text:
Your safety is our top priority
Hotels in Zichyújfalu
Why book with Hotels.com?
Where to stay in Zichyújfalu?
- Novotel Szekesfehervar
13.4 miles to city centreGuest rating8.6.Fabulous41 Hotels.com guest reviews
- Best Western Plus Lakeside Hotel
Best Western Plus Lakeside Hotel4-star
13.7 miles to city centreGuest rating9.0.Superb25 Hotels.com guest reviews
- Szent Gellért Hotel
Szent Gellért Hotel3-star
13.2 miles to city centreGuest rating9.2.Superb15 Hotels.com guest reviews
- Hotel Szárcsa
12.4 miles to city centreGuest rating8.6.Fabulous27 Hotels.com guest reviews
- Hotel Vadászkürt Superior
Hotel Vadászkürt Superior2-star
13 miles to city centreGuest rating9.0.Superb4 Hotels.com guest reviews
12.6 miles to city centreGuest rating8.0.Very Good11 Hotels.com guest reviews
- Session Hotel Ráckeve
Session Hotel Ráckeve3.5-star
13 miles to city centre
- Ludwig Hotel
13.7 miles to city centreGuest rating9.6.Exceptional4 Hotels.com guest reviews
- Smart Rooms
12.5 miles to city centreGuest rating8.6.Fabulous4 Hotels.com guest reviews
- Öregszőlő Vendéház
11.5 miles to city centre
- Amazing Home in Lovasberény w/ Wifi and 1 Bedrooms
Amazing Home in Lovasberény w/ Wifi and 1 Bedrooms3-star
12.4 miles to city centre
- Károlyi Kastély Hotel & Restaurant
Károlyi Kastély Hotel & Restaurant3.5-star
22.1 miles to city centreGuest rating9.0.Superb15 Hotels.com guest reviews
- Apartman Daniel
22.6 miles to city centre
Find out more about Zichyújfalu
Our 3 most booked Zichyújfalu hotels from the last hour are:
1. Awesome Home in Sukoró w/ Wifi and 1 Bedrooms
But low prices and a great selection are not the only thing Hotels.com offers. We also have numerous guest reviews for Zichyújfalu, so you can get a better idea of where you're staying and what you should expect.
Why use Hotels.com to book your Zichyújfalu accommodation?
We can help you to find the perfect Zichyújfalu hotel room for almost any occasion. With our fast and secure hotel search you can easily compare different Zichyújfalu hotels by:
- - Price
- - Availability
- - Zichyújfalu neighbourhoods
- - Nearby Zichyújfalu attractions and landmarks
- - Genuine Hotels.com guest reviews for Zichyújfalu
- - Star rating
- - Amenities
- - Hotel name & chain
- - Theme
Alternatively, you can use our detailed Zichyújfalu maps showing hotel locations in Zichyújfalu, using all the filters listed above.
Cheap Zichyújfalu hotels - getting the best deal
On Hotels.com you can always be sure you're getting the best deal.
We make it easy to save money on every booking. We offer our Price Guarantee on most bookings. Plus we offer 2 more ways to save:
1. Hotels.com Rewards - Collect 10 nights, get 1 free*
2. Hotels.com Deals & Discounts - Search over 10,000 deals!
Not found the right property yet? Explore other destinations or refine your current search further.


text:
A teaser website for a new SEGA game has popped up at the address coj.sega.jp. Only a title, Code of Joker, and a date of February 1st are given. Given the card based title, the game could be a new card based arcade game. In mid-February, SEGA will have the biggest booth at the Japan Amusement Expo, so this could very well be an arcade game that will debut at the show. Another possibility is that it is a console, handheld, or mobile title. But given the timing, and name, arcade is the strongest possibility.
Special thanks to SEGAbits forum member Aki-at for the news tip!Ad:
3 responses to “SEGA of Japan teases new game entitled “Code of Joker””
Yup. That’s a game or something alright.
Somebody take the “Code of Princess” cover and attach the Joker’s face to it. XD
I’m gonna go out on a limb and say it’s an iOS Collectible Card Game. Those take up like 90% of the “top grossing apps” on Android, and I’m assuming it’s a similar situation on iOS.
It’s managed to get my attention based off of how colorful and intriguing that piece of art is. I’ll keep an eye out. As I don’t have a device for iOS gaming, I’m hoping for a console or handheld type product here.

domain: game


text:
There’s something for every child at the library!
Hear good stories and more:
Babies 0-18 months — Share boardbooks with your
caregivers, visit, and play at Lapsit Storytime! (Registration required)
Todders ages 18-36 months —
Listen, laugh, sing, and shake your sillies out in 20 minutes of action-packed
ages 3-6 years — share 30 minutes of stories, songs, and rhymes at Family
- Elementary school aged children:
Read to a Dog in our Tails for Reading program!
Want to find more fun at the library? Check out our full
calendar of events.
Important Note: Carver County
Library is not responsible for the content or accuracy of the information
provided on external websites. The inclusion of a link does not constitute
an endorsement by the library of that website.

domain: library


text:
Researchers have created atomically thin artificial neurons capable of processing both light and electric signals for computing. The material enables the simultaneous existence of separate feedforward and feedback paths within a neural network, boosting the ability to solve complex problems.
For decades, scientists have been investigating how to recreate the versatile computational capabilities of biological neurons to develop faster and more energy-efficient machine learning systems. One promising approach involves the use of memristors: electronic components capable of storing a value by modifying their conductance and then utilising that value for in-memory processing.
However, a key challenge to replicating the complex processes of biological neurons and brains using memristors has been the difficulty in integrating both feedforward and feedback neuronal signals. These mechanisms underpin our cognitive ability to learn complex tasks, using rewards and errors.
A team of researchers at the University of Oxford, IBM Research Europe, and the University of Texas, have announced an important feat: the development of atomically thin artificial neurons created by stacking two-dimensional (2D) materials. The results have been published in Nature Nanotechnology.
In the study, the researchers expanded the functionality of the electronic memristors by making them responsive to optical as well as electrical signals. This enabled the simultaneous existence of separate feedforward and feedback paths within the network. The advancement allowed the team to create winner-take-all neural networks: computational learning programs with the potential for solving complex problems in machine learning, such as unsupervised learning in clustering and combinatorial optimization problems.
2D materials are made up of just a few layers of atoms, and this fine scale gives them various exotic properties, which can be fine-tuned depending on how the materials are layered. In this study, the researchers used a stack of three 2D materials – graphene, molybdenum disulfide and tungsten disulfide- to create a device that shows a change in its conductance depending on the power and duration of light/electricity that is shone on it.
Unlike digital storage devices, these devices are analog and operate similarly to the synapses and neurons in our biological brain. The analog feature allows for computations, where a sequence of electrical or optical signals sent to the device produces gradual changes in the amount of stored electronic charge. This process forms the basis for threshold modes for neuronal computations, analogous to the way our brain processes a combination of excitatory and inhibitory signals.
Lead author Dr Ghazi Sarwat Syed, a Research Staff Member at IBM Research Europe Switzerland, said: ‘This is a highly exciting development. Our study has introduced a novel concept that surpasses the fixed feedforward operation typically utilised in current artificial neural networks. Besides the potential applications in AI hardware, these current proof-of-principle results demonstrate an important scientific advancement in the wider fields of neuromorphic engineering and algorithms, enabling us to better emulate and comprehend the brain.’
Dr Syed and Dr Yingqiu Zhou (who were DPhil students and lab colleagues at Oxford) conducted the experimental work. According to Dr Zhou, now a Postdoctoral researcher at Denmark Technical University, their implementation captures the essential components of a biological neuron through the optoelectronic physics of low-dimensional systems.
They note that we have created atomically abrupt semiconductor junctions through the design of our heterostructure stack. The stack, specifically delivers a heterojunction that acts as the neuronal membrane, while the graphene electrodes that contact the heterojunction serve as the neuronal soma. This way the neuronal state is represented in the soma, but modified by the changes in the membrane, just like in actual neurons.
As the advancement of artificial intelligence applications has grown exponentially, the computational power required has outpaced the development of new hardware based on traditional processors. There is an urgent need to research new techniques, including the work of co-lead author Professor Harish Bhaskaran at the Advanced Nanoscale Engineering Laboratory, University of Oxford, and at IBM Research Zurich laboratory.
Professor Bhaskaran said: ‘This entire field is super-exciting, as materials innovations, device innovations, and novel insights into how they can be creatively applied all need to come together. This work represents a new toolkit, exploring the power of 2D materials, not in transistors, but for novel computing paradigms.’
Co-author Professor Jamie Warner, University of Texas at Austin, said: ‘The use of such 2D structures in computing has been spoken about for years, but only now are we finally seeing the payoff after spending over seven years in development. By assembling wafer-scale 2D monolayers into complex ultrathin optoelectronic devices, this will enable the start of new information processing approaches using 2D materials based on industrially scalable fabrication methods.’
Our findings are more of exploratory nature than actual demonstrations at the system level, Dr. Syed says. Although we aim to expand on this concept in the future, we are convinced that our current proof-of-principle results demonstrate an important scientific interest in the wider fields of neuromorphic engineering, enabling us to better emulate and comprehend the brain. Professor Bhaskaran points out that exciting research developments are important for future innovation, but this is not technology that one should expect in their mobile phones in the next two years.
The Latest Updates from Bing News
Go deeper with Bing News on:
Atomically thin artificial neurons
- Artificial Intelligence
By Joe Rennison China’s tech firms were caught off guard by breakthroughs in generative artificial intelligence. Beijing’s regulations and a sagging economy aren’t helping. By Paul Mozur ...
- Measuring exciton 'holes': Insights into charge transfer at atomically thin interfaces between semiconductors
In the current study, the researchers used a structure consisting of two different atomically thin semiconductors to show that the hole of the exciton transfers from one semiconductor layer to the ...
- Scientists find new way to roll atomically thin nanosheets into scrolls
Tokyo, Japan – Researchers from Tokyo Metropolitan University have come up with a new way of rolling atomically thin sheets of atoms into “nanoscrolls.” Their unique approach uses transition ...
- Evidence that atomically thin hafnium telluride is an excitonic insulator
The recent findings gathered by Peng and his researchers suggest that atomically thin HfTe 2 could be the first known excitonic insulator in a natural solid with a purely electronic transition origin.
- 2D single-crystalline LiCoO₂ nanosheets developed for high-performance battery-supercapacitor hybrid devices
A team led by Prof. Wu Zhongshuai has developed novel 2D atomically thin (001)-oriented single-crystalline LiCoO 2 nanosheets with longer Li + intercalation distance and (001) planes dominated ...
Go deeper with Bing News on:
- Automotive Engine Oil Market Size to be Worth USD 64.8 billion by 2031, Growing 1.9% CAGR: Insights from Transparency Market Research, Inc.
The development of nano-engineered lubricants incorporating nanoparticles ... Royal Dutch Shell plc Pentagon Lubricants Private Limited Leo Lubricants Pvt. Ltd. DANA LUBRICANTS FACTORY LLC Castrol ...
- Calcutta HC Judge Recuses From Tata Singur Case
Justice Mousumi Bhattacharya of the Calcutta High Court has recused from hearing the case on West Bengal Industrial Developmen ...
- Nano Silica Market - Know The Untapped Revenue Growth Opportunities
Nano Silica Market Trends The drivers propelling market growth include the increasing adoption of nano silica across diverse applications ...
- The luxury wool that’s finer than silk
W hen Pier Luigi Loro Piana was attending wool auctions in Australia during the Seventies and Eighties, the finest merino fibres clocked in at 16 microns, a nano-measurement used ...
- The Cheapest Car in the World Was Supposed to Run on Compressed Air
Yet, around the same time, Tata Motors was struggling mightily with the production of any kind of Nano at all. In 2006, the automaker announced that it would build a new factory in West Bengal ...

