text: Autosomal recessive Robinow syndrome is caused by mutations in ROR2 and is characterized by short stature, mesomelic limb shortening, brachydactyly, vertebral abnormalities, and a characteristic "fetal face" dysmorphology. We report the clinical and molecular studies on two adults with this condition. Besides typical skeletal and facial features, one patient developed hydronephrosis, nephrocalcinosis, and renal failure. The second patient had characteristic skeletal manifestations including severe spinal involvement and showed endocrinological abnormalities including elevated gonadotropic hormones. The facial phenotype in both patients remained distinctive into adulthood. Analysis of the ROR2 gene revealed a homozygous c.1937_1943delACAAGCT mutation in Patient 1, and compound heterozygosity for c.355C > T (p.R119X). and c.550C > T (p.R184C) in Patient 2. (c) 2005 Wiley-Liss, Inc.


text:
350 E Horsetooth Rd, Fort Collins CO 80525
Business operations may be affected due to COVID-19. Please contact the business directly to verify hours.
Most Recent Comments
As others have stated they did not have enough cars. The reservation was made weeks in advance. They called 10 minutes before the reservation time on a Friday at 3:50, didn’t provide any alternatives and it was too late to find a rental elsewhere. I’d highly advise you look elsewhere if you actually need a rental car.
The employee was fantastic, but clearly they are understaffed and had no one to clean cars while the employee inside worked with a long line of customers.
I reserved a car and prepaid. I called to cancel the next day ( 26 hours) because I booked in the wrong city. I was charged a $100 cancellation fee. So incredibly ridiculous. My reservation was in September.
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Fort Collins, Colorado

domain: travel


A person was in critical condition in a shooting Wednesday afternoon at the Sox-35th Red Line stop, according to police.
At approximately 1:22 p.m. a man was on the CTA train traveling northbound from 55th Street when he exited onto the 35th Street platform, police said.
An unknown person, who was on the same train as the man, approached him, produced a gun and fired one shot, striking him in the neck, officials said.
Police said the man was taken to an area hospital in critical condition. No one was in custody as of Wednesday evening and Area 1 detectives are investigating.
Get Chicago local news, weather forecasts, sports and entertainment stories to your inbox. Sign up for NBC Chicago newsletters.
On Monday, an 18-year-old man was found shot on a Red Line train at a station in the first block of West 69th Street in Englewood.
Earlier this month, three men were wounded in a shooting near the Garfield Red Line station on the South Side.


This post was originally posted at FreeStatePlus on WordPress
Tavis Smiley who personally I like, but generally don’t agree with, but who’s someone who I respect, hosted a panel discussion that C-Span, thank God for C-Span, broadcasted on MLK Day on Monday. If you guessed Tavis Smiley was there, you would be correct, but it had Professor Cornel West, progressive activist Michael Moore, financial adviser Suzie Orman and a young women. Who’s name I can’t remember and I didn’t recognize it.
But I thought what won the panel discussion even though it wasn’t a debate, but hit the nail on the head if you want to use that expression, I would’ve gone farther in what she was saying, but she did a very good job of making points and a case in how to win the War on Poverty. By actually moving people out of poverty, that you generally don’t hear from today’s Progressives. Who generally use their time to bash capitalism, or call for more public assistance.
A lot of this discussion was basically about how we can move away from Capitalism and explaining how President Bush basically screwed the American economy. And that President Obama wasn’t progressive enough to fix it. Because he wasn’t in favor of their big government programs. And calling for more Welfare etc, when it comes to poverty. Progressive Socialists tend to be more about giving people in poverty more Welfare.
More Welfare insurance at taxpayers expense of course. And are more interested in sustaining people in poverty. But this young woman was talking about actually moving people out of poverty. Which is completely different, so they can be self-sufficient and get off of public assistance. And she’s the only person that made this discussion worth watching. the War on Poverty a war that President Johnson declared in 1965 47 years ago. If you were born that year, your Middle Age now.
And today you might not even remember LBJ as President. But the solutions to finally win this war, are pretty simple, but harder to put into practice. First of all you need a good economy that has strong job growth. We are finally starting to see that now. But to help adults who currently live in poverty whether they are working or on Welfare or Unemployment Insurance, is through education and job training. Get them back into school, so they can get themselves the skills they need to get a good job and get off of public assistance. That takes money, but would pay for itself in the long run, because we would be creating new taxpayers.
Long-term what we need to be doing to avoid kids living in poverty as adults. Or end up in the corrections system, is to make sure they stay in school. And get a good education, while their parents are going back to school. And to do this we need to reform our public education system. And that gets to better educators and competition inside the public education system, so low-income parents can send their kids to good schools as well.
Not be forced to send their kids to schools because of where they live. That’s called public school choice and we have to do something about our high dropout rate. Encourage kids to stay in school, not drop out and have kids and end up on public assistance. Or get involved in organized crime and in the corrections system. We proved in the 1990s with the Clinton Administration, with Welfare to Work.
That we can do this, move people out of poverty and into the middle class. By empowering them to get the skills that they need to get a good job and not live on public assistance. To the point that we got our poverty rate down to 13%. I believe a record low for the United States is an approach that we need to get back to.
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Yesterday, a pre-Halloween treat arrived .. Tinker Bell! I had only seen this sculpture via pictures but was just as pleased in person. Margi Wray did another fantastic job on Tinker Bell. You may recall, Margi sculpted the 2005 Disney Bank One Visa credit card exclusive of Tinker Bell from Walt Disney's Wonderful World of Color.
Blithe Spirit is not only the 2008 Fall Event sculpture but also the first release in the Master Artist Series. In the most recent Sketches, there was an article on the origin of this sculpture and how it came to be. David Pacheco's newest design of Tinker Bell presents a popular character in a fresh situation. "The idea for this piece actually came about a while ago," Dave continues. "I had done a random sketch of Tinker Bell for another project and everyone I work with seemed to like it. It was a little more interpretive and something that wasn't taken directly from the film Peter Pan.
"Putting Tink on a leaf helps to show scale and the rich autumn colors really make her stand out. It makes a better statement than a green leaf which would have been too similar to her costume."
Comparing this Tinker Bell to previous releases, she is much larger both in body size and wings. There is a lot of detail and facial expression (she looks great at any angle) and like how Margi sculpted her bangs falling over her forehead. There is a lot of detail in the leaf and like the color palette that was used. Her wings are what strike you as different vs. previous releases, much longer and more of an arch. They appear more as fluttering, relaxed vs. previous releases where she either preening, rocking back and forth laughing or in flight.
Mary being a huge Tinker Bell fan, it was a no-brainer this one would be added to our collection :) I'd like to thank Pam at Cel-Ebration for locating one for me. Waiting too close to the event proved not a good choice in pre-ordering one, as most dealers sold out. Thanks Pam!

domain: design


text:
The game has been released! 6 robots compete on a slick surface with 1/6 the usual friction, similar to rover conditions on the windswept planes of the moon. The 3 robots on your team each drag trailers and try shoot or dunk "Moon Rocks" into the opposing alliance's trailers. Download the Game Animation for an overview and read the Game Manual for the nitty-gritty.
Update (01/11) by Voyagerfan5761: As pointed out by an anonymous commenter, the game is called "Lunacy". Not "Lundacy". Fixed.

domain: entertainment


text:
Full-Time Senior Executive/Executive, Library – Yale NUS College Library
Yale-NUS College Library seeks an energetic, service-oriented individual to perform technical services activities, including acquisitions, inter-library loans and e-Reserves. The Senior Executive/Executive will also assist in the overall operation of the Library and work closely with faculty, students and colleagues, promoting an engaged, proactive style of service supportive of the College’s living and learning environment.
The Senior Executive/Executive performs technical services activities and assists in the daily operations of the Library, including (but not limited to) acquisitions, inter-library loans and e-Reserves, in support of the delivery of library services to the Yale-NUS College community:
- Manage the inter-library loan and document delivery workflow through the ILLiad system
- Manage the Library’s e-Reserve cycle
- Monitor acquisition funds
- Produce statistical and management reports relating to the library collection
- Maintain a policy and procedure manual
- Provide service desk cover. (May involve after-office-hour evening and weekend shifts). Assist library users in locating materials and using equipment. Handle general reference enquiries, including help with databases and other web-based resources
- Supervise student associates
- Contribute to team efforts and the implementation of library-wide initiatives and projects
- Perform other duties, as required
- A Bachelor’s degree
- At least 3 years of relevant experience
- Candidates with library qualifications from an accredited programme may be considered for Assistant Librarian
- Familiarity with an online library system (such as Innovative Interfaces’ Millennium/Sierra)
- Proficient in Microsoft Office applications
- A background in Library IT would be an asset
- Familiarity with the book trade would be an asset
- Be highly service-oriented and enjoy interacting with students, faculty and staff
- Able to work independently with minimum supervision, and as a team member
- Excellent communication and interpersonal skills
- Good organisational and analytical skills
- Keen attention to detail
To apply, please submit your resume and cover letter to firstname.lastname@example.org.
I understand that by sharing my personal data with Yale-NUS College, I authorise its use for the purposes of this application.
If you have any queries, please email email@example.com
Only shortlisted candidates will be notified.
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domain: library


