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|Year : 2010 | Volume
| Issue : 2 | Page : 222-225
HIV/AIDS vaccine: An update
Population Council, 1230 York Avenue, New York City, NY-10065, USA
|Date of Submission||25-Apr-2009|
|Date of Acceptance||25-Mar-2010|
|Date of Web Publication||29-Jul-2010|
Population Council, 1230 York Avenue, New York City, NY-10065
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Nath A. HIV/AIDS vaccine: An update. Indian J Community Med 2010;35:222-5
| Introduction|| |
The global HIV/AIDS epidemic continues to take its toll of human lives. In 2007 there were 33 million people living with HIV/AIDS, with 2.7 million new HIV infections and two million HIV-related deaths.  With a total of 2.5 million people living with HIV/AIDS, India too is in the grip of the HIV/AIDS epidemic.  According to the HIV Sentinel Surveillance data 2004-2006, there are 156 Category A districts (where there is more than one per cent antenatal prevalence at any given time, in any of the sites, in the last three years).  Despite the recent progress in increasing access to treatment and prevention programs, the epidemic continues to outpace the global prevention efforts. In countries that are most heavily affected, the epidemic has led to a significant increase in household poverty and reduction in the life expectancy by more than 20 years. , The effects of gender inequality leave women and girls more at risk of exposure to HIV. In India, women are becoming increasingly vulnerable to HIV/AIDS and account for around one million cases.  Moreover, they have fewer and rather unfeasible options available to protect themselves such as abstinence and use of condom. The best hope of ending the epidemic lies in the development of a suitable vaccine.  Vaccines are one of the most effective public health interventions ever known. An HIV vaccine could either prevent disease onset or progression to AIDS. According to mathematical estimates by the International AIDS Vaccine Initiative (IAVI) - provided that other programs for treatment and prevention have been scaled up - an HIV vaccine with an efficacy as low as 30% and coverage as low as 20% could avert as many as 5.5 million new infections between the years 2015 and 2030.  The development of an effective vaccine has posed a wide range of challenges, as HIV has proven to be a uniquely complex virus.
| Types of HIV Vaccines|| |
Broadly speaking, the potential HIV vaccines may be classified as:
Live attenuated vaccines: Although scientists have studied live attenuated vaccines against HIV in animals, where they have shown high levels of protection, they are not currently being developed for use in humans because of safety concerns.
Subunit vaccines: Subunit vaccines contain a small protein or piece of the pathogen; the protein acts as a foreign antigen and elicits B cells of the immune system to produce antibodies against the antigen. The first AIDS vaccine developed and tested was designed using the subunit concept. The first AIDS vaccine to go through complete testing in humans, the AIDSVAX gp120 vaccine, was a subunit vaccine. This vaccine failed to protect against HIV infection in an efficacy trial, which is one of the reasons why scientists are working to discover better vaccine concepts.
DNA vaccines: This vaccine entails use of copies of single or multiple genes from the pathogen. The genes from the pathogen integrate with the human gene resulting in the formation of a protein, which is seen as a foreign or harmful antigen by the immune system and results in the production of an immune response. This is a common strategy being used for AIDS vaccine development, and many of the current AIDS vaccine candidates are DNA vaccines. DNA vaccines will not cause HIV infection, because the vaccines do not contain all the genes of the live pathogen.
Recombinant vector vaccines: This adopts the same strategy as DNA vaccines, except that the genes are carried by a harmless or a much weakened bacterium or virus, called a vector. Many of the current AIDS vaccine candidates are vector vaccines. Recombinant vector vaccines will not cause HIV infection because they contain copies of only one or several HIV genes, not all of them. Many scientists believe that the addition of a vector will allow the vaccine to be more effective in creating an immune response, rather than a DNA vaccine alone. Some of the candidate recombinant virus vectors include adeno and adeno-associated viruses, pox viruses such as Modified Vaccinia Ankara (MVA), and alphaviruses such as Venezuelan Equine Encephalitis (VEE) virus.
| Clinical Trial Phases for a Candidate Vaccine|| |
Broadly speaking, the clinical trial of a candidate vaccine is divided into three phases:
- Phase I: Phase I trials are conducted on small numbers (10-30) of healthy adult volunteers who are not at risk of HIV, to evaluate the safety and perhaps analyze the immune responses evoked by the vaccine, of different vaccine doses and immunization schedules. A Phase I trial usually takes 8-12 months to complete.
- Phase II: Phase II testing generates additional safety data as well as information for refining the dosage and immunization schedule. It involves a larger number of volunteers (50-500), which include a mixture of low-risk people and higher-risk individuals. These trials generally take 18-24 months to complete. The efficacy of the candidate vaccine may be tested in a version of this trial known as Phase IIb trial, also called 'test of concept trial' or step study. These trials enable the researchers to decide if the candidate is worth testing in larger Phase III trials. Hence, it helps to avoid unnecessary wastage of resources.
- Phase III: Phase III trials are conducted to assess vaccine efficacy. It involves thousands of volunteers from high-risk populations. The minimum duration of a Phase III trial could go up to a period of three years.
| Major Challenges Toward the Development of an Effective HIV/AIDS Vaccine|| |
Although it has been decades since the onset of the HIV epidemic, the wait is still on for the discovery of an effective vaccine.
a) Scientific challenges: The nature of the HIV virus has created a number of obstacles in the way of development of a potent HIV/AIDS vaccine. These include:
- Genetic diversity: Once the HIV virus enters the CD4 cell, it multiplies at a very rapid pace resulting in the production of copies that are genetically diverse from the parent virus. This makes development of an effective AIDS vaccine much more difficult because it will have to protect against so many different virus strains.
- Formation of neutralizing antibodies: None of the vaccine candidates have been effective in inducing the formation of neutralizing antibody against the globally diverse and circulating strains of HIV. Most licensed vaccines against other diseases are thought to work because they induce virus-specific neutralizing antibodies.  Moreover, there is lack of information on the immunological correlates of protection against HIV/AIDS.
- Lack of a proper animal model for pre-clinical testing: Prior to testing in humans, vaccine candidates are developed and tested extensively in the laboratory and then in different animal models. In relation to the development of the HIV vaccine, the vaccine candidate is administered to macaques that are later infected with simian immunodeficiency virus (SIV), because HIV does not infect any other animal.  As a result, the animal model for testing the vaccine is not proper as it cannot mimic the actual HIV infection, as in humans.
b) Programmatic challenges: ,,
- HIV vaccine clinical trials are difficult, long, and expensive.
- Insufficient funding allocated to vaccine development.
- Recruiting volunteers may be difficult in developing countries because of less education, myths, and misconceptions about the vaccine.
- Lack of political commitment.
- Slow approval processes in developing countries.
| Ongoing Global Clinical Trials|| |
A number of institutions are involved in HIV vaccine development, especially the US National Institutes of Health, the US Military HIV Research Program, the US Centers for Disease Control and Prevention, the French National Agency for Research on AIDS, the European Community, the International AIDS Vaccine Initiative, WHO, UNAIDS, and others, including the vaccine industry. The first phase I trial of an HIV candidate vaccine was conducted in USA in 1987, using a gp160 candidate vaccine. At present there are 24 candidate vaccines in various stages of development.  Out of these, 18 are undergoing the Phase I trial, three are in Phase I/II trials, two are in the Phase II trial, and only one is in the Phase III trial; which is VaxGen's gp120-based AIDSVAX, which is being tested in Thailand. The trials are ongoing in many countries in the developing world, including Botswana, Haiti, Kenya, Peru, South Africa, and Uganda. [Table 1] shows the types of HIV/AIDS vaccine in different stages of development.
| Clinical Trials in India|| |
In India, leading institutions including the Indian Council of Medical Research (ICMR), the National AIDS Control Organization (NACO), and their partner International AIDS Vaccine Initiative (IAVI), and institutions under the Department of Biotechnology (DBT) have been intensively involved in the area of AIDS vaccine development. The Indian HIV vaccine development program has always been focusing on the development of vaccines designed to prevent HIV subtype C.  The first ever conducted Phase I trial in India was that of an adeno-associated virus (AAV)-based vaccine (tgAAC09) expressing gag, protease, delta-RT HIV-1 subtype C genes, administered intramuscularly to 30 healthy, HIV-uninfected male and female adult volunteers. It was initiated in February 2005, at the National AIDS Research Institute (NARI), Pune, as part of a joint trial with centers in Germany and Belgium, and was completed successfully in December 2006. It was observed that the vaccine was generally safe, well-tolerated, and modestly immunogenic. , Another Phase I trial had been initiated in Chennai, in January 2006, to assess the safety and Immunogenicity of Modified Vaccinia Ankara (MVA)-based vaccine (TBC-M4), an attenuated form of the vaccinia virus expressing env, gag, tat-rev, and nef-RT HIV-1 subtype C genes.  Preliminary results of this trial have suggested safety, tolerability, and 100% immunogenicity.
| Conclusion|| |
There is an urgent need for a safe, effective, affordable, and feasible HIV/AIDS vaccine, to counter the rapidly progressing epidemic. An HIV vaccine with an efficacy threshold of as low as 30% efficacy has been suggested to be acceptable and likely to be taken up by paying individuals in the private market.  Conducting AIDS vaccine trials, especially in countries like India requires cooperation and coordination from different segments of society, which include political leaders, program managers, policy makers, scientific communities, non-governmental organizations, community leaders, and HIV-affected populations. Critical ethical issues would need to be handled when conducting these trials, including the level of care and treatment that should be offered to the volunteers, who may become infected during the course of the trial.  Involvement of public health specialists in vaccine development is of paramount importance, so that research findings are rapidly transformed into effective and acceptable programs.
| References|| |
|1.||Status of global HIV epidemic. Report on the global AIDS epidemic. Joint United Nations Programme on HIV/AIDS. Geneva: UNAIDS; 2008. p. 30. |
|2.||National Family Health Survey (NFHS-3) India: International Institute for Population Sciences (IIPS) and Macro International. Mumbai: IIPS; 2007. |
|3.||NACO, MoHFW. HIV sentinel surveillance and HIV estimation in India 2007: A technical brief. Government of India; 2008. |
|4.||Commission on AIDS in Asia. Redefining AIDS in Asia - crafting an effective response. Oxford University Press, New Delhi.2008. |
|5.||UNDP. Human development report. New York: UNDP; 2005. |
|6.||National AIDS Control Organization. New Delhi: NACO; c2007 [Available from:
http://www.nacoonline.org/Quick_Links/Women/ . [cited in 2009]. |
|7.||Esparza J, Bhamarapravati N. Accelerating the development and future availability of HIV-1 vaccines: Why, when, where, and how? Lancet 2000;355:2061-6. |
|8.||IAVI. Estimating the global impact of an AIDS vaccine - IAVI policy brief. Available from:
http://www.iavi.org/viewfile.cfm?fid=35239 . [cited in 2006]. |
|9.||Types of HIV vaccines. Available from:
http://www.iavi.org/viewpage.cfm?aid=1689 [last accessed on 2009 Feb 10]. |
|10.||Vaccine science. Available from:
http://www.iavi.org/viewpage.cfm?aid=27 . [accessed on 2009 Feb 3]. |
|11.||Understanding the challenges of vaccine development. VAX primer. Available from:
http://www.iavireport.org/vax/primers/vaxprimer34.asp . [cited in 2007]. |
|12.||Understanding neutralizing antibodies. VAX primer. Available on:
http://www.iavireport.org/vax/primers/vaxprimer32.asp . [cited in 2007]. |
|13.||Esparza J. An HIV vaccine: How and when? Bull World Health Organ 2001;79:1133-7. |
|14.||Understanding AIDS Vaccine Pre-clinical development. Available on:
http://www.iavireport.org/vax/primers/vaxprimer29.asp . [cited in 2006]. |
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|16.||Excler JL, Beyrer C. Human immunodeficiency virus vaccine development in developing countries: Are efficacy trials feasible? J Hum Virol 2000;3:193-214. |
|17.||Esparza J, Burke D. Epidemiological considerations in planning HIV preventive vaccine trials. AIDS 2001;15:49-57. |
|18.||Ongoing trials of preventive AIDS vaccines. Available from:
http://www.iavireport.org/specials/OngoingTrialsofPreventiveHIVVaccines.pdf. [accessed on 2009 Feb 10]. |
|19.||Sahni AK, Prasad VV, Seth P. Genomic diversity of human immunodeficiency virus type-1 in India. Int J STD AIDS 2002;13:115-8. |
|20.||Mehendale S, van Lunzen J, Clumeck N, Rockstroh J, Vets E, Johnson PR, et al. A phase 1 study to evaluate the safety and immunogenicity of a recombinant HIV type 1 subtype C adeno-associated virus vaccine. AIDS Res Hum Retroviruses 2008;24:873-80. |
|21.||Van Lunzen J, Mehendale S, Clumeck N, Vets E, Rockstroh J, Anklesaria P, et al. A phase I Study to evaluate the safety and immunogenicity of a recombinant adeno-associated virus HIV vaccine. 14th Conference on Retroviruses and Opportunistic Infections; 2007. p. 25-8. |
|22.||Excler JL, Kochhar S. Preparing for AIDS vaccine trials in India: An update. Sankalp 2004;3:1-3. |
|23.||Ramanathan VD, Kumar M, Mahalingam J, Narayanan PR, Solomon S, Boaz M, et al. A Phase 1 study to evaluate the safety and immunogenicity of a recombinant modified vaccinia ankara virus (TBC-M4) multigenic HIV subtype C Vaccine. AIDS Vaccine 2007;24:20-3. |
|24.||Forecasting demand for preventive HIV vaccines in India. Policy research working. Available from:
http://www.iavi.org/viewfile.cfm?fid=45306. [accessed on 2009 Feb 3]. |
|25.||Guenter D, Esparza J, Macklin R. Ethical considerations in international HIV vaccine trials: Summary of a consultative process conducted by the Joint United Nations Programme on HIV/AIDS (UNAIDS). J Med Ethics 2000;26:37-43. |
|26.||Ongoing clinical trials. Available from:
http://www.iavireport.org/trials-db/Pages/TrialResults.aspx?TDBQuery=87cb29d8-8e2e-4c27-89fc-9806a2a74fd5 . [accessed on 2009 Nov 21]. |


