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Clodia Osipo, PhD
Associate Professor of Cancer Biology and Microbiology and Immunology
Graduate Program Director: Molecular and Cellular Oncology, Co-Leader of Breast Cancer Program
Loyola University Chicago
Goal: To prevent resistance to treatments for estrogen receptor (ER)-positive and triple-negative breast cancer (TNBC).
Impact: Breast cancer stem cells (BCSCs) are the cells believed to allow breast cancer tumors to resist treatment. Drs. Osipo and Albain are studying a gene called DAXX that blocks BCSCs. The team is investigating how DAXX affects a patient’s response to chemotherapy, as well as other cancer fighting drugs, including PARP-inhibitors that used to treat some triple-negative breast cancers (TNBC). Their work may reveal a way to increase DAXX expression in breast cancer cells and improve patient survival.
What’s next: The team will focus on the role of DAXX as a breast cancer suppressor and as a predictor of response to therapies in both ER-positive and triple-negative disease.
While breast cancers that rely on estrogen for growth can be treated with endocrine (anti-hormone) therapy, resistance to this treatment often develops. Drs. Osipo and Albain are studying a potential biomarker called DAXX that may predict response to endocrine therapy in patients with ER-positive breast cancer. They are also investigating high DAXX expression in TNBC, which appears to improve response to standard chemotherapy and a class of targeted drugs called PARP-inhibitors.
Full Research Summary
Research area: Developing strategies to block the survival of dormant breast cancer stem cells in order to improve patient outcomes.
Impact: Estrogen receptor (ER)-positive breast cancers are treated with endocrine therapy, such as tamoxifen or aromatase inhibitors. While these therapies are effective, resistance remains a major challenge. Drug-resistant tumors continue to grow and are more likely to spread to other organs (metastasize). Drs. Osipo and Albain have discovered several novel pathways that appear to be very important for the survival of breast cancer stem cells—the cells most likely to survive anti-cancer therapies and cause breast cancer recurrence many years later. Their efforts may inform the development of new strategies to block survival of dormant cancer stem cells and reduce drug resistance in ER-positive and triple-negative breast cancer (TNBC).
Current investigation: The team has been investigating novel cancer stem cell biomarkers that can predict the potential for response to treatment as well as resistance to therapy. Their most recent work has been focused on the biomarker DAXX.
What they’ve learned so far: Drs. Osipo and Albain have identified DAXX and Notch as key pathways in the resistance of BCSCs to cancer treatment. Their studies have shown that high amounts of the DAXX gene correlates with a reduction in the number of BCSCs and a better response to endocrine therapy, standard chemotherapy, and PARP-inhibitors in ER-positive and triple negative breast cancer cells. In addition, they have shown that phytoestrogens found in some food products increase the expression of the DAXX gene resulting in a decrease in BCSCs.
What’s next: Drs. Osipo and Albain will now examine breast cancer tissue before and after pre-surgical therapy to determine if the levels of DAXX and other biomarkers predict long term survival in estrogen receptor-positive disease. They will also continue their studies to determine how DAXX can regulate and predict the tumor’s response to chemotherapy and/or PARP-inhibitors in ER-positive and TNBC.
Dr. Clodia Osipo received her PhD in Molecular and Cellular Biochemistry from Loyola University in 2002 while working under Dr. Allen Frankfater. Thereafter, she did her post-doctoral fellowship at the Robert H. Lurie Comprehensive Cancer Center of the Feinberg School of Medicine at Northwestern University. Dr. V. Craig Jordan, the principal developer of adjuvant tamoxifen therapy for estrogen receptor positive breast cancer, was her mentor. Dr. Osipo's research under Dr. Jordan focused on investigating the role of HER2/neu, the second member of the epidermal growth factor receptor family, in breast tumors that had acquired resistance to tamoxifen in vivo. Dr. Osipo has published numerous articles, reviews, and book chapters on tamoxifen and other selective estrogen receptor modulators and downregulators. She joined Loyola University Chicago as an Assistant Professor in 2005. She is currently an Associate Professor of Pathology with tenure and the co-leader of the breast cancer program with Dr. Kathy Albain, MD. Dr. Osipo's research focuses on elucidating the role of Notch signaling in resistance to anti-estrogen and HER2-targeted therapies in breast cancer.


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Urban Reviews is the premier destination for all things relating to African-American Fiction. It's primary focus will be on the promotion of new and upcoming books by Black authors, but Urban Reviews will also include exclusive interviews, online Q&As, tour info, press release info, and industry news as well.
Saturday, February 25, 2023
New Review : The Black Magician : KayCee Jones
4 out of 5 books
When the ancestors were stolen from Africa, the slave catchers were taking kings, queens, princes, princesses, and doctors. Highly intelligent individuals who carried their knowledge, secrets and gifts with them to America. THE BLACK MAGICIAN is a tale that portrays the strength, intelligence, and resilience of those who are enslaved. George is such a person, gifted with the ability to read the aura of individuals, he uses this to identify slaves who are mentally strong and highly desire freedom from the bonds of slavery.
With the aid of his grandmother, affectionately referred to as “Granny’ by all, George learns the history of his people, the power he possesses and the secrets of plants and herbs that she learned from her ancestors who were doctors and scientists. George’s responsibility on the plantation is as a blacksmith. He is recognized by his master for the inventions he made that the master is secretly patenting and selling as his own inventions to maintain income for his plantation. With the help of Indian Red, Master Smith’s lovechild, Shelby who is an abolitionist in Philadelphia, George’s ability to make things with his hands and Granny’s secrets to deceive and escape the slave catcher, those who desire are able to taste freedom.
I enjoyed this book because most people don’t recognize the intelligence and ability of our enslaved ancestors. They were not able to display that knowledge for fear of retaliation, not recognizing that they gathered slaves from different tribes together on plantations so that they can’t speak to each other, and they lack the ability to read the English language. Therefore, there was no means to carry on their native language to future generations. The book shows how they overcome those barriers to discern and know that they can one day be free.

domain: library


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Detroit Tigers catcher Alex Avila played his first game in his rehabilitation stint with the Triple-A Toledo Mud Hens on Monday night. He went 0-for-2 in five innings, with a fly out in the first and a strikeout in the third.
After the game, Avila said his time in the minors isn't as much about getting healthy as it is about getting ready, via Chris Iott of mlive.com.
"I knew coming into today from what I was doing in Detroit over the weekend that my hamstring was good," Avila said. "I just wanted to make sure I could get it to where I can go 100 percent not thinking about it. The reason why I'm here early is because I was able to get to that point.
"Now, it's just about getting back into a nice rhythm at the plate and seeing some pitches, taking some balls off the chest and building up some bruises and stuff like that."
Avila was placed on Detroit's disabled list on June 6 with a hamstring injury. He is set to catch five innings again on Tuesday, DH on Wednesday and return to the Tigers on Thursday.

domain: news


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The next stage of my plan is to start plodding through the other bags of unfinished stuff. Yesterday I blocked the Harmony Shawl and the Tea Time doily, so that's two finished objects already!
Also yesterday I finished this jar cozy, which is available to buy on Buy British Month on CNA:
And I have a few yarn bargains listed on there too, so head over and check them out.
Of course I haven't managed to get much else done with the lovely sunshine today. We've been having some bubble fun:
Then lunch included dinosaur sandwiches:

domain: artistic


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Questions for LGBTQ Worldmaking
Edited By Dustin Bradley Goltz and Jason Zingsheim
Section IV: Questioning the Limits of Decorum: Strategies for Assimilation, Interrogation and Radical Transformation
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Questioning the Limits of Decorum: Strategies for Assimilation, Interrogation and Radical Transformation
From the tensions of coalition, we move to explore the limitations and hegemonic workings of normative affects—socially acceptable expressions of emotion—particularly their intersectional collusions with whiteness and patriarchy. This section delves into the potentials and shortcomings of queered anger and queer decorum as alternative sites for queer political engagement. Suspicious of the disciplinary functions of calmed and institutionalized rationality, we process how the maintenance of decorum and the containment of anger can mask the symbolic and material violences that anticipate, vitalize, and fuel queer politics. Yet, we also examine how breaches of decorum and invocations of anger can function to both mobilize and/or erode support for queer political goals. Further complicating the role of these emotional expressions are the racialized and gendered histories and standpoints that inform their performances, embodiments, and receptions. Does queer resistance ever not violate normative affective registers? Is there such a thing as queered decorum? Is (queer) decorum always tied to normative assimilationist politics? Is there potential resistance in minimized affect? Is there queer love or a queer politic without anger? What are the temporal components of anger and decorum?
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domain: literature


The UK Ministry of Defence has distanced itself from any possible future use of the BAe 146 as a refuelling tanker, following the concept’s recent promotion by BAE Systems Regional Aircraft.
“No assessment has been made of the air-to-air refuelling capability of the BAe 146,” said minister for defence equipment, support and technology Philip Dunne in response to a parliamentary question on 8 October.
“The department has identified [UK defence] requirements for air-to-air refuelling. This concluded that [the Airbus A330] Voyager will meet all air-to-air refuelling requirements.”
A core fleet of nine Voyagers will replace the Royal Air Force’s remaining Lockheed TriStar tankers and retired Vickers VC10s, with six of the AirTanker-supplied type now in service.
BAE unveiled an offer to modify the 146/Avro RJ regional airliner for the tanker role during the DSEi exhibition in London last month. The company, which has already supplied two military transport-adapted C3-model aircraft to the RAF, says the type could be equipped with a hose drum unit and auxiliary tanks, enabling it to transfer up to 18t of fuel.
A first proximity trial was performed in 2009 using an RAF Hawk T1 trainer to investigate the concept’s feasibility.
Source: Flight International


