text:
Written by Jesse Mahautmr ETA’10-11
Before I ever really knew him, he was already looking out for me. It took just minutes after landing in Korea to have him securely placed in my pocket. He told me I could use him as much as I might need, and that I certainly did. Primarily at Orientation, during which my deficiencies in Korean were most glaring, he was a crutch I relied upon heavily. With every stopover by the university’s convenience store, every excursion into the neighboring Goesan city limits, he was my loyal companion, speaking for me with store clerks and thus saving me from embarrassment. He never complained, nor did he ever urge me to study Korean harder in order to gain some semblance of self-sufficiency. I knew it well, and so did he — this was far from a symbiotic friendship, as he stood to gain nothing from it.
Over time he slowly caught on, and as a result our relationship quickly turned sour. We gradually saw each other less and less until eventually we just stopped trying. My conscience getting the better of me, I sought to rectify our strained relationship and looked for him all over, but always to no avail. From time to time we’d cross paths when I’d least expect it, but the awkwardness was always just so overwhelming that nothing more substantive than a simple “hi” could ever be managed. It didn’t help that, on one of these occasions mid-Orientation, I ran into him in a Goesan stationary store and had no choice but to rely on his aid, the very thing that had wedged us apart in the first place. Without a doubt, this event is what propelled our relationship toward separation, because after it, we spent not a minute with each other for a good few weeks.
His disappearance from my life produced all those symptoms you’d expect from a typical bad break-up, as I was left to fend for myself on the mean streets of Goesan without the security blanket onto which I had become so accustomed to clinging since day one in Korea. As with any healing process, the first few days were the toughest to get past. Once those hurdles were cleared, however, I slowly began to gain that sense of self-reliance that always had seemed so far off in the distance. With the Korean language, I practiced more frequently; I listened more observantly; I studied more intensely. I knew that, if I put in the investment, the payoff was sure to be imminent.
Sure enough, toward the end of Orientation, my “veni, vidi, vici” moment finally did come to fruition; upon being told by the convenience store cashier how much I needed to pay for my goods, I successfully handed to her the exact amount, all on my own, without any of those “lost in translation” moments that had typified my every attempt prior. Only then did I realize that I could finally move on from him, that I didn’t need to depend on him to ensure my survival.
I didn’t see him again until the last day of orientation, when all of us were departing for our various locales around Korea. I tried to convince myself otherwise, but who was I kidding? He looked good. In my time away from him, I had forgotten just how comfortable it always had been to have him close to me. But that was all in the past, and I knew that reverting to this old mentality would do no good, especially in regards to the personal growth I had experienced while on my own.
When we met for the first time in weeks, I let out a sigh of relief at just how casual this exchange was proving to be. After the initial exchanges of laughter, I told him just how self-sufficient I had finally become, and he congratulated me on my newfound sense of independence. I apologized to him for my past transgressions and assured him I hoped to remain close friends, emphasizing that I would now only use him in cases of absolute necessity. I’m extremely grateful I was able to salvage our relationship, for life in Korea would be downright impossible without having him in those times of need.
I’ve said it once, and I’ll say it again: I’m so happy to have you back in my life, King Sejong the Great. May you continue to sit prominently on the back of that 만원 (manwon, or 10,000 won) bill, my friend. I hope you rest comfortably in my back pocket for whenever I might require your denomination.
When people in Korea begin a conversation with me, it doesn’t take long for them to realize just how far they’re going to get with me. As soon as I reluctantly open my mouth, they quickly discover, much to their chagrin, that I am not one of their own, despite my seemingly Korean appearance. In order to avoid their looks of disappointment, I always strive early on to keep a low profile and camouflage with my surroundings as best as I possibly can. A “blend, don’t break” mentality, I like to call it, I know I can pull it off so long as I draw no unneeded attention to my language deficiency. And that’s why I always considered King Sejong to be one of my closest allies.
Don’t know how much those cookies and chips cost? Just drop a 만원! Such was the strategy I employed without relent throughout most of Orientation. It was much easier to do this than it was to humbly apologize to the clerk and admit to her my lack of listening comprehension. As long as the value of my goods lay somewhere between zero and ten-thousand won, a range so wide that no more than quick price-eyeballing was necessary, then I was in the clear. What about those times when I might be too close to that threshold? Check-out twice, of course, and drop a 만원 each time to boot!
My 만원 dependency was a short-term fix to a long-term situation, and I soon learned the hard way that this strategy would not be the panacea to get me through my grant year. Once my stockpile of 만원 bills had disappeared, I knew that King Sejong would not be returning until my next payday, and I’d have to make do with the friends he left behind.
My motivation to master convenience-store dialogue was necessitated by the fact that I had no other option: if I wanted that late-night ramen, then I needed to learn. The adaptation of my reliance, from simply dropping a 만원 to actually learning the Korean language, closely parallels the differences between two forms of biological mimicry commonly witnessed in many diverse ecosystems.
In the first type of mimicry, termed Batesian mimicry, a harmless species replicates only the appearance and other ostensible features of a second, more harmful species. The mimic, however, does not incorporate whatever it is that actually makes the harmful species harmful. Thus the Batesian mimic utilizes subterfuge to dissuade potential predators from preying on it. Superficial at best, thinly veiled at worst, the Batesian mimic is akin to a knockoff Prada handbag, in that each, although roughly similar in outward appearance, severely lacks features when compared to what is genuine. The second form of mimicry, Mullerian, is much more robust than the former. Mullerian mimics adopt the actual harmful characteristics from the species it seeks to impersonate. This form of imitation is undoubtedly more powerful at staving off predation than is Batesian mimicry, since Mullerian mimics actually function as more elaborate replications of the original species.
Upon first arriving in Korea, the methods I utilized to adjust to my new environment were definitely of a Batesian variety. I had the Korean appearance down closely enough — I can thank my genetics for that — so all I had to do was adhere as tightly as I could to my “blend, don’t break” mentality. I soon discovered though that, even though those 만원 bills were able to help me out, a much more sustainable approach for greater longevity in Korea required becoming more Mullerian in my mentality. Thus I knew that I needed to let go of King Sejong’s hand; I needed to adapt more multi-dimensionally if I did not want to encounter the same hiccups over and over again throughout my grant year in Korea. While it certainly is still a work-in-progress, judging by how far I’ve come since then, I think I’m exactly where I need to be. I’m sure the Sejongs in my pocket would have to agree.


text: If you don’t have a beanfield to hunt in September, try to find one. They’re the surest early-season food source out there. “Shedding the summer coat and growing the winter one requires even more protein and energy than developing antlers,” says Dr. James Kroll. “When you start seeing deer’s coats go from red to gray, you know they’re seeking out protein. Soybeans are about 34 percent digestible protein, and that’s why deer swarm to them early in the season.” If you don’t have soybeans in your area, look for other green, high-protein chow. Alfalfa fields and clover plots are a reliable second and third option. But if soy grows in your area, find a field now.

domain: agronomy


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Now I know what you are all thinking: Not another Oiler fan losing it after a loss. But this is not the case. The 5-4 loss to the Penguins to make the Oilers lose 5 of their last 7 games was just the nail in the coffin.
The Edmonton Oilers are not playing good hockey.
Sure they only lost by one goal yesterday against a very good hockey team, right? Wrong. They were down 5-0 at one point, and at the end of two periods were down 5-1. A third period too-little, too-late comeback made it seem as though the Oilers played a good game.
So, why should Craig Mactavish be fired?
Well simply put, he is not a right fit for this Oilers team. MacT is a defense first coach. The Oilers are a team built around offense. Even our defense is better in the other teams end of the rink than our own.
We need to play a run and gun offense, and rely on scoring to win, not defense and goaltending. The reason why the Oilers were picked by so many people (including myself) to challenge for the Northwest Division crown was because our offensive depth would allow us to roll three legitimate scoring lines.
We were supposed to just bombard the other team and be a scoring machine. The reality? The Oilers are 25th in the NHL with a measly 2.62 goals per game. What happened?
Mactavish is trying to instill a defensive game on this team, and it simply is not working. The Oilers need to blow out opponents and score a lot of goals. They need to keep the pedal to the metal and never let up when they get a lead. They just are not good enough defensively to try to protect a lead without adding more goals.
Craig Mactavish is a good coach. He was able to take Oilers teams in the past who were just awful into mediocrity. Now, however, he has arguably one of the best teams in recent Oilers history, and they are once again mediocre.
People argue that he took us to the cup in 2006. But in 2005-2006, the Oilers had a very good team, and still had to fight for the eighth spot in the conference. The same thing is happening this year.
The team has not come out to play in the first period. They are last in the NHL with five goals in the first period this entire season. They have also let in the 10th most goals in the NHL in the first period with 13.
The players are lacking intensity, and some of that blame has to go to the coach. He isn't motivating them to play their hardest, and that's a problem. The only player he has called out during the season has been goaltender Mathieu Garon, who had little support.
Coaching is very important in the NHL. If you look at the Toronto Maple Leafs, they have a worse team than the Oilers. But they have a better record than the Oilers. Ron Wilson was not afraid to call out his players that were playing poorly, and he even benched them.
In the end, Mactavish does not seem to be working. Whether it's because the players are tuning him out since he has been there so long, or what have you, he needs to go. Year in and year out, the Oilers have been a mediocre team at best, and while the players have changed, the only constant is Mactavish.

