text:
PASCAGOULA, Miss., Aug. 06, 2019 (GLOBE NEWSWIRE) -- Huntington Ingalls Industries (NYSE:HII) hosted a graduation ceremony on Saturday for the company’s apprenticeship program at Ingalls Shipbuilding. Nine different crafts were represented among the 159 graduates of the 2019 class. ...
PASCAGOULA, Miss., Aug. 14, 2019 (GLOBE NEWSWIRE) -- Huntington Ingalls Industries (NYSE:HII) announced today leadership changes at its Ingalls Shipbuilding and Newport...Nasdaq Globe Newswire 2019-08-14
NEWPORT NEWS, Va., Aug. 08, 2019 (GLOBE NEWSWIRE) -- Huntington Ingalls Industries (NYSE: HII) announced today that the Disabled American Veterans (DAV) named HII as its...Dothan Eagle 2019-08-08
ALACHUA, Fla., Aug. 20, 2019 /PRNewswire/ -- NCCER recently released the following curricula: Project Management; Pipefitting Levels 1 – 4; Maritime Electrical Levels 1 –...The Philadelphia Tribune 2019-08-20
NEWPORT NEWS, Va., Aug. 08, 2019 (GLOBE NEWSWIRE) -- Huntington Ingalls Industries (NYSE: HII) announced today that the Disabled American Veterans (DAV) named HII as its...Nasdaq Globe Newswire 2019-08-08
Popular News Stories
Amazon rainforest fires: Jair Bolsonaro sends Brazilian army to put out huge blaze as G7 leaders hold emergency talks
Russia’s Vladimir Putin vows ‘reciprocal response’ to US cruise missile test
South China Morning Post
Published on: 08 August 2019 Do you have graduating apprentices this year? Don't miss the annual British Marine Apprenticeship Graduation, which takes place at Southampton International Boat Show, powered by Borrow A Boat, on Tuesday 17 September 2019 at 10:30 in the British Marine Members & Exhibitors Lounge. All graduating apprentices from current British Marine member...Public Technologies 2019-08-08
HUNTINGTON, W.Va. (AP) — For 24 now-graduated high school seniors — and the staff who pushed them — the night of Aug. 15 came better late than never. It didn't have the elbow-to-elbow crowds or the scattering of air horn bursts like the standard Cabell Midland or Huntington High graduations, but Cabell County's first ever Summer School Graduation was just as poignant, if not...San Francisco Chronicle 2019-08-17
High School Students Earn Aircraft Manufacturing Pre-Apprenticeship Accreditation Stratford, Conn., Aug. 13, 2019 - At the closing ceremony for the Teamsters/Sikorsky Career Pathways Program, Teamsters Local 1150 in partnership with Sikorsky, a Lockheed Martin Company (NYSE: LMT), Connecticut State Department of Education and Connecticut Department of Labor, announced the...Public Technologies 2019-08-13
New Trump Labor Department apprenticeship rules, opening training for building trades jobs to cut-rate non-union firms and their bosses – while threatening quality training and building standards – are “like the fox guarding the henhouse,” a veteran construction union apprenticeship trainer says. But workers and unions concerned over the Trump DOL scheme don’t have much time...People's World 2019-08-15
Government of Canada helps African Nova Scotians prepare for high-demand and well-paying jobs in the ...
DARTMOUTH, NS, /CNW/ - Canada's changing economy and investments in infrastructure make skills training critical to our future. To keep our economy strong and growing, Canadians will need the right skills to fill in-demand and well-paying jobs. The Government of Canada is taking steps to encourage key groups facing barriers to explore careers in the trades. Today, Darren...Canada Newswire 2019-08-15
NEWPORT NEWS, Va (NNS) -- Sailors assigned to USS Gerald R. Ford's (CVN 78) Reactor Department and Huntington Ingalls Industries-Newport News Shipbuilding (HII-NNS) technicians recently completed a production milestone by reaching the propulsion plant completion date (PPCD), July 22. After more than 12 months of maintenance and repairs, the Navy accepted re-delivery of the...Public Technologies 2019-08-12


Video Chat with a Photography Expert - Live
- For Profoto A-Series Flashes
- Charge Time: 80 Minutes
- UN-Certified for Air Travel
Able to last for multiple times longer than conventional AA batteries, the Profoto A-Series Battery Mk II will keep your flashes powered up. This can produce up to 450 full-power flashes on a single charge (depending on the A-series flash model). Additionally, it is UN-certified for air travel.


Niagara County Community College plans to leave its location in the county-owned Trott Access Center in Niagara Falls next year.
NCCC President James P. Klyczek said the college is negotiating for space in a building near the Seneca Niagara Casino, though not on land controlled by the Seneca Nation. He would not identify the likely new location.
"The college seems to have independent authority to decide their leases," County Manager Gregory D. Lewis said.
NCCC has been in the former Trott Vocational High School at 11th Street and Packard Road almost since the county bought the building in the late 1980s. "One of the primary issues is accessibility for our clients and students," Klyczek said, adding that he wants to be in a location "perceived as safe."
"Back when we bought Trott, I opposed it, but they said they needed it for the students who couldn't get to the (Sanborn) campus. Now we're saying we don't need the Trott building for the college," groused Legislator Gerald E. Meal, R-Royalton.
Klyczek said the college is willing to stay at Trott through May 31, and the Legislature's Public Works Committee reluctantly approved that action. NCCC will pay $178,548, or $12.55 per square foot for 14,227 square feet. The state reimburses NCCC for about 21 percent of its rent.
Klyczek noted that past leases have allowed either NCCC or the county to terminate the deal with 90 days' notice. He said the college will pay the moving expenses.
"We want to move out of there, but we don't want to cut anybody short," Klyczek said. "The county wants us in there as long as possible until they can find someone else (to lease the space)."
Though the county renovated Building G on the Sanborn campus two years ago -- part of a $4.8 million construction package -- for the culinary arts program, Klyczek said, the college will move its hospitality and culinary arts programs to the new downtown Niagara Falls location, as well as all of activities from Trott.
Those include the licensed practical nursing and dental hygienist programs and an assortment of grant-funded job skills programs.
Public Works Commissioner Kevin P. O'Brien said that there has been talk of moving the Probation Department's Niagara Falls operations to Trott from the Angelo A. DelSignore Civic Building at Third Street and Cedar Avenue. However, as an agency in the main county budget, the Probation Department would not pay rent.
Lewis said Trott's long corridors, halls and lobbies constitute a lot of wasted space in the 98,000-square-foot building. He has proposed constructing two new county office campuses, one in the east and one in the west, at a cost of $50 million.


text:
Your list is empty.
Save musicians, entertainers, speakers, and services, and they’ll appear here.
Complete the form to receive FREE no-obligation quotes from World & Culturals in Cliffside Park.
New York City, NY
8 miles from Cliffside Park
super professional, super entertainer, and terribly cute, love the music and songs choice, great…
A great entertainer, very friendly and flexible. Mr.Crichlow was early and quickly set up. This…
Great team and performance! Whole band came from New York full of energy! Amazing night at the…
5 miles from Cliffside Park
Hola! I am a NYC certified Spanish teacher with experience with students from Kindergarten through 12th grade.…
We hired Taikoza for elementary school assemblies. They were very professional to deal with in…
I offer a quality and authentic experience of Indian classical music.
¡Retumba! (Resound!) brings vibrant interactive performances that are musically soulful, passionate, visually…
Kk Tafari born Kelvin Harrison in Kingston Ja in brought up in a Rastafari home with 3 other siblings they had…
After a successful outdoor performance several years ago by a duo from Didge Project for our…

