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The travel industry is working hard to reduce its impact on climate change. Travellers are acutely aware of sustainability and responsible travel, and there are initiatives helping the aviation industry combat the effects of carbon emissions.
Many governments across Europe are raising public funding to stimulate economies and travel post-Covid. Environmental issues will be a significant factor in future deals, with investment in lower-carbon transportation to and from airports high on the agenda. It has been suggested that rail networks can replace short-haul flights within Europe. Many countries have ambitious plans to expand their railway infrastructure, which is further backed by the European Union. The French recently voted in favour of a bill to end short-haul internal flights where the same journey could be made by train, and the German Aviation Association (BDL) and Deutsche Bahn (DB) signed an agreement to improve connectivity between aviation and rail.
It is clear that airlines and train companies are quickly understanding that combining their transport networks will result in a win-win situation for both suppliers and consumers, and there is a strong need for new technology platforms that integrate air and rail and provide seamless connections between the two. Intermodal or door-to-door travel is gaining momentum for airlines, airports, and feeder traffic providers and competition is increasing to provide for future travellers’ requirements and the entire Intermodal chain.
Connecting transport systems and flights is not new; in fact, it has been around for at least ten years, but recently that interest has gained momentum. Airlines are partnering with individual train companies. A Lufthansa – Deutsche Bahn partnership has existed for more than a decade with 17 German cities connected, but the airline has recently announced that they are expanding the service to 5 more cities and aligning their product for better consumer experience, offering flight and train bookings in a single transaction.
The technical platforms enabling airlines to offer these products have been around for a while too. The problem is that many existing solutions were conceived in the pre-internet era with a standard airline model in mind. Airline business models have evolved since, but legacy systems have prevented more dynamic cooperation between different industry providers. Travellers are typically unable to select the ancillary services available on the train leg of the journey – business class, legroom, meals, rebooking, flexible fares and so on. These systems are complex and expensive and settlement of payments between the carriers is difficult, which means they are usually not an option for low-cost airlines.
This is where companies such as Dohop make it a level playing field for LCCs by growing their virtual interline offering to include intermodal connections. Dohop’s technology is for both LCCs and full-service carriers, and as the industry’s attention is turning towards virtual interlining, it is crucial that this technology connects other types of transport providers than just airlines.
This does not come without its challenges. There are technical issues to overcome, such as standardising train and railway data and integrating content from more than one train carrier and multiple train stations.
Carriers need technology to put out rich content that was previously unavailable. Airlines must be able to display full seat maps, sell fare bundles, make ancillary services available to their customers and enjoy instant settlement. This has a tremendous upside effect on a carrier’s revenue and brings down transaction costs. Moreover, such cooperation between airlines and rail results in a higher network multiplier effect for both parties. Airports are generally located outside the city, whereas trains can take the passengers right to the city centre, thus covering gaps in the network. A quick glance at the Emirates website will reveal that they partner with all 5 major Rail networks in Europe – Deutsche Bahn in Germany, SNCF in France, OBB in Austria, Renfe in Spain and Trenitalia in Italy – despite their own expansive European network covering as many as 38 destinations, underlining the importance of air and rail intermodality.
Linking air & ground networks have proven to dramatically expand an airport’s catchment area. Examples of this can be seen in Brussels or Amsterdam or at Paris’ Charles De Gaulle Airport. An International long-haul flight may be landing at just one Airport in a country but through a rail partnership, it can cover all the secondary cities. This means an airport doesn’t just attract passengers from the vicinity of the city but also residents from within 200-300 km. Airports, therefore, should be especially keen to expand air and rail partnerships and allocate space and budgets to develop infrastructure that seamlessly connects the passenger journey. Loss of a few short-haul flights may lead to some loss in revenue but airports earn more revenue and more passenger throughput, embrace an environmentally responsible strategy, and also provide choices to their passengers.
Furthermore, travel companies have started aggregating train content from multiple operators and are offering it either directly to end-users or as a B2B service. These aggregators have lowered the technical barrier by offering and connecting train journeys from different railways, and a number of OTAs and travel platforms now offer trains as a transport option. This API or shared interface approach also makes it possible for low-cost airlines to offer a full service – flight and train bookings – in a single transaction using simple and affordable technology.
Competition in the aviation industry has undergone a change in paradigm. Airlines need to widen their customer reach around an airport by connecting other modes of transport to and from airports. By connecting with ground transport providers, airlines can broaden their network and generate more traffic by providing multi-airport connections in cities or regions where major airports are within close distance to each other. This represents an important step in the move towards more sustainable travel, recognising that connections are important, but perhaps that it is time to replace some flying with alternative modes of transport. In order to facilitate this, it is essential that customers are offered these choices


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Background/aim: The aim of the study was to evaluate the serum concentration of main chemokines and interferons in patients with diagnosed endometriosis. Materials and methods: A total of 160 women were divided in two study groups (group 1 - endometriosis; group 2 - healthy women). Serum levels of IFN-α, IFN-γ, MCP-1, MIP-1α, MIP-1β, RANTES, eotaxin, IL-8, MIG, IP-10, and IL-17A were measured with Human Multiplex Cytokine Panels. Results. Serum levels of IFN-γ, MCP-1, and IL-8 were significantly higher (mean 14.03, 57.24, and 534.24, respectively, compared to 0.58, 20.51, and 259.82, respectively), and serum levels of IP-10 and eotaxin were significantly lower in women with endometriosis compared to the controls (mean 1.15 and 1.01, respectively, compared to 3.90 and 3.22, respectively). Conclusions. According to our results women with endometriosis have elevated levels IFN-γ, MCP-1, and IL-8, and lower serum levels of IP-10 and eotaxin, indicating unbalanced immune activity in endometriosis.
Chemokine, inflammation, endometriosis, interferon
MALUTAN, ANDREI MIHAI; DRUGAN, TUDOR; CIORTEA, RAZVAN; BUCURI, CARMEN; RADA, MARIA PATRICIA; and MIHU, DAN
"Endometriosis-associated changes in serum levels of interferons and chemokines,"
Turkish Journal of Medical Sciences: Vol. 47:
1, Article 17.
Available at: https://journals.tubitak.gov.tr/medical/vol47/iss1/17

domain: chemistry


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Little Mix is currently performing on their "LM5" tour, and it seems to be going smoothly. Band member Jesy Nelson recently shared a photo of her on stage, which seemingly stunned her Instagram followers.
In the concert snap, the "Think About Us" hitmaker is holding the mic out to the crowd and wearing a huge smile on her face. Nelson is sporting a jeweled leotard, which has a sheer netted garment attached to it. Her legs and arms are on full display, showing off her tattoos under the spotlight -- including the "once upon a time" writing on the inside of her upper arm.
Nelson -- who is known for frequently changing her hairstyle -- is wearing her long, wavy hair down in the shot.
Within five hours, the post racked up more than 335,000 likes, proving to be a hit with her followers.
Little Mix is currently in the middle of the European leg of their tour, which Nelson references in the caption. After asking fans if they are ready for the upcoming Amsterdam concert, Nelson's followers were quick to respond in the comments section.
"It's my birthday today and I'm seeing you tonight, I'll be singing as loud as I can," one user wrote.
"OMG BEAUTYYYYYY," another fan shared, adding a heart-eye emoji.
"You're a real angel," a third user wrote.
"That smile gets me every time," a fourth fan remarked.
"You look stunning," a fifth follower commented.Nelson recently did a documentary with the BBC, Odd One Out, which saw her open up about the online bullying she endured regarding her appearance.
Prior to the show airing, Nelson did an interview with The Guardian and revealed that she used to starve herself for days because she felt she had to look a certain way, per The Inquisitr.
"I'd starve myself… I'd drink Diet Coke for a solid four days and then, when I felt a bit dizzy, I'd eat a pack of ham because I knew it had no calories.""I could see that I was losing weight and sometimes I'd see a few good comments and that spiraled me to be like: 'This is how I need to stay.'" Nelson added.
On Instagram, Nelson expressed how overwhelmed she felt by the response of the show, proudly announcing that it broke BBC records.Little Mix will continue their tour across Europe and will play across the U.K. and Ireland throughout October and November. Little Mix won their second BRIT Award this February for the single "Woman Like Me," featuring Nicki Minaj. The group took home the trophy for Best British Video. To keep up with Little Mix, follow the group's Instagram page.

