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Published On: February 18, 2014
By: Dorothy Gonzalez, Georgia
HOW TO MASTER BREATHING IN THE FREESTYLE
how to master breathing in the freestyle
Developing a good breathing technique is perhaps the biggest challenge for beginner and intermediate swimmers. Problems with breathing can easily knock on into other parts of the stroke. For instance, breathing can cause scissor kicks, poor body position, cross-overs and lop sided strokes.
Many swimmers have a problem with their stroke that is related to their breathing technique without realising that their breathing is the cause of the problem.
Below we`re going to take a quick look at good breathing technique and common problems. We`ll also give you 7 tips to improve your breathing, try them even if you don`t think you have a breathing problem - you may be surprised!
exhale strongly into the water between breaths
Exhale strongly into the water between breaths.
Tip 1. Focus on Your Exhalation Not Your Inhalation
The most common problem swimmers have with their breathing is not exhaling under the water. If you exhale under the water between breaths you only have to inhale when you go to breathe. This makes things much easier. It also relaxes you and helps greatly with bilateral breathing.
This is so important and can make a massive difference to your swimming.
We`re hot on this - check out our key article on exhalation: You Know Your Problem, You Keep It All In!
Tip 2. When you`re not breathing, keep your head still
In between breaths, hold your head still in one position. Don`t roll it around as your body rotates - this will make you dizzy and will really hurt your co-ordination!
Keep your head stationary when not breathing, just like our animated swimmer Mr Smooth.
If you`ve think you roll your head, concentrate on looking at one point on the bottom of the pool. Only turn your head to breathe. This will feel a little strange at first but should quickly start to feel much nicer. You`ll find you feel much more coordinated with the rest of your stroke too.
If you`re struggling to co-ordinate holding your head still - try this visualisation. Imagine a half-full glass of champagne is sitting on the top of your head and you`ve got to keep it very still or it`ll spill! Sometimes thinking of it like that can do the trick.
You can practise at the shallow end or on dry land by bending forwards at the waist and performing pretend strokes while holding your head still.
Tip 3. Breathe Into The trough - Your Bow Wave Is Your friend
When you move through water you create a `bow wave` with your head and body, just like a boat does. The shape of the bow wave means the water level drops along the side of the swimmer`s face.
breathe into the trough or `pocket`
Breathe into the trough or `pocket`.
This creates a trough either side of your head and body that is beneath the surface level of the pool - so there`s air lower than you might expect there to be.
Breathe into this trough and you don`t have to lift your head to inhale.
Sometimes swimmers call this `breathing into the pocket` as it feels like there`s a pocket of air there by your head.
You don`t have to swim fast to create a bow wave, even swimming slowly creates a decent pocket for you to breathe into.
Many swimmers don`t realise the bow wave is there and try and lift or over-rotate their head to take a breath. That`s a big mistake, as we`ll explain in tip 4.
Tip 4. don`t lift Your head
don`t lift you head to breathe!
Don`t lift your head when you breathe!
The problem with lifting your head to breathe is that your body acts like a see-saw and your legs sink. This adds lots of extra drag.
With the trough or pocket of air by your head you don`t have to lift your head up to breathe. To breathe into the trough you just have to rotate your head a little without lifting it. If you try and lift your head you disturb the bow wave, reducing the trough. Also, when lifting your head you tend to breathe too far forwards - and try and breathing over the high front of the bow wave.
So, lifting your head disturbs the bow wave - it`s a vicious circle. Instead of doing this, trust the pocket to be there and keep your head low.
Look at the shape of the bow wave. Don`t lift your head and try and breathe on the peak of it.breathe into the trough or `pocket`
Instead, breathe into this pocket.
If you are struggling to find the pocket, a good drill to practise is to swim with fins (flippers) in a superman position - one arm out in front of you and the other resting by your hip. Kick gently on the side of your lead arm and look down at the bottom of the pool. When you are ready to breathe, simply rotate your head slightly to find the pocket and breathe. Don`t hurry this, kicking with the fins will keep your moving forward so you can feel the pocket with your mouth.
Tip 5. Don`t Over Rotate Your Head
A similar problem to lifting your head is rotating it too far - so you are looking upwards instead of to the side when you breathe.
breathing upwards can cause scissor kicks
Over-rotating your head and breathing to the sky effects you balance and often causes scissor kicks.
This is bad technique because it causes your body to over-rotate onto your side and cause a loss of balance. To support yourself you tend to cross-over with your lead hand creating a banana shape with your body. This causes you to snake down the pool from one side to the other. A scissor kick is also very likely.
To correct this, you need to get used to breathing into the trough. Use the kick on the side drill we suggested in tip 4 and when you breathe try and keep your lower goggle in the water so you have one eye below the water and one above.
If you are struggling to do this, swim in one of the side lanes of the pool and have someone walk on the edge of the pool beside you and ask them to keep their feet about level with your shoulders. As you swim and turn to breathe, look at their feet square on.
Mr Smooth has good body roll - he hardly has to rotate his head at all to breathe.
If you develop a stiff neck whilst swimming, it`s very likely you are either lifting or over-rotating your head to breathe. This puts great strain on your neck muscles. Improve your breathing technique and the stiffness should quickly go away.
Tip 6. A lack of Body Rotation Could be hurting your breathing
Good body rotation is a massive help to your breathing. That`s because once you have rotated you don`t have to turn your head much further to breathe. If you are struggling to breathe, perhaps to one side, poor body rotation could be your problem.
For the full story on developing good body roll, check out our technique article on body rotation.
Tip 7. Learn to Breathe Bilaterally
What is `bilateral` breathing? It`s jargon for breathing to both sides. You could do this every 3 strokes as Mr Smooth demonstrates here. Or swap sides occasionally, e.g. breathe twice to one side then twice to the other.
Here at Swim Smooth we believe that learning to breathe bilaterally is an investment that will pay you back every swim for the rest of your life. That`s because it helps develop a symmetrical stroke technique which will make you cut straighter through the water.
If you only breathe to one side it`s very likely your rotation will be poor to your non-breathing side and you won`t swim in a straight line. We`ve seen these problem time and time again with swimmers who only breathe to one side.


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The Sweaty Palms blog is a place for artists to exchange ideas and voice opinions on theatre, art, and culture. We welcome contributions from artists of all levels and mediums. Come be part of the conversation!
Sweaty Palms Productions is launching a comic series entitled MYSTIC POULTRY. Originally intended to promote our next show, we are instead opening up this collaborative art project to the masses to help combat quarantine madness. Ever wanted to write and/or illustrate a comic strip? This is your chance!

domain: artistic


Despite the threats of deportation and the thinly veiled racism, Hispanics in the U.S. remain confident and resilient in their communities. Welcome to the real American Dream.
Myths about Trump’s victory in Florida persist. Will the false narrative of Cuban-American voters shape the anticipated changes to U.S.-Cuba policy?
Let’s be clear: NATO isn’t encroaching in the hemisphere, nor does China represent a stable path out of dependency for Latin America. The former is a convenient, traditional boogey man and the latter an ahistorical pipe dream.
Craig Deare, who was recently named NSC’s Senior Director for Western Hemisphere Affairs, has been asked to leave the job, leaving a vacuum in Trump’s administration Latin American team.
If President Trump abandons the global fight against climate change, it could leave Latin America more vulnerable to the effects of climate change and governments politically exposed.
In a little noticed vote tied to the plans to overturn the Dodd-Frank Act, the U.S. Senate voted to overturn restrictions on bribes that U.S. resource extraction companies can pay to foreign governments.
Here’s how much it would cost the U.S. government and taxpayers to deport the 11.3 million undocumented immigrants that President Trump has targeted.
Here is the text of the written answers on U.S. policy toward Latin America and the Caribbean Rex Tillerson submitted to the Senate for his confirmation hearing. The answers cover Mexico, the Colombia peace process, the opening to Cuba and human rights, and political prisoners in Venezuela, among other topics.
In a new series, different authors will look at President Trump’s promises and proposed policies that will affect Latin America and Hispanics: their possibility of being adopted and their impact. First up: re-negotiating NAFTA.
False news has become the new claim to discredit anything that you don’t agree with. Here Rep. Lamar Smith smeared a correct interpretation of an honest, factual report that he misinterpreted as “fake news.”


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Judge Rejects Bid for Nationwide USPS Rule on Mail-in Ballots
- Advocacy group sought national policy for ballot delivery
- USPS reduced extra, late trips in July, which slowed service
The U.S. Postal Service doesn’t need to enact a nationwide policy to speed the delivery of voters’ ballots in individual state elections, a federal district court in Washington said.
The U.S. District Court for the District of Columbia on Tuesday deferred to the service’s district managers to determine how to ensure ballots are delivered in a timely way in state elections. Judge Emmet G. Sullivan declined to order the service to enact changes that voter advocacy group Vote Forward sought.

domain: news


Toyota TES-ERA EV Car Concept at the 2012 Tokyo Auto Salon, the world’s most significant custom car show, the particular Toyota Engineering Society unveiled a sporty looking little electric powered sports car. Referred to as the TES-ERA EV, the little coupe is actually powered by a 5.7 kWh lithium ion battery pack which products electricity to a 4JM electric motor developing 164 horsepower as well as 247 lb-ft (335 Nm) of torque. The fiberglass bodywork in Toyota TES-ERA EV hides a space shape chassis and a height adjustable double wishbone suspension setup both front and rear. On the inside the particular car is fitted which has a customisable tablet PC acting as an instrument panel, it is furthermore equipped with a rear and side view camera keep track of system, and a new pair of sports seats complete with four-point harnesses. The fully-functioning Toyota TES-ERA EV concept capabilities a KERS system for recharging the batteries during braking, and also a plug-in charging socket which is suitable to use in most standard outlets. Toyota Engineering Society is a voluntary organization regarding Toyota Motor Corporation employees that consists mainly involving engineers. It was created to enhance the technical skills as well as talents of members, promote teamwork and friendship, as well as contribute to the development of new technologies and ideas. There are approximately 30,000 members worldwide.