domain: sports


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Yesterday was International Women’s Day, and, depending on the circles you run with or the country you live in, you probably heard about it. In many countries, International Women’s Day is somewhat similar to a combination of America’s Valentine’s Day and Mother’s Day. Friends and family celebrate the women in their lives with flowers and chocolates and warm wishes.
As a student involved in international affairs inside the classroom and out, yesterday was a great day to remember just how far women’s rights have come in many countries and how much work still needs to be done. My friends and I jokingly asked, “What about International Men’s Day? Does that exist?” And the reply was a sarcastic “Every day is International Men’s Day.” While this was obviously a joke and we all chuckled to ourselves, I can’t help but think about how true that is. In the same way that different ethnic groups have been fighting for rights in various countries for ages, the fight for women’s rights has too often been sidelined.
Women have made tremendous progress in the last century by redefining the words feminine and feminist; leading movements for the education of girls everywhere; becoming leaders in local, national, and global institutions; and showing everyone, everywhere that being a girl is a good thing.
Yet there’s so much more that we can do to aid the development of women. My call to action came when I saw the documentary Half the Sky. First of all let me say that this documentary is amazing, and it’s on Netflix so you should definitely check it out (it’s also a book, which is equally if not more brilliant). I watched the documentary in horror and disgust and so much hope.
“Women hold up half the sky.” What could be truer? Women make up half the population. There are quite literally billions of us, and nothing in this world would work if women didn’t help make it work. That alone was enough to make me want to jump up and do something, but I had to finish watching the documentary. I reached a part about Cambodia and the women there being trafficked into the sex industry. One woman, Somaly Mam, who had managed to make it out of the system turned around and charged right back at the problem. She helped locate and raid brothels, shut down trafficking rings, and opened up a sanctuary for girls to grow and learn and educate others. When she said, “Everyone can help. Everyone can do one thing. Start with your heart, what it wants,” I heard her. I decided that I would do something, so I applied and accepted a virtual internship with the U.S. State Department’s Office to Combat Trafficking in Persons. Now I submit open source reports on human trafficking in Eastern Europe and Central Asia. And I do it all from my couch at home. It turns out that doing one thing is far easier than it sounds.
So what’s my point? My point is that holidays to celebrate women are nice, very nice even, but action, even a small action, is far better. You can join a movement or NGO, or help a little girl learn how to read, or provide school supplies for girls in underprivileged areas, or support women in politics, or stand up for a girl being hit on at a party. You can do any of that and so much more. Be a part of the solution. Women will not be sidelined any longer.
DeAnna Miller is a senior at The Ohio State University studying International Studies, Russian, History, and Political Science. She also works for the Mershon Center for International Security Studies and U.S. Department of State.

domain: sociology


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25. The expert from EC, secretary of IWG for QRTV, informed GRB about the outcome of its last meeting held in Tokyo (10 – 12 December 2013). He also announced that the next meetings of the IWG were scheduled to take place from 7 to 9 April as well as from 13 to 15 May, 2014 in Washington, D.C. He clarified that the IWG activities were focused on cleaning up the draft text of the UN GTR on QRTV as well as on addressing technical and policy issues. The expert from EC thus invited GRB experts from Contracting Parties to the 1998 Agreement to provide before April 2014 their comments on the various policy options, provided by a working paper of the IWG (AVAS conditions 27.01.14). GRB also noted the decision of the Executive Committee of the 1998 Agreement (AC.3) (see ECE/TRANS/WP.29/1106, para. 106) to extend the mandate of IWG until November 2015. Therefore, GRB expected to discuss a concrete proposal at its next sessions in September 2014 and January 2015.
26. The expert from WBU highlighted three key elements of AVAS, from the point of view of people with impaired vision: (i) alert sound should be of a sufficient volume and its composition (frequency, etc.) should allow for location and movement of the vehicle; (ii) the system should be active on stationary vehicles; and (iii) the driver should not be in a position to switch it off, as this safety feature should be active all the time. The expert from EC informed GRB that the EU Regulation on noise would require an automatic setting of AVAS and since this Regulation was at the latest stage of the co-decision process, this provision would hardly change. The Chair of GRB clarified that the pause-switch function would be part of the discussion of GRB. He added that the provisions of the UN GTR should conjugate the safety effectiveness of AVAS and the reduction of parasite noise. Finally, GRB agreed to resume discussion on this subject at its September 2014 session.
35. At Chair’s invitation, GRB had a brief exchange of views on issues which should be included in the future work of GRB. The expert from ISO pointed out that, to update the test methods set out in UN Regulations Nos. 41 and 51, the following ISO activities may be relevant: revisiting ISO 362-1:2007, development of part III of this standard with a specification how to perform tests in indoor facilities and updating the requirements on the noise test track from ISO 10844:1994 to ISO 10844:2011. The expert from France mentioned UN Regulation No. 51, ASEP, QRTV, ongoing technological improvements, indoor approvals, addressing sirens (ambulances, etc.) in UN Regulation No. 28, noise pollution caused by loading and unloading of deliveries in cities. The expert from the Netherlands presented a graph (GRB-59-11) showing a general improvement in tyre noise data for C1 tyres in 2007-2013 and informed GRB about his intention to bring similar graphs for C2 and C3 tyres for the attention of GRB at its next session, with the aim to study if the current noise limits for tyres can be further reduced. With support from the experts from EC and OICA, he also suggested studying the correspondence between the labelling system on tyres and their actual performance. The expert from Switzerland was of the opinion that noise pollution, its benchmarking and new technologies emerging on the market should be looked at. The expert from ERTRO proposed to address the issue of road surfaces, as the third main contributor to noise pollution after vehicles and tyres. However, the Chair and the expert from EC pointed out that this issue is very complex and it goes beyond the competence of GRB and type approvals. The expert of EC proposed to revisit the noise emission of agricultural vehicles and update the underlying test methods which had been developed 40 years ago.

domain: news


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text:
A Vision Realized.
The Weston Playhouse Theatre Company Board of Directors created THE EWEN-FORT-STETTLER FUND to honor the extraordinary 30-year run of Founding Directors Malcolm Ewen, Tim Fort, and Steve Stettler and their artistic contributions to Weston, the State of Vermont, and the American Theatre. Their vision of the Weston Playhouse at Walker Farm has been realized and The Fund will ensure that it endures.
After 30 years of dedicated leadership, Mal, Tim, and Steve retired in the fall of 2018. During their tenure, the theatre grew from a summer stock company to a nationally recognized regional theatre. The Fund is an important part of our $13 million capital campaign and will support year-round programs. Weston Playhouse at Walker Farm boasts theatrical productions, a New Works Festival, workshops and readings, residencies and retreats, concerts, and community programs for all ages. Your support will ensure these programs continue to grow and flourish!
Leadership Gifts to the Fund may be pledged for payment over 1-5 years. Campaign gifts of $10,000 or more will be included on our Donor Wall.
For further information please email Director of Development Emily Schriebl Scott or call (802) 824-8167 x108.

domain: artistic


text:
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text:
Charles and Liza make amends and promise not to lie anymore, but Kelsey’s plans force Liza to withhold the truth. Lauren plans a romantic reunion. Sparks fly between Maggie and an enemy-
Things seem to be warming up between Liza and Charles, but a piece of intel and an exotic trip make Liza feel iced out. Kelsey moves into a new apartment, and Lauren throws her a housewarming party with a surprising ending.
Maggie debuts a new art show at an unconventional venue. Clare helps Kelsey at work, as their dating lives become intertwined. Liza convinces Charles to come to her literary salon where a major talent reads.
Liza and Charles work closely together to land a married writing duo. After Redmond calls her out, Kelsey takes drastic measures to keep an author she nurtured at her literary salon. Kelsey’s personal life gets complicated.