domain: news


Trusted by 50k+ aspirants
UPSC Focus Magazine (RAU’S IAS)- November 2019
60 in stock
Black & White Printout
There are no reviews yet.
You must be logged in to post a review.
Lukmaan IAS Public Administration Optional Handwritten Classnotes
Ethics GS Paper 4 Handwritten Classnotes – 2016
Synergy Public Administration Optional Study Material
Location Factors Study Material – 2016


text:
Dog Grooming Classes
As an ABC Certified Pet Groomer, you will have the opportunity to build long-lasting relationships with clients and their pets. A professional dog grooming career affords animal enthusiasts a creative and artistic profession that is also fulfilling as it contributes to the overall health and well-being of a variety of animals. The dog groomer’s responsibilities include bathing, brushing, clipping, and manicuring pets on a regular basis. As a professional pet/dog groomer, you will be asked to recommend different products to pet parents that will help to enrich the pet’s look, health, and quality of life.
The ABC Professional Certified Pet Groomer can work in a grooming salon, mobile grooming enterprise, animal shelter, veterinary office, or even start their own dog grooming business. In addition, because dog grooming professionals spend a great amount of time handling pets and inspecting them closely, they are most likely to detect physical conditions that owners may not otherwise notice. Properly checking the animal’s ears, teeth, eyes, coat, and overall condition is vital to providing clients with excellent grooming services and contributes greatly to the preventative health care of each pet.

domain: pet


As the Senate today, Wednesday, commenced debate on the present economic quagmire facing he country
The debate and contributions by various Senators is at the moment on- going.
In their contributions, Deputy Senate President Ike Ekweremadu and Senator Dino Melaye, All Progressives Congress, APC, Kogi West called on President Muhammadu Buhari to Rejig his cabinet by either sacking incompetent ministers or reshuffling some by changing them to other ministries where they could perform better.
Also Senator Anyanwu said that President Muhammadu Buhari’s body language to business concerns and businessmen must change to the positive.
Below are some tweets from the Senate’s twitter handle


text:
1 March 2012 Jolly Harbour to Charlestown, Nevis
The alarm went off at six o’clock; we had a quick breakfast, checked the engine again, made sure that everything was secure and left at half past six. On the way out, I put up the main sail with 1½ reefs, expecting 20-25 knots winds. For the first hour, we had very light winds – less than 15 knots, so we continued to motor. Thankfully the wind picked up to the forecast strength as we moved away from the island.
The wind was more or less directly behind us, so I rigged up our spinnaker pole to starboard, rolled out the genoa and let the main out to port with a preventer. We rocked and rolled downwind in the 2-3 metre waves.
Unfortunately the wind direction wasn’t very consistent and kept changing direction by 30 degrees as cloud systems passed overhead. This meant that we couldn’t relax and we had to gybe the mainsail six or seven times in the eight hour trip. At one point, we had an unintentional gybe which was fortunately slowed down by the preventer.
I hooked a very nice big Dorado, which I fought for ten minutes. I managed to get it alongside and had just started to pull it in with my hands when it gave a final big thrash and broke lose – gutted…
The anchorage in Charlestown is now covered with moorings, which are compulsory. These moorings are a long way from the beach, so it feels a bit like we are in a car park. Fifteen years ago, there were hundreds of coconut palm trees stretching as far as the eye could see, but now there are only a few spread about because most have died from some virus. However, it is still a nice place to be, with the volcanic mountain stretching upwards ahead of us.
2 March 2012 Charlestown, Nevis
We were woken up at half past twelve by outrageously loud music coming from beach bar directly opposite where we’re moored – the locals obviously can’t buy speakers any smaller than a wardrobe. We had to close our hatches and turn on our fans to try to get back to sleep.
Bleary-eyed the next morning, we went into town to clear in. It wasn’t too painful until we got to the Port Authority and had to pay £40.00 for various port fees. We walked to the tourist office, picked up some maps & brochures and booked a horse ride for tomorrow morning.
The anchorage is very rolly, so we motored along the coast to see if we could find somewhere closer to the riding stables. We found that the moorings further up the coast are even more exposed, so we picked one up for lunch in Tamarind Bay and went snorkelling on Cades Point which was rubbish.
We sailed back to Charlestown and, in a startling show of seamanship, we picked up mooring under sail – must be fifteen years since we last did that.
We attempted to go to a beach bar for dinner, but there was a big swell breaking on the beach. As I stepped out of the dinghy, a wave caught the back of the dinghy and sent me sprawling full length into the water. We went back to the boat so that I could change into dry clothes where we decided that discretion was the better part of valour and stayed in for the night.
3 March 2012 Charlestown, Nevis
Our horse riding was booked for ten o’clock and we weren’t sure how long it would take to get there, so we dinghied into Charlestown at half past eight. We were in town very early, so we decided to walk to the riding stables thinking that it would loosen up our legs nicely. We didn’t have a map, but I thought that it was only a couple of miles. It turned out to be more like four miles, so the last half an hour was a bit of a route march. We arrived, hot and sweaty with five minutes to spare.
The ride was pleasant - along trails and the beach for the first half. Then the return leg was on quiet roads and through a local village - the guide was very informative about the history and plants of the island. I managed to cope with the thoroughbred horse that I’d been given, but we were both disappointed that there was no cantering. Our horses were ex-race horses and we could feel the pent up energy waiting to be released. It was a big group of seven people and the guide felt that some people wouldn’t be able to control their horses if they took off.
We had lunch in a bar on the beach and caught a bus back into town. Glenys wanted to walk to the old fort on the headland, which was a little difficult to find. There were no signs, but we eventually found it inside a compound hidden behind some derelict apartment buildings. It's an old British fort that is now in ruins, complete with cannons half buried in the long grass. Not a tourist attraction at all.
We walked back along the beach to the dinghy dock and collapsed onto our boat for a quiet afternoon and evening – a good day out.
4 March 2012 Charlestown, Nevis
The damn beach bar was booming out loud music again after midnight – unfortunately there’s nowhere else to go. We decided to chill out today, go walking tomorrow and leave on Tuesday.
Glenys just mooched about all day, while I was a little more productive, sorting out some admin in the morning. I finally managed to sort out our various bank accounts and get money moved to the correct places – it’s only taken a month.
The bottom of the boat was last anti-fouled just before we bought the Alba nearly a year ago, so the chemicals are wearing off and we’re starting to get a significant amount of growth. I’m hoping to last until we get hauled out in the USA in October, so in the afternoon, I donned my scuba gear and spent an hour or so scraping the barnacles and weed from the bottom of the boat. I only managed to do half the hull – I’m scraping it with a plastic scraper hoping that I don’t remove too much of the soft, ablative anti-fouling. I’m trying to remove the growth and expose new antifouling. It’s a nasty job because I spend most of the time on my back with water trickling down my nose.
5 March 2012 Charlestown, Nevis
We were up early and caught a bus from Charlestown just after eight o’clock, which took us up to Gingerland which is the location of many of the old plantations. We walked up to the Golden Rock hotel where we picked up a hiking map showing the route up to “The Source”.
We had a very pleasant four hour hike taking us through some lovely rain forest to a small waterfall which is the source of water supplied to the Golden Rock Estate. The route follows the centuries-old iron pipe which brings water down the mountain. The first half is a gentle hike along easy paths, but the route then becomes a little more challenging with steep paths, old concrete steps and finally a 120 foot iron ladder up to a small pool under a waterfall.
On the way back down, we spotted a Green Vervet monkey, which looked very guilty as it ran away from a banana tree in someone’s garden. The locals tie big seed bags around the ripening bunches of bananas to try to keep the pesky monkeys at bay. We arrived back at the hotel at lunch time, but we took one look at the very stylish patio restaurant and decided it was too up market for us. Instead we cadged a lift off a taxi to the supermarket at Gingerland and then caught a bus back into Charlestown. We ended up in the Café Des Art which has a very nice shaded courtyard and serves great sandwiches. It seems to be the place where all the local ex-pats congregate, which made the place feel very colonial.
We cleared out of customs and went back to the boat to get ready to sail tomorrow. I tried to run the dive compressor to fill the scuba tank that I emptied yesterday, but the electric motor wouldn’t start. I’ve been having trouble starting it for a few weeks now and after some investigation I think that there’s something wrong with the power being produced by our generator. This is not good news - it’s bad enough not being able to fill dive tanks, but if it gets any worse we’ll not be able to run our watermaker. This is another thing to be sorted out when we get to St Martin.
6 March 2012 Charlestown to Simpson Bay Lagoon, St Maarten
We were up early and left at half past six. We motor-sailed between St Kitts and Nevis, which was hard work in the big, confused seas. Once we had negotiated the rocks and shallows, we set a course for St Barts on a fast reach. The seas settled down a little, but we still had large waves which would occasionally break over the cockpit.
After a few hours, I went to check the fishing lines and noticed that we were trailing a thick, blue polypropylene rope. It appeared to be caught on our stern gear and must have been floating in the water, probably from a fishing boat. My “birds” fishing line had snagged the rope, so I tried to drag the rope on board using the fishing line, but the force was too strong and the 60lb steel trace broke – I lost a lure and broke some of my beloved birds. We hove-to to reduce the boat speed with the intention of trying to snag the rope with a boat hook. Fortunately the act of heaving-to dislodged the rope and it had disappeared without me having to do any messing about.
We carried on towards St Barts and hooked a big fish. I started to increase the friction on the reel clutch, but it broke the fishing line. I’m a bit cross with myself because the fishing line has small nicks and twists and I’ve been meaning to replace it for a month now – I’ve lost another lure because of worn out kit.
At midday, we were only twelve miles from St Barts, so we decided to carry onto St Maarten. We arrived in Simpson Bay at half past four and anchored under sail because we didn’t know whether there was still some rope attached to the propeller. I donned my snorkelling gear and found that the stern gear was free of any rope and there’s no noticeable damage.
The anchorage was very crowded and extremely rolly, so we went through into the lagoon. It’s an interesting process - the bridge opens three times a day and boats jostle for position in a loose queue waiting for the opening. Once the bridge was open, we motored through the narrow channel passing the bar at the Yacht Club where a small crowd watched and waved at the procession.
We anchored next to “Notre Vie” and cracked open a nice cold beer as the sun went down.
7 March 2012 Simpson Bay Lagoon, St Maarten
I was up at seven o’clock on a mission to leave here in seven days’ time. St Maarten is a very dangerous place because it’s easy to get sucked into waiting to get work done on the boat and start to party every night. If we want to get the most from the British Virgin Islands and the Bahamas, we need to leave as soon as possible. On the other side, as we move further west, it’s unlikely that we’ll be able to get anything technical done on the boat without paying an absolute fortune.
We had a day of running around. We listened to the local cruisers net and then I shot off to drop off one of our cooking gas bottles to get it filled. I came back, picked up Glenys and went to clear in. This was fairly painless apart from paying $61US and getting five mosquito bites on my legs while filling in the interminable forms – Why, Oh Why don’t I learn to take mosquito repellent with me when I go ashore?
Once cleared in, we walked around the local area, picked up a package that my mum had sent out by FedEx, took some money out of a cash point and bought a case of beer. We dropped the beer off at the boat and then went to a chandlers, where we spent $300US on parts so that I can make a pump out point for our holding tank and do some other jobs.
We went back to the boat for lunch and I had a look at the generator. I’ve received an email from the Panda Fischer technical support in the UK, which says that there’s a Voltage Control System which is supposed to maintain the voltage at 230V - when there’s more electrical load the generator is supposed to run faster. The system operates a small dc motor that turns a worm gear attached to the generator throttle. I found that the dc motor has been disconnected and the worm gear has been locked off in one position. The generator is producing 237 Volts with no load and 217 Volts when the water maker is running. I connected the dc motor and tried it again, but the worm gear doesn’t move. It’s obviously been like this for nearly a year now.
I scooted around trying to buy other parts and arranging for an engineer to come and look at our generator, which may not be until next week – I can feel myself being sucked into the vortex and not leaving here for three weeks…
I opened the package from the UK and found that I’ve been sent the wrong gasket for the exhaust elbow – bummer. I’ve been waiting for this for over a month now and they’ve sent me the wrong one. I went to the local Volvo mechanic and they haven’t got one so I’ll have to go over to the French side and try to get one there. Again, we will probably have to wait a week to get it shipped in.
We went to the Yacht Club to drown our sorrows with John & Sunny from “Notre Vie” and met Kent and Dawn from “Kristy”.
- Next >>

