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Increasing TIMP3 expression by hypomethylating agents diminishes soluble MICA, MICB and ULBP2 shedding in acute myeloid leukemia, facilitating NK cell-mediated immune recognition
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Aroa Baragaño Raneros1, Alfredo Minguela2, Ramon M. Rodriguez1, Enrique Colado3, Teresa Bernal3, Eduardo Anguita4, Adela Vasco Mogorron2, Alberto Chaparro Gil4, Jose Ramon Vidal-Castiñeira1, Leonardo Márquez-Kisinousky1, Paula Díaz Bulnes1, Amelia Martinez Marin5, Maria Carmen García Garay6, Beatriz Suarez-Alvarez1,*, Carlos Lopez-Larrea1,*
1Department of Immunology, Hospital Universitario Central de Asturias, Oviedo, Spain
2Immunology Service, Instituto Murciano de Investigación Biosanitaria (IMIB), Hospital Clínico Universitario Virgen de la Arrixaca, Murcia, Spain
3Department of Hematology, Hospital Universitario Central de Asturias, Oviedo, Spain
4Hematology Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Department of Medicine, Universidad Complutense de Madrid (UCM), Madrid, Spain
5Hematology Service, Hospital Clínico Universitario Virgen de la Arrixaca, Murcia, Spain
6Hematology Service, Hospital General Universitario Santa Lucía, Cartagena, Murcia, Spain
*These authors have contributed equally to this work
Carlos Lopez-Larrea, email: firstname.lastname@example.org
Beatriz Suarez-Alvarez, email: email@example.com
Keywords: acute myeloid leukemia (AML), DNA methylation, NKG2DL, NKG2D, TIMP3
Received: September 16, 2016 Accepted: March 16, 2017 Published: March 29, 2017
Acute myeloid leukemia (AML) is a disease with great morphological and genetic heterogeneity, which complicates its prognosis and treatment. The hypomethylating agents azacitidine (Vidaza®, AZA) and decitabine (Dacogen®, DAC) have been approved for the treatment of AML patients, but their mechanisms of action are poorly understood. Natural killer (NK) cells play an important role in the recognition of AML blasts through the interaction of the activating NKG2D receptor with its ligands (NKG2DL: MICA/B and ULBPs1-3). However, soluble NKG2DL (sNKG2DL) can be released from the cell surface, impairing immune recognition. Here, we examined whether hypomethylating agents modulate the release of sNKG2DL from AML cells. Results demonstrated that AZA- and DAC-treated AML cells reduce the release of sNKG2DL, preventing downregulation of NKG2D receptor on the cell surface and promoting immune recognition mediated by NKG2D-NKG2DL engagement. We show that the shedding of MICA, MICB and ULBP2 is inhibited by the increased expression of TIMP3, an ADAM17 inhibitor, after DAC treatment. The TIMP3 gene is highly methylated in AML cells lines and in AML patients (25.5%), in which it is significantly associated with an adverse cytogenetic prognosis of the disease. Overall, TIMP3 could be a target of the demethylating treatments in AML patients, leading to a decrease in MICA, MICB and ULBP2 shedding and the enhancement of the lytic activity of NK cells through the immune recognition mediated by the NKG2D receptor.
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domain: literature


“They might go to jail, but they get out right away,” Mark Martello said, following a game with what he believed to be a lack of fouls against Portland State. “They can get away with it.”
Martello—who was running the play-by-play commentary for the game—said this after a Montana State Bobcats player was fouled several times, according to The Blaze.
“Evidently, ‘Cats are up 19, Portland can get away with whatever they’re going to get away with,” Martello said. “Portland’s like Antifa after a riot. They might go to jail, but they get out right away. They can get away with it.”
Joe Terry of Big Sky Valhalla tweeted about Martello’s words the day of the game, and copied Montana State’s director of athletics.
After a no call on the MSU end, the Cats pxp guy takes an interesting tact on the call:
“Portland can get away with whatever they want to get away with. Portland’s like Antifa after a riot. They might go to jail but they get out right away.”
— Joe Terry (@joseph_terry) January 22, 2022
The following day, Terry tweeted that he heard Martello had been fired.
Getting word that the MSU announcer for the game was let go. Unsure if Montana State will comment on the situation. https://t.co/g1H4cq0BEI
— Joe Terry (@joseph_terry) January 23, 2022
Martello told 406mtsports.com that he was fired because of Terry’s tweets.
“I am taking responsibility for what came out of my mouth,” Martello texted to 406mtsports.com. “I will miss the team and coaches. There will be no apology, no one was harmed.”
In a press release, MSU said Martello “has been removed from Montana State’s radio broadcast team” and the decision was made by the LEARFIELD broadcasting company.
No reason was given for his dismissal; both LEARFIELD and ESPN declined to comment.


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Many of Victoria’s greatest food and wine experiences can be found outside of Melbourne’s city limits. From world-famous Brae in Birregurra to the award-winning Argus Dining Room in Hepburn Springs and trailblazing Igni in Geelong, regional Victoria’s dining scene is an ongoing celebration of the state’s lauded food producers and inventive chefs.
A trio of new and refreshed properties in regional Victoria are giving local and international visitors a good reason to plan a gastronomic getaway.
An outdoor art gallery, cellar door with water views and restaurant run by a culinary director with a serious pedigree combine to create one of the most exciting new openings to hit the Mornington Peninsula. Opened in October 2017, this multimillion-dollar sculpture park, cellar door and restaurant is easily accessible from Melbourne making it one of Victoria’s hottest new getaway destinations.
Under the guidance of culinary director Phil Wood (ex Rockpool and Tetsuya’s) the restaurant offers a dining experience rich with the flavours of regional Victoria. Cape Schanck olive oil, Yarra Valley trout roe, Flinders mussels and local honey and cheese all feature on the menu served in a classy dining room designed to showcase views of the surrounding vineyard.
Open daily from 11am - 6pm, the open-air sculpture park allows visitors to take in local and international works of art amid a scenic backdrop of grapevines, grazing cattle and native flowers. Short and longer walks ensure visitors of all ages can wander the sculpture park, taking in the oversized works made from ceramic tile, wood and metal.
The great Mornington Peninsula drops (chardonnay, pinot gris and pinot noir) are all available to sample and purchase at Point Leo Estate’s cellar door. Guests can choose to sip wine on the terrace while enjoying the views or visit the cellar door to purchase a few bottles to take home – either way Point Leo Estate is the type of place visitors can choose to drop into for an hour or settle in for an afternoon of art and gastronomy.
3649 Frankston - Flinders Rd, Merricks. Tel: +61 3 5989 9011
Opened to the public in December 2017, the $16 million Mitchelton Hotel and Spa represents a significant boost for the Goulburn Valley region which is only 90 minutes from Melbourne. Located on the banks of the Goulburn River, the new hotel from the team behind Mitchelton Wines provides visitors with a luxe spot to bed down in between wine tasting at the on-site cellar door, exploring the town of Nagambie or venturing out to the wetlands for a bird spotting session.
Featuring 58 rooms and suites, the new hotel’s warm linen, leather and timber furnishings create a welcoming space for visitors to retreat to. Commissioned works by Melbourne-based artists Trevor Mein and David Band feature throughout the property, with mod cons such as Bose sound systems and a 20m infinity pool enabling guests to relax in style.
470 Mitchellstown Road, Nagambie. Tel: +61 3 5736 2222
While a well-established giant on the Australian dining scene, the Royal Mail Hotel has recently been refreshed with extensive renovations breathing new life into this much-loved property that has put the small town of Dunkeld back on the map.
Featuring unobstructed views of Mt Sturgeon and Mt Abrupt, the new restaurant named Wickens at Royal Mail Hotel broadens the scope of what has traditionally been offered at the Royal Mail Hotel. The tasting menus feature produce that is harvested by the chefs daily from the kitchen’s garden - the largest working restaurant kitchen garden in Australia. Dairy, fruit, beef and lamb sourced from local farmers can also be found on the menu.
The revamp also includes updates to the menu and interiors of casual eatery, Parker Street Project, the development of a new wine bar showcasing some of the region’s finest drops, and renovations to the reception area where a guest lounge and retail space enables guests to linger a little longer or purchase a slice of the Royal Mail Hotel to take home.
98 Parker Street, Dunkeld. Tel: +61 3 5577 2241
This content can be shared and edited for the purpose of promoting Victoria as a visitor destination. Not for use in paid advertising. Please credit Visit Victoria.