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text:
Dance of the Rings
After I'd finished the third Groundties book, I needed a break. Stephen's story is so intense, it was giving me his nightmares! So I thought: How 'bout a book about an adult with his act together! Maybe ... a fantasy! Wow. What a concept. I've been a fan of the Jane Austen/Georgette Heyer school of historical fiction since my high school days, and if I've ever based a character on anyone or anything, Deymio was based on the Corinthian (you should pardon the expression) archetype Heyer portrayed so beautifully. He rapidly took his own form and his own past, and (despite my best efforts) acquired Problems (their names are Nikki and Mikhyel), and my editor talked me into making him under 30 (just), but if you think of him as 35 or more, so much the better.
For the society, I wanted to avoid the medieval paradigm that a handful of authors out there write as if they'd lived back then, and I wanted to do something where the people have done the human thing and taken the "magic" to a practical conclusion (meaning some portion of the population was making a buck off it). The Rhomatum Syndicate of Nodes is probably most similar to the Greco-Roman style of mind-set and social structure, but there is no consciously constructed earthly paradigm. Such a parallel would be, in my opinion, inherently flawed as the very basis for the technology (a powersource equivalent to electricity that also creates a detritus-free environment---the sewers very literally feed the power-supply) has no earthly equivalent. I took the power-source/magic, and a couple of basic premises, and worked the rest out logically from that point. Technologically, they're right on the brink of the industrial revolution, but the limitations of the powersource, whose effects are highly localized, has created a technological conservatism that has kept them from stepping across that line ... yet.
The "magic" in these books stems from that powersource. There are leylines networking all across the Rhomatum Valley and where these lines cross---the nodes---humans can tap the energy of the ley. They build Towers in which they house the rings that control and direct the energy flow, there are ringmasters to control the rings, and an on-going battle between those who consider the ley a magical gift of the gods and those who consider it a simple fact of nature to be tapped for whatever humankind can get out of it.
And just when they think they've got it figured out ... along comes Mother.
Review copies were as rare with this series as with the Groundties series, however, here is what some fellow readers say about the books. In the interest of truth in advertising, I've included links to the pages with the full reviews, good and bad. The simple fact is, what I write and the way I write it isn't everyone's cuppatea. That's one reason I'm planning on making the original Groundties series as well as several excerpts available for free. I believe there are a lot of people out there who will like it, if only they try it.
Ring of Lightning
Anheliaa Rhomandi dunMoren, Ringmaster of Rhomatum is dying. Unless she finds a replacement, when she dies, the rings will spin out of control and the power umbrella that gives light and heat to the people of the city of Rhomatum will collapse, as will the power umbrellas of Rhomatum's satellite cities, the Rhomatum Syndicate of Nodes, and while Rhomatum can exist without her satellites, they cannot maintain control without Rhomatum. Obviously, Anheliaa's impending demise is of some interest to the ringmasters of the satellites. Historically, it has required a Rhomandi to control the Rhomatum rings. Unfortunately, her obvious heirs, her great-nephews, Deymorin, Mikhyel and Nikaenor, have displayed absolutely no Talent for controlling the great leythium rings.
This is not an ideal situation.
Anheliaa, being a rather arrogant sort, and a firm believer in keeping the control of the rings in the Family, so to speak, arranges to have her nephews provide her with an heir. Unfortunately for his well-being, but fortunately for my book, Deymorin takes extreme exception to her methods. Arrogance confronts bull-headed stubbornness and the resultant explosion catapults Deymorin into an adventure filled with lies and innuendo, a bit of politics, a touch of magic ... and a little invention that could blow a city-sized hole in a leythium-based economy: a battery.
And last but far from least:
Ring of Intrigue
In this, the sequel to Ring of Lightning, the Rhomandi brothers, Deymorin, Mikhyel and Nikki, return to a city in turmoil. Their great-aunt Anheliaa hangs on to life by the slimmest of Leythium threads, and Nikki's Shatumin wife, Lidye, has assumed control of Rhomatum Tower.
The web is disintegrating, taking with it the energy upon which the economy of the entire Syndicate depends. Suspicion runs deep, both throughout the Syndicate of Nodes and within Rhomatum Tower itself. The time is ripe for Rhomatum's takeover. The only question is, who will be the first to try? Their traditional adversary, Mauritum? The Kirish'lani to the south, perhaps. Or perhaps, one of the Syndicate's own.
As Deymorin strives to resurrect defenses that have lain fallow for generations, and Nikki struggles to bring order to a city in shock, Mikhyel finds himself following a trail of secret agreements and ancient feuds---a trail that leads him from the depths of Sparingate Prison, to the teeming trade city of Shatum, and finally to the decadent courts of Khoratum, and a fight for independence that penetrates to the heart of the leythium web itself.
A comment or three...
I've become aware (I don't consciously start out to do these things---honest!) that a recurring theme in my books is the question of perception, and the wrong-headed notions we get about people by judging them before all the facts are in evidence---prejudice in its purest form. Character is, in my mind, an issue of motivation as much as action. Absolutes rarely have meaning. Oh, I have my limits, but is it murder when the death of one person saves the lives of ten? or of a thousand? or of a way of life? Is it rape if the alternative is death? In a simpler, more immediate vein, is a person 'good' when they do and say all the 'right' things solely to make someone like them?
The intense third-person viewpointing lends itself extremely well to this aspect of storytelling. Thus far, all my books have multiple viewpoints (I think I had nine in Groundties!) but as a reader once you're in them, there's no escaping the fact that you're getting a prejudiced impression of both people and events based on the background and character of the viewpoint individual. As time passes, as you see those characters and events --- even that first viewpoint character --- from other's views ... you might learn that nothing is quite as obvious as it might at first have appeared.
So, don't be surprised if you find your own, initial impression of a character slowly shifting ... sometimes 180 degrees!
Ring of Destiny
With the Northern Crescent rebellion a thing of the past, the Rhomandi brothers settle into the task of rebuilding the physical, political, and psychological infrastructure of the Rhomatum Syndicate of Nodes. To their relief, in the wake of their show of solidarity and strength in the Rhomatum Tower, they find the task simpler than they'd dared hope.
In the way of things, they find their true challenges to be closer to home. Questions of who and what rules in the Rhomatum Tower, questions of the true fate of Khoratum, questions on the nature of the ley itself, and those who dare to control it.
And underlying it all, the question of the nature of three individuals, the question of whether the tempering of the past can overcome the prejudices of the present that could prevent them from fulfilling the promise for the future.
Yes, folks, it is written. And in my opinion, the most fun of the four. Unfortunately, in the time it took me to write 'Netwalkers and Change, the publishing industry had undergone some serious changes. DAW held onto the book for a few years, hoping, I guess, that the market would change, but it's only gotten crazier. In December I got the final word that they wouldn't be able to take the risk on a series this old and with, let's face it, somewhat less than best-seller numbers.
So . . . I'm going to have to find a different way to get it to you. Coming soon, or at least before the end of the year, an e-book version will be available on the Closed Circle site and (hopefully) on Amazon's Kindle site. I'm sorry it took so long and that I can't offer you a nice hefty book to read in bed, but at least the continuing adventures of the Rhomandi Brothers will be available at last.
I see this as the first of three books that cover the years between generations: RoC: Alizant, RoC: Ardiin (Who's he? Tee hee hee.), and RoC: Jerrik. All the brothers have children and the associated problems therein. But this is really Alizant's story (remember him?) Alizant and his generators are becoming an Issue and Alizant's peculiar Talent is coming to light.
However, we haven't forgotten the brothers. Deymio's getting married, Dancer's got baby-envy, and Nikki . . . well, poor Nikki has a child with Serious Problems.
Are you ready for some teasers?

