text:
Cities | MiD-Day.com | Friday November 22, 2013
Police now believe that the possibility of the incident being a suicide is less and that Raju may have accidentally fallen off the high-rise.
World | Agence France-Presse | Friday November 15, 2013
A phantom body, clueless cops and busy spies: the fallout from the shooting of a senior Haqqani network leader will do little to dampen suspicions of Pakistani complicity with Islamist militants.
Cities | MiD-Day.com | Friday November 8, 2013
The mystery behind the headless body found in Chembur last week has been solved.
Cities | Press Trust of India | Thursday July 25, 2013
The mystery behind the unknown body of a murdered women found on the roadside from a posh locality in Ahmedabad two months ago was cracked by the city police crime branch today, with the deceased turning out to be the daughter of a former Gujarat min...
Indo-Asian News Service | Friday July 5, 2013
Filmmaker Mukesh Bhatt, known for producing successful films such as Raaz - The Mystery Continues, Jannat, Murder and Raaz 3, wants people to expect creative work from his camp.
Cities | Mid-Day.com | Tuesday July 2, 2013
A 26-year-old auto rickshaw driver's murder inside the vehicle in Malwani on Friday night has cops in a muddle. The mystery of the seemingly straightforward case deepened when the police realised that another murder had been committed in the same ric...
Indo-Asian News Service | Thursday June 13, 2013
Actor Emraan Hashmi says he felt he had reached saturation point with dark and intense roles in his decade-long film career, and that his forthcoming movie Ghanchakkar, a comedy entertainer, came as a much-awaited break for him.
Cities | Press Trust of India | Thursday December 6, 2012
The mystery surrounding a BCom student's brutal murder near Vambay colony in the outskirts of Visakhapatnam three days ago was unravelled on Wednesday after the police nabbed her lover and his friend.
Cities | Mid-Day.com | Thursday July 12, 2012
The announcement of a press conference was a dead giveaway that cops believed they had unravelled the most intriguing murder mystery, which has rocked Bollywood in recent times. Briefing the media on the Laila Khan case, joint commissioner of police ...
Cities | Mid-Day.com | Friday July 6, 2012
The Mumbai Crime Branch has arrested Asif Shaikh in an effort to solve the mystery shrouding the fate of starlet Laila Khan and her family, but it is not prepared to trust the suspect's confession just yet and is waiting to interrogate Parvez Ahmed T...
Cities | Mid-Day.com | Tuesday May 8, 2012
After the body of a 30-year-old man was recovered from the rocks of the Manori beach on Sunday, Gorai cops have learnt that the victim was called to the spot by a woman on Saturday. Cops are now trying to determine the identity of this mystery woman....
Cities | Mid-Day.com | Wednesday April 18, 2012
A shocking revelation made by the accused Vijay Palande in the sensational Karan Kakkad murder case points to a mystery politician, who was liaising with the two in a match-fixing racket. According to anonymous police sources, the relationship shared...
Press Trust of India | Saturday January 14, 2012
Harry Potter star Daniel Radcliffe has confirmed reports that he will be playing writer Allen Ginsberg in a new murder mystery.
Cities | Mid-Day.com | Wednesday January 4, 2012
After four-year-old Asifa Chaudhary's body was mysteriously found near Vile Parle (East) on the Western Express Highway (WEH) two days ago, her parents are crying foul, alleging police inaction. Cops meanwhile, have remained tight-lipped about the in...
Mid-Day.com | Friday August 5, 2011
The Dev. D star comes clean on the mystery man in her life, getting bolder on screen, and more.....
Cities | Mid-Day.com | Wednesday June 8, 2011
A gruesome murder on May 31, which left the police baffled for a while, was finally solved almost like a detective serial. During a study of the crime scene at Vinayaka Nagar, where Nymathulla (27), was brutally hacked to death with sharp weapons, the police found a severed middle finger beside the ...
World | Brooks Barnes, New York Times | Thursday November 18, 2010
Left with more questions than answers a day after a well-known movie publicist was shot to death on a winding side street here, a stunned Hollywood started scripting possible scenarios of its own. Was Ronni Chasen, a veteran press agent and Oscar strategist, simply the victim of a carjacking gone te...
Cities | DNA Correspondent, DNA | Tuesday October 26, 2010
Even though the police is more or less convinced about the suicide theory as far as Priyanka Ramanuj's death is concerned, there remains some doubt. It is because of the lie that Priyanka told her brother about her whereabouts.This is what has forced the police not to rule out the possibility of som...
Cities | Mid-Day.com | Wednesday August 11, 2010
The mysterious death of a 17-year-old girl in Mumbai has left the cops puzzled. The girl's parents allege that she would have been alive had the police taken timely action.The police said Sushma Pandey went missing on Saturday and was brought home in a drowsy state two days later by the owner of the...
Cities | Mid-Day.com | Monday May 10, 2010
What appeared to be a simple accident when a Delhi businessman rammed his car into an electric pole took a dramatic turn when the post-mortem result revealed that he was shot in the neck and might have died even before the accident.


AREA: An adaptive reference-set based evolutionary algorithm for multiobjective optimisation
Population-based evolutionary algorithms have great potential to handle multiobjective optimisation problems. However, the performance of these algorithms depends largely on problem characteristics. There is a need to improve these algorithms for wide applicability. References, often specified by the decision maker’s preference in different forms, are very effective to boost the performance of algorithms. This paper proposes a novel framework for effective use of references to strengthen algorithms. This framework considers references as search targets which can be adjusted based on the information collected during the search. The proposed framework is combined with new strategies, such as reference adaptation and adaptive local mating, to solve different types of problems. The proposed algorithm is compared with state-of-the-arts on a wide range of problems with diverse characteristics. The comparison and extensive sensitivity analysis demonstrate that the proposed algorithm is competitive and robust across different types of problems studied in this paper.
The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.
Citation : Jiang, S., Li, H.,Guo, J., Zhong, M.,Yang, S., Kaiser, M. and Krasnogor, N. (2020) AREA: An adaptive reference-set based evolutionary algorithm for multiobjective optimisation. Information Sciences,515, pp. 365-387.
ISSN : 0020-0255
Research Institute : Institute of Artificial Intelligence (IAI)
Peer Reviewed : Yes


text:
Tsukineko StazOn Pigment Ink Pad - Chocolate Brown
The staple mixed media ink StazOn just expanded with a brand new line of pigment inkpads.
StazOn Pigment works on all the surfaces that the original StazOn does and comes in a range of vibrant opaque colours. StazOn Pigment inkpads have an all-new felt pad that produces crisp stamped images and the ink dries quickly on most surfaces.
- Dries quickly on most surfaces including paper, metal, glass, plastic and acetate
- Can be used with embossing powder, even on non-porous surfaces
- Produces very crisp stamped images
- Vibrant and opaque ink colours
One 75 x 35mm ink pad.