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What are some of your all-time favorite video lectures-… We're hard at work trying to keep our community clean, ... Video Game Wallpapers > Other > Dead Reckoning 3 - The Crescent Case02 Dead Reckoning 3 - The Crescent Case02. Jessie’s Game (Book 2): Dead Reckoning is a 127,000 word novel from the world of GAMELAND. Ghost Ship Cube Tower for Dead Reckoning. There are no witnesses, and everyone at the carnival denies knowing the victim. For ages 16 and older. Dead Reckoning #3 But I don’t wanna be a Pirate!! The Tome II update, "Reckoning", is available now for the asymmetrical multiplayer horror game. Loosely inspired by the 2013 Boston Marathon bombing, Dead Reckoning stars KJ Apa and Scott Adkins as brothers with very different views of American culture. Top New Video Games Releasing On Switch, PS4, Xbox One, And PC This Week -- September 6-12, 2020 There's lots of new stuff in Kingdoms of Amalur: Re-Reckoning… Games and quizzes for The Walking Dead. Dead Reckoning, a film by John Cromwell; Dead Reckoning, a film by Robert Michael Lewis; Dead Reckoning, a film by Andrzej Bartkowiak; Land of the Dead or Dead Reckoning, a 2005 film . Posts about video game written by Noah Lloyd. Uploaded: Monday, March 19, 2012 At least once per game someone quotes the Seinfeld puffy shirt episode. Hidden object detective adventure games from Eipix Entertainment. The comic book style video game has only been available on AMC’s website site as of late but now a new app for Android devices allows you to play it whenever and wherever you need your ‘Dead’ fix. Download Walking Dead: The Game and enjoy it on your iPhone, iPad, and iPod touch. Anecdote: The original reason I, personally, never finished my run of Kingdoms of Amalur back in 2012 was due to the fact that multiple annoying glitches were encountered in a single playthrough with a game-breaking bug necessitating the game being shelved. It would be easy to describe Dead Reckoning as “a Pirate Game”. The only thing better than solving a new Dead Reckoning whodunit game, is a Dead Reckoning whodunit game at the carnival! The Walking Dead
Ultimate Fan Games. The ship was a free item in the KS Campaign for Legendary & All-In Backers. This isn’t the game that will keep the PSP in your hands for a extended period of This, we suspect, is not intentional. Dead Reckoning, the name of the firework launching vehicle from the film Land of the Dead "Dead Reckoning", an episode of the television series The Professionals He is seen working closely with Shane, as well as the other known deputy, Don. The oldest, largest and most accurate video game database covering over 280 platforms from 1950 to date! May 2018 Update: Chapters 1 to 6 available on Android and Amazon Fire. 4:1–4:6, Newport, RI, USA, May 2006. Kingdoms of Amalur: Reckoning 'The Legend of Dead Kel' DLC Trailer Amalur's 'The Legend of Dead Kel' DLC gets announced and you now get chance to see it in action. Tanpepper’s GAMELAND. RT @Silent0siris: Alright game design friends- here's a tricky one for you. Upgraded Cargo for Dead Reckoning. Hi everyone! Originally referred to as “dead reckoning,” markerless AR uses a combination of camera systems, dedicated sensors, and algorithms to accurately detect and map the real-world environment—such as the locations of walls and points of intersection. Dead to Rights: Reckoning is a standard action game that attempts to follow in the footsteps of the console game Dead to Rights II, by offering nothing more than straightforward action. Dead to Rights: Reckoning, however, challenges both of the above notions. Enter your email address to follow this blog and receive notifications of new posts by email. Jan 17 2019. W. Palant, C. Griwodz, and P. Halvorsen, “Evaluating dead reckoning variations with a multi-player game simulator,” in Proceedings of the 16th Annual International Workshop on Network and Operating Systems Support for Digital Audio and Video (NOSSDAV '06), pp. For PC, Mac, iPad, iPhone, Android and Amazon Fire. The highly-rated epic cyberpunk series was first released in monthly episodes between May and December 2012. With Collector’s Editions (CE) – which include extra game play and bonus content! He is a deputy of the King County Sheriff's Department in King County, Georgia. Things they don't teach you at architecture school - if you want to design environments for video games. With Laila Berzins, Erik Braa, Bill Corkery, Dan Lawson. The highly successful show The Walking Dead is looking to wrap up its second season, and one thing that has been keeping people busy in between episodes is AMC’s ‘Dead Reckoning’. (… T.co. Two sequels, Wayward and Redeemer, followed in 2003. Dead to Rights Reckoning isn't an awful game, but it's jut got nothing about it that warrants much attention. Hunter: The Reckoning is a 2002 hack-and-slash video game developed by High Voltage Software and published by Interplay Entertainment for the Xbox and GameCube.It is based on the tabletop role-playing game of the same name, and is part of the larger World of Darkness series. Pick your ship and wingmen and get ready to do battle against alien races in cylinder shaped battlefields. x AMC - Latest full episodes and extras AMC Network Entertainment LLC VIEW. Images (41) "Dead Reckoning" is the 13th episode of season 2, and the 36th produced hour of Person of Interest.
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This post is part of the 12 Days series.
I was one of the many Gundam fans who were fully hyped for the Gundam Unicorn anime, since its announcement. As I hoped, the anime turned out to be a 6-episode OVA, which solves most of the misgivings I had.
Late February of 2010, I watched the first episode of Gundam Unicorn as it came out. It was a classic Gundam opener, where a boy’s peaceful civilian life is upheaved by the shadow of war, and becomes a pilot by circumstance.
And it happens again.
But what is different? The Gundam is not stolen or hijacked. Its proprietor, Cardeas Vist, entrusts it to Banagher Links, his own son. Falling into a Gundam cockpit is a staple in the real robot genre, but has been routinely abused by many–so much that it has become a banal, can’t-we-just-get-over-with-it event.
To hell with that, Gundam Unicorn says. Unlike many others before him, Banagher makes an explicit choice, desiring the Unicorn, in order to be desired by Audrey. And in the same event, he reconciles with his estranged father. Most fatherhoods in Gundam–this one included–are cheerless, but few are actually resolved in a good way. I suppose it’s a little thing that speaks volumes.
So was this scene banal? No.
Something we could skip to see the Gundam blow up stuff faster? Hell no.
And the payoff, with the music that accompanies, is magnificent.
Many criticize Gundam Unicorn for being a slave to well-worn genre tropes, but this just makes them blind to the little details. It may not be new, but it’s done well. Sometimes that’s what matters. And in response to that, this is my definitive moment of 2010.
It starts once more, where everything first began.


