sensor can be constructed which has little temperature-induced drift, assuming that the materials which are used to build the diaphragm and chamber have small coefficients of thermal expansion (ceramics, glass, and silicon are good choices). This approach makes the device an absolute pressure sensor, which requires a separate barometric pressure sensor to convert absolute pressures to gauge pressures. In IABP applications, such a barometric pressure sensor could be built into the pump. U.S. Pat. No. 5,158,529, herein incorporated by reference in its entirety, teaches another possible means for assuring the accuracy of gauge pressure values as indicated by a sensor in the IAB catheter; this approach compares the blood pressure values indicated by the catheter sensor with pressure values in the gas within a partially-filled catheter and pump, and adjusts the sensor-indicated pressure to agree with the gas pressure.
 Another approach to constructing a non-vented pressure sensor is to trap a gas in the chamber beneath the diaphragm and to monitor its temperature (as currently practiced by Luna Innovations). In this case, knowledge of the gas temperature within the chamber allows for correction of temperature-induced pressure changes. Ideally, if a gas is to occupy the chamber, it is dry and inert. It is possible that appropriate selection of the bias gas would improve linearization of the sensor or change its dynamic range.
FIG. 4 illustrates a single lumen IAB catheter 10, comprising balloon membrane 30, a J-shaped tip 20, a stylet 90, a gas lumen insert 98, and a fiberoptic sensor 22. Tip 20 is connected to a distal end of balloon membrane 30 and preferably has an outer diameter of approximately 6 millimeters. Balloon membrane 30 preferably has a single wall thickness of approximately 0.0023 inches (0.0584 mm) and defines a volume of 40 cubic centimeters. Fitting 92 is connected to a proximal end of catheter 10. Tube 94 connects connector 96 to fitting 92. Fiber optic sensor 22 is embedded in or attached to tip 20 and preferably has a diameter less than or equal to 0.03 inches (0.762 mm). A forward looking end of fiberoptic sensor 22 faces chamber 23. Pressure sensing line 24 may be free-floating within a lumen in catheter 10 or embedded in catheter 10 similar to the connection configurations illustrated in FIGS 1A-1C in connection with inner tube 58. Pressure sensing line 24 connects fiber optic sensor 22 to an optoelectronic interface (not shown) via an industry-standard “SC” connector 96A.
 In addition to connector 96A, connector hub 97 may also include data input/out connector 96B for data input and output beneficial to optimization of the device and/or data logging onto a data storage device incorporated into connector hub 97 (not shown). Incorporation of connector 96B results in a fully integrated pneumatic, electrical, and electro-optical connector hub.
 A distal end of stylet 90 is connected to tip 20 inside tip lumen 25. A proximal end of stylet 90 is connected to an inner surface of a reinforcement ring or skirt 91 which in turn is connected to an inner surface of a distal end of catheter 10. Skirt 91 is preferably made from stainless steel but can also be made from Nitinol or another appropriate stiff material.
 Pressure sensing line 24 preferably is made of glass, but may be made of plastic or another material, and preferably has a diameter less than or equal to 0.006 inches (0.152 mm). Pressure sensing line 24 is connected to an outer surface of stylet 90 but may also be connected in any of the ways illustrated in FIGS. 1A-1C. If stylet 90 is made from a tube, pressure sensing line 24 may pass through the tube. Pressure sensing line 24 is disposed within catheter 10 and passes through fitting 92, tube 94, and terminating in connector 96.
 Note that all the details regarding pressure sensor 22 detailed above for the coaxial and co-lumen catheters apply equally to the single lumen embodiment. Note further that pressure sensor 22 for the single lumen embodiment is optional. Pressure information may be obtained through other means, such as but not limited to, pressure lines placed elsewhere on the patient's body, e.g. radial line. Another alternative would be to employ an alternative timing signal, such as blood flow or heart sounds.
 Catheter 10 is preferably made from a spiral wire reinforced polyurethane, polyimide, or Pebax (Pebax is a trademark of Elf Atochem Inc. of Birdsboro, Pa.) material. The outer diameter of catheter 10 is preferably 0.085 inches (2.16 mm) and the inner diameter is preferably 0.073 inches (1.85 mm). Note that the preferred dimensions translate to approximately a 6 Fr. catheter (a one millimeter diameter is approximately 3 Fr.) which is a significant size reduction compared to current dual lumen catheters on the market the smallest of which is an 8 Fr. catheter, sold by Datascope Corp.