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Schecter dating serial number
Between names, the company made the most of its remaining Fender Broadcaster decals by cutting off the word Broadcaster so that only the Fender brand made it onto the guitar’s headstock. Only about 60 Nocasters were made, which makes them extremely collectible, but by April of 1951 the guitar would finally get a name that would stick, the Telecaster. Unlike the Telecaster, whose ash body was outlined with rib-digging 45-degree edges, the Strat had a sculpted body that fit players like a glove.
Three pickups gave the instrument unprecedented tonal range, as did a vibrato bar that would bend the guitar’s strings when pressed.
Just take a look at the albums whose musicians thought enough of their Fender guitar to put it on the cover: Eric Clapton’s "Layla," Bruce Springsteen’s "Born To Run," Jeff Beck’s "Wired," The Pretenders’s (Chrissie Hynde) "Get Close," Bonnie Raitt’s "Nick of Time." The list of influential artists who play a Fender is just about endless.
Fender’s first solid-body electric guitar was introduced in 1950.
If the guitar has been altered, it can depreciate the value of the guitar tremendously.
If you are having trouble finding the date of the guitar you are researching, try emailing the manufacturer and see if they can help date the instrument.
The newer model mirrors every detail of its original counterpart with a few modern upgrades that were introduced in 2013 with Gibson's Custom 20th Anniversary Specifications.
1980-1997 Originally, numbers of the form GXXXXXX were used for guitars and numbers of the form BXXXXXX were used for basses.Guitar dating services provide serial numbers to date your guitar.Below we have listings of guitar dating and serial number information sites and other resources.Some of those include variables such as refinished bodies or necks, replaced parts, refrets, and overall condition of the guitar.Original and mint condition will catch the highest values for your instruments.

domain: hobby


Businesses who want a better future knows the importance of social networking. To reach more audience today, social networking is the real key that expands your business globally. But is it suitable for everyone? Due to increased global interactions, users and spending more time on the internet. To find any information today, we rely on the internet and we don’t find one, consumers to think that the company is not matching their expectations.
Statistics of the internet population:
Here is what the new statistic shows us about the increase in using social media and the internet population.
Competitions of social media platforms have been increased:
Even though everyone knows that Facebook is always on the top but the new research says that YouTube in the future is going to give a tough time to everyone. Still, most of the sales are now done through social media platforms. Therefore, social networking is now important if you want to reach out to your customers. People spend more time on their phone rather going out and find the products. So, we can say that it has become an addiction too for people as they now rely on the internet and social media for everything.
Social networking has increased brand visibility:
Without a doubt, brand visibility or its image in the mind of consumers is everything. If the users don’t know you, you might want to pack up your business. The social media works as an effective solution if you are using the right strategies. The debate that whether we are using social networking right or not depends upon the strategies we are using.
People might consider that through some running ads, brands make enough money. But, that’s just not it. Many businesses are hiring today social media marketers to help them out as leading their pages online and running successful social networking is not just simple.
You might want to pick out the best social media platforms for effective communication with your consumers. If you are targeting globally, then you must be sure about the language barrier. Sometimes the needs and values of other cultures and countries can be different and you really have to make sure that you are providing the best to them.
Every content should be monetized and go through the necessary measurements to make sure that the users love it. As your communication depends upon it every time. If you don’t know how to handle then its time to bring someone on board as today the professionals know better. In fact, they will be able to provide better results and you can rest assured that your social networking is in good hands.


Starting May 4th 2020 and every Monday in May our amazing guests will be helping us recap food, fodder and fare!
Starting May 6th and every Monday in May our amazing guests will be helping us recap murder, misdeeds and mayhem.
Theory of Obscurity: A Film About the Residents. This film peels back some of the mysterious layers surrounding the San Francisco experimental music entity.
It’s Doc Time! We all have that family member where you probably shouldn’t bring up anything that’s happened in the past two years at dinner, but you love each other in silence. As you stare…
Restrepo is a 2010 American documentary film about the Afghanistan war, directed by American journalist Sebastian Junger and British photojournalist Tim Hetherington.The film explores the year that Junger and Hetherington spent in Afghanistan on assignment for…
George spoke with Eric Steuer about one of his favorite docs, EXIT THROUGH THE GIFT SHOP (2010). The only film credited to Banksy, Exit Through The Gift Shop tells the story of Thierry Guetta, a self-taught street artist/documentarian who ends up becoming the subject of the film.
Sup Doc is a great idea for a podcast series – interviews with interesting people about their favorite documentaries. The latest episode is with Wayne Fedeman, who discusses Terry Zwigoff’s documentary about cartoonist Robert Crumb. If I had to pick a favorite documentary, it would be Crumb.
Our FIRST episode! If you were a serial killer would you walk into a store and piss on some candy? We’ll discuss this and more when Paco and George welcome SF comedian and writer Matt Lieb to the show. In this episode we talk with Matt about the HBO 6 part documentary The Jinx. *SPOILERS* We also discuss all of the weird and creepy stuff Robert Durst did, other clues and info not shown in the doc, and ask the question “Where is Morris Black’s head?”


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(The Mandolin by Alex Gross)
Arjan Writes has something from MTV approved Swedish group Carolina Liar.
Ultra Stimulation jumps on the very crowded TTA bandwagon, hold on tight it’s a bumpy ride.
The Yellow Stereo has a nice writeup of indie pop artist and promoter Jonna Lee.
Milk Milk Lemonade has the gnarly punk of Affordable Hybrid.


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Retrieved As with stars of rock and country music, almost every successful rapper today, from Jay Z to Future to Chance the Rapper, has at some point performed lyrics that objectify or exploit women. US Cash Box Top Namespaces Article Talk.
While Lead Belly's recording was also performed a cappella with hand claps in place of hammer blowsmost subsequent versions added guitar accompaniment.
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Retrieved 22 December Martenzie is an associate editor for The Undefeated. Irish Singles Chart. But Drake is as much a feminist as Rachel Dolezal is a black woman. Some sources claim it is one of Lead Belly's many adaptations of earlier folk material;  in this case an 18th-century marching cadence about a flintlock musket.


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Troubled family case studies
Supporting troubled families links families case studies supporting troubled families we are engaging our partner agencies to enable a whole family. Supporting troubled families wider support and resources, both for families and services in general family intervention project practice guide. Case study drug and alcohol rehabilitation: teen challenge, kazakhstan douglas boyle1 family member’s addiction and the effect it has had on all those associated. Case study: troubled families the case study which follows describes where a data management layer facilitated by agility databroker has been introduced to a local. Family case study 6 family composition and history: wwwhantsgovuk/supporting-troubled-families hampshire’s supporting families programme the outcome.
Family action is a leading provider of home-based family support services for vulnerable and disadvantaged families we have a strong track record of working. Detailed case studies of how four local authorities are involving youth workers in the delivery of the troubled families programme case studies of nya. Troubled families - a case study the family supporting families plan address emma's mental health, anxiety and parenting skills ensure families are receiving correct. The troubled families agenda - what does what is a ‘troubled family 6 read more at wwwnatcenacuk/study/families--children-study 7 transcript: troubled.
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Family out of the area by smashing windows in the property activity with the family julie and sonia were very mistrustful of troubled families: case studies. ‘troubled families’ programme in england: ‘wicked problems’ and troubled’ families programme in england can inform and family case studies. The troubled families programme is being delivered learning points from each case study each troubled family is different and this has been.
Case study: willie willie is a ten-year old, with severe hemophilia and a troubled family background he has shown certain aggressive tendencies almost since birth. A family case analysis presented to the college of nursing family case study family case study iii_a family case analysis family case study. Case studies of families involved with welfare and child welfare in: family, and environmental factors which contribute to abuse. Aipc’s case study collection edition 1, 2007 enjoy your reading and feel free to forward aipc’s case study collection 2007 to family, friends and colleagues.
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domain: sociology


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Brussel sprouts are my all time favorite autumn vegetable, so I cook them any chance I get. My favorite way to prepare them is to roast them in the oven. Not only is roasting them a great way to extract flavor, its also quite easy and time efficient.
I start by preheating the oven to 400 degrees. I like to slice them in half, so they cook evenly and fully through (sliced shallots or onions are also optional for extra flavor.) The next step is to lightly toss them in olive oil, salt, cumin, and black pepper and spread them across a baking sheet. Depending on the oven, they usually cook for about 20-25 minutes, or until they are golden brown on the edges. The smells from the oven are sensational and make me feel fully submersed into fall.
The brussel sprouts can either be served as is, or you could toss them with an aged balsamic vinegar for a sweeter flavor.

domain: food


Contents (1998 - 86)Skip to content
Workplace Injury Management and Workers Compensation Act 1998 No 86
Current version for 22 November 2019 to date (accessed 8 July 2020 at 02:53)
270 Obligations of worker to provide authorisations and medical evidence
(1) An insurer who commences weekly payments of compensation under this Division may require the worker to provide the insurer with—(a) a medical certificate certifying as to the worker’s incapacity for work, and(b) a form of authority signed by the worker authorising a provider of medical or related treatment, hospital treatment or workplace rehabilitation services to the worker in connection with the injury to give the insurer information regarding the treatment or service provided or the worker’s medical condition or treatment relevant to the injury.(2) The insurer may discontinue weekly payments of compensation under this Division if the worker fails to comply with a requirement under this section within 7 days after it is communicated to the worker by the insurer.Note.This section does not limit the obligations of a worker under section 44B (Evidence as to work capacity) of the 1987 Act.