domain: geography


text:
Spending a weekend with my Nan | A lovely sky over the Park in Nottingham
A sunny walk in Stamford | The Bridge near MediaCity, Salford
The wonderful Fred Aldous store + photobooth, Manchester | Amazing cakes in Teacup, Manchester
Watching Round the Twist, Girls, Louis Theroux
Reading The Psychopath Test, The Color Purple, Oh Comely
Catching many trains (I've just discovered that there is a 'Two Together' railcard for two people catching the same trains - thanks Sally!)
Giggling to David Sedaris' live show
Buying tickets to see Macauley Culkin's band The Pizza Underground (!)
Planning our summer UK road trip, thanks for all the brilliant tips!
Looking forward to meeting Janet next weekend for lunch, picnics in the park, seeing friends and publishing a new zine.


text:
Dysbiosis, inflammation, and response to treatment: a longitudinal study of pediatric subjects with newly diagnosed inflammatory bowel disease
Posted on 13.07.2016 - 05:00
Abstract Background Gut microbiome dysbiosis has been demonstrated in subjects with newly diagnosed and chronic inflammatory bowel disease (IBD). In this study we sought to explore longitudinal changes in dysbiosis and ascertain associations between dysbiosis and markers of disease activity and treatment outcome. Methods We performed a prospective cohort study of 19 treatment-naïve pediatric IBD subjects and 10 healthy controls, measuring fecal calprotectin and assessing the gut microbiome via repeated stool samples. Associations between clinical characteristics and the microbiome were tested using generalized estimating equations. Random forest classification was used to predict ultimate treatment response (presence of mucosal healing at follow-up colonoscopy) or non-response using patients’ pretreatment samples. Results Patients with Crohn’s disease had increased markers of inflammation and dysbiosis compared to controls. Patients with ulcerative colitis had even higher inflammation and dysbiosis compared to those with Crohn’s disease. For all cases, the gut microbial dysbiosis index associated significantly with clinical and biological measures of disease severity, but did not associate with treatment response. We found differences in specific gut microbiome genera between cases/controls and responders/non-responders including Akkermansia, Coprococcus, Fusobacterium, Veillonella, Faecalibacterium, and Adlercreutzia. Using pretreatment microbiome data in a weighted random forest classifier, we were able to obtain 76.5 % accuracy for prediction of responder status. Conclusions Patient dysbiosis improved over time but persisted even among those who responded to treatment and achieved mucosal healing. Although dysbiosis index was not significantly different between responders and non-responders, we found specific genus-level differences. We found that pretreatment microbiome signatures are a promising avenue for prediction of remission and response to treatment.
CITE THIS COLLECTION
Shaw, Kelly; Bertha, Madeline; Hofmekler, Tatyana; Chopra, Pankaj; Vatanen, Tommi; Srivatsa, Abhiram; et al. (2016): Dysbiosis, inflammation, and response to treatment: a longitudinal study of pediatric subjects with newly diagnosed inflammatory bowel disease. figshare. Collection. https://doi.org/10.6084/m9.figshare.c.3598127.v1
Select your citation style and then place your mouse over the citation text to select it.

domain: medical


text:
In a recent announcement, McDonald’s, the Chicago-based fast food chain, has revealed its plans to eliminate self-service soda stations at all of its restaurants in the United States by 2032. This decision is part of McDonald’s efforts to enhance the customer experience and ensure consistency across its various offerings, including in-person dining, online delivery, and drive-thru options. While it has not been specified whether this change will extend to locations outside the U.S., it represents a significant shift in how customers will access their beverages at McDonald’s.
McDonald’s USA has confirmed its intention to remove self-service soda machines in an email to The Associated Press. The company aims to create a standardized experience for customers and crew members throughout its entire chain. This move is part of McDonald’s broader strategy to streamline operations and ensure consistency in its service offerings.
By eliminating self-service soda stations, McDonald’s seeks to provide a more uniform experience for customers, regardless of the location they visit. This change will help maintain brand standards and ensure that patrons receive the same level of service and quality at any McDonald’s restaurant they choose.
While self-service soda machines have been a staple at McDonald’s for years, the company plans to replace them with behind-the-counter soda machines. This transition is already underway in select McDonald’s locations across the country. Behind-the-counter machines are not new to the fast food industry, as other chains have already adopted this setup.
The decision to eliminate self-service soda stations was likely influenced by several factors, including financial considerations, sanitation concerns, and the need to adapt to changing consumer preferences. Consumer behavior has evolved over the years, with a notable acceleration during the COVID-19 pandemic. More customers are opting for digital and online delivery sales, leading fast food chains to adapt their operations accordingly. McDonald’s decision aligns with these shifting preferences and its focus on enhancing drive-thru and delivery capabilities.
McDonald’s has experienced a surge in digital sales, comprising app, delivery, and kiosk purchases. These digital sales accounted for nearly 40% of the chain’s systemwide sales during the second quarter of 2023. The company’s revenue rose by 14% to $6.5 billion during this period, exceeding analysts’ expectations. McDonald’s success in the digital space reflects its ability to meet changing consumer demands and leverage technology to drive sales.
McDonald’s locations in Illinois have already begun phasing out self-service soda stations, serving as a testing ground for the company’s broader plan to transition away from self-service machines. By piloting the change in specific locations, McDonald’s can gather valuable insights and make any necessary adjustments before implementing the new system nationwide.
While McDonald’s is known for its self-service soda stations, other fast food chains have already embraced behind-the-counter soda machines. These machines, operated by crew members, provide customers with their preferred beverages without the need for self-service. McDonald’s decision to adopt this approach aligns the company with industry trends and fosters consistency within the fast food landscape.
The COVID-19 pandemic significantly impacted consumer behavior, accelerating the adoption of digital and online delivery sales. As customers sought contactless options and convenience, fast food chains like McDonald’s had to adapt their operations to meet these shifting demands. The decision to eliminate self-service soda stations reflects McDonald’s commitment to staying relevant and catering to evolving customer preferences.
To meet the increased demand for drive-thru and delivery services, McDonald’s and other fast food chains have invested in enhancing their drive-thru capabilities and strengthening partnerships with food delivery apps. By prioritizing these channels, McDonald’s can provide customers with a seamless and convenient experience, ensuring they can access their favorite McDonald’s meals with ease.
McDonald’s digital sales, including app, delivery, and kiosk purchases, have played a significant role in the company’s financial performance. During the second quarter of 2023, these digital sales accounted for nearly 40% of McDonald’s systemwide sales. This success demonstrates the effectiveness of McDonald’s digital strategy and its ability to adapt to changing consumer preferences. The company reported a 14% increase in revenue, reaching $6.5 billion during the second quarter of 2023, surpassing analysts’ expectations and showcasing its resilience in navigating challenging market conditions.
While McDonald’s has benefited from price increases in recent quarters, the company expects these increases to moderate as inflation rates stabilize. Chief Financial Officer Ian Borden highlighted the potential future moderation of price increases during McDonald’s Q2 earnings call. This projection indicates that McDonald’s will continue to focus on maintaining affordability for its customers while navigating market dynamics.