 The lack of a guidewire lumen allows for a significant reduction in the outer diameter of catheter 10, roughly 2 Fr. Given the fact that catheter 10 no longer has a guidewire lumen the catheter design must allow for insertion without a guidewire. This is accomplished through the incorporation of stylet 90, removable gas lumen insert 98, and J-shaped tip 20 into the design of catheter 10.
 Removable gas lumen insert 98 is removably disposed within catheter 10 and connects to fitting 92 via a connector 106. As detailed in U.S. patent application Ser. No. 09/813,905, filed on Mar. 21, 2001, herein incorporated by reference in its entirety, catheter 10 is inserted into a patient with gas lumen insert 98 disposed within catheter 10 to enhance the stiffness of catheter 10, and thus, facilitate insertion. After insertion gas lumen insert 98 is removed, vacating lumen 28, and allowing for shuttling of gas through lumen 28 for inflation and deflation of balloon membrane 30. Gas lumen insert 98 is preferably made from stainless steel but may also be made from Nitinol or another appropriate stiff material.
 Stylet 90 is preferably made from solid stainless steel or Nitinol wire having a 0.020 inch (0.508 mm) diameter tapering down at point T towards tip 20 to a 0.010 inch (0.254 mm) diameter. Stylet 90 may also be made from a tube and from any other material having the appropriate stiffness necessary for IAB insertion and therapy. Alternate means for incorporating stylet 90 into IAB catheter 10 are disclosed in U.S. Pat. No. 5,716,373, issued Wolvek et al., herein incorporated by reference in its entirety. The graduated diameter, and thus, stiffness of stylet 90 allows IAB catheter 10 to mimic the ability of a typical guidewire to pass through tortuous arteries. Note that location of the transition point T may vary, as well as the total variation of diameter and the degree of transition, so long as the distal end of the stylet is less stiff than the proximal end. Furthermore, to accomplish the transition in stiffness two tubes having varying diameters or different material properties may be connected end-to-end. Alternatively, a single tube having varying material properties, i.e. stiffness, along its length may be used.
 As a first step in the insertion process, a standard guidewire is placed into a patient's blood vessel. If a sheath is to be used, a sheath-dilator assembly is then advanced over the guidewire in a standard manner. To maximize the ease of insertion a long sheath, approximately 11 inches (279 mm) to 15 inches (381 mm), may be used. The dilator and guide wire are then removed and the IAB catheter 10 is advanced into the sheath until it reaches the desired position in the aorta. Prior to the initiation of therapy gas lumen insert 98 is unlocked from connector 106 and pulled out from catheter 10. After removal of stylet 90 the port through which it was positioned in fitting 92 is sealed by a means (not shown) such as a cap, a self-sealing valve, or a manually sealable valve.
 In an alternative embodiment, as illustrated in FIGS. 5A and 5B, catheter 10 may have a monorail tip which allows for a sheathless insertion. FIG. 5A illustrates a perspective view of catheter 10 with a guide wire 100 disposed within a lumen 102 in monorail tip 104. Stylet 90 is revealed using shadow lines. Balloon membrane 30 is wrapped around stylet 90 to minimize the cross section profile of the system for insertion. Preferably the outer diameter of the wrapped balloon membrane 30 is equal to or less than an outer diameter of catheter 10, as disclosed in U.S. patent application Ser. No. 09/210,922, filed on Dec. 14, 1998, herein incorporated by reference in its entirety. Guidewire 100 enters tip 104 through a distal opening 103 and exits through a proximal opening. This is in contrast to the embodiment illustrated in FIG. 5B where guidewire 100 enters through distal opening 103 in tip 104 but then continues through balloon membrane 30 and finally exits through an opening in catheter 10 near the proximal end of balloon membrane 30.