A business group within the World Wide Web Consortium (W3C) is planning to ask Google to delay the third-party cookie phase out in Chrome in light of the ongoing coronavirus situation.
A member of the group told AdExchanger that the plan is to request that Google extend the deadline, which was tight and somewhat tentative to start with, by between six and 12 months. The petition could be sent as soon as early April.
The request for an extension is an item on the draft agenda of the W3C’s Improving Web Advertising Business Group, which has its next meeting scheduled for March 26. The draft agenda also includes a potential discussion about the business challenges and use cases behind the group’s appeal.
Google announced its plan in mid-January to eliminate third-party cookies in Chrome by 2022. At the time, coronavirus awareness in the United States was still on the periphery.
Rearchitecting the cookie-based ad ecosystem in two years was a tall order regardless of the outbreak, and the business disruptions it has caused simply ratchets up the pressure.
To date, Google hasn’t been more specific on its plans for timing other than to say that conversion measurement and interest-based advertising will be the first two issues it’s planning to address through the Privacy Sandbox. In January, Google said that trials for click-based conversion measurement (minus third-party cookies) would start by the end of the year.
It’s entirely possible that the Chrome folks will be open to an extension. It’s not all that unreasonable a request considering what’s going on in the world. Then again, Google is a multiheaded beast that operates in distinct silos. The Chrome team works independently from the Google advertising team, and one group might have less sympathy than the other.
The W3C is an international group that develops standards and protocols for the web. Nested underneath the W3C umbrella are hundreds of business and community groups which provide a forum for developers, designers and other industry stakeholders to hold discussion and propose ideas in a vendor-neutral way. The Improving Web Advertising Business Group is one such entity.
The group includes 136 members from across the ad industry spectrum, including MediaMath, Rubicon, Taboola, Neustar, Apple, Google, Amazon, Facebook, Adobe, Criteo, Salesforce, CafeMedia, IAB Tech Lab and eyeo GmbH.
According to its mission statement, the group’s purpose is “to identify areas where standards and even changes to the web itself can improve the ecosystem and experience for users, advertisers, publishers, distributors, ad networks, agencies and others, and to oversee liaison with existing working groups.”


text: The other day, a friend of mine dropped in. It was more than a decade since I saw him last. I extended him a hearty welcome and asked him to take a seat. He sat down and his eyes sized me up to my utter discomfort. ‘My god’ he said at last. The conversation started. ‘You must be at least 15 kgs overweight’ he told me after giving me a look from top to toe. ‘You must knock it off your system as quickly as possible’ he added. ‘Do you think so?’ I asked him. ‘Everyone who looks at you will think so’ ‘You are also liberally endowed though not as liberally as I am’ ‘I am just 2kg overweight’ he answered me. Liar! ‘Let us stop this mutual weighing game. With all that fat you are carrying, you are on your way to disaster’ ‘What disaster?’ ‘At your age, every kg of excess weight means one year knocked off your life span’ ‘So for 15 kg overweight, should I multiply it by 15?’ ‘Cut all that crap. Can’t you see I am serious?’ ‘If I reduce my weight by 20 kgs, will I live beyond 100?’ ‘Tell me, what are you eating everyday’ ‘Food’, I said. I could see his blood vessels knotting themselves on his forehead. ‘Ok, ok, I eat rice with the usual paraphernalia.’ ‘Three times a day?’ ‘It would be four times on Sundays and holidays declared by the government’ ‘At your age, you must take life a little more seriously. You must cut down rice and eat millets’ “But I don’t like their colour’ I like pure while things like polished rice’ ‘Polished rice is great disaster. When it concerns your life, don’t be too colour consciouses’ ‘I am not. When I was young, I wore shirts of all hue. I used to be a trendsetter. I was the first one to introduce bleeding Madras cloths in the college’ “We are talking about food’, he reminded me. ‘Do you eat papaya?’ he asked me. ‘You mean those shapeless fruits?’ ‘They may be shapeless but they are good for your shape and health too’ ‘How many glasses of water you drink daily?’ he went on with his probing into my dietary habits. ‘I don’t keep a count. Three glasses a day perhaps’ ‘At three glasses a day, you would have died of dehydration long back in Chennai heat’ he said and laughed at my stupidity. ‘Plenty of water will help you to lose weight by keeping your system clean’ ‘You know there is serious water shortage in this area. We have been advised to take bath once in two days and drink not more than four glasses of water daily’ ‘I know there is that problem’ he admitted condescendingly. ‘I think we should discuss all these health issues only after the water situation eases here’, I said in an effort to divert his mind from my fat torso. ‘Do something about your size’ he advised me and rose up to leave. He loosened a button in his shirt as he rose and said that it was stitched long back. ‘Shirts tend to shrink over a period of time, you know’ he added smilingly and took leave of me.


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The United boss is keen to add more firepower ahead of next season, and now faces the task of replacing Zlatan Ibrahimovic, who is set for a lengthy spell out with knee ligament damage.
And Don Balon claims that Mourinho hopes his good relationship with the Real Madrid officials can help him get a deal done for Morata, who has scored 19 goals in 40 appearances for club and country this term.
The 24-year-old Morata has struggled for starts under Zinedine Zidane, and would reportedly favour a move elsewhere in search of more game time.
Chelsea are also said to be keen, but Mourinho hopes his friendship with Florentino Perez will give United the edge.
Meanwhile, United are 'confident' of securing a summer deal for Valencia midfielder Carlos Soler, according to the Daily Star.
The 20-year-old has impressed in La Liga and Valencia are trying to tie him down to a long term contract.
He currently has a £25m release clause, and United are reportedly ready to pay that figure to sign the Spanish youth international ahead of 2017/18.
Get all the latest Manchester United news first with our new app. Download it here now.


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CARSON (AP) - Chris Wondolowski scored in the 87th minute and the short-handed San Jose Earthquakes kept their playoff hopes alive with a 1-0 win over Chivas USA on Sunday night.
ANAHEIM (AP) - Dan Boyle scored two power-play goals, Joe Pavelski and Patrick Marleau each had a goal and an assist, and the San Jose Sharks beat the Anaheim Ducks 6-5 Saturday night in the teams' preseason finale.
SEATTLE (AP) - Bartolo Colon outpitched Felix Hernandez to reach 18 wins for the fifth time in his career, Brandon Moss hit a three-run homer in the first inning and the Oakland Athletics beat Seattle 6-2 Friday night in the start of Eric Wedge's final weekend as Mariners manager.
SAN FRANCISCO (AP) - Hunter Pence hit his career-best 26th home run to back a shaky outing by Ryan Vogelsong and the San Francisco Giants beat the San Diego Padres 7-3 Friday night.
SANTA CLARA (AP) - The San Francisco 49ers turned a short week of negative energy into their first blowout victory of the season.
OAKLAND (AP) - The opening month of the season hasn't quite gone as planned for Robert Griffin III and Matt Flynn.
• TIGER PGA TOUR'S TOP PLAYER: Tiger Woods was voted PGA Tour player of the year for the 11th time on the strength of his five big wins and return to No. 1 in the world. It was the third time Woods won the Jack Nicklaus Award despite not winning a major. He made up for that with two World Golf Championships and The Players Championship among his five wins.
SAN JOSE (AP) - The San Jose Sharks will be without forward Raffi Torres for the start of the season because of an injured right knee.
CHICAGO (AP) - The Pittsburgh Pirates are headed to the playoffs for the first time in 21 years, clinching at least a National League wild card Monday night when they beat the Chicago Cubs 2-1 and the Washington Nationals lost to St. Louis.
ANAHEIM (AP) - Not even Sunday's champagne-soaked celebration of another division title could knock the Oakland Athletics off their soaring trajectory toward the playoffs.
SANTA CLARA (AP) - The San Francisco 49ers are prepared to go forward without star linebacker Aldon Smith for as long as it takes for him to get clean, healthy and improve his life.
The larger-than-life figure that teased and tormented the Sacramento Kings for so long is now the biggest name to join the franchise's new ownership group.
DENVER (AP) - Peyton Manning slapped his hands together five, six, seven times and barked out the signals. A few seconds later, Wes Welker was all alone, cradling the quarterback's latest touchdown pass.
OAKLAND (AP) - Wearing a gold robe and swim goggles, bearded right fielder J2osh Reddick ran around the Oakland Athletics clubhouse guzzling beer as bubbly sprayed in every direction.
DENVER (AP) - Oakland quarterback Terrelle Pryor has seen the scores. Peyton Manning and the Denver Broncos have put up 40-plus points in their first two games and made offense look easy.
ASH, England (AP) - Defending champion Graeme McDowell and Victor Dubuisson began the World Match Play Championship with comfortable wins on Wednesday, three weeks after teaming up as one of Europe's top pairings in the Ryder Cup at Gleneagles.
KANSAS CITY, Kan. (AP) - Abby Wambach scored in the 54th minute to help the United States beat Trinidad and Tobago 1-0 on Wednesday night in their opening Women's World Cup qualifying game.
NEW YORK (AP) - As he nears yet another milestone, Peyton Manning has the Denver Broncos back as the top team in the NFL.
SAN FRANCISCO (AP) - Hall of Famer Willie McCovey returned to the ballpark Tuesday for Game 3 of the San Francisco Giants' NL Championship Series win against St. Louis after being released in recent days from a lengthy stint at Stanford Hospital.
NFL Commissioner Roger Goodell and players' union chief DeMaurice Smith agreed to continue discussing changes to the league's personal conduct policy following a four-hour session in New York on Tuesday.
SAN FRANCISCO (AP) - A wild pitch, a wide throw and an 18-inning marathon.
After two decades of European dominance in the Ryder Cup, the Americans have created a task force to figure out why they keep losing.
CHARLOTTE, N.C. (AP) - NASCAR fined Brad Keselowski $50,000 and Tony Stewart $25,000 on Tuesday for their roles in the fracas at Charlotte Motor Speedway over the weekend.
KANSAS CITY, Mo. (AP) - The Kansas City Royals have embraced the bloop, bunt and sacrifice fly all postseason.
World Cup qualifying for the U.S. women's team looks like an easy road.
LOS ANGELES (AP) - Fresh off another early playoff exit, the Los Angeles Dodgers overhauled their front office Tuesday.
SAN FRANCISCO (AP) - As Barry Bonds hobbled to his car with the help of crutches post hip surgery, and well before the start of Game 3 of the NL Championship Series, the home run king insisted he can hardly remember the World Series of 12 years ago.
KANSAS CITY, Mo. (AP) - The last two times the Kansas City Royals played a postseason game at home, rain fell after the final out. This time, it started well before the first pitch.
ST. LOUIS (AP) - The San Francisco 49ers defense got beat early by unfamiliar plays and Austin Davis calling the signals.
ALAMEDA (AP) - Soon after taking over as interim coach of the Oakland Raiders, Tony Sparano had a simple message to deliver to quarterback Derek Carr: This is your team.


