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Former Ulster and Ireland rugby captain Rory Best has trialled technology designed to combat agriculture export challenges after Brexit.
Ireland’s third most-capped player retired last year after three autumn games with the Barbarians, having made his 124th and final Irish appearance in the quarter-final of the Rugby World Cup in Japan.
The trial involves the continuous record of an animal from birth through to slaughter, and includes smart technology.
It is due to be rolled out to 200 farms in Northern Ireland as exporters grapple with change due to the EU withdrawal.
The company behind the venture said: “Former Ulster and Ireland rugby captain Rory Best agreed to bring the trial onto the pedigree Aberdeen Angus farm that he and his father run, continuing on the grazing field the data-driven attention to detail that he brought to the sports field.”
A new platform named NSF Verify to ensure the authenticity and integrity of agri-food supply chains is being tested.
Stephen Cox, NSF programme director, said: “Northern Ireland farmers and processors have built their industry by establishing a global reputation for the highest quality agricultural product.
“The NSF Verify platform has been designed to help lock-in that value, and in parallel, provide many of the answers to questions arising from the post-Brexit borders and relationships.”
The future of agriculture movements is among issues being addressed in the talks between London and Brussels aimed at reaching a trade deal before the transition period concludes at the end of this year.
New checking facilities for goods arriving in Northern Ireland from Britain will not be ready for the end of the Brexit transition period, a senior official has confirmed.
Contingency arrangements are being prepared, including the repurposing of old buildings and an interim paper-based checking system, when the requirement for additional regulatory checks at ports comes into effect on January 1.
Denis McMahon, the permanent British secretary in the Department of Agriculture Environment and Rural Affairs, said he and his colleagues had been left in an “impossible position” as they worked on a project that was openly opposed by their minister, Edwin Poots.
Mr McMahon said his department was legally obliged to introduce the new SPS (sanitary and phytosanitary) checking facilities and would be acting unlawfully if they did not proceed with the work.
The official said while Mr Poots maintained his opposition to the project, the DUP minister had acknowledged the legal requirement, both in domestic and international law, to set up the infrastructure.
A committee of assembly members recently heard that procurement, planning and IT issues had delayed work on the new port facilities.


Lau Siu-Fung | Radio Free Asia
Thousands of People’s Liberation Army (PLA) veterans who converged on the eastern province of Jiangsu in protest at their treatment by the ruling Chinese Communist Party have been detained and escorted home after riot police moved in to clear the demonstration site in Zhenjiang city.
“It’s all the government’s people there now; there are no veterans at the scene anymore,” a veteran who was detained shortly after arriving in Zhenjiang told RFA on Tuesday.
“The government has suppressed us by force: the veterans have no other way to survive; we have to submit to the use of force,” he said. “I was injured; I couldn’t avoid being beaten up in the end.”
A Zhenjiang resident surnamed Chen said most of the veterans had now left the city.
“They really have all gone, but I don’t know why they’ve all left,” Chen said.
Activist Dong Kuihong, who has previously helped PLA veterans lodge petitions and complaints about unpaid pensions and local governments’ failure to deliver on promised demobilization benefits, said the authorities aren’t allowing anyone to linger in Nanmen Square, the site of protests by thousands of veterans from across China in recent days.
“Over in Zhenjiang, by the government offices, there are police there, and they are refusing to allow people to stay in the area too long,” Dong told RFA. “They are preventing people from taking photos.”
“Over at the hospital, the No. 1 People’s Hospital where the veterans were taken, they are no longer to be seen,” she said. “I heard that the injured veterans are being held behind a police cordon and that even their relatives aren’t allowed to visit them and they are being guarded by Zhenjiang police.”
Dong said she had visited the hospital on Sunday but was prevented from seeing any injured veterans.
“When I got to Zhenjiang, the police took us away after they had checked our ID, and confiscated our cell phones,” she said. “There was a total lockdown, and we weren’t allowed to contact anybody.”
“They treated all of the veterans, family members and rights activists who came to Zhenjiang in the same way,” Dong said.
Several veterans who attended the protests answered the phone when contacted by RFA on Tuesday, but declined to comment, saying it was “inconvenient,” an expression often used to indicate the presence of surveillance or police officers nearby.
One veteran surnamed Su said: “Please understand that you shouldn’t call this phone because it is very risky. I’m sorry, but if I say any more, I’ll be in danger.”
An employee who answered the phone at the Zhenjiang municipal government offices declined to comment.
“Please could you call the propaganda department, because they are able to reply in a coordinated manner,” the employee said.
However, repeated calls to the Zhenjiang municipal party committee propaganda office rang unanswered during office hours on Tuesday.
The municipal and provincial authorities last week drafted in huge numbers of police and volunteers to serve as security guards after thousands of veterans gathered in protest on the city’s Nanmen Square outside the municipal government offices last week.
Video footage of the city posted to social media showed veterans gathered around regional banners in military-style rows, police in riot gear lining the streets, with large numbers of police vehicles parked and very few pedestrians.
Over the weekend, riot police moved in on the protesters in the middle of the night, beating and detaining them en masse, sources close to the protests told RFA.
Some veterans are calling on the authorities to abide by promises made to them before they signed up to fight in China’s short border war with Vietnam in 1979, while others are citing official document No. 75 issued by China’s cabinet, the State Council, in 1978 promising to find jobs for demobilized military personnel.
Clause 3 of the Military Pensions Priority Regulations requires governments to ensure that the standard of living and social situation of demobilized PLA soldiers doesn’t fall below the national average.


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The 2022 Saskatoon Fringe Festival is a chance to see cutting edge theatre and ignore what you think is a sure-fire bet for entertainment. Throw aside your cares and take in 10 days of “fly by the seat of your pants” theatre. There are choices for all ages and I can’t possibly cover it all so I’ve made a few picks to get you started. Happy Fringing!!!
There are 18 live shows to choose from happening at the Cosmopolitan Seniors’ Centre, The Refinery & The Broadway Theatre. Tickets are $16
The Kids Fringe is back with 3 live performances.
There are nine digital performance to watch from the comfort of your own home. Tickets run $10 – $20.
The festival site is a full city block square with Dufferin Ave. and 11th St framing the fun in W.E. Graham Park (behind Victoria School)
Access to the outdoor festival site and activities is completely free.
There are three outdoor stages that will delight with buskers, musical performances and community activities. Each day, there will be a featured performer. There is plenty of fun for the kids and interactive art projects that even the adults can dig into.
The full schedule, ticket info and answers to all your questions can be found at this link.
NOW ON TO THE PLAYS… (there are sooo many, these are just a few suggestions)
A Solo From The Pit (Sweden)
Cosmo Seniors Centre 13+
Follow Elias Faingersh’s personal journey as he leaves the coveted trombone chair with the Metropolitan Opera to pursue a life in comedy. Along the way, he’ll tell tales from backstage, experiment with his instrument and take a leap of faith. This show is rated for 13+.
Daddy’s Boy (South Africa)
The Refinery 13+
Master storyteller Erik de Waal is a Fringe Festival favourite and this year he returns with a story close to his heart. Daddy’s Boy dips back and forth between childhood and present day as de Waal’s father is diagnosed with Parkinson’s disease. The two have a complicated relationship, will they find some peace?
An Unaccompanied Minor’s Guide to Live (United Kingdom)
Digital Performance 13+
The production was created in England but there are some very special ties to Saskatoon. This story of expectations of adulthood and debunking along the way was created, in part, by Savana Gallant. Gallant and her two classmates Monet Comeau and Kassie Kardos were all finishing their MFA’s in Musical Theatre at Guildford School of Acting. They decided to put their skills to work to create this musical.
Half Breed Vaudeville (Saskatoon)
Cosmopolitan Seniors’ Centre 13+
From the creative collaboration of Amanda Trapp and Ken McLeod comes a comedy/musical about identity, racism and what it means to have mixed ancestry. Half Breed Vaudeville may deal with heavy subject matter but its also a production full of light and love. It’s a one-person variety hour that will have you laughing through the tears.
Cosmopolitan Seniors’ Centre Mature Audience
From the mind of Danielle Roy comes a tale of what happens to the soul when we die. This production boasts a cast of Saskatoon’s finest as they dive deep into a story somewhere between life and death. It’s a place where we have to come to terms with decisions we’ve made and what we leave behind.
Big Balloon Show (Edmonton)
The Broadway Theatre All Ages
Like a good cartoon movie, this is a show that has just as many jokes for the adults as it does for the kids. Spandy Andy and his partner-in-crime Demmi Dupri will have everyone up out of their seat and playing along. This is an interactive party filled with catchy tunes, giant balloons and tricks you didn’t think were possible.
Stick or Wizard (United Kingdom)
The Broadway Theatre All Ages
Another Fringe Favourite makes his way back to Saskatoon for this year’s festival. Oli Weatherly is a reformed teacher and current clown who will have your kids on the edge of their seats with a show that has been called “A Hilarious Waste of Time”. This tale follows Weatherly as he searches for two friends; one is a wizard; the other dreams of being a stick. This production has earned many awards on the Fringe circuit and now you can see it to.