domain: entertainment


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There are three diagnostic methods used to identify viruses; the direct, the indirect and serological techniques. Complement fixation test is one of the serological tests used in virology to identify the presence of specific antibodies or antigens. In this context, complements are proteins in series form within the patient’s serum which act in response to an antibody antigen complex. In case the reaction takes place on a membrane, pores are produced causing damage to the cell.
• Commercially produced complements from guinea pig
• Patient’s serum
• Red blood cells preferably from sheep
1. In complement fixation test, venous blood is collected from the patient and serum isolated.
2. It is natural for individuals to differ in the quantity of complement in serum. With the purpose of eliminating any negative effects these complements might have on the test results, the serum complements are substituted with standardized complement proteins. The complements are destroyed through heating, but care is taken to preserve the antibodies. This can be achieved because complements are vulnerable to heat than antibodies. Thereafter, the standard complements area added into the serum.
3. Into the serum, the antigens of concern are added and the preparation incubated.
4. Red blood cells are added into the preparation
In complement fixation test, incubation is necessary as it gives complements a period to fix itself onto antibody antigen complex, that is, if it is present. If this happens, complements will not be available to act on the red blood cells and cause hemolysis. As a result, a positive test is designated by the presence of the red blood cells. The cells are observed at the bottom of the beaker. On the contrary, a negative complement fixation test is indicated by the lysis of the red blood cells. The red color of hemoglobin is observed as it spreads in the beaker due to lysis.
Testing for antigens:
It is a common practice in serology to test for antibodies in complement fixation test. Nevertheless, it is feasible to test for antigens. In this case, the test serum is supplemented with antibodies which must be specific in nature. This induces the formation of complement.
Advantages and disadvantages:
The test is cheap as it does not call for expensive equipments and reagents. Again, a large number of viral infections can be screened using complement fixation test. However, it should be noted that the test is labor intensive and frequently non specific.

domain: biology


text: Willie Nelson has suspended his tour indefinitely after three members of his band were hurt when their bus plowed into a bridge pillar in East Texas during rainy conditions. Nelson was not aboard the bus when it crashed about 3:30am local time on Interstate 30 near Sulphur Springs, 75 miles northeast of Dallas. Two band members have minor injuries, while the third was seriously hurt, say police. Their names and conditions weren't immediately released. Seven people were on the bus, including the driver, who was dealing with wet roads and high winds.

domain: news


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- Band Management
- Home Recording
- Live Sound
- Best Instruments
- New Music & Video
Where: at The 5 Spot – Nashville, TN
When: March 11
Highlight: A power trio that didn’t skimp on the power.▼ Article continues below ▼
The term “power trio” covers a wide swath of three-piece bands, but its most basic, guitar-bass-drum, fuzzy-toned and hard-hitting version was on glorious display on a Sunday night in East Nashville. The Paranormals, a Nashville by way of Birmingham band of young but seasoned players, brought a level of confidence not often seen in a newly formed group, but this swagger is justified. Their songs are, quite plainly, great. Heavy on groove, with catchy riffs and choruses that latch on to the brain stem, these are tunes that can get a room moving, even in normally reticent Music City.
The seven-song set opened with the punchy “Whiskey and Cigarettes” and settled in with “Figure it Out,” a standout for drummer/lead singer David Sutton, whose unique phrasing make it one of their best. Not to be outdone, guitarist Jarrod Randall and bassist Heath Hendrick traded distortion-laden riffs on “You Gotta Go,” bringing to mind the best that The Black Keys and Drive-By Truckers have to offer.
After cruising through “Balls” and “See Ya 5 and a Baby,” the band showed their sense of dynamics by slowing down for the intricately picked “Burns On and On” before finishing strong and sweaty with “Oneonta.” The Paranormals have it all: the tunes, the chops, and that rare quality that separates a great rock band from a good one. As the bumper sticker says, “It ain’t bragging if you can back it up.” The Paranormals can. And on this Sunday night, they did.
Photos by Lacey Criss

domain: artistic


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Real money for virtual world – Gone are the days when bankers didn’t care about cryptocurrencies. Even the one where they fight and denigrate them seems about to be over. In any case, the large banking group HSBC is one of those who have already turned the page, to fully embrace the development of technologies provided by Bitcoin (BTC) and its ilk. HSBC therefore intends to invest more and more in metaverse.
The multinational banking HSBC Holdings has clearly shown its desire to make inroads into the metaverse on March 16, 2022, by purchasing a LAND (virtual plot of land) in the digital world of The sandbox (SAND).
But this first step was simply the harbinger of greater entry into force in this new field of application of crypto-assets that are “metaverse”. Indeed, as reported by Reuters in particular, HSBC has just launched a investment fund in metaversesfor its (very) wealthy clients of Singapore and hong kong.
This new investment vehicle, called “Metaverse Discretionary Strategy Portfolio” will be managed by the branch HSBC Asset Management of the banking group. This fund aims to offer wealthy investors (professional or accredited) the possibility ofindirect exposure to crypto projects such as The Sandbox or Decentraland (MANA).
>> While waiting for the metaverse version of your crypto exchange, register on the FTX benchmark crypto platform (affiliate link) <
Metaverses, a nascent ecosystem already “full of opportunities”
In detail, the fund Metaverse Discretionary Strategy will focus on five development sectors of the metaverse ecosystem, namely: infrastructure, computing, virtualization, user experience, and interface.
“The metaverse ecosystem, while still in its infancy, is rapidly evolving (…) We see many exciting opportunities in this space [des métavers]and companies from different backgrounds and of different sizes are already flocking to this ecosystem”
Lina Lim, Head of Asia-Pacific Investment Funds for HSBC
HSBC is not the only banking institution to make a marked foray into the digital worlds of metaverses. Indeed, from February 2022, the mega-bank JP Morgan has opened virtual offices there. And various other players, such as big brands and companies, want to appear in crypto metaverses – if only for advertising purposes.
When the biggest banks in the world focus on an investment, it is not useless to be interested in it too! To not miss the opportunity of a lifetime, Register without delay on the FTX reference crypto exchange platform and benefit from a lifetime discount on your trading fees (affiliate link, see conditions on official website).


The new horror comedy Totally Killer is going to premiere on Amazon Prime Video. It is set to release on October 6, 2023. The film stars Kiernan Shipka (Chilling Adventures of Sabrina) as Jamie, a teenage girl who accidentally time travels back to 1987, the year of the original killings by the infamous “Sweet Sixteen Killer.”
The trailer for Totally Killer shows Jamie struggling to adjust to life in the 1980s, while also trying to stop the killer from striking again. Along the way, she teams up with her teen mom (Olivia Holt), who is also a target of the killer.
- 15 Top Ghosted Movie Filming Locations
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- The 10 Best Thriller Movies in Telugu
The film also stars Julie Bowen (Modern Family), Charlie Gillespie (Julie and the Phantoms), Liana Liberato (The Act), Lochlyn Munro (Riverdale), and Randall Park (Fresh Off the Boat).
Director and Others:
Totally Killer is directed by Christopher Landon (Happy Death Day) and written by Landon and Sarah Rothschild. The film is produced by Blumhouse Productions, the studio behind such horror hits as Get Out and The Invisible Man.
The trailer for Totally Killer has been met with positive reactions from fans and critics alike. The film is being praised for its humor, its suspense, and its 1980s nostalgia.
If you’re a fan of horror comedies, then you’ll definitely want to check out Totally Killer when it premieres on Amazon Prime Video on October 6, 2023.
Totally Killer is a new horror comedy that is sure to please fans of the genre. The film has a great cast, a suspenseful plot, and a 1980s setting that will transport you back in time. Be sure to check it out on Amazon Prime Video on October 6, 2023.
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Video: UFO Sighting Near Mercury or Natural Phenomenon?
By ranina sanglap | December 9, 2011 2:48 PM EST
Is the image caught on camera by NASA spacecraft a cloaked UFO spaceship lurking near Mercury or just an after image of the planet itself?
A video of the bright object posted by YouTube user "siniXster" had over 2.4 million views by Friday with many wondering if aliens are already amongst us.
U.S. officials dismissed the speculation and said the yellow circle captured was Mercury itself.
The video footage taken by the Heliospheric Imager-1 (HI-1), a camera system aboard NASA's STEREO spacecraft, managed to capture what looks like a large cylindrical object orbiting the planet Mercury. The footage shows a coronal mass ejection spewed from the sun last week. The solar flare struck Mercury and seemed to have hit another object nearby that was only revealed after it was hit by the CME. This behavior prompted UFO enthusiasts as a sign that the object was clearly an alien spaceship.
"What object cloaks itself and doesn't appear until it gets hit by energy from the sun?" asked siniXster. "Holy smokes. That is definitely some sort of manufactured object."
The poster identified himself only as Daniel, a 42-year-old resident of Detroit, Mich.
Turns out, the actual explanation for the mysterious object doesn't involve little green men. Scientists at the United States Naval Research Laboratory (NRL) say that this image is actually Mercury itself. According to NRL's Russ Howard, head scientist, and Nathan Rich, lead ground systems engineer, the UFO is simply an image of Mercury from the previous day and was visible because of the way the telescoped data is processed.
NRL scientists remove background light when processing telescope data to make the glow of the coronal mass ejection more visible against the bright glare from space. The scientists identify background light from footage captured from the telescope the day before. The background light is eliminated from the footage and the rest of the light is enhanced.
"When [this averaging process] is done between the previous day and the current day and there is a feature like a planet, this introduces dark (negative) artifacts in the background where the planet was on the previous day, when then show up as bright areas in the enhanced image," said Rich.
In essence the UFO is really just a visual after-effect or a ghost image of Mercury that was photographed from the day before.
"It's a complicated effect," Rich told the Huffington Post. "It's basically the background that is removed from the image to bring out the faint coronal signal. It's a negative imprint on the background."
So it looks like Earth is safe from cloaked alien ships once again. Check out the video footage below and judge for yourself.
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Who does not know the famous actor of Tollywood, Prabhas in today’s time, he always remains in the discussions due to something, while Megastar Prabhas is going to celebrate his birthday today i.e. on 23 October 2020 and is expected That his forthcoming project is to be announced today. The makers of the upcoming film ‘Radhey Shyam’ and Pan-India star Prabhas have released the first look. Which is very encouraging to the fans of this film. Prabhas is going to be seen in the role of ‘Vikramaditya’ in this film.
While promoting his film, Prabhas has shared a post on his social media account, which he captioned – “Big moment has come !! Here we introduce #Vikramaditya #Prabhas document in #RadheShyam picture! … # Prabhas & @hegdepooja starring #RadheShyamSurprise #HappyBirthdayPrabhas. ” In this post, you can see that Prabhas is seen smiling in a black dress.
The film may be released soon, while Pooja is going to be seen as a music teacher in this movie. Radhe Shyam is also going to be released in many other languages. Not only this, the fans of Prabhas are eagerly waiting for his upcoming film.
— UV Creations (@UV_Creations) October 21, 2020


