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The Chiefs Super 15 rugby team are running a “We Need your PJs” campaign and are calling upon Chiefs fans to donate new kids warm sleepwear, singlets and socks that will be given to patients at Waikids and families in need upon leaving Waikato Hospital.
Waikato DHB Child Health clinical unit leader Dr Dave Graham welcomed the special partnership between the Chiefs and the DHB.
“When you rush your really sick kid to hospital – and it’s often from a long way away – you’re not thinking about what you need when you go home. And you can’t get home to get them. That’s where the pyjamas, the singlets and the socks come in. We can help parents get their kids back home warm and getting better. It’s helping parents help their (Wai)kids.”
For those wanting to make a donation they are asked to drop off their new sleepwear, socks and singlets in any kids sizes to the Chiefs Headquarters or courier them to Chiefs Rugby, Bisley Road, Ruakura Research Centre, Hamilton prior to the 19th December 2014.
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Historic Home in Jefferson Park Threatened with Demolition
On Wednesday, October 28 the PLAN Committee of Denver City Council voted to put the designation of 2329 Eliot, the Anderson House, on the full council agenda. First reading will take place on November 9, and second reading, with a public hearing, will take place on November 16. Community members are encouraged to attend and speak at the November 16 meeting.
The committee vote followed the October 6 vote of the Landmark Commission, which found that the Anderson House meets the criteria for historic designation based on history and architecture criteria.
On Tuesday, October 6th, the historic designation application for the Anderson House will be heard by Denver's Landmark Preservation Commission. The role of the Commission is to decide if the structure has historical, architectural, or geographical significance. During this hearing, the public is encouraged to testify to the Commission on the historic merits of the building, and its value to the community.
If the Commission approves the application, it will head to the Neighborhood and Planning subcommittee of City Council before being heard by the full City Council.
If you would like to attend the public hearing for this important home, plan to be at the Wellington Webb Building on Tuesday, October 6th!
Anderson House Hearing
1:00 p.m. Tuesday, October 6th,
201 W. Colfax Ave
On June 16th, the developer filed a lawsuit against the city of Denver to stop the designation from moving forward. However, on August 14th, Denver Judge Bruce Jones ruled in the favor of the City of Denver, declaring that the Office of Community Planning and Development was correct in accepting a historic designation application from incoming councilman Rafael Espinoza. While Judge Jones has dismissed the lawsuit, he has not yet lifted the stay on the designation application, meaning that it has not begun the public hearing process. When the judge does lift the stay, the application will go before the Landmark Preservation Commission for a public hearing, before advancing to city council.
Jefferson Park neighbors are currently gathering signatures to show public support for the designation of this important structure. You can learn more about their efforts and sign the petition HERE
Stay tuned for more information as we await further information from the city, including a timeline for the public hearing process. Historic Denver will provide updates here on our website and on our Facebook Page
On April 17th 2015, the City of Denver received two Certificates of Non-Historic Status for 2329 and 2331 Eliot Street. Both structures date from the late 1880s to early 1890s. The demolition review procedures require that the City post any property for which a Certificate of Non-Historic Status or a Demolition permit has been submitted, and that has the potential for historic designation, a property that can meet at least two out of the three categories for designation, history, architecture and geography. Because The Anderson House can meet these criteria, a 120-day process began. 2331 Eliot was deemed to be ineligible for historic designation, but its neighbor at 2329 Eliot was found to have both historical and architectural significance.
This home, known as the Anderson House, was the home of William W. Anderson, a prominent lawyer in Denver. His fame and notoriety came not from his law practice, however, but due to an altercation with Denver Post owners and editors, H.H. Tammen and F.G. Bonfils on January 13, 1900.
Anderson was associated with one of Colorado’s most infamous residents — convicted cannibal, Alfred Packer. Alfred Packer led 5 prospectors in search of gold into the mountains in 1873 and was the only one to return. He was accused of cannibalism and sentenced to 40 years in the Cañon City jail for murder. At the time, this was the longest custodial sentence ever handed down in the State of Colorado. Anderson hoped to appeal Packer’s case based on a legal technicality and met with Packer to discuss the idea, at which point Packer provided Anderson with some funds. The Denver Post publishers, F.G. Bonfils and H.H. Tammen, who were also interested in Packer's case, accused Anderson of taking Packer’s life savings as a retainer. After Anderson went to the Denver Post offices to discuss the matter, a heated debate turned to fisticuffs, and Anderson shot Bonfils and Tammen in their Denver Post office in front of a witness, the reporter known as Polly Pry. Anderson was tried three times for assault with intent to murder, but was never convicted. During Anderson’s third trial, Bonfils and Tammen were convicted of jury tampering. Anderson lived in his home at 2329 Eliot Street from 1897 to c1904 and again from 1915 until his death in 1930. When detailing the shooting and the trial, the Denver Post even published his address with a note that he lived there with his wife and their three children.
Historic Denver became active in the ongoing effort to save this structure when members of the community reached out to us, hoping to learn more about the house and its history. Three community members submitted a historic designation application on May 28th. The designation application was judged complete by the staff of the Landmark Preservation Commission. This means that the application will go before the Landmark Preservation Commission. At this commission meeting there will be a public hearing so that members of the community may comment on the significance of the house. The Commission will then determine whether or not the house meets the criteria for landmark status. The application, if approved, moves to a Council Committee and then ultimately to City Council for a public hearing and a full vote.