Implicit Generative Modeling for Efficient Exploration
Proceedings of the 37th International Conference on Machine Learning, PMLR 119:7985-7995, 2020.
Efficient exploration remains a challenging problem in reinforcement learning, especially for those tasks where rewards from environments are sparse. In this work, we introduce an exploration approach based on a novel implicit generative modeling algorithm to estimate a Bayesian uncertainty of the agent’s belief of the environment dynamics. Each random draw from our generative model is a neural network that instantiates the dynamic function, hence multiple draws would approximate the posterior, and the variance in the predictions based on this posterior is used as an intrinsic reward for exploration. We design a training algorithm for our generative model based on the amortized Stein Variational Gradient Descent. In experiments, we demonstrate the effectiveness of this exploration algorithm in both pure exploration tasks and a downstream task, comparing with state-of-the-art intrinsic reward-based exploration approaches, including two recent approaches based on an ensemble of dynamic models. In challenging exploration tasks, our implicit generative model consistently outperforms competing approaches regarding data efficiency in exploration.


text:
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|Additional Physical Format:||Online version:
History of Thucydides.
London, Longman, Rees, Orme, Brown and Green, 1829
|All Authors / Contributors:||
Thucydides.; S T Bloomfield
|Notes:||Title vignette (portrait).|
|Description:||3 volumes maps (some folded) 22 cm|
|Responsibility:||newly translated into English, and illustrated with very copious annotations, exegetical, philological, historical and geographical; almost entirely original ... Prefixed, is an entirely new life of Thucydides: with a memoir on the state of Greece, civil and military, at the commencement of the Peloponnesian war. By the Rev. S.T. Bloomfield.|

domain: geography


text:
Flybe isn’t exactly like other airlines. It was founded in 1979 with the idea of connecting the island of Jersey to major airports within the UK and the company has grown throughout 40 years to provide a vital service to many of the UK’s rural or more distant communities and it is these communities who would have been most concerned at the news of the Flybe’s recent financial woes.
There will be significant relief amongst regional and island communities today at the news that the government has provided direct relief to Flybe to allow it to continue to fly.
The government refusal to disclose the precise details of what has been agreed (although we can be certain it includes some forbearance in relation to paying Air Passenger Duty and a commitment to look at it’s overall reduction on domestic flights) has fuelled a not entirely unexpected response from the industry and environmental campaigners. Whilst regional communities served by Flybe might be relieved, the overwhelming feeling this morning at other airlines, and in particular British Airways, was fury.
Even though, any promised reduction in Air Passenger Duty, will have to be applied to all airlines, but even the promise of that was not enough to mollify Willie Walsh.
Willie Walsh, the outgoing chief executive at BA has not minced his words accusing the government of using tax payer funds to subsidise a company whose main shareholders include Virgin Atlantic which is owned by Delta Airlines, one of the most profitable airlines in the world.
His point that it’s unfair that taxpayers have to take on the burden of assisting a privately owned company, (owned by successful solvent entities at that), is hard to argue with, especially if you were affected by Thomas Cook’s recent demise, where the Government choose not to step in, resulting in significant cost and upset in repatriating travellers and supporting the workforce through job losses.
It is undoubtedly a political decision which was made to support specific manifesto commitments by the Conservatives in the run up to the election – but – is it really the right thing to do and does Willie Walsh have a point? Should the tax payers (and arguably the environment) pay to keep Flybe in the sky and is this a move away from the government’s pre-election position of allowing the market to determine private companies’ fate?
The environmental impact of lowering APD across the industry and the expected reduction of funds available to schemes promoting climate change initiatives could be severely impacted. It is hard to take seriously the warm political words committing to averting a “climate emergency” when, on the face of it, they commit to supporting a scheme which makes flying cheaper.
I’ve also seen some discussion that the Government was forced to look at APD because pre-Brexit and before the end of the transition period, State-Aid rules prohibit direct assistance, but this is not entirely true, given that State Aid can be granted to support regional economic development, which is the entire reason for supporting Flybe. In any event, post-Brexit, the proposed State Aid Regulations 2019, which have not yet been enacted, effectively propose to cut and paste the current EU regulations into UK law.
Make no mistake, this was a political decision, and the government have weighed their commitment to letting the market regulate the financial viability of private companies (even if the shareholders are solvent), and the impact on their environmental commitments with balancing a public good in keeping Flybe connecting communities.
It is hard to argue, in my view, when faced with depriving communities of a vital economic and social link, that the Government have not made the right decision, but, it will be interesting in days to come to see how they manage the impact of their choices on their environmental commitment and the fall out from other airlines’ criticism.
Pamela Muir is a Partner in our Corporate team. We are always delighted to talk without obligation about whether we might meet your needs in insolvency and restructuring. Call Pamela on 0131 226 6541 or email firstname.lastname@example.org

domain: politics


text:
Warrnambool is the latest rural centre to open a new recovery-based mental health service, which will free up acute hospital beds and boost local employment opportunities for health workers.
Member for Western Victoria, Gayle Tierney today opened the $4.75 million South West Healthcare Prevention and Recovery Care (PARC) 10-bed facility.
Operations will officially commence in March.
PARC services deliver short-term residential treatment programs for people with a mental illness that focus on early intervention for people who are becoming unwell, and for those in the early stages of recovery from an episode of acute illness.
With 24-hour support from clinicians and around-the-clock support staff – it is strongly focussed on recovery in a home-like environment.
The Warrnambool PARC facility will also boost local employment, creating 12 new full-time equivalent positions for social workers, occupational therapists, allied health workers, and other mental health professionals.
There are now 20 PARC facilities operating across Melbourne and rural Victoria.
The Victorian Budget 2017/18 included a $325.7 million record investment in mental health services to further implement the Labor Government’s 10-year Mental Health Plan to save and improve lives.
Quotes attributable to Member for Western Victoria, Gayle Tierney
“This new mental health support service will boost and improve treatments and ease pressure on other local health services.”
“It’s a new community-based model to support people in Warrnambool with a mental illness on their journey of recovery.”
“PARC units deliver a unique, home-like setting where people with a mental illness can get the support they need to get their lives back on track.”

domain: sociology


text:
Periodontal (gum) disease is a progressive inflammation of the gum tissue. It is most frequently caused by bacterial infection. Left untreated, gum disease can have serious consequences for your oral and overall health. However, one of the biggest challenges for early detection and treatment of gum disease is its silence.
Clearing up misconceptions about oral health can help improve personal oral hygiene efforts for a beautiful and healthier smile. If you keep up with your oral hygiene regimen, dental visits are significantly easier and dental care is more manageable.
Misconception #1 – My teeth are fine if I have no pain
Tooth decay (cavities) usually doesn’t cause pain until they become very severe.
Alveolar osteitis, more commonly known as dry socket, is a temporary complication that can occur following a tooth extraction. Fortunately, it is rare, preventable, and short-lived. Here are some tips to help avoid dry socket after oral surgery and ensure a quick and comfortable recovery.
Many people want a smile they can be proud of and one way to achieve a dazzling smile is to have pearly white teeth. However, in order to maintain a bright smile, the Aberdeen dentist says you should be mindful of the types of things you consume.
Are you a diligent brusher who grabs the toothbrush as soon as you finish each snack or meal? While there are significant benefits to regular brushing, hurrying your hygiene might be doing more harm than good. The key lies in understanding the effects different types of food and drinks have on your teeth.
Maintaining your gum health is vital to your overall health. When you visit our office for an examination, our trained hygienists perform a periodontal exam. In fact, during your examination, our team is quietly assessing your oral health by performing a number of checks.
During a comprehensive dental examination, our team will look for signs of oral cancer. Early detection is key with oral cancer. If caught early, most forms of oral cancer are treatable. Our dental team is trained and educated to identify oral cancer.
is susceptible to the disease,
We all know the importance of making a great
first impression. Whether you’re going into a job interview or about to go on
your first date with someone new, you want to have the confidence that comes
with a great smile. After years of wear and tear however,
iTeeth grinding, known as bruxism, is a habit many get into without even realizing it. Grinding your teeth can be damaging for several reasons. If you or your child have been struggling with teeth grinding, make an appointment to see us. We will assess the damage to the teeth,
Calcium is an important mineral for building strong, healthy teeth, but not everyone can tolerate the lactose found in dairy. Lactose is a sugar found in milk and other dairy products. About 65% of people have reduced ability to process lactose past infancy.
If you have
difficulty with lactose but want to ensure you are getting the calcium you