domain: library


text:
Founded in 1978, by Dr. Robert Bradford, BRI® is a leader in developing proprietary metabolic biomedical diagnostic/monitoring equipment, technology and therapies.
Manufacturer of the Bradford BVPM® High Resolution Microscopy System for peripheral blood assessments. Use the menu to find information about this system as well as images captured during assessments.
BRI® research is also used in clinics around the world. Ingles Hospital is one such place.
Use the RESEARCH link to browse through research monographs and summaries from Dr. Bradford and other professional affiliates.
We offer a NEWS link that is updated often with recent developments at BRI®.

domain: medical


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If you receive a diagnosis of a fatty liver, it does not necessarily mean you eat a lot of fatty food, though a poor diet can be a contributor to the condition. Generally, if the liver allows fat to build up, it indicates that somewhere in the delicate dance of chemical reactions that is your healthy digestive system, something is awry, and physicians are noticing more and more frequently that fatty liver is connected to pancreatic function.
Nonalcoholic fatty liver disease, or NAFLD, is a diagnosis applied to early-stage liver disease that does not involve excessive use of alcohol 5. Alcohol abuse on its own can lead to fatty liver disease, and in both alcohol-related and nonalcoholic fatty liver disease, the condition is reversible 25. There are usually no symptoms. Untreated NAFLD can lead to further deterioration and eventually liver failure. Treatment protocols vary based on the underlying cause. Diagnosis generally occurs incidentally when blood work reveals elevated liver enzymes.
Fatty liver diagnoses began to rise in the late 20th and early 21st centuries as obesity reached epidemic proportions. Diets rich in easily metabolized carbohydrates might play a role in developing the condition, according to a 2007 “Obesity” study by David Ludwig, M.D., Ph.D., et al. The simple sugars in some carbohydrates drive a spike in insulin production. The pancreas releases this insulin directly to the liver. This response initiates the chemical processes required to store the extra energy as fat, and the liver is most susceptible to the fat buildup because of the high concentrations of insulin it receives from the pancreas.
Your pancreas releases just enough insulin at any given time to metabolize the macronutrients that are present. Some conditions, such as:
- metabolic syndrome
- which is characterized by excess abdominal fat
- can make the cells resistant to insulin
- so the pancreas must release more of the chemical to complete the task at hand
This flood of insulin builds up in the liver, accelerating fat storage and leading to NAFLD.
There are some indications in preliminary studies that fibrosis in the pancreas is associated with liver disease. An analysis of 1,000 corpses conducted by Edward E. Woldman, M.D., published in “The Journal of the American Medical Association,” found a high degree of association between the two conditions 4. In the 222 cases of liver disease, including fatty liver, cirrhosis or both, 156 of them also had pancreatic fibrosis.
- Children's Hospital Boston; Quick-burning Carbs May Cause Fatty Liver
- "Pancreas"; Nonalcoholic Fatty Liver Disease Is Related to Nonalcoholic Fatty Pancreas Disease; E.J. van Geenan, et al.; November 2010
- Gulf Coast Liver Support: Fatty Liver: Information for Patients
- "The Journal of the American Medical Association"; Relation of Fibrosis of the Pancreas to Fatty Liver; Edward E. Woldman, M.D., et al.; September 2011
- Mayo Clinic: Nonalcoholic Fatty Liver Disease
- Photos.com/Photos.com/Getty Images


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Season 12 of "American Idol" is just getting started, but what happens to those who almost made it to the top last season? FOX 9's Iris Perez caught up with local Idol hopeful Reed Grim to see what he's up to now.
Grimm has been pretty busy since he was cut from the show in Hollywood last march. After almost a year, he says life has been a whirlwind of growth.
"I know that it was supposed to happen as it did," he said.
Season 11 was an emotional roller coaster for the local crooner.
"Your dreams are right here -- your highs are so high and your lows are so low," he said. "You know, it gets crazy, but I guess that's the life of an artist."
Grimm auditioned five times to get on the show, but he said he saw his last audition in a totally different way -- almost as an observer of himself as he saw the judges respond.
"It was almost like an out-of-body experience," he recalled.
After securing a spot on the show and making it all the way to Hollywood, the Wisconsin native was deemed "too cabaret" by Jimmy Lovine and couldn't pull enough votes to stay. Now, he lives in Minneapolis, performing gigs with his family and spending time with his nieces.
Grimm is also working on his solo album, which he hopes to finish in 2013 -- and taking a lot of calls.
The former Idol contestant still has idols of his own -- including Stevie Wonder, Macklemore and Bobby McFerrin, and he also offered some advice for the new batch of hopefuls who will take to the stage.
"Breathe, trust yourself, be open, be a giver," Grimm said. "Give -- because the more you give, the more it's received."
While he may not have won Idol, Grimm said he his confident his destiny is still among the stars.
"I know that it's going to be music and art because I feel that it's vital to the human experience, more than people realize," he said.
You can catch Reed performing with his family at Manitou Station in White Bear Lake every Sunday night between 7:30 and 11 p.m.


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Visitors to EdVenture Children’s Museum will now be able to see how fresh vegetables go from a local farm through grocery stores to their tables.
The museum unveiled new additions to the Busy Bee Farm exhibit Saturday, sponsored by WP Rawl. The Pelion-headquartered farm is one of the nation’s largest family-operated vegetable farms, handling every step in the supply chain from growing, harvesting and processing to wholesaling and shipping. The hands-on exhibit lets kids see how it works all along the way.
“The farm used to be more of a classic storybook farm, but we wanted to get kids to understand more modern farming practices, and also connect them to farms that are right here in South Carolina,” said Matt Wicker, director of education for EdVenture.
The enhanced exhibit now allows visitors to pick produce out of the “ground,” see the modern tools, equipment and clothing used by farmers, and see the process of packaging the fresh food and getting it to stores and tables in the quickest and healthiest way possible.
“We are excited to provide an updated exhibit to our guests while showcasing current agricultural practices from farms in our home state. This exhibit will allow families to play together in picking fresh local produce, helping to spur conversations about where our food comes from and why we choose the foods we eat; whether it be for economic, dietary, environmental, or other reasons. Located next to our Neighborhood Market and Little Spot Diner, the process of Farm to Fork is highlighted throughout our exhibit space,” Wicker said.
More information on the new features is available at edventure.org.


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domain: food


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WAYNE – The Wayne Public Library announced their March Innovation Studios/Makerspace class schedule last week as there are several opportunities for community members to take part in hands-on activities.
Limited to three per class, instructors will help with the Embroidery Machine/Camera; CNC Router; 3D Printer; Vinyl Cutter; Laser Cutter; Heat Press and Lego Mindstorm.
For those interested, you must pre-register by calling the Wayne Public Library at 402-375-3135.
Upcoming events at the library:
Thursday, March 7: 5:30 – 7:30 p.m. Laser Cutter Class and 6-8 p.m. Needle Night
Saturday, March 9: 10:30 a.m. Winter Story Time; 1-3 p.m. Heat Press Class
Monday, March 11: 5:30 – 7:30 p.m. 3D Printer Class; 6-7:30 p.m. Smart Phone 101 Class (basics of smart phone use)
Tuesday, March 12: 5:30 – 7:30 p.m. Laser Cutter Class; 6 -7:30 p.m. Adult Coloring Night sponsored by Pac ‘n Save of Wayne
Wednesday, March 13: 10:00 a.m. Toddler Time; 5:30 – 7:30 p.m. CNC Router Class


text:
The administration of Irkutsk purchased 23 new buses for city routes, ten of which have large capacity, 13 — the average. All machines are equipped for people with limited mobility, they also set the GLONASS system, voice phone prompts, external and internal electronic boards, speaker driver with a lounge, modern engines environmental class Euro-4 and Euro-5.
For the purchase of buses this year was aimed 104,900,000 rubles. The following year, the city administration intends to 144 million rubles for the purchase of new vehicles. Within five years it is planned to upgrade the entire fleet of the city, as well as extend it by increasing the number of transport units.


