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Penola is a great small town encounted when heading north from Mount Gambier heading to Narracorte. A really nice town it is. The place has been made more famous with its early association with Saint Mary MacKillop. Be sure to stay over when visiting Penola. Heritage factors in Penola are presented really well.
The first Europeans to the area were the Austin brothers who arrived in 1840 and established a run of 109 square miles (282 kmē). The first settlers were Scottish -born Alexander Cameron and his wife Margaret in January 1844 after obtaining an occupation license. In April 1850 Cameron obtained 80 acres (0.3 kmē) of freehold land, his station was on a pastoral lease, and established the private town of Panoola, later known as Penola.
By 1850, Brad had built the Royal Oak Hotel and was doing extremely well financially supplying liquor to the many travelers passing through to the Victorian goldfields. Penola Post Office opened around 1852.


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Balungu CHPS compound receive new maternity block
A maternity block has been donated to the Balungu CHPs compound in the Tongo District in the Upper East to support deliveries of babies in communities within the catchment area.
Date Created : 6/29/2018 3:15:37 AM : Story Author : Irene Danso/Ghanadistricts.com
The Nubian Vault Maternity Block built with local materials has a labour room, delivery and wards, as well as toilets and baths valued at about GH¢97,000.00.
The project, which started in June 2017, was made possible by the Dr Nana Gruer Initiative Foundation, an NGO that has partnered the Ghana Health Service (GHS) in medical deliveries over the years.
Professor Lawrence David Gruer, a Scottish Public Health Specialist, speaking at Balungu, said the foundation was in memory of his late Ghanaian wife who was also a medical doctor and loved to help deprived communities.
Professor Gruer expressed the hope that the maternity block which was built by the Nubian Vault Association with funding from friends and organizations will address challenges of maternal care and new born deliveries.
Professor Gruer praised the medical team and individuals, especially, Dr Daniel Bangre, of Peal Deng, an NGO, that was instrumental in the construction of the facility, pledged continuous support to the district and the GHS to improve on medical health delivery in the area.
He praised the medical team at the facility for their hard work and donated a brand new motor bike to them to facilitate their routine monitoring engagements with the pregnant women who visit the facility.
Professor Gruer said the structure was eco- friendly and called on government to emulate that example to address the housing deficits and harsh climatic conditions confronting the country, especially in northern Ghana.
The District Chief Executive of the district Christopher Boatibil Sormifeyima, acknowledged the contributions the technology to the construction industry of the area.
He expressed government’s willingness to collaborate with the Nubian Vault Association to address housing challenges of Ghanaians.

domain: medical


Reviewed by Jackie Kloosterboer
Updated September 11, 2023
Water claims have become the number one cause of home insurance losses in the country, and disaster relief payments have more than doubled every five to ten years since the 1980s.
With extreme weather and flooding events on the rise, there has become a greater need to provide Canadian property owners with proper protection against flooding and access to adequate flood insurance.
A flood map shows which areas are prone to flooding in the event of water level rising to a particular elevation. In a nutshell, a flood map provides stakeholders with the necessary data needed to make smart decisions about asset management, urban planning, and flood risk management.
In terms of insurers, up-to-date flood maps enable them to more accurately assess their risks when considering flood insurance options.
Recognizing that on a federal level, Canada lacked effective flood hazard maps, IBC along with other partners, collaborated on a national flood program led by the private sector. And their main focus was the creation of current flood maps.
These maps took into account river gauge and rainfall data to measure flood extent and depth, flood defense information, historical flood records, snowmelt and terrain data. And then incorporated address data, residential replacement costs, and peril information.
In other countries, like the UK, there are online tools that allow anyone to view the flood risk for their particular region. Simply enter in your location and you can view a very detailed map that highlights likely risk areas. This is certainly a feature any homeowner would review when weighing the pros and cons of relocating to a specific area.
As of February 2016, the IBC now has flood maps that let the bureau and insurance companies assess the flood risk right down to the residential level for both fluvial flooding (which occurs when excessive rainfall over an extended period causes a river to exceed its capacity) and pluvial or surface water flooding (caused when heavy rainfall creates a flood event independent of an overflowing water body).
The data revealed that 20% of Canadian households could be qualified as high-risk, and of those, 10% could be considered very high risk. That’s 1.8 million households.
In 2009, the United States Global Research Program determined that the average precipitation in the U.S. has increased approximately five percent the past 50 years, which leads to increased danger of floods.
Changes in land use also contribute to the potential for flooding; as an area becomes built up, there is less permeable land available to absorb water. Both the U.S. and Canada have seen their urban centers become denser with the sprawl reaching further from the downtown cores.
No big deal, you may say. Most people, don’t believe that a flood will ever affect them. It’s an event that they watch on the news.
Even if it’s statistically unlikely that you’ll be the victim of a flood, it’s unwise to ignore the possibility, because if it does happen, it can wipe out possessions or investment properties in a matter of minutes.
In fact, even though you may consider your property to be at low risk, flood risk is spread across all types of terrain, across income levels and in both rural and urban locations. Some insurers are finding themselves paying more for sewage backups, given that the infrastructure in many municipalities can be overwhelmed by torrential downpours.
If flood insurance is available to you, you may want to consider it if you are endangered or feel vulnerable. The first step is to determine if you live in a flood zone.
The United States has flood maps available online for homeowners to review. Flood maps indicate which areas generally flood if water rises to a certain level. They allow both homeowners and policymakers to make informed decisions about asset management, urban planning, and flood risk management.
The Federal Emergency Management Agency (fema.gov) provides flood mapping services and their maps form the basis for flood insurance rates. More than 20,000 U.S. communities have been placed into flood zones, allowing homeowners there to participate in the National Flood Insurance Program. Insurance rates are determined by risk of flooding. In the two most risky flood zones (V and A), homeowners must ensure that:
The lowest floor elevation must be at or above the base flood elevation — the computed elevation to which floodwater is anticipated to rise during the base flood.
Enclosed areas below the lowest floor can’t be use as living space.
Electrical, heating, ventilation, plumbing and air-conditioning facilities must be elevated to or above the base flood elevation.
ready for an online quote? Your time matters, and so does your stuff. Get a personalized home insurance quote in 5 minutes. That’s less time than it takes to wait in line for coffee.
Until recently, Canada was the only G8 country that didn’t offer flood insurance to homeowners. This meant that it was up to the federal and provincial governments to assist citizens when disaster struck. Luckily for homeowners, change is coming as the incidence of flooding increases.
The Insurance Bureau of Canada recently took part in a private sector effort to the create a new collection of flood maps that take into account river gauge and rainfall data to measure flood extent and depth, flood defence information, historical flood records, snowmelt and terrain data.
The new maps, which were ready early in 2016, are now used by insurance companies to assess flood risk for both fluvial flooding – flooding when excessive rainfall over an extended period causes a river to exceed its capacity — and surface water flooding that is caused when heavy rainfall creates a flood event independent of an overflowing body of water body.
These new maps, which aren’t yet available to the public, indicate that 20 percent of Canadian households are in high-risk areas and 10 percent of those are considered very high risk.
Property flooding is Canada’s leading cause of natural disaster, despite the prominence given to the destruction done by forest fires. Therefore, be certain to determine whether flood damage is covered by your homeowner’s policy.
If you live in a flood zone, insurance can be a godsend. As you think about the necessity for flood insurance, consider these flood facts:
Flash floods can send walls of water from 10 to 15 feet (about 3 to 5 metres) speeding toward your home.
It takes only two feet (about two-thirds of a meter) of rushing water to carry away a vehicle, a frightening thought if you’re inside.
A few inches of water in your home can cause damage that costs many thousands of dollars to repair. This comes out of your pocket if your insurance doesn’t cover it.
Floods can be caused by a variety of events, including as hurricanes, winter storms, snowmelt or heavy rains that don’t drain well.
Don’t be cavalier about the potential damage flooding can cause. Investigate whether it’s something you, as a homeowner, need to address before it’s too late to save your property.
Until the Flood Hazard Mapping Program is available to the public, the best way for a property owner to minimize their risk of flood damage is to conduct a flood risk analysis on your building. You must know the base flood elevation and your building’s finished floor elevations. If your finished floor elevation is above the base flood elevation, you are at low risk of flooding. If the finished floor elevation is below you are at very high risk of flooding.
While you may think your property is at low risk, it is interesting to note that flood risk is spread across all types of topography, in rural areas and cities both young and old, across different income levels and can affect all kinds of buildings and property types.
For instance, despite Vancouver’s rich real estate, relatively young building infrastructure and high livability score, it is the world’s tenth most likely city to suffer flooding.
So, while governments tackle infrastructure and insurance companies conduct risk assessments, a property owner’s best line of defence against flood damage will hopefully soon be that they are properly insured.
Generally, the areas at highest risk of flooding are those at low-lying elevations, located close to water, and those prone to heavy rainfall or snow accumulation. To check specific flood risks, check with your home province or municipality for local flood risk maps.
Some telltale signs that a home has been flooded in the past include: cracks in the foundation, stains on basement walls or flooring, buckled floors, and the presence of mould. When in doubt, consult a qualified home inspector.
Many home insurance policies in Canada do not automatically include coverage for overland flooding, though sewer backup and other water damage may be covered. Always consult your home insurance provider for specifics about your coverage.
Want to learn more? Visit our Home and Personal Safety resource centre to find more information about protecting your family and your home. Or, get an online quote in under 5 minutes and find out how affordable personalized home insurance can be.
About the expert: Jackie Kloosterboer
Jackie Kloosterboer runs a speaking business called Survive It. As a disaster preparedness expert, Jackie facilitates upwards of 100 preparedness workshops annually to individuals and groups, working with them to prepare for whatever disaster comes their way. Jackie is the recipient of the Queens Jubilee Award and the Northwest Preparedness Society Award of Excellence, recognizing outstanding dedication to providing emergency support services and disaster preparedness education.
Check out these related articles:
Get a personalized online home insurance quote in just 5 minutes and see how much money you can save by switching to Square One.
Even when you take precautions, accidents can happen. Home insurance is one way to protect your family against financial losses from accidents. And, home insurance can start from as little as $12/month.


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Lacewing Program for Pregnancy Loss
The Wildflower Intuitive Center knows that when it comes to miscarriage as well as terminations due to fetal or maternal health, families work through a truly unique kind of suffering. We provide support before, during and after the loss of pregnancy, with in-office sessions as well as hospital and home visits as needed. Parents receive access to a provider certified to provide Reiki during procedures. Sessions are provided by a licensed clinician able to focus on preparatory grief and trauma as families face the end of pregnancy. College of medicine certified End of Life Doula components support families through each part of this transformative experience. At Wildflower, we recognize that both the unborn as well as those infants who stay with us only a short time, hold a beauty that has an impact on us through both their presence and absence.