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Experienced technicians must have a minimum of 3 years experience troubleshooting and repairing gas boilers and furnaces, air conditioning , oil furnaces and boilers, heat pumps. Candidates must have a valid MA Gas Fitters License and MA Oil Burner License. Refrigeration License and NH Gas Fitters License a plus. Candidate must also participate in rotating on call schedule during the Fall-Spring and must have a valid driver’s license with a clean driving record.
Candidate will be responsible for the installation of residential heating and air conditioning equipment. Qualified candidate will have a minimum of 3 years experience installing gas and oil-fired heating equipment, central a/c and mini-split a/c. Candidate must ensure that the job is installed “to code” and within the time frame established for the job. Candidates must have a valid MA Gas Fitters License, MA Oil Burner License, MA Sheet Metal License and Refrigeration License. NH Gas Fitters License a plus. Must have valid driver’s license with a clean driving record.
Candidate must have a minimum of 3 years experience with all facets of residential plumbing including hot water boiler and water heater installations. Must know all applicable codes for new construction. MA Plumbing License required, NH Plumbing License a plus. Must have valid driver’s license with a clean driving record.


• March 11, 2019
Auckland Transport is planning to drop the speed limit to 30k/hr on many Auckland roads.
Auckland residents have until the end of March to have their say on Auckland Transport’s proposal to lower speed limits on some of the city’s roads.
Nine people have died on Auckland roads so far this year, according to the Ministry of Transport. AT says reducing speed will create safer roads around Auckland.
Joanna Glasswell, an AT senior media advisor, said AT was proposing to reduce speeds on approximately 10 per cent of Auckland’s roads. "Most of these are in rural areas, but the proposal also includes the city centre and some town centres where there are lots of people walking and cycling.”
In a media statement, AT chairman Lester Levy said Auckland was facing a road safety crisis. "Our top priority is to address this.”
Dr Levy said lowering the speed limit - to as low as 30km/h in some instances - is the most effective way to create safer roads.
Barney Irvine, principal advisor at the New Zealand Automobile Association, said 30km/h was not an appropriate or credible speed limit for the CBD and 40km/h would be better.
“40km/h is what the Transport Agency has recommended the safe and appropriate speed for central roads in the city.”
Auckland resident David Knepschled supports the proposal: “I think it’s good in the city to lower it to 30km/h but in rural areas, I don’t think it’s necessary.”
Another Auckland resident, Tarena George-Kumar, said: “It’s dumb isn’t it…I see the point, but is it really a good move?”
In a media statement, AT chief executive Shane Ellison said: “We appreciate that some parties believe 30km/h is too slow and that 40km/h is more appropriate, however, our first priority is peoples’ lives.”
The roads chosen for speed reductions are those with the greatest safety risk and a history of accidents and deaths.
Mr Irvine said: “Before we jump to reducing speeds on those arterial roads, let’s have a really good look at what can be done to maintain the current speed of those roads but improve the engineering of the roads so that the road environment is safer.
“You can change the speed limit but getting people to comply will not just be difficult but impossible,” he said.
The road safety programme is partly funded by the Regional Fuel Tax. Find out more about the proposal here:
Road death statistics:


Last semester I visited Elizabeth de la Reguera’s study sites on the Eastern Shore of Maryland. We prepared and planted small research plots with switchgrass, barley and wheat. Elizabeth is studying the effects of saltwater intrusion on crop productivity and survival. Over winter break, I continued to work on this research by gathering data on how well the different plant species were growing in each plot. The AgroEcoLab manager, Cullen McAskill, gave me hundreds of pictures from the site, and I got to work! Cullen had placed a quadrat on the plots in the fall, so that we could determine the species of different plants within a grid. Imagine trying to count each plant individually in each plot! Instead, the quadrat is placed at each plot in random so that it isolates an area that can then be used to represent how much of that plant species is in that plot. My job was to take each picture individually with the quadrats and set a scale in which we would tell the program, SamplePoint, to count how many plants were within those quadrats. Gathering all this data will not only tell us what species is doing the best or worst in salty conditions, but it will also provide us with the information we need to improve any management techniques in the future.
-By Karla Rosales Lobos
On Tuesday, 9 Jan, the AgroEcoLab's work on saltwater intrusion was featured in Maryland Public Television's weekly show, Maryland Farm and Harvest.
Check out the full video here.
A few weeks ago, I visited the experiment that Elizabeth de la Reguera has established for her Master’s degree at the University of Maryland. The question for her experiment is, what is the effect of saltwater intrusion on the productivity and survival of different plant species? We travelled to Eastern Shore of Maryland to till her plots and plant switchgrass, barley, and wheat. We used rakes to till the plots because we did not want to till too deeply, which would degrade the soil. We only needed to ensure good seed-to-soil contact, to help the plants germinate and prevent them from being blown away by the wind (grass seeds are REALLY small). Then, each type of seed was assigned to one person to disperse on the plots. The purpose of this is to have some kind of uniformity when it came to the dispersion of the seeds. While we were there we took water samples from the lysimeters that Elizabeth had already installed. When we came back from field, I started to measured the porewater conductivity and pH. The soils and porewater have high electrical conductivity, which is likely due to the high levels of chloride and sulfate moving into the plots with saltwater.
- By Karla Rosales Lobos
It is important to remember that agricultural systems are ecosystems themselves, albeit human-created, and are not closed to the surrounding environment. This is fundamental to understanding why agroecology is so important, as it addresses the balance between human well-being and
environmental health. Excessive nutrient application to agricultural fields poses serious risk to the surrounding aquatic ecosystems in the watershed, for too much nutrient runoff into water bodies can trigger a cascade of events that eventually depletes all or most of the oxygen in the water. This process is called eutrophication, and not only is it is toxic to fish and all oxygen- requiring life present in the water, it is also harmful to humans who depend on these ecosystems for harvesting food (Howarth 2008). By understanding how to best manage the balance between nutrient application and cover crop usage, farmers can make the most sustainable choices to both protect the environment and preserve their own livelihoods as well as those of future generations.
- By Alexis Boytim
Howarth, Robert W. 2008. Coastal nitrogen pollution: A review of sources and trends globally and regionally. Harmful Algae, (8): 14-20.
Di, H. J., K. C. Cameron. 2002. Nitrate leaching in temperate agroecosystems: sources, factors, and mitigation strategies. Nutrient Cycling in Agroecosystems, (46): 237-256.
A couple weeks ago, I went on a field trip for my Wetlands Ecology class to learn about different types of wetland ecosystems. We followed the Patuxent River along a salinity gradient from freshwater (less than 0.5 parts per thousand (ppt) salinity) near the head of the river to salt water towards the mouth of the river, which drains into the Chesapeake Bay. The first stop was at Patuxent Wetland Park, a freshwater wetland. We saw firsthand the ways that wetland plants adapt to the stresses of a low oxygen environment. Soil is a mixture of particles separated by spaces called pores. In many ecosystems, these pores are filled with a mixture of water and air. In wetlands, these pores are frequently or permanently filled with water and plant roots cannot acquire oxygen through them. Therefore, they have special adaptations to fill their oxygen needs. For example, the water lily uses aerenchyma, or spongy tissue with air channels to pipe oxygen from above the water table down to its roots. Our second stop was at the Clyde Watson Boating area where the salinity ranged from about 5 to 7.5 ppt. We noticed salt buildup on the leaves of many of the plant species here. These plants adapt to saline conditions by extruding salt through specialized glands. It was a hot day and everyone decided to cool off in the river in their full chest-wader getups. The third stop was a salt marsh at Island Creek Marina where the salinity ranged from about 10 to 12.5 ppt. Here I spoke to the class a bit about my work in these ecosystems. We passed around a soil sample for everyone to smell the hydrogen sulfide produced by the specialized microbes that colonize salt marsh soil. I knew the rotten egg smell well from this past summer’s research and I felt right at home as I excitedly nerded-out to the class about redox conditions. At each of these sites, we split into groups and took a vegetation survey using a PVC quadrat. This allowed us to determine the dominant plant species present in each wetland type. We noticed how dramatically the plant species composition shifted with these salinity changes. Specifically, plant biodiversity dropped sharply as salinity increased from site to site. As an impromptu final stop, the group decided to check out Battle Creek Cypress Swamp, which contains one of the northernmost stands of Cypress trees in the United States. We noticed the stubby cypress “knees,” or part of the roots that sit above the water line. Though their function is not entirely confirmed, researchers think that the knees help to bring air down to the lower parts of the plant roots. We took a walk across the swamp on a beautiful newly build boardwalk. I also got to collect some edible fruits from the native Pawpaw tree as we strolled along. Despite being completely covered in mud at the end of the day, I was so happy to spend my Saturday outside learning about these very unique ecosystems!
- By Dani Weissman
In early August, Bri and I attended and presented our research at the national Ecological Society of America conference. This was a great opportunity for us to present our research to ecologists throughout the country. From Monday through Friday of the conference, there were talks scheduled throughout the entire conference center. I was amazed by the wide array of topics; there was everything from biogeochemistry to conservation management to population and community dynamics. We used the very handy ESA program app to sort through the talks and find the ones that best fit our interests. Consequently, we also found ourselves running laps through the convention center to try to see everything! I also jumped outside of my familiar realm of soil science and nutrient cycling to attend a symposium on trophic cascades as they relate to the reintroduction of wolves in Yellowstone. It was very fun to explore a different facet of ecology. There were also some very interesting exhibitors at the conference as well. We stopped by the Union of Concerned Scientists table and learned about how science can be better promoted and used to drive policy.
On Tuesday, August 8, I spoke on my work on saltwater intrusion and nutrient cycling in coastal agricultural areas. Later that week, Bri presented her work on cover crops and nitrogen leaching in agricultural systems. On Friday of that week, I moderated a session organized by Kate on sea level rise and ecosystems services. The session was comprised of five very short (<5 minute) talks from different researchers followed by a lengthy discussion period. The speakers gave a lighthearted bend to a very serious topic by dotting their talks with silly limericks and jokes. I think we all may have been a little worn out by the end of the week!
As we were bustling about the convention center, everyone couldn’t help but notice the layer of smog that hung over the city of Portland for the entire week and obscured our view of the beautiful mountains. This was due to smoke traveling south from forest fires raging in nearby British Columbia. I made the immediate connection between the environment outside and the work presented at the conference. Ecological research has such a pressing importance in our daily lives. Climate change and human activities will most certainly alter the range, frequency, and intensity of these fires, as well as many other earth processes. I left the conference with a sense of encouragement—it was wonderful to see so many dedicated researchers working towards an overarching goal.
- By Dani Weissman
As we set out on our last porewater sampling trip of the 2017 summer, I get a bittersweet feeling. I’m happy about all the progress we’ve made on Dani’s saltwater intrusion project, and proud of all I have contributed to the study, but I know I’ll miss spending every other week on Maryland’s beautiful Eastern Shore. Over the summer I have met some awesome people, and I’m grateful that half the time “another day at the office” meant knee-high boots and a machete, but I think I’ll miss the marsh wildlife the most.
Growing up I was always outside looking for snakes, frogs, and bugs, and when I had to be inside I was watching animal planet or reading National Geographic. I left no stone unturned…literally. Instead of growing out of this fascination with life, I only became more interested as I got older, and now I own field guides for just about any critter in North America. The marsh and forests on the shore are rich with animals, and participating in this study was a perfect opportunity to pursue my love for environmental science, and to get up close and personal with the fauna. I must say the mosquitos, deer flies, and chiggers got a little too up-close and personal at times, but it was all worth it. After four water sampling trips and a soil sampling “campaign,” I think we all were starting to feel like marsh wildlife ourselves.
Working with the AgroEcoLab has been an amazing experience, and I look forward to continuing our work into the fall semester, but I will miss the wildlife of the Eastern Shore. In all we’ve rescued four turtles in the middle of the road, hopefully that’s enough good karma to last us until we can get back down there.
- by John Dietrich
I have been working in the Agroecology Lab for almost a year now researching the movement of nitrogen through the soil profile and into cover crops. In this time, I have installed instrumentation in the field, processed data using a combination of R and excel, and collected over a thousand soil and plant samples.
Our instrumentation includes lysimeters and Time-Domain Reflectometers (TDR). Lysimeters are used to collect porewater samples, which we use to quantify nitrate and ammonia concentrations 60 cm down the soil profile. This will give us an idea of how much nitrate-N is leaching out of the system. Our TDR’s are used to measure soil temperature, volumetric water content, bulk relative permittivity, electrical conductivity, and soil pore water electrical conductivity at 0-10 cm, 20-30 cm, and 50-60 cm down the soil profile. The TDR’s were installed for approximately 4 months and collecting data every 10 minutes yielding 252, 870 data points. This forced me to quit using excel all together and familiarize myself with R Studio. Data processing in R Studio has been a wonderful, rewarding experience.
Over 900 soil samples sounds quite intimidating. However, we processed all of our soils shortly after the collection date, so it was quite manageable. Unfortunately, some sources of contamination are entirely unexpected and are left undiscovered until the data processing stage. Four of our sampling dates had unusually high levels of ammonia. Contamination is part of working in a lab and is something we are all very careful about. After a while we discovered the potential source of contamination: our filter papers. I rummaged through my archived soils and began the process all over again. Luckily, with the help of our amazing lab crew: Cullen, John, Gabe, and Tony we were able to complete all 900+ extraction in seven days!
- By Josh Gaimaro
Dr. Kate Tully
Kate is an Assistant Professor of Agroecology at the University of Maryland.
Dani is a PhD student in the AgroEcoLab and studies the effects of sea level rise on coastal farming communities and estuarine biogeochemistry.
Resham is a PhD student in the AgroEcoLab and studies how to improve water and nutrient use efficiency in cover crop systems.