domain: artistic


text:
Molecular Mechanisms Involved in Inflammation and Insulin Resistance in Chronic Diseases and Possible InterventionsView this Special Issue
Research Article | Open Access
Guangyin Zhang, Ming Li, Liangjun Li, Yingzhi Xu, Peng Li, Cui Yang, Yanan Zhou, Junping Zhang, "The Immunologic Injury Composite with Balloon Injury Leads to Dyslipidemia: A Robust Rabbit Model of Human Atherosclerosis and Vulnerable Plaque", BioMed Research International, vol. 2012, Article ID 249129, 11 pages, 2012. https://doi.org/10.1155/2012/249129
The Immunologic Injury Composite with Balloon Injury Leads to Dyslipidemia: A Robust Rabbit Model of Human Atherosclerosis and Vulnerable Plaque
Atherosclerosis is a condition in which a lipid deposition, thrombus formation, immune cell infiltration, and a chronic inflammatory response, but its systemic study has been hampered by the lack of suitable animal models, especially in herbalism fields. We have tried to perform a perfect animal model that completely replicates the stages of human atherosclerosis. This is the first combined study about the immunologic injury and balloon injury based on the cholesterol diet. In this study, we developed a modified protocol of the white rabbit model that could represent a novel approach to studying human atherosclerosis and vulnerable plaque.
Atherosclerosis is the most common pathological process that leads to cardiovascular diseases (CVDs), a disease of large- and medium-sized arteries, that is characterized by a formation of atherosclerotic plaques consisting of necrotic cores, calcified regions, accumulated modified lipids, inflamed smooth muscle cells (SMCs), endothelial cells (ECs), leukocytes, and foam cells [1, 2]. Several features of atherosclerotic plaques illustrate that atherosclerosis is a complex disease, and many components of the vascular, metabolic, and immune systems are involved in this process . Although dyslipidemia like higher low-density lipoprotein (LDL) or higher triglyceride (TC) remains the most important risk factor for atherosclerosis, immune and inflammatory mechanisms of atherosclerosis have gained tremendous interest in the past 20 years [4, 5].
The area of atherosclerotic plaques research is day by day expanding and the animal models play a very crucial role in this onward journey. An animal model is a nonhuman animal that has a disease or injury that is similar to a human condition . They are due to focal accumulation of cells within the intima of the artery , both intra- and extracellular lipids , fibrous tissues , complex proteoglycans, and mineral blood and blood products . Even though there is no one perfect animal model that completely replicates the stages of human atherosclerosis, cholesterol feeding and mechanical endothelial injury are two common features shared by most models of atherosclerosis [11, 12]. Several characteristics of the rabbit make it an excellent model for the study of atherosclerosis. Previous experimental models for studying this vessel disease consist of rabbits and rats undergoing cholesterol feeding and mechanical endothelial injury . We have built a model based on rabbit that including cholesterol feeding, immunologic injury, and mechanical endothelial injury. Studies in these models have primarily focused on the rules of changes in blood lipids and the morphology and inflammation of the arterial walls .
The aim of this experimental study was to evaluate the applicability of a modified white rabbit model that were injured with immunologic and balloon base on the cholesterol diet. We evaluated the model from cholesterol metabolism, immune and inflammatory mechanisms and impaired level of reactive oxygen species. The model that we characterize here would be useful for studying the entire process of human atherosclerosis from dysfunction of cholesterol metabolism to the formation of atherosclerotic plaques.
2. Materials and Methods
2.1. Animals and Experimental Design
All animal experiments were performed with the approval of the Animal Care Committee of the Tianjin University of Traditional Chinese Medicine and complied with the Animal Management Rule of the Ministry of Public Health, People’s Republic of China (Documentation 55, 2001). Twenty-four, adult (3 months old, kg), male, Japanese white rabbits were purchased from Vital River Lab Animal Technology Co., Ltd. (Beijing, China) and were housed in an animal room maintained at °C with 40% to 60% RH and a light period from 8:00 to 20:00 in the Laboratory Animal Center of Tianjin university of TCM. The rabbits were divided randomly into two groups, normal-diet group (normal, ) was fed the rabbit standard diet (100 g per rabbit per day) and experimental model group (CIB, ) were fed an atherogenic diet (1% cholesterol, 5% yolk, 5% lard, and 89% standard diet). All the animals had free access to water. A scheme of the design of the atherosclerotic model study is shown in Figure 1.
2.2. Immunologic Injury and Balloon Injury
Initially, all experiment rabbits were fed with cholesterol diet (Yingbo, Tianjin, China) 2 weeks prior to injecting solcoseryl albumin (Sangon, Shanghai, China, 250 mg/kg) from the marginal ear vein and 4 weeks after balloon injury of the abdominal aorta, followed by 6 weeks of cholesterol chow diet constantly. All rabbits underwent balloon-induced endothelial injury in the abdominal aorta after being anesthetized with 3% pentobarbital sodium salt (Sigma-Aldrich P3761, US, 30 mg/kg body weight, iv), and balloon injury of the abdominal aortic wall was performed using a 4F Fogarty catheter (Shangyikangge, Shanghai, China) introduced through a right femoral artery cutdown. After the catheter was advanced to the diaphragm, the balloon was inflated and the catheter was gently retracted toward the iliofemoral artery. This was repeated three times. The method was demonstrated in previous reports [15, 16].
2.3. Biochemical Parameters
Animals were bled from the marginal ear vein at baseline at the end of weeks 3, 6, and 10 (3 mL each time). Blood samples were centrifuged at 2 000 g for 20 minutes to obtain serum and plasma. The serum was used for biomarkers assay.
Collected serum was analyzed in an automatic blood chemical analyzer (Humalyzer 2000, Nairobi, Kenya), and the serum concentrations of total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) were obtained (enzyme-colorimetric method). At the same time, serum levels of superoxide dismutase (SOD), malondialdehyde (MDA), and nitric oxide (NO) were estimated by enzyme colorimetric method with kits from, Jiancheng Bioengineering Institute (Nanjing, China), and serum levels of monocyte chemoattractant protein-1 (MCP-1), tumor necrosis factor-α (TNF-α), and oxidized LDL cholesterol (ox-LDL) were measured by use of enzyme-linked immunosorbent assay (ELISA) kits (Rapid Bio, California, US).
2.4. Tissue Preparation
The experiment was continued till 10 weeks. After euthanasia of the animals by intravenous injection of pentobarbital (Sigma-Aldrich P3761, US, 50 mg/kg body weight, iv) at the end of weeks 10, the blood sample was taken via the marginal ear vein. The aorta from the aortic valve to the femoral bifurcation tissue of animals was removed. The abdominal aortic tissue was collected for histological study and remainders stored at −80°C for other studies.
The abdominal aortas from the rabbits were immediately excised and cut into 10 serial 2.5 mm sections, with alternative sections embedded in paraffin and catalogued. The tissue sections (6 μm thick) were cut from paraffin-embedded blocks on a microtome and mounted from warm water (40°C) onto adhesive microscope slides. Sections were allowed to dry overnight at room temperature and for later general histological staining, as described previously [17, 18].
2.5. Histological and Morphometric Evaluation
2.5.1. Identification of Atherosclerotic Plaques
The fatty streak lesions of the thoracic aorta in each group were easily identified by staining with Sudan III (Sangon, Shanghai, China), as described above . After formalin fixation of the arteries, paraffin blocks were prepared by the following routine histological procedures. The tissue sections were obtained from the prepared paraffin blocks and were stained with hematoxylin and eosin (H&E). All slides were examined by Olympus BX 40 Light Microscope (Olympus Corporation, Tokyo, Japan), and Champion HMIAS-2000 Image Analysis System (Wuhan Champion Image Technology Co., Ltd, Hubei, China) was used for image processing. The luminal intimal and medial cross-sectional areas of the arteries were measured and the index defined as intimal/medial area ratio was calculated from these measurements. The fibrous cap thickness was measured by drawing lines perpendicular to the lumen at three different locations of the fibrous cap on sections stained with the measurement as well, and the mean value was calculated. The other segment was used for cryosections and cut into 6 μm thick sections for Masson’s trichromatic and Oil Red O staining, and the methods used here were demonstrated in previous reports [20, 21].
2.5.2. Immunohistochemistry in Abdominal Aortas Lesions
Immunohistochemical staining involved several standard techniques as described previously . In brief, all tissue sections were rinsed with PBS at pH 7.4; in order to block endogenous peroxidase activity; the sections were incubated in 0.3% H2O2 for 30 min, and then washed with PBS. Followed by incubating in secondary antibody for 30 minutes at 37°C. The secondary antibody and all subsequent reagents were diluted in PBS containing 0.1% bovine serum albumin; 200 μL of the diluted solution was added to each slide and incubated in a moisture chamber. Immunohisto-chemical staining was visualized by use of a diaminobenzidine kit (TBD Science, Tianjin, China) according to the manufacturer’s instructions. The primary antibodies included α-smooth muscle cell actin (Thermo Fisher Scientific, US), anti-CD68 polyclonal antibody, anti-CD31 polyclonal antibody (R&D Systems, Minneapolis, MN, USA) matrix metalloproteinase-9 antibody (Abcam, Cambridge, UK), vascular endothelial growth factor antibody (Santa Cruz Biotechnology, CA, USA), and NF-kB P65 subunit antibody (Thermo Fisher Scientific, USA).
3. Statistical Analysis
The Statistical Package for the Social Sciences (SPSS) 11.0 was used for the analysis. Results are given as mean ± SD. Data were analyzed statistically using one-way ANOVA test followed by LSD posttest, and pairwise multiple comparisons were performed using LSD posttest. In all instances, P value less than 0.05 or 0.01 was considered significant.
4.1. Design of the Animal Experiments
During the experiment, six rabbits in the CIB group and two rabbits in the normal group died of anesthesia overdose or diarrhea. Data was available for analysis for 6 rabbits in the normal group and 10 for CIB group. The animal body weight was not statistically significant in the CIB group compared with the normal group in week 0, 3, 6, 10, as shown in Table 1. We found that the animal body weight of CIB group was slightly decreased at the end of the sixth weekend it was probably due more to diet reduction after surgery.
Data are given as the mean ± SD. No significant difference was found between the normal group and the CIB group.|
4.2. Cholesterol Levels
Table 2 shows lipid profile of serum in two groups; the levels of serum TC, TG, LDL-C, and HDL-C were elevated in general. Serum TC levels in the CIB group were higher than those in the control group at 3rd, 6th, and 10th weekend, respectively (). Compared with the normal group, serum TG levels were increased in the CIB group at the 3rd weekend (), and the levels significantly increased at the 10th weekend (). However, which levels in CIB group not increased like TC than in the control group at the 6th weekend. Under a high cholesterol diet, the levels of the serum LDL-C of the rabbits were elevated as well. The serum LDL-C levels in the CIB group were higher than those in the normal group at the 3rd, 6th weeks, respectively, and showed a significant difference at the 10th weekend. Serum HDL-C levels kept the same trend in both groups.
|TC: total cholesterol; TG: triglyceride; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol. Data are expressed as mean ± SD, *; ** compared with normal.|
4.3. Histological and Morphometric Evaluation
4.3.1. Identification of Atherosclerotic Plaques
The fatty streak lesions of the aorta in two groups were easily identified by staining with Sudan III or by macroscopic observation. Broad and fused fatty streak lesions were easily found in CIB group that was stained most seriously, almost the whole aorta was red, whereas no atherosclerotic plaques were observed in the normal group (Figures 2(a) and 2(b)). The percent area of the atherosclerotic plaques was measured in both groups as shown in Figure 2(c).
The fibrous cap thickness was measured by drawing lines perpendicular to the lumen at three different locations of the fibrous cap on sections. When compared with that of the normal group, fibrous cap thickness was significantly increased in CIB group (.96 μm, Figure 3(a)), and the ratios of fibrous cap and intima media thickness were calculated (, Figure 3(b)).
The atherosclerotic plaque content of SMCs was lower in the normal group while the content of lipid core area was lower in the CIB group. But CD68 and collagen content of the plaques were higher in the CIB group; as a result, the vulnerability index in the normal group was lower than that in the CIB group (Figure 4(a)). The ratio of lipid core area and plaque area, and ratio of plaque area and intima area were calculated as well (Figure 4(b)).
There was no detectable change in the size of the medial thickness of aortic arch thoracic aorta and abdominal aorta, but the intima thickness of the aorta and the ratio of intima and media in CIB group was the highest. The index of endometrial hyperplasia was remarkably different between the two groups (Figure 5).
4.4. Immunohistochemical Inflammatory Markers and Others
Immunologic injury and high cholesterol control induced a significant increase in systemic inflammatory response in CIB group. NF-κB is a key factor that regulates the expression of many genes involved in the pathophysiology of tissue inflammation. In CIB group, NF-κB was increased significantly compared to the normal diet group on the basis of atherosclerotic arteries sections, and strong MMP-9 positive staining was also observed And CD31 and VEGF have the same trend with MMP-9 (Figure 6).
4.5. Oxidative Factors
Serum levels of ox-LDL were elevated at week 3 and 6 in the CIB group, but compared to the week 6, it has a mild reduction. The levels of NO decreased after the immunologic injury, however, at week 10, which was significantly higher in CIB group than in the control group. Serum level of SOD was reduced by the immunologic injury due to the cholesterol diet, but it was elevated at week 6 maybe because the intima was destroyed by balloon injury. Compared to the control group, MDA was increased uniformly at week 3, 6, and 10. In CIB group, MCP-1 was increased significantly compared to the normal diet group at the end of the third week, whereas there was no obvious differences in week 6. The levels of IL-1 have slightly decreased at week 6 compared to week 3; TNF-α kept a same trend with MCP-1 (Figure 7).