domain: medical


Real Estate GTA Buying Tips and Advice Neighborhoods Guide
Vaughan is located in the Southern Ontario region and is the second most populous city in Canada. Over the years, the population has grown by 10.9% since 2011, from 288,301 to 329,100 in 2016. Specifically, it is located in the North York region of Toronto, and covers an area of around 273sq kilometers. The city's business culture has witnessed a manifold growth rate and has successfully achieved exponential development in the past five years.
Vaughan's successful business model has resulted in more employment for more than 200,000 people by 10,000 different existing companies. Having the highest percentage of employment-to-home ratio in the entire GTA, Vaughan is set to sustain economic growth for the next 20 years. Such a vibrant and grand status of a city is rare, which is why Vaughan is a popular choice among residents. In this article, we have listed the best neighborhoods in Vaughan and why you should consider buying a home there.
Kleinburg, lying towards the northern end of the city, is one of the best neighborhoods of Vaughan. This community offers its residents and visitors a safe, quiet and exotic lifestyle experience, far away from any sort of chaos, unrest or violence. Kleinburg is preferred by many as it is a posh area, home to several wealthy and prominent groups of people, which reflects the overall grandeur of the entire neighborhood. What's even more intriguing about it is that it incorporates both 19th century traditional houses as well as recently developed estates.
Besides having a luxurious outlook, Kleinburg also comprises extensive tourist attractions. In addition to various shops and restaurants, there is the McMichael Art Gallery, which houses an intricate collection of Canadian art. The area also hosts events such as the annual Christmas tree lighting, Canada Day, and the annual binding rope festival. In terms of outdoor activities, Kleinburg has plenty of places to bike, hike, canoe, and even enjoy cross-country skiing. For those who prefer a more conservative outdoor excursion, the Copper Creek Golf Club is an ideal choice.
To the west of Vaughan lies Sonoma Heights, a neighborhood filled with community-conscious young families, which makes it rank among the best neighborhoods in Vaughan. If you are someone who loves living in a community setting in Vaughan, Ontario and connecting with your neighbors, Sonoma Heights is your ideal choice. It is primarily a family community, with an average of two young children per household. Only around 3% of the residents in this area are tenants. In order to become a homeowner in this community, you must be prepared to spend somewhere between $ 780,000 to $ 1.3 million. Major proportion of the houses are meant for single-families, and some are semi-detached or semi-detached.
There is a lot to love about Woodbridge, especially the intriguing combination of houses; from charming townhomes to large and spacious homes, there is something for every home seeker. All property buyers are likely to find a variety of high-end options in West and East Woodbridge, prices ranging from $791,024 to $1,015,481 on average. About 34% of the permanent residents of this neighborhood are hitched and settled with either one or two children.
In terms of family-concerned amenities, Woodbridge ranks well as it has high-value local schools like St. Gregory the Great and Glenn Gould Public School. In terms of closeness to nature, it scores well again due to its serene natural beauty. The entire region of Area Flock to Boyd Reserve is a natural wonder, which makes Woodbridge rank among the best neighborhoods in Vaughan. Linguistically, 47% of the population speak Italian and 38% speak English.
Maple is certainly one of the best neighborhoods of Vaughan as it is a combination of everything that a resident desires for. Over the years, Maple has been a popular choice of residence due to its new and affordable range of housing facilities. The average price of a home here is $902,339, which is lower than other communities in Vaughan. Talking about the community, 43% of the population in Maple are couples having children.
Major proportion of residents are English speakers (75%), and the other major linguistic group is Italian speakers (13%). On an overall basis, Maple is an ideal neighborhood to move into with your family, especially if you have children. It has some top-notch schools like Michael Cranny Public School, which can offer quality education to your child.
5. Weston Downs
Weston Downs is often considered one of the best neighborhoods in Vaughan for the ones who are looking for an upgrade in their housing community. It lies to the west of Highway 400 and stands between 73 and Langstaff Roads. The greater outlook is that Weston Downs is a neighborhood meaning to entrepreneurs and corporate professionals, but in reality, it is also a family-friendly community. Due to high demand and other lucrative amenities, people flock here in large numbers, which has soared the value of its real estate market. Major proportion of the community is filled with well maintained complexes and single family homes.
4800 Yonge St, Toronto COMING SOON
2305 Sheppard Avenue East, Toronto COMING SOON
Simcoe Street North & Winchester Road East, Oshawa, ON, Canada Selling
199 Main Street North, Brampton, ON Selling
224 Kerr Street, Oakville, ON Registration
10 Dawes Road, Toronto, ON Selling
Saw Whet Boulevard, Oakville, ON Selling
1388 Dundas Street West, Oakville, ON Selling
121 George Street, Toronto, ON Selling
30 Francis Street South, Kitchener, ON Selling
3079 Pharmacy Avenue, Toronto, ON Selling
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Kingston Road & Liverpool Road, Pickering, ON Selling
391 Yonge Street, Toronto, ON Selling


The coronavirus positivity rate dipped to 10.55 per cent in the national capital on Tuesday from 11.79 per cent on Monday though the count of positive cases of Covid-19 rose to 6,028 from 5,760 yesterday, according to the daily health bulletin issued by the Delhi government. The number of tests conducted was 57,132.
The virus caused 31 deaths during the past 24 hours against 30 such fatalities reported the day before. The cumulative figure for such casualties stood at 25,681.
The number of active cases of the coronavirus fell to 42,010 from 45,140 yesterday.
There were a total of 15,420 hospital beds available for Covid-19 patients, but 13,116 beds remained unoccupied.
The city had 817 coronavirus patients being treated in ICUs and 760 were put on oxygen support. There were 162 critical patients who were put on the ventilator.
The health bulletin showed that 85,418 persons were given vaccines during the past 24 hours with 36,931 getting their first vaccine dose.
The cumulative count of the people having got their first vaccine dose was 1,68,73,739 whereas there were 1,21,76,369 persons who had got their both vaccine doses so far.


Broadcomintroduced the first quad-core HSPA+ processor with 5G Wi-Fi, near-field communication, GPS, and indoor positioning. The company said the BCM23550 processor is designed for high performance entry-level phones, and is built for the Android 4.2 Jelly Bean mobile operating system.
The company said the new processor is a "turnkey solution" that will allow smartphone makers to quicken production of full-feature 3G smartphones, because the chip works with current smartphone designs that have similar-sized Broadcom chips.
In a press release, Broadcom's Vice President of Product Marketing and Mobile Platform Solutions, Rafael Sotomayor, said, "By combining the performance benefits of a quad-core solution with high-end features like 5G WiFi, globally certified NFC technology, and advanced indoor positioning technology, the platform offers device manufacturers a flexible and cost-effective path to address the affordable smartphone segment."
Some of the chips' main features include:
Quad 1.2GHz A7 CPU
21 Mbps (megabits per second) of HSPA+ downstream connectivity, with 5.8 Mbps upstream
Dual HD display support
VideoCore IV high-performance graphics
Full 1080 HD camcorder and playback
HD voice support
Near-field communication support
5G Wi-Fi technology
Broadcom expects production of the new chip begin in Q3 2013, and is sampling the chip right now.
The article Broadcom Introduces Powerful Chip for Low-End Androids originally appeared on Fool.com.
Fool contributor Chris Neiger has no position in any stocks mentioned. The Motley Fool has no position in any of the stocks mentioned. Try any of our Foolish newsletter services free for 30 days. We Fools may not all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors. The Motley Fool has a disclosure policy.
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text:
|Application ||WB, E|
|Calculated MW||59633 Da|
|Antigen Region||368-400 aa|
|Other Names||Deformed epidermal autoregulatory factor 1 homolog, Nuclear DEAF-1-related transcriptional regulator, NUDR, Deaf1|
|Target/Specificity||This Deaf1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 368-400 amino acids from the C-terminal region of human Deaf1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Deaf1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor that binds to sequence with multiple copies of 5'-TTC[CG]G-3' present in its own promoter and that of the HNRPA2B1 gene. Down-regulates transcription of these genes. Binds to the retinoic acid response element (RARE) 5'- AGGGTTCACCGAAAGTTCA-3'. Activates the proenkephalin gene independently of promoter binding, probably through protein- protein interaction (By similarity). Regulates epithelial cell proliferation and side-branching in the mammary gland. Required for neural tube closure and skeletal patterning. Controls the expression of peripheral tissue antigens in pancreatic lymph nodes. Isoform 1 displays greater transcriptional activity than isoform 2. Isoform 2 may inhibit transcriptional activity of isoform 1 by interacting with it and retaining it in the cytoplasm. Transcriptional activator of EIF4G3 (By similarity). May also involved in behavior (PubMed:24726472).|
|Cellular Location||Isoform 1: Nucleus. Cytoplasm.|
|Tissue Location||Ubiquitously expressed during embryogenesis, with higher expression in regions of the central nervous system, dorsal root ganglia, submandibular gland, epidermis and breast. In 12-week-old NOD mice, expression of isoform 2 is sevenfold higher in lymph node stromal elements than in T-cells and tenfold higher than in B-cells.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Drosophila Deformed epidermal autoregulatory factor 1 (DEAF-1) is a DNA-binding protein that interacts with regulatory sequences first described in the Deformed epidermal autoregulatory element.
Czesak,M.,J. Neurosci. 26 (6), 1864-1871 (2006)
Hahm,K., Mol. Cell. Biol. 24 (5), 2074-2082 (2004)
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domain: health