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Sistema Microwave Collection Rice Cooker, 87.2 oz./2.6 L, Red
Lenox Butterfly Meadow 12-Ounce Dessert Bowls Set of 4
The Edgar Rice Burroughs Collection (30 classic novels all with an active Table of Contents)
Rice and Peas for the Soul 1 : A Collection of 150 Motivational, Inspirational and Moral Stories to Make You Think, Reflect and Wonder
Rice and Peas for the Soul (2) : A Collection of 100 Motivational, Inspirational and Moving Stories That Reassure, Empower and Engage
Do you know where rice come from? I visited my family in Sultan Kudarat, Philippines. It's a rural area where most of the land is used for farming. The main crop grown is rice, and during my visit I was able to observe rice being planted and harvest. It takes 3 months to grow rice. The lan...
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Crumpton took a job selling insurance on commission for Prudential. She worked nights, while her parents watched her daughter. It took more than four years for the family to financially recover from the hit—to move into their own home and for Crumpton to find a better-paying job in a different field at a savings and loan.
Her daughter, now the mother of two, didn’t want to talk on the record for this story. But Crumpton recalls that, at the time, her child “didn’t seem to realize the extent of what was going on—that her mom was unemployed and hanging out.”
Yet, the lessons from that 1980s recession shaped the family’s dynamic for years to come, as it could with Tessa and Dasia. Crumpton urged her daughter to work throughout college so she could avoid taking on student loans. She encouraged her to study science rather than social work or liberal arts, thinking that would give her daughter a more stable career path. Now, her daughter works in as a lab supervisor; she’s been there for 15 years since graduating with a biology degree in 1997.
Crumpton still remembers that tough period of her life, even though she remarried in 1990; moved toWisconsin; and now holds a stable job as a manager at the Consumer Credit Counseling Service of Greater Milwaukee, where she runs daily operations, writes a blog, and gives workshops on managing money.
“It was scary. I remember feeling awful,” she says about that time. “I’ve always taught my daughter to be a saver, because you never know what’s going to happen.”
Crumpton’s story ultimately took a better turn, but her experience wasn’t unusual, then or now. The current crisis has forced young people to move back home with their parents, accept dead-end jobs, and postpone major life decisions such as getting married, having children, or buying a home, according to polling by the Pew Research Center.
How long this generation, waylaid by the Great Recession, will continue to struggle and whether the experience will leave these young people more resilient or more vulnerable economically are unknowns for now.
In 2004, according to Pew data, 56 percent of unemployed 18-to-34-year-olds said they did not have enough income to lead the life they wanted. By 2011, that number jumped to 80 percent.


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- 15 (0.125 EFTS)
- To enable students to examine and reflect upon the historical development of theatre languages and theories in an interactive multi-disciplinary learning environment. This course focuses on placing selected movements and developments of production and performance in the context of the student?s specialist discipline. There is a focus on experiencing professional art making in the community through field trips and site visits.
- Pre-requisites / Co-requisites:
- There are no classes on public holidays.
Class: 6437. This timetable is currently unavailable.
You need to attend all sessions of this class as listed below.
|From - To||Session||Day||Time||Campus (Room)|
|24 Jul 19 - 25 Sep 19||Studio||Wednesday||09:30 - 12:30||Mt Albert (006-2064)|
|16 Oct 19 - 20 Nov 19||Studio||Wednesday||09:30 - 12:30||Mt Albert (006-2064)|
- Note: This course is offered as part of Bachelor of Performing and Screen Arts (Acting for Screen and Theatre), Bachelor of Performing and Screen Arts (Production Design and Management).

domain: artistic


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Karen Bravo is Afro-Colombian Artist based in Melbourne. My vision is sharing layers of my roots in our Merch Bags. With that in mind, we were able to collaborate with Karen Bravo for this stunning masterpiece about The Goddess of the Ocean " Yemanja Yemanja, the goddess of the sea. In this beautiful masterpiece, she is holding a sea shell which is magical blessings of motherhood and fertility.
Ife is Art - By Karen Bravo


