Data Communications and Networks: An Engineering Approach
Data Communications and Networks uses a top-down, Internet-focussed approach to tackle the problem of communication system design. An integrated approach is taken to networks and data communications, with an emphasis that starts from the top level requirements and works downwards, describing how such requirements are fulfilled by lower layers of the transmission chain. While the book contains sufficient detail to provide an excellent foundation, clarity is paramount and care is taken not to swamp the reader with information to the point where the underlying concepts are obscured.
The Internet is used as the principle example of a communication system, allowing the reader to follow the system from the application layers, with source coding and security, through the network, with naming and routing algorithms, down to transport and physical aspects of a communication system. Modern techniques such as mobile radio, Voice over IP, and ASDL, are covered, while more traditional aspects such as circuit switching, which still form a significant part of current systems, are not overlooked.
By providing a technical introduction and including application examples, this text will have significant appeal to final year students, postgraduates and professionals with a science or engineering background wishing to gain a basic understanding of the key concepts behind data communications engineering.
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acknowledgement additional algorithm Alice allows application attack bandwidth binary bits block bytes calculate called carried cell channel cipher circuit codeword combinations communication complex connection considering correct defined delay depends designed destination detect distance domain efficiency encoding encryption entropy error example field Figure flow frame frequency function given gives header host increase individual input layer length log2 maximum means modulation node occur operation output packet path performance physical possible probability problem protocol radio received reduce repeat result ring router routing sample scheme segment sent sequence server shown signal simple single standard switching symbols terminal token traffic transfer transform transmission transmitted transport types


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9 600 Arrested In Operation “Tame The Traffic Jungle”2 weeks ago
The number of people who have been arrested by the Police in the ongoing operation dubbed “Tame the Traffic Jungle” has risen to more than 9 600.
On Saturday, 16 September, Zimbabwe Republic Police (ZRP) spokesperson Assistant Commissioner Paul Nyathi said 4 307 vehicles have been impounded for moving on the roads with defects. He said:
The ZRP reports that a total of 9 673 arrests have been effected during the ongoing operation, “Tame the Traffic Jungle”. 4 307 vehicles have been impounded for moving on the country’s roads with defects, while 309 vehicles have also been impounded for moving on the roads with no registration plates.Feedback
Police are conducting the operation in conjunction with the Traffic Safety Council of Zimbabwe, the Vehicle Inspectorate Department, the Insurance Council of Zimbabwe, the Zimbabwe National Road Administration, the Zimbabwe Revenue Authority, and city and town councils.
Motorists whose vehicles were impounded have to obtain all the required vehicle documents to be able to be cleared by the Vehicle Theft Squad and the Vehicle Inspectorate Department, ZIMRA, among others, to get their vehicles back.
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The operation has resulted in a serious transport shortage and kombis have taken advantage of the situation to hike fares.
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domain: news


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Halloween is one of the most celebrated holidays for parties and games. From scary and spooky to trick or treat games you can find all sorts of fun Halloween printable games available online.
Halloween takes up a huge chunk of the essence of this lovely autumn month, and even though it comes literally on the last day of the month, it does set the tone for the entire month. Halloween isn’t just about dressing up and getting candy – there are plenty of games to be played and winners to be made! From candy bar trivia to spooky scavenger hunts, the printable Halloween games are perfect for any age. If you’re the host of a Halloween party, Halloween games are an absolute necessity!
We’ve some spellbinding, easy-to-print, October-centric games, starting with an obvious collection: Halloween. We’ve got games here that will certainly maintain the almost sacred spookiness of Halloween. Perfect for Halloween get together and parties for any age bracket.
The games are easy to print and you can use them year after year. They range from trivia games to spooky games and fun games for kids and adults.
With these incredible print game service, you have endless amounts of party games at your disposal!
Easy to print, fun to play, and reusable, you’re sure to find a few party games you love.
- How to Go Green Earth Breeze’s Laundry Detergent Eco Sheets for a Stress-Free Holiday Season
- New eBook Download Printable Profits: 50 Creative Ways to Make Money Online with Digital Downloads
- How to Save Money and Dry Laundry Faster with Wool Dryer Balls
- Discover the Ultimate Solution: Ortho-Cushion™ System for Plantar Fasciitis Relief
- Where to Find the Best Battery Powered Halloween Animatronics

domain: hobby


Secret Service is a legendary Swedish pop/new wave band, originally formed 1979. Ola Hakansson, former vocalist of Ola & The Janglers and then a publishing manager at Sonet Music, teamed up with Tim Norell and Ulf Wahlberg to write a few songs that they submitted to the European Song Contest. They did not win but decided to continue working together and changed their band's name from Ola+3 to Secret Service. Besides Ola Hakansson (vocals), Tim Norell and Ulf Wahlberg (keyboards), the original lineup included Tonny Lindberg (guitars), Leif Paulsen (bass) and Leif Johansson (drums).
Tim Norell however, who along with lyric writer Bjorn Hakanson, penned most songs of the band, did not appear with the band on stage or on the album covers. Secret Service's first single "Oh Susie" became a hit in Sweden and several other countries of Europe and South America. "Oh Susie"was no 1 in 29 countries.
The same titled album included another hit, "Ten O'clock Postman" Other successes followed, with their synthesizer based number "Flash in the Night" hitting the charts all over continental Europe, the duet with ex-ABBA's Agnetha Faltskog, "The Way You Are", also to be mentioned.
SECRET SERVICE – NEW RELEASE ”SECRET MISSION”
Now it’s time for the second song in the new Secret Service project ”Four Seasons” to be released. ”Secret Mission”, a melancholy creation in classic Secret Service style, about alienation and trust when the rest of the world turns away. As always written by hit master Tim Norell.
”Secret Mission” is a mix of modern sound and 80s synthesizers, delicately arranged by Anders Hansson who became member of the group in 1986.
Intensive lead vocals by new singer John Becker and of course with Tim and Ulf Wahlberg on backing vocals.
TITEL: ”Secret Mission”
ARTIST: Secret Service
MUSIC & LYRICS: Tim Norell
ARRANGEMENT: Anders Hansson
PUBLISHER: Goldberry Music
COMPANY: Tim Norell Musikproduktion AB
Listen "SECRET MISSION" in:
Secret Service — Secret Mission (OFFICIAL VIDEO, 2020)


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Public opinion and political action essay
Accountability through public opinion : from inertia to public action / [edited by] research focuses on issues of public opinion, the public sphere, and political. Public opinion can have which allow us to see exactly where every penny of our taxes is going and opens up the space for political and public debate on. Public opinion and political action essay the mean increasing in walking distance achieved about patients the truth egb 761 (a ginkgo biloba preparation. Essay on public policy & social the problem of illegal immigration came to public and political awareness because of conflicting public opinion and impact on.
Public sphere by “the public sphere” we mean first of all a realm of our social life in which something approaching public opinion can be formed. Chapter 6: public opinion and political action chapter summary i the american people (174-180) introduction the study of public opinion aims to understand the. 103 chapter 6 public opinion and political action chapter outline i the american people (pp 181-187) a public opinion: the. View test prep - public opinion and political action study guide from ap governm comparitiv at douglas county high school, minden chapter 6 study guide 1 census.
Ap government review public opinion and support for political you can make a global statement at the beginning of your essay that shows that you know. Power and the news media 10 political communication in action ask their opinion, and thus introduce them as major news actors or. Ch 6 public opinion & political action 1) it will be posted here 2) essay questions what is public opinion.
Public opinion essays: over vietnam essay public opinion the us withdrawal : a survey of public opinion of gun policy in wisconsin affirmative action: public. Essay on political socialization of moulding and shaping public opinion propaganda they mobilize political action and offer a choice to the electors to. The role of salience on the relationship between public policy and public opinion by groundswell for positive action public opinion for for political. What is public opinion public opinion is and other political actors politicians look to public opinion to despite the limitations of public opinion.
Free public opinion of the public sphere - in this essay i will discuss jürgen participation of discussion and action in political.
2013 review of scholarly studies that examine the intersection between public opinion and rulings of the supreme court. Public opinion reviewing the chapter chapter focus public opinion 2 political scientists and blacks more likely to support affirmative action (2. The essay describe public policy happens when the government tries to it occurs in political parties, and campaigns and the general public opinion. This essay addresses three views of policy responsiveness to public opinion in the policy responsiveness to public opinion political economy of. And how public opinion becomes political action as actors in the political public sphere transformations of the public sphere essay forum. Public opinion and political action students should have a thorough understanding of the role and limits of public opinion and political essay questions. Define the term interest group and distinguish these groups from other political organizations citizen action groups, also known as public interest groups.
1 definitions the term ‘civil disobedience’ was coined by henry david thoreau in his 1848 essay to describe his refusal to pay the state poll tax implemented by. The political opinion and behavior of individual participation of discussion and action in political platforms that shape the public opinion. Public opinion definition, the collective opinion of many people on some issue, problem, etc, especially as a guide to action, decision, or the like see more. Most of what public relations is devoted to is repairing negative public opinion about individuals from political activism, we have the adage action speaks.

domain: sociology


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Joker Plus IIReal winners can now show their best poker face! With the popular 3-reel game Joker Plus II you enjoy games, fun and excitement. You don't just have the opportunity to double your winnings, but also the opportunity to get more from your winnings thanks to the joker. A winner's smile is guaranteed to appear on even the best of poker faces!
- 3 reels
- 27 paylines
- Joker: The joker is a replacement for other symbols.
- Double Win: Double your winnings with nine identical symbols!
- Triple Joker Special: With three jokers in one row, you get the winnings for each symbol.
- Joker Plus: Each winning combination with a joker leads to higher winnings.
- Gambling: Astronomical winnings can be achieved by multiple doubling of winnings after the game. After each game won, gambling starts. Winnings can be doubled in various rounds. There is also the security stage which acts as an extra part of the game: if the blue symbol appears, the actual amount of winnings cannot be lost in the rounds which follow.