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Aerys is a non-blocking HTTP/1.1 and HTTP/2 application, WebSocket and static file server written in PHP based on Amp.
This repository is deprecated in favor of
It still exists to keep the documentation and also Packagist working as before.
composer require amphp/aerys
Running a Server
php bin/aerys -c demo.php
Simply execute the
aerys binary (with PHP 7) to start a server listening on
the default configuration file (packaged with the repository).
-d switch to see some debug output like the routes called etc.:
php bin/aerys -d -c demo.php
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php bin/aerys -c /path/to/my/config.php
-h, --help switches for more instructions.
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text: After Warner is arrested for a series of crimes he has no recollection of committing, he breaks out of prison, returns home to grab his daughter and girlfriend, and then goes on the run from the wall. Before too long, he winds up in the mysterious Colorado town of Pinevale. In Pinevale, a new hell begins to be unleashed when a strange cult starts to wreak havoc on his family. Weeping Of The Caverns is the first of several novels by William Becker. The novel was first published in late 2015 before a second edition was published shortly after. Within a few years, an Ebook edition was released with an exclusive cover. WARNING: EXPLICIT CONTENT.

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text:
When I am Gone
Life is short and sometimes strange,
I can't explain it, but I know it is true.
If only I had met you when,
I would have loved to spend my life with you.
I think you will miss me when I am gone!
You are like a flower covered in the early morning due.
Each petal glistening with beauty and majesty.
The sun reflecting off of your moist radiant face,
You are the most beautiful flower in the garden it is true,
I am pretty sure that you will miss me when I am gone.
I admire your beauty and want to touch,
I need to know your touch and embrace.
I want to pick you, love you, touch you, smell.
I can't wait to have you as my own.
Most likely, you will miss me when I am gone.
Make no regrets, give into love and kiss me, live life,
If only time had been more kind, I would ask you to be my wife.
Who could ever love you more than I alone,
Who could ever hold you closer than Me,
I know that you will miss me when I am gone.
Make sweet love to me and hold me with all your might.
Let me sleep with you, stroke you and hold you tight.
Let me whisper in your ears, kiss your neck and touch your breast.
I would make you feel my love.. mine alone!
Oh my, I am going to miss you when I am gone!

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On at about 20:22:48 PM, Moelogo - Mumidani was updated.
Mp3 Download » Moelogo - Mumidani; Moelogo, the front act of Motrakz Records and a London-based Nigerian singer, releases another project, 'Myself EP,' to close out the year 2020.
Mumidani by Moelogo—is the first track on the 6-track EP, which was produced by PriimeBeats.
Moelogo, a talented Nigerian singer, returns with another hit titled Mumidani, as one of his 2020 songs, which is currently trending in Nigeria and the United Kingdom. Moelogo's Mumidani is the first track on his highly anticipated outstanding Extended Play (EP). EP is my name.
Moelogo kicks off the new year by releasing the visualizer for his song "Mumidani," which is taken from his 2020 project "Myself EP."
Is it safe to say that Moelogo's next EP will be titled "I" if you're like me and notice patterns? As in... "I, Myself, and I"?
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80 to 100: Rossman makes lasting impression on city
Paul Rossman treasures the relationships he’s developed in Enumclaw, his home of more than 60 years.
Now creeping up on his 92nd birthday, the former farm boy, Navy veteran and electrician can put a lifetime in perspective. “I have a lot of friends in Enumclaw,” he says. “I guess that’s why I never left.
”From his cozy digs at High Point Village, Rossman relates stories that make one thing absolutely clear: just as the town has been good to him, Rossman has made an indelible mark on the community.
If nothing else, there were the decades he owned and operated Rossman Electric. The small company experienced its ups and downs, but he rustled up enough business to keep four vans rolling; and the firm’s payroll meant a small corps of workers kept food on the family table.
Behind the scenes, he helped put food in the mouths of those who perhaps couldn’t afford a decent meal.
Rossman was a key player in the early days of the community food bank, back when it was housed at Kibler Elementary and before it was taken over by the Kiwanis Club. His involvement began when then-mayor Fred Farman asked Rossman to provide some electrical work; Farman admitted there was no money immediately available, so Rossman waited patiently for a check that finally came. He was also known to loan one of his vans when a load of food had to be picked up.
Rossman’s community involvement stretches in different directions. He has been a regular through the years, walking in community parades, hoisting the flag for the Veterans of Foreign Wars. He’s also a lifetime member of both Kiwanis and the Enumclaw Historical Society and belongs to Knights of Columbus, an affiliation through Sacred Heart Catholic Church, where he attends every Sunday.
Rossman admits, somewhat modestly, that his legacy will live on long after he’s gone.
Operating a small business wasn’t always easy and Rossman took opportunities – in the form of real estate purchases – to supplement his income. If business was slow, he said, there was always money coming in from rental properties he owned with his wife, who died in 1997.
Some of those are still bringing a steady income and have been placed in a trust. He and his wife identified five local charities and, after his passing, those charities will be the beneficiary of Rossman’s holdings.“All that comes out of that trust will stay right here in Enumclaw,” he says proudly.
Rossman wasn’t always in a position to help others – in fact, quite the opposite.He was born Oct. 20, 1919, on a South Dakota farm, near the town of Stickney. It was a small community then and remains so, currently boasting a population of less than 300.
“Times were tough back then,” he says, recalling that his father worked hard to collect wages of 37 cents per hour. Seeking a better life for his family, Rossman’s dad borrowed $100 and jumped at the opportunity to move to Bremerton, Wash., and take a job in the naval yard. It was early 1941 and Rossman, a young man at the time, made the move west, shortly before the world changed.
The attack on Pearl Harbor came just months later and young men everywhere, including Rossman, lined up to join America’s fighting forces. He had suffered a nasty broken leg when he was 16 and there was some thought that it might disqualify him from serving. He recalls telling his father, “I hope they take me, because I don’t want to stay home.
”The military wasn’t too selective at that time and Rossman soon found himself in the Navy. He had learned electrical work in South Dakota and served as an electrician’s mate.
From a large family of seven boys and two girls, Rossman notes that at one time, during the war, there were five Rossman brothers in active duty. One was a Pearl Harbor survivor and all made it home.
His father’s connections had brought the family to Enumclaw, but the kids struck out on their own.
Following the war, “we all kind of scattered out,” he said.
Rossman stayed, though, having landed a job with a local electrician. By 1951, he had founded his own company.
“I did everything,” he said, citing memorable jobs like wiring one of the ski lifts at Crystal Mountain and helping with the renovation of the long-abandoned Lester school. The school had been heated with coal but was being switched to electric heat.“I liked to go out to those places to see the wildlife,” Rossman said.
For all his business accomplishments and community involvement, Rossman is quick to point out nothing compares to family. He and his wife raised three children: a daughter remained in Enumclaw, their son is in South Prairie and another daughter isn’t too far away, residing in Redmond.
Rossman moved into quarters at High Point Village after a health scare nearly a year ago.Working to help others, he was delivering food from Sacred Heart to the food bank at More Pennies From Heaven. Rounding a corner, Rossman slipped on some ice and fell, breaking his hip. Things took a turn for the worse and he spent four days in a coma.
“I came out of it good,” he said, adding that doctors credited his active life with a speedy recovery.He has slowed down some, but there are still friends to visit, VFW meetings to attend and church services on Sunday. In all, he says, “I’ve had a good life.”

