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Since I was a child, I always knew myself to be more different than the rest of my biological siblings. Between the ages of about 2-8 years of age, I find myself feeling sad most of the time, and harboring feelings like, “Who am I...? What am I doing here?” I always felt like I never really belonged here, both in this physical material world but also in this assigned female body (aka assigned-female-at-birth, abbreviation is AFAB). I was born a sensitive, not because I was scared, a cry baby, or that I was weak, it was because I sensed things more than other people normally would, things that were otherworldly and hard to explain as a child, like ghosts, UFOs, and the paranormal. I was undergoing early identity crisis while finding it difficult to keep myself grounded onto this world. I couldn't tell others that I can see or hear spirits, ghosts, angels, etc. because my older sister would be cruel to me and treat me like I was crazy then do or say mean things to make me cry on purpose, and told me that no one would believe a babbling crybaby. I was just a toddler who constantly was crying because I would freak out seeing entities that I knew was not among the living who would either keep following or looming over me or others around me that would simply just frightened me because their otherworldly energies were different from those who were alive and I couldn't explain it as an infant toddler to anyone. Other than that enigma of my infancy. It wasn't until about the age of eight, that I find myself disliking my being born into the female body. I remembered how I would take my shirt off, wore only pants, and pretended that a wide tooth comb was a sword while imagining I was a male samurai or a shinobi. I always imagined myself to be a boy or a man instead of a girl or a woman but back then, I didn’t know why I was feeling, expressing, or imagining myself in this way. I was told that it was not normal, uncultured, or weird, because I always played with the boys and did boy things, and therefore I was the most misunderstood, unaccepted, and have constantly been considered to be the different child in my family. As a child, my petty older sister, would bully and terrorize me, she verbally would abuse me by calling me, "The black sheep."
A back story.
Growing up was tough. My parents, specifically my father, were really strict and come from an Asian background, both with a Cambodian upbringing. My father wanted to raise us to be Khmer and would oppress all other ethnic origins that we were mixed with and often denied my mother's Japanese ways and would tease her often for nodding her head to how she sits or eats especially while utilizing the hashi (Japanese chopsticks) and often berated her for behaving too Japanese instead of being more Cambodian. He would say to her in Khmer that if it weren't for him to save her during the Khmer Rouge because of her Japanese ways, she would have been killed which was a very mean thing to say. Over the years, she gradually dropped all her Japanese demeanor. Yes, to be quite blunt, my father was an asshole! His tyranny comes from his reputation in serving the Royal Cambodian Army back in the early 1960's before the Khmer Rouge so he was very militant when raising me and my siblings. My father was into politics especially when it came to his country being a Protectorat français du Cambodge (French protectorate of Cambodia, circa 1940's), he was a member of the Khmer-French Liberal Party, he was highly educated, spoke fluent Khmer, French, and some English during his prime. He once had the French colonial flag alongside the Kampuchea national flag displayed side by side upon his estate in Phnom Pehn out on the upper verandas in his family's villa, and he even owned a French dictionary, but he was extremely traumatized by the Khmer Rouge regime that he has denied his French assuming that it triggered horrible memories of being different, non-homogenous, non-conformist, etc. He still smokes indoors, which was also a very French habit and upbringing for him.
Mixte ethnie et race!
Nevertheless, I'm ethnically mixed with Khmer-French from my father's side who is 75% Khmer and 25% French (his surname is Allaire), and Japanese from my mother's side, who is 100% Ainu, her ancestral heritage and origins roots back to Hokkaido but my mother's side of the family is quite a mystery only because my father doesn't want to hear it or let us know about it (her maiden name is Yoshida). My parents are not legally married and they both never really had any proper wedding in either of their ethnic culture as it turns out, my mother is, in fact, my father's mistress, which is very common for French men to have mistresses even when they are already married. My father had two wives, both died during the Khmer Rouge regime. His first wife was French, her name was Sézanne, which sounded like Suzanne in his Khmer-French accent, and he still displays an old photo of her in a frame at his house till this day. His second wife is Thai, to whom he has two sons with, my survived older step-brothers that occupy the Allaire's French family villa in Phnom Pehn in which my father would send money to Cambodia to rebuild after the bombing in the capital during the Khmer Rouge regime. There is no word for mistress so the Khmer wording just translates to wife. I tend to say that I'm only half Cambodian and Japanese because the French side is hard to explain but like my father, it's also a way of keeping discretion with the French side.
My father's coping mechanism from the trauma surviving the Khmer Rouge was abusing alcohol and being violent.
As a child, I remember him being an abusive drunk to both my mother, severely physically violent towards my then adolescent older brother and me when I was a toddler (about 5-6 years old), he had drowned me once in the bath tub on accident while drunk, he also had mildly tortured my little sister when she too was a child (about 7-8 years of age). You see, my father was severely violent towards my older brother and me where we both have suffered a few permanent scars, fractures, and contusions on our bodies from his drunk violent episodes. When I was turning nine, it was my broken wrist, several bruises, and marks on my body that alerted my preschool teachers where CPS stepped in and the court took custody of us. This was where and how I ended up in the foothold of my mother's homeland, Japan, where under the courts protective ruling, I was allowed to home-stay on a visa and later, had obtained dual citizenship in Japan, to live with my mother's immediate relations from the age of nine to about fourteen because my mother's older sister, my Auntie Mariko, was the only immediate contact in the United States to take over guardianship of us, since she resided in Hilo, Hawaii with her husband, aka my living-on-the-wild-side-tsunami-surfer Uncle Kazuya (whom we just call Uncle Kaz/Kazu). My father does not like my mother's side of the family and vice-versa, the Cambodian and Japanese side always clashes and there was ever only one occasion where both sides have gathered for a family funeral but it's rare to see them all in one shared or closed space. The dispute is only between my father and my mother's older sister who strongly dislikes my father.
Living in Osaka, Japan was the happiest and most Golden Moment of my precious young life!
Now, I must say, the five years of living and being raised by my mother's relations in Osaka, Japan were the best and most golden moments of my young life. However, that is another story that I will not get too deep into but I mention those parts of me because it was the upbringing and social customs that comes from both my parents backgrounds which determined how they have raised me and my siblings, as well as how growing as an LGBTQ member in the family has effected me into my teenage years especially returning back home at the age of fifteen to estranged parents, it was going back into the household of my parents in America where suddenly I find that my young sprightful life suddenly became rather dark, once again.
This is my transgender story.
Ever since we were all very little, my parents have always programmed us. They taught us how girls should behave and how boys should behave but most of the strict rules were enforced on the girls in my family. My parents made sure that the girls were more controlled than the boys in my family. I felt because of these strict rules, social-programming, social-conditioning, and control, it made me hate my female body more and the coercion into taking on this gender role as a female. I didn’t know why I was feeling this way till I hit my adult years. My two sisters hated the rules that were enforced on the girls because the boys had more freedom. They could do whatever the fuck they wanted! While the girls were taught to cook, clean, and mostly stay at home. The girls were expected to do whatever the parents tell them. The girls could not have any girl friends, no boyfriends, basically no social life, whatsoever! Due to this, my siblings and I were late bloomers as Asian-Americans growing up in the United States and I was often at times, the reclused sibling in the family and had often barricaded myself in the room until I just couldn't anymore.
My parents made sure that the girls were held in this secured box that I was so eager to break out of. We were caged!
At the age of fifteen, I realized that there was more reason why I hated being a female and I developed anger problems because I was an empath. Empaths feel everything all at once and because negative emotions is hard to cope, I couldn’t cope with negativity very well. The anger rose to a boiling point and it wasn’t because my parents enforced the gender role on us as female but it had to do with how I think and feel inside as a person about my own body and identity. I was frustrated with myself and I hated everything about me as far as I was concern. I came to realize that I preferred wearing unisex clothes and expressing myself as freely as possible to be happy. However, I realized that I belonged to a very strict and conforming household. My parents did not approve my boy short haircut because I sported a mullet and had orange dyed spiky hair. I sported multiple ear piercings. I wore a lot of metal chains and rivets that expressed my cyber punk and street goth fashion style.
My clothes were as loud and wild as the way I wanted it.
My parents decided that it was in their duty to conform me to save face. I, refused! Living under my parent's household was like a battlefield every day. So much so that my High School grades dropped and I couldn’t concentrate on my studies. I slipped into somewhat of a depression because my father took to beating me up for the way I was carrying myself on a daily basis. He made it clear to tell me how much he was embarrassed of me, that no one would love me for it, and called me, “Kathoey.” (Gay in Khmer.) It was already bad enough that some of my siblings and my peers turned against me enabling me to get bullied for who I am. There were times where the beating at home and the bullying at school got so brutal that I submitted to this act of oppression as those around me, especially my parents, forced me into female clothes. My parents took it upon themselves several times to go through my entire bedroom and throw away all my unisex clothes, accessories, my journal, photos of me with my gay and lesbian friends in which we were all dressed like boys, oh and did I mention my journal? Because my journal was therapy to me. They tore down my wall posters of J-Visual Kei bands that I admired, poster of sport cars from JDM magazines, female models from Hot Import Nights, and even my artwork with a comic book drawing that I had discreetly worked on for two years. They threw out rare omiyage (Japanese gifts) that I’ve received from my pen pals in Japan because to my parents worldviews, most of the items in my possession were too boyish.
You could imagine coming home to everything that expressed who you are, what you are, what you like, and everything about that part of you just gets destroyed by your own parents in a single day.
I got so depressed that I couldn’t really function in school and started skipping class. My grades fell from an honor roll 3.0 GPA to a 1.0 GPA. Of course, I got a physical beating for this when the school called my father to report my absences and failing grades. I got so tired of all the verbal, mental, emotional, and physical abuse, the constant oppression, and being controlled that I decided enough was enough so I resorted to running away. I begun to join a small Asian gang to sell drugs so I can buy the clothes that I wanted to wear, get my haircut and dyed to my liking, and go back to the me that I knew and was comfortable being. I never understood why my parents or other people were telling me what to do, how to have my hair, what to wear, how to behave, etc. One of my concerned teachers referred me to teen counseling and therapy because I would have mental breakdowns. During my therapy sessions, I began to admit that I was depressed as I was coping with gender identity crisis and even questioned my own sexual orientation. Along this discovery, I remember sitting at my parent’s home in my bedroom on my bed, my head was down, I felt deeply unhappy, and I remember that my two sisters were in the room with me just having a conversation when I suddenly blurted out to them, “I think I am bisexual.” I paused for a moment feeling numb saying it but I remembered asking them warily, “Would you hate me if I was?” Their reaction and response was a mere revelation, “Oh, we always knew you were different but we don’t hate you.” I asked, “But would you accept me? Because mom and dad won’t. They hate me.” They assured me they wouldn’t judge me or saw me anything less. That day, I felt comforted by the fact that at least I have two of my siblings who accept me for....well, whatever the heck I was?
I wasn’t sure at that time and was trying to figure myself out.
Later along, after many fights and quarrels with my parents, siblings, teachers, peers, and even strangers about what they called ‘abnormal ways and behavior’, my own parents and peers in school took to spreading rumors about me. My parents were saying that I was acting this way because I was a bad seed while my peers in school were spreading rumors that I was a lesbian who needed to get banged by guys to be straight. My parents convinced the school that I was a bad kid who didn’t obey them, acted out, and therefore I should not be trusted. My peers in school would send others to fight me, beat me up, and get others guys to either try to rape me or save me by trying to convert me to be straight. It seems like everyone around me were knocking me down hard but I fought them all back. I got stabbed during a cross fire gang fight in the Fillmore district and since that day I stopped selling drugs and cut ties with gang affiliations. I considered that a close call and I covered it up so well that not even my parents knew about this incident ever till this day. Since it was Chinese Triad youth gang, it was easy to slip away from this small gang unlike colored gangs like the Bloods and Crypts. I decided to lay a low profile, gave myself a nickname for safety reasons so I called myself Nicky throughout the rest of my High School years. My family never knew why I called myself Nicky but the reason why was not because I was trying to present falsehood about my name but having an alias was the only way to cloak my whereabouts so that the gang affiliations would not follow me or bring me back to their world of death and destruction. Eventually, I got my grades back up to at least a 2.0 GPA. Still, it was hard studying at home because my drunken violent father would barge in my bedroom while I am studying and he would yank my hair, or grab something to hit me with while I was trying to study. And mind, all my siblings went through some form of dysfunction, oppression, and tyranny with my father growing up but my journey or rather experience was slightly different, so for the record, my scars from it will always be different than that of my siblings.