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It has been reported this week that the Department for Work and Pensions (DWP) has been ordered to pay substantial compensation to a disabled employee who was dismissed after the DWP allegedly failed to follow its own procedures. It is understood that even though the DWP had obtained no less than eight occupational health reports, the employee was never assessed in person. The DWP are said to have initially refused to accept that the employee even suffered from a disability.
Judgments such as this serve as an important reminder for employers, when dealing with cases involving employees who suffer from medical conditions, to ensure that appropriate and fair procedures are followed. It is important in particular to bear in mind the following points:
- Be aware that for the purposes of the equality legislation a “disability” can cover an extremely wide range of conditions, both physical and mental. The key issue is whether the particular condition has a substantial and long term adverse effect on the employee’s ability to carry out normal day to day activities. For example, if an employee is absent from work on a long term basis due to severe anxiety, that could potentially amount to a disability depending on how that person’s day to day activities are impacted.
- Do not rely on medical advice alone to make a decision on whether you consider the medical condition amounts to a disability. Although a medical opinion will be very important, the test as to whether an employee is disabled is a legal one, not a medical one, so it is important to consider whether the legal test has been met.
- Even short term and intermittent absences from work could be caused by a medical condition which amounts to a disability. It is often the case that employers will issue warnings following trigger points after certain periods of absence. However, if the absence (or some of the absence) is due to a disability then it may be appropriate to discount the disability related absence. This will depend on the particular circumstances. It is therefore important to keep accurate records of the reasons for and length of absences in order that different absences can be distinguished and you are aware of any underlying health conditions.
- Other reasonable adjustments should always be considered to assist an employee with a disability. Each situation needs to be looked at very carefully, as each affected employee will have different needs. Examples of adjustments include allocating duties to other staff, altering hours of work, allowing work from home and providing assistance for physical disabilities such as a workstation which is adapted to take account of the particular medical condition.
- Where appropriate seek medical input from the employee’s own doctor or refer them to occupational health or a specialist. Employers should be extremely wary of deciding to take action, and in particular dismissing an employee, without medical advice having first been sought. It is also important to be aware of employees’ statutory rights, and inform them of their rights, under the Access to Medical Reports Act 1988.
It is important that employers do not make assumptions about what they think should be acceptable in terms of arrangements to assist disabled employees, and ensure that decisions which are made follow on from a process which is fair and transparent.

domain: law


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As a child, I loved reading and writing. I spent my days coming up with stories and daydreaming characters and plots. I drew and painted lots of artwork for them, too. I never dreamed someday I would be an author!
I spend lots of time writing my books, but I also teach writing to college students, helping them make their stories and writing stronger.
Other than writing, my favorite thing is music. I began studying the violin as a child and practiced a lot. I studied it in music school in college, and one day, I became a professional violinist, teaching violin and music to students of all ages and playing in orchestras around the world.
I live with my family and our three sleepy cats near Lake Michigan outside of Chicago. We love to read, watch movies together, travel, and play board games.


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To help commemorate 22 years of offering the most up-to-date health information available, I’ll review 22 currently top trending health topics based on our internal search results.
For each topic, you’ll find a short summary or overview. For more in-depth information, follow the hyperlinks provided in each section. You
"My All-Time Top 30 Health Tips"
In this interview, Dr. Steven Gundry, medical director for International Heart & Lung Institute and director for Center for Restorative Medicine, reviews some of the...Mercola 2019-08-11
Dengue fever is a mosquito-borne tropical disease caused by the dengue virus. Symptoms typically begins three to fourteen days after infection. This may include a high...The Times of India 2019-07-31
Enzymes are proteins composed of individual amino acids. They are necessary to speed up many cellular functions and biological processes. Your body secretes enzymes to...Mercola 2019-07-29
Stir them into yogurt, dust them with cinnamon or eat them straight from the punnet - nothing beats tucking into a bowl of berries on a hot summer's day. And beyond tasting...Belfast Telegraph 2019-08-06
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During the past 22 years of providing the latest research and information to help you make informed decisions regarding your health, it’s been interesting to see the trends and developments in medicine, science and technology. It’s always a positive step to equip yourself with the most up-to-date information rather than relying on conventional medicine for your health...Mercola 2019-08-12
LOS ANGELES, July 31, 2019 /PRNewswire/ -- Bio-Up Mimetic Technologies Inc., a biotechnology company that invented a patent-pending proprietary liposomal technology, announced today it has launched Bio-Up®, a functional beverage brand that uses a liposome delivery system to deliver nutrients more efficiently into the bloodstream. The brand has developed two functional teas,...PR Newswire 2019-07-31
Liz Connor July 31 2019 12:40 PM 0 Comments Summer berries and their health benefits Independent.ie Stir them into yogurt, dust them with cinnamon or eat them straight from the punnet - nothing beats tucking into a bowl of berries on a hot summer's day. https://www.independent.ie/life/health-wellbeing/healthy-eating/summer-berries-and-their-health-benefits-38362579.html...Irish Independent 2019-07-31
With high quantities of protein and good fast present in eggs, they are the ideal foods for thosewho are looking to lose weight. They optimise bone health, help build lean muscles ad stabilise blood sugar levels. Consuming eggs can curb over-eating, minimises insulin spikes and ensures that you end up feeling full for a longer time. They are a very convenient and economical...Deccan Chronicle 2019-08-17
While medicine cannot be entirely replaced by your diet, certain foods are known to have protective qualities. Your eating habits have a profound impact on disease risk, coupled with other factors like lifestyle. While supplements can replicate the effects of most elements, and are easily available in the market, it’s the best to go for natural items. Here’s a guide on which...Deccan Chronicle 2019-08-09
Purple cabbage also known as red cabbage is a nutrient-dense vegetable, which is widely consumed across the globe. It belongs to the same family as broccoli, cauliflower, brussels, cabbage, kale and other brassica family vegetables. Purple cabbage contains comparatively more nutrients and fewer calories that makes it an ideal vegetable for people aiming for weight loss. This...The Times of India 2019-07-31

domain: medical


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Mazars Payroll Newsletter – February 2016
Mazars Thailand’s latest newsletter focuses on updates from the Revenue Department, Social Security Office, Labour Law and other HR related matters.
Keywords: Mazars, Payroll, Thailand, Personal Income Tax, Social Security Office, HR, Ministry of Finance, Property
23 February 2016
Our newsletter contains articles on.
- Tax benefit for first-time home buyers
For more information on payroll or other HR related matters please do not hesitate to contact the Mazars Payroll Outsourcing team.

domain: economics


Chandigarh: Punjab Congress vice-president and former Faridkot MLA Kushaldeep Singh Dhillon was arrested by the vigilance on Tuesday. He was called to the SSP Vigilance office in Ferozepur for questioning today.
After this, the vigilance team also raided the residence of former MLA Dhillon on Faridkot-Kotkapura highway.
Along with Dhillon, Gursewak Singh of village Dhanna district Faridkot and Rajwinder Singh of Nanaksar Shaheed village in Ferozepur district have been booked for corruption after a vigilance inquiry
Dhillon had been facing a vigilance probe since a few months after the formation of the present government in the state, and he has been questioned in the Faridkot Vigilance DSP office several times in the past.
The Punjab Vigilance Bureau on Tuesday arrested former Faridkot MLA Kushaldeep Singh Dhillon for allegedly amassing assets disproportionate to his known sources of income, a vigilance spokesperson said.
He said that a five-year investigation period was fixed by the Bureau from 01-04-2017 to 31-03-2022 to assess all his movable and immovable assets.