 In the case of a sheathless insertion, guidewire 100 is first advanced into the aorta as described above and a proximal end of guidewire 100 is inserted through lumen 102 within tip 104. Flexible J-shaped tip 104 is straightened by guide wire 100. IAB catheter 10 is then advanced into the sheath until it reaches the desired position in the aorta. Next, guidewire 100 is removed, allowing tip 104 to recover its J-shape. Finally, gas lumen insert 98 is pulled out of catheter 10 and therapy can be initiated.
 An alternate approach to bonding sylet 90 to catheter 10 is illustrated in FIG. 6. Stylet 90 is fixed to a tongue 108 extending from a distal end of catheter 10 using any one of a variety of bonding methods, including but not limited to, a crimped sleeve, heat-shrink tubing, adhesive, or radio-frequency induced melt bonding. A proximal portion of stylet 90 may be roughened or contoured to optimize strength of the joint. With the use of reinforced tubing for catheter 10 several other unique attachment methods for stylet 90 are possible.
 With the use of reinforced tubing for catheter 10 several other unique attachment methods for stylet 90 are possible. FIG. 7A illustrates a perspective view of transparent catheter 10 having a wire reinforcement 110. A distal unwound portion 112 of wire reinforcement 110 serves as a stylet. If a distal portion of wire reinforcement 110 is not stiff enough it may be joined to a tube 114 or a secondary wire having the desired properties, including the transition in diameter and/or stiffness, as illustrated in FIG. 7B. Note that a proximal portion of tube 114 is optionally angled so as to control the stiffness of the wire/tube joint.
FIG. 7C illustrates a third method for joining stylet 90 to catheter 10. In this case, stylet 90 is fixed to a distal portion of exposed wire reinforcement 110. Optionally, there is an exposed portion of catheter 10 that is not joined to stylet 90. This un-joined exposed portion acts as a joint of specific flexibility for optimization of the stylet-to-catheter joint and allows for a better transition between the mechanical characteristics of stylet 90 and catheter 10.
 As many apparently widely different embodiments of the present invention can be made without departing from the spirit and scope thereof, it is to be understood that the invention is not limited to the specific embodiments thereof except as defined in the appended claims.


- BBC Studios delivers profit in its first year as a commercial subsidiary
- BBC Worldwide EBITDA up 42 per cent and returns to the BBC remain stable at £210m
- Results demonstrate a strong base for the newly integrated BBC Studios, which began trading on 3 April 2018
BBC Studios recently announced the 2017/2018 financial results for BBC Worldwide and BBC Studios, the BBC’s wholly-owned commercial subsidiaries which formed a single integrated group, BBC Studios, on 3 April 2018.
The results reveal that each commercial entity joined together to form a single commercial group from a strong financial base, with BBC Studios reporting headline sales of £432.0m and EBITDA of £7.2m in its first year of trading, and BBC Worldwide showing an increase in EBITDA to £118.3m, while sustaining cash returns to the BBC above £200m for a fourth successive year.
Tim Davie, CEO for BBC Studios, and formerly CEO of BBC Worldwide, during the financial year, said: “BBC Worldwide delivered a solid performance for 2017/2018 against a rapidly changing and an ever more competitive landscape. The results reflect strong delivery against our strategy; investing in premium British IP and an increased focus on customer management have led to another record year for content sales, while our productions, formats and branded services continue to extend their global footprint and find wider audiences.”
“BBC Worldwide entered the merger with BBC Studios from a strong position. Joining our world-class distribution capability with the UK’s most awarded production company was the most natural step to keep us both fit for the future. I am confident about the prospects of the new BBC Studios and what we can achieve together,” he added.
Mark Linsey, chief creative officer for BBC Studios, and formerly director of BBC Studios, during the 2017/2018 financial year, said: “It’s testament to the hard work and dedication of our hugely talented programme-makers and business teams that we have turned a profit in your first year of operating as a commercial entity. This year we received 200 nominations and over 80 awards for our content. Three of the top five British shows of 2017 were ours, proving that our programmes have made a huge impact on audiences. Not only that, we won new business from third-party broadcasters both here in the UK and around the world. We now look forward to consolidating and growing our success within the newly merged BBC Studios.”