In 2018 James Parker delivered a Develop Conference session full of such searing insight and devastating depth, that it was deemed too epoch-defining to ever see the light of day, hidden behind a vast network of conspirators and outlandish claims of "technical difficulties".
Unbowed, he returns in 2019 to the very institution that sought to silence him, to once again reveal the sort of uncomfortable truths that the so-called elites of the British games industry would rather you forget.
When not writing overblown conference biographies, James runs Bristol-based Ground Shatter and makes stupid action games.
Two indie games. Two Developers. Two stories of success and/or failure. In this unique session, developers James Parker and Anthony Gowland will go head-to-head to discuss development of their games, "RICO" and "Dead End Job" respectively. They cover the ups and downs, the similarities and the differences, and whether they remain friends or are now mortal enemies as their titles are both released in the complicated market conditions of 2019. With similar releases, budgets, and platforms, but different genres and styles - this is a rare opportunity to compare both real-world data and personal outlooks, see what factors have contributed to the games' relatives commercial outlooks, and draw meaningful conclusions about releasing a mid-budget indie game in the current climate. After all, what's better than one piece of anecdotal evidence? TWO pieces of anecdotal evidence, that's what!
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It’s really nice to see some of the younger people in our studio come to Develop, interact with other people in the dev community and make new contacts. I think it’s really important to learn from other people.
Develop is a really great way to network, it’s also great for going to talks and finding that little tip that you didn’t know before and thinking – oh I’ll bring that back to the team!
I absolutely love coming to Develop, it’s a brilliant, brilliant conference – you just know you’re guaranteed to meet everyone.
Jo Twist, OBE
There really is a huge mix of people at Develop - loads of peers that you can learn from and the perfect blend of every element of game development as well.
Develop is important – the networking is very important. And go to talks they’re inspiring and get your creative juices flowing, they can make you think and you’ll learn how other people do things.
Develop:Brighton is especially unique - it’s by the seaside and there’s a lovely relaxed tone that goes with that.The talks are cool, the networking is cool and having the opportunity to catch up with people – that’s always the excitement for me!
Develop is an excellent way of catching up with people – there’s a really nice community feel here.
Mike Bithell Games
Develop:Brighton’s a great conference. It’s got a spread of people from all parts of the games industry talking about such a wide range of topics.
There’s something creative about Brighton, so it’s the perfect place to have the conference.
We are so lucky to have Develop here in the UK. It’s a unique event where you can come and discover new things with people who care passionately about video games. It’s a sea full of new ideas.
There are many ways you can be part of Develop:Brighton 2020 - including speaking in the conference, taking a booth in the Expo or becoming a sponsor.Find out more


Top New Rock Artists Ranking is based on an artist’s chart performance on the Hot Rock Songs (which includes airplay, sales, and streaming data) and Top Rock Albums, as well as Boxscore touring ...WebWebWebWebStream songs including "Beyond The Vale", "The World (Is In Trouble Now)" and more. Listen to New in Rock by Apple Music Rock on Apple Music. Playlist · 149 SongsOctober 12, 2022, 6:26 PM · 13 min read. Music documentaries have been among the hottest and most lauded programming recently, from Peter Jackson's epic dissection of the making of The Beatles ...WebA highly talented guitarist, singer and songwriter, Johnson’s last release Unemployed and Highly Annoyed is nominated for a 2022 Blues Music Award for Best Blues Rock Album Of The Year. Johnson’s new album Hi-Fi Drive By (Ruf Records) finds him embracing more traditional blues, rock & roll, and swampy funk, complete with a smoking horn section.
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WebWebWebLet’s get to our monthly releases list, which we will also update the list if something changes below. 5 Rock and Metal Albums You Should Listen on November 2022 All Rock and Metal Albums...Streaming music online is easy using a computer, tablet or smartphone. All you need is access to the Internet, or, if you have a device, a data plan. Here are some of the ways you can stream music online.Web19-Oct-2022 ... Rock bands Mogwai, The Lanthums, and The Snuts all hit milestones. Each reached number one on the Official Album Charts with new releases.WebIf you enjoyed listening to this playlist, we recommend you to check: 1. Latest Rock Music 2022 - New Rock Songs 2022 English (Playlist Recent Rock Music 202...WebWeb


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English Motivational Quotes About Life. There are times when one feels sad, and everything in their life feels like it’s falling apart. Beautiful quotes of life in english tumblr.
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domain: psychology


text:
Nearly a half-century before Michael Brown and Officer Darren Wilson crossed paths on a street in Ferguson, Mo., a 21-year-old man named Marquette Frye was pulled over by the California Highway Patrol, just outside the Los Angeles neighborhood of Watts.
Both incidents unfolded on an August day, with a crowd of bystanders nearby. And both involved a patrol car stopped in a predominantly African-American community.
In 1965, Frye and his mother were arrested (and roughed up by officers), and an impromptu protest began. Soon the area was consumed by days of looting and arson in what came to be known as the Watts riots.
The parallels between the recent events in Ferguson and previous incidents and social movements in American history are many. Throughout the 20th century, interactions between police and African-Americans and other groups have led to public protest and violence.
Here is a sampling of the vast literature on the subject:
• Riot and Remembrance: America’s Worst Race Riot and Its Legacy by James Hirsch is one of several recent books detailing the long-forgotten history of the 1921 Tulsa race riot, in which armed white residents torched black neighborhoods in the Oklahoma city. The event began with the arrest of a black man after an encounter with a white woman in a downtown elevator; to forestall his lynching by a white mob, a group of armed black men (including many World War I veterans) arrived at the courthouse where he was being held. The sight of armed African-Americans (in
a state with Jim Crow laws) led to what amounted to a white pogrom against Tulsa’s black community.
• North From Mexico by Carey McWilliams (1949) focuses on the so-called “zoot suit” riots of 1943, which occurred two decades after Tulsa in Los Angeles. In the race riots that swept through the city, groups of mostly white servicemen beat up Latino youths. McWilliams witnessed the violence.
• Race, Police and the Making of a Political Identity: Mexican Americans and the Los Angeles Police Department, 1900-1945 by Edward J. Escobar is a more recent book (1999). Historian Escobar sees the zoot suit riots in the context of the many violent encounters with whites and police that helped forge the Mexican-American community in southern California in the first half of the 20th century.
• Fire This Time: The Watts Uprising and the 1960s by Gerald Horne is a detailed account of the events leading to the looting and arson that swept through south Los Angeles in 1965.
• Little Scarlett by Walter Mosley is a 2004 novel set in the community during the Watts riots. In an interview with National Public Radio, Mosley recalled living in Los Angeles in the 1960s. African-Americans were so angry at being marginalized (and of being the targets of police abuse) that even Mosley’s law-abiding father said he wanted to take a rifle and a Molotov cocktail and join the rioters (though he didn’t).
• The Contested Murder of Latasha Harlins: Justice, Gender and the Origins of the L.A. Riots by Brenda Stevenson (2013) details the 1991 shooting of an unarmed 15-year-old girl in a south Los Angeles liquor store. The incident again stoked the frustrations
in Los Angeles.
• Twilight: Los Angeles, 1992 by Anna Deavere Smith is the moving book (based on Smith’s one-woman play of the same name) about the enormous psychic toll the 1992 riots took on Los Angeles.
The rioting began just hours after four police officers were acquitted of beating motorist Rodney King, who had been pulled over for speeding. The beating was captured on videotape by a witness and widely seen on television. Even before the verdicts came in, an official report on the Los Angeles police led by Warren Christopher, who would later become secretary of state under President Bill Clinton, found widespread abuse in the department.
The highlight of Smith’s opus was a soliloquy by former gang member Twilight Bey. Riffing on the origins of his nickname and his sense of identity as a young black man, Bey says: “Twilight is that time of day between day and night. I call it limbo. So sometimes I feel as though I’m stuck in limbo, the way the sun is stuck between night and day in the twilight hours.”