He blamed me for everything that went wrong in the family.
One day during my therapy session, my therapist realized that I was probably an LGBT identified youth who was in the need to reach out to the LGBT community for support because I was suicidal at that time and was then considered a high at-risk youth. So one day my therapist wanted to take me to a field trip to the Castro district to watch an independent film that may answer some questions about my own gender identity and sexual orientation but being underage in High School and having to ask for parents consent, it caused another road block at that point in my life. For some reason, I thought it was a good idea to come out to my parents as an LGBT youth to try to educate them on it in hopes they would better understand me. So I tried to explain to my parents about myself but it backfired. My father got furious, ripped up the consent forms, condemned me from going to any more therapy sessions, and placed me under house arrest. This part gets explicit so if you don’t want to read, than stop reading now.
Alright, well you are still reading so don’t say I didn’t warn you.
What happened at this point in my life scarred me and probably for the rest of my life because I have never felt so much animosity from my own father that I truly believed he didn’t love me at all and went on to believing that he hated me for the next five years of my life. That same night while I was sleeping and mind you, it was a school night, he violently woke me up, dragged me out of my bed holding a pair of scissors and a baseball bat. He told me that if I didn’t listen to him that he’ll send me away. He squeezed my nipples declaring that I was a female (and well, that was the part that scarred me the most). If I didn’t knew what gender dysphoria was back then, well, in that moment I was so aware of my own physical body that my male spirit was shaken to the core because then I was hurting in my mind, heart, and soul for it and I knew in that moment that my father would never carry any contrition for me naturally being born this way. He yanked my hair and began to cut it all off and I remembered I fought back. I pushed him away. He took strong hold of my left arm and twisted it so hard that my wrist bone slightly dislocated itself. He never used the bat but he did burn my chest with his cigarette butt which left two small scars. My mother stood by watching the horror of this attack, speechless, and I knew she was powerless to do or say anything because in Asian customs, the wife shuts up and listens to her husband obediently and submissively.
I forgive my mother though. I know that this wasn’t her fault.
I thought I was having a dream where I was experiencing a nightmare till I realized what was actually happening to me and when it dawned on me that my own father is probably trying to kill me, I broke from him, and I ran! So feeling attacked, feeling like my life is in danger, with no shoes, no jacket, just in my pajamas, my broken wrist, burned chest, my hair chopped up, and in tears, I ran outside the house through the backdoor in the middle of the night as I heard my mother’s distressed voice yell out my name in Khmer from the distant, “Kan!” All I knew was that I had to get away and find safety somewhere, anywhere! So I end up running all the way to the end of John McLaren park. While I ran, jogged, and half walked out of breath in the cold, so many things rushed through my mind but mostly the strong feeling of not turning back to that hell hole called home and also wanting to just die! I found a bench and I slept on that bench, cold, sobbing, feeling numb, hoping that I do freeze to death or wishing someone other than my father would actually murder me right then and there. The following morning, my wrist was bruised and swollen, my chest had a burned scar, both my feet bled from stepping on sharp items on the bare concrete. I don’t recall how I even survived because I was so catatonic that it was as if I was not in my own body. I made my way over to a friends house and told them what happened to me. They took me to the Larkin Street Youth Center for Homeless or Runaway teens where I stayed. I’ve never hated myself for being what and who I am than in that moment. I began to resent my own father and slowly, I became bitter towards my entire family, people, and all of society that would teach the strict gender roles between boys (men) and girls (women).
For the next six months at the shelter, I suffered alone.
During that time, my older sister was my only point of contact and in some ways, it was my only solace, and that maybe my life was still somewhat significant in this world. When my parents found out where I was through my High School counselor, they played nice to me after I have made them worry for six months and wanted me to come back home to their household. I couldn’t trust them for awhile as much as they couldn’t trust me. I remember asking my parents to stop calling me names and hitting me. I told them if they promised to stop all the abuse that I would agree to come home. My parents agreed. At that point my father had already plotted some sort of reform against me by sending my aunt, uncle, and their friends to gently coerce me into changing my ways by using scare tactics. The option was, (1) either I listen to them and do as they say, (2) they send me off to Cambodia to marry some random guy and be his servant wife, or (3) they will place me in the United States Army. Remember, President Bush was elected at that time and he had declared war in Iraq. I did not want to be sent to the U.S. Army Reserve to serve in Iraq plus I have a mental health record so I probably won’t even be allowed into the army. And on top of that, at sixteen, I was considered a juvenile delinquent because my father told lies about me to the police to put me under house arrest.
It was easier for him to control or scare me to succumb to his ways.
At this point, I gave up hope and enabled them to conform me. I hid away the true me and locked myself back in the closet even after graduating High School. I dated straight guys to prove to my parents that I was heterosexual or normal but all the straight guys that I have dated were no gentlemen! I would look at how they would treat me as a female and I would tell myself, if I were a man, I would not be this narcissistic, egotistical, sexist type of guy just because I have a male privilege. In my opinion, just because a guy is born with a penis, it doesn’t make him a man. The genital parts don't make you a man! Manhood is about your character and not about what parts you have. And the way I perceive these types of guys, they were considered little boys to me instead of a grown man because they didn't act like a gentleman. I went through dysfunctional domestic violent relationships with some of these straight dudes that I have dated because I would behave too masculine for them at times and they wanted to control me with their male ego, toxic masculinity, and assert their dominant male privilege. It also goes to show that I dislike being a female and somehow throughout my early to late twenties dating straight dudes, I realized that I seem to attract abusive guys which strongly reflects the same dysfunctional relationship that I have had with my own father.
In reality, it was a reflection of the things that I did not want in my life but I wasn’t seeing clearly yet and hadn't learned how to say, "No!"
Deep within, I knew none of those straight relationships would last because that was a phase. It was not meant to be and I also knew that I would not end up settling down with a straight guy. During my college years in San Francisco, I had dated a cowardly guy who was very controlling and abusive towards me. He knew about my past and history back in High School. He would try to blackmail me to keep me isolated if I tried to break up with him. One day he offended my entire family then had the audacity to called me, my mother, and my oldest sister a bitch when I finally dumped him, he then said, “You probably acted that way because you had daddy issues.” I didn't give him a reaction because I knew that would give him the satisfaction but for the record, I strongly disagree. No, I don’t have daddy issues. I don’t have any issues. People pick on me and make me their issue. The day I realized that toxicity was also the day I chose to stop giving anymore of my time and energy to them and just focus on what I want, what I need, and most of all what makes me happy. Although, I had not realized any of that in that moment, I had continued to live my life resentfully as a female for the next fifteen years after college. Not because I wanted to... ...Not because I had to... ...It was because I was afraid and didn’t know how to be true to myself again. And for a time, I felt lost.
So when did I realized that I was transgender? To be honest, the term transgender was never known to me till now. So all this coming out (again) is still pretty recent in my life right now because to this date, I am thirty-two years old. For fifteen years, I have lived my life in oppression and I was secretly depressed. I loathed it. I failed at being a female even though I tried so hard to cover up who I truly was but those memories, those haunting moments and experience during my teen years still leaves an imprint on my soul, and it comes back to resurface from time to time. It reminds me of what and who I really am, just like a birthmark that will always be there. It was the unpleasant haunting memories of how I was bullied by my family members, ex-friends, ex-lovers, and all of the general society for being brave and true for it. Back in 2003, I was labeled cross-dresser, gay. lesbian, and dyke. Those were the terms at that time. Although, I didn’t felt like I was gay or lesbian, and I didn’t see myself as a cross-dresser or a dyke. What was normal to me was seen as abnormal to others. What made me happy had made others unhappy. What made sense to me had confused others. So when did all this nonsense stopped? It was when I looked back at the pictures of me in that male image was when I realized that now as an adult, I needed to get real with myself again. This time, no one can stop me. Not even my family. I am older now. I am free to do what makes me happy so at this moment in my adult life, I was going to do everything in my will and power to pursue it.
Realizing that empowered me to officially and permanently make the transition from female-to-male.
I was always transgender even when I didn’t know it because I didn’t learn of the term till now. In Khmer, the umbrella term is called, “Kathoey”, which equivalently translates to gay, lesbian, queer, or those who even identify as transgender. There is no specific word for it in the Cambodian language. So how did I come to terms with identifying myself as a transgender individual? Well, I was talking to a friend over Skype back in early to mid-September 2016 discussing how I felt as a female in mind, body, and soul-wise. I always felt like I should have been born male. I didn’t feel like I was gay or lesbian. I already knew that I am bisexual because I find myself to be attracted to both men and women equally but gender identity-wise, I didn’t agree with being in a female image or taking on that gender role as it did not make me happy and I felt uncomfortable being in a female body. Therefore, I felt something was missing or I felt somewhat incomplete or not whole. My friend told me to look up the term transgender and so I did. It was like huge light bulb that knocked me in the frontal lobe lighting a path, like duh! That’s it! That is exactly how I feel, how I think, and how I behave. That is what I am. There is nothing wrong with me. I wish I was able to discover this sooner but remember, I was oppressed by family members, ex-friends, ex-lovers, and the general society for fifteen years of my life. I felt it was time I came out again but this time stronger, wiser, knowledgeable, transparent, and coherent. So much more so than I ever was before because it is like this; I seriously just did not undergo through all that abuse and LGBT-related bashing and bullying to live a life how others want me to live or feed onto their preconceived notions about me on what they think of me or that they know of me to be. I realized that from then on, I will live my life authentically and I will not censor myself for anyone's ignorance.
Only I know my truth.
In late-September 2016 to mid-October 2016, I came out as a transgender non-conforming or transmasculine identified individual. As I have stated, my sexual orientation has always been bisexual. My clothes have always been unisex because I have always dressed Gothic and Goth clothes tend to be androgynous or gender neutral anyway. So it was easy for me to transition my clothing from that starting point from androgynous to later along more masculine. From there onward, in early October 2016, I reached out to a gender friendly therapist about my gender identity then eventually began my testosterone (hormone replacement therapy) in late-October 2016. My older sister came out to visit me that month so I came out to her again but this time as a transgender non-conforming individual who have decided to transition from female-to-male. She said, “...Makes a whole lot of sense because how you were in High School...You are an adult now so do whatever you want as long as it is safe and you are happy.”
From there, the journey to my hormone testosterone replacement therapy and transitioning began.
The only thing I have to face now in my life is visiting back home and coming out again to my parents and the rest of my family. I know it would be different this time around. I am grown. I am an adult. It’s not like my father has the energy to beat me up anymore. I want my family to finally see me for what I am but most of all who I am. I feel that they never truly knew me or got to know me. I am different in my family because I feel as though I would be the one in my family to test the waves of change and show them that unconditional love is everlasting than a socially programming and conditioned one especially if we all want to survive, thrive, be happy, and live a full life. As a transgender non-conforming kin in my family, I feel that has and always been my life’s purpose. I would like to let my family know that whether they choose to accept me or not that I would love them anyway. If they were an LGBT identified person themselves, if they lost their arm or leg during the Khmer rouge or endured a tragic accident that caused loss of limbs or disfigurement, if they were wretched with a lifelong disease or illness that rendered them disabled or targeted as different in society, I would still love them anyway because that is the right God-given choice to choose and do as a human being.
Life is too short to hold grudges based on diversified indifferences, petty ignorance, hate, and judgements.
I want to let them know that whether they disown me or not, that in the end, I am still of their family blood and lineage. I believe that family is not everything, that loyalty is everything, and even though blood ties can hold grudges, be petty, hate, judge, or cast off one another, new families can be found elsewhere because in the end, loyalty defines my family circle. If you are not loyal to me then you should stay away from me and leave me alone. In life, what matters is that I am alive and I am living my life the way that I want to because this is my life so I am choosing to be loyal to me now. In the end, when we all die, we take all this human experience of love and hate right back to God.
Allow me to reintroduce myself, this is my rebirth. My name is Kaneda Yoshida. I am a bisexual transgender female-to-male gender non-conforming transman. I just want to be acknowledged as a man. My gender pronouns are male, address me as he/him/his, but mister and sir would be nice too!

