text:
pH Regulation During Exercise
We all know that we need oxygen. It is breathed in through our lungs then “magically” transported to the blood stream where it is combined with fuel in the cells. Ultimately this gives us energy to fulfill our busy lives. A resting adult uses about 250 mL of pure oxygen pure minute, but only 1.5 percent of it is dissolved directly in the blood plasma. During exercise and work, the body uses more. The rest is transported by the hemoglobin in a metal complex called heme. Heme consists of iron complexes which transport oxygen to the cells and tissues. Through complex signaling the oxygen dock and undocks from the heme. Polypeptide chains are formed from amino acids and the metal complexes. In hemoglobin, the hydrogen-bonding interaction occurs between the H of an -NH group and the O of a -CO group of the polypeptide backbone chain. You’ll notice that these molecules are alkaline, they have a negative charge. So all interactions in the blood must help it return to its alkaline 7.365 to 7.425 range.
In 1904 Christian Bohn discovered that it was the increase in CO2 and H+ ions in the tissues that triggered the release of oxygen by the hemoglobin to which tissues required it the most. Known as the Bohr effect, it shows how the body’s blood gas exchange mechanism works. The oxygenated blood is pumped from the heart to the body cells because these tissues require oxygen to move particularly during exercise. The more movement and exercise that happens, generates more CO2 and H+ stimulating the hemoglobin to carry the O2 there and release it where the highest concentrations of CO2 and H+ are. It is necessary for the oxygen to be bound to the hemoglobin until it gets to the oxygen depleted tissues. In the lungs, the reverse effect occurs: high concentrations of O2 cause the release of CO2 from hemoglobin. This is all done through what is called salt bridging. These salt bridges are interactions between positively and negatively charged amino acid residues. There’s that acid/alkaline thing again.
Drink Cerra Water which will enhance athletic performance and endurance by making oxygen more available and bring the body into an alkaline balance.
Guex, N. and Peitsch, M.C. Electrophoresis,1997,18, 2714-2723. (SwissPDB Viewer) URL: HYPERLINK “http://www.expasy.ch/spdbv/mainpage.htm” http://www.expasy.ch/spdbv/mainpage.htm.
Ji, X. et al. “Positive and negative cooperativities at subsequent steps of oxygenation regulate the allosteric behavior of multistate sebacylhemoglobin,” (1996) Biochemistry, 35, 3418. Hemoglobin PDB coordinates, Brookhaven Protein Data Bank.
Kavanaugh, J.S. et al. “High-resolution x-ray study of deoxyhemoglobin Rothschild 37beta trp->arg: a mutation that creates an intersubunit chloride-binding site,” (1992) Biochemistry, 31, 4111. Deoxyhemoglobin PDB coordinates, Brookhaven Protein Data Bank.
Kilmartin, J.V. “Interaction of haemoglobin with protons, CO 2, and 2,3-diphosphoglycerate,” (1976) Br. Med. Bull., 32, 209.
Persistence of Vision Ray Tracer (POV-Ray). URL: HYPERLINK “http://www.povray.org” http://www.povray.org.
Royer Jr., W.E. “High-resolution crystallographic analysis of co-operative dimeric hemoglobin,” J. Mol. Biol., 235, 657. Oxyhemoglobin PDB coordinates, Brookhaven Protein Data Bank.
Stryer, L. Biochemistry, 4th ed. W.H. Freeman and Co., New York, 1995, p.

domain: chemistry


text:
The lewd mayor of Coventry: Suspended, the Tory who propositioned a guest while 'zonked' at an official ball
A Lord Mayor who got drunk at a ball and made lewd sexual comments to a married woman has been suspended from his council.
Andy Matchet was hosting the Lord Mayor's Ball in Coventry last year when he allegedly told a company chief executive repeatedly: 'I'd like to **** you.'
He later blamed his behaviour on excess drink and medication he was taking for a bad back.
Suspended: Coventry mayor Andy Matchet, pictured with his wife Caron at the Lord Mayor's Ball last year, made lewd sexual comments to two colleagues
Mr Matchet, who was wearing his full mayoral chains on the night, also talked about orgasms and divulged that he lost his virginity at 21 because he was 'shy' and did not understand women, it was claimed.
The Tory councillor stood down as Mayor of Coventry in May when his one-year term ended, but there was an ongoing investigation into the incident.
On Monday he was suspended from his position as councillor for three months, after a Standards Committee disciplinary hearing deemed his comments 'prolonged and inappropriate'.
His punishment was yesterday put on hold when he won the right to appeal.
But he will be suspended from the Coventry Conservatives and could face deselection by the party next month.
At the ball last December, the married father of two allegedly told the woman, the 45-year- old chief executive of a voluntary organisation: 'I enjoyed dancing with you, I find you attractive. I'd like to **** you. Am I wrong in saying that?'
She is said to have replied: 'You need to realise that all women are the same once you get their clothes off. The grass isn't always greener, you know. When you're married like you are some other women may seem more exciting than your wife, but we're all the same.'
The Mayor asked the woman whether she would have sex with him
three times, according to a transcript of the alleged incident, seen by
the Mail, which formed part of an official investigation.
The outburst came during a conversation between the then Lord Mayor, the unidentified woman named only as Ms X, and the council's then equality and diversity officer, Laura Slegg.
Councillor Matchet admitted being drunk at the ball but is appealing the decision
The councillor's wife Caron, 47, was sitting two tables away at the ball, held at the Coventry Football Club stadium, the Ricoh Arena.
Mr Matchet, 57, admitted being 'zonked' after downing glasses of red wine and a cocktail of medication for a bad back. He said he remembered nothing of the alleged incident, describing it as an 'other-worldly' experience.
He said: 'I am an extremely argumentative person. It is the sort of comment I would have made as part of an argument about radical feminism.
'I would have said it argumentatively, not invitationally. I'd had several glasses of wine and was on medication because of my bad back, including paracetamol, Codeine, Ibuprofen and dodo tablets, an over-the-counter lowlevel amphetamine.
'I don't remember much of the evening. It's hard to explain
except with a sense of otherworldness. If I said anything that caused
offence to anybody in the circumstances, that is unacceptable and I
would unreservedly apologise.'
He denied he was wearing his mayoral chain at the time of the alleged incident, saying that he had passed it to the chairman of the Freeman's Guild while he danced with some of the 600 guests at the fundraising ball.
Miss Slegg, 27, who knew Mr Matchet from council meetings, lodged a formal complaint after allegedly witnessing the outburst.
Ms X has not complained and has asked to remain anonymous.
Miss Slegg recorded her observations after getting back from the ball to her home in Earlsdon, Coventry - the ward where Mr Matchet is a councillor.
Her notes said: 'Totally inappropriate, abusing position of power, face of council/city. We have a duty to promote gender equality, not sleaze.
'Language unacceptable, beyond flirty behaviour. Was on official duties, not just a night down the pub - even then would be inappropriate.'
Miss Slegg told the Coventry Telegraph this week: 'I don't think he should have been allowed to get away with it.
'As Lord Mayor he was the face of Coventry and representing me as an employee. My concern was it may not have been a one-off.'
A council spokesman confirmed that the sanction against Mr Matchet had been suspended. An appeal hearing is expected next month. Ken
Taylor, leader of the Coventry Conservatives, said: 'In light of the Standards Committee decision on the complaint made against Councillor Matchet, he will be suspended from membership of the Conservative Group and Party.'
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domain: law


text:
Last weekend was the Renegade Craft Fair, for the second time in Los Angeles, but it was my first experience going. It took place outside in a large park north of Chinatown, apparently known as “the cornfield”. Events of all kinds easily go unnoticed in a large city like L.A., and I don’t remember how I learned about this one, but I’m glad I went, it was quite a huge event with over 200 artists!
It’s wonderful to see so many creative people together in one space. With that much to look at I surely missed a ton. While I thought about taking a few snapshots, I was mostly busy trying to collect as many mental pictures as I could for inspiration, but I’ll share here what’s actually in physical form.
It’s kind of funny how the subconscious works, but unknowingly I gravitated to a couple booths that were occupied by Montreal artists. It’s not because it’s my hometown, but I immediately loved these guys’ work. In the one booth above was Sérigraphie Cinq Un Quatre (Alice Jarry and Jason Cantoro), which produces beautiful and unexpected prints with layered photographs and textures. I chatted with the artists for a little while, they’re super nice. I bought two cool prints for my bedroom.
Ah the purses… like nothing I had seen before, I just could not resist. Then I learned they were together with Alice and Jason next door, who generate the graphics printed on the leather. Rachel explained she uses recycled leather for her creations. I did not need more convincing. See the cute purse I bought below.
Another temptation, this tee shirt from Recession Clothing, great colors and shape.
There were too many people in front on that booth to take a good photo of their colorful prints selection, but it’s easy to remedy because they’re on etsy.
As if cupcakes were not cute enough, these edible stickers really add the cherry on the sundae. With a modern flair at that.
It seems the world can never get enough pillows (those are made by Park and Beach), especially when they are this cheerful.
Last picture, I don’t remember what booth I took this at, but this one is to remind me that fabric stretched on a canvas is one option for wall art.

domain: artistic


text:
The Jackass team reunites for another round of mayhem.
The Jackass 4 crew revealed their hesitation about doing the newest installment in the stunt-oriented franchise.
The guys of Jackass are still pushing their bodies to the limit 20 years after the MTV series premiered.
You’ll have to wait a little longer for Tom Cruise’s big screen returns, among various other delays over at Paramount.
Your Daily Blend of Entertainment News
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domain: news