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On the day of Baby's Chalazion eye surgery, we had lunch at Little Penang Cafe. This cafe is located just below ISEC. Here's what we had and for you to drool on :D
Sinfully refreshing and fattening ice-kacang with banana slices, roasted peanuts, sweetened sweet corn, jelly, evaporated milk and 'sarsi' flavored syrup.
Delish nasi lemak. The coconut milk cooked rice was really fluffy and fragrant. Even someone who is on a low-carb diet cannot resist chomping down a few spoonfuls of the rice.
Pai Tee (Top Hat) - very good. The 'hat' was very crispy and had no rancid taste. The braised turnip was sweet.
The famous Penang char koay teow with large prawns and crab meat, yums!!
Every plate of food on the table was wiped off within minutes as both the hubs and I were famished after 'fasting' with Baby for the whole morning.


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Faversham launches its first app. After months of planning and software development with Savvy UK, Faversham Business Partnership are delighted to be able to launch the Faversham Reward app.
All Faversham Reward cardholders can now download the app on to their smartphone/tablet to view participating businesses, see their point tally and special offers. The app displays a map of Faversham with pins denoting where the Faversham Reward businesses are located.
If you are not a Faversham Rewards cardholder, you can purchase a Rewards Card from the participating businesses for £5.
Faversham Rewards is in its sixth successful year, with over 4,000 cardholders. All details of participating businesses can be found at www.faversham.org/rewards
There are two levels of businesses that are part of the scheme.
Currently 16 businesses are part of the popular point collection scheme, which enables card users to accumulate points to receive a voucher which gives them discount against a future in-store purchase. And 10 local businesses offer cardholders a point of sale % discount, or free drink as a way of saying thank you. All the businesses will feature on the app ensuring that cardholders can easily see who is part of Faversham Rewards and what they are offering.
Businesses will be able to host special offers on-line which can be easily added and edited, a further benefit to the all new Faversham Rewards.
"With this new exciting addition to Faversham Rewards we hope more businesses will benefit, more businesses will join the scheme, and furthermore cardholders will enjoy using the app which also has important links to www.faversham.org the area's directory of everything you need to know."
QR code to take you to the app


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DENVER — On Thursday, the U.S. Supreme Court handed down a ruling that significantly limits the Environmental Protection Agency's ability to regulate greenhouse gas emissions from power plants.
Justices ruled 6-3 that the Clean Air Act does not give the agency broad regulatory powers for reducing emissions. Instead, the majority opinion said Congress must specifically authorize agencies to make these types of rulings that are considered transformational to the economy.
“In some ways, they are turning to Congress to be more active, despite the fact that everybody knows Congress is not really capable of doing that,” said Jonathan Skinner-Thompson, a law professor at the University of Colorado in Boulder.
Skinner-Thompson knows a lot about the federal clean energy rules because he helped craft them under both the Obama and Trump administrations. Before accepting a job with CU, Skinnter-Thompson worked for the EPA in the Office of General Counsel in the Air and Radiation Law Office, which handed all of the agencies air regulations.
“I actually helped draft the legal interpretation that was the key part of the Clean Power Plan. I was detailed to the Department of Justice to help defend it,” he said.
He also wrote part of the brief in the DC Circuit and was assigned to the Solicitor General’s Office in its defense.
Under the Obama administration, the Clean Power Plan took a broad interpretation of Section 111 of the Clean Air Act and authorized the EPA to determine the best systems of emission reduction. It’s broad, somewhat vague language.
“The CPP interpreted that phrase — the system of emission reduction — to mean anything, any measures that power plants, that their owners or operators can do to reduce emissions,” Skinner-Thompson said.
It did that with a three-part plan — heat rate improvements to make power plants run more efficiently, shifting power generation away from coal power plants to gas-fired plants and then eventually shift away from all fossil fuel-fired power plants to renewable energy.
Under that framework, the EPA came up with emissions reduction targets for states to meet, and it accommodated a cap-and-trade system. States could meet their carbon limits requirements by relying less on coal plants.
When the Trump administration took over, it repealed the Obama-era rules — though they had already been put on hold by the Supreme Court in 2016 — and instituted a much narrower set of rules.
Because he was a career attorney, Skinner-Thompson helped repeal CPP and then craft the Affordable Clean Energy rule.
“It said instead what Section 111 authorizes, what "best system of emission reduction" means is only things that you can do to physically improve the emissions or reduce the emissions at the source. This has been called the fence line argument,” Skinner-Thompson said. “Basically, you can't shift generation away from one coal-fired power plant to a gas-fired power plant or to new renewable energy sources. All you can do is reduce the emissions at the plant itself.”
The Trump administration then decided that the best system for coal-fired plants was to only make them run more efficiently. Critics of the idea argued that can actually increase emissions at those plants.
The Trump administration's interpretation of this ruling was also the subject of a lawsuit from dozens of states and paused by courts. The Biden administration has not yet adopted either approach.
Nevertheless, the justices ruled under the major questions doctrine that no agency can adopt rules to regulate an issue of major national significance without the express approval of Congress. Several conservative justices have spoken out about the unchecked powers of federal agencies. This ruling requires a more narrow view of the Clean Air Act.
However, even without these EPA rules, the country has already exceeded some of the emissions goals set out by the Obama administration, and even moved beyond them.
“You have a lot of these agreements between [public utility commissions] and companies to help clean the electricity generation fleet, and so they're voluntarily moving forward regardless of what's happening at the EPA,” Skinner-Thompson said. “By the time EPA comes out with a new rulemaking, it's possible, at least for most of the power sector, that that's largely moot.”
Congress could decide to allow the EPA to come up with tighter rules around emissions. In the 90s, the agency passed an amendment to the Clean Air Act to establish a cap-and-trade program for power plants to address acid rain, for example. However, with the current gridlock on Capitol Hill, a change in this area is unlikely.
“It is a disappointment. I think for those of us who are hoping that EPA could take aggressive and significant action to address climate change, in particular greenhouse gas emissions, CO2 emissions from power plant, we're not going to see that,” Skinner-Thompson said.
Environmental advocates called the Supreme Court's decision catastrophic and disastrous for the fight against climate change.
“What it means is that Colorado has to find a way to fill in that gap that the EPA is going to leave. The federal government is taking a step back today,” said George Marlin, a Clear Creek County commissioner and the president of Colorado Communities for Climate Action.
Marlin says his area is already seeing the effects of climate change with shorter rafting seasons and greater wildfire risk. The area’s economy relies heavily on tourism. He warns that the issue is not going to fix itself, and that it will take many local and state governments to come together to address the gaps the Supreme Court's decision creates.
However, for states like Colorado that have already passed robust laws aimed at curbing the effects of climate change, little is likely to change with this ruling.
“Colorado has already enacted a number of climate strategies that has its own greenhouse gas map,” said Stan Dempsey, president of the Colorado Mining Association.
Part of those goals include the closure of coal-fired power plants by 2031. Dempsey says those decisions are already well underway and irreversible.
“In Colorado, we are showing the nation how cost savings from clean energy is rapidly reducing pollution, saving people money and creating jobs. Colorado utilities are already on a path to meet or exceed 80% renewable energy by 2030. We are fighting for a cleaner, healthier community,” a statement from Governor Jared Polis said.
Dempsey doesn’t see this Supreme Court case as one about the climate, but one about agency overreach and a legal issue about who can regulate what. He insists that people in his industry are not dancing with joy over the ruling because they are committed to addressing climate issues with policy makers on a state and federal level.
The Supreme Court ruling could have far-reaching impacts on government agencies. For now, the burden is on states to determine how to address the impacts of climate change.

domain: law


WORK COAT - ECRU
A durable outerwear staple to take you through the seasons, our hand-dyed work coat features triple-needle stitch on its main seams and four single-needle patch pockets and riveted buttons for a utilitarian look.
Made by Riverside Tool & Dye in Philadelphia
CONTENT & CARE:
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MEASUREMENTS (taken from size medium):
Length - 29”, Width pit to pit - 21.5”