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Author(s): Toyoshiba H, Sawada H, Naeshiro I, Horinouchi A
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Abstract Numbers of microarrays have been examined and several public and commercial databases have been developed. However, it is not easy to compare in-house microarray data with those in a database because of insufficient reproducibility due to differences in the experimental conditions. As one of the approach to use these databases, we developed the similar compounds searching system (SCSS) on a toxicogenomics database. The datasets of 55 compounds administered to rats in the Toxicogenomics Project (TGP) database in Japan were used in this study. Using the fold-change ranking method developed by Lamb et al. [Lamb, J., Crawford, E.D., Peck, D., Modell, J.W., Blat, I.C., Wrobel, M.J., Lerner, J., Brunet, J.P., Subramanian, A., Ross, K.N., Reich, M., Hieronymus, H., Wei, G., Armstrong, S.A., Haggarty, S.J., Clemons, P.A., Wei, R., Carr, S.A., Lander, E.S., Golub, T.R., 2006. The connectivity map: using gene-expression signatures to connect small molecules, genes, and disease. Science 313, 1929-1935] and criteria called hit ratio, the system let us compare in-house microarray data and those in the database. In-house generated data for clofibrate, phenobarbital, and a proprietary compound were tested to evaluate the performance of the SCSS method. Phenobarbital and clofibrate, which were included in the TGP database, scored highest by the SCSS method. Other high scoring compounds had effects similar to either phenobarbital (a cytochrome P450s inducer) or clofibrate (a peroxisome proliferator). Some of high scoring compounds identified using the proprietary compound-administered rats have been known to cause similar toxicological changes in different species. Our results suggest that the SCSS method could be used in drug discovery and development. Moreover, this method may be a powerful tool to understand the mechanisms by which biological systems respond to various chemical compounds and may also predict adverse effects of new compounds.
This article was published in Toxicol Lett
and referenced in Journal of Computer Science & Systems Biology

domain: literature


text:
Favourable self-esteem is incredibly essential for our general health and fitness and wellness as human beings. Owning optimistic self-esteem is also important for advertising any style of healing, no matter whether actual physical, emotional or religious. Bad or lower self-esteem on the other hand can be rather detrimental to our nicely-being and even our quite existence. Negative self-esteem can build anxiety, tension, loneliness, depression, complications with associations, significantly impair educational and task effectiveness and also can generate an elevated vulnerability to drug and liquor abuse and dependency. On the other hand, a individual with good self-esteem tends to be far more inspired in getting on and producing a lifestyle that he loves, living it powerfully and in this system be authentically connected to others in his community. Acquiring good self-esteem appears to be important for having a joyful and healthier existence regardless of who we are or what occupation we are using on in lifetime.
What is self-esteem? We typically imagine that self-esteem is basically about how we feel about ourselves at any distinct moment. Though seemingly existing in degrees, we are inclined to consider that we have favourable or unfavorable self-esteem and that we make that determination just by how we sense about ourselves. However, within just a discussion of Transformational Counseling, our emotions or feelings do not exist by itself or have an impartial existence. We do not just merely experience. Fairly, for just about every feeling or emotion that we have, both positive or adverse, there is a corresponding believed that we have about ourselves that generates the working experience of self-esteem. Whether or not positive or destructive, self-esteem is merely how our organism activities the views that the specific has about himself or herself. If a human being has favourable views about himself he will knowledge constructive or fantastic self-esteem. On the other hand, if the personal has damaging ideas about who he thinks he is then he will working experience inadequate or unfavorable self-esteem. Therefore, to definitely understand what self-esteem is all about and extra importantly to be in a position to alter it when necessary for ones wellness or therapeutic, we will have to 1st get it that self-esteem is definitely about our pondering, and far more precisely about the feelings that we establish or create about ourselves. The thoughts or beliefs that we have about ourselves are essential in that they figure out or make the structure of our encounter of self-esteem and the several emotions associated with it.
We also are likely to believe of our self-esteem as being one thing that is formed by the functions that choose spot in our daily life, significantly all those from our previous. We are inclined to consider that who we consider we are and how we feel about ourselves is merely the item, result or prompted by the activities that we have experienced in the earlier, that we are who we are by virtue of what has took place to us as human beings. More especially, we tend to assume that the lead to in the make a difference of who we feel we are and our self-esteem is because of to circumstance, circumstance or many others, individuals, areas and points. We do not are likely to consider that our self-esteem is something we in fact created or developed. In the do the job of transformation, it is not the previous, circumstance, situation or some others, that decides our fundamental self-graphic and corresponding self-esteem. We developed our ideas and with it our feelings from the which means that we gave to the functions that took spot in our life, especially at an early age. As indicating producing machines we give that means to anything in our existence which include and most importantly to ourselves. At an early age the indicating that we give an function tends to be produced out to be all about us. While gatherings do materialize it is not the situations that are important but alternatively the this means that we give them and in particular how we created it out to be about our identity.
Supplied the point that our ideas determine our feelings or thoughts and similarly vital that we are truly liable for their generation, to modify or transform our self-esteem, how we have a tendency to truly feel about ourselves, amounts to us altering how we see or conceive of ourselves in the environment in the now and this get the job done is our duty by yourself. It is our self-impression, how we define ourselves as an particular person in the planet in the current, that decides our expertise of self-esteem and it is this that we are certainly liable for developing and equally accountable for transforming. When we alter or completely transform our definition of ourselves in the existing we alter how we sense about ourselves and with it our working experience of truth and everyday living in general. If we do not get it that we are liable for what we imagine about ourselves and that we are the actual creator of our self-image and self-esteem we will carry on to blame a thing or some overall body, continue to be powerless and stuck in lifestyle. The issue of how to essentially go about altering or enhancing an individual’s self-esteem is one that has been debated for quite a few a long time by gurus each in the psychological overall health and addiction arenas.
Self-esteem can be enhanced or transformed in various means. Just one way to enhance kinds self-esteem is to do the function of transformation as outlined in my content, Transformational Counseling and The Dialogue of Transformation. To strengthen ones self-esteem in this fashion is to turn into current to ones self restricting perception, that which has stopped us in everyday living and in the procedure produce new options for oneself, a new self-graphic from which to start to stay life into. Yet another way to strengthen an individual’s self-esteem is by way of the use of optimistic affirmations. Given that the basis of self-esteem is the feelings that a particular person has about himself, an particular person with inadequate or adverse self-esteem is believing adverse thoughts or suggestions about who he thinks he is. The person may imagine, for example, that he is “worthless” or “not very good more than enough” and as a outcome will are inclined to expertise weak or destructive self-esteem. In just the operate of transformation and Transformational Counseling, the believed that is at the foundation or core of our self-converse is defined as a person’s Self Restricting Belief, the fundamental or core perception about who we feel we are. Until this core imagined or belief that a particular person has about himself is adjusted or remodeled he will keep on to knowledge a bad or detrimental self-esteem and as a end result of this destructive assumed pattern generate or crank out life experiences that will match and validate what they consider about them selves. Given these types of a cognitive and psychological problem daily life will carry on to show up as it has in the past and kinds foreseeable future will just be the probable just about specified upcoming.
Employing constructive affirmations can be a quite strong resource for reworking what a individual thinks about himself and as a final result make improvements to the individual’s self-esteem. Reliable use of optimistic affirmations will completely transform the destructive beliefs about who a particular person thinks he is into favourable ones, will start to change the foundation and framework of his self chat or inner voice and generate a transformation from lousy self-esteem to optimistic self-esteem. Although used in a many approaches, operating with beneficial affirmations will be extra powerful when sent through or merged with therapeutic rest audio. What therapeutic relaxation music does to enrich the effect of good affirmations is to produce a really relaxed audio atmosphere for the personal to become even much more open up or suggestive to the language of constructive affirmations. When therapeutic leisure new music is put together with binaural audio tones the audio room that is created for the delivery of beneficial affirmations is even more enjoyable and as a consequence extremely impressive. In addition to using a distinctive sort of therapeutic rest audio, the infusion of both theta or alpha binaural tones is very important for the success of this kind of intervention. When therapeutic relaxation tunes and binaural audio tones are merged in this trend the individual will working experience a quite deep point out of rest and as a end result be more open up to the reception and eventual acceptance of the favourable affirmations.
The key to the effective use of constructive affirmation in this or any other kind of intervention is consistency. The self-picture and the detrimental ideas about who a particular person thinks he is that generates his encounter of lousy or negative self-esteem is nicely established in the his perception program. In a lot of scenarios the improvement of a adverse self-image took yrs to generate and has been bolstered by means of repetitive behavioral validation. The moment a person generates and then thinks that a self-limiting belief is real he will constantly act as if it is correct. This seemingly essential belief will show up to the human being as correct and as a consequence will continually be acted on and thus be reinforced by means of types habits. A lot of that person’s habits will be to regularly validate who he thinks he is. Kinds behavior will always be directed at supporting, reinforcing and validating what the man or woman thinks is accurate about him. When essential for kinds perfectly-becoming and health, these kinds of a transformation of ones self-image from getting essentially a negative a single to 1 that is basically constructive does not materialize instantaneously. As with the enhancement of an individual’s adverse self-impression, the progress of a more satisfactory perception about the legitimate nature of the unique will necessitate dependable and repetitive do the job by the man or woman. Essential to this process is that the particular person must thoroughly embrace his feeling of total duty for the development of his self-picture and also for its transformation. To do in any other case will only go away the individual experience powerless and not able to produce the everyday living that he or she definitely wants and unless there is regularity and repetition this kind of a transformation will basically not take place.
Enhancing My Self Esteem is an audio products that will correctly completely transform the incredibly composition of an individual’s imagined or perception pattern, the basic concepts and language framework that he employs to outline who he thinks he is in the planet. This product was designed specifically to transform the self-speak that a human being ordeals on a every day foundation by changing the thoughts or beliefs that the individual has about himself, the incredibly foundation or backdrop of his interior discussion. As our identification is merely language, adjust the language in a person’s thoughts and his lifetime transforms. By listening to this product or service an specific has the chance to follow or repeat fifty beneficial affirmations that will empower them to alter their everyday living. Within just a conversation of Transformational Counseling, committing an affirmation to spoken word will make it so or true specifically if it is performed continuously. Listening to good affirmations in advance of snooze also permits the person’s intellect to start off this restructuring or reprogramming process even though the person sleeps by using the words and phrases and language into their desire condition. By constantly listening to and practicing the favourable affirmations in this item the specific will have the chance to begin to redefine them selves, who they think they are in the entire world, from 1 that is destructive to a person that is optimistic and boosting for their everyday living. With the acceptance of the text and language of the positive affirmations will arrive an improved self-picture and with it an knowledge of beneficial self esteem.
I am at this time making use of Improving My Self Esteem with all the consumers that I counsel at the Holistic Dependancy Cure System in North Miami Seaside, Florida. All of the purchasers that I have labored with who are encountering a drug and/or alcohol dependency trouble also have pretty low self-esteem. My purchasers are likely to be incredibly depressed and unmotivated in many if not most of the many domains of their daily life, together with and especially with their restoration. When supplied to my consumers as homework, consistent use of Enhancing My Self Esteem alters how they think and improves how they come to feel about on their own. With an enhanced self-picture and enhanced self-esteem my shoppers become far more enthusiastic in their life and in particular with their recovery. If a human being carries on to experience low self-esteem and there is no intervention to disrupt the underlying cognitive method taking on improving upon their daily life and functioning the 12 Action System will be meaningless and inevitably presented up entirely as so quite a few other points have been in the earlier. It is my belief that not altering or reworking the fundamental framework of kinds self-impression accounts for the excellent percentage of people today who get started recovery and at some point relapse. The do the job that is critical to prosperous restoration is for the particular person to be capable to redefine who he thinks he is, to change his self-impression, the quite basis of his knowledge of self-esteem and lifetime. Who the specific thinks he is will ascertain what he does and how he will be in and appear to other individuals and the planet.
Harry Henshaw, Ed.D., LMHC