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IndieSider #54: Induction by Bryan Gale
Induction is a time-bending puzzle game from Bryan Gale. A veteran of such AAA studios as Electronic Arts, Gale’s first indie game employs temporal mechanics to create time loops. The only way to pull levers and cross bridges is if a player can be in two places at once — as long as they don’t cause temporal anomalies. The geometric art style is complemented by a soundtrack from Tim Shiel, resulting in an experience that challenges players to rethink their concept of time.
In this week’s IndieSider, Gale and I talk about the time-travel books, movies, and video games that inspired Induction; the mathematical concept for Induction and the physics underlying this game; how working for EA prepared him to be an indie developer; the development and feedback opportunities Gale enjoyed at Stugan and EGX; and what other platforms we’ll be seeing Induction on.
Links mentioned in this episode:
- Bryan Gale on Twitter
- Stugan — a non-profit accelerator program for talented game developers
- Time-travel movies & books
- Time-travel video games
- Blinx: The Time Sweeper
- Hologram Time Traveler (Sega)
- Still Time by Alan Zucconi
- Thomas Was Alone
- Monument Valley
- Tim Shiel on Soundcloud

domain: entertainment


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Design and synthesis of novel quinacrine-[1,3]-thiazinan-4-one hybrids for their anti-breast cancer activity
Abstract In an attempt to develop effective and safe anticancer agents, we designed, synthesized and examined 23 novel quinacrine (QC) derivatives by combining the 9-aminoacridine scaffold and the [1,3]thiazinan-4-ones group. Most of these hybrids showed strong anticancer activities, among which 3-(3-(6-chloro-2-methoxyacridin-9-ylamino)propyl)-2-(thiophen-2-yl)-1,3-thiazinan-4-one ( 25 ; VR151 ) effectively killed many different cancer cell types, including eight breast cancer cell lines with different genetic background, two prostate cancer and two lung cancer cell lines. In contrast, compound 25 is less effective against non-cancer cells, suggesting it may be less toxic to humans. Our data showed that cancer cells are arrested in S phase for a prolonged period due to the down-regulation of DNA replication, leading to eventual cell death. We have also shown that the S phase arrest may be resulted by the down-regulation of cyclin A coupled with the continued up-regulation of cyclin E, which coincide with the down-regulation of mTor-S6K and mTor-4EBP1 pathways. Highlights A series of novel quinacrine derived thiazinan-4-ones were synthesized. The detailed SARs of the derivatives were summarized. Compound 25 is substantially effective than the parental quinacrine. Compound 25 bind to certain protein essential for DNA replication without causing DNA damage, resulting in the inhibition of DNA replication and/or the down-regulation of cyclin A. Graphical abstract [DISPLAY OMISSION]
유료 다운로드의 경우 해당 사이트의 정책에 따라 신규 회원가입, 로그인, 유료 구매 등이 필요할 수 있습니다. 해당 사이트에서 발생하는 귀하의 모든 정보활동은 NDSL의 서비스 정책과 무관합니다.
원문복사신청을 하시면, 일부 해외 인쇄학술지의 경우 외국학술지지원센터(FRIC)에서
무료 원문복사 서비스를 제공합니다.
NDSL에서는 해당 원문을 복사서비스하고 있습니다. 위의 원문복사신청 또는 장바구니 담기를 통하여 원문복사서비스 이용이 가능합니다.
- 이 논문과 함께 출판된 논문 + 더보기

domain: literature


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The key questions following Henrik Stenson’s Ryder Cup captaincy appointment
Henrik Stenson has been chosen as the man to lead Europe in the 2023 Ryder Cup as they try to bounce back from a record-breaking defeat.
The Swede will go head-to-head with fellow former Open champion Zach Johnson and here, the PA news agency takes a look at what sort of skipper he may be and the challenges facing him.
His CV certainly stands up and marks him out as one of the finest European players of his generation. A record-breaking major champion after defeating Phil Mickelson in an unforgettable Sunday showdown for the Claret Jug at Troon in 2016, he is not one to be intimidated by the task at hand. His penchant for the big stage is also evidenced in his victories at the 2007 WGC Match Play, 2009 Players Championship, 2013 Tour Championship and two wins at the DP World Tour Championship. Those triumphs along with nine others across the PGA and DP World Tours have brought him a FedEx Cup and two Race to Dubai titles. Stenson’s on-course record will no doubt have the respect of his team and those in the opposing locker room.
What about his Ryder Cup record?
Stenson had his prime playing years at a time when Europe were utterly dominant in the Ryder Cup. He made his debut in 2006 at the K Club and won 1.5 points, holing the winning putt as Europe completed a second-consecutive then-record 18.5-9.5 win. He once again claimed 1.5 points in a losing effort in 2008 but then missed out in 2010 and 2012 due to a combination of injury, illness and lack of form. He slipped as low as 230 in the world rankings in 2012 but a stunning upturn in form the following year saw him standing on the first tee alongside Justin Rose at Gleneagles in 2014. The duo would claim three points together as Europe won the cup again and while they were paired three times in 2016, they would take just a single point, with Stenson also winning his singles match as Europe lost for the first time in eight years. Stenson needed a captain’s pick in 2018 but repaid the faith shown by Thomas Bjorn, winning three points from three, including two more alongside Rose, to take his career tally to 11.
What kind of captain will he be?
One thing for sure is the European team room will be a fun place to be. Stenson is renowned for being one of golf’s funny men, with European Ryder Cup director Guy Kinnings even citing his “dry sense of humour” and “fantastic warm personality” when announcing his selection. Stenson was asked after the birth of his daughter Alice in October 2014 whether he and his wife Emma planned to have more children and joked that he hadn’t “done any official snip-snips as of now”. The assembled reporters burst out laughing and when his questioner insisted that was not what he asked, Stenson replied: “But that’s what you wanted to know. You just didn’t have the balls to ask.” He even managed to win over the crowd at Hazeltine in a 2016 Ryder Cup where the hostile behaviour of the home crowd was often in question. After putting his opening tee-shot in the singles into an area full of portable toilets, the gleeful home crowd soon came round to Stenson’s side when he said: “Well, that’s a s*** shot.” Also the star of many of the DP World Tour’s social media videos, his combination of iceman on the course and joker off it could be the perfect combination for Europe.
Who did he beat to the job?
For a long time, it was assumed that Lee Westwood would be Europe’s leader in 2023 but when the Englishman dropped out to concentrate on a playing career that still sees him around the world’s top 50, the field was wide open. Luke Donald then became many people’s favourite, with Sergio Garcia backing his former Ryder Cup playing partner for the role, while Stenson was mentioned alongside countryman Robert Karlsson and Scot Paul Lawrie. In the end, the committee – made up of the three most recent captains Padraig Harrington, Thomas Bjorn and Darren Clarke along with DP World Tour player director David Howell and chief executive Keith Pelley – went for Stenson. Stenson is 45 and with Lawrie, 53, Karlsson, 52, Westwood, 48, Donald, 44, Garcia, 42, Ian Poulter, 46, and Graeme McDowell, 42, among those queueing up for the top job, future committees may have to decide which of Europe’s golden generation will miss out.
Will he have a team that can win?
After the 19-9 drubbing at Whistling Straits, it is possible that 2023 will be too soon for a European renaissance. Jon Rahm, Viktor Hovland and Rory McIlroy will continue to be shining lights for Europe for years to come but Tyrrell Hatton is the only other European currently in the world’s top 20. Paul Casey, 44, is likely to have another Ryder Cup in him, while the likes of Matt Fitzpatrick, Thomas Pieters, Tommy Fleetwood and Shane Lowry have already played in the biennial showpiece. But hope may come from other sources, with Irishman Seamus Power making his mark on the PGA Tour and Danish identical twins Nicolai and Rasmus Hojgaard establishing themselves as stars on the DP World Tour. Rome may come too soon for Europe’s new generation to challenge the power of the United States but Stenson can make his mark on the rising stars.
What about the opposition?
We may be well over a year from knowing the teams but there is no doubt that the Americans will take a young, hungry and incredibly talented set of players to Marco Simone Golf and Country Club. Stars of 2021 Collin Morikawa, Scottie Scheffler and Xander Schauffele will still be in their 20s, while Patrick Cantlay, Justin Thomas, Bryson DeChambeau, Jordan Spieth and Brooks Koepka will only be in their early 30s. Even five-point hero Dustin Johnson will not yet be 40 as the Americans look to establish a period of dominance similar to that enjoyed by Europe in recent years. And in skipper Zach Johnson they have taken a page out of Europe’s captaincy book. At 46, he is young enough to still have a connection with his younger players and has also served as a vice captain – not to mention won two major championships. If Stenson can guide Europe to victory against such a strong United States team in 2023, he may join the list of great European captains.
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domain: sports


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The salon owner accused of "setting up" House Speaker Nancy Pelosi, D-Calif., is thanking supporters who have contributed $300,000 to a crowdfunding account set up to help move her business after she received threats.
Erica Kious, the owner of San Francisco's eSalon, got more than $300,000 in under a week from a GoFundMe account set up on her behalf. Now, she plans to use the money to pay off debts and relocate her salon.
"I am very humbled and grateful to have received such an outpouring of kindness, empathy, and generosity from people I don't even know and from all walks of life and all sides of the political spectrum," Kious told Fox News. "It's a powerful reminder that the common things that bind us all together as Americans are far more meaningful and lasting than political and ideological differences that get so much attention and focus."
Former Nevada GOP Chairwoman Amy Tarkanian set up the account for Kious.
"I'm honored to help a friend and to have been a part of this," Tarkanian wrote on the GoFundMe page. "If it's safe enough for NV Gov Sisolak to enjoy dining out while listening to 'ambiance' music, NY Gov Cuomo to walk his dog or hop on a plane without a mask, or for CA Speaker Pelosi to not only make an appointment in her district but then get her hair done without wearing a mask, then it should be ok for the rest of us to open safely and resume living!"
Pelosi went to the salon in late August in violation of San Francisco's coronavirus order on visiting salons. Kious later made public security video footage of Pelosi walking around the salon without a mask.
"I take responsibility for trusting the word of a neighborhood salon that I've been to over the years many times and that when they said what we're able to accommodate people, one person at a time, and that we can set up that time, I trusted that," Pelosi said at a press conference last week. "So, I take responsibility for falling for a setup."
Pelosi added the salon owner owes her an apology. The House speaker neglected to apologize, however, for violating the city's coronavirus order.
© 2022 Newsmax. All rights reserved.