||· Headline sales:
· EBITDA: £7.2m
|· Most awarded producer in the UK in 2017/2018 with more than 80 awards and 200 nominations
· Produced three of the UK’s top five most-watched programmes of 2017, including One Love Manchester, Strictly Come Dancing and Blue Planet II
· Blue Planet II, with a UK audience of 14m, was the most watched Natural History programme in 15 years
· Commissions secured beyond the BBC, including The Red List for Discovery, Fatberg Autopsy for Channel 4, Inside Hotel Chocolat for Channel 5 and Sex, Knives and Liposuction, Cherry Healey’s exploration of plastic surgery for UKTV, demonstrating a wider appetite for BBC Studios’ editorial offering
||· Headline sales down 2 per cent at £1,044.0m (2016/17: £1,059.9m)
· EBITDA up 42 per cent at £118.3m (2016/17: £83.5m)
· Cash returns of £209.9m to the BBC (2016/2017: £210.5m), over £200m for the fourth year running
· Free cash generation up 34 per cent at £121.4m (2016/17: £90.8m)
|· Global success for Blue Planet II from BBC Studios’ Natural History Unit: sold to 234 territories at year-end
· Record performance in Content Sales at £422.8m (2016/2017: £422.4m)
· Slight reduction in headline sales through factors such as the inter-group transfer of advertising sales, continuing decline in the DVD market and fewer US production hours on Dancing with the Stars
· Indie returns of £148.6m (2016/17: £146.4m), up 1.5 per cent, in addition to equity investment into two British indies, Sid Gentle Films Ltd and Various Artists Ltd, along with an increased shareholding in Clerkenwell Films
· Strong first year for US SVOD service BritBox, in partnership with ITV plc, hitting a quarter of a million subs milestone and launching in Canada by fiscal year end
· Memorandum of Understanding agreed with Shanghai Media Group Pictures to expand the Doctor Who brand in China
BBC Studios financial results
BBC Studios launched as a commercial subsidiary in April 2017, as part of a major change to the BBC’s content supply strategy. As a result, it ceased to have a guarantee of business from the BBC but gained the ability to pitch programming to other commissioners in the UK and internationally for the first time.
The business has achieved a successful first year of trading. BBC Studios produced over 2,000 hours of content in 2017/18, generating headline sales of £432.0m and EBITDA of £7.2m, supported by reductions in costs.
Content highlights and winning business
On-screen, BBC Studios content received widespread industry recognition with more than 80 awards and 200 nominations, making it the most awarded producer in the UK. Drama Three Girls and Natural History landmark Planet Earth II were particular highlights, winning 35 awards between them.
BBC Studios delivered many of the most-watched programmes of the year with One Love Manchester, the biggest series launch to date for Strictly Come Dancing, and EastEnders and Mrs Brown’s Boys topping viewing over the Christmas period.
The launch of Blue Planet II with an audience of 14m made it the biggest natural history programme in 15 years, and the resulting anti-plastics campaign demonstrated the power of television to make an impact on society.
Following its launch as a commercial business, BBC Studios’ strategy has been to develop a more balanced portfolio of business by continuing to deliver existing programmes to the highest creative standards and across multiple genres and specialisms, whilst investing in generating new intellectual property and diversifying its customer base.
A key challenge for the company has been the tendering of returning programmes: BBC Studios was successful in winning three of the four tenders, for Question of Sport, Holby City, and Doctors, as well as a majority of slots for Horizon. New business with the BBC this year has included daytime drama Shakespeare & Hathaway and a recommission for BBC Three comedy series This Country.
BBC Studios made good progress in securing commissions with other broadcasters, including Fatberg Autopsy for Channel 4, Inside Hotel Chocolat and The Bermuda Triangle for Channel 5, Sex, Knives and Liposuction for UKTV and The Red List for Discovery, all demonstrating a wider appetite for BBC Studios’ editorial offering.
BBC Worldwide financial results
BBC Worldwide delivered headline sales of £1,044.0m (2016/17: £1,059.9m), a reduction of 2 per cent from the prior year. The business achieved growth in BBC branded channels, acquired a majority stake in scripted indie Sid Gentle Films Ltd and matched the previous year record in Content Sales with the business again being the world’s largest distributor of UK content. Production and Formats grew in Global Markets, with a reduction in the Americas from fewer hours of Dancing with the Stars. This growth was offset by the inter-group transfer of advertising sales in order to align more closely with the rest of the Global News Limited business, continuing decline in the DVD market and the impact of contract renewals in UKTV.