domain: artistic


text:
Obesity is a serious risk factor for several chronic diseases, such as hypertension, cardiovascular disease (CVD), type 2 diabetes, respiratory disorders, and cancers. It incurs tremendous medical costs in both developed and developing countries [1
]. Therapeutic drugs to treat obesity reportedly cause several side effects related to blood pressure, hepatic failure, pancreatitis, and headaches [2
]. Therefore, safe and effective natural products for the treatment of obesity are desperately needed.
Consumers’ interest in consuming fermented foods containing live micro-organisms (probiotics) for their health benefits has driven research and marketing [3
]. The potential anti-obesity effects of probiotics have been reported in 3T3-L1 preadipocytes. In addition, Lactobacillus plantarum
FH185, L. plantarum
K21, L. gasseri
BNR17, L. gasseri
SBT2055, and Bifidobacterium breve
B-3 were found to prevent diet-induced body weight gain and obesity-related metabolic disturbances in rats and mice [4
Most studies on the health benefits of foods containing probiotic lactic acid bacteria have focused on live bacteria and, in fact, the live bacteria content is often related to efficacy. More recently, foods containing nonviable microorganisms or paraprobiotics that confer health benefits have gained research interest. Paraprobiotics are referred to as “non-viable microbial cells (intact or broken) or crude cell extracts (i.e., with complex chemical composition), which, when administered (orally or topically) in adequate amounts, confer a benefit on the human or animal consumer” [5
]. Recent studies have shown that the health benefits of a diet containing heat-killed lactic acid bacteria (HLAB) include reduced body weight gain, immunomodulation, increased intestinal barrier integrity, and a decreased number of enteropathogens [4
]. Moreover, they have advantages over live probiotics with regard to safety for immunocompromised subjects and the ease of standardization and preparation [4
Kefir, a fermented dairy beverage that originated in Eastern Europe, is a natural probiotic complex. It includes probiotic lactic acid bacteria (Lactobacillus
, and Streptococcus
spp.), acetic acid bacteria (Acetobacter
), and yeasts (Saccharomyces
, and Candida
spp.) in a symbiotic relationship. We and others have shown several health benefits of consuming kefir, which include cholesterol-lowering, antimicrobial, immuno-modulatory, anti-inflammatory, and anti-obesity effects [7
]. In addition, we have recently revealed the probiotic effect of Lactobacillus kefiri
DH5 (LKDH5), a bacterium isolated from kefir fermented milk—it inhibits the development of obesity and non-alcoholic liver diseases [10
Our previous studies showed that the supplementation of diet with wine grape seed flour (GSF), a byproduct of winemaking, suppressed high-fat (HF) diet-induced body weight gain, hepatic steatosis, visceral adiposity, and hyperlipidemia by the modulation of genes involved in oxidative stress, inflammation, and cholesterol and fatty acid metabolism [11
]. These effects were associated with a high content of flavonoids in GSF [13
]. We have recently shown that the combination of flavonoid-rich grape seed flour (GSF) and live kefir-derived lactic acid bacteria (LAB) improved HF-induced obesity and obesity-related metabolic disorders in a synergistic manner [14
]. However, the combined action of prebiotic GSF and paraprobiotic kefir HLAB has not been evaluated.
Our aim was to investigate the effect of kefir HLAB in combination with GSF, a bioactive polyphenol source, for their individual and symbiotic benefits in high-fat and high-fructose diet (HFFrD)-fed obese mice.
2. Materials and Methods
2.1. Animals and Diets
Four-week-old male C57BL/6J mice purchased from Orient Bio, Inc. (Sungnam, Korea) were housed under a 12 h/12 h light/dark cycle in an environmentally controlled room (temperature, 20–22 °C; relative humidity, 60%). The study was performed in accordance with all institutional and national guidelines for animal care and approved by the Animal Experiment Ethics Committee at Konkuk University (study protocol #KU16046 and KU17020). Prior to experimental diet initiation, the mice were acclimated for 1 week, during which mouse chow (PMI International, Redwood, CA, USA) and water were made available ad libitum. Thereafter, the mice (n
= 10 per each group) were fed a obesogenic, high-fat/high-fructose diet (HFFrD) containing 5% microcrystalline cellulose (CON, control diet; Dyets Inc, Bethlehem, PA), 2.5% grape seed flour (GSF), 2.5% GSF+HLAB, or HLAB for 8 weeks ad libitum (Table 1
). Ninety-nine percent of C57BL/6J mice became obese after eight weeks of the HFFrD diet (mice fed HFFrD diet increased body weight gain by 57% compared to chow diet group). HLAB suspended in saline were administered orally, and the CON and GSF groups were also administered oral saline. The composition of macronutrients and total dietary fiber, containing approximately 17%, 36%, and 47% calories from protein, carbohydrates, and fat, respectively, was matched across the diets (Table 1
). Chardonnay GSF was purchased from AprèsVin Enterprise, Inc. (Prosser, WA, USA), and its total phenolic content was analyzed using the Folin–Ciocalteu method. The HLAB were prepared from Leuconostoc mesenteroides
4 (LMDH4) and Lactobacillus kefiri
DH5 (LKDH5) previously isolated from kefir grain and cultured in lactobacilli Man, Rogosa, and Sharpe (MRS) broth (Difco, BD Biosciences, USA) at 37 °C for 48 h. After mass culture, the LAB were heat killed at 70 °C for 30 min. A 1 × 1010
CFU/mL culture of L. mesenteroides
4 (LMDH04) and 1 × 109
CFU/mL of L. kefiri
DH5 (LKDH5) were lyophilized. Before administration to the animals, the HLAB were rehydrated with sterilized distilled water at room temperature for 0.5–1 h. The HLAB were orally administered at 10 mL/kg body weight. The saline groups were administered by gavage at 10 mL of saline/kg body weight. Body weights were measured weekly, and food intake was monitored twice every week.
2.2. Sample Collection and Plasma Lipid Analysis
Following a 12-h fasting period, the mice were anesthetized in an induction chamber, using a vaporizer (VetEquip, Livermore, CA) containing 4% isoflurane (Phoenix Pharmaceutical, St. Joseph, MO, USA) with an oxygen flow of 1 L/min. Blood samples were collected using the cardiac puncture method using syringes previously applied with potassium EDTA solution (15% w/v). The plasma was collected and centrifuged at 4500 rpm for 10 min. After weighing, epididymal adipose tissue was immediately frozen in liquid nitrogen for further analysis.
Plasma lipoprotein cholesterol, triglycerides, and glucose concentrations were measured using a biochemical automatic analyzer (HITACHI, Tokyo, Japan).
2.3. Real-Time RT-PCR
Total RNA from epididymal adipose tissue was obtained using a TRIzol Plus RNA Purification Kit (Invitrogen, Life Technologies, Carlsbad, CA, USA). The cDNA was synthesized with 2 μL of total RNA using a PrimeScript RT Reagent Kit (Takara Biotechnology, Japan). A 2 μL sample of the diluted cDNA (1:10) was mixed with SYBR Green Supermix (Bio-Rad Laboratories, Hercules, CA, USA) as described in our previous study [14
]. The sequences of the primers are presented in Table 2
. Primers were verified by size and sequence analysis of the PCR products. Differences in mRNA expression were determined after normalization to the expression of 36B4 mRNA using the ΔΔ
2.4. Isolation of Cellular Exopolysaccharide (EPS) from Kefir Lactic Acid Bacteria
Cellular EPS from kefir LAB was extracted according to the previous method [19
] with slight modifications. L. kefiri
(LKDH1, 3, and 5) and L. mesenteroides
(LMDH04, 6, 7, 8, and 9) isolated from kefir grain (Konkuk University, Korea) [10
] were used. LAB strains were cultured in MRS broth for 48 h. The cultured broth was incubated with 80% trichloroacetic acid (Sigma-Aldrich, St. Louis, MO, USA) for 30 min in a shaking incubator. The mixture was centrifuged at 8000× g
for 20 min at 40 °C. Two volumes of ethanol were added to the supernatant and kept overnight at 40 °C. The precipitate was washed by suspending with two volumes of ethanol. The ethanol precipitation wash was repeated twice. The final precipitate was suspended in deionized water and dialyzed in deionized water for 48 h. The product was then lyophilized. Protein content in the EPS was analyzed using the Bradford method [20
]. The lyophilized EPS had less than 0.01% of protein in dry matter.
2.5. 3T3-L1 Cell Culture
The 3T3-L1 preadipocyte cells were obtained from the American Type Culture Collection (ATCC, Manassas, VA, USA). Cells were grown in Dulbecco’s modified Eagle’s medium (DMEM) with high glucose (Gibco, Grand Island, NY, USA), 10% bovine serum (BS; Gibco), and 1% penicillin streptomycin (P/S; Gibco). Two days after confluence (day 0), cells were cultured with differentiation medium (DMEM supplemented with 10% fetal bovine serum (FBS; Gibco), 1% penicillin streptomycin (P/S), 0.5 mM 3-isobutyl-1-methylxanthine, 1 μM dexamethasone, and 10 μg/mL of insulin (Sigma-Aldrich, St. Louis, MO, USA)). After 48 h, culture medium was replaced with complete medium (DMEM containing 10% FBS, 1% P/S, and 10 μg/mL of insulin) and incubated for another 48 h. On day 4, the cells were cultured with DMEM containing 10% FBS and 1% P/S for another 24 h. During cell culture, cells were incubated in a CO2 incubator (Thermo Fisher Scientific Korea, Seoul, Korea) at 37 °C with 5% CO2.
After differentiation, the cells were stained with Oil red O followed by the addition of 100% isopropanol to elute the Oil red O dye. Extracted Oil red O was centrifuged at 10,000× g for 2 min and the supernatant was transferred to a 96-well plate. The absorbance (OD) was measured at 480 nm and the percentage of intracellular lipid accumulation was calculated as (ODsample/ODcontrol) × 100.
2.6. Statistical Analysis
All data are shown as mean ± SEM. To determine the statistical significance of any difference between the control and treated groups, Duncan’s multiple range test of one-way variance (ANOVA) was performed. Pearson correlation analysis was applied to determine the correlation between mRNA gene expression and metabolic obesity physiological biomarkers. All statistical analyses were performed using SPSS software v20.0 (IBM SPSS Statistics, Chicago, IL, USA).
We have previously reported that a synbiotic combination of prebiotic polyphenol-rich grape seed flour (GSF) and live kefir-derived LAB improved HF-induced obesity-related metabolic disorders [14
]. In the present study, we revealed that supplementation with paraprobiotic kefir HLAB resulted in a significant reduction of body weight gain and adipose tissue weight in HFFrD-induced obese mice. Furthermore, the combination of prebiotic GSF and paraprobiotic HLAB induced a synergistic, positive effect on obesity and hypertriglycemia.
Selected probiotic strains, such as Lactobacillus
spp., Roseburia intestinalis
, and Akkermansia muciniphila
, have shown positive effects in obesity-induced metabolic disorders in animals. However, their effects in humans are inconsistent [22
]. Recently, several studies have revealed the health benefits of consuming HLAB on body weight, immunomodulation, intestinal barrier integrity, and enteropathogens [4
]. HLAB and their cellular components exert anti-inflammatory and immunomodulating activities through toll-like receptor 4 (TLR4) signaling pathways in HepG2 cells [25
] and THP-1 cells [26
]. TLR4 is one of the pattern recognition receptors responding to invading pathogens and regulating innate and adaptive immune, as well as inflammatory, responses in liver and adipose tissues [27
]. Mice lacking TLR4 have a significantly downregulated expression of genes targeted by peroxisome proliferator-activated receptors (PPARs). These studies suggest that HLAB modulate adipogenesis by regulating the expression of PPARs through TLR signaling. Consistent with previous studies, we show that kefir HLAB significantly reduced high fat- and fructose-induced body weight gain and adipose tissue weight gain compared with those in controls. More interestingly, HLAB significantly reduced the expression of genes associated with fatty acid synthesis (Fabp4
, PPAR γ target genes) and inflammation (Hp
), which indicates their possible role in fatty acid synthesis and anti-inflammation in adipose tissues. These beneficial effects were synergistically profound after HLAB were combined with 2.5% GSF. There were significant correlations between body weight gain, adipose tissue weight, and adipocyte expression of Fabp4
, and Hp
, indicating that the observed anti-obesity effect is mediated via the modulation of fatty acid synthesis and inflammation in adipose tissues.
We have shown that supplementation with 5% or 10% GSF inhibited HF diet-induced body weight gain, visceral adiposity, and hyperlipidemia by modulating the expression of genes related to oxidative stress, inflammation, cholesterol, and fatty acid metabolism in adipose tissues [11
]. Combining 10% GSF and live LAB improved obesity and obesity-related metabolic biomarkers through the action of prebiotic GSF and probiotic LAB [14
]. However, the observed synergistic effects were less significant due to the profound effect of 10% GSF itself [14
]. The present study has demonstrated a strong synergistic anti-obesity action using 2.5% GSF and HLAB.
The GSF ingredient contains 5.78 g of protein, 8.66 g of fat, 17.3 g of carbohydrates, and 57.3 g of total dietary fiber in 100 g (Table 1
). The composition of macronutrients and total dietary fiber, containing approximately 17%, 36%, and 47% calories from protein, carbohydrates, and fat, respectively, was matched across the diets (Table 1
). When a diet contains low carbohydrate content, energy expenditure increases, resulting in weight loss [28
]. Thus, the observed anti-obesity effect with HLAB is not related to the carbohydrate composition in the CON and GSF diets.
In our recent study [29
], 5% EPS (called kefiran) extracted from kefir grain showed greater anti-obesity effect in high fat diet-induced obese mice compared to 5% β-glucan (BG) although it has less viscosity than BG. More interestingly, 5% EPS significantly increased the abundance of Akkermansia
spp., a probiotic against metabolic diseases, compared to the control. Based on this study, it is hypothesized that the anti-obesity action of HLAB can be partially attributed to the cellular EPS component. Indeed, in the current study, inhibitory activity in the lipid accumulation in 3T3-L1 cells was greater in both EPSs from the HLAB, LKDH5 and LMDH4, that were used as paraprobiotics for the animal study. The amount of orally ingested kefiran in the previous mouse study was at least 500 times greater than in this study of the paraprobiotic HLAB. We estimate this based on 150 mg kefiran intake calculated from 3 g diet/d containing 5% kefiran and compared it to the 300 μg HLAB administered in this study. Taken together, while kefiran EPS has an effect, its potency compared to other cellular components in the nonviable LAB is considerably lower.
HLAB contain various cellular components, such as exopolysaccharides (EPSs), peptidoglycan, lipoproteins, and lipopeptides [30
]. Polysaccharide A (PSA) from Bacteroides fragilis
and EPS from Lactobacillus rhamnosus
GG induce TLR2-dependent responses in 3T3-L1 adipocytes and T cells [19
]. An additional function of EPS may be that EPS is a fermentable source of bacterial metabolites produced by the action of intestinal microbiota [32
]. Our previous study demonstrated that the consumption of 5% kefiran (EPS extracted from kefir grain) prevented high fat-induced obesity in an animal model [29
], which was associated with the modulation of intestinal microbiota. L. kefiri
DH5 (LKDH5) and L. mesenteroides
4 (LMDH04) used for present animal study showed the greatest inhibitory pancreatic lipase activity [33
]. Tannin polyphenols enriched in GSF have an inhibitory pancreatic lipase activity [34
]. The relative abundance of A. muciniphila
was increased by pancreatic enzyme therapy in chronic pancreatitis subjects [35
], supporting a close relationship between pancreatic lipase activities and the modulation of intestinal microbiota. Pancreatic lipase activity is most widely used to determine in vitro anti-obesity activity since it is one of the important enzymes in hydrolyzing triglyceride and thus absorbing lipids in the small intestine [28
]. The synergistic effect of GSF and HLAB in the current study could be due to the activation of multifunctional pathways by a combination of bioactive components (cellular components in HLAB and polyphenols in GSF), as well as the alteration of intestinal microbiota. Further study is required to determine the role of intestinal microbiota in the synergistic anti-obesity action of HLAB and GSF. These studies suggest that kefir HLAB are functional ingredients that can be used to alleviate obesity, especially in combination with GSF.
In summary, the combination of wine GSF and paraprobiotic kefir HLAB synergistically prevented the increase of HFFrD-induced body weight, adipose tissue weight, and plasma triglyceride concentrations. Cellular EPS extracted kefir LAB can lower lipid accumulation in 3T3-L1 cells, indicating that it can be a potential bioactive component to exert the anti-obesity effect of HLAB. The anti-obesity effect was in part mediated via a decrease in the expression of adipocyte genes related to fatty acid synthesis and inflammation, which was significantly correlated with obesity physiological biomarkers (body weight gain and adipose tissue weight).