text:
Your Rotaid 24/7 AED Cabinet With Monitoring is designed and built for the outdoors. An on-board alarm system, built-in heating system and rock-solid construction ensure the best possible protection for your AED investment: not only now, but for many future years. Your life-saving system is monitored 24 hours a day. Any use is immediately detected. Your AED’s operational status is continuously checked and ensured. Any maintenance needs are automatically transmitted to those who need to know. No more physical visits to check your AED’s status are necessary as it’s monitored 24/7.
Rotaid 24/7 comes with its own mobile internet connection, allowing stand-alone operation, in both indoor and outdoor environments, and remote and centralised configurations.
Easily connected via Rotaid’s web-based portal, access to your life-saving system is ensured at all times. Monitoring, changing, adapting and managing your system can be realised anytime, everywhere and with any device.
Rotaid 24/7 assists you in the registration, operation and maintenance of your system. It will automatically alert you when you need to take action. During the lifespan of your system, you can adapt individual aspects as and when needed. Renew your equipment, change your responder team, move your AED location, customise your alarm: Rotaid 24/7 will adapt.

domain: design


text:
See, Buy, Splash
If you like Indah (and so does Gigi Hadid, which would put you in reasonably good company), this Miami Swim Week you’ll be able to watch the brand’s show live streamed, and buy products direct from the runway.
It all happens Sunday, July 23rd at 10:30 PM at the W South Beach Vintro Tent.
Not in Miami? No problem. The live stream will be available on their social media channels (@indahclothing), and then for purchase online immediately after the show at www.indahclothing.com.
[portfolio_slideshow id=32082 align=center width=699 click=advance thumbnailsize=40 showcaps=false]
Indah, meaning “beautiful” in Indonesian, is an eco-friendly brand based in Bali known for its bold, inventive, and alluring collections. The brand has been a longtime favorite of celebrities and digital influencers such as Gigi Hadid, Kylie Jenner, Rocky Barnes, Alexis Ren, and Hailey Baldwin, and has been featured in prominent publications including Vogue, Cosmopolitan, Elle, Marie Claire, Refinery29, and Sports Illustrated.
But the brand also has its sights on new shores.
“We are looking to delve into festival wear and party dresses,” said designer Libby DeSantis. “This is an exciting opportunity for us to showcase our favorite looks from a variety of projects.”
We are looking to delve into festival wear and party dresses
In the spirit of Indonesian beauty, expect to see Indah’s defining aesthetic on the runway as bohemian flair meets vintage Vogue. “Through our colors and prints this collection will allow you to find yourself in Ibiza in 1977 with a flower in your hair and a cocktail in your hand,” said DeSantis. Forever a free spirit, DeSantis’ designs will feature exotic influences from both her home in Bali as well as inspiration from her travels around the world.
Indah’s defining aesthetic is bohemian flair meets vintage Vogue
This year INDAH will be the first swimwear brand to make its foray into the “see now, buy now” movement. A 12-piece boho chic capsule collection shown on the runway at Miami Swim Week will be live streamed on their social media channels (@indahclothing), and will be available to purchase online immediately after the show on their website: www.indahclothing.com.
About Indah Clothing
Indah is a dream factory. Some days it is a sacred space and others it is a dance floor. Indah is remarkably known for their daring, sexy swimwear, and bohemian luxe ready-to-wear collections. Indah is made by hand and created with love and designed by Libby DeSantis. Indah was made to create beauty and innovation in the art of simplicity. Everything produced by Indah is done in house – and everyone in our house is treated with respect and paid fairly for their efforts. Indah is a platform for change, building their very own eco friendly Batik factory that is already setting a new standard on the Island. Indah is also committed to giving back; each collection is tied to a charity by one of its beautiful handmade prints.


text:
I am delighted to announce that I will be a 2014 Britten-Pears Young Artist and will play the role of Kate Julian in a new production of Britten’s Owen Wingrave directed by Neil Bartlett and conducted by Mark Wigglesworth with a very exciting cast of singers in the Aldeburgh Festival, full details to follow. The production will also be going to the Edinburgh International Festival in August.
- 20/03/21 - 10/03/22 Grange Park Opera in Anywhere at YouTube
- 07/02/22 Wesendonk Lieder in London at Hampstead Parish Church
- 19/02/22 La Forza del Destino by Verdi in London at St John’s Church, Fulham, SW6 1PB

domain: artistic


text:
Gene Simmons sits down for an interview with the Evening Standard during KISS’ ‘End Of The Road World Tour’ in 2018-2019. He did not reveal the topic of the last gigs, but he did say that the band ‘ramped things right up’ for the tour. Then he commented on the performances of other bands, notably The Byrds: “When I was a youngster, bands would frequently disappoint me live. When I saw The Byrds, I thought to myself, ‘I really like that song, but maybe I could close my eyes and appreciate it even more.’ Onstage, there was nothing going on. “All they were doing was standing in front of their microphones.” In comparison to other artists, the singer said of KISS’ stage dynamics: “We’ve always wanted to be the band that we never got to see perform.” Working our tails off to give the fans the most bang for their cash. Ed Sheeran is incredible and can sell out Wembley Stadium with just a guitar. But I’m not going to do it.
I have an excess of energy within me. “I’d like to blow up the sky.” Almost all of the band’s live shows have included complex costumes, pyrotechnics, and fireworks over the years. With that in mind, Simmons once stated that KISS concerts inspired numerous artists, including Paul McCartney. During an interview with Classic Rock, he noted that his band’s gigs provided people with what they needed in terms of entertainment. “There’s nothing negative about it; we don’t do political commentary.” There are enough problems in the world without males who wear more makeup and heels than your mother waxing poetic and prolific on a variety of topics. They ought not to. We make you forget about the traffic jam and the argument you had with your partner, and just’magic time’ — ‘electric church.'” KISS’ final year of touring is planned to be 2023, especially since their tour was canceled a few years ago owing to the pandemic and health difficulties. But the band’s frontman did not call it quits after this year’s shows. In another interview, Simmons hinted at new gigs with the Gene Simmons Band that will require ‘less work’ in the future. He also said that he and Gary Hamilton would collaborate to make 25 films over the next five years. The first installment of the planned project is now under construction. Renny Harlin will direct the film ‘Deep Water.’