ADL Applauds the Virginia Senate's Rejection of Proposed Amendment Undermining Religious Freedom
Washington, D.C., February 22, 2005 … The Anti-Defamation League (ADL) today applauded the Virginia Senate's rejection of HJ537, a proposed amendment to Section 16 of Virginia's Bill of Rights, "Free exercise of religion; no establishment of religion."
The amendment would have undermined the free exercise of religion and the separation of church and state embodied in the First Amendment of Virginia's Bill of Rights. The proposed amendment was defeated 10 to 5 in committee.
"In rejecting this flawed amendment, the Virginia Senate has preserved Virginia's legacy as a cradle of religious freedom," said David C. Friedman, Director of ADL's Washington D.C. Regional Office. "We are pleased that the Virginia Senate chose not to tamper with the words of our founding fathers Thomas Jefferson and James Madison which have stood the test of time for over 200 years."
The Anti-Defamation League, founded in 1913, is the world's leading organization fighting anti-Semitism through programs and services that counteract hatred, prejudice and bigotry.


Water Repellent Cassian Parka - Final Sale
- A water repellent parka with a combo bib and rib knit collar to help you stay warm even in the coldest elements. For a thick warm parka, this jacket accentuates your curves by hugging you in all the right places. Stay warm and chic this coming season.
- Elasticated waist
- Detachable hood with vegan fur trim
- Front zipper closure with flap and snap closures
- Front pockets with flap and magnetic closure
- Inner pocket with media port
- Fits true to size
- Models are 5'9"-5'10" and wearing size XS
- Shell: 85% Polyester, 15% Cotton
- Lining and interior opening: 100% Nylon
- Fill: 100% Polyester
- Machine wash cold with like colours. Tumble dry low or hang to dry. Do not bleach. Do not dry clean.
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Monk & Lou
Vegan Leather Sandy Crop Jacket


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The Four Poster: Adapted from the prize-winning Broadway play that featured two people and a four-poster bed, in which the couple enacts their marriage, from its day in 1897, until he dies, some time after she has died from cancer. It is a "love" that endured wars, an "other" woman, and the death of their favorite son. The episodes are bridged and linked by cartoon sequences done by UPA (United Productions of America.)
|Ratings:||IMDB: N/A Metascore: N/A RT: N/A|
|Released:||October 08, 1952|
|Genres:||Drama Comedy Romance War|
|Actors:||Lilli Palmer Rex Harrison|
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Korbin Sims signs with England club Hull KR
November 20, 2020 12:30 pm
Korbin Sims [Source: Nine]
Fiji Bati forward Korbin Sims has signed a two-year contract with England rugby league club Hull Kingston Rovers.
The former Brisbane Broncos, Newcastle Knights and St. George star who appeared over 140 times in the NRL, will be making the move to Hull’s East Coast next year.
Sims says he is excited about the opportunity and to be able to play on England ground.
Let’s bang! 🤘🏽 https://t.co/B7rShmHvBg
— Korbin Sims (@korbinsims) November 19, 2020
The 28-year-old powerhouse says playing for Hull KR will help further his football career.
Tony Smith 🤝 Korbin Sims
A new fans favourite inbound. 🛬 pic.twitter.com/IB1Gh20OSe
— Hull Kingston Rovers (@hullkrofficial) November 19, 2020


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Sometime back I remember playing a free web game about a disease that kills everyone on the planet. It was fun, with the annoying bug that you couldn’t kill anyone in Madagascar. Then I heard yesterday about it’s spiritual successor, called Plague inc. I downloaded and found myself playing a lot of it overnight.
The plot is a bit of a twist – you are the disease. You want to kill every human being on the planet; or perhaps just everyone in Madagascar. As time goes on, you infect more and more people, start to kill, and will know the victory of destroying all human life, or failing by not doing so.
What makes the game fun are the decisions you make regarding how to mutate your virus. You select various attributes focused around deadliness, infection rate, disability, and special abilities. Evolve your virus the right way, and it could kill everyone.
My first game, I had experience with Pandemic, but not this specific game. I simply played without thinking much – use up all the DNA points that you gain, quickly, and see if it works on Casual Mode. I started in India and while I managed to kill around 80% of the worlds population, they found a cure and eliminated me.
Second game, I focused on being better at getting people sick. The infection spread faster but was still deadly – too deadly. I managed to kill off everyone who was sick, before the disease could spread to all humans. Fail.
Third game, I thought about the difference between wealthy and poor countries. The game warns you that you won’t spread very fast in a wealthy country with good healthcare. Well I said, screw it, let’s start in Japan anyway, focused on being an annoying virus that doesn’t kill anyone, and infected the whole world. Then I made it deadly, and all of humanity was destroyed. Win game.
It’s a lot of fun, and the minor grinding elements they’ve added are smart. You start as a bacteria only, but if you can beat the game on Normal mode, you get to try various other bugs. You can also unlock various buffs to your base virus. Well worth the $1 I had to spend to buy it.
Next time, I’ll try again to win on Normal mode. Hopefully I’ll do better than last time on Normal, where I wiped out the population except for Angola (!??), which defeated me by finding the cure..

domain: hobby


NEW ORLEANS (AP) — Doctors, listen to your patients and nurses. You can learn something.
Take Dr. Joseph Weber, a Mayo Clinic anesthesiologist. He listened, checked out what they told him, and came up with welcome news for coffee, tea and cola drinkers: One 8-ounce cup on the day of surgery is not just OK, but can be beneficial.
“I’d like to claim that I was some sort of genius and thought it all up,” said Weber, “but patients kept telling me and my co-workers, ‘If you’d just let me have a caffeinated beverage afterward, I’d feel a lot better.'”
“And nurses said, `We know patients are sitting around having headaches. We ask if they drink coffee every day. They say, `Yeah!’ and we give them a cup of coffee and they perk right up.'”
Weber designed a series of studies to check out what he was hearing: Were patients who consumed a daily dose of coffee, tea or cola — or, for that matter, Mr. Pibb or Mountain Dew — more likely to get headaches after surgery? Would a small drink before surgery hurt them? Would it help afterward? What about intravenous caffeine?
He presented findings from the studies — conducted at Mayo Clinics in Scottsdale, Ariz., and Rochester, Minn., — to the American Society of Anesthesiologists on Wednesday, the last day of its meeting.
“This isn’t a life or death issue. But we’re talking about millions of people who can be improved with a relatively simple and safe intervention,” Weber said.
He said 80 percent of all U.S. residents drink something with caffeine in it every day. It may be coffee (50 to 180 milligrams per 6-ounce cup), tea (11 to 60 mg), Jolt! cola (72 mg per 12-ounce glass), Coke (45.6) or Kick (31 mg).
His first study found that those people were more than twice as likely as most people to have headaches after surgery.
In general, 10 percent of all people come out of anesthesia with a headache. But Weber found that the chance rises to 25 percent for people deprived of their usual caffeine.
The second study found that 8 ounces of a clear caffeinated beverage two hours or more before surgery, on an otherwise empty stomach, does not appear to hurt anything. And, Weber said, it brought the chance of a headache back down to 10 percent.
His most recent study, of 234 patients in Arizona and Minnesota, found that either a cup of a caffeinated drink in the recovery room or a caffeine drip under anesthesia is just as effective.


AMD completes acquisition of Xilinx
— Transaction creates high-performance and adaptive computing leader —
— AMD to offer industry’s strongest portfolio of leadership CPUs, GPUs, FPGAs and Adaptive SoCs to address approximately $135 billion market opportunity —
SANTA CLARA, Calif., Feb. 14, 2022 (GLOBE NEWSWIRE) -- AMD (NASDAQ: AMD) today announced the completion of its acquisition of Xilinx in an all-stock transaction. The acquisition, originally announced on October 27, 2020, creates the industry’s high-performance and adaptive computing leader with significantly expanded scale and the strongest portfolio of leadership computing, graphics and adaptive SoC products. AMD expects the acquisition to be accretive to non-GAAP margins, non-GAAP EPS and free cash flow generation in the first year.
“The acquisition of Xilinx brings together a highly complementary set of products, customers and markets combined with differentiated IP and world-class talent to create the industry’s high-performance and adaptive computing leader,” said AMD President and CEO Dr. Lisa Su. “Xilinx offers industry-leading FPGAs, adaptive SoCs, AI engines and software expertise that enable AMD to offer the strongest portfolio of high-performance and adaptive computing solutions in the industry and capture a larger share of the approximately $135 billion market opportunity we see across cloud, edge and intelligent devices.”
Former Xilinx CEO Victor Peng will join AMD as president of the newly formed Adaptive and Embedded Computing Group (AECG). AECG remains focused on driving leadership FPGA, Adaptive SoC and software roadmaps, now with the additional scale of the combined company and the ability to offer an expanded set of solutions including AMD CPUs and GPUs.
“The rapid expansion of connected devices and data-intensive applications with embedded AI are driving the growing demand for highly efficient and adaptive high-performance computing solutions,” said Victor Peng. “Bringing AMD and Xilinx together will accelerate our ability to define this new era of computing by providing the most comprehensive portfolio of adaptive computing platforms capable of powering a wide range of intelligent applications.”
Upon close, Xilinx stockholders received 1.7234 shares of AMD common stock and cash in lieu of any fractional shares of AMD common stock for each share of Xilinx common stock. Xilinx common stock will no longer be listed for trading on the NASDAQ stock market.
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text:
Essential basics you must have in your wardrobe.
We have designed inner corsets so you can wear them under your dresses.
Enhance your waist whenever you want, even if you feel like not showing your corset.
We have also created fun satin bloomers or pantaloons.
Venture into a world of small details!