domain: literature


text:
What really happened to Madeleine McCann?
Here at Happy Holidays we hope you enjoy the art exhibited. You will find art in many forms, crafts, stories, poems, and recipes from the Art of Cooking. This is a place to relax and
holidays, through, year, christmas, cheer, artesana, sierra, craft, crochet, knit, beading, quilt, along, #mystery, friends, recipes, cooking, sewing, recycle, crafts, yarn, thread, fabric, foam, food
Prepare to face a new set of challenges in this brand-new Pokemon world as you face new enemies and rivals, forge new friendships, and create teams to travel the world with in your quest
Home for the Mystery Science Theater 3000 Captions Project Team
Welcome to the Reawakened! You've entered a dark world full of magic and mystery, and I am your beloved admin, Aurora.
Based off the movie Hanna.
With Poetry, Literature, Short Stories, Mysteries Stories & Stuff At This Website
Mystery Manor Unofficial Fan Forum + Friend Code Synthesizer
Forum for the 4th season of my Mystery Big Brother series: Game of Thrones
The place to discuss everything Supernatural&The Vampire Diaries
This forum is for Mikey's Big Brother 3: Mystery Gotham City
This is a forum dedicated solely to Slender Man. Although there may be small talk of other paranormal beings/sightings, it is made especially for Slender Man and all of the mystery that sur
Game Development Forum. Mystery's Games Forum. mystery game development adventure maker riddle
This is Skyshatter. A place where all the magic and mystery in the world gets thrown away. We have learned to settle here, and live as a community. So all of your fantasy stories, your farirytale books, and your magical dreams, they're all real. And
Naughty or Nice
Newsletters, cheers, and more for Of Magick & Mystery web competition
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Visit, learn, discuss. Post comments and pictures. Get help solving the mystery of that mark or base or colour combination. Share insights and verify information with fellow glass lovers. Gloat and boast about recent finds. The place to go when eve
chalet, vintage, collectors, circle, visit, learn, discuss, post, comments, pictures, help, solving, #mystery, that, mark, base, colour, combination, share, insights, verify, information, with, fellow, glass, lovers, gloat
Free forum : A place to meet and talk about The Secret Society: Hidden Mystery game from G5 Games, available on iOS, Android and Kindle devices.
Welcome to Pokemon Mystery Dungeon RPG! Here you can Rol-Play as your favorite pokemon, explore dungeons, and work your way up to Lucario Rank!
League of magic . . . league of mystery. A mythical creature role-play site.
Forum for the third season of Kyogre's Mystery Big Brother Series.
Village Shrouded in Mystery. Rising Ninjas. Free forum ninjas Enemy new generation always surpasses the old Now we paint on our own stripes and leap into action tsu rising heavenforum
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Mystery Energy's Clan Forum
Free forum : Investigating The Madeleine Mccann Mystery