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Buying online is less reliable still because there’s no regulation or standardization. What you see on the label may not be what you are getting. A 2017 study in JAMA found that of the 84 CBD products researchers bought online, 43 percent had more CBD than indicated, while 26 percent had less, and some had unexpected THC.“There’s a 75 percent chance of getting a product where the CBD is mislabeled,” says Marcu, one of the study’s coauthors.
CBD oil has become increasingly popular and accepted in the mainstream in recent years, but there are still laws and regulations that must be followed. By having a better understanding of the laws that govern cannabidiol oil both in the U.S. and abroad, online merchants can avoid any regulatory issues and grow their businesses in a safe, legal way.
If you’re dealing with depression, whether or not its related to your weight issues, working out and eating better are certainly ways to improve your mood. If you need an extra lift to get out of that rut, CBD is a known anti-depressant. While it relieves pain and inflammation, it can also relieve anxiety and help you see the brighter side of things.
At least one in six Americans is dealing with weight loss issues and many more than that spend time worrying about their weight. As we’ve learned over the years fad diets, cleanses, and shortcuts won’t get you anything but a trip to the hospital. However, adding an extract like CBD oil for weight loss can be a big help to supplement healthy habits and better choices.
Hemp-based CBD oil is NOT, I repeat, is NOT the same as raw oil produced from the whole marijuana plant. I’m getting so sick and tired of the marketing out there, I could scream. Cannabidiol from marijuana plants contains THC-A, which is not intoxicating — heating it will convert it to THC-C. This is how large amounts of THC-A can be consumed — the oil from raw marijuana plants has a higher safety profile, too. Once this market is REGULATED (and it will be), there will be very clear distinctions. At the moment, it’s up to the consumer to do his/her homework. Until then, please don’t fall for some of this marketing. Sure, Hemp CBD oil can be useful, but people are being duped into thinking it’s the same thing with the same benefits. IT IS NOT!
If people would get as involved with such deep investigation into their own human growth and potential rather than getting into arguments about what part of a plant a chemical comes from then this world would truly be a happier place and better for our children. Come on people be nice to eachother, do some deep spiritual healing without drugs. Use plants for healing instead of “not dealing with your own issues” hypnotherapy is side effect free and has permanent results
A 2016 study in Molecular and Cellular Biochemistry explored how CBD contributed to the fat browning process. Brown fat is a particular type of fat that works to increase energy expenditure, and it produces heat. This allows brown fat to burn more calories, but adults are mostly composed of white fat. In the study, the following was observed as a result of cannabinoid usage:
Hemp derived CBD oil with a THC level OVER 3% is legal in Canada with a prescription, from a licensed supplier or dispensary. CBD oil with a THC level BELOW .3% is legal in Canada, for personal use only, without a prescription. However, it is not approved for resale without an NPN from Health Canada. So you can NOT sell it, unless they have a number. So... if you want it without a prescription... you have to import it from a US company. I like this one...
As you can see, while it is from a technical standpoint illegal to mail CBD oil, it hardly seems to be an issue that is being enforced. Case in point, dozens of firms across the U.S. are selling and shipping thousands of bottles of CBD oil every single day, and we have yet to hear of a single instance where a company (or individual) has been arrested on federal charges.
If you answered “yes” to step 2. Talk to your doctor as there are several ways you can avoid CBD interacting with your prescription medication. Even high doses of CBD often cause little to no issues due to body chemistry. By monitoring with regular blood tests, even if CBD inhibits too many CYP enzymes, side effects can be prevented by catching the interaction before any harm occurs.

domain: health


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Unleash Your Inner-Pimp: Overcoming Shyness
In most cultures, American especially, being considered shy is not a positive trait.
Shyness is seen as a weakness; something that holds people back from displaying their most attractive personality and leading fulfilling relationships, whether personal or professional.
Shyness itself is described by feelings of apprehension, lack of comfort, or awkwardness experienced when a person is approaching/being approached by other people, especially in new situations or with unfamiliar people.
According to respected fashion designer Tom Ford,
“You should put on the best version of yourself when you go out in the world because that is a show of respect to the other people around you.”
Those that are shy walk on eggshells scared, anxious, fearful, worried…this is not a persons’ best and it’s a mediocre way to live life.
Unfortunately, media perpetuates the idea that mediocrity is acceptable. That a man can be shy around women, yet somehow via Disney fairytale magic, he eventually lands the babe…in the end. Really?
I used to believe the television shows and movies. Additionally, I also read the dating advice columns in popular mens magazines on the subject of overcoming shyness to approach women. I thought being shy was fine, just as long as I was “being myself” and “being confident”; then girls would have like me, right? Oh yea, I also memorized the most clever pickup lines thinking that would help too. Thing is, NONE of these resources addressed exactly how to “be myself” and “be confident”, or what it even meant, or how it actually worked.
The real truth?
Shyness is unattractive. Again, it’s a mediocre way to live life because it’s not a persons’ best. Living with shyness is unacceptable if a man wants to successfully approach the beautiful women he’s attracted to. Period.
Yes, I could’ve continued to accept mediocrity and hoped my situation got better. Perhaps I could’ve gotten “lucky”, and waited for the girl of my dreams to magically find me. If this sounds acceptable to you, then please go to the upper right hand corner of this screen and click X. This article is not for you.
The next section reveals how and what I did to remedy my shyness: Unleashing my inner-pimp and transforming from a man overwhelmed by shyness to a man that confidently approaches the women he’s attracted to…
Unleash Your Inner-Pimp: Overcoming Shyness
Do Not Care What Others Think Or Say About You
When you care, you’re reacting to others, seeking approval. You teeter on eggshells, feeling uncomfortable, intimidated, insecure and confused about what to say/do. Be your own person, live your own life. Do what you want, and others do what they can about it.
As an exercise, chant this yourself right now- “I do NOT give a damn…what anyone thinks about me”. Do this as much as you’d like, til you feel a physiological sensation and your voice sparkles a 100% belief that you honestly do not care what ANYONE thinks about you.
You Do Not Need Anyone Else To Make You Feel Good About Yourself
If you’re looking for someone elses’ validation (especially a girls’), then you’re being a bitch. And you will never be attractive; no girl will ever be attracted to a man she feels sorry for. As a man, acknowledge that there is nothing someone can give you that you can’t get for yourself.
You, And ONLY You, Can Control How You Feel About Yourself
Be cognizant how you FEEL in relation to the world around you, not self-conscious. Don’t take yourself or the world too seriously; find humor in everyday life, draw inspiration, cultivate a love for being. Monitor your thoughts and examine the role it plays in constructing the beliefs about yourself. You are what you believe.
Give Yourself PERMISSION To Be The Man You Want To Become
List the traits of the ‘ideal’ man you wish to be. Understand those traits and shift your behavior towards becoming THAT person. Now the blueprint is now there to follow. Think to yourself: How would my ideal self react to a situation? Give yourself permission to act accordingly!
You’re Either Confident Or You’re A Bitch
You cannot be ‘almost confident’ or 99% confident. Confidence, as I understand it, is purely the absence of fear. Nothing is holding you back; no mental obstacles between you and what you want. Notice how a five year old can be just as confident as a corporate CEO; just because they don’t have a care in the world and no mental obstacle holding them back.
Visualize yourself as a boom-box exploding awesome music (self-expression), radiating good vibes and being the life of the party. Speak LOUDER by pushing the air from your stomach outwards, not the air from your throat. Remember too, everything you say is important; it is important because it’s coming from you.
I cannot vouch enough how helpful this was for my own development. By joining Toastmasters, you are forced to speak to a public audience and you will receive honest, encouraging feedback towards sounding/appearing more confident. Click here to find a club near you.
Frequent masturbation is linked to increased social anxiety that detaches men from becoming outgoing, energetic, and having fulfilling interactions. If there’s one destructive habit that destroys the motivation for men to approach women, it’s masturbation..
Join a GYM, develop good posture. The mind follows the body! Enhance your style and have women take notice of you…for the right reasons.
Be proactive. Be a man and take charge. You + Taking Action= your best self.
The richer your life is, the more confident you should feel about yourself.
Girls Are Attracted To Confidence
For a woman, a highly confident man (regardless of looks, money, status) is the equivalent of a Sports Illustrated swimsuit model for men.
Simply, Confidence = Attractive.
Let’s be real though. A women isn’t going to pick herself up. It’s a man’s responsibility to approach beautiful women…just don’t let shyness (living in mediocrity) stop you.

domain: psychology


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Kansas lost forward Carlton Bragg this offseason after a pretty tumultuous career in Lawrence. The 6'10", 240-pound power forward was suspended twice in his two seasons on campus and never got the playing time he hoped for. He announced his transfer earlier in the month and now has a top list of schools of where he might go.
RELATED: Carlton Bragg to transfer
He drew a one-game suspension in December after an incident in which he was charged with misdemeanor battery for allegedly pushing a woman down a flight of stairs. The charge was dismissed when video evidence displayed he acted in self-defense.
Bragg was suspended three games in January for a violation of team rules. He was charged with misdemeanor possession of drug paraphernalia and was later granted a diversion agreement to settle the charge.
Bragg averaged 4.4 points, 3.2 rebounds and 0.3 blocks per game in his two seasons at Kansas after the Jayhawks won his services in a huge recruiting battle in the summer of 2015.
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This week, let's continue our study of Shakespeare's great tragedies with the Play That Must Not Be Named, aka the Scottish Play, the Bard's play and Mackers. Actually, I'm not in a theater at the moment, so it's okay to say that your reading for this week is Macbeth.
As always, we'll start the discussion at noon next Sunday. In the meantime, if you want a funny take on the alleged Macbeth curse, pick up the second season of "Slings and Arrows," a Canadian series based on the Stratford Shakespeare Festival. It's all fun and games until someone mocks the Macbeth curse and promptly falls off the stage and breaks her neck.