domain: news


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If you're looking for the ultimate Beatles collector's item, look no further than Beatles Box of Vision, a lavish storage case for not only the remastered CDs, but other releases such as the Anthology volumes, Love, Let It Be…Naked, and more. Ultimately the package provides the user with a powerful connection between two kinds of art: their music and their visual impact.
The cloth case holds a treasure trove of Beatles album artwork—an LP-sized book reproducing all the cover art, sleeve, and gatefold art for the UK and American releases; a Catalography guide to the Beatles' entire catalog; and vinyl sleeves in which to store CDs.
Each sleeve is emblazoned with a black and white reproduction of each album cover, enabling the user to easily store the CDs in chronological order. CD booklets may be stored right in the same sleeve as the discs. Both are held in separate sleeves, so the CD can be removed without disturbing the booklet.
Collectors will find the Catalography a particularly useful resource, as it displays the UK and American releases side-by-side. Essays explaining the differences in cover art and music content accompany each album. The tome also features an essay by Bruce Spizer, author of such essential reference books as The Beatles' Story on Capitol Records and The Beatles Are Coming: The Birth of Beatlemania in America.
The cloth-bound album artwork book displays, in beautiful full-color resolution, all cover artwork, back covers, and gatefolds from each Beatles release. Readers can view each cover in exquisite, close-up detail. Like the Catalography, the book includes the UK and American releases as well as special releases like Love and Let It Be…Naked.
As a final touch, the back of the cloth box is emblazoned with the last line from Abbey Road's “The End”: “And in the end/The love you take/Is equal to the love/You make.”
Jonathan Polk, creator of the Beatles Box of Vision, first conceived this ultimate tribute to The Beatles over nine years ago. The main catalyst was his continued frustration with CD storage issues and album artwork shrunk down to CD booklet size. “I wanted to address all the things that frustrated me about CDs, and what I felt was disconnecting fans, especially young fans, from artists and albums: the abandonment of large size album artwork, and the difficulty of organizing and displaying CD collections in a satisfying way,” Polk states.
After imagining the product, Polk encountered another obstacle: locating quality images of the album artwork, particularly more obscure photographs. “The actual Beatles package took close to two years to get together,” he explains. “The artwork comes from a combination of Apple Corps archives, EMI's archives, collectors and Ebay.” Eventually he hired a team of restoration experts who “color corrected, cleaned up and created the gorgeous prints. I learned a lot, and we spent many hours on very small details, but I had a great team to help me…with such beautiful art, I was not going to start skimping on the final product.”
The ultimate goal of the package, Polk states, is to reconnect fans with The Beatles' vast catalog. In addition, he wants to appeal to younger and older fans alike, “to give new young fans the context to appreciate the career and chronology of the Beatles, and on a much deeper level, so that it at least approximates how we got to appreciate it,” he says. “And of course, to give long time fans a context to re-connect with the artwork and their memories, especially when they pull out the remasters.”
Thus far, the Beatles Box of Vision has received positive reaction from fans. “I love hearing from fathers who sat down with their kids to listen together and look at the album covers and talk about what the music meant to them when they were kids,” he explains. “I get emails every day from people who are over the moon excited and in love with it. As long as they appreciate it—whether it is because of re-connecting with their memories, discovering new things, or getting to share it with their kids—I'm all good.”
The Beatles: Box of Vision retails for $89.99 (plus shipping) and can be ordered through the Box of Vision website. Descriptions of the box's contents as well as a virtual tour are also available on the site.Powered by Sidelines


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A systemically important financial institution designation for the three largest U.S. insurers — MetLife Inc., Prudential Financial Inc., and American International Group Inc. — may put them at a disadvantage to their competitors. Click here to continue reading.
Foreign institutional investors bought $179 million of equities across India, Indonesia, South Korea, the Philippines, Taiwan, Thailand and Vietnam in the week to Wednesday, compared with net sales of about $440 million the week prior. Click here to continue reading.
Bloomberg Municipal Market Q1 StatBook from Bloomberg Briefs Take a trial to our market leading Municipal Market newsletter - click here.
By Sabrina Willmer Mount Kellett Capital Management, founded by two former Goldman Sachs Group Inc. executives, plans to raise a new fund matching the $4 billion gathered in 2012 for its last global special situations vehicle, according to two people familiar with the situation. Mount Kellett Capital Partners Fund III, which is targeting a first [...]
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by Andrew Berens, MD, Senior Healthcare Analyst and Grace Guo, Bloomberg Industries Avanir’s Nuedexta may receive a decision from the Committee for Medicinal Products for Human Use (CHMP) this week as a treatment for pseudobulbar affect (PBA). Approval in the EU would be the second regulatory nod for the drug. PBA is also called emotional [...]
While the U.S. has delayed final Basel III implementation, most of the largest publicly traded banks are in early compliance based on their pro-forma estimates. Click here to continue reading.
Page 1 of Structured Notes this week: Gold’s decline of about 14 percent in two days put more than a billion dollars of U.S. structured notes at risk. Inside the full edition: Rabobank makes deep cuts in its equity derivatives team amid tighter regulations, sales of notes in the Brazilian real tied to government debt [...]