BeatBuddy Guitar Pedal Drum Machine BeatBuddy is the first drum machine in a guitar pedal format that enables full hands-free, creative control of the beat. Musicians can effortlessly insert fills, transition from verse to chorus, add accent hits, throw in drum breaks, and more, to create an unprecedented live drummer effect - all in award-winning, ultra-realistic 24-bit sound. The non-quantized beats, recordings of real drummers, makes BeatBuddy the first drum machine to not sound like a machine. BeatBuddy is packed with features for musicians from all walks of life. A visual display of the beat makes it easy to improve rhythm or play with unfamiliar time signatures. MIDI Sync controls your loopers to make sure they're in time with the beat. Record directly from the BeatBuddy for professional-level drums on your upcoming album. Create gig lists and scroll through your songs, hands-free, during your next performance.
It's the power of a drum machine with the simplicity of a pedal.
- MIDI Sync
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BeatBuddy Dual Footswitch
When you pair the Footswitch+ with the BeatBuddy or BeatBuddy MINI it gives you even more control over the beat. Right out of the box you get the ability to trigger accent hits, pause/unpause the beat, and navigate songs, genre, and tempo. However, when used with the BeatBuddy, you can do even more with the Footswitch+ like setting it to act as the main pedal.
But, it doesn’t stop there! The Footswitch+ is hands down the best multipurpose 2 button footswitch on the market. It’s built like a tank, is more comfortable than a footswitch has any right to be, and offers quiet, momentary switches.
- It lets you add accent hits, pause/unpause the beat, and choose song, genre and BPM, and more when used with the BeatBuddy or BeatBuddy MINI
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- Use the included 1/4″ low profile right-angle TRS stereo cable or substitute it for your own stereo cable
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text:
RC Scale article in "FAA Aviation News"
My office mail today contained the latest FAA Aviation News. Its cover article is titled "All a Matter of Scale", and the cover photo is Claude McCullough adjusting the engine on his giant scale Waco. While e-flight gets only a passing mention, the article is worth the read. Clicking on the above link will take you to the index page, with the cover picture, and a link to the left will take you to the article, complete with photos.
|Category||Thread||Thread Starter||Forum||Replies||Last Post|
|Steve Neu's article in 10/05 SF, "The Good, Bad and the Ugly" LiPos||nadt770||Batteries and Chargers||1||Oct 03, 2005 03:47 PM|
|Scale electric models used in "The Aviator"||Rex A Lott||Scale Kit/Scratch Built||0||Feb 28, 2005 11:38 AM|
|Received my new "Model Aviation" Magazine in the mail yesterday.||Starguard||AMA (Academy of Model Aeronautics)||1||Sep 08, 2004 04:45 PM|
|"Intro to Club Racing" article live in RCPower!||AMCross||Fuel Plane Talk||0||May 13, 2004 03:25 PM|

domain: hobby


text:
Chennai Metro rail services may have been suspended due to lockdown to curb the spread of Covid-19 during the second wave, but trains are being operated twice daily to keep them in good condition.
Officials said two to four trains-each having four cars- are operated across both the corridors covering 45 km early in the morning and late in the evening during the lockdown period. An official said they are operating it based on instructions from the ministry of housing and urban affairs to all metro rail services in the country.
Also, it was the only way to ensure the trains are kept ready for operation when services resume. CMRL operated trains across the corridors daily during the nearly five months of lockdown in 2020, before services were resumed in September 2020. Now, they are following the same procedure for the upkeep of their fleet.
“We cannot keep the trains idle for a long time. Normally, when they are idle for a month, many of its parts like axle bearing and gear box get damaged or turn faulty due to the grease and oil present in it,” an official said.
“Some time ago, Delhi metro kept new trains they procured idle for nearly six months because the line was not ready. Due to the pressure, the bottom edge of the train wheels began to flatten. Though such things happen only if the trains are kept idle for a very long period, we want to ensure our trains are in good condition,” the official said.
At present, two trains each on the up line and down line are operated on two corridors twice a day. They stop at every station just like they would do during regular operations. The staff at every station is present during this operation.
“We also operate the train in the train wash plant at the depot once in three days to clean the exterior. So, trains are running there too,” an official said. “Otherwise the scheduled regular train maintenance work is being undertaken during this period. No additional work is planned,” the official said.


Feds Spotlight Miami As Capital Of COVID-19 And Benefits Fraud
Miami Herald (FL)
A year ago, Congress agreed to spend hundreds of billions of dollars on benefits for small businesses and employees devastated by the coronavirus pandemic.
Of course, the government's handout helped the struggling economy. But it also opened the door for a menagerie of con artists to fleece the federal relief program to get rich quick.
Among them: a South Florida man alleged to have bought a Lamborghini for $318,000 with millions in COVID-19 relief loans; a Broward County tax preparer who purportedly pocketed huge commissions for filing $28 million worth of phony business loan applications; and a former NFL player from Miami accused of stealing people's identities to collect $300,000 in unemployment insurance benefits.
As the nation's No. 1 fraud capital, South Florida led the financial crime wave that followed the passage of the CARES Act, a group of federal law enforcement officials acknowledged Friday. They highlighted dozens of new and old COVID-19 criminal cases to draw attention to the escalating problem. Over the past year, South Florida's federal prosecutors have filed 38 criminal cases with $75 million in fraudulent COVID-19 relief claims — the highest number of any region in the country.
U.S. Attorney Ariana Fajardo Orshan lamented the region's dubious reputation while condemning criminals who steal from the taxpayer-funded relief program at the expense of legitimate businesses and employees desperately trying to stay afloat.
"This is very sad when you have so many Americans in this country who are starving because of the pandemic," Fajardo said during a live news conference at the U.S. Attorney's Office in Miami. "Leave the money for those who need it."
Fajardo — flanked by regional officials with the FBI, IRS, the U.S. Postal inspection Service and other federal agencies — focused on three major programs that have been exploited in the aftermath of last year's adoption of the CARES Act. They are known as the Paycheck Protection Program (PPP), Economic Injury Disaster Loans (EIDL) and Unemployment Insurance.
Here's a trio of new cases cited by authorities:
— Wally Dorlus, 41, a Margate tax preparer and two other South Florida men are charged in a conspiracy to obtain fraudulent PPP loans from the Small Business Administration by using falsified employee, payroll and tax information. According to a criminal complaint, Dorlus received hefty kickbacks in exchange for filing more than 167 fraudulent PPP loan applications worth $28 million. Of those, 33 loans were approved by banks and funded with $5.5 million guaranteed by the SBA.
— Kenbrell Armod Thompkins, 32, a former NFL wide receiver who had played at Miami Northwestern Senior High School, is charged with stealing the identities of numerous Florida residents to obtain fraudulent unemployment insurance benefits totaling $300,000 from the state of California. That state distributed the unemployment benefit funds in the form of debit cards, which were subsequently mailed to addresses associated with Thompkins in Miami and Aventura. Thompkins is accused of withdrawing most of the funds on the debit cards at ATMs in Miami-Dade.
— Kimberly Cleare, 53, of Miami Gardens, is charged with submitting at least 13 nearly identical EIDL applications to the Small Business Administration on behalf of herself and others.
Although South Florida was the focus of Friday's news conference, an IRS official said that the agency is working on 350 criminal cases and open investigations nationwide that involve about $440 million in COVID-19 relief applications filed "fraudulently by greedy criminals." Tyler R. Hatcher, acting special agent of the IRS criminal investigations division in Miami, estimated that half of those phony loan applications — $220 million — were paid out, representing a significant loss to taxpayers. Hatcher said the IRS hopes to recover some of that money.
Despite efforts by banks to scrutinize applicants' COVID-19 loan applications, some false claims slip through because the bankers are not checking the taxpayer history of illegitimate businesses and employees. The root of the problem is that that the government, which guarantees the loans as long as they are used for payroll, rent and other legitimate expenses, pushed the relief money out as quickly as possible to boost the faltering economy.
"Yes, it's not a perfect system," said Fajardo, who resigned from her position as U.S. attorney in South Florida on Friday as part of a routine transition during a change in the presidency last fall. "There is no perfect system."


text:
“What thou lovest well is thy true heritage
What thou lov’st well shall not be reft from thee.”
Ezra Pound Birthplace House
The Ezra Pound House is a rare find, given its age and most famous (some historians might say “infamous”) resident, Ezra Pound (1885-1972). Harsh weather conditions are miserable for historical houses in this climate, but somehow this one has survived. The address is 314 Second Avenue South, Hailey, Idaho. Hailey is a small town in central Idaho.
According to idahoheritage.org, an information hub for the Idaho Heritage Trust:
“The birthplace of poet Ezra Pound built on, added to or moved to its present location by his father, Homer Pound, who came to Hailey by presidential appointment as Register of Mines in 1883. His son, Ezra, born in 1885, was the first child to be christened in Emmanuel Episcopal Church, two blocks away. The house eventually came to be known as the McKercher House after Roberta McKercher, a reporter for the Hailey Times.”
Pound’s poetry can be challenging to understand, unless French and Latin are your strong-points. His career and financial choices are even more difficult to comprehend in that they ultimately placed him in incarceration. But, the landmark house is worth a visit, if just to applaud that the longevity of the house matches the long life of the poet’s work.
Pound was controversial for many reasons but perhaps the most public reason was his outspoken anti-semitism in the era of World War II. Read more here: https://www.newstatesman.com/culture/poetry/2017/02.
Even if you are not a fan of Pound’s writing, you may still appreciate his early support of friend Robert Frost, which helped launch Frost’s career when Frost was at a pivotal point in his life. (See Robert Frost entries on our Florida, New Hampshire and Vermont pages.)
The Ezra Pound Birthplace House is the third stop on our Idaho Author Adventures Trail.