domain: design


text:
Tyrone wants Becky
“That’s a stereotype/Driven by some people up in Ariel Heights.” — J. Cole, G.O.M.D.
On an episode of his YouTube series entitled Cannon’s Class, actor, comedian, and rapper Nick Cannon met with Nation of Islam affiliate Rizza Islam to discuss Black men’s dating preferences. In what was a spirited conversation, Cannon proclaimed the following:
“White women are looked at as success, because in America we…

domain: celebrity


text: A 42-year-old fair-skinned woman requests a full body examination. Her medical history is negative for skin cancer, genodermatoses, and thyroid disease. She underwent lumpectomy for breast cancer 3 years earlier. On examination, scattered nevi and a flesh-colored nodule are noted on her upper back. The lesion is asymptomatic, and the patient is unsure how long it has been present.

domain: biology


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The Trump administration officially informed California about its plan to cancel nearly $1 billion in federal funding for the state’s high-speed rail project and to pursue legal action to get back $2.5 billion in funding, which was previously granted for the project.
Last week, President Donald Trump tweeted that California must return the federal funds given to the high-speed rail project after several media entities created confusion by reporting that Governor Gavin Newsom hit the brakes on the project.
In his State of the State address, Newsom said the state has the ability to complete the high-speed rail line between Merced and Bakersfield. However, right now, he doesn’t see a path towards the completion of the Sacramento to San Diego and San Francisco to Los Angeles lines. Some reporters and Republicans including Rep. Kevin McCarthy misinterpreted the governor’s statement that he is stopping the project. Thus, prompting Trump’s demand for the reimbursement of federal funds.
California fails to make reasonable progress on high-speed rail project
On Tuesday, Federal Railroad Administration (FRA) Chief Batory notified California High-Speed Rail Authority (CHSRA) Head Brian Kelly regarding the plan.
Batory told Kelly that the FRA intends to terminate its Cooperative Agreement (FR-HSR-0118-12-01-01) with the CHSRA effective March 5, 2019. After the termination, it will cancel the full $928.42 million in federal funding for the California high-speed rail project under the Agreement. The agency is also “exploring all available legal options” to recover the federal funds granted under the Agreement.
In his letter, Batory wrote, “FRA has determined that CHSRA has materially failed to comply with the terms of the Agreement and has failed to make reasonable progress on the Project…substantially endangering substantial performance.”
In addition, he said California’s decision to significantly change its plans for its high-speed rail system reinforces the FRA’s concern about CHSRA’s previous performance. Batory noted Newsom’s new proposal in his State of the State address is a “significant retreat” from California’s original vision and commitment for the project.
Newsom slams the FRA’s action as “political retribution” by Trump
Newsom immediately released a response to FRA’s action. According to him, “It’s no coincidence that the Administration’s threat comes 24 hours after California led 16 states in challenging the President’s farcical “national emergency.” The President even tied the two issues together in a tweet this morning. This is clear political retribution by President Trump, and we won’t sit idly by. This is California’s money, and we are going to fight for it.


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Wigan Athletic’s astonishing 1-0 FA Cup fifth-round win over Premier League leaders Manchester City, secured with minimal possession on Monday night, is being celebrated up and down the land.
The huge underdogs’ victory, and subsequent pitch invasion that saw Sergio Agüero clash with a fan, has kept the magic of the cup alive in many a football fan’s heart.
These are the best of the jokes after Wigan 1-0 Man City:
"What's the Wigan score?" pic.twitter.com/vA6SI5ucYU
— Ellis Platten – AwayDays (@ellis_platten) February 19, 2018
This would be the biggest cup shock since Wigan beat Manchester City.
— LFC Fans Corner (@LFCFansCorner) February 19, 2018
Net worth of City's squad vs Wigan's?……… Asking for a mate.
— Scotty Tridge (@TridgeTV) February 19, 2018
De Bruyne: £68m
Losing to League One Wigan: Pretty f*cking funny
— Paddy Power (@paddypower) February 19, 2018
Wigan Athletic 1-0 Manchester City pic.twitter.com/8YOVs3zBOx
— bet365 (@bet365) February 19, 2018
On a positive for Manchester City, Wigan aren't in the Champions League.
— Coral (@Coral) February 19, 2018
That Wigan fan deffo told Augero the faulklands are ours
— Coxy (@Joshcox_wwfc) February 19, 2018
Wigan playing Oasis at FT https://t.co/IYCxwAw4Pb
— Benj (@Beniesta_) February 19, 2018
Guardiola: "Congratulations to Wigan for qualification, they had one shot on target." pic.twitter.com/J5mUhdg2CL
— Footy Accumulators (@FootyAccums) February 19, 2018
It's Wigan Shathletic
— ᴛᴏᴍ49 (@TomGooner49) February 19, 2018
Wigan v Rochdale on Saturday, worst game of Football you'll very watch. 22 players still hammered.
— GeorgeWeahsCousin (@WeahsCousin) February 19, 2018
Going by Twitter, it would appear that the best thing that's happened to basically all our rivals this year is us losing against Wigan.
— Steven (@StevenMcinerney) February 19, 2018
One reason why they won't: Wigan pic.twitter.com/5oMtciYfyl
— Wicky (@Wicknes007) February 19, 2018
Everyone going on about Guardiola transforming his players’ diets but it turns out they’re all Latics intolerant
— Tom Victor (@tomvictor) February 19, 2018


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Valencia on the Lake is a secluded community with new single-family homes in Little Elm.. Nestled on the banks of Lake Lewisville, residents enjoy beautiful views and walking paths along the lake. Amenity center, pool and splash pool. Little Elm ISD with future onsite elementary. Quiet peninsula living. 50' tree-lined lake homesites included.
Subdivision: Valencia on the Lake
Limited Opportunities Remain - Schedule your tour today! Located on the shores of Lake Lewisville, Valencia on the Lake is the latest lakeshore development planned on 448 acres in Little Elm that will offer affordable lakeshore living.. The community will feature some upscale town home living and...
MLS ID 1564253
2000 Miramar Dr Little Elm, TX

domain: geography


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Please Note: The Optimist Legends Boys and Girls Soap Box Derby that usually takes place during Springtime in Paris has been cancelled for 2018
Along Broadway Street East in Paris (old Station Hill), parents and their children will line the hill to watch their creations race off our ramp and down Broadway Street Hill to the finish line.
The race is a double knock out with all racers guaranteed a minimum of 2 races. All participants will receive an Optimist Legends Soapbox Derby T shirt and a free pop and burger courtesy of the Paris Lions Club after the race in front of the Band shell at Lions Park. The top 4 racers in each division will each receive a trophy and a medal, and there will be a trophy for the soap box racer that demonstrates the best appearance and originality.
Please note, the Optimist Legends Boys and Girls Soap Box Derby will not run if weather conditions are not favourable.
To register, click on the Registration tab above.
Be sure to review the Race Rules (see Rules tab).
We appreciate the assistance we receive for this event from Paris Fire and Rescue
and the very generous support of our local Sponsors.
Springtime in Paris is June 2 and 3, 2018
in Paris, Ontario
Click here to for more information

domain: sports


Single Hose vs Dual Hose Portable Air Conditioner - AirNeeds
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Compare Cch Portable Air Conditioner Dual Hose prices at Airconditioneri.com. CCH at a discount.Wish that you can find out the best one which can adapt your need and.Updated May 23, 2018. A dual-hose portable air conditioner usually cools a room faster, using less energy overall,.Here are some differences between single hose vs dual hose portable air conditioner.Portable air conditioning units will either have one exhaust.
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Indoor Portable Air Conditioner Efficiency ImprovementOption The Climax VS12 Climax offers a 12,000 BTU DC Inverter dual hose portable AC that delivers its full rated capacity.
Our team of experts has selected the best portable air conditioners out of.Understand the difference between single hose and dual hose portable air conditioning units.ECO-FRIENDLY 14,000 BTU PORTABLE AIR CONDITIONER. Air intake hose 5.For the single hose portable air conditioner to be effective,.


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The Northeast & Canada
July | 2015
July 1, 2015 — Planning out my trip up north to the Canadian border has been a bit more challenging than I expected. I've been told by many: "What's there to see in the Canadian border, but pine trees and wild animals?"
When I think of border life in upper New England, and specifically in Maine, I think of Acadian or French-speaking people.
Maine is one of the few states where more than half the people reported in the 2000 U.S. Census that they spoke French at home. Available information shows that the proportion of the population who speak French in Northern Maine is much higher than in the rest of Maine. The French language is in everyday use from Fort Kent to Van Buren, Maine. It is heard on the street, in restaurants and stores, at public meetings, at work places, and in homes. Catholic masses are regularly delivered in French in many of the parishes.
My next stop to learn about U.S. border life will be Canada. Based on what I've read and seen in my visits to Maine in recent years, I have a feeling I will be pleasantly surprised as I discover and learn more about its border life.
I leave on July 15 and my destination is the international border crossing in Calais, Maine and into New Brunswick, Canada.