domain: entertainment


text:
June 5, 2012
After earning some pretty big stripes in radio, programming visionary Brian Philips decided to take a leap into "The Great Unknown" that was the fledging Country music video channel, CMT, over 10 years ago. As he notes below, the transition wasn't exactly smooth, but as CMT's growing ratings indicate, it has been increasingly successful. Now, with the latest-and-greatest CMT Awards show kicking off June 6th, Philips offers insight into his recipes for cable TV success ... and how Country music - and radio - remains a big part of the mix.
What made you decide to leave radio for the cable TV world - and has the segue been all that difficult?
No, I got lucky. After Viacom acquired CMT for the MTV Music Group in 2001, John Sykes asked me to consult CMT. I was living in Atlanta, working on the Q100 launch for Susquehanna. But the breakout success of our original Wolf in Dallas struck Sykes as an interesting story; he was curious, we talked. Soon I visited MTV headquarters. After one meeting, my adrenaline was surging. I walked down to the corner of 44th and Broadway, called Joel Katz on my cell -- "I've just found where I belong."
Remember, Susquehanna was a terrific radio company, and I loved my run there, so this was not an easy call. The segue to TV was survivable because Viacom surrounded me with great people. I was clueless about TV at the time, but they were patient; they backed me to the hilt. Since then, they've always enabled us to staff our Nashville, Santa Monica and New York offices with winners, all A+ students. Since 2001, we've grown from 36 million households to 92 million.
What kind of differences between radio and cable TV did you have to overcome?
Different mindset. In radio, a lone programmer can "hear" a new station in his head, in his imagination, and spontaneously bring it to life with just a little money and small circle of people. A handful of energetic people can quickly reinvent a station with new talent, fresh creative, new music. Rewrap the van! The fundamental idea for The Wolf/Dallas-Ft. Worth was born in a flash; I wrote it on a notepad on a car ride to DFW. At 99X/Atlanta, we were flying without instruments, building a pop/rock/alt station that had never existed before.
Television, by comparison, takes an army. CMT's programming is shaped by our EVP/Development, Jayson Dinsmore (formerly NBC), and his team in Santa Monica. SVP John Hamlin (formerly 60 Minutes) handles all of our Nashville production, including these "Crossroads" spectaculars and the CMT Awards. My old 99X friend, Leslie Fram, turned out to be the perfect for SVP/Music; she loves Nashville. Mary Beth Cunin came from Disney; she handles all program scheduling and acquisition ... an enormous job.
Press SVP Lisa Chader (from Comedy Central) tries to stop me from shooting off my stupid mouth in the press. Dee McLaughlin is SVP/Brand Strategy, Creative and Marketing; she comes from Virgin North America. Suzanne Norman is CMT's Business Operations and Strategy SVP. She is as buttoned-up as I am free-wheeling. She functions as the part of my brain that was lost somewhere along the way. Lucia Folk leads up our massive Public Affairs department; her work atones for the trouble we get into.
My brilliant Nashville assistants Leeanne Lisk and James Hunsberger supervise me. They keep track of the passes, sunglasses, iPhones, important papers and clothing that I leave all over the building ... and all over America.
CMT.com is overseen by Martin Clayton, who founded it 15 years ago. Research, social marketing and digital initiatives, like everything we do, live in Nashville with support from teams in N.Y.
The legendary Chet Flippo is our Editorial Director, one of the original Rolling Stone guys. On his wall, he has the cover from his 1978 Willie Nelson interview edition of RS!
Advertising Integration is a big deal in TV. That's SVP Anthony Barton's expertise; he supports our huge Integrated-and-Advertising Sales effort, which is N.Y.-based. Similarly, distribution on all platforms is masterminded by a team at Viacom.
So my job isn't exactly like being the GM of a radio station. It allows me to traverse both the business and creative worlds. It has taught me how to run a much larger team, because each person has specific knowledge that makes them the envy of the industry.
They teach me.
Who are your role models?
Van Toffler, Lorne Michaels and Irving Azoff.
You are also involved in the radio side, with CMT Radio Live With Cody Alan...
Yes, my bud from The Wolf/Dallas! CMT Radio has grown wildly ... a powerful extension of CMT. Cody's show is on 122 stations, with more on the way through our Cumulus syndication deal. It's not only profitable, but we see that CMT -- the linear TV channel -- has higher ratings in markets where Cody is on the air. Another great way to spread the brand and the music. I love having a functioning radio operation in the building; it feels close to my roots. Cody is a star.
Cody's studio is in our building in Nashville, and sometimes on my way out of the office at night, I'll stop by and check in with them, settle into the studio, and suddenly I'm back in the world I left behind. I can relive my PD life for a minute ... until Cody tells me to leave.
Are other radio projects in the works for CMT?
We have more radio products coming -- weekend specials, daily services and more. We'll grow to meet the needs of our stations.
Country radio perennially faces the challenge of how much new artist product to play, as well as when new music from established artists become less, shall we say, "contemporary." How does CMT balance the generation issue?
We want to be at the forefront of any new musical movement, to lead and innovate with good judgment, but also take risks and provoke reactions when we can. A show like "Crossroads" cross-pollinates the new with the old, and weaves new flavors and styles into our music. We're conscious of tradition even as we strive to introduce the next wave. Our audience is active 18-49 year-olds.
So how does one discern when a Country artist moves from the current "era" to a past one?
No two cases are alike. Whenever there's a "changing of the guard," the audience will give you a tremendous amount of guidance as their tastes evolve. I don't think it's up to TV or radio programmers to consciously try to push the genre in a direction of their choosing.
I look at Nielsen ratings every day at 3:30 and they tell me exactly what America was thinking the night before -- always humbling. I know programmers spend a lot of time doing the same thing, and they deal with 10 times more ratings analysis in the PPM world now then during my radio career.
Let the audience help you decide when its time to move an artist along. And we never write any artist off. One song can change everything. There's no substitute for talking directly to your audience via focus groups and panels. It's the greatest theatre in world. Is it sick that I love focus groups so much? I also love watching social and reading message boards; we all crave feedback every minute.
But how can the audience tell you they want new music or artists they haven't heard yet?
That's the gig. You feel trends and tremors, not just in the research, but through social media and direct interaction with your audience. They're talking ... they're consuming new music online. We just have to pay attention.
I love it when something in our world catches the attention of my peers at MTV and VH1 in New York. I'll hear, "What's the deal with this guy Eric Church? How BIG is Jason Aldean?" They're tapped in, and they know who is making waves beyond Country.
Much like the waves that Shania Twain, The Dixie Chicks and Taylor Swift made, changing the landscape of Country music. It feels like we might be on the cusp of some seismic changes, exciting times in Nashville.
Let's talk award shows. On top of there being the Grammys, American Music and Billboard Music Award Shows, the CMT Awards also go up against the ACMs and the CMAs within the same music genre. Is there a constant effort on your part to outdo all the others?
We set out to throw one big kick-ass party. We're a little looser, a little riskier and generally louder. We work to bring in surprising characters from the larger culture who happen to like our music.
Our choice of Kid Rock as a host worked in 2010 and last year. Why Kid Rock? The answer is that Kid Rock may be from Detroit, but he has "Country" in his bones. He's got a Nashville home (when he's not passed out at Hank Jr.'s house), and plays and sings with all of our friends. Probably not a move any of the other awards shows have made, but it fit us perfectly and delivered monster ratings.
Are you ever concerned that the pop or movie star's appeal might alienate the more conservative Country music fans' sensibilities?
Stars outside of the narrowly-drawn lines bring in the mass audience. Our stars love being part of a larger cultural event. We don't like contrivance, but if we can create a genuine connection, we've earned new converts to our music.
But even on a national scale, aren't you concerned about too much pop/rock influence on what is still a Country music Awards show?
We are always surprised at the depth and breadth of the CMT audience's tastes. Maybe 20 years ago, it was easy to find Country music fans exclusively loyal to Country. Today, I defy you to find a fan under the age of 50 who listens exclusively to one kind of music. Look at their iTunes collection.
I learned awards shows from (MTV Music Group President) Van Toffler. If you set up expectations correctly, put the right people in the room -- hire the right writers, the freshest creative team and attract the right stars -- you set the atmosphere and the tone. Let the stars unwind and have a good time ... then the surprises, the big TV moments will take care of themselves.
Again, it goes back to audience knowledge; audiences today know if something is contrived, if it's being done for shock value or it's a rip-off. It's a challenge we rise to on an annual basis, reinventing the show. We want people to walk out of the 2012 CMT Music Awards believing this is the best party we've ever thrown.
Is it hard to accommodate all the artists who want to be on the show?
Yes! It's hard because there are always more worthy bands than can fit into a two-and-a-half-hour show, which from the viewers' point of view, is good stretch of entertainment. Three-hour shows seems a little long to me. Two-and-a-half hours put pressure on us to jam the music and keep the show moving.
Looking into CMT's other programming, for years MTV has been criticized by those on the label/music side for emphasizing reality shows and abdicating its efforts to break bands via music videos. Has CMT dealt with such sentiments -- and how do you respond to that?
Check your watch ... it's 2012. We, as the Music Group, seem to have moved past that kind of criticism. I don't see viewers resenting the fact that they can't see Men At Work or Duran Duran videos on MTV anymore. MTV is enjoying its most successful era ever! Snooki is helping to put my kids through college! Music videos are now consumed in a lot of different ways; people are plugged in, and our new platforms will deliver more music than ever before.
Look, we'll always remember the early days fondly, but the world has clearly mutated in the way consumers view music.
But with all that said, CMT still has more big music franchises than just about anybody on TV. "Crossroads," CMT Music Awards, Artists of the Year, Top 20, "CMT Insider," VJ- for-a-Day video blocks. Music will always be the backbone of the channel.
How has CMT capitalized on the reality show boom?
Our two biggest hits of all time both aired this year, back to back! The CMT audience exploded for these shows. "Bayou Billionaires" and "My Big Redneck Vacation." The first season of "Vacation" took a blue-collar family from Louisiana and sent them on summer vacation to the Hamptons. The next season premieres on Wednesday, June 6th, right after the Awards show. This time, we sent the same great family to England, put them up in a castle in near Manchester, and watched them wreak havoc across the English countryside.
"Bayou Billionaires" tells the story of a hard working family who discovered that their property was atop a huge natural gas deposit -- and suddenly they became instantly wealthy. The Dowden family is a fantastic group of people -- unspoiled, enjoying their newfound riches, yet grounded enough to take care of each other.
We're always on the lookout for people who are a bit loud and a bit crazy, but who also have real heart and humor in the way they interact with each other.
Is the CMT audience also enamored with families like the Kardashians?
CMT viewers aren't heavy viewers of this type of "reality" (or at least they tell us they're not.) Besides having extraordinary BS detectors, the CMT audience embraces genuine humans with heart and humor, even though reality characters tend, by nature, to be exaggerated, over-sized.
So sex doesn't sell on a CMT reality show...
Not sex for the sake of shock value. At the risk of sounding like Bill Clinton on a bad day, "It depends on what your meaning of the word 'sex' is." You could argue that our biggest artists are sexy. "Attractive" people are just that -- attractive to others, attractive to viewers. But I've got seven kids under the age of 13 ... and I like to be able to watch CMT, for the most part, with my family. Sex doesn't "sell" on CMT, but romance, heart, larger-than-life characters and great stories do.
CMT families are smart, grounded and tech-savvy. They value time spent watching TV. That's part of their family time. They'd be disappointed to see a salacious show on CMT.
So there won't be a "Housewives Of Nashville" on CMT any time soon?
No ... as tempting as that may be. I think we might have a few casting ideas ... I don't think the CMT audience has any appetite for these formulaic shows where "real" women break chairs over each other's heads in drunken, bleeped-out stupors. Viewers would reject it, and our advertisers wouldn't want to be in it. Cable is a terrific business, and we need premium advertisers
Advertisers love CMT because they know their spots won't get sideswiped by nasty content. This is a good environment for their products because we attract multiple generations of viewers to our shows. We want to mirror the appeal of a Country music stadium show -- attracting all ages. We don't want parents to fear their children will be scorched by some terrible thing that someone will say, or sing. This is not rock or pop. They'll hear solid music and see well-told stories from a bunch people they'd like to hang out with. It might get a little rowdy and wild at times, but its heart is always in the right place.
Watch the CMT Awards Wednesday night at 7p CT, 8p ET. We're going to launch Carrie Underwood out of a circus cannon. And give viewers a backstage glimpse of our luxurious "Willie Nelson CMT Awards Smoking Lounge."


text:
General Castaños, 6, Ciutat Vella, 08003 Barcelona, Spain – Great location - show map
|Double or Twin Room with Breakfast|
|Single Room with Breakfast|
|Double or Twin Room|
5 Reasons to Choose Hotel Lyon
2345 properties in Barcelona
Manage your bookings online
Booking is safe
Free! Pets are allowed. No extra charges.
Free! WiFi is available in all areas and is free of charge.
Public parking is available at a location nearby (reservation is needed) and costs EUR 25 per day.
- 24-Hour Front Desk
- Air Conditioning
- Non-smoking Rooms
Area Info – Great location - show map
- Barceloneta 0.1 miles
- Museum of Catalan History 0.1 miles
- Santa Maria del Mar 0.1 miles
- Estació de França - Railway Station 0.2 miles
- El Born Centre Cultural 0.2 miles
Most Popular Landmarks Nearby
- Picasso Museum 0.2 miles
- Plaça Catalunya 0.8 miles
- Casa Batllo 1.2 miles
- Sagrada Familia 1.5 miles
- Sants Estacio 2.6 miles
2:00 PM - 12:00 AM
Until 12:00 PM
Cancellation and prepayment policies vary according to room type. Please enter the dates of your stay and check what conditions apply to your preferred room.
Children and Extra Beds
Children cannot be accommodated at the hotel.
There is no capacity for extra beds in the room.
Pets are allowed. No extra charges.
Cards accepted at this property
Hover over the cards for more info.
100% Verified Reviews
Real guests. Real stays. Real opinions.
Based on 334 reviews
Good: 7 – 9
Okay: 5 – 7
Poor: 3 – 5
Very poor: 1 – 3
Value for money
Show reviews from:

domain: travel


text:
ravings, rantings and ramblings
I have grown up and seen you grow old.
But you have grown old and ugly. So ugly that I refuse to look at you now.
I hate saying that I was with you once, playing with you in lush green fields, laughing and soaking the winter sun. Now, I could pass you by and not look at you.
Your skin has calluses that refuse to heal. All your goodness being hidden by crime, one worse than the other. One horrific than the other.
I don’t think I know you anymore. Where once people would go out of their way to help, now (they) turn a vacant eye over those lying bloody and needy.
Look at what you have made me into. Cynical. Critical. I don’t trust that easy. I am hopeless. I don’t think anybody is safe with you, specially women and children. I openly confess my dislike for you. I wasn’t like this a few years back, you know. Now, you are nothing but a pack of lies.
You have cut your umbilical cord that once connected me to you.
You don’t make me homesick anymore. You just make sick.