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In CCR’s Laboratory of Cell Biology, Kandice Tanner, Ph.D., and her team are watching human cancer cells travel through the bodies of small, translucent fish. As the cells make their way through the animals’ circulatory systems to reach organs where they can establish themselves and begin to grow, the researchers are learning about the factors that drive cancer’s spread through the body.
Tanner, postdoctoral fellow Colin Paul, Ph.D., and colleagues report in the August 21, 2019, issue of Cell Systems that they have used zebrafish to discover that the particular sites colonized by migrating tumor cells are determined by both the physical architecture of tissue and the cells’ molecular compatibility with their microenvironment.
Metastasis, the spread of cancer away from a primary tumor to new locations in the body, is an unpredictable and potentially lethal process. It is not random: Cancers of the same type tend to metastasize to certain locations. When breast cancer spreads, for example, it most often makes its way to a patient’s bones, brain, liver or lungs. It’s not known, however, to what extent tumor cells are programmed to seek out particular sites, and currently there is no way of knowing where an individual patient is most likely to develop metastatic lesions.
Dr. Tanner is particularly interested in how cells sense, respond and alter their physical surroundings. She and her colleagues turned to zebrafish to study the early events in cancer metastasis because the tiny, transparent bodies of living zebrafish larvae can be viewed in their entirety under a microscope, making it possible to follow the movements of individual cells wherever they go. “The zebrafish is a powerful tool because we can follow the same cells in the same animal over several days,” she says. “We can get quantitative data to really understand what drives non-random organ targeting.”
Working with Raman Sood, Ph.D., who heads the Zebrafish Core at NIH’s National Human Genome Research Institute, Tanner’s team injected human cancer cells into the circulatory systems of developing fish when the animals were just a few millimeters long. Over the next five days, they monitored the cells as they moved through the circulatory system and some made their way into either the brain or a structure called the caudal vascular plexus (CVP), an environment that Tanner says is functionally similar to bone marrow. The cells the scientists used for their experiments tend to develop into tumors in the brain and bone marrow in mice as well, suggesting they behave similarly in the fish and in mammals.
Physically, Tanner says, blood vessels in the brain are different from those in the CVP. In the brain, tumor cells travel through straight and narrow vessels, whereas in the CVP, they follow a more variable, twisted path. The researchers found that migrating tumor cells were more likely to stop their journey amidst this relative chaos than they were to become arrested in the brain. Once the tumor cells’ movement had stalled, some managed to work their way out of the blood vessels into surrounding tissue. The team showed that this step, which is essential for metastatic tumor cells to begin to colonize an organ, was dependent on a cell’s molecular makeup with certain cells being better suited to invade the CVP and others establishing themselves more readily in the brain.
Tanner and her colleagues found that by genetically manipulating the tumor cells that preferred the brain, they could make those cells go to the CVP instead. With a deeper understanding of the factors that drive the early events in metastasis, it might one day be possible to redirect circulating metastatic tumor cells in patients at the time their primary tumors are treated, she says. Such an intervention could ensure that if new tumors arise, they will be more likely to occur in sites where they will be less harmful or easier to treat.


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Removing the decoration, the surface is naked. A blank space waiting for an identity.
The identity originates from the cooperation of a pool of artists and designers, who work in a continuous exchange of ideas and suggestions from each sector of our experience: fashion, art, design, architecture, urban buildings, natural materials, textiles etc.
A complete outfit for the rooms (floor, wall, ceiling, pieces of furniture): Inkiostro Bianco can give a completely new look to every space. Every project is a unique experiment carried out with proficiency and extreme care for details. An expert advice is the first step towards the expression of your own style: the total look of the surfaces determines a radical and unexpected change.

domain: artistic


Cancer Services Program of Sullivan County
845-794-3300 ext. 2794
Cancer Services Program of Sullivan County provides free breast, cervical and colon cancer screening to uninsured and under-insured men and women in Sullivan County.
Available Screening Tests
Breast Cancer Screenings
Over the past decade, the Cancer Services Program (CSP) of Sullivan County has helped hundreds of women without insurance get screened for breast cancer. The mission of the CSP is to ensure that women, despite insurance status, have access to mammograms and breast exams.
Clinical breast exam every year for uninsured women over 40 (women under the age of 40 who are at high risk for breast or cervical cancer may also be eligible for screening.)
Colon Cancer Screenings
Colon cancer is one of the single cancers that can be treated and beatable. Adults who are at average risk are recommended to talk to their doctor about colorectal screening at age 50. One of our goals at Cancer Services Program of Sullivan County is to have 80% of New Yorkers screened by the end of 2018.
Screening mammogram every year for uninsured women over 40.
Pelvic exam with Pap test every three years for uninsured women over 40.
Upcoming Screenings and Informational Sessions
As part of our commitment to educating and keeping our community members healthy, we often hold screenings and informational sessions that are free for all and/or for eligible individual based on health risks. Below you will see upcoming sessions and screening, as we have them schedule.
New dates are being schedule throughout the year, so if there are none currently available, please check back soon! If you have any questions, please call us at: 845-794-3300 ext. 2794
Assurance of Follow-up Based on Test Results
If the screening test finds something abnormal, our program pays for further testing and provides a case manager who guides clients through those follow-up appointments. Diagnostic tests (diagnostic mammogram, sonogram, colonoscopy, breast or cervical biopsy, surgical consults), for clients whose screening exams suggest that further testing is required.
If treatment is needed, support is given to help individuals apply for New York State’s Medicaid Cancer Treatment Program. Some of the support you can look to the CSP for would include:
- Recommendations about further diagnostic testing
- Counseling on medical care that may be required
- Help in making appointments and arranging transportation to and from doctor visits
- Appropriate referrals to health and human service agencies as necessary
- Assistance with enrollment in the Medicaid cancer treatment program for financially eligible clients who are diagnosed with breast, cervical or colon cancer
Cancer Screenings: Participating Locations
Cancer Services Program of Sullivan County contracts with many local physicians and nurse practitioners to provide services to our clients. The New York State Department of Health (NYSDOH) has credentialed each of these health care providers to perform breast exams, Pap tests and pelvic exams. Some of our current providers throughout Sullivan County, include:
- Primary Care (CRMC): Concord Rd Monticello, NY 12701
- Bethel Medical Center: 1522 Route 17B White Lake, NY 12723
- Hudson River Health Care: 19 Lakewood Ave Monticello, NY
- Callicoon Family Health Center: 8881 State Route 97 Callicoon, NY 12723
- Livingston Manor Family Health Center: 36 Pearl St. Livingston Manor, NY 12758
- Middletown Medical: 653 Ferndale Rd. Ferndale, NY 12734
- Youngsville Medical Center: 4054 State Rt 52 Youngsville, NY 12791
Please call us at 845-794-3300 ext. 2794 to see if your primary care physician works with our program.


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Trophos Successfully Completes Phase Ib ALS Clinical Trials for TRO19622, a Novel Compound to Treat Neurodegenerative Disease
One-month study shows good tolerance and exposure levels to drug, together with an excellent safety profile with once a day oral dosing, and paves the way for a Phase II/III pivotal trial in ALS
MARSEILLE, France, Dec. 7, 2006 - Trophos, a biopharmaceutical company specializing in the discovery and development of drugs for neurodegenerative diseases, announced today the successful completion of Phase Ib clinical studies for its lead compound TRO19622. The completed studies include a one month compliance, tolerance and safety study conducted in 36 ALS patients at doses of 125 mg, 250 mg and 500 mg administered orally, once a day, plus two drug-drug interaction studies conducted in healthy volunteers. TRO19622 is in clinical development for motoneuron diseases, amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease) and spinal muscular atrophy (SMA), as well as for painful diabetic neuropathy.
The studies demonstrated that, in ALS patients, TRO19622 is well tolerated and exceeded the exposure level predicted to achieve efficacy via the oral route at doses superior or equal to 250mg per day. In healthy volunteers, TRO19622 exposure levels were approximately 30% higher after repeated dosing with riluzole for which bioequivalence was shown before and after repeated dosing with TRO19622. In these three Phase Ib studies, TRO19622 continues to demonstrate an excellent clinical safety profile in all subjects receiving drug substance.
The successful completion of these Phase Ib studies will enable Trophos, subject to regulatory approvals, to initiate a pivotal Phase II/III clinical trial to evaluate TRO19622 efficacy (survival and functional benefits) in the ALS indication, to be conducted at approximately 10 centers in Europe. Trophos is currently seeking a co-development/licensing partner for this program in the US. In addition, Trophos now expects to initiate a European Phase Ib clinical study to assess the tolerance and safety of TRO19622 in juvenile SMA patients in the first half 2007.
TRO19622 is representative of a class of novel compounds identified using the proprietary neuronal cell-screening platform developed at Trophos. In preclinical studies these 'first-in-class' compounds have been demonstrated to promote the survival of a wide range of neurons in vitro, as well as in several in vivo models of neurodegenerative diseases.
"We are excited that TRO19622, the lead molecule discovered using our innovative phenotypic screening platform has successfully completed these Phase Ib trials and continues to demonstrate an excellent clinical safety profile," said Dr Jean-Louis Abitbol, Chief Medical Officer at Trophos. "Completion of these studies will allow Trophos to proceed to assess the clinical efficacy of TRO19622 in ALS patients, in terms of both survival and functional benefits. In addition, the excellent safety profile of TRO19622 paves the way for further clinical studies to assess the efficacy of TRO19622 in juvenile SMA patients."
About ALS (Amyotrophic Lateral Sclerosis): ALS, more commonly known as Lou Gehrig's disease in the USA, is a progressive and fatal neurological disease that is estimated to affect over 100,000 people worldwide. There is no cure for ALS. The only drug approved for ALS is riluzole (Sanofi-Aventis), which has been demonstrated to give some survival benefit to ALS patients. For more information about ALS, see www.alsa.org
About SMA (Spinal Muscular Atrophy): SMA is a genetic disorder that affects muscle movement in approximately 1 in 6000 live births. It causes the motor neurons in the anterior horn of the spinal cord to deteriorate thereby gradually weakening the voluntary muscles used for activities such as crawling, walking, sitting and moving the head. SMA is classified into four types, based on the age at which it develops and the severity of the symptoms. Types I, II and III develop in childhood while Type IV starts in adulthood. There is no cure for SMA. For more information about SMA, see www.fsma.org
About Trophos: www.trophos.com
Trophos is a biopharmaceutical company developing drugs to treat neurodegenerative diseases. These are severely debilitating, often fatal, disorders with few effective drugs and tremendous unmet medical needs. In preclinical studies, compounds with similar effects as TRO19622 have been shown to prevent the neuronal degeneration that is involved in the onset or progression of motor neuron disease. The motoneuron disease program at Trophos is supported, in part, by the Association Francaise contre les Myopathies (AFM, for more information see www.afm-france.org)
. Trophos was founded in 1999, is based in Marseille, France and currently has 32 employees.
-- Neil Hunter ANDREW LLOYD & ASSOCIATES http://www.ala.com firstname.lastname@example.org
Andrew Lloyd & Associates Andrew Lloyd / Neil Hunter Tel: +44 1273 675100 email@example.com
Brighton Business Centre 95 Ditchling Road Brighton BN 1 4ST ENGLAND Tel : +44 1273 675100 Fax : +44 1273 675400
55 rue Boissonade 75014 PARIS FRANCE Tel : +33 1 56 54 07 00 Fax : +33 1 56 54 07 01