domain: artistic


The SRAM RED AXS Crank Arm Assembly features hollow carbon Exogram crank arms for a lightweight, strong, and elegant crank. It can be paired with any SRAM AXS spider or integrated chainring, with or without power. - The 8-bolt interface is compatible with power and non-power AXS spiders and integrated chainrings - Not compatible with SRAM's 3-bolt direct mount interface - Hollow Exogram carbon arms - Spider and chainrings sold separately - DUB spindle interface - Compatible with all SRAM Road DUB bottom brackets - Number of Chainrings: No Rings, No Spider Included - Crank Intended Use: Road, Tri, Cyclocross - Pedal Spindle: 9/16" - Spindle Interface Type: SRAM DUB - Chainring BCD: Direct Mount SRAM - BB Included: No
- Optimum Power Transfer - Best Balance For Lighter Weight (-7G) And Efficiency - New Designed Crank Arm - Maintains High Rigidity And Reduces Weight - Hollowglide - 4-Arm Construction Crankset - Adapted For Race Specific Disc Brake System - Shorter Length Of Rear Center With O.L.D. 135mm - Redesign The Gear Teeth Profile To Fit Wider Gear Pitch - 50-34T/53-39T/54-42T/55-42T/52-36T - Iconic Design - Chain Line: 43.5
The Tourney TY501 crankset provides crisp, reliable shifting for your triple chainring drivetrain. - Precision indexed shifting - 8/7/6-speed compatible - 3 crank length specification available - Precise chain line control - Light and reliable shifting - Versatile performance - Wide compatibility with multiple components - Quick and precise assembly
$438.00 - $469.00
True competitors are always looking for a performance advantage—a relentless pursuit of equipment that is lighter, stiffer and stronger. To create the best drivetrain possible, SRAM started with a completely reengineered crankset design. SRAM's XX1 Eagle crankset is the lightest, stiffest and strongest on the market. A special hollow internal architecture, combined with SRAM's proprietary CARBON TUNED lay-up, allows us to build a lightweight and ultra-energy-efficient crankset perfectly suited for the high-wattage output and smooth style of cross country riding and racing. Teamed up with their Eagle direct mount chainring, and as an integral part of the Eagle drivetrain, the XX1 Eagle crankset puts more focused power into every ride.
- Octalink bolts include steel washers, JIS includes black plastic caps - HT2 mount bolts (low torque plastic, except XTR-M970 aluminum) are for mounting non-drive arm - Hollow bolts (SH-21504) not recommended for non-treated spindles
The FSA Gradient crankset is designed for enduro riding, for riders that like to crank up the trail and tear it apart on the way back down. Gradient raises the standard on strength, while keeping components lightweight. - The convertible spider design allows for different chainring and chainline configurations - Direct mount steel chainring features a thick-thin tooth design for maximum chain engagement - Crank arms are solid forged from AL7050 aluminum - Optimized for 11-speed systems - For Boost spacing - Number of Chainrings: Single - Chainline/Hub Compatibility: 150/157 Hubs, 157 Super Boost Hubs - Crank Length: 170mm - Crank Intended Use: Mountain - Pedal Spindle: 9/16" - Rings: 32 - Spindle Interface Type: 392 EVO - Drivetrain Speeds: 11 - Chainring BCD: Direct Mount FSA - BB Included: No
Turbino cranks are forged and machined from 6066 aluminum with Ciari and Turbino logos inlayed on the crankarms. - Includes external sealed 24mm euro bottom bracket - 5 bolt 110mm spider - Bore: 24 - Spindle Material: Steel - Crank Arm Material: Aluminum - Crankset Style: 2-Piece - BB Style: Euro - Chainring BCD: 110 - BB Included: Yes
$297.99 - $309.99
Big air, pure speed and total concentration: the DH world in a nutshell. It's a world where line choices are made in the blink of an eye, absolute faith in your gear is a must, and Shimano's Saint Crankset is ready to answer the call every time. Ultra-wide bottom bracket bearing spacing and hollow-forged crank arms are used for maximum rigidity and strength under demanding conditions, and a steel pedal insert adds even more burl. A single chainring keeps things simple and durable up front so you can focus on the ride, and not a dropped chain. See you at the bottom.
$164.00 - $183.00
SRAM's Rival 22 performs on par with more expensive cranksets, but at a bargain value. The crankarms are hollow and forged from 6066 aluminum for maximum strength with minimum weight. Because lightness is nothing without toughness, the Rival crankset proudly boasts SRAM's X Glide R chainrings that are specifically designed for use with the Yaw front derailleur. Durability and reliable shifting are your allies with Rival 22.
Campagnolo is all about drivetrain evolution, and their Chorus Crankset proves it. The full-carbon cranks and 4-arm spider feature a unified bolt pattern that allows for all three chainring standards. This design incorporates an 8-bolt pattern with a spider arm that not only holds the chainring in place by way of the bolt, but also supports the chainring to increase system rigidity. The crank arms and spider are hollow for maximum stiffness and minimal weight. The integrated Ultra-Torque spindle joins the crankset together via a toothed Hirth joint in the center. - Chainring BCD: Campagnolo 146 Asymmetric, Campagnolo 112 Asymmetric
With the SXg, MRP delivers a guide without compromise and with no equal. No longer does the desire for protection and both upper and lower retention have to come at the expense of weight, efficiency, or the addition of moving parts - have your cake and eat it too. With the SXg covering all those bases, it’s the first guide in history that’s equally at home on anything from aggressive, short-travel bikes to Armageddon-ready Rampage rigs, and everywhere in-between. It’s a guide that refuses to be pigeon-holed, blurring the lines between typical industry definitions - a little country and a little rock, as they say. But, in this case, it’s a whole lotta rock. High-security chain retention and bulletproof chainring defense in an innovative, lightweight package with zero efficiency loss make the SXg ideal for a wide range of uses. Whippersnapper™ technology provides lower retention without moving parts or friction. The most advanced chainguide on the market, the SXg is the go-to of the top Rampage stuntmen, World Cup downhill pilots, and superhuman enduro tacticians. - Whippersnapper™ lower guide. - Full-size, nylon HD upper guide with co-molding. - Integrated SX skid provides safeguard to the chainring and glides over rocks and obstacles. - Nylon and TPU co-molding in the Whippersnapper™ provides durable protection from external blows and mutes internal contact with the chain. - Swingset™ hardware. - All installation and adjustment operations are possible with just a single 4mm HEX wrench. - Available in 30-34t and 34-38t sizing. - Alloy guides compatible with chainlines 49mm and wider, carbon 50mm and wider. Boost 148 compatible. - ISCG-05 only. - 149g (34-38t Alloy ISCG-05)
Designed to work seamlessly with the new wave of 2×10 drivetrains, the 2x utilizes MRP's patented integrated skid chainring protection (US Patents RE 42,436 / 8,235,849 Patents Pending) and features a dual pulley tensioning system. Notable on the 2x system is the absence of a crank-mounted bash guard or guide ring, instead it relies on the front derailleur and cutting-edge lower pulley assembly for complete chain retention. The integrated skid protects the chainrings from impacts without the added weight of a full bash ring. The dual pulley tensioning system ensures that the chain is properly tensioned and in the right position, keeping it on the chainring in the roughest conditions. The dual pulleys also reduce drag and noise compared to other designs, ensuring a better riding experience. Finally, the raised top fin profile prevents the chain from dropping to the BB shell. - Removable integrated skid protects chainrings and glides over rocks and obstacles - Dual pulley design provides precise chain engagement while reducing noise and drag - Raised top fin profile prevents the chain from dropping to the BB shell - BB mounted guides are only compatible with traditional, threaded BB systems
$267.00 - $303.00
Forget front derailleurs; SRAM's Force 1 Crankset brings a game-changing upgrade in performance and reliability to cyclocross, road, and other 700c disciplines. Force 1 combines the durability, simplicity and efficiency that SRAM is known for with their 1x mountain technology. - Single-ring drivetrain simplifies functionality - SRAM X-Sync: wide-tooth, narrow-tooth chainring technology provides maximum chain control - Chainrings available in 42, 50 (110 BCD), and 52 (130BCD) teeth to conquer every course from sand dunes to gravel-road assaults - Unidirectional carbon crank arm matched to a forged aluminum spider for lightweight and durability - Weight 679g-24mm, 172.5mm, 50T, no BB - Bottom bracket not included
$164.00 - $183.00
Forget front derailleurs; SRAM's Rival 1 Crankset brings a game-changing upgrade in performance and reliability to cyclocross, road, and other 700c disciplines. It combines the durability, simplicity, and efficiency SRAM is know for on the road with their 1x mountain technology, X-Sync. - Single-ring drivetrain simplifies functionality - Forged aluminum with detachable spider: 42T and 52T X-Sync tall, square tooth design provides maximum control - Sharp, narrow tooth profile and rounded chamfer edges help manage a deflected chain - Mud-clearing recesses for the inner chain links and rollers - Weight: 799g (24mm spindle, 172.5mm, 42T, no BB)
Ride anywhere 11-speed rider tuned gearing. The power to choose how and where you ride. Consistent shifting performance and enhanced chain management. Optimal balance of durability and lightweight. High efficient and precise shifting. These cranks are Boost compatible. - Enhanced chain retention. - Better sealing and better rotation. - Model Number : FC-M8000-2 - Series : DEORE XT - Cassette Compatibility : 11 - 4-Arm Chainrings : x - Chainring Sizes : 38-28T, 36-26T, 34-24T - Bolt Circle Diameter : P.C.D. 96/64mm - Crank Arm Length : 170mm/175mm - Chain Line : 51.8mm - BB Shell Width : 68, 73mm
The North Shore Billet 2×10 Spider replaces the stock chainring spider so that you can run smaller chainrings on SRAM XX1, X01, X1, X0, X9, X7, and GX cranks using GXP bottom brackets. With the NSB 2×10 Spider you can run a more traditional 22/32T or 24/34T combination. The NSB 2×10 Spider is designed to use any standard 64 / 104 BCD 9 speed chainring. The distance between the rings and the distance from the centre of the bottom bracket is the same as the 120 BCD spider so the set up is simple and the shifting is quick!
Promax SQ-1 Crank Arm sets more than cover your need for hard-to-find lengths and hard-to-miss colors. - BCD: 110mm - Weight: 25.2 oz.
Back in the day, we drilled holes in our chainrings to make them lighter. The weight savings were minimal, but they sure looked cool. Velo Orange's Drillium Crankset recaptures the look. It's based on their Grand Cru 110 cranks with a very low 150mm Q-factor. And, while it may look like a vintage crank, the Drillium is cold forged in modern high-strength alloy. The 7075 alloy chainrings are highly durable, featuring ramps and pins for fast and smooth shifting with 6-10 speed drivetrains. The crank arms have classically styled reliefs, and the alloy dust caps function as self extractors with the supplied crank bolts. - Spindle interface: square taper JIS - BCD: 110mm - Weight: 645g
Wolf Tooth's CAMO stands for Chainline and Material Optimization. Available in various chainlines and spider configurations, CAMO spiders allow the use of previously unavailable chainring styles, materials, and chainlines in a lightweight, modular, and customizable package. These spiders are for use with the RaceFace cranksets that have removable Cinch spiders/chainrings and are only compatible with CAMO rings and bolts. Three different chainline options are available. The number and letter refer to the mm offset and direction from the mounting face to the centerline of the teeth: - M8 (minus 8mm - dished toward the frame): For 49mm chainline, used with GXP and long-spindle BB30 cranks. Designed for bikes with 135mm QR, 142mm thru axle, and some 148mm bikes. - M5 (minus 5mm - dished toward the frame): For 52mm chainline (Boost) - P2 (plus 2mm - dished outward away from the frame): For fat bikes that have 190/197 rear spacing but use a 100mm-spindle crank
- Replacement right-side crank arm for Shimano STEPS City E6000.
Wolf Tooth's CAMO stands for Chainline and Material Optimization. Available in various chainlines and spider configurations, CAMO spiders allow the use of previously unavailable chainring styles, materials, and chainlines in a lightweight, modular, and customizable package. These spiders are for use with the SRAM cranksets that have removable Direct Mount spiders and are only compatible with CAMO rings and bolts. Four different chainline options are available. The number and letter refer to the mm offset and direction from the mounting face to the centerline of the teeth: - M8 (minus 8mm - dished toward the frame): For 49mm chainline, used with GXP and long-spindle BB30 cranks. Designed for bikes with 135mm QR, 142mm thru axle, and some 148mm bikes. - M5 (minus 5mm - dished toward the frame): For 52mm chainline (Boost) - M2 (minus 2mm - dished toward the frame): For 49mm chainline on short-spindle BB30 cranks - P2 (plus 2mm - dished outward away from the frame): For fat bikes that have 190/197 rear spacing but use a 100mm-spindle crank. Can also be used to achieve a Boost chainline with a short-spindle BB30 crank.
FSA’s Road PowerBox Alloy Crankset employs a P2M convertible spider design for multiple chainring options. FSA's alloy arms and BB386EVO spindle mated together produce a very lightweight, extremely versatile power meter crankset available with a double chaining configuration. Firmware upgrades available for more features. - Cold forged AL6061/T6 aluminum crank arms - BB386EVO 30mm AL 7050 alloy spindle fits every frame (purchase BB separately) - AL7075 CNC chainrings - Chromoly chainring bolts - Fits Shimano and SRAM 10-11 speed systems - Spider-based power sensors provide total power output measurement of both legs, with Left & Right leg output analysis available with system upgrade - Bluetooth connectivity available with system upgrade - Battery life is approximately 300-400 hours - Easy-to-replace CR2450 battery
The Wheels Manufacturing 386 EVO Adapter for 22/24mm Spindle Cranks adapts SRAM/Truvativ cranks to 386EVO-standard frames. Simply tap the adapters into the 6806 bearing in the BB shell or cups, then install the cranks using the included spacers to adjust chainline or to take up any side-to-side movement in the crank. - Machined engineering-grade Delrin - 48g/pr Includes - (1) - 24mm ID adapter (for right-side) - (1) - 22mm ID adapter (for left-side) - (8) - 0.7mm spacers
The Easton Spider and Ring assembly features the Cinch Direct Mount System, making a swap between ring configurations a fast and simple procedure. This system also provides a significant weight savings by eliminating the material overlap and extra bolt hardware that is required for a traditional spider with chainring configuration. - EA90 Aluminum
The new Super Record 12x2 Speed crankset: an intense concentration of innovation that results in the greatest possible stiffness and precision in derailing, whilst providing a dedicated aerodynamic “super design." The new carbon fiber Super Record 12x2 Speed crankset has been made lighter on the inside through Campagnolo Hollow Technology, which uses the Ultra-Torque bracket system with a titanium axle to transfer all of the force the athlete applies to the pedal to the drivetrain. The new Super Record 12x2 Speed crankset can be installed on any type of frame, whether or not it is being used with disc brakes because it optimizes the chain line on the frame with a rear hub flange measuring 130, 135 or 142 millimeters, without affecting the Q factor, which remains constant at 145.5 millimeters thanks to the new hand crank design. The use of ceramic Cult bearings leads to obtaining the smooth ride that the Campagnolo brand is known for. The innovative design of the outer chainring ensures faster, quieter derailing owing to the contoured pin. The symmetrical design of the inner chainring teeth allows improved stability with chain crossovers. The double wheel sizing standards (112 and 145 millimeters) combined with the eight fixing screws, optimize weight and stiffness through the increased use of carbon fiber. The varying number of pins for each of the three chainring combinations (34/50, 36/52, 39/53) facilitates upshifting due to the optimized free strokes associated with each combination. The special drains on the inside of the outer chainrings optimize performance when downshifting in dead spots.
SRAM pioneered the 1x drivetrain, and the SRAM Force 1 crankset evolves the innovation. It’s lighter, stronger, and simpler—non-aero chainrings can now be installed with a single tool. For cross, TT, tri and crits, this is the king of 1x. - Single-ring drivetrain simplifies functionality and reduces weight - Non-aero chainrings can be installed with a single tool, making gearing changes a breeze - SRAM X-SYNC wide-tooth, narrow-tooth chainring technology provides maximum chain control - Can be upgraded to a power meter
$4.50 - $6.25
Used to adjust crank chainline or ensure proper bearing preload when using 30mm spindle cranks. - Inner Diameter: 30mm - Outer Diameter: 41.5mm - Machined engineering-grade Delrin - Sold Individually
The RS510 crankset features a 4-arm design that's light and stiff, providing high performance on a low budget. - For 11-speed drivetrains - Compatible with frames of O.L.D. 135 mm and 410 mm chainstay length - Affordable and high-end style crankset
Shimano XTR M9100 cranks feature a lightweight and rigid design thanks to Hollowtech II crank construction. Chainrings can be easily exchanged with the direct mount system and one key release. - Double front chainring set up - Special gear teeth profile designed for MTB riding usage - Crankset can be used as a common component - Smoother driving even over bumpy terrain - Lighter and stiffer design - Direct mount system enables easy chainring swaps - Q-factor: 168 mm - Chainline: 52 mm - Bottom bracket compatibility: Hollowtech II - 12-speed
Shimano's new FC-RX600-11 crank balances weight and efficiency for mixed-terrain riding. Gearing options cater to the specific demands of gravel riding, with tighter gear steps for maintaining optimum pedaling cadence. The 2x11-speed crank is available in a 46-30T or 40T chainring combination and 170, 172.5, and 175mm crank arm lengths. - Wider gear range for long tours or unknown terrain - Optimum gearing for mixed terrains and riding styles - Gear combination: 46-30T, 40T
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5 Amazing Things About Rachel McAdams
Versatile actress with a wide range of roles.
Began her career in theater in Canada.
Environmental activist and supporter of various causes.
Fluent in French and acted in French-language films.
Award-winning actress with nominations for an Oscar, Golden Globe, and SAG Award.
Click Here See Pics