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domain: food


Presentation on theme: "Fundraiser Management, Deposits, Controls, and What about Sales Tax?"— Presentation transcript:
Fundraiser Management, Deposits, Controls, and What about Sales Tax?
Student Fundraising Policy District-Sponsored Fundraising - Any activity that has the purpose of raising funds in support of a student activity or program and that is administered and conducted by school staff or students involved in the activity or program.
Student Fundraising Policy cont… The Board prefers that the school district financially support district-sponsored student programs and activities. However, in some cases it may be necessary to raise funds to help support these district endeavors, and the district may involve students in these fundraising activities. The superintendent and/or administrators will be directly responsible for all district- sponsored fundraising activities conducted in the district or sponsored in any manner by the district. School organizations MAY BE LIMITED to a maximum of number of fundraisers. All district-sponsored fundraising activities must first be approved by the building administrator and/or the superintendent or designee and must comply with the requirements set out in district policies and procedures, including the district's wellness program and district funds management rules.
side note - District's Wellness Program…. Did you know….. New obligations under the new free and reduced lunch regulations. Limitations for selling fundraising food to students during the school day. Food sold to students must meet nutrition standards unless DESE exception New Obligations !!! Each school can sell food that does not meet nutritional standards during the school day for a total of five days a year. Band sells candy bars during the school day…allowable for five days only!! This is the only non-nutritional food sales that can occur in that building during the school day in that year!! Exception!!!
back to - Student Fundraising Policy cont… Student-Initiated Group Fundraisers Student-initiated groups are not district sponsored, but these groups have the same access to district facilities, communications channels and fundraising opportunities as other district-sponsored non- curricular groups. These groups may conduct fundraising activities, but must follow the same rules applicable to other district-sponsored non-curricular groups. Fundraising by Other Groups For liability and funds management purposes, it is essential that district staff not confuse district- sponsored fundraising with fundraising conducted by booster clubs or other groups not directly controlled by the district. cannot take responsibility for fundraising or the funds collected by such groups. To avoid confusing parents, students and community members participating in the fundraising efforts, only district-sponsored fundraising subject to district rules should occur during the school day or class time. A group may only use the name, logo or mascot of the district or of a district school in reference to a fundraiser if the fundraiser has been approved by the superintendent or designee or the School Board and the funds raised go to the district as represented in the advertising.
Fundraising Approval Procedure Approval Form MUST be completed prior to scheduling a fundraiser or ordering merchandise for a fundraiser. FUNDRAISING APPROVAL FORM This form must be completed and returned to building administrator for approval at least one (3) weeks prior to scheduling and/or ordering merchandise for a fundraiser. ______________________ __ ________________ Name of Club/Organization Name of Sponsor _____________ Date of Request ______________________ ___________________ GL Expense Code Type of Fund Raising Purpose:_______________________________________________________ ______________________________________________________________ _________________________________________ _________________ Vendor / Salesperson Phone# Estimated Total Revenue: $_____________ Estimated Total Payment to Vendor $_____________ Est. of Other Costs Incurred and Explanation: ____________________________________________________________ ____________________________________________________________ _______________________ ____________________ Requested Delivery Date Actual Date of Delivery _______________________ _____________________ Person Accepting Delivery _______________________ Week of Sale Week Money to be Collected _______________________ ________________________ Sponsor Signature Building Admin. Signature This fundraiser has been approved / disapproved (circle one) on the following date _______
Requirements for Fund Raiser Approval A worksheet is available (if needed) to calculate the Estimated Revenue and Expenditures. The worksheet does NOT need to be attached to this form. 1.Complete “Fundraiser Approval Form 2. Administrator must approve the contract/agreement between the fundraising company and the sponsor and a copy a. Scanned to Accounts Payable as support for requisition/purchase order. b. Filed with building administrator. 3.Fundraiser placed on building calendar. 4.A copy of fundraising guidelines to be given to the students. 5.Checks must be made out in building name or MVR-III School District; no other checks will be accepted. 6.Students are not to coordinate fundraising monies. This is the sponsor’s responsibility. 7.Deposits turned in daily and initialed by secretary. Fund raiser # MUST be recorded on deposit form. 8.All accounts monies/merchandise must be collected and turned in within one (1) week of end of sale.
Fundraiser Worksheet Worksheet is available (if needed) to calculate the Estimated Revenue and Expenditures. The worksheet does NOT need to be attached to fundraising form.
Deposit Controls This procedure applies to all district employees who collect money regardless of whether that activity takes place on or off campus. Method of Payment 1. Checks are the preferred method of payment for all school activities. Other acceptable methods of payment include cash and money orders. All checks and money orders should be made out to the building name or to Meramec Valley R-III School District. 2. Cleared checks will provide proof of payment for any non-cash payments. 3. For payments made in cash, the payer may request a written receipt from the teacher, sponsor or other school personnel. Personnel will provide a receipt upon request.
Deposit Controls cont…. Proof of Receipt 1. All monies (cash, checks and money orders) collected by personnel other than the building secretary must be turned into the building secretary daily, accompanied by daily tabulation of receipts form. 2. Submit all money to the secretary in the same form as collected. 3. Never cash or substitute personal checks with cash collections. 4. Do not hold or accept pre- or post-dated checks. 5. Do not deposit money in personal checking accounts or bank deposit boxes. 6. Do not spend any of the collections. All payments must be made utilizing the Board approved purchase process.
Deposit Controls cont… Deposits All checks will be endorsed by the building secretary “For Deposit Only.” Individual deposits consisting of $300 in cash or coin (does not include total of checks) WILL NOT be sent via transportation or inter-office district mail but will be delivered to the depository institution by the building principal or designee. Receipts will be taken intact directly to the depository institution for deposit in the applicable checking account. Deposits shall be made the same day as received, if possible and recorded in the accounting system. Use the daily tabulation of receipts form. A listing from the accounting system shall be compared to the bank statement entries, thus assuring that all monies are deposited.
Deposit Controls cont… Deposits - D aily tabulation of receipts form.
A specific fundraising example we all can relate to?
MVR-III Book Fair’s Accounting & Reporting Procedures Prior to Book Fair When the book fair is approved, but not less than 3 weeks prior to the fundraiser start date, building/program will submit a purchase requisition for estimated amount of payment to the book fair vendor, including in comments “do not send to vendor”. Also send a copy of any contract or agreement along with the supporting “Fundraising Approval Form” form to accounts payable. Request Starter Change Check book fair tool kit for suggested number of registers and the amount recommended per register, not to exceed $75 per register. If change is needed, contact business office bookkeeper for requisition requirements/GL code. Submit a requisition not less than three weeks prior to the book fair start date, indicating sales start date and denominations needed. At the close of the fair, additional starter change must be re-deposited into the same GL code used to submit the requisition.
Book Fair Accounting & Reporting Procedures During Book Fair Clear registers before fair begins. Establish a cash drawer for each register. Count to verify starter amount of starter change received prior to opening fair each day/session. Lock cash drawer per device procedures. Do not leave cash drawer open unattended. Room should be locked should book fair manager/volunteers need to leave the room for a brief period. Sales Follow company procedures for processing voids. Maintain a manual list of all voids. Maintain a list of all register restarts, noting date and time. Accept payment for amount of sale only, ie do not accept payment for more than purchase and do not cash checks. Money orders and cashier checks are processed as checks.
Book Fair Accounting & Reporting Procedures Daily Close of Book Fair Run the following book fair reports from each register: Daily financial summary & sales detailed report Count and set aside amount of daily starter change in denominations needed for the next day/session. Count all funds in the drawer…checks, currency and coin…and complete form DI- AF1, attaching a copy of each register’s financial summary. Totals for each type of collection along with total submitted are acceptable on form DI-AF1. Balance cash drawer at close of each day/session. Best practice is to have two persons count and verify the sales deposit and the starter change. Turn in all sales money collected to office daily for deposit, as directed by building/program administrator, along with completed form DI-AF1 and attached daily sales report. Turn in starter change for safekeeping until the following day/session. Record daily sales on the sales report each day.
Book Fair Accounting & Reporting Procedures Close of Fair Re-deposit starter change as applicable, using the GL code from the requisition request. Total daily sales report. Run total fair financial summary report from each register. Attach to daily sales report. Submit daily sales report and financial report to the building administrator.
What about Sales Tax? Exempt: “All sales made by or to religious and charitable organizations and institutions in their religious, charitable, or educational functions and activities and all sales made by or to all elementary and secondary schools operated at public expense in their educational functions and activities;...” §144.030.2(20), RSMo. Public Schools are Exempt from State and Local Sales and Use Tax
Sales Tax Example (G) A parent teacher organization (PTO) agrees with a candy company to sell candy as a fundraiser for a public elementary school. The PTO buys the candy from the company and has the right to return any unsold candy over the minimum agreed amount. The sale is not subject to tax because the PTO is the seller of the candy and its sales are exempt from tax as sales by a public elementary school. 12 CSR 10-103.210
Sales Tax Example (H) A parent teacher organization agrees with a wrapping paper company to sell wrapping paper as a fundraiser for a public elementary school. The PTO takes orders for the wrapping paper and forwards the orders to the company. The PTO never takes title to the wrapping paper—it merely takes the orders and delivers the paper. The company must collect and remit tax because the company is the seller of the wrapping paper. 12 CSR 10-103.210
Do You Collect Sales Tax at the Book Fair? Unless the district buys the books and resells them – yes! Problem: Have you been? Scholastic Agreement: “Collect sales tax as required by your state law as purchases of books and educational material from SBF are for resale.” Concern: District is on the hook for the sales tax
Bottom line??? review, review, review, REVISION!!! Review current Board policies for guidance and support. Review current procedures. Review for changes, internal and external. Revision is imminent! Education is constantly changing! Use your resources. Use your peers!
THE END Slides and all supporting policy, procedure and forms will be posted on www.MoASBO.org Susan Goldammer Senior Director, Employment and Labor Relations Missouri School Boards' Association 2100 I-70 Dr SW, Columbia, MO 65203 p: 573-445-9920, ext. 355 | c: 573-489-0338 firstname.lastname@example.org Diane Winters Financial Analyst Meramec Valley R-III School District 126 N Payne Street, Pacific, MO 63069 (636)271-1400 ext. 1007 email@example.com