domain: psychology


1ST.May, 2010 was a landmark in the recent history of Rajamundry when more than 700 and odd citizens including both young veterans from legal, medical and journalistic fraternity, braved the sweltering heat to witness the unveiling of the bronze statue of Nyapathy Subba Rao Pantulu, who was considered the uncrowned king of this cultural capital of Andhra. The site where his statue majestically stands is aptly named as ‘The Hindu Square.’ Subba Rao Pantulu, a leading Advocate, freedom fighter and social reformer was also one among six others who founded the Hindu, a National daily along with KasturiAiyangar in the year 1878 to support the freedom movement and create awareness among people. This was at a time when the English Press was almost exclusively controlled by the British.
Historian S.Muthiah writes about the birth of the Hindu when it celebrated 125 years in 2003:
‘Believe it or not, The Hindu was born in ire. Six angry young men, all barely out of their teens, felt the campaign waged by the Anglo-Indian Press—newspapers owned and edited by the British—against the appointment of the first Indian,T.Muthuswami Aiyer, to the Bench of the High Court was blantantly unfair and should be forcefully rebutted. So they borrowed a rupee and twelve annas and founded The Hindu, printing 80 copies at Srinidhi Press in Mint street, Black town and promising every Wednesday evening an eight-page paper, each a quarter of today’s page size, for four annas.’
Only Subba Rao Pantulu continued to write for the paper for many years, till its Diamond jubilee in 1938. In course of an article in its Diamond jubilee number of The Hindu, He wrote (he was 82 at that time) :’As the sole survivor of a band of half a dozen young men who started the paper, I rejoice that The Hindu has completed the Diamond jubilee of Sixty years. My friends who took part in starting the paper were Messrs. G.Subramania Aiyer, M.Veeraraghavachari, T.T.Rangachari and D.Kesava Rao Pant who have not been spared to see the gloriuous position which the Hindu now occupies in the journalistic world. All of us were then members of the Triplicane Literary Society just fresh from college, and were eager to start a weekly newspaper, with the ambition of rousing public opinion and guiding it, though without any capital whatever and without any thought whether we would be able to keep it up financially and otherwise and compete with the dailies ably conducted by Englishmen. At first for a few months, it appeared in cyclostyle as a Fortnightly. Due to the encouragement of friends, we converted it into a regular Weekly in September 1878. It was soon felt that it supplied a great want and was received favourably by the Public. Shortly after, I had to leave for Rajamundry, though I continued to support the paper.”
The Hindu published a marvelous and befitting editorial on the life and times of Nyapathy Subba Rao Pantulu on January 7, 1941, following his demise.
Excerpts from the editorial:
Mr.N.Subba Rao Pantulu escaped the fate of most public men who live to a great age and whose names become ‘A legend to the younger generation’ which is often a euphemistic way of saying it knows very little about them and cares less. His magnificent vitality held good to the last and this was fortunate both for him and for the public. For he was the man who had the insatiable zest for life and an inexhaustible capacity for well doing.
“At eighty five ’’he was as active as ever in promoting the progress of liberal Hinduism and in infusing into younger men his own quiet faith in constructive work in all spheres of National life.
His ripe wisdom and judgement at the service of all who sought his counsel, and his eager curiousity in regard to all matters that had a bearing on the people’s advancement kept him perpetually young. Himself a lover of the golden mean, he could understand and make allowances for the ardour of youth. Many and distinguished as were his services to the country in the legislature, in local self government and other spheres. The The Hindu, his death comes as a personal loss, he was one of the young men who founded this journal more than sixty years ago, and to the last he evinced a paternal interest in it.
n.meera raghavendra rao


text:
He’s always a gentleman, and even in the face of rumors that he’s gay, George Clooney maintains his composure.
The “Ides of March” star told The Advocate that he’s not shaken up by the continual claims that he’s in the closet about his sexuality.
“I think it’s funny, but the last thing you’ll ever see me do is jump up and down, saying, ‘These are lies!’ That would be unfair and unkind to my good friends in the gay community.”
“I’m not going to let anyone make it seem like being gay is a bad thing. My private life is private, and I’m very happy in it.”
Clooney added, “Who does it hurt if someone thinks I’m gay? I’ll be long dead and there will still be people who say I was gay. I don’t give a s**t.”
Photo Credit: Getty Images

domain: celebrity


text:
4pm - 9pm
Each Wednesday, Friday and Sunday night, treasure hunters, bargain spotters and after-dinner walkers make their way to the Surfers Paradise Beachfront Markets to wander along the coastal stretch.
With more than 120 market stalls, live entertainment sets and a cheerful mood in the gentle ocean breeze, the Surfers Paradise Beachfront Markets feature a variety of premium and unique products, including fashion, jewellery, accessories, artworks, photographs, beauty products, home wares and services.
The Surfers Paradise Beachfront Markets have been operating on the Esplanade at the end of Cavill Mall, Surfers Paradise since April 1995. During this time the Beachfront Markets have become a Surfers Paradise icon that provides a unique shopping and cultural experience, and continues to be one of the top things to do on the Gold Coast, capturing the city’s laid-back lifestyle right along the iconic Surfers Paradise foreshore.
The ideal destination for gift shopping with a difference, where visitors can discover all sorts of unusual and one-off pieces, with friendly stallholders always on hand to chat about their wares and the often-fascinating stories behind them.
The Beachfront Markets also hosts several talented artisans-at-work and fun attraction stalls, ensuring visitors of all ages remain captivated by all that is on offer.
Make a night of it and visit one of the many restaurants and cafes, and have a truly magical markets night!
Click here for more info.

domain: travel


Founded in 1876, R.STAHL TRANBERG is a world class provider of smart marine applications, explosion protection and systems safety to the oil & gas, marine and industrial sectors. High product quality and durability have been developed through delivery of equipment to the demanding maritime and offshore markets for the last 100 years.
The company produces:
• Navigation and signal lights
• Navigation light controller
• Helideck lights and windsock
• Junction boxes
• Cable glands
|Floodlight in stainless steel for the Arctic environment. Also available in EEx d in aluminium housing.|
Tranberg appliances primarily utilize brass, aluminium and stainless steel. Products in 316 stainless steel are playing an increasingly important role in offshore and marine installations. All products are made to withstand adverse weather at sea, and signal lights, junction boxes and cable glands are available in explosion-proof models for installation in hazardous areas.
Navigation and signal lights can be controlled from a panel. Tranberg control panels feature rugged solid-state components and simplified operation, ensuring reliable lamp operation.
Built in brass and stainless steel for rough environments. All lights include connection box and cable gland.
COMPLIANCE & QUALITY
Tranberg navigation lights comply with all relevant SOLAS and IEC requirements. The company’s quality assurance system is certified by Det Norske Veritas (DNV) in accordance with NS-EN ISO 9001.
Navigation lights with 20 year warranty. Reliable, safe and cost efficient. Navigation light controller with backlight and external connections.
Export Markets Tranberg exports its products around the globe and has representatives worldwide.