domain: psychology


DUBLIN–(Business WIRE)–The “World Good Seat Belt Technological know-how Current market Dimension, Share & Marketplace Developments Examination Report by Propulsion, Product sales Channel, Car or truck Type, Regional Outlook and Forecast, 2022-2028” report has been added to ResearchAndMarkets.com’s offering.
The World Good Seat Belt Engineering Sector sizing is envisioned to reach $27.9 billion by 2028, mounting at a market progress of 6.5% CAGR during the forecast period of time.
Numerous aspects like increasing shopper consciousness of car or truck safety and a rise in visitors incidents are envisioned to spur marketplace enlargement for good seat belt know-how. Moreover, the sector for wise seat belt engineering is predicted to profit from a rise in automobile safety benchmarks and enhanced vehicle generation in emerging nations in the around potential.
If nations’ producing and output criteria were to adhere to a range of UN motor vehicle basic safety standards, several life might be saved. They demand that manufactures guarantee that almost all cars have seat belts and airbags. Road accidents significantly raise the risk of interior and external injuries if these essential prerequisites are not met.
On the other hand, increasing customer disposable cash flow is boosting demand from customers for luxury vehicle sales, which are characterised by improved safety measures as standard machines. This aspect is hastening market growth as perfectly. Thanks to the mounting general public recognition of the will need of driving properly, there is a growing demand for seatbelts, which has contributed to the market’s enlargement.
COVID-19 Influence Assessment
Because of to the disruptions induced by the pandemic in the automotive, transportation, and tourist industries, automotive component companies have modified their operations in response to the coronavirus pandemic.
As a outcome of the COVID-19 pandemic’s disruption of source chains and manufacturing schedules, vehicle generation and income suffered substantially, which experienced a detrimental impact on the current market for smart seat belt technology in 2020. Sensible seat belt product sales are intricately similar to the all over the world automobile manufacturing and profits industries. If the around the globe lockdowns are extended, output losses would most likely increase.
Sector Expansion Things
Increase in the Awareness amongst Shoppers towards Automotive Protection
Globally, highway mishaps are a main be concerned, particularly even though travelling on highways with large visitors and inadequate weather circumstances. As for each the Globe Well being Organization, 1.25 million persons die just about every year in traffic mishaps around the globe. In latest years, customers’ lifestyles have gotten more and more chaotic, with damaging driving tactics these kinds of as world wide web searching, texting, and speaking on the cell phone when driving resulting in vehicle mishaps.
Enlargement in the Quantity of Road Incidents
Inspite of the rapid growth of the automobile industry as a final result of its significant advantages and enhancements, the soaring threat of street incidents for riders often serves as a component proscribing automobile use. Every 12 months, hundreds of thousands of motorists are involved in incidents in the United States. As for each the information produced by the Countrywide Highway Site visitors Protection Administration (NHTSA), in 2019 there had been a cumulative of 6,756,000 police-noted motor auto site visitors collisions.
Market Restraining Components
Superior Original Price and Elaborate Framework
The significant value of applying basic safety programs in vehicles is predicted to restrain the growth of the smart seat belt technologies market place, as it raises the price of the auto. The expense of installing sensors joined with clever seat belt technology contributes to the elevated rate of vehicles. Moreover, intelligent seat belts give additional functions like as buckle raise, pretension, and far better security in contrast to classic seat belts nevertheless, their price tag is significantly greater than that of passive seat belts.
Scope of the Analyze
Marketplace Segments Lined in the Report:
- Active Seat Belt
- Energetic Buckle Lifter
- Intelligent Ignition System
- Notice Retention Process (ARS)
- Electrical & Hybrid
- Alternate Gas Car or truck
By Income Channel
- Initial Products Producer
By Car Sort
- Passenger Cars
- Hefty Business Vehicles
- Light-weight Industrial Vehicles
- North The united states
- Rest of North The united states
- Rest of Europe
- Asia Pacific
- South Korea
- Rest of Asia Pacific
- Saudi Arabia
- South Africa
- Relaxation of LAMEA
Important Market Gamers
Listing of Providers Profiled in the Report:
- Autoliv, Inc.
- Continental AG
- Denso Corporation
- Tokai Rika Co., Ltd.
- ZF Friedrichshafen AG
- Hyundai Mobis Co., Ltd.
- GWR Protection Devices
- ITW Automotive Products and solutions GmbH
- Joyson Protection Programs Aschaffenburg GmbH
- Yanfeng Global Automotive Engineering Co. Ltd.
For extra data about this report visit https://www.researchandmarkets.com/r/e1gi8s