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Department of Neurology
University Hospital Zurich
Tel. +41 44 255 5500
Fax +41 44 255 4507
Keywords: neurooncology, glioblastoma, immunotherapy, angiogenesis, cancer stem cells
1 group leader, 2 MD scientists, 2 postdocs, 3 PhD students, 2 technicians
Despite multimodal treatment, the prognosis for patients with malignant gliomas remains poor. Our immunotherapy projects aim at defining the basis for a novel immunotherapeutic approach targeting glioma-initiating cells with stem cell properties, commonly named glioma stem cells. These glioma stem cells are isolated from surgically removed tumor material and characterized for possible immunogenic properties with a focus on cell surface markers for immune recognition. The susceptibility of glioma stem cells towards an attack of immune effector cells in vitro and in vivo is examined, with the hope to develop novel approaches of tumor stem cell-specific vaccination against brain tumors. The Brain Tumor Center Zurich participates in the first phase III clinical trial of vaccination for glioblastoma patients with EGFRvIII-mutant tumors (ACT IV).
There is emerging evidence that gliomas just like other tumors exhibit a hierarchic structure of cellular composition. Glioma stem cells are defined as less differentiated, multipotent and highly tumorigenic cells with self-renewal capacity. These cells form neurospheres under defined conditions and express markers of stem cells such as CD133 or nestin (see Figure). The glioma stem cells are thought to maintain tumor growth, and there is evidence that they might confer resistance to conventional radio- and chemotherapy. To explore this novel look at cancer resistance, glioma cells with and without stem cell properties will be compared regarding their resistance mechanisms to irradiation and currently used cancer chemotherapeutic agents.
The major focus of clinical research in Neuro-Oncology is currently on inhibiting angiogenesis using various pharmacological strategies. Here the Department of Neurology together with its clinical partner institutions in Zurich, within the Brain Tumor Center Zurich, is currently involved in various multicenter trials, e.g., by the European Organization for Research and Treatment of Cancer (EORTC) or initiated and led by Zurich, e.g., the ARTE trial on radiotherapy without or with bevacizumab for elderly patients with glioblastoma. In parallel, in a translational approach, using cell culture and animal models with innovative small animal imaging, we try to understand the signaling emanating from and to glioma cells in the context of angiogenesis and escape from anti-angiogenic strategies.
All standard methods of biochemistry, cell and molecular biology are used in our laboratory, e.g., real-time PCR, immunoblot, apoptosis and proliferation assays, cell cycle analysis, transfection techniques, siRNA technology, and immunological assays. We also use different in vivo rodent glioma models and in vivo glioma imaging in mice.
Departments/Institutes of Neurosurgery, Neuroradiology, Neuropathology, Oncology, Radiation Oncology and Nuclear Medicine, University Hospital Zurich and University of Zurich USZ/UZH
Department of Neurooncology, Heidelberg, Germany
Biochemistry, Regensburg, Germany
Institute for Molecular Biology, Essen, Germany
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Rick Springfield remains devoted to his fans
Rick Springfield is always tinkering with his set list.
He has no choice due to his ardent fans.
The former pin-up, who rocketed to stratospheric heights during the ‘80s, still has a devoted number of fans who catch a bunch of his shows each year, purchase rarities and act as if it’s still 1984.
For proof, check out the forthcoming documentary, “An Affair of the Heart: The Journey of Rick Springfield and his Devoted Fans.”
The film, which will hit screens later this month, is about the three-decade-old connection between Springfield and his loyal fans.
“I’ve been incredibly fortunate,” Springfield says while calling from his Los Angeles home. “A lot of music fans move on to someone new, whatever the flavor of the month is, but I have an incredible base of fans who have continued to support me after many years. I’m very thankful for that.”
Springfield, 62, feeds off his faithful followers’ unbridled enthusiasm.
He could coast on ‘80s hits such as “Jessie’s Girl” and “Hard to Hold,” but he continues to craft new material.
“There’s a demand for it and I love to write,” he says. “Writing is one of my favorite things to do. I always look forward to it. I have to knuckle down soon and write a new record. It’s all about writing and recording and touring.”
Springfield, who will perform Friday night at the Borgata, has added a few new wrinkles on this tour.
“We put in a medley of a bunch of hits we weren’t doing,” he says. “It pleases the fans.”
Count on full versions of “Jessie’s Girl” and the hit “I’ve Done Everything For You.” Many critics wrote off those songs as trifles during the Reagan era, but the power-pop gems have certainly held up.
“It doesn’t surprise me that they stood the test of time,” says Springfield. “I always thought they were well-constructed songs. I put everything I have into my songs.”
Part of his appeal is that many of his songs appear to come straight from the heart. Such cuts as “My Depression,” which was inspired by his suicidal tendencies as a teenager, and “My Father’s Chair,” which was written for his late dad, are from his personal experience.
“I think the best songs come from there,” Springfield says. “So many things move me. That’s how I write and I’ll continue to write.”
Rick Springfield appears Friday at the Borgata, 1 Borgata Way, Atlantic City. Show time: 9 p.m. Tickets: $55 and $60. Information: 609-317-1000.