Nick Kyrgios has declared himself on track to make amends for his injury-wrecked Wimbledon last year after turning out for a surprise appearance in a low-key grasscourt event in London on Monday.
A relaxed and cheerful Kyrgios said he felt good during a doubles match at the Surbiton International Challenger Tour tournament, where he and American partner Jordan Withrow lost narrowly to Indian pair Siriam Balaji and Vishnu Vardhan.
Earlier this week, the world No.23 had pulled out of the French Open ahead of a first-round clash with former Davis Cup teammate Bernard Tomic.
He says it was the difficult but "more mature" decision needed to ensure the elbow problem in his serving arm that he's struggled with this year did not wreck his Wimbledon campaign.
He moved freely and served well during the 90-minute doubles match.
"I was serving 100 per cent, and I thought I served really well," said Kyrgios.
"I didn't put myself under any pressure and will play singles in Stuttgart next week."
Last year Kyrgios was forced to retire injured in his first-round clashes at both Queen's then Wimbledon after defying medical advice and playing at the French Open despite a hip problem.
He said this year he was given the same advice by his support staff and reluctantly listened to what they had to say to give himself the best chance to succeed on his favourite surface.
"I couldn't play the clay-court season last year properly because of a hip injury and at Queen's I slipped over and re-injured it and couldn't play Wimbledon," he said.
"I didn't have the chance to play in one of my favourite tournaments last year, but this year I feel pain-free and that is all I can ask for.
"It was massive call not to play in Paris (this year). When I saw my draw, I had the opportunity to do well.
"But I didn't want to put my grass-court season in jeopardy.
"I made a more mature decision this year.
"I had a lot of doctors and medical people telling me it was the smart move."
Kyrgios is once again travelling with his mother, who will spend the next month with him.
He appeared to be in a positive frame of mind, cracking jokes with photographers and ball kids on court and posing for selfies with school children.
"I haven't been in this head space for a while where I am looking forward to going out to training," he said.
"I think playing doubles has helped me enjoy myself again and I am going to stay here for the next few days and practise before going back playing singles again."


Posted on Tue Feb 16, 2010 12:01 PM PDT
Despite reports that Leonardo DiCaprio and Bar Refaeli got engaged over the weekend, E! Online reports that it's a false alarm. Whew!
Bar was spotted with a ring on her left hand last night at the Cinema for Peace Gala at the Berlin Film Festival, but a source close to star says the lovebirds are "definitely not engaged."
No offense Bar, but we think Leo can do WAY better than you!
SEE THE GALLERY Leo And Bar In Berlin
FIRST LOOK - Leonardo DiCaprio And Jamie Foxx In Quentin Tarantino's Django Unchained - Jun 07, 2012
Leonardo DiCaprio Rents Malibu Estate For $75K Per Month - May 29, 2012
FIRST LOOK - Leonardo DiCaprio Shows Plenty Of Swagger In The Great Gatsby Trailer - May 23, 2012
EXCLUSIVE PHOTOS - Leonardo DiCaprio Lunches With His Dad George - Jan 11, 2012
Leonardo DiCaprio Attends J. Edgar Opening Night Gala - Nov 04, 2011


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Too cute small red heart character couple (the hearts read "Forever
Yours" and "I Love You (2)") on a white, professional 4-inch cake
topper base. White ruffled lace adorns the base, and the white
heart-shaped background is adorned with red and white ruffled lace. A
red bow with pearl-like heart center is in the middle of the
heart-shaped background, and red and white organza flowers also adorn
the background. Measures roughly 8 inches high. Great for a Valentine's Day wedding or centerpiece!

domain: design


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Separate names with a comma.
Discussion in 'Raising Baby Chicks' started by wilhiteranch, Jun 27, 2011.
How do you give chickens vitamins?
Many BYC members use the supplement Poly Vi Sol (without iron), though I'm sure there are other substitutes. I believe you can put them in the water, or you can put it in a dropper and dribble a bit down the side of your chicken's beak, and the chicken will be forced to swallow it.
I use polyvisol in their water. I use 1ml per quart of water. I only put down the beak if they are sick. The vitamins saved my chick from dying with pnemounia.
You can also get vitamins at the feed store specifically for chicks. We used Save a Chick vitamins and just mixed it in with their water. If I hadn't had found those, I would have just gotten the Poly Vi Sol from the pharmacy.
This is what I use. I mix it with water and give it to my chicks for the first couple of weeks. I also give it to my older birds during extremely hot or cold weather.
A water soluble premix of vitamins and electrolytes specifically formulated as a water or feed additive; for use when animals are subject to conditions of stress. For use in cattle, horses, goats, sheep, swine, poultry. One package will make 128 gallons.
Quote:If you use Poly-Vi-Sol get it without iron...
Thank you ! I'll go to the feed store and see what i can find. Also how often do you give the vitamins?
If fed a good diet chicks (or humans for that matter) to not require vitamin supplementation.
My oldest chicks are over 3 months and I still give them vitamins. I'm going to finish this bottle and save the unopened bottle for when they are sick.
I know it's not necessary, but my chicks look really good! The vitamins has made a difference.

domain: pet


Hey guys I have an 07 V6 Fusion with almost 60k miles on it. Today when I was sitting in a drive through I noticed that my engine was making this clicking noise. I thought maybe it was the car behind me so I shut the car off and the sound stopped. Turned it back on and there it is again. Is it normal for these engines to make a clicking noise while idling?


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Be careful here. These people are quick to get all your personal details before telling you there is no work. They said they had jobs in central London so I could apply even though I live several counties away. They were very rude when I said I wanted more security, not just send private info over the internet.
This user has arrived from Qype, a European company acquired by Yelp in 2012. We have integrated the two sites to bring you one great local experience.

domain: geography


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In this section, you will understand the value of studying area maps for a project prior to the development of the flight plan.
Flight planners should acquaint themselves with the project area through two types of maps before proceeding with further steps of the design; those are U.S. Topo Quadrangle Maps and Sectional Aeronautical Charts.
U.S. Topo Quadrangles Map
The U.S. Topo Quadrangles Map, mainly a topographic map, shows the details of the contours of the land (terrain elevation). See Figure 4.1. This type of map reveals all information that a planner needs about the topography in the project area. Topography affects flight plan parameters such flight lines, spacing, and imagery spacing. Quad maps can be downloaded from the USGS. You can also review a sample of such maps for the State College area.
Sectional Aeronautical Chart
Sectional Aeronautical Charts, which are also called VFR charts (Figure 4.2), are described as “the primary navigational reference medium used by the VFR pilot community. The 1:500,000 scale Sectional Aeronautical Chart Series is designed for visual navigation of slow to medium speed aircraft. The topographic information featured consists of the relief and a judicious selection of visual checkpoints used for flight under visual flight rules. The checkpoints include populated places, drainage patterns, roads, railroads, and other distinctive landmarks. The aeronautical information on Sectional Charts includes visual and radio aids to navigation, airports, controlled airspace, restricted areas, obstructions, and related data. These charts are updated every six months, most Alaska Charts annually. To better understand these charts, review the FAA “Aeronautical Chart User Guide”. You can also watch this YouTube video on learning how to read the sectional charts:.
The topographic map and the aeronautical chart provide an overview of the area and the contents of the ground cover (both natural and man-made), restricted airspace such as airport approaches, high towers, etc.
Visualize FAA On Line Data and Charts
No less important than visualizing a sectional chart, is to utilize the online FAA sites and other services, which allow you to zoom in to your geographic location to stand on the airspace status and the allowed flights ceiling. Here are a couple of the free services available to the public:
1. The AirMap App
- Section 18-10 of Chapter 18 of Elements of Photogrammetry with Applications in GIS, 4th edition


Nissan Repair/faulty fuel guage
i have infinti J30, 2001 model. the fuel guage is bad as the pencil does not read again and the reserve light is does not go off again. my local tecnician advised me to get a spare fuel guage to replace the bad one. please how may i get a spare fuel guage that will fit my car and how much would it be. i am Uyo, Akwa Ibom State, Nigeria. thanks.
The fuel gauge assembly is located in the fuel tank.
Have a competent mechanic replace it. I do not know the prices where you are, but in the USA a job like this would typically be in the hundreds of dollars, maybe $200 or $300 depending on how much the fuel pump is.
Hope this helps -


Chicago screw posts make creating swatch books fast and easy. Create a compilation of material samples or other artistic project with covers and interior pages that swivel open with screw post binding.
Most screw posts are threaded for quick removal, which also allows for interior pages to be changed, added or removed.
To create your own swatch book with screw posts, you need:
- Your front and back exterior covers
- Your interior pages
- A screw post (consisting of a threaded post and a screw head)
- A hole punch or paper drill
- A small flathead screwdriver (that matches the width of the screw head)
Swatch Book Assembly Instructions:
- Prepare your book by stacking your pages in the correct order with exterior covers on the outside.
- Determine which corner or edge of your book is going to be the fixed, bound edge.
- Punch a circular hole in the spot where you want your book to be bound. Most standard hole punches create holes that measure 1/4 in. in diameter, which perfectly fits the 3/16 in. diameter of a standard screw post and allows for some wiggle room.
- Thread your pages over the threaded post base, with the flat base against the back exterior cover.
- Screw the head of the screw post into the threaded base to lock in the pages. Note: Some plastic screw post varieties simply "snap" shut.
Can I also build cabinets, bridges or rocket ships with screw posts?
Standard plastic or aluminum screw posts are only intended for graphic arts and paper binding purposes – not for heavy duty construction or special engineering projects.