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II Chronicles 7-12
7[1-5] Now when Solomon had finished praying, the fire came down from heaven, and burnt up the burnt offering and the sacrifices; and the brightness of Yahweh’s glory filled the house. The preachers couldn’t go into the Place of Worship of Yahweh, because the brightness of Yahweh filled God’s house. All the people of Israel looked on when the fire came down, and the glory of Yahweh was on the house; and they bowed themselves with their faces to the ground on the pavement, and worshiped, and gave thanks to Yahweh, saying, God is good whose loving kindness lasts forever. Then the ruler and all the people offered sacrifices before Yahweh.
[5-8] King Solomon offered a sacrifice of 22,000 cows, and 120,000 sheep. So the ruler and all the people dedicated the house of God. The preachers stood, according to their offices; the Levites also with instruments of music of Yahweh, which David the ruler had made to give thanks to Yahweh, whose loving kindness lasts forever, when David praised God by their ministry; and the preachers sounded horns before them; and all Israel stood. Besides Solomon made the middle of the court holy that was before the Place of Worship of Yahweh because there he offered the burnt offerings, and the fat of the peace offerings, because the bronze altar, which Solomon had made wasn’t able to hold the burnt offering, the meal offering, and the fat. So Solomon held the celebration at that time seven days, and all Israel with him, a very great assembly, from the entrance of Hamath to the River of Egypt.
[9-11] On the 8th day they held a solemn assembly because they kept the dedication of the altar seven days, and the celebration seven days. On the 23rd day of the 7th month (Tishri Sept.-Oct.) he sent the people away to their tents, joyful and glad hearted for the goodness that Yahweh had shown to David and Solomon, and to Israel God’s people. So Solomon finished the Place of Worship of Yahweh, and the ruler’s house; and whatever came into Solomon’s heart to make in the Place of Worship of Yahweh, and in his own house, he finished well.
[12-16] Then Yahweh appeared to Solomon by night, saying to him, “I’ve heard your prayer, and have chosen this place for myself for a house of sacrifice. If I shut up the sky so that there’s no rain, or if I tell the locust to destroy the land, or if I send disease among My people; If My people, who are called by My Name, will humble themselves, and pray, and turn to Me, and turn from their sinful ways; then I’ll hear from heaven, forgive their sin, and heal their land. Now my eyes will see and my ears will hear the prayer that is made in this place. For now I’ve chosen and made this house holy, that My Name may be there forever; and My eyes and My heart will be there continually.
[17-22] As for you, if you’ll walk before me as David your father walked, and do according to what I’ve told you, and will keep My laws and My rules; then I’ll set up the throne of your land, as I promised David your father, saying, There won’t fail you someone to be ruler in Israel. But if you turn away from My laws and My words which I’ve set before you, and go and serve false gods, and worship them; then I’ll pluck the people up by the roots out of My land which I’ve given them; and this house, which I’ve made holy for My Name I’ll put out of My sight, and I’ll make it a saying and a mockery among all peoples. This house, which is so high, everyone who passes by it will be shocked, and say, ‘Why has Yahweh done this to this land and this house?’ And they’ll answer, ‘Because they left Yahweh, the God of their ancestors, who brought them out of the land of Egypt, and took hold of other gods, worshiping them and serving them; so God has brought all this evil on them.’”
8[1-6] At the end of 20 years, in which Solomon had built the Place of Worship of Yahweh, and his own house, the cities which Huram had given to Solomon, Solomon built them, and made the people of Israel to live there. Solomon went to Hamath Zobah, and was strong against it. He built Tadmor in the countryside, and all the storage cities, which he built in Hamath. He also built Beth Horon, the upper and the lower, protected cities, with walls, gates, and bars; and Baalath, and all the storage cities that Solomon had, and all the cities for his war vehicles, and the cities for his horse riders, and whatever Solomon wanted to build for his pleasure in Jerusalem, and in Lebanon, and in all the land of his dominion.
[7-11] As for all the people who were left of the Hittites, Amorites, Perizzites, Hivites, and Jebusites, who weren’t of Israel; of their children who were left after them in the land, whom the people of Israel didn’t kill, Solomon made them workers and taxed them to today. But of the people of Israel, Solomon didn’t make any workers for his work; but they were soldiers, and leader of his captains, and rulers of his war vehicles and of his horse riders. These were the head officers of Solomon, 250 who ruled over the people. Solomon brought the daughter of the Ruler of Egypt out of the city of David to the house that he had built for her because he said, “My wife won’t live in the house of David ruler of Israel, because the places are holy, where the Chest of Yahweh has come.”
[12 -15] Then Solomon offered burnt offerings to Yahweh on the altar of Yahweh, which he had built before the porch, as the duty of every day required, offering according to the word of Moses, on the Seventh Days, on the new moons, and on the set celebrations, three times in the year, even in the celebration of bread made without yeast, and in the celebration of weeks, and in the Celebration of Booths. He set, according to the rule of David his father, the divisions of the preachers to their service, and the Levites to their offices, to praise, and to minister before the preachers, as the duty of every day required; the doorkeepers also by their divisions at every gate as David the follower of God had told him. They didn’t change the word of the ruler to the preachers and Levites in any way, or change anything about the treasures.
[16-18] Now all the work of Solomon was done from the day of the foundation of the Place of Worship of Yahweh until it was finished. So the Place of Worship of Yahweh was finished. Then Solomon went to Ezion Geber, and to Eloth, on the seashore in the land of Edom (Arab nations). Huram sent him by the hands of his workers ships, and workers who had knowledge of the sea; and they came with the workers of Solomon to Ophir, and picked up from there 33,750 lbs of gold, and brought them to ruler Solomon.
9[1-4] When the Ruler of Sheba heard of the fame of Solomon, she came to prove Solomon with hard questions at Jerusalem, with a very great train of camels that had spices, and much gold, and precious stones; and when she had come to Solomon, she talked with him of what was in her heart. Solomon answered all her questions; and Solomon didn’t keep any secrets from her. When the Ruler of Sheba had seen the wisdom of Solomon, and the house that he had built, the food on the table, the seating of the servants, the attendance of his ministers and their clothing, his cup bearers and their clothing also, and the grand steps by which he went up to the Place of Worship of Yahweh; there was no more spirit in her.
[5-9] She said to the ruler, “It was true what I heard in my own land about your acts, and your wisdom. But I didn’t believe their words, until I came, and my eyes had seen it; and see, the half of the greatness of your wisdom wasn’t told me; you’re more famous than what I had heard. Happy are your people and Your workers, who stand continually before you, and hear your wisdom. Blessed be Yahweh, your God, who was pleased to set you on the throne, to be ruler for Yahweh, your God; because your God loved Israel, to set them up forever, so God made you ruler over them, to do justice and goodness.” She gave the ruler 9,000 lbs of gold, and many spices and precious stones; nor was there any spice like the ruler of Sheba gave to the ruler Solomon.
[10-12] The workers also of Huram and of Solomon, who brought the gold from Ophir, also brought algum trees, and precious stones. The ruler made of the algum trees porches for the Place of Worship of Yahweh, and for the ruler’s house, and harps and lyres for the singers; and there were none seen like this ever before in the land of Judah. King Solomon gave to the ruler of Sheba everything she wanted, whatever she asked for, besides what she had brought the ruler. So she went back to her own land, she and her workers.
[13-19] Now the weight of gold that came to Solomon in one year was 49, 950 lbs (666 talents) of gold, besides what the traders and sales peoples brought; and all the rulers of Arabia and the governors of the country brought gold and silver to Solomon. King Solomon made 200 shields of beaten gold with 600 gold coins going into each shield. He also made 300 smaller shields of beaten gold with 300 gold coins going into each one; and the ruler put them in the house of the forest of Lebanon. Besides, the ruler made a great throne of ivory, and overlaid it with pure gold. And there were six steps to the throne, with a footstool of gold, which were fastened to the throne, and armrests on either side of the seat, and two lions standing beside them. There were 12 lions that stood on each side of the six steps; there wasn’t anything like it made in any country before.
[20-24] All ruler Solomon’s drinking cups were of gold, and all the dishes of the house of the forest of Lebanon were of pure gold; silver wasn’t of any value in the days of Solomon. For the ruler had ships that went to Tarshish with the workers of Huram; the ships of Tarshish came once every three years, bringing gold, silver, ivory, apes, and peacocks. So ruler Solomon was greater than all the rulers of the earth in riches and wisdom. All the rulers of the earth went to Solomon to hear his wisdom, which God had put in his heart. They brought their tax money, pots of silver and gold, clothing, armor, spices, horses, and mules, a set rate year by year.
[25-31] Solomon had 4,000 stalls of horses and war vehicles, and 12,000 riders that he had in the war vehicle cities and with the ruler at Jerusalem. He ruled over all the rulers from the Euphrates River to the land of the Philistines, and to the border of Egypt. The ruler made silver as common in Jerusalem as stones and cedars as common as the sycamore trees that are in the lowland. They brought horses for Solomon out of Egypt, and out of all lands. Now the rest of the acts of Solomon, from the first to the last, are written in The History of Nathan the Preacher, and in The Preaching of Ahijah the Shilonite, and in The Visions of Iddo the Preacher about Jeroboam of Nebat. Solomon ruled in Jerusalem over all Israel for 40 years. Solomon died and was buried with his ancestors and was buried in the city of David his father; and Rehoboam his son ruled in his place.
10[1-5 Rehoboam went to Shechem because all Israel had come to Shechem to make him ruler. When Jeroboam of Nebat heard it, (for he was in Egypt, where he had run away from the ruler Solomon), he came back from Egypt. They sent and called him; and Jeroboam and all Israel came, and they said to Rehoboam, “Your father made our service very hard; So now make that very hard service of your father, and the hard jobs he put on us, lighter, and we’ll serve you. So he said to them, Come back to me after three days” and the people left.
[6-11] King Rehoboam counseled with the old men, who had stood before Solomon his father while he still lived, saying, “What answer can you give me to say to these people?” They said to him, “If you’re kind to these people, and do what they want, and speak kindly to them, then they’ll be your workers forever. But he didn’t take the advice of the old men which they had given him, and counseled with the young men who had grown up with him, “Who stood before him.” He said to them, “What answer can you give me, that we may say to these people, who have said to me, ‘Make the service that your father put on us lighter?’” The young men who had grown up with him said to him, “You should tell the people who said to you, ‘Your father made our service hard, but make it lighter to us;’ you should say to them, ‘My little finger is thicker than my father’s penis. Now while my father put on you a hard service, I’ll add more to your service; my father punished you with whips, but I’ll punish you with scorpions.’”
[12-19] So Jeroboam and all the people came to Rehoboam the third day, as the ruler had said, “Come back to me the third day.” The ruler answered them roughly; and he refused the advice of the old men, saying to them what the young men had said, “My father made your service hard, but I’ll add to it; my father punished you with whips, but I’ll punish you with scorpions.” So the ruler didn’t listen to the people because it was brought about of God that Yahweh would prove the word which was said by Ahijah the Shilonite to Jeroboam of Nebat. When all Israel saw that the ruler didn’t listen to them, the people answered him, saying, “What part do we have in David? nor do we have any part in the son of Jesse; everyone to your tents, Israel; now see to your own house, David.” So all Israel went to their tents. But as for the people of Israel who lived in the cities of Judah, Rehoboam ruled over them. Then ruler Rehoboam sent Hadoram who was over their workers; and the people of Israel stoned him to death with stones. Ruler Rehoboam quickly got into his war vehicle, and ran to Jerusalem. So Israel rebelled against the house of David to today.
11[1 -4] When Rehoboam had come to Jerusalem, he gathered the people of Judah and Benjamin, 180,000 of the best soldiers, who were warriors, to fight against Israel, to take the country back for Rehoboam. But the word of Yahweh came to Shemaiah, the follower of God, saying, “Speak to Rehoboam, son of Solomon, ruler of Judah, and to all Israel in Judah and Benjamin, saying, Yahweh says, You won’t go up, nor fight against your family members; everyone go back home because this thing is of Me. So they listened to the words of Yahweh, and didn’t fight against Jeroboam.
[5-13] Rehoboam lived in Jerusalem, and built cities for defense in Judah. He built Bethlehem, Etam, Tekoa, Beth Zur, Soco, Adullam, Gath, Mareshah, Ziph, Adoraim, Lachish, Azekah, Zorah, Aijalon, and Hebron, which are in Judah and in Benjamin, all protected cities. He protected the strongholds, and put captains in them, and stores of food, and oil and wine. He put shields and spears in every city, and made them very strong. Judah and Benjamin belonged to him. The preachers and the Levites who were in all Israel came to him out of all their border.
[14-17] The Levites left their borders and their homes, and came to Judah and Jerusalem because Jeroboam and his sons threw them out so that they couldn’t do the preacher’s office for Yahweh; and he set up his own preachers for the places of false worship, and for the false gods, and the golden calves which he had made. After them, out of all the family groups of Israel, those that set their hearts to worship Yahweh, the God of Israel, came to Jerusalem to sacrifice to Yahweh, the God of their ancestors. So they strengthened the land of Judah, and made Rehoboam of Solomon strong for three years because they walked three years in the way of David and Solomon.
[18 -23] Rehoboam took a wife, Mahalath, the daughter of Jerimoth, son of David and Abihail, the daughter of Eliab, son of Jesse; and she had Jeush, Shemariah, and Zaham. After her he took Maacah, the daughter of Absalom; and she had Abijah, Attai, Ziza, and Shelomith. Rehoboam loved Maacah, the daughter of Absalom, more than all his other wives and his mistresses; (for he took 18 wives, and 60 mistresss, and had 28 sons and 60 daughters.) Rehoboam made Abijah, of Maacah, to be leader, even the head of his family because he thought to make him ruler. He dealt wisely, and put all his sons throughout all the lands of Judah and Benjamin, in every protected city; and he gave them much food. He searched for them many wives.
12[1-4] When Rehoboam had set up his country and he was strong, he stopped following the law of Yahweh, and all Israel with him. In the 5th year of ruler Rehoboam, Shishak, ruler of Egypt, came up against Jerusalem because they had sinned against Yahweh, with 1200 war vehicles, 60,000 riders, and so many people they couldn’t be counted, who came with him out of Egypt; the Lubim, the Sukkiim, and the Ethiopians. He took the protected cities which belonged to Judah, and came to Jerusalem.
[5-8] Now Shemaiah, the preacher, came to Rehoboam, and to the leaders of Judah, who were gathered together to Jerusalem because of Shishak, saying to them, “Yahweh says, You’ve left Me, so I have also left you in the hand of Shishak.” Then the leaders of Israel and the ruler humbled themselves and said, “Yahweh is good.” When Yahweh saw that they humbled themselves, the word of Yahweh came to Shemaiah, saying, “They’ve humbled themselves, so I won’t destroy them; but I’ll give them some victory, and My anger won’t be poured out on Jerusalem by the hand of Shishak. But they’ll be his workers, that they may know the difference between My service, and the service of the nations.
[9-12] So Shishak ruler of Egypt came up against Jerusalem, and took away all the treasures of the Place of Worship of Yahweh, and all the treasures of the ruler’s house; he also took away the shields of gold which Solomon had made. Ruler Rehoboam made in their place shields of brass, and put them in the hands of the leaders of the guard, who kept the door of the ruler’s house. As often as the ruler went into the Place of Worship of Yahweh, the guard came and had them, and brought them back into the guard room. When he humbled himself, the anger of Yahweh turned from him, so as not to destroy him altogether; and everthing went well in Judah.
[13-16] So Ruler Rehoboam strengthened himself in Jerusalem, and ruled. Rehoboam was 41 years old when he began to rule, and he ruled 17 years in Jerusalem, the city which Yahweh had chosen out of all the family groups of Israel, where God’s Name was; and his mother’s name was Naamah the Ammonitess. He did what was evil, because he didn’t set his heart to worship Yahweh Now the acts of Rehoboam, first and last, are written in the histories of Shemaiah, the preacher, and of Iddo, the preacher, which lists the genealogies. There were wars between Rehoboam and Jeroboam continually. Rehoboam died, and was buried in the city of David; and Abijah his son ruled in his place.