domain: celebrity


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Lovers of everything Mediterranean will soon be capable of getting their quick fix at a new restaurant in the up and coming Marketplace at Tech Center development. Officials with Zoes Kitchen Menu Prices announced Thursday that its newest eatery will open Sept. 17 at 12090 Jefferson Ave, Suite 1240 in Newport News. The restaurant is scheduled to start from 11 a.m. to 9 p.m. daily, and wants to offer beer and wine, a news release said.
“Our company is thrilled to be a part of the Newport News community and expand our presence in Virginia,” said Regional Operator of Zoës Kitchen, Tony Fratoe, in a news release. The new restaurant marks the eatery’s 14th in Virginia and its 160th in the nation, the news release said. To celebrate its opening at Tech Center, Zoës Kitchen is handing out 500 entrées at its Newport News location, this news release said. Additionally there is a opportunity to win a grand prize of free Zoës for a year in the new restaurant.
Zoës Kitchen is really a fast casual restaurant chain headquartered in Plano, Texas, United States Of America. Serving a menu of selection of chicken salad, pasta salad, pitas and grilled chicken sandwiches, the chain has grown to incorporate 203 locations across 17 states with wants to expand further. Zoës’ menu features Mediterranean-inspired comfort food with made-from-scratch recipes using fresh ingredients. Kevin Miles (CEO), who joined Zoës during 2009, succeeded Greg Dollarhyde as president in March 2011.
Zoës Kitchen was originally incorporated in Jefferson County, Alabama, in June 1995 as Zoe’s Kitchen, Inc. It absolutely was founded by Zoë and Marcus Cassimus. Originally, the restaurants were not franchised, with Cassimus retaining a 51 percent ownership stake in most newly opened locations.
Its first location opened in October 1995 in downtown Homewood. A second location opened within the Riverchase portion of Hoover in 1999 and a third in downtown Birmingham in March 2001. The restaurant continued its expansion with all the opening of its first store outside of the Birmingham area in Tuscaloosa in May 2001 and its first out-of-state location in Nashville, Tennessee, in the fall of 2001. By 2006, Zoës had expanded to sixteen restaurants, with eight situated in Alabama yet others based in Phoenix, Nashville, Memphis, Baton Rouge and Destin.
With 20 stores open by 2007, Cassimus sold a majority ownership stake to Brentwood Associates of La. After the purchase, What Time Does Zoes Kitchen Open announced which he would remain as chief executive, the company would remain headquartered in Birmingham, and also the menu would not be affected. Additionally it absolutely was stated that the sale could potentially result in the opening of 200 new fbxxji within the next 5 years. By Spring 2008 GE Capital Solutions loaned the company $ten million to enable for the creation of 50 new stores over the southeast and southwest.
In November 2008, Cassimus resigned, with Greg Dollarhyde taking his place as CEO. Formerly the CEO of Baja Fresh, Dollarhyde announced he will be seeking to expand the restaurant to new locales with two-thirds remaining company owned as well as the remainder being franchised.

domain: food


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Release Day Round-Up is an ongoing feature here at Bigfanboy that will be posted on the day prior to any big release to showcase the important information and marketing material for the new movies being released the following day. This way you can make an informed decision on what movie (or movies) you will see on opening weekend. As always, let us know what you think in the comments, if you would like anything added and if you plan on seeing the particular movie being highlighted on opening weekend, sometime down the road, wait for it on home release or passing all together. Here’s all you could want to know about ICE AGE: CONTINENTAL DRIFT:
Critic Consensus: Rotten Tomatoes
MPAA: PG for mild rude humor and action/peril.
Presentation: 2D, 3D, IMAX 3D
Studio: 20th Century Fox
Genre: Animation, Adventure, Comedy, Family
Screenwriters: Michael Berg and Jason Fuchs
Directed By: Steve Martino and Michael Thurmeier
Starring: Ray Romano, Queen Latifah, Denis Leary, John Leguizamo, Seann William Scott, Josh Peck, Peter Dinklage, Wanda Sykes, Aziz Ansari, Keke Palmer, Drake, Jennifer Lopez, Heather Morris, Joy Behar, Nicki Minaj, Josh Gad, Alan Tudyk, Nick Frost, Kunal Nayyar, Alain Chabat and JB Smoove.
Synopsis: In “Ice Age: Continental Drift,” Scrat’s nutty pursuit of the cursed acorn, which he’s been after since the dawn of time, has world-changing consequences — a continental cataclysm that triggers the greatest adventure of all for Manny, Diego and Sid. In the wake of these earth-shattering upheavals, Sid reunites with his long lost family, and the gang encounters a ragtag menagerie of colorful new characters determined to stop them from returning home.
Theatrical Trailer 2:
The Dark Nut:

domain: entertainment


Opening an account with HTC is simple and hassle-free. Reap the benefits when it comes to tool hire.
Armorgard LoadAll LA1000
Product Code: LA1000
£1,027.00 (+ VAT)
The LoadAll mobile trolly can save space on site, in a delivery truck or in the yard. Designed for storing and transporting large sheet materials e.g. plasterboard and can be easily folded and stacked when not in use.


