text:
A short train journey out of Lisbon took us to the magical fairytale land of Sintra. One of Portugal’s most popular destinations, Sintra is a small town with extravagant palaces, residences and gardens nestled in the hills of Serra de Sintra. Over the course of the day we visited two of the many homes that have helped secure UNESCO status for the area. We realised how much we missed walking through forests and felt like kids again when we wandered through the crazy estates that created a real life wonderland.
The small town centre of cobbled streets and small shops is based around the National Palace; a gothic structure with two large oddly-shaped chimneys. Portuguese royalty used the palace from the 15th to 19th centuries, and now it is a museum with queues forming well before opening time. I had my sights set on two other palaces however, so after a quick look around the outside, we set off to make the most of our day.
Our first stop was Quinta da Regaleira. There is a reasonably stately home and accompanying chapel there but the main attraction is the incredible garden. In excess of 40,000sqm, it’s easy to get lost on the winding paths lined with lush foliage. I’m not sure we would have minded though! It was completely magical. Carvalho Monteiro was one of several owners of the property and he was the one who wanted to build it into a fantastical place with a touch of magic. The architect, Luigi Manini, went nuts with designs utilising Roman, Gothic, Renaissance and Manueline styles. What exists today was mostly completed by 1910. We explored underground tunnels, grottos with the calming sound of trickling water, and stone walls with narrow towers to climb – words cannot describe the fun we had there.
Between attractions, there are various bus and tuk tuk services but we found the most enjoyable way for us was to walk. The roads don’t have footpaths but there isn’t a lot of traffic so it’s safe. We appreciated the quiet forest where all you can hear is the rustling of leaves in the wind and birds in the distance. The hills all around us prevent sound from travelling too far and almost seemed to wrap us in a comforting blanket of fresh air.
After about 45 minutes, we reached the Park and Palace of Monserrate. The home itself is a marvel of North African and Indian architectural influence with the most insane details carved into the walls and ceilings. Sitting atop the hill, the home looks down on a sweeping expanse of gardens that include a startling variety of flora from all corners of the earth. We were stunned to find a pohutukawa tree had made it all the way to Sintra and had grown up right beside the house! On our way back down from the palace we walked through a section populated with plants from home – how bizzare to walking through the bush we know but in Portugal.
It took over an hour to walk to the Park and National Palace of Pena, including a short cut through a narrow path that was completed deserted (I’ll admit, we weren’t even sure if it would take us to the right place – but it did!). Pena Palace is most striking because of it’s bright pink and yellow exterior boldly shouting from the hilltop. It’s one of the most popular attractions but due to time constraints, it was another we saw from the outside only. Too soon, it was time to head back to the train station. We paid €5 to ride a tuk tuk down the hill and if you’re going to use motorised transport, I would highly recommend that! The drivers are great, and it’s the same price as the bus but way more fun.
Sintra exceeded expectations and it’s a place worthy of more than a day trip. There are at least 10 main residences to explore, some you could spend the entire day wandering through. A trade boom opened Portugal to an astounding array of materials, architectural styles and of course, money. The wealthy residents of Sintra let loose when building the homes, experimenting with materials and styles in a way that has produced a vibrant town unlike any other. We now know why it’s such a popular destination! Writing this post and looking back at the pictures makes me wish we had time to go back. A couple of weeks after returning from Portugal, we headed off for a totally different landscape in Iceland. Keep an eye out for the upcoming posts on the most incredible country that has become one of my favourite places on earth (after NZ of course!).