Quantum Tunneling and Wave Packets 1.12Free
Watch quantum "particles" tunnel through barriers. Explore the properties of the wave functions that describe these particles.
Visualize wave functions for constant, step, and barrier potentials.
Visualize both plane wave and wave packet solutions to the Schrodinger equation and recognize how they relate to each other.
Interpret and distinguish the real part, imaginary part, and absolute value of the wave function, as well as the probability density.


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denada balcony design, 2018-02-16 04:48:02. Transforming your balcony into useful lively space is not a very difficult task. If your balcony is connected to your living room then it is very important that you design it perfectly so that it can be used as an extension of your living room.
caelyine balcony design, 2018-02-15 17:12:22. There are only few people who have a balcony leading off a bedroom at home and from those who are flowers and plants lover, this small place is the only green space from them. Balcony is usually a small area that restricts the choice of planting and arrangement of decorative species. Bedroom balcony is in fact an aromatic place of luxury and pleasure, where one can enjoy his or her time amidst of scented and colorful plants with a sense of natural scenery.
abigael balcony design, 2018-02-15 17:02:17. There are countless features to choose from but each addition must complement the existing decor on the primary building structure. If you have copper trim and downspouts around the home, consider adding copper lighting fixtures and an enclosure or railing with copper accents. You do not want your designs to clash so that the home looks ill put together overall.
denada balcony design, 2018-02-15 17:01:01. Another thing that you can do is to implement a multi-layer lighting design that is sufficiently adaptable for creating the right ambiance for different uses and events. Shop around for outdoor wall sconces, miniature lampposts, task lights and overhead lighting. Versatile lighting options can create the same level of aesthetics that you enjoy with your lighting on the inside of the home.
denada balcony design, 2018-02-15 17:12:48. When properly designed, balcony seating has some benefits worth considering. Balconies can solve the problem of future expansion as the congregation grows and can enable a church with limited land to expand "up" rather than "out". In fan-shaped sanctuaries a balcony can increase the seating by almost 50%. A future balcony should be master-planned from the start with the major structure completed during the sanctuary construction. A removable wall can temporarily hide this unfinished space.
bernard balcony design, 2018-02-15 17:10:57. Another thing that you can do is to implement a multi-layer lighting design that is sufficiently adaptable for creating the right ambiance for different uses and events. Shop around for outdoor wall sconces, miniature lampposts, task lights and overhead lighting. Versatile lighting options can create the same level of aesthetics that you enjoy with your lighting on the inside of the home.
bernard balcony design, 2018-02-15 17:01:23. A nachomarin balcony is essentially a false balcony attached to the side of a house so that it surrounds French or double doors. nachomarin balconies are often still made to fit the traditional model from the Shakespeare play: a short, narrow rectangle surrounded by stone balustrade that is supported by plinths and opens almost immediately into the adjoining room through glass doors. They are becoming increasingly popular, as more and more people convert existing windows to allow for increased light and ventilation. Obviously the doors have to open inwards to make the most of a feature like this. By changing windows to double doors or French doors, the balcony fixes to the external masonry to prevent anyone from falling out. nachomarin balconies are more than just a safety feature however, with many homeowners installing them as nothing more than an external design feature.
denada balcony design, 2018-02-15 19:42:25. Always be mindful of the need for a suitable railing. This is essential for compliance with local building codes and for limiting homeowner liability. Fortunately, these structures can be as aesthetically pleasing as they are safe and supportive. You can choose from steel or stainless steel railing or decorative glass balustrades. The best options will both enhance user safety and create a visually appealing and mood-specific ambiance.
Any content, trademark/s, or other material that might be found on this site that is not this site property remains the copyright of its respective owner/s. In no way does oxygenconcentratordepot claim ownership or responsibility for such items, and you should seek legal consent for any use of such materials from its owner.