domain: medical


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Sevier County, my beloved home, has gorgeous mountains, great people, an abundance of tourism and a tidge of the old ways... as in the good old boy ways. An audit by the Tennessee Comptroller of the Treasury peeked at the books of Sevier County government for the fiscal year ended June 30, 2008 and everything ain't perfect. Who'd a thunk it?In tomorrow's column
, I sniff around the edges of the audit and detect a whiff of smoke here in the foothills of the Great Smokies. And where there's smoke...
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domain: finance


You are required to find the appropriate size of an air conditioning machine to be installed in a space of your choice in a location of your choice to cool it in the summer. It is preferred to select a simple space. but in the meantime the space must be subjected to all the internal and external thermal loading element we discussed in class (i.e., external: conduction through external walls, conduction through internal walls, conduction through glass window, solar radiation through glass window, infiltration through window and door. Internal: people, lighting, equipment thermal loading. Ventilation requirement). Your task is to find these loads (plot the variation) over 24 hours period throughout the year to find the maximum value of each, as well as you need to find the total load over the 24 hours throughout the year (monthly) to find the maximum value of the sum of the thermal loading. Based on this info you will decide what size air condition need to use in that space.


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If you suffer from regular sore throat bouts and are searching for some useful and helpful home remedies, then we’re here to support. Sore throats can be unpleasant and often are the first symptoms of a cold. So check how to get rid of a sore throat in a day.
A sore throat refers to the discomfort, itchiness or throat annoyance. You can have difficulty consuming food and drinks, so as you cough, the discomfort can get stronger. Either a viral infection or a bacterial infection may cause this. The symptoms of a sore throat may vary according to what it caused. Can feel a sore throat:
- Burning of throat
- Red Tonsils
Home remedy to get rid of a sore throat:
So here are a few of our top tips to help you easily get rid of it, including honey, salt water, ginger and lemon.
1. Salt Water
This is one of the popular and simplest home remedies for sore throat, advised by even the grandma. Gargling several times a day in salt water tends to minimize inflammation in the throat and removes the mucus that serves to filter out the bacteria. Add half a tablespoon of salt to a cup of water. Give a little drop of honey if the salt is too much. Also spit out the water after gargling, just don’t drink.
Because of its effective antibacterial properties, Honey is used to get rid of a sore throat throughout India. Honey also serves as a wound healer, providing instant relief for discomfort and helping to reduce inflammation. It can kill bacteria as well as help prevent viral infections. In addition to a sore throat, if you suffer from a bad cough, honey will also serve as an effective medicine. In a glass of water or tea, add two teaspoons of honey, and stir well. Drink it as required many times a day.
Similar to salt water and honey, lemons are great for sore throats, as they can help break down mucus and relieve pain. Moreover, lemons are packed with vitamin C that can help boost the immune system, and provide it more power to fight off your infection. Mix in a glass of warm water a teaspoon of lemon juice and drink for quick relief. In a glass of warm water, add a tablespoon of lemon juice and drink for immediate relief.
Ginger is a spicy, pungent herb used to cook and, sometimes, to cure. One medicinal use of ginger, which is supported by both studies and tradition, is to treat sore throat & voice issues. Ginger can be helpful in several ways to sore throats. As an anti-inflammatory, for example, it may offer some pain relief. It improves immunity to better prevent sore throat infections.
Another fast remedy that you’ll love for sure? Scoop up some of your favourite ice cream, several physicians recomend that. Everything that is frozen — ice itself, popsicles, frozen cream — numbs skin and nerves and also decreases discomfort, according to physicians.
So with these simple solutions at home — that take just minutes! — No reason to let the sore throat slow you down.
If you really like our article then share it and follow us on Twitter.


Escort Radar’s New M1 Dashcam
- M1 has been replaced by the new Escort M2.
The First Dashcam by Escort Radar
Escort M1 dashcam offers Escort radar detector users peace of mind when it comes to ease of installation without any additional hardwiring. M1 dash camera mounts directly onto a compatible Escort radar detector with StickyCup or EZ-Mag Mounts, with minimal modification involved.
Escort M1 Dashcam Features
- 1080p FullHD quality, enhanced night vision, and wide-dynamic range (WDR)
- 160 deg viewing angle
- Continuous loop recording
- Emergency recording – automatic / manual
- G-sensor built-in
- 16GB micro-SD card included
Compatible Radar Detectors
- With included StickyCup or EZ-Mag Mount: Escort iX, iXc, Max360, Max360c, Redline EX, Passport Max, Max2, Beltronics GT7
- With optional StickyCup Mount: Beltronics Pro-Series, STi Driver, STi Magnum, Escort X70, X80, Solo Series
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Bacterial Slime Flux Treatment Fort Worth, Texas
Tree Care Pros provides Fort Worth clients both commercial and residential Bacterial Slime Flux Treatment in Fort Worth, TX and surrounding Dallas Fort Worth regions. Slime flux disease also known as bacterial wet-wood is caused by numerous varieties of bacteria that are prevalent in soil and water. The specific type of bacteria linked to slime flux disease depends upon the variety of tree the disease invades. Fort Worth trees targeted by slime flux include cottonwood, fruitless mulberry, elm, oak, sycamore, maple, cherry, ash, poplars and many others. The bacteria infects the tree via wounds and natural cracks and splits along the tree’s trunk. Slime flux bacteria feeds on nutrients found within the tree sap, and an arbor care professional can immediately identify this culprit by the watery, filmy liquid running down the trunk from damaged areas on the tree bark. The infected tree will exhibit varying colors of vertical streaks from this leaking fluid. The liquid is actually fermented sap and is the reason for the strong, unpleasant stench. A certified arborist has extensive knowledge pertaining to this common Fort Worth tree disease, and is highly skilled and able to conduct diagnostic testing and confirm the presence of bacterial wet-wood disease. For Bacterial Slime Flux Treatment in Fort Worth, TX, call (817) 402-2055 for a free bacterial slime flux treatment diagnosis by a certified arborist.

domain: biology


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Author Contributions: Dr Lin had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Lin, Hota, Woeltje, Stevenson, Weinstein, Trick.
Acquisition of data: Lin, Hota, Khan, Borlawsky, Doherty.
Analysis and interpretation of data: Lin, Hota, Weinstein, Trick.
Drafting of the manuscript: Lin, Trick.
Critical revision of the manuscript for important intellectual content: Lin, Hota, Khan, Woeltje, Borlawsky, Doherty, Stevenson, Weinstein, Trick.
Statistical analysis: Lin, Trick.
Obtained funding: Woeltje, Stevenson, Weinstein.
Administrative, technical, or material support: Lin, Hota, Khan, Borlawsky, Doherty.
Study supervision: Lin, Hota, Weinstein, Trick.
Financial Disclosures: None reported.
Funding/Support: This study was funded by CDC Cooperative Agreements U01-CI000327, U01-CI000328, and U01-CI000333 from the CDC Prevention Epicenter Grants.
Role of the Sponsor: The sponsors had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; and preparation, review, or approval of the manuscript.
Previous Presentation: Presented in part at the 18th Annual Scientific Meeting of the Society for Healthcare Epidemiology of America, Orlando, Florida, April 6, 2008 (Abstract 346).
Additional Contributions: We thank the infection preventionists who contributed their surveillance data to the analysis.