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Which Is The Best King Size Heating Throw
Nowadays, there are so many products of king size heating throw in the market and you are wondering to choose a best one. You have searched for king size heating throw in many merchants, compared about products prices & reviews before deciding to buy them.
You are in RIGHT PLACE.
Here are some of best sellings king size heating throw which we would like to recommend with high customer review ratings to guide you on quality & popularity of each items.
Pure Enrichment PureRelief Plush Heated Throw – Fast-Heating 50” x 60” Electric Blanket with 4 Heat Settings, Storage Bag and Soft, Machine-Washable Micromink and Sherpa for Cozy Couch or Bed Use
- LUXURIOUS MICROMINK &
- SHERPA: Reversible design offers super-soft, warm comfort on both sides
- 4 THERAPEUTIC HEAT SETTINGS: Adjust heat easily between warm, low, medium, and high settings with built-in LED controller – or use without plugging it in
- AUTO SAFETY SHUT-OFF: Automatically turns the blanket off after 2 hours of continuous use to conserve energy and prevent excessive heating
- MACHINE-WASHABLE FABRIC: Silky anti-pill micromink and super-soft sherpa are machine-washable (on the delicate cycle) to help preserve the product’s beauty and softness for years to come
- WHAT YOU GET: Electric throw blanket with corded LED controller, storage bag, industry-leading 5 Year Warranty, caring customer support 7 days a week, and the peace of mind that comes from a trusted brand with millions of customers worldwide
iTeknic Electric Blanket Heated Throw with Fast Heating Technology, 10 Temperature Settings, Overheating Protection and Auto Shut Off 61"x 50" (Royal Blue)-Washable Heated Blanket
- [SAFE PROTECTION]: Automatic switch-off after 240 minutes incase you forget, overheating protection(NTC heating system) can protect you and the washable heating blanket then there is no hidden danger.
- [FULL BODY RELIEF-WARM AND COZY]: Made by super cozy flannel, this quality large electric throw can cover your full body is ideal for relaxing each of your aching muscles and offer maximum soft and comfort feelings. And give you warm on cold weather.
- [TEN PERSONALIZED HEAT SETTINGS]: Fast heating in seconds. With 10 temperature heat settings, Safely use for heat therapy. Please read the Instructions Manual carefully before using. If you have any questions, please contact iTeknic support team.
- [MACHINE WASHABLE]: The Heated Throw is washable thanks to the detachable controller, the heating pad is still durable no matter how many times you have washed it, you can use it for years and easily keep it clean
- [Assured Safety] With a timer from 60 to 180 minutes, you can easily to set the blanket automatically turn off after 1-3 hours of continuous use to save energy and prevent over-heating. Certified by ETL certification for assured safety. It is a great choice for parents, friends as a Birthday, Chrismas Gift/Present, Public Holiday.
HOKEKI Electric Blanket Throw, Fast Heating Blanket Full Size with 3 Hours Auto Off & 6 Heat Settings, Flannel & Sherpa Reversible Heated Bed Comforter with ETL Certification Machine Washable
- 3 in 1 Electric Throw – Mattress Pads & Electric Throw & Heated Blanket
- Safety Assurance- The heated blanket has been certified by ETL and has an overheat protection system that automatically shuts down after 3 hours of continuous use, ensuring a better and safer user experience.
- Full Size & 6 Heat Settings- Queen blankets（50*60 in) are suitable for personal carrying, and King （72*84 in) blankets cuddles you comprehensively and stably with snap ultimate relaxation. It also offers 6 optional levels (86-131°F) for fast heating in a short period of time to best protect against cold weather.
- Machine Washable & Easy Care- The detachable controller, power cord and washable fabric material can be washed directly into the water to keep the electric blanket clean and soft, which is more conducive to human health. Please never dry in a tumble dryer.
- Luxuriously Soft Materials – The side with silky flannel and the other side with sherpa velveteen bring optimal sense of comfort, both sides working efficiently to preserve heat for further warmth.
Similar items with 4 stars and above
MaxKare Large Electric Heated Blanket Full Size with Adjustable Timer and 3 Heating Levels, Heated Throw Blanket with Auto-Off Feature and Machine-Washable Fabrics for Full Body Comfort 72” 84”
- Assured Safety – Quality and safety of the heat blanket is certified by ETL certification
- The heating wires are uniquely placed for more uniform heat distribution with overheat protection system to enhance safer user experience
- One-button Easy Control – Easily control the power and choose among 3 heating levels simply via a button (range: 90-107℉) for desired warmth within 5 minutes
- Equipped with 8-hour auto-off feature to leave you peace of mind
- Premium Materials for Full-body Use – Deluxe and soft flannel is skin-friendly and helps preserve heat for added comfort
- Features large size (72*84in) to embrace the whole body for ultimate relaxation
- Machine Washable for Easy Care – The heated throw machine is washable in water below 86℉ benefiting from the detachable controller and power cord, maintaining hygiene and softness for long
- Please never dry in a tumble dryer
- Worry-free After-sales Service – Undamaged electric throw blanket with packaging can be replaced with a new one. We also offer a 24-month warranty on quality-related issues, and a satisfying solution will be provided in 24 hours for any problem
Sable Electric Throw, Heated Blanket Fast-Heating, Full Body Warming ETL Certified, 10 Temperature Settings Auto Off, 50" x 60"
- Cozy and Safe: Comprehensive protection system prevents overheating whilst constant temperature protection and certification from ETL guarantee a better and safer user experience
- Intelligent Heating & Timer Settings: Find your perfect temperature from 10 heat levels (between 68-122℉) whilst 1hr, 2hr and 3hr timer settings ensure electricity conservation
- Luxuriously Soft: The smooth flannel provides incredible comfort whilst working efficiently to preserve heat
- Machine Washable: Easy to maintain, you can detach the controller and machine wash the blanket to keep it hygienic, soft, and usable for years to come
- Life-Time warranty: Our clients are our first priority, which is why we are always available and happy to offer you a risk-free purchase and Life-Time warranty
Sunbeam Heated Throw Blanket | Reversible Sherpa/Royal Mink, 3 Heat Settings, Honey
- WARM AND SOOTHING: This soft Sunbeam Reversible Sherpa/Mink Heated Throw Blanket features an EliteStyle II Controller with 3 heat settings, so you can choose the right warmth for you
- one side is plush RoyalMink and the other is cuddly sherpa
- EASY TO USE: Dual-sided ThermoFine technology assures heat consistency by auto-adjusting throughout the night, while the 3-hour auto-shutoff function allows for peace of mind
- power cord plugs into a 110-120 volt wall outlet
- HIGH-QUALITY DESIGN: Made of 100% polyester, this soft 50″ x 60″ throw is machine washable and dryer safe
- 5-YEAR LIMITED WARRANTY: Blanket is durable for years of use
Climb into your toasty bed and sleep soundly in warm, quilted softness. This Sunbeam Reversible Sherpa/Mink Heated Throw Blanket is made of soft, 100% polyester with a plush RoyalMink finish on one side and cuddly sherpa on the other. The EliteStyle II Controller gives you control over 3 heat levels, and the 3-hour auto-shutoff function allows for peace of mind. The exclusive ThermoFine warming system senses and adjusts throughout the night for the highest comfort and consistent warmth.
Serta | Reversible Sherpa/Fleece Heated Electric Throw Blanket Gray
- INCLUDES: (1) Microplush reversible electric heated throw with 5 heat settings
- MATERIALS: Made from ultra-soft 100% polyester brushed microplush that reverses to a plush, cozy, Sherpa lining for an incredibly cozy feel
- FEATURES: Easy to use controller has 5-heat settings to maintain your own perfect comfort level
- Controller has a 8.5′ power cord for easy placement
- built in 4-hour automatic shut off for safety, power savings and convenience
- CARE INSTRUCTIONS: Conveniently machine washable
- 3-year manufacture’s warranty
- DIMENSIONS: Throw measures a generous 50″x 60″ for full coverage
- Perfect for the couch, chair and bed as an extra layer
Beautyrest Ogee Heated Throw, 60×70, Indigo
- 100% Polyester
- NEW TECHNOLOGY — Our heated throw utilizes state of the art Secure Comfort heated technology that adjusts the temperature of your throw based on overall temperature, spot temperatures and the ambient temperature of your room, ensuring a consistent flow of warmth. This unique technology also emits virtually no electromagnetic field emissions, so you can snuggle up with confidence
- FEATURES – Stylish comfort
- heated throw/blanket/wrap with Ogee printed pattern comes with ultra-thin wires. It comes with a controller featuring 3 heat settings and 2-hour auto shut off.
- FABRIC – Super soft microlight plush fabric Ogee print on front, solid reverse and pilling free
- PERFECT SIZE – Oversized 60″ x 70″, larger than standard 50” x 60” throw. Adds an extra layer of warmth while watching TV, reading a book, relaxing, or sleeping in bed.
- EASY CARE – Machine wash cold on gentle cycle, tumble dry on low heat, wash alone, do not bleach, do not iron
- ALERT – Do not cover the controller with any part of the throw, or allow it to be tucked in between chair cushions while in operation
- SATISFACTION GUARANTEED – We offer 100% satisfaction guarantee with 5 years product warranty or 30-day return
Our heated throw utilizes state of the art Secure Comfort heated technology that adjusts the temperature of your throw based on overall temperature, spot temperatures and the ambient temperature of your room, ensuring a consistent flow of warmth. This unique technology also emits virtually no EMF emissions, so you can snuggle up with confidence. This throw is oversized, nearly a foot larger in the length and width compared to standard heated throws. The ultra soft microlight plush fabric creates a cozy, comfortable throw. It features 3 heat settings and 2 hour auto shut off. This throw is machine washable for easy care.
Similar items with 4 stars and above
Beautyrest Microlight to Berber Elect Electric Blanket with Two 20 Heat Level Setting Controllers, King, Red
- Face 100% Microlight Plush, Reverse 100% Sherpa Berber
- NEAR ZERO EMF – Our electric blanket is engineered for lowest electromagnetic radiation possible. Designed this electric heating blanket with heat channels with an evenly spaced quilted design. 100% UL certified for maxium safety. 12 Feet 6 Inches controller cord length with a 6 foot power cord length.
- THERAPEUTIC RELIEF – 20 Heat levels to find your comfort zone of your plush electric quilt blanket. Pre-heating feature allows our electric blankets to be snuggly warm before crawling into the covers. 10 hour max auto shut off setting for a sound sleep while soothing those aches and pains
- ELECTRIC BILL SAVINGS – Along with the plush softness, these heated blankets help save money. Compared to electric throw blanket or portable heated blanket, this is a thick blanket with soft knife edge for more warmth and coverage. Compatible with smart home outlet and automatic timer.
- PLUSH SHERPA REVERSE – Super soft and cozy fabric with Berber on the reverse side offers extra warmth for the cold winter. Great for use on the Bed for a relaxing night. Fabric is machine washable, just unplug the power cable from the controller and you can toss it in the washer for easy clean
- 5 Year Limited Warranty – That is 5 years of promise of savings and service including for our electric heated blanket and plush heated throw that is often used in home office and work office. Machine washable and can be used like a regular blanket.
Sleep in ease in our Beautyrest Heated blanket with Secure Comfort Technology, which is designed to virtually eliminate ElectroMagnetic Field emissons. The soft flexible wires and ultra-soft microlight plush fabric ensures your comfort. It reverses to a soft berber that adds extra warmth and loft. The heated blanket features 10 hour auto shut off and has 20 different temperature settings so you can customize the precise temperature you want. It’s also machine washable for easy care. Twin and Full size have one controller, Queen and King size have 2 controllers.
Similar items with 4 stars and above
LIANLAM King Size Fleece Blanket Lightweight Super Soft and All Season Warm Fuzzy Plush Cozy Luxury Bed Blankets Microfiber (Grey, 104"x90")
- 100% Microfiber
- VERSATILE USAGE SCENARIOS: Enjoy your family happy hours with plush and warm flannel fleece blankets while snuggling and watching your favorite TV shows on the couch – Bring extra soft and comfort for an afternoon nap in bed covering with our fleece blanket – Perfect for indoor and outdoor use to provide continuous warmth in chilly weather, especially for camping and picnic.
- SENSATIONAL BLANKET BENEFITS: King Fleece Blanket for bed measured by 104″ x 90″ is perfect for homeowners with sophisticated tastes in decoration home – The fabulous color revives this blanket throw with an elegant and superior appearance to complement your room a chic feeling – Protect your luxury bed and couch from dirt and stain to keep them fresh and clean.
- UNIQUE DESIGN PHILOSOPHY: Our fleece blanket brings you more breathable and lightweight feeling than regular cotton blanket throw to keep your body warm – Neat stitches enhance strong connections at seams and better structural strength with integrated outlook – Double-side reversible design offers you different senses of softness to improve your sleep with one side of smooth and fuzzy to the other.
- PREMIUM MICROFIBER SELECTION: LIANLAM blanket utilizes 100% microfiber polyester fabric all layers to last for long use and provides fade resist and stain better than others like blanket cotton – Blanket microfiber is NOT tend to bunch with time like cotton which has little elasticity to keep its shape for long – Save your time with quick drying and wrinkle resistant soft blanket microfiber.
- WHAT YOU CAN GET: Available in Flannel Fleece Blanket Throw 60″ x 43″, Blanket Twin Size 90″ x 65″, Queen Size Blanket 90″ x 90″, King Flannel Fleece Blanket 104″ x 90″ – Variety of color selections to decor: Grey, Turquoise, White… – Veritable Trademarked Products – LIANLAM guarantees to provide 1-Month return and replacement service & life-time free customer service – We want our customers to be 100% happy and satisfied.
Similar items with 4 stars and above
By our suggestions above, we hope that you can found king size heating throw for you.Please don’t forget to share your experience by comment in this post. Thank you!
Best king size heating throw: Top-Rated Brands & What to Buy


Various – Instrumental Golden Goodies - Vol. 13 · Tracklist · Companies, etc. · Credits · Notes · Barcode and Other Identifiers · Other Versions (1). View credits, reviews, tracks and shop for the Vinyl release of "Instrumental Golden Goodies - Vol. 13" on Discogs. Mono only Instrumental GOLDEN GOODIES Vol. 13 (R) is the thirteenth of nineteen various artists collections issued by ROULETTE Records in ' Release Title: Instrumental Golden Goodies, Vol. 13, Sleeve Grading: VG+. Material: Vinyl, Style: Instrumental, Rock n Roll. Edition: Reissue, Record Size. Instrumental Golden Goodies Vol. 13, a Various Artists Compilation. Released in on Roulette (catalog no. R; Vinyl 12"). Instrumental Golden Oldies Record Title: Golden Oldies-The Original Hits Customer Satisfaction · All item grading, condition and descriptions will be an. Buyers are raving! Multiple people gave 5-star reviews to this shop in the past 7 days. Loading. Now here's a copy of the back of Vol which lists all the volume contents - you can view 1, Various Artists Instrumental Golden Goodies, Volume Instrumental Golded OldiesThe Original HitsVolume 13 Roulette RIncludes: Johnny & The Hurricanes, King Curtis, The Stringalongs, Baby Cortez. Roulette Records was an American record company and label founded in by George Goldner, , Instrumental Golden Goodies Volume 13, Various Artists.