text:
MarineMax, Inc., the recreational boat and yacht retailer, announced that it has entered into a definitive agreement to acquire Island Global Yachting LLC (IGY Marinas), which operates a collection of marina assets and a yacht management platform in key yachting destinations.
The time-honored road trip is making a comeback. More Americans are traveling by car to visit family and for vacations. A survey conducted in May 2020 by the GasBuddy app revealed that almost one in three Americans intended to take a summer road vacation. Experiencing new things is made possible by road trips. You can do a few things to improve your holiday and make it memorable for the right reasons, whether you are traveling locally for day trips or hitting the road for a lengthy bucket-list journey across the country.
With climate change and overtourism affecting our daily lives, sustainability and mindfulness have entered the travel discussion. Acting in ways to better our communities has shifted from environmental concern to activism in specific spaces, including the tourism industry. So, precisely what is sustainable travel? In its basic form, sustainable tourism is travel that has a positive long-term and short-term impact on a local community, environment, and economy.
Pets have long since provided incomparable companionship and it is getting harder to go away on long trips without them. Referred to as man’s best friends, pets have become part of the family and become hard to disregard in most societies. Therefore, when you next plan your family vacation, you might want to consider your cat or dog as you plan your trip.
There is no doubt that the pandemic has had a tremendous impact on how we live and work today. The past two and half years have seen an overhaul of a system we once imagined untouchable. Terms like hybrid work and remote work sprung forth in a bid to initially fight off the COVID-19 virus but are now household as firms struggle to keep their employees happy.
As the world adjusts to the return of normality and people are planning more holidays, leading caravan, campervan and motorhome rental platform, Camplify, has conducted a study, which found that 85% expect to stay within the country for their next holiday.
The effects of the pandemic still reverberate as businesses try to steady themselves after the harrowing two and half years. It is safe to say that the travel restrictions meant to curtail the spread of the pandemic had a severe effect on the travel and tourism industry worldwide.
I was much inspired to take this valiant step for the first time in 2019 after reading Cheryl Strayed’s Wild, a travel memoir detailing the author’s experience on solo trips. And whereas to many, it sounds erratic to move across the world all by yourself, solo travel is one of the most authentic spiritual remunerations you will ever experience. However, decisive precaution and planning have to be exercised before setting off for a wild trip to a foreign country.
Kings Park in Perth leads a new study by Remitly, a digital financial services provider for immigrants and their families, who has revealed the top five viewpoints in all of Australia, and three locations in each State and Territory preferred by interstate and international visitors. The best place to navigate the sheer wonder of Australia’s vast openness and natural beauty are from those locations that offer the best views. Remitly analysed over 1.4 million TripAdvisor reviews to find which attractions have left visitors talking about its view most regularly. The results were then ranked to name the greatest viewpoints, and within each part of Australia.
Over the past decade, blockchain technology has gained traction, with many taking a sudden interest. But is it time to concede that it is a viable technology? Given the many black-market paradoxes associated with this technology, I get the reluctance to fully onboard the Crypto.


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Not many people in metro Detroit's Mexican immigrant population arrived here from the central Mexican state of Oaxaca. That's a slight bummer because while we're not short on good Mexican food here, that region's cookbooks hold what many argue are some of Mexico's best recipes.
That's where you'll find tlayudas, enfrijoladas, tamales Oaxaqueños, empanadas (Oaxacan-style), and, of course, the mole — Oaxaca is known as the "Land of Seven Moles," and the complex sauce is the region's culinary lifeblood.
Metro Detroit, conversely, might as well be known as the "Land of Little Mole," and none of Oaxaca's dishes are well represented here. That's why a restaurant called "Oaxaca" in Troy caught our attention. Oaxacan-native siblings Juan, Maria, and Carmen Velasco opened the restaurant in September 2015, and the compact menu holds several of the region's dishes, including tlayudas, molotes, and mole.
Oaxaca lists those three items under a short section called "Oaxacan Dishes," while the menu's remainder is devoted to more familiar offerings — tacos, burritos, and tortas. While burritos aren't common in Oaxaca, there's no issue with the addition of the familiar (and gringo-ification, if you consider the dollops of sour cream) because the nearly perfect meats render the vessel less important.
But more on that in a moment, because the Oaxacan part of the menu is what we came for. Start with the molotes which are essentially deep-fried, crunchy empanadas rolled with masa stuffed with salty chorizo and potatoes. The package is topped with refried black beans and soft, mild queso fresco.
It's hard not to think of a pizza when a tlayuda is set on your table, but that's only for the appearance. The roughly 14-inch round masa cracker holds a tangle of crunchy light green cabbage shreds, ropes of stringy, white quesillo, and refried black beans, along with your choice of meat — we opted for chorizo.
Oaxaca's only mole is listed as "chicken mole," but it's a mole negro — a deep, dark, and complex sauce that's the sum of diverse and complementary ingredients like chile guajillo, plantain, chocolate, and more roasted chile peppers. Oaxaca's version is made from a paste imported from Oaxaca, as most of the ingredients can't be found in Michigan. Still, it's a rich sauce and used to drown three large hunks of chicken that arrive with rice and black beans.
But on recent visits the other diners seemed more interested in the burrito, and a friend who lives nearby told me "word is out on this place" because of the burritos. Of course, a burrito only goes as far as its meats will take it, and at Oaxaca the meats stand out.
The al pastor, for example, is sweet and savory with a slight char, though the latter is from the chef's griddle-work as opposed to the trompo. But with flavor like this, a trompo-less kitchen can be forgiven. Oaxaca's asada is among Detroit's most flavorful, and is marinated in a lime, orange juice, and seasoning combo that's common in Oaxaca. The piquant chicken tinga is another hit, as is the salty chorizo crumbles that are light and fluffy or charred, as opposed to the usual greasy balls. (We sure would love to see some chapulines, Oaxaca.)
So pick your vessel for the meats. Oaxaca's burritos are reminiscent of those in San Francisco's Mission District — as big as your head. The tacos are folded into homemade corn tortillas, and the tortas arrive on big, circular, crusty teleras buns.
There's no booze at Oaxaca, but it does have three varieties of aguas frescas and a wide selection of pops. The spot fills up fast midday, as the tiny dining room holds three tables and a counter at which to stand and eat. Perhaps the biggest drawback to Oaxaca is its location in a strip mall far north of town, but that's a short journey to make for a plate of Oaxacan fare.