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Eucrisa® is a topical treatment for eczema that works on your skin’s surface and underneath it, calming overactive enzymes that cause inflammation.
Prescription medication requires an online medical consultation. If appropriate, a licensed physician will prescribe a prescription treatment as part of your personalized treatment plan.
HOW IT WORKS
Eucrisa® helps calm down swelling, itching, and redness caused by eczema by regulating overactive enzymes that cause inflammation. It typically takes about 1 month of using Eucrisa® to see and feel improvements, though some patients feel relief after just 1 week.
Eucrisa® penetrates skin cells to block a specific inflammation-causing enzyme called PDE4 and may be used over longer periods of time because it’s steroid-free.
Eucrisa® is often prescribed for mild to moderate symptoms that affect more sensitive skin and haven’t responded to other treatments. Our medical providers will learn about your unique eczema symptoms and treatment history to design a care plan that’s right for your skin.
How Facet Works
Yes, you really can do everything online.
1. Complete your online medical assessment Answer questions about your medical history and submit photos for our medical team to review via our secure, HIPAA-compliant platform.
2. Get your recommended treatment plan Your medical provider will select the right clinically proven medications for your skin. We will deliver them straight to your door.
3. Find lasting skin relief Easily check-in with your dedicated medical provider to track your skin’s progress and adjust your treatment plan. Most patients have 1 check-in every 3 months.

domain: health


With 15 years in business ASG has extensive experience serving many markets. Our manufacturing process allows us to accurately build exactly to your design and if needed, we can assist in the design process, ASG build according to the applicable standards, specific to your industry.
ASG provides a broad range of products for data transfer, control and monitoring, for mobile power distribution systems like the PW PowerSystems MobilePac®. ASG provides pre-engineered and customized (build-to-print) Connectorized cables that are used in the control system, operation panel, protective relays, batteries and charger, motor control center, and the hydraulic start package.
ASG has extensive experience in the oil – gas industry, providing connectorized cables designed for the machines and instruments used across multiple harsh environments including: Oilfield drilling derricks, Well sites, Production platforms, Offshore drilling platforms, Pump rooms, and Telemetry systems just to name a few.
At ASG we can develop industrial cable assemblies for most equipment, including automated tools that rely on DeviceNet or Ethernet. We can provide custom braided cable to improve abrasion resistance and tensile strength, and can incorporate custom colors to make installation and maintenance easier. Almost every type of connector, including M8 / M12, LEMO and Fischer connectors, as well as waterproof and hermetically sealed connectors, are available.
ASG supplies a wide range of interconnect products for use in military applications, including MIL-SPEC connectors and connector accessories, MIL-SPEC contacts, filter connectors, cable assemblies, wire harnesses, and power cables.
Marine vessels come into port for a variety of reasons, whether it is to load or unload cargo, crew, etc..During extended time in port, ships may opt to connect to the local grid or a local generation source to maintain shipboard power. This temporary connection is referred to as Alternate Marine Power (AMP) or Cold Ironing (a Navy term).
ASG is an ISO 9001:2008 certified and experienced manufacturer of cable interconnect products for passenger rail, commuter high-speed rail, commuter light/heavy rail transit, locomotive builders, freight, private rail, and new car/refurbishment builders and has been building cables for the rail industry for over a decade.


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Challenge your athletic, racing, and aiming abilities with Log Ride, Fiesta Village, and Boardwalk games! If you win, you receive a prize! Are you game enough?» View More
Print & GoSave Time and Money! Buy and print your tickets at home. Buy Now
Games and ArcadesIs your game face on? Challenge your family and friends at different interactive games located in Fiesta, Boardwalk and Log Ride areas. There are also sports games featuring baseball, basketball, and soccer. Not a sports fan? No Problem! Boardwalk, Fiesta Village, and Ghost Town are equip with full token-taking arcades, featuring the latest and most popular games!

domain: hobby


ATLANTA – Aklima Khondoker, All Voting is Local Georgia state director, issued the following statement in response to Georgia Secretary of State Brad Raffensperger’s ploy to move thousands of registered voters to inactive status less than three months before Election Day:
“Secretary Raffensperger’s plot to move thousands of duly qualified voters to inactive status is beyond abhorrent because it adds an unnecessary layer of voter confusion less than 80 days before the general election. Rather than fix the multitude of issues that disenfranchised countless Georgians in the primary election, he’d rather see them gone.
“We applauded Secretary Raffensperger’s initial decision to send absentee requests to registered voters in the primary, but now his office is using undeliverable absentee ballot requests as the starting point to the purge process.
“In addition to sowing the seeds of confusion for our voters, Secretary Raffensperger is adding an extra burden on our already strained poll workers. If inactive voters show up to cast their ballot, poll workers will have to spend additional time checking the voters’ status, which will result in even longer lines.”
Thousands of Georgia voters were recently notified that the Secretary of State is placing them on ‘inactive’ status because absentee applications sent to them in the spring were undeliverable. Inactive status is the first step to purging voters from the rolls and canceling their registration. Secretary of State Raffensperger’s threat to move registered voters to inactive marks the second time since 2017 that this office has attempted to disenfranchise Georgians. His office’s actions wrongly purged more than 87,000 lawfully registered voters in 2017.
Voters can take themselves off of inactive status through any contact with their county election office, including voting. Voters should check their registration and update their information online at https://www.mvp.sos.ga.gov/MVP/mvp.do.


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Benefits of American Express
Credit cards are actually a great boom for some and a disaster for other people. On the other hand, credit cards are a very effective way of keeping track of all your expenses. The American Express card is one of the best ways to enter the growing world of these credit cards. There are various benefits that come with this particular credit card and some of them are listed below.
1. Great rates offered
The most important benefit that you are going to derive from the American Express credit card is basically great rates. These are the interest rates that each credit lending company charges on their credit cards. For instance, if you acquire a credit card which charges a high interest rate, then it is highly likely that you are also going to require making much higher payments every month whenever the payments are due. In addition to that, if you get a debt for the credit card, the amount paid will be considerably higher.
With the American Express credit card, you are going to receive very competitive interest rates that are specifically designed to suit your specific budget requirements.
2. Caters for small business
For those with small businesses and are clueless in terms of getting the most suitable credit card that meets their business needs, then you ought to take into consideration the American Express credit card. There are various shopping benefits, travel concessions and lucrative cash back benefits offered by this particular credit card. You will find that most American Express cards do not have any annual fees with very good introductory offers of zero percent APR.
3. No spending limit
If you are a frequent flyer, then you should consider getting an American Express card since it does not have a spending limit. At the same time, there are other special privileges and travelling benefits offered to make certain that your journey goes on smoothly.
The only disadvantage with using the American Express card is that you are exposed to fraud. It also enables impulse purchases which might seriously harm your saving goals.

domain: finance


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Glass House Plans Elegant 50 Modern Single Story House Fdl Planner
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domain: design