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Erste Group has posted an EUR 262.2 mln net profit in the first quarter of 2017. According to group, the performance was supported by the healthy macroeconomic environment across CEE and the continuation of last year’s positive trends.
Specifically, lending volumes grew at a stable level especially in retail banking, risk costs remained historically low, asset quality remained very solid with a NPL ratio below five percent, allowing the group to and to maintain a high level of capitalization, with a core tier one capital ratio (phased-in) of 13.0 percent.
Cost base rose during the first quarter, partly reflecting spending needed to address regulatory requirements, but mainly driven by investments in further expanding the services they can offer digitally to customers.
“We’re pleased that our performance was also recently acknowledged by rating agencies, with Standard and Poor’s and Fitch raising our long-term ratings to A- (Positive) and A- (Stable), respectively. The trends that we see at the Group level are also reflected locally: all our subsidiaries had a profitable first quarter in 2017,” said Andreas Treichl, CEO of Erste Group Bank AG.
In the interim management report, financial results from January-March 2017 are compared with those from January-March 2016 and balance sheet positions as of 31 March 2017 with those as of 31 December 2016.


WEATHER UPDATE — According to the Philippine Atmospheric, Geophysical, and Astronomical Services Administration (PAGASA), the Low-Pressure Area (LPA) being monitored has been spotted 140 km east of Hinatuan, Surigao del Sur. The LPA will remain stationary before moving northwards over the weekend.
The weather agency reports the LPA has a wide circulation, bringing rain to Southern Luzon, Visayas, and parts of Mindanao.
Today, the LPA is almost stationary over southern Mindanao. However, due to its broad circulation, it will move somewhere between Visayas and Mindanao on Saturday. Then, on Sunday, it will move further north, between the Bicol Region and Visayas.
On Monday, the LPA may disperse due to the Northeast Monsoon.
Meanwhile, the shear line continues to strengthen the rains brought by the LPA, especially in Eastern Visayas and the Bicol Region. It will continue until Monday or when the LPA disperses.
The Northeast Monsoon, or Amihan, also continues to bring light rains over central Luzon and isolated rain showers over the rest of Luzon.
WEATHER TODAY – JANUARY 13, 2023
For today’s weather forecast, areas in the Bicol Region, specially Albay, Sorsogon, Masbate, Catanduanes, and Romblon, will experience moderate to, at times, heavy rains due to the LPA.
Camarines Provinces, the rest of Mimaropa, and Quezon Provinces are forecast to have cloudy skies with isolated rain showers and thunderstorms brought by the LPA and shear line.
The rest of Luzon, such as Cagayan Valley, Aurora, Calabarzon, and Metro Manila, is forecast to have cloudy skies due to the Northeast Monsoon. Areas in central Luzon, including Ilocos and CAR, may expect the same weather conditions as yesterday, with light isolated rainshowers.
Residents in Eastern and Central Visayas are warned of flash floods and landslides due to the Low-Pressure Area. Heavy rainfall warnings may be issued within the day.
PAGASA also reminds the public that Orange and Red rainfall warnings mean automatic suspension of classes.
On the other hand, the northern portion of Mindanao, including the Zamboanga Peninsula, Northern Mindanao, Caraga Region, Dinagat Islands, and Surigao del Norte, continue to be affected by the LPA. Though there will be less rain than in the previous days, residents are still warned of flash floods and landslides.
The rest of Mindanao, such as the Bangsamoro Region and Davao Region, is forecast to have cloudy skies in the morning and localized thunderstorms by the evening.
PAGASA continues to issue a gale warning to areas in Luzon and Eastern Visayas. Waves are expected to reach up to 4.5 meters. See the full list below:
- Eastern coast of Cagayan
- Northern Quezon, including northern and the Polillo Islands
- Camarines Norte
- Northern coast of Camarines Sur
- Northern and Estern coast of Catanduanes
- Eastern coast of Albay
- Eastern coast of Sorsogon
- Northern Samar
- Eastern Samar
- Eastern coast of Southern Leyte
- Dinagat Islands
- Eastern coast of Surigao del Norte
Watch the 5 am weather update today below:


Win at Helix gives Warriors first field hockey win over San Diego Section team
Last updated 9/16/2022 at 3:51pm
Village News Reporter
Fallbrook High School’s field hockey team began the 2022 season with a 1‑2 record, and the win was against Great Oak, which is in the CIF Southern Section. The Warriors then traveled to Helix for a Sept. 6 match, and a 1-0 win gave Fallbrook the team’s first victory this season against a CIF San Diego Section opponent.
“They did great,” said Fallbrook coach Debbie Berg.
Each field hockey team has 11 players on the field at a time. Fallbrook’s varsity roster consists of 14 girls. Two of the players were ill Sept. 6 and Mallory Sehnert missed the...


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This should be applied in everyday circumstances!
Loving Life and Inspiring Others
A Thought, A Life, A Lady Enamor.
Its a Zimbabwean thing...
Eat and don't worry about it
The official page of the artist created to host the project 'CUT OFF'.
There's a hip grandparent in all of us!
through the darkness there is light
Empowering YOU With The ARTS
Optimism, Love, and Lots of Sass.


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LONG BEACH, Calif. -- The Long Beach State 49ers raced past the California State University, Los Angeles Golden Eagles for a 95-59 victory in their season opener Friday night in Long Beach. The 49ers are the favorites to win the Big West Conference and their display against the Eagles confirms the preseason selection.
Leading the way for The Beach was point guard Justin Bibbins, who filled the score sheet with 12 points, seven rebounds, six assists, and four steals. Bibbins was a Second Team All-Conference selection a season ago.
"Justin is an elite player in this league," said Coach Dan Monson. "He can play with anybody in this country. We're going to give him an opportunity to go prove it."
Over the past seven seasons, Long Beach State has ranked no lower than sixth in the nation in non-conference strength of schedule, according to Ken Pomeroy's ratings. The 49ers will immediately go on the road to play four teams who played in the NCAA tournament last year; they have Wichita State, No. 6 North Carolina, No. 14 Louisville, and No. 20 UCLA.
"We needed some confidence to buy into what works," said Monson. "Now we're going to get tested. They need to know what it's like to be at that level. That's the level we want to be, at the end of the season. No matter what happens, we're going to come back a better basketball team at the end of this week and that's why we play this schedule."
Friday night was the first time the two schools played each other since the 1992 season. Cal State L.A. was essentially a tune up for Long Beach State. The up-tempo style employed by Monson's team made it hard for the Eagles to keep up with. The 49ers continued to pound the ball inside and attack the rim; Long Beach State dominated the Points in Paint category 52-18.
Defensively, the 49ers applied pressure via the full-court press after made free throws and perimeter traps, which forced turnovers and resulted in easy transition points. Long Beach State led 51-38 at halftime and came out of the break turning up the pressure. One two-minute run of play featured Loyola Marymount transfer Evan Payne break away for three dunks to stretch the lead to 64-45 to put the game away. Payne was the game's high scorer with 15 points.
"I think [Payne] showed a level of comfort," said Monson. "He's been so locked-in to try to do what we ask of him defensively, he hasn't been comfortable on offense. Today he got out in the open court. He's as good as any player I have had in the open court."
The contributions from the visitors were minimal, aside from a crowd-pleasing dunk from Desean Scott in the first quarter of the game that provided the crowd in arena with much-needed energy, and ironically fueled a 49er's run to close out the first half.
The 49ers had two other players score in double figures, forwards Yussuf Temidayo and Gabe Levin, with 12 and 11 points, respectively. Overall, Monson utilized 14 players in this game, with 10 of them playing at least 10 minutes. Long Beach State is going to need all hands on deck to come back from this road trip with positive results.


President Cyril Ramaphosa unveiled statues of former President Nelson Mandela in the Eastern Cape on 18 July 2023. (GCIS)
Driving through Mthatha is almost like driving through a war-torn country. The streets are filthy, buildings verging on collapse, roads riddled with potholes, the people in perpetual states of poverty and lawlessness.
So common is petty crime that people rarely react. If you think you are going to find any working services and traffic lights, think again.
People are so used to living without running water that when it does flow they consider themselves lucky.
The stench of raw sewage flowing down the streets is familiar.
It’s no wonder then that the region’s newspaper, Daily Dispatch, recently reported that auditor general Tsakani Maluleke flagged the King Sabata Dalindyebo local municipality as one of 10 local governments that are so broken that it’s about to fall into a state of paralysis.
Maluleke is quoted to have said the municipality has little control over its finances, could not carry out service delivery and was drowning in debt and without cash in reserve.
It was deplorable and almost laughable when President Cyril Ramaphosa unveiled statues of Nelson Mandela, one in Qunu and another in Mthatha, on his birthday.
What would the statesman have said? Would he have condoned this under his name? Or would he have told the president to first fix his hometown before invoking his name.
The government is yet to say how much it cost to commission the statues but no matter how much it spent, this would have made some difference in the lives of the people of Mthatha.
The excuse it made was that the statues would help attract tourism. We must call bullshit. Mthatha lies between Port St Johns and Coffee Bay.
If Ramaphosa, Oscar Mabuyane and his government were serious about tourism, the state of these breathtaking towns with their scenic beaches would be central to development.
On this Mandela Day we were reminded of Mandela’s 1993 address to Cosatu delegates: “If the ANC does to you what the apartheid government did to you, then you must do to the ANC what you did to the apartheid government.”