domain: literature


Issued on • Modified
Obama to scale back nuclear weapons strategy
US President Barack Obama plans to place new restrictions on the use of atomic weapons as part of a major US nuclear policy overhaul. But in an interview with The New York Times, Obama said he would make exceptions for "outliers like Iran and North Korea".
The emphasis of the new approach is on non-nuclear deterrence and eliminating Cold War ambiguities about when such weapons could be used.
Obama will unveil his strategy Tuesday, two days before signing a treaty with Russia to slash stockpiles of long-range nuclear warheads by a third, and less than a week before hosting world leaders at a nuclear summit in Washington.
In order to pursue a key foreign policy aim of halting nuclear proliferation, Obama has committed the US - the only country ever to unleash a wartime atomic bomb - to a series of nuclear arms cuts.
"The Nuclear Posture Review states very clearly: if you are a non-nuclear weapons state that is compliant with the NPT, you have a negative assurance we will not be using nuclear weapons against you," he told the Times.
"That doesn't mean that you might not engage in some actions that are profoundly detrimental to US national security, which require action on our part."
In a landmark speech in Prague in April 2009, Obama promised to work towards a world without nuclear weapons. But he has admitted he does not expect to see that goal reached during his lifetime.
From 12-13 April, world leaders will discuss in Washington the prevention of acts of nuclear terrorism and steps that can be taken to secure vulnerable nuclear materials.
Among those attending will be Chinese President Hu Jintao, under global pressure to swing behind imposing fresh sanctions on Iran for its continued refusal to rein in its suspect nuclear program.
French President Nicolas Sarkozy and German Chancellor Angela Merkel will also take part, along with high-level officials from nuclear-armed neighbours, India and Pakistan.


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The Family Fun Center Near 64120 You've Been Waiting For
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Party Time! We Make Birthday Parties Near 64120 Perfect
Your nearby Main Event is so much more than bowling lanes and arcade games. It's also one of the most affordable venues for birthday parties, group events, company holiday parties, and even team-building. Book your upcoming event online and experience the awesomeness for yourself. We take the stress out of party planning! Enjoy full-service catering with private party rooms, free Wi-Fi, big screen TVs, and the latest audiovisual technology. Need a kids birthday venue that doesn't disappoint? No problem. We handle everything, from the invitations to the clean up. Trying to plan an office party that even the accounting department will love? We can help there, too! Our party venues can make any occasion an amazing one. Book your next party or corporate meeting at Main Event to make it a memorable event!
Order Up! Visit The Best Family Restaurant Near 64120
Trying to have fun without food is like trying to bowl without a bowling ball. Work up an appetite and take a seat at our full-service restaurant and bar, featuring flavor-packed dishes and refreshing beverages. Pass around a shareable appetizer like crispy onion rings or coconut shrimp, then pick an entree that makes your tastebuds seriously happy. Choose from garden-fresh salads, signature pizzas, and chef-inspired cuisine like sirloin steak, perfectly grilled burgers, and even teriyaki salmon. For the kids, go with a quesadilla or crispy chicken fingers! End your meal with a scrumptious dessert that's as memorable as the time you spent with friends and family. Warm brownie sundae, anyone?
If you're hunting for the best sports bar, a family friendly pool hall, easy birthday party venue, or just a fun place to hang out with friends near 64120, you can find it all at Main Event. Come to the nearest location and unleash some epic fun today!

domain: entertainment


text:
Non-Western Epistemology and the Understanding of the Pachamama (Environment) Within the World(s) of the Aymara Identity
The purpose of this article is to understand, from the perspective of the Bolivian Aymara identity of Bolivia, the intrinsic relation these persons have with Nature. This task is developed through the study of what they call Pachamama (sacred Mother Earth), which is part of their identity as an ‘all interrelated whole, the Suma Qamaña or Good Living’, and which can be considered a non-Western epistemology. Their worldview breaks with the Western (anthropocentric) conception of environment that informs European and Anglo-Saxon continental law, and that is currently predominant in international standards of reference. Proponents of this perspective achieved a transformation in the international treatment of Nature, recognised by the United Nations (Resolution 63/278 of 2009, promoted by the Bolivian State), gaining inspiration from the inclusion by Ecuador of Pacha Mama (Nature) as a subject of rights in its constitution (2008).
Except where otherwise noted, content in this journal is licensed under a Creative Commons Attribution 4.0 International License.

domain: library


text:
|Agonia.Net | Policy | Mission||Contact | Participate|
|Article Communities Contest Essay Multimedia Personals Poetry Press Prose _QUOTE Screenplay Special|
￭ in return for your navy blue shirt
- - -
- - - - - - - - - - - - - - - - - - - - - -
2005-05-28 | | Submited by Edilberto Gonz├ílez Trejos
I walk on meadows run to weed,
on fields of burdock and mallow.
I know this rank and ancient ground -
this is the Magyar fallow.
I bow down to the sacred soil;
this virgin ground is gnawed I fear.
You skyward groping seedy weeds,
are there no flowers here?
While I look at the slumbering earth,
the twisting vines encircle me,
and scent of long dead flowers steep
my senses amorously.
Silence. I am dragged down and roofed
and lulled in burdock and in mallow.
A mocking wind goes whisking by
above the mighty fallow.
|Home of Literature, Poetry and Culture. Write and enjoy articles, essays, prose, classic poetry and contests.|


text:
The Tournament is open to teams composed of (18) or less players meeting the age limit of the listed divisions or (14) for U8, U9 & U10 players. Players must be born during or subsequent to the year indicated. Each team must be registered with a National Soccer Association and be registered in a league affiliated with the USSF or National equivalent. Teams from the United States must have a copy of a Permission to travel form. All games shall be played in accordance with the FIFA Laws except as specifically modified by the rules of the Tournament.
BRICKTOWN MEMORIAL DAY TOURNAMENT
May 24-25th, 2014
Format: Full sided Teams Gauranteed 3 games with a final. Trophies for 1st and 2nd place. Small Sided Teams will play 4 games with participation awards for all players. MVP Medals for small sided games will be awarded and will be chosen by the referees!
Brick is located at the Jersey Shore. We are close to beaches, boardwalk, and Great Adventure.
For more information and to register visit our website:
This tournament is fully integrated with the
GotSoccer Tournament Scheduler


text:
Hi hope you are all enjoying autumn!! I’m loving it this year and have really got into decorating for it. … More
Tag: autumn frame
Autumn frame diy!
Hi there! Hope you are having a lovely week! This week I wanted to make a Autumn frame for my … More

domain: design


text:
Rotator cuff tears are a common cause of shoulder pain in adults and often occurs without a traumatic injury, but are more of an overuse type injury. People have long since thought that following a rotator cuff tear all roads lead to surgery, however recent research is showing that physical therapy may be a better route, demonstrating similar outcomes and preventing an invasive surgery.
A study done in Finland found that physical therapy may be as effective as surgery for non-traumatic rotator cuff tears. The study looked at 167 patients over the age 55 (mean age of 65) who were diagnosed with a supraspinatus tear. The research was published in the January 2014 (Mossmayer et al, 2014) issue of Bone and Joint Journal and asserted that “conservative treatment should be considered as the primary treatment for non-traumatic rotator cuff tears”. In the study patients were assigned to 3 groups. One group received physical therapy only; another group received an acromioplasty and physical therapy; the third group received a rotator cuff repair, an acromioplasty, and physical therapy. Patients were assessed on the Constant Shoulder Score, which is a scale that is filled out by their clinician and rates pain, range of motion, strength, and activity level. The patients were assessed at 3, 6, and 12 month intervals and compared between groups and the study showed substantial similarities in the patients’ rate of improvement. The original hypothesis for the study was that the patients who underwent a supraspinatus repair would perform far superior to those who received an acromioplasty or conservative treatment alone. Likewise, the patients’ subjective satisfaction ratings were the same for all three groups.
A study done in 2017 (Royosa et al, 2017) demonstrated very similar results with no statistical significance noted in the conservative management group when compared with the surgical group. This study looked at 3 randomized control trials with a total of 252 participants (123 surgical cases and 129 conservative management cases). A 1 year follow-up was done with all participants to assess how their recovery was with their rotator cuff injury. There was a slightly lower report of pain and a slightly higher report of improved function in the surgical group, however the effect size was not statistically significant. Likewise, when compared to the risks and expenses that come with invasive procedures like surgical intervention, the non-surgical approach was found to be the best approach for initial treatment following a rotator cuff tear.
There was one final study that looked at 1, 5, and 10 year follow-ups of patients placed in either surgical treatment or conservative management (Mossmayer et al, 2019). This study looked at 103 patients divided 52 to 51 respectively (mean oage of 60) and followed them over the 10 year time frame. At the 1 and 5 year checks results slightly favored the surgical group, but both were found to be of no statistical significance, however at the 10 year follow-up the results showed that 10 of the 51 patients previously categorized into the conservative management category had undergone surgery, with seemingly good results. This study did demonstrate that conservative management of rotator cuff tears may only prolong the time before requiring surgical intervention, however in the 41 remaining conservative care group members positive results were still reported.
Overall, the general consensus seems to be that early conservative management is advised and if symptoms persist, surgical intervention may be required. This can be dependent on the patient and their specific needs, and also looks at how impaired their daily function is. If you are dealing with shoulder pain and would like to see if physical therapy can help or have a known rotator cuff tear and would like to try and avoid surgery, give us a call today and see if we can help.