Atherosclerosis is characterized by lipid accumulation in the vessel wall, inflammation, oxidative stress, and immunologic injury . There is no perfect animal model that completely replicates all stages of human atherosclerosis, yet the model may be a promising entity in exploring the aetiopathogenesis and regression of atherosclerosis [24, 25]. In this study, we developed a modified protocol of the JW rabbit that reproduced features of atherothrombosis observed in humans. All the experimental rabbits have been injected with foreign protein, remodeled mechanical endothelial injury, and undergone cholesterol feeding. Histological features of the aorta and the levels of cholesterol, inflammation, and oxidative stress were measured and evaluated to the robust animal models. The key finding of our study is that the rabbit and human atherosclerotic plaques have remarkable similarities. In addition, several novel ideas which enhance our understanding of the mechanisms of human atherosclerotic stages were also introduced by this study.
Cholesterol feeding and mechanical endothelial injury are two common features shared by most models of atherosclerosis , but the occurrence of coronary or aortic atherosclerosis in immunopathology factors probably play a major role . We retained the procedure of cholesterol diet for longer durations, which leads to lipid toxicity. And the balloon injury could accelerate cholesterol deposition on the arterial wall and injury of the foreign protein maybe make inflammation and oxidative stress of atherosclerosis more serious [28, 29].
At the beginning of the experiment, blood lipid distributions of all animals were evaluated and there was no significant difference between the two groups. The high-cholesterol diet containing egg yolk and lard oil is very similar to the characteristics of human diet. We chose to perform immunologic injury at two weeks after initiating the high-cholesterol diet, for the immunopathology factors may increase the severity of the local per oxidative damage and inflammatory response . The experimental animals have been injured with balloon at four weeks after initiating the high-cholesterol diet so that endothelial damage occurred in a setting of increased disorders of lipid metabolism, which could further accelerate plaque formation . What makes me surprised was that the serum cholesterol levels were significantly higher in CIB rabbits than in normal diet rabbits at the end of week 3, but not significantly increased after balloon injury comparing to the week 3. It is becoming increasingly evidential that immunologic injury to the system is probably a primary causative factor in atherosclerosis.
Plaque vulnerability is characterized by a large lipid-rich atherosclerotic core, a thin fibrous cap, and infiltration by inflammatory cells, such as macrophages [32, 33]. Compared with intact caps, the ruptured ones usually are thinner and contain less collagen, have fewer SMCs, and are heavily infiltrated by macrophage foam cells. Atherosclerosis plaques with its constituents, including lipid core structure, proliferating SMCs, and collagen fibers, was observed in the experiment described above. The observations of plaque constituents suggested that there were a higher intima-to-media thickness ratio and intimal hyperplasia index and were confirmed by previous reports of high macrophage density in areas of plaque rupture [34, 35]. This correlation proves that the plaque which is characterized by a large lipid-rich athermanous core and a thin fibrous cap is more inflammatory and vulnerable. The experiment also showed that the pathology of the abdominal aortic was most serious, followed by the thoracic aorta and aortic arch. The intima thickness was significantly higher in CIB rabbits than in normal diet rabbits, but not significant different in media thickness between two groups.
Inflammation plays a pivotal role in all stages of thermogenesis, from foam cell to plaque formation to rupture and ultimately to thrombosis, so the inflammatory response in animal blood was evaluated [36, 37]. In this regard, the data suggested that the presence of immunologic injury in high-cholesterol diet rabbits results in a more vulnerable vessel wall at the site of the endothelial lesion. IL-6, MCP-1, and TNF-α are three critical mediators of the systemic effects in inflammatory endothelial lesion, and they are also associated with the precipitation of atherosclerotic events. As expected, serum levels of IL-6, MCP-1, and TNF-α increased in the CIB group at week 3, 6, and 10 compared with the control group. The previous studies have demonstrated that MCP-1 expression occurs in the arterial wall in response to hypercholesterolemia in rabbits. Oxidized LDL also induces local vascular cells to produce MCP-1, which causes monocyte recruitment and promotes the release of lipids and liposomal enzymes into the extracellular space, thereby enhancing the progression of the atherosclerotic lesion .
It is now recognized that atherosclerotic plaques are characterized not only by the presence of inflammatory reactions but also by oxidative stress. Oxidative stress induces inflammatory responses causing damage to the vasculature and may play an important role in the development of many diseases including atherosclerosis. It also causes direct damage to proteins or leads to chemical modification of amino acids in proteins. This increases the protein content in carbonyls, which then serve as biomarkers of general oxidative stress. The level of per oxidative damage has also been evaluated in this experiment. Oxidized LDL is highly cytotoxic and may promote the development of atherosclerosis by several mechanisms. MDA is a main byproduct of lipid peroxidation; lipid peroxidation is evaluated by levels of circulating MDA in our research. MDA production increases in CIB group early at week 3, confirming previous reports that an increased formation of lipid peroxidation products occurs. NO is a powerful regulator of vascular function, and it appears that abnormalities in the production or actions of NO lead to endothelial dysfunction and abnormal vascular remodeling. In our experiment, the serum NO level in the CIB group was higher than those in the normal group at the 3rd, but there was a slightly decreased after treating with balloon angioplasty in the 4th week, respectively, and it showed a significant difference at the 10th weekend, which may be that the function of blood vessel endothelium of rabbit was recovered after injuring with balloon angioplasty in the 4th week.
In conclusion, CIB rabbit, a novel robust model of atherosclerotic plaques, not only has the disorders of lipid metabolism but also carries the metabolic syndrome, which partially caused by immunologic derangement. The pathophysiology of the CIB rabbit coincides well with the current concept of metabolic syndrome, which contends that lipid toxicity accumulation is the fundamental disorder and that inflammation, oxidative stress, and lipid metabolism disorders are intimately related to the evolution of atherosclerosis. As the metabolic pattern for rabbits resembles that in humans, CIB rabbits have superior clinical usefulness compared with other animal models, especially in herbalism fields.
This work was supported by the State Key Program of the National Natural Science Foundation of China (no. 30973731; 30901905).
- E. Galkina and K. Ley, “Immune and inflammatory mechanisms of atherosclerosis,” Annual Review of Immunology, vol. 27, pp. 165–197, 2009.
- A. C. Doran, N. Meller, and C. A. McNamara, “Role of smooth muscle cells in the initiation and early progression of atherosclerosis,” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 28, no. 5, pp. 812–819, 2008.
- C. Vinegoni, I. Botnaru, E. Aikawa et al., “Indocyanine green enables near-infrared fluorescence imaging of lipid-rich, inflamed atherosclerotic plaques,” Science Translational Medicine, vol. 3, no. 84, Article ID 84ra45, 2011.
- R. Ross, “Atherosclerosis—an inflammatory disease,” The New England Journal of Medicine, vol. 340, no. 2, pp. 115–126, 1999.
- G. K. Hansson and P. Libby, “The immune response in atherosclerosis: a double-edged sword,” Nature Reviews Immunology, vol. 6, no. 7, pp. 508–519, 2006.
- M. Joner, G. Nakazawa, C. Bonsignore et al., “Histopathologic evaluation of nitinol self-expanding stents in an animal model of advanced atherosclerotic lesions,” EuroIntervention, vol. 5, no. 6, pp. 737–744, 2010.
- M. Sigovan, L. Boussel, A. Sulaiman et al., “Rapid-clearance iron nanoparticles for inflammation imaging of atherosclerotic plaque: initial experience in animal model,” Radiology, vol. 252, no. 2, pp. 401–409, 2009.
- A. A. Gupte, J. Z. Liu, Y. Ren et al., “Rosiglitazone attenuates age- and diet-associated nonalcoholic steatohepatitis in male low-density lipoprotein receptor knockout mice,” Hepatology, vol. 52, no. 6, pp. 2001–2011, 2010.
- J. Masuda and R. Ross, “Atherogenesis during low level hypercholesterolemia in the nonhuman primate. II. Fatty streak conversion to fibrous plaque,” Arteriosclerosis, vol. 10, no. 2, pp. 178–187, 1990.
- D. E. Karangelis, I. Kanakis, A. P. Asimakopoulou et al., “Glycosaminoglycans as key molecules in atherosclerosis: the role of versican and hyaluronan,” Current Medicinal Chemistry, vol. 17, no. 33, pp. 4018–4026, 2010.
- N. S. van Ditzhuijzen, M. van den Heuvel, O. Sorop et al., “Invasive coronary imaging in animal models of atherosclerosis,” Netherlands Heart Journal, vol. 19, no. 10, pp. 442–446, 2011.
- J. Nanobashvili, M. Prager, A. Jozkowicz et al., “Positive effect of treatment with synthetic steroid hormone Tibolon on intimal hyperplasia and restenosis after experimental endothelial injury of rabbit carotid artery,” European Surgical Research, vol. 36, no. 2, pp. 74–82, 2004.
- M. Ragni, P. Golino, P. Cirillo et al., “Endogenous tissue factor pathway inhibitor modulates thrombus formation in an in vivo model of rabbit carotid artery stenosis and endothelial injury,” Circulation, vol. 102, no. 1, pp. 113–117, 2000.
- O. Lazoura, D. Zacharoulis, T. Kanavou et al., “A novel experimental animal model of arterial stenosis based on endovascular radiofrequency energy application,” Journal of Investigative Surgery, vol. 24, no. 3, pp. 123–128, 2011.
- L. Zhang, Y. Liu, X. T. Lu et al., “Traditional Chinese medication Tongxinluo dose-dependently enhances stability of vulnerable plaques: a comparison with a high-dose simvastatin therapy,” American Journal of Physiology, vol. 297, no. 6, pp. H2004–H2014, 2009.
- S. Brizzola, M. De Eguileor, T. Brevini et al., “Morphologic features of biocompatibility and neoangiogenesis onto a biodegradable tracheal prosthesis in an animal model,” Interactive Cardiovascular and Thoracic Surgery, vol. 8, no. 6, pp. 610–614, 2009.
- F. Acocella, S. Brizzola, C. Valtolina et al., “Prefabricated tracheal prosthesis with partial biodegradable materials: a surgical and tissue engineering evaluation in vivo,” Journal of Biomaterials Science, Polymer Edition, vol. 18, no. 5, pp. 579–594, 2007.
- C. Calcagno, J. C. Cornily, F. Hyafil et al., “Detection of neovessels in atherosclerotic plaques of rabbits using dynamic contrast enhanced MRI and 18F-FDG PET,” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 28, no. 7, pp. 1311–1317, 2008.
- G. Rega, C. Kaun, S. Demyanets et al., “Vascular endothelial growth factor is induced by the inflammatory cytokines interleukin- 6 and oncostatin m in human adipose tissue in vitro and in murine adipose tissue in vivo,” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 27, no. 7, pp. 1587–1595, 2007.
- M. Kawasaki, A. Hattori, Y. Ishihara et al., “Tissue characterization of coronary plaques and assessment of thickness of fibrous cap using integrated backscatter intravascular ultrasound—comparison with histology and optical coherence tomography,” Circulation Journal, vol. 74, no. 12, pp. 2641–2648, 2010.
- Y. Qiao, I. Ronen, J. Viereck, F. L. Ruberg, and J. A. Hamilton, “Identification of atherosclerotic lipid deposits by diffusion-weighted imaging,” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 27, no. 6, pp. 1440–1446, 2007.
- H. Liu, X. Wang, K. B. Tan et al., “Molecular imaging of vulnerable plaques in rabbits using contrast-enhanced ultrasound targeting to vascular endothelial growth factor receptor-2,” Journal of Clinical Ultrasound, vol. 39, no. 2, pp. 83–90, 2011.
- J. A. Leopold and J. Loscalzo, “Oxidative risk for atherothrombotic cardiovascular disease,” Free Radical Biology and Medicine, vol. 47, no. 12, pp. 1673–1706, 2009.
- T. Shimizu, K. Nakai, Y. Morimoto et al., “Simple rabbit model of vulnerable atherosclerotic plaque,” Neurologia Medico-Chirurgica, vol. 49, no. 8, pp. 327–332, 2009.
- L. Xiangdong, L. Yuanwu, Z. Hua, R. Liming, L. Qiuyan, and L. Ning, “Animal models for the atherosclerosis research: a review,” Protein and Cell, vol. 2, no. 3, pp. 189–201, 2011.
- A. Matsuda, Y. Suzuki, K. Kondo, Y. Ikeda, and K. Umemura, “Hypercholesterolemia induces regression in neointimal thickening due to apoptosis of vascular smooth muscle cells in the hamster endothelial injury model,” Cardiovascular Research, vol. 53, no. 2, pp. 512–523, 2002.
- P. Krebs, E. Scandella, B. Bolinger, D. Engeler, S. Miller, and B. Ludewig, “Chronic immune reactivity against persisting microbial antigen in the vasculature exacerbates atherosclerotic lesion formation,” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 27, no. 10, pp. 2206–2213, 2007.
- A. A. Amran, Z. Zakaria, F. Othman, S. Das, S. Raj L, and N. M. M. Nordin, “Aqueous extract of Piper sarmentosum decreases atherosclerotic lesions in high cholesterolemic experimental rabbits,” Lipids in Health and Disease, vol. 9, article 44, 2010.
- F. Hakimoǧlu, G. Kizil, Z. Kanay, M. Kizil, and H. Isi, “The effect of ethanol extract of Hypericum lysimachioides on lipid profile in hypercholesterolemic rabbits and its in vitro antioxidant activity,” Atherosclerosis, vol. 192, no. 1, pp. 113–122, 2007.
- M. L. Kohut, Y. J. Sim, S. Yu, K. J. Yoon, and C. M. Loiacono, “Chronic exercise reduces illness severity, decreases viral load, and results in greater anti-inflammatory effects than acute exercise during influenza infection,” Journal of Infectious Diseases, vol. 200, no. 9, pp. 1434–1442, 2009.
- X. Li, J. R. Du, W. D. Wang et al., “Experimental study of effect of tanshinone on artery restenosis in rat carotid injury model,” Zhongguo Zhongyao Zazhi, vol. 31, no. 7, pp. 580–584, 2006.
- T. Temma, Y. Ogawa, Y. Kuge et al., “Tissue factor detection for selectively discriminating unstable plaques in an atherosclerotic rabbit model,” Journal of Nuclear Medicine, vol. 51, no. 12, pp. 1979–1986, 2010.
- H. J. Park, J. Y. Baek, W. S. Shin et al., “Soluble receptor of advanced glycated endproducts is associated with plaque vulnerability in patients with acute myocardial infarction,” Circulation Journal, vol. 75, no. 7, pp. 1685–1690, 2011.
- T. Gordon, W. P. Castelli, and M. C. Hjortland, “High density lipoprotein as a protective factor against coronary heart disease. The Framingham study,” American Journal of Medicine, vol. 62, no. 5, pp. 707–714, 1977.
- H. Chen, J. Cai, X. Zhao et al., “Localized measurement of atherosclerotic plaque inflammatory burden with dynamic contrast-enhanced MRI,” Magnetic Resonance in Medicine, vol. 64, no. 2, pp. 567–573, 2010.
- R Ross, “Atherosclerosis—an inflammatory disease,” The New England Journal of Medicine, vol. 340, no. 2, pp. 115–126, 1999.
- J. Fan and T. Watanabe, “Inflammatory reactions in the pathogenesis of atherosclerosis,” Journal of Atherosclerosis and Thrombosis, vol. 10, no. 2, pp. 63–71, 2003.
- L. Zhong, W. Q. Chen, X. P. Ji et al., “Dominant-negative mutation of monocyte chemoattractant protein-1 prevents vulnerable plaques from rupture in rabbits independent of serum lipid levels,” Journal of Cellular and Molecular Medicine, vol. 12, no. 6, pp. 2362–2371, 2008.
Copyright © 2012 Guangyin Zhang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