Chelsea will play Manchester City in the Carabao Cup final after overcoming an aggregate deficit to beat Tottenham on penalties at Stamford Bridge.
Trailing 1-0 from the first leg, Chelsea made a bright start and got their reward when
With Tottenham looking ragged in all departments, Chelsea took full advantage with a well-worked goal to take the aggregate lead. Cesar Azpilicueta laid the ball on a plate for Eden Hazard, who simply passed the ball into the corner of Gazzaniga's net.
Mauricio Pochettino's half time team talk had an almost immediate impact as Tottenham restored aggregate parity within five minutes of the restart. Danny Rose's cross was in a good area for Fernando Llorente, who stooped to head the ball into the net.
8 - Fernando Llorente has scored eight goals in his last five starts for Tottenham in all competitions. Deputy. pic.twitter.com/uDLvRpC8Iz— OptaJoe (@OptaJoe) January 24, 2019
It was a much more even match thereafter, although the best chances were still falling to Chelsea. Olivier Giroud raced through on goal but fluffed his lines, and Hazard missed a couple of chances to get his second of the day, so it went to penalties.
Both teams scored their first two penalties before Tottenham's Eric Dier blazed the ball over the crossbar and Jorginho gave Chelsea the advantage. Kepa's save from Lucas Moura gave the Blues match point, and David Luiz made no mistake, sending Chelsea to Wembley.
Key Talking Points
Whether Chelsea's players were responding to Maurizio Sarri's stinging criticism after their defeat at Arsenal, or whether they were simply raising their game for a big semi-final, we don't know. But in the first half they produced exactly the kind of performance Sarri wanted to see.
He questioned his players' mentality and motivation after that meek loss at the Emirates Stadium, but it was a completely different team which took to the field against Spurs.
7 - Since the start of last season, Chelsea’s Eden Hazard has been directly involved in seven goals in his eight League Cup games (4 goals, 3 assists). Talisman. pic.twitter.com/fxdo6G7MNZ— OptaJoe (@OptaJoe) January 24, 2019
In a way, Chelsea's performance proved Sarri's criticism right. This squad has always had the ability to produce brilliant performances, it is only their ability to do so on a regular basis which is in question. They must be at their very best to stand any chance against Manchester City in the final.
STAR MAN - N'Golo Kante
Obviously you could make a strong case for Hazard, but it was Kante who set the tempo with a dominant performance. He made Tottenham's midfielders look like schoolboys in the first half, and it was his goal which set Chelsea on their way.
N'Golo Kante just nutmegged 3 people with one shot, and scored.— Paddy Power (@paddypower) January 24, 2019
Give the man the Ballon d'Or FFS.
I’ll say it again about Kanté...— Alex Goldberg (@AlexGoldberg_) January 24, 2019
He’s Chelsea’s best scoring midfielder right now. Miles ahead of Kova & Jorginho in that category and is hitting it WAY cleaner than Barkley these days.
4 - N’Golo Kante has scored four goals in 30 apps for Chelsea in all competitions this season – as many as he netted in his previous three seasons in England combined (4 in 129 apps). Upturn.— OptaJoe (@OptaJoe) January 24, 2019
WORST PLAYER - Olivier Giroud
With three talismanic forward players missing - Harry Kane and Dele Alli injured, Son Heung-min at the Asian Cup - Tottenham's night was always going to be about keeping it tight and taking their chances on the counter-attack.
But the absence of those three players seemed to have had an effect on the whole team, at least in the first half. Tottenham were overrun in midfield, with Harry Winks
STAR MAN - Danny Rose
Brought on as a first-half replacement for Ben Davies, Rose was a constant nuisance for Chelsea. He produced the cross from which Llorente scored, and continued to cause Azpilicueta problems, with the Spaniard going in the book for taking out his opponent.
Baffles me how Davies has been Tottenham’s first choice left back for a while, for me Danny rose is one of the best left backs in the world— Charlie Gleisinger (@Gleisinger) January 24, 2019
Danny rose yet again was brilliant— Dazza (@DazJudge1) January 24, 2019


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Build and breed, enjoy the adventure. Creatures of Olympus is a management game set in the Ancient Greece, a game where your task will be to create new creatures and feed all of the hybrids while building the best possible world for them.
Follow the game instructions and learn how the controls work, while getting familiar with the storyline.
Adventure in a distant land, take on enemies, and power-up your creatures.
Welcome to Creature Quest, where you’re given tiny monsters to take care of. Yet, you’ll soon find yourself using your monsters to battle different enemies including yetis and exploring the map to complete quests. Available for the iOS and Android, in battle, you’ll take on….
A fast-paced dungeon crawler with a retro style of play.
Hammer Bomb - Creepy Dungeons is a retro-style dungeon crawler where you must drop bombs and find treasures. As you make your way around the maze, you will find delicious snacks and uncover new perks and weapons. With easy controls and simple play, Hammer Bomb drops the hammer on dungeon cra….
Scoot the shirasu around the screen to discover creatures hidden beneath. THE VERICT
Well, this is weird. In Mysterious Creatures, you'll come face-to-face with an infinite pile of Japanese shirasu. Beneath the baby sardines is hidden a slew of little sea critters that presumably have also been caught in the net, like crabs and squid and so forth.….
A hidden object adventure. Hidden Object is a mysterious adventure series which will be extremely engaging for fans of apps where you need to pay attention and use your observational skills to find all the objects hidden in the scene.
The game features 25 impressive scenes with an awesome design and lots of items to find. Also, navigate between the….
A game that will entertain and inspire the imagination of young children.
Looking for a way to keep your kids entertained? Want to play together with your young child? Plum’s Creaturizer, the latest in PBS Kid’s ever-growing library of educational apps for kids, lets you and your child create wild creatures using body parts of hundeds of animals.….
Combine animals to create new creatures. Doodle Creatures is a curious puzzle game where this time, your job will be to create new species by mixing genes and discovering new and amazing creatures.
Tap on the different groups in order to expand them and follow the instructions so as to make the most of all the possible combinations. At first, the p….