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2 edition of Land in Utah found in the catalog.
Land in Utah
Claron E. Nelson
by Bureau of Economic and Business Research, College of Business, University of Utah in [Salt Lake City]
Written in English
|Statement||[by] Claron E. Nelson [and] Irving N. Fisher.|
|Series||Utah public lands research, Studies in Utah"s natural resources and regional development|
|Contributions||Fisher, Irving Nuttall, 1936- joint author.|
|LC Classifications||HD243.U8 N4|
|The Physical Object|
|Number of Pages||41|
|LC Control Number||61064085|
3, tract books containing official records of the land status and transactions involving surveyed public lands arranged by state and then by township and range. These books indicate who obtained the land, and include a physical description of the tract and where the land is located. The type of transaction is also recorded such as cash entry, credit entry, homesteads, patents (deeds. Young led the Mormons on their great trek westward through the wilderness some 1, miles to the Rocky Mountains—a rite of passage they saw as necessary in order to find their promised land.
Everything you need to plan your Utah hunting trips for Access district and public hunting land maps. Get the latest species season information. Buy a cheap copy of A Land Called Deseret book by Janet Dailey. Every novel in this collection is your passport to a romantic tour of the United States through time-honored favorites by America’s First Lady of romance fiction. Free shipping over $
Discover Utah land for sale. Easily find property for sale in Utah including acreage, rural property, vacant land, hunting land, recreational land, and investment property at This brings you to the rest of the Wasatch Front. In this book, the section that's roughly north of Salt Lake is designated the Northern Wasatch Front. Here you'll find historic Ogden; Logan, Utah's northernmost town of any size; the national historic site where the Central Pacific and Union Pacific railroads met in ; and four ski resorts. The mountains that offer skiing in winter also.
Scottish farm buildings survey.
William H. Johnson.
Piranesi, Rome recorded
Essentials of Electric Motors and Controls
The 2007-2012 Outlook for Fresh and Frozen Primal, Subprimal, Fabricated Cuts, and Boneless Veal Made in Slaughtering Plants in Greater China
spy who wasnt caught
Understanding the social worlds of immigrant youth
British electricity system
Its still the law.
Research in socio-cultural development
life of Krishna in Indian art
Assessment and evaluation for student centered learning
Real money, real choice
Working in a shop.
1 - 25 of listings - Browse Utah properties for sale on Lands of America. Compare properties, browse amenities and find your ideal property in Utah. Utah Land. 4, results. Sort by: Newest. Homes for You Price (High to Low) Price (Low to High) Newest Bedrooms Bathrooms Square Feet Lot Size.
LOT 12 Juniper Way, Leeds, UT Lot / Land for sale. $, 1 acre lot; 4 hours ago. CENTURY 21 EVEREST ST GEORGE. Reel Rd #20, Panguitch, UT Browse Land And Farm for farms, ranches and rural real estate for sale in Utah, including undeveloped land currently listed for sale in the Beehive State.
Recent listings in Utah of undeveloped land for sale totaled aroundacres acres of undeveloped land and a combined market value of $ million.
Cheap Land for Sale in Utah. Buy Cheap Land in Utah. Building lots for sale, raw land, acres, ranches, vacant lot. Utah mountains mountainview land lots. The Tony-winning “Book of Mormon” musical is in Utah’s Zion for the third time, bringing its own brand of raunchy, raucous, yet oddly reverential satire back to the Salt Lake City Utah Land for Sale by Owner (FSBO) Sort.
Advertise Here. This lot won't require much work to get it ready to go, the land is flat and cleared in this location. Along the south side of the property there is a paved road, and along the north side there are power lines.
With thousands Land in Utah book properties and rural land for sale in the state, this represents a combinedacres of land for sale in Utah. The average price of Utah land parcels for sale is $, The state has been ranked among the ten best states for retirement by Kiplinger.
Game species to be found on land for sale in Utah include elk, mule. Books, fiction and non-fiction, set in Utah. Not just LDS books. All Votes Four Corners: History, Land, and People of the Desert Southwest by.
Kenneth A. Brown (Goodreads Author) avg rating — 53 ratings. score:and 2 people voted. BOOK A HUNT. More () If you’re looking to go elk hunting in Colorado or Utah you have come to the right place.
We are expert Colorado elk hunters and offer bow and rifle hunting adventures. RUSTIC COMFORT. Approximat acres of private land surrounded by BLM is yours to explore while enjoying comfortable cabins, hot.
The Book of Mormon describes a "land of promise" given to Lehi and his posterity by the Lord. Many have wondered where this land of promise might be physically located in the Americas.
Historically, Latter-day Saint leaders have identified the range of North and South America as the land of promise, as well as the land of Zion. But more important than where the land of promise.
Browse 33 Grand County, Utah for sale on Lands of America. Compare properties, browse amenities and find your ideal in Grand County, Utah. Utah has a rich cultural heritage that dates back to 11, BP. Visit prehistoric rock art in Nine Mile Canyon, gaze upon pueblo homes in Cedar Mesa, or follow the Hastings Cutoff National Historic Trail across Skull Valley.
When visiting these cultural sites, please remember to respect and protect. Utah Frequently Requested MapsThe BLM manages nearly million acres of public lands in Utah, representing about 42 percent of the state. Located mostly in western and southeastern Utah, these lands are varied, ranging from rolling uplands to sprawling desert lowlands.
Utah’s public lands feature some of the most spectacular scenery in the world, from the snow-capped peaks. Based on total acres, Utah's Southwest region has the most land listings and rural property for sale in the state on LandWatch. Internal data from LandWatch records about $1 billion of rural land listings for sale in the Southwest region of Utah.
This covers s acres of land for sale. The average price of land and ranches for sale here. Searching for Utah land for sale. Browse National Land Realty listings, your source for farm, ranch, waterfront and recreational land real estate.
Utah Land Brokers & Real Estate Agents: National Land Realty - Utah Office. E N. Lehi, UT P F Land Ownership Land Ownership.
Category: Cadastre Data Type: GIS Data Layer Steward(s): SITLA, BLM, & Partners Abstract: nership feature class depicts land ownership status and areas of responsibility for the State of Utah surface lands at a scale ofMaintenance of this data layer is performed by a cooperative federal and state effort between the Bureau of Land.
Peay is Mormon and his striking claims regarding public land have a long history in Utah. Under Trump, these claims are being taken seriously.
Peay. This exhibition is the result of a collaboration between the Book Arts Program, the Utah Museum of Fine Arts, and the Rare Books Department. It coincides with two events (see below) inspired by Nancy Holt’s famous land art piece, Sun Tunnels, located in Utah’s west desert.
March 23 through June 3, Level 1, J. Willard Marriott Library. Records of the Miles City land office ( ), consisting of serial register books and land entry case files, Records of the Missoula land office (), including tract books, ; serial register books, ; and land entry case files, Records of Nebraska land.
Utah has some of the best Rocky Mountain Elk hunting in the world. Many of Utah’s elk units can produce giant bulls year in and year out.
Every few years a unit will have a stand out year, predicting this can be difficult. Although “quality” is reportedly down from levels, Utah is still a premier hunting destination for BIG bulls.
Small holding land patterns in Utah and the problem of Forest Watershed Management. [Charles S Peterson] Home. WorldCat Home About WorldCat Help. Search. Search for Library Items Search for Lists Search for Book\/a>, schema:CreativeWork\/a> ; \u00A0\u00A0\u00A0 library.
Land of the Canyons: A Photographer's Guide to Utah and Arizona, 2nd Edition Paperback – March 1, by Laurent R. Martres (Author) out of 5 stars 13 ratingsReviews: The average price of residential land and property for sale in Utah was $ million.
Browse all residential property and land for sale in Utah to find residential land and properties that suit your lifestyle needs, from existing residential homes and estates to land .


text:
Learn to Machine Quilt Class DVD
Learn the techniques and tips to develop your free-motion machine quilting skills!
In this quilting class, you will:
- Discover which threads, needles, batting and notions work best with machine quilting
- Learn how to securely start and stop stitching
- Discover how to imprint quilt motifs in your brain before taking them to the sewing machine
- Practice and learn straight-line stitching close together and far apart parallel lines, corners and crosshatching
- Learn free-motion quilting techniques stippling, swirly vines, interchanging vine, allover swirls, jester's hat, single and double echoing, and pebbles.
Learning these techniques and quilting motifs will greatly enhance and broaden your ability to finish your quilts, allowing you to add more texture, depth and beauty to your quilted creations.
Note: Annie's DVD video classes include a CD with downloadable and printable class project instructions, materials lists and diagrams. DVDs are compatible with North American DVD players, and PC and Macintosh computer systems. All Annie’s online classes and DVDs have closed captioning.
Video Length: 1 Hours 35 Minutes
How do you like this product?
Share your thoughts with the Annie's community.
January 27, 2014
I agree with the previous reviewer. I am also a 60+ yr. old beginner and love this DVD. I am really looking forward to trying the techniques and the instructor makes it all seem very possible and not as daunting as I had imagined. Thank you!!
January 27, 2014
This DVD is wonderful!! The instructor makes you feel like she is right in the room with you. Will be looking for more DVDs on her quilting techniques. I am a beginner and 60 years old so I need all the help I can get. I am hooked on this already. Thank you for making feel like this is not over my head. Deb from Mo.