domain: entertainment


text:
The Department of Health, the HSE and a number of State-funded health agencies have refused to say which hospitals may have used faulty maternity unit monitors which are now the subject of an investigation.
The investigation into into the use at such units at 11 hospitals was ordered by the Department of Health after ‘communications’ were directed to itself, the HSE and the Health Products Regulatory Authority (HPRA). The investigation is examining the use of Philips made foetal CTG monitors used to check the heartbeats of mother and baby during labour.
The company issued a warning about the machines in 2009 because of the risk to mothers and babies.
The Department of Health declined to reveal which hospitals were subject to a review by a HSE Risk Assessment Team when contacted by the Leinster Express. In a statement the Minster for Health said the review ordered was prudent.
“The decision by the HSE to put in place a precautionary lookback, to check that monitors are being correctly used in our hospitals, is a sensible and prudent decision.
“It is right and proper that the HSE would take precautionary steps to ensure there is no patient safety risk.

domain: news


text:
Hand Reading Forum: palm reading & palmistry forum: psychodiagnostic chirology, life purpose hand analysis, vedic palmistry & multi-perspective palm reading!
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Darkness is rising and the Titans are at hand. Who can fight off their spawn and save the modern world?
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The best place to play your old classics in modern PCs!
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An Ancient Egyptian based RP with a few modern twist
Home of Modern Warfare 3's tacticalSix
First Person Shooting Clan.
A multi-platform gaming team created Christmas 2005.
Dogs of War is a PS3 gaming clan and community primarily focused on first person shooters. Members are mature gamers that respect each other. Games that members play are team focused including Battlefield Bad Company 2, Call of Duty Modern Warfare
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Free forum : A work in progress. Lets see how it goes
Modern Warfare/Xbox Clan
Official San Diego Elites Clan Forum! CoD:MW3 is the official game of San Diego Elites


text:
Download Davido Music Online for Free from tooXclusive.com
Press Release (ePRNews.com) - Nigeria - May 03, 2017 - tooXclusive.com is an online entertainment platform that exhibits new song releases as well as celebrity news that emerge periodically. They carry Nigerian content as well as those from other parts of Africa and have ranked highly due to the credibility of their content. They have established themselves, within the online community, so as to offer record labels, musicians, and managers their continuous skills, experience, and expertise that they have in the digital realm of music marketing. Their marketing campaigns use unique strategic methods which are set in place to maximize exposure completely, develop brand awareness and creating a grassroots movement.
Tope Delano, is a Creative Content Writer/Editor at tooXclusive.com states, “Singer Tekno, has declared that he alongside two other talented singers, rule the game. The RARA crooner, took to Twitter to make a claim tweeting that himself, Davido and Wizkid, are the three artistes, ruling the Nigerian music industry at the moment. This came after a fan tweeted that the three are the hottest in Africa. In other entertainment news, it is the rave of the moment. Davido is set to tour eight states in Nigeria including Abuja, Port-Harcourt, Enugu, Benin, Ilorin, Osogbo, Ibadan, and Lagos.”
After producing the monster hit ‘Pana’ for Tekno; Kriz Beats enlists the services of Tekno and Davido of their debut producer’s single titled ‘Erima’. It is extremely safe to call this number an extensive collaboration. Following their 2015 quarrel which had reports swirling around that Davido beat MC Galaxy at the latter’s Lekki home, which the former has denied. The hit, BomBom features DMW’s lead act, Davido and hype man, special Ed. Davido has alleged that new baby mama, Ayomide Labinjo, has again spoken on why the pair are involved in such dirty paternity scuffle.
Tope Delano continues to say, “Davido, who spoke to ‘This Day Style’ asserted that he signed a couple of artistes to his new record label, Davido Music Worldwide-DMW. In their team are, Mayorkun, Dremo, Ichaba, Danagog, and recently, Dammy Krane. These guys all rely on Davido as their mentor. Mayorkun and Dremo have top charting songs and are making waves in the music industry at the moment. Danagog has also been on for a while and he has some good music out there. Davido is currently working on new materials for Ichaba and Dammy Krane.”
Lately, superstar and big money spender, Davido, was the highlight at the Big Brother Naija 2017 eviction show where the singer performed Africa’s number one song, ‘IF’. While razzle-dazzling on his music set, many fanatics might have missed these developments. In the meantime, Davido has recently decided to keep the singer’s beards with a new style of keeping his facial hair with tiny trim cuts running from both ends of the musician’s jawline all the way to the lower chin region. Fanatics can engage them to download Davido music online.
tooXclusive.com delivers entertainment news in Nigeria and features songs of artistes on their site. They are currently getting Over three million hits worldwide a month and still counting. Fans can get their own artist profile page on tooXclusive.com. Also, their platform helps distribute songs to many fans through social networks, news and press releases.Source : tooxclusive