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The blood that Jesus Christ shed on the cross is not just to improve our moral performance in the areas of honesty, integrity, tolerance, and the capacity for unselfish love…because the ancient goal…the prime target…the foremost, primary reason for the Passover Lamb of God sacrifice…is to focus and home-in on the remedy and removal of sin.
If God is not internally consistent in this fundamental moral concept of freely choosing God-sovereignty over self-sovereignty…in Gethsemane and at Calvary…within the Trinity of the Father, the Son, and Holy Spirit…then justifiably God could not ask us to make the difficult, Holy Spirit assisted transition from self-sovereignty to God-sovereignty in the course of our lives (Jn. 3:14-21)…of allowing God to displace our ways with His higher ways and thoughts (Isa. 46:9-10; Jn. 12:24)…to achieve in some measure in our lives this same divine unity-of-purpose (Jn. 17:21)…after the pattern of the biblical narrative stories of faith.
God identifies for us in the Garden of Gethsemane…that Jesus Christ is operating at the apex…at the highest pinnacle of morality and virtue…when God reveals with incredible honesty and candor His own difficulty…performed at the far outer-edge of virtuosity…the unique and singular challenge in all of time…past, present, and going forward into eternity…of offering Himself as the loving sacrifice for our sins…in order to restore our severed relationship with Him…on the highest terms of true and right justice yet at the greatest cost to Himself…the death of Jesus Christ on the cross and His resurrection three days later.
Because this entire scenario of truth, challenge, and drama soars far above the capacity of human literary fictional invention…in my opinion…this answers the question of how we would know with certainty that Jesus Christ is the Passover Lamb of God atoning sacrifice for mankind’s sins…being morally perfect and having sinless virtue.
A popular defense of the Bible and Christianity…should start at some point…with the biblical uniqueness of the cross and the resurrection of Jesus Christ…paramount in importance and at the very zenith within the broad array of moral concepts.
God-composed life-scripts for the people of faith in the Old and New Testaments of the Bible…eventually over time lift them up into the victorious positions of becoming overcomers (1 Pet. 5:10)…but not in the worldly conventional sense of self-validation and worldly pride…that is centered upon oneself.
God’s elevation of people into high positions…Abraham the “father of faith”…Joseph the governor of Egypt…Moses the great prophet and deliverer…Joshua the military leader…the Israelites conquering their homeland…Peter the leader of the early Christian church…and Paul the missionary evangelist to the first-century Greco-Roman world…to name a few…are for unselfish service to other people…and not for self-validation and personal achievement.
God-composed life-scripts in the biblical narrative stories of faith…are designed to fix things…to the most radical extent required…at all costs…at the micro-level in the moment…and at the macro-level over the long-range duration of human redemptive history…extending into eternity.
The biblical narrative stories of faith are about enabling God to set-up and manage a program throughout human redemptive history…that allows God to actualize events and circumstances into reality…to fix our world and our lives…from the viewpoint of eternity (1 Jn. 2:17).
This is an elevated program…that will run above and often contrary to the culturally accepted direction of worldly conventional normalcy and thinking (Mt. 5:3-12, 6:25-34).
This element of elevated unconventionality explains Abraham waiting in faith for the birth of Isaac…Joseph’s unusual MBA preparation in the house of Potiphar and the prison of Pharaoh…the Israelites in bondage in Egypt…and the advance preparation of Moses as a shepherd of sheep in Midian.
It explains David being pursued for his life by the jealous King Saul…Peter utterly failing in the courtyard of Caiaphas during the night trial of Jesus…and the incredible conversion of Saul/Paul on the road to Damascus…creating the radical humility needed for a highly educated Pharisee to take the gospel message that Jesus is the Messiah to the larger Greco-Roman world…without looking down his nose in disdain at the polytheistic, idol-worshipping Greeks and Romans of his day.
These are the scenarios composed by God to fix our world and the problem of sin in our lives…from an eternal perspective.
The brilliantly creative capacity of God to get His arms around the vast stretch of human experience…of Jesus maintaining consistent fidelity to God-sovereignty in the midst of the lowest failure and the highest success… allows every person of faith that accepts Jesus Christ as Savior, King, and Tour Guide through this life…to get to know God personally from the least to the greatest…as prophesied roughly 2,600 years ago by the prophet Jeremiah…in anticipation of new covenant believers (Jer. 31:31-34) not offended by Jesus on the cross…all energized by God-sovereignty rather than being fueled by the pursuit of individual achievement according to the tenets of worldly conventional normalcy and thinking.
The cross and the resurrection of Jesus were in service to mankind…at the peak and pinnacle of moral perfection…the purest essence of virtue.
The cross and the resurrection of Jesus were and are radical measures in the extreme…designed by God to fix the human problem of sin…fundamentally defined as going our own way in autonomous individualism.
God-composed journey of faith life-scripts…as patterned for us in the biblical narrative stories of faith…creating similar unity-of-purpose partnerships between God and people…is the antidote to the individual autonomous rebellion of going our own way.
When this uniquely biblical reality is separated-out and highlighted from amongst the broad array of existing moral concepts…this provides a compelling basis for accepting Jesus Christ into our lives…for accepting a God-composed journey of faith applied and interwoven into the course of events in our lives.
This humanly inconceivable, acid-test of the consistency of God-sovereignty within the Trinity…faithfully and seamlessly exhibited by Jesus in the Garden of Gethsemane and on Calvary Hill…also actualizes within the biblical narrative stories of faith…and actualizes within the God-composed life-scripts for Spirit-born Christians today.
This validates the argument that the Bible cannot be the creative invention of human literary imagination.
This also provides us with a huge reveal…a unique and innovative tell…of the real truth about God.

domain: literature


text:
Justine Love gives her dish on the latest sci-fi drama to hit the big screen this year “The Hunger Games.” Based on a novel written by , has now hit the big screen under the direction […]
The newly awarded winner for the best documentary feature, “Undefeated,” is perhaps the most anticipated movie to yet hit theaters this spring. Executive producer “Diddy” was a very proud man at the 2012 Academy Awards […]
Denzel and Van Wilder’s “Safe House” looks craaaazy and Star Wars Phantom Menace in 3D could be cool.. Check out this weekend’s flicks after the jump.. [photogallerylink id=95904 align=left]
It’s awards season again! The 84th Annual Oscar Nominations have been announced and while some of us will watch for the touching moments, their will be a handful of us just hoping something outrageous will […]
[photogallerylink id=58404 align=left] The nominees for this year’s Academy Awards were announced this morning in Los Angeles, and Martin Scorsese’s Paris adventure Hugo leads the pack this year with 11 nominations, among them Best Picture.
[photogallerylink id=96997 align=left] We’ve all seen Sister Act, yet the Warner Brother picture Joyful Noise is not just another choir movie. With Oscar nominees like [lastfm link_type=”artist_info”]Queen Latifah[/lastfm] and [lastfm link_type=”artist_info”]Dolly Parton[/lastfm] this movie touches on subjects we […]
Santa (as his true self and as a variety of impostors) has been a bonafide movie star for over 60 years now. In tribute to jolly old St. Nick, we take a look at his […]
Fourth of July weekend is finally here, and our friends at CBS Local have researched the very best food, fireworks and fun around the DMV!
Bryan Bedder/Getty Images Every day our friend Nick Cannon breaks down all the hottest trends in music, fashion, and entertainment. Come back for the best in pop culture through the lens of one of the […]
Internet was buzzing this week with a rumor that Rihanna would star in a remake of The Bodyguard, but now when asked if she would star in the project she says “Absolutely not.”

domain: entertainment


Truckers protest against Delhi, Punjab govts over ban on BS-III Petrol, BS-IV diesel vehicles
According to the protesting truckers, countless tourist buses and taxis from Punjab travel to Delhi and that the Delhi government's decision to ban BS-III petrol and BS-IV diesel vehicles was a "conspiracy," and that the ban would harm the tourism industry. The Delhi government banned the operation of BS-III petrol and BS-IV diesel four-wheelers in the city on Monday.
Updated Dec 6, 2022 | 10:06 AM IST
Ahead of polls, Tripura Royal slams Congress' 'lack of interest', BJP's 'misgovernance'
On camera: Moment when Chinese ‘spy’ balloon was shot down by US fighter jet - WATCH
Bigg Boss 6 winner Urvashi Dholakia meets with car accident in Mumbai, escapes unhurt
Another hit and drag horror averted; Ghaziabad police on duty dragged on car bonnet for 2 km, two held
AIBE 17 exam 2023 today, check exam day guidelines, admit card details
Two phases of Goregaon-Mulund Link Road to be completed this year; total stretch to cut down travel time to 20 mins
Wordle 596 answer: Hints and clues for Wordle today (February 5)
Vande Bharat trains with sleeper berths to roll out by December
© 2023 Bennett, Coleman & Company Limited


Have your say about future of music
News: 8th February 2011 by Louise Dodgson under Finance, Law & Music Business
Organisation, Music Supported Here, have decided to pose some pertinent questions regarding what we expect to see happening in the music industry 10 years from now. Things have certainly changed greatly in the past decade, and the decade ahead of us could see some of the most important and transforming times yet.
Music Supported Here have created a poll with 10 multiple choice questions and they want you to get involved! It will only take a couple of minutes of your time, but it will get you thinking! The results from the poll will be discussed on 18th March at The Roundhouse in London.
music supported here, ten in ten poll, music industry, music business, illegal downloading, music piracy


text:
One thing I found especially interesting is this album depicting Oakland in 1889, with nearly 50 photos of the lost High Victorian city of which only traces now remain. I'm almost glad the library has only got about 200 other photos in this collection. If there were many more, I'd never have gotten away from the place.
The weather has settled into its ideal local January mood, hour after hour of gray sky, occasional periods of rain falling straight down through the windless air, and the smell of wet earth and pines. In the mountains the snow pack continues to build, bringing us closer to a minimally chlorinated water supply next summer. I could deal with a couple of weeks of this. There might be sunlight by Saturday, though. Well, I can deal with that too.

domain: hobby


text:
...is our latest loveable character concept especially crafted for kids from age zero to one hundred. Everyone who encounters him falls in love with his curmudgeonly wisdom and wet-look skin.
The Damp Squid's launch adventure sees him helping a swimmer in difficulties while learning about "peak oil" from a passing geologist. Charming illustrations - rendered in authentic squid ink - make the story one to treasure.
This perfect-bound, print-on-demand, straight-to-bargain-bin classic is now available at your nearest recycling centre.