SYN-FAB signs strategic distributor agreement with
Mobile, AL – March 15, 2021; SYN-FAB, a manufacturer of High Temperature and Industrial Process Monitoring Systems, announced a strategic North American distribution partnership with Sintrol (Helsinki, Finland).
SYN-FAB is an American-owned, technology-based company with a strong background in Thermal Imaging and High Temperature Industrial Process Monitoring applications. With a 47-year history in engineering, designing, manufacturing, and selling high-temperature imaging and monitoring solutions, SYN-FAB is uniquely qualified to offer the best possible customer service and post-sale support for Sintrol Dust Monitoring solutions.
The new partnership is expected to expand Sintrol’s globally proven innovative dust monitoring solutions to the North American market.
Sintrol manufactures high quality, low maintenance Dust Monitors for the detection and monitoring of combustible dust concentrations. Sintrol with their 30+ year experience, coupled with their engineering department, take pride in delivering application specific solutions to their customers. Sintrol’s mission is to solve customer challenges with safety, regulatory compliance, environmental responsibility and profitability. Sintrol provides dust detection solutions for emissions monitoring, filter leak detection, as well as ambient dust monitors. Sintrol’s primary focus is to be the world’s most trusted and reliable dust monitoring solution supplier.
Typical industries include food & pharma, power, cement, metallurgy, chemical, feed, – flour & sugar mills, pulp and paper among many others.
Michael Kennedy, +1 251 510 2300, firstname.lastname@example.org
Bryan Pape, +1 251 680 4372, email@example.com
John Korpi, +358 50 463 5452, firstname.lastname@example.org
7863 Schillinger Park Road
Mobile, AL 36608
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text:
& Market Trends
Posted May 2, 2011
“What goes around… comes around” is an old adage with common sense logic. It’s just perfect karma for those with an affinity for the concept of eastern thought. However, if this simple cliché means you got what you deserved and justice prevailed, the Federal Reserve has a lot of explaining to do to the American people about the depreciating dollar that, according to the Fed, boosts exports and helps the economy. As a humble student of central banking, I have come to realize it has never occurred to Ben Bernanke that zero interest rates forever (plus QEI and QEII, adding $2 trillion to the Fed’s balance sheet), might do more than just depreciate the dollar.
According to figures compiled by the United Nations, the cost of food worldwide rose 37 percent from February 2010 to this year. You may also have noticed in the news lately that rising food prices have toppled Arab governments around the Mediterranean, and scared Chinese leaders lily white as they face strikes and the nightmare of possible revolution. If only our central bankers could think differently about money printing and the hazards that have resulted because of it. When I fill up at the gas pump now, I can see the inflation from easy money that boomerangs right back at me as I contemplate putting in regular gas (up 30 percent over the past year) rather than a higher grade, which my car calls for.
Boomerang inflation is a weapon that works like this: While the Fed sits back and prints more money like there’s no tomorrow, higher food prices are created worldwide. Some countries have been so badly influenced by rising food costs that their citizens are fighting back by rioting in the streets. The Saudi royal family, not wanting to lose their country to “dumb-ocracy”, had to bribe their citizens with another $150 billion a year in handouts to avoid riots and revolution. The price that America will pay to keep the Saudis running Arabia is a higher oil price. (In order for the Saudis to balance their new government budget, they need oil at over $100 a barrel.) So, by printing too much money, America has effectively been put over a barrel.
The Chinese economy, in the meantime, is feeling the heat as rising food and fuel prices have put incredible pressure on their economy. The government was forced to raise the minimum wage by 20 percent last year and then again this year by another 20 percent. The combination of 10 percent real growth and higher wages has added to the world demand, resulting in budget busting gas, food, and raw material inflation as evidenced everywhere in stores around the globe.
What’s coming next is the inflation boomerang ricocheting back to America accelerated by China’s vicious wage price spiral. Chinese truckers are blocking ports and other workers are striking because they are getting crushed by the rising cost of fuel and food. The government remains afraid of yet another political upheaval reminiscent of the Tiananmen Square protests which rocked China’s leaders to their core as people stood up to the government. It’s highly likely that the leadership there will cave in to the people, rather than be trampled by them, as the unrest continues to build.
Inflation in America could fluctuate even higher due to a big shift in China’s policy of holding their currency down against the dollar. A rising Yuan helps them absorb rising commodity prices, and letting the Yuan appreciate is the last big change they can make to hold back domestic inflation and pray they don’t have riots and demand for political change. A rising Yuan and higher wages also make Chinese workers more competitive with Americans for scarce food and fuel, pushing up their prices even further. China has 1.3 billion people to feed and clothe (a billion more people than America) so any increase in the Chinese currency and wages influences the demand in a very big way for commodities, input costs, and goods America must import. It’s sad but true that stores like Wal-Mart can’t buy American-made goods because it seems we don’t make them anymore.
So, how is the American consumer really influenced by the Fed’s policies of money printing and a falling dollar? In the past few months, the CPI has risen while disposable income has fallen at a five percent annual rate. This is equivalent to putting on a five percent national sales tax. Moreover, if inflation is just measured by the cost of necessities, the cost of living is rising at 10 percent a year. (See: shadowstats).
The current generation is about to learn firsthand what stagflation feels like. With prices rising faster than incomes, and the real standard of living going down, the only thing that has “Made in America” stamped on it is our inflation boomerang balanced by karma coming right back at us. If what goes around comes around – and boomerangs are known for returning to their point of origin – Fed officials should take duck and take cover as an angry public gathers and begins to throw pies in their faces at press conferences after FOMC meetings. (The new press conferences are, of course, being organized to try to convince Americans that the massive inflation is not
the Fed’s fault).
During the recession we were told that unemployment was the biggest threat, but now it’s becoming clear to hard working Americans that with the Fed’s soft dollar, they won’t be able to buy a tank of gas to drive to work. The central bank itself is now becoming the biggest threat to the average American.
Apr 28, 2011
Finance Group, LLC
2505 S. Ocean Boulevard
- Suite 212
Palm Beach, Florida 33480
Richard Benson, SFGroup, is a widely-published
author on securitization and specialty finance, and a sought after
speaker at financing conferences on raising equity for mid-market
Prior to founding
the Specialty Finance Group in 1989, Mr. Benson acted as a trading
desk economist for Chase Manhattan Bank in the early 1980's and
started in the securitization business in 1983 at Bear Stearns,
and helped build the early securitization businesses at Citibank
and E.F. Hutton.
Mr. Benson graduated
from the University of Wisconsin in 1970 in the Honors Program
in Math, and did his doctoral work in Economics at Harvard University.
Mr. Benson is a member of the Harvard Club of New York and Palm
Finance Group, LLC is a Florida Limited Liability Company and
is registered with FINRA/SIPC as a Broker/Dealer.