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Nifedipine is a drug belonging to a class of pharmacological agents known as the calcium channel blockers. Nifedipine is 3,5-pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-, dimethyl ester, C 17 H 18 N 2 O 6 , and has the structural formula:
Nifedipine is a yellow crystalline substance, practically insoluble in water but soluble in ethanol. It has a molecular weight of 346.3. PROCARDIA XL is a registered trademark for Nifedipine GITS. Nifedipine GITS (Gastrointestinal Therapeutic System) Tablet is formulated as a once-a-day controlled-release tablet for oral administration designed to deliver 30, 60, or 90 mg of nifedipine.
Inert ingredients in the formulations are: cellulose acetate; hydroxypropyl cellulose; hydroxypropyl methylcellulose; magnesium stearate; polyethylene glycol; polyethylene oxide; red ferric oxide; sodium chloride; titanium dioxide.
PROCARDIA XL Extended Release Tablet is similar in appearance to a conventional tablet. It consists, however, of a semipermeable membrane surrounding an osmotically active drug core. The core itself is divided into two layers: an "active" layer containing the drug, and a "push" layer containing pharmacologically inert (but osmotically active) components. As water from the gastrointestinal tract enters the tablet, pressure increases in the osmotic layer and "pushes" against the drug layer, releasing drug through the precision laser-drilled tablet orifice in the active layer.
PROCARDIA XL Extended Release Tablet is designed to provide nifedipine at an approximately constant rate over 24 hours. This controlled rate of drug delivery into the gastrointestinal lumen is independent of pH or gastrointestinal motility. PROCARDIA XL depends for its action on the existence of an osmotic gradient between the contents of the bi-layer core and fluid in the GI tract. Drug delivery is essentially constant as long as the osmotic gradient remains constant, and then gradually falls to zero. Upon swallowing, the biologically inert components of the tablet remain intact during GI transit and are eliminated in the feces as an insoluble shell.
Nifedipine is a calcium ion influx inhibitor (slow-channel blocker or calcium ion antagonist) and inhibits the transmembrane influx of calcium ions into cardiac muscle and smooth muscle. The contractile processes of cardiac muscle and vascular smooth muscle are dependent upon the movement of extracellular calcium ions into these cells through specific ion channels. Nifedipine selectively inhibits calcium ion influx across the cell membrane of cardiac muscle and vascular smooth muscle without altering serum calcium concentrations.
Nifedipine is completely absorbed after oral administration. Plasma drug concentrations rise at a gradual, controlled rate after a PROCARDIA XL Extended Release Tablet dose and reach a plateau at approximately six hours after the first dose. For subsequent doses, relatively constant plasma concentrations at this plateau are maintained with minimal fluctuations over the 24-hour dosing interval. About a four-fold higher fluctuation index (ratio of peak to trough plasma concentration) was observed with the conventional immediate-release Procardia® capsule at t.i.d. dosing than with once daily PROCARDIA XL Extended Release Tablet. At steady-state the bioavailability of the PROCARDIA XL Extended Release Tablet is 86% relative to Procardia capsules. Administration of the PROCARDIA XL Extended Release Tablet in the presence of food slightly alters the early rate of drug absorption, but does not influence the extent of drug bioavailability. Markedly reduced GI retention time over prolonged periods (i.e., short bowel syndrome), however, may influence the pharmacokinetic profile of the drug which could potentially result in lower plasma concentrations. of PROCARDIA XL Extended Release Tablets are linear over the dose range of 30 to 180 mg in that plasma drug concentrations are proportional to dose administered. There was no evidence of dose dumping either in the presence or absence of food for over 150 subjects in pharmacokinetic studies.
Nifedipine is extensively metabolized to highly water-soluble, inactive metabolites accounting for 60 to 80% of the dose excreted in the urine. The elimination half-life of nifedipine is approximately two hours. Only traces (less than 0.1% of the dose) of unchanged form can be detected in the urine. The remainder is excreted in the feces in metabolized form, most likely as a result of biliary excretion. Thus, the pharmacokinetics of nifedipine are not significantly influenced by the degree of renal impairment. Patients in hemodialysis or chronic ambulatory peritoneal dialysis have not reported significantly altered pharmacokinetics of nifedipine. Since hepatic biotransformation is the predominant route for the disposition of nifedipine, the pharmacokinetics may be altered in patients with chronic liver disease. Patients with hepatic impairment (liver cirrhosis) have a longer disposition half-life and higher bioavailability of nifedipine than healthy volunteers. The degree of serum protein binding of nifedipine is high (92-98%). Protein binding may be greatly reduced in patients with renal or hepatic impairment.
Like other slow-channel blockers, nifedipine exerts a negative inotropic effect on isolated myocardial tissue. This is rarely, if ever, seen in intact animals or man, probably because of reflex responses to its vasodilating effects. In man, nifedipine decreases peripheral vascular resistance which leads to a fall in systolic and diastolic pressures, usually minimal in normotensive volunteers (less than 5-10 mm Hg systolic), but sometimes larger. With PROCARDIA XL Extended Release Tablets, these decreases in blood pressure are not accompanied by any significant change in heart rate. Hemodynamic studies in patients with normal ventricular function have generally found a small increase in cardiac index without major effects on ejection fraction, left ventricular end diastolic pressure (LVEDP) or volume (LVEDV). In patients with impaired ventricular function, most acute studies have shown some increase in ejection fraction and reduction in left ventricular filling pressure.
Although, like other members of its class, nifedipine causes a slight depression of sinoatrial node function and atrioventricular conduction in isolated myocardial preparations, such effects have not been seen in studies in intact animals or in man. In formal electrophysiologic studies, predominantly in patients with normal conduction systems, nifedipine has had no tendency to prolong atrioventricular conduction or sinus node recovery time, or to slow sinus rate.
Known hypersensitivity reaction to nifedipine.
Although in most angina patients the hypotensive effect of nifedipine is modest and well tolerated, occasional patients have had excessive and poorly tolerated hypotension. These responses have usually occurred during initial titration or at the time of subsequent upward dosage adjustment, and may be more likely in patients on concomitant beta blockers.
Severe hypotension and/or increased fluid volume requirements have been reported in patients receiving nifedipine together with a beta-blocking agent who underwent coronary artery bypass surgery using high dose fentanyl anesthesia. The interaction with high dose fentanyl appears to be due to the combination of nifedipine and a beta blocker, but the possibility that it may occur with nifedipine alone, with low doses of fentanyl, in other surgical procedures, or with other narcotic analgesics cannot be ruled out. In nifedipine-treated patients where surgery using high dose fentanyl anesthesia is contemplated, the physician should be aware of these potential problems and if the patient' condition permits, sufficient time (at least 36 hours) should be allowed for nifedipine to be washed out of the body prior to surgery.
The following information should be taken into account in those patients who are being treated for hypertension as well as angina:
Rarely, patients, particularly those who have severe obstructive coronary artery disease, have developed well documented increased frequency, duration and/or severity of angina or acute myocardial infarction on starting nifedipine or at the time of dosage increase. The mechanism of this effect is not established.
It is important to taper beta blockers if possible, rather than stopping them abruptly before beginning nifedipine. Patients recently withdrawn from beta blockers may develop a withdrawal syndrome with increased angina, probably related to increased sensitivity to catecholamines. Initiation of nifedipine treatment will not prevent this occurrence and on occasion has been reported to increase it.
Rarely, patients, usually receiving a beta blocker, have developed heart failure after beginning nifedipine. Patients with tight aortic stenosis may be at greater risk for such an event, as the unloading effect of nifedipine would be expected to be of less benefit to those patients, owing to their fixed impedance to flow across the aortic valve.
General--Hypotension: Because nifedipine decreases peripheral vascular resistance, careful monitoring of blood pressure during the initial administration and titration of nifedipine is suggested. Close observation is especially recommended for patients already taking medications that are known to lower blood pressure. (See . )
Peripheral Edema: Mild to moderate peripheral edema occurs in a dose dependent manner with an incidence ranging from approximately 10% to about 30% at the highest dose studied (180 mg). It is a localized phenomenon thought to be associated with vasodilation of dependent arterioles and small blood vessels and not due to left ventricular dysfunction or generalized fluid retention. With patients whose angina or hypertension is complicated by congestive heart failure, care should be taken to differentiate this peripheral edema from the effects of increasing left ventricular dysfunction.
Other: As with any other non-deformable material, caution should be used when administering PROCARDIA XL in patients with preexisting severe gastrointestinal narrowing (pathologic or iatrogenic). There have been rare reports of obstructive symptoms in patients with known strictures in association with the ingestion of PROCARDIA XL.
Information for Patients: PROCARDIA XL Extended Release Tablets should be swallowed whole. Do not chew, divide or crush tablets. Do not be concerned if you occasionally notice in your stool something that looks like a tablet. In PROCARDIA XL, the medication is contained within a nonabsorbable shell that has been specially designed to slowly release the drug for your body to absorb. When this process is completed, the empty tablet is eliminated from your body.
Laboratory Tests: Rare, usually transient, but occasionally significant elevations of enzymes such as alkaline phosphatase, CPK, LDH, SGOT, and SGPT have been noted. The relationship to nifedipine therapy is uncertain in most cases, but probable in some. These laboratory abnormalities have rarely been associated with clinical symptoms; however, cholestasis with or without jaundice has been reported. A small (5.4%) increase in mean alkaline phosphatase was noted in patients treated with PROCARDIA XL. This was an isolated finding not associated with clinical symptoms and it rarely resulted in values which fell outside the normal range. Rare instances of allergic hepatitis have been reported. In controlled studies, PROCARDIA XL did not adversely affect serum uric acid, glucose, or cholesterol. Serum potassium was unchanged in patients receiving PROCARDIA XL in the absence of concomitant diuretic therapy, and slightly decreased in patients receiving concomitant diuretics.
Nifedipine, like other calcium channel blockers, decreases platelet aggregation in vitro . Limited clinical studies have demonstrated a moderate but statistically significant decrease in platelet aggregation and an increase in bleeding time in some nifedipine patients. This is thought to be a function of inhibition of calcium transport across the platelet membrane. No clinical significance for these findings has been demonstrated.
Positive direct Coombs test with/without hemolytic anemia has been reported but a causal relationship between nifedipine administration and positivity of this laboratory test, including hemolysis, could not be determined.
Although nifedipine has been used safely in patients with renal dysfunction and has been reported to exert a beneficial effect, in certain cases, rare, reversible elevations in BUN and serum creatinine have been reported in patients with pre-existing chronic renal insufficiency. The relationship to nifedipine therapy is uncertain in most cases but probable in some.
Drug Interactions: Beta-adrenergic blocking agents: (See and . ) Experience in over 1400 patients with Procardia capsules in a noncomparative clinical trial has shown that concomitant administration of nifedipine and beta-blocking agents is usually well tolerated, but there have been occasional literature reports suggesting that the combination may increase the likelihood of congestive heart failure, severe hypotension, or exacerbation of angina.