domain: literature


text:
bari cordia federspiel
to receive their most current artwork
16 x 20
October, 7th 2017
A magical balloon sails away to ... somewhere. Painted in acrylic on stretched canvas with painted edges. This painting and two others if mine are showing (and for sale) at ARTAPALOOZA at the Liberty Building on Main Street in downtown Spokane (above Auntie's).


text:
‘Jenny Wren’ Sterling Silver & Copper Pendant
Layer upon layer of Sterling Silver and Copper using cold connection techniques, this little Jenny Wren sits proudly creating shadows and depth. Hand cut from Copper the image is framed by a Sterling Silver ring and backing, all held together with ‘smashed’ rivets. The pendant hangs from a Sterling Silver bail on a 45cm long black cord which joins at the back of the neck with a heart-shaped clasp.
Pendant measures: 32mm diameter
Out of stock


WINNIPEG - Bobby Ryan didn't look out of place on Ottawa's top line, but he knows chemistry takes time.
Ryan scored the winner Sunday as the Senators downed the Winnipeg Jets 3-1 in NHL pre-season action, while newly minted captain Jason Spezza had an assist and left-winger Milan Michalek scored and added an assist.
"I think there was a few opportunities for us to do things differently, and that's just something that you learn about each other," said Ryan, who was acquired in an off-season trade with the Anaheim Ducks.
"I know that there were a couple passes that Spezz meant for me that I thought were for Milan and they just kind of were a foot or two away and that's a matter of me trying to read off him a little better."
Buddy Robinson scored Ottawa's first goal at 7:58 of the opening period and Ryan added his 26 seconds into the second to give Ottawa a 2-0 lead.
Sens defenceman Erik Karlsson had a pair of assists and Matt Halischuk scored Winnipeg's lone goal.
Karlsson liked what he saw of the Ryan-Spezza-Michalek line.
"It's the first game, you know everybody's trying to feel it out a bit," Karlsson said. "Overall, I think they looked pretty good."
Karlsson's shot from the point 65 seconds into the third period was redirected by Michalek past goalie Michael Hutchinson to make it 3-1. Hutchinson made 29 saves.
Robin Lehner was in goal for the Sens for the first two periods and stopped 17-of-18 shots. He was replaced by Andrew Hammond to start the third. Hammond stopped all 10 shots he faced.
Winnipeg lost its first exhibition game Saturday night in a 4-3 shootout against Washington in Belleville, Ont.
The Jets experimented to start the game and didn't ice their usual top-line trio of Andrew Ladd, Bryan Little and Blake Wheeler.
Little and Wheeler skated with newcomer Michael Frolik, acquired from the Chicago Blackhawks for third- and fifth-round picks in this year's draft.
Ladd, however, rejoined his linemates late in the opening period.
"We started with Frolik and didn't really get much going," Little said. "And even when Laddie came and played with us, we kind of struggled a bit still.
"We're still trying to work out the kinks. We haven't played a game in five months or so, so we're just trying to shake the rust off."
The Jets were sitting a number of their players who had suited up in Belleville, including forwards Evander Kane, Devin Setoguchi and Mark Scheifele.


Although water is a renewable resource, its supply is not inexhaustible. It is unlikely that sufficient new water resources will be found to meet the projected increase in demand for water for food production, as existing water resources are already under pressure. It is vital, therefore, that existing resources be managed efficiently. This is particularly true with regard to agriculture, which utilizes more than two-thirds of the global water used by humans. Continued successful management of the limited amount of water available for agriculture is dependent upon better agronomic practices and an enhanced understanding of genetic variation for water-use efficiency (WUE) among crop genotypes, especially in areas prone to water scarcity. This document presents the proceedings of an inter-agency workshop dedicated to tackling the issue of water-use efficiency and water scarcity. Issues discussed relate to methods of managing water in agriculture, exploring opportunities for saving water and improving productivity by utilizing genetic resources, as well as other agronomic measures. The document is divided into three sections: the first section addresses themes related to water availability, current and future water needs, and water scarcity. The second section focuses on research strategies for a more efficient use of water resources - particularly in olive orchards - while the third section details the potential of genetic resources to manage water scarcity. It also addresses innovative approaches towards exploring the valuable genetic variation within crops, especially olives and almonds. The aim of the undertaking is to facilitate assessment of genetic variation for WUE and measurement of water requirements at the genotypic level, rather than simply at the crop level. Assessing plant genetic resources for complex traits such as those concerning water-use efficiency requires large numbers of samples to be taken. Lack of development of rapid, costeffective methods has hindered the use of WUE in practice and breeding. The effectiveness of characterization is also hindered by the lack of novel 'smart and rapid screens' needed to identify desirable traits in a cost-effective manner. The overview of concepts such as quantitative methods to model traits associated with water-use efficiency can also help in narrowing the phenotype gap. The overall aim of this text is to enhance the use of diversity through characterization, using novel approaches in order to improve productivity, and to ensure that knowledge about ongoing research on efficient water-use of plant genetic resources is readily available to all stakeholders.
Assessment of plant genetic resources for water-use efficiency (WUE): managing water scarcity
Proceedings of the Bioversity International/INRA/IDRC/AARINENA
Workshop for North Africa and West Asia, Marrakech, Morocco, 10-12 October 2005


text:
Food is any material consumed to supply nutrition to an organisms. Food includes any kind of substance originated from a living thing, as well as consists of vitamins, proteins, carbs, unsaturated fats, sugars, or various other nutrients. There are various sorts of food and the kinds transform according to the requirements of the body. Animal items such as meat, dairy products, eggs, poultry, fish, and also other livestock; veggie products such as fruits, vegetables, legumes as well as grains; as well as fruit products such as berries, nuts, as well as delicious chocolates are examples of food. In this post, I will be going over food, its dietary worth, the three sorts of dietary fibers, and exactly how each food helps to preserve or boost the health of the human body.
A well balanced diet plan, according to the USDA, is a mix of numerous foods in the proper percentages. An undesirable well balanced diet usually includes a high-fat meal as well as a high-sugar dish. When people pick to quick for religious, social or various other reasons, they generally choose low-nutrient, high-calorie foods. Fast foods are really delicious as well as gratifying, however incredibly unhealthy. When individuals choose to consume in restaurants, the dining establishment will normally package the food in a manner that makes it very easy to overindulge. read more
Many vegetables and fruits are very high in vitamin C, especially orange and also red fruits. Nonetheless, individuals need a minimum of 30g of vitamin C everyday to prevent vitamin C depletion due to too much consumption. It is not feasible to obtain enough vitamin C from vegetables and fruits alone. To get enough amounts of vitamin C, absorb some dairy items such as milk and yogurt.
Cereals, breads as well as pasta are likewise rich in calories, but people need more than enough cereal as well as pasta to preserve regular body weights. Additionally, some grains contain way too much starch, which can make you feel starving for even more snacks later on. When acquiring food, choose one with great deals of entire grain. Entire grain cereals are healthier as well as have even more fiber than the bread and also pasta options.
When choosing carbs, avoid polished sugar and also white flour. Rather, go with brown rice as well as whole-grain pasta for added nutrients. Various other great selections for carbohydrates consist of legumes (beans), fresh fruits and vegetables.
Vitamins as well as micronutrients are called protective foods. Folic acid, iron, potassium and also vitamins A, C as well as E are typically located in vegetables and fruits, although in some cases found in small amounts in nuts and also seeds. Some studies show that adding these vitamins and also micronutrients to the diet might enhance health. However, even small amounts of these materials can be toxic, particularly if taken in huge amounts. The very best means to consume these vitamins and also micronutrients is by eating a healthy, well-balanced diet regimen. Considering that most diet plans do not supply a balance for trace elements, supplements are the most safe method to obtain them. learn more
Vitamin E has been shown to combat free radical damages. A research study session has revealed that consuming an egg abundant in vitamin E supplies security from prostate cancer cells. Yet, given that a lot of males do not eat an egg every day, this kind of study is really impractical. A better way to get vitamin E is by consuming sunflower seeds, which include sufficient vitamin E to support health for most individuals. Consuming a lot of nuts as well as seeds is additionally advantageous for supplying vitamin E.
Vegetables and fruits are the best resource of nourishment as well as are one of the most advised diet regimen. Yet, most fruits are exceedingly sweet. Thus, it is advisable to eat numerous small-sized dishes throughout the day to keep blood sugar levels secure. Fruit juices ought to be eaten periodically, as opposed to replacing entire fruits. In fact, fruit juices are really bad for your diet plan due to the fact that they consist of a great deal of fructose.
Oils and fats are commonly added to prepare food for usage. Olive oil, canola, corn, and safflower oils, margarine, and butter all have high levels of hydrogenated fat, trans fat, and sugar. Nuts, fresh or ground, are also high in sugarcoated, as they include high levels of fibre. High quality nuts and also seeds, such as sunflower seeds, peanuts, almonds, walnuts, hazelnuts, chestnuts, pecans, pistachios, and others, offer a number of beneficial residential properties, including protein, fibre, minerals, and also vitamins.
Legumes are high in nourishment as well as consist of reduced degrees of calories as well as fat. This enables them to make up a huge part of the diet plan. Nonetheless, specific types of vegetables, such as kidney beans, black beans, chickpeas, as well as lentils, include a variety of unfavorable health concerns. They can raise cholesterol degrees as well as create nausea or vomiting and also vomiting, two of one of the most common negative effects of a normal American diet. They are also high in calories and also fat, making it challenging to get sufficient of them in to lower general weight.
Meat and also fish are outstanding pet resources of protein. They provide the needed fatty acids as well as vitamins to support the body. Meats and also fish are also low in calories as well as fat, making them a superb alternative to meat. Some plant-based foods, including nuts and eggs, provide healthy protein, minerals, and also vitamins, although many of them, specifically those that are high in calories and also fat, can result in weight gain. The primary advantage of a balanced diet is that it offers all of the nutrients as well as vitamins necessary to make certain appropriate health. more info
Due to the fact that many Americans cope with appetite pangs most days of the week, they are specifically at risk to eating the wrong kinds of food. The method, then, for dieters is to find healthy resources of healthy protein as well as calories, which can be located in most of the foods detailed above. Some plant-based foods, like nuts and also seeds, are additionally high in protein and also fat. Most of these resources are much healthier options than processed food, although some plant-based foods may not be healthful in any way. Yet there are likewise lots of healthy choices in this section of the food guide pyramid.