domain: politics


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Make a New Year’s resolution to see better entertainment and eat better food! Then you can kill two birds with one stone at Disney Springs by watching Cirque du Soleil’s newest show and eating the accompanying donut from Everglazed!
“Drawn to Life” is Cirque’s latest venture at Disney Springs. It is a celebration of Disney animation using daring acrobatics and choreography to spark our imagination. The stage is transformed into a giant animation table during the performance when classic Disney animation is revived in a brand new way. The show includes all-new Disney animation and an original score that is inspired by Disney music! To honor the incredible work and artistic fervor behind such a project, Everglazed Donuts & Cold Brew has designed the perfect donut to complement your viewing experience.
Related – These Mickey Donut Cookies Make A Magical Dessert!
Dipped in blue frosting with a swirl of blue and white buttercream frosting, crowned with an edible Cirque logo, an (inedible) artist’s palette, and golden star sprinkles, this is a pretty and fluffy yeast donut. This bright beauty looks exciting enough to take center stage! It’s a new year, why not try a new donut?
Everglazed Donuts & Cold Brew opens daily at 9 AM in Disney Springs. Be sure to order one of their fantastic coffee drinks while you’re there. You also need to go watch Cirque du Soleil’s “Drawn to Life,” performances now through December 31st, 2022!
Photos courtesy of Everglazed/Disney
Let our friends at Destinations to Travel help you book your next Disney Vacation. They are the preferred Travel Agency of Chip and Company and Disney Addicts, and who we use ourselves.
Get started below for your FREE No Obligation Quote.
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For the BEST in Disney, Universal, Dollywood, and SeaWorld Theme Park News, Entertainment, Merchandise & More follow us on, Facebook, Instagram, and Youtube. Don't forget to check out the Chip and Company Radio Network too!

domain: artistic


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Eutectic mixture of local anaesthetics (EMLA) cream is used routinely as a local anaesthetic prior to venepuncture in children. Despite this, however, a significant proportion of children will still be distressed. Cognitive-behavioural interventions, such as distraction by breathing and blowing exercises, have been used and found to be helpful as alternative coping strategies. There is, however, a paucity of data regarding effectiveness. We have evaluated the efficacy of distraction therapy as a coping strategy before and during venepuncture, and in these children evaluated the need for EMLA using a prospective, randomized, double-blind, placebo-controlled clinical trial. Twenty-eight children attending for venepuncture were recruited, median age 6 y (range 4-8 y), and randomly allocated to receive either EMLA or a placebo cream. All were given distraction therapy prior to and during the procedure by a play specialist. Venepuncture was carried out by one investigator. A modified paediatric pain assessment chart was used for objective pain score at the end of the procedure. After one exclusion, the treatment group (17 children) and the placebo group (10 children) were similar: median age of 6 and 7 y (range 4-8), median baseline and post-procedure heart rate and oxygen saturation. The median (interquartile range) for total pain score in the treatment group was 1 (0 to 4.5) and in the control group 1 (0 to 2.3). There was no significant difference in pain score between the two groups (Mann-Whitney test, p = 0.7). The 95% confidence interval for the difference in pain score was -1.0 to +3.0.
Conclusions: The low pain score in both groups suggests the effectiveness of distraction therapy, although factors such as skill of the operator and previous experience of the patient group are of relevance. There was no significant difference in the pain score between the EMLA and placebo groups, suggesting that in this age group if carefully selected children receive distraction during venepuncture EMLA may not be necessary.


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Sterling Silver Chip Cut Carnelian Earrings
Handcrafted Pearl Quartz And Periodot Earrings
Orange Floral Princess
Cultured pearl and quartz flower necklace
Multicolored Multi-Gemstone Beaded Necklace from Thailand
Thai Artisan Crafted Modern Carnelian and Calcite Necklace
Fair Trade Jewelry Artisan Crafted Beaded Necklace
Gladiolus in Bloom
Carnelian beaded flower necklace
Golden Daisy Chain
Hand Crafted Carnelian and Glass Bead Necklace...
Bright Bohemian Bouquet
Handcrafted Multicolor Quartz Pendant...
Succulent Garden in Red-Orange
Red-Orange Multi-Gemstone Beaded...
Aventurine and Garnet Beaded Necklace
Turquoise Calcite and Carnelian Bracelet with Smoky...
Fair Trade Artisan Necklace with Carnelian and Blue...
Handmade Pearl and Gemstone Cluster Earrings

domain: design


How to Diagnose Auto A/C Expansion Valve Probeby Lee Sallings
When liquid refrigerant is forced through a restricted opening, it changes from a liquid to a gas. This change of state causes the refrigerant to become cold, and as it passes through the system, it absorbs heat from the passenger compartment. The vehicle's air-conditioning relies on this change of state to operate, and the expansion valve provides the restriction used to control the volume and pressure flowing through the system. Diagnoses of expansion valve malfunctions are done with an A/C gauge set.
Attach the gauges to the A/C system by locating the low-pressure and high-pressure service ports. The low-pressure port can be found on the low side line between the accumulator (sometimes on the accumulator) and the compressor. The accumulator is the cylindrical part attached to the system near the passenger side of the firewall. The high-pressure port is located on the high side line between the condenser and evaporator. The condenser is the radiator-like part located in the front of the vehicle, and the evaporator is located under the dash. Make sure the valves are closed on the gauge assembly, and attach the quick-disconnect hoses to the service ports.
Start the engine and set the A/C controls to max A/C, medium blower speed and recirculating air. Allow the system to run for five minutes for pressures to stabilize.
Normal gauge readings will be between 30 and 45 psi on the low side, and 200 to 350 psi on the high side. The expansion valve can fail in one of two ways. When stuck open, it allows two much refrigerant flow, and a drop in high side pressure. A gauge reading of less than 200 psi on the high side will be seen when this happens. When stuck closed, a higher than normal high side reading will be seen. Typically, this will be over 400 psi and climb until the high-pressure switch shuts down the system. Very low or very high readings on the high-side gauge indicate a faulty expansion valve.
Things You'll Need
- A/C gauge set
Lee Sallings is a freelance writer from Fort Worth, Texas. Specializing in website content and design for the automobile enthusiast, he also has many years of experience in the auto repair industry. He has written Web content for eHow, and designed the DIY-Auto-Repair.com website. He began his writing career developing and teaching automotive technical training programs.


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You can assemble this glorious cake up to two days ahead; store at room temp. Also, you can freeze cooled layers up to a month in plastic wrap and aluminum foil. The sweet-tart Strawberry-Lemonade Jam and Strawberry Frosting make for a delicious finish.
You'll fall in love with this too-good-to-be-true strawberry cake. Fluffy whipped frosting made with marscapone cheese, sugar, whipping cream, and vanilla and almond extracts is the perfect finishing touch. We love the presentation of cake slices with upright strawberries between the layers. When it comes down to the details, this sweet confection takes the cake.
We used 6 (8-inch) disposable aluminum foil cake pans, so we could fill all the pans at once. This way, if you bake the layers in batches, the second batch is ready to go in the oven as soon as the first is done.

domain: food


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"replacement knee surgery"
About: Luton & Dunstable Hospital Luton & Dunstable Hospital Luton LU4 0DZ
Posted by cynthia birt
I would like to give my thanks,praise and gratitude to all the staff,nurses,surgeons,anesthetists,students,in fact anyone and everyone that was involved in my knee replacement operation on Monday 9th june at Luton and Dunstable Orthopaedic dept, and after care in ward 20 bed5.What a team you all seem to work together,know what you are talking about and nothing was to much trouble. So a big thankyou to you all

domain: health


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IT'S common knowledge that Scotland is one of the most beautiful countries in the world
But let's face it, some people just don't believe how great our bonnie wee country is.
Much of Scotland's beauty is often overshadowed by the fact we often witness weather that resembles five seasons in a day.
But these gorgeous and unbelievable pictures of some of the country's most enchanting spots prove how Scotland wins the day when it comes to breathtaking scenery.
And they might even tempt you to visit a few parts you've not been to yet.
Find out why Scotland is the perfect holiday destination .
For more stunning pictures of Scotland click here .

domain: travel


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McCreevy/Market regulation26 Oct 2007
EU market chief cautions against rigid transparency rules
Reckless investment practices and bad liquidity management contributed to the global credit market crisis but rigid transparency rules are not the right answer, Charlie McCreevy, the European internal market commissioner, will warn on Friday.
In a speech in Dublin, McCreevy will denounce the â€œirresponsible lending, blind investing, bad liquidity management, excessive stretching of rating agency brands and defective value at risk modellingâ€? that prompted the turmoil of recent months.
However, the commissioner, one of the EUâ€™s most prominent exponents of free-market thinking, will caution against a rush to regulate, saying rules that enforce transparency in financial markets can sometimes backfire, spreading panic and moral hazard across the system.
McCreevy will also take issue with credit ratings agencies, saying the unprecedented discounts on much AAA-rated paper since the turmoil erupted underline how the agencies have lost market trust and must improve their governance by tackling conflicts of interest.

domain: news


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Have some early prom pictures! In my game, Willow and Amelia are aging up soon, so I wanted to get these before I couldn’t. I love them all, they’re all so cute cx
I possibly will have a storyline(s) at ‘prom’, but in between that, there will be a mixture of story and gameplay pictures.
So, they all have ship names, ‘cause I wanted them to.
Willow + Reese = Rillow
Brandon + Jenny = Brenny
Amelia + Mason = Amelson or Amason lol I couldn’t choose.

domain: hobby


Jeff Merkley is a new Senator for me, although I was proud to be a supporter-from-afar when he ran for the Senate from Oregon in 2008. I like his taking-questions-from-constituents YouTubes and was happy to see Atrios featured one of them on today’s Eschaton front page.
|By: Cenk Uygur Monday July 26, 2010 2:58 am|
There is now a list going around in conservative websites purporting to be “The List” of media participants in Journolist. It’s fake. How do I know? I’m on The List. And I was never on Journolist.
|By: TheMediaConsortium Tuesday July 20, 2010 9:54 am|
With the Wall Street reform bill finally cleared through Congress, activists and intellectuals are pushing hard to make sure that this bill isn’t the last word Congress utters about Big Finance. We need deeper and more robust reforms, but it’s also critical to ensure that the new bill is implemented as effectively as possible. Part of that means appointing officials with a proven record as robust reformers—people like Elizabeth Warren.
|By: Jim White Saturday July 17, 2010 5:47 am|
Laurie Anderson’s terrific performance of “Only an expert (can deal with the problem)” on The Late Show Wednesday night provokes thought on our current reliance on precisely the wrong experts to deal with the problems we face.
|By: Cenk Uygur Friday July 16, 2010 1:24 pm|
The final financial reform package has been dramatically watered down and is riddled with loopholes. But its supporters (and some critics) say that we shouldn’t worry because it at least allows regulators to get tough on the financial industry later — if they think it’s necessary. That is actually true. It does have such provisions.
|By: masaccio Friday July 16, 2010 9:00 am|
Timothy Geithner doesn’t like Elizabeth Warren, she is mean to him. Who, then, can we get to head up the Consumer Financial Protection Bureau?
|By: Leen Friday July 16, 2010 6:53 am|
|By: Lynn Parramore Wednesday July 14, 2010 1:19 pm|
In an exclusive interview, New Deal 2.0 editor Lynn Parramore discusses financial reform with TARP watchdog and consumer advocate Elizabeth Warren.
|By: Cynthia Kouril Wednesday July 7, 2010 7:28 am|
I had been waiting and hoping that some ambitious team of investigative reporters would wake up to this story an go put it on the front page of a major daily paper and b doing so, get the general public educated and Capital Hill all fired up about DOING something to keep people in their homes. By some miracle, Capital Hill has cut out the dead tree middleman and appears to be awakening to this issue without help from the traditional media.
|By: Richard Zombeck Sunday April 25, 2010 9:57 am|
When I get to D.C. I want to show Senators John Kerry and Scott Brown why this country needs financial reform and why we need their vote on the The Restoring American Financial Stability Act. Your letters and stories will serve as irrefutable evidence that Congress needs to reform the way Wall Street has been doing business.