domain: entertainment


text: One Love Design House is a full service design studio, showroom, retailer, and production space in the heart of Charleston, SC. Every gown is handmade by our team of skilled artisans and brides have the unique opportunity to see and feel the materials as each piece is being made. Clients can shop gowns in our current collection, or make any customization they desire. We will tweak a style from our showroom or start from scratch with a custom design. The One Love bride is adventurous, free spirited and always guided by her heart.

domain: artistic


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We know that getting in those rays of sunshine or taking that vitamin D supplement is good for our bones, mood and overall health – and now – researchers may have found a link between the sunshine vitamin and COVID-19.
Two separate studies have shown negative correlations between vitamin D levels and COVID-19-related mortality in severe cases of the infection. According to the studies, people with vitamin D deficiency who develop severe COVID-19 complications may have a higher risk of dying from the disease.
In the body, vitamin D is produced in the skin from exposure to UVB sunlight. The micronutrient increases calcium and phosphorus absorption from food to help maintain strong bones and teeth, as well as stimulate immune responses.
Examining Factors Related to COVID-19 Mortality
In one of the studies, researchers from Northwestern University used publicly available data from around the world and uncovered a strong association between severe vitamin D deficiency and COVID-19 mortality rates.
The research team analyzed data from hospitals and clinics across China, France, Germany, Italy, Iran, South Korea, Spain, Switzerland, the United Kingdom (UK) and the United States (US). They found that patients in countries with high COVID-19 mortality rates, namely Italy, Spain and the UK, had lower vitamin D levels than patients in countries with low mortality.
Results of the research study are available on medRxiv, which is a preprint server for health sciences.
The Northwestern researchers became interested in conducting their study after noticing unexplainable differences in COVID-19 mortality rates between countries. While factors such as quality of healthcare, age and testing were seemingly plausible, differences in mortality were present even in patients within the same age group.
Lead researcher on the study, Dr. Vadim Backman, a Professor of Biomedical Engineering at Northwestern’s McCormick School of Engineering was convinced that age or quality of healthcare did not play a role in the observed mortalities.
Quoting Backman from statements he provided to Northwestern University, he said that, “The healthcare system in northern Italy is one of the best in the world. Differences in mortality exist even if one looks across the same age group. And, while the restrictions on testing do indeed vary, the disparities in mortality still exist even when we looked at countries or populations for which similar testing rates apply.”
Backman and his team therefore decided to dig deeper and through their global data analysis, found strong correlations between vitamin D levels, mortality and ‘cytokine storm,’ which is a hyperinflammatory condition in which immune cells release large amounts of cytokines. Levels of C-Reactive Protein (CRP), an inflammatory marker, were used as an indicator for this potentially deadly condition.
In cytokine storm, the immune system is overactivated and this can cause severe damage to lungs, leading to acute respiratory distress and death.
Dr. Ali Daneshkhah, a postdoctoral research associate in Backman’s laboratory and first author on the study paper explained that, “This is what seems to kill a majority of COVID-19 patients, not the destruction of the lungs by the virus itself. It is the complications from the misdirected fire from the immune system.”
Vitamin D plays a significant role in both enhancing the innate immune system, as well as keeping the adaptive/acquired immune system in check, preventing it from becoming overactive. Vitamin D could therefore be protective against complications resulting from cytokine storm, and ultimately death, in severe COVID-19 infections.
“Our analysis shows that it might be as high as cutting the mortality rate in half,” said Backman. “It will not prevent a patient from contracting the virus, but it may reduce complications and prevent death in those who are infected.”
Backman also said this association could help explain why children are less severely affected by COVID-19 and much less likely to die from the disease. This is because children do not have a fully developed acquired immune system, which is what in all likelihood, becomes overactivated to cause severe complications from COVID-19.
While the results from the study are insightful, more research is needed to decipher how vitamin D actually functions in a protective role against complications arising from COVID-19. Therefore, it is not advisable to take large doses of it as excess amounts can cause significant negative side effects.
“It is hard to say which dose is most beneficial for COVID-19,” Backman said. “However, it is clear that vitamin D deficiency is harmful, and it can be easily addressed with appropriate supplementation. This might be another key to helping protect vulnerable populations, such as African-American and elderly patients, who have a prevalence of vitamin D deficiency.”
Vitamin D and Coronavirus in European Populations
Another study also investigated vitamin D levels in COVID-19 patients and came to the same conclusions as the Northwestern study. It is important to note however, that both were correlative studies and therefore a causative link between COVID-19 mortality and vitamin D deficiency cannot be ascertained without further interventional or experimental studies.
Researchers in the UK evaluated levels of vitamin D across 20 countries in Europe and found that levels were extremely low in the elderly in Italy, Spain and Switzerland. This already represents the most vulnerable group of the demographic with regards to COVID-19.
In particular, patients in Italy and Spain, where COVID-19 mortality rates have been high, had lower average vitamin D levels than most northern European countries. Interestingly, people in northern European countries, including Finland, Norway, Denmark and Sweden, actually had higher than average levels of vitamin D and lower rates of COVID-19 cases and deaths.
In a press release, lead researcher on the study Dr. Lee Smith said, “Vitamin D has been shown to protect against acute respiratory infections, and older adults, the group most deficient in vitamin D, are also the ones most seriously affected by COVID-19.”
He added that, “A previous study found that 75 per cent of people in institutions, such as hospitals and care homes, were severely deficient in vitamin D. We suggest it would be advisable to perform dedicated studies looking at vitamin D levels in COVID-19 patients with different degrees of disease severity.”
The UK researchers also noted one of the caveats in the study was that differences in the level of testing and other public health measures across the different countries were not taken into account.
Moreover, neither study evaluated whether increasing vitamin D levels could result in better survival outcomes for COVID-19 patients. The researchers agree that this, and other questions pertaining to the mechanisms of vitamin D protection in COVID-19, warrant further study.
Importantly, there is no data to indicate that vitamin D may prevent COVID-19 . Therefore, researchers warn against using vitamin D for any other purposes than those prescribed by their physician.
Nevertheless, in places like Canada where much of the population is low in vitamin D, Canada advises year-round vitamin D supplementation for all Canadian adults. The organization recommends adults between the ages of 18 and 50 take 400 – 1,000 IU of vitamin D per day, and those over 50, or high-risk younger adults, take 800 – 2,000 IU daily.