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What is a board game?
What is a board game? Board games, also known as tabletop games, are games in which players use game pieces to move around a game board. Most people play board games at home, but there are other places that allow people to play board games, like casinos and bars. Some popular board games are Monopoly, Clue, and Scrabble. Board games have been popular for hundreds of years. The ancient Egyptians were among the first people to play board games. The ancient Egyptians played several different types of boardgames, including games like Senet and Senet. The ancient Romans were also known to play board games. One popular Roman board game was called Ludus. The Romans were known for playing board games that were similar to today's board games. The Roman board game Ludus was very similar to modern board games.
What is the best board game for children?
What is the best board game for children? The best board games for children include games that have colorful pieces, are easy to play, and have a fast-paced challenge. Games like Monopoly and Scrabble are good board games for children because they feature colorful pieces that are easy for younger children to handle. Children also love board games that feature fast-paced challenges because they can get very competitive when playing games. Children can also learn valuable skills while playing board games, like learning how to plan ahead and using strategy.
Why are they called board games?
Why do they call board games board games? Board games are also known as tabletop games. This is because board games are played on a surface that can be considered a tabletop. Most board games are placed on tables, which is probably why they're also called tabletop games.
What are some classic board games?
What are some classic board games? Chess is a popular board game that people all over the world enjoy. Chess is a board game in which players use game pieces to try and move their pieces around the game board. The most famous chess game is chess. Other popular chess games include shogi and xiangqi.
What are some new board games?
What are some new board games? Some popular board games are modern board games that feature updated rules and gameplay. One of the most popular modern board games is chess. Chess is a board game in which players use game pieces to try and move their pieces around the game board. One of the most popular modern board games is chess. Chess is a board game in which players use game pieces to try and move their pieces around the game board. The rules of chess are slightly different than the chess rules of the past, but the game of chess is still the same classic game that so many people all over the world enjoy.
What are some board games?
What are some board games? Board games are great for having fun and for spending time with your family. They have many different uses, including helping you to escape the real world, helping you get exercise, and helping you practice your social skills. Board games are a lot of fun and it's easy to play them with other people. However, many people aren't aware of the many different types of board games that are available. There are many different types of board games, including board games that require you to build something, board games that require you to move pieces around, and board games that require you to roll dice. Board games can be played in different ways, including by one person and by multiple people at the same time.
What are they used for?
What are they used for? Board games use many different skills, including problem solving, critical thinking, creative thinking, and strategy. Many people use board games as a way to practice important skills they can use in the workplace. This is especially important for people in careers where they use computers on a daily basis. These careers include programming, engineering, and software development. Another reason why board games are important is because they can be a great way to relieve stress. Board games can help you relax and forget about your problems for a while.
What is the best board game for the Christmas season?
What board game is ideal for the holiday season? Playing board games is popular throughout the winter and around Christmas. Many board games have winter themes, which adds to their enjoyable mood. Because they both require moving across the board to gather various objects, board games like Clue and Monopoly are ideal for the holiday season. Playing board games like Betrayal at House on the Hill and Pandemic is enjoyable since both of them feature intense fighting. Because they both entail constructing various structures, board games like Carcassonne and Settlers of Catan are ideal for the Christmas season. Board games with lots of fast-paced action, like Munchkin and Forbidden Island, are enjoyable. Because they both entail traveling between different locations, board games like X-Wing and Ticket to Ride are enjoyable to play. Risk and board games like Ticket to Ride are enjoyable because they both simulate a conflict between opposing parties. Trading is a pleasant aspect of board games like Settlers of Catan and Puerto Rico, which makes them enjoyable. Board games with warfare, like Risk and Pandemic, are enjoyable because of this. Because they both entail conflict, board games like Carcassonne and Pandemic are enjoyable.
What are some of the best board game themes?
What kinds of board games are there? The cooperative game and the competitive game are the two main subcategories of board games. In cooperative games, players collaborate. In order to acquire various objects and achieve various objectives, players must cooperate in these games. Dominion, Carcassonne, and Sushi Go are a few examples of cooperative games. Players compete against one another in competitive games. Players compete against one another in these games to gather various things and accomplish various objectives. Monopoly, Risk, and Clue are a few examples of competitive games.
What are some classic board games?
What traditional board games are there? People all throughout the world love playing the board game chess. Players attempt to move their pieces across the playing board in the board game of chess. Chess is the most well-known chess game. The chess variations shogi and xiangqi are also quite well-liked. Modern board games with new rules and gameplay are some of the most well-known board games today. Chess is one of the most well-liked board games today. Players attempt to move their pieces across the playing board in the board game of chess. The game of chess is still the same traditional game that so many people enjoy across the world, even if the rules have changed slightly from those of the past.


text: There's a lot of Federline Hentai Videos to choose from, even if I just stick to the fuck-fest games using evaluations. My options include Dressup, Action, Adventure, Puzzle, Maximum Rated, along with Cartoon. If you're a gamer, consider about investing. This is peculiarly applicable to those who permanently play games, as you will want to get the most out of your graphics to maximize your gameplay. Get prepared to switch how that you examine Federline Hentai Videos for ever. In the event that you thought you'd seen Federline Hentai Videos earlier, it's nothing in comparison to everything you may obtain here, at the 1 Federline Hentai Videos site for admirers. What we suggest here is nothing but the best Federline Hentai Videos in the world, created and made from Japan by masters of their art. While there are many other Federline Hentai Videos sites out there that claim to suggest a broad diversity of Federline Hentai Videos, they're nothing compared to what you can find here. We simply take Federline Hentai Videos very gravely -- it's what we do! No other site offers these many Federline Hentai Videos that you can play online right. If you like playing with excellent Federline Hentai Videos, then you definitely found the ideal location. Prepare for the porno gaming practice.

domain: hobby


For a long time, the Arizona Coyotes were seen as one of the bad franchises in the NHL. They still have a lot of issues when it comes to running an organization but hockey is on the come-up there.
Since the season started, they have been right there near the Wild Card line in the Western Conference. They have as good of a chance as anybody to be one of the teams that get in.
On Wednesday night, they were put to the test by the Colorado Avalanche who have been one of the best teams in the league for a long time now. With studs like Nathan MacKinnon, Mikko Rantanen, and Cale Makar there, they are hard to beat.
It gets even harder to beat them when they get out to a 4-0 lead. Lawson Crouse's 15th goal of the season scored in the later stages of the second period gave the Yotes some life.
The Arizona Coyotes are never out of a hockey game in 2023-24.
Michael Kesselring, Jason Zucker, and Sean Durzi all scored third-period goals to tie the game. Durzi's goal came at 17:53 and the fans at Mullett Arena went crazy.
The comeback was complete when Jack McBain scored the overtime winner at 4:40. Instead of getting to the shootout, they were able to get the win it with 20 seconds to spare.
Following the win, the Arizona Coyotes are 18-14-2. That is good for 38 points which is the first Wild Card position in the Western Conference. They are one point clear of the St. Louis Blues who are the first team below the line.
They also trail the Dallas Stars by six points for the third spot in the Central Division. There is a lot of work to be done to make the playoffs but they just might have what it takes to get it done.
Mullet Arena is a great place for the Yotes right now. It isn't their long-term home but the barn is always rocking when they play. The fact that they are good makes it even better. Don't be surprised if they are a playoff team. They look like one at this time.


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Listening to Samuel Jack is soothing whether he is singing about love or loss. Let it All Out is the more joyful of songs on his latest EP; a real get up and go melody with reflections of gospel and soul. He says it’s a “happy go lucky song” about “togetherness” and saying “it’s ok to make mistakes, be happy.” The video reflects this and is lighthearted and positive, a day spent with his mates in beautiful English countryside steeped in sunshine and lots of colourful balloons. Samuel seems like a relaxed and carefree man so it’s somewhat surprising to hear so much pain and emotion in some of his music. You can just picture him in his caravan in Dorset surrounded by nature and tranquility, writing about his life.
He doesn’t want you to know he is sensitive, but no one could write the kind of music and lyrics he does if they didn’t have a heart and feelings. Of course, I have to mention at this point that he is “rugged and manly,” but no one minds sensitive anyway, do they? And the overall theme of the EP is love, loss, and happiness. Samuel says he writes about personal experiences; “the EP was born through a period in (his) life that wasn’t the most easy“. He is “deeply attached” to all of his songs, they are “pretty heartfelt.” It is a fantastic EP featuring 4 songs which are completely different, but equally as powerful. You can picture some of them in very dramatic scenes in a TV or film which is coincidental as Samuel’s music has recently been featured in some big US TV shows such as Satisfaction, Nashville, About A Boy, and Grimm.
Writing would take shape in some form in Samuel’s career even if he wasn’t a singer. He loves making things, cooking, being creative. Before writing music he wrote comedy for a newspaper in London. And this is what he’s so good at; writing lyrics and melodies that come together and that you don’t easily forget. He draws inspiration from many different things. Traveling and living in South Africa when he was young “shaped (his) musical journey which comes across in (his) music.” His time in Johannesburg introduced him to native, tribal, community songs and gospel. He loves the sound of a choir, a lot of people singing together and is a huge fan of BB King, blues and soul classics. All this is apparent when you listen to ‘Let It All Out.’ in fact, it’s amazing to hear so much personal experience and influence poured into one song.
Plans for next year include his tour which is going really well. “Finishing a bunch of writing which will be an album“, and releasing his next single late January/early February and a video following that. He is looking forward to being back on the road and maybe going to the States, a place which he is very fond of.
Samuel is very ambitious and passionate about what he does. He loves playing shows and connecting with people and an audience. He appreciates “people resonating with what you’re writing.” He got an email recently from a lady who wanted to say thank you as his music really helped with a tough time she was going through and that made his year. That’s why he does it and he does it so exceptionally well.