domain: medical


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Conceptual sketches of the Islamic center planned two blocks from ground zero envision a futuristic-looking building wrapped in a honeycomb of abstract shapes, with a core containing far more space for secular pursuits than religious worship.
The renderings, some of which were posted on the project's website this week, are preliminary, but they project the development team's desire to build something cosmopolitan and fun on a site now known only for controversy.
"I don't think that once this thing gets built, anyone will be picketing," said Sharif El-Gamal, the project's developer.
Groundbreaking for construction is probably two to three years away, "or hopefully sooner," El-Gamal told The Associated Press.
The largest part of the building — four of 16 floors — would be taken up by a sports, fitness and swimming center. Another full floor would be occupied by a child care center and playground.
Much of the rest of the building would be occupied by a restaurant, culinary school, artist studios, exhibition space and an auditorium for cultural events.
El-Gamal said the idea was to build a facility that will attract neighborhood residents looking for a place to work out, as well as suburban Muslim couples spending "date night" in the city.
The building's prayer space for Muslims — the part of the center that has caused some critics to derisively brand the center the "ground zero mega mosque" — would be on two levels in the basement. The 12th floor would hold a 9/11 memorial and sanctuary open to people of all faiths.
As for the look of the place, it could fit in fine as an annex to Superman's Fortress of Solitude, with white walls and floors and a crystalline feel.
Renderings by Soma Architects, a design studio that shares office space with El-Gamal's real estate company, show a building exterior that takes a traditional element of Islamic architecture — an arabesque pattern — and weaves it into a geometric mash-up that extends into the interior.
"We want to have a marriage between Islamic architecture and New York City. We want to do something that is green and cool," El-Gamal said.
Actual working plans for the center are still some time away.
An architect has yet to be selected, El-Gamal said. Planning is just beginning to emerge from a brainstorming phase disrupted when criticism of the center exploded over the summer.
Fundraising will probably begin in earnest in about 30 days, once the work of establishing a nonprofit group to oversee the center is complete.
Like the project's co-leader, Imam Feisal Abdul Rauf, the Brooklyn-born El-Gamal said he was caught off-guard by criticism from people offended by the concept of building an Islamic institution so close to the World Trade Center site.
Some have called it an exercise in triumphalism, intended to plant Islam's flag at the scene of the attacks and deliberately provoke Americans. Others say they are against the center because they don't want to see any growth of Islam in the U.S.
"I would have done things a lot differently during this process if I understood what we were up against," El-Gamal said.
But he added that he remained convinced much of the criticism was sparked by "a campaign of deception and deceit."
"People have been calling this the ground zero mosque. It's not at ground zero and it's not a mosque," he said. "Our identity has been stolen from us. It has been stolen by extremists."
Opponents have sought to link people involved in the project to Islamic militancy, partly by looking for past public statements in which they were critical of the U.S. or Israel.
El-Gamal, who spent his early childhood in New York with his Polish, Catholic mother, then moved abroad with his Egyptian father, a Chemical Bank executive, after his mother died, says those efforts are ridiculous.
But he acknowledged that intense scrutiny of the project will make tasks like gathering donations and selecting board members more laborious.
"We're going to have to run this just like a political campaign," vetting every donated dollar to see where it comes from, he said.
The center has set a goal of raising $27 million through a nationwide appeal to Muslims, interfaith groups and other philanthropists, but most of the $120 million to $140 million needed for construction would be raised by issuing a type of bond common in Islamic banking.
The instrument provides some of the same borrowing benefits as a standard construction bond, but complies with a religious prohibition against charging interest on a loan. El-Gamal said he hoped the bonds could be issued by a public development authority, which would allow investors to get them tax-free, but said that is not essential to move the project forward.
Revenue for operations would come from membership dues. The goal is to have around 4,300 paying members, with about half paying $2,700 per year for a family plan that would include fitness center access.
Both the center's programming and business model were modeled largely after the Jewish Community Center in Manhattan, a popular facility on the Upper West Side where El-Gamal is a member.
El-Gamal said he hoped the prayer space would serve a congregation of around 2,000 people, most of whom would probably be Muslims who work downtown. Around 500 to 600 worshippers are already attending services at the site.
Big steps ahead for the project include resolving the relationship between the new nonprofit group that will operate the center, and the eight-person real estate investment partnership led by El-Gamal that controls the real estate on which it would be built.
Buying out the investment partnership is probably the first step, El-Gamal said, although the details of how that will happen are still not finalized.
One of his partners in the real estate deal, Hisham Elzanaty, has told The Associated Press that while he supports the idea of the center, he also needs his investment to turn a profit.
El-Gamal said Elzanaty was a partner, and that "his consent and approval" were necessary to the project, but he didn't foresee that as any obstacle.
A bigger challenge could be persuading enough New Yorkers that the project is just another community center. El-Gamal said he is optimistic his message will eventually break through.
He said the group is planning a series of town hall style meetings in which the relatives of 9/11 victims would be encouraged to voice their concerns.
At the very least, he said, the project is on the map.
"From a publicity standpoint, I think we've gotten $50 million worth of press," El-Gamal said. "It was good people that came together with good intentions, and when that happens, good things usually come out of it."


text:
Puerto Rico's population fell 11.8 percent to 3.3 million over the past decade, the U.S. Census Bureau announced Monday.
The population loss was part of the bureau's announcement of the latest data from the 2020 census on state and territory populations. The U.S. population overall grew 7.4 percent to 331.5 million over the previous decade, according to the census.
Puerto Rico has suffered a string of disasters and setbacks that have led to an exodus of island residents to the U.S. mainland.
Those include drought, near economic collapse because of crushing debt, earthquakes and thrashings from hurricanes, the worst of which was Hurricane Maria in September 2017.
Puerto Rico already was experiencing a population decline largely driven by migration and low birth rates before it was hit by Maria, according to a 2019 report by the Center for Puerto Rican Studies at Hunter College in New York City.
Maria thrust the island into darkness when it crushed its electrical grid, shut off water and food supply to residents, flooded and destroyed homes, forced school closings and shut down businesses. It resulted in the deaths of around 3,000 people.
With a slow response and recovery response from the U.S. government on top of the destruction, many Puerto Ricans from the island joined those who had already fled due to the economic crisis.
The island hit a peak of 3.8 million in 2004 but hasn't seen a population increase since then, according to the Pew Research Center. The current population is about what it was in the 1970s.


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Convert Your Garage into the Ideal DIY Workshop with a Place for Everything and Everything in Its Place
Build a Closet into the Space of an Existing Alcove by Adding Simple Framing and Doors
Design and Make a Custom Built-in Entertainment Center
by Ron Hazelton on November 23, 2015 in News
by Ron Hazelton on November 17, 2015 in News
by Ron Hazelton on September 29, 2015 in News
Viewing Project in Storage & Cabinets > Cabinets > Shelving
I've built a number of these for all of my hand tools. Now everything is organized and I can actually find the tool I need!
This is just what we were looking to do in our shop. Perfect Idea
Great idea! I built mine with five levels and enclosed the whole section with doors and now can keep up with over a hundred tools and it is neatly stored.
yes how far apart should you put the panels
I love watching your videos, I am a women that has some experience helping my dad when I was a kid …. the help my dad needed was mostly handing them tool, bring him stuff put it was a great time I was the youngest and the only girl. I love the way you explain on each video thanks for making things much easier.
Thanks Ron, This is just what I need for my shop.
How did it turn out?
I agree with the framed peg board as you can easily change the configurations for various tools.
Good idea but it seems like framed pegboard would be more functional since you would have multiple options to hang tools and it would also be lighter and less costly than 3/4" ply.
I follow Ron's Site weekly and this is one of the most useful ideas I have seen. I have limited space and a lot of tools and always looking for another way to store them, this will work just fine.
My question is how far apart do you have or need to put the "pages" of your book? I saw every measurement but that.
look again but on the top of the stud finder it marks like a laser to indicate the edge of the stud
WOW...Ron, you always show us how, to construct, build, repair, Everything...and always in a definite & positive, ways & means.. This is fantastic , to build this Foldable storage system, for much needed hand tools...Tremendous for all this extra space, this provides us..Many Thanks
Fantastic. I thought about the hinge mounting solution and you confirmed it. Something to look forward to in my new home.
The concept is great.In your video, the red-light, you referred to,on the stud finder appeared green on-camera.
I like this one for sure!! Thanks Ron
I love this with all the tools I have it will save me lots of room for other items.
A great tip as alway. Thanks Ron...
Ingenious! My husband can now be more organized very easily.
Wow, this could be used in a tiny home for kitchen tool storage as well as in the basement for tool storage. Really great for anywhere space is at a premium. Love this idea.
A GREAT PROJECT, EASY TO BUILD , LOW COSTSPACE SAVERKENNETH
a great project
Didn't see it closed Ron ... why?