- 1 Crucial Variables to think about When Buying a Stun Gun in Circleville New York for Personal Protection
- 2 Are Stun Guns Allowed Where You Reside in Circleville NY?
- 3 Is the Stun Gun you are Thinking about Purchasing in Zip Code 10919 Loud Enough to Scare Off an Attacker?
- 4 Can you Hide the Stun Gun Easily?
- 5 Can you conveniently get a hold of it when you need it for security from a Circleville-based opponent?
- 6 How Much Voltage Does A Stun Gun or Taser Typically Emit?
Crucial Variables to think about When Buying a Stun Gun in Circleville New York for Personal Protection
Many others pick devices like stun guns for their self defense functions. Keep reviewing to discover these critical questions to ask on your own about stun guns as you look over your choices.
Are Stun Guns Allowed Where You Reside in Circleville NY?
Self protection tools like stun guns do not deal with quite the degree of lawful analysis that actual weapons do, yet there are still often regulations and also guidelines bordering them. Certain stun batons and also gun may be limited as something you can have where you live.
Is the Stun Gun you are Thinking about Purchasing in Zip Code 10919 Loud Enough to Scare Off an Attacker?
Many individuals who get stun guns do not intend to ever before in fact run a million volts of electrical power through somebody. They just wish to be able to take out the device when confronted with a prospective enemy, and let them see and listen to the white warm electrical arc and also its thunder clap noise. While any stun gun should have sufficient juice to literally paralyze or control an individual enough time for you to leave to security, it ought to also put on sufficient of a show that the untrusted individual chooses to escape from you instead.
Can you Hide the Stun Gun Easily?
A stun gun is not likely something you want seen on you while you are out and also around in public. Protection guards and also law enforcement may also have concerns as well as conversations with you whenever they see you, also if the product in concern is lawful.
Can you conveniently get a hold of it when you need it for security from a Circleville-based opponent?
As long as you wish to hide a stun gun in order to avoid awkward minutes, responses, and even being prevented access from areas, you have to have the ability to draw it out as promptly and also easily as feasible when you need it. This is frequently done by either maintaining it near the top of the inside of a bag or potentially within a layer or jacket. There are a number of accessories on the marketplace that could be used to custom-create holsters you can make use of.
How Much Voltage Does A Stun Gun or Taser Typically Emit?
Along with stun gun holsters, a number of various other crucial self-defense items for ladies and also men consist of stun master stun batons, pink stun guns, mobile phone stun guns, tasers, technique pepper spray as well as runt stun guns. Some of these products product a considerable amount of charge.
Since you know the vital criteria to utilize in your search for a stun gun for self defense, you can find the right tool or gadget for your circumstance, place, as well as individual requirements.


Here’s our weekly review rounding up the best stories and ideas in public space from cities around the world. This week we bring you public spaces in Europe, putting Jane Jacobs to the test in Italian cities and the dollar value of urban trees.
Putting Jane Jacobs to the test
Jane Jacobs was put to the test in 6 Italian cities and she passed with flying colours. Jacobs proposed four conditions essential to vibrant city life. Researcher Marco De Nadai and his team at the University of Trento designed a way to test those conditions by mining databases and cell phone records in six Italian cities.(via Next City)
Public space in European cities
From regeneration and grassroots activism to privatisation and security, public space in Europe’s cities is shaped by a variety of urban developments. Guardian Cities asks how is the nature of public space in European cities changing? What’s improving and what’s getting worse? (via Guardian Cities)
The (dollar) value of urban trees
Free software program i-Tree uses GIS and a complex set of algorithms that allows communities and researchers to produce detailed inventories of their urban canopies, and calculate their dollar value.(via CityLab)
Photo by Pierre Metivier from Flickr CC