Ace Nigerian media personality Tolu Oniru, popularly known as Toolz, has weighed in on Davido’s recent cheating drama and offered a word of advice to his ex-fiancee, Chioma Avril Rowland.
Speaking on the “Off-Air” show she hosts with OAP Gbemi, Toolz shared a piece of advice to Chioma on how best to deal with the issue of Davido’s cheating.
The media personality said she would have wished Chioma had properly set up herself “business-wise” before her relationship with Davido ended.
Asked if she had any piece of advice for Chioma, Toolz said yes and said her advice to Chioma is that she should get a photographer to follow her around so that she can be dropping the “bombest” pictures on social media.
Watch the video below:


text: The Philadelphia Inquirer reports that Lawrence Berger, associate professor of social work at the University of Wisconsin - Madison, conducted a research study on the health effects of excessive debt. He concluded that too much debt is bad for your health. Specifically, his research found that when the dollar amount of a person's debt increases by 10 percent, depressive symptoms increase by 14 percent. Depressive symptoms include not being able to shake the blues or having trouble eating or sleeping. This should not be a surprising result for those who are buried in bills. This study also found that there is a difference in how too many bills effect younger and older individuals. For adults from 51-64 years old, short term bills, such as credit card debt and payday loans have the greatest impact emotionally. On the other hand, young adults are more troubled by long-term debt, such as student loans.

domain: economics


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A young man's life depicted at three ages.
Directed by Barry Jenkins
Starring Naomie Harris, Mahershala Ali, and Trevante Rhodes
Initial Review by Phil Crone
We all have our criteria for what makes a movie a definitive A+. It could be as simple as just being entertaining. It could be because it has no discernable flaws in a precise checklist. It could be quotability and rewatchability. For me, an A+ is a movie that I keep returning to in my head days and even weeks later, pondering and re-analyzing scenes in my head, finding new takeaways and challenging initial conclusions. I watched “Moonlight” five days ago, and it continues to permeate my thoughts. By my own subjective measure, I believe that makes “Moonlight” an A+. Ultimately, what “Moonlight” does so perfectly is take, on the surface, a very unique and unrecognizable situation and turn that into a universal truth. “Moonlight” is a stark reminder of how much who we are is an influence of who came before us and our intensely human desire to belong and be accepted for who we are.
“You guys didn't like Kyle. That's okay. I didn't either. I loved him. He was my son. But he was also a douchebag.”
During my junior year of high school my friend and classmate, Brandon, shot himself in the head in his ex-girlfriend’s backyard. This was the first time someone I knew (outside of a grandparent) had died. I had no idea how to react or what to do. I just worked the rest of my shift at a local Subway in dismay.
That day, my buddy and my brother picked me up from my shift, I told them about what Brandon did. (This was before texting and everyone having cell phones, so sometimes it took days for news to spread. Crazy.) For some reason, I felt myself smiling as I was telling them. I have no idea why I reacted this way. I knew the moment was big and I was supposed to be solemn, but I think I was overwhelmed by the enormity of the situation.
I have no recollection of The Jungle Book books nor the animated movie from the 90s other than Baloo nearly dies. I wish I knew how true to the original this story was compared to the animated version.
The Jungle Book does a lot of things well. Once you get past the first scene, the CGI is nearly flawless. I’m not sure if my brain needed time to adjust or the CGI legitimately improved, but I was worried for my senses after Mowgli’s first sprint through the jungle. By the end, I hadn’t given the CGI another thought – it was spot on.
The War on Drugs began in 1971 when Richard Nixon went on television and announced that drug abuse was public enemy number one. As it turns out, the greatest enemy in the war on drugs may not be the drugs themselves, or maybe not even the people that perpetuate the buying and selling of these substances. Instead, perhaps the greatest enemy—for sure the greatest disservice to the people of North America—has been the stubborn over-simplification of an incredibly complex situation. The problem is organizationally complex; governmentally complex; and as this week’s film, “Cartel Land” shows, this ongoing (almost) 40 year war is as much a problem of the complexity of human nature as anything else.
They say misery loves company.
Mississippi Grind is a road trip story of degenerate gambler Gerry (Ben Mendelsohn) and his good luck charm new friend Curtis (Ryan Reynolds). Mississippi Grind asks a lot out of the 2 leads to carry the film start to finish by putting them on a road trip never spending too long in any stop and they absolutely deliver. The introduction of Gerry and Curtis is an absolute homerun. Gerry listening to Joe Navarro’s 200 Poker Tells (6.99 for Kindle at Amazon, use the link below) before walking into a casino where he is obviously a regular, his messy hair, his posture, his sad face - the viewer knows Gerry is a lifelong loser before he speaks a word. Our first look at Curtis is a cool confident operator. Reynolds shows through Curtis that he is the best in Hollywood at playing disarmingly charming, entering the poker game as an outsider at a table full of regulars and very quickly wins them over with that charm. After the tourney at the bar, Gerry tells the barman he placed 3rd and immediately bet the winnings on a basketball game showing his addiction, then tells Curtis he placed 2nd, showing his character. The two of them get wasted and bond over a rainbow, and gambling. Curtis is Gerry’s lucky charm and Gerry is a buddy for Curtis to hang out with before Machu Picchu time.
JUST SOME IDIOTS GIVING SURPRISINGLY AVERAGE MOVIE REVIEWS.
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Much was made of last week’s rollout of the DiggBar on the social news site Digg.com with many people saying it will negatively affect the search engine optimization (SEO) of websites because of its URL shortening capabilities.
But in a post on the company’s blog today, John Quinn, vice president of engineering, says that the new service is actually search engine optimization (SEO)-friendly and has managed to increase unique visitors by 20 percent.
"Prior to launching the DiggBar, we reached out to Google and SEO experts to ensure we adhered to the leading best practices, as we framed and linked directly to source content via the DiggBar," wrote Quinn. "This process involved gathering feedback from publishers to ensure the execution was as content-provider-friendly as possible."
In order to make sure the original sources of the content are getting the credit for the traffic when people click on the links on Digg, Quinn said the company has made sure that the links include the original rel="canonical" information signifying that the original URL is the actual version.
Micro-blogging service Twitter recently made changes to its HTML title tags which was expected to increase search engine optimization (SEO).


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Cryolipolysis is undoubtedly one of the biggest sustained trends in body contouring, ideal for removing pockets of body fat particularly in the stomach area, flanks, thighs and backs. This technology is proving increasingly popular with patients and doctors alike because of its low downtime, minimum discomfort and most importantly impressive results in destroying fat cells.
CRISTAL® Cryolipolysis is a non-invasive medical technology designed to select and eliminate fat cells through controlled cooling, without causing damage to the surrounding tissue. The crystallised fat is removed naturally and permanently by the body in the weeks following the session, giving way to enhanced curves.
This innovative technique, which ensures safety and efficiency, is non-invasive and requires no anesthesia. CRISTAL® offers a range of several different applicators to handle all the curves of the body, for both men and women. After 8 weeks, the result is optimal and definitive.
The results are impressive, as Clinical trials have reported a decrease of 20 to 25 percent of fat in targeted areas such as the stomach or thighs after one treatment session, with the optimum results visible from two to three months after treatment.
Don’t wait to find out!

domain: health


text:
"Google Play for Education" Launches for Android Tablets, Targets K-12
November 13, 2013 10:55 AM
comment(s) - last by
Google looks to take on Apple in the education sector
It seems as though many school districts — for
— are looking to add tablets into the classroom to aid in learning. Google is obviously aware of this growing trend and is trying to ensure that tablets running Android OS are on a level playing field with Apple’s iPad — the dominant player in the educational tablet market.
As a result,
Google Play for Education
launches today as a way to distribute educational apps for K-12 classrooms. Google Play for Education aims to make it easy for schools to bulk purchase educational apps and distribute them to students’ tablets via the internet.
While most Android tablet apps get knocked for being “stretched smartphone apps”, Google is pushing hard for developers to optimize their educational suites for 7” and 10” tablet form-factors.
Also, to ensure that Google Play for Education isn’t flooded with a slew of shoddy apps, each educational app must be submitted for approval not only from a Google reviewer, but also an educator. Google doesn’t indicate what the credentials of the “educator” will be, but does note that they will “perform a first-pass qualification of apps, assigning the appropriate subject, grade, and common core standards metadata.”
It will be interesting to see how tablets play out as a tool for learning in the coming years. Curriculums must be adapted to integrate them, and simply throwing technology at teachers and students might not always be the best solution, as
Bill Gates famously stated last year
In an interview with
The Chronicle of Higher Education
in June 2012, Gates stated, “Just giving people devices, that has a really terrible track record. You really have to change the curriculum and the teacher and those things, and it's never going to work on a device where you don't have keyboard-type input.”
This article is over a month old, voting and posting comments is disabled
11/13/2013 12:29:09 PM
Yup... It would be different if we were flush with money, but we obviously arent and wont be for ... possibly our lifetimes.
Total waste of taxpayer money for anything like this. If the goal was there and the infrastructure to replace physical books with a cheap e-reader maybe... A CHEAP ereader.
11/13/2013 12:30:01 PM
I'll just leave this here...
11/13/2013 1:58:44 PM
I think their iPad textbook pricing is rather optimistic and assumes no iPads break during the period.
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The Case for Inclusive Learning Systems Building More Inclusive Learning Systems in Australia
A Wierenga, J Taylor
Dusseldorp Forum | Published : 2015
This research is about engaging more young people in learning through systems designed to work for them. Other research shows that in Australia, approximately one in five young people of high school age is out of school, that another one in five do not want to be there, and meanwhile there are over 900 flexible learning programs educating over 70,000 students each year. These programs can be within, alongside and outside schools. The point of this research is not so much about proliferating programs but about recognising flexible learning options as important and legitimate parts of Australia's education systems. The authors argue that it is time for a national conversation about educati..View full abstract
A project initiated by the Dusseldorp Forum, written by Wierenga and Taylor in 2015, as staff of Dusseldorp Forum.