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Find a great deal and save up to 172% by booking at least 49 days prior to your desired departure date, rather than waiting until the week of travel. According to our data, there are a number of flights available from Cambridge to Gdansk within the next two weeks, with the cheapest ticket starting at £79.
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domain: travel


text:
Janet Tiffin has died. He was reported dead March 16, 2020 on the Barrie Sharks Twitter page. The cause of death is unknown yet.
Janet Tiffin passed away recently. The news of his passing has brought condolences and tributes on social media.
DeadDeath is yet to learn of the obituary publication / funeral arrangement. We will make updates available on this post.
Janet Tiffin Death | Janet Tiffin Obituary – Cause Of Death
More on DeadDeath: Jerry D. Baker Death | Killed On US 278 Accident


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The Colorado Times Recorder reports:
“CALL TO ACTION” blared the headline of the Colorado Republican Party’s email last week. What was so important that state GOP blasted an all caps request to its entire list?
“Your support is needed for the January 6 prisoners. Please see the letter below and if you want to be included, please respond to this email and we will add your name to the list. Also, please distribute this to your county and/or constituents for them to give us their permission to include their names as well.”
State GOP Secretary Anna Ferguson, who has publicly stated her belief in the QAnon conspiracy, signed the email. El Paso County Vice Chair Todd Watkins [photo], himself an unapologetic election denier, wrote the letter itself.
Read the full article. Watkins ran for county sheriff last year and lost the GOP primary by 23 points. The Colorado GOP’s newly appointed treasurer took part in the Capitol riot, which he now blames on antifa.
— Colorado Times Recorder (@COTimesRecorder) August 30, 2023
Democrats love to let criminals loose on the streets.
This is what happens when you elect woke crime-huggers to power.
— Colorado Republican Party (@cologop) May 13, 2023
The true face of the Colorado Democrats.
They are racist and communist, and want to teach your kids to be the same.
— Colorado Republican Party (@cologop) August 28, 2023


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Kolar: Former Chief Minister Siddaramaiah’s defeat in Kolar is certain, said MP S. Muniswamy.
Addressing a press conference, he said that Siddaramaiah will contest from Kolar. However, in the last elections, there was a difference of 40,000 votes between the Congress candidate and the sitting MLAs. There are 4 to 5 groups in the Congress like Ramesh Kumar, K. H. Muniyappa, Byalahalli Govinda Gowda, Siddaramaiah, and a team from the State. And we will defeat all of them this time and send them away,” he said.
“The Congress, which had divided India for the last 70 years, is now deceiving the people by saying Bharat Jodo. He lied to MLA K. Srinivasa Gowda that he would become an MLC-Minister. We are yet to announce the candidates, there are two aspirants in Kolar and whoever gets the ticket, we will work sincerely,” he said.