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The Old Plaza Firehouse is the oldest fire station in the city of Los Angeles, built in 1884. It is located near Olvera Street in the Los Angeles Plaza Historic District. It was placed as a California Historical Landmark No. 730 on April 8, 1960.To visit Old Plaza Firehouse on your trip to Los Angeles, use our Los Angeles attractions planner.
Designed by local architect William A. Boring [the City paid him $160.75 for his drawings], and built in 1884, it operated as a firehouse until 1897. The building was thereafter used as a saloon, cigar store, poolroom, "seedy hotel", Chinese market, "flop house", and drugstore. The building was restored in the 1950s and opened as a firefighting museum in 1960.
The Plaza Firehouse Museum is open to the public Tuesdays through Sundays from 10 a.m. to 3 p.m. The museum features helmets, photos, and firefighting equipment of the late 19th and early 20th centuries.
Old Plaza Firehouse Reviews
Really, it's one large fire engine and one rather interesting very small and early pumper. But the history you come away with is largely what you take in. If you are in the square at Olvera drop... more »
The museum is quite small, but it's free and interesting so definitely worth a visit if you're nearby. more »
Walked into this place while I was waiting on someone. I had no idea of its history at the time. It's preserved pretty well.
Great historical fire house that had lots of cool interesting facts.
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domain: history


text:
Konnichi wa, your Excellency Demon Kogure... I've been a Shinja from the Philippines for only 6 months!!! Thanks to Dragonball Kai (you performed the song "Tada Kogoeru Elegy"), my fave anime, who became the bridge of knowing you and SEIKIMA-II. I had learned to listen all of your songs and I really love it. Even though, you haven't met me, through my fellow Shinjas, I would like to thank you for your kind and humorous words especially when Don Howard tried to tell you about me, you asked him if I'm his girlfriend so, I was surprised and even your awesome laughs as I watched your clips, you really make me smile everyday... you're a DEMON in my heart!
From your Filipino Shinja :)))))))

domain: hobby


Electro Mechanical Maintenance Tech III
C & W Services
San Marcos , TX 78666
Posted 8 months ago
This Job is not relevant Tell us why
C&W Services is the industry leader in Integrated Maintenance Solutions providing service to more than 600 companies worldwide. We're also a sister company of Cushman & Wakefield .
We are partnering with Amazon and looking for an Electro-Mechanical Maintenance Technician to work with automated packaging and distribution equipment at our San Marcos, TX location.
- Weekly Pay
- Comprehensive Benefits that start on your first day
- Advancement Opportunities
- Training to work in a C utting E dge F acility
- A Safety First Culture
- Utilizes working knowledge and experience in the areas of VFD' s, Motors, Wiring configurations, PLC' s, Computers, Electrical Schematics, Control Circuits , Electrical Distribution Systems and Preventive / Predictive maintenance .
- Mechanical expertise, to include, but not limited to, Precision Alignment, Rigging, Tensioning fasteners & belts, Lubrication, Lacing & tracking of belt systems, Mechanical drawings, and Preventive/Predictive maintenance.
- Assist in formulating standards / work procedures while performing those duties and provide work order feedback on discrepancies noted in service delivery.
- Assigned tasks list to include, but not limited to repairs and preventive maintenance on conveying systems, power transmissions, and other power driven rotating equipment. Repairs and preventive maintenance to be performed in conformance with established standards.
- Education : Possess a high school degree or an approved GED. Associate degree in Industrial Maintenance or equivalent,is preferred but not required.
- Five years experience in industrial electrical / mechanical maintenance
- Operate and have knowledge of simple and complex heavy industrial equipment such as forklifts, scissors lifts, and boom lifts.
- Proper use of hand / power tools, shop math, pneumatics, power transmissions, parts nomenclature, measurements and fasteners.
- Available to work 3rd Shift on a '4 nights on, 3 nights off' schedule
Come work with our team! We are a hard-working, committed group of people who believe in delivering quality service to our client.
We love coming to work each day to help clients keep their facilities running in top condition with no downtime . Does this sound like something youd like to be part of? Join us!
ABOUT C&W SERVICES
A leader in facilities services with 65 years of experience. C&W Services is one of the largest facility services companies in the USA & Canada with a 65-year history of helping clients drive down operating expenses, increase facility efficiency and up-time, enable strategic business decisions and create positive experiences for the people who work, shop, learn, live and play in the facilities we maintain. Were building the best team in the industry our people are the heart and vitality of C&W Services. In joining C&W Services, youre joining a firm with a rich history, blue-chip client list, and the backing of sister company Cushman & Wakefield, one of the worlds largest property advisory firms and the reason for our success is simple: talented people. Visit our website at https://cwservices.com.
Learn why C&W Services is an ideal place for veterans to continue their careers: https://cwservices.com/veterans/
We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.


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I was set in a big room with one bunkbed, a lamp, and some clothes in the back. Once I walked into the room they shut it and locked it, I looked around it looked like no one was here but there was...."you must be Sabrina" the voice said, I was startled, I looked around again and saw a tall figure standing in the far right corner.
"Y-yeah how did you know?" I asked moving closer to the black figure.
"I just do, I'm Kyle by the way" he stepped out of the dark and I saw the most gorgeous guy I've ever seen. He had brown hair, and blue eyes, and a lip piercing.
"Why are you here, what'd he make you do?" I questioned, by the look on his face he did something terrible.
"No I didn't do anything,"
"It's okay Kyle, I did something that I regret too" I grabbed his hand and looked at him, he took a deep breath and said,
"He made me um he made me beat someone he told me that if I didn't do it that he would kill me and my family so I did it"
"I used to date him, he told me he was 17 but he lied he's 30" I said, he looked at me for a second before nodding.
"LIGHTS OUT" one of the guards shouted from behind the door. I looked at him before motioning towards the bunk bed, I didn't change into the clothes they provided us, I was to scared too, I laid down, I couldn't go to sleep knowing I was kidnapped by the guy I used to love...

domain: literature


Fayette Tool has the expertise, technology, and people to provide turn-key production stamping services. Our experience in precision aluminum stamping and spray flux application makes us uniquely capable of supporting the needs of climate control applications.
Fayette Tool specializes in aluminum stamping components for climate control applications in the automotive heat exchange industry. Manufactured products include radiator, condenser, heater core, evaporator, charge air cooler, water cooled charge air cooler, and battery cooling stampings. Aqueous cleaning, thermal degreasing, deburring, and spray flux applications are also offered to improve the quality of customer manufacturing processes.
First and foremost it is the tooling that governs the quality and repeatability of the stampings. With an original foundation of designing and tool making, we have the gained experience and full understanding of tooling design and how to best maintain the tooling. We have onsite immediate, preventative, and predictive maintenance capabilities, with the support from our own machine shop.
Fayette Tool has certifications for both IATF 16949: 2016 and ISO 9001: 2015. Our internal laboratory is capable to perform the required inspection, testing, and calibration in house. All testing and calibration is performed with equipment traceable to NIST. Our external laboratory is accredited to ISO 17025.
On average, Fayette Tool Project Engineers have 24 years of automotive experience. From prototype through production, they provide outstanding support and professional customer service for product development, tool design, and project management. Technical and engineering services are supported by the latest CAD software including AutoCad and SolidWorks.


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By Kim Golding,Julia McConville,Steve Killick,Dan Hughes
Psychologist Kim S. Golding indicates how one can use tales to construct connections with kids elderly 4–16 and help their restoration from trauma and pressure. She illustrates the ideas with 21 tales tailored from her personal medical paintings with young children and households, and explains how one can extend or adapt them to cause them to extra appropriate for a selected baby. recommendation and tales are prepared into sections facing universal mental concerns, together with on reflection and relocating on, loss of belief and wish for recognition. Golding additionally provides precious information for making plans tales and lifestyles tale paintings, and for storymaking with little ones. She additionally describes how tales can be utilized therapeutically with mom and dad of traumatized youngsters and as a device for self-reflection by means of counsellors.
Imaginative and sensible, this booklet might be tremendously important for counsellors, psychologists, therapists and social staff operating with traumatized childrens, and also will be valuable for fogeys and carers eager about healing parenting.
Read Online or Download Using Stories to Build Bridges with Traumatized Children: Creative Ideas for Therapy, Life Story Work, Direct Work and Parenting PDF
Best adolescent psychology books
How do I deal with an competitive baby absolutely whilst i've got twenty different childrens who desire my recognition? How am i able to enhance an excellent dating with a baby I appear to dislike? How do I preserve a favorable operating dating with the oldsters of a disturbed and traumatic baby? Written in a jargon-free, readable type, with many actual lifestyles examples, this ebook is a must have source for playworkers trying to increase their abilities as an entire.
Depressive problems are one of the most typical varieties of psychopathology within the United States. Adolescent-onset depressive issues signify really insidious stipulations as a result of their powerful organization with persistent and recurrent emotional difficulties in maturity. This instruction manual bargains authoritative studies of analysis at the nature, motives, and coverings for melancholy in youngsters.
Little ones will adventure common progress and alter all through their lives. Play, via its very nature, constantly leads to issues falling aside, usually actually, and youngsters in most cases locate delight during this strategy of cave in and renewal. This ebook harnesses the facility of the reorganizing strategy to elicit confident and profound swap in kids facing social, neurological, developmental, health and relatives concerns.
Young ones and children with reasonable and serious disabilities frequently have conversation demanding situations that cause them to use challenge habit to express their wants. this can be the main complete modern quantity on sensible conversation education (FCT)--the individualized tutorial procedure that teaches a baby socially applicable communicative possible choices to aggression, tantrums, self-injury, and different unconventional behaviors.
- Suicidal Behavior in Children and Adolescents (Current Perspectives in Psychology)
- Beyond Reason and Tolerance: The Purpose and Practice of Higher Education
- Cognitive Therapy for Depressed Adolescents (Mental Health and Psychopathology)
- Early Childhood Mathematics Skill Development in the Home Environment
- Early Recollections: Interpretative Method and Application
- International Perspectives on Child and Adolescent Mental Health: Selected Proceedings of the 2nd International Conference on Child and Adolescent Mental Health, Kuala Lumpur, June 2000
Additional info for Using Stories to Build Bridges with Traumatized Children: Creative Ideas for Therapy, Life Story Work, Direct Work and Parenting
Using Stories to Build Bridges with Traumatized Children: Creative Ideas for Therapy, Life Story Work, Direct Work and Parenting by Kim Golding,Julia McConville,Steve Killick,Dan Hughes