Fantasy Radio, the Devizes based radio station has re-launched for August on frequency 87.9fm. They air for the whole of August, whilst applying for their full time broadcasting licence.
In order to obtain said licence they have to for-fill an awful lot of criteria, and one of the things we at Sheer Music are going to do is give Fantasy a real LOCAL focus.
Starting THIS SATURDAY the 6th of August former co-promoter Matthew Corbett, will be presenting his show, Matthew And Friends, a 2 hour show starting around 7 / 8pm, and finishing around 10pm.
I Kieran Moore will be Matthews first guest, providing him with the local round up on Devizes, and our local scene.
I’ll be providing Matthew with a lot of local music, so if you’ve every had anything to do with me in the past year or so, don’t worry you’ll be in the mix. I’ll even try and get it over the PA in the Lamb 😉
There will be a guest interview with Sailors front man and sticksman, Alex Share and Henry Cox, respectively, who will be discussing their new EP, which Matthew will play, along with a live acoustic session from Georgie Vale too! (Georgie to be confirmed)
Add into the mix local film buff, Phil Hardy BA, who will be giving us a run down on local cinema and films, along with Matthews eclectic taste in music this really is a exciting prospect for out local music scene.
Over the coming four Saturdays in August, there will be a massive theme developed, with some great talking points coming up (3d Cinema, edge of your seat live sessions, streaming of a live event etc) so please please, start your Saturday night out with a little listen to Matthew And Friends and Get Involved!


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Gardening is how I relax. It's another form of creating and playing with colors.
Oscar de la Renta
Thanks for your input!
pennyc310 on The Flowers of Torch Lake Maureen Sanders on The Flowers of Torch Lake Dorothy Clore on The “Chilly” of To… Jane Carpenter on The “Chilly” of To…
“Before Today” Blogs
Tag Archives: snow
The Sunshine of Torch Lake
All summer long… we bake in the sun & warm air. Then winter comes… We watch the snow fall down & the drifts pile up. We bundle up against the temperatures falling down. We build snow forts & snow men. … Continue reading
Posted in Just Down the Road Tagged alden MI, Mackinac Bridge, Mackinaw City, nature, northern MI, photography, snow, St. Ignace, Torch Lake 1 Comment
A Walk in th Snowy Woods
Its winter… & I’m going for a walk in the snowy woods. You come too. We’ll wear keep-your-head-warm hats, hand-clapping-mittens, & snow-stomping-boots. We’ll see trees without leaves, maple, oak, birch, & beech. Their trunks & branches standing tall in … Continue reading
Posted in Just Down the Road Tagged alden MI, hot chocolate, nature, Northern Michigan, photography, Poetry, snow, Torch Lake, walking in the woods, warm mittens, winter 2 Comments
Semi Wordless Wednesday
Even a Winter Garden… isn’t safe from the dreaded Snow Chicken!!!
Posted in Turquoise Life Tagged alden MI, chickens, Gardening, Humor, nature, Nothern MI, photography, snow, Torch Lake, winter 2 Comments


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This past summer I felt very discouraged to pray. Not unmotivated to pray, but discouraged. I knew in my head that God was listening to my prayers, but I did not know it in my heart. I felt this strange obligation for my prayers to be at least 30 minutes long or else they wouldn’t count. I chatted with a spiritual director about this and they led me through a listening exercise. At that moment I asked God what was going on, why have I been feeling this way? The Lord, as always, was kind and he responded so gently to me. He prompted this realization.
I had been thinking of prayer as a letter, the kind that takes days and days to arrive. When you send a letter of this caliber, you probably want it to be extensive. After all, it took a lot of effort for the letter to make it to its recipient. This is why I felt like any prayer that wasn't fancy or well worded or long enough wasn't being listened to. Rather than sending a letter worth reading, I felt like I was leaving God Post-It notes that he didn’t have time for.
As I came this realization, I turned to the truths of his very own word:
1 John 5:14 - We can have confidence that he hears us.
1 Peter 5:7 - He cares for all of my anxieties.
Romans:38-39 - Nothing can separate me from his love.
Matthew 28:20 - He is always with me, until the end of time.
Psalm 23:4 - I do not have to fear, he is with me, and he comforts me.
Ephesians 2:8 - I have been saved by grace, through faith, not by anything I can do or have done.
As I thought about these truths, my Father reminded me that I had been thinking of prayer from a human perspective, not from his perspective. When I pray, I am not sending a letter, or even a Post-It note. I am having a real time conversation with the God of the universe whose Spirit is in me and who has promised to be with me until the end of time. He gave me this picture:
Imagine going to a coffee shop with some friends to get some work done. You’re all working on your own thing, but you’re doing so together. Every once in a while you look up from your work and exchange a few words. You have short conversations as you work alongside each other.
Jesus reminded me that he is not far away. That I don’t have to leave Post-Its or write him a letter, but rather as I go about my day, I can stop what I am doing and have a few words with him. He is there right beside me, listening and responding to my thoughts. I do not want to minimize the importance and the delight it is to spend extended time with the Lord, but I want to remind you that there are no time minimums on prayer. You do not have to prove that you are worth being listened to. You have been made worthy by the blood of Christ that was spilled for you. As you go about your busy, fall days, feel free to stop and exchange just a couple of sentences with your Father. He is listening and he is so excited to spend time at life’s coffee shop with you.


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DOM AND DELIGHT
Tarbell’s Champagne Tasting for Twelve in Phoenix
Surround yourself with thousands of bottles of wine in the intimate and exclusive setting of Tarbell’s Wine Store. You’ll mix and mingle while enjoying a decadent, private Dom Perignon champagne tasting for twelve (12).
You and your friends will indulge in Dom Perignon, the world’s most celebrated luxury vintage champagne, and an array of mouth-watering food pairings designed by Iron Chef Winner and host of PBS Plate and Pour, Mark Tarbell.
The Dom Perignon will be expertly paired with tasting bites made up of the classics, such as frico, caviar and lobster, and new surprises exploring caponata, pan-seared diver scallop, and smoked BBQ.
Known for his ability to symphonically pair food and wine, Mark Tarbell will curate a fun evening for you all to remember! Mark’s restaurants and their team have been awarded more than 50 local and national accolades including Food and Wine Magazine Best Restaurant and Wine Spectators Best Award of Excellence for its wine list.
Donated by: Tarbell’s Restaurant
Restrictions: Dates based on availability. Excludes holidays. Expiration date: April 17, 2022.
Watch Video Intro


Nominations must be submitted electronically by April 28, 2021.
Budget 2021: PSAC welcomes historic child care funding and $15 minimum wage
PSAC welcomes the measures in the 2021 budget that respond to the needs of Canadians hardest hit by the pandemic.
PSAC Scholarship Program – 2021
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Stop the taxation of Phoenix general damages – Call your MP!
Registration Form: PSAC Atlantic Triennial Convention
PSAC Members Reach Tentative Agreement with Bryony House
FOR IMMEDIATE RELEASEFebruary 19, 2021 PSAC Members Reach Tentative Agreement with Bryony House HALIFAX, NS – A tentative agreement was reachedlate in…
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Louisiana-based Dupré Logistics is a privately held, asset-based provider of transportation and logistics services that include energy and chemical transport, dedicated truck transportation, site logistics, and freight brokerage. Dupré specializes in tanker, hazmat, petrochemical transportation and complex supply chain solutions in industrial and consumer products.
In two years, Dupré has more than tripled the size of its Strategic Capacity Services group and the company plans to double its revenue in the next four years. Having the right technology partners is a key part of the company’s growth strategy and, to support the aggressive growth of its brokerage division, Dupré chose to deploy the Descartes MacroPoint freight visibility solution. Dupré understands, from experience, that driver adoption and coverage are critical for accurate and timely freight visibility. With the highest driver adoption rate and the largest carrier visibility network in the industry, the company believes that Descartes MacroPoint is the right solution for its customers and carriers.
4 reasons to use Descartes MacroPoint for Freight Visibility
With greater customer expectations for visibility and increasingly constrained carrier capacity, logistics organizations need a platform like Descartes MacroPoint to proactively manage transportation by taking advantage of advanced freight visibility.
With Descartes MacroPoint, shippers, brokers and 3PLs have:
- a cost-effective freight visibility solution engineered to track ANY shipment they have tendered to a third-party carrier.
- Integrated with a wide range of transportation management systems (TMS) systems,
- Descartes MacroPoint automates the entire process, eliminating the need for drivers to check in with dispatchers, and for shippers and brokers to check in with carriers.
- To date, over 1 million drivers and 2 to 3 million trucks in North America are a part of the “Descartes MacroPoint–enabled” network.
How Freight Visibility Software Improves Transportation Performance
The cloud-based Descartes MacroPoint freight tracking platform gives logistics service providers, like Dupré Logistics, carriers, brokers and shippers, real-time visibility into shipment status.
- closely monitor, predict, and manage by exception the real-time movement of all their freight in one portal
- take proactive, corrective action before any potential supply chain disruptions occur.
- use this robust, automated solution - companies of all sizes can eliminate the need for time-consuming and ineffective check calls with carriers to ascertain load location details, streamline transportation operations, and
- improve communication about in-transit freight across the supply chain.
Read more about Descartes MacroPoint solutions and learn about other Descartes solutions for Transportation Management Solutions.