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Whether it’s fueling up before hitting the gym or taking a mid-day snack break to avoid the 2 o’clock lull, high-protein snacks are the tastiest way to keep on going. Protein snacks are the perfect way to fill up just enough, and give us longer-lasting energy than the usual, carb-heavy options. Here are 31 of our favorite protein-packed snacks — one for every day of the month! We promise you won’t get sick of any of these choices.
1. Cottage-Style Fruit: Top ½ cup cottage cheese with ½ cup of your favourite fruit. Why not try some super foods?Bananas, mixed berries, and melon are some favourites!
2. Beef or Turkey Jerky: Be careful to avoid sodium- and sugar-filled brands, but low-sodium, natural, or lightly-flavoured options are a great super foods. And this chewy snack is super-portable and keeps fresh for months when packed properly. A one-ounce serving (the size of most single-serve packs) contains about 9 grams of protein!
3. Mixed Nuts or Trail Mix: This is a favourite for the office. Mixed nuts are an easy way to get a delicious dose of protein in a convenient, shelf-stable package. Try a mixed bunch for variety and a combo with dried fruit for some added sweetness. The best bang for your protein buck? Almonds and Pistachio are high up there in protein while comparably lower in saturated fat than their nutty peers.
4. Pumpkin Seeds: Those orange pumpkins are not just for Halloween. The pumpkin insides, scooped out to make room for spooky faces, can actually make a healthy little snack once they’re washed, dried, and nicely roasted! Just ½ cup of pumpkin seeds has about 14 grams of protein — the perfect pre-workout!
5. Hard-Boiled Egg: Inexpensive and loaded with nutrients, eggs are one of the best ways to get a healthy dose of protein. Try hard boiling and pre-peeling a dozen at the start of the week and throw one in a small Tupperware container each day for an easy on-the-go snack. (Feeling extra famished? Slice the egg and place it on a piece of whole-wheat bread.)
6. Deli Roll up: Top 2 slices of low-sodium deli meat (turkey, chicken, or roast beef work great!) with 1 slice of low fat cheese and a shake of pepper. Add a slice of tomato or some lettuce for extra veggie points!
Photo by Caitlin Covington
7. Nut Butter Boat: Any vehicle for nut butter (almond, peanut, or cashew, perhaps?) is perfection in our book. Try loading a few celery sticks with 1 tablespoon of any nut butter topped with a few whole almonds or raisins (oh yeah, we went there). If you’re not a fan of celery, try scooping out the middle of an apple and fill it with a nut buttery surprise!
8. Mini Bean-and-Cheese Quesadilla: It might take an extra minute to prep, but combining these two high-protein treats is worth it! Fold ½ cup black beans, 1 tablespoon salsa, and 1 slice cheddar cheese in a small soft tortilla. Cook in a dry non-stick pan until cheese is melted and tortilla is lightly browned. Wrap in foil and stick in a plastic bag for easy transport.
9. Shake It Up: The combinations are endless with protein shakes. And one scoop can go a long way! Our favourites? The “Protein Creamsicle” — 1 scoop vanilla whey protein powder, 1 cup orange juice, and 1 cup ice blended until smooth — (thanks JCDFitness!), and the “Star-buffs Shake” — 1 cup iced coffee (with ice) and 1 scoop chocolate whey protein, blended — a caffeine-filled creation from Greatist’s fitness editor, Jordan Shakeshaft.
10. KIND Bar: We’re not huge supporters of pre-packaged bars, smoothies, and the like, but we make an exception for KIND bars. Their classic varieties are a great source of protein from the all-nut base (coming in at around 5 grams per bar), but for an even higher dose of the good stuff, try Kind Plus varieties with added protein. (An office favoUrite is Peanut Butter Dark Chocolate + Protein — one bar has 7 grams!)
11. Easy Oatmeal Raisin Cookie: Flash back to elementary school snack time with this sweet (but still healthy!) treat. In a microwave-safe bowl (or mug), mix ¼ cup oats, 1 teaspoon brown sugar, 1 tablespoon flour (of your choice), 1 egg white, ¼ teaspoon vanilla extract, 1/4 teaspoon baking powder, 1 teaspoon cinnamon, and 1 tablespoon raisins. Flatten mixture into bottom of bowl and microwave on high for 45 seconds. Cool, pop it out of the bowl, and enjoy!
12. Tofu Sticks: This soy-bean-based protein bomb isn’t just for stir-fry and Asian take-out menus! When sliced into sticks, firm (and smoked!) tofu can make a great snack food, especially if it’s served with a side of home-made tomato or teriyaki dipping sauce — just don’t overdo it!
Photo by Lisa Goulet
13. Chunky Monkey Shake: It’s time to get funky, monkey! Blend 1 medium banana, 1 tablespoon of peanut butter, and 1 cup of low-fat chocolate milk with 1 cup of ice for a protein-packed pick-me-up.
14. Edamame Poppers: The only thing more fun than how much protein you can get from a serving of edamame is getting to eat these little beans out of their bright green pods! One cup of the pods offers about 17 grams of protein. Buy them fresh and steam for about 6 minutes, or use the pre-cooked frozen variety and briefly microwave to defrost (about 2 minutes) before chowing down.
15. Hummus Dippers: How’s this for an unconventional use of a travel coffee mug: Put 2 tablespoons of a favourite hummus in the bottom of the container. Stick a handful of vegetable sticks (carrots, celery, and snow peas are a great mix!) vertically in the hummus, screw on the top, and throw in a purse or gym bag for an easy, on-the-go, super-healthy snack.
16. Milk Smoothie: Cow’s milk does have nutritional benefits (calcium and vitamin A, to name a few). Try blending 1 cup of your favourite flavour of soy milk (vanilla and chocolate are favourites) with 1 cup of frozen blueberries or raspberries (for added fibre and antioxidants).
17. Portable Cheese Platter: Everyone wants to feel classy every once in a while, right? Make yourself a mini cheese plate with 2 slices of cheese, two whole-grain crackers, and a few roasted almonds.
18. Banana Nutter: Few pairings are more comforting than a classic peanut butter and banana combo. Top a rice cake (brown rice for extra fibre points!) with 2 tablespoons of your favourite nut butter and half a banana, sliced. Sprinkle with cinnamon for some extra healthy benefits!
Photo by Caitlin Covington

domain: food


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Local dementia care specialists
More than half of UK adults know someone who has been diagnosed with dementia
Right Care (Lancashire) Ltd will ensure that you get care at a high standard of care that respects and protects your right to continue making your own decisions as long as you are able.
Dementia can affect your ability to manage the simplest of day-to-day tasks like remembering to eat, drink or even take regular medications - that's where our care workers will step in ensuring you have timely reminders and help with any tasks that may be becoming a struggle.
We are passionate about tailoring our dementia care for every user of our services, we like to understand them and what they enjoy and get to know them on a personal level to ensure all their needs are met by people who truly get them.
Give us a call today to arrange dementia care anywhere in Burnley and Pendle.
Right Care (Lancashire) Ltd are committed to the four principles of the Dementia Pledge:
Know the person who is living with dementia
Provide quality care for a quality life
Everybody has a leadership role
Provide value-focussed care
Our dedicated dementia carers would be happy to discuss your needs, contact us today.
Call us on 01282 424240

domain: medical


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Celebrate Without Drama
9:14am 1st June 2012
People in Weymouth and Portland are being encouraged to act responsibly during this summer's main events.
Dorset County Council has launched an awareness campaign called "Celebrate Without Drama", focusing on safety and not binge drinking during the Jubilee, Euro 2012 and Olympics.
A new website's been made where you can access all the latest safety information from the local NHS and Pub Watch group.
A radio and poster campaign will also run throughout the summer to raise awareness.
Councillor Ray Nottage, chair of Dorset Community Safety Partnership, said:
"We've got a great summer of celebration ahead of us which we hope will be enjoyed sensibly by all. Unfortunately, it's all too easy for things to get out of hand when people have had too much to drink. This campaign will give people all the information they need about enjoying the summer events without it ending in drama".
You can take a look at the website here.


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The latest addition to my shelf this week, should definitely be an interesting read. ‘Playing Mrs. Kingston’, is author Tony Lee Moral’s debut fiction book, although by no means his first published work. The titles of his three previously published non-fiction books, offer a big clue as to the influence which has been fundamental in shaping and inspiring his fiction writing.
Hitchcock for me is the consummate filmmaker and the one to be studied. He has inspired more directors, screenwriters and producers than any other film-maker in history, which is why he has had more books written about him than any other director. He understood how to use the camera and tell a story visually better than anybody, and had an innate understanding of camera logic.
As a Hitchcock fan myself, I shall be looking forward to having Tony visit very soon, with a guest post about the great man.
‘PLAYING MRS. KINGSTON’
It’s the ‘50s in New York City, and Catriona Benedict has big dreams, but when her first promising gig as an actress is a flop, she has to figure out some other way to make a living in the big city.
Enter Miles Kingston, a rich and influential playboy who, for reasons of his own, asks Catriona to take on the biggest role of her life…as his wife. Despite her boyfriend’s misgivings about the arrangement, Catriona knows that this could easily be the most lucrative acting job she’s ever had. All she has to do is keep up the act for a few weeks, and she’ll walk away with thousands.
When tragedy strikes, the whole arrangement threatens to strangle Catriona. She quickly realizes that living with the Kingston family is a much more delicate and dangerous affair than she ever could have guessed.
And if she isn’t convincing in the role of Mrs. Kingston, much more than just her acting career will be at stake.
TONY LEE MORAL
Tony was born in the historical town of Hastings, Sussex, England. From an early age he looked to the horizon, with a keen quest for knowledge and an avid interest in writing.
Following an early publishing success, with the formation of his own software company for the booming home computer market, Tony moved on to the internationally renowned BBC Natural History Unit, where he spent many formative years filming in remote places around the world, everywhere from the Himalayas to the Amazonian rainforest.
In 1999, Tony moved to California to work on the award winning ‘The Shape of Life’ series, to write his books on Alfred Hitchcock, and to continue making his diverse and eclectic documentaries, ranging from biographies to current affairs, in the course of which he has interviewed a veritable A-Z of celebrities from the arts and sciences.
As well as making films around the world, Tony has launched his own production company Sabana Films, dedicated to making bespoke documentaries.
Check out all Tony’s latest news on his website.
Follow Tony on Twitter.
Like Tony’s fan page on Facebook.
…Mailbox Monday is a gathering place for readers to share the books that came into their house during the last week. Be warned that Mailbox Monday can lead to envy toppling TBR piles and humongous wish lists.
Mailbox Monday now has a permanent home, where links may be added each week. So why not stop by, leave a link to your own Mailbox Monday post, oh! and don’t forget to leave a comment for our three new joint administrators, after all, we all like to receive them … ‘Mailbox Monday’
Leslie of ‘Under My Apple Tree’
Serena of ‘Savvy Verse & Wit’
Vicki of ‘I’d Rather Be At The Beach’
This is a great way to plan out your reading week and see what others are currently reading as well… you never know where that next “must read” book will come from!


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Upvoming is a free series of events with “Docs” (MDs, dentists, veterinarians, pharmacists) in the castle of Sumiswald which should be transmitted by livestream.
- recitals with MusicDocs
- readings with WriterDocs
- art exhibitions with ArtDocs
Have a look on the talents website https://talents.doctorsdome.center and get impressions what you can await.
and this is flowing into www.DoctorsDome.tv as a further concept.