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This weekend, cheap 'n' best Nepal
Kathmandu, in spite of all its political upheavals, has turned out to be the number one travel destination for Delhiites this extended weekend (a leave on Monday, followed by Gandhi Jayanti on Tuesday). Nandini R Iyer reports.india Updated: Sep 29, 2007 02:11 IST
Kathmandu, in spite of all its political upheavals, has turned out to be the number one travel destination for Delhiites this extended weekend (a leave on Monday, followed by Gandhi Jayanti on Tuesday).
Flights to the neighbouring kingdom are full between Saturday and Tuesday, as are hotel rooms.
Why Kathmandu? With budget packages costing as little as Rs 12,000 per head (that includes ticket, airport to hotel transport, accommodation and some meals), tourists are flocking to the Himalayan kingdom, say tour operators. Moreover, the flying time is just one hour and 20 minutes.
Jyoti Mayal of New Airways Travels, an umbrella organisation of travel agents in north India, said packages range from Rs 10,000 to Rs 13,000 per head for three nights. "Most have special discounts on family bookings,” she said.
"All flights to Kathmandu on Friday are already full," a Cox & Kings official told HT on Wednesday. Even Indian Airlines flights are choc-a-bloc between Friday and Tuesday; Wednesday too is tight.
It’s not just Delhiites. A spokesman for Consolidated Holiday India, which connects travel agents in small cities to tour operators in metros, said, “There’s been a crazy demand for packages to Kathmandu from smaller towns. In Ludhiana alone, 28 families separately made bookings for this weekend."
First Published: Sep 29, 2007 00:25 IST

domain: news


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It all began with drawing at a very early age. People began knowing me for my skills with the pen as I got older and with that I began opening up to more techniques, mediums and ideas that grounded my style and interests more and more. Nowadays the rule is: if I can get my hands on it, it's fair game.
Good literature, good films, good music,nature in general is vastly amazing.
My wife, my parents, my little sister, our cat Keebler and my homeland.


Thread: BobCad 80% off list
By profile I mean a profile of the part being machined.
Here's an example:-
Loco wheel with cutter selected, Op 5, Op 6 is the pockets, only one is selected but it's been told to cut all pockets drawn on the same layer.
Now the pocket isn't clean, there are some pips left as it cuts at 70% overlap by default [ can be changed in options but 70% works for most things ]
Double click Op5 and you get the same dialog box come up as when you set it.
In this box we see the overlap which I will change to 65% also you get a choice of how to contour, which way to go regardless of how it was drawn, no stupid arrows. Choice of travelling at clearplane or feed plane, that machine all contours I mentioned and ignore cup depth makes it do the last cut at full depth less any excess put on for the last cleanup pass.
Click OK and see the result.
Job done, now up to this point no code has been written at all, you can play about to your hearts content and ONLY when you are happy with the screen shots do you press Post code and select the post processor.
The code should be perfect and the only editing I do is on the machine and play with the speeds and feeds depending on how it's cutting.
The first time I ever see the code is when it's loaded into Mach or whatever.
I never have to edit the code, if I want any changes I change the operation, watch the preview and post a complete new code.
.John S -
Hope you spelt my name right, I didn't
Loads of good video's on the site and also the US site, I think the US site is better.John S -
Sorry missed that connection, yes I know blind and thick but someone has to carry the cross.
.John S -
I have gotten mixed levels of support from BobCAD and I use V21. Have no real problems with it remembering tools in the tool tray. Have no real problem with the offsets. Only Problem is in the CAM side it keeps putting M6 and M4 which with a manual set up milling bit there is no need for them so at the moment I just gone in and edit that part as to lazy to go into the post processor atm to make the changes. Have had problems with them and there are things they could do better. But than again if you bargian a bit you can get some very good deals from them. SolidWorks is a great program IF you got £1K+ sitting around for the investment. Now if some one knows a way of getting those programs without paying for every part plus tech support please tell me. I remember the day when you bought a product and a certain level of support was expected and included within the product.
Will see as the road goes though have had some very good cutting come out of code set up by BobCAD/CAM and also been doing some larger project work in it as well.
I as you know a good part of my milling is completely through the wood so I use the finish spiral pocket with a proper offset and everything goes just fine. For the milling of pockets on harmonica combs I still find it easier to generate code from the geometry as doing it the pocketing method generates to much code and eats up time like mad. I run it at a 25° to 65° angle and a small step over and two passes with it running at 250mm/min with a 2.5mm EM multi tooth bit. Will eat wood or acrylic like candy and leaves a very nice edge (very little sanding/filing needed).
On the subject of bits have you looked a Sorotec.de they have a wonderful selection at really nice prices. I have also found them and one other German firm to have reasonable prices for Kress collets.
By Mad Professor in forum CAD & CAM SoftwareReplies: 71Last Post: 01-02-2016, 05:46 AM
By suesi34e in forum BobCAD-CAMReplies: 2Last Post: 07-12-2013, 03:13 PM
By Robin Hewitt in forum General DiscussionReplies: 4Last Post: 27-08-2011, 12:40 PM
By m.marino in forum BobCAD-CAMReplies: 0Last Post: 15-01-2009, 07:58 AM


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For Knoxville boxer Joell Godfrey, facing reality-show cameras is tougher than punching another guy's lights out.
Godfrey, who works the grill at Aubrey's off Middlebrook, says he had a hard time adjusting to cameras chronicling his every step on "The Contender" (starting 10 tonight on Versus). He's among the 16 athletes vying for the show's title this season.
"I was basically (suffering from) stage fright when I fought," the 28-year-old, 195-pound athlete says of his experience on the show.
"I fought well in my own weight (division), but I was also (dealing with) stage fright with the cameras constantly being on (me) 24/7. We had to get used to the TV part of it because this wasn't a regular fight."
Not much intimidates Godfrey, who has a 9-0 professional record in the cruiserweight division.
Exposure garnered by being on "The Contender" is invaluable to a boxer's career, raising the profile of the athlete and opening up opportunities for bigger and better matches.
"This (show) will put us out there in the atmosphere," Godfrey says. "The more I promote myself ... the more (chances) I have to make it big. At the end of the day. I'm just a regular guy who's having fun doing it."
Godfrey says doing the show was an adjustment for him.
Production took him out of the country for the first time. "The Contender" was shot this past September in Singapore.
Godfrey, who grew up in Winston-Salem, N.C., had never been out of the country before.
He admits he wasn't entirely pleased by how he performed on the show.
"I won't lie about it," he says. "I knew I could do more. The (athletes) who were there understand the pressure with the cameras being there."
n Eat up. Food Network is cooking up possum - Gatlinburg style. Yummy, right?
Chef Andrew Zimmern and his gang from "Bizarre Foods" shot a segment a month ago at a Sevier County cabin party, complete with a bluegrass band. The menu included grilled raccoon, baked possum and bear stew - you know, the kind of stuff mom used to cook.
The episode is scheduled to air in March.
Also, Food Network personality Mark Summers from "Unwrapped" was at Baskins Square in October shooting a segment at the funnel cake place for an episode to air in the spring.
Terry Morrow may be reached at email@example.com or 865-342-6445. His blog can be found at blogs.knoxnews.com/knx/telebuddy/. He contributes to "Live @ Five @ Four" on WBIR, Channel 10, and "The Marc & Kim & Frank Show" on WWST-FM, 102.1.


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Subject Areas on Research
- A neonatal swine model for peanut allergy.
- Impaired degranulation but enhanced cytokine production after Fc epsilonRI stimulation of diacylglycerol kinase zeta-deficient mast cells.
- In vivo studies in C4-deficient guinea pigs.
- Purine derivatives as potent Bruton's tyrosine kinase (BTK) inhibitors for autoimmune diseases.
- The development of homologous skin-sensitizing antibodies in experimental thyroiditis.
- The relationship between antibody affinity and the efficiency of complement fixation.

domain: biology


Please note this is Pre-Order.
ETA: End of Dec 2021
[PO DEC] OD2848 TC Aluminium Rear Up Upper Bracket (For Galm / Red)
Wide offset mount on the rear upper arm!
Greatly improved drift controllability and traction performance! !!
Rear upper arm bracket produced by OD support driver TAKE-C. By using this bracket, it can be offset mounted to the outside in 3 steps of 7, 9, 11 mm with respect to the standard position. The load applied to the tires is instantly controlled by quick load transfer and roll, and the machine is surely led to the acceleration system. In addition, the compatibility with the TC low mount suspension mount is also the best, and it is possible to optimize the suspension geometry by widening both the lower and upper. It can be attached to both normal resin and optional aluminum upper arm cloaks. Available in three colors: purple, red, and black.