Performers come together to benefit two local non-profits, Eight O'Clock Theatre and Gulf Coast Dance Theater.
TAMPA BAY, FLORIDA, UNITED STATES, October 26, 2020 /EINPresswire.com/ — On Sunday, November 1, a slate of award-winning performing artists are leading the charge to normalcy and a revitalized celebration of Life!
Live performance art almost disappeared for eight months, crushed by caution and divided by desperation. Now the dark time is over! Dancers and singers of national and international fame will unite for two performances at District Dance Academy in Largo, to support two local non-profit art groups.
David Pomeranz, of 22 platinum and 18 gold record fame, will share his mercury-sliding-on-syrup voice, melting you into the arms of your loved one. Mike Foncannon and Ellie Figgins will pump you up with the Lindy Hop and more. Hana-Li Pendery wrings every drop of your and her emotion from every song she sings. Jared Brunson’s ballet skills have impressed across the country and received high acclaim from Dance Magazine.
Joanne X Andrews is a soprano who plays with her voice and music with the energy of a child playing tag. Hugo Miguez and Stacy Kay, the owners of District Dance Academy and international dance partners, choreographers and dance judges will demonstrate their winning style of West Coast Swing. This is in addition to phenomenal artists from the Gulf Coast Dance Theater and Eight O'Clock Theatre themselves; Latoya McCormick, Rachel Crissman, Sarah Roehm, and Paula Broadwater to name a few.
Organized by Producer, Choreographer and Best of the Bay’s 2018 Best Dancer Lyla Menkhaus, these two performances, at 5:00 p.m. and 8:00 p.m., will be your only chance ever to experience the artistry of many of these artists, who are usually on tour or who live in other areas. The groups these artists are supporting are the Eight O’Clock Theatre (www.eightoclocktheatre.com), a community theater group with impressive credentials and the Gulf Coast Dance Theater, the non-profit performing company of Gulf Coast Dancenter (gulfcoastdancenter.com) that trains young people in ballet and other styles to the highest standard.
Do not let this rarest of rare opportunities pass you by. You will remember this evening forever.
For more information and to virtual and in-person tickets, visit unitedtosavethearts.com.
Specialized seating and virtual attendance available. Social guidelines in place. Masks required.
Press release written by Don Dewsnap
Artists Untited to Save the Arts
Source: EIN Presswire


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High interstitial fluid pressure - an obstacle in cancer therapy.
2004 (English)In: Nat Rev Cancer, ISSN 1474-175X, Vol. 4, no 10, 806-13 p.Article in journal (Refereed) Published
Many solid tumours show an increased interstitial fluid pressure (IFP), which forms a barrier to transcapillary transport. This barrier is an obstacle in tumour treatment, as it results in inefficient uptake of therapeutic agents. There are a number of factors that contribute to increased IFP in the tumour, such as vessel abnormalities, fibrosis and contraction of the interstitial matrix. Lowering the tumour IFP with specific signal-transduction antagonists might be a useful approach to improving anticancer drug efficacy.
Place, publisher, year, edition, pages
2004. Vol. 4, no 10, 806-13 p.
Alprostadil/pharmacology, Animals, Antineoplastic Agents/*pharmacokinetics, Biological Transport, Bradykinin/antagonists & inhibitors, Extracellular Fluid/*physiology, Humans, Hyaluronoglucosaminidase/pharmacology, Hydrostatic Pressure, Mice, Neoplasms/blood supply/drug therapy/*physiopathology, Niacinamide/pharmacology, Platelet-Derived Growth Factor/antagonists & inhibitors, Research Support; Non-U.S. Gov't, Signal Transduction/drug effects, Transforming Growth Factor beta/antagonists & inhibitors, Tumor Necrosis Factor-alpha/antagonists & inhibitors, Vascular Endothelial Growth Factor A/antagonists & inhibitors
IdentifiersURN: urn:nbn:se:uu:diva-67997PubMedID: 15510161OAI: oai:DiVA.org:uu-67997DiVA: diva2:95908


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William Lance "The Big Puma" Berkman (born February 10, 1976, in Waco, Texas) is a Major League Baseball player for the Houston Astros. Berkman is known as "The Big Puma," a nickname he coined in jest while on a sports talk radio show. His official listed height is six feet, one inch, and his weight is 220 pounds (100 kg). Berkman is a switch-hitting outfielder/first baseman who throws left-handed.
Berkman graduated from Canyon High School in New Braunfels, Texas in 1994.
He then attended Rice University playing on the Owls baseball team, where he was named the 1997 National College Player of the Year, playing for the legendary Wayne Graham, as well as named a first team All-America by Collegiate Baseball Magazine, Baseball America and The Sporting News. He was invited to visit the White House and dine with President Clinton along with the rest of the Baseball America honorees.
Throughout college, he batted a collective .385 with 67 home runs and 272 RBI. His 41 home runs in 1997 ranked third-most in NCAA history. That year he also made the all-time record book in RBI (2nd-134), slugging percentage (6th-1.031) and total bases (4th-263) while leading the Rice Owls to their first
CHICAGO (AP) — Houston outfielder George Springer sat out the Astros' 11-7 win over the Chicago White Sox because of soreness in his right quad and knee.
The day off on Sunday was mostly precautionary, and Springer expects to play Tuesday ...
GILBERTVILLE -- Lance Berkman may have recently retired from professional baseball, but his "Puma" nickname lives on.
Silenced by North Tama ace Brody Hulme all afternoon, Don Bosco senior Shane "Puma" Becker -- an avid fan of Berkman from his days in ...


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Your hospital stay, where your cardiologist told you that your heart was failing, has come to an end. You’re ready to - finally - return home with a handful of prescriptions, for drugs and for several lifestyle changes sanctioned by the doctor. Instead, the cardiologist strongly recommends a pitstop at a skilled nursing facility, ensuring you that after a certain amount of time - days, weeks, months - you’ll be ready to go home.
But is the pitstop truly necessary? Even more important, is a stay at a skilled nursing facility negatively affecting the health of heart failure patients? These are the questions experts from Mayo Clinic set out to answer definitively, hoping to understand the “complete experience” of heart failure patients traveling between the hospital, nursing facilities, and home.
"This required linked data from across the community and across the lives of these patients,” explained first author of their study published in Mayo Clinic Proceedings, Sheila Manemann.
During heart failure, the heart, a muscle, cannot function like it needs to in order to pump oxygenated blood to the body’s tissues. Depending on whether it is the left or right side of the muscle that is dysfunctional, a variety of negative effects take place: fluid buildup, shortness of breath, fatigue. Men and women, young and old fall victim to heart failure; the condition affects nearly six million people in the United States alone. There exists no “cure” to bring the heart back to pumping like a fully functioning muscle, but medical interventions and lifestyle changes can improve the quality of a person’s life despite their living with heart failure.
1,498 patients diagnosed with heart failure and living in Minnesota became the subjects of the Mayo Clinic study. Researchers took into account several risk factors and preexisting conditions that could potentially confound the results, and then they began to learn the truth about the effects on patients who spend time in a skilled nursing facility after being in the hospital, instead of returning to their homes.
Being in a skilled nursing facility increased a person’s likelihood of eventually returning to the hospital by 50 percent, compared to heart failure patients who returned home after their hospital stay. Interestingly, the hospital readmissions for these patients were mostly unrelated to their original heart failure diagnosis.
They also found that 40 percent of heart failure patients are indeed admitted to a skilled nursing facility at some point after diagnosed. The average stay at a skilled nursing facility following a hospital visit due to heart failure averages about 144 days.
“We wanted to try to identify ways to improve outcomes for patients released to a skilled nursing facility, as well as potentially for patients overall," said Mayo Clinic cardiologist and senior author Véronique Roger, MD.
Studies are still ongoing to learn more about the underlying causes behind these statistics, but researchers note a key factor in determining a person’s likelihood for returning to the hospital after being in a skilled nursing facility: the person’s ability to “carry on the activities of daily living.”
In the future, Roger and Manemann would like to see an increase in patient-doctor conversations about what is best for each individual patient, increased mobility for heart failure patients in skilled nursing facilities, and more patients returning home and staying home after their stay in a skilled nursing facility. "Most importantly, we'd like to see healthier individuals able to consistently participate in life activities,” Roger explained.
Sources: National Heart, Lung, and Blood Institute, Mayo Clinic


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Iams Pet Food Recall - July 31, 2010
Welcome to East Maryland Animal Hospital
Call us today! (602) 279-7366
East Maryland Animal Hospital is an AAHA Accredited Animal Hospital in Phoenix and is committed to your pet's health and well being. East Maryland Animal Hospital excels in pet care and progressive veterinary medicine.
Our services and facilities are designed to assist in routine preventive care for young, healthy pets, early detection and treatment of disease as your pet ages, and complete veterinary medical and pet surgical care as necessary during his or her lifetime.
The doctors and staff at East Maryland Animal Hospital have provided Phoenix compassionate veterinary care and pet services year after year, making us the animal clinic of choice for pet owners in and around the Phoenix community.
East Maryland Animal Hospital is a full-service animal hospital whose mission is to provide the highest standard of veterinary care for pets. We genuinely care about your pets and all animals! Our staff is passionate about veterinary medicine and are extremely well trained. We strive to provide professional, affordable, and advanced veterinary services. At East Maryland Animal Hospital, you will walk into a calm, welcoming, and friendly environment every visit, so that the experience is as comfortable as possible for you and your pet.
East Maryland Animal Hospital offers the Phoenix community medical, surgical, and dental services for dogs and cats. We also have an in-house pharmacy with access to specialists, making our veterinary facility a one stop shop for your pet's health and medical needs. We also offer boarding for our canine and feline patients. If you are new to our website, please browse around to learn about our facility and to read interesting pet articles and watch groundbreaking pet videos. Click on the email us link below to ask us a question or to submit feedback. For directions to our office see our contact us page. To receive free veterinary care articles, please subscribe to our newsletter.
Remember, at East Maryland Animal Hospital, your pets are our family!
East Maryland Animal Hospital
Bloat & Gastric Torsion
Gastric Dilation Volvulus (GDV)
Ruptured Anterior Cruciate Ligament (ACL)
Vertigo or Old Dog Vestibular Syndrome
Feline Retro Viruses
High Blood Pressure in Dogs
Online Games & Quizzes
Printable Games & Puzzles
Wellness Coloring Book

domain: pet


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Takashi Miike has spent the last quarter of a century making a LOT of movies. And, in between 1999 and 2002 (approximately), his profile was considerably raised in America and Europe with a selection of unforgettable, and astonishing, works. Films such as Audition (still perhaps his finest hour, for me anyway), Ichi The Killer, Visitor Q, The Happiness Of The Katakuris, and the Dead Or Alive trilogy. Miike was clearly someone worth watching, even if he often placed scenes in his movies that were tough to watch.
Dead Or Alive, at its core, is a very basic film about warring criminal factions and the cop trying to clean things up. There’s a large cast of supporting players, and a number of disturbing vignettes, but the focus ends up on a gangster named Ryuuichi (Riki Takeuchi) and the man who ends up undoing his plans (Sho Aikawa, as Detective Jojima). These two men move through a narrative that allows them to show the shading of their character before finally attempting to paint them as opposing black and white pieces in a winner-take-all endgame.
To call the opening 5+ minute opening sequence of Dead Or Alive blistering is pretty accurate. But anyone who has yet to see the film should be made aware that this is REALLY blistering. It’s an audio-visual assault on your senses, and I’m not using that phrase to be hyperbolic. You get gunfire, dancing, sodomy, drug deals, arterial spray, one hell of a long line of cocaine being snorted, a rocking track overlaying everything, and lots of noodles. The entire sequence sets up the tone of the film, although viewers will undoubtedly breathe a huge sigh of relief when Miike starts to slow things down to a more bearable pace.
Of course, the slowing down of the pace of the movie also means that the unpleasantness, when it occurs, is onscreen for longer. Whether it’s a maker of pornography trying to set up a very twisted scene for a niche market or a drugged-out woman lying around in a small pool full of . . . . . . . well, I’ll let you see for yourself. Even the hardiest of viewers may find their stomach churning on occasion.
And while you could make the valid point that so much of what unfolds here is pointlessly shocking just for the sake of it, you could also argue that Miike, and/or writer Ichiro Ryu, is deliberately railing against a cinematic tradition of cool Japanese killers. Handsome leading men who order clean, swift murders, and who act within a strict code of honour. I may be reading too much into things, and Miike has made films with his fair share of cool killers too, but it almost feels as if this movie deliberately forces viewers to look into the cesspool that violent crime can inhabit. By exaggerating things, by making moments so repugnant that you can almost smell something rotten while the film is running, Miike seems to be using the material to teach us all a lesson about glamorising a lifestyle most of us will hopefully never see outside the edges of a movie screen.
Order the trilogy here.