domain: biology


text:
With Christmas being just around the corner, and myself staying with my parents in Melbourne for the Summer, I have found myself doing a whole lot of baking.
First on my list of "Sweet things for Christmas" was scrumptious Chocolate Truffles. Awesomeness was added to this classic with macadamias and dried cranberries.
400g good-quality dark chocolate
300ml cream (can be substituted for light cream)
2 tbsp kahlua
65g dried cranberries
cocoa power (enough to roll the truffles in)
To get started, you need to melt the chocolate, butter, and cream using a double boiler method. That is: place a glass, ceramic, or metal bowl over a saucepan with about 5-10cm of simmering water (see pictures below). Stir the mixture occasionally until the texture is smooth and looks like the picture on the right. Add the kahlua and stir to combine. Chill until firm to touch - I popped mine in the fridge over night.
When your mixture is ready you can begin to prepare the other ingredients. Combine your macadamias and dried cranberries in a bowl. Take a spoonful of the chilled chocolate mixture and a spoonful of the macadamia and dried cranberries and shape it into balls. On a plate, have a good mound of cocoa powder waiting and roll the balls of chocolate, dried cranberries and macadamias until coated finely. Place truffles on a tray or plate and chill until ready to serve.
I hope you enjoy these delicious chocolate truffles that are, trust me, much more than a morsel.

domain: food


NATO Foreign ministers will hold an informal reunion in Oslo on April 26-27 that is expected to discuss the decisions of the Riga summit in December 2006 but also the US missile defense plans and the allied mission in Afghanistan.
The talks will also focus on the cooperation between NATO-Russia and NATO-Ukraine as US tensions with Russia have been rising over Washington plans to install a missile defense system in CEE countries and NATO is seeking Ukraine support for operations in Afghanistan and Iraq.
Romania’s new Foreign minister Adrian Cioroianu had sought to use the occasion to meet US Secretary of State Condoleezza Rice but his plans failed as official statements by the Romanian Foreign Ministry said her agenda was too tight and could not find time for such a meeting.
The summit comes at a time when Romania’s new, mostly Liberal government is considering a withdrawal of Romanian troops in Iraq before the end of 2007.
The reunion will also discuss the future role of NATO in Kosovo as international authorities are negotiating a new status for Serbia’s separatist province.


text:
Regulation and Function of the Neisserial Denitrification Pathway: Life with Limited Oxygen
Virginia L. Clark, Vincent M. Isabella, Kenneth Barth and Tim W. Overton
from: Neisseria: Molecular Mechanisms of Pathogenesis (Edited by: Caroline Genco and Lee Wetzler). Caister Academic Press, U.K. (2010)
Neisseria gonorrhoeae and N. meningitidis can grow anaerobically and/or microaerobically by anaerobic respiration, using the central two enzymes of the denitrification pathway. Nitrite reductase (AniA) converts nitrite to nitric oxide (NO), which is then reduced to nitrous oxide by nitric oxide reductase (NorB). The regulation of expression of aniA and norB is complex, involving multiple transcriptional activators and/or repressors. Transcription of aniA only occurs when oxygen concentrations are low due to the absolute requirement for FNR, an oxygen-sensitive transcriptional activator. When nitrite is present, it is converted to nitric oxide by AniA, resulting in inactivation of the repressor, NsrR, and commensurate derepression and NarP-dependent activation. Expression of norB is controlled by three repressors, NsrR, Fur, and ArsR. Transcription of norB can occur aerobically if nitric oxide is present, by inactivation of NsrR. Fur and ArsR compete for overlapping binding sites; Fur + iron displaces ArsR, causing further derepression of norB. In addition to enabling growth under oxygen-limited conditions, the denitrification pathway may alter nitric oxide concentrations during infection, leading to changes in NF-κB activation and resulting in suppression of the immune response. When a long-half life NO donor is added to mimic host production of NO, gonococci reduce NO from a pro-inflammatory (> 1 μM) to an anti-inflammatory steady state concentration (100-200 nM). In the presence of nitrite, most strains produce a high steady state level of NO, while strains requiring arginine, hypoxanthine, and uracil (AHU) set a steady state level < 1 μM. In meningococci the presence of the denitrification pathway protects the bacterium against the toxic effects of reactive nitrogen species and also alters cytokine production profiles by host macrophages read more ...


text:
One in five youth have a mental health condition, with half of mental health conditions developing by age 14. Yet, less than half of youth with mental health conditions received any kind of treatment in the past year. Undiagnosed, untreated, and inadequately treated mental illnesses significantly interfere with a student’s ability to learn, to grow, and to develop. Since children spend much of their productive time in educational settings, schools provide a unique opportunity to identify and treat mental health conditions by serving students where they already are. (NAMI)
- Up to one in five kids living in the U.S. shows signs or symptoms of a mental health disorder in a given year.
- Most children — nearly 80 percent — who need mental health services won’t get them.
- With large caseloads, school counselors are usually not able to provide enough resources to all students who suffer from a mental illness.
- Experts say that a comprehensive approach, families and school professionals working together, is the best approach to identifying and dealing with mental health issues in schools.
- Whether treated or not, children with mental health issues go to school.
- The problems that students with mental health issues face can tie into major problems found in schools: chronic absence, low achievement, disruptive behavior and dropping out.
- (An Update from IDOE 5/5/23): May is Mental Health Awareness Month – May is Mental Health Awareness Month. During Mental Health Awareness Month, you can show your support for Mental Health by spreading the word in your school and community. FSSA’s Department of Mental Health and Addiction (DMHA) and Project AWARE have created a Youth Mental Health Resources document to help promote student well-being and mental health. Contact DMHA with any questions.
- (CounselorTalk, March 2023): Jennifer Dodson shares a compilation of Mental Health resources shared with her by school counselors in Indiana. You can find that HERE
Question: I like to know the process of setting up therapeutic services in my school.
- I contacted the Bowen Center. We have one about 20 minutes from our school. They are very helpful and willing to come to the school to help.
We have connected with a couple of mental health providers in our area. One services primarily our students with medicaid — providing school based therapy and school based case management.
We also found there was a need for our students with private insurance and lack of providers. The second provider was contacted to service our students with private insurance. They only provide school based therapy services. Each provider gave us referral forms to use. I meet with the child’s parents and discuss counseling services outside of the school. Parents are usually looking for a provider but do not know where to begin. I discuss providers in the community and the ones who come to school. Parents decide if they want their child to have therapy services and how they want them to receive them. I make a referral after I have obtained their permission. Once I refer, the mental health center arranges the intake, sets up appointments and the billing process.Parents sign releases allowing the provider to communicate with the school.
Our process is nearly identical to (the above). The only difference is that parents have us set up the initial intake appt. Also the intake appt takes place at school.
- Indiana has been selected as 1 of 9 states to be a part of the National Coalition for the State Advancement of School Mental Health, through Center for School Mental Health (CSMH). CSMH will provide technical assistance to Indiana schools with use of the SHAPE System, a school performance and mental health assessment system. A benefit of this assessment system is that it will help to expand the capacity for schools and districts to meet the social, emotional, and mental health needs of their students and staff. For more information, please contact Jeff Wittman or Kristan Sievers-Coffer.
- (CounselorTalk, May 2023): IDOE is hiring a Project AWARE Specialist: The Student, School and Family Engagement Team is hiring a Project AWARE Specialist!!!
This position will oversee the management of the Project AWARE grant and sub awardees. They will be responsible for providing extensive support, professional development, and guidance regarding best practices for mental health services for school aged youth. This position will be the liaison between LEAs, DOE, and SAMHSA to ensure that the goals for FY 2022 Project AWARE are being met. In addition, this position will work closely with the Indiana Division of Mental Health and Addictions to provide cross department work.
- Work 2 Days Remotely
- Team collaboration
- Space for creativity, flexibility & professional development
- State Benefits
Experience as an Educator/School Counselor/School Social Worker is preferred. Starting Salary is $59,800. Share your resume via firstname.lastname@example.org
- Project AWARE Fiscal Year (FY) 2022 – Call for Letters of Interest: IDOE, in partnership with the Indiana Family and Social Services Administration’s (FSSA’s) Division of Mental Health & Addiction (DMHA), is writing a proposal for the competitive Project AWARE FY 2022 Grant released by the Substance Abuse and Mental Health Services Administration (SAMHSA) and funded from the Bipartisan Safer Communities Act. IDOE’s proposal will build off Indiana’s current Project AWARE successes to continue developing sustainable infrastructure for school-based mental health programs and services. The proposal will outline activities to support implementation of school-based mental health related promotion, awareness, prevention, intervention, and resilience activities to ensure that students are aware of and have access to appropriate and effective behavioral health services. IDOE is seeking letters of interest (LOI) from schools and their existing community-based or private mental health providers demonstrating the need for and commitment to project goals. LOIs must be sent to email@example.com by Friday, September 23. Please see this memo for details. Contact firstname.lastname@example.org with any questions.
- Mental Health Awareness videos:
- Mental Health in Schools
- Alltreatment.com is a community-based public-benefit website connecting people to the addiction resources they need.
- Indiana School-Mental Health Provider Memorandum of Understanding
- Effective Collaborations with Community Mental Health Centers for Schools (Indiana Youth Institute, June 2020)
CONTACT TOPIC MANAGER
This is a ‘do it ourselves’ web site. So if you would like to help, or have information or resources to share, please contact us today.
- Aimee on May 22, 2023 @ 11:35:41
- Aimee on May 22, 2023 @ 11:35:38 [Autosave]
- Aimee on May 8, 2023 @ 09:45:35
- Aimee on March 15, 2023 @ 12:42:38
- Aimee on September 18, 2022 @ 19:34:15
- Aimee on September 18, 2022 @ 19:33:17
- Kelly on June 24, 2020 @ 21:08:37
- Kelly on June 24, 2020 @ 21:04:51
- Kelly on March 18, 2019 @ 20:47:23
- Kelly on October 23, 2018 @ 20:26:46
- Mary on August 14, 2018 @ 19:51:34
- Mary on August 14, 2018 @ 19:47:20
- Mary on August 14, 2018 @ 19:19:11
- Mary on August 14, 2018 @ 19:13:14
- Kelly on May 29, 2018 @ 21:11:52
- Kelly on October 4, 2017 @ 16:05:47
- Kelly on November 17, 2016 @ 20:02:45
- Kelly on November 17, 2016 @ 19:58:28
- Kelly on November 17, 2016 @ 19:51:12
- Heather on August 7, 2016 @ 21:23:19
This post was created by MNOP ContentManager on August 7, 2016.