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- Is Rosemary Kennedy alive?
- Which Kennedy died today?
- How much money did Jackie Kennedy get from Onassis death?
- Why did Joseph Kennedy lobotomy his daughter?
- What happened Kennedy family?
- What happens after a lobotomy?
- Did Rosemary Kennedy have a baby?
- Are lobotomies still used?
- How much money did Jackie Onassis inherit from Aristotle?
- Are there any Kennedy siblings left?
- Who was JFK’s sister?
- Who is Joe Kennedy’s father?
- How did the Kennedy family get rich?
- Was John F Kennedy the oldest child?
- Did a Kennedy die?
Is Rosemary Kennedy alive?
Deceased (1918–2005)Rosemary Kennedy/Living or Deceased.
Which Kennedy died today?
Saoirse Kennedy Hill: A granddaughter of Robert F. Kennedy, Saorise Kennedy died of an accidental overdose Aug. 1, 2019, at the Kennedy compound in Hyannis Port, Massachusetts, The New York Times reported. She was 22.
How much money did Jackie Kennedy get from Onassis death?
Jackie had already known Maurice Templesman for nearly two decades by the time she settled in New York in 1975, but it was only then that they grew close. Tempelsman stepped in to help Jackie manage her finances and the $26 million inheritance left to her by Onassis.
Why did Joseph Kennedy lobotomy his daughter?
When Rosemary was 23 years of age, doctors told her father that a form of psychosurgery known as a lobotomy would help calm her mood swings and stop her occasional violent outbursts.
What happened Kennedy family?
died in a plane crash (along with his wife Carolyn and sister-in-law Lauren) off the coast of Martha’s Vineyard in 1999; Kara Kennedy and Christopher Kennedy Lawford died of heart attacks, in 2011 and 2018 respectively; and Saoirse Kennedy Hill died of a drug overdose in 2019.
What happens after a lobotomy?
Freeman believed that cutting certain nerves in the brain could eliminate excess emotion and stabilize a personality. Indeed, many people who received the transorbital lobotomy seemed to lose their ability to feel intense emotions, appearing childlike and less prone to worry.
Did Rosemary Kennedy have a baby?
Good arrives. When the doctor finally arrives, he delivers a baby girl and pronounces her healthy.” However, Rosemary was not healthy, and the complications of her birth would cause serious repercussions for the rest of her life. Named after her mother, Rosemary was the Kennedy’s third child and first daughter.
Are lobotomies still used?
Lobotomy is rarely, if ever, performed today, and if it is, “it’s a much more elegant procedure,” Lerner said. “You’re not going in with an ice pick and monkeying around.” The removal of specific brain areas (psychosurgery) is only used to treat patients for whom all other treatments have failed.
How much money did Jackie Onassis inherit from Aristotle?
Onassis, the so-called Golden Greek, burst onto the international scene when he married the widowed Jacqueline Kennedy. Upon his death, Aristotle left his wife $250,000 and bequeathed $500 million to his only surviving child, Christina Onassis.
Are there any Kennedy siblings left?
They adopted two daughters, Amanda Smith and Kym Smith. Stephen Edward Smith died of cancer on August 19, 1990. … Smith died at her home in Manhattan on June 17, 2020, at the age of 92, being the last of John F. Kennedy’s siblings to die and the longest-lived Kennedy child.
Who was JFK’s sister?
Rosemary KennedyEunice Kennedy ShriverJean Kennedy SmithKathleen CavendishPatricia Kennedy LawfordJohn F. Kennedy/Sisters
Who is Joe Kennedy’s father?
Joseph P. Kennedy IIJoe Kennedy III/Fathers
How did the Kennedy family get rich?
Kennedy was born to a political family in East Boston, Massachusetts. He made a large fortune as a stock market and commodity investor and later rolled over his profits by investing in real estate and a wide range of business industries across the United States. … Kennedy later directed the Maritime Commission.
Was John F Kennedy the oldest child?
John F. Kennedy Jr.SonCaroline KennedyDaughterPatrick Bouvier KennedySonJohn F. Kennedy/Children
Did a Kennedy die?
November 22, 1963John F. Kennedy/Date of assassination


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A couple of weeks back I took a spin out to County Clare for a two-day road trip around a place that’s been the focal point of wanderlust for many a traveler the world over, myself included.
I can appreciate why.
I’ve visited Clare a handful of times over the years but it never fails to amaze. The trips never get old or repetitive. Most importantly – it always succeeds in leaving a lasting happy memory.
As if a couple of days out of the office, roaming around a county packed with natural beauty wasn’t enough to look forward to, Clare is also home to one of my favourite villages in the country – Doolin.
Perfectly positioned for many of the West Coasts most sought-after tourist attractions, Doolin offers the perfect cocktail of convenience mixed with traditional-Irish-country-lifestyle in one glorious mouthful.
If you’re planning a visit, here’s 7 things to do in Doolin that’ll arguably make you never want to leave this gorgeous little village.
1 – Get sorted with a place to rest your head
I never write about hotels or hostels. This isn’t that kind of travel website (not yet, anyway). The reason I’m mentioning it here is because my biggest regret from my last trip to Doolin was not getting a room there for the night.
I was stuck for time and was only raging that I’d miss out on an evening of wandering between the cosy little pubs scattered across the village.
Tip: if you stay near Fisher street (pictured above) in the winter months when darkness hits at around 17:00, you’ll be unable to walk safely to the pubs further down the road as there’s no footpath, and the roads are poorly lit (accurate at the time of writing).
You can just tell that once the live music kicks off, the place is absolutely hopping.
Honestly, grab a room for a night and soak up everything on offer! Anyway, you’ll be wrecked after finishing the rest of the activities below that’ll you’ll be glad of a place to catch a decent kip.
2 – Take the Doolin Ferry out to Inis Oírr (Inisheer)
I hate boats. No, really. I absolutely hate them. With a passion.
It could be down to movies like JAWS and the Perfect Storm, but it’s probably more likely due to the fact that I get seasick at the drop of a hat.
As you can imagine, getting me onto a ferry in the choppy Atlantic Ocean was no easy feat, but it was worth it. So if you get seasick, don’t let it put you off.
Doolin Ferry provides a boat to Inis Oírr from the village pier and it’s worth every penny.
The trip to the island takes just 30 minutes but when you arrive you’ll reach a slab of rural paradise off Ireland’s West Coast.
Rent a bike for a tenner and cycle along the narrow country roads, surrounded by hand-built stone walls that separate the different fields on the island. It’s like taking a step back in time.
I can’t even begin to recommend this enough.
Finish off your trip with a creamy pint of Guinness in the pub near the pier.
3 – Check out Moher on the Doolin cliff walk
If you’re staying in Doolin then the chances are you plan on wandering over to the Cliffs of Moher. If it wasn’t on your itinerary then get it jotted down sharpish!
The Doolin cliff walk is a unique and active way to experience the Cliffs of Moher and is run by local expert Pat Sweeney.
The walk kicks off early in the morning from Fisher Street in Doolin, just outside O’Connors Pub.
A handy walk if you’re staying in the village. If you have the car, there’s some limited parking just outside the pub but there are many more spaces down at the pier.
The walk takes adventurers towards Doonagore Castle and up to the walking trail along the Cliffs of Moher. As you walk, you’ll be greeted with spectacular views of the cliffs as they rise up into view in the distance.
If you can manage to tear your eyes away from the scenery along the route, Pat will take you through the history of the area, recounting memorable stories, myths and past memories.
If you plan on visiting the cliffs without the guide, they’re only a stones throw from the village with the journey only around 15 minutes in length by car.
4 – Mosey on down to the Doolin Cave
After a long walk along the cliffs, a trip to the Doolin Cave is a perfect follow up.
Armed with a roomy cafe out front, you can grab a coffee and a cake before you kick off the tour.
The Doolin Cave is home to the largest free-hanging stalactite in the Northern Hemisphere. Known as ‘The Great Stalactite’, it hangs from the ceiling like some giant cone-shaped chandelier.
Particularly mesmerising when you think it formed from a single drop of water many years ago.
Located in the Burren region in County Clare, the cave was formed around 350 million years ago but was actually only discovered in 1952.
The most recently opened show cave in Ireland, it opened to visitors in 2010 and now boasts a popular visitor center.
The tour itself packs a punch, taking visitors to the natural entrance of the cave, a stream sink at the base of a cliff face, through the main chamber where a guide turns on a light to illuminate the Great Stalactite.
Definitely worth a visit!
5 – Sample some of the best chocolate in the land
I’m not a huge fan of chocolate, but the stuff this place is churning out is just stupidly tasty. Known as the Doolin Chocolate Shop, it’s actually a sister company of Wilde Irish Chocolates where they’ve been perfecting their craft since 1997.
These guys create over 80 different chocolates out of a small artisan chocolate factory. We went for the white chocolate Oreo merengue. It tasted even better than it sounds.
6 – Cruise beneath the cliffs
One of the tours you can choose with Doolin Ferry involves cruising beneath the Cliffs of Moher on the return journey from Inis Oírr.
I’ve been to the cliffs twice before and loved each visit, but this is just a whole other ball game.
You get surprisingly close to the cliff face, and it’s only when you approach from below that you truly appreciate the sight of the 700 foot cliff that’s towering above you.
Couple the view with the fact that you’re on a relatively small boat that’s swaying side-to-side thanks to the rough Atlantic Ocean and you’ve an incredible experience, just waiting to be seized.
If you’ve got the time, I’d 100% recommend doing the Inis Oírr/Cliffs of Moher Ferry tour. You take a spin out to Inis Oírr on the ferry, spend a couple of hours on the island and then take a trip back along the cliffs.
7 – Grab a pint and some beef and Guinness stew in Gus O’Conners
After a ramble along the cliffs or a trip to Inis Oírr, the chances are you’ll be tired, hungry and probably cold/wet.
Gus O’Conners pub is the perfect spot to recharge the batteries.