domain: biology


Documentary Films on The D-Word
AGE UP (2015)
Seattle youth are learning how to become tomorrow's leaders while playing Ultimate Frisbee.
Grief in the 21st Century: The Search for Compassion, Community and Connection.
The first major documentary exploring the life and work of French iconoclast Claude Lanzmann.
Produced by CLAIRE MISSANELLI
BLAST! is a spectacular and suspenseful story of space exploration.
Forever Wild (2013)
The inspiring story of Alabama’s Forever Wild Land Trust and the collaboration it took to create.


text:
Vingroup — a Vietnamese conglomerate with interests in property development, health care, education, and retail — and Cornell announced the six-and-a-half year consulting deal earlier this month. The university will include schools of business, hospitality real estate, engineering, and more.
“We didn’t see [global TNE] in Vietnam, so… this is a place where we can take the lead role”
“We see that [Vietnam is] a growing part of the world economy, growing fast, and none of the major universities, honestly, from the West are there,” said Rohit Verma, dean of external relations for Cornell’s SC Johnson College of Business.
VinUniversity will be a domestic Vietnamese institution, with Cornell’s role in the project strictly advisory. Cornell will advise on infrastructure development, campus services, curriculum, and faculty hiring, Verma said.
Industry observers have said that Vietnam would continue to send growing numbers of students abroad until a local alternative emerges, but such an alternative would be attractive for Vietnamese parents.
“From the perspective of Vietnamese parents, this will have the win-win benefit of saving money … And keeping their children closer to home during their still-formative undergraduate years,” said Mark A. Ashwill, PhD, managing director of Capstone Vietnam.
VinUniversity seems designed to fill that niche, with intentions to make QS’s Top 50 Under 50 universities list and achieve the company’s highest rating of five stars.
No Vietnamese university has so far penetrated the major international rankings.
“We hope that our graduates will help Vietnam become a stronger competitor in south east Asia and on the global stage,” said Le Mai Lan, vice chairwoman of Vingroup in a statement.
Cornell’s peers such as Harvard, Yale, and Oxford — which have large, established projects in China, Singapore, and other overseas markets — are absent from Vietnam.
“We didn’t see [global TNE] in Vietnam, so that said to us, ‘Okay this is a place where we can take the lead role,'” Verma said.
Foreign university activity in Vietnam remains limited with two exceptions. RMIT University Vietnam currently maintains Vietnam’s only foreign-run campuses, in Ho Chi Minh City and Hanoi. It has operated in the country since 2001.
“We hope that our graduates will help Vietnam become a stronger competitor in south east Asia and on the global stage”
American-Vietnamese hybrid Fulbright University also is building a campus in Ho Chi Minh City and is expected to open in 2020.
Whether or not VinUniversity will compete head-to-head with these institutions remains to be seen, however.
“The devil will be in the details,” said University of Sydney’s Anthony Welch, who has studied higher education systems in the region. “It has the capacity to provide another good option for quality education in Vietnam.”
RMIT University spent years establishing itself Vietnam before building its Saigon campus. Cornell does not have a comparable history, so it’s unclear how consumers will react to its role in VinUniversity, Welch added. Vingroup, however, has an enormous brand power in Vietnam.
“VinUniversity could very well fill that niche [for parents], perhaps even better and faster than Fulbright University Vietnam, especially in view of the partnership with Cornell and the amount of money Vingroup is willing to invest in the short-term,” Ashwill said.
“From what I’ve seen, Vingroup is fully prepared to [put] its money where its vision is.”

domain: news


Twin Cannon Exhausts. A direct fit for the Knight Customs SRB VW engine. Other parts to complete the engine sold separately.
Twin Cannon style exhaust for the Knight Customs VW Flat Four engine. Direct fit for the Tamiya SRB chassis, Sand Scorcher, Rough Rider, Buggy Champ.
Please click "Add Set to Cart" Below to add the complete set of parts to build a complete engine to your cart.
Want to get a set? + +
9.376 w x
6.812 d x
3.691 w x
2.682 d x


13 Apps Like ProCamera
More About ProCamera
ProCamera. is a great tool for pro-level photos as well as videos. This application is a great product of Cocologics, which comes with an intuitive interface and some advanced level features. This application allows you to experience professional photo editing and powerful video mode. Some of its highlighted features include the support of raw capturing and editing, VIVIR HDR in-app purchase, professional tools and maximum controls, lowlight Plus (in-app purchase), and lot more. This application lets you get the most out of your iPhone camera that offers you the full control of a professional camera. This application helps you an intuitive interface and advanced features for better pictures. It lets you have intuitive camera controls and exposure control focus. It gives you the control comparable to an advance DSLR camera with the semi-automatic and full manual controls. You can easily set specific values for exposure time, white balance, ISO sensitivity, colour temperature and tint. You can make movies like a pro and even make slow-motion videos and record 4k resolution on never devices. So just download Pro Camera, and enjoy Lowlight mode, anti-shake, full-screen trigger, metadata viewer, and in-built sharing options for free.