Long-acting Nitrates: Nifedipine may be safely co-administered with nitrates, but there have been no controlled studies to evaluate the antianginal effectiveness of this combination.
Digitalis: Administration of nifedipine with digoxin increased digoxin levels in nine of twelve normal volunteers. The average increase was 45%. Another investigator found no increase in digoxin levels in thirteen patients with coronary artery disease. In an uncontrolled study of over two hundred patients with congestive heart failure during which digoxin blood levels were not measured, digitalis toxicity was not observed. Since there have been isolated reports of patients with elevated digoxin levels, it is recommended that digoxin levels be monitored when initiating, adjusting, and discontinuing nifedipine to avoid possible over- or under-digitalization.
Coumarin Anticoagulants: There have been rare reports of increased prothrombin time in patients taking coumarin anticoagulants to whom nifedipine was administered. However, the relationship to nifedipine therapy is uncertain.
Cimetidine: A study in six healthy volunteers has shown a significant increase in peak nifedipine plasma levels (80%) and area-under-the-curve (74%), after a one week course of cimetidine at 1000 mg per day and nifedipine at 40 mg per day. Ranitidine produced smaller, non-significant increases. The effect may be mediated by the known inhibition of cimetidine on hepatic cytochrome P-450, the enzyme system probably responsible for the first-pass metabolism of nifedipine. If nifedipine therapy is initiated in a patient currently receiving cimetidine, cautious titration is advised.
Nifedipine was administered orally to rats for two years and was not shown to be carcinogenic. When given to rats prior to mating, nifedipine caused reduced fertility at a dose approximately 30 times the maximum recommended human dose. There is a literature report of reversible reduction in the ability of human sperm obtained from a limited number of infertile men taking recommended doses of nifedipine to bind to and fertilize an ovum in vitro. In vivo mutagenicity studies were negative.
Pregnancy: Pregnancy Category C: Nifedipine has been shown to produce teratogenic findings in rats and rabbits, including digital anomalies similar to those reported for phenytoin. Digital anomalies have been reported to occur with other members of the dihydropyridine class and are possibly a result of compromised uterine blood flow. Nifedipine administration was associated with a variety of embryotoxic, placentotoxic, and fetotoxic effects, including stunted fetuses (rats, mice, rabbits), rib deformities (mice), cleft palate (mice), small placentas and underdeveloped chorionic villi (monkeys), embryonic and fetal deaths (rats, mice, rabbits), and prolonged pregnancy/decreased neonatal survival (rats; not evaluated in other species). On a mg/kg basis, all of the doses associated with the teratogenic embryotoxic or fetotoxic effects in animals were higher (3.5 to 42 times) than the maximum recommended human dose of 120 mg/day. On a mg/m 2 basis, some doses were higher and some were lower than the maximum recommended human dose but all are within an order of magnitude of it. The doses associated with placentotoxic effects in monkeys were equivalent to or lower than the maximum recommended human dose on a mg/m 2 basis
There are no adequate and well-controlled studies in pregnant women. PROCARDIA XL Extended Release Tablets should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Pediatric Use: Safety and effectiveness in pediatric patients have not been established.
Over 1000 patients from both controlled and open trials with PROCARDIA XL Extended Release Tablets in hypertension and angina were included in the evaluation of adverse experiences. All side effects reported during PROCARDIA XL Extended Release Tablet therapy were tabulated independent of their causal relation to medication. The most common side effect reported with PROCARDIA XL was edema which was dose related and ranged in frequency from approximately 10% to about 30% at the highest dose studied (180 mg). Other common adverse experiences reported in placebo-controlled trials include:
Of these, only edema and headache were more common in PROCARDIA XL patients than placebo patients.
The following adverse reactions occurred with an incidence of less than 3.0%. With the exception of leg cramps, the incidence of these side effects was similar to that of placebo alone.
Body as a Whole/Systemic: asthenia, flushing, pain
Central Nervous System: insomnia, nervousness, paresthesia, somnolence
Dermatologic: pruritus, rash
Gastrointestinal: abdominal pain, diarrhea, dry mouth, dyspepsia, flatulence
Musculoskeletal: arthralgia, leg cramps
Respiratory chest pain (nonspecific), dyspnea
Urogenital: impotence, polyuria
Other adverse reactions were reported sporadically with an incidence of 1.0% or less. These include:
Body as a Whole/Systemic: face edema, fever, hot flashes, malaise, periorbital edema, rigors
Cardiovascular arrhythmia, hypotension, increased angina, tachycardia, syncope
Central Nervous System: anxiety, ataxia, decreased libido, depression, hypertonia, hypoesthesia, migraine, paroniria, tremor, vertigo
Dermatologic: alopecia, increased sweating, urticaria, purpura
Gastrointestinal: eructation, gastroesophageal reflux, gum hyperplasia, melena, vomiting, weight increase
Musculoskeletal: back pain, gout, myalgias
Respiratory coughing, epistaxis, upper respiratory tract infection, respiratory disorder, sinusitis
Special Senses: abnormal lacrimation, abnormal vision, taste perversion, tinnitus
Urogenital/Reproductive: breast pain, dysuria, hematuria, nocturia
Adverse experiences which occurred in less than 1 in 1000 patients cannot be distinguished from concurrent disease states or medications.
The following adverse experiences, reported in less than 1% of patients, occurred under conditions (e.g., open trials, marketing experience) where a causal relationship is uncertain: gastrointestinal irritation, gastrointestinal bleeding, gynecomastia.
In multiple-dose U.S. and foreign controlled studies with nifedipine capsules in which adverse reactions were reported spontaneously, adverse effects were frequent but generally not serious and rarely required discontinuation of therapy or dosage adjustment. Most were expected consequences of the vasodilator effects of nifedipine.
There is also a large uncontrolled experience in over 2100 patients in the United States. Most of the patients had vasospastic or resistant angina pectoris, and about half had concomitant treatment with beta-adrenergic blocking agents. The relatively common adverse events were similar in nature to those seen with PROCARDIA XL.
In addition, more serious adverse events were observed, not readily distinguishable from the natural history of the disease in these patients. It remains possible, however, that some or many of these events were drug related. Myocardial infarction occurred in about 4% of patients and congestive heart failure or pulmonary edema in about 2%. Ventricular arrhythmias or conduction disturbances each occurred in fewer than 0.5% of patients.
In a subgroup of over 1000 patients receiving PROCARDIA with concomitant beta blocker therapy, the pattern and incidence of adverse experiences was not different from that of the entire group of PROCARDIA (nifedipine) treated patients. (See PRECAUTIONS. )
In a subgroup of approximately 250 patients with a diagnosis of congestive heart failure as well as angina, dizziness, or lightheadedness, peripheral edema, headache or flushing each occurred in one in eight patients. Hypotension occurred in about one in 20 patients. Syncope occurred in approximately one patient in 250. Myocardial infarction or symptoms of congestive heart failure each occurred in about one patient in 15. Atrial or ventricular dysrhythmias each occurred in about one patient in 150.
In post-marketing experience, there have been rare reports of exfoliative dermatitis caused by nifedipine.
There have been rare reports of exfoliative or bullous skin adverse events (such as exfoliative dermatitis, erythema multiforme, Stevens-Johnson Syndrome, and toxic epidermal necrolysis) and photosensitivity reactions.
Experience with nifedipine overdosage is limited. Generally, overdosage with nifedipine leading to pronounced hypotension calls for active cardiovascular support including monitoring of cardiovascular and respiratory function, elevation of extremities, judicious use of calcium infusion, pressor agents and fluids. Clearance of nifedipine would be expected to be prolonged in patients with impaired liver function. Since nifedipine is highly protein-bound, dialysis is not likely to be of any benefit.
There has been one reported case of massive overdosage with PROCARDIA XL Extended Release Tablets. The main effects of ingestion of approximately 4800 mg of PROCARDIA XL in a young man attempting suicide as a result of cocaine-induced depression was initial dizziness, palpitations, flushing, and nervousness. Within several hours of ingestion, nausea, vomiting, and generalized edema developed. No significant hypotension was apparent at presentation, 18 hours post-ingestion. Electrolyte abnormalities consisted of a mild, transient elevation of serum creatinine, and modest elevations of LDH and CPK, but normal SGOT. Vital signs remained stable, no electrocardiographic abnormalities were noted and renal function returned to normal within 24 to 48 hours with routine supportive measures alone. No prolonged sequelae were observed.
The effect of a single 900 mg ingestion of Procardia capsules in a depressed anginal patient also on tricyclic antidepressants was loss of consciousness within 30 minutes of ingestion, and profound hypotension, which responded to calcium infusion, pressor agents, and fluid replacement. A variety of ECG abnormalities were seen in this patient with a history of bundle branch block, including sinus bradycardia and varying degrees of AV block. These dictated the prophylactic placement of a temporary ventricular pacemaker, but otherwise resolved spontaneously. Significant hyperglycemia was seen initially in this patient, but plasma glucose levels rapidly normalized without further treatment.
A young hypertensive patient with advanced renal failure ingested 280 mg of Procardia capsules at one time, with resulting marked hypotension responding to calcium infusion and fluids. No AV conduction abnormalities, arrhythmias, or pronounced changes in heart rate were noted, nor was there any further deterioration in renal function.
Dosage must be adjusted according to each patient' needs. Therapy for either hypertension or angina should be initiated with 30 or 60 mg once daily. PROCARDIA XL Extended Release Tablets should be swallowed whole and should not be bitten or divided. In general, titration should proceed over a 7-14 day period so that the physician can fully assess the response to each dose level and monitor blood pressure before proceeding to higher doses. Since steady-state plasma levels are achieved on the second day of dosing, if symptoms so warrant, titration may proceed more rapidly provided the patient is assessed frequently. Titration to doses above 120 mg are not recommended.
Angina patients controlled on Procardia capsules alone or in combination with other antianginal medications may be safely switched to PROCARDIA XL Extended Release Tablets at the nearest equivalent total daily dose (e.g., 30 mg t.i.d. of Procardia capsules may be changed to 90 mg once daily of PROCARDIA XL Extended Release Tablets). Subsequent titration to higher or lower doses may be necessary and should be initiated as clinically warranted. Experience with doses greater than 90 mg in patients with angina is limited. Therefore, doses greater than 90 mg should be used with caution and only when clinically warranted.
No "rebound effect" has been observed upon discontinuation of PROCARDIA XL Extended Release Tablets. However, if discontinuation of nifedipine is necessary, sound clinical practice suggests that the dosage should be decreased gradually with close physician supervision.
Care should be taken when dispensing PROCARDIA XL to assure that the extended release dosage form has been prescribed.
Sublingual nitroglycerin may be taken as required for the control of acute manifestations of angina, particularly during nifedipine titration. See PRECAUTIONS , Drug Interactions , for information on co-administration of nifedipine with beta blockers or long-acting nitrates.
PROCARDIA XL® Extended Release Tablets are supplied as 30 mg, 60 mg and 90 mg round, biconvex, rose-pink, film-coated tablets in:
Bottles of 100:
30 mg (NDC 0069-2650-66)
60 mg (NDC 0069-2660-66)
90 mg (NDC 0069-2670-66)
Bottles of 300:
30 mg (NDC 0069-2650-72)
60 mg (NDC 0069-2660-72)
Bottles of 5000:
30 mg (NDC 0069-2650-94)
60 mg (NDC 0069-2660-94)
Unit dose packages of 100:
30 mg (NDC 0069-2650-41)
60 mg (NDC 0069-2660-41)
90 mg (NDC 0069-2670-41)
Store below 86°F (30°C).
Protect from moisture and humidity.
© 1997 PFIZER INC
69-4467-00-6 Revised March 1997