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What you will be doing
Are you learning Spanish or are a Spanish speaking person? Join our classes on Saturdays. You can have a good sweat whilst practising your Spanish, it’s a win-win!
Classes are super fun and dynamic. I use music and equipment such as fitness a ladder and cones. It's well-balanced, we have a strength part and a cardio part. I change the exercises all the time so it’s fun and you'll see time flies!
We meet right next to the lake in the relaxed lakeside park with open greens.
This class takes place on multiple dates, view all available dates.
All classes with no client bookings get removed from the platform 12 hours before the start-time.


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Published on May 16th, 2015 | by Richard Boom
Prince Pangur Ban the Fluffy the Collected Series
On Dec 31st, 2011 a little furry bundle of joy was brought off a Delta flight and into the lives of Holly Golightly and Jim Balent. They already had his name picked out from an animated film that Holly fell in love with, Pangur Ban! He was the first kitten Holly truly ever raised. But soon they noticed he wasn’t like any other cat that they’ve known. Pangur was clownish, affectionate, personable, and a big chicken- he was a character and Holly felt compelled to draw his antics!
So artist-creator Holly Golightly shared on her webcomic page what life with this wonderful, silly puff of fluff added to their lives. Now, with support of fans, she would love to collect all those comic strips she did from 2011 to 2015 and even create a few NEW ones. This will become a comicbook size, 128 page, full color perfect bound paperback!
On top of all that, Holly is excited to say that Ingrid King, Cat guru, award winning writer & Pangur’s Furry Godmother, is writing the foreword for the Pangur Ban book!


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June 30, 2010
It seems that the hotter it gets here in Montreal, the less we feel like writing about all the great food we’re making at home. And I’m afraid that problem won’t be solved in the near future…we are soon off to visit Iles-de-la-Madeleine, about to stuff our face with lobster, mussels, scallops and clams. We haven’t left on a vacation in a few years, and haven’t smelled the ocean air in even longer, so this is an exiting adventure we’re really looking forward to. We’ll come back with plenty of lobster tales (pun so obviously intended!).
But for now, here’s a quick breakfast Soli whipped up one day. If you have the makings for a traditional eggs ‘n bacon breakfast, as well as some puff pastry, then this is a snap to make, and is amazingly good. A good breakfast tart is a wonderful thing to wake up to!
For this breakfast tart, we used some quality bacon, fiddleheads, mushroom, cheese and eggs. The end result was perfectly cooked eggs, slightly bitter fiddleheads, creamy goat cheese and sauteed mushrooms atop a flaky puff pastry crust. This recipe is extremely versatile though; substitute any ingredient with your own preference.
Could breakfast get any better? Oh! Yes, it can. Drizzle with maple syrup when you’re done and it’s ready to eat.
Breakfast Tart with Fiddleheads, Mushrooms, Bacon and Cheese
adapted from Yum Sugar
1 sheet puff pastry dough
1 egg, lightly beaten with 1 tsp. water
4 oz. cheese (we used a decadent goat cheese)
Salt and freshly ground pepper, to taste
8 bacon slices, cooked until crisp
1 tbsp butter
1 cup fiddleheads
1 cup sliced mushrooms
1. Thaw the puff pastry dough according to the package instructions.
2. Preheat an oven to 425°F. Lightly grease a baking sheet.
3. On lightly floured surface, roll out the puff pastry to 1/4-inch thickness and cut into a 10-by-8-inch rectangle. Place the pastry on the prepared baking sheet. Using a paring knife, score a border 1/2 inch in from the edge of the pastry. Using a fork, prick the center of the pastry. Brush the border with the egg wash and refrigerate for 15 minutes.
4. Saute fiddleheads and mushrooms in the butter until soft.
5. Place the toppings (bacon, fiddleheads, mushrooms, goat cheese) on the tart crust. Bake the tart for 14 minutes, rotating the baking sheet halfway through baking.
6. Remove the baking sheet from the oven and place it on a level heatproof surface. Using a fork, prick any large air pockets in the pastry. Crack the eggs onto the tart, spacing them 2 inches apart. Bake until the egg whites are set and the yolks are still soft, 7 to 10 minutes.
6. Transfer the tart to a platter and serve immediately.
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Chalet Bastidons (Sleeps 12)
Chalet Bastidons is located in the Chenus area of Courchevel 1850 and offers the very heights of luxury alpine style. This 780 square metre property is spread over 5 floors (all served by an internal elevator) and raises the bar of luxury chalets yet further. Finished to the best standards and combining French interior chic with the latest in modern technology Chalet Bastidons offers an exceptional alpine experience.
The main entrance, large living room, dining room and kitchen are on the top floor of the chalet along with a large terrace which gives easterly views (great for the morning sun) across the centre of Courchevel 1850. Below this level are two floors of bedrooms - one floor with two bedrooms (including the master double) and the other floor of three bedrooms. Level -3 has the 6th bedroom and also the cinema room, games room, wine cellar, garage and ski and boot room. The lowest floor is dedicated to the amazing spa with its swimming pool, sauna, Jacuzzi, treatment room, gym, relax area and bar.
The edge of the piste is less than one minute's walk away which means that it's almost possible to ski from and back to the chalet's door. For those that like to sample the best of Courchevel's shopping the centre of the resort is less than 400 metres (4 minutes' walk) from the chalet.
Chalet Bastidons offers secluded luxury, lots of space, great views and a first rate spa. Combine this with the highest quality of staff and in-resort concierge services and you have a chalet that surpasses pretty much any other.
If you would like to view other chalets in Courchevel 1850 please use this link to view our Courchevel 1850 chalet search engine page. From here there is a link to all the other chalet properties we feature in this famous Three Valleys ski resort.
- Under 100 metres
- 200 - 400 metres
- Fully ensuite
- No child care available
- Spa: sauna, gym, steam room, indoor Jacuzzi and bar area.
- Swimming pool (8.45m x 2.80m) and outdoor hot tub.
- Play Station, DVD player and Apple TV.
- All bedrooms with iPod dock, TV and DVD player.
- Office with 2 PCs, printer and TV. Lift serving all floors.
- Garage for 2 cars. Wine cellar. Cinema room, Laundry.
- Level 0:
- Entrance, living room, dining room, kitchen. Large terrace
- Level -1:
- Room 1: double with dressing area. En-suite bath and wc. Terrace
- Room 2: master double, lounge, dressing. Bath, shower & wc. Terrace
- Level -2:
- Room 3: double with dressing area. En-suite shower & wc. Terrace
- Room 4: double with dressing area. En-suite shower & wc. Terrace
- Room 5: double with en-suite bathroom. Terrace
- Terrace with outdoor Jacuzzi
- Level -3:
- Cinema, games room, wine cellar, garage, laundry and ski room
- Room 6: double with dressing area. En-suite shower and wc
- Level -4
- Spa area: pool, gym, indoor hot tub, steam room, sauna & showers
- Treatment room and relax area with bar
- Welcome at the chalet with champagne and gourmet basket
- Half Board services of private chef and hostess for breakfast, and lunch or dinner (cost of food & drink paid extra)
- In resort chauffeur service from 9am to 9pm (or 8am to 8am if you prefer)
- Daily cleaning and evening turn down service (times on rental contract)
- House linen, towels, slippers and bathroom toiletries from Clarins. Hair dryer and safe in each bedroom
- Use of the chalet's office between 9am and 7.30pm
- DVDs available on request
- Cards and board games available on request
- Alpine Answers CONCIERGE SERVICE - assistance with booking lessons, equipment hire & travel
The information below refers to the travel options that can be provided by the tour operator as part of a ‘package’. If the tour operator does not offer the travel option of your choice we may well be able to buy it in for you at a supplement. Please speak to one of our sales consultants for further advice and help with regards travel to and from your chosen resort.
- No travel included
|Standard Price||Current Price||Saving||Beds||Flights||Updated|
|15 December 2018||£4,836||Fully Booked|
|22 December 2018||£6,250||Fully Booked|
|29 December 2018||£11,533||Fully Booked|
|05 January 2019||£7,440||Fully Booked|
|12 January 2019||£4,836||Fully Booked|
|19 January 2019||£4,836||Fully Booked|
|26 January 2019||£4,836||Fully Booked|
|02 February 2019||£4,836||Fully Booked|
|09 February 2019||£6,696||Fully Booked|
|16 February 2019||£6,696||Fully Booked|
|23 February 2019||£6,696||Fully Booked|
|02 March 2019||£6,696||£6,696||-||12||NO||11-Feb||Enquire Now|
|09 March 2019||£5,952||£5,952||-||12||NO||11-Feb||Enquire Now|
|16 March 2019||£5,952||Fully Booked|
|23 March 2019||£5,952||£5,952||-||12||NO||11-Feb||Enquire Now|
|30 March 2019||£5,952||£5,952||-||12||NO||11-Feb||Enquire Now|
|06 April 2019||£4,836||£4,836||-||12||NO||11-Feb||Enquire Now|
|13 April 2019||£4,836||£4,836||-||12||NO||11-Feb||Enquire Now|
Prices per person for 7 nights (based on two people sharing a bedroom). Please note the ‘flights’ column above shows the UK airports that may be used (subject to availability) when the property is booked as a ‘package’ (flights, transfers and accommodation purchased as one ATOL protected bundle) as offered by the respective tour operator.
Prices and availability are subject to change therefore the price of your holiday can only be confirmed at time of booking. Bookings are subject to the relevant tour operator’s terms and conditions. Supplements for rooms, flights, transfers, last minute ticket delivery and other tour operator charges may apply. Please contact our team for a full price. If you pay with credit card a 2% card fee will apply.
- Cable Car
- Chair lift
- Drag lift


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I make Lost Domain entirely by myself, and am so grateful for the community I grew. I also work on the art team for God Game on Voyce.me, a featured comic :)
A Brother's Story (H) (COMPLETED)
Download WEBTOON now!
ⓒ WEBTOON Entertainment Inc.