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"This album is personal," says Mitchell. "There's a lot of thinking about my own kind of mythology - of myself, my life, why things are the way they are. And a lot of it is to do with childhood."
Though 'Warriors' is her third album, Mitchell's adolescence is still recent history. At just 26, the musician has built a catalogue to rival elders. Mitchell's debut EP was released when she was just 17, her second at 18; both accomplished folk pieces harbouring pop ambitions. Her full-length debut, 'Wonder,' delivered on its promise, reaching No. 6 in Australia and achieving Platinum status. Her follow-up, 'Bless This Mess,' introduced a wider sonic scope, tethering lush piano-driven pop to jangly, rock flourishes. While acoustic guitar remains Mitchell's primary songwriting tool, for her third album she decided to shake things up.
"We really got rid of a lot of guitar and piano in this album," says Mitchell. The "we" she refers to is US producer Eric J Dubowsky (aka Eric J, who has worked with Chet Faker, Flume, The Rubens), who until Warriors had never worked with Mitchell. "I was interested in someone doing a different thing than what I'd done in the past," she says. "That felt refreshing."
Mitchell and Dubowsky set up in Sydney's Hercules Street Studios in Surry Hills and roped in drummer Matt Johnson (Jeff Buckley, St. Vincent), bassist Rob Calder (Angus & Julia Stone/Passenger), and regular guitarist and collaborator, Tim Harvey (who also co-wrote with Mitchell in pre-production) to back Mitchell's songs. The duo sought a lightness of groove that hadn't previously been a focus of Mitchell's music. It mirrors a shift in both her listening habits and personal taste. "I've definitely been doing a lot more dancing in life," says the singer. "I'm sure a lot of the dance music is infiltrating into my writing. I feel this album is good with motion."
First single The Boys details a sunny day Mitchell drove around Sydney in a car of male friends all mourning the passing of a mates' dad. Over a bed of skittering percussion and a loping amble, the song is a literal account of the collective bonhomie in a coded situation.
|Primary Format - Music||CD|
|Music Genre||Singer/Songwriter / Pop|
|Music Genre Primary||Pop & Rock|
- 1. The Boys
- 2. Warriors
- 3. Warhol
- 4. Unravelling
- 5. So Wild
- 6. I Remember Love
- 7. What Is Love
- 8. Where You Are
- 9. Josephine
- 10. Love, Death X
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- 1 Extra Information About b cell lymphoma in dogs life expectancy That You May Find Interested
- 1.1 Lymphoma in Dogs Fact Sheet | Davies Veterinary Specialists
- 1.2 Lymphoma In Dogs: Types, Symptoms, Treatment, Life …
- 1.3 What is My Dog's Life Expectancy With Lymphoma? A Vet …
- 1.4 Lymphoma – Pet Cancer Society
- 1.5 Canine Lymphoma – Ethos Veterinary Health
- 1.6 Improving the Odds of Surviving Lymphoma – Tufts Now
- 1.7 Lymphoma in Dogs – The Pet Oncologist
- 2 Frequently Asked Questions About b cell lymphoma in dogs life expectancy
- 2.1 How long will my dog live after receiving a lymphoma diagnosis?
- 2.2 Do canines with lymphoma endure pain?
- 2.3 Is B cell lymphoma in dogs treatable?
- 2.4 What are the canine lymphoma final stages?
- 2.5 How quickly does canine lymphoma develop?
- 2.6 How long can a dog with lymphoma survive on prednisone?
- 2.7 What caused my dog’s lymphoma?
- 2.8 Which type of lymphoma in dogs is worse, T or B?
- 2.9 Should a lymphoma-ridden dog be walked?
- 2.10 Can a dog take prednisone forever?
- 2.11 What are prednisone’s worst canine side effects?
- 2.12 What is the most typical age for canine lymphoma?
- 3 Video About b cell lymphoma in dogs life expectancy
Below is information and knowledge on the topic b cell lymphoma in dogs life expectancy gather and compiled by the baonangluong.info team. Along with other related topics like: .
in Dogs Fact Sheet | Davies Veterinary Specialists
Lymphoma in dogs is primarily a cancerous condition of the lymph glands.
It can also affect other organs such as the liver and spleen and occasionally we see forms of lymphoma in dogs apparently only affecting a single site such as the skin. As a general rule lymphoma affects anatomically distinct sites throughout the body. Therefore specialist dog oncology treatment must likewise treat the whole body.
What is Lymphoma in dogs?
Lymphoma is a cancer of the lymphocytes, or white blood cells. There are multiple different types of lymphoma in dogs, just as there are in humans, though at the moment this is really a concept that is only just reaching the wider veterinary consciousness. The different types of lymphoma arise from malignant transformation of different types of lymphocytes or as a consequence of different specific DNA aberrations acquired during the life of the individual patient. Most lymphoma types respond favourably to the administration of chemotherapy. There are some that do not and it is important to attempt to identify these cases as other treatments may be indicated.
The life expectancy with most types of lymphoma in dogs is limited to only a few months. With chemotherapy protocols, this is increased to an average of 6½ to 12 months depending on the treatment plan.
A diagnosis of lymphoma in dogs is usually made on examination of a pathological specimen. This might be a fine needle aspirate biopsy of an enlarged lymph node or other structure or it may be a histopathological examination of a bigger biopsy specimen. At the current time, most diagnostic evaluations stop once the diagnosis of lymphoma has been made. As alluded to above, this is not always ideal. Further evaluations can be performed including immunocytochemistry and cytomorphological and histomorphological assessments. Classification of canine lymphoma into the different subtypes will allow us to provide more specific treatment and to provide more precise estimates of prognosis.
At the moment only a few of the more common subtypes have been fully characterised; as time passes and more experience is gained this will improve. Some alternative, novel therapies are likely to arise for the less common disease presentations and improved outcomes will be seen in the more common subtypes.
Other evaluations are important to understand the general health of the patient before decisions about chemotherapy are taken. These include blood tests and possibly x-rays and ultrasound evaluations. Some types of lymphoma are associated with high blood calcium concentrations, hypercalcaemia. It is important for the well-being of the patient that complications like this are identified and managed appropriately.
There are countless chemotherapy treatment plans (or protocols) that have been described for the management of canine lymphoma. The principal candidates are described as multidrug chemotherapy protocols. They incorporate the three drugs Cyclophosphamide, Vincristine (Oncovin) and Prednisolone, usually called the COP protocol, or the same three plus a drug called doxorubicin (Hydroxydaunorubicin) usually called the CHOP protocol. The COP protocols have a reduced chance of inducing unwanted side effects but carry a reduced probability of inducing a complete remission. The average life expectancy on this treatment to lymphoma in dogs is approximately 6½ months. The CHOP protocols achieve complete remission in a higher percentage of cases and the average life expectancy is improved as a consequence to approximately 11½ months but the risk of unwanted side effects is that little bit greater.
The decision about which treatment plan to choose should be made in conjunction with your veterinary surgeon, whether they are your local vet or your oncology specialist. This is not a one-size-fits-all situation. Some veterinary practices will very sensibly only offer a single lymphoma protocol. The rationale here is that they see a reduced number of cases compared to a veterinary oncologist; therefore it is important for optimal familiarity with the disease in question and the possible range of manifestations of tumour and treatment response that every member of staff in the practice is used to using the same treatment plan, otherwise things start to get very confusing and chemotherapy is not a thing to be confused with. Other factors influence treatment choice such as accessibility of a specialist centre, cost of therapy, duration of therapy and of course the patient’s own response to the drugs once they have been administered.
Chemotherapy induced side effects are usually minor if indeed they are noted at all. Nevertheless it is critical that the risk of these effects is addressed and discussed openly prior to the onset of therapy. In many cases the improvement in the patient’s condition substantially outweighs the minor impact of the treatment related side effects leading to an overall improvement in general health despite chemotherapy.
Quality of Life
It is tremendously important to emphasise that patients undergoing chemotherapy (or any other cancer therapy for that matter) do so because their team of carers, the primary veterinary surgeon, the veterinary oncologist and the family at home, all feel that the treatment is improving quality of life at all times. Chemotherapy and cancer rightly carry a certain stigma. We take great pains to ensure that any potential side effects are discussed fully prior to embarking on a course of cancer therapy. This way our owners make informed decisions about the treatment choices they have for their pets. The aim of our cancer therapy is to promote a good quality of life first and foremost and life expectancy second.
Extra Information About b cell lymphoma in dogs life expectancy That You May Find Interested
If the information we provide above is not enough, you may find more below here.
Lymphoma in Dogs Fact Sheet | Davies Veterinary Specialists
Lymphoma In Dogs: Types, Symptoms, Treatment, Life …
What is My Dog's Life Expectancy With Lymphoma? A Vet …
Lymphoma – Pet Cancer Society
Canine Lymphoma – Ethos Veterinary Health
Improving the Odds of Surviving Lymphoma – Tufts Now
Lymphoma in Dogs – The Pet Oncologist
Frequently Asked Questions About b cell lymphoma in dogs life expectancy
If you have questions that need to be answered about the topic b cell lymphoma in dogs life expectancy, then this section may help you solve it.
How long will my dog live after receiving a lymphoma diagnosis?
With chemotherapy protocols, this is increased to an average of 612 to 12 months depending on the treatment plan, whereas the life expectancy with the majority of canine lymphoma types is only b>a few months/b>.
Do canines with lymphoma endure pain?
In fact, many dogs with lymphoma are taken to the vet because the owner feels lumps under the skin in the vicinity of the lymph nodes (under the chin, in front of the shoulders, or behind the knees). Lymphoma is not typically a painful cancer in dogs.
Is B cell lymphoma in dogs treatable?
Less than 10% of dogs with canine lymphoma are still alive two years after diagnosis, meaning that the disease is b>rarely cured/b>.
What are the canine lymphoma final stages?
If the lymph nodes are very large, they can affect breathing because they are blocking the throat. You may notice that your dog has trouble breathing or noisy inhalation (stertor). Lymphoma: End-stage disease can cause dogs to act very lethargic, vomit, have diarrhea, eat less or have no appetite, and lose weight.
How quickly does canine lymphoma develop?
If untreated, the majority of dogs develop terminal stages one to two months after initial presentation, with high-grade lymphomas typically being high-grade and progressing quickly.
How long can a dog with lymphoma survive on prednisone?
Some owners opt not to treat dogs who develop lymphoma, and the life expectancy of these untreated dogs is typically 4 to 6 weeks. The average survival time for patients with lymphoma treated with prednisone alone is 60 days.
What caused my dog’s lymphoma?
Unfortunately, the exact cause of lymphoma in dogs remains unknown, despite extensive research into a number of potential culprits, including viruses, bacteria, chemical exposure, and physical elements like intense magnetic fields.
Which type of lymphoma in dogs is worse, T or B?
Dogs with T-cell lymphoma treated with multiagent chemotherapy have reported median survival times of 8 mo, whereas dogs with B-cell lymphoma treated with the same protocol have median survival times exceeding 15 mo. T-cell lymphoma is typically associated with a worse prognosis.
Should a lymphoma-ridden dog be walked?
Short Walkbr> br> While your dog may be a little less than their best due to lymphoma, that doesn’t mean they wouldn’t enjoy a quick stroll outside. In fact, a little exercise can help your dog maintain peak health while fighting cancer.
Can a dog take prednisone forever?
Short-term prednisone use has fewer side effects than long-term use, so most veterinarians will only prescribe it for a short period of time. The longer your dog is given prednisone, the greater the likelihood that your dog will experience negative side effects. Long-term prescriptions last about three to four months.
What are prednisone’s worst canine side effects?
Prednisone can affect the gastrointestinal tract, resulting in vomiting, diarrhea, GI ulceration, or bleeding. Dogs may develop a pot-bellied appearance as well as a poor haircoat or hair loss, all signs of Cushing’s syndrome. Long-term use or high doses may result in more serious issues.
What is the most typical age for canine lymphoma?
One in every 15 dogs born today is predicted to develop lymphoma at some point in his life, most likely in late adulthood (between the ages of 8 and 11), making it one of the most prevalent cancers seen in dogs. Lymphoma actually occurs in dogs 2 to 5 times more frequently than in people.