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After 23 rounds, the AFL Fantasy season is done and dusted. Record breaking scores and an amazing finish in the overall rankings, 2018 had it all.
Last year’s winner, Selby Lee-Steere, tied for first place with James Robinson as the pair tallied 52,308 points for the season. It came down to Robinson’s unique selection of Seb Ross in the final game of the round. A score of 123 would have seen him win the competition outright, 121 and it was a win to Lee-Steere. Ross finished on 122 and for the first time, first place was a tie in Fantasy Classic.
The joint winners of Fantasy Classic appear on the podcast as they share their stories of success. The nerve wracking moments throughout the last game of the round through to their best and worst moves of the season are revealed.
Roy and Warnie chat through the stories of 2018 including the players who were considered as the makers and breakers, sealing the fate of thousands of Fantasy coaches.
Study for next season has already kicked off with The Traders running their eyes over some names that they’ll be looking at over the off-season as they get ready to do it all again next year!
Click here to subscribe on iTunes. (Please leave a rating and review to help us move up the charts).
Fantasy points for and against – SEASON
Fantasy points for and against – LAST 3 GAMES

domain: news


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'This is a risk mitigation strategy,' B.C.'s top doctor said.
The province enacted the rent freeze at the beginning of the pandemic to support British Columbians who were struggling financially
Check your medicine cabinets.
Health officials say delayed start will give staff time to add additional protocols to reduce crowding
On Christmas Eve, B.C.'s top doctor clarified what you should do this year.
Not everyone will receive a PCR test. Here's why.
Not everyone should be travelling, says B.C.'s top doctor
Dr. Bonnie Henry says all parties are cancelled again this year.
Dr. Bonnie Henry has announced new rules for restaurants, gatherings and events.
'Records that are submitted and are suspected to be fraudulent are reported to law enforcement'


http://www.alliedtelesis.com/media/data ... cr1_ds.pdf
The AT-MCR1 is a single slot, rack-mountable
chassis, capable of housing any of the range of
Fast Ethernet and Gigabit Media Converters
and Bridging Media Converters.
standalone Media Converters and Bridging
Media Converters can be hot inserted and
removed from the chassis, thus removing the
need to power down the chassis for
maintenance and upgrades.


Tribe wants town to keep Native American in logo
FRANKLIN LAKES — Members of an Indian tribe want a northern New Jersey town to keep a Native American in its logo.
Franklin Lakes has asked residents to consider a logo with the depiction of the Native American and one without.
Borough Administrator Gregory Hart tells The Record newspaper 74 percent of the 900 respondents picked the logo without the Indian.
Dwaine Perry of the Ramapough Lenape Nation says there’s a vast difference between using a dignified image that represents native people and one that shows a caricature.
Hart says the town council hasn’t decided whether to change the logo, which would cost taxpayers to replace printed material.
Three of the town’s nearly 11,000 residents identify themselves as being American Indians or of Alaskan descent.


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The 1890s brought boom years to the nascent Aussie wine industry, as connoisseurs throughout Europe and the Empire were introduced to the Dionysian delights of new world Claret by Tyrrell, St Huberts and Wirra Wirra. An enterprising family of Scots took heed of the times to plant grapevines on a uniquely auspicious block in Valley Clare, they called it St Andrew and produced forty vintages of the most sensational quality Claret until the 1930s. The Taylor family acquired the fallow farm in 1995 and brought St Andrew's vines back to life. The treasured block endures as home to the flagship range of Taylor wines, one of the most distinguished vineyards in all Australia. St Andrew's Cabernet was adjudicated by Union de la Sommellerie Française as Best Cabernet..
*according to the french»
Established just eleven years after the founding of South Australia, the ancient vines in the Hundred Of Moorooroo were planted circa 1836 by the Jacob brothers, after accompanying Colonel William Light on the Seven Special Surveys expedition to populate Adelaide's north. Moorooroo endures as the nation's cardinal parcel of vine, the mother rootstock for many of the Barossa's most distinguished sites. For over a century, these sacred vines contributed fruit to the Orlando company, where they formed the backbone of countless spectacular historical vintages. Decimated by the government sponsored vine pull schemes of the 1980s, only four rows of these priceless vines were saved by master Ed Schild from complete annihilation. One of the smallest yielding blocks in..
The fruit of vines established 1836»
Clonakilla are one of our nation's most eminent vineyard wineries, a tiny production operation, established by a CSIRO scientist at Murrumbateman, very near Canberra. It turned out to be a fortuitous planting, with a climate not dissimilar to Bordeaux and northern Rhone, the Clonakilla property now occupies a rank next to the mighty Grange on the prestigious Exceptional Langtons Classification, it yields vintages of Australia's most invaluable Shiraz. At $26.99, the estate's entry level belies its stature and excellence within the pantheon of great Australian wine, an essential experience this week for all enthusiasts, a canny choice for shrewd and judicious aspirants of elite new world Shiraz...
Here's what our most picky pundits prefer»
Torbreck of Barossa are one of Australia's great export brands, synonymous with luxury and excellence throughout the world of wine. Crafted from the fruit of old and ancient vineyards, the opulence and exclusivity of Torbreck's painfully limited production challenge the primacy of Grange. Established by a share cropper in the 1990s, its precious range has risen to the status of First Growth amongst the community of ardent international advocates. Woodcutter is the entry level, assembled from parcels which may have been destined for some of the brand's lofty icons, an essential experience for all enthusiasts of compelling Barossa Shiraz...
Chew a chop of woodcutter's wine»
Major Sir Thomas Mitchell left more than just an invaluable bequeth of our nation's most detailed frontier maps. Mitchell distinguished himself in Wellington's army during the Napoleonic wars in the renowned 95th Baker Rifles. A gifted draftsman, he found his way to the nascent colonies of Australia, where his acumen at mapmaking won him the office of Surveyor General. During one of Mitchell's historical expeditions, he charted the fertile lands around Victoria's Goulburn Valley, establishing the colonial fruitgrowing township of Mitchell's Town. The district's auspicious orchards flourished until Colin Preece identified the region as an opportune place to grow world class wine. Vineyards thusly planted around the Goulburn billabongs, came to be known as Mitchelton. Now a half century of age, the vines remain..
Barriques between the billabongs»
William James Maxwell was an architectural sculptor who migrated from Scotland to Australia in 1875. He built a mock castle and established a family vineyard just outside Adelaide, which he named Woodlands Park. His son planted vines in nearby McLaren Vale and his grandson served a term as winemaker for Hardy Wines at the historic Tintara wineworks. William Maxwell's progeny remain in McLaren Vale, producing the southern hemisphere's most successful brands of Honey Mead, as well as vintages of the most extraordinary value in McLaren Vale Shiraz. But what does Maxwell taste like? Gentleman James Halliday describes Maxwell as robust, picking the eyes out of McLaren Vale shiraz; licorice, dark chocolate, savoury firm, ripe tannins, blackberry, positive oak the icing on the cake. Terrific value. Oh yes, he..
Made of mature vine mclaren vale »
It is an offence in Australia to supply alcohol to a person under the age of 18 years. Severe penalties apply to the supplier.
It is an offence in Australia for a person under the age of 18 years to purchase or receive liquor. Severe penalties apply to the procurer and the minor. Liquor Licence 57706940 | Wine is sunlight held together by water -Galileo | Drink More Wine in Moderation

domain: geography


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Well, I have finally completed a light box. It was really easy to do - I just followed the instructions that I found (with the help of etsy forums) at http://www.strobist.blogspot.com/.
I followed the instructions exactly and I spent $0 on the materials as I had everything on hand. Here is a picture of my new light box:
I'm still practicing with it though. It's harder than I thought it would be. I used a huge lamp yesterday to take some pictures and they came out kinda yellow. So today I took it outside and used natural light. I think those pictures came out better. I will post a before and after as soon as I get them uploaded to the computer. I was hoping the light box would keep me from having to depend on a bright sunny day to take my pictures. I'm going to keep working on it - I have to get better at this whole photography thing at some point. :)
Anyone have any tips or comments?? I would love to hear from you!


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Going on Our Honeymoon! No Shipments from July 10-27!!
The Moon Puppy Project
Women's Flip Sequin Backless Halter Top. Iridescent White and Gold Sequins
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Model Size 6, Cup size 34B. Custom made to order with chose flip sequin colors and lining. See all images for flip sequin color options. Fully lined with velvety fabric.
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Top reasons for taking aircraft engine on a stand
Maintaining aircraft engines takes various scheduled shop visits, depending on how long it is in operation. They prevent the majority of failures, but now and then aircraft engine has to be removed and put on the stand for unscheduled repairs. What are the main reasons (1) for such incidents?
Exhaust Gas Temperature (EGT) margin deterioration
EGT margin deterioration is often caused by the gradual increase in the clearance between the turbine blade tips and surrounding static seals or shrouds. Rate of deterioration is influenced by several factors – thrust rating, engine derate, average flight leg flown, ambient temperatures and environment (2). As deterioration increases, so does the fuel burn and gas flow losses, meaning that the overall efficiency of the engine gets significantly reduced.
For first-run engines in short-haul operations, this cause generates up to 50 per cent of shop visit removals while decreasing below 40 per cent. In medium and long haul operations, EGT margin deterioration cases increase in mature-run aircraft engines and make between 40-50 per cent of shop visit removals.
For aircraft engines in medium and long – haul operations, hardware deterioration can be as often a reason for removal as EGT margin deterioration. These mechanical problems occur after certain parts are exposed to extreme operating conditions for a prolonged period. They can result in blade distress (particularly on High-pressure turbine blades), parts cracking and chipping, and in extreme situations, part failures.
For engines in short-haul operations it’s still one of most often cases of shop visit removals, but twice rarer than for long haul operations, making about 20 per cent of removals.
Life limited part (LLP) expiry
While hardware or EGT margin deterioration depends on many external factors, life-limited parts have clear due-to dates and are required to be changed as soon as they reach the term. Aircraft engines in short-haul operations are more sensitive for this cause and in mature-run engines, it makes up to 60 per cent of shop visit removals. For medium and long haul operations, it takes around 10-20 per cent of the reasons for removal.
Have an AOG situation and are looking for an aircraft engine stand? Contact EngineStands.com
Whichever the reason for engine removal, you will need a reliable engine stand to hold it during the time off wing. At EngineStands.com we focus on delivering you on delivering an engine stand where you need it and when you need it in a fast and convenient way. Check our list of available stands or contact our team to learn more.