Maintenance Group Leader Jobs in Charlottesville, Virginia
Currently, there are no Maintenance Group Leader jobs available in Charlottesville, Virginia which match this search. You may wish to explore similar job titles on the Maintenance jobs in Virginia page or view related jobs below.
Position Summary With general supervision from a Lead Technician, Maintenance Supervisor, or Maintenance Manager, a Technician B performs all drive train component work (on diesel and non-diesel equipment and trucks), as well as suspension and steering systems repairs and maintenance on heavy equipment and, where necessary, can perform basic tire work, such as replacement, tire rotation, etc., an...
Maintenance Apprentice needed for med size apartment community for seniors. Perform a variety of services keeping customer service in mind. Entails 24 hours per week between the hours of 8 and 5, Monday - Friday - in the Pantops area. Share on-call duties with other staff. Ideal for students. May increase hours in 2015. Apply online to TheShelterGroup.com - extensive background checks and drug tes...
Northrop Grumman Electronic Systems is seeking a Carpenter, Maintenance Mechanic for our Charlottesville, VA facility. Under general supervision, the Carpenter, Maintenance Mechanic will assist in the maintenance and repair of company property. The incumbent will have good, quality skills in the trades of rough and finish carpentry, rough-in and repair plumbing, painting and staining, small found...
Northrop Grumman Electronic Systems is seekign an Electronic Technician, Maintenance Mechanic for our Charlottesville, VA facility. Under general supervision, the Electronic Technician, Maintenance Mechanic will assist in the maintenance and repair of company property. The incumbent will have the good quality skills of an electronic technician. Responsibilities include: Troubleshoot and repair ...
Republic Services, Inc. Charlottesville, VA, 22901
With general supervision from a Lead Technician, Maintenance Supervisor, or Maintenance Manager, a Technician B performs all drive train component work (on diesel and non-diesel equipment and trucks), as well as suspension and steering systems repairs and maintenance on heavy equipment and, where necessary, can perform basic tire work, such as replacement, tire rotation, etc., and checks torque sp...
The Audi Veterans to Technicians Program provides a unique opportunity to qualified United States Military Veterans. It is designed to attract former military maintenance technicians to become brand-certified Audi Service Technicians in dealerships throughout the North American Market. Veteran candidates must meet qualifications, experience and capability requirements. The Audi Service Technician...
Sears, Roebuck and Co., a member of the Sears Holdings Corporation (NASDAQ: SHLD) family of companies, is a leading broadline retailer providing merchandise and related services. Sears, Roebuck offers its wide range of home merchandise, apparel and automotive products and services through more than 2,700 Sears-branded and affiliated stores in the United States and Canada, which includes over 890 f...
EMPLOYMENT OPPORTUNITY: CUSTODIAN Position type: Part time, exempt Reports to: Director of Production Hours: Tuesday - Saturday, 7:00 a.m. to 11:00 a.m. plus additional time as scheduled Summary: The custodian keeps the building clean and organized Essential duties: Clean bathrooms, kitchen, office space, all floors, and remove all trash on a daily basis Maintain a stock of cleaning supplies for t...
Southern States Cooperative, Inc. Charlottesville, VA, 22901
High school graduate/GED and/or related work experience. Must acquire within 30 days of employment Forklift certification. Must Have a valid driver's license and satisfactory driving record Must be able to pass a drug screen and a background check May require CDL. Requires physical strength and dexterity to walk, stand, bend, climb, reach, stoop, twist and lift/carry 100 pounds. Vision, hearing an...
Description Responsible for the pricing and signage of store merchandise through the use of equipment such as RF, Management Work Station, Laser Printer, Sign Printing Facility (SPF) and various types of paperwork and reports. The Pricing and Signage Team Member (PSTM) will also be responsible for the proper execution of pricing and signing initiatives. The PSTM is a full time position and requir...
Description Assemble or repair bicycles or ticket items for guests or for floor samples. Responsibilities: Pull the correct ticket item to be built from the storeroom racks. Read and follow Toys "R" Us and manufacturer assembly instructions, and adhere to all safety regulations for merchandise sold assembled. Assemble a bicycle completely and properly in 15-25 minutes depending on bike. Safety...
Northrop Grumman Charlottesville, VA
Description The Inertial Navigation Systems Technical Services Engineer provides technical field support on installation, configuration and training for Navigation and Maritime systems and products. They provide expertise for resolving technical problems and troubleshoot fielded systems. They provide training to customers and end users. A majority of the effort will occur at customer sites, shipy...
Lowe's Companies, Inc. Charlottesville, VA, 22901
Position Description Responsible for the overall sales and merchandise maintenance of the assigned department. Maintains the department according to company merchandising standards and store operations policies. Maximizes sales of department merchandise and related products. Ensures that all merchandising and operational activities take place on a consistent basis. Provides and ensures quick, res...
University of Virginia Charlottesville, VA, 22901
Perform skilled repair and maintenance tasks in the plumbing specialized trades area. Maintain, install and repair steam, hot and cold water boilers, and institutional plumbing systems and fixtures. Set fixtures. Respond to emergency calls to unstop pipes, etc. University Leadership Characteristics:...
Barnes & Noble Charlottesville, VA
Barnes & Noble is looking for people with vision and energy to help us in our quest to change the future of reading. We are the world's largest bookseller and one of the world's fastest growing digital media and consumer technology companies with annual revenues near $7 billion. Barnes & Noble stores average 25,000 square feet, carrying up to 200,000 titles, and servicing tens of millions of cust...
Step 7 Charlottesville, VA
Summary If you are organized, self-motivated, friendly and people-oriented,the Retail Sales Merchandiser position may be a great role for you! A Retail Sales Merchandiser, services and sells to retail accounts within an assigned territory to ensure Client standards are met and sales volume increases. The ideal candidate is self-motivated, ambitious and driven to succeed and should also have stron...
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Maintenance Career Tools
Maintenance Group Leader
$20,800.00 - $87,550.00
Typical Salary for Maintenance Group Leader in Charlottesville
Source: Monster.com Careerbenchmarking Tool
Education / Training
Some College Coursework Completed
Some High School Coursework
Source: Monster.com Careerbenchmarking Tool
Maintenance Group Leader
Assures efficient operation of the shift, including supervision of plant employees and evaluations of machine operations and maintenance.
Rate of Growth
Size of Industry in 2006:
Source: Bureau of Labor Statistics, May 2006
Meets maintenance work standards by following productivity, quality, and customer-service standards; resolving operational problems; identifying work process improvements.
Supervises maintenance workers to ensure quality completion of maintenance objectives.
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Maintenance and Repair Jobs
The stimulus plan’s strategic initiatives are expected to increase the demand for maintenance and repair workers. Learn about and search for jobs in this industry.
Production and Manufacturing Jobs
The stimulus stands to provide incentives that will benefit the hard-hit manufacturing and production sectors and create jobs. Search for jobs now.
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For writers and readers who like it dark. We talk about our horror and other dark-themed books. In-depth literary analysis of dark fiction. Conversations with authors, editors, and other industry professionals. Hosted by Lisa Quigley and Mackenzie Kiera. We have interviewed Paul Tremblay, Ellen Datlow, Josh Malerman, Grady Hendrix, and more. New episode every other Monday. Subscribe, listen, and leave us a review.
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text:
The effect of isotretinoin (Roaccutane) on serum steroids and urinary steroid metabolites was investigated in seven female patients receiving the drug for treatment of severe acne over a 16-week period. Serum concentrations of dehydroepiandrosterone sulphate (DHAS), androstenedione (A2), and free androgen index (FAI) were not significantly altered. There was a significant fall in testosterone during treatment and a significant reduction in the 24 h urinary excretion of androsterone, tetrahydrocortisone (THE) and tetrahydrocortisol (THF) from week 8 onwards and for aetiocholanolone and allo-THF from week 12 (P less than 0.05). Although pretreatment levels of urinary steroid metabolites were not abnormal, the ratios of the 5 alpha/5 beta metabolites (androsterone:aetiocholanolone and allo-THF:THF) were at the upper limit of the reference range and were lowered after treatment, suggesting that 5 alpha-reductase activity is sensitive to isotretinoin.
Rademaker M, Wallace M, Cunliffe W, Simpson NB