QUEZON CITY, May 6, 2016–The Information and Communications Technology Office of the Department of Science and Technology (DOST-ICTO) was one of the winners at the 2016 World Summitof Information Society (WSIS) Prizes. Their entry, the Tech4ED project, bagged the award in the e-Employment category, besting four other ICT applications from Colombia, Kuwait, Saudi Arabia and the United Arab Emirates.
The ICT Office’s Executive Director,Usec. Louis Napoleon C. Casambre, Deputy Executive Director for eSociety Bettina Quimson, Regional Director for Luzon Cluster 2 Cheryl Ortega and Regional Director for Mindanao Cluster 1 Maria Teresa MagadiaCamba accepted the distinction during awarding ceremonies held at the WSIS Forum 2016 in Geneva, Switzerland.
The WSIS Forum 2016 is the world’s largest annual gathering for the “ICT for Development” community. WSIS stakeholders established the WSIS Prizes to recognize organizations that showcase success stories and replicable models that empower the community at the local level. It pays tribute to the efforts of partners for their added value to society and their commitment towards achieving WSIS goals.
The ICT Office’s eSociety Division implemented the Tech4ED project, which stands for Technology for Education, Employment, Entrepreneurs and Economic Development Project. Tech4ED seeks to provide access to different aggregated, existing and proven ICT-enabled services and relevant content in one single platform. Tech4ED centers established throughout the country provide this platform to citizens, serving as a conduit for efficient delivery of government and other services.
Through the project, rural communities gain access to non-formal education, skills training, English training, an online library, ICT literacy, financial and entrepreneurial training materials and online government services.It is a potent tool for empowering and encouraging the participation of unserved and under-served communities, harnessing technology to create an inclusive, integrated and equitable countryside.
In 2015 alone, 89 new Tech4ED centers were established nationwide and 233 Memorandums of Understanding were signed with different municipalities and cities, paving the way for the creation of even more Tech4ED centers. Meanwhile, the first quarter of 2016 saw the inauguration of 14 new Tech4ED centers in Kapatagan, Lanao del Norte and 41 in Ilocos Norte.
The WSIS Prize contest comprises the 18 categories that are directly linked to the WSIS Action Lines outlined in the Geneva Plan of Action. Across these 18 categories, 88 organizations across the world were nominated.
According to the ITU, the United Nations specialized agency for information and communication technologies (ICTs), 18 projects were hailed “WSIS Prize Champions” out of 70 nominees from around the world. ITU Secretary General Houlin Zhao announced the prize for the Tech4ED Project during the WSIS High-Level Opening Segment in Geneva International Conference Centre (CICG). “ITU and its WSIS partners strongly believe in the critical importance of ICTs in achieving the 17 UN Sustainable Development Goals,” Zhao said.
“The WSIS Prizes recognize all players in the effort to improve global connectivity, from governments and global ICT companies to grassroots NGOs leading innovative ICT-oriented projects at the local level. All of these stakeholders are equally vital to the success of the WSIS Process,” Zhao added.


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RICHARD DUNNE is the notable absentee from the 27-man squad for the upcoming friendlies against Latvia and Poland, Martin O'Neill and Roy Keane's first test as the new Ireland management team, writes PAUL HYLAND.
As Noel King's final act as interim boss, he included Stephen Ward, out in the cold during the final days of the Trapattoni era, and returnees Andy Reid and Anthony Stokes.
QPR defender Dunne (above) will not join up with the squad and will instead continue his recovery from the groin problem which sidelined him for the whole of last season.
Newcastle goalkeeper Rob Elliot retains his place and Reading's Alex Pearce is the big winner, an obvious replacement for Dunne.
O'Neill and Keane will hold their first training session with the players in Malahide on Monday.
Goalkeepers: David Forde (Millwall), Keiren Westwood (Sunderland), Rob Elliot (Newcastle).
DEFENDERS: Sean St Ledger (Leicester), Marc Wilson (Stoke), Seamus Coleman (Everton), John O'Shea (Sunderland), Alex Pearce (Reading), Stephen Kelly (Reading), Joey O'Brien (W Ham).
MIDFIELDERS: James McCarthy (Wigan), Ciaran Clark (Aston Villa), Stephen Ward (Brighton); Glenn Whelan (Stoke), Paul Green (Leeds), Andy Reid (Nottingham Forest), Aiden McGeady (Spartak Moscow), Anthony Pilkington (Norwich), James McClean (Wigan), Robbie Brady, Stephen Quinn (both Hull), Wes Hoolahan (Norwich City).
STRIKERS: Shane Long (West Brom), Robbie Keane (LA Galaxy), Jon Walters (Stoke), Kevin Doyle (Wolves), Anthony Stokes (Celtic).


text: Now for the fun part! It’s time to pick out paint colors, tile, floor coverings, light fixtures, cabinets, countertops, doors, trim, knobs…are you feeling overwhelmed yet? Not only is there a lot to think about, but the options are endless! We’ve had months of daydreaming trying to decide between the perfect blend of trendy yet timeless. I have always been obsessed with light fixtures. The one thing I knew I wanted for sure was the Hundi Metal Glass pendent from Pottery Barn for the dining room. Do you remember the Kohler commercial when the woman set a bathroom sink faucet on the table and said, “Design a house around this.” That’s how I feel about this light. I figure it must be pretty timeless because they’ve been selling it for years now. I also knew that I wanted a fun black and white tile for the laundry room. I absolutely love blue, gray and white paint colors, hard wood flooring and granite countertops. Here’s a glimpse of some our color choices. I can’t wait to see how it all turns out! If you would like help designing your dream home, call Averie Construction, LLC today at 605-890-9795. We look forward to working with you!