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What is the most important thing to remember when starting to think about new ideas? There is no one answer to this question as what is most important to remember when starting to think about new ideas will vary from person to person. However, some key things that could be considered include: finding a process for working on ideas, being open-minded and willing to experiment, and having enough confidence in your ideas.
looking for Fresh ideas for your unfinished basement ideas #unfinishedbasementwalls you’ve came to the right page. We have 8 Pics about Fresh ideas for your unfinished basement ideas #unfinishedbasementwalls like Fresh ideas for your unfinished basement ideas #unfinishedbasementwalls, DIY vinyl peel&stick flooring used for accent bedroom wall | Bedroom and also Fresh ideas for your unfinished basement ideas #unfinishedbasementwalls. Here it is:
Fresh Ideas For Your Unfinished Basement Ideas #unfinishedbasementwalls
Big ideas are the foundation of any successful business. They can be their own unique product, service, or idea, or they can be a combination of both. When it comes to big ideas, there are many different flavors and styles that can work well. No matter what your business model is, you need to find a way to capitalize on big ideas to grow and succeed.
Ideas For Covering Old Bathroom Tiles In 2020 | Tile Floor Diy
vidalondon grout thedecorformula.
the importance of creative art Creative art is important for many reasons. It can help children express themselves, develop their motor skills, and improve their problem solving abilities. It can also give adults a way to relax and de-stress. Creative art can be used as a form of therapy. It can help people work through their emotions, and it can be used to boost self-esteem and confidence. Creative art can also be used to teach people about other cultures and histories.
20 Gorgeous And Awesome Thanksgiving Table Decorations | Home Design
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The history of invention: From the ancient Greeks to the present day Inventions have a long and varied history, starting with the ancient Greeks. They were credited with developing many of the classic inventions such as the bow and arrow, pottery, and democracy. However, the modern era of invention has seen some significant advances, such as Apple’s iPhone and Google’s Street View. This article concentrates on three main invention ideas – air travel, automobiles, and satellite TV – but there are others that have long been inching towards becoming common knowledge.
15 DIY Cheap Patio Bench Ideas From Concrete Blocks - Dwell Of Decor
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Why do we need ideas? Ideas can be a powerful force when it comes to getting things done. They can also help us see the potential for something and come up with ways to make it work. But what happens when we don’t have any ideas? What do we do then?
Cheap Basement Flooring Ideas - House Plans | #135927
But innovation can be difficult to achieve. To be successful, companies often require a combination of innovative thinking, strong management skills, and the right resources.
DIY Vinyl Peel&stick Flooring Used For Accent Bedroom Wall | Bedroom
What is innovation? Innovation is the process of creating new ideas and technologies that solve problems. It can be found in everything from product development to business strategy. Innovation is what makes our world go round, and it’s what keeps us alive.
11 Small Apartment Balcony Ideas With Pictures | Balcony Garden Web
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Are you looking forDIY Ideas to improve your home? If so, then you are in the right place. In this article, we will be discussing 5 easy and affordable DIY projects that can help improve your home’s appearance. So, if you are looking to spruce up your home in no time, read on!
25 Indoor Wedding Decorations Ideas - Wohh Wedding
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How do you come up with good ideas? Ideas are a dime a dozen, but they often have the potential to be great. Here are three tips to come up with good ideas:
Take your time – don’t just give up on an idea right away. Start by thinking about it more closely and then coming up with potential ways that it could be improved.
Be open to feedback – If you don’t think your idea is good, ask other people for their opinions. This will help you get closer to the best version of your idea.
Be persistent – If you keep working on your idea, eventually it will become better.


Mark Ryan Biography
Born H.A. Der-Hovagimian in Toronto (Canada) of Armenian decent. He signed his first recording contract with newly-found at age 17. At 19, Billboard Magazine named him one of the top remixers from Canada. For years, his main focus was the project. Starting out as a solo techno project, and later crossing over with its commercial pop dance sound, the group (which consisted of Mark and schoolmate ) won numerous top ten hits and licenses worldwide, and peaked with its cover version of the 1980's hit "Forever Young". Mark left the group in 1997 and launched his own studio focussing on producing and/or remixing other local artists such as , , , , and many more.
In 2002 Mark launched his second studio in Yerevan (Armenia).


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I've been working on lots of different projects lately, so the contents of my sketchbooks have been pretty varied. The pages have been filled with pigeons, moons, fruit, turkish rugs and make-up brushes!
Here's a small selection of some of my favourite pages from the last few weeks:
If you want to keep up to date with what I'm drawing, I regularly share snaps of my sketchbook pages over on Instagram.
I'll be back on Wednesday with another new illustration to show you (those pages of drawings of moons will finally be explained!)


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Sen. Chuck Grassley, R-Iowa, expressed frustration Monday following the latest delay in the release of the DOJ’s inspector general’s report on FISA Court abuse against the Trump campaign.
Sen. Grassley: “All of the delays and excuses why the Horowitz IG FISA report isn’t public yet after several months of anticipation of its issues leads me to the suspicion it’s going to be ‘deep six’ [sic] by the deep state,” Grassley wrote on Twitter.
All of the delays and excuses why the Horowitz IG FISA report isn’t public yet after several months of anticipation of its issues leads me to the suspicion it’s going to be “deep six” by the deep state
— Chuck Grassley (@ChuckGrassley) October 22, 2019
The IG report was pushed back to last week but was not released.
And now there is no word on whether it will be released this week after last week’s delay.
Grassley suspects the Deep State may discard the findings and the public may never see the criminal activity taken by the Obama administration against the Trump campaign in 2016.
Last week former Republican lawmaker Jason Chaffetz suggested the delay was due to intra-agency squabbling over the proposed redactions. Chaffetz added that he has not seen any evidence that FBI Director Wray has been cooperative in the investigation.
Investigative reporter Paul Sperry suggests this may be an attempt by the Deep State intelligence community to run out the clock.
If President Trump is impeached before the IG report is released we may never see it.
3/3 The IG report along with all the classified docs are still being held back from the public. If impeachment beats their release, then you know the fix is in.
— Paul Sperry (@paulsperry_) October 17, 2019


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A Guide To Taking CBD Oil Products
If you are considering buying CBD oil products for bettering your health and wellness, you might be wondering how often you should be taking CBD in order to receive the benefits it has to offer while also not “overdoing it.”
As we touched on in our previous blog, there is no harm in using CBD frequently. But in an effort to conserve your CBD oil products and save money, you might want to find your ideal balance to receive the relief you need without going through your CBD oil tincture, capsules, or other forms of CBD too quickly.
Since CBD oil products are a part of a relatively new industry that is still being researched, it can be difficult to navigate the dosage specifications in order to determine how much CBD is right for you and your specific needs.
In order to provide some clarification and help you get the most out of your CBD products, we want to discuss how often you should be using CBD as well as how long the effects of CBD last for most users with the variety of products available today.
Every Person Is Different
Before we dive into how much CBD you should take, it’s important to understand how CBD works and that it can have a different effect with everyone. Depending on a variety of factors, such as your weight, metabolism, body chemistry, conditions you’re suffering, and more, CBD oil products work in varying doses and last for varying lengths of time. This is because each person’s endocannabinoid system — what regulates and maintains the balance of our physical and mental health — is unique, meaning each individual’s ECS can be affected in different manners.
Start Low And Go Slow
Just as you would with any other new supplement you’re introducing to your body, it’s important that you start with a low dosage amount in order to become familiar with exactly how your body responds to CBD. Once you have a general idea of how your body responds to it and how well it is benefiting your condition, you can gradually increase your CBD intake until you find that “sweet spot” where you receive all the marvelous benefits of full-spectrum CBD oil without going above and beyond.
How Much CBD To Take
CBD, just like many other supplements and pharmaceuticals, takes time to build up in your system and to be fully accepted by your endocannabinoid system as “one of its own.” This is why we recommend taking CBD as a daily supplement in order to allow it to become fully introduced to your internal biology and be given “permission to go to work,” in a sense.
According to WebMD, “CBD doses of up to 300 mg daily have been used safely for up to 6 months. Higher doses of 1200-1500 milligrams daily have been used safely for up to 4 weeks.”
When starting off with your specific CBD journey, we recommend starting with an amount around 15-25mg a day in your preferred form of CBD oil product. Monitor your results for a week or two, then start taking CBD at night as well, upping your CBD dosage to roughly 30-50mg a day. Always refer to the serving amount that is detailed on your specific CBD product; each one has different concentrations of CBD, meaning it will take less of the product to receive the benefits depending on how much is present. And, like we said, start low and go slow.
Typical Durations For CBD Effects
CBD Oil Tincture: Users typically begin to feel the effects of CBD within 15 minutes when using sublingual CBD products.
CBD Edibles: Edibles must be digested prior to entering your bloodstream, meaning they can take upwards of an hour to begin working, but they can provide benefits for up to 8 hours.
CBD Topicals: Topical CBD is absorbed directly into the skin upon application, but it can take 20-40 minutes before the effects are felt. They then last for 4-6 hours on average.
CBD Capsules: Like edibles, CBD capsules can take anywhere from 30 minutes to one hour to take effect and last up to 8 hours.
CBD Vape Oils: By vaping CBD, you receive almost immediate results, but the effects last only for roughly 30 minutes after inhalation, so you’ll want to periodically administer throughout the day.
From all of us at Agrozen Life Sciences, we hope that this information helps you get a better grasp on how to start taking CBD and which type of CBD oil product is best for you and your specific needs. Browse our online CBD shop today to start your journey to a better you and experiencing nature’s wellness!
*Note: The information presented above is intended to serve only as general guidance and is not medical advice. As with any nutritional supplement, speak with your doctor about possible drug interactions.