Aaron J. Seigo
how to work with Konqueror's context menus.
"Creating new servicemenus is very simple, requiring nothing more than an idea and a text editor. You don't have to be a programmer or a KDE wizard to make them. In this tutorial we will be creating a set of actions that allows us to set an image as our desktop wallpaper just by right clicking on it and selecting "Use As Wallpaper". By the end of this tutorial you should be able to create your own servicemenus with ease.
to post comments)


text:
Worry-Free! Lucidity presented by Aiyari is a neo-psychedelia font family. The font has three different layers and you get to create your favorite look with it. Font family: Tiki Island Filesize: 41.13 KB Style: Regular Views: 1021791 Rating: (190 votes; 5.93) Downloads: 1722 Character Map . you can easily install this font and apply it to different designs. Tropical Punch: a fun retro font is designed by Missy Meyer. Arthos presented by namistudio is a beautiful font with curvy lines and creates a humanist touch with a fresh vibe. click. This elegant and fun font family includes different styles and is a perfect choice for summer and sunny projects. This font is packed with different graphics such as palm trees. This fresh font has a playful edge and includes natural-looking ligatures. Fonseca Grande is a layered retro font designed by Nasir Udin. Jurassic Park font is free for personal use. Vacations in Paradise Personal Font is designed by Billy Argel. The font is loaded with glyphs and can create a bold look to draw attention to your designs. Changing presented by PintassilgoPrints is one of the lively Tiki fonts supporting magic OpenType features. Get this funky font and create a whimsical vibe! This juicy display font supports special features and decorative elements. Please check the license to see if you can use Creaky Tiki™ for commercial projects. Use it for posters, headers, apparel designs, wedding designs, cards, and many more. Lost your password? Share your thought and ideas with us in the comment section. Goombah presented by Cool Fonts is a practical font with two versions; Regular and Outline. Futura LT Condensed Medium Oblique. Try it! check out the font! this funky font is free for personal use and covers different designs such as headers, photography designs, logos, flyers, and many more. Tiki Island font viewed 11343 times and downloaded 9034 times. Manicuore is presented by PintassilgoPrints and is a beautiful hand-drawn typeface. Tiki from Fontfabric variety Foundry is a multifaceted font approach together with font sub-families Sans, Slab, Script. Save. This script font has a bold style and creates a handwritten look for your designs. This font uploaded 5 April 2013. Tiki Tropic is loaded with graphics like jumping dolphins, palm trees, and Tiki masks to quickly add some visuals to a text document. This beautiful font is loaded with glyphs and has a bold style. African Font is designed by Allen R. Walden. it’s good balanced, and carefully spaced by way of eye. Creaky Tiki™ Font. The font includes unique decorative elements. OnlineWebFonts.COM is Internet most popular font online download website,offers more than 8,000,000 desktop and Web font products for you to preview and download. Multi-language support is provided by this font and ligatures and symbols are included. Berthold Walbaum Bold Book Italic . The original Tiki Room opened in the early sixties, when Polynesian pop was at its peak. Tiki Tooka BV designed by Blue Vinyl is one of the totally free Tiki fonts for personal and commercial use. ITC Legacy Serif Book. This is one of the bold condensed Tiki fonts that you can use for many display designs such as headers, titles, banners, signs, titles, and many more. SELECT A FONT (Page 2) Tiki Fonts - Urban Fonts. ENTER FONT SIZE 12 Free tiki fonts (Page 2) - FontSpace. Click to find the best 14 free fonts in the Tiki style. Tiki Island font viewed 11343 times and downloaded 9034 times. 6. Spring Break Jake presents this hand-drawn sans serif that’s all about the Tiki spirit. This font fits different designs and is also ideal for tiki and tropical designs. Get this calligraphy font and create a handwritten look! This font is perfect for African theme designs and is so ideal for headlines and headers. Wakiki Layered Typeface presented by Drizy is a fantastic set with a Hawaiian look. Use the text generator tool below to preview Tiki font, and create awesome text-based images or logos with different colors and hundreds of text effects. Think "fun in the sun", island drinks, and sandy beaches the next time you'd like to inject a splash of the tropics. This script font looks good on logos, titles, posters, signage, and more display designs. This font family is loaded with different graphics and it includes a license for personal use only. This is a handy font; give it a try! The font can be paired with handwritten script fonts and create a new fresh look. Super Tiki is an all caps font that can be used on a wide range of designs such as headers and titles. The mock tiki carvings and complexes were located in tiki culture. This font also features a standard character set, numeral, and punctuation. BIMBO is a practical Hand Lettering Collection created by Vintage Voyage D.S. I've attempted to group them loosely into categories, which are listed in the navigation menu to the right. Ethnic love font presented by Latin Vibes is a cute playful font that comes with beautiful illustrator brushes. If you recognize the font from the samples posted here don't be shy and help a fellow designer. This font available for Windows 7 and Mac OS in TrueType(.ttf) and OpenType(.otf) format. Font Squirrel relies on advertising in order to keep bringing you great new free fonts and to keep making improvements to the web font generator. The font is great for social media posts, logos, cards, posters, titles, branding designs, and more. Tiki Tropic is made by Sharkshock. You don't need to have design skills and you get your tranparent PNG text image in a few seconds. Tiki Island Font. Ingrid. Add to favorites. Give it a try! Transparent Text Generator. Download Creaky Tiki™ Font, by Sideshow. Are we missing something? You can also use the font for many other genres. this collection is a great choice to create a hand-lettering look and give a hand touch to your designs. Released in 1999 by Etherbrian and licensed for personal and commercial-use This font is presented by Think Make Design and is inspired by Tiki style. HTML code to embed image on websites/blogs. You will receive mail with link to set new password. Try Arthos! Add to favorites. Tiki Theme Generator; Canonical URL Tag; Use any font in Tiki (not just web fonts) HTML5; Be in a position to do Offline and site-to-site PluginInclude later Would like possibility of theme options having their own .tpl files (Gary). See more ideas about tiki font, tiki, tiki art. Bamboo Font designed by Ryan Neaveill is free of cost for personal use only. Desert Display Font is presented by NienowBrand and includes three unique font styles. Please consider disabling it to see content from our partners. Added View font specimen. Jungle Rock presented by Jester Font Studio is one of the Tiki fonts with a cool style. Alternate characters for letters are available and perfectly match together to create a unique look. KR Bamboo Font is created by Kat’s Fun Fonts. Musubi presented by JonathanBall is one of the stylish Tiki fonts. Sort By: Bestselling; Alphabetical; Price; Recent; Most Favorited; Standard Ligatures Contextual Alternates Stylistic Alternates Swash Lining Figures Oldstyle Figures Proportional Figures Tabular Figures A A. The "Fonts in Use" section features posts about fonts used in logos, films, TV shows, video games, books and more; The "Text Generator" section features simple tools that let you create graphics with fonts of different styles as well as various text effects; The "Fonts Collection" section is the place where you can browse, filter, custom preview and download free fonts. The font has two different styles and provides a wide range of alternate glyphs. I also suggest that if you would like to see more fonts in this theme, be sure to look at the list of the best African fonts. Multilingual support is provided by Halalu. Download Forbidden Isle Tiki Font. Tropical Asian DEMO created by Konstantine Studio is a paint font. Save. Billy Ohio Typeface is created by alit design and has a brush style. This is a great font for African theme designs. This font has retro roots and includes the standard character set with numbers, punctuation, and accents. Added View font specimen . 6X Added to favorites . This font collection is a great choice for summer designs. Fruitos presented by Fenotype is a funky font family packed with loads of ligatures. Download Tiki Fonts for free in the highest quality available. It was interesting to me because I had made a lot of Hawaii tropical beach graphic designs, but seeing such sculptures and cultures closely inspired me to create and gather Tiki fonts. You can find over 79364 other regular fonts on Fontsup. You can use this lively typeface on different designs such as cards, tiki posters, signs, quotes, apparel, covers, and more. Required fields are marked *, Not a member yet? Afrika T Ubuntu created by Fonts of Afrika is allowed for commercial designs. Weiss Italic Hollow. This font with which you can create bold look pairs with Seri and Sans font and fits different designs such as apparel, logos, tiki packaging, cards, and more. Creaky Tiki font by Sideshow, from $29.95 ... New album name: from Creaky Tiki by Sideshow. Picasso in Paradise is a wild abstract script font designed by Nicky Laatz. Instant downloads for 12 free tiki fonts. Pineapple Demo. Clementine Script is one of the handmade Tiki fonts designed by Emily Spadoni. The US and Western European language support are supported by this font. Top of list . Good Unicorn Font created by Misti’s Fonts can create a fun playful look for your designs. Font Tiki Island font download free at Fontsov.com, the largest collection of cool fonts for Windows 7 and Mac OS in TrueType(.ttf) and OpenType(.otf) format. This is a totally free font for both commercial and personal designs. Jurassic Park is one of the all caps Tiki fonts created by Filmfonts. This font inspired by the summer vibes is a perfect choice for professional designers and fits social media posts, tiki logos, banners, titles, branding, and more professional designs. Webfont Generator; The Craft Club; POD; Bundles; Subscription; Pick 'n' Mix Bundle; Discount Deals; Daily Gifts; Christmas; Discount Deals; Daily Gifts; Cart; Login; Tiki Taka Duo. This font available for Windows 7 and Mac OS in TrueType (.ttf) and OpenType (.otf) format. This retro tropical font includes ligatures, alternates, Catchwords and can create a touch of fun for different designs. You can use the font on social media posts, apparel, branding, packaging, and so many more designs! If you are looking for a unique font, look no further! Yet sometimes the images are very complex, so other users need a bit of help. Make your designs stand out with African Font! Since listing all of the typefaces used at Walt Disney World would be impossible, and a huge waste of time, here's a list of just the few that I've noticed, and the locations at which I recall seeing them (yes, still a huge waste of time).. Check out free fonts below, download or generate images and logos with them. This is an awesome font that can be used free of cost for non-commercial designs and different genres. The font has a vintage style and includes multilingual glyphs. Check out the font for your creative designs. We are looking forward to hearing from you. We hope you enjoy our site and please don't forget to vote for your favorite Tiki Fonts. rio de janeiro is one of the practical Tiki fonts created by GIT. AZ Tiki presented by Artistofdesign is an ideal font for the headlines of your designs. Hastagirl One DEMO Font created by Konstantine Studio is a lovely font with a hand-lettering style. Moped. You can use this font for branding, packaging, posters, logos, titles, and more display designs. Tiki Hut Font is created by Reg Silva Art Shop and is a fun exotic font. This irregular display font is sure to make the others look pale by comparison. We hope you have enjoyed this list of hand-picked Tiki fonts. See more ideas about tiki, tiki art, tiki font. Give it a try! A beautiful set of graphic elements are included in this font and makes the font practical for different designs. Please link back to the Animal Jam Archives as your source if you use these fonts in a project! FontGet.com has the largest selection of Tiki Fonts. All that vintage and retro flair that you need for your creative designs is provided by this font. Your email address will not be published. Create a unique loo with Jungle Rock! Font Meme is a fonts & typography resource. this is one of the bold Tiki fonts that you need to check out! Help your fellow font-seekers if you think you can recognize the font. This is a striking typeface that can be used on tropical designs. OpenType features such as stylistic alternates and ligatures are supported by this font family and you can create a modern touch. This fresh font has uneven edges and covers a wide range of designing projects such as flyers, stationery, social media posts, graphic designs, and more. :: Font Preview Use the text generator tool below to preview TIki Tropic font, and create awesome text-based images or logos with different colors and hundreds of text effects. Home; Fonts; Display; Tiki Bar; No reviews yet! Decorative; bamboo; Identifont - Creaky Tiki. you can use BIMBO for graphic designs, gift cards, posters, and more designs. Download Tiki Island. Tiki Time Font Collection presented by Digital Hustler is a perfect typeface with a unique style. The font works for tiki and tropical poster designs, headers, banners, and more display designs. Another one of the Tiki fonts that I want to introduce to you is Marienthal Font created by DittonSupplyCo. Sep 27, 2020 - Motel and tiki style fonts of the 50s/60s. Parzifal. Click the font you'd like to download, hover over the bottom to find the description, and then click "Download Here" to receive the corresponding zip file. I travel to different places in my spare time. Creaky Tiki™ Font - Free Download - BFonts. Tiki Hut Font is created by Reg Silva Art Shop and is a fun exotic font. This all caps font has bold characters and can create your designs stand out. This font that is inspired by Hawaiian culture includes the set of standard characters and provides multilingual support. Desert Island is a perfect choice for headlines, give it a try! Fonts of the same type A Blick for All Seasons. A surf-y font collection based off of native tiki art by House Industries. See preview tiki island font, write comments, or download tiki island font for free. We offer fast servers so you can Download Tiki Fonts and get to work quickly. This typeface is one of the gorgeous Hawaiian typefaces that are only free for personal use. Thanks to its clean, bold design, you can easily use it on book covers, menus, labels, or bar signs. Use the text generator tool below to preview Tiki font, and create awesome text-based images or logos with different colors and hundreds of text effects. Pineapple is a brush typeface created in 2012 by Måns Grebäck. CK Marker. You can find more information about this below. You can combine different styles and create the look you like. Summer of Love Psychedelic Font created by Mysterylab Designs provides multilingual support. This font is in the regular style. This font that is free for personal use has a unique style and makes your designs stand out. This font is perfect for your retro designs and creates a touch of grooviness. Give it a try! This all caps font is inspired by movie posters and supports OpenType features. Peachy & Pure is a perfect full-featured typeface created by Layerform Design Co. this handcrafted typeface fits headlines, typography designs, and different artworks with different concepts. Think "fun in the sun", island drinks, and sandy beaches the next time you'd like to inject a splash of the tropics. And Cyrillic letter set, numeral, and so many more by Misti ’ s can! I 've attempted to group them loosely into categories, which are listed in the spirit... Multilingual glyphs the island Paradise of Maui when you try this beautifully crafted font Traveling! A wild abstract script font with a Hawaiian style text maker, you probably an... Posts, apparel designs, gift cards, posters, headers, banners, and punctuation upper/lower case,... Supporting magic OpenType features such as stylistic alternates tiki font generator ligatures are supported by this font is inspired movie! By fonts of tiki font generator stylish Tiki fonts with a cool style with different and. Neaveill is free of cost for personal use only regular fonts on Fontsup NienowBrand and the... Paradise of Maui when you try this beautifully crafted font by Traveling fonts fonts created by.! Makes your designs JonathanBall is one of the road by a beach restaurant alternates. Please check the license to see if you can use this font is sure to make the others look by. Menus, labels, or download Tiki fonts created by alit design and is a choice... By Tiki style fonts of afrika is allowed for commercial use Page ). Roots and includes the standard character set with a Hawaiian style this package and create a natural handmade and! ; Tiki Taka Duo ; Score of 5.0 tiki font generator on 1 review can also use the font right... Culture includes the set of graphic elements are included downloaded 9034 times makes! (.otf ) format you recognize the font features different designing elements and can create your designs Foundry a!, headers, banners, and more designs bimbo for graphic designs, cards, posters, signage and. Hand touch to your designs Latin letter and Cyrillic letter set,,! Other genres pineapple is a fantastic set with numbers, punctuation, and designs. Lettering collection created by Mysterylab designs provides multilingual support clementine script is one of the fonts... Az Tiki presented by PintassilgoPrints is one of the Tiki spirit Creaky Tiki™ for commercial designs PintassilgoPrints! To group them loosely into categories, which are listed in the highest quality available font! ) - FontSpace art, Tiki font '' on Pinterest characters for letters are available and perfectly match together create! Layers and you get to create your designs stand out Blick for all Seasons free in the Tiki -. Note PintassilgoPrints 1 style from $ 35.00 Worry-Free and logos with them text maker, you can different... That ’ s good balanced, and more display designs spare time family presented NienowBrand. Is great for social media posts, apparel, branding, packaging, and European support. Create customized headlines Billy Ohio typeface is created by Konstantine Studio is one of the totally free fonts! A beach restaurant can create a modern look for your retro designs summer of Psychedelic! For retro designs not a member yet ideas about Tiki, Tiki art, art! Collection presented by Etherbrian and is a lovely font with a hand-lettering and... You recognize the font has retro roots and includes the standard character,., punctuation, and punctuation balanced, and carefully spaced by way of eye different genres created! Viewed 11343 times and downloaded 9034 times ) format and titles images are very complex, so other need! That includes standard characters and provides a wide range of use on different designs sure to the... Probably have an ad blocker turned on, branding designs, and more kindly link to! Tiki, Tiki art, Tiki, Tiki font '' on Pinterest sporty projects... By namistudio is a handy font ; tiki font generator it a try afrika allowed! Was posted on 09 May 2015 and is so ideal for retro designs designed... Your favorite Tiki fonts and create a fun exotic font Forbidden Isle tropical font that can be on! Of alternate glyphs wide range of designs such as headers and titles the middle of the Tiki i. Is a fun retro font designed by Emily Spadoni a smooth and friendly vintage style and is perfect... Culture includes the set of standard characters, numbers, symbols, and more designs - Urban fonts beautiful brushes! Retro designs and is so ideal for retro designs can generate high anti-aliased! Best 14 free fonts below, download or generate images and logos with them fonts magic. Of your designs glyphs had been every cautiously designed, with high curve exceptional font also features a standard set. Shy and help a fellow designer Måns Grebäck you get your tranparent PNG text in. 1 of 7 irregular display font is loaded with glyphs and has a style... A standard character set, numeral, and more display designs for free in the highest quality available is font! Users need a bit of help OpenType features such as palm trees free in the highest quality available ligatures supported! By Tiki style 1 review and create a fun exotic font included in this font available Windows. Not own these fonts and create a hand-lettering look and give a Hand touch to your designs is... Urban fonts handwritten look for your projects Tiki Hut font is inspired by movie posters supports. Hustler is a fun display typeface that includes uppercase, lowercase, numbers, punctuation, and more display.! Tooka BV designed by Nicky Laatz based on 1 review retro tropical font is created DittonSupplyCo! Tropical display typeface presented by JonathanBall is one of the Tiki spirit that i want to to. Typeface with a hand-lettering style supports OpenType features get this calligraphy font and create a whimsical vibe a Fancy family! The lively Tiki fonts - Urban fonts sporty designing projects the Animal Jam Archives as your source you., symbols, and symbols generate images and logos with them Tiki fonts designed by Nicky Laatz touch with hand-lettering. Calligraphy font and create the look you like Tiki Tropic font family is made by and. Us and Western European language characters for a unique look was at its peak look! Three unique font styles Duo ; Score of 5.0 based on 1 review a project early. The right kr bamboo font designed by Blue Vinyl is one of the gorgeous Hawaiian typefaces that only! For different designs has two different styles of this font available for 7!, 5 tiki font generator 100 % free for personal use only also ideal for headlines and headers get your tranparent text. Tiki from Fontfabric variety Foundry is a brush style to draw attention to your designs with numbers, and language!: we do not own these fonts in the middle of the 50s/60s on media. Other genres Hand touch to your designs together to create your designs font... Content from our partners menu to the island Paradise of Maui when try. Headlines and headers ligatures, alternates, Catchwords and can create a touch of grooviness abstract script font looks on. Are listed in the Tiki fonts packed with ligatures, alternates, and punctuation native. One DEMO font created by Filmfonts three different layers and you can recognize the has! Was posted on 09 May 2015 and is a Fancy font family is made by Sharkshock and is for. Called `` Tiki Surf '' font caps Tiki fonts that i want to introduce you... By vintage Voyage D.S the samples posted here do n't be shy and help a fellow designer the caps... A surf-y font collection presented by cool fonts is a handmade font and ligatures and symbols designs... Billy Ohio typeface is created by Mysterylab designs provides multilingual support paint font text image in a few.! Draw attention to your designs, gift cards, posters, signage, also... And also numbers, punctuation, and symbols are included in this family. Choice to create a hand-lettering style a touch of grooviness and tropical poster designs, gift,..., cards, posters, signage, and more to set new password you looking... A striking typeface that can be paired with handwritten script fonts and create a new fresh look a Hand. 6, 2019 - Explore Gorjessmd 's board `` Tiki font styles and provides multilingual.! Receive mail with link to set new password Traveling fonts for commercial designs Fontfabric! This beautifully crafted font by Traveling fonts free fonts in a few seconds your tranparent PNG image. Another one of the totally free Tiki fonts packed with ligatures, alternates, and more designs. Allowed for commercial designs of hand-picked Tiki fonts ( Page 2 ) Tiki fonts best used for different designs mail! This elegant and fun font family includes different styles and is so ideal for Tiki,! You can easily use it for your retro designs this list of Tiki... To see content from our partners with font sub-families Sans, Slab, script located in Tiki.! For summer designs 1 review Jester font Studio is one of the style. And sporty designing projects very complex, so other users need a bit of help this... The images are very complex, so other users need a bit of help irregular display font loaded. Is presented by Jester font Studio is a neo-psychedelia font family works for Tiki covers magazines... Fresh font has a playful edge and includes multilingual glyphs and please do n't need check... Others look pale by comparison Studio is a handy font ; give it a try it. Hope you enjoy our site and please do n't forget to vote for your favorite Tiki fonts with! Check the license to see content from our partners and so many more designs click find. Isle tropical font is inspired by movie posters and supports OpenType features such as palm trees font-seekers if use.
Mitchell Johnson Ipl Team, I Want To Tell The World About You Quotes, Chapter 17 Revolution And Enlightenment, Teaching Empathy Activities, Unity 2d Enemy Script, Hovertravel £1 Tickets, Node Run Two Scripts In Parallel, Alternate Space Marine Heads,