Understanding the geographic occurrence of mosquito species is an important element to addressing public health and nuisance mosquito-related issues, particularly as changing climates and increased global connectivity is likely to facilitate changes in the distribution of mosquitoes and other species. In Charlotte County, FL, routine surveillance of mosquito species for public health in 2019–21 identified 4 mosquito species not previously documented in the county. Aedes pertinax, Anopheles perplexens, Culex declarator, and Cx. interrogator adults were collected and verified to species level. Aedes pertinax and Cx. declarator and were collected in 2019, whereas An. perplexens and Cx. interrogator were documented from collections in 2021. All 4 species were initially visually identified by external morphology and confirmed by sequencing the DNA barcoding region of the cytochrome c oxidase subunit I gene. Apart from native An. perplexens, in which only 1 specimen has been confirmed to date, the 3 newly documented nonnative species are now recognized throughout the county.
Nonnative mosquito species have been detected within the state of Florida over the last 20 years, with 5 species being detected within Florida's boundaries in just the past 7 years. These introductions may be attributed to a changing climate where increasing temperatures encourage mosquito migration from the South in addition to global connectivity in which mosquitoes can be inadvertently introduced through transports (Lounibos 2002, Franklinos et al. 2019). Recent ecological models have resulted in a heightened awareness across the state for nonnative detections as they are often invasive vector species (Campbell et al. 2021, Sloyer et al. 2022). During 2019–21, Charlotte County has documented 4 new species of adult mosquitoes, including Aedes pertinax (Grabham), Anopheles perplexens (Ludlow), Culex declarator (Dyar and Knab), and Cx. interrogator (Dyar and Knab). While public health implications of Ae. pertinax and An. perplexens are currently unknown in the USA, Cx. declarator has been implicated as a vector of the dog heartworm, Dirofilaria immitis (Leidy) (Labarthe et al. 1998, Darsie and Shroyer 2004), and Cx. interrogator is a known carrier of Culex flavivirus (Saiyasombat et al. 2010). Mosquito control public health agencies have indicated the need for implementing protocols to deal with detections of nonnative species, especially introduced invasives that are known to transmit pathogens of public health importance (Kondapaneni et al. 2021, Dye-Braumuller et al. 2022, Wilke et al. 2022). County-level species voucher records are a crucial stage of the process and should be taken with forethought to assist in the baseline collection of data for improving the detection of nonnative and invasive mosquito populations in any region surveyed by public health agencies (Darsie and Morris 2003, Riles and Connelly 2020).
Aside from An. perplexens, a native species in Florida, the other three hold nonnative status where their respective first detections in the state occurred from 2004 through 2016 (Darsie and Shroyer 2004, Shroyer et al. 2015, Shin et al. 2016). Anopheles perplexens is typically found in localized areas of the eastern USA, including northern and central Florida (Darsie and Ward 2005, Burkett-Cadena 2013). Aedes pertinax was originally limited to the Caribbean Islands (Darsie et al. 2010), and both Cx. declarator and Cx. interrogator are found in portions of southern Texas with ranges extending south through Mexico and Central America (Bram 1967, Darsie and Ward 2005). The possible range expansion demonstrates the need for heightened awareness across the state concerning identification of unknown mosquito species and their migration (Boehmler 2022, Short et al. 2022, Tyler-Julian et al. 2022). Standard microscopy methods using dichotomous identification keys is the forefront of determining species diversity locally and regionally; however, it does not always ensure accuracy due to reliance on specimen quality, similar characteristics among species within the same genus, and/or total absence of species in regional identification keys (Darsie and Morris 2003, Darsie and Ward 2005, Reeves et al. 2021, Riles 2021). For these reasons, the procedure of cytochrome c oxidase subunit I (COI) sequencing should be implemented in addition to visual identification methods to ensure accuracy when reporting the occurrence of unknown species introduced into any area that is being surveyed for public health, although it is important to have an accurate molecular reference collection available in addition to Barcode of Life Datasystems (BOLD) Identification Tool reference sequences. Here we report on the introduction of the aforementioned 4 species in Charlotte County, FL.
MATERIALS AND METHODS
Surveillance and visual identification
Charlotte County Division of Mosquito and Aquatic Weed Control (FL) performs county-wide surveillance at 17 routine static locations using the Centers for Disease Control and Prevention (CDC) miniature light traps (Model 512; John W. Hock Company, Gainesville, FL; hereafter referred to as CDC light traps). The CDC light traps were set with only incandescent light (Model No. CM-47, 6.3 V; John W. Hock Company) as an attractant, no other lures or attractants were used. Traps were set biweekly and operated for 24 h per collection period. Mosquitoes collected were brought to the laboratory and stored at −18°C for 1 h to ensure mortality. Mosquitoes were then sorted out from other insects and morphologically identified under a dissecting microscope (National Trinocular, 10–40× Stereo Zoom [420 series], Schertz, TX), using dichotomous identification keys (Darsie and Morris 2003, Darsie and Ward 2005), and recorded into the VectoStar (Skysoft Inc., Orlando, FL) database management system. Observed unknown or morphologically questionable species were placed into vials labeled with collection date, location, tentative species determination, and stored at −18°C for later visualization and/or DNA analysis. For DNA preparation, each specimen was placed in 95% ethanol for the DNA barcoding analysis comparing known COI gene sequences (Hebert et al. 2003).
Collections and habitats
Culex declarator was first collected and identified in Charlotte County on June 20, 2019, in a wooded residential lot in the western portion of the county (26°56′13.7328″N, 82°15′52.0272″W). In August 2019, 3 females were collected in the central portion of the county over 3 trap locations within semirural and suburban habitat designations (27°0′30.604″N, 82°5′16.288″W; 26°57′18.264″N, 81°59′16.748″W; 27°0′53.733″N, 82°3′38.044″W). The following year, 86 females were trapped at an additional 8 sites across the county.
Aedes pertinax was first recognized in Charlotte County on July 12, 2019, from a semirural trap site (26°55′14.9772″N, 82°0′53.2512″W) located in a patch of woods near an open grassy area. Thereafter, during the months of July and August, the species was documented at 15 out of all 17 trap sites with a mix of habitats ranging from rural to residential. The species often co-occurs with Ae. atlanticus Dyar and Knab and Ae. infirmatus (Dyar and Knab), all of which share similar morphologic characteristics.
In October 2021, specimens suspected to be Cx. interrogator (n = 10, F) were collected in Charlotte County from a rural oak hammock habitat in the eastern part of the county (26°59′7.278″N, 81°52′14.4876″W) and kept frozen according to analysis protocols until confirmation could be made. Subsequent collections (n = 5, F) were made in October through December at a semirural wooded site (26°57′18.264″N, 81°59′16.748″W) located just 7.5 mi southwest of the initial detection and a collection of 2 females was obtained from a 3rd site (26°56′15.015″N, 82°1′50.499″W) in November. All sites with these initial collections are located east of the Peace River.
A female mosquito tentatively identified as An. perplexens was collected on November 2021 at a wooded semirural site (26°57′18.2628″N, 81°59′16.7496″W). As of yet, no An. perplexens have been detected in neighboring Lee and Sarasota counties to the south and north, respectively. Initial collections are depicted in Table 1 and Fig. 1.
One representative adult specimen of each tentatively identified species was sent to the Florida Medical Entomology Laboratory (FMEL) Reeves Lab in Vero Beach, FL, for molecular analysis. From each of these specimens, one midleg was removed with flame-sterilized forceps and transferred to a 1.5-ml microcentrifuge tube. The remainder of each mosquito specimen was mounted on an insect pin and preserved as a voucher in the Reeves Lab reference collection. DNA was extracted from the detached mosquito legs using the Zymo Quick-DNA Miniprep Plus Kit (Genesee Scientific Corp., El Cajon, CA). After the 1st extraction buffer was added to the tube, the leg was macerated for approximately 3 min with a sterile plastic pestle. All subsequent steps followed the manufacturer's protocol. The barcoding region of the COI gene was amplified for each mosquito specimen by polymerase chain reaction (PCR) using either the LepF1 and LepR1 primers (Hebert et al. 2004) or the LCO1498 and HCO2198 primers (Folmer et al. 1994). Regardless of the primer pair used, each PCR was performed in a final volume of 25 μl that consisted of 10 μl 2× Apex Taq RED Master Mix (Genesee Scientific Corp., San Diego, CA), 2 μl of 10 μM forward primer, 2 μl of 10 μM reverse primer, 1 μl of extracted DNA, and 5 μl of sterile water. Thermal cycling conditions for each PCR were 94°C for 1 min, 5 cycles of 94°C for 30 sec, 45°C for 40 sec, and 72°C for 1 min, 35 cycles of 94°C for 30 sec, 51°C for 40 sec, and 72°C for 1 min, followed by a final extension step of 72°C for 10 min. Seven microliters of each PCR product was electrophoresed on a 1.5% agarose gel for 45 min and visualized under a transilluminator to ensure amplification of a PCR product of the expected size. Amplicons were sent to Eurofins Genomics (Louisville, KY), where they were cleaned and sequenced using chain-termination sequencing (Sanger et al. 1977). The resulting DNA sequence chromatogram files were visualized in the bioinformatic software Geneious Prime 2020.1.2 Version 11.0.6 (Biomatters, Inc., San Diego, CA), and each sequence was examined and edited for quality.
Edited COI sequences were queried on the BOLD v. 4 Identification Engine for species-level identification by alignment to reference COI sequences (Ratsnasingham and Hebert 2007). Limitations to identifying mosquitoes through DNA barcoding include incomplete taxonomic coverage of reference sequences in publicly accessible databases and the existence of misidentified reference sequences and reference sequences that are not identified to species level (Beebe 2018). These issues are particularly relevant to An. perplexens (reference sequences absent from BOLD), and Cx. declarator and Cx. interrogator (misidentified reference sequences). To circumvent these limitations, COI sequences from the Charlotte County mosquito specimens were aligned to reference sequences curated by the Reeves Laboratory and derived from reliably identified specimens. Sequences from Charlotte County Ae. pertinax, An. perplexens, Cx. declarator, and Cx. interrogator were aligned to other Florida species from the Aedes subgenus Ochlerotatus, Anopheles subgenus Anopheles, and Culex subgenus Culex, respectively. From these alignments, neighbor-joining trees were constructed using the Geneious Tree Builder tool (Geneious Prime Version 11.0.6), with the Jukes–Cantor genetic distance model.
Based on the results of BOLD Identification Tool queries and neighbor-joining trees, DNA barcoding sequences confirmed the morphological identification of Ae. pertinax, An. perplexens, Cx. declarator, and Cx. interrogator in Charlotte County. The COI sequence from the specimen morphologically identified as Ae. pertinax was highly similar (>99%) to BOLD reference sequences labeled as Ae. pertinax and Ae. serratus (Theobald) collected on the Yucatan Peninsula. The latter species is morphologically similar to Ae. pertinax. In the neighbor-joining tree (Fig. 2), the Charlotte County Ae. pertinax sequences grouped together in a clade with sequences derived from other Florida Ae. pertinax specimens collected in Indian River, Miami-Dade, and Lee counties. This clade was distinct from those of all the other Aedes Protoculex Group species (Ae. atlanticus, Ae. dupreei Coquillett, Ae. tormentor Dyar and Knab) that occur in Florida, and similarity among sequences in this clade range from 98.7% to 100%. The COI sequence for the An. perplexens specimen did not match any BOLD reference sequences. Reference sequences labeled as An. perplexens have been uploaded to BOLD, but all are essentially identical to reference An. punctipennis Say sequences. Anopheles punctipennis is morphologically similar to An. perplexens. In the neighbor-joining tree (Fig. 3), the Charlotte County An. perplexens sequence formed a clade with other Florida specimens identified as An. perplexens from Brevard, Hillsborough, and Osceola counties. This sequence was 99.49–100% similar to other sequences in this clade. For Cx. declarator and Cx. interrogator, BOLD Identification Engine results were ambiguous, with Charlotte County COI sequences highly similar to reference sequences labeled as multiple Culex species. These results likely reflect the challenges with distinguishing several of the species of the subgenus Culex. In the Culex neighbor-joining tree (Fig. 4), sequences from the Charlotte County specimens of both species each formed respective clades with sequences from Florida Cx. declarator specimens from Indian River and Collier counties and Florida Cx. interrogator specimens from Osceola and Palm Beach counties, with each clade distinct from those of all other included Culex species.
Culex declarator, since the initial 2019 collections, has been observed in low numbers (n = 103) across multiple collection sites, possibly indicating establishment with a relatively even distribution. Currently no larvae have been collected for this species. The potential public health implications of Cx. declarator are unclear in Florida, although the species has been implicated as a vector for D. immitis due to their host preference of canine-baited traps (Labarthe et al. 1998, Darsie and Shroyer 2004). In 1998, Cx. declarator was first reported in Florida in Indian River County and did not become abundant until September 2003 (Darsie and Shroyer 2004). Prior to this, Cx. declarator was present in the USA only in portions of southern Texas (Breland 1954, Darsie and Ward 2005), though from there its geographic distribution extends south through Central America, the northern half of South America, and the Lesser Antilles (Bram 1967).
Aedes pertinax, since the initial detection in Charlotte County, FL, has been documented at nearly all surveillance sites (n = 703); currently no larvae have been collected for this species. The species had likely been collected prior to its detection but incorrectly identified as Ae. atlanticus due to similar morphologic characteristics at gross level as described by Shroyer et al. (2015). Shroyer et al. (2015) reported the first detections of Ae. pertinax in the USA through collections in Indian River County, FL, in 2011 and verified its presence through performing a morphometric genetic analysis. Prior to this, Ae. pertinax was known only from the Caribbean Islands (Darsie et al. 2010), which may serve as a corridor for mosquito introductions into the Florida Peninsula (Darsie and Shroyer 2004, Blosser and Burkett-Cadena 2017, Burkett-Cadena and Blosser 2017, Campbell et al. 2021). Voucher specimens were obtained from Sarasota County Mosquito Management Services to perform the initial verification of Ae. pertinax, which was further confirmed by DNA barcoding. Trained individuals need to have heightened awareness in Florida concerning the separation of morphologically similar mosquito species such as Ae. atlanticus, Ae. tormentor, and Ae. pertinax (Sither et al. 2013, Shroyer et al. 2015, Harrison et al. 2016). Refer to Shroyer et al. (2015) for morphological characters relevant to separating Ae. pertinax from other Florida Protoculex Group Aedes.
In 2013, Cx. interrogator larvae were collected in Broward County, FL (Shin et al. 2016). Prior to this detection, the US distribution of Cx. interrogator was limited to a few counties in Texas (Carpenter and LaCasse 1955, Darsie and Ward 2005) where the species reaches the northern limit of its distribution, occurring south through Mexico and Central America. Culex interrogator was previously understood to be absent from the Caribbean (Bram 1967) but has recently been reported for the first time from Cuba (Menzies et al. 2018) and Hispaniola (Sosa et al. 2020). Since its introduction into Florida, Cx. interrogator has migrated to multiple counties throughout the state (Riles and Connelly 2020). Collaboration with Lee County Mosquito Control District, a neighboring county to the south, helped to determine this was most likely Cx. interrogator via characteristic descriptions and photography of Lee County, FL, reference specimens. Once Cx. interrogator was determined, a specimen was sent to FMEL for COI sequencing verification where it was confirmed. Culex interrogator has been collected across 5 different sites (n = 20, F) in Charlotte County through the end of 2021; however, larvae of this species have not been collected in Charlotte County to date. Catch locations range from central to eastern portions of the county, with 4 sites designated as rural habitat and one a residential locality. The public health significance of Cx. interrogator in Florida is currently unknown, although pools in the Yucatan Peninsula of Mexico have been found infected with Culex flavivirus (Saiyasombat et al. 2010).
Anopheles perplexens is an uncommon mosquito that occurs in localized and disjunct areas of the eastern USA, including northern and central Florida (Darsie and Ward 2005, Burkett-Cadena 2013). Little is known concerning the medical importance of this particular species. To date, this has been the only confirmed An. perplexens collected in Charlotte County and the most recently discovered species in the county. This mosquito is morphologically similar to An. punctipennis and older, worn specimens may be confused for An. crucians Weidemann complex species.
Historically, routine trapping methodologies have remained unchanged in Charlotte County since CDC light traps were implemented several decades ago. Whereas many districts use lures and attractants such as CO2 in addition to a light source, Charlotte County has only used the incandescent bulb that comes standard on a John W. Hock Company model 512 CDC light trap for routine 24-h site surveillance. That is not to say other trap types and attractants aren't currently being used for auxiliary collections, but to maintain baseline accuracy, all 17 routine static trap locations are still monitored in the original manner. Perhaps the biggest advantage of this method is a more manageably sized mosquito catch in which every single species is identified as opposed to aliquots where a new or rare species might be missed. Usual summertime trap catches using this method range from dozens up to over 2,000 mosquitoes in a single trapping period, with overall annual catches averaging 78 mosquitoes per catch period. In addition to manageable catch sizes, since the traps are run for 24 h, catches are not limited to mosquito species that are only active during crepuscular periods.
Due to operational constraints, localized collections of larvae for the purpose of identification are not often feasible and therefore have not been implemented as a standard form of species surveillance. While the nonnative species of Ae. pertinax, Cx. declarator, and Cx. interrogator have become commonplace in Charlotte County CDC light trap collections since initial detections, determination of establishment cannot be confirmed until respective larval collections are made. Because of this, current and future focus will be centered on obtaining an increased number of larval collections in an attempt to verify where the species are originating from.
The addition of 4 previously undetected species (Fig. 5) within the span of 3 years is quite significant. Documented species in Charlotte County have increased over this period by 10.5%, from 34 to 38 mosquito species. Culex declarator and Cx. interrogator occur in portions of southern Texas that share the same latitude as Charlotte County within the 26° parallel, so it is not surprising the county would be ecologically suitable for these species once they were introduced into Florida. Aedes pertinax was most likely established in the county prior to 2019, but because this species was not included in the Darsie and Morris (2003) or Darsie and Ward (2005), the primary resources used for morphological mosquito identification in Florida, specimens were considered anomalous to Ae. atlanticus at gross levels and perhaps misidentified. Anopheles perplexens is known to have sporadic distributions and is known to exist in the northern and central regions of Florida based on information from distribution maps of regional and national identification keys (Darsie and Ward 2005, Burkett-Cadena 2013) where peer-reviewed checklists of mosquito species suggest migration within northern Florida counties (Smith et al. 2020). For these reasons, along with changing weather patterns, it is important to remain vigilant when identifying mosquito species. Using references such as identification keys from multiple regions and recent peer-reviewed taxonomic literature along with communication with neighboring mosquito programs and molecular confirmation of morphological species identification can assist in recognizing when unknown or previously undetected species are first discovered.
Special thanks to Wade Brennan, Sarasota County Mosquito Management Services, and Kara Tyler-Julian, Lee County Mosquito Control District, for their help and communications with regards to newly encountered species. The authors would also like to show their gratitude to Roxanne Connelly for reviewing a previous draft of this manuscript.
Charlotte County Mosquito & Aquatic Weed Control, 25550 Harbor View Road Suite 2, Port Charlotte, FL 33980.
University of Florida, Florida Medical Entomology Laboratory, 200 9th Street SE, Vero Beach, FL 32962.
Beach Mosquito Control District, 509 Griffin Boulevard, Panama City Beach, FL 32413.