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Mummies Alive, a new historical documentary series, is coming to the Smithsonian channel. Broadway World is reporting that Mummies Alive will premiere tonight. The TV series was originally ... See full summary »
The Transformers' war continues in an older time, through a new generation. On pliocenic Earth, the heroic Maximals and the evil Predacons battle for survival against each other and against a violent planet.
Ian James Corlett

domain: entertainment


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In the journey of life, there are several occasions when you will be required to borrow money from banks. It may be for purchasing a home, car, or getting a Loan Against Property to fund your big-ticket financial needs. Either way, when you borrow it is imperative that you exhibit the traits of a responsible borrower. This will not only help you build and maintain a healthy relationship with your lender, but will also ensure that the next time you need to take credit, it will be easily available.
In a bid to help you in this endeavour, we have collated a list of 5 tips that will help you inculcate the habits for mature borrowing!
Self-awareness needs to be your go-to means when it comes being a good borrower. Before you opt for Taking a Loan Against Property, Personal Loan or any other form of credit you should carefully analyse your financial standing and weigh the money you already have against the money that you require.
See, if you truly need additional funds, or if you can manage the expenses with the help of your current savings. If you need to take a loan, make sure you only apply for the amount that you need and nothing more than that! Remember, a loan accrues interest, and if you already have the resources, taking a credit may unnecessarily increase your financial burden.
Regardless of the amount of money you have borrowed as a loan, make sure you take full responsibility for your obligations. Wondering how to do that? Well, you can start by ensuring that you pay your equated monthly instalment (EMIs) on time. Then again, as far as possible, don’t use any excuses to delay or default your payments. The more compliant you are towards the repayment of your loan, the easier it will be to become worthy of the trust of the lenders, thus helping you nurture a strong relationship with them.
As a matter of fact, to be a responsible borrower, it is suggested that you have at least 6 months’ worth of your business and living expenses as your savings. Having this cushion not only helps you put a strong front for lenders, but also helps you pay your EMIs in times of distress.
Loans are great when you need financial assistance, but so are other means of revenues such as a part-time job, some simple ways that can help you cut costs in your business, or a consistent habit of saving money for the rainy days. These sources can conveniently help you in meeting short-term expenses, which require a competitively small amount of money! By taking care of such expenses on your own, you can ensure that you do not have too many loans under your name, thus assuring lenders of your financial discipline, when you apply for a loan of more significant nature!
We cannot stress this enough! Once you take a loan, it is your onus to pay your EMIs on time. Just in case, you’re unable to make a payment on time contact your lender, and convey the same. More often than not, the lender will make the requisite adjustments so that your credit rating doesn’t get hurt in the process. Besides, this simple act will help your lender see you as a dependable borrower.
However, make sure you don’t delay your payments too often. Since you already know about your obligations towards the lender, cut down on other expenses to make way for EMIs. For your credit history to be ideal, it is best that you don’t skip or delay even a single payment. And with some efforts, you can surely take care of the same.
It is evident that any lender would only want to give a loan to someone who they can place their trust in. Hence, it is strongly recommended that you prove yourself as trustworthy over time. If you take a loan for the first time and repay it sincerely, the lender will be more than happy to assist you, the next time you are on the lookout for some credit.
We hope that you are now aware of some easily comprehensible tips that can help you become a responsible borrower. And now that you know the importance of repaying your loan as stipulated in your loan agreement, wait no more before you start your hunt for the best Loan Against Property offers or other credit to fund your financial needs.
To apply online for Credit Cards, Secured Loans and Unsecured Loans, visit www.mymoneymantra.com, the leading online lending marketplace that offers financial products from 70+ Banks and NBFCs. We have served 2 million+ happy customers since 1989.

domain: economics


text:
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Sanders says White House has no recording of Trump's call with widow
White House press secretary Sarah Sanders said the White House does not have a recording of President Trump's call with the widow of fallen U.S. soldier Sgt. La David Johnson, after Mr. Trump claimed he had "proof" of the conversation. The call has become a point of intense controversy, after Rep. Frederica Wilson, D-Florida, said Mr. Trump told Johnson's widow, Myeshia Johnson, her husband "knew what he signed up for." During Wednesday's press briefing, Sanders did not dispute the details of Wilson's account, although she said she would not divulge the details of the president's private conversation. CBS
VOA VIEW: So what if the President made the statement.
Out It'll Be Congress's Fault If the Stock Market Crashes
Don’t take credit for the stock market, President Donald Trump is often warned, you’ll be blamed when it crashes. Well, maybe that can be avoided, too. With the help, specifically, of Congress, which Treasury Secretary Steven Mnuchin warned must pass tax cuts or be saddled with a correction in equities after their 20 percent jump since Election Day. His words came a day after Trump tweeted pictures of the Dow Jones Industrial Average crossing 23,000 for the first time. Call it cynicism, a reasonable bear case, grandstanding or even genius itself, just don’t call it out of character for an administration whose obsession with share prices seems to swell with every record close and each legislative failure. This $2.5 trillion bull market is rapidly becoming the one bounty it can’t go without mentioning, even for a day. Bloomberg
VOA VIEW: Who else?
tax strategy: Cut a few compromises but don't count on Democrats
President Trump's upcoming push for his tax cut plan next month will include compromises that will limit some of its current benefits for the nation's richest taxpayers, according to White House officials. The compromises will include ending a 23.8% preferential tax rate for hedge-fund managers, or the so-called carried interest rate, White House legislative affairs director Marc Short told USA TODAY. "He's not just open to it," said Short. "I would say, frankly, he wants it," he said. Retaining parts of a state and local tax deduction that benefits many middle-class families in blue states is also an area where Trump is expecting compromise as House Republican negotiators hash out legislation capable of winning the support of a number of party members representing high-tax blue states like New Jersey and New York, said Short. USA Today
VOA VIEW: Time will tell what the final product will be.
Executive Is Named to Run SEC Trading and Markets Unit
A JPMorgan Chase & Co. executive was picked to run the Securities and Exchange Commission unit that regulates U.S. stock markets and Wall Street brokerages. Brett Redfearn, head of market structure at the New York-based bank, will oversee the SEC’s trading and markets division, according to a statement from the regulator Wednesday. Bloomberg News broke the news earlier. The position has been open since January. The group deals with some of the most pressing matters facing the agency, including overseeing the construction of a massive trade database being built to help U.S. regulators police the stock market, as well as writing rules for exchanges and dark pools. Bloomberg
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and DeKalb officials join forces for sales tax vote
CEO Mike Thurmond, surrounded by mayors and government officials, speaks about ballot measures to increase sales taxes and cut property taxes during a press conference at the DeKalb Roads and Drainage Division on Wednesday, Oct. 18, 2017. Elected officials from across DeKalb County and its cities are coming together around referendums to raise sales taxes and reduce property taxes. DeKalb CEO Mike Thurmond and several mayors said during a press conference Wednesday that the ballot measures would create the county’s first special purpose local option sales tax (SPLOST), raising the sales tax rate to 8 percent. It would fund road repaving, new fire stations, more police cars and other infrastructure. Atlanta Journal
Vegas security guard breaks silence on 'Ellen' after disappearance
Mandalay Bay Resort and Casino security guard Jesus Campos, who has been hailed for being the first to confront Las Vegas shooter Stephen Paddock, gave his first public account of the attack, in an interview on "The Ellen DeGeneres Show." Campos and Mandalay Bay building engineer Stephen Schuck were DeGeneres' guests in an interview taped Tuesday. "As I was walking down [the hallway], I heard rapid fire," Campos told DeGeneres in the interview. "I took cover, and I felt a burning sensation. I went to go lift my pant leg up and saw blood. That's when I called in on my radio that shots were fired." The show released an eight-minute clip of the interview on Tuesday night, and the full episode will air Wednesday afternoon. ABC
VOA VIEW: Campos is trying to profit by what happened.
General Jeff Sessions says he has not been interviewed by special counsel
in Russia probe
Attorney General Jeff Sessions told the Senate Judiciary Committee Wednesday that he has not be interviewed by Special Counsel Robert Mueller in relation to the ongoing investigation into Russian interference into last year's presidential election. Sessions hesitated when pressed by Sen. Patrick Leahy, D-Vt., about whether he met with Mueller in relation to the Russia probe, the firing of former FBI Director James Comey, or his own interactions with Russian officials, saying, "Well, I'd be pleased to answer that -- I'm not sure I should without clearing that with the special counsel." ABC
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calls grow to end Russia investigations in Congress this year
A growing number of key Republicans are sending this message to the leaders of the congressional committees investigating potential Trump campaign collusion with the Russians: Wrap it up soon. In the House and Senate, several Republicans who sit on key committees are starting to grumble that the investigations have spanned the better part of the past nine months, contending that the Democratic push to extend the investigation well into next year could amount to a fishing expedition. The concerns are in line with ones raised by President Donald Trump, who has publicly and privately insisted he's the subject of a "witch hunt" on Capitol Hill and by special counsel Robert Mueller. CNN
VOA VIEW: Mueller will try to bleed the taxpayers on nothing.
says he'll push bipartisan health deal; Trump keeps distance
The authors of a bipartisan plan to calm health insurance markets said Wednesday they'll push the proposal forward, even as President Donald Trump's stance ricocheted from supportive to disdainful to arm's-length and the plan's fate teetered. The agreement by Sens. Lamar Alexander, R-Tenn., and Patty Murray, D-Wash., on a two-year extension of the federal subsidies to insurers that Trump has blocked gained an important new foe on Wednesday. The anti-abortion National Right to Life said it opposed the measure because it lacked language barring people from using their federally subsidized coverage to buy policies covering abortion, said Jennifer Popik, the group's top lobbyist. Sun-Sentinel
insurers 'enriched' by Obama health law, as Trump says?
President Donald Trump says health insurers have been "enriched" by President Barack Obama's Affordable Care Act. So why are companies pulling back from the law's insurance marketplaces. Big companies like Aetna and the Blue Cross-Blue Shield insurer Anthem have actually pulled back from many of the law's insurance marketplaces, citing either steep losses or uncertainty over government funding. Sun-Sentinel
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says Comey knew he was going to exonerate Clinton
President Donald Trump took to Twitter on Wednesday to revive his long-standing complaint about the FBI’s handling of the Hillary Clinton email server investigation, alleging that then-Director James Comey had protected the Democratic presidential nominee by prematurely “exonerating” her before the 2016 election. “Comey stated under oath that he didn’t do this — obviously a fix?” Trump wrote. “Where is Justice Dept” Trump’s latest online burst came in response to the FBI’s release of heavily blacked out draft statements from May 2016 by Comey in preparation for closing the Clinton investigation without criminal charges. Seattle Times
Rico leader to seek more relief funds in D.C. trip Thursday
Puerto Rican Gov. Ricardo Rosselló said he plans to push Congress for relief for his debt-ridden, hurricane-ravaged island Thursday, during his first trip to Washington, D.C., since Hurricane Maria. The Puerto Rican leader arrives in Washington one month after the Category 4 storm hit the island, with plenty on his plate. Rosselló said he plans to encourage Congress to pass a nearly $5 billion funding package, a loan President Donald Trump requested for the financially burdened government. The Senate also is considering a $36.5 billion general disaster relief package, passed by the House last week, that includes relief aid for Puerto Rico. The governor said he hopes to persuade federal lawmakers that the island, a U.S. territory, has the ability to manage recovery and rebuilding efforts after Hurricane Maria. If we are not considered in equal terms to Florida, the Virgin Islands, Texas and so forth, Congress will have to deal with a worsened humanitarian crisis, massive exodus from the island, healthcare problems and more," he said. UPI
VOA VIEW: Puerto Rico chose not to be a state - now they want, no, demad, equality.
premier urges Catalan secession leaders to back down
Spain’s prime minister on Wednesday urged Catalonia’s leaders to back down from their bid to gain independence for the region, a day before a central government deadline that could significantly deepen the country’s political crisis. Prime Minister Mariano Rajoy has given Catalan president Carles Puigdemont until Thursday morning to clarify whether he is making the wealthy region independent. The Madrid-based national government is threatening to take the unprecedented step of seizing some or total control of the semi-autonomous region if Puigdemont proceeds with his ambitions of secession. That would likely trigger an explosive reaction in Catalonia. Seattle Times
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verdict in Boston Islamic State beheading plot
A Boston-area man was found guilty on Wednesday of conspiracy to commit acts of international terrorism and supporting Islamic State for a 2015 plot to attack police and behead a conservative blogger who organized a “Draw Mohammed” contest. David Wright, 28, was found guilty of five criminal charges for planning with his uncle and a friend to behead blogger Pamela Geller. The plot fell apart after Wright’s uncle said he wanted to kill law enforcement officers instead and was shot dead by police. Reuters
and NFL at odds on how to get players to stand for anthem
The National Football League rejected U.S. President Donald Trump’s calls to punish players who kneel for the national anthem to protest racism but said on Wednesday players “should” stand and it hopes the demonstrations will stop. NFL Commissioner Roger Goodell made clear he will take a more patient approach than the one urged by the president: Rather than using discipline, the league will continue to nurture players’ efforts to fight racial disparities in the criminal justice system, believing this would make the urge to protest fade. Reuters
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man guilty of immigration fraud in 'Jungle Jabbah' war crimes case
A Delaware County man accused of hiding his past as a murderous Liberian warlord was convicted Wednesday on federal immigration fraud charges in a historic verdict that resonated from Philadelphia’s sizable community of West African expats to the Liberian capital of Monrovia thousands of miles away. Mohammed Jabateh, a 51-year-old father of five and owner of a Philadelphia-based international shipping company, is the first person convicted of crimes stemming from atrocities during the protracted, multi-factioned civil war that ravaged Liberia between 1989 and 1997. Philadelphia Inquirer
of voters think the media concocts fake Trump stories, poll says
A new poll by Politico and Morning Consult shows that 46% of voters believe that major news organizations fabricate stories about the president and his administration. The poll, published Wednesday, also found that 37% of voters think the media doesn't fabricate stories about the president. Another 17% were undecided. Morning Consult conducted the poll between October 12-16 and surveyed 1,991 registered voters. An overwhelming majority of Republicans, 76%, believe the media makes up news about Trump, according to the poll. For Democrats, 65% "think they do not." And yet the poll found that only 28% of voters believe the government should yank the broadcasting license of news organizations, with the majority — 51% — saying it should not be able to do so. USA Today
VOA VIEW: The so-called liberal news fools, 37% must have their head in the sand or no head, or fake news.
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to scrap universal credit helpline charges
People will be able to call the government's universal credit helpline without being charged, within weeks. Prime Minister Theresa May said she had listened to criticism of the charges, which can be up to 55p a minute, and decided it was "right" to drop them. But she again rejected calls by Labour leader Jeremy Corbyn to "pause" the roll-out of the controversial benefit amid fears it is causing hardship. In a symbolic vote, MPs backed a pause after Tory MPs were told to abstain. The opposition won by 299 votes to 0 with one Conservative - Totnes MP Sarah Wollaston - defying her party by siding with Labour. BBC
bans niqab for public services with neutrality law
A Canadian province has passed a controversial religious neutrality law that bars people from wearing face coverings when giving or receiving a public service. Quebec recently expanded the law to include services provided by municipal and public transit services. Women who wear a burqa or a niqab will now have to show their faces while receiving a government service. Quebec's National Assembly passed Bill 62 by a 66-51 vote. The provincial Liberals, who have been in power since 2014, tabled the bill two years ago. Bureaucrats, police officers, teachers, and bus drivers, as well as doctors, midwives, and dentists who work in publicly funded hospitals and health centres, will have to have their face uncovered. Quebec's Bill 62 does not specifically mention the Muslim faith. BBC
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text:
Cray Little, Vero Beach
Letter: Gun rights have come to supersede Americans' rights to life safely
The National Rifle Association and its members ceaselessly assert it's their Constitutional right to own any kind of firearm manufactured regardless of its designed purpose.
Let me ask: Shouldn't it be a citizen's right to live without fear of being murdered by someone with a military assault rifle at school, in a theater, on the street, at work or anywhere else in America?
When I ask my gun-loving friends why they're opposed to an assault-rifle ban, they always trot out the same old canard: If we allow the government to ban one type of firearm, it won't stop there. The government won't be happy until it takes all our guns away.
Hogwash. The NRA has been peddling this tripe for decades, a red-herring argument devised to protect gun manufacturers. NRA members believe the association is standing up for them. Baloney. The NRA's primary objective is protecting the "rights" of the gun industry to produce whatever it desires, even if the product should not be in the hands of nonmilitary personnel.
Why all the paranoia about an assault rifle ban? Here's an idea: Gun owners conflate, and thus confuse, gun ownership with liberty and freedom. They believe, thanks to conservative politicians pandering for their vote, that the United States has been hijacked by a bunch of left-leaning wackos who plan on confiscating their guns and interning all able-bodied white men in Gulag-like encampments where they will be emasculated and forced to watch Chris Matthews on MSNBC.
More folderol to be sure. The Second Amendment will not be overturned. Americans will be able to buy a thousand guns apiece if they wish, and their liberties won't be abrogated by an overzealous group of leftists.
However, when you talk about liberty, think of the 20 little kids slaughtered in Newtown. Now, that's a real loss of liberty.
Need Help? Call us at 1-877-710-6180.
Monday-Friday: 6am-3pm / Saturday: 6:30am-10:30am / Sunday: 7am-11am