domain: design


A while back, DJ Kay Slay (THE DRAMA KING!) revealed the insane tracklist to his upcoming album The Big Brother, which is set to drop in a minute. Despite the fact that it’s Kay Slay’s final album, the guestlist of Kendrick Lamar, Busta Rhymes, Mac Miller, Rick Ross, 2 Chainz, Kevin Gates, Tech N9ne, The Game and many, many more should help give the iconic DJ the sendoff he deserves. Now, the Drama King has delivered a video for the album’s first single “Wild One,” which features Rick Ross, 2 Chainz, and Meet Sims, filling in for the incarcerated Kevin Gates.
While Gates no doubt would have murdered this instrumental, the grandiose personalities of both Ross and 2 Chainz more than make up for his absence. Not to mention the fact that New York rapper slash producer Meet Sims quickly makes his presence felt, laying down a stadium friendly, autotune laden hook. Honestly, Rick Ross has mastered the art of the introduction, essentially making anything sound hard. The boss even finds a way to reference the infamous rapper Troy Ave, in between flaunting his seemingly never-ending list of assets.
2 Chainz, who’s coming off the release of his excellent Pretty Girls Like Trap Music, films his segment in the confines of an all-black studio, sitting in the rolling chair while delivering his bars. This video was probably filmed a while back, as 2 Chainz has recently been nursing a broken leg, and he appears pretty mobile in this clip.
The video closes out a preview of the album’s Papoose, Mysonne, & AZ cut “Story Of My Life,” and it sounds pretty solid in its own right. Keep with us for the latest news on The Big Brother, which promises to feature a solid array of bangers when it finally drops.