domain: health


BIRMINGHAM, Ala. -- Two incumbents faced opposition Tuesday in Alabama's congressional primaries, but the closest contest was expected in the 1st District, where Republican Rep. Jack Edwards is retiring after 10 terms.
Edwards endorsed former state Sen. H.L. 'Sonny' Callahan of Mobile to succeed him.
Callahan, a former Democrat who switched to the GOP after losing to Bill Baxley in the 1982 lieutenant governor's race, faced Billy Stoudenmire, chairman of the Republican Executive Committee, in the primary.
The Democratic primary in the 1st District saw Dan Alexander, former Mobile County school board president, and Frank McWright, a Mobile lawyer, fighting for the nomination.
Ron Williams, a black Mobile lawyer who represented the man who challenged Alabama's school prayer law, qualified as an independent and will face the Democratic and GOP nominees in the November general election for Edwards' seat.
Democrat Rep. Tom Bevill, who was first elected in 1966, was favored to best Mike Sharp of Gadsden in the 4th District Democratic primary. There will be no Republican opposition for that district's seat in the Nov. 6 general election.
First-term Rep. Ben Erdreich also was expected to defeat his Democratic primary opponent, Steve Arnold, in the 6th District of Birmingham. Unlike Bevill, Erdreich will have GOP opposition in November.
In the 2nd district, Republican Rep. Bill Dickinson was unopposed in the GOP primary, but three Democrats were seeking to challenge him in November.
Jack Folsom, son of former Gov. Jim Folsom; journalist Larry Lee and Tuskegee Institute history professor Willie Fulker were seeking the Democratic nomination to face Dickinson.
Lee lost the Democratic nomination to Billy Joe Camp, Gov. George Wallace's press secretary, in 1982. Dickinson narrowly defeated Camp, who decided against running this year.
Dickinson, 58, who will be the senior member of Alabama's delegation if he is re-elected, has been criticized by Democrats for taking frequent overseas trips. He said his foreign travel is necessary as the ranking minority member on the House Armed Services Committee.
Frank Tipler of Andalusia also is on the 2nd District ballot in the fall as a Libertarian.
Erdreich defeated incumbent Republican Albert Lee Smith for the 6th District seat in 1982. Smith was seeking the GOP nomination for Democratic Sen. Howell Heflin's seat in the primary.
The winner of the Erdreich-Arnold race will face Republican Jabo Waggoner of Birmingham, who served as a Democrat in the state Legislature for 17 years before switching parties this year.
Steve Smith of Birmingham, a Libertarian, and Mark Curtis of Birmingham, who is running as a Socialist Worker candidate, also qualified for the general election in the 6th District.
Democratic Rep. Ronnie Flippo escaped opposition of any kind in the 5th District.
In the 3rd District, incumbent Bill Nichols, a Democrat, will be opposed by Libertarian Mark Thornton in November.
Democratic Rep. Richard Shelby faces Libertarian Charles Ewing of Birmingham in the general election.


What’s that? It’s too early to project NFL rosters, you say?
You’re correct, but we’re going to do it anyway.
The Minnesota Vikings just finished rounding out their roster with a 12-man draft class and 10-man undrafted free agent class, giving us a complete picture of who will be attended OTAs, mini-camp and training camp.
And that means we can go through the exercise we do every year: setting a reasonable baseline for the Vikings’ Week 1 roster.
Injuries, performance and contractual situations will influence decisions along the way, but here is Zone Coverage’s first crack at predicting the 2019 53-man roster — only four months in advance.
Keep: Kirk Cousins, Kyle Sloter, Sean Mannion
Cut: Jake Browning
Would not be outlandish for UDFA Jake Browning to hop over either Kyle Sloter or Sean Mannion, but we’ll stick with the vets for now.
OFFENSIVE LINE (9)
Keep: Garrett Bradbury, Pat Elflein, Brett Jones
Cut: Cornelius Edison, John Keenoy
The Vikings are fairly squared away at center with three capable bodies, including their first-round pick. Shame, because UDFA John Keenoy had terrific analytics. Might be a practice-squad candidate.
Keep: Josh Kline, Dru Samia, Dakota Dozier
Cut: Danny Isidora
Danny Isidora will push Dakota Dozier, a free agent acquisition from the Jets, but Dozier was brought in largely because of his familiarity with offensive line coach Rick Dennison, giving him an advantage.
Keep: Brian O’Neill, Riley Reiff, Rashod Hill
Cut: Adam Bisnowaty, Storm Norton, Aviante Collins, Oli Udoh
Hard to imagine any upsets here unless the Vikings steal a center spot from Jones and give it to a developmental tackle like Oli Udoh. More than any other position, the Vikings have been consistent in going into the season with nine offensive linemen, so we’re trying to hit that number.
TIGHT END (3)
Keep: Kyle Rudolph, Irv Smith Jr., David Morgan II
Cut: Tyler Conklin, Tyler Hikutini, Brandon Dillon
We’ll take Rick Spielman’s word, for now, that Kyle Rudolph and Irv Smith Jr. will co-exist. Tyler Conklin could force his way through as well, but that spot may be better used elsewhere.
WIDE RECEIVER (6)
Keep: Adam Thielen, Stefon Diggs, Chad Beebe, Jordan Taylor, Dillon Mitchell, Davion Davis
Cut: Jeff Badet, Laquon Treadwell, Olabisi Johnson, Brandon Zylstra
I think this position should be viewed as eight players jockeying for four spots. That’s how wide open it is. Laquon Treadwell in a contract year may be released if the Vikings can’t find a trade partner, and Brandon Zylstra got hopped a little too easily by Chad Beebe last year to be considered a lock. Beebe, when healthy, showed enough to warrant another look. Then you’ve got Jordan Taylor, who has the Gary Kubiak connection from his Denver days (and pre-season chemistry with Kyle Sloter).
Finally, the Vikings have two seventh-round picks and two UDFAs with legitimate opportunities to make some noise. First gut instinct says Oregon’s Dillon Mitchell and Sam Houston State’s Davion Davis make it through after showing explosive potential in college, but again, we haven’t even seen these guys at rookie camp.
RUNNING BACK/FULLBACK (4)
Keep: Dalvin Cook, Alexander Mattison, Mike Boone, C.J. Ham (FB)
Cut: Ameer Abdullah, Khari Blasingame, Roc Thomas
Ameer Abdullah may be the odd one out now that third-round pick Alexander Mattison is in the fold. Roc Thomas could be facing suspension or jail time after being pinned with felony drug possession. Mike Boone still possesses a lot of upside after flashing throughout training camp a year ago.
OFFENSIVE PLAYERS: 25
DEFENSIVE LINE (10)
Keep: Everson Griffen, Danielle Hunter, Ifeadi Odenigbo, Stephen Weatherly, Anree Saint-Armour
Cut: Ade Aruna, Hercules Mata’afa, Tashawn Bower, Karter Schult
This is where the projections get messy. The Vikings usually keep eight or nine on the defensive line, but there’s a case to be made for 10 this season when you look at the potential of finding another roster spot further down the list. Rick Spielman mentioned Ifeadi Odenigbo by name during the draft as a competitive piece of the rotation. And with a bevy of names still on the bubble, the Vikings may want to take a flier on somebody new at the expense of Tashawn Bower in order to get more years of team control since Bower is in a contract season. Why not replace one former UDFA with another in Anree Saint-Armour?
Keep: Linval Joseph, Shamar Stephen, Armon Watts, Jaleel Johnson, Jalyn Holmes
Cut: Curtis Cothran, Tito Odenigbo
This would be a hard room to cut down to four if everybody stays healthy — another reason to consider retaining 10 defensive linemen. Jaleel Johnson and Jalyn Holmes are still promising fourth-round picks, Shamar Stephen signed a three-year contract, and Linval Joseph remains the anchor of the group. Armon Watts is a versatile sixth-round pick out of Arkansas and profiles as somebody who could contribute early on. And don’t forget about Tito Odenigbo, Ifeadi Odenigbo’s younger brother who was great at Miami last year.
Keep: Anthony Barr, Eric Kendricks, Ben Gedeon, Cameron Smith, Eric Wilson, Devante Downs
Cut: Greer Martini, Kentrell Brothers, Reshard Cliett
With Kentrell Brothers entering his contract season, the drafting of Cameron Smith feels very much like a way to get another young linebacker with a cheap four-year contract on the roster. Devante Downs also fits the bill with three years remaining.
Keep: Xavier Rhodes, Trae Waynes, Mackensie Alexander, Mike Hughes, Kris Boyd
Cut: Craig James, Nate Meadors, Duke Thomas, Jordan Martin
Suspended: Holton Hill
The Vikings prefer keeping six corners, but they’ve also shown in the past with Jabari Price (2015) and Kentrell Brothers (2018) that they are OK holding roster spots open for players on suspension. That would apply in this case to Holton Hill, who could slide back into the rotation in Week 5. For the first quarter of the season the Vikings can enjoy that 10th defensive lineman with his roster spot.
Keep: Harrison Smith, Anthony Harris, Jayron Kearse, Derron Smith
Cut: Micah Abernathy, Marcus Epps
Some speculation started Tuesday that the Vikings could experiment with Jayron Kearse — their big-nickel package specialist — as a linebacker. Until that pans out, however, we’ll keep him at safety, where he could be joined by AAF standout Derron Smith. Marcus Epps should also challenge for that final spot.
DEFENSIVE PLAYERS: 25
Keep: Dan Bailey (K), Matt Wile (P), Austin Cutting (LS)
Cut: Kevin McDermott (LS)
Usually when the Vikings draft specialists, they give them the job. Provided Austin Cutting can work something out with the Air Force to fulfill his two-year service commitment on the side, he could be the front-runner to replace Kevin McDermott at long-snapper.