domain: psychology


text:
Disaccharidase Activity Panel
Test in Focus
Mayo Clinic Labs’ new disaccharidase activity panel measures levels of five naturally occurring digestive enzymes to detect deficiencies that affect carbohydrate absorption. The panel, as explained by Mayo Clinic pediatric gastroenterologist Pua Hopson, D.O., in this episode of the "Answers From the Lab" podcast, is the gold standard for diagnosing disaccharidase deficiencies, which can cause chronic conditions like celiac disease.
“Oftentimes when we see these patients who have had chronic illness and have chronic symptoms going on for such a long time, it’s hard to piece together the history,” says Dr. Hopson. “It can be quite complex to tease out ‘A causes B.’ In doing an endoscopy the addition of this test may be really beneficial if you find a deficiency, and sometimes can provide a lot of clarity for your patients’ symptoms.”
Dr. Hopson explains that in the proper clinical setting, disaccharidase activity testing can increase disaccharidase disorder identification by 10% to 20%. “In these cases, you’ll have a higher chance of detecting abnormalities and overall helping your patients clinically.”
Listen to learn more about how disaccharidase activity testing improves patient outcomes by equipping providers with specific details about patients’ malabsorption disorders to confirm diagnosis and inform treatment choices.
Note: Podcasts will not playback on Internet Explorer. Please use an alternative web browser, or listen from your mobile device on a preferred listening app.
Evaluation of patients who present with signs or symptoms suggestive of disaccharidase disorders. This test is not intended for carrier detection.
Cherisse Marcou, Ph.D., and Marissa Ellingson, M.S., CGC, discuss whole exome sequencing (WES) at Mayo Clinic Laboratories. The comprehensive evaluation uses next-generation sequencing to detect for single nucleotide variants, small insertions or deletions, and copy number variants on approximately 20,000 genes, enabling precision answers to accurately diagnose, manage, and treat patients with identified inherited illness.
Alicia Algeciras, Ph.D., describes Mayo Clinic Laboratories’ new blood test to detect NFLC, or neurofilament light chain protein. NFLC is a biomarker for several neurodegenerative conditions. The new assay can determine if a patient’s cognitive decline is due to a neurodegenerative condition or some other, reversible condition — while avoiding the need for more-invasive testing of cerebrospinal fluid.
Paul Jannetto, Ph.D., and Loralie Langman, Ph.D., discuss Mayo Clinic Laboratories' unique approach to urine drug testing for addiction rehabilitation. Designed to guide and monitor therapy, the comprehensive profile tests for the most commonly used substances, including alcohol and nicotine, for a complete picture of a patient’s substance use.


Check out our new website where we will host all future updates and improvements. The Sourceforge site will no longer be maintained and updated.
Project Chronos is an open source time lapse rail. It is a fully features system that offers the same level of control as professional systems costing thousands of dollars. It is also the most accurate time lapse system available capable of making accurate movements 1/125th the width of a human hair. And the best news, is this is 100% open source with all schematics, parts lists, and instructions online and free to use. Feel free to contact us at firstname.lastname@example.org with any questions.
For more information check the home screen and the wiki on this project page, also be sure to check out my Vimeo channel to see the system in actions as well as any news updates.
Like us on Facebook!
- Simple to use interface using the Chronos 2.0 software package makes setup extremely fast and intuitive, even when programming complex movement patterns.
- No dealing with "Inches per minute" and Interval count to determine the number of shots. Rather you just tell Chronos 2.0 how many shots to take and how far to move.
- 36 inches of precision linear travel
- Easy to understand movement patterns ensure predictability.
- 255 levels of LED brightness control.
- Manual position control
- Shot Delay of 0-1000 shots
- Intervalometer 1 second to 1 hour intervals
- Bulb Exposure control 1 second to 1 minute.
- After shot buffer of .1 to .9 seconds
- Number of shots per routine = 30 to 9,999
- Metric to Standard conversion
- HDR trigger to gather 3 frames per interval.
- Shutter signal Pass-through or Block
- Camera Nudge to wake up a camera right before it shoots.
- Distance moved per routine 1-36 inches or 1-91 Centimeters (for a 39 inch (1000mm) rail.
- Symmetrical Velocity ramping 5% - 50% (1% increments)
- Asymmetrical Velocity ramping 5-95% (1 % increments)
- Non ramped movements
- Repeat routine 0-9 times from end
- Repeat routine 0-9 times from beginning
- Run routine then rewind to beginning and wait
- Repeat movement pattern in reverse with symmetrical ramping adjustment
- Repeat movement pattenr in reverse with asymmetrical ramping adjustment
- WSM Shooting display shows Shots taken, Shots remaining, Time elapsed, Time remaining.
- Continuous movement modes, 10 speeds, time weighted by distance selected.
- Master control mode where Chronos provides the timing signal.
- Slave sync mode to enable Chronos to sync to external timers, intervalomters, bulb rampers, or other systems.
- 66 Movement profiles with adjustable delays, shots, buffers, bulb timers, distance to build a virtually endless amount of movement routines.
- Step counting to provide perfect repeatability
- High Strength, capable of lifting a 25lb payload vertically or horizontally, with no need for calibration
- Virtually no setup time, no clips, belts, carts, or motors to attach on site.
- Low maintenance, the Igus rail requires no lubrication and works in extreme enviornments.
- Lightweight at 12lbs for the Rail and control box. (not including tripods or dolly feet)
- Easily syncs up to any system that is capable of triggering a camera via shutter cable, this includes bulb rampers, cameras with built in intervalometers, and other time lapse motion control systems.
- Live Ramp mode enables direct real time control of movement ramping.
- Drift mode give the camera a natural sway.
- Calibration Mode now makes it easier to enable Chronos 2.0 controller to work with other stepper motors.
LicenseAcademic Free License (AFL)
Follow Project Chronos
Rate This ProjectLogin To Rate This Project
Nice work ! Great project.
Chris is a true open-source guy. He's very passionate about the project and was excited to talk to me directly and help me get started with the project. I am making my own rig with Chris mentoring me so that I can help him build out the documentation. He's done a great job of getting me as excited as he is.
I received Chris's serial number 0001 Chronos system about three months ago and can I just say, that this is the most user friendly motion time lapse rig you could ever own. The controlling interface that is supplied is very straight forward. You simply ask it what to do and "Set and forget"! The rig is durable, light and easy to transport. I asked for a longer version slider than advised at 1.4 meters and get fantastic shots. It talks seamlessly to third party devices like 'little bramper' and allows you to concentrate on the more important parts of time lapse like bramping and not have to worry about motion. The shutter closes post exposure, it sends a signal to Chronos and then Chronos moves according to the distant parameters that you have set prior to starting. It is such an easy device to use and I couldn't recommend it more highly. For those worried about freight, I bought the slider and carriage locally in Australia and Chris sent the rest pre fabricated. All I did was follow his instructions and twenty minutes later was in action. This is a very exciting system and after researching many other similar rigs, Chronos is by far the most affordable and easy to use system on the market. Do your self a favour and stop searching anymore, for you have now found what you are looking for. 10 out of 10. Time lapsing enthusiast. CK
I'm still under construction with this project but its all hopefully coming to a close soon! I started this off with a basic understanding of arduino, little to no knowledge on electronics – especially the hardware side and a tight budget to get this constructed with. I started off on a bad start – availability of parts here in the UK is a lot different to what’s available in the US and shipping charges cost the same as a new car for certain parts but I decided I was going to dive in and find alternatives and give it a go. Ordering cheap Chinese parts is a very bad idea. A very bad idea indeed. Some of the parts don’t even work and some are very different to things you have seen before. They don’t send you what you ordered and when you send it back they’ll just post the same thing back with your stickers still on it to track what they are doing. Enough of the waffling. I came into building this with not a lot of idea about how I was going to build it. I gathered parts and started working on it. Chris’s help and support has been the best I have ever received and he has taught me a lot whilst building this rail. Ordering part to save money and because of availability was a battle – but Chris helped modify the schematics and even sent photos to help dummy’s like me get things done and I now have all the electronics working with a cheap Chinese stepper motor, a big easy driver and other strange parts – I wouldn’t have been able to do this without his support and would have given up weeks ago! Not only does this do what it says – but it does a lot more. If I had only knew about this before diving in and backing the timelapse+ this would have done everything anyway! But that doesn’t matter because it has a slave mode to deal with things like bulb rampers and other intervalometers that you might be using. I have discussed many different variations of this with Chris – like the argument of DC vs stepper and belt vs lead screw and he has thought about this design very hard. This is one rail I am looking forward to completing as it has not only been a learning curve for me, but I’m sure Chris will know how to deal with difficult people like me better. His dedication to this project is amazing and his girlfriend must love him a lot! When I have finished my version of this rail I will post pictures and videos and let you all know how it went, if it was worth it and total costs of the build. If it keeps going like it is doing it’s a hell of a lot cheaper than anything out there on the market and has far more features packed into the small box! Overall so far – to sum this up – Chris’s support with anyone who is looking at building this is better than support for anything. And his willing to help is a reason to give this a go and get building a project chronos rail.