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She spoke softly tonight, words skipping off a pond in silence, her voice reaching me in the resulting ripples. I kept my arms folded to distance my thoughts from becoming possible urges for my hands to act upon. To pull her body close, brush her warm skin against mine with a slight breath onto her neck as I moved in close to place my lips near her cheekbone.
Urges like that.
Words slowed to a pause before starting our goodbyes.
Staring at the faint ridges of her face, “Oh I could give you a hug. It’s not that weird for me.” I glanced downward hoping to slide off the lie.
“It's just that the hugs always led to kisses and then...”
I stepped up and gave her a hug, well aware that at one time I would’ve kissed her ear and pulled her inside the house with me. Now these thoughts just hover above us, safely out of reach.
One of us said something that started up the conversation again, this time about how long one would wait to hear their partner to say I love you. She set April as the deadline for her current situation, so typical of her black and white way of thinking.
"You have a deadline on everything?" I asked.
"Well yeah, I had a deadline on how long it was going to take for him to say we were going out officially." Three months as not to rush him, but it only took him three days she happily reported.
"So When April comes around and he doesn't say it, you're going to?"
"Yes I am."
I gave a look of disbelief at first. She must be realizing how into him she was to commit to such an act. For a girl who formulated escape plans, cover stories, and plausible deniability in case her hopes were thwarted, she had to be damn confident in a successful outcome.
She mentioned that she didn't have a set plan of attack formulated yet so I told her how I would do it as a guy in that position.
I explained the prepping would start with a slow build up of goodbyes taking a few seconds longer each week. The actual engagement would start as a standard kiss and I'll see you later as usual but as I stepped back a couple feet, I would turn back, rush up to her ear and whisper I love you. As quickly as I pounced I scatter away with a smile leaving her hopefully dumbfounded.
I demonstrated my sample attack on her.
I could've attacked.
I kept talking past the look she gave afterwards, my body discovering gravity again as I felt pulled back into my leaning position against the trunk. That knotted feeling in my stomach returned to end our conversation a few minutes later, my sample attack was taking me out internally.
"You should go."
"Oh you're kicking me out now?" She smiled knowingly.
"You need to go"
I remain attached to my car as she pulled out and waved goodbye. Out of sight I stumble in to the house hitting the garage door button before entering.
My stomach ached.
The couch and comforter welcomed me.

domain: literature


text:
Medications play a crucial role in maintaining and improving our health, but it is essential to use them responsibly to ensure their safety and effectiveness. Taking medication responsibly involves more than just taking the prescribed dosage; it requires understanding your medications, following guidelines, and making informed decisions.
In this article, we will explore the importance of proper medication management and provide practical guidelines and tips to help you use medicines wisely.
Before starting any new medication, discuss your medical history, allergies, and current medications with your healthcare provider. This information will enable them to prescribe the most appropriate medication and dosage for you.
Once you receive your new medicine, be sure to familiarise yourself with and understand the medication label, including the dosage instructions, warnings, and potential side effects. If you have any questions or concerns, speak with your doctor.
While medicines are developed to help, they can cause problems when not taken correctly, including the following.
Some medications can cause adverse reactions and side effects and this is particularly true when they’re not used responsibly. Taking medications without proper medical guidance may lead to allergic reactions, organ damage, or life-threatening complications. This may be due to the wrong dosage, a person’s individual sensitivities, or because of interactions with other drugs.
Combining medications without proper knowledge of potential drug interactions can be extremely hazardous. Certain combinations can amplify or diminish the effects of each medication, leading to unintended consequences.
For example, ibuprofen, a common painkiller, shouldn’t be taken while also taking warfarin, a popular anticoagulant, as there is a greatly increased risk of serious bleeding complications, due to both medicines’ blood thinning properties.
Irresponsible use of antibiotics and antiviral medications has contributed to the growing problem of drug resistance. When medications are taken inappropriately, such as incomplete courses of antibiotics or using them for non-bacterial infections, bacteria and viruses can adapt and become resistant to the drugs. This jeopardises the effectiveness of these medications, making it harder to combat infections and diseases.
Irresponsible medication use, particularly self-medication without professional guidance, can mask underlying health issues. Medications may alleviate symptoms temporarily, giving a false sense of improvement while the underlying condition worsens. Delaying proper diagnosis and treatment can lead to complications, progression of diseases, and missed opportunities for early intervention.
Certain medications, such as opioids, sedatives, and stimulants, have a high potential for dependence and addiction. Irresponsible use, such as exceeding prescribed dosages or using medications without a legitimate medical need, increases the risk of developing a substance use disorder. Substance misuse not only harms individuals but also impacts their relationships, work productivity, and overall quality of life.
Always follow the prescribed dosage, unless advised otherwise by your doctor. Taking too little may result in insufficient treatment while taking too much can lead to adverse effects or toxicity. Follow the recommended schedule and duration of use.
Incorporate your medication into a daily routine to help ensure consistency. Consider using pill organisers or phone reminders to avoid missed doses.
Store medications in a cool, dry place away from sunlight and moisture, or otherwise as specified on the label. Dispose of expired or unused medications properly, following local guidelines to prevent accidental consumption.
Medications prescribed to you are tailored to your specific needs. Even if the symptoms appear similar, sharing medications can have adverse consequences and may not provide the desired benefits.
Inform your healthcare provider about any herbal supplements, vitamins or over-the-counter medications you are taking. Some substances can interact with prescribed medications, leading to potential side effects or reduced efficacy.
Be aware of potential side effects and monitor your body’s response to the medication. Report any unexpected or severe side effects to your healthcare provider promptly.
Self-diagnosing and self-medicating can lead to incorrect treatments or masking underlying conditions. Always seek professional medical advice before starting or changing any medication.
If you or someone you know has a dependence on pills or other medications, we can help. Here at ANA Treatment Centres, we specialise in providing therapies for addictive behaviours. Get in touch today to find out how we can help.


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PUERTO Pollensa is the only Majorca resort which has made its way on to a list of the top 10 favourite holiday destinations of British tourists in a survey by a UK travel company.
The poll by Thomson, part of the Tui Travel group, compiled thousands of customer reviews as a guide for people planning to head away on holiday this summer.
Long-term favourites like Palmanova, Cala D'Or and Alcudia failed to show in the top 10 which will come as a blow to Majorca tourism bosses who have earmarked a small fortune to promote the island as a holiday destination.
Results showed that Benidorm was the favourite package holiday resort. The Costa Blanca destination topped the list of holidaymakers' favourites having cleaned up its lager lout and chips-with-everything image built up over the last 20 years.