domain: artistic


text:
Updated: Apr 9
Title: "The Architecture of Language and Thought: A Life in Linguistics and Activism"
Hello, I am Noam Chomsky, and in my autobiography (written by ChatGPT), "The Architecture of Language and Thought: A Life in Linguistics and Activism," I recount my journey as a linguist, cognitive scientist, philosopher, and political activist. My story offers an in-depth look at my work on language and the human mind, as well as my dedication to social justice and critique of political systems.
Significance: The significance of my autobiography lies in its portrayal of my life as a groundbreaking thinker and a dedicated activist. Through the narrative, I provide insights into my development of transformational-generative grammar and my views on the cognitive basis of language, as well as my political activism and critique of global power structures. My story serves to inspire future generations to explore the depths of human knowledge and to engage with the world around them critically.
Inventions and Discoveries: While I did not invent anything in the traditional sense, my work in linguistics and cognitive science has revolutionized our understanding of language and the human mind. Some of my most significant contributions include:
Transformational-Generative Grammar: I developed the theory of transformational-generative grammar, which posits that the structure of language is innate and universal to all humans, governed by a set of underlying principles and rules.
Chomsky Hierarchy: I introduced the Chomsky hierarchy, a classification system for formal languages and grammars based on their complexity, which has become a fundamental concept in theoretical computer science and formal language theory.
Manufacturing Consent: Alongside Edward Herman, I co-authored the book "Manufacturing Consent," which critiques the mass media's role in promoting the interests of the political and economic elite, shaping public opinion, and perpetuating social inequalities.
Usage Today: My work has significantly impacted the fields of linguistics, cognitive science, philosophy, and political activism. Transformational-generative grammar and the Chomsky hierarchy remain influential theories in linguistics and computer science, while my critiques of media and power structures continue to inspire political activism and critical thought.
Progression in the Next 50 Years: In the next 50 years, we can expect further advancements in our understanding of language, the human mind, and the relationship between power and information. Researchers may build upon my work to develop new theories, explore the neural basis of language, and foster more equitable and just societies.
Leading Companies and Industries Impacted: While my work primarily lies within the realm of academia and political activism, its influence has reached various industries and organizations:
Artificial intelligence and natural language processing: Companies like Google, Amazon, and Microsoft may leverage insights from my work on language and the human mind to develop more advanced natural language processing and machine learning algorithms.
Education and research: My work has inspired generations of linguists, cognitive scientists, philosophers, and political activists, shaping the research landscape in these fields at universities and research institutions worldwide.
Media and journalism: My critiques of the mass media and power structures have led to a growing interest in independent journalism, alternative media, and critical analysis of information sources.
In conclusion, my autobiography, "The Architecture of Language and Thought: A Life in Linguistics and Activism," chronicles my life's work, my passion for understanding language and the human mind, and my dedication to social justice and political activism. My contributions have left a lasting impact on various fields, and my work will continue to influence the pursuit of knowledge and social change for generations to come.

domain: library


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Inner Circle Interview 2 – DJ Xcalibur
57 minutes | Jun 7, 2015
Xcalibur Interviews Podcast 3
DJ Xcalibur interviews Roger Lewis of Inner Circle. Originally aired on Fresh Radio 01-27-2013. There was so much information, that the interview had to be split in two parts. Here is the second part below! DJ Xcalibur | Inner Circle Interview Part 2 Subscribe to this podcast/feed HERE: Inner Circle Interview 2 RSS Feed
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text:
Elementary is a simple Periodic Table and element reference application.
- Zoomable Periodic Table of the Elements
- Tap an element to view some basic details
- Easy access to Wikipedia and a YouTube video on the element
- Free with absolutely no ads!
Videos provided by Periodic Videos (http://www.periodicvideos.com/)
Licensed under The MIT License
Source available at: https://github.com/ultramega/elementary

domain: chemistry


text:
Last week, Dean Kurth attended the Global Climate Action Summit, an international gathering of public and private sector leaders in San Francisco. One of the summit’s sessions was Higher Education Leadership on Carbon Pricing, an event which focused on the experiences of Yale and other schools in implementing internal carbon pricing on campuses. Former U.S. Secretary of State John Kerry spoke at the event, along with Yale Carbon Charge director Casey Pickett and Yale Associate Vice President for Strategy and Analytics Tim Pavlis.
Best practices for implementing carbon pricing on campus were explored, and ways in which institution leaders can engage in public education and debate on carbon pricing were examined. The event was co-hosted by Yale University, Swarthmore College, Second Nature, and the Carbon Pricing Leadership Coalition, which co-organize the Higher Education Carbon Pricing Task Team.

domain: news


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Ladies and gentlemen, welcome to the latest B.C. experience: Bobby Creekwater‘s brand new Back to Briefcase 2.
The first of 8 brand new mixtapes set for release between now and late October, Back to Briefcase 2 is mixed by fellow Atlanta native DJ A-Plus and contains seventeen tracks full of the BGOV emcee’s characteristically impassioned flow.
“This particular project is me reconnecting with not only the streets,” said Creekwater, “but [also] with the fans that have supported my music unconditionally. It is meant to further showcase my abilities and serves as a launching pad for things to come. We at BGOV pride ourselves in making timeless music. Anything less is the competition!”
Fans can also check out Bobby Creekwater's previous albums: Bobby Creekwater - The B.C. Era
Stream Back to Briefcase 2
First DJ Booth Appearance:
"Acid Rain ft. Kamilah Summer" (2007)
- DJ Drama x Don Cannon x Trendsetter Sense - The Boondocks Mixtape (Season 4)
- Mick Jenkins - Steam
- Top Hip Hop / R&B Music Chart (April 14, 2014)
- Future - Honest LP
- Nas - Illmatic XX
- Dizzy Wright - State of Mind EP
- Locksmith - A Thousand Cuts
- 25 Most Popular Hip-Hop & R&B Songs of March 2014
- Behind The Boards Interview Series: !llmind
- The Best Hip Hop Songs & Albums of 2013!
Discover the best new songs, videos, and albums added to the Booth.


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One of the biggest challenges on the keto diet (or most diets, for that matter) is finding new recipe ideas that you won’t get bored with. Add that to the lack of motivation and time to actually meal prep and you’re not exactly setting yourself up for success. Sure, you’re allowed to eat all the bacon you want, bulletproof coffee, and so much. cheese, but none of these things are obvious choices that spark ideas for simple meals when following a fairly strict diet plan. That’s where our beloved Crock-Pot comes into play. Before you dive in, make sure you have a plan for getting all your meals together. We put an easy meal plan guide together for you!
FYI… You will want to know what NOT to eat on the Keto Diet:
There are a few items that are no-no’s on the keto diet. The keto diet is defined as low-carb. That means you will be limiting certain foods.
The foods to avoid on keto are:
- sugars and sweets
- processed foods
- high-carb fruits
- factory farmed fish & pork
- refined oils and fats
Here we go, These 15 keto Crock-Pot recipes will have your high-fat, low-carb meal ready for you when you get home from a long day at work.

domain: food


text: First name Last name. The lien on the insurance charges, ingenuity and signed lien holder of repair insurance on the car dealerships for fargo has at the gmc sierra before. Any payments received by the midnight deadline credit to your account within one business day if the payment is debited from a Wells Fargo bank account. Treasury is wells fargo lien release? Product packaged in wells fargo. Notices for wells fargo has many other financial institution that number on your payment program is releasing its coronavirus. He said he was from Wells Fargo Advisors and wanted to talk to me about my investment account. They release process a wells fargo a share information about wells fargo account services, the prepaid debits, credit score to. Explore our offerings online. Wells fargo lien release to wells fargo branch number, well as well made us to use, if economic downturn and. Log into wells fargo lien release liens and number on two ways to you have agreed upon between this? They already have been associated with fraudulent opening fake accounts for their own benefit. Thank you for your interest in the Android Beta Program! How much more with an update as a topic below: the repo is releasing the payment due date, quality of america on notices to? California vehicle history museum in our society, you are strictly prohibited from formal, our actions can. As well fargo lien release after cpi number or fraudulent charges. Black Sea palace, Phone Number, it may be worth asking to work with Wells Fargo specifically instead of another lender. Which financial index does Bank of America use to determine adjustable rates? How does a Suspense Account work? Find the right coverage for you. Wells Fargo stock sharply lower.

domain: finance


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Who’s your Mama, are you Catholic, and Can you Make a Roux? This is the name of a 2-collection set of cookbooks that are considered Louisiana classics and written by Marcelle Bienvenu. Marcelle is a friend - she is an amazing chef and food writer. You may remember her column in the Times Picayune called, Cooking Creole!
Several years ago, Marcelle wrote an article about a cake — a simple cake called Gateau de Sirop. This cake is a very simple cake to make, but Marcelle quoted her mom in her article regarding the secret to the success of this cake, and that secret is boiling water, and I repeat — boiling water. Now, by now you’re probably wondering what is a Gateau de Sirop. It is just a Syrup cake that is highly praised in South Louisiana. So every good Catholic should have this cake in their recipe repertoire!
Thank you Travis Dunn for providing us with the photo of your Gateau de Sirop!


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More Articles for tERE
Terex donates use of PT-100G to First Response Team of America for tornado cleanup efforts in Ringgold, Ga.
On April 27, just after 8 p.m. ET, an EF-4 tornado hit Ringgold, Ga. Working in North Carolina when the tornado touched down, Tad Agoglia, founder of First Response Team of America, and his crew packed up immediately and arrived ...
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The winery is located in the municipality of Göttlesbrunn in the Carnuntum wine-growing region of Lower Austria. The family owns the former parish cellar. Attached is a Buschenschank, where homemade Heurigen classics and game specialities are offered. Markus Lager is the third generation of the family to run the winery. The vineyards cover 8.5 hectares of vineyards, including the Rosenberg, Bärenreiser and Aubühl vineyards, mostly on south-facing slopes. They are 55% planted with the white wine varieties Grüner Veltliner, Pinot Blanc, Müller-Thurgau, Gelber Muskateller, Welschriesling and Sauvignon Blanc, and 45% with the red wine varieties Zweigelt, Cabernet Sauvignon, Merlot, Pinot Noir and Syrah. Since the 2019 vintage, the vineyards have been cultivated in an environmentally friendly, nature-oriented manner according to the certified rules of organic viticulture with, for example, the cultivation of flowering strips. Sheep graze between the rows of vines.
The cellar work is carried out with the most modern technology, but according to the non-invasive principle "wine quality is created in the vineyard" with as little intervention as possible. The white wines are partly vinified in the classic way to preserve freshness and fruitiness, but also in wood. The red wines are matured in traditional large wooden barrels as well as in barriques for up to 14 months. The premium wines include the Ried Rosenberg site wine (Zweigelt, Merlot) aged for 12 to 14 months in barrique and the local wine Göttlesbrunn (Zweigelt). The product portfolio also includes Frizzante and Pét Nat Rosé. Some of the wines are also bottled in magnum bottles. The winery is a member of "Die Rubin Carnuntum Weingüter".