Carson High's Caydee Farnworth celebrates on third base after hitting a walk-off to right field Saturday afternoon to beat Douglas in the regular-season finale.
Photo by Ron Harpin.
Carson High and Douglas softball played nine back-and-forth innings Saturday afternoon to close out the regular season.
With two runners on and two outs in a 1-0 count in the bottom of the ninth, Carson High’s Caydee Farnworth drove a ball into the outfield, which caught the breeze and dropped a few feet inside fair territory.
The double brought Amberlee Ketten around to score and ends the 2021 spring regular season with a walk-off win for the Senators.
“You wouldn’t expect anything but that against your rival,” said Carson High head coach Carlos Mendeguia. “As an athlete, you want to be at-bat to make that happen and Caydee Farnworth did an outstanding job.”
Farnworth ended her trot around the bases on third where she was mobbed by teammates in celebration.
It was Farnworth’s only base hit of the game, but the junior also threw all nine innings in the circle for Carson.
Farnworth recorded nine punch outs while allowing three earned runs and surrendering three walks.
She threw 99 strikes on 154 total pitches.
In the second inning, senior Kedre Luschar hit her seventh home run in the last 15 days to give Carson a 3-1 lead.
Carson will head into regional play on Tuesday as the No. 4 seed, giving the Senators a home contest against No. 5 McQueen.
“It’s won and lost sometimes on that mound and we are confident in Caydee,” said Mendeguia. “She’s riding high ride now and we are going to ride her as far as she can take us.”
The Senators have beaten McQueen 7-3 and 14-2 this season.
Douglas secured the No. 3 seed prior to Saturday’s contest and will take on No. 6 Reno (5-11) Tuesday.
“We have to have a short memory,” said Douglas high head coach John Glover of the upcoming postseason.
The Tigers have taken care of Reno by scores of 12-0 and 16-2 in their two meetings this year.
Douglas climbs back
Down 4-1 in the sixth, Mehaila Pete helped the Tigers get right back into things with a bloop single to right field.
The base hit brought in two runs before Eva McNinch used a RBI sacrifice fly to left to knot the game at 4-4.
“They have a lot of fight in them,” said Douglas high softball coach John Glover. “We just didn’t execute defensively.”
The Tigers made three errors defensively, but got a quality outing from Talia Tretton in the circle who fanned 15 Carson batters in 8 2/3 innings of work.
Douglas had runners on base in the eighth and ninth innings, but couldn’t secure a timely hit to bring them around.
The win for the Senators mean the two squads split the season series after Douglas won the season-opener 6-1 in Minden.


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Massive Disneyland Attraction Database
Below: Huey's House, a favorite attraction of Captain Hook
April 4, 1990
Avg. queue length:
Walk through Huey's house, lose yourself in his laundry, and throw your kid in his sauna.
- If you are in a hurry, you may want to tell the kids that this attraction is broken.
Policies and Information
- You must be at least as tall as allowable to enjoy this .
- Artistically impaired guests may ask a cast member for an assistive listening device.
- Guests may get wet on this attraction.
- This attraction closes at dusk.
- The top of Huey's House can be viewed from as far away as Mississippi.
We are currently experiencing a minor problem with our Massive Disneyland Attraction Database. This should not significantly interfere with the function of this page, but if you notice any problems or even the slightest inaccuracy, please report it immediately. Thank you for your courtesy.


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I'm just a weird French girl.
I tried to make an edit for the #55yearsofdoctorwho (Sorry if it's not good, I'm new at this but I wanted to give it a shot) So happy birthday to this amazing show which brought us all so much :two_hearts: :birthday: :tada:
I don't know what I'm doing but oh well... Here, have some weird edits I just made :joy:
I made a second entry for the #WeeklyWhovian and it may not be the last because I really like making these (even if I'm not really good at that :sweat_smile: )
That's probably not the best but I really enjoyed making it and I may do some others :blush:
I usually don't do challenges, but the #ArtOfCreation seems really interesting (and doesn't include drawing :stuck_out_tongue_winking_eye: ) I chose Terry Nation because I think he is the one who had the biggest impact on the show. Terry Nation is the man who created the most iconic villains of Doctor Who : The Dal...
I'm relatively new to Amino and I've never rp so I would like help to know how to make an OC and how to rp please can someone help me ?!
So recently, I was on YouTube searching for Doctor Who videos and I found President Romana. I think she does incredible songs who are, in my opinion, as good as Chameleon Circuit's songs. I haven't listened to all her songs yet but I think these are my favourites (the lyrics are in the descriptions ...
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|Alternative names||The Mount Hopkins Observatory|
|Named after||Fred Lawrence Whipple|
|Observatory code||G91, 696|
|Location||Mount Hopkins, Amado, Mount Hopkins, US|
|Coordinates||31°40′52″N110°52′41″W / 31.6811°N 110.878°W Coordinates: 31°40′52″N110°52′41″W / 31.6811°N 110.878°W|
|Altitude||2,606 m (8,550 ft)|
|Related media on Commons|
The Fred Lawrence Whipple Observatory is an American astronomical observatory owned and operated by the Smithsonian Astrophysical Observatory (SAO); it is their largest field installation outside of their main site in Cambridge, Massachusetts. It is located near Amado, Arizona on the summit, a ridge and at the foot of Mount Hopkins.
Research activities include imaging and spectroscopy of extragalactic, stellar, solar system and extra-solar bodies, as well as gamma-ray and cosmic-ray astronomy.
In 1966, roadwork began on the current site with funding granted for the Smithsonian Mt. Hopkins Observatory. The Whipple 10-meter gamma-ray telescope was constructed in 1968.
Formerly known as The Mount Hopkins Observatory, the observatory was renamed in late 1981 in honor of Fred Lawrence Whipple, noted planetary expert, space science pioneer, and director emeritus of SAO, under whose leadership the Arizona facility was established.
Whipple observatory hosts the MMT Observatory, which is jointly run by SAO and the University of Arizona and houses a 6.5-meter telescope. The observatory also has 1.5- and 1.2-meter reflectors and a second 1.3-meter reflector named PAIRITEL (Peters Automated IR Imaging Telescope, ex-2MASS ). Also on site is the HATNet (Hungarian-made Automated Telescope) network, the MEarth Project, and four 0.7-meter telescopes of the automated Miniature Exoplanet Radial Velocity Array (MINERVA).
The observatory is known for its pioneering work in ground-based gamma-ray astronomy through the development of the Imaging Atmospheric Cherenkov Technique (IACT) with the Whipple 10-meter Telescope during the early 1980s. The Whipple 10-meter is currently preparing to be decommissioned after forty years of service.
In April 2007, VERITAS (a system of 4 IACT telescopes with 12-meter reflectors) started full operations at the FLWO basecamp. Subsequently, in September 2009, after a 4-month effort, one of the telescopes was moved to a new position, making the array symmetric and increasing its sensitivity.
The Kitt Peak National Observatory (KPNO) is a United States astronomical observatory located on Kitt Peak of the Quinlan Mountains in the Arizona-Sonoran Desert on the Tohono Oʼodham Nation, 88 kilometers (55 mi) west-southwest of Tucson, Arizona. With more than twenty optical and two radio telescopes, it is one of the largest gatherings of astronomical instruments in the Earth's northern hemisphere.
The Mount Wilson Observatory (MWO) is an astronomical observatory in Los Angeles County, California, United States. The MWO is located on Mount Wilson, a 1,740-meter (5,710-foot) peak in the San Gabriel Mountains near Pasadena, northeast of Los Angeles.
Steward Observatory is the research arm of the Department of Astronomy at the University of Arizona (UArizona). Its offices are located on the UArizona campus in Tucson, Arizona (US). Established in 1916, the first telescope and building were formally dedicated on April 23, 1923. It now operates, or is a partner in telescopes at five mountain-top locations in Arizona, one in New Mexico, one in Hawaii, and one in Chile. It has provided instruments for three different space telescopes and numerous terrestrial ones. Steward also has one of the few facilities in the world that can cast and figure the very large primary mirrors used in telescopes built in the early 21st century.
The Harvard College Observatory (HCO) is an institution managing a complex of buildings and multiple instruments used for astronomical research by the Harvard University Department of Astronomy. It is located in Cambridge, Massachusetts, United States, and was founded in 1839. With the Smithsonian Astrophysical Observatory, it forms part of the Center for Astrophysics | Harvard & Smithsonian.
The Cerro Tololo Inter-American Observatory (CTIO) is an astronomical observatory located on Cerro Tololo in the Coquimbo Region of northern Chile, with additional facilities located on Cerro Pachón about 10 kilometres (6.2 mi) to the southeast. It is approximately 80 kilometres (50 mi) east of La Serena, where support facilities are located. The site was identified by a team of scientists from Chile and the United States in 1959, and it was selected in 1962. Construction began in 1963 and regular astronomical observations commenced in 1965. Construction of large buildings on Cerro Tololo ended with the completion of the Víctor Blanco Telescope in 1974, but smaller facilities have been built since then. Cerro Pachón is still under development, with two large telescopes inaugurated since 2000, and one in the early stages of construction
The Smithsonian Astrophysical Observatory (SAO) is a research institute of the Smithsonian Institution, concentrating on astrophysical studies including galactic and extragalactic astronomy, cosmology, solar, earth and planetary sciences, theory and instrumentation, using observations at wavelengths from the highest energy gamma rays to the radio, along with gravitational waves. Established in Washington, D.C., in 1890, the SAO moved its headquarters in 1955 to Cambridge, Massachusetts, where its research is a collaboration with the Harvard College Observatory (HCO) and the Harvard University Department of Astronomy. In 1973, the Smithsonian and Harvard formalized the collaboration as the Center for Astrophysics | Harvard & Smithsonian (CfA) under a single Director.
The Center for Astrophysics | Harvard & Smithsonian (CfA), alternatively called the Harvard–Smithsonian Center for Astrophysics, is an astrophysics research institute jointly operated by the Harvard College Observatory and Smithsonian Astrophysical Observatory. Founded in 1973 and headquartered in Cambridge, Massachusetts, the CfA leads a broad program of research in astronomy, astrophysics, Earth and space sciences, as well as science education. The CfA either leads or participates in the development and operations of more than fifteen ground- and space-based astronomical research observatories across the electromagnetic spectrum, including the forthcoming Giant Magellan Telescope (GMT) and the Chandra X-ray Observatory, one of NASA's Great Observatories.
Roque de los Muchachos Observatory is an astronomical observatory located in the municipality of Garafía on the island of La Palma in the Canary Islands, Spain. The observatory site is operated by the Instituto de Astrofísica de Canarias, based on nearby Tenerife. ORM is part of the European Northern Observatory.
The Indian Astronomical Observatory (IAO) is a high-altitude astronomy station located in Hanle, India and operated by the Indian Institute of Astrophysics. Situated in the Western Himalayas at an elevation of 4,500 meters (14,764 ft), the IAO is one of the world's highest located sites for optical, infrared and gamma-ray telescopes. It is currently the tenth highest optical telescope in the world. It is India's first dark-sky preserve.
The MMT Observatory (MMTO) is an astronomical observatory on the site of Fred Lawrence Whipple Observatory. The Whipple observatory complex is located on Mount Hopkins, Arizona, US in the Santa Rita Mountains. The observatory is operated by the University of Arizona and the Smithsonian Institution, and has a visitor center in nearby Amado, Arizona. The MMTO is the home of the MMT, which has a primary mirror 6.5 m in diameter. The name comes from the six smaller mirrors originally used before the single primary mirror was installed in 1998. The primary mirror has a special lightweight honeycomb design made by the University of Arizona's Steward Observatory Mirror Laboratory. The MMT is housed in a building which allows the walls and roof around the telescope to be completely rolled back, allowing it to cool down very quickly in order to improve observation.
IACT stands for Imaging AtmosphericCherenkov Telescope or Technique. It is a device or method to detect very-high-energy gamma ray photons in the photon energy range of 50 GeV to 50 TeV.
Xinglong Station is an observatory situated south of the main peak of the Yan Mountains in Xinglong County, Chengde, Hebei province, China. Installed are seven telescopes: a Mark-III photoelectric astrolabe; a 60 cm reflector; an 85 cm reflector; a 60/90 cm Schmidt telescope; a 1.26-meter infrared telescope; and a 2.16-meter telescope. The most recent telescope is the 4m LAMOST. As of 2014 the observatory installed a 5.2-meter telescope as part of their Gamma-ray astronomy program, known colloquially as Sām Tām for its aggressive focal length. It is a popular tourist site.
VERITAS is a major ground-based gamma-ray observatory with an array of four 12 meter optical reflectors for gamma-ray astronomy in the GeV – TeV photon energy range. VERITAS uses the Imaging Atmospheric Cherenkov Telescope technique to observe gamma rays that cause particle showers in Earth's atmosphere that are known as extensive air showers. The VERITAS array is located at the Fred Lawrence Whipple Observatory, in southern Arizona, United States. The VERITAS reflector design is similar to the earlier Whipple 10-meter gamma-ray telescope, located at the same site, but is larger in size and has a longer focal length for better control of optical aberrations. VERITAS consists of an array of imaging telescopes deployed to view atmospheric Cherenkov showers from multiple locations to give the highest sensitivity in the 100 GeV – 10 TeV band. This very high energy observatory, completed in 2007, effectively complements the Large Area Telescope (LAT) of the Fermi Gamma-ray Space Telescope due to its larger collection area as well as coverage in a higher energy band.
The Lowell Discovery Telescope (LDT), formerly the Discovery Channel Telescope (DCT), is a 4.3 m (170 in) aperture telescope owned and operated by Lowell Observatory. The LDT was built at a dark sky site in the Coconino National Forest near Happy Jack, Arizona. Happy Jack is located at an elevation of 2,360 m (7,740 ft) and is approximately 65 km (40 mi) south-south-east of Flagstaff. The project was initially a partnership between Discovery Communications and Lowell Observatory. The research partnerships have been extended to include Boston University, The University of Maryland, The University of Toledo, and Northern Arizona University. The telescope cost $53 million. It significantly augments Lowell Observatory's observational capability and enables pioneering studies in a number of important research areas.
Mount Burnett Observatory is an astronomical observatory in Mount Burnett, Victoria, Australia.
Catalina Station (CS), also known as Steward Observatory Catalina Station, is an astronomical observing facility located on Mount Bigelow in the Santa Catalina Mountains approximately 29 kilometers (18 mi) northeast of Tucson, Arizona. The site in the Coronado National Forest is used with special permission from the United States Forest Service by the Steward Observatory of the University of Arizona.
Major Atmospheric Cerenkov Experiment Telescope (MACE) is an Imaging Atmospheric Cerenkov telescope (IACT) located near Hanle, Ladakh, India. It is the highest and second largest Cerenkov telescope in the world. It was built by Electronics Corporation of India, Hyderabad, for the Bhabha Atomic Research Centre and was assembled at the campus of Indian Astronomical Observatory at Hanle. It was originally scheduled to become operational by 2016, but plans were pushed back to begin operations in 2020. It will be remotely operated and will run on solar power.
Giovanni Fazio is an American physicist at Center for Astrophysics | Harvard & Smithsonian. He is an astrophysicist who has initiated and participated in multiple observation programs.