domain: psychology


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Rebuttal to Tony Abbott’s “Why I’ll say no to same-sex marriage”
Tony Abbott wrote an article in the Australian on why he’ll vote no for same-sex marriage. Here is my response.
Same-sex marriage is a tough issue. It divides families; it splits political parties; often enough, it tears at individuals, too.
Agreed. Needlessly so.
It was definitely rending the Liberal Party in mid-2015 between those sure that the institution at the heart of our society must not be redefined to suit a politically correct minority, and those worried that our stance was unfair and standing in the way of history. We needed to find a way forward that would not just decide the issue but would reconcile the public with the result.
This is a conflation between religion and legislature. The Marriage Act doesn’t seek to define marriage in the eyes of God. It defines marriage in the eyes of the law and the proposed changes simply afford same-sex couples the same rights as straight couples. The use of the phrase “political correctness” is an emotional appeal to those who oppose it despite the issue of marriage equality having nothing to do with political correctness.
The conclusion I came to (and that Malcolm Turnbull has respected) was that a plebiscite was most likely to reassure people that their views had been taken seriously and that the outcome was fair. It would ensure that the issue had been carefully weighed and the best possible decision made.
The decision is a binary one, it is not a discussion or a series of options.
The mental and emotional toll on LGBTI community is clear. Quantifiably, independent modelling by PwC estimates the economic costs of a plebiscite at half a billion dollars. Marriage equality is about fairness by definition, straight sex couples already have the right to marriage; marriage equality is seeking to redress that. In terms of the pathway to marriage equality, wouldn’t it be “fair” to use the same process used by the Howard Government in 2004 to exclude same-sex couples from the definition of marriage?
It was least likely to produce ongoing acrimony, for who could back their individual judgment against a vote of the whole people? After all, it’s marriage that creates families, families that make up communities, and communities that build our nation.
As evidenced by the hurtful and hateful commentary already, acrimony has been magnified rather than mitigated. Agreed, marriage is a societal glue, all the more reason to open it up to all Australians without prejudice.
On such an issue, where change would never have been imaginable to our constitutional founders, it was right and proper to refer it to the people rather than just leave it to the parliament because everyone would have some ownership of the final result.
Many laws are enacted by parliament that would never have been imaginable to our constitutional founders. That is the role of parliament.
Now that the vote looks like going ahead, the challenge is to have a debate that takes seriously the ramifications of changing something that is so central to the way we live. It’s a pity that the advocates of change haven’t finalised what they think are fair protections for freedom of religion and freedom of speech in an era of same-sex marriage because it’s hard to be sure about something without knowing exactly what it may entail.
These are valid and well understood concerns the detail of which will be debated and addressed in parliament irrespective of any plebiscite.
Another disappointment is the tone of so much of the same-sex marriage advocacy. If polls are right, most support change so the plebiscite should be a way of reassuring people that it won’t strain the social fabric. Instead, the activists have insisted that the general public can’t be trusted to have a sensible debate and make a considered decision.
The concern isn’t that the general public “can’t be trusted”. It is the responsibility of parliament to redress the inequality without subjecting the LGBTI community the humiliation of having the rest of the population cast an opinion on whether they are to be afforded the same rights as the rest of society.
Last week, one very senior Labor senator attacked the Prime Minister for allegedly exposing her children to “hatred” because of their family circumstances.
It is not homophobic to maintain that, ideally, children should have both a mother and a father. Yet I fear much moral bullying in the weeks to come — invariably from those demanding change.
The opinion that “ideally, children should have both a mother and a father” is not what Senator Wong was referring to. She referred to the hateful and explicitly homophobic comments by organisations such as the Australian Christian Lobby. It is disingenuous to promote a plebiscite only to characterise the defense of victims of abuse as “moral bullying”.
For me, voting no will not be a criticism of gay friends and family members; it won’t be an assertion that there’s only one right way to live your life or to express your love. Rather, it will be an affirmation that the things that matter should not lightly be changed and that marriage is different from other relationships.
Same-sex couples will exist in and out of wedlock, as do all couples. I would argue preventing same sex couples from marrying weakens marriage as an institution, love exists regardless of marriage. Again, we are not debating the religious definition of marriage.
Ask yourself what is the most decent and respectful thing to do: is it to endorse this change that the gay lobby is stridently insisting on or is it to question whether a few years’ agitation should unmake a concept of marriage that has stood for many centuries and has always been regarded as the rock on which society is built?
The decent and respectful thing to do is to respect the choice of all members of society to participate in the institution you hold dear; an inclusive approach can only strengthen the rock.
Ask yourself what’s more likely to maintain respect for marriage and to reinforce the notions of constancy and selflessness that sustain all lasting relationships: an ongoing recognition that marriage is a union of one man with one woman, preferably for life and usually dedicated to children; or changing marriage so that it can mean any two people who love each other?
There are straight couples who marry and divorce or do not have children. It is not up to external parties to impose familial requirements on others.
Thankfully, censoriousness towards gay people has long gone. I admire the courage of those who battled discrimination (and worse) to establish the equal rights and dignity of all people regardless of race, gender, religion or sexuality. I am grateful for the decency of gay friends (such as Christopher Pearson) who have deepened my understanding of the human condition.
Agreed. It is important that it be reflected not only in our words but in our actions.
But I am baffled by the claim that gay relationships are somehow diminished without the badge of marriage. Unmarried people are not lesser humans than married ones. Couples with children are not greater than those without. Same-sex partnerships are not lesser than opposite-sex ones. They’re just different.
Indeed, love is love. One does not have the right to dictate the manner in which a couple wishes to consummate their relationship.
We Australians are an easygoing and open-hearted people. Our tendency is to take people as we find them and give them the benefit of the doubt. We hate injustice and yearn to help everyone who’s doing it tough. But that doesn’t make it right to acquiesce in every request or to accommodate every demand.
We are not acquiescing to every request or demand, we are simply affording a group of people the same rights as another group of people.
Of course, there has always been an honour in marriage beyond that of other relationships. By all means, let’s find means to solemnise same-sex commitments and impose on them the demanding mutual obligations that spouses undertake; but I doubt that’s what most activists have in mind. To them, I suspect, it’s about status rather than responsibilities.
Marriage equality advocates are not asking for a special category of marriage with diminished responsibilities; just one with the same set of entitlements, protections and responsibilities as straight couples.
The best claim for same-sex marriage is that it will reinforce stable and committed relationships.
In New Zealand, though, where civil unions have been allowed for more than a decade and same-sex marriage since 2013, the marriage rate has been in the same slow, steady decline as elsewhere in the West, so it’s hard to avoid the conclusion that broadening marriage weakens it. Given all the other pressures on us right now, is that what we really want?
Whilst you correctly pointed out declining marriage rates overall, there is evidence to suggest lower divorce rates in states that have legalised same-sex marriage.
Needless to say, I will be voting yes.


text:
with Anna Campbell
Tues 3/3 Silver clay ring making
12/3-15/3 You Can Make It residential metal clay conference, Dorset, England
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domain: artistic