domain: finance


text:
Deevynovel fiction – Chapter 717 – A Part Of Fate collect realize share-p3
Novel–Dragon King’s Son-In-Law–Dragon King’s Son-In-Law
Chapter 717 – A Part Of Fate addition strange
the mother and her child is/are
She always noticed unexplainable to Hao Ren, so he didn’t dare to deal with her being an common attractive female. Also, he didn’t dare to cover factors from her.
It sounded like Lady Zhen didn’t want Hao Ren and Su Han to walk around this palace randomly. She also didn’t wish to independent Hao Ren and Su Han into several spaces.
“Nevermind. Qiong Qi is actually robust for yourself fellas to cope with. You folks will go rear,” Woman Zhen waved her hand.
“You people can relaxation here for a little. This is the great spot for cultivation. I will come to you men if there’s everything.” Woman Zhen withstood up elegantly and said to them.
Which meant… the crimson golden hairpin which was on the cave entrance that night… in the middle of loaded free of moisture woods and swaying bonfire…
Woman Zhen was thankful to always be resolved as Auntie by Hao Ren. Hao Ren was the blood brother of Zhen Yuan Zi, but he still dealt with her as Auntie. In this situation, her status was greater than Zhen Yuan Zi’s.
Afterward, she walked to Hao Ren and Su Han and applyed them some teas with an unwilling term.
Dark tights wrapped around her longer thighs. Although those weren’t the lengthy robes for farming, her pose still checked beautiful.
“I prefer to snooze,” Hao Ren looked over her and said.
Duan Yao immediately needed a pot of water in the maid outside when she spotted Woman Zhen sitting down. Then, she delivered into the space and put some tea for Girl Zhen.
The nature basis strength at the center of the Demon Water was greater than any places that Su Han ended up being to. Absolutely, she were required to cultivate effectively along with her time.
Certainly, this kind of laugh quickly experienced her mind. She wouldn’t retain the reputation to themselves. The actual reason that she was pleased was that Hao Ren didn’t set up an att.i.tude thanks to his a.s.sociation with Zhen Yuan Zi.
Perhaps the Heart and soul Growth Realm cultivators and Divine Dragon couldn’t type in this center place of your Demon Ocean, but Hao Ren and Su Han were definitely fortunate to find out this by using Young lady Zhen!
“Yes, Queen Zhen,” each maids saluted towards Girl Zhen.
18 sun rays of lighting taken from a yardage.
Hao Ren reached out his biceps and triceps and hip and legs, moving himself about the mattress and didn’t wish to transfer ever again. His characteristics substance was recovered through Zhen Yuan Zi’s Immortal Fruits. Nevertheless, his human body which had been almost destroyed by Qiu Niu still experienced serious agony.
Young lady Zhen didn’t request Duan Yao to sit down she let her take a position deliberately to field her a touch more.
The Corner House Girls Among the Gypsies
Duan Yao who has been practicing sword techniques before the Taichi Palace saw Lady Zhen and ran toward her quickly and happily.
“There’s no problem that you simply males like each other well.” Young lady Zhen reduced her head slightly and sounded like she was in a despair state. She recurring the phrases that Zhen Yuan Zi stated well before, “The experience of affinity obtained pa.s.sed…”
“How was the combat on the Nine Dragon Palace?” Girl Zhen found the teacup and blew about it to amazing it decrease as she required Hao Ren.
Yet, in Young lady Zhen’s territory, she was tame for instance a bunny. Immediately after Woman Zhen sat down, she immediately applyed her herbal tea. If Lady Zhen seemed slightly depleted, she would make the effort to ma.s.sage her thighs and shoulders.
Which meant… the purple gold hairpin which was with the cave front door that night… in the middle stacked dry out forests and swaying bonfire…
She was using an extended pinkish skirt and appeared slender and very. Beneath the lights on the magnificent palace, she looked being a little Girl Zhen.
The Diva Runs Out Of Thyme
Because a little small bit of Girl Zhen’s heart feels continued to be on the purple rare metal hairpin, then Lady Zhen probably realized anything that Hao Ren and Su Han came across.
“Yes, Princess Zhen,” both maids saluted towards Lady Zhen.
Duan Yao was Lady Zhen’s disciple, and Su Han and Hao Ren had been Woman Zhen’s guests. In this situation, her condition was already under their own. Unless of course Lady Zhen required her to sit down, she wouldn’t sit down presumptuously.
The exterior town, the inner area, the safety the wall surfaces, the noble palace…
“Um…” Young lady Zhen heightened her hand and yawned lazily as she asked, “All completed?”
It sounded like Duan Yao was developing a very good existence on the Demon Ocean, and Woman Zhen did actually cure her effectively.

domain: literature


text:
I’d like to announce the publication of the Fall 2014 issue of Ray’s Road Review, featuring a lot of great new fiction, nonfiction, and poetry. This issue also marks the passing of the nonfiction and photography editing baton from Kelley Clink to Gretchen VanOstrand. Many thanks to both women.
Since I edit the poetry, I may as well plug the poets in this issue. They are Carolyn Ogburn, BZ Niditch, Ruth Z. Deming, Marcella Benton, Tamer Mostafa, and Erren Kelly. I hope you enjoy their work.


text:
Post about what is a defining game.
I was listing to a podcast, Ign’s game Scoop! while i was meant to be studying. They were taking reader questions and the one that got my attention was “What is the game that defines this generation?” while i think that the Scoop boys discussed it well, i do think they missed what this generations defining game’s were, not game. During this segment they do bring up the fact that there really is no one defining game of this current cycle of console, though they don’t ever really say what those defining games are. they mention games in passing like Minecraft and Call of Duty but there never really decide on what was the defining games of this generation.
I don’t really blame them for not deciding on what games defined this generation and both of the two they mention in detail were good examples, but i don’t think that it was just these two games the defined this the 7th generation of games. So first we must ask How? how do we define a Defining game ? What is a defining game? What must it do to be a defining game?
I think a defining game must do one of 3 things.
1. Influence other games of this generation, weather its a singular gameplay mechanic or an art style. This should be traceable to the first game executed on these with shear perfection. For example mario 64, this game was the bench mark for any 3d platformer to come out during the 64 bit era of the n64 and PlayStation. as well as influencing games like crash bandicoot and rayman 2
2. It should have a lasting impact on the player. This could be things like how it plays, the games story, its art style, the characters. examples from the past include Zelda ocarena of time, mario 64 and doom.
3. It should still be playable. This one is rather important, if a game is still fun to play after like 10 years then it has succeeded as a defining game. i am basing this off the idea of classic movies, most classic movies are still extremely watchable now. practically anything by Alfred Hitchcock can still be watched and enjoyed by anyone who likes films. so why not apply this logic to games as well.
So now we have some definition to what a defining game should be, we can now apply this to a variety of games that came out this generation. So my first choice shouldn’t surprise anyone.
Gears of War
On November 6th 2006 the game that brought the world chest high wall with the ability to magnetically attract big manly rectangles was unleashed on to an unsuspecting world, becoming a big hit with commercial audiences and critics all over the world. Gears of war made the gameplay idea of third person cover based shooting popular with gamers, a gameplay mechanic that would appear in hundreds of games this generation like uncharted, mass effect, inversion and many more. Any game that came out this generation that had third person shooting was compared to Gears of War and its subsequent sequels, this being a testament to its well designed levels and thought out gameplay mechanics.
Call Of Duty 4: Modern Warfare
Call of Duty is arguably the Biggest Franchise in the world right now, its the only game franchise to have a single game to exceed sales of 1 billion dollars in only six weeks. its a well known brand by the hardest of hard core gamers to casualest of casual gamers. it dominates sales charts all over the world and has been the best selling games of the year for the last 3 iterations. its a pop culture phenomenon, but why ? it started way back in 2005 the creators of the call of duty franchise infinity ward saw that the genre of first person world war 2 shooters was becoming over saturated with title after title being released to less then critical acclaim and mediocre sales. so what did they do? they passed off making the third game to a lesser known studio and went in to hibernation for about a year and a half then it came out and dominated an area only halo had really been playing in.
No body saw it coming, this game blew peoples minds. Even thought battlefield 2 had come out 2 years early fans and critics were stunned and amazed but the radical jump from world war 2 to the present day is something that would help influence many games like medal of honor and battlefield. This modern military shooter didn’t just define where war shooter would be set, it also set the standards for this generation of online mulitplayer and linear story telling. It was the first FPS game to make use of an xp leveling system as a hook for its multiplayer, something that is now something every multiplayer game has to have or else it feels uncompleted. It began to make publishers feel that there game had to have a multiplayer component even if they didn’t need one, they did this so they could so they could compete with call of duty. if that isn’t and example of a defining game then i don’t know what is.
Mass Effect Trilogy
So this one isn’t really a single game, evident by the fact i use the word trilogy in the title. But i digress. Mass Effect is probably one of the games that will be talked about for ages, not just about its polarizing ending, but that it did something that no other sci-fi game/tv show/moive/book hasn’t done in a long time, not since star wars or star trek. It established an amazing fully realized universe. The fact that a good chunk of mass effect universe was squeezed in to the three games with things like visual story telling, journal entries, audio logs and an expansive narrated encyclopedia that was expanded and included in all there games. ￼ If anything each games theoretically contains over 100 books worth of story’s and general lore, but the fact they included it all in to just these 3 games (not including the books, comics and other side games) is freaking impressive.
it doesn’t end there though, there another reason why i think the series as a whole help define this generation was its story. The story in mass effect was truly epic in every sense of the word, It was the first game to my knowledge to make you choices effect the subsequent games giving the player some sort of owner ship of not just a character but an entire universe. People became attached to the universe that was shaped by them, i certainly was. it was a feeling i never had in a game before, i was in control of what could happen to a thought to be extinct alien race, i had the power to remove religion from a race of sentient robots, i had the power to decide if one race would be allowed to bread again! That’s only just a small selection of what was possible and some of them were not even main story quests!!! just that power alone made this game so engaging for me and many other out there.
So that’s it, these are some of the games that i personally think defined this generation. I am completely aware i have missed some games and you can tell me all about it in the comments or not, but these games have had the biggest impact on this generation of consoles. People are going to remember these games and the games they gave birth to. Even if you disagree with me, you know im just a little right.

domain: entertainment


text:
Exceptional fine art prints
We print all our posters using Lucia Pro technology with 12 original pigment inks.
With ink droplets as small as 4 picolitres (that's 1,000,000 times smaller than a raindrop) our posters are of the highest possible quality.
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- Posters sold without frame . You will find the frames here
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The Gizycko poster is a continuation of the new mini-series "Poland is beautiful". The series aims to present more or less famous tourist destinations in Poland.
Giżycko is the undisputed capital of Polish sailing. It is located in the central part of the Masurian Lake District in the Land of the Great Masurian Lakes. It lies picturesquely sandwiched between the Niegocin and Kisajno lakes. During the summer season Giżycko is besieged by sailboats glittering in the sun and tourists in love with Masuria.
Therefore, we symbolically wanted to show what is most characteristic in the scenery of this summer town. A sailor sailing alone on the lake on his sailboat and the water sparkling in all shades of blue.
GIŻYCKO poster is the work of Poznan artist Katarzyna Nowakowska. It was made especially for our order. See also other posters from the POLAND REGIONS series in our gallery.

domain: geography


text:
Covestro entered into a global revolving credit facility for general corporate purposes and as a liquidity reserve. Syndication took place within the Covestro core banking group.
The multicurrency revolving credit facility of 1.5 billion euro is due in September 2022. Predominantly, the facility serves as a liquidity reserve. Furthermore, the facility could be used for financing peaks.