EBITDA of £118.3m was 42 per cent higher than the prior year. This reflected a strong performance in Content Sales, cost efficiencies across Branded Services and overhead savings, which offset significant currency pressure and a decline in Consumer Products. Once adjusted for one-off specific items in the prior year, such as a change of amortisation profile, the closure of the Latin American channels business and BBC Store, alongside joint venture performance and foreign exchange, this represents a 16 per cent increase.
Free cash flow of £121.4m was 34 per cent higher than the prior year (2016/17: 90.8m). Once adjusted for one-off specific items alongside foreign exchange and joint venture performance, this represents a 41 per cent increase in owned and operated free cash flow.
The financial results reflect good delivery of BBC Worldwide’s transformation programme, with an increased focus on intellectual property (‘IP’) ownership; on high-value customers and markets; and on global franchise brands.
2017/2018 saw a sustained record performance in Content Sales at £422.8m (2016/17: £422.4m) with landmark natural history series Blue Planet II, the fifth and final series of BBC AMERICA commission Orphan Black, and Planet Earth II all selling to over 220 territories in the year.
BBC Worldwide invested £170.5m in content during 2017/2018, with direct funding for BBC commissioned content increasing by 7.5 per cent to £106.4m (2016/17: £99.0m), supporting on-screen programmes across the BBC’s channels.
Blue Planet II from BBC Studios’ Natural History Unit was the most widely sold programme of the year, selling to 234 territories by year-end. In the US, BBC America and the entire suite of AMC Network channels premiered episode one, which became the most watched advertising-supported nature episode in nearly eight years in the US, while Blue Planet II content amassed over 250m views on Chinese VOD platform Tencent between September 2017 and year-end.
International versions of popular British shows continue to attract large local audiences with the third series of Bake Off Brazil, Mao na Massa, becoming the highest rated cooking show on Brazilian television last year and the opening episode from the third series of Dancing Brasil garnering a best-ever 8.1m rating for free-to-air broadcaster RECORDTV. Elsewhere, a new partnership with Applause Entertainment in India will see local versions of Criminal Justice and The Office. In Korea, Munhwa Broadcasting Corporation (MBC) licensed the scripted format for Luther, with local adaptations of the hit BBC series Mistresses and Life on Mars airing on South Korean screens this spring/summer. In Russia, Star Media will produce a local version of Doctor Foster for broadcast on Russia 1 during 2018.
BBC Worldwide was voted the number one distributor by peers, for the second year running, through Broadcast in September 2017. BBC Worldwide was praised for the range and quality of its catalogue and recognised for its progress in transforming the content sales business to stay ahead of an increasingly challenging market.
International BBC-branded services performed strongly in the year, with BBC America posting a record 13th straight year of prime ratings growth, BBC First becoming the Netherlands’ most watched international channel since the start of 2018, and Sony BBC Earth (a joint venture channel with Sony Pictures) marking its first birthday by becoming the most watched infotainment channel in six Indian metros. BBC Earth’s linear channel footprint expanded across Greece and the Balkans.
BritBox, the subscription video on demand service partnership with ITV plc, had a strong first year in the US. It also launched into Canada in February 2018 and reached the milestone of over 250,000 subscribers collectively for the US and Canada by the fiscal year end. The service also announced its first original commission as a co-producer alongside ITV, The Bletchley Circle.
BBC Worldwide entered into several innovative global deals during 2017/18, including a Memorandum of Understanding (MOU) with Shanghai Media Group Pictures which will see an expansion of the Doctor Who brand in China. Partnerships with Foxtel, the ABC, Sky, and Fetch were cemented with new or continued deals in Australia and New Zealand. In the digital space, a partnership with Google Daydream saw the release of BBC Earth: Life in VR, an award-winning, immersive natural history experience which offers a unique perspective on the world’s oceans through the power of virtual reality.