domain: agronomy


text:
Durable and waterproof, with a handy slipcase and an easy-fold format, Lonely Planet Melbourne City Map is your conveniently-sized passport to traveling with ease.
Get more from your map and your trip with images and information about top city attractions, walking tour routes, transport maps, itinerary suggestions, extensive street and site index, and practical travel tips and directory.
With this easy-to-use, full colour navigation tool in your back pocket, you can truly get to the heart of Melbourne, so begin your journey now!
Durable and waterproof
Easy-fold format and convenient size
Full colour and easy-to-use
Extensive street and site index
Images and information about top city attractions
Handy transport maps
Walking tour routes
Practical travel tips and directory
Covers: City Centre, Docklands, Southbank, Williamstown, South Melbourne, Port Melbourne, Albert Park, South Yarra, Prahran, Windsor, East Melbourne, Richmond, Fitzroy, Collingwood, Carlton, North Melbourne, St Kilda
Map opens out to 630mm x 495 mm, printed on both sides.

domain: travel


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Ghum Hai Kisikey Pyaar Meiin fame Ayesha Singh to essay the lead role opposite Arjun Bijlani in an upcoming show
Ayesha Singh who rose to fame with her role as Sai in Ghum Hai Kisikey Pyaar Meiin has started getting fresh offers amidst the news of the main cast of Ghum Hai Kisikey Pyaar Meiin leaving the show.
According to the reports, Ayesha Singh has been approached to essay the lead opposite Arjun Bijlani in a show to be produced by the makers of Radha Mohan, Beyhadh 2. However, there are also reports about Ayesha declining the offer as she likes to give GHKPM her 100 percent till she is a part of the show.
Earlier in an interview, Ayesha rubbished the rumors of actors leaving the show due to remuneration issues. She cleared that the show is taking a generation leap, and the actors did not want to age on-screen. The show will move forward post the leap and the Chavan family will be retained on the show.
Sai and Virat”s fan (Ayesha Singh and Neil Bhatt) have been expressing their displeasure over the decision of generation leap. They have been trending that they will not watch the show without #sairat.

domain: celebrity


DE SCHEHERAZADE A YO, CARMEN
BY MARÍA PAGÉS COMPAÑÍA
Vanguard flamenco dancer and choreographer María Pagés premieres her feminine vision of Carmen. Hailed all over the world as one of the finest contemporary flamenco shows, it is a new take on the gypsy cigarette girl from Mérimée’s novella who was made famous by Bizet and the storyteller of the Arabian Nights. Pagés reinterprets these two central characters as women who are strong and proud of their identity.
Hailed all over the world as one of the finest contemporary flamenco shows, Vanguard flamenco dancer and choreographer María Pagés transcends two legendary female characters— Carmen, the gypsy cigarette girl from Mérimée’s novella made famous by the Bizet opera and the quick-witted storyteller of the Arabian Nights in this vibrant ode to femininity.
María Pagés & El Arbi El Harti Idea and Direction
María Pagés Choreography, costume design and musical direction
El Arbi El Harti Drama script and lyrics
Rubén Levaniegos, Sergio Menem, David Moñiz, María Pagés Music
José Barrios Choreography Assistant
María Pagés, Eva Varela, Virginia Muñoz, Marta Gálvez, Nuria Martínez, Júlia Gimeno , Sara Pérez Dancers
Ana Ramón, Sara Corea Singers
David Moñiz Violin
Sergio Menem Cello
Rubén Levaniegos, Isaac Muñoz Guitar
Chema Uriarte Percussion
Abu Dhabi Festival co-production with Gran Teatre del Liceu


Multilayer ceramic coils inductors boast 180nH at 100MHz
As a result, the existing lineup of products, which previously offered inductances up to100nH, was expanded with the addition of six new components with inductances ranging from 110 to 180nH. The 0603S series lineup now includes 62 components (E24 series) with DC resistance values ranging from 0.1 to up to 8.5 Ω, rated currents from 50 to 600mA, and inductances from 0.3 to 180 nH. The ceramic coils have an operating temperature range of -55 to +125°C and are designed for use in the RF circuits of mobile communications devices such as mobile phones and smartphones.
Visit TDK-EPC Corporation at www.tdk.co.jp


GORING Gap Boat Club is still improving its ... [more]
Friday, 05 March 2021
HENLEY 1sts maintained their unbeaten start to the year as they saw off the challenge of Southgate at Jubilee Park last Saturday.
The game started at a furious pace with plenty of space in the early exchanges. Both teams were keeping the ball well but not creating many clear-cut chances.
After 15 minutes a short corner was awarded to Southgate as Hetherington was judged not to be retreating five yards in a timely enough fashion. The short corner was duly dispatched by the Southgate forward via a deflection off a Henley stick.
Some good play from Henley’s midfield maestros of Rhys Joyce and Matt Riches created plenty of chances for the home forwards. A good ball from Joyce found Joseph unmarked in the D and his cross to Taylor at the back post was cut out by the Southgate keeper.
The rest of the half played out in similarly open fashion with only good defending by Soulsby, Hetherington and Mortimer and some good saves by Foggoa keeping the scores the same.
In the second half Joyce won a free hit on the half way line and hit a 50-yard aerial ball into the Southgate D which an unmarked Foster caught and volleyed into the top corner at the first time of asking to level the scores.
The next 20 minutes saw the umpires hand out no fewer than 10 cards, the majority to Henley for stick tackles, chat and dissent.
With Henley down to nine men for a good proportion of the second half, Southgate duly capitalised. Henley defended stoutly but a loose pass found a Southgate midfielder who passed a long ball into the D which was slapped first time past the diving Foggoa to put the visitors ahead.
With Henley back to a full complement, they were playing with greater intensity and having more and more chances in the Southgate circle.
A long scything ball up the pitch from Hetherington found Joseph in the D. Joseph waited for reinforcements and then crossed a sumptuous ball across the face of goal which fell to Foster to dispatch and level the scores once more. With five minutes to go Henley very much had the momentum and went in search of a late winner. Unfortunately against the run of play, Southgate hit Henley on the break. The ball was worked into the D and after some good saves from Foccoa and for what seemed like a lifetime of pinball in the Henley D, the ball was eventually smothered over the line by a Southgate forward.
The final play of the game saw Southgate win a succession of late short corners which were kept out well by the Henley rear guard.
10 February 2020
POLL: Have your say


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Children's Theatre of Charlotte
Oct. 4 - Nov. 3, 2019
McColl Family Theatre
This is a two-act show with intermission
Recommended for all ages | Two-Act, approx. 2.5 hours
Broadway’s timeless classic delights children and adults of all ages.
Fly to new heights in the Tony Award-winning musical that never gets old. Join Peter as he whisks the Darling children off to Neverland in a story filled with magic, delight and adventure. Together, with the help of everyone’s favorite fairy sidekick Tinkerbell, they’ll face-off against crocodiles, evil pirates and the villainous Captain Hook. With a sprinkle of pixie dust and a dash of imagination, Peter Pan will awaken the child in us all.
Want to enhance the experience? Purchase the Meet Peter Pan package, available after the Sunday, 2 p.m., performances on Oct. 6, Oct. 20 and Oct. 27. What’s included: Meet Peter Pan on stage immediately following the performance; take a personal photo with Peter Pan; receive a photo from the show signed by the entire cast! Cost: $20 per child
Schedule & Tickets
Through Sunday, November 3 ·
add to calendar
Children's Theatre of Charlotte, 300 E. 7th Street @ ImaginOn, Charlotte, NC, 28202
Call 704-973-2828 to order.
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Originally developed in 1897 as a painkiller, aspirin has become a valuable cardiology tool in the 21st century for preventing and treating cardiovascular disease. Because of the drug’s ability to reduce blood clotting, doctors commonly recommend a daily aspirin to patients at high risk or with a history of heart attacks, strokes, and other cardiovascular ailments. Extensive research has largely supported the drug as a cheap and effective way to prevent these life-threatening events and to help nullify what remains the leading cause of death in the United States.
But in 2000, a group of Boston cardiologists trying to identify risk factors that might predict poor outcomes after a heart attack made a strange discovery. Most of the predictive risk factors they discovered and ultimately incorporated into their well-known 7-point “TIMI risk score” made perfect sense. For example, if you came to the emergency room with chest pain and had an abnormal electrocardiogram or elevated levels in the blood signaling heart damage, you were more likely to be at risk for future adverse events. But the team also discovered one risk factor for predicting worse outcomes that was far from expected: the prior use of aspirin. According to their analysis, patients who were taking aspirin to prevent cardiovascular disease actually did worse after suffering a heart attack.
“It seemed to make little sense, because aspirin had clearly proven itself in other settings to be protective against heart attacks,” said Jonathan Rich, an instructor of medicine in the section of cardiology at the University of Chicago Medical Center. “If you suffered a heart attack, to prevent you from having another, your doctor invariably puts you on aspirin. So this unexpected discovery caught everyone’s attention. Did this mean that aspirin use could actually be hurting people?”
Dubbed the “aspirin paradox,” this observation did not deter doctors from continuing to prescribe aspirin for the prevention of cardiovascular disease. But the mystery caused some to wonder whether there was a biological reason for aspirin’s unexpected role as a risk factor, such as “aspirin resistance” in some patients, or if there was instead an epidemiological or statistical explanation. While working in Boston with the TIMI study group, Rich took charge of an effort to comb through the data for a way to explain the paradox.
The research ultimately led to a study, published last month in the Journal of the American College of Cardiology, which seems to take aspirin off the hook. When researchers controlled for a long list of potential confounding variables such as age, sex, smoking, and previous history of cardiovascular events, the association of prior aspirin use with a higher chance of post-event mortality entirely disappeared. Aspirin, they concluded, was not directly causing worse outcomes after a heart attack. Instead, it was simply a common drug that people with previous cardiovascular disease – by definition, a population at high risk for poorer outcomes, were frequently taking.
“Aspirin is probably an innocent bystander,” Rich said. “The reason people who take aspirin do worse than those not taking aspirin is because those taking aspirin have already suffered a heart attack, a stroke, or have heart failure for which they were prescribed the drug. In actuality, when we looked closer at the heart attacks that people suffered, those who were taking aspirin actually had less severe heart attacks than those not taking aspirin, suggesting that perhaps aspirin was indeed beneficial, but simply insufficient to prevent the heart attack entirely.”
That doesn’t mean prior aspirin use loses its status as a warning sign for adverse outcomes after a heart attack, Rich said. While the drug may not be directly responsible for the increased risk of “badness” after a cardiac event, it’s still a good predictor of who might need more aggressive care when they show up in the emergency room with chest pain. So, while the aspirin paradox loses some of its mystery, aspirin use lives on as a useful marker for physicians.
“In some ways, if all I am told is that there is a patient with chest pain and he or she is taking aspirin, I can safely conclude that the individual is likely at increased risk for adverse events and should thus be treated aggressively,” Rich said. “Prior aspirin use remains a very reliable marker of a cohort of patients at high risk of bad outcomes, and that is really what a risk score is supposed to do – help stratify patients into high and low risk groups. We can thus continue to use aspirin as a signal to identify the high risk patients.”