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By Uday Sampath Kumar
(Reuters) – U.S. stock index futures rose on Monday as the top U.S. trade negotiator said a deal would nearly double exports to Beijing over the next two years, but Boeing was set to cap gains for the S&P 500 and on production concerns about its grounded jet.
Boeing Co (N:), which normally benefits from trade talk progress, fell 3.2% premarket. The planemaker is considering whether to cut or halt production of its grounded 737 MAX airliner, Reuters reported.
All three major stock indexes hit record highs on Friday after the world’s top two economies announced a much-awaited “phase one” agreement, but ended largely flat as investors looked for clarity on the actual text of the pact.
On Sunday, U.S. Trade Representative Robert Lighthizer said there would be some routine “scrubs” to the text, but that it was “totally done”, adding that the date to formally sign the agreement was being determined.
The preliminary deal suspended U.S. tariffs on $160 billion worth of Chinese imports scheduled to take effect on Dec. 15, and reduced some duties in exchange for increased purchases of U.S. agricultural, manufactured and energy products by Beijing.
Nasdaq futures hit an all-time high earlier on Monday, while S&P 500 futures hovered near record levels. The benchmark index is on track for its best annual performance since 2013, boosted in part by three interest rate cuts by the Federal Reserve and encouraging economic data.
At 7:15 a.m. ET, were up 44 points, or 0.16%. S&P 500 e-minis were up 12.25 points, or 0.39% and were up 36.75 points, or 0.43%.
Shares of International Flavors & Fragrances Inc (N:) fell 6.1% after it said it would merge with DuPont Inc’s (N:) $26.2 billion nutrition & biosciences unit. DuPont’s shares rose 4.5%.
Micron Technology Inc (O:) rose 2.8% and was the biggest gainer among chipmakers after Susquehanna raised its rating on the stock.
Investor attention now turns to Markit PMI surveys for the manufacturing and services sectors for December, due at 9:45 a.m. ET.
Fusion Media or anyone involved with Fusion Media will not accept any liability for loss or damage as a result of reliance on the information including data, quotes, charts and buy/sell signals contained within this website. Please be fully informed regarding the risks and costs associated with trading the financial markets, it is one of the riskiest investment forms possible.


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In your Kashmir tour, one of the most serene and idyllic experience is staying in a houseboat. Often found in Srinagar, a houseboat stay is magical and will make you fall in love with Kashmir all over again. It is also an extremely popular activity and Kashmir generates a lot of revenue for these houseboat stays.
Most of the houseboats are stationed at either the iconic Dal Lake or the Nagin Lake. While the latter is less popular, it is as stunning and enchanting as the Dal Lake. It is also less crowded, make your experience even more surreal.
To reach the houseboats, you have to sail on a Shikaras, which are similar to the Gondolas in Venice. These Shikaras have been famously used in Hindi films as icons of romance. Shikaras are also mesmerising and are a world of their own.
To reach the beautiful houseboat floating in the middle of the serene lake, you need to first board a vibrant Shikara on your Srinagar Tour. The Shikara ride itself is quite scenic and you will find yourself traversing through the idyllic lake and the peaceful life of Srinagar.
Your luggage will also ride with you on the Shikara to the landing of the houseboat. Usually, the moment you enter, you are served a warm Kashmiri tea that will transport you to the fragrant orchids of Kashmir. You might also find vendors selling mache papers, hand-painted boxes, tinkering bells, fluorescent bangles, floral trays and other such items. There will be other vendors as well, you might be selling ethnic Kashmiri Jewellery. Try and bargain as much as you can and make your Shikara ride a little more eventful. It almost feels like you are riding with a market on board.
One of the best times to ride a Shikara is as the sun begins to set. Watch as lake turns into a golden hue and the entire valley assumes a beautiful kind of silence. It is so regal to gently sail away into the lake, as the winds hit your face and the sky Strats painting Srinagar.
Gradually you will start to see many houseboats lined up in the middle of the lake. There are many well-known hotel chains also those own houseboats and offer them to tourists. This site is worth watching, with dozens of palatial houseboats lined up, all covered in wooded panels and lovely verandah emerging from all of the boats.
The houseboats are connected to the land, however, the locals will always use Shikaras to bring tourists to give an illusion, that the houseboats are situated right in the middle of the lake.
While Shikaras are known for their vendors and pop shops, you will also find many photographers right as you deboard the shikhara to go on your houseboat tour. These photographers have a whole bunch of Kashmiri clothes which you can don right there in that shikhara, as it precariously sways from one side to the other. Then, pose away on your Srinagar tour, and be the Kashmiri Ki Kali on your Instagram photos. If you do not wish to pay a good amount of money for the printed photographs, then just give them your camera. They will click some photos on your camera for a small fee.
While on your Shikara journey, your guide will also point you towards a unique floating vegetable garden. It is quite a delightful sight. A plethora of vegetable vendors ride on their boats brimming with vegetables. It is perhaps one of the most photogenic and quirky sights in Srinagar. The other floating market in Asia is located in Thailand.
When you finally reach your destination on your Srinagar tour, you will find all the houseboats lined up waiting to be explored. In Srinagar, these houseboats look as if an entire village is surrounded by the lake. These houseboats in Srinagar are found in the Dal Lake and the Nagin Lake.
The houseboats in Srinagar are well suited for tourists with different preferences. There are a few rooms, a dining room, a common room and private bathrooms. The interiors are extremely cosy and will make you feel at ease.
There is also a little balcony that overlooks the chilled waters of the lake and gives you a view of the entire horizon. Watching the sunrise and the sunset from this balcony is surreal. Just wake up early in the morning, make your self a kawah, and watch as the sun starts to wake up from its slumber and enlightens the place. The misty fog covers the valley in a haze, and just as the sun begins to rise the haze starts to make for the rays of the sun. As the light touches Srinagar, the flowers sellers on their shikhara start wandering about and sail past the large houseboat.
Next morning on your houseboat tour, take around on a luxury boat that is located right around your houseboat. These luxury boats have intricate and pristine wood carvings. They also have little bathrooms with all kinds of facilities and every single piece of furniture is made by the fine local artisans of Kashmir. The work is so precise and beautiful that you will get lost in the cervices of the work. The carvings depict the flora and fauna of Kashmir and some of them show the culture of the valley.

domain: geography


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Construction on River Watch Parkway is heading into its final stages as we approach Masters Week.
The project, stretching from 15th street to River Shoals Parkway, has been on-going since October.
Kyle Collins with the Georgia Department of Transportation said a new drainage system's been put in. Crews are now finishing replacing guardrails with concrete barriers, last step is lighting.
"There's a ton of light poles going up. It's going to light up the entire corridor coming into downtown. Actually 200 light poles are going in as part of this project as well,” Collins said.
Workers are laying the foundation for the light poles right now, but they won't go in until after the Master's. GDOT said with the amount of traffic they are expecting to see come through River Watch Parkway the week of the tournament, they are taking all safety precautions. There will be no crew workers out there working and all lanes will be back open.
The project's completion date is not until July but GDOT said its months ahead of schedule. As long as weather permits, the $9 million project will stay ahead of the game.
"It's important to highlight these improvements are thanks to TSPLOST, the Transportation Investment Act, TIA dollars that the folks in the CSRA voted on. That's really their tax dollars going to work on that project,” Collins said.
Resurfacing of the 4 mile stretch will also happen. That's expected to start between May and June.