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Find more from this author on:
About the author:
Krista would love to hear from you! Please contact her at [email protected] or friend her on Facebook!
What inspired you to write your book?
Living in a mountain town for part of my life and feeling trapped
Here is a short sample from the book:
Andrew’s brows pushed together for a moment as he watched me, then with a shake of his head, he moved behind me and wrapped his arms around me. The heat was instantaneous and not just from his arms. His cologne filled my nostrils, his body felt strong and warm behind me. I knew I should break away, to just deal with the cold rather than let myself experience these feelings stirring within me, but I couldn’t. I wanted to be close to him. I wanted to feel him touch me.
The lights in the Lake House dimmed and slowly turned off, the darkness enveloping us. I looked up to the heavens, feeling his breath on my neck. The stars twinkled in the clear sky, constellations and planets glimmering in their eternal dance. A splash of light illuminated the sky, followed by another and another. Colors exploded against the stars, streaming fire from the sky. The crowed oohed and ahhed as the night sky was filled with color.
I barely noticed the colors flooding the sky because my attention was on Andrew. His arms held me tightly, his warmth seeping into me and making my body ache for something I knew I could never have. I let myself believe for a moment, one beautiful moment, that this could work. That we could be more than friends. That I could kiss him, touch him, have him. That I could surrender myself to him and not be afraid of the consequences.
The sky was aflame with color for a glorious instant, then only streams of sparkling smoke and twinkling stars remained. The booms still echoed through the night, a rolling thunder following the man-made lightning. I turned my head slowly, feeling Andrew’s breath along my cheek. His lips were so close to mine that I could almost feel them. I wanted to taste those lips, red and open just centimeters from mine. He leaned in closer.
His lips were soft against mine. I wanted to merge into him, to never leave this moment. He tasted sweet, like cocoa and sunshine. My heart thudded with happy excitement and I pressed in closer.
The lights in the Lake house turned on, flooding the deck with artificial light. The moment was broken, and Andrew dropped his hands quickly to his sides, releasing me. In the harsh light, I couldn’t believe I had kissed him. I pulled my hat down low on my head, feeling my cheeks burn. I couldn’t look at him so instead I put my hands on the balcony, hoping he didn’t see how badly they shook.
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domain: literature


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STEM Education Thought Leaders Gather in Rockland
During the week of November 16-18, thought leaders from around the country in the field of Science, Technology, Engineering and Technology (STEM) education met at two separate events hosted in Rockland, Maine by the Island Institute. These gatherings were just the latest in a series of similar events since the Institute received its first National Science Foundation (NSF) grant for a STEM education project back in 2005.
The events attracted leaders in STEM education fields from Alaska, Ontario, North Carolina, Colorado and New Hampshire, as well as participants from the National Weather Service, the Maine Geological Survey, the Center for School Reform, the Maine Department of Education, the University of Maine, Bigelow Laboratory for Ocean Sciences, and Downeast Museum Services. Maine island and coastal teachers, fishermen and researchers came from Chebeague, Long Island, Newcastle and Friendship.
On Friday, a of team of STEM experts received an update from Ruth Kermish-Allen, the Institute’s education director, and Suzanne MacDonald, the organization’s community energy director, on the first full year of Energy for ME, an NSF-funded STEM education project focused on energy efficiency, serving middle and high-school students, teachers and residents from 10 island and remote coastal communities. They also brainstormed suggestions for the future of the project and how its impact could deepen for future participants.
On Saturday and Sunday, the Institute’s education team convened an inter-disciplinary advisory group that included some of Maine’s top research scientists along with teachers and fishermen from island and coastal communities. This group began developing ideas for the new WeatherBlur project, an NSF-funded online STEM learning community to facilitate discussions between students, fishermen, and scientists about the local effects of climate change.
Beginning with the Communities for Rural Education, Stewardship and Technology project (CREST) in 2005, the Island Institute has won competitive NSF grants of approximately $4 million for STEM education, and an additional $300,000 in funding from agencies and organizations including the U.S. Environmental Protection Agency and Time Warner Cable’s Connect a Million Minds initiative. For more information on these and other education programs at the Island Institute, please visit www.islandinstitute.org\education_services or contact Ruth Kermish-Allen at firstname.lastname@example.org or 207-594-9209 x117


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Leading member of UNISON slams Tory hypocrisy
We have received these comments from Dave Auger, a member of the National Executive Council of UNISON for the West Midlands. Dave was speaking to us in a personal capacity.
“The tax evasion scandal shows the hypocrisy of the Tories, and their claims to be against it, whilst evidence shows they have resisted any attempts to reform tax laws. But more importantly the Panama papers give us a glimpse of the sheer scale of international tax avoidance and evasion (and let’s be honest, only a rich man would argue the difference!).
The capitalist class has hidden £21-32 trillion dollars in tax havens around the world, that’s one third of total global wealth, OUR money! Yet it would only take, it is estimated, $240 billion to end world poverty. Claiming the end of Cameron would be no small victory, but only by ending the current economic system of capitalism can we ensure ALL global wealth is used for the benefit of ordinary people.”

domain: finance


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We tested the anticoagulation activity of free RNA aptamers, RNA origami tethered RNA aptamers, and DNA tiles bearing DNA aptamers using aPTT assay (activated partial thromboplastin time assay).
Non-modified RNA origami with aptamers showed no anticoagulation activity, because it was rapidly degraded in plasma.
The anticoagulant activity of RNA origami is at least six-fold higher than that of free aptamers.
To test anticoagulation activity of RNA aptamers on origami.
To find the optimum RNA origami that offers the highest anticoagulation activity.
Coagulation in human blood is the result of a complex series of reactions between various proteins in the blood called the Blood Coagulation Cascade (BCC). The aptamers used in the DNA/RNA tested here bind to one of the proteins in the BCC, thrombin. By targeting thrombin with DNA/RNA aptamers, the BCC can be inhibited, preventing, or at least slowing, coagulation. There are two exosites on the thrombin molecule that have already been targeted with DNA and RNA aptamers, called exosite 1 and 2. DNA aptamers patterned onto DNA weave tiles have been shown to effectively inhibit coagulation in human blood, however, RNA origami patterned with RNA aptamers had not previously been tested. One problem with RNA origami is that it is unstable in human blood plasma, therefore it needs to be modified with fluorine on the 2’ carbon in the ribose sugar in order to survive.
Inhibition of the BCC can be tested using an aPTT assay using a coagulometer. aPTT assays work by taking pooled human blood plasma which is Ca2+ deficient, and adding necessary reagents to work as surface activator. The surface activator begins the intrinsic path of the BCC, however, the lack of Ca2+ prevents the activation of factor IXa, preventing the common pathway of the BCC. The thrombin binding construct is then added to the sample, and is left to incubate. After incubating for five minutes, CaCl2 is added to the solution, kick starting the common pathway of the BCC and beginning coagulation of the sample. The time it takes the sample to fully coagulate starting from the addition of the CaCl2 is measured via the movement of a metal ball through the sample using magnets. When the ball stops, the sample is said to have completely coagulated. Using this method, the efficacy of the RNA constructs were determined. In order to give a comparison for the RNA origami, the previously created DNA aptamer patterned on DNA tiles were tested (4). RNA aptamers 1 and 2 corresponding to DNA aptamers P and B. Both fluoro-modified and unmodified RNA constructs were tested to showcase the ability of the modified RNA’s ability to survive in blood plasma.
RESULTS AND DISCUSSION
For the anticoagulation test, four aptamer arrangements for both DNA and RNA were tested in a Model ST4 coagulometer from Diagnostica Stago. No anticoagulant activity was observed for any non-modified RNA origami for all four aptamer arrangement designs, because non-modified RNA origami was degraded in human plasma very rapidly. The modified free aptamer offered low anticoagulation activity. The clotting times for exosite 1 and exosite 2-binding RNA aptamers were 37 and 52 seconds, respectively. The modified RNA origami tethered RNA aptamers showed remarkable activity compared to unmodified RNA tiles and free aptamers with coagulation times between 150 and 240 seconds. As expected, no anticoagulation was observed for modified RNA origami without RNA aptamers (2HF-RNA-NNNN) and for DNA tiles without DNA aptamers (2HT-DNA-NNNN). The anticoagulation activity of modified RNA origami was six-fold higher than free RNA aptamers (Figure 2). Additionally, the DNA aptamers presented on DNA tiles provided the same trends in anticoagulation activity as discussed previously in the literature, and have similar magnitudes of activity (4).
The RNA origami tiles with RNA aptamers successfully inhibited the coagulation cascade and displayed marked anticoagulant activity. The activity is six-fold higher than for free aptamers. The results confirm that the modified RNA survive for significant periods of time in human blood plasma. These two facts encourage further examination of RNA origami as a potential anticoagulant in surgical applications.
MATERIALS AND METHODS
The coagulation test was run in an activated partial thromboplastin time (aPTT) assay with a model ST4 coagulometer (Diagnostica Stago). 50 μL Pooled human plasma (George King Bio-Medical) was added in each cuvette, mixed with 50 μL aPTT reagent (TriniClot), and left to incubate at 37 °C for 5 minutes. 16.67 μL of 5 μM RNA origami sample, or buffer, was then added and incubated for an additional 5 minutes at 37°C. To activate clotting, 50 μL CaCl2 solution was added. The final concentration of RNA samples was 0.5 μM. The time to clot was then measured by the coagulometer and recorded.
Bompiani, K. M., Monroe, D. M., Church, F. C., and Sullenger B. A., A high affinity, antidote-controllable prothrombin, and thrombin-binding RNA aptamer inhibits thrombin generation and thrombin activity, J Thromb Haemost. 2012, 10, 870-80
Long, S. B., Long, M. B., White, R. R., and Sullenger, B. A., Crystal structure of an RNA aptamer bound to thrombin, RNA. 2008, 14, 2504-12.
Rangnekar, A., Nash, J. A., Goodfred, B., Yingling, Y. G., and LaBean, T. H., Design of Potent and Controllable Anticoagulants Using DNA Aptamers and Nanostructures, Molecules 2016, 21, 1-13
Rangnekar, A., Zhang, A. M., Li, S. S., Bompiani, K. M., Hansen, M. N., Gothelf, K. V., Sullenger, B. A., and LaBean, T. H., Increased anticoagulant activity of thrombin-binding DNA aptamers by nanoscale organization on DNA nanostructures, Nanomedicine., 2012, 8, 673-681