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Where sun-bleached driftwood lies helter-skelter on long stretches of silvery sand. Where gnarly trees cling to windswept bluffs and beach grasses hold fast against king tides and raging storms. Painting beaches offers endless inspiration.
I enjoy the loose spontaneous feel of watercolours. The qualities of wet paint on wet paper. The flowing and blending into provocative shapes. When a slip-up often creates a suggestive shadow. A simple brushstroke. The rich texture of watercolour paper.
I like to convey optimistic moods like a sunshiny day with a clear blue sky and shimmering water on the horizon. I also like to create personalities such as herons decorated in uniform. Harlequin ducks on parade. Seagulls with attitude.
I like to tell a story, trigger a memory or simply give you a good feeling with my art. Although watercolours is challenging because you can’t cover over an error, I love when colours and paper interact. I like to allow for chance and let the chemistry create alchemy.
Creativity does exist, but it must find you working – Pablo Picasso
For me, art is not a passion
But a compulsion.
It’s not only what I see
But a reflection of me.
When the sun makes a shadow
When the earth grows a tree
I can too. This empowers me.
It’s not just what I see
But a reflection of me

domain: hobby


text:
- Best Selling Themes
- App Themes
- Business Themes
- Popular Themes
- Email Marketing
- Free Themes
For Stationery Shop Owners, Stationery Manufacturing Companies And Various Others From The Same Field Of Business.
File jackets are as important as any other covers of an item, these file jackets keeps the entity secured and look very professional, the sellers of such jackets that want an online platform and want to expand their businesses can do so through a theme.
And this theme is termed as the File Jackets WordPress Theme that enables the user to display all pertinent file jackets that are selled by them.
The respective template can be used by stationery shop owners, stationery manufacturing companies and various other from the same field of business.
The skin has some great features that will help the user to display all the file jackets amazingly, all the important entities that the user feel that should be exhibited on the theme.
The template has a WooCommerce section where all the products that are related to the stationery products like file jackets and other items, the customers can add them to the cart and then do the final payment through integrated PayPal gateway system.


text:
A preface and final plea. Two days from now, Saturday 10/15, is the Krempels King of the Road Challenge. Presumably by now if you are going to ride, you have already signed up so it’s just a matter of putting air in your tires and then downing some Dunkin Donuts (one of our exemplary supporters) on site before setting off on the ride. Alternatively, if you would like to participate without straddling a bicycle here is my fund raising website. 100% of your donation goes to the Krempels Center bettering the often challenging lives of those with brain injury. We sincerely thank you… and now back to the show.
I woke up yesterday with a hankerin’ for a bagel.
Not just any bagel, however, I wanted a bagel from Scratch Baking Co. Strangely I’m not a bagel person – heck, I think the last time I had a bagel was sometime in May and in general I probably have only three bagels a year. It’s not about quantity though, it’s entirely about quality and Scratch bagels offer a lightly crisp and satisfying exterior bite surrounding a pillowy soft and almost nutty interior thereby combining to create the most delicious bagel this planet has ever seen. In a word: Uuu-flippin’-maaazing. The only issue being that Scratch Baking Co is up in South Portland, Maine and I’m currently in southern New Hampshire. A quick Googlemapping indicates that this is about sixty-plus miles door to door which means only one thing: it’s time for a bike ride.
Conveniently I went to bed the previous night with the same hankerin’ for that same Scratch bagel, because yesterday’s afternoon forecast was less than favorable and more than dry. Therefore I had to hit the road early enough to bang out my To-Do list.
October 12 To-Do List:
-Ride one-hundred mighty kilometers to South Portland, ME
-Stop briefly for a bagel
-Participate in friendly conversation
-Pedal one-hundred more kilometers home
-Don’t get rained on
This craving offered the fringe benefit of a beautiful fall tour of New England. Amid cool overcast temperatures typical to this geographic slice of the world in the fall, I meandered up along the Maine coast weaving in and out of incredibly foliaged forests, zoomed by stone walls hundreds of years old, fought brisk winds coming off the Atlantic Ocean, screamed along dirt bike paths, pedaled through tourist towns, farm stands, approximately seven-thousand pumpkins, muddy tidal marshes, and rode by only a half dozen cyclists. Two French Canadians on holiday tried to half wheel me for a brief while when I was 110 miles into my 125 mile jaunt, we casually chatted a bit before I dropped them.
And now here is my photo journal. Oh, and before you give me crap for it, yes I had my camera-phone set on those instant photo editors to look more dramatic. Needless to say, the ride was still very dramatic.
Uh-oh, don’t get lost. This photo is near downtown Kennebunkport. I gave George Bush(es) a buzz on the twitter if they wanted to ride. They didn’t reply, sadly.
Arrival at last! Actually I was flying while en route up north, cruising into town well over 20mph only to learn that I was riding into a deceptive headwind. The ride home was even more zippity.
Bob ebulliently greeted me with the outstanding news that my mid-day arrival still offered bagels, since these doughy treats frequently sell out. I snuck inside and talked to Sonja for a while as well while sipping pipping hot coffee. Talking bikes, bike racing, baked goods, coffee, and life – friends, life is good.
A further smattering of what’s for sale.
Cheers Bob! Coffee and a bag of bagels for my hundo’ kilometer ride home. Also please note the tub of Fluff to the left.
All that for a bagel. Was it worth it? Absolutely.


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Moving into the second position group of our 2019 recap, the running backs for the Green Bay Packers showed out over the course of this past season. Led by Aaron Jones, who has more than made a name for himself in the NFL, and supported by Jamaal Williams, Tyler Ervin, and fullback Dan Vitale, this group was what helped keep the team in each and every one of its games.
Jones was the clear cut workhorse, as he should be, and he put together his best season so far in his young career. The UTEP draftee has been a superb find in the middle round of the NFL draft, showing yet again that the entire Green Bay organization understands the importance of drafting and developing talent.
2019 stats – 16 games, 1,084 rushing yards, 474 receiving yards, 19 total touchdowns, 3 fumbles (2 lost)
Having added over 500 more yards and 10 more touchdowns to his stat line in 2019 compared to ‘18, Jones was absolutely phenomenal for the Packers and easily was the best offensive player that they had this season. By taking a share of the load off of Aaron Rodgers, Jones’ efficiency improved (it seemed) as the weeks went on, mixing in a healthy dosage of passing targets along with rushing carries.
Averaging 4.6 yards per carry and 9.7 yards per catch are very healthy averages for a starting RB that opposing defenses will be keying in on. In the team’s Week 8 contest against the Chiefs in Kansas City, Jones tore that defense apart to the tune of 67 rushing yards (13 carries) and 159 receiving yards (7 catches), scoring two receiving TDs in the team’s victory.
After that KC game, Matt LaFleur ended up going away from focusing on Jones in the passing game as much as he had been, which led to the team becoming a bit more one-dimensional. The final seven games of the season after their bout with KC saw Jones only catch 15 more balls, with six of those coming Week 14 against Washington.
Rushing wise, he was able to have so much success due to the health of the offensive line, as David Bakhtiari and Bryan Bulaga held down the tackle spots practically all year, Corey Linsley was their rock at center, and both Billy Turner and rookie Elgton Jenkins were unmovable at guard.
Moving forward, teams will be keying in more on Jones in the GB offense, so LaFleur will need to scheme him into the offense more and in better ways, potentially utilizing motion and sweep concepts to draw the defenses to multiple parts of the field.
Jamaal Williams, Tyler Ervin, Dan Vitale
In the main backup role, BYU product Jamaal Williams missed two games in his third season due to injury, yet still was right in line with his career averages. Rushing for 460 yards and one TD on 107 attempts, and catching 39 balls for 253 and five scores represent a solid season as the backup to Jones.
Williams is capable of being a starter if called upon for injury reasons, which makes him a valuable commodity to have on this team. A huge part of his usability comes with him never having fumbled the ball once across his three-year career in the NFL, which shows that he needs to be rewarded for his ball security.
Tyler Ervin was signed off the street and suited up for four games with GB, bringing a speed threat to their offensive schemes. Commonly utilized as a jet sweep/motion man, Ervin did not have a huge role in the offense, yet would be a cheap, smart option to bring back next season.
His speed was best utilized in the return facet of the game, fielding six kicks for 160 yards (long of 45) and 11 punts for 106 yards (long of 18). While those numbers may not jump off the page necessarily, the fact that in his first game fielding punts, Ervin set back-to-back team longs of punt returns on consecutive attempts, and all were seemingly under 15 yards per return.
The impact that Ervin had in the return game should help boost his chances at returning to this team next year, especially with how he could be thrown into the offensive game calls for a full season.
Dan Vitale represents a dying breed in the NFL, as fullbacks are not getting the due that they deserve. Having just completed his second year with the Packers, Vitale’s role in LaFleur’s offense seems to be very solid, as he understands the importance of not only having a stout blocking option to free up zone runs but also how being able to stretch the field with another receiving option helps open up the offense.
Having suited up in 15 games, Vitale’s presence was felt more in the receiving game than anything, as he fell three yards short of 100 yards on the season in ‘19. With seven receptions and a long of 27, Vitale’s role, while not always noted on the stat sheet, is something that should not go unnoticed.
Rookie sixth-rounder Dexter Williams from Notre Dame did next to nothing for the team this year, and he should not be looked at as a solid contributor moving forward. The 2020 draft boasts solid running back prospects throughout all rounds, and the team would be smart to try and pick one of them up.
Ervin is the lone free-agent of this group, but Jones is slated to become a free agent next offseason, which presents a hurdle for the team moving forward. If they are unsure that they will be able to resign him, using a 3rd – 5th round pick on a back, like a Clyde Edwards-Helaire from LSU or Cam Akers from FSU, would be a smart move.
Jones is a free agent in the same offseason as David Bakhtiari, Kenny Clark, and Kevin King, among others, but he may be the riskiest player to sign due to his workload. If he strings together another solid season in 2020, his price tag will continue to climb.
Mike Johrendt has been an avid fan of the Packers ever since he can remember. He is now a writer at PackersTalk and you can follow him on Twitter at @MJohrendt23