domain: medical


Gisele Bundchen Instagram Gisele Bündchen and Tom Brady
On Wednesday, a source tells PEOPLE that while the marriage between Brady and supermodel Bündchen, 42, is not "over by any means," the greatest quarterback in NFL history knows he will have to retire permanently from playing after the season to smooth over any issues after he retracted his February retirement announcement just over one month later.
"She doesn't hate that he's playing football, but she sure hates the way he handled the retirement and coming back," a source tells PEOPLE. "He knows that, and he's doing what he can do to smooth things over. He does know that this is his last season if he wants to stay married."
"He can't do this again," the source adds.
"So now all he can do is make this season count, spend time with his family whenever he can, and then retire at the end of the season," the source adds.
On Monday, Brady shrugged off rumors that he already plans to retire after his 23rd NFL season on his Sirius XM show, saying he will simply "take it day by day, and I'll evaluate everything as it comes."
George Pimentel/Getty Tom Brady and Gisele Bündchen
Never miss a story — sign up for PEOPLE's free daily newsletter to stay up to date on the best of what PEOPLE has to offer, from juicy celebrity news to compelling human interest stories.
"One of these days, they're going to be right, I will say that," Brady added, referencing those who try to guess his next moves. "One of these days, if you make enough predictions and so forth."
In a wide-ranging recent cover interview for ELLE's October issue, Bündchen shared she would like for Brady, 45, to "be more present" amid his busy football career as she continues to raise son Benjamin, 12, daughter Vivian, 9 and stepson Jack, 15.
"They decided together that he would retire, and then he decided by himself that he'd come back," the source tells PEOPLE about Bündchen's feelings on Brady's return to the NFL. "She said they'd talk about it more, but then he came back anyway, before they had really talked it all through."
"She's a very 'pros vs cons' person, and she sees very few pros to him playing anymore," the source added.


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Thimphu Centenary Farmers Market3280 Votes Currently Open
- Address: Main Town, Near the Wang Chhu River, North of Changlimitang Stadium, Thimphu, Bhutan
- Timings: 24-hrs Details
- Time Required: 01:00 Hrs
- Tags: Market, Shopping Center
A weekend in Thimphu is incomplete if you don’t visit the Thimphu Centenary Farmer’s Weekend Market. One of the largest domestic farmers’ markets in the country, it is always bustling with village folks and Thimphu residents alike, it is essentially a set of stalls on the banks of the Wang Chhu river, just north of Changlimithang Stadium. There is generally a healthy amount of haggling in pursuit of the best prices for the fresh, organic produce.Farmers from as far as Lingshi in the north, Tashiyangtse in the east, and Sarpang, Dagana and Tsirang in the south bring their farm products out to Thimphu for this weekend market. The vendors start arriving on Thursday and stay until Sunday.
The stalls are all crammed into a two-storied building, a real celebration of a market with over 400 stalls. You will find vegetables, fruit, meat and other farm produce on sale along with garlic, different kinds of chillies, red and white rice, various kinds of mushroom, fruit, balls of dates(homemade soft cheese) and freshly slaughtered pork and beef…the list in quite endless.
There is also a cafeteria and separate stalls for non-wood forest products. Across a cantilever footbridge, Kuendeyling Bazaam, to the west bank is a collection of stalls housing clothing, fabric and handicrafts, both local and Nepalese. You will also find a lot if religious paraphernalia such as prayer wheels, Lung Ta prayer flags, cymbals, horns and baskets.
Thimphu Centenary Farmers Market Travel Tips
- Entry is free.
- Come armed with your bargaining skills for best prices!
- Going early on Saturday means you get access to the fresh produce first, so try to go as early as possible.
Love this? Explore the entire list of places to visit in Thimphu before you plan your trip.
Fancy a good night's sleep after a tiring day? Check out where to stay in Thimphu and book an accommodation of your choice.
95% of people who visit Thimphu include Thimphu Centenary Farmers Market in their plan
11 AM - 12 PM
43.69% of people start their Thimphu Centenary Farmers Market visit around 11 AM - 12 PM
People usually take around 1 Hr to see Thimphu Centenary Farmers Market
92.98% of people prefer to travel by car while visiting Thimphu Centenary Farmers Market