domain: travel


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Abstract 17977: Serial Gene Expression Changes Associated With Reverse Remodeling in Dilated Cardiomyopathies: Results of the Effects of Beta-Blockers on Remodeling and Gene Expression in the Failing Human Heart (BORG) Trial (NCT01798992)
Background: We have previously reported that when β-blocking agents produce reverse remodeling on nonischemic dilated cardiomyopathies (NDCMs) they effect a partial reversal of changes in constituents of the classic fetal-adult contractile protein (CP)/natriuretic peptide (NP)/SR Ca2+ ATPase (SERCA2a) gene "program". The objective of the current study was to characterize changes in myocardial gene expression among other contractile, signaling, and metabolic pathways that may be associated with reverse remodeling in NDCMs.
Methods and Results: We measured the mRNA expression of 50 genes by quantitative PCR in RNA derived from RV septal endomyocardial biopsies done at baseline and after 3 and 12 months of β-blocker treatment. Forty-seven NDCM patients (mean baseline LVEFs 24+9%, RVEFs 27+9%) were randomized to metoprolol CR/XL, metoprolol + doxazosin, or carvedilol for 18 months, and myocardial gene expression was measured at baseline and after 3 and 12 months of treatment. Thirty-seven patients had reverse remodeling responses by 12 months, defined by change in LVEF (n=30, Δ=23±9%) and/or RVEF (n=28, Δ=16±2%). Previously described decreases in ANP, BNP and increases in α-MHC, SERCA2a, PLN, and RYR2 were again associated with reverse remodeling. In addition, increases in α1A-AR, β1-AR, VLC1, and m-CPT1 were associated with LVEF response, increases in α1A-AR, AT-1R and decreases in β-ARK1, PKC-β, HxK2 and IL-6 were associated with RVEF response, and increases in α1A-AR and AT-1R and decreases in ACTA1, prepro-ET, IL-6, and NHE-1 were associated with biventricular response compared to non-responders.
Conclusions: In addition to previously described changes in CP, NP, and SERCA2a myocardial gene expression, a number of additional calcium handling, sarcomeric, neurohormonal, adrenergic signaling, and metabolic genes are associated with ventricular reverse remodeling. These additional genes may provide further insight into the primary regulatory mechanisms involved in β-blocker mediated reverse remodeling.
- © 2013 by American Heart Association, Inc.

domain: biology


text:
Pigeon Forge Tribute Show Package
The Pigeon Forge Area of Tennessee is renown for its amazing things to do and quality entertainment.
With four nights of lodging at your choice of hotels, guests will be able to ensure that their time is spent relaxed and comfortable. Whether you want to enjoy a free continental breakfast, an indoor pool, or a fantastic location, you are sure to find something to your liking.
Also included is the Tribute to Conway Twitty Show. Join performer Travis James as he brings to life the music and essence of country music legend Conway Twitty. With songs like 'Hello Darlin'', 'I Can't Love You Enough', and 'After the Fire is Gone', you're sure to have an amazing time dancing and singing along.
Brian Hoffman's Remembering Red is also included in the package. This tribute show encompasses the amazing persona of Red Skelton with fantastic comedy and skits. This show is perfect for all ages, but especially for those who grew up watching his pieces.
This vacation package makes it easy to enjoy the great entertainment of Pigeon Forge, TN. Get four nights of lodging as well as tickets to A Tribute to Conway Twitty, and Brian Hoffman's Remembering Red.


text:
Why Your Travel Nurse Recruiter Always Wants to Talk On the Phone
Upping Your Side Hustle Game: The Best Side Hustles for Nurses
Naples, Florida is High on The List of Places Travel Nurses Wish to Explore
Where Do Travel Nurses Get Paid the Most ?
Work Life and Balance
Navigating Excellence: Unveiling the Top Travel Nursing Agencies of 2024!
The Importance of Self-Care for Travel Nurses
Are Travel Nurse’s Pay Rates Higher in the Winter?
How to Stay in the Holiday Spirit When You Are a Travel Nurse
Thriving as a Nurse with ADHD
© 2003 – 2024 RNvip.com® – Travel Nurse Companies. All Rights Reserved.

domain: geography


First Deputy Speaker of Parliament, Joseph Osei Owusu says, government may never be able to rely on the Speaker of Parliament, Kingsford Alban Sumana Bagbin for a successful government business.
According to him, the Majority Group will have no choice but to take advantage of the support from the independent candidate, knowing that the Speaker can not be relied upon.
Speaking at a capacity-building workshop for members of the Majority in Parliament and Ministers of State at the Rock City Hotel in Kwahu Nkwatia, the First Deputy Speaker charged members of the Majority to focus on how to get government business through in the 8th Parliament.
“We must work with the view that there are 137 of us plus one who may be presiding. In that circumstances, how do we go about taking that one advantage we have as a caucus?” the NPP legislator for Bekwai Constituency quizzed.
He said, although the Majority is the party in government, it appears the Speaker conspicuously gets missing anytime the House needs to take a critical decision.
Joseph Osei Owusu said the Majority Group will either need the Speaker in the Chair during decision times or all members of the group must vote at such sitting.
Deputy Majority Leader, Alexander Kwamina Afenyo-Markin on his part hinted that government needs innovative ways to generate and increase domestic revenue to meet the high expectations of Ghanaians.
He said, government requires support from all Ghanaians in its quest to innovatively generate revenue.
He, therefore, called on the Executive to address the growing concerns of wastage in the public finance system and enhance financial accountability in order to win the confidence of the Ghanaian people and taxpayers.
‘It is true that despite the funding challenge faced, the NPP government has still been able to work hard to reform the structure of the Ghanaian economy”, Afenyo stated.


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Senior treated for smoke inhalation
An elderly man was taken to hospital yesterday after an apartment fire in Hamilton.
A spokesman for Bermuda Fire and Rescue Service said firefighters were called out to a blaze in a one-bedroom apartment on the city’s Dundonald Street yesterday morning.
He said: “Upon arrival, smoke was coming out of the kitchen door of the apartment.
“Firefighters entered the residence wearing breathing apparatus and quickly extinguished the blaze.”
The spokesman said the fire was confined to the kitchen, but that the entire apartment had been damaged by smoke.
The occupant, who has not been named, was treated at the King Edward VII Memorial Hospital for the effects of smoke.
The fire broke out at about 10.45am.
A call about a second fire on Paget’s Harbour Road came in as firefighters tackled the Dundonald Street blaze. The spokesman said: “Firefighters noticed smoke coming from beneath the front door of an apartment.
“The fire was confined to the living room area, but the apartment received smoke damage throughout.”
No injuries were reported. A total of 11 firefighters in two trucks attended both fires. An investigation in the cause of both fires has been launched.
DeShields admits manslaughter charge
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