domain: entertainment


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Data Availability StatementThe datasets generated during and analysed through the current study are available from the corresponding author on reasonable request. design included intra-assay analysis measuring accuracy, inter-assay analysis estimating methods linearity and precision and inter-assay analysis evaluating repeatability. Furthermore, in inter-operator analysis assessed the comparability of the result analysis of different operators. Staining stability was evaluated in age-of-stain experiments. Our validation results show that a reliable detection of residual myeloma cells is feasible to a detection level of 10?5 with a single-tube assay for a variety of materials (peripheral blood, bone marrow and stem cell apheresis). This study establishes highly sensitive, fully standardized approach for MRD detection in myeloma that is ready for implementation in routine diagnostic laboratories. Introduction Plasma cell myeloma is a hematologic neoplasm characterized by the proliferation of malignant plasma clones. With targeted therapies available, a considerable number of patients can achieve complete response and have a significantly better outcome, defined as increased progression free survival and overall survival1,2. However, only 3 to 10% of plasma cell myeloma patients who have received high dose therapy will remain in complete remission for more than ten years3, while the majority will eventually relapse and undergo further treatment. Since there is a correlation between Bufotalin the expand of response and extended survival, there’s an urgent dependence on extremely delicate assays for the recognition of minimal residual disease (MRD)4,5. MRD is certainly a more delicate way of measuring response than regular requirements and was proven to have a sophisticated predictive value compared to regular methods5. Thus, MRD recognition is vital for choosing whether an individual shall go through relapse-appropriate treatment2,6. Multiparameter movement cytometry enables solid and affordable monitoring of minimal residual disease7 in plasma cell myeloma sufferers. Due to the elevated number of concurrently used fluorochromes large selection of cells and subtypes with different features can be evaluated. This permits estimation from the MRD by differentiation and detection between normal and abnormal plasma FLJ34463 cells. For MRD assays to end up being particular and delicate extremely, a combined mix of immunophenotypic Bufotalin markers that can recognize and discriminate between regular and unusual plasma cells is certainly needed1,8C10. Compact disc38 and Compact disc138 were utilized as gating markers, while Compact disc19, Compact disc27, Compact disc45, Compact disc56, Compact disc81, Compact disc200 and Compact disc117 allowed for the id of the very most frequent deviation from the normal plasma cell phenotype. In addition, the presence of CD45 allowed for further phenotypic characterization of plasma cells and their quantification relative to the leukocyte count. In order to obtain a Bufotalin quantification limit (LOQ)11, defined as the lowest concentration at which the analyte can be quantified, in the magnitude of 10?5 (i.e. one abnormal plasma cell detected in a population of 100,000 leucocytes) the sample has to be enriched to a total leucocyte count of 3C5 million in a small volume (e.g. 100?l) following blood cell counting. The obtained cell suspension has to be stained according to a standard operating procedure (SOP)11,12. In this study, we present a highly sensitive and standardized procedure for assessing minimal residual disease in patients with plasma cell myeloma in peripheral blood, bone marrow as well as in apheresis product. Our results show that our assay due to its highly discriminative combination of antibodies and effective gating strategy can be easily applied and validated in high throughput flow cytometry laboratories. Materials and Methods Qualification of instruments and Bufotalin good manufacturing practice (GMP) training Qualification of all cytometers used in the study was preceded by risk analysis utilizing the Ishikawa (fishbone diagram) and risk mitigation technique performed based on Bufotalin failure settings and effects evaluation (FMEA)13. Furthermore, all cytometers underwent certification based on created SOPs. All techniques were referred to in SOPs as well as the specialized staff was effectively trained in utilizing the SOP Safeguard Software. Bloodstream and apheresis specimen collection The scholarly research was approved by the Ethics Committee from the Charit C Universit?tsmedizin, Berlin, Germany. All experiments were performed relative to relevant regulations and guidelines. Healthy plasma and people cell myeloma sufferers undergoing stem cell apheresis on the Charit C Universit?tsmedizin, Berlin, Germany were recruited because of this scholarly research. Written up to date consent was extracted from all individuals. Blood was gathered into vacutainers (BD, Heidelberg, Germany) formulated with EDTA for anticoagulation. Apheresis examples were collected using the Spectra Optia? Apheresis Program (Terumo BCT) utilizing the Continuous Mononuclear Cell Collection (CMNC) process. Myeloma cell range For the inter-assay evaluation the myeloma cell range U266 was utilized. This cell range was established through the.
Following periods of haematopoietic cell strain, such as for example after chemotherapy, radiotherapy, transplantation and infection, individual outcomes are from the degree of immune system reconstitution, of T cells specifically
Following periods of haematopoietic cell strain, such as for example after chemotherapy, radiotherapy, transplantation and infection, individual outcomes are from the degree of immune system reconstitution, of T cells specifically. TREC evaluation165. Significantly, thymosin-1 administration was also connected with elevated survival of sufferers with serious COVID-19 (ref.165). Sex steroid ablation Furthermore with their fundamental function in regulating sex dimorphism, sex human hormones can influence haematopoiesis at multiple amounts. Among the initial Snca observations relating to a romantic relationship between T cell advancement and sex human hormones goes back to 1898, when it was reported that this thymus enlarged after castration of male rabbits166. Several studies confirmed the enlargement of thymic tissue after L,L-Dityrosine hydrochloride gonadectomy in both sexes in different experimental animal models. Conversely, androgens and oestrogens induce atrophy of the thymus167,168. The increase in the levels of sex steroids, and in particular of androgens, during puberty has been directly linked to the age-associated deterioration of immune function and to the process of thymic involution. Although the connection between the increase in the levels of sex steroids after puberty and the initiation of thymic involution is still debated, the regenerative impact of the removal of sex steroids on both thymic and BM lymphopoiesis has been extensively characterized. Indeed, through the use of clinically relevant mouse models of immune reconstitution after haematopoietic injuries, such as chemotherapy and radiotherapy, it has been exhibited that sex steroid ablation enhances HSC self-renewal and lymphoid differentiation capacity and increases the number of common lymphoid progenitors in the BM169C171. Sex steroid ablation also has a direct effect around the BM microenvironment, L,L-Dityrosine hydrochloride restoring expression of key haematopoietic factors that are downregulated with age, such as L,L-Dityrosine hydrochloride FOXO1 (ref.169). Considerable rejuvenation effects in the thymus have been extensively characterized, demonstrating that sex steroid ablation reverses thymic atrophy, accelerates the recovery of all thymocyte subsets and elicits potent regenerative signals to the thymic stromal microenvironment55,172C174. At a molecular level, sex steroid ablation promotes the upregulation of the key thymopoietic factors CC-chemokine ligand 25 (CCL25)175 and DLL4 (ref.167) in mTECs and cTECs, respectively. Many medications have already been made to transiently and stop sex steroids for the treating precocious puberty reversibly, endometriosis, hormone-sensitive prostate breast and tumor cancers. A few of these sex steroid blockers have already been tested to improve immune system reconstitution after HCT clinically. A non-randomized pilot research confirmed that administration from the luteinizing hormone-releasing hormone (LHRH) agonist goserelin (Zoladex) before HCT considerably elevated neutrophil engraftment, aswell as total lymphocyte amounts, those of naive Compact disc4+ T cells especially, and degrees of TRECs and improved recovery of TCR repertoire variety176. Importantly, a rise in disease-free success was seen in autologous HCT recipients treated with goserelin. Two studies (“type”:”clinical-trial”,”attrs”:”text message”:”NCT01746849″,”term_id”:”NCT01746849″NCT01746849 and “type”:”clinical-trial”,”attrs”:”text message”:”NCT01338987″,”term_id”:”NCT01338987″NCT01338987) are ongoing to judge the effects from the LHRH agonist leuprolide (Leuprorelin) as well as the LHRH antagonist degarelix (Firmagon) to market immune system reconstitution pursuing allogeneic HCT. Notably, the most recent androgen receptor inhibitors and LHRH antagonists possess the benefit of instantly preventing sex steroids lacking any preliminary surge of sex steroids as noticed with LHRH agonists167. These novel approaches may provide better therapeutic tools to suppress sex steroids and mediate immune system reconstitution. The regenerative ramifications of sex steroid ablation on T cell advancement might continue just so long as the levels of sex steroids are suppressed. However, the duration of such effect, particularly in the setting of surgical castration, remains a subject of debate in the field. After the initial regrowth following castration, the thymus of aged animals has been reported to decline and return approximately to its pretherapy condition 1 month after sex steroid ablation therapy177. While these results support a model in which the regenerative effects induced after surgical sex steroid ablation are transitory and dynamic, additional studies should be done to better characterize the nature of these transient effects and the precise kinetics of thymic regeneration, in particular, at later time points. For example, it would be interesting to evaluate whether removal of the gonads, in the long term, can induce additional hormonal changes that negatively impact the process of lymphopoiesis. Growth hormone GH is a small peptide hormone secreted primarily in the bloodstream by somatotropic cells in the anterior pituitary gland178. Apart from its anabolic effects and impact on height, GH is implicated in the regulation of haematopoietic function also. Appearance of GH receptor (GHR), where GH.
High morbidity and mortality of diabetes mellitus (DM) throughout the human population is a serious threat which needs to be addressed cautiously
High morbidity and mortality of diabetes mellitus (DM) throughout the human population is a serious threat which needs to be addressed cautiously. DM and its related complications. 1. Introduction The diabetes mellitus (DM), one of the most prevalent noncommunicable disease, is usually characterized by hyperglycemia leading to the development of severe life-threatening complications [1, 2]. Recent decades have witnessed an abrupt boost of diabetes through the entire global globe, regardless of many efforts designed to control to outspread of the metabolic disorder. Presently, type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) will be the most widespread kind of diabetes. The T1DM, that is referred to as insulin-dependent DM also, is caused because of impairment in legislation of blood sugar by overall devastation of TNF-(TGF-(SDF-1 and insulin-producing. Within a scientific research, the synergistic administration of hyperbaric air and intrapancreatic autologous stem cell was effective in managing the metabolic degree of insulin in T2DM sufferers . It has additionally been shown which the preconditioning from the stem cell might enhance the efficiency of cell-based therapy. MSCs gathered from diabetic mice had been preconditioned in existence of insulin-like development aspect-1 (IGF-1) and fibroblast development aspect-2 (FGF-2) in moderate and were additional acclimatized under TPOR hypoxia and high blood sugar condition. After implantation of conditioned MSCs, the improvement in center condition of diabetic mice was noticed, indicating stem cell-based ways of treat diabetic center failure . Lately, coculture techniques are also utilized to improvise the efficiency of stem cells through improving their differentiation potential. In a scholarly study, the ESCs had been cocultured with hepatocytes and induced to differentiate into endodermal cells, that have been further induced to differentiate into pancreatic islet cells in existence of Matrigel and retinoid . Another experimental research demonstrated that differentiated islet cell clusters from CHK1-IN-3 individual Wharton’s jelly-derived mesenchymal stem cells in the current presence of rat pancreatic cells could suppress blood sugar level . Cotransplantation of kidney-derived MSCs with islets in diabetic mice in addition has remodelled islet company and vascularization and decreased hyperglycemia . Likewise, a seminal research remarked that the viability of isolated islet was improved, when cocultured with collagen blended hydrogel (collagen type I, collagen type III, and laminin) . It really is of remember that the coculture program is used not merely in improving healing efficiency of stem cells but additionally to contemplate the pathogenesis of diabetes. Within a conclusive research, a coculture program of BMSCs and macrophage helped to comprehend that association between regional inflammation and immune system response promotes diabetic periodontitis, especially by upregulating the appearance of chemokine (C-C theme) ligand 2 (CCL2) and TNF-in periodontal tissue . 10. Gene Editing in Stem Cell for Treatment of Diabetes and its own Complications Recent advancements in gene concentrating on, editing, and delivery possess managed to get feasible to build up a highly effective and long-term therapy for the treating hereditary disorders. Adult stem cells, such as HSCs and MSCs are considered as promising candidates for exploiting gene changes techniques in cell-based regenerative therapy [189C191]. Vectors derived from retroviruses and adenoviruses are most commonly used to transfer the genes in CHK1-IN-3 stem CHK1-IN-3 CHK1-IN-3 cells; however, the chances of random integration might be deleterious. The other limiting factor associated with gene editing is no retaining of the edited gene by stem cells during their ex vivo proliferation. To conquer the limitations of.