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California Gov. Gavin Newsom and the state Legislature are working on a coronavirus aid plan for the state’s illegal immigrants and others not covered by the federal government’s $2.2 trillion relief package.
Newsom, a Democrat, disclosed the plans Tuesday, according to The Associated Press.
“Californians care deeply about undocumented residents in this state,” the governor, a former mayor of San Francisco, said.
“Californians care deeply about undocumented residents in this state.”
But some California Republicans have spoken out against the plan.
“I see the state of California and its budget as a house of cards and with this coronavirus-induced recession, I’m just trying to figure out where the money would come from,” state Sen. John Moorlach, a Republican from Costa Mesa, told the AP. “I would say helping undocumented would be a luxury item.”
“I would say helping undocumented would be a luxury item.”
About 2 million people are believed to be living in California illegally, according to the California Latino Legislative Caucus. The group requested that Newsom create a “disaster relief fund” to provide financial assistance to those immigrants who haven’t been able to work during the state’s stay-at-home order because of the virus.
Under the federal relief plan that President Trump signed into law last month, American adults making less than $75,000 annually will receive checks for $1,200 and couples making less than $150,000 will receive $2,400 – provided they use a Social Security number when filing their tax forms.
But illegal immigrants are not eligible for the federal plan, regardless of whether they pay taxes from their paychecks.
Newsom said a plan he intends to unveil in May will offer some relief for illegal immigrants, adding California is “not just waiting for the federal government to do that for us.”
The Associated Press contributed to this story.


Union Home and Cooperation Minister Shri Amit Shah inaugurated Mega Dairy at Mandya in Karnataka today. Several dignitaries including Nirmalanandanatha Mahaswamiji, the 72nd Pontiff of Sri Adichunchanagiri Mahasamsthana Math, Mandya, Chief Minister of Karnataka, Shri Basavaraj Bommai, former Prime Minister Shri HD Deve Gowda and Union Minister of Parliamentary Affairs and Coal and Mines Shri Pralhad Joshi were present on the occasion.
Condoling the demise of Prime Minister Narendra Modi’s mother, Shri Amit Shah paid tributes to her and said that the whole country is standing with the Prime Minister in this hour of grief. The Union Home and Cooperation Minister said that since independence, the farmers of the country had demanded a Ministry of Cooperation separate from the Ministry of Agriculture. He said that he would like to thank Prime Minister Narendra Modi for paving the way for the development of farmers by forming a separate Ministry of Cooperation. Shri Shah said that from the inaugural platform of Mandya Mega Dairy, he wants to tell the cooperative workers across the country that it is the decision of the Government of India that there will be no injustice to the cooperatives.
The Union Cooperation Minister said that the mega dairy inaugurated today at a cost of Rs 260 crore would process 10 lakh liters of milk per day and the will have the capacity to increase it upto 14 lakh liters per day. He said that when 10 lakh liters of milk is processed, prosperity reaches the homes of lakhs of farmers. Shri Shah said that in Karnataka, the cooperative dairy is working very well. Today, there are 15,210 village level cooperative dairies in Karnataka, in which about 26.22 lakh farmers deliver their milk daily and through 16 district level dairies, Rs 28 crore is deposited into the accounts of 26 lakh farmers every day.
Shri Amit Shah said that around 66,000 kg milk used to be processed daily in Karnataka in 1975 while today over 82 lakh kg milk is processed daily and 80% of the total turnover goes to the farmer. The Union Cooperation Minister said that the White Revolution in Gujarat has changed the fortunes of the farmers and through Amul, 60,000 crore rupees is deposited into the bank accounts of about 36 lakh women annually. He said that he would like to assure all the farmer brothers and sisters of Karnataka that Amul and Nandini will work together towards establishing primary dairies in every village of Karnataka and in next three years there will not be a single village in Karnataka where primary dairy has not been established. Shri Amit Shah said that the government has decided that the National Dairy Development Board (NDDB) and the Ministry of Cooperation will establish a primary dairy in every panchayat of the country in the next three years and a complete action plan has been prepared in this regard. He said that with this, two lakh primary dairies will be established at the village level across the country in three years, through which India will emerge as a big exporter in the milk sector by connecting the farmers of the country with the White Revolution.
The Union Home and Cooperation Minister said that Karnataka Milk Federation will be provided with technical support, cooperative sector support and overall functioning support from Amul and all its requirements will be addressed by the Ministry of Cooperation. He said that Gujarat and Karnataka together can work for the welfare of the milk producing farmers of the whole country. Union Cooperation Minister appreciated the Government of Karnataka under the leadership of Chief Minister Basavaraj Bommai for ensuring depositing Rs 1,250 crore directly to bank accounts of milk producing farmers through DBT at the rate of Rs 5 per liter during the year. Shri Amit Shah said that Government led by Shri Bommai is crediting Rs. 1,250 crore annually through DBT to the accounts of milk producing farmers and also to remove malnutrition among children through the Ksheer Bhagya scheme, milk is being provided to 65 lakh children in 51,000 government schools and 39 lakh children in 64,000 Anganwadis .Shri Amit Shah congratulated the Chairman of Mandya Milk Producers Committee for his efforts to increase the income of all the farmers of Mandya district through dairy.


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- In its first acquisition, Harry's on Monday announced it has purchased Lumē Deodorant, a DTC brand focused on managing body odor, for an undisclosed amount. The deal is expected to close by the end of the year, subject to customary closing conditions.
- Lumē was founded on the idea that all body odor has the same root cause, and its mission is to normalize the problem and provide product solutions to it, according to a company press release.
- Harry's innovation arm, Harry's Labs, was responsible for the acquisition. Harry's Labs has also launched several brands under Harry's over the years, including razor brand Flamingo, pet brand Cat Person and hair care brand Headquarters.
While Harry's made its name as a DTC shaving brand, the company has moved beyond its roots since then.
In addition to expanding its own product offerings to include hair care, deodorant and other items, Harry's has also entered other markets by launching entirely new brands. In 2018, Harry's debuted its women's shaving and body care brand, Flamingo, a seemingly natural extension from its core business. Since then, the company has branched out further, launching pet brand Cat Person in 2020 and hair care brand Headquarters at the start of the year.
Although the purchase of Lumē itself was unknown prior to this week, Harry's earlier this year made it clear that acquisitions were on the horizon. In March, the company raised $155 million in a Series E round with the intent of adding more brands to its growing portfolio. At the time, the funding spiked Harry's valuation up to $1.7 billion.
"I am thrilled to partner with the team at Harry's at this point in our company's journey," Lumē's founder and CEO, Dr. Shannon Klingman, said in a statement. "They are proven experts in scaling omni-channel personal care brands and they deeply understand and support our mission to disrupt the odor control market."
Harry's appears to be well on its way to becoming its own DTC brand conglomerate, a trend that is emerging more in the space as direct-to-consumer brands look for scale. As it acquires and incubates brands, Harry's is touting its support for founders through expertise in brand development, design, DTC marketing, sales and other spaces. Like others building up brand portfolios, Harry's is hoping that having a central infrastructure and "a community of fellow brand builders" will help the businesses scale.
While it seems to be focused on building out its own brands for now, Harry's had hoped to be acquired by Schick maker Edgewell in 2019. The deal fell through after FTC scrutiny, followed by the downfall of a similar deal P&G made to acquire women's shaving brand Billie.
While those particular acquisitions have come undone, large CPG companies have not been entirely unsuccessful in acquiring startups in the shaving space. Dollar Shave Club was notably acquired by Unilever in 2016 for $1 billion, and just last month, Edgewell found success by acquiring Billie.


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We’ve all seen those exercise-obsessed air passengers who spend most of the flight walking up and down the aisle, doing deep knee bends and other movements designed to keep the blood flowing. Hell, on long haul flights I make a point of getting up a few times and doing some laps around the cabin.
Uma Thurman, of “Pulp Fiction” and “Kill Bill” fame, seems to take this to extremes, however.
Fametastic, a UK tabloid, reports that Thurman, heading to the Sundance Film Festival, recently spent a flight from New York to Salt Lake City doing yoga, stretching and dance moves up and down the aisle. She also reportedly used the plane’s back galley as her own private ballet studio, stretching and performing pliés for 20 minutes.