domain: medical


Singing is for all including the instrumentalist. This basically means that all who truly desire to sight sing can learn singing or music reading once they get a teacher. Though this article is not about music education pros and cons, noting that Zoltan Kodaly (16/12/1882 to6/3/1967) believed that early music education was a factor of bringing his Hungary nation to a heightened culture and music level is quite interesting. So here are our tips for boosting your practice.
Begin early and get an excellent teacher
In some nations, people that lack musical education are considered to be illiterates. Almost all individuals in such nations, sing, play instruments, and their concert halls are always full. How is it that even nations with a moderate population of ten million citizens have eight hundred concert choirs? Fifty among them rank while another hundred of public or radio performance quality just like choir concerts in Los Angeles.
Join an excellent choir and attend concerts
What would changing, the musical tastes and abilities of a whole nation take? For most nations, it’s a matter of getting everybody not just the upper class to raise music teaching standards, involve young children’s education, and get many to become interested in creating music. Making individuals become aware of their musical heritage is always a large component of helping them to connect with each other and with their inherited music. You must always do whatever is needed to raise your own standard by boosting your own singing.
One major reason for which sight singers excel is, understanding the various parts of music and musical instruments. This enables them to sing songs in the works they are preparing, and prepare adequately in advance for any sight readings they might have to execute instantly. If you can follow these tips to the letter, then doing these two things will certainly become easy, even if you are performing in a choir concert. That is what sight singing practice does for you.
Every person has his or her own preferences. It is sure that you have your own likings. However, in the recent years, the field of music has become different in this regard. The admirers of classical music do not get their favorite music with ease. That is so because the rapid growth of popular music or ‘pop’ music has changed the scenario completely. You will not see many people listening to classical music anymore. Nevertheless, the following points will help you in understanding if you would like classical music or not:
You like listening to simple sounds:
The simple and joyous sounds of nature could cheer you up. Try listening closely to the chirping of birds in the morning and you will realize if you like listening to it or not. While some people are too impatient and they do not like such sounds, it is certain that some people are the completely opposite. If you sit and listen to such sounds of the nature, you will realize whether you like listening to them or not. If you like, then it is sure that you would love listening to classical music.
You love patterns:
If you like, seeing patterns in your life, then the complex music patterns of classic music will attract you like a magnet. You can look for a choir concert near you and it is certain that you would love listening to it.
You like relaxing music:
Even in the current time of electronic music, you can find some relaxing music to soothe your senses. A choir concert is always relaxing but if you love the relaxing music then you would enjoy it as well. Classical music is of a different class and you would admire it too if you admire relaxing music and tones. You will not have any problem in this regard.
As more people begin to lose interest in attending theatre events, the popularity of orchestras and related events has reduced drastically. But, this is mainly because of the misconception that is associated with issues patterning to orchestras. Today, there are exceptional choirs that host mind staggering choir concerts. Attending such events would be a perfect idea based on the long list of advantages that are associated with them. Most importantly, they are among the best ways to pass time. If you want to enjoy your holiday, a long weekend or any free time, you can do well to attend a reputable choir concert. The best choir concerts worth attending are those that are organized by world renowned choirs. This is mainly because of the numerous pros that come with attending such concerts. Some of the major reasons why such concerts attract many people are indicated below.
Listen to unique music;
Witness the performances of some of the world’s most renowned choirs. This is obviously an amazing experience that you cannot afford to miss. Reputable choirs are able to come up with music that is unique and hard to forget.
A perfect way to pass time;
Suppose you have a long weekend and you wish to watch it pass without feeling bored at any given moment, you can travel to a destination which is hosting a choir concert LA. Reputable choir concerts are often hosted by special destinations around the world. It does not matter whether you have a short or long weekend, you can attend such concerts as long as you have the means of travelling to the location. There are some choir concerts that are hosted during the holidays. You can attend such events too.
Without any doubt, attending a reputable Choir concert Los Angeles comes with all the benefits indicated. Attend one if you want to have a memorable experience.


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San Fran got lucky last night! Teyana was wrapping up her performance when she brought a special guest onstage — Yeezy! Take a look at their concert collab.
What a pair! Kanye West, 41, and Teyana Taylor, 27, performed their single “Hurry” on the Sept. 5 stop of her K.T.S.E. tour in San Francisco. Fans freaked for the surprise duet because, even though their collab is on her album and both artists are signed to G.O.O.D. Music, no one had any idea he’d be making an appearance. And what an appearance it was! Kanye didn’t just do the song with Teyana — and give her a big ol’ hug at the end — but he stuck around onstage for another song, watching her perform with his phone out like the rest of the fans.
And we don’t blame him! Teyana was a powerhouse and put on a seriously unique performance. Not only did she make a stylish statement in her white cropped tank and cutout pants, but she made a statement for social justice as well. “We going to sing this song for everybody that turned they back on Colin Kaepernick,” she said before singing “Gonna Love Me.” She had fans put their fists in the air and did the same herself. Behind her was a photo of the football player — and new Nike frontman — who faced backlash for refusing to take a knee during the National Anthem as a protest against police brutality in America.
She had her two-year-old daughter Junie onstage with her for the major moment, so technically Kanye wasn’t the rapper’s only special guest!
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This isn’t the first time that Teyana and Kanye — and Junie! — have worked together on a fire collab. Although Post Malone and Ty Dolla Sign lent their voices to Kanye’s 2016 single “Fade,” Teyana danced in the sultry video with her husband Iman Shumpert and daughter only three weeks after giving birth.

domain: celebrity


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East Bay News
Suspect injured in officer-involved shooting in Dublin
DUBLIN, Calif. (KGO) -- One person was injured in an officer-involved shooting in Dublin Friday morning. Police say it happened around 9:30 a.m. on Fredericksen Lane near Fredericksen Elementary School.
The incident was over in just two minutes. It started with a call from a father who was concerned that his 28-year-old son was acting strangely. The man came out holding a large knife and the officer opened fire, hitting the suspect at least once, in the arm.
Authorities say law enforcement had been in minor contact with the man before. "He does have some assault history, and some threatening behavior history, and possibly some mental history," said Sgt. J.D. Nelson with the Alameda County Sheriff's Department.
"When the deputy got here, it was very quick, within two minutes from the time he got here, he was confronted by the suspect with a very large 12-inch Rambo-style knife, charged at the deputy, the deputy fired. The suspect dropped the knife and the deputy was able to take him into custody," Nelson explained.
The school was never affected by the incident despite being just a short distance away.
The deputy fired more than once, but it's unknown how many times the suspect was hit. "He's been on 8 years. He's a very well-respected deputy and he was confronted with a very difficult situation, someone coming at you with a Rambo-style knife, and he took immediate action, and was able to render the suspect into custody," Nelson said.
The investigation into why the man charged deputies continues.
dublin, crime, shooting, alameda county, east bay news, laura anthony
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- roundup: SF shooting; Milpitas possible kidnapping
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domain: law