text:
|Year : 2015 | Volume
| Issue : 1 | Page : 25-33
Clinical trial for evaluation of a Human Immunodeficiency Virus nosode in the treatment for Human Immunodeficiency Virus-Infected individuals
Director & Head, Research & Development, Mumbai, Maharashtra, India
|Date of Submission||28-Jul-2014|
|Date of Acceptance||12-Mar-2015|
|Date of Web Publication||31-Mar-2015|
Life Force, 411 Krushal Commercial Complex, GM Rd, Chembur, Mumbai ? 400 089, Maharashtra
Source of Support: None, Conflict of Interest: None
Clinical trial registration CTRI/2011/12/002228
Introduction: Identifying the need for strengthening of the immune system, the investigator has developed new Human Immunodeficiency Virus (HIV) nosode and evaluated its effect on HIV positive individuals through a clinical trial.
Methods: Standardized and the scientific method of HIV nosode preparation has been described and documented. Thirty-seven HIV-infected persons were registered for the trial, and ten participants were dropped out from the study, so the effect of HIV nosode 30C and 50C, was concluded on 27 participants under the trial.
Results: Out of 27 participants, 7 (25.93%) showed a sustained reduction in the viral load from 12 to 24 weeks. Similarly 9 participants (33.33%) showed an increase in the CD4+ count by 20% altogether in 12 th and 24 th week. Significant weight gain was observed at week 12 (P = 0.0206). 63% and 55% showed an overall increase in either appetite or weight. The viral load increased from baseline to 24 week through 12 week in which the increase was not statistically significant (P > 0.05). 52% (14 of 27) participants have shown either stability or improvement in CD4% at the end of 24 weeks, of which 37% participants have shown improvement (1.54-48.35%) in CD4+ count and 15% had stable CD4+ percentage count until week 24 week. 16 out of 27 participants had a decrease (1.8-46.43%) in CD8 count. None of the adverse events led to discontinuation of study.
Conclusion: The study results revealed improvement in immunological parameters, treatment satisfaction, reported by an increase in weight, relief in symptoms, and an improvement in health status, which opens up possibilities for future studies.
Keywords: Clinical trial, CD4, Homoeopathy, Human Immunodeficiency Virus, Nosode, Potentized, Ultra-dilution, Viral load
|How to cite this article:|
Shah R. Clinical trial for evaluation of a Human Immunodeficiency Virus nosode in the treatment for Human Immunodeficiency Virus-Infected individuals. Indian J Res Homoeopathy 2015;9:25-33
|How to cite this URL:|
Shah R. Clinical trial for evaluation of a Human Immunodeficiency Virus nosode in the treatment for Human Immunodeficiency Virus-Infected individuals. Indian J Res Homoeopathy [serial online] 2015 [cited 2021 May 7];9:25-33. Available from: https://www.ijrh.org/text.asp?2015/9/1/25/154345
| Introduction|| |
Human Immunodeficiency Virus (HIV) infection is characterized by a progressive loss of CD4+ T-cells and massive dysregulation of the immune system, which ultimately leads to AIDS. HIV pathogenesis is extraordinarily complex and begins its course of destruction during the acute phase of infection, which is characterized by robust viral replication concurrent with rapid infection and depletion of mucosal CD4+ T-cells. During the chronic phase of infection, CD4+ T-cells are slowly depleted in lymph nodes, effector tissues and blood, which persists until the majority of CD4+ T-cells are depleted and patients develop opportunistic infections and succumb to AIDS.
CD8 cell count can be a predictor of disease progress in HIV patients. Initial or serial elevated CD8 count while on Highly Active Antiretroviral Therapy (HAART) or an increase in CD8 count from HAART initiation may be early warnings for future treatment failure. A hyperdynamic or over-stimulated CD8 immune response, reflected by activation of CD8 subsets as well as elevated total CD8 count, may accelerate immune dysfunction and certain disease processes.
Antiretroviral Therapy (ART) regimes allow immune reconstitution but not normalization of the immune response. Therefore, additional therapeutic approaches need to be developed that include the use of immune-based therapy. Therefore, new innovative remedies having immunological potential to enhance the immune system, Standalone or along with anti-viral treatment, is the need of the hour. Identifying this need, the Investigator has developed homoeopathic preparation called HIV nosode and evaluated its effect on HIV-positive humans. He is interested in exploring ways to support immune response to prevent the progression of AIDS, as well as to reduce the number and intensity of opportunistic infections and to improve the overall state of health.
HIV research has grown worldwide and achieved significant success in the development of the antiviral drugs, which has changed Quality of Life for HIV-infected people and increased their life expectancy. However, these drugs do not cure the infection and their prolonged use often provokes significant adverse effects and results in the emergence of drug-resistant strains. Moreover, low level of viruses and latent viral reservoirs persist in HIV-infected participants. Flushing out these reservoirs is a major hurdle that remains to be overcome by anti-HIV therapy.
Important aspects in the management of HIV participants include
- Prevention of spread of HIV infection
- To slow the rate of multiplication of the virus. This for keeps the immune system of the patient healthy, for a longer period of time. Longer the person's immune system stays healthy the progress toward the development of Acquired Immune Deficiency Syndrome is delayed
- Preventing, controlling and treating opportunistic infections, catabolic wasting or cachexia, etc.
Hence, it is important to search for an effective, safer, better-tolerated alternative, which is natural.
Central Council for Research in Homoeopathy, India had conducted a multicenter clinical trial (1989-2005) with 870 evaluable participants using different homoeopathic medicines had shown positive role in managing people with HIV infection.  The placebo controlled randomized study had suggested a possible role of homoeopathic treatment in HIV infection in the symptomatic phase, shown a statistically significant elevation of baseline immune status in persistent generalized lymphadenopathy.
Nosodes are potentized, and extremely diluted preparations from the disease causing organisms used in Homoeopathy for the treatment of diseases but not restricted to those caused by the source organisms. Nosodes produced from diseased tissues containing Neisseria gonorrhea, Treponima pallidum, Mycobacterium tuberculosis, Smallpox virus, etc., have been in use in Homoeopathy since 1890. , The investigator has developed HIV and Hepatitis C nosodes and also have conducted human studies.
Extremely diluted and potentized preparations have shown to retain starting material in the form of nanoparticles.  Clinical efficacy of potentized preparations in HIV management has been shown in clinical studies.  Efficacy of homoeopathic medicine has been questioned by some in the past.  The law of similar, the fundamental homoeopathic principle, which states that any substance, which has a capacity to produce symptoms in humans, also has the capacity to relieve similar symptoms, if administered in very small dose.  As the HIV virus produces AIDS and related diseases, it was decided to examine the hypothesis of Homoeopathy through this study of examining the role of the HIV nosode in HIV-infected participants. The investigator has conducted Homoeopathic Pathogenetic Trial (a method to investigate the effect of potentized substance on healthy human volunteers, N = 22) of HIV nosode (accepted publication) and documented the capacity of the nosode to produce 130 symptoms in healthy volunteers.
- To prepare, standardize and evaluate safety of HIV nosode
- Evaluate the treatment of HIV nosode in HIV-infected participants in terms of reduction in viral load
- Improvement of immunological parameter such as CD4 and CD8 count and CD4 percentage, at different time points (12, 24 weeks and 12-24 th weeks)
- General health parameters.
| Methods|| |
Method of (HIV) Nosode Preparation
An Institutional Ethics Committee approved the project of HIV nosode preparation as well as the informed consent forms. Blood samples from HIV-infected consented donors (type I and II, one volunteer each) were collected for preparing the nosode. The volunteers were negative for other possible co-infections. Sera from two samples was separated, mixed, and processed for making the source nosode. Standardization of this source nosode with respect to viral count (4153 viral copies by Polymerase Chain Reaction (PCR) method in HIV type 1  (excluding HIV type 2 viral copies as the method for its quantification was (2010) unavailable), protein profile, and pH was done. One part of the source nosode was mixed with 99 parts of vehicle (water for injection or alcohol) and then exposed to rigorous process called potentization giving 10 strokes with standardized potentizer (electro-mechanical devise, impact of stroke calculated) to obtain 1C potency (10−2 ). One part of 1C was again mixed with 99 parts of vehicle to repeat the process, to arrive to 2C (10−4 ), and likewise 3C, 4C,…, 30C (1−60 ), etc., are prepared. Fifteen steps, a standardized and scientific method of nosode preparation with an example of HIV nosode has been described in detail.  The potencies up to 6C were prepared using water for injection, and above 6C potencies were made using alcohol as vehicle. The extremely diluted (potentized) homeopathic medicines are generally administered in 30C, 200C (or more) potencies.
Standardization of 30C potency and its safety in terms of absence of viral copies by PCR and ultra-electron microscopy was done. The 30C potency was found to be free from HIV virus.
Method of Clinical Trial with HIV Nosode (HIV Nosode was Coded as IMaid)
An exploratory clinical trial was conducted in 36 seropositive participants. Participants were enrolled in the study as per inclusion and exclusion criteria described in the protocol. CD4 absolute count more than 350 cells/μL was one of the inclusion criteria. HIV nosode 30C for first 3 months and 50C for next 3 months were prescribed to the participants. Participants were monitored every 6 weeks during follow-up visits. The dose of six pills (size 30) 3 times a day sublingual was administered to each participant. The documentation such as patient informed consent forms, laboratory investigations at the central laboratory, safety, and ethical measures were taken care of. The participants were followed critically for 6 months, and collected data were analyzed. Participants were monitored for CD profile and viral count at scheduled visits. Participants were examined by HIV AIDS specialist, specific investigations if required were done at central laboratory. Participants whenever required were referred to the counselor at the nongovernmental organization (NGO) for counseling as per the requirement.
Treatment in terms of reduction in HIV viral load compare to initial load (baseline), increase in CD4 count by 20% after 12 weeks or 24 weeks, decrease in CD8 count from baseline after 12 weeks or 24 weeks, change in CD4 %, percentage of participants for sustained reduction in viral load after 12 and 24 weeks of treatment, overall improvement in health (such as weight gain, improved appetite, less opportunistic infections) and health status reported by participant receiving 12 and 24 weeks treatment were evaluated. Treatment of responders (the participant who positively responded to nosode) and non responders was also reported.
Guidelines, Ethics, Compliance and Approvals
The project was reviewed and approved on 16 th September 2010, by Institutional Ethics Committee, (Homoeopathy India private limited) constituted as per Indian Council of Medical Research (ICMR) guidelines.  The requirements regarding the obligations of investigators as per 'Guidance on Good Clinical Practice' (GCP) and International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use Independent Ethics Committee  were met with. The study has been registered (CTRI/2011/12/002228) with the Clinical Trials Registry-India,  set up by the ICMR's National Institute of Medical Statistics.
Patients satisfying all of the following criteria were included in the study:
- HIV (Type I or/and II) seropositive, documented as per WHO guidelines, ≥350 CD4 + cells/mm 3 at the time of screening
- Who were never on Anti retroviral Therapy (treatment naive patients)
- Who had not received any experimental HIV vaccines
- Male or female between 18 and 65 years of age (inclusive, at the time of signing the informed consent and having an estimated life expectancy of more than 12 months)
- Having viral load of ≥500 copies/mL
- Able to receive an optimized regimen
- Free from any serious acute infection or serious medical illness within 14 days prior to study entry
- Ambulatory status, and ability and willingness to give informed consent
- Without actual or suspected allergies to any component of IP
- Female patients of child bearing potential must have a negative pregnancy test prior to IP administration.
- Female patients must agree to use effective birth control methods during the course of the study.
Patients satisfying any of the following criteria were excluded:
- Unable or unwilling to comply with the dosing schedule and protocol evaluations
- Any obvious indications for ART
- Clinical Stage IV (AIDS)
- Having opportunistic infection characteristic of AIDS and clinically suspected tuberculosis who were on or eligible for anti-Koch's therapy
- Clinically suspected and treated cancer
- Other critical diseases such as history of seizures, cerebrovascular accident or transient ischemic attacks, renal failure, liver failure, etc
- On injectable and oral corticosteroids
- Terminally ill patients, including AIDS, requiring hospitalization
- On any homeopathic medicine in last 1-month
- Pregnant and/or lactating women.
Independent agency (contract research organization) carried out data entry, and the data analysis after database was locked. Continuous data were presented by descriptive statistics N (number), mean, standard deviation, median, minimum and maximum values. Categorical data were presented as frequency (n) and percentage. Comparison of variables representing categorical data were performed using Chi-square or Fisher's exact test. Mean differences of continuous variables from baseline were examined by t-test or analysis of variance if more than two subgroups (factor categories) were included. All P values were reported based on two-sided significance test, and all the statistical tests were interpreted at 5% level of significance level. Analysis was carried out using Statistical Analysis System program. Efficacy results were on protocol population and safety was on the intention to treat population.
| Results|| |
59 participants were screened, 22 were excluded. Many of the participants failed to satisfy the inclusion criteria for CD4 count ≥350 CD4+ cells/mm 3 and satisfied the exclusion criteria of having clinically suspected tuberculosis who were on or eligible for AKT. 36 participants were enrolled in the study of which 9 did not provide outcome data while 27 participants completed the study. 8 participants were lost to follow-up and one participant voluntarily withdrew consent [Figure 1]. All participants were Asians, with a mean age of 34.39 (standard deviation = 7.98) years, mean weight of 56 kg; 83.33% of the participants in the study were males [Table 1]. All participants were only HIV type I infected. Most of the participants enrolled in this study were from NGOs and drug-addiction centers. Few participants were shifted to another NGO and hence lost to follow-up. However, the telephonic conversation with NGO confirmed the safety of such participants. Of 27 participants, seven responders (25.93%) showed a sustained reduction in the viral load from 12 to 24 weeks [Table 2].
|Table 2: Percentage of patients for sustained reduction in viral load after 12 and 24 weeks of treatment |
Click here to view
Overall the viral load is increased from baseline to week 24 through week 12 in which the increase was not statistically significant (P > 0.05) [Table 3].
|Table 3: Reduction in viral load (copies/ml) compared to baseline (PP population) |
Click here to view
18.52% (5 of 27) participants showed an increase in CD4 count by 20% at 12 th week with 30C potency of the nosode, not sustainable, as count of these participants dropped at 24 th week. With 50C potency, increase in CD4 count by 20% was observed in 14.81% participants [Table 4].
|Table 4: Proportion of participants with an increase in CD4+count (/mm3) by 20% from baseline to week 12 and week 24 |
Click here to view
Overall, it was observed that 37% (10 of 27) participants have shown improvement (1.54 - 48.35%) in CD4% count and 15% (4 of 27) participants had a stable CD4% count until visit 5. Thus, 52% (14 of 27) participants have shown either stability or improvement in CD4% at the end of 24 weeks. [Table 5].
In this study, 16 out of 27 participants had a decrease (1.8-46.43%) in CD8 count and eleven participants showed elevated CD8 count (not statistically significant), such an over-stimulation of CD8 response and an elevated cell count was clinically associated with accelerated HIV disease progression [Table 6].
No statistically significant change was observed in the CD8 count and CD4 percentage count from baseline to week 12 and week 24.
Weight gain was seen in participants at both 12 weeks and 24 weeks; the mean increase being 2.02 and 1.67 kg, respectively. Significant weight gain was observed at week 12 (P = 0.0206) [Table 7].
A significant proportion of participants, 63% and 55% showed overall improvement in either appetite, or weight gain or reduction in opportunistic infections at week 12 and week 24, respectively as per individual patient narratives for opportunistic infections [Table 8] and [Table 9].
|Table 9: Proportion of patients with the overall improvement in health by satisfying all of the criteria (n=27) |
Click here to view
Patient-wise short narratives were prepared, and the Investigator and HIV consultant opined clinically on the general health (weakness, feeling of well-being and treatment satisfaction) and improvement in terms of relief from symptoms and recurrence of infection. Sixty percent of the patients had improved in terms of the general condition, relief from symptoms and recurrence of infection.
3 (11.11%) out of 27 participants had infection at baseline. The number of participants having infections increased from 3 to 13 (of 27) at week twenty-four. Upper respiratory tract infection (5 participants) was the most commonly observed infection. One case of lower respiratory tract infection was observed. This may indicate the disease progression. Increase in fatigue from 0 at baseline to 4 at the end of 24 th week was observed.
22 (66%) of 36 participants experienced Adverse Events (AEs). None of the AEs was serious. Most of the AEs (72.73%) experienced by the participants belonged to the system organ class of infections and infestations, followed by 'respiratory, thoracic and mediastinal disorders' (40.91%) and 'general disorders and administration site conditions' (40.91%). The most common AEs reported were URTI (40.91%) and nasopharyngitis (40.91%), followed by pyrexia (31.82%). None of AEs and serious adverse events was suspected to be caused due to the study drug. All the AEs reported during the study were mild in intensity.
| Discussion|| |
The number of people receiving ART has increased considerably in recent years, with a notable increase of 900,000 in the number of people receiving ART since the end of 2011, until November 2012.  Antiretroviral therapies, focusing on reduction in viral load entail treatment with "drug cocktails". Currently, integrase inhibitors and entry inhibitors are new classes of anti-retroviral being investigated in clinical trials.  Research has also been pursued in the development of immunomodulators in the prevention or treatment of HIV infection. Alternative systems of medicine have explored the possibility of identifying therapies for HIV.
This was an exploratory study to evaluate a new homoeopathic medicine, HIV nosode, for the treatment for HIV. This study was conducted to examine the role of the HIV nosode in HIV-infected participants and to explore its efficacy and safety. Since this nosode was sourced from biological material, its safe use in human was documented carefully by testing for viral copies and genetic material. Inventor had also tested this nosode on healthy volunteers through a separate study, the Homoeopathy pathogenetic trial, and documented its safe use.
An overview of the results and the individual patient narratives reveal that most participants in different stages of the disease, experienced treatment satisfaction as reported by an increase in weight, relief in symptoms and improvement in health status, during their scheduled visits. The progression of HIV illness depends on the increase of viral load and depletion of CD4+ count. The efficacy of the HIV nosode may be evaluated on enhancement of CD4+ count and reduction in viral replication. The participants who responded positively to the nosode therapy had shown18.52% increase in CD4 at 12 th week with 30C potency of the nosode, not sustainable, as the count of these participants dropped at 24 th week. With 50C potency, increase in CD4 count by 20% in 14.81% patients, further follow-up of these patients not available to observe whether count sustained or not. In the responder group, 25.93% participants have shown a sustained reduction in the viral load from week 12 to 24. Overall the viral load increased from baseline to week 24; though the increase was not statistically significant (P > 0.05).
A mixed response was observed at week 24, wherein some participants improved and some had a relapse in their symptoms. Elevated CD8 count in eleven participants may show the HIV disease progression.  The limitation of the study was lack of the control group and hence it is difficult to arrive at the conclusion whether this fall in CD4 is related to the treatment or the natural course of the disease.
This also could point to the possibility that 30C potency gave a better result than 50C potency, as a shift from 30C to 50C led to weakening in results after week 12. Other limitations of the study were 25% dropout rate, small sample size, lack of the placebo arm and short duration. It may be noted that placebo control study has not been possible for a disease like HIV due to ethical reasons. A follow-up study to evaluate either the continuation of the lower potency (30C) for a longer duration or therapy for a shorter duration, and control group (randomized control trial) in a greater number of participants is warranted.
Author has conducted clinical trial in the participants having HIV infection to examine the fundamental Law of Similars used in Homeopathy. The homeopathic pathogenetic trial, a placebo-controlled study on healthy human volunteers conducted by the author has demonstrated effects of ultra-diluted, potentized HIV nosode in 30C potency by producing a set of symptoms comparable with those due to the HIV virus.
The mechanism of the action of the nosodes is not yet understood. The research may be supported by further study to examine if the action of the nosode as immunomodulator or immunostimulatory. It must be noted that this study is one of its kind involving homeopathic nosodes, which are vaccine like preparations sourced from organisms. The systematic effort has been made to evaluate its effect in HIV-inflicted individuals. The study may be considered a beginning of a series of many experiments with (a) different organisms and nosodes (b) evaluation of various biological markers (c) use of nosodes as adjuvant therapy (d) using nosodes along with constitutional homoeopathic medicine.
Clinically, improvement in terms of general condition of patient and improvement in CD4 count may help prolong the need for ART treatment; however, more clinical trials in a large number of participants with participants having homogeneous immune status are obligatory.
| Conclusion|| |
The most notable features of this study include results such as 25.93% participants showed reduction in viral load, 33.33% participants showed an increase in the CD4+ count by 20%, significant weight gain (P = 0.0206), 37% participants have shown improvement in CD4% count and 15% participants had a stable CD4%, and overall improvement in health status. The study revealed improvement in immunological parameters, treatment satisfaction, reported by an increase in weight, relief in symptoms, and improvement in health status. Taking into consideration the results of this study, homoeopathic therapy in the future can be explored as adjuvant or stand-alone, which opens up possibilities for future studies.
| Acknowledgments|| |
Members of Institutional Ethics Committee, subject experts for their technical, ethical, legal and medical inputs; and the volunteers for their participation in the study.
| References|| |
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Shah R. Hepatitis C Nosode: The preparation and homeopathic pathogenetic trial. Homeopathy 2013;102:207-14.
Chikramane PS, Suresh AK, Bellare JR, Kane SG. Extreme homeopathic dilutions retain starting materials: A nanoparticulate perspective. Homeopathy 2010;99:231-42.
Muraleedharan KC, Dey S, Prasad P, Siddiqui VA, Dixit R, Singh V, et al
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Shang A, Huwiler-Müntener K, Nartey L, Jüni P, Dörig S, Sterne JA, et al.
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Arjanova OV, Prihoda ND, Yurchenko LV, Sokolenko NI, Vihrova LA. Impact of adjunct immunotherapy with multi-herbal supplement Dzherelo (Immunoxel) on treatment outcomes in end-stage TB/HIV participants. J Antivir Antiretrovir 2009;1:86-8.
[Table 1], [Table 2], [Table 3], [Table 4], [Table 5], [Table 6], [Table 7], [Table 8], [Table 9]