text: In October 2009, the Advisory Committee on Immunization Practices (ACIP) approved a newly licensed vaccine, Cervarix, directed against human papillomavirus (HPV) to prevent cervical cancer. The ACIP also expanded its recommendations against HPV by giving permission to physicians to vaccinate males aged 9 to 26 years with the previously licensed vaccine, Gardasil, to prevent genital warts, in addition to its previous recommendation for females aged 9 to 26 years to prevent cervical cancer and genital warts. The marketing, expense, safety, and reactivity of Gardasil continue to be the subject of controversy. Of the >100 types of HPVs, approximately 40 are sexually transmitted, and HPV is the most common sexually transmitted disease. By age 50 years, 80% of women will have contracted a sexually transmitted HPV infection. While most individuals are clear of infection by 2 years, some types of HPV carry a high risk for progressing to cancer, and HPV is identified in >99% of patients with cervical cancer. Each year in the United States approximately 12,000 women develop cervical cancer and nearly 4000 die of it. Human papillomavirus is also associated with genital warts and other anogenital cancers. The United States has now licensed 2 vaccines against HPV, Gardasil and Cervarix. Gardasil has been shown to be safe and effective in preventing HPV infections by types 6, 11, 16, and 18; types 16 and 18 are associated with 2 high-risk types of cervical cancer and are associated with 70% of all cervical cancers. Types 6 and 11 are associated with 90% of anogenital warts. Cervarix has also been shown to be safe and effective in preventing HPV infections by types 16 and 18, but offers no known protection against anogenital warts.

domain: medical


text:
Article updated 2018
I will start with a definition of depolarization: To partially or completely eliminate or counteract the polarization of.Â Where on earth does this word come from and what does it mean in the context of your relationship with men? Most men and women, regardless of what they’re showing up as, have a sexual essence that is more typically associated with their gender. So, most women will be feminine at their core, and most men will be masculine at their core.Â (Click here to take the quiz “How Naturally Feminine Am I Actually?”)
There are women who are more masculine at their core, and there are men who are more feminine, naturally, at their core. However, most men are more masculine, and most women are more feminine. Frequently what happens is that women in this modern day are more masculine now, and men are more feminine. Because of how society has changed throughout history, the roles of women and men have changed greatly. Our job here is to recognize this big change and the negative effects that it may have on our relationships, and truly honor the differences between the sexes! (read my article about are you a feminine, masculine or neutral)
Let me just confirm: I am not encouraging manipulation. This entire site is about helping women become better women, and to embrace more of who they are and bring out more of what they embody at their core.
The Truth is, lovelies, the vast majority of women are making HUGE, and often somewhat irreversible mistakes with men! The men may not even know what on earth has caused them to feel sour towards the woman, as we are so out of touch with our personal identification of our sexual essence at our core, that most men don’t really know what is actually going on consciously, but they know they don’t want to be with that woman. So, the relationship fails. Or the marriage fails. Many relationships lack passion, depth, closeness, respect, understanding and worship. I am aware that worship is a strong word, but wouldn’t you like to be worshiped by your man? I will talk more about worship in later posts. Back to the main point.
ONE of the ways in which depolarization occurs, is when the woman (or man) does things that take away from the other person’s sexual essence. For example, one of the core differences between masculine and feminine is that men are driven byÂ direction in life, and women are driven by emotion.
What Is The One Specific Emotional Trigger Within Every Single Man in this World That Inspires Him to WANT to Commit to One Woman, Want to Take Care of Her, Worship Her and Only Her? Click here to find out right now…
– Question whether he knows where he’s going whilst driving, or getting frustrated that he appears lost, or getting angry at him for it and even exclaiming that you’re late because of him, or rolling your eyes. This hurts a masculine man deeply. (read my article about how to comfort your man)
– Suggesting you call a mechanic to help him with the car when he is diligently trying to fix it himself!
– Suggesting he ask somebody for directions
– Ridiculing his goals and dreams
– Not supporting him with his goals and dreams
– Mentioning his failures to get that job, get the raise, get that promotion, get that degree
– Making him wrong
– Telling him how his ideas/opinion is wrong (boy, have I made this mistake before!!)
I think we have all made a couple of the above mistakes, if not all. The problem with doing the things I have mentioned above (and there are many more examples of ways that women destroy the polarity in a relationship with their man) is that the woman has just destroyed the polarity between her and her man.Â (Click here to take the quiz “Am I Dating a Commitment Friendly Man?”)
Polarity is the quality of opposites/opposing energies in your relationship. Polarity is an essential, IMPORTANT ingredient to have in your relationship if you want it to last. And last with passion, love, commitment and desire.
One quick way to rectify the situation is to say ‘oh yes! You are right about that, how come I didn’t think of that?!’. You don’t want to be insincere. However, if he does have a point, at least acknowledge this to him and maybe ask him for more of an explanation. You’ll find it much easier to connect with him, rather than ending up in a painful argument that doesn’t serve either of you.
As his woman, the worst thing you can do is to somehow imply that he is wrong. A fast way to build up resentment in a man who has a masculine sexual essence is to tell him he is wrong. Reverse the situation, and a fast way to build resentment in a woman with a feminine sexual essence to to tell her she is ugly. Also, if by any chance another woman somehow gives your man reason to think he’s right, and to feel more of a man, he’ll start associating more positively with her instead! This is what happens when you do not fill your man up/meet his needs. (read my article about he says he misses me)
To succeed with men/a man, you must learn to be the woman he can count on for support. The woman who gives him reasons to feel like he is a MAN when external things are pulling him down. You must be the internal link to his core sense of masculine identity. You must have the quality and understanding of femininity as well, and the distinction between the sexual energy of the sexes. If you look up to him and admire him and truly believe in him, it’s going to be hard to find another woman to take your place, lovely!
Often what happens in relationships is that the woman is so unaware of this that she destroys not only the polarity and the core sexual energy between them and therefore the PASSION, and that she slowly but surely destroys his masculinity and sense of identity. He will lose hope. And YOU will start to lose respect for him, because men who have lost hope or lost the ‘fight’ in them often let women walk all over them. Let’s face it, no woman truly respects a man that lets her walk all over him. Most – if not all women want to be led and taken cared of by their man.
Lots of women are actually digging their own grave, and don’t really understand why.
By the way, I’ve just published my brand new DVD titled “Becoming His One & Only!”… and right now it’s FREE for you to get a copy. Click HERE to find out more details and how you can get your man to fall deeper in love with you and beg you to be his one and only
I guess all of us have many questions about men, like why do men pull away? This is just one of the questions answered in our program Understanding Men. Click here to find out more about this program and earn a degree in Understanding Men in 2 weeks.
Any thoughts, suggestions or anything, feel free to share!
P.S.Â Connect with me on social media.
TheRedArchive is an archive of Red Pill content, including various subreddits and blogs. This post has been archived from the blog The Feminine Woman.
|Title||Mistakes Women Make to Destroy Sexual Polarity with Men|
|Date||February 2, 2010 6:31 AM UTC (13 years ago)|
|Blog||The Feminine Woman|
© TheRedArchive 2023. All rights reserved.
created by /u/dream-hunter

domain: sociology


- Special Features
Blogs & Columns
- Fun & Games
Twilight star Nikki Reed and American Idol star Paul McDonald are headed for divorce after two years of marriage.
According to People, a representative for Reed confirmed the news in a statement, “After much consideration, Nikki Reed and Paul McDonald are ending their marriage. They have been living separately for the past six months due to work obligations.”
Reed, 25, and McDonald, 29, plan to continue their professional relationship as they finish their debut album I’m Not Falling.
McDonald and Reed met at the premiere of Red Riding Hood in March 2011, according to Daily Mail. They said their “I dos” seven months later.
Last October, Reed spoke with people about balancing her demanding career and marriage.
“It’s important to communicate and stay on the same page. With what we do for a living, its important we make each other know they come first,” said Reed.
The actress has been preoccupied by three movies that will be presented at the TriBeCa film festival.