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Peanut Butter Crypto Time (DOGE Edition)
A remastered version of the famous dancing banana set "Peanut Butter Crypto Time" by the electronic duo Vogue Machine.
This version has the banana repping Doge and sporting an awesome hat.
- 2160 x 2160 px, Video (37.1 MB)
- This is a signed and limited edition digital creation.
What does this mean?


This All Season Down Alternative King Comforter helps make your bed as comfortable as it can be. Its dual layers make it easy to choose the right weight for any season.
- Features one (1) king comforter and one (1) secondary layer
- King comforter measures 104W x 92L in.
- Secondary layer measures 104W x 72L in.
- Crafted of 100% polyester microfiber with polyester fill
- Sewn-through box quilting design
- Solid white color
- Hypoallergenic, polyester fill
- Additional layer attaches and detaches with five buttons on each side
- Care: Machine wash separately in cold, gentle cycle. Do not bleach. Tumble dry low, remove promptly. Do not iron. If there is no free movement in the washer or dryer, use large capacity commercial washer/dryer.
This item is available at Kirklands.com only, not available in stores. Please note: this item cannot be shipped to APO/FPO addresses.


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Developing Emotional Intelligence in Occupational Therapy Students to Increase Success during Fieldwork Experience and as Practicing Clinicians
What is Emotional Intelligence?
Emotional intelligence is defined as the ability to perceive, understand, use, and manage emotions both within oneself and in interactions with others (Beauvais, Brady, O’Shea, & Quinn Griffin, 2011). Within emotional intelligence, there are soft skills. Soft skills are a set of attitudes and behaviors which not only augment interpersonal interactions but also promote relationship building (Deepa & Seth, 2013; Gonzalez, Abu Kasim, & Naimie, 2013). Soft skills entail intrapersonal and interpersonal qualities which are broadly applicable and include communication, courtesy, flexibility, professionalism, responsibility, positive attitude, integrity, and teamwork abilities (Robles, 2012).
Emotional intelligence can influence one’s ability to work with other health professionals. Soft skills are strategic to effective performance across all job categories. The need for soft skills is especially important within the field of healthcare. Attributes of effective communication, professionalism, courtesy, and teamwork skills are essential in promoting collaboration among health care professionals and in establishing and maintaining the client-health care professional relationship (Reynolds, 2009). (Deptula & Chun, 2013; Gonzalez et al., 2013).
Emotional Intelligence for Health Professionals
Research has shown that a positive interaction between a health professional and client can lead to improved responsibility on the part of the client, for his/her condition (Reynolds, 2009). Deficiencies in skills such as professionalism have been shown to result in adverse effects on patient safety, patient satisfaction, and failure of the patient to adhere to treatment regimes (Deptula & Chun, 2013). On the other hand, skills such as listening and demonstrating empathy have been shown to create a caring environment which builds trust and rapport between the client and health professionals (Beauvais, Brady, O'Shea, & Quinn Griffin, 2011; Gonzalez et al., 2013). The rapport between the health professional and client can greatly assist in the design of interventions and facilitation of client participation within the treatment process.
Emotional intelligence During Clinical Education
Research indicates that occupational therapy students entering their Level I and II fieldwork experiences may lack these sets of skills (James & Musselman, 2006). Brown, Williams and Etherington (2016) found that emotional intelligence factors such as emotional awareness of others, emotional reasoning, and emotional management were significant predictors of occupational therapy student success in fieldwork. Naidoo and Wyk (2016) highlighted students’ concerns in the clinic, particularly the difficulty of establishing professionalism within a supervisor-student relationship, and the need for improved professionalism between clinical educators and students. The lack of these soft skills during fieldwork experience can strain fieldwork students’ professional relationship with their clinical educators (supervisors) and result in fieldwork failure (James & Musselman, 2006). By improving the student- supervisor relationship with learned emotional intelligence skills, students can increase their learning, confidence, and competency as they progress through fieldwork.
Emotional Intelligence Vignettes
The vignettes found on this webpage were designed, developed, and produced following an evidenced-based approach. The scenarios featured in the vignettes were developed with data collected through an extensive literature review and feedback from alumni and clinical educators collected through quality assurance surveys. The curriculum can be used by academic health care programs, students, clinical educators, and clinicians to develop effective emotional intelligence skills.
Please refer to the Manual page for best practices in implementation of Emotional Intelligence education.