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Thursday, Nov. 28: Zumba Instructor Vicki Toole (also a Lakes Region Weekly columnist) is offering a free Zumba class on Thanksgiving Day morning. Pop the bird in the oven and then come do some pre-feast calorie burning (just don’t literally burn the Turkey!) Class starts at 9 a.m. at the Bridgton Old Town Hall. For more information, contact Vicki at 939-2436 or email her at firstname.lastname@example.org.
Friday, Nov. 29: The Windham Kiwanis Club starts their 38th season selling Christmas trees in front of Aubuchon Hardware on Route 302 in North Windham. Kiwanis members will staff the nonprofit stand through the third week of December weekdays 2:30-5 p.m. and weekends 10 a.m.-5 p.m. All trees are $25. All proceeds are used for community programs.
Sunday, Dec. 1: A tree lighting at 5 p.m. is sponsored by the Raymond Lions Club in conjunction with the Raymond Village Library and begins the holiday season each year in Raymond. All are invited. There will be carolers from the Raymond schools to entertain and refreshments will be served. There will be a special story time beginning at 4:30 p.m., presented by Lisa Davison, youth services assistant.
Thursday, Dec. 5: At 7 p.m., State Sen. Gary Plummer, and state Reps. Tom Tyler and Jane Pringle are sponsoring a community forum on the Affordable Care Act at the Windham Town Council chambers in town hall. The presentation and question-and-answer session will be led by Carol Zechman from CarePartners and the MedAccess program. Zechman and her team are Certified Application Counselors who can answer questions about the ACA and can also help people sign up at their offices in Portland.
Dec. 5: Lyn Sudlow, author of “A Vast Army of Women: Maine’s Uncounted Forces in the American Civil War,” will share some stories from her book at 7 p.m. at the North Gorham Public Library on 2 Standish Neck Road. Co-sponsored by the library and the Gorham Arts Alliance with a grant from the Maine Humanities Council, the program is one of a series of public events commemorating Maine’s role in the Civil War. For more information call 314-0584 or the library at 892-2575.
Saturday, Dec. 7: Books, baked goods, and some crafts will be for sale at the North Gorham Public Library from 9 a.m. to 2 p.m. There will be a selection of good used books, primarily fiction. Holiday baked goods will be available from the UCC church guild and a few local crafters will have their wares for sale. The library is located at the corner of Standish Neck Road and North Gorham Road. For more information, call 892-2575.
Sunday, Dec. 8: A Bake and Holiday Gift Basket Sale takes place at the Raymond Village Library, 3 Meadow Road, Raymond, beginning at 10 a.m. until closing at 5 pm. Christmas cookies, pies, breads and all kinds of yummy treats for holiday giving and enjoyment. Come early for best selection.
Dec. 8: Join Casco Village Church UCC, 941 Meadow Road (Route 121), in Casco, at 4 p.m. when the choir under the direction of Eugene Long with accompanist Evan Cuddy performs classical and contemporary musical selections for your holiday enjoyment. Admission is free. There will be a free will offering, and refreshments afterward in the Great Hall.

domain: library


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Kriadex Clonazepam 2mg is an antiepileptic drug from the group of benzodiazepine derivatives. It has a pronounced anticonvulsant, as well as central muscle relaxant, anxiolytic, sedative and hypnotic effects.
This medicine is prescribed for a specific person. It cannot be passed on to others. The drug can harm another person, even if their symptoms are the same.
Generic Name: Clonazepam.
Brand Name: Kriadex.


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P349 Muscle mitochondrial function and N+/K+ -ATPase activity are unaffected by sepsis in pigs
M Von Seth, L Hillered, A Otterbeck, K Hanslin, A Larsson, J Sjölin, M Lipcsey
Uppsala University, Uppsala, Sweden
Imbalance in cellular energetics has been suggested to be an important mechanism for organ failure in sepsis and septic shock. We hypothesized that such energy imbalance would either be caused by metabolic changes leading to decreased energy production or by increased energy consumption. Thus, we set out to investigate if mitochondrial dysfunction or decreased energy consumption alters cellular metabolism in muscle tissue in experimental sepsis.
We submitted anesthetized piglets to sepsis (n = 12) or placebo (n = 4) and monitored them for 3 hours. Plasma lactate and markers of organ failure were measured hourly, as was muscle metabolism by microdialysis. Energy consumption was intervened locally by infusing ouabain through one microdialysis catheter to block major energy expenditure of the cells, by inhibiting the major energy consuming enzyme, N+/K + -ATPase. Similarly, energy production was blocked infusing sodium cyanide (NaCN), in a different region, to block the cytochrome oxidase in muscle tissue mitochondria.
All animals submitted to sepsis fulfilled sepsis criteria as defined in Sepsis-3, whereas no animals in the placebo group did. Muscle glucose decreased during sepsis independently of N+/K + -ATPase or cytochrome oxidase blockade. Muscle lactate did not increase during sepsis in naïve metabolism. However, during cytochrome oxidase blockade, there was an increase in muscle lactate that was further accentuated during sepsis. Muscle pyruvate did not decrease during sepsis in naïve metabolism. During cytochrome oxidase blockade, there was a decrease in muscle pyruvate, independently of sepsis. Lactate to pyruvate ratio increased during sepsis and was further accentuated during cytochrome oxidase blockade. Muscle glycerol increased during sepsis and decreased slightly without sepsis regardless of N+/K + -ATPase or cytochrome oxidase blocking. There were no significant changes in muscle glutamate or urea during sepsis in absence/presence of N+/K + -ATPase or cytochrome oxidase blockade.
These results indicate increased metabolism of energy substrates in muscle tissue in experimental sepsis. Our results do not indicate presence of energy depletion or mitochondrial dysfunction in muscle and should similar physiologic situation be present in other tissues, other mechanisms of organ failure must be considered.