Serial wavelength dispersive XRF analysis.This article describes the latest development of Bruker AXS - S8 TIGER ECO Cement spectrometer, designed to determine the elemental composition of materials in cement production by successive wavelength dispersive XRF analysis. The device meets the requirements of ASTM C 114, EN 196-2 and ISO 29581-2:2010. An example of the spectrometer operation is given. It is shown that it provides both high accuracy and reproducibility of the analysis.
|Section: Control of production
|Keywords: X-ray fluorescence spectrometer, elemental analysis, materials for cement production.
You can apply for a subscription or order a specific issue of our journal here.


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LONDON (Reuters) – A consortium led by Spain’s Cosmen family has decided against making a takeover offer for National Express (NEX.L) after spending a month poring over the British bus and train operator’s books.
National Express said on Friday , however, that the Cosmen family had decided to support a proposed equity fundraising.
Last month, Cosmen and private equity partner CVC Capital Partners approached National Express with a proposed 765 million pounds ($1.24 billion) offer worth 500 pence per share, an improvement on a previous 450 pence approach.
National Express said on Sept. 11 it had opened its books to the consortium following the improved offer and on Sept. 25 the two sides agreed to extend an offer deadline imposed by regulators to give Cosmen/CVC more time to inspect accounts.
The company became a takeover target earlier this year after struggling to lower a debt pile of almost 1 billion pounds and announcing it would walk away from its flagship East Coast rail franchise due to mounting losses.
National Express said on Friday that it now planned to turn to shareholders for help get the company back on track.
“The board believes that strengthening the group’s balance sheet through an equity fundraising is now the most appropriate course of action,” it said in a statement.
“The Cosmen family has now confirmed its intention to support the group’s plans to undertake an equity fundraising within certain parameters.”
National Express did not say what conditions the Cosmen family, its biggest shareholder with an 18.5 percent stake, had attached to its participation in any fundraising.
Rival transport operator Stagecoach (SGC.L), which had been eyeing National Express’s British rail operations as part of the Cosmen-led approach, said it was no longer in talks with the consortium. (Reporting Paul Hoskins; Editing by Dan Lalor) ($1 = 0.6157 pound)

domain: economics


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Film Review: The Economics of Happiness
by Kristy LeissleApr 14, 2011
- Why are we so lonely when we have so much? Beyond the unhappiness of a disconnected world are new—and very old—ways we can turn it around.
The Moral Case for Change
by Gara LaMarcheApr 12, 2011
- It’s time to put the moral life back into our philanthropy and politics.
Our Human Nature
by David KortenApr 12, 2011
- Greed is a sign of moral and psychological immaturity. Psychologically and morally mature adults are caring, cooperative, and honest.
Turning Points: Is a Different Future Possible?
by John Cavanagh, Robin BroadApr 11, 2011
- With the citizen-backed blockage of a proposed aluminum smelter, is Trinidad and Tobago changing course toward a rooted future?
The Budget Agreement: No Occasion for Back-Patting
by Alan W. HousemanApr 11, 2011
- Lawmakers are congratulating themselves for averting government shutdown—but the nation's budget for 2012 is still out of balance.
Where Does the Labor Movement Go From Here?
by Amy B. DeanApr 06, 2011
- How the movement for workers' rights can harness the energy of the present moment.
Greed is Not a Virtue
by David KortenApr 05, 2011
- Wall Street's celebration and promotion of moral perversion as a virtue must be exposed and condemned.
Jon Stewart: Wait, Who’s Greedy?
Mar 30, 2011
- GE's not paying taxes ... and public employees are the ones we're calling "greedy, parasitic, and selfish?"
Young Voters: Don’t Write Them Off
by Rob "Biko" BakerMar 30, 2011
- Why anyone who believes that under-30 Americans aren’t tuned in to the future and ready to act is fooling themselves.
The UK’s March for an Alternative to Austerity
by D.D. GuttenplanMar 28, 2011
- More than 400,000 people poured into London's streets Saturday to show the British government what they think of its austerity program.
The Story of Refined White Rice
by Robin Broad, John CavanaghMar 28, 2011
- How a once nutritious grain was transformed into something unhealthy to eat.
The End of Empire
by David KortenMar 28, 2011
- Wall Street’s days are numbered. Ours need not be.
A Choice for States: Banks, Not Budget Crises
by Ellen BrownMar 25, 2011
- 7 ways state-owned banks could help states overcome budget deficits and boost their local economies.
We’re Number One!
by James Gustave SpethMar 22, 2011
- America is number one in quite a few areas—but they're not all accomplishments to be proud of.
A System Designed to Crash
by David KortenMar 21, 2011
- To create a stable functioning financial system, we must first understand why the current financial system holds policy makers hostage to Wall Street interests. It is more than just political corruption.


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I prefer removing the chain and giving it a thorough cleaning about every 3,000 miles, but with the newer chains (mine is a 10 spd Campy Record), there is not a master link, so it's not a good idea to remove the chain. This unit does a very nice job cleaning the chain! I am happy with it (as I am with most everything from Park Tool) and would recommend it to anyone who asked!
My old chain cleaning tool broke so I had to pitch it (don't recall the manufacturer of it) but this one by Park Tool is made much better and is easy to use. I wish it contained a larger container of chain degreasing fluid (I had three bike chains to clean) but you can't have everything.
Got this product because I was destroying shop rags and sponges everytime I washed my biks. In addition, This is a great way to keep your hands clean if you just want a quick clean of the chain if they bike isn't so dirty.
Overal the cleaner does it's job, but has following flaws compared to Finish Line
- requires more detergent because of a different design
- uses two small clips to hold the top component in place, which requires twice the number of moves to open and close, finish line only has one, and it's sturdy enough
- in general feels like it requires more time to clean a chain with it (that's very subjective personal opinion)
The device is easy to set up and use despite the unclear instructions. Example the instructions say to put the rear chainring in the smallest setting. They really mean Shift the front derailleur to the smallest ring. If you dont, expect to see the chain jump off.
It does a good job of cleaning

domain: hobby


Over the past week, furor ensued over the Pope’s upcoming encyclical this summer on environmental degradation. It is clear that it will detail the effects of human-caused climate change on the poor, and on economic development. Will it help?...Read More: Pope opens the door to the economic opportunity of the century?
Your average, run of the mill incandescent light bulb lasts about 1,500 hours… the same amount of time of the bulb developed by Thomas Edison just about 137 years ago lasted. Thanks to the power of innovation, nearly every...Read More: Uncle Sam tells Thomas Edison to move over
The business case for energy efficiency is already a strong one, yet it becomes even stronger when rebates or other incentives are available through local utilities or the government. These programs, which can often cover up to half the...Read More: Searching Beyond the Rebates
Yesterday I was relaxing with one of my favorite shows, Modern Family. Their holiday episode featured a scene where father and son team Jay and Manny had set out to find the perfect Christmas tree. Jay insisted on getting...Read More: A Holiday Exploration into Life Cycle Assessme