domain: literature


text:
Lucy Lavely, Maxey Whitehead and Kelly Campbell in Crimes of the Heart. Photo by Gary Sweetman.
As director Barbara Redmond remarks in her notes for the Banyan Theater Company’s production of Crimes of the Heart, Beth Henley’s three sisters in the play do bear a strong resemblance to another well-known three sisters—the ones of Chekhov’s enduring play. They are, like Chekhov’s women, trapped in a small town with longings to escape, and the specter of suicide does hover over each family. There are other comparisons to make as well, but of course Henley’s Magrath sisters bear more than a few distinctive Southern eccentricities of their own.
Lenny, the eldest (Maxey Whitehead), is turning 30 on the verge of spinsterhood after devoting herself to taking care of her aging grandfather for years. Meg, the middle sister (Kelly Campbell), has gone through more than her fair share of men and booze in her flailing attempts to become a successful singer. And Babe, the youngest (Lucy Lavely), does them one better; she’s just shot her not-nice lawyer-husband in the stomach, which is a reason for the sisters to marshal all their forces to get her off the hook, with the help of a lawyer (Jesse Dornan) who may have his own feelings for the off-kilter but somehow appealing Babe.
It could be the stuff of soap opera, complete with a straitlaced, interfering cousin (Georgia Mallory Guy); Meg’s old boyfriend, now married but still a flame possible to relight (Christopher Swan, who stepped into the role at the last minute but nevertheless manages to inhabit it); threats of blackmail and even a grandpa in a coma. But in Henley’s world of Hazlehurst, Mississippi, the comedy of the piece strikes us as well as its pathos. The atmosphere of the play (which won the Pulitzer back in 1981) moves successfully back and forth between dark and light and many shades in between.
We feel for these sisters, each of whom is a different case of arrested development due to their unhappy family history. The shifting dynamics among the sisters are well-played out here; I especially believed in Whitehead’s Lenny, the dutiful one torn between propriety and loyalty and longing for a beau of her own. But the cast in general brings their characters and their dilemmas to touching life.
Crimes of the Heart
continues through Aug. 26 in the Cook Theatre; for tickets call 351-2808 or go to banyantheatercompany.com


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I liked this sequence of maps
from Audacity showing land use restrictions in England. The website
contains other interesting facts and figures, although I am unconvinced that the solution to our current housing problem lies in forming 250 New Towns. I would rather see the planning system more responsive to price signals, a reform which would tend to favour development near to our (relatively) successful urban areas.