Equinox Grey White Quilted Bedding Comforter – Goose Down Alternative – Reversible Soft Twin Duvet Insert Set – Washable – Lightweight-Plush Microfiber Fill Comforters (350 GSM)(Twin – 68 x 86 Inches)
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|Item type||Location||Collection||Call number||Status||Date due||Barcode||Item holds|
|PS Picture Book||
|Book||PB H (Browse shelf)||Available||0370525555|
|EY Picture Book||
|Book||EY H (Browse shelf)||Available||0328395555|
|EY H Spot loves his friends||EY H Spot loves his grandpa||EY H Spot loves his grandma||EY H The Truth according to Arthur||EY H I went to the supermarket||EY H Happy birthday Peter!||EY H Corduroy gets a pet|
Arthur had disobeyed his mother and ridden his brother's bike. Unfortunately he accidently damaged it (and his mother's car!) so decided to try to hide the truth to avoid trouble with his mother. However, when he decided to own up he found that honesty was a better choice.

domain: library


When was the last time you saw a Westport youngster walking or riding a bike to school?
There’s a reason the answer is “back in the Ford administration.” For reasons both societal (parents enjoy driving their kids) and calculated (the town has decided to not create bike lanes; not build or improve sidewalks, and not install bike racks), Westport’s roads and parking lots are clogged each school day with the vehicular version of atherosclerosis.
I won’t say the result is an epidemic of fat kids.
I’ll let Michelle Obama say it for me.
Yesterday the First Lady announced a sweeping initiative to eliminate childhood obesity within a generation. Part of the effort includes installing sidewalks in neighborhoods to encourage students to walk to school.
She said that a series of small changes — as simple as repainting crosswalks with reflective paint so more children could safely walk — slows the rate of childhood obesity.
A couple of years ago, Bedford’s security guard counted 300 parents dropping kids off — in a single day. That’s in addition to the many school buses that crawl through town — often moving slower than a child can walk or bike.
Let’s get off our butts on this one.
So our kids can get off their theirs.


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BELFAST, Northern Ireland – The Irish Republican Army (search) declared for the first time Thursday that it's willing to get rid of its entire weapons stockpile within weeks - but it won't allow anybody to photograph the disarmament.
The outlawed IRA made its new offer of speedy disarmament a day after the British and Irish governments published a detailed plan designed to revive a Catholic-Protestant administration, the intended cornerstone of the province's Good Friday (search) peace accord of 1998.
The two diametrically opposed forces that would have to share power - the British Protestants of the Democratic Unionist Party and the Irish Catholics of Sinn Fein, the IRA-linked party - agree they are close to a historic pact.
But just as the IRA's longtime refusal to disarm has wrecked previous power-sharing pacts, its refusal to permit photos of its disarmament has become the deal-breaker this time.
All sides agreed Thursday that the IRA's latest commitments represent a stunning advance from 1997, when the underground organization halted its 27-year campaign against British rule, which left 1,800 dead and tens of thousands injured.
At that time, IRA activists plastered walls with the defiant slogan "Not a bullet, not an ounce." This meant the IRA would cling to its massive arsenal - largely supplied by Libya in the mid-1980s and hidden in underground bunkers - as its most valuable negotiating card.
In Thursday's statement, the IRA confirmed British and Irish claims that it was ready to play its ace - but also that its new slogan has effectively become: Not a photo.
The IRA's seven-man command said it has conditionally agreed to lead disarmament officials to all of its remaining weapons bunkers "speedily and, if possible, by the end of December."
It will allow two clergymen - one a Catholic priest approved by Sinn Fein, the other a Protestant nominated by the Democratic Unionists - to act as independent observers, another new commitment.
In other significant pledges, the IRA moved closer to demands for the group to fade away as part of a new power-sharing deal.
It said it would instruct its membership - estimated at less than 1,000 people organized in small units - "not to engage in any activity which might thereby endanger that new agreement."
But the IRA said it must reject one section in the Anglo-Irish plans published Wednesday:
- That the IRA should permit an internationally respected photographer to record the entire disarmament process;
- For these photos to be shown to leading Protestant politicians confidentially once Northern Ireland's legislature convened in January;
- And for the photos to be published in March on the same day that lawmakers elected a new administration led jointly by the Democratic Unionists and Sinn Fein.
The IRA said Democratic Unionist leader Ian Paisley "demanded that our contribution be photographed, and reduced to an act of humiliation. This was never possible."
Sinn Fein chairman Mitchel McLaughlin said Protestants instead must accept as sufficient the IRA's offer of independent witnesses.
"The photographs have been ruled out and we should just accept that as (being) a bridge too far," McLaughlin said.
But the Democratic Unionists declared its readiness for a protracted standoff if the IRA doesn't budge on permitting photos.
"If there is going to be an impasse over decommissioning, then it could go on for a long time," said Democratic Unionist negotiator Jeffrey Donaldson. "Republicans are going to have to revise their position."
The British and Irish governments agreed that IRA disarmament must be sufficiently "transparent" for the public, particularly the Protestant majority, to support power-sharing with Sinn Fein.
Britain's governor for Northern Ireland, Paul Murphy, said he understood Sinn Fein-IRA worries that Paisley could use photos to rub the movement's nose in surrender claims.
"At the same time," Murphy said, "unless we are able to give confidence to people throughout the whole of Northern Ireland that decommissioning has happened, then this simply isn't going to work."


text: The elasticated waist on these straight leg Kenzo pants keep them super comfortable. Printed in moody tones of green and blue, the silk composition makes them an unexpectedly luxurious choice. Blue and green printed silk, elasticated waist. Slim fit, straight leg. Pair with a fitted pullover and ankle boots. 96% Silk, 4% Elastane. Dry clean. This item runs true to size.

domain: design


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If you zynga poker online are actually a supporter of Zynga’s games, you will desire to know even more about its own newest mobile game, “Zynga Poker”. This activity is actually created by Zynga along with the customer in thoughts and delivers a fantastic experience along with a range of means to play.
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You can easily decide on to play for amount of money, or bet cost-free. When you participate in for money, you will be actually inflicted seven memory cards, and you need to pick one memory card coming from each fit, so as. You will certainly at that point be actually dealt 2 more cards as well as are dealt individually. You are right now called for to choose the card in your palms that is the exact same as the one that you decided on out to begin with in the game.
You will after that participate in a round of Online poker, where your cards will definitely be put skin down. Throughout play, you can see which memory cards are actually presently in your rivals’ palms, as well as exactly how many of those memory cards are actually still in the deck.
The video game may be bet enjoyable, or as a very competitive video game. As you carry on playing the activity, your challenger’s memory cards will certainly receive closer to yours, however if you have the capacity to keep your very own cards near your own, you will increase your odds of gaining. If you have the ability to stay near to your rivals, you will increase the opportunities of winning, and you are going to ultimately acquire a much higher credit rating.
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If you are seeking a new Zynga Texas hold’em game to play, you can possibly do so with Google.com Play, which supplies a selection of these activities. The Zynga Casino poker mobile activity is actually a fantastic method to entertain on your own with some enjoyable and enjoyment while you are actually waiting on a lengthy time. You may play it once more to appreciate the take in that it gives you when you are actually done participating in the game.
Most video games online are readily available in English, however there are actually also some that are accessible in Spanish and various other languages. The Zynga Casino poker video game is actually offered in even more than 50 countries, and also is actually the very most well-liked on-line texas hold’em video game.
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If you are a seasoned gamer, you can carry on betting as long as you prefer and can go up from degree to level as you end up being a lot more skilled. There are even complimentary trial video games available for folks that wish to check out the game and also view exactly how it operates before they purchase it.
Zynga Casino Poker Online Mobile Video game is actually the latest model of their Zynga Poker Game. The current version of this particular Zynga Poker Video game possesses more functions than the previous variations of the Zynga Casino Poker Video Game, and this brand new version of the Zynga Online poker Video game can be actually participated in on both cell phones and also various other tablet Personal computers like ipad tablets. The game is actually based upon the timeless Zynga Poker Video game and also is incredibly popular along with casual gamers as well as hardcore casino poker players.
Because of all the various functions that it offers its own players, the Zynga Online Poker Online Mobile Activity is actually very prominent. It possesses a real-time online poker casino which enables players to play versus each various other and win cash coming from these video games. The game additionally possesses a selection of options for different forms of players, and also it has many different techniques to make money coming from it. Zynga has taken fantastic like make the various alternatives for different gamers so that they can easily conform exactly how they like to. You can easily decide on whether you wish to conform on your iPhone or even on a tablet COMPUTER, and the Zynga Casino poker Game will work with all kinds of players irrespective of their capability degree or capacity.
There are actually a number of various methods that you can utilize so as to gain your money and acquire a big stack of funds when you rest down to participate in the Zynga Poker Activity. The different methods that you may utilize depend on what style of player you are, as well as whether you like playing the video game with your close friends or along with various other gamers online.