domain: sociology


text:
Houndstooth Shade Clip Clamp
EarthSeaWarrior blurs the line between dreams and waking life with one-of-a-kind neo-nostalgic pieces created from vintage curiosities. Juxtaposing cherubic innocence with surreal horror or retro reminiscence with bright modern accents each piece in this collection draws the viewer into an unexpected dimension of art appreciation. Add visual interest while challenging the status quo."Vintage gooseneck lampshade turned into a clip clamp. Features push on/off socket, clip clamp with white plastic grip, black and yellow plug, and antique nostalgic light bulb. Features vintage pieces reinterpreted with modern materials and methods. Black and white houndstooth cloth cord measures approximately 10' long. Shade measures approximately 6.5â€ wide. Bulb is antique nostalgic filament (40 watts). Lamp can be used up to 75 watts maximum.
To delve deeper into the EarthSeaWarrior universe, check out our blog."


The ferry VALENTINE, anchored in Wellington harbour, has suffered a mechanical glitch.
A new interisland ferry, leased to ease pressure on the country’s strained supply chain, is too slow and can only make one return sailing per day. The Valentine has been further hobbled in the last week by an intermittent glitch with the ship’s bow thrusters.
The ferry began crossing Cook Strait in December carrying only freight. KiwiRail, which operates the ferry service, secured the replacement vessel when gearbox failure crippled the KAIARSCHI. That left only the ARATERE and KAITAKI on the route, which is an extension of State Highway 1 and a vital link in the already snarled supply chain.
Hauliers are frustrated that the replacement ferry can only ply the route once a day because it takes much longer to load. And the upper decks cannot carry trucks.Industries are crisis planning for disruption as the Covid Omicron variant spreads through the community. Supermarket shelves have been running bare overseas, and there are fears consumer goods could be in short supply. The Government estimates there could be as many as 350,000 workers isolating at any one time. There is also an acute shortage of truck drivers.
Now the freight sector is worried about capacity in carrying supplies between the North and South Islands.
The VALENTINE is less powerful than the other ships in the fleet and so takes between 4-4.5 hours to cross the strait, instead of the usual 3.5 hours.The Valentine was leased to maintain the link between the North and South islands while Kaiarahi is out of action. And there are worries that overnight asphalt resurfacing at at Weld Pass, just south of Blenheim will exacerbate delays.Trucks will have to detour via SH7, the Lewis Pass, for five nights in mid-February.
“The supply chain is already under a massive pressure, but it's going to get even worse potentially in the next few weeks. Reduced sailings are going to impact that,” Nick Leggett, chief executive of Ia Ara Aotearoa Transporting New Zealand, said. ”This is a lifeline. It’s food, but it’s also things like oxygen for hospitals and medicine. You can’t afford to have it severed at a point in a national health crisis."
Leggett said operators are struggling with delays and booking, and found Interislander “very difficult” to deal with.Drivers have complained about losing an entire day waiting for sailings. One operator dropped a trailer full of frozen food in Picton recently at 11.30am and was told it wouldn’t be unloaded in Wellington until 5am the next day, Leggett said.
Walter Rushbrook, Interislander’s executive general manager, said the Valentine had not been operating as scheduled in the last week because of the fault. A spare part was sourced from overseas and flown to New Zealand “as quickly as possible”. “The nature of the fault made it difficult to trace, but it has now been identified,” he said. “Once the part is fitted the ship will return to service, and we hope to have Valentine back in operation next week.”Rushbrook said the company is “conscious of the vital role the Interislander ferries play in New Zealand’s supply chain.” In order to maintain freight volumes Aratere and Kaitaki have been making extra sailings, he said. Only one ship can berth at a time in Picton’s port.
“VALENTINE has a larger freight capacity than our current ships, so we have the option of undertaking either two return trips with smaller loads or one return trip per day with a very large load, which, of course, means longer loading and unloading times,” he said. Rushbrook said the VALENTINE carries mainly trucks. “Trucks are not carried on the upper two decks. This is because of the height clearances on those decks, not because of any stability issues.” The upper decks are used to carry “loose cars” being transported to car saleyards.
Source : Stuff


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United puts final touches on major 737 order-sources
By Kyle Peterson | WASHINGTON (Reuters) – United Airlines is putting the finishing touches on an order for at least 100 Boeing Co 737 narrowbody jets potentially worth $10 billion at list prices, industry sources said on Thursday.
United puts final touches on order for 100 Boeing 737 jets
Air Lease Nears Deal to Buy Boeing 737 Max Jets
Air Lease Talks With Boeing to Explore Orders for 737 MAX Jet


Jadon Sancho arrived at Manchester United in 2021 as a highly-rated youngster. The hype was seemingly justified after finishing the previous season as one of the Bundesliga’s top attackers. Alongside the return of Cristiano Ronaldo, he symbolized the Red Devils’ return to the toast of the English top flight.
However, things haven’t been as rosy since that summer of 2021 for United fans. United talisman Ole Gunner Solskjaer was replaced by Erik ten Hag in the trenches. Ronaldo’s second stint at Old Trafford ended in a nightmare after his interview with Piers Morgan saw his contract with the team terminated.
Moreover, Sancho couldn’t live up to the €85 million transfer fee in his debut Premier League campaign. Things improved for him at the start of his second season at Old Trafford. However, OKBET players who follow the Premier League know he’s not a permanent fixture in ten Hag’s XI.
Sancho is no longer viewed as the superstar that commanded such a high price in 2021. However, everyone knows he can thrive in a tough European league. What he needs is to rediscover his form.
This piece will look into the possible reasons for his struggles in his Premier League journey. We’ll also consider what Sancho should do to get back into his peak form that convinced United to splurge for his services.
On paper, Manchester United’s 2020/21 squad featured world-beaters that should give cross-town rivals Manchester City and Liverpool a run for their money.
The Red Devils last season featured outstanding creators in Paul Pogba and Bruno Fernandes. The two were supposed to provide opportunities for Sancho to cut through Premier League defenses with his runs.
However, it was noticeable that Sancho struggled to make his mark in his first year at Old Trafford. He finished his maiden Premier League campaign with only three goals and three assists in 29 league appearances. It was a shocking decline to his last season in the Bundesliga, where he bagged eight goals and 11 assists in fewer appearances.
The biggest reason for his lack of production in the league was an evident lack of playmakers who could place him in dangerous situations. There was a wealth of playmaking talent during his final Bundesliga campaign. Marco Reus, Raphael Guerrero, and Giovanni Reyna were some of the players who could provide key passes in dangerous areas.
On the other hand, there was an obvious lack of creativity in United’s midfield. While Pogba topped the team with his nine assists, everyone could tell that the France international was out of sorts with the squad. Pogba made it clear in his Amazon Prime documentary that his second stint at Manchester United ended sourly.
The lack of effective passers was also evident in Sancho’s scouting report for the 2021/22 season. He had 0.19 non-penalty xG per 90, 0.14 assists per 90, and 4.17 shot-creating actions per 90. These were noticeably lower than his 2020/21 campaign numbers.
Sancho actually started the following season right for United. He featured prominently during the team’s preseason matches. He also had two goals in United’s first five league matches.
However, people were quick to point out that his form quickly sunk after he was snubbed out of the England squad during the leadup to the World Cup.
Gareth Southgate chose to go in a different direction regarding the Three Lions’ attack, opting for Arsenal’s Bakayo Saka to line up alongside Harry Kane. While England suffered a quarterfinal exit to France, Saka’s blossoming in the national team setup seemingly justified the head coach’s decision not to call Sancho up.
Ten Hag also revealed that the player wasn’t in his best shape as the league resumed on Boxing Day. The Manchester United manager detailed that the player is on a strict individual training regimen in the Netherlands to get him back on track.
While he doesn’t expect Sancho to return soon, he hopes to see him at full fitness immediately. After Ronaldo’s departure, the squad lacks attacking options. Moreover, Anthony Martial and Marcus Rashford are the team’s only options up front. The team needs him back as quickly as possible to help fight for a top-four finish.
It’s tough to say whether Jadon Sancho will be able to return to the form that caused Europe’s top clubs to line up for his signature. Everyone can see that his struggles are a mix of physical and mental problems, and the club can only do so much to help him get back on his feet.
It’s up to him whether he’ll get his form back on the right track. Manchester United’s current predicament is the perfect time for him to get back to his winning ways and endear himself to the Red Devils faithful.
Read more: Naomi Osaka Announces She’s Pregnant!