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Expanded metal mesh sheet is fabricated with a regular pattern of diamond-shaped openings. These openings reduce the weight and cost of the sheet and provide ventilation, making it a versatile solution for many applications. The most common metals used for expanded metal sheet include steel, stainless steel, and aluminum, although it is also made from titanium and copper.
How is Expanded Metal Sheet Manufactured?
Expanded sheet is made from a single sheet of metal slit by a row of knives mounted on an industrial die-cutting machine. The blades move back and forth in a uniform pattern, slicing the sheet in alternating cuts while the sheet moves through the machine.
As the knives cut, they simultaneously push down on the newly cut sections, stretching them apart into “ribbons.” The ribbons remain attached to the uncut sections, which become the corners of open diamond shapes in an expanded mesh sheet. The knives' size, shape, positioning, and thickness of the metal sheet can be changed to create openings of different dimensions for various applications.
Expanded Metal Sheet OptionsExpanded metal mesh sheet is available in several unique options to provide the features your project requires; it’s available in several individual profiles, including:
Standard Expanded SheetRaised expanded metal sheet is a finished product when it comes off the press after being cut and expanded. Raised expanded metal sheet features alternating ridges formed by overlapping metal strips that create a diamond pattern. The expanded metal sheet’s diamond pattern helps to permit air circulation. Standard metal sheets can be produced in various sizes and weights, which can be used when making lockers, warehouse fencing, and machinery safety doors.
Flattened Expanded SheetFlattened expanded sheet is about 5% lighter than standard expanded sheet and is cold rolled, leaving a flat, smooth surface. The cold rolling process flattens the metal and helps to make it flatter, thinner, and longer. Flattened expanded sheet’s slip-resistant coating makes it ideal for construction walkways and stairways. It can also be used for fencing, décor, and ventilation applications.
Expanded Metal GratingExpanded metal grating has no joints or welds and is heavier than standard expanded metal mesh products, as each sheet is a single piece of sturdy steel. Expanded metal grating is ideal for catwalk, stair, and platform applications, providing an outstanding strength-to-weight ratio. Expanded metal grating is one of the most solid and cost-effective expanded metal sheet products available.
Benefits of Expanded Metal SheetExpanded sheet metal is a versatile and economical product that is durable, easy to work with, and provides low wind resistance. It offers one-piece construction that won’t unravel under normal circumstances and will hold its shape for many years. The strands and bonds of the diamond-shaped trusses add strength and rigidity. Additional advantages include:
- High strength
- Corrosion resistant
Expanded Metal Mesh ApplicationsSteel expanded metal sheet is commonly used for the following applications:
- Machine guards
- Catwalks, platforms, and stair treads
- Stair and balcony railing mesh
- Window security
- And much more
Expanded Metal Material OptionsExpanded sheet is available in standard (raised) or flattened diamond patterns, in various gauges, opening sizes, and sheet sizes. Materials we stock include:
The IMS DifferenceWhat separates IMS from other metals companies? With an abundance of metal options and customer service that is second to none, IMS has you covered with the following advantages:
- Next-day delivery of processed material via our trucks
- Same-day pick-up in Will-Call
- No minimum purchase
- Support of Just-in-Time manufacturing processes
- Salespeople that act as an extension of your purchasing department (we will get any metal products you need)
- Material management (stocking and delivery on a scheduled basis)
- Credit lines with good terms
- Knowledgeable staff that knows metal
- Seven stores are open six days a week (check each location for specific times)
- Shop by metal alloy


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If you ask people if they would like to survive in a disaster situation, every one of them would tell you yes, obviously. But if you ask them how many of them are actually prepared, you’d see maybe only a third of them (and that’s being generous) would say they were.
While everyone wants to survive, not everyone will actually work a plan to make sure that happens. There are always a variety of reasons that people give for not preparing.
Topping the list is always the excuse that putting a survival plan in action costs too much money. So they don’t prepare. They believe that the government will step in and help them.
What they fail to realize is that the government isn’t in the position to help people in the event that a disaster is catastrophic. Sure, the government can step in and help if an area or two is hard hit – but we saw how well that went in Katrina and other disasters.
But imagine a disaster of such proportions that it astounds the entire world. If something like an Ebola crisis began to hit hundreds of thousands of people in every city and in every state.
The government wouldn’t be able to keep up. If you weren’t infected and had to stay quarantined in place, you would become one of millions. How well do you think your needs would be met?
Are you financially prepared for a natural disaster?
You can’t afford to rely on anyone else and you can’t afford not to prepare. Learn how to make a plan with CFPB’s tips: https://go.usa.gov/xPbJv
The problem that most people have when they use the excuse that they can’t afford to gear up for survival is that their outlook is far too broad.
They’re looking at a list of supplies as a whole rather than breaking them down and concentrating on building up in small increments. You can set aside the supplies you need for survival even if you don’t have all of the money you need at once because you can do it on a budget.
Even if you live paycheck to paycheck, you can afford to prepare. What you have to do is buy just a few survival supplies each month. As each month passes, your store of supplies will grow. Set aside a small amount from each paycheck to go into your savings account. Find more tips to help you manage your money to be prepared for the unexpected: https://www.usa.gov/flec
Get Prepared Now!: Why A Great Crisis Is Coming & How You Can Survive It
Are you and your family prepared for the greatest economic collapse that America has ever seen? Economic expert Michael Snyder of The Economic Collapse Blog and Barbara Fix, author of Survival: Prepare Before Disaster Strikes, address the whys and the hows of getting prepared for the coming crisis in their new book. Topics include looming economic collapse, Ebola, drought and increasing weather-related disasters, our extremely vulnerable power grid, civil unrest, and practical steps for storing food and supplies that you will need.
Concentrate on reaching small goals first.
For example, you can prepare for a 72-hour emergency first. So what you do is focus your money on buying just what you need for each member of your family to live for three days.
Once you have those supplies, then you gradually increase what you have – such as preparing for enough food for a week – and you slowly increase those supplies to make sure you have enough for two weeks, and so on.
You can find ways to add money to your budget by cutting out things that you don’t absolutely have to have right now just until you get your supplies built up. Budget for everything and don’t waste money.
Use coupons – especially the buy one get one free coupons. Always shop for sales for your food and supplies. Sell some of the items that you have around your home that you don’t need or no longer use and then put that extra money toward building up your supplies.

domain: economics


The Philippines receives so much more solar energy than all other energy sources and this could have supplied a huge percentage of our country’s electricity needs if only we have the knowledge and resources for solar power electricity.With only two seasons in the Philippines, the wet and dry seasons, we are in a geographically favorable area for solar energy use. We have constant sunlight almost every day even if it gets rainy. And if the sun’s energy is used well, we could save a great deal on our electricity bills and also help our environment.
Solar Power for Homes
A number of homes in the Philippines have already started going solar in recent years. Because of its reputation as a clean and renewable energy source, many have grown interested in solar power for home electricity. However, a lot of people still lack information about this sustainable energy source.
Here are some benefits of having a solar powered home to help you decide on using it.
- It helps you save money. Electricity costs from power companies make up a huge percentage of your monthly bill. By using solar energy, it can cut your electric bill by half or more depending on the size of your solar power system.
- It provides you with a reliable energy source. Using the sun’s energy is quite reliable since the sun is a constant element in our lives. We know when it will rise and set. Therefore, we know how to use it to our advantage.
- It protects you from increasing electricity costs. The sun is a readily available source of energy and it is very sustainable. With its use on your home, you will not or just be limitedly affected by the unpredictable rise of electricity rates for at least 15 years.
- You help others because installation of solar panels creates jobs. The solar power industry is a powerhouse for job seekers.
- It helps the environment by decreasing carbon output. It creates electricity without the pollution that causes global warming, and it is clearly one effective way of stopping this global crisis.
These are just simple explanations of what we gain by using solar energy. Solar energy companies, such as SOLREV Energy, will be ready to assist you and give you more information should you ask for it.
is the Western Pacific’s fastest growing supplier of solar panels. They are committed to educating the public about the sun’s energy and how it can affect lives. Visit them for more information on this.