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Action to tackle climate and ecological breakdown could improve the health, wellbeing, and standard of living for us all, but how exactly can tackling environmental issues help with societal health and social inequality? And how exactly can unions help with that? Following her talk for UNISON, Dr Hayley Pinto, Education and Training Lead here at the Centre for Sustainable Healthcare, is reflecting on the climate crisis and its links with sustainable healthcare.
As a way of monitoring progress many Trusts, ICBs and primary care teams are measuring and reporting on their direct emissions annually, using the BEIS Government Greenhouse Gas Conversion Factors for Company Reporting database. This database is updated yearly to reflect national changes in decarbonisation, with the most recent version published June 2023. But what does the most recent update mean for NHS organisations, and will there be any impact on their carbon footprint?
In April, the Chief AHP Officers team ran the first ever Greener AHP week, to galvanise the interest and enthusiasm of the Allied Health Professionals (AHPs) workforce to deliver environmentally sustainable healthcare as part of AHP roles. Environmental sustainability is one of the five areas of focus in AHPs Deliver, the national AHP strategy for England; it is also a priority within each of the four UK nations.
Clean Air Day is the UK's largest air pollution campaign. As one of the greatest public sector carbon emitters in the world, the healthcare sector will need to make significant reductions in order to meet its net zero carbon ambitions.
Genitourinary medicine (GUM) encompasses integrated sexual health, contraception, and HIV services. Emerging evidence demonstrates the profound effect climate change will have on GUM. Therefore it is our responsibility as clinicians to take preventative measures and transform the way we work now, in order to protect our future.
The NHS Sustainability Day of Action is quickly approaching. Over the past year, we have seen a growing number of NHS employees improve the sustainability of their practices, preserving resources for future generations while providing high-quality care.
It is National Recycle Week (17 – 23 of October)! People across the country are encouraged to recycle more often, and in the right way. Last year, approximately 82% of people were more aware of recycling methods and stated changing their behaviour following Recycle Week 2021.


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Posted 1 year ago
Jimmy Turrell’s design/illustration portfolio includes this cover for Little White Lies Magazine that was included in the magazine’s 70s film retrospective exhibition at London’s Kemistry Gallery.
Check out a close look at the work and shots from the exhibition here.
Posted on October 16th, 2011
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Construction company sues Moscow government for over $11 mln
MOSCOW, October 10 - RAPSI, Sergei Feklyunin. The court has registered an $11.1 million lawsuit filed by Glavmosstroy, a construction company owned by Russian oligarch Oleg Deripaska, against the Moscow government, the court told the Russian Legal Information Agency (RAPSI).
The company is looking to cancel investment contracts on the construction of an elite housing in Moscow.
The court has yet to set a hearing date.
Glavmosstroy PR officer Vitaly Korolyov told RAPSI that the Moscow government entered into an investment contract with Glavmosstroy and Inteco in August 2004 on the renovation of seven residential quarters in Moscow.
He added the project stalled after the Moscow authorities defaulted in their obligations. Meanwhile, Glavmosstroy spent roughly $11.1 million to complete part of its work on time.
Founded in 1954, Glavmosstroy is a general contractor engaged in civil engineering. It is a part of Glavstroy, a diversified holding company headed by Deripaska's Basic Element.


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Guilford man takes home $1.5M on $20 lottery ticket
A Guilford man is the newest member of the Connecticut Millionaires Club after winning the top prize in a scratch ticket game.
Victor Kenter bought the winning $20 scratch ticket at Express Fuels & Food Mart at 25 Mill Plain Road in Danbury.
He cashed in his ticket on April 16 at CT Lottery headquarters in Rocky Hill.
The top prize in the Connecticut Millionaires Club game is $20 million.
But Kenter chose to take a lump sum payment of $1.5 million, according to CT Lottery.
The instant game that began on Sept. 25, 2017 has five grand prizes, one that remains unclaimed.
CT Lottery says the game is is ending “soon,” but did not disclose a date.
There are approximately 4,560,000 tickets in the game.
Unlike other big winners, Kenter declined to be interviewed of have his photo taken as part of CT Lottery’s Winners Stories.
In February, CT Lottery listed a Victor Kenter, of Guilford, as the winner of a $10,000 prize on 20X Cash ticket sold at Express Fuels & Food Mart in Danbury.
It could not be confirmed if it’s the same Victor Kenter, who won the Connecticut Millionaires Club prize.
CT Lottery only discloses the winner’s name and place of residence, date of claim, game played, prize amount won, and the selling retailer’s name and location. A winner’s home or street address and phone number is never published, and will not be disclosed unless required by law.


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Barry Whistler Gallery in Dallas is celebrating its 30th anniversary this year, and it recently announced its pending move from its longtime Deep Ellum space to the Design District.
This month marks the opening of the last show in Whistler’s old space. Titled 30, it opens Feb. 13 and will feature “all artists in its current roster, as well as some highlights seen along the way,” and will include new work by Tom Orr, Ann Stautberg, John Pomara, and Linnea Glatt, among others.
After that exhibition closes in March, Whistler will make the move from 2909 Canton Street to its new location at 315 Cole Street. The gallery will work with Buchanan Architecture on the new space.
For more info, go here.
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- Five New Public Art Works For a Richardson Mixed-Use Development - December 1st, 2016
- Top Five: December 1, 2016 - December 1st, 2016
- MFAH Announces New Curatorial Fellows - November 30th, 2016
- Live a Good, Corrupt Life with the Enron Simulator - November 29th, 2016


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Please find below a curated list of 184 of The Best Lost Love Quotes by notable women and men. Please consider sharing with others any of the Lost Love Quotes that resonate.
He caught her, she fell, he caught her in his arms, he held her tightly unconscious of what he was doing. He held her up, though tottering himself. He felt as if his head were filled with smoke; flashes of light slipped through his eyelids; his thoughts vanished; it seemed to him that he was performing a religious act, and that he was committing a profanation. Moreover, he did not feel one passionate desire for this ravishing woman, whose form he felt against his heart. He was lost in love.
Grief causes you to leave yourself. You step outside your narrow little pelt. And you can’t feel grief unless you’ve had love before it – grief is the final outcome of love, because it’s love lost. […] It’s the cycle of love completed: to love, to lose, to feel grief, to leave, and then to love again. Grief is the awareness that you will have to be alone, and there is nothing beyond that because being alone is the ultimate final destiny of each individual living creature. That’s what death is, the great loneliness.


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Cicero (106-43 BC) was the greatest orator of the ancient world and a leading politician of the closing era of the Roman republic. This book presents nine speeches which reflect the development, variety, and drama of his political career. These new translations achieve new standards of accuracy.

domain: library


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Originally from County Armagh but now living and working in Belfast, Barry Kerr is one of Ireland’s most accomplished traditional musicians.
As a multi-instrumentalist, songwriter and painter he is extremely prolific in his creative output. Having recorded his first solo album at age seventeen he has gone on to tour the world both as a solo performer and in the company of artists such as Cara Dillon, Phil Coulter and At First Light. His songs and compositions have been recorded by the likes of karan Casey, Flook, Beoga, Brian Finnegan, Damian O’Kane and Kate Rusby.As a painter he is fast becoming an important figure in contemporary Irish Art,exhibiting at home and abroad to high critical acclaim.
“Growing up through The Troubles directly affected my outlook and subsequent artistic output to a great extent. It formed my opinions on social justice and equality. I expressed these opinions in my song compositions on numerous occasions.I was in turn drawn to artists who wrote about similar issues and this helped develop my own approach to songwriting.”


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Apr 25, 2022 (MarketNewsVideo.com via COMTEX) --
In trading on Monday, the ARK Innovation ETF is outperforming other ETFs, up about 2.9% on the day. Components of that ETF showing particular strength include shares of Ginkgo Bioworks Holdings, up about 9% and shares of Cerus, up about 7% on the day.
And underperforming other ETFs today is the Invesco S&P 500— Equal Weight Energy ETF, off about 5.9% in Monday afternoon trading. Among components of that ETF with the weakest showing on Monday were shares of Schlumberger, lower by about 9.7%, and shares of Halliburton, lower by about 9% on the day.
The preceding is a transcript of the MarketNewsVideo.com video published at: https://www.marketnewsvideo.com/?id=20220420220425etfotherDNAC&mv=1 .
Is there a problem with this press release? Contact the source provider Comtex at firstname.lastname@example.org. You can also contact MarketWatch Customer Service via our Customer Center.


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we love to make people think. the ability to think is the greatest part of the human experience. our work culture is based around experimentation, creativity, professionalism & client satisfaction. we are a tightly knit group of artists, directors, writers, inventors, designers, technologists, and visionaries along with a plethora of other specialists, all who bring intuitive thinking to everything we do.
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a multi faceted and tight group of creative and strategic thinkers that can solve problems from all directions. we combine all our individual expertise together to create content that tells stories.
we work to make sure that productivity is the core of every day for us. we like to work in a scenario where focus is given to the content and the final product. we love problems, specially since we don’t see them as problems, we see them as opportunities to create truly spectacular work.
If you have some interesting ideas about a collaboration, we are glad to work with you!