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Why Cardio Screening Is a Must!
Cardio Screening, also called heart testing, is a diagnostic method utilized by the medical care market to gauge the efficiency of the heart in pumping blood. This easy, fast, non-intrusive test will expose essential information of the heart such as: Pulse recognition to precisely determine any problems in your ventricle’s heart beat; ECG type reading; and also your cardiac result analysis. Testing examinations are carried out previously, throughout, as well as after exercise training programs along with during as well as after pregnancy. This is necessary for individuals who regularly take part in high-intensity workouts. This is likewise vital for those who have various other health issue such as heart issues, diabetes mellitus as well as high blood pressure.
Heart disease is one of the leading causes of death in America today. While being tested for different conditions, cardio screening often reveals many non-threatening conditions that can be dealt with and also also avoided. Inappropriate treatment commonly leads to additional difficulties. Early evaluating for high blood pressure can prevent a cardiovascular disease; as well as early testing for high cholesterol can protect against a stroke. Early testing can also result in fat burning, lower blood pressure as well as reduced blood cholesterol.
Cardio Screening can aid identify whether or not you have a heart disease. There are numerous sort of cardio screening that can screen for different sorts of diseases. The very first kind is an Exercise Heart Rate Monitor. This little device documents the heart rate during exhausting exercise without revealing the specific any details that would allow the surveillance of the heart’s rhythms. A breast x ray can be used to determine whether or not a cardiovascular disease exists. These examinations are not 100% precise and also do not lead to a total heart history of the person.
One more kind of cardio testing is the reading of oxygen saturation of the blood stream. Oxygen saturation of the blood reveals the quantity of oxygen exists in the blood as a percentage of the total quantity of blood that is included within the body. High degrees of oxygen may show a major clinical problem such as a heart trouble or a kidney condition. High degrees of carbon monoxide can additionally suggest a significant condition. Carbon monoxide gas is created from the burning of fuel in vehicles, yet can be soaked up by the body via inhalation.
Digital Doppler modern technology is one more form of cardio testing. An individual undertakes a collection of common examinations that reveal much stress and anxiety on the arteries and heart. Throughout the test, the Doppler produces a sound wave that is listened to by the individual as he or she strolls, misses, jumps, or bumbles. The regularity and stamina of the acoustic waves are very correlated with just how much tension is being placed on the arteries. On top of that, the Doppler can likewise determine the heart rate as well as blood pressure of the subject.
A a lot more sophisticated kind of cardio screening is the cardiac catheterization. An unique stent is put in the person’s groin location to place a catheter tube right into the circulatory system and also to keep track of the oxygenated blood versus the pressure of the blood being pumped by the heart. The price of the heart is kept an eye on through the stent for changes in the electrical existing as well as to establish if the heart is pumping sufficient oxygenated blood to provide the body. Some kinds of cardio testing do need the use of a specialized pump; most call for the use of a finger pulse monitor.
There are lots of various other ways to obtain screened for cardiovascular problems, including via ultrasound and also magnetic resonance imaging. These kinds of examinations give detailed info about the heart, lungs, and kidneys without calling for the person to undertake invasive treatments. It is necessary to receive these types of cardio testings on a regular basis in order to stay healthy and balanced.
Several health care experts suggest routine cardio screening a minimum of once a year. This can assist to identify potential cardiovascular disease risks in addition to to detect the beginning indicators of feasible strokes or other clinical problems. The advantages of cardio testing typically exceed the advantages of the intrusive treatments utilized to screen for cardiovascular problems. Therefore, many people find that executing non-invasive examinations rather than obtaining intrusive procedures, such as electrocardiograms or sclerotherapy, is the very best means to remain healthy and balanced.
What Sort Of Stroke Testing Tests Prevail?
Stroke testing is really vital in the therapy of stroke, specifically when the stroke is triggered by a blood clot in the capillary. Embolism that formed in a capillary are referred to as “apoplexy.” An embolism can be caused by anything: an automobile crash, a cold, or perhaps a stroke. Stroke is serious, and also if it is captured early sufficient, stroke testing can conserve your life. Evaluating for embolisms is done mostly with blood examinations and electrocardiograms (ECG).
ECG is the “great” sort of examination to make use of for stroke testing, since it gauges the electrical impulses in the heart. When there is a problem in the arteries, the heartbeat will slow or stop entirely. This is the primary sign of whether there is an issue in the blood vessels. This is why it is called the “cardiovascular disease displays.”
There are many different things that go into a testing for a cardiac arrest. These screenings include taking your relaxing heart price, and looking for rises or decreases in both the rhythm and force of your heart. Your resting heart rate is really important, since it provides doctor an excellent idea if you go to risk for a cardiac arrest. There are other points that go into stroke screenings as well, such as things that affect brain function, such as memory and also attention.
When it comes to carotid artery disease screening, the doctors will take a look at your head to see if you have any kind of indications of what is called “tachycardia.” Tachycardia is the irregular rhythm of your heart. The most usual sign of this problem is a pounding heart. Also, if you have a bigger or inflamed heart, it can suggest that you have a more major issue.
An additional thing that they take a look at is the vision. Many people think that if you are doing a typical routine eye examination, after that it suffices. Nonetheless, it is necessary to know that a lot of these screenings will certainly also entail using spectacles or call lenses. If you require to use these to be able to see correctly, after that it is vitally important that you go through a stroke testing for ischemic strokes.
An ultrasound is additionally an additional kind of stroke testing that is done. An ultrasound functions by utilizing acoustic waves to separate any obstructed blood vessels. It essentially trips the clogs up so that the physician can better see what is going on. Blood clots can be extremely unsafe, as well as once they are broken up, they are less likely to be unsafe to your brain. An ultrasound is utilized to not just damage up blood clots, but likewise to damage up huge plaque accumulations in the arteries.

domain: health


11:09am Jul 25, 2016
9:22am Jul 25, 2016
7:12pm Jul 24, 2016
7:10pm Jul 24, 2016
7:06pm Jul 24, 2016
With five games to go, can Hawthorn maintain its two-game advantage at the top of the ladder?
9:30am Jul 25, 2016
Hawthorn is hopeful a transparent approach to Bradley Hill's playing future can take a weight off the wingman's shoulders.
9:15am Jul 25, 2016
Watch Alastair Clarkson's post-match press conference after the Hawks' 70-point win against Richmond on Sunday.
8:00pm Jul 24, 2016
AFL.com.au's five talking points on our big win over Richmond.
5:34pm Jul 24, 2016
Sam Mitchell has celebrated his 300th AFL game with 38 possessions to lead Hawthorn to a 70-point win.
5:20pm Jul 24, 2016
Hawks remain hopeful of keeping Bradley Hill
12:19pm Jul 23, 2016
Hawthorn has finalised their side for Sunday's clash with Richmond
3:48pm Jul 22, 2016
Alex Woodward will make his return for Box Hill this weekend
11:15am Jul 22, 2016
Five players to keep an eye on in our Round 18 clash with the Tigers.
11:06am Jul 22, 2016
Richmond has ruled out vice-captain Brett Deledio from Sunday’s clash.
9:48am Jul 22, 2016
When the Tigers and Hawks meet they're always big clashes
6:29pm Jul 21, 2016
Hawthorn has named their 25-man squad for Sunday's clash with Richmond.
6:09pm Jul 21, 2016
Hawks Family Day is nearly here! Get the family together and come down to Glenferrie Oval this Sunday from 11am – 2pm. We have a fun filled day planned with the guernsey presentation, player appearances, kids’ activities and much more!
4:15pm Feb 25, 2013
The Life Patrons of the Hawks Museum recently held their 8th annual function at Waverley on July 13, celebrating the 60th anniversary of the Hawks’ first team to play a final on the MCG.
5:00pm Jul 21, 2016


text:
By Ignatius Ushie
It was an ambience to behold following a spectacular competition in an enchanting Lakowe Lakes Golf & Country Estate which recently played host to an extraordinary celebration of luxury, golf, and automotive excellence.
Courtesy of GAC Motor Nigeria, a distinguished name in the automotive industry known for its commitment to innovation, quality, and luxury, participants took centre stage at the prestigious event in Lagos.
Between Friday, September 29th and Monday, October 2nd, 2023, the estate was transformed into a world-class destination where opulence met precision, and golfing enthusiasts gathered for an unforgettable experience.
A statement by the organizers revealed that the Golf Championship featured an exhilarating 18-hole championship golf tournament that attracted golf aficionados from far and wide.
Mr. Jubril Arogundade, GM Commercial, CIG Motors, the sole distributor of GAC Motor, expressed his enthusiasm for this partnership, stating, “GAC Motor is proud to be associated with the Lakowe Lakes Golf Classic and Escape to the Green.
“It’s a unique platform that resonates with our brand’s values of excellence and luxury. We are delighted to have been part of such an extraordinary celebration.”
GAC Motor Nigeria showcased its latest fleet of luxury vehicles, elevating the experience for attendees. The brand’s commitment to excellence was evident as guests had the opportunity to explore the cutting-edge technology, unmatched comfort, and timeless design of GAC Motor vehicles.
The Lakowe Lakes Golf Classic and Escape to the Green, powered by GAC Motor Nigeria, was a testament to the synergy between luxury, golf, and automotive excellence. It captivated the hearts and minds of all attendees, leaving an indelible mark in the annals of Nigerian golfing and lifestyle events, the statement added.

domain: news


Organic Ruffle Top Harem Pant - Mauve by Play Up
Brand Play Up
This product is sold out
These trousers are made of jersey stitch organic cotton, Purple Wood colour. The model has elastic waist and hem, a cloth frill round the waist and a decorative wooden button.
Composition: 100.0% Organic Cotton
How to take care
- Normal process 30º
- Do not bleach
- Do not tumble dry
- Iron at low temperature: 110º C
- To take care of the planet, we suggest full and cold loads washings, hang dry and think of ironing only when necessary.
- If you choose this piece, we hope you make the best of it! When it doesn't fit anymore, donate or recycle.


text:
J. Kenji López-Alt
Emily and Matt Clifton
The classic Mexican street food of grilled corn slathered in a creamy chili- and lime-spiked sauce with cheese. Get the Recipe
Peter von Ziegesar
A grand tour of the science of cooking explored through popular American dishes, illustrated in full color.

domain: food


text:
One of the best smelling milk variety bars comes from Mexico. It contains min. 40% dry cocoa solids and has a splendid aroma. It smells angelica sylvestris, ginseng, and a whiskey barrel. A intense taste can be felt even a long time after eating. This variety has a touch of roasted hazelnuts combined with black plums.
Dry cococa solids min. 40%, milk powder, sugar, soya lecithin, cocoa butter, natural vanilla.
Preparation: 60g chocolate and 50ml to be melted in the microwave oven or double-boiler. Stir it well.
Allergens: milk, soya
Weight: 500 g
Nutritional values per 100 g:
Energy value: 2281 kj/ 545 kcal
saturated fatty acids: 23


text:
Motherhood is beautiful. And it is rightfully celebrated around the world.
Mother’s Day is a celebration of the selfless sacrifices that women make to raise a child. Beginning with an extreme physical change to her body, a mother provides a warm, safe place for her child to develop and begin life. Her soft reassuring touch helps her baby grow and learn, often at the expense of sleep and her own needs. Over the years Mom’s wisdom and teachings prepare the child for a successful adulthood.
The celebration of Mother’s Day is in May, when spring is in full swing. I find this timing appropriate, as the flowers that are emerging perfectly embody the beauty of motherhood. Perfume fills the air as flowers burst from tree buds and buried bulbs. Bold colors replace the drab grey of winter, and the landscape comes to life. This beauty and freshness is a direct hit when we compare it to the love we have for Mom.
But there is more.
None of this would be possible without the caring, nurturing hand of the gardener (or the squirrel) the previous year. Without her weeding, mulching, cultivating, planting and watering these flowers are not fueling our smiles. It is this overlooked effort that I appreciate the most. The hard work is done without immediate reward, and often with a fair amount of discomfort. But the imagination and dreams of the gardener make it so.
With that in mind, let’s visit “Tulip in the Rain“, this week’s photo.
Traffic slows on I-64 as the rain pours mercilessly from above. My windshield wipers squeal as they attempt to create a workable view through the glass. The afternoon sky looks like midnight as the storm rolls over the peninsula.
My tires spray the sidewalks as I splash through the city streets. The deluge is harmless as everyone has taken cover inside. Locating a parking stall I ready myself and my rain gear. I love wandering the gardens while they are empty.
Raindrops make sweet music when they land on the garden. Splashing in puddles and bouncing off foliage, the rain brings life and magic. I lunge at the opportunity to experience it in the gardens of Colonial Williamsburg, Virginia.
Entering a third garden, the clouds loosen and the light changes. Warm sunlight shines through the clear sky, reflecting off the glistening rain drops. A red tulip rises to greet it, arching above the surrounding flowers still heavy with rain. Drawn to this flower, I watch the water drops roll to the base and linger before dripping away. More beautiful music!
Thank you for sharing this experience with me. Please share this with your friends and comment below if you have a similarly subtle love in your life. Please visit my website to see “Tulip in the Rain” and many other flower photographs!