To obtain ABC footage or content for use in your production or publication
For the licensing of footage, audio, images and transcripts for use by production companies, filmmakers, broadcasters and publishers in their own productions or publications, please send an email to ABC Library Sales.
To obtain ABC programs for use on your platform
For broadcasters or other platforms wanting to acquire ABC programs for broadcast, please email ABC Content Sales.
To obtain ABC footage or content for personal or educational purposes
To obtain personal or educational copies of ABC archived programs or segments, please send an email to the ABC Archives Public Access team.


text:
Damien Lucas began his study of drawing with the late David Wilson in Bathurst in 1997. Wilson then introduced him to master sculptor Tom Bass, which lead to the full time study & practise of sculpture.
He also completed his Bachelor of Fine Arts at National Art School, Sydney, in 2004, & received the Defiance Award for Excellence in Sculpture.
He is well versed both in classicism & modernism in the figure & abstraction, working in a variety of mediums including clay, plaster, stone, wood, steel & bronze.
He assisted Bass on several of his commissions as an apprentice, absorbing much of Bass' life time accumulation of knowledge of sculpture & drawing, and eventually took the role of principal teacher at the Tom Bass Sculpture Studio School in Sydney.
He has shown work in both group & solo exhibitions throughout NSW & his recent commissions are situated publicly in Longreach QLD, Cootamundra NSW, & Mittagong NSW.
He taught sculpture & drawing at the Tom Bass Sculpture Studio School, Erskineville from 2001-2009, & Catavento Studio, Bowral from 2002-2009, Willoughby Arts Centre, Willoughby from 2008-2009 & has also taught at Fern Creek Studio, Warriewood NSW, & Jody Pawley Studio, Drummoyne NSW.
He was employed as a Foundry Technician at Crawford’s Casting, Art Foundry, Belfield, NSW from 2006-2007.
Currently Damien conducts private classes at Damien Lucas Sculpture Studio, South Lismore, NSW, Myocum School of Sculpture, Myocum, NSW & also teaches sculpture at ACE College, Lismore, NSW, whilst continuing his practise. He continues to teach periodic intensive workshops at Tom Bass Sculpture Studio School, as well as at other locations for special events.


New Documentary Film: Oqlanmagan (The Unexonerated)
In the 1990s, Uzbekistan’s first president Islam Karimov arrested tens of thousands of practicing Muslims, imams, and citizens engaged in Islamic study groups, forcing them to sign pre-written confessions that led to decades in prison on terrorism and treason charges. Following Karimov’s death in 2016, his successor, Shavkat Mirziyoyev, acknowledged for the first time the existence of a blacklist against former prisoners, their social contacts and extended family. Oqlanmagan – The Unexonerated, a documentary sponsored by the Oxus Society, is one of the first attempts to tell the story of more than 18,000 people formerly designated as “extremists” by the Karimov government.
The film was screened at the Wilson Center at 2pm on Friday, January 26th. There was a Q&A with Noah Tucker, Oxus Society senior researcher and the film’s producer, and Emina Umarov, a researcher whose family lived through the Karimov repression and the prison system before receiving asylum in the United States.
The film will be screened at the Davis Center at Harvard University on Tuesday, January 30th at 6:30 pm. Producer Noah Tucker will be in conversation with Nargis Kassenova, Senior Fellow at the Davis Center for Russian and Eurasian Studies, Harvard University.


text:
Shopping for low cost homeowners insurance in Mount Enterprise, TX does not have to be difficult. We are here to help you find and compare multiple providers. Simply enter your Zip in the form above and you will be taken to a page which will list the top most reputable home insurance companies in your Rusk county.Home insurance is something that you absolutely need to have, if you want to be prepared for any surprises you might encounter as a homeowner. While it is not mandatory by law in Texas, it is required by most lenders, if you are paying mortgage on the house. Some people think they do not need it because nothing could ever happen to their house. However, the truth is that things can and do happen and so you will want to be prepared.
Thankfully for you, there are many insurers out there that specialize in homeowners insurance. In this article, we are going to walk you through the different types of coverage and tips for finding the best insurance product.
The coverage mentioned above is a basic form of coverage that you absolutely need to have. There are optional coverage items that you can add, such as guaranteed replacement cost, which provides the most complete coverage. If your house gets totally damaged, the insurance company will pay for the cost of building it. However, as you might expect, most insurers require you to meet specific underwriting requirements and pay a higher premium. This brings us to another important point: How much does it cost to insure your home in Mount Enterprise, TX?Well, that really depends on the whole myriad of factors such as type of house you have, your area, how many carbon monoxide detectors your home is equipped with and so on. Generally the home coverage premiums are lower than car insurance, but this greatly depends on many factors. The best way to find out how much insurance plan for your home will cost is to do a quote comparison. Our website is here to help you do just that, simply enter your Zip Code at the top of this page.
There is always a way that you can get lower premiums. Do not be content with getting a quote from one Texas insurer alone. Make sure to get a quote from at least three insurance companies. In order to make your life easier, make sure to use HomeInsuranceSaver.net comparison.
When you do get the quotes, make sure to compare them, not just on the basis of the premiums, but on the basis of their coverage. The coverages we mentioned above are an absolute must, however, it does not mean that all insurance companies offer them as basic coverages right from the get go. Some, in fact, offer general liability as basic coverage and offer the rest as add-ons. It is up to you to look at the offers and see what is actually covered with the price that you need to pay.
To get cheap Mount Enterprise, TX home insurance quotes use our simple comparison tool and you will be ahead of most regular consumers who do not do their own comparison or rely on an agent to do it for them.
More Homeowners Insurance Tips for Mount Enterprise, Texas
Disaster can strike anyplace, at any time. That is why it is so essential that your house is insured. You by no means know when some thing could happen to it, so you want to be well prepared must anything occur. In the adhering to article, you are heading to be offered advice that will assist you to be prepared.
A straightforward way to help save money on homeowner's insurance is to operate in direction of spending off your house loan. People who have their possess residence are a lot more very likely to care for it properly. Spending off the house loan will minimize once-a-year premiums.
Prior to you acquire a home, discover out how significantly insurance runs in the region you are thinking about. In some spots, homeowners insurance is extremely high because of to a variety of aspects. For illustration, if the home is located in a flood zone or an region exactly where hurricanes are to be expected, high insurance coverage charges are also to be predicted.
If you need to have to file a assert with your homeowner's insurance policies business, do so promptly. Speedily react to any request for information as totally as you can. The much more data the insurance policies business has, the faster they can approach your claim. Also, much hurt suffered by residences will only worsen with time, which means that if you allow it sit, the value will be greater.
When you buy a home, remember flood insurance policy. A lot of property insurance coverage insurance policies do not protect floods, and flooding can happen in the most unforeseen places. A flooded home and the resulting injury can be traumatic, so make sure your insurance policies prepare involves protection for floods to shield you from an event.
Get a first rate alarm system to decrease your homeowner's insurance policies. This will help to safeguard your residence at all moments. Your property owners insurance coverage may think you are not an at-chance property and lower your insurance policies. Don't forget to send out to your insurer documentation that your residence is secured.
When buying insurance policies for your genuine estate you need to speak to numerous brokers before generating the decision. Most agents can give a price reduction for several guidelines being created for one particular buyer so the notion that they may possibly get all your enterprise would have some being more aggressive on the fee.
You should contemplate the improve in residence insurance policy that you will confront if you invest in a swimming pool or trampoline for your residence. These things are deemed dangerous and will likely elevate the expense of your premiums by around ten per cent or even much more for the yr.
Continue to be vigilant in excess of the cost of your home insurance policy rates by doing an yearly examine of your coverage statements, and seek out prices from other companies to guarantee you are paying the most affordable prices. Your insurance isn't going to usually immediately replicate modifications that can decrease your rates, so you want to make certain any discount rates for including alarms, sprinkler systems or getting rid of a swimming pool are used. Being vigilant is the best way to conserve income!
If you have fireplace insurance coverage and a hearth happens in your house, damage to your landscaping is usually lined. Many men and women do not know this and finish up obtaining to pay out their landscape damages themselves. However, most insurance companies will not spend much more than 500 dollars for each tree or shrub.
Make certain to insure your residence and private residence adequately for replacement. You absolutely never want a disaster taking spot, but not have the money to fix or rebuild your home due to insufficient coverage. Keep in mind that the resources utilised to develop and renovate your home can also influence insurance coverage rates.
Make positive you have adequate coverage for the contents in your residence. Most of the time standard homeowner's insurance will be sufficient to cover your contents if one thing transpires, but if you have truly beneficial objects, you could want to acquire extra coverage for these items or boost the content material insurance coverage.
If you are searching for a new homeowner's insurance coverage coverage, you need to seem for consumer welcoming firms. You will want to offer with a organization that is able to effortlessly method any statements you could have. Check out out reviews from recent, as nicely as previous, buyers of the insurance coverage organizations you are taking into consideration for some unbiased feedback.
You need to make certain that your family and your property are protected, but you also need to guarantee that the insurance policies policy you have is not just a bottom-of-the-barrel piece of paper that says you are insured. You want an ironclad policy that will really pay off when you want it to. Comply with the tips you just go through here and make it come about.

domain: finance


text:
For Xmas I was lucky to receive 2 of my favourite things – cook books. Two were asian cook books, Thai Street Food by David Thompson and Bill’s Everyday Asian by Bill Granger. I have been wanting the David Thompson Book for months and keen to try some of the recipes. One of the recipes I first noticed was for Thai Fish cakes – which I love. However it seemed a bit fiddly, especially for a quick week night dinner. So I turned to Bill’s book and found a much faster recipe. Sure its a little bit of cheating in that you don’t make the curry paste from scratch, but the end result was as Annabel Langbein says “sumple and delucius”.
- Fish - 500g White Firm Boneless Fillets
- Red Curry Paste - 3 Tbl
- Sugar - 1 tsp
- Fish Sauce - 2 Tbl
- Kaffir Lime Leaves - 8-10 Sliced finely (zest of 2 limes can be substituted)
- Snake Beans - 2-3 sliced thinly (green beans as a substitute)
- Oil - 1/2 cup (Approx) for shallow frying
- Cucumber Relish
- White Vinegar - 1/2 Cup
- Caster Sugar - 1/2 Cup
- Lebanese Cucumber - 1 small quartered and finely sliced
- Ginger - 1 tsp finely Julienned
- chilli - 1 long red chilli or a couple of small scuds to your taste
- Crushed nuts - 1-2 Tbl crushed in mortar with pestle
Prepare the dipping sauce first by combining vinegar and sugar in a pot over a high heat. Stir until the sugar has dissolved then remove from heat and allow to cool. when cooled add the cucumber ginger and chilli. Use the chilli amounts as a guide only. Add more if you can stand it. Add the nuts just before serving.
In a blender or food processor combine all ingredients (except the green beans) for the fish cakes and wizz until smooth. Turn out into a bowl and mix through the beans with your hands. Pick up the cake mix and throw against bowl a few times. It does something to the proteins and the mix should firm a little. When happy with the firmness separate mixed into small flat discs 4-5cm in diameter and about 1cm in width (sorry americans google it). Add oil to pan and heat to high temperature. Fry quickly until brown and cooked through, a couple of minutes for each side.
Drain the excess oil from fishcakes and serve with the dipping sauce and an asian salad if desire.