From Brigitte Bardot's beehive to Mary Quant's geometric prints, signature styles from the 1960s have played a crucial part in influencing fashion as we know it today.
Thanks to Marc Jacobs, the 60s trend is well and truly back for Spring/Summer 2013. At both the Louis Vuitton and at his own S/S 13 show, bold colour palettes, short hemlines and strong prints - namely stripes and checks in monochrome - were prevalent, with a particular focus on linear lines and symmetry on the Vuitton catwalk.
And while the likes of Audrey Hepburn and Jane Birkin will always remain two of the decade's greatest style icons, the V&A museum is currently paying tribute to another big star of the decade with its David Bowie retrospective.
So - as 60s style is still in full swing in 2013, here's a reminder of iconic fashion moments from the era:


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Obamacare prompts one insurance agency's hiring spree
While many business owners have expressed concerns that health reform would lead to job losses, the Affordable Care Act has directly led at least one Portland area company to rapidly staff up.
VelaPoint LLC, an independent insurance agency, is looking to hire 139 people in the next 45 days.
“The ACA, in my world, is certainly shaking things up,” said VelaPoint COO Andrew Pibal. “We are hiring a lot of people as a result of the ACA.”
VelaPoint is looking for certified life and health insurance agents, along with customer service representatives.
A few months ago, there was a lot of concern in the agent community that the state health exchange would push their profession into extinction, just like Expedia and Travelocity hit the travel agency industry. However, that prediction appears to be far from the case.
Cover Oregon is looking to train up to 2,000 agents to assist individuals and small businesses in navigating the site, finding the right policies for them and signing up for coverage and potential tax credits. About 1,000 agents and 800 community partners already have been trained.
About 95 percent of small businesses go through an agent to buy group insurance plans, which can be a complicated process involving all sorts of calculations, especially in the new era of health reform.
Rocky King, Cover Oregon’s executive director, has said that the exchange needs people in local communities who already have relationships and have trust, since a central call center would be hard pressed to handle the thousands of calls that are expected to come in.
“From day one, we’ve said agents will play a significant role,” King has said.
Elizabeth covers health care for the Portland Business Journal. Sign up for her Health Care Inc. NW newsletter to keep tabs on what's happening in the rapidly changing industry.
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Life can sometimes be hard. There are days when we feel so lethargic; where all we want to do is lay on the bed, doing nothing the whole day. We may take a day off from work or for that matter waste our Sundays doing nothing! Sure, our bodies get the rest they demand but what about the mind?
Our mind is constantly working to keep generating thoughts. Even as you read this, numerous thoughts are running in your head. Aren’t they? See, that’s why it is important to relax your mind and snooze your thoughts each day, even if it is for a little while. After all, relaxation is everybody’s right.
Here, I am sharing with you 5 ways to calm your mind. Oh, and don’t worry, no coach required! You can do these on your own. These work for me every time, and I am pretty sure these will be effective for you as well. Read on to know more!
How to Calm Your Mind Instantly?
- Listen to music
Music heals everything. Feeling tired? Listen to music! Feeling restless? Listen to music! Lie down on your bed/sofa, or recline on a chair, plug in your earphones, play your favorite playlist, close your eyes, and enjoy. Let the music speak to you. Let go of everything and immerse yourself completely in the vibe. Do not think about anything. Just keep enjoying the moment. And then, when you will open your eyes, you will find yourself smiling, because you will be at peace. Your mind will be at peace. And FYI, listening to music is one of the proven ways of stress management.
- Write down 5 things that you are grateful for!
Now, come on! Everybody can list at least 5 things that they’re grateful for. For instance – I am grateful for (1) today, (2), I am healthy, (3) I can read and write, (4) I am blessed with all the necessities, and (5) that a wonderful soul like you is reading my blog.
When you take time to focus on the good things in life, you become more positive and you become happier. This technique contributes tons to the reduction of stress. Whether you are under emotional stress or work stress, try writing down at least 1 (if not 5) thing that you are really thankful for. Trust me, gratitude is good for us!
‘Mens sana in corpore sano’, meaning ‘A healthy mind in a healthy body.’ A phrase that we all have studied in school. Perhaps, it’s time to learn it now. Physical exercise is an important part of mind and body wellness.
It isn’t necessary to do strenuous exercise to release stress. You can simply take a walk or jog around or you can do it in the most fun way – DANCE like no one is watching you. This releases happy hormones – dopamine, oxytocin, serotonin, endorphins, that are good for your body and mind. Exercising daily leads to stress reduction and improves your well-being.
This is by far the best mind therapy. Just breathe in and breathe out. Pay attention to your breath. When your attention wanders, recollect yourself and return to focusing on your breath. This is known as Mindfulness Meditation. Do it for 15 minutes every day and your stress will be reduced. Besides, it also helps in lowering blood pressure, improves sleep, lessens gastrointestinal difficulties, treats heart disease, and more.
Amidst our busy schedules and demanding lives, I believe meditation is necessary. An old Zen saying suggests, “You should sit in meditation for 20 minutes every day – unless you’re too busy. Then you should sit for an hour.” All kidding aside, it is best to start with 5 minutes or 10 minutes or 15 minutes, and then gradually increase the span as per your convenience.
Here is an easy breathing exercise for you-
- Inhale slowly through your nose, and keep your shoulders relaxed. Your abdomen should expand but your chest should rise a little.
- Exhale slowly through your mouth. You may purse your lips a little, but keep your jaw relaxed.
- Repeat. Do it for several minutes until you start feeling better.
- Hang out with a dog
Spending just a few minutes with your four-legged friend lowers anxiety, and increases the levels of dopamine and serotonin – two neurochemicals that play a major role in developing a happy mind. Moreover, playing with a pet, especially dog staves off depression. Studies show that spending time with your dog decreases the levels of cortisol – a stress hormone, and increases the production of serotonin – a happy hormone, in your body. In fact, simply watching your dog may prove to be beneficial for your mental health.
So, these were the top 5 ways that are guaranteed to calm your mind. Other ways to instantly relax your mind are having your favorite chocolate, splashing cold water on your face, getting a head massage, or taking a cleaning spree. Anxious thoughts can overwhelm you, and you might feel exhausted all the time. Anxiety may also lead to overthinking which in turn may make you more anxious. Thus, it is very important to step out of this vicious cycle.
Often, in order to maintain calm, many people ignore or avoid anxious thoughts. But that won’t work in the long run. Because these thoughts will recur. Trust me! The right solution is to find the techniques that will be effective in healing your body and mind in the long run. So, listen to your favorite music, dance like no one’s watching, meditate, write down your worries, and spend some time with your furry friend. And you will soon observe the positive effects on your mind. So, which ways are you going to adopt? Let me know in the comments. I’d also love to know how you cope with anxious situations? What are your go-to options to calm your mind? Keep the comments coming!


Smallbore, pistol cartridge, centerfire - revolvers, pistols, Contenders, etc...
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I'm curious what has happened with IHMSA? You have to have a moderator "approve" your posts...can't even post match schedules. The presidential post is some sort of catty diatribe about motel rooms, is the sport really that far gone? I'm looking forward to a season of shooting.


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Agri 2312 chapter 17 exchange rates and agricultural trade
Exchange Rates and Agricultural Trade Chapter 17
Discussion Topics

Exchange rates and the foreign exchange market

The balance of payments

The international monetary system

Exchange rate determination

Exchange rates and U.S. agricultural trade

Considerations for policy coordination

Exchange Rate Defined The exchange rate is the number of units of a foreign currency required to obtain one unit of a domestic currency. The reciprocal of this rate expresses the number of units of a domestic currency required to obtain one unit of a foreign currency. These rates can be thought of as the value of the domestic currency relative to a foreign currency (i.e., the value of the $ relative to the £ or ¥ ). Page 335
Page 337 When the value of the dollar appreciates in value, the exchange rate index increases. A depreciation of the value of a dollar causes the index to decline.
Page 337 The line “Canadian dollar (in U.S. dollars)” of 1.305 means that a Canadian dollar exchanges for almost $1.31 in U.S. currency. One British Pound is worth about $1.82 in U.S. currency.
Balance of Payments The balance of payments (BOP) is made up of three main accounts: Current account: composed of merchandise trade account (exports less imports), services trade account (income from international capital investments, tourism, transportation and insurance) and transfer payments (gifts and foreign aid). Private capital account: summarizes transactions in real and financial assets and foreign activities of U.S. banks. Official settlements account: summarizes net changes in official holdings of international reserve assets. Page 338
Page 341 The U.S. began running a current account deficit in the mid-1980s as a result of a growing merchandise trade deficit. Inflows of private capital were used to pay for this deficit. Private capital account Current account
Page 345 Only 25 countries, including the U.S., Japan and Canada allow their currencies to float independently. Most countries peg or “fix” their Currency relative to another currency, basket of currencies or SDRs.
Page 347 Rates are determined by forces affecting the supply and demand for currencies on the foreign exchange market.
Page 348 An increase in the demand for dollars as U.S. interest rates rise, indicating here that it takes 4 euros to buy a dollar rather than 3 euros. E 5 E 4 E 3 E 2 E 1 Exchange rate (Euros/dollars)
Page 349 A trade deficit causes an increase in the supply of dollars on currency markets, thereby weakening the dollar and lowering the exchange rate from 3 euros per dollar to 2 euros Exchange rate (Euros/dollars)
Page 351 When the dollar rises, exports fall, and when the dollar declines, exports rise.
Page 352 An increase in the value of the dollar makes Our exports more expensive to client nations.
Summary

Exchange rates have an impact on U.S. agricultural trade.

The value of foreign currencies is determined in the foreign exchange market.

Balance of payments is a link between international trade, capital flows and exchange rates.

The international monetary system is called a managed float , where rates fluctuate within limits controlled by the International Monetary Fund or IMF .

Chapter 18 discusses the reasons why nations trade ….

domain: finance