domain: biology


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Clinical Protocol and Data Management (CPDM) at Wake Forest Baptist Comprehensive Cancer Center (WFBCCC) provides support for the infrastructural elements of clinical research ? including finance, regulatory, data, and nursing management ? to promote WFBCCC science and its translation into the community, and promulgate National Cancer Institute and Cancer Center Support Grant objectives in clinical research operations. CPDM provides a broad range of management and quality control functions, including trial activation and monitoring, a centralized protocol document directory, a centralized database of protocol- specific data, data and safety monitoring activities that promote study participant safety, and assistance with complex regulatory issues. CPDM also provides high-quality services related to patient screening, obtaining informed consent, study enrollment, and safety reporting.
The Specific Aims of CPDM are 1) to centrally manage and facilitate cancer clinical trials that prioritize patient safety and optimize participation, especially among underserved populations at WFBCCC; 2) perform regulatory and data management, data and safety reporting, and quality assurance functions of clinical trials conducted at WFBCCC; 3) provide protocol coordination throughout the trial lifecycle for trials conducted at WFBCCC; and 4) provide investigational drug monitoring and storage for clinical trials at WFBCCC. Since the previous competing review, CPDM has been consolidated into a fully centralized model, under the leadership of Stefan Grant, M.D., J.D., M.B.A., as the Clinical Research Medical Director. As part of this consolidation, Disease-Oriented Teams now have a formalized role, including procedures for reviewing clinical trial protocols. The Disease-Oriented Teams include faculty members from all four Programs and serve as the platform whereby new transdisciplinary clinical trial concepts are initially presented, discussed, prioritized, and developed. Dedicated research nurses and data managers are assigned to support each Disease-Oriented Team. Review of serious adverse events continues to be conducted by the Safety and Toxicity Review Committee, while Phase III trials (including WFBCCC National Cancer Institute Community Oncology Research Program trials) are also monitored by a separate Data Safety and Monitoring Board. The Office of Cancer Health Equity continues to make strides towards eliminating barriers to underserved populations seeking care at WFBCCC and facilitating their participation in clinical trials. These efforts have included a catchment area needs assessment, institutional policy and process changes, faculty and staff support, development of underserved patient programs, and community outreach to underserved populations.
|Sirkisoon, Sherona R; Carpenter, Richard L; Rimkus, Tadas et al. (2018) Interaction between STAT3 and GLI1/tGLI1 oncogenic transcription factors promotes the aggressiveness of triple-negative breast cancers and HER2-enriched breast cancer. Oncogene 37:2502-2514|
|Goyal, Amrita; Carter, Joi B; Pashtan, Itai et al. (2018) Very low-dose versus standard dose radiation therapy for indolent primary cutaneous B-cell lymphomas: A retrospective study. J Am Acad Dermatol 78:408-410|
|Su, Weijun; Hong, Lixin; Xu, Xin et al. (2018) miR-30 disrupts senescence and promotes cancer by targeting both p16INK4A and DNA damage pathways. Oncogene 37:5618-5632|
|Miller Jr, David P; Denizard-Thompson, Nancy; Weaver, Kathryn E et al. (2018) Effect of a Digital Health Intervention on Receipt of Colorectal Cancer Screening in Vulnerable Patients: A Randomized Controlled Trial. Ann Intern Med 168:550-557|
|Bonin, Keith; Smelser, Amanda; Moreno, Naike Salvador et al. (2018) Structured illumination to spatially map chromatin motions. J Biomed Opt 23:1-8|
|Rimkus, Tadas K; Carpenter, Richard L; Sirkisoon, Sherona et al. (2018) Truncated Glioma-Associated Oncogene Homolog 1 (tGLI1) Mediates Mesenchymal Glioblastoma via Transcriptional Activation of CD44. Cancer Res 78:2589-2600|
|Maggiore, Ronald J; Callahan, Kathryn E; Tooze, Janet A et al. (2018) Geriatrics fellowship training and the role of geriatricians in older adult cancer care: A survey of geriatrics fellowship directors. Gerontol Geriatr Educ 39:170-182|
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Showing the most recent 10 out of 548 publications

domain: medical


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Bill Wagner is reporting on his blog that according to his sources, top Navy lacrosse assistant coach John Tillman is leaving Annapolis to take the head coaching job at Harvard. Tillman and Princeton assistant Dave Metzbower were rumored to be the two finalists to replace longtime coach Scott Anderson, who stepped down as head coach after 20 years to take a position within the athletic department. Metzbower allegedly took his name out of consideration this morning. Harvard is expected to make an official announcement later today.
Most Navy lacrosse fans figured this day would come eventually. Tillman is an excellent coach who devised some very productive offenses for Navy. He deserves this chance, and probably would have been hired away long ago if there were more head coaching opportunities in Division I. He leaves some awfully big shoes for Richie Meade to fill. I expected Navy’s offense to undergo a bit of a transition this year with the graduation of Ian Dingman. Now it’s almost guaranteed.


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Amritsar, July 6: Three women were found murdered at their house in Mukhowal village under the Ramdass police station here on Thursday. The police said they were strangled by some unknown persons though the police suspect the role of an insider.
The deceased were Kartar Kaur (80) of Makhowal, her daughter Harmeet Kaur (50) of Jhanjhia Kalan village and granddaughter Dilpreet Kaur of Chhichrewal village.
Neighbours said they were last seen on Tuesday. When the villagers did not see them for the last two days and foul smell started emanating from the house, they opened the house on Thursday and found them dead.
Senior police officials reached the spot and started investigations. A case of murder has been registered.
Parampal Singh, Senior Superintendent of Police, Amritsar rural, said Kartar Kaur had three sons — Gurdayal Singh, Kulwant Singh an Jaswinder Singh. While Gurdayal Singh was in Rishikesh, her other two sons had died. Jaswinder has two sons Amarbir Singh and Parneet Singh who also lived in the same village.
“The deceased had strangulation marks around their neck. There was no forced entry in the house,” said the SSP.
As per a preliminary probe, the police said Kartar had a land dispute with her grandsons Amarbir and Parneet though nothing concrete could be said about who killed the women. Forensic and technical teams were pressed into service.
Source Tribune India


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During the first conference, city officials discussed a plan to spend approximately $300,000 to pave city roads most in need of repair.
City Engineer Joe Matthews said paving will be paid for by the city’s gas tax funds, which by law can only be used for such infrastructure projects. Typic-ally, the city accumulates about $150,000 per year from these taxes.
Officials plan to combine the tax money from the current fiscal year and the upcoming fiscal year to pay for the paving and patching project.
“They’re going ahead and using the $150,000 they anticipate getting this coming (fiscal) year,” Matthews said.
Early next week city officials are expected to announce what roads will receive the upgrades.
For the most part, the funds are being split between the city’s five councilors and the mayor, so that the money will equally benefit Jasper’s five districts. Mayor Sonny Posey said Thursday he will divvy up his $50,000 share among the five districts, so that each district will get about $60,000 in road repairs.
However, Matthews said the split among the districts will not be completely equal since some districts have more roads and more need for repairs.
Matthews said the cost of paving will be $82.38 per ton of wearing surface material, which he said is a “good price.”
When the Council reconvened Thursday afternoon to discuss a proposed ordinance regarding the city’s leash law and suggested regulations for owners of dogs deemed as “vicious,” several citizens and city officials expressed concern about the matter.
Lisa Lockhart, a dog enthusiast who owns several pit bull terriers — dogs that are defined as “vicious dogs” in the proposed ordinance written by an ad hoc committee appointed by Posey — pointed out that under the proposal it would be illegal for her to take one of her pit bulls to the home of a friend who lives in Jasper.
The ordinance states that “a vicious dog shall only be allowed outside the property of the owner for emergencies, for necessary medical or health treatment or for transportation to a point (outside) the city limits of the City of Jasper.”
Officials also had a lengthy discussion about a provision that would only allow city households to have five dogs.
Councilor Gary Cowen pointed out that if a city resident’s dog has a litter of five puppies or more, they are not in compliance with the law.
“Then if (they) sell those puppies, I’ve double broken the law,” he added in regard to a proposal in the regulation aimed at banning residents from using their home to operated dog breeding facilities. During past discussions about the city’s dog laws, several residents alleged that a Jasper homeowner was using his property to breed and sell pit bull puppies.
City attorney Russ Robertson went over several provisions of the ordinance, including a requirement that dogs found unlawfully to be at large within the city limits of Jasper will not be released to owners unless they have received a rabies inoculation and have been spayed or neutered.
“There is a tremendous coincidence of not being spayed or neutered and attacking,” Robertson said. “If I read the statistics correctly, there is more coincidence of unspayed or un-neutered dogs attacking than any breed.”
Police Chief Connie Cooner Rowe said equal to the problem of dogs running loose in the city is where to put these animals when they are caught now that the Walker County Humane Society is no longer involved in housing dogs captured by Jasper Police Department officer John Tune.
“If we get into the business of collecting animals, stop there and tell me what I do with them,” she said. “I think we could fill every car up I’ve got with dogs every evening shift.”
Jasper Police Sgt. Tim Martin said he is looking into a United States Department of Agriculture grant for communities with fewer than 20,000 residents that “provides funding for essential community facilities” including private and public animal shelters.
“It could eliminate a lot of our problems,” he said.