domain: geography


text:
Xu H, He X, Zheng H, Huang LJ, Hou F, Yu Z, de la Cruz MJ, Borkowski B, Zhang X, Chen ZJ, Jiang Q-X. 2014. Structural basis for the prion-like MAVS filaments in antiviral innate immunity. eLife 3:e01489. doi: 10.7554/eLife.01489
Published 25 February 2014
Reviewing editor: Wesley I Sundquist, University of Utah School of Medicine, United States
Mitochondrial antiviral signaling (MAVS) protein forms prion-like aggregates mediated by the N-terminal caspase activation and recruitment domain (CARD) and activates antiviral signaling cascades. Purified MAVS CARD from culture cells self-assembles into filaments. Previously, we reported a low-resolution cryoEM structure of MAVS CARD filament, which exhibits a C3 symmetry with a rotation of −53.6° and an axial rise of 16.8 Å for every unit in the filament (Xu et al., 2014). Recently, a cryoEM reconstruction of MAVS CARD filaments at 3.6 Å resolution was reported with a C1 helical symmetry of a rotation of −101.1° and an axial rise of 5.1 Å per subunit (Wu et al., 2014). The differences in these two models were carefully analyzed recently (Egelman, 2014), which suggested that the helical ambiguity in helical reconstruction was not fully resolved in our previous analysis (Xu et al., 2014). We recently collected a new dataset at higher resolutions. Using a newly developed method for analysis of helical filaments (Clemens et al., 2015), we obtained a 4.2 Å resolution reconstruction of MAVS CARD filaments purified from mammalian cells under native conditions. The new model shows that the MAVS CARD filament exhibits a C1 helical symmetry in agreement with Wu et al. (2014).
CryoEM images of Flag-tagged MAVS CARD (residues 1–100) protein, which was expressed in HEK293T cells and purified as described previously (Xu et al., 2014), were collected using automated data acquisition in a Titan Krios with a Falcon II direct electron detector (Figure 1A; see ‘Materials and methods’ section for detail). Fourier transforms of motion-corrected raw images showed Thon rings up to ∼3 Å (Figure 1B–C). After CTF fitting, the selected raw images were phase-flipped, and individual filaments were selected interactively using EMAN2 Helixboxer (Ludtke et al., 1999). Selected filaments were segmented using individual boxes that had 90% overlap between neighboring ones. Segmented filament images were high-pass filtered at 120 Å to suppress the low-resolution variations in optical density across individual images as well as the contribution of low-resolution noise to particle alignment. The filament datasets were processed using a customized version of Relion 1.2 (Scheres, 2012; Clemens et al., 2015). This ‘helical’ Relion implemented the Iterative Helical Real Space Reconstruction (IHRSR) method (Egelman, 2010) within the framework of Relion 1.2. For 3D classification and auto-refinement, the helical symmetry was refined by the re-implemented IHRSR module hsearch and applied in real space to the 3D volume by the re-implemented IHRSR module himpose. The helically symmetrized volume was masked and used as the reference volume in the next iteration (Clemens et al., 2015).
Particle images were first subjected to reference-free 2D classification and images in good classes showing fine structural details were selected for 3D classification and refinement (Figure 1D). 15,600 out of 27,915 boxed filament segments were used to calculate the final refined map. The summed power spectrum of those filaments showing less than 5° of out-of-plane tilting in the final refinement step (Figure 1E) was calculated and compared with the summed power of the C1 map projections from 360 different directions normal to its helical axis (Figure 1F), and the layerline patterns were similar.
Due to possible symmetry ambiguity, we tested two sets of starting parameters for helical reconstruction (see ‘Materials and methods’ section for detail). Reference models of C1 and C3 symmetries were calculated from our SPIDER-based analysis using sorted fractions of filament particles from the four datasets in our previous paper (Xu et al., 2014). They were filtered to 60 Å and then refined against the new dataset in helical Relion. We found that the new dataset converged better to the C1 symmetry. To reduce model bias, we also calculated a reconstruction by imposing the C1 symmetry for the first five runs of refinement to a C3 model obtained from our original analysis (Xu et al., 2014). The initial C1 symmetry parameters of a twist angle (ΔΦ) = −101.25° and an axial rise (Δz) = 4.75 Å (from our old datasets and adjusted to 4.95 Å due to the change of the imaging system) were derived from the corresponding selection rule defined by indexing the power spectrum. After the fifth run, the refinement was continued to optimize the helical parameters and converged to (ΔΦ = −101.21° and Δz = 5.06 Å) (Figure 2A), close to the C1 symmetry reported by Wu et al. (2014). The final map has an overall resolution of 4.18 Å, estimated from the gold-standard Fourier Shell Correlation (FSC) calculated between two maps that were refined independently against the top and bottom halves of the dataset (Figure 2B; see ‘Materials and methods’ section). To examine the resolution with an independent method, we generated a B-factor weighted map based on the PDB model from Wu et al. (2014) (PDB ID: 3J6J), and used it to calculate FSC against the experimental map. A 0.5 threshold found an estimated resolution of 4.25 Å (Figure 2C), close to the one estimated by using two halves of experimental data (Figure 2B). The new map showed clear grooves in α-helices and multiple bulky side chains (Figure 2D, Video 1).
The crystal structure of MAVS CARD (Potter et al., 2008) was docked into the density by rigid-body fitting. While the six α-helices of the crystal structure of MAVS CARD monomer (PDB: 2VGQ, residues 3–93) fitted into the EM map well, multiple bulky side chains and those residues in the loop between H4 and H5 needed adjustment. The atomic model reported previously (PDB: 3J6J, residues 1–97, Wu et al., 2014) fit into the density well except for some unoccupied densities next to the N- and C-termini of the docked CARD model (Figure 2A,D). These extra densities may be due to the residues from the N-terminal Flag tag and the additional three residues at the C-terminus of the protein used for preparing the cryoEM specimens; these extra residues are not present in the protein sequence shown in the atomic models.
At interface I, the positive and negative charges are distributed at two opposite ends of each CARD subunit, indicating that this interface is mainly mediated by electrostatic interactions (Figure 3B). The positively charged residues R37 and R41 in H3, R64 and R65 in the loop between H4 and H5 from one CARD molecule (grey in Figure 3B) are in close proximity to the negatively charged residues D23 in the loop between H1b and H2 and E26 in H2 of another CARD molecule (cyan in Figure 3B). Compared with the wild-type MAVS, which potently induced IFNβ in a dose-dependent manner, D23A showed significantly decreased activity and mutations of other charged residues (E26, R37, R41, R64 and R65) at the interface to alanine or residues with reversed charge almost completely abolished MAVS activity (Xu et al., 2014).
In the crystal structure of MAVS CARD, the aromatic chain of W56 adopts two alternative conformations, with a major conformer (60% occupancy) exposed to solvent and stacked against the ring structure of residue F16 in immediate vicinity (Potter et al., 2008). In the cryoEM map, the density of one conformer is resolved (Figures 2D, 3D) and there appears density corresponding to the side chain of R43 from an adjacent CARD (Figure 3D), suggesting a possible cation–pi interaction between these two residues, as reported previously (Wu et al., 2014). Alanine substitution of R43 almost completely abolished MAVS activity (Xu et al., 2014). Besides W56, the ring structures of residues F16 and Y30 also appear to be important for filament assembly. Single alanine substitution of F16, W56 or Y30 almost completely abolished MAVS activity, while substitutions with different ring-containing residues to these positions, such as F16H, W56F, W56Y, Y30F and Y30H, were able to largely retain MAVS activity (Xu et al., 2014). Another residue involved in stabilizing the interface is R52, whose replacement by alanine significantly decreased its activity (Xu et al., 2014).
Interface III mediates the interactions between adjacent monomers along the helical trajectory. Close to the central pore of the helical filament, residue L48 from each MAVS CARD monomer contributes to the formation of a hydrophobic core with G50 and A44 in close proximity (Figure 3A, top view and Figure 3E). Substitution of L48 with charged residues (D or K), but not alanine, completely abolished MAVS activity in HEK293T cells (Xu et al., 2014). It is interesting to note that L48 is not conserved, and is R or Q in MAVS from multiple other species. The filaments might need to rearrange in order to accommodate such substitutions. The small side chain or hydrophobicity of A44 may be important for the packing at this hydrophobic interface because its mutation to T impaired MAVS CARD filament formation in vitro (Xu et al., 2014). Charged residues R37, R41, D40 and D53 are located at the outer rim of the filament forming electrostatic interactions together with charged residues at type I interface. Single alanine substitution of these residues almost completely abolished MAVS activity (Xu et al., 2014).
Overall, the loss-of-function mutation data are consistent with both the C1 map reported here and the C3 map obtained previously (Xu et al., 2014). However, although key residues involved in the interactions are almost identical in the two models, the detailed interactions at the interfaces are different according to the two maps, indicating that mutagenesis analyses alone cannot distinguish one model from the other.
MAVS CARD filaments from our new dataset converged to almost the same C1 symmetry as reported by Wu et al. (2014), not the C3 symmetry as we reported previously (Xu et al., 2014). The heterogeneity of the samples and the limited resolution of images were likely among the factors that led to the exclusion of the C1 model in the original analysis. We wish to correct this mistake and apologize for any confusion it might have caused. We stand by all other data in the paper, including in vitro mapping of the oligomerization interface, cell-based mutational analyses, super-resolution SIM imaging of MAVS aggregates in virus-infected cells, and the crystal structures. These experiments for the first time identified most of the key residues involved in MAVS polymerization, leading to an extensive mapping of the molecular surfaces for forming the MAVS filament.
Flag-MAVS CARD (1–100) expressed in HEK293T cells was purified in a buffer containing 50 mM NaCl. Freshly purified protein was processed for EM experiments to minimize bending and overlapping of filaments on cryoEM grids. To prepare cryo-EM specimens, 2.5 μl freshly purified MAVS CARD (0.1 mg/ml) filaments in suspension were applied to a glow-discharged Quantifoil R2/2 holey carbon grid (Quantifoil Micro Tools GmbH, Jena, Germany) coated with a thin carbon film and plunge-frozen inside a Vitrobot (FEI, Hillsboro, OR).
Movie data were collected in a FEI Titan Krios microscope equipped with a Falcon II detector at the HHMI Janelia Farm Research Campus. The microscope was equipped with a Cs corrector (Cs = 0.01 mm) and operated at 300 kV. EPU (FEI) was run to control automatic data collection across multiple preselected holes in the holey grids. Images were taken using a defocus range of −2.5 to −4.0 microns at a nominal magnification of 59,000×, which corresponds to a calibrated pixel size of 1.05 Å at the specimen level. Images were taken with a total dose of 35 e−/Å2 distributed over 16 frames. The movie data were processed using the program dosefgpu_driftcorr (Li et al., 2013). Frames 3–12 of every movie were summed together as the corrected image (Figure 1A). The carbon-support of our filaments made the motion between consecutive frames very small (mostly less than 2 pixels) and we therefore did not do motion correction for individual filaments (polishing) in Relion. We started with 27,916 filaments. After 2D classification, 15,600 filaments were selected. During the 3D classification into two different classes, there was a negligible fraction of the filaments conforming to a different volume with poor alignment statistics. We therefore kept all 15,600 filaments for final map calculation, which correspond to ∼80,000 images of individual CARD units.
In order to calculate a gold-standard FSC from truly independent datasets, we divided the 15,600 filaments into the top and bottom two halves. These two datasets had negligible overlap. Two separate C1 models were generated using the SPIDER-based method from a small sorted fraction (∼13%) of filaments out of our old datasets as described before (Xu et al., 2014), and imposed with diagonally varied symmetry parameters (5.22 Å, −102.2°) and (4.82 Å, −100.2°), respectively. These two models were used as initial models and separately refined against the two half datasets in helical Relion. The two refinements converged to almost the same symmetry parameters, (5.05 Å, −101.25°) and (5.08 Å, −101.20°), respectively. The two volumes were post-processed in EMAN2 and aligned in CHIMERA. The map calculated from the top half of the dataset was rotated −2.4° and shifted by −1.05 pixels before being compared with the one from the bottom half to calculate a gold-standard FSC using e2proc3d.py in EMAN2. The calculations in the final refinement steps were done in the largemem nodes of the STAMPEDE supercomputer at the Texas Advanced Computer Center (TACC) in Austin, Texas. Molecular modeling was done in CHIMERA and Coot (Emsley et al., 2010).
|National Institutes of Health||R01GM088745||Hui Xu, Brian Borkowski, Qiu-Xing Jiang|
|National Institutes of Health||R01GM093271||Hui Xu, Brian Borkowski, Qiu-Xing Jiang|
|National Institutes of Health||R01GM088197||Xiaojing He, Xuewu Zhang|
|National Institutes of Health||1S10RR027972||Qiu-Xing Jiang|
|American Heart Association||12IRG9400019||Qiu-Xing Jiang|
|Welch||I-1684, I-1389, and I-1702||Hui Zheng, Qiu-Xing Jiang, Hui Xu, Zhijian J Chen, Xuewu Zhang|
|Cancer Prevention Research Institute of Texas||RP120474||Hui Xu, Qiu-Xing Jiang|
|National Institutes of Health||R01AI093967||Zhijian J Chen|
|Howard Hughes Medical Institute||Zhiheng Yu, Michael Jason de la Cruz, Zhijian J Chen|
|National Institutes of Health||C06RR30414||Hui Xu, Hui Zheng, Lily J Huang, Brian Borkowski, Qiu-Xing Jiang|
EMAN: semiautomated software for high- resolution single-particle reconstructionsJournal of Structural Biology 128:82–97.https://doi.org/10.1006/jsbi.1999.4174
RELION: implementation of a Bayesian approach to cryo-EM structure determinationJournal of Structural Biology 180:519–530.https://doi.org/10.1016/j.jsb.2012.09.006
We are grateful to Dr Edward H Egelman for pointing out the ambiguity in helical reconstructions. We are indebted to Dr Z Hong Zhou, Dr Peng Ge and Mr Ke Ding at UCLA for sharing the helical Relion with us and for teaching us in using the software to perform helical reconstruction. We thank Mr Mohammed Sayed in the Jiang lab for his help in selecting the filaments out of EM images. Q-XJ is indebted to Dr Hernando Sosa (Albert Einstein) for discussions of and help in Fourier-Bessel indexing of the power spectra, and to Drs David DeRosier (Brandeis University), Fred Sigworth (Yale University) and Anthony Crowther (MRC LMB) for their comments and suggestions on the parallel sorting of the datasets against different models.
- Version of Record published: August 28, 2015 (version 1)
© 2015, Xu et al.
This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.


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News reaching Adeoliseh Blog recently stated that Bobrisky bashed Big Brother Naija Lockdown season 5 reality show housemate, Vee.
Following the reports, it was obtained that Vee revealed the love she has for Bobsrisky to a social media user, added that Bobrisky’s advise works for herself and not for everyone.
Child of Grace to Vee; So, I shouldn’t take Bobrisky’s advice?
Vee to Child of Grace; I love Bobrisky but her advice is kind of personal to herself. Its works for her, might not work for you. Hustle the way you know how to.
In response to the chat, Bobrisky did a video called Vee out as she said that good girl doesn’t pay.
“Good girl no dey pay oooo, the good girl you did in 2020, what’s the gain?
“Let the money spender spend money on you”, she submitted.
However, in the comment section, thousands hailed Vee with the say that she said the truth and they love her for that.
Toeing in same line, one of the comments revealed that who Bobrisky meant as good girls are runs girls.

domain: celebrity


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I know it has been quite some time since you last heard from the EmpowerMoments team. It has been over 10 months to be exact! The last time I wrote to you I encouraged you (and me) not to get weary in well doing. For in due season we would reap if we chose not to faint. Today I am happy to report that I am finally reaping the fruits of my labor!
EmpowerMoments for the Everyday Mom: A 31-Day Devotional to Empower Your Motherhood is now available for purchase. This devotional is full of the same raw and real testimony that you grew to love from the EmpowerMoments team. I encourage you to grab a copy for yourself or for a gift to anyone who will benefit from this book. It will make a great baby shower gift for a mother-to-be or a birthday gift for a more seasoned mother.
Honestly, what makes this book so special is that I have shared many of my motherhood struggles with you for the sole purpose of empowering and catapulting you into another dimension of your own motherhood.
Won’t you come join me on this journey to becoming the mother that God created you to be?
I have so many exciting things coming up and I don’t want you to miss anything. So please sign up for my updates at http://kristenrharris.net. You will also receive my free ebook, Why Am I Here: 5 Steps to Finding Your Purpose.
I EMPOWER you to grow into everything that God created you to be! Go be great!
Mrs. Kristen Harris is a wife, mother, entrepreneur and dedicated servant. She is extremely passionate about women’s spiritual advancement, hence the founding of EmpowerMoments. She is the CEO of Pizzazzed Plus, a sweet treats boutique. As an avid reader, Kristen enjoys reading the Bible and other non-fiction pieces. Her driving inspiration is when God says to her: “For I know the plans I have for you, plans to prosper you and not to harm you, plans to give you hope and a future.” (Jeremiah 29:11) Shecurrently resides outside of Chicago, Illinois with her wonderful husband and three lovely daughters where she is an active member of New Life Covenant Church.