A new or rebuilt power chair joystick is one of the most important items that we sell. Functioning as the user interface between the power chair operator and their mobility chair, a high-quality Invacare or Pride joystick controller is a combination of driver's dashboard and keyboard. Our off the shelf joystick controllers can be mounted on either side of the power chair.
One of the most significant advancements in personal mobility technology has been the adaption of the gimbaled joystick controller for electric wheelchairs. The immeasurable benefits of enhanced mobility and independence have made the electronic joystick almost as much of a necessity to millions of people as is the oxygen they breathe or the food they eat. Monster Scooter Parts offers our customers both brand new factory OEM units from the major manufacturers, as well as top-notch aftermarket units made by Dynamic, Q-Logic, and other respected joystick manufacturers.
We also offer our customers a convenient power chair joystick diagnostic service for those users who prefer their joystick unit repaired rather than replaced. Whether your requirements call for a new off the shelf Pride joystick or a functional rejuvenation of an older Invacare or other brand, Monster Scooter Parts can help keep you mobile.


“The World of Apu” is a bimonthly, diverse, and multilingual online film magazine which explores film cultures from around the world.
Below you can find my analysis on the Qatsi trilogy. A cinematic statement about civilisation, technology, nature, and the relationship among the three. A trilogy left behind in the shadow cast by blockbusters, forgotten by time, buried in oblivion.
A little girl is trying to cope, after having lost her mom, while dealing with life itself, bullies, and her father with his new girlfriend by putting together… a robot.
A low budget, indie, PG film which Jax Productions and Stay Relevant Productions managed to bring to life with respect to family values. Loss, grief, rejection, love, and self-reflection have been responsible for causing all of us sleepless nights throughout the course of our life. And Paulina Lagudi, with skill, imagination, and artistic temperament produces, writes, and directs a heartfelt story on nights like that.
Josh Hopkins does a brilliant job as a dad trying to do his best, and it’s really nice to see the always mesmerizing Charisma Carpenter as the “woman next door” relying solely on her acting. Last, but definitely not least, look out for the incredible Madison Horcher and Emma Rayne Lyle who, given the opportunity, will be two of the most sought-after actresses of their age.
An old man who fits the Santa Claus profile becomes a symbol for a company, a family, and a nation alike.
Richard Attenborough, Elizabeth Perkins, Dylan McDermott, and Mara Wilson give a great performance in a film for the whole family. Legendary John Hughes behind the production and director Les Mayfield remake the 1947 version of the homonym film with humour, fantasy, great photography, camera work, and editing. Gather the family and enjoy!
An old chap found on the street, who has not been vetted whatsoever and officially claims he is Santa is trusted by a family, a major company, and a nation to be near kids.
My, oh, my… Folks gather round! A major company whose CEO’s last name is “Cole” hires a guy for its representative Santa Claus who looks like the 1930’s Santa Claus, property of Coca Cola – “Coke”. And all of us… worldwide… to this very day… religiously… still pass the same torch from generation to generation.
But our generation is evolutionary! We keep walking while texting towards the third decade of the 21st-century with our wireless headphones on because seeing and listening in life is for the backward-looking.
I’ll be quick, and as this is a PG film, I’ll be lenient too…
Writing an “original” script nowadays is hard enough. Directing it in an “original” way, even harder. Oliver Daly, writer/director of the short film Miles (2015), pens the script and directs its feature version “A-X-L”. A kid and (not) his robotic dog’s adventure can be pretty much summarized as “E.T. the Extra-Terrestrial” (1982) meets “Transformers” (2007).
Decent story, offering nothing much to its development or its characters with more holes than a swiss cheese that a kid would scratch its head. I know women who would die to find out how after 48 hours of running around the makeup stays intact and the hair straight as an arrow. And I’ll sound like a broken record again, but… Producers… don’t hire only models for underwear.
David S. Goyer has been a brilliant writer and producer for the past three decades and still is. I guess hit-and-miss is part of every job.
Stephen Chbosky does his wonder once more – Yes, pun intended. Following the mind-blowing “The Perks of Being a Wallflower” (2012), he now pens the screenplay and directs “Wonder”. In a nutshell, a homeschooled child suffering from mandibulofacial dysostosis, also known as “Treacher Collins syndrome” (facial deformity), attends for a first time a public school, entering the 5th grade.
Julia Roberts and Owen Wilson do an amazing job as the parents who struggle as much as their kid, and Jacob Tremblay, being the kid, proves again he is a prodigy child actor. Izabela Vidovic, Daveed Diggs, and all the child actors shine in front of the camera, with everyone knowing who they are playing and why.
“Wonder” is the side of Hollywood which gives hope that studio films are not all about undermining human intelligence, explosions, or exploiting disabilities and minorities for profit. Its plot and subplots are bound together proportionally, creating a perfect equilibrium. It recognizes talent, maneuvres around and delicately avoids buffoonery, soppiness, kitsch and cliche, and definitely recognizes a$$holes when it sees them, in every shape, age, race or form.
Get carried away and let it appeal to your humanity. As reality is, unfortunately, far more inhuman…


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Gov. John Bel Edwards on Wednesday (April 19) officially declared Louisiana's coastal land loss an emergency, a move he hopes will expedite a host of restoration projects mired in federal permitting. "The Louisiana coast is in a state of crisis that demands immediate and urgent action to avert further damage to one of our most vital resources," he said.
The proclamation is to be sent to President Donald Trump and members of Congress. Edwards wants Trump to declare coastal erosion a national emergency and pressure the Army Corps of Engineers and other federal agencies to speed approvals for sediment diversion projects and other initiatives outlined in Louisiana's $50 billion, 50-year coastal master plan. The 2017 update of that plan was unanimously approved earlier Wednesday by the state Coastal Protection and Restoration Authority.
Edwards also is asking Congress to change federal laws to exclude coastal restoration projects from environmental laws. In the alternative, he asked that Congress allow approvals under a special fast-tracked process.
The proclamation was requested by coastal authority Chairman Johnny Bradberry. "This clearly highlights the support and recognition that Gov. Edwards has about the criticality of the state of our coast, and further demonstrates that he is clearly is a coastal governor," Bradberry said.
The coastal authority says about 2,250 square miles of Louisiana will be lost over the next 50 years if urgent action isn't taken. Coastal marshes and swamps that serve as barriers against storm surges and flooding are fast eroding, putting businesses, homes and lives at risk, Edwards said.
"Immediately addressing this crisis will rejuvenate Louisiana's economy and provide benefits across generations and positively impact the nation's economy," he said.
- Read the governor's declaration:


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When your 1965-1979 Corvette is ready for new Rear Spindles and Bearings, this is the complete kit to get the job done right the first time! Precision spindles and matched bearings are your guarantee for trouble-free driving. Don't wait for disaster to strike leaving you stranded. Kit includes components for driver and passenger sides.


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Rediscover the essentials of the Bistronomie
From 12 pm to 6 pm, the bar Le Baudelaire is the perfect place to enjoy a lunch break that is both informal and sophisticated. The refined and delicious cuisine offered here celebrates the classics with a hint of modernity. For his entrées and dishes, the Chef invents and reinvents refined specialities, enhanced by his masterful hand and prodigious talent. For dessert, to conclude the meal on an irresistibly sweet note, the pastry chef presents his light and delicate original creations as well as his remastered classics.