domain: game


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Jackie Chan might still be popular in China, but nowadays the pro-Beijing actor is as well-known as fodder for jokes as he is for his gritty martial arts.
When Chan last visited India in 2013, he spoke about the need to encourage movie collaborations and cultural exchange between the two countries.
The bid committee in China hoping to bring the 2022 Winter Olympics to Beijing has roped in Jackie Chan to record a song that will be used to help promote the country's 2022 Olympic campaign.
Jaycee Chan was arrested from his residence in August last year along with 23-year-old Taiwanese movie star Ko Chen-tung for housing others to take drugs.
Celebrities including movie superstar Jackie Chan and former NBA player Yao Ming serve on the panel.
There's Jackie Chan, John Cusack and Adrien Brody in this period drama if you were looking for a performance you would want to talk to friends about.
The Italian consulate in Mumbai and the Indo-Italian Chamber of Commerce hosted a party at a plush Mumbai hotel as a preview to the Italian Expo.
Actor Akshay Kumar has wrapped up shooting for Dharma Productions' "Brothers", which he says has turned out to be a "memorable" film.


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domain: finance


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This 1993 Chevrolet Corvette ZR-1 has remained in California from new, spending much of its life in San Diego prior to being acquired by the seller’s parents in 2016 and relocated to Palo Alto. Power comes from a 5.7-liter LT5 V8 paired with a 6-speed manual gearbox, and modifications include a Lingenfelter rear differential and yellow KONI Sport shocks. Recent work included Redline gear oil, a new coolant temperature sensor, EBC Yellowstuff brake pads, fresh spark plugs, and more as detailed below. Now showing just over 22k miles, this coupe is offered with a clean Carfax report, records dating to 1993, and a clear California title.
The car was blocked, sanded, and repainted in its original Black (41) under previous ownership. The paintwork was performed by Amato Auto Body in San Diego, California and is shown in a number of up-close photos below.
Stock 17″ aluminum alloys measure 9.5″ up front and 11″ out back and are wrapped in Goodyear Eagle F1 tires. The retractable headlamp motors are described as noisy by the seller.
Black leather seat upholstery is accented by 40th Anniversary stitching on the headrests. Power driver’s seat controls allow the seat to move freely in a most directions, though it is said to grind in two others. The headliner is reported to be delaminating in some areas.
Equipment includes air conditioning, cruise control, and an optional Delco Bose sound system. Lighting and gauges are said to be working as they should, and the digital odometer shows just over 22k miles. The left power window switch was replaced in August 2017 along with a rear Bose speaker, while a new reverse light switch was installed in November 2016.
The 5.7-liter LT5 V8 is mated to a 6-speed manual transmission and was good for 375 horsepower when new. This ZR-1 has been modified with a Lingenfelter rear differential with a 4.09:1 ratio. Recent maintenance included fresh Redline oil in the gearbox and differential in October 2017 as well as a new coolant temperature sensor and EBC Yellowstuff brake pads the previous August. Spark plugs were replaced in January 2016.
New yellow KONI Sport shocks were installed in August 2017. There is no servo control on the suspension because of the new shocks, and the brake service lamp was removed to silence the servo-control warning and to avoid power loss as recommended by the seller’s mechanic. The power brake booster was replaced in May 2010.
Underbody photos document the condition of the undercarriage and suspension components. The lower ball joints are said to be worn, with the left being measured at 1/32” and the right being negative. The left rear wheel bearing is slightly loose.
An accident-free Carfax confirms California ownership history from new and corroborates mileage with 14 odometer readings from August 1995 to October 2016, when the car passed its last California smog check. Five owners are shown, with the seller noting that two were his mother and father. Included service records reportedly date to November 1993.
|Winning Bid||USD $22,000 by FortLangleyBC|
|Auction Ended||April 13, 2018 at 12:30PM PT|
|14,769 views | 544 watchers|


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Your quest for the finest WordPress themes will present you to Elegant Themes in some stage of your search. The developer has actually been in business for eight years and has vocalized around eighty seven themes till date. In a reasonably short time period, the company has actually managed to encourage almost 5 hundred thousand users to download and use their themes and plug-ins. Inning Accordance With Elegant Themes, they have 437,821 clients today. The designer declares to have the supreme WordPress toolkit for organizations and web designers. Without diving into every claim of the designer, one can safely state that Elegant Themes is a brand to reckon on the planet of WordPress themes and plug-ins. It has among the most active communities of users and the items & services are definitely trusted. The Elegant Themes blog site is also handy. It is a knowledgebase that addresses practically every inquiry you might have, either prior to signing up with for any of its themes & plug-ins or after. Elegant Themes Upgrade
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About two months ago, I twisted my knee and have been limping around with a cane ever since. My original diagnosis was bone spurs on my kneecap and it looked like knee surgery was in the near future. After a visit to an orthopedist, I got the good news that there were no bone spurs and that all I needed was some physical therapy. Praise The Lord!
In my earlier days, I used to walk down into the Tuolumne canyon to find great wilderness fishing. The Preston Falls trail from Early Intake was a great spot. and only a 4 mile walk in and then 4 miles back out. Since I prefer to fish as I’m wading upstream, I’m fighting the current the entire day which can get pretty exhausting. Other great spots were the Drew Ridge trail leading upstream several miles above Lumsdens Bridge. Another great spot was the Jawbone Trail which dropped about 2,000 feet down into the Tuolumne about halfway between Lumsdens and the Cherry Creek confluence; again at days end when I was already tuckered out, I had to face that grueling 2,000 foot climb back to my truck. =Such hikes provided some great fishing, but are definitely a younger person’s game. I don’t think I could survive one of those Herculean treks anymore. I may be a fanatical angler, but I’m not suicidal.
=Fortunately, over the last 40 years or so a cadre of professional raft companies has sprung up to help out old codgers like me. You can get on a raft at Meral’s Pool, and float downstream from Lumsdens Bridge, and take a 2 or 3 day trip all the way down to Wards Ferry at the beginning of Lake Don Pedro. Professionally guided raft trips down the Tuolumne make the river accessible to old folks like me and folks with physical disabilities that otherwise couldn’t experience the wonders of a mighty Sierra river.
The highlight of any trip down the Tuolumne is going over Clavey Falls. The first time I saw Clavey Falls. I was amazed, the entire river dropped off rock ledges into a maelstrom of water that looked much like the pictures I had seen of Niagara Falls. As they approach the falls the raft guides pull their rafts over and walk along the river to determine the best way to run a raft over them at that particular flow. I chickened out and told the rafting guide that there was no way I was going over those falls in a raft! So I climbed out and with my ever present fly rod began to fish my way downstream to meet the rafters below the falls. It wasn’t too long before I saw all kinds of gear floating in the river, including my aluminum rod case! The raft I had been on had flipped over and dumped all the passengers and gear into the cascade!
On subsequent trips at different flows I finally worked up the courage to actually go over Clavey Falls in a raft. It’s a heart stopping ride sort of like a roller coaster combined with a Maytag washer. It’s not for the faint of heart, but as near as I can tell no raft passenger has ever been killed there. You will definitely get drenched & you may go for a swim in icy waters, but it will be an experience you’ll never forget,
Somewhere in time, the river rafting experts came up with a rating system that ranks raft trips by degree of difficulty, a class I float trip is basically like floating in your bathtub with a slight current to keep you moving. No excitement, just peaceful relaxation while you observe the fish & wildlife. As the rating class numbers get higher, the ride gets more exciting. A class III river is about the most that amateurs should try by themselves, while a class IV or Class V raft trip is a white knuckle, white water, roller coaster. Depending on water flows, the upper Tuolumne ranks as a Class III, IV, or even a Class V raft trip. If the Tuolumne doesn’t get your adrenalin flowing, you probably died some time ago.
You don’t have to be an angler to enjoy the wonders of the Tuolumne, but it’s a great way for old codgers like me to get into some great fishing, Reputable raft companies that I’ve known include: Sierra Mac Adventures, Oars, and Echo. Look them up under whitewater rafting –Tuolumne River. You’ll be glad you did!
Until Next Week,

domain: geography