If you're a parent, chances are Elf on the Shelf is as unavoidable in December as Christmas music. The toy, meant to remind children that Santa's watching, is said to report to the North Pole each night and return to a new spot in the morning. While the elf could easily just relocate from the mantel to a bookshelf to a countertop, some people go all out—and one of those people is Busy Philipps.
Busy—mom of two and known for her roles on Dawson's Creek, Freaks & Geeks, and most recently, Vice Principals—shares her elaborate Elf on the Shelf scenes on her Instagram account. The elves have participated in five years of elf races, flown planes, set up a farmers market, and even done their own laundry. When the family was recently in New York City, the elves packed up (literally!) and came with, even having a bit of touristy fun themselves.
The rise of Instagram has upped the ante for Elf on the Shelf parents, with one nurse mom even taking an elf to a real hospital (during a slow period) after an unfortunate incident with the family dog.
While Elf on the Shelf has been around for 12 years now, selling over 11 million elves, it's not the first elf on the block. Dabney wrote about her family's knee-hugger elf tradition, which she recalls as a December version of an Easter egg hunt.
Enjoy a few more of Busy's creative elves, and maybe get some inspiration for your own.


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Looking for stylish indoor firewood storage ideas? Check out my top 10 creative storage solutions for any indoor space.
Upgrade your space in just a few minutes, with this quick and inexpensive project. Learn how to paint the inside of a fireplace, for cheap!
Making polymer clay earrings is one of my favorite creative outlets. Not only are polymer clay earrings fun and trendy, but they are lightweight and relatively inexpensive. Most of all, I enjoy the endless creative possibilities! With Christmas coming quickly, I starting thinking of personal gifts I can make. It didn’t take long for me
If you’re a pet owner, you understand that accidents happen. When we bought the farmhouse, we noticed some dark discoloration on some of the hardwood floors. I decided to put some of the most commonly recommended methods to remove stains from wood floors to the test. Follow along with my little experiment to and learn
When I first moved, one of the first things I needed to purchase was a large sofa for the main living space. SOURCE If you’ve been here before, you’re aware of my love for light and airy living spaces. I’m a neutral lover, decorating with tans, khaki’s and whites since… forever! Wanna know what’s really
As the warm weather moves in, so do the bugs. If you own livestock or spend time outside, you know how irritating these little pests can be to animals and humans alike. While fly spray or can be helpful, these topicals can come with a hefty price tag and a long list of toxic chemicals.
Did you know a group of goats is called a trip? Me either… but you know what – my new goats are a trip! Mom has always wanted goats – since forever. When we moved to the farm, one of the first things I worked on was finding goats that would make a great addition
Ever wanted to learn how to paint wood floors? Here’s how I transformed my master bedroom floors in less than a day.
Since I was a little girl, I’ve always dreamed of living on a farm. I have had horses most my life, and the goal was always to get to a place where I could move them home. Living on a farm was the ultimate “I’ve made it” goal. I swear I come by the farmhouse
Semi-hydroponics – or “semi-hydro” – is growing plants without the use of organic soil medium. Typically, LECA (lightweight expandable clay aggregate) is the preferred growing medium for this type of setup. It is rather easy to convert plants to LECA or a semi-hydroponic system, and many plants tolerate the conversion surprisingly well. I actually started

domain: design


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National Central Cooling Company wins renewal of master services agreement with the military
Dubai-listed National Central Cooling Company (Tabreed) on Tuesday said it had won a AED6 billion ($1.63 billion) contract from the UAE armed forces to supply cooling services for 20 years.
The news boosted Tabreed's share price, which was 9.9 percent higher at 0630 GMT.
The new contract is a renewal of the master services agreement with the military, Tabreed said in a statement.
Tabreed's first district cooling plant was commissioned by the UAE armed forces in 1998 to service their facilities in Abu Dhabi.For all the latest energy and oil news from the UAE and Gulf countries, follow us on Twitter and Linkedin, like us on Facebook and subscribe to our YouTube page, which is updated daily.


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Presente is a bilingual publication focused on Western PA’s growing Latinx community. We are the voice of Pittsburgh and Western PA’s Latinx community! Our mission is to share culturally relevant content that keeps our Latino population connected, empowers our community, and elevates the quality of life of Hispanics in the region. Our goals are to:
PRESENTE was founded in 2019 by María Manautou Matos, a Puerto Rico native living in the Pittsburgh region for over 20 years. A student board member of Carnegie Mellon University’s Spanish and Latin Student Association, María passionately took on every opportunity to represent and highlight Latino cultures. Under her leadership, CMU held its first Latin America Food Festival to great acclaim.
Years passed. As a Hispanic professional, then a wife and mother, María found it challenging to stay connected to her roots and fellow Hispanics in the region. The population had grown exponentially, Latino leaders were making an impact, organizations were holding vibrant events and yet the news was net getting around. Keeping up with information scattered across multiple Facebook groups was tedious. Hispanics represent 19.5% of the U.S. population and are the second fastest growing-population segment since 2000. Regionally, Latinos are relocating to Western Pennsylvania at double the national rate.
There had to be a better way; Western PA Hispanics deserved it… And, that is when the idea for PRESENTE was born!
PRESENTE is the award recipient of the COVID-19 Local News Relief Grant Fund by:
PRESENTE is a proud member / partner of:
María Manautou-Matos holds a bachelor’s degree from Carnegie Mellon University and a master’s degree from Duquesne University. She has worked in marketing communications and multimedia for over 15 years, most recently serving as Marketing Director for Brightside Academy. María partners with the Pittsburgh Hispanic Development Corporation, the Pittsburgh Metropolitan Area Hispanic Chamber of Commerce, and other organizations serving the local Latino community. As a licensed Bilingual Associate Agent with the Daniel Carinci Agency, María proudly serves Spanish-language insurance assistance, a much needed resource for the local Hispanic population.
For additional information or collaboration inquiries contact, LatinoNews@PresentePgh.com.
PRESENTE Pittsburgh Latino Magazine is part of PRESENTE Pittsburgh Media LLC.
Pittsburgh’s Hispanic community is the population segment experiencing the largest growth in the region. Our online magazine was created to connect, celebrate, and empower Pittsburgh Latinos. Our bilingual format is inclusive of 2nd to 4th generation Hispanics looking to connect with their roots and contribute to our growing community. Pittsburgh Latino Magazine is published by Presente Pittsburgh Media.


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Aussie film duo Maria Tran and Takashi Hara are now days away from premiering the official trailer for their feature debut, Echo 8. The two jointly direct the pic as well as star in the film, which could arrive to audiences commercially as early as 2023.
A highly trained assassin flashes between a nightmarish dream and her reality at a secret underground organization. When her latest mission involves killing a grieving mother, she realizes her target is closer to home than she realizes—much closer.
It’s actually been almost three years since the start of production on Echo 8, hampered by some of the typical challenges of independent film – augmented by the severity of the Covid-19 no less. Production completed last February while Tran and Hara moved onto other work while plotting post production, with Tran herself having since taken up casting for upcoming Paramount+ Australia crime series, The Last King Of The Cross.
Echo 8 was penned by Elizabeth H. Vu and also stars Gabrielle Chan, David Vuong, Mike Leeder, Michael Quan, Eliza Nguyen, Fellino Dellosa, Joe June and Damien Sato. The film is produced by Vu and Hara, and is exec produced by Tran.
The official trailer for Echo 8 will go live on Friday, August 19, with the production inviting hopefuls to join the Facebook group for the timed event.


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The National Treasury Confirms Plan To Pass Sh 9 Trillion Debt Ceiling
By Asuma | self meida writer
Published 13 days ago - 0 views
Our country was greatly affected by the covid 19 pandemic. When it was being confirmed in our country, its rules were hard to follow what made the government to close quite a number of revenue sources. Great businesses were forced to be closed since the virus rules were hard to follow.
Kenya is a developing country and it is unstable. Therefore, the government was forced to go for loans from other financial institutions to support it's people.Currently, our country is battling a big debt which it is required to settle. Still the government requires some money that will enable it run its projects.
Following the current report released from the government, the Kenyan treasury confirms plan to pass 9 trillion debt. The money will help in running the government projects within the year.
The fact being that the government is lacking money and is having big debts, it is likely to chop off some amount from civil servants and Teachers, which may result to great trouble as most of the civil servants are lowly paid. This will help in running the government plans.
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Born in Tbilisi, Georgia |
Nino lived in Georgia until she was twelve and then, because her father was a Georgian diplomat, the family travelled for several years throughout Eastern Europe. In 2009 she came to the University of Toronto to continue her education, studying Cultural Studies, Politics and Policy. Nino is and has always been fascinated by the concept of identity, specifically national and diasporic identities, and thought Toronto would be a great place to research this. Toronto’s diversity is something she cherishes and she is impressed by how its growth in population runs parallel to its growth in diversity. Nino feels as if she learns something new about Toronto on a daily basis. She also speaks five languages, and thinks that here; it just might be possible to practice them all in one day!
Toronto as Home
When Nino first moved to Toronto, she stumbled, by accident upon this beautiful place. Alexandra Gates, right in between the Royal Ontario Museum and the Koerner Hall, is a peaceful and magical area. Here, even though one is in the middle of a busy downtown area, one can see incredibly beautiful scenery. Even though Nino has now been in the city for half of a decade she still finds the time to wander here.
Connection with the Past
Over ten years ago, Nino and her mother found this vintage ring, made of gold, silver and unpolished diamonds, at the Tbilisi Jewellery Flea Market in Georgia. This gift from her mother reminds Nino of a “flower smiling to the sun” and wearing it makes her feel close to her mom. It also triggers memories of her grandmother who was also fond of the ring and of Georgia because this ring is ‘cultural’. Long ago women of noble descent wore a headpiece called Tchikhtikopi which was a headband with a white veil. An essential part of the head piece was the diamond pin that held it together and this ring is actually made from one of these pins. For this reason, every day that she wears it, she feels as if she is wearing a part of her cultural heritage.