domain: artistic


text:
Articles | Open Access
Tridax procumbens has been used in the treatment of several ailments in Kenya, including diabetes mellitus. However, there is limited scientific validation of its efficacy. The aim of this study was to investigate, in vivo, hypoglycemic activity of Tridax procumbens in alloxan induced diabetic mice. Antidiabetic activity was assessed by administering orally and intraperitoneally aqueous plants extract at doses of 50, 100, 200 and 300mg/kg body weight and determining the levels of blood glucose after 0, 1, 2, 3, 4, 6 and 24 hours. The mineral composition of the aqueous plant extract was assayed, using Total Reflection X-ray Fluorescence system (TRXF), while the phytochemicals were profiled using standard procedures. The plant extract demonstrated a dose independent antidiabetic activity in mice model. The studied plant extract contained alkaloids, flavonoids, saponins, tannins, and total phenols at varying concentration. The mineral assay confirmed the presence of detectable levels of K, Ca, Ti, V, Mn, Fe, Ni, Cu, Zn and As. The aqueous extract of the studied plant was effective in lowering blood glucose levels.
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

domain: chemistry


Can I tell you how long I’ve longed for a smartphone from Huawei with an unlockable bootloader?
Every winter when my girlfriend and I visit Hong Kong someone at a phone shop invariably tries to sell me on the latest from this Chinese OEM. And why not? Their “Ascend P” line of sleek, metal and glass smartphones are gorgeous. And phablets? Son, Huawei was doing 6 inch phones long before 6 inch phones were even a thing.
The company’s no slouch when it comes to moving hardware, either. In his final numbers for 2014 Tomi Ahonen ranked Huawei 4th in sales worldwide with 75 million units shipped, ahead of Xiaomi at 61.1 million.
The bad news, as is the case with most Android OEMs, is that the stock ROM on their products is crap. Huawei calls theirs Emotion UI, and most reviews I read of Huawei products—at least from the Western tech press—have nothing good to say about it.
So you can imagine how thrilled I was to read this bit of news on GizmoChina:
Kevin Yang, the Director of China Research at iSuppli, a leading market research firm, confirmed on Weibo earlier today that Google has indeed chosen Huawei as the next Nexus maker.
That article goes on to mention that LG has also been tapped for a new Nexus device. LG’s Nexus might end up being a tablet, or it’s also entirely possible that there will be two Nexus phones this year—a high-end phablet from LG and a more compact and affordable phone from Huawei. Either way, as far as I’m concerned, the more unlockable bootloaders there are out there, the better. To be fair, you can already unlock the bootloaders on some Huawei devices, but I don’t see any of their high-end products in the drop-down list here.
If a Huawei Nexus ends up shipping before the end of 2015 I’ll take it as proof of what I’ve always suspected, that the Nexus 6 is a flop. Maybe they’ll codename this one “apology”. 😛


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Actress and TV presenter who rose to fame in the 1990s. She has appeared as a panelist on the program #Tendencias and hosted the programs Los primeros, Zona franca, and Especial Nochevieja 1992.
She started her career as a model before she was selected to present the program Ponte las pilas in 1991.
She has earned 60,000 followers on Instagram.
Her father is Rafael de Benito. She was married to soccer player Guti from 1999 to 2009 and had two children named Zaira and Aitor.
She played Chica Mafioso in the TV series Telepasión española starring Ana Obregon in 1993.


text:
Invariant organic killer T (iNKT) cells are innate-like T cells that
Invariant organic killer T (iNKT) cells are innate-like T cells that respond to lipid antigens presented by Compact disc1n. iNKT cell function and frequency. We discovered positive organizations between the variety of many types and iNKT cell regularity and their capability to generate IL-4 in the GALT but not really in the bloodstream. General, our outcomes are constant with the speculation that GALT iNKT cells, influenced by certain bacterial species, may play a key role in regulating immune activation in HIV-1 infection. Introduction HIV-1 infection leads to the development of chronic inflammation that persists even in antiretroviral (ART)-treated individuals with undetectable viral loads1,2. This inflammation is associated with non-HIV comorbidities, including cardiovascular disease, neurologic disorders, cancers, and an overall increased mortality. It has become apparent that immune activation is a better predictor of HIV-1 disease progression than either peripheral blood CD4+ T-cell count or viral load3, highlighting the importance of chronic immune activation. However, buy 158013-43-5 distinct pathways of immune activation (innate vs. adaptive) appear to have differential prognostic capacity, depending on the cohorts4. Importantly, while ART significantly diminishes immune activation (particularly if initiated early after infection5), levels do not normalize to those of uninfected individuals. Invariant natural killer T (iNKT) cells are innate-like T cells that respond to lipid antigens presented on CD1d, an MHC class I-like molecule expressed on antigen presenting cells (APCs)6. iNKT cells are characterized by their expression of the semi-invariant T cell receptor chain V24-J18 preferentially paired to a V11 chain. Upon stimulation, iNKT cells are capable of rapid production of a vast array of cytokines and chemokines and are instrumental in orchestrating innate and adaptive immune response7. iNKT cells can recruit and modulate other immune cells, including natural killer (NK) cells, dendritic cells (DC), and conventional CD4+ and CD8+ T cells8. Depending on the type of specific interactions between iNKT cells and DCs, the cytokines secreted by activated iNKT cells may either activate or suppress adaptive immune responses. Mouse studies have shown that the symbiotic microbiota can impact the maturation and function of iNKT cells in the mucosa9,10. A sphingolipid produced by the human commensal genus (Benjamini-Hochberg Q value < 0.15, Supplementary file), a genus that has been shown to be increased in abundance in HIV-infected subject gut microbiomes and associated with elevated mucosal immune activation31. Given that expresses a glycolipid that can activate human buy 158013-43-5 iNKT cells11, we investigated whether the abundance of (OTUs) within the genus was associated with frequencies of iNKT cells in both peripheral blood and GALT within ART-treated HIV-infected subjects, all study subjects combined, and uninfected subjects only (Figure 5B and C, Supplementary file). Fewer OTUs reached P<0.10 for comparisons to peripheral blood as opposed to GALT iNKT frequencies, and no trends were consistent across all subject groupings for comparisons to peripheral blood. However, when comparing OTU abundances to GALT iNKT frequencies, consistent positive associations were found between several OTUs and iNKT frequencies across subject groups. Finally, we looked for associations between OTUs and the capacity of GALT iNKT cells to produce IL-4 (Figure 5D, Supplementary file), though these observations exhibited Benjamini-Hochberg false Rabbit Polyclonal to RAB5C discovery rate Q values > 0.70. These results suggest that loss of the genus in HIV-infected individuals could influence both the frequency and function of iNKT cells in the gut. Figure 5 Change in microbiota in HIV-infected individuals and associations with iNKT frequency and function Discussion Several studies have examined the frequency and function of peripheral blood iNKT cells in HIV-1 infection but limited information is available for the GALT, an important target in HIV-1 pathogenesis. We found that iNKT cells were depleted in the buy 158013-43-5 blood but not in the GALT of HIV-infected subjects and that GALT iNKT cells consisted of an increased proportion of the CD4+ subset. This is in contrast to a previous study that reported that CD4+ iNKT cells are lost in the gut of HIV-1-infected individuals32. The discrepancy between our results and buy 158013-43-5 those of Ibarrondo who have shown that.


text:
The reduced rate would be applicable for both existing and newly disbursed loans
Bangladesh Bank on Monday slashed the interest for agricultural loans to 4%. The new rate will be in place until June 30, next year.
The reduced rate would be applicable for both existing and newly disbursed loans, according to a BB circular issued on the day.
The low interest credit will be disbursed to the crop and grain sector, as per BB circular.
The tenure of the scheme would be effective from April 1 this year to June 30, 2021.
Typically, banks are supposed to disburse farm loans at the highest 9% interest to the farmers. As per the new circular, the central bank would pay 5% of the 9% interest and the farmers would have to bear the rest 4%.
However, the usual interest rate would be applicable on the loans after June 30, 2021.
Bangladesh Bank fixed farm loan target for the current fiscal year at Tk24,124 crore.
In July-February of FY20, banks disbursed Tk15,092.17 crore in loans to the farmers, as per central bank data.
BB also launched another Tk5,000 crore fund for the farmers, setting the applicable interest on 4%.


text:
Mumbai: Veteran actor Anupam Kher, who will next be seen as former Prime Minister Manmohan Singh in upcoming film ‘The Accidental Prime Minister’, on Wednesday revealed the first look of actors Arjun Mathur and Aahana Kumra as Congress President Rahul Gandhi and his sister Priyanka Gandhi respectively.
Anupam took to Twitter to share a photograph from the set in which the he can be seen as Manmohan Singh while Arjun and Aahana donned the looks of Rahul and Priyanka Gandhi.
“Introducing Arjun Mathur as #ShriRahulGandhi and Aahana Kumra as #MsPriyankaGandhi in our movie ‘The Accidental Prime Minister’. @TAPMofficial #OathCeremony #2004 #VijayGutte #SunilBohra,” Anupam captioned the image.
It also features Akshaye Khanna, who will play Baru, and Suzanne Bernert, who will portray former Congress president Sonia Gandhi, among others.
Directed by debutant Vijay Gutte and written by Hansal Mehta, the flick is all set to hit the theatres on December 21, 2018. (ANI)