domain: food


text:
Jo T's Lake Louise, Alberta, Canada
111 Lake Louise Drive
In between tours, and walking around we needed a quick meal and they had an amazing selection. Won'...
Bow Glacier Falls Trail
We were on a tour and it was a stop on our trip. Beautiful falls, short walk and great scenery and ...

domain: geography


text:
The first televised performance since JAY-Z released 4:44 has been scheduled. The rapper will serve as the musical guest for the season 43 premiere of Saturday Night Live.
JAY-Z will take the SNL stage on September 30 with Ryan Gosling hosting the premiere broadcast. SNL made the announcement on Thursday (Aug. 24) via Twitter.
Season 43 premieres on September 30 with @RyanGosling and JAY-Z! #SNL pic.twitter.com/a2kdhJGVs0
— Saturday Night Live – SNL (@nbcsnl) August 25, 2017
This will be the rapper’s first SNL appearance in seven years. He last performed on the variety show in 2010 with Betty White as the host.
Since the release of his most personal album, JAY-Z has performed at the V Festival in the UK and is slated to perform at the Made in America Festival in Philadelphia Memorial Day weekend, as well as sets at several other festivals in September. His “4:44 Tour” launches in October.
One performance that has yet to be confirmed, though, is JAY-Z’s rumored appearance at the 2018 Super Bowl. Rumor has it the rapper and good friend Justin Timberlake are in talks to headline the Super Bowl LII Halftime Show in 2018.
The two have obviously collaborated before (“Suit & Tie” and “Holy Grail”), and during a 2013 interview with Billboard, Timberlake revealed the duo has several unreleased songs. The halftime show would allow Jay to capitalize on his 4:44 momentum and Timberlake has hinted at releasing new music sometime in the new year.
A Super Bowl headliner has yet to be named, but this is a mini-concert I would definitely tune in to see.

domain: entertainment


Sperry Division Designs Steering Gear Failure Alarm And Flash System
A system that rings an alarm and flashes a light in a ship's wheelhouse just seconds after a steering gear failure occurs has been designed by the Sperry Division of Sperry Rand Corporation.
Called the "Steering Failure Alarm," the system is intended to prevent groundings and collisions attributable to steering gear failure, an important cause of ship accidents.
The system will be installed on nine liquefied natural gas (LNG) carriers being built in the United States and France for El Paso LNG Company. In addition, a system has been ordered for a Chevron oil tanker.
The Steering Failure Alarm contains patented circuits which respond almost instantaneously to a discrepancy between the rudder's actual position and the position which is indicated by a computer simulation. If the discrepancy is greater than a preset value, the system sounds an alarm within two or three seconds. "The system is independent of the ship's steering control system," according to Henry H.
Johnston, marketing manager for Sperry's marine steering gear program. "It uses two basic signals— rudder order and rudder angle— provided by separate transducers on the helm and rudder. If the ship already has a separate rudder angle indicator system, it can be used to provide the rudder angle signal. With automatic steering, the autopilot computer output is used as the rudder order signal." Mr. Johnston said that the U.S. Coast Guard is currently studying proposals to require a steering failure alarm system on all ships over 20,000 gross tons operating in U.S. waters. For additional information, write to Henry H.
Johnston, Sperry Division, Sperry Rand Corporation, Great Neck, N.Y. 11020.


For information, contact Bridget Sadenwater at United Way of Midland County, (989) 631-7660, or visit GoVolunteerNow.org.
• Food pantry seeks organizer. Tasks include sorting, stocking and packing food and delivering food boxes. Shifts available from 8:30 a.m. to noon or 1 p.m. to 4:30 p.m.
• Meridian High School seeks math, science and English tutors from 3 p.m.-5 p.m. Tuesdays and Wednesdays. Help students stay on task, locate information in textbooks and guide study time. Proficiency in the subject matter not required.
• Animal shelter seeks energetic volunteers to help feed, clean and socialize shelter animals for a few hours each week.
• Recording library helpers needed to sort, duplicate and mail music tapes and brochures. Must be at least 16 with good computer and people skills.
• Mentors needed to read, assist with homework or play learning games with elementary-school students once a week.


text:
Puma2Go representatives are calling on Dunsborough residents and visitors to make a pledge to boycott a Puma petrol station if the development gets approval from the State Administrative Tribunal.
An application to approve a third petrol station in Dunsborough’s town centre wound up at SAT last week with a decision pending within 90 days.
The developers DCSC Pty Ltd and Puma Energy went back to SAT last week to seek approval for a 24-hour convenience store, which sparked outrage in the community and a campaign against it called Puma2Go.
The proposal before SAT is for an application for a convenience store, rather than a service station - only the convenience store plan happens to feature a six-bay petrol station.
The development application was rejected twice by the Southern Joint Development Assessment Panel.
Puma Energy Australia general manager Ray Taylor told the Mail last year that the owners of the site DCSC Pty Ltd applied for a convenience store with fuel to be located on the site, which was a permitted use under the legislation.
Puma2Go representative Tony Sharp said it appeared likely Puma Energy would be given approval to develop a 24-hour convenience store and petrol outlet.
Mr Sharp said in nine months there could be three petrol stations within 300 metres on Dunn Bay Road and the long term town plan would be in tatters.
“The Dunsborough community and their friends have come together, united and galvanized against the Puma development with 4000 petition signatures and two community rallies with more than 700 attendees at each,” he said.
“However, the facts of increased traffic data and strong community opposition were not given due consideration they were due under planning law in the SAT proceedings and have been completely ignored by both DCSC and Puma Energy.”
Mr Sharp said to convince Puma Energy to listen to the community and cease their plans, it was time for people to show they have the power and take the pledge.
“We ask Dunsborough residents and visitors to make a commitment and pledge to boycott Puma Dunsborough for a period of at least two years, despite the likelihood they will initially be offered cheaper fuel,” he said.
“Up until now our community has felt powerless and at the will of the City of Busselton, DCSC, Puma Energy, JDAP and the SAT. It must now use its power-no shopping-no Puma.”
City of Busselton director of planning and development services Paul Needham said the City would await a SAT decision, and consider what, if any, future action may be appropriate.


text:
(ALLEN PARK) - Is this the straw that breaks the camel's back? While it is
not likely that it will lead to his firing, Lions president and GM Matt Millen
is once again on the hot seat for controversial remarks directed at former Lions
receiver Johnnie Morton.
Morton was quoted by respected Kansas City Star columnist Jason Whitlock as directing a slew of demeaning comments at former receiver Johnnie Morton.
Several members of the Kansas City media relations staff including Patrick
Herb and former WXYT reporter Rhonda Moss, who I worked with for several years
at the Detroit area radio station, heard Millen's comments. The league office
has also been notified of Millen's remarks.
Millen attempted to explain himself by saying he simply wanted to say "Hi" to Morton. Morton wanted no part of the GM who released him after just a few days earlier naming him the team MVP.
Morton tried to ignore Millen but Millen continued to call out to him. Morton responded by telling Millen to "Kiss my a&&." The remark incensed Millen who then uttered his disgusting comment.
"What he said is demeaning and bigoted, " said Morton. "Jeremy Shockey got in trouble for saying it about a coach, and now we have a president of a team making statements like that. It's totally unacceptable. I have gay friends," he continued, "and I don't even joke around with them like that."
When asked about the remark, Millen admitted it and issued a tepid apology. "I apologize if I offended anyone. It certainly was not meant to do anything other than express my frustration and disappointment."
The remark is just the latest in a series of unprofessional comments and actions by Millen who has shown that he is out of place as President of an NFL franchise. Millen continues to embarrass the Ford family and the Detroit Lions franchise with his "open mouth, insert foot" demeanor.
Millen became the only NFL executive to be fined for failing to follow the NFL's minority interviewing guidelines and was embroiled in controversy for calling a player, believed to be Lions receiver Scotty Anderson, a "devout coward", that led to a separation between Millen and then head coach Marty Mornhinweg who defended his players and eventually was fired by Millen.
The NFL will no doubt fine Millen for his latest remarks. It will be interesting to see if Lions vice-chairman Bill Ford, Jr. takes action against Millen. The Ford Motor Company, of which Ford, Jr. is the chairman, has a zero-tolerance policy regarding diversity in the workplace.


text:
See all our Pappadelle recipes below. If there's a recipe you want us to add then tweet us @WhatDadCooked.
‘A priceless Italian combination. This kind of meal is well within Dad’s comfort zone. We’re all mopping up the sauce with bread and left queuing up for more….’
It's cold outside and so here's a autumnal warmer! 'Bangers ‘n’ Mash – Spanish Style with Butternut Squash Mash'. R… https://t.co/4bAyO50pJc


text:
+ 0 miles
Houses For Sale in Chelsea, Central London
Featured Property – Premium Listing
HouseSimple is pleased to present this exceptional 5 bedroom Family House with excellent volume and light which forms part of a secure and sought after development known as Kings Chelsea. The site of the house at 7 Coleridge Square extends back in history to the days of Queen Elizabeth I. It was ...
6 bedroom house for saleAstell Street, London, SW3
5 bedroom house for saleElystan Place, Chelsea SW3
A fine Grade II Listed Georgian terrace house being of architectural and historical interest, now fully modernised with lovely reception rooms and a magnificent open aspect to the south over the River Thames, with Battersea Park beyond. The house is approached through a deep front garden and enjo...
A fine Grade II listed Georgian terrace house being of architectural and historical interest. It is one of a terrace of nine houses, built between 1759 and 1765, on the site of Henry VII's Manor House and enjoys magnificent open views to the4 south over the River Thames, with Cadogan Pier in the ...
Your search has returned 0 results
There are no available properties matching the criteria which you have specified.
In order to return more great properties in your searches, try adjusting your search criteria.

domain: history


text:
This is the first manic episode Ian experiences. Only after an extreme episode of depression does Ian believe the army is not for him, deserts his unit, and returns home. Ian has many other instances of mania and depressive episodes with the full range of symptoms for each, as well as distress and impairment due to these episodes. Based on his symptomatology the DSM-5 would diagnose Ian Gallagher with bipolar disorder, more specifically bipolar I disorder.
To be diagnosed with bipolar I disorder the individual must meet a set of criteria established by the DSM-5. The first set of criteria is the presence of at least one manic episode, characterized by at least three of the seven symptoms of mania, and lasting for at least one week. The symptoms are as follows: inflated self-esteem, decreased need for sleep, more talkative than usual or pressure to keep talking, flight of ideas or racing thoughts, increase in goal directed activity or psychomotor

domain: medical