Meanwhile, joint venture UKTV performed well, despite a soft advertising market and the impact of contract renewals. Shortly before year end, in March 2018, the shareholding of Scripps Networks Interactive Inc. in UKTV was purchased by Discovery Inc.
Supporting the Creative Industries
Relationships continued to be built across the independent sector, with total returns to indies through rights investment, royalties and profit shares up 1.5 per cent at £148.6m (2016/17: £146.4m) during the year. In addition to this, BBC Worldwide made new equity investments in two British independent drama production companies, Sid Gentle Films Ltd and Various Artists Ltd, and increased its shareholding in Clerkenwell Films, supporting British entrepreneurship and IP generation while enhancing the future of its own content supply. During the year BBC Worldwide sold its share of production incubator, Greenbird Media. BBC Worldwide also accounted for an important element of the UK’s £902m revenue generated from TV exports.
In November 2017, it was announced that BBC Worldwide would merge with BBC Studios to form a single integrated group, in line with industry norms, combining the BBC’s world-renowned television production arm, now a fully commercial subsidiary, with BBC Worldwide’s activities across production, channels, sales, and ancillaries. The merger, which completed on 3 April 2018, strengthens IP generation and enhances content supply, helping to secure the future of the BBC as a long-term creator and owner of the highest quality British content, for the benefit of its audiences at home and beyond.
 Including the benefit of one-off charges in the prior year
 Including production tax credits
 BBC Studios results relate to the subsidiary known as BBC Studios during the financial year, not the subsequent merged company of the same name
 PACT TV Export Report 2016-2017 published in June 2018


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KUALA LUMPUR – The high-end residential segment, particularly strata units, is heading towards a price correction this year after a rapid rise in prices driven by the now-banned Developer Interest Bearing Scheme (DIBS).
CBRE-WTW managing director Foo Gee Jen said prices of high-end stratified residential properties would see a 10% to 15% correction this year, while landed residential properties may see a correction of not more than 10%, if at all.
“You have to go back to the history of what happened two to three years ago. Whenever developers offer a project, a lot of DIBS and so forth were catered to stratified properties. For landed properties there were no issues in selling so there’s not so much mark-up in terms of pricing for landed properties but a lot of mark up for stratified properties,” Foo told reporters at the 2017 Asia Pacific Real Estate Market Outlook briefing yesterday.
Some of the units bought with DIBS and other forms of rebates are back in the market today, at prices that are much lower than the original selling prices two years ago, and Foo said this is particularly apparent in Johor Baru, Kuala Lumpur and Kota Kinabalu.
Looking at the subsale market, Foo observed that sellers are a lot more realistic today and the gap between asking and concluded prices is narrowing.
“I believe strongly that the price correction has started. A lot more developers are taking note of that. A lot of them are suffering, some of the high-end products are not moving and if you go into their showroom it is very quiet.”
According to CBRE-WTW Research, the total number of luxury condominiums in Kuala Lumpur amounted to 37,824 units as of end-2016 and 86% of existing luxury condominiums are in the RM700-RM1,000 psf range, which could decline to 64% by 2019.
Upscale condominiums priced RM1,001-RM1,500 psf are expected to see the greatest growth averaging 4,000 units per year, making up 23% of total condominiums by 2019.
Within the residential segment, Foo said the biggest challenge is for SOHO/SOVO (small office home office/serviced office virtual office) units where occupancy rates are very low due to oversupply, and will remain so until infrastructure projects are completed in three to four years’ time.
“If all the infrastructure are put in place, living in the city becomes a lot more sexier. Then people will come back to fill up this space. I think people will not mind paying a bit more in terms of rental to compensate for toll, petrol and travelling time,” he said.
“I hope to boost this (SOHO/SOVO segment). Some of them will be able to convert to Airbnb, at least the market will be healthier than a firesale,” he added.
Overall, the residential property segment is expected to be flattish this year in terms of volume and lower in terms of value as more developers shift into affordable housing.
“The only good sign is a lot more developers will venture into affordable housing. If the government pushes hard enough in terms of supply of PR1MA homes and others, the residential segment, I think, will see a slight improvement but overall if you add up the rest, commercial and others, I think it (volume) will be very flat,” said Foo.