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Koster Stockyard has all the supplies you need to keep your land or garden in place during wet weather. Home gardeners can improve drainage in and around gardens and flower beds, paths and terraces. For the contractor, we have the products you need in the amounts, lengths, and quantities to do any project. We welcome inquiries from landscapers and large scale commercial contractors.
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- HDPE Drainage Culverts
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See our Landscape Supply page for a full description of the types of gravel and stone and their uses for erosion control and other uses.

domain: agronomy


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Mike Noble, celebrated comic-strip artist on TV21 (Zero X, Fireball XL5, Captain Scarlet and Star Trek) and comic-strip artist Lee Sullivan (Doctor Who, Transformers, Thunderbirds Magazine) have combined forces to produce a jointly signed limited print artwork to coincide with the first Andercon convention held in 2014.
Mike was keen to see what digital art techniques could be used to compliment his own immaculate traditional style, and supplied artwork of the craft shown which Lee then combined with a digital painting he created of the Orion Nebula.
When both artists were satisfied with the results, a giclee print on heavy matt paper was created with a limited print run of 100 prints worldwide.
The print measures approx. 18.5 x 13 inches (48 x 33 cm) with image area of 15.75 x 11 inches (40 x 28.5 cm).
Each print is individually numbered and signed by both artists and will be mailed in a strong cardboard tube.
Zero X is a fictional Earth spacecraft that appeared in two of Gerry and Sylvia Anderson's Supermarionation productions, the 1966 film Thunderbirds Are Go and the 1967 television series Captain Scarlet and the Mysterons. Although publicity material for the various Supermarionation series, and the TV Century 21 comic, made references to connections between the Thunderbirds and Captain Scarlet canons, Zero-X is the only official link between the two series.
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Neuroscience Research Australia is part of a bold new idea in medical research that sees 11 research institutes, hospitals and universities form Australia's first Health-Science Alliance.
A new NeuRA study has found that people suffering from depression are more likely to fall, pointing to a complex relationship between mental illness, a sense of balance, and falling in older people.
HAWAII--The environment in which laboratory mice are reared can drastically alter the results of experiments and may have major implications for medical research around the world, according to new Aus
Improving the quality of information available to culturally diverse families across NSW may improve child vehicle safety across the state, according to new research.
Ever been stuck in traffic when a feel-good song comes on the radio and suddenly your mood lightens?
The Southern Highlands community got an opportunity to learn about the latest research into Parkinson's disease when three NeuRA experts held a free talk on Wednesday 30 May.
Our ability to imagine and plan our future depends on brain regions that store general knowledge, new research shows.
Prof Cyndi Shannon Weickert, a widely-recognised trailblazer in the neuroscience of schizophrenia, has been appointed to the board of the Society for International Schizophrenia Research.
Stephanie woke one Saturday morning to find that she couldn't speak properly and collapsed shortly after having suffered a major stroke, at the age of 22.
An Australian research team examining the care of hip fractures in older people has just secured highly competitive funding to investigate this growing problem.
The NeuRA Profile 2012 is now available online. We invite you to explore highlights of our research and discoveries.
Dr Penelope McNulty, senior researcher at Neuroscience Research Australia (NeuRA), will lead a project investigating the delivery of Wii-based Movement Therapy via the NBN in several sites across NSW.
This week Australian bridge players will be using their brains to raise much-needed funds for Alzheimer's and dementia research.
The La Perouse Aboriginal community will be celebrating National Close the Gap Day on Thursday 22 March 2012 with the launch of a new project to facilitate access to dementia care for Aboriginal pe
The Australian Story documentary featuring NeuRA's Prof Cyndi Shannon Weickert will be broadcast on ABC News 24 this month.
You – or more accurately, your brain – has control over how allergic your skin is, suggests new research.
Two genes related to protein accumulation in the brains of people with Parkinson's disease can indicate how quickly the disease will progress in an individual, say NeuRA researchers.
The Federal Health Minister, Tanya Plibersek, announced today that NeuRA researchers have been awarded government grants totalling $18 million.
New studies on how phantom limbs form show there is no default position that the phantom moves into after it forms.
Falls expert Dr Kim Delbaere says the key to preventing falls in the elderly is to encourage grandma and grandpa to embrace the latest technology and video games.

domain: medical


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by Anthony Gucciardi
November 6, 2011
Through the mass genetic modification of
nature via GMO crops, animals, biopesticides, and the
mutated insects that are created as
a result, mega biotechnology corporations are threatening the
overall genetic integrity of the environment as well as all of
As the production and consumption of GMO crops continue to soar, it
is becoming increasingly apparent that consumers worldwide are
unknowingly participating as ‘test subjects’ in a massive experiment
on the long-term effects of GMO crops and ingredients.
In fact, nearly
93% of U.S. soybeans are genetically
modified in order to resist powerful weed-killers that were found to
be killing the actual soybeans as well as the weeds. So it turns out
that the weedkiller was actually strong enough to kill the soybeans,
yet it is considered safe for consumption.
After the genetic alteration, these
powerful weed-killers now simply drench the genetically modified
The Dangers of
GMO Crops, Biopesticides, and the Threat of Mutation
Besides the weed-killers, GMO crops themselves are also endangering
your health even without pesticides.
review of 19 studies announced that
consumption of GMO corn or soybeans may lead to significant organ
disruptions in rats and mice - particularly in the liver and
kidneys. The researchers also mentioned that GMO soybean and corn
varieties contribute to “83% of the commercialized GMOs” that you
may currently be consuming if you purchase conventional produce.
Following current trends, genetically modified food products will
makeup the majority of the future food supply if a change is not
Statistics show how GMO crops and ingredients have skyrocketed
in even the past few years.
Of course organ disruption is not the
only side effect of GMO consumption, or even the most startling.
threat to nature, your body, and the entire ecosystem is what is the
Genetically modified mosquitoes,
funded by the owner of
500,000 Monsanto shares
Bill Gates, were recently
unleashed into the environment to freely interact with regular
insects. Of course the release was toted as an amazing method of
combating the growth of the mosquito population and the subsequent
spread of disease.
The study involved about 19,000 genetically modified mosquitoes
which were released in the Grand Cayman Islands over a 25-acre area
for four weeks.
In addition to the genetically modified mosquitoes, other insects
actually developed mutations in
Bt exposure - a toxin used in GMO crops as a
biopesticide. As many as 8 populations of insects have developed
resistance as a result, with 2 populations resistant to Bt sprays
and at least 6 species resistant to Bt crops as a whole.
So not only are the crops causing
mutations, but as a result biotech scientists are now even further
modifying Bt to be even more potent. In tests, however, the insects
still were able to mutate and resist the disease.
Just as the scientists did not expect the insects to mutate to the
point of complete immunity, there may be many other consequences as
a result of GMO crops and biopesticides.
And for what?
The very same study also took time to mention how alternative and
sustainable forms of organic farming should be utilized. The study
Alternative organic, sustainable methods of farming provide a
realistic alternative, independent of reliance on agrobiotech
This is why nations around the world are banning and uprooting GMO
crop fields, thereby putting an end to the genetic manipulation of
the planet before the proverbial roots of genetically modified
creations dig too deep.
Hungary has led the charge,
destroying 1000 acres of maize
found to have been grown with genetically modified seeds. Peru has also passed
a monumental 10-year ban on GMO foods.
Through spreading information and speaking out, GMO crops and
biopesticides are being phased out and even banned in some
countries. Even small amounts of activism can result in major


text:
WEDDING AT NOKKA
* Valid till 22.12.2020
The lovely and romantic atmosphere at Restaurant Nokka is ideal for wedding celebrations. We have many spaces available for the weddings, max 100 persons. Our kitchen offers always the season´s best ingredients available. We will happily tell You more and help to organize the most important day of Your life! Please contact us
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Juniper salt cured white fish with pickled vegetables and mustard sauce
Wild reindeer from Salla with puikula potatoes and black currant
House wine (two glasses, á 12cl), coffee/tea, water, cloakroom service
We offer always the season´s best ingredients available. Ask more about season´s menu. Restaurant Nokka has many spaces available for the weddings, max 100 persons.

domain: food