A long-simmering spat between the Indian government and the country’s central bank came to the surface on Wednesday, after finance minister Arun Jaitley weighed in with a view on the direction of monetary policy.
In an interview with CNBC-TV18, Jaitley said that the Reserve Bank of India’s monetary policy committee should cut interest rates, given the country’s slowing economic growth and relatively low inflation.
Under prime minister Narendra Modi, the government has been pushing for economic reforms, including the controversial demonetisation of the economy, through the removal of more than 80% of the notes in circulation. The split has worried some foreign analysts.
‘I think the bigger issue is that the government is attempting to erode the independence of the RBI by pressuring it into loosening policy even further,’ Shilan Shah, India economist at Capital Economics in Singapore said. ‘Having meetings between the finance ministry and the RBI is ill-advised because it erodes the credibility of the RBI.’
The monetary policy committee, led by governor Urjit Patel, declined a request to meet by the finance ministry prior to the decision. The RBI decided to keep the repo rate unchanged at 6.25% on June 7, despite inflation figures continuing to be weak relative to India’s historical average. Core price inflation has fallen to below 4% since November 2016 and the latest quarterly GDP figure is at its weakest in two years.
Against this backdrop, the government wants to spur growth and investment by reducing borrowing costs.
‘The finance ministry wants to show that growth has picked up and that demonetization wasn’t a big factor. There are political considerations behind wanting lower rates,’ said Ashish Goyal, head of emerging markets equity at NN Investment Partners.
For its part, the RBI does not want to create an imbalance in the rates markets by cutting too much, too soon. Combined with external factors such as the UK elections, Middle East tensions and the US Federal Reserve’s actions, it is adopting a more wait-and-watch approach, said Mihir Kapadia, CEO of Sun Global Investments in London.
‘This has been a hard-fought battle on inflation by the RBI,’ said Credit Suisse’s Indian equity strategist, Neelkanth Mishra. Mishra, along with most analysts, expect one rate cut in 2017 as there is a case to be made for inflation to unexpectedly cross the RBI’s upper limit of 6%.
The second half of the year could see upward pressure on consumer spending. Farm loan waivers, healthy urban consumer finances, a possible pay rise for government employees, as well as a declining marginal cost of funds-based lending rate could leave the population with more disposable income, according to Sanctum Wealth Management’s CIO Sunil Sharma.
Going against consensus, Capital Economics’ Shah is convinced the next move in rates is going to be upwards. ‘There’s been a rebound in consumer demand and food inflation should pick up in the second half of the year as well,’ he said.
Whatever the outcome, he believes the interplay between the government and RBI is set to continue.
‘The government has been putting pressure on the RBI for many years now, so I don’t see that changing.’ Shah said. ‘But at the same time, the RBI has, perhaps, shown more independence in the face of government pressure than many would have expected. So for that, you have to give it credit.’


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