text: This chapter shows that four of the six southern urban areas pulled out of the urban crisis and qualify as examples of urban rebirth. This brief examination of the southern urban areas shows that four of the six did well in the 1990s-well enough to be classified as places of urban rebirth. The twelve urban areas of the Sunbelt included in this study produced a rather diverse record in the 1990s. The central cities of Dallas-Fort Worth, Birmingham, San Diego, and Phoenix experienced some difficulties. Dallas-Fort Worth and Birmingham did not really turn urban crisis into urban rebirth in the 1990s. When people last visited the Sunbelt metropolitan areas in and, it was concluded that three had not really experienced the urban crisis in the manner that would be recognized in the Northeast.


(TMU) – Migaloo, who is arguably the most famous humpback whale in the world, was spotted Tuesday, June 15, making his way north along the east coast of Australia on his annual migration.
About 35,000 humpback whales, which include Migaloo, make the grueling journey from Antarctica to the waters off of Queensland each year.
The White Whale Research Centre and Great Barrier Reef Legacy dedicated a Twitter account for Migaloo to let everyone know about his movements. The first sighting of the season was on Tuesday.
The Twitter account said: “A white whale possibly Migaloo has been sighted along the NSW South Coast heading north. Estimated to cruise past Sydney anytime soon and Cape Byron anytime from Wednesday this week.”
First spotted in 1991 as a juvenile, Migaloo has gained enthusiastic support from followers who love to see and capture him on camera and video. The first photograph taken of him was from over 5 km away and through a telescope. The blurry result made it impossible to determine if he was in fact all white.
Pacific Whale.Org wrote on their blog:
‘’In 1993 Pacific Whale Foundation researchers encountered this amazing white whale in Hervey Bay, Queensland. During this encounter we were able confirm the whale was all white and in 1998, we recorded the whale singing, a trait distinct to male humpback whales.’’
This was confirmed by scientists at Southern Cross University through Genetic testing in 2004. Migaloo has several physical traits that scientists can use to confirm his identity. They are able to confirm it is him with markers such as the dorsal fin on his back, which is slightly hooked, and his tail flukes that have a distinctive shape with spiked edges.
The blog continued: ‘’After sharing our remarkable discovery with the public, there was an outcry to ‘name the whale’. It was decided that the naming of the whale should be done by the elders of the local aboriginal collective in Hervey Bay. Ultimately they named this animal “Migaloo” or “white fella”. The elders explained their connection to all white or albino animals and that they appear on earth to be respected and revered; that their unique color demonstrates the need to respect all forms of life even if they appear different than ‘normal’.’’
Twenty years later, another all-white humpback calf was discovered, and over the years, there has been sightings of white orcas, and a bottlenose dolphin with albinism. Migaloo is indeed a very rare humpback whale.
Adjunct fellow at Southern Cross University, and the founding director of The Oceania Project, Dr Wally Franklin, said Migaloo is now into his 30s and will hopefully live as long as 100 years.
“He is now well and truly fully grown and fully mature. He’s mature socially and physically,” Dr Franklin said about Migaloo’s migratory habits last year.
“It doesn’t appear that he has had any issues with predators and he has an expectation to living as long as 100 years, which is the generally-believed life expectancy.
“Reports of his sightings have been available for just about every year of his life and so he has been very useful in cataloging whale movements. Those sightings are very valuable in confirming migratory timing.”
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Everyone at The White Whale Research Centre is jumping for joy! After carefully analysing the photos of a mysterious ‘white whale’ spotted very early in the season off of Port Douglas, it appears to actually be the big guy himself – #migaloo!! Photos of migaloo’s tail fluke were taken by @wavelengthreefcruises on Wednesday, which were able to be compared to those taken of migaloo previous years. It’s hard to believe, since this time in 2015 he was near New Zealand! To be so far north this time of year is both strange and very interesting. Thanks to crew onboard Silversonic for the photos taken on Friday of migaloo breaching #whitewhale #humpbackwhale #humpback #portdouglasdaintree #exploretnq #gbrmarinepark #thisisqueensland
While all humpback whales are protected under Australian Federal law, Migaloo and other humpback whales that are more than 90% white are “special management marine mammals” and have extra protection: boats and vessels cannot approach within 500 meters and aircraft cannot approach within 610 meters.
These laws were put into place because Migaloo’s fans act irresponsibly in their excitement to see him and he was struck by a boat in 2003 which resulted in him getting scarred on his back. According to Queensland’s laws, tour operator’s vessels are not allowed within 500 meters of the whale when he finally gets to Australia. Vessels can be fined up to AU $16,500 (US $11,298) if they break the rules.
Migaloo wasn’t initially considered albino because his eyes are brown and not the typical red or pink associated with albinism, and was called ’all-white’, or ‘hypo-pigmented’. However, in 2011, researchers at the Australian Marine Mammal Centre studied his DNA and found a genetic variation leading to albinism which confirmed that Migaloo is in fact a true albino.
This year has unfortunately not been a favorable one for international travel, but those who reside on Australia’s east coast will be keeping a lookout to spot the famous whale. For the rest of us, there’s always hope for a trip to the Sunshine Coast next year.
Dolphin Swims Through Louisiana Neighborhood in Aftermath of Hurricane Ida
A Louisiana family was shocked to find a dolphin swimming through their neighborhood in the aftermath of Hurricane Ida.
Amanda Huling and her family were assessing the damage to their neighborhood in Slidell, Louisiana, when they noticed the dolphin swimming through the inundated suburban landscape.
In video shot by Huling, the marine mammal’s dorsal fin can be seen emerging from the water.
“The dolphin was still there as of last night but I am in contact with an organization who is going to be rescuing it within the next few days if it is still there,” Huling told FOX 35.
Ida slammed into the coast of Louisiana this past weekend. The Category 4 hurricane ravaged the power grid of the region, plunging residents of New Orleans and upwards of 1 million homes and businesses in Louisiana and Mississippi into the dark for an indefinite period of time.
Officials have warned that the damage has been so extensive that it could take weeks to repair the power grid, reports Associated Press.
Also in Slidell, a 71-year-old man was attacked by an alligator over the weekend while he was in his flooded shed. The man went missing and is assumed dead, reports WDSU.
Internet users began growing weary last year about the steady stream of stories belonging to a “nature is healing” genre, as people stayed indoors and stories emerged about animals taking back their environs be it in the sea or in our suburbs.
However, these latest events are the surreal realities of a world in which extreme weather events are fast becoming the new normal – disrupting our lives in sometimes predictable, and occasionally shocking and surreal, ways.
Mom in LA Suburbs Fights Off Mountain Lion With Bare Hands, Rescues 5-Year-Old Son
A mother in Southern California is being hailed as a hero after rescuing her five-year-old son from an attacking mountain lion.
The little boy was playing outside his home in Calabasas, a city lying west of Los Angeles in the Santa Monica Mountains, when the large cat pounced on him.
The 65-pound (30 kg) mountain lion dragged the boy about 45 yards across the front lawn before the mother acted fast, running out and striking the creature with her bare hands and forcing it to free her son.
“The true hero of this story is his mom because she absolutely saved her son’s life,” California Department of Fish and Wildlife spokesman Captain Patrick Foy told Associated Press on Saturday.
“She ran out of the house and started punching and striking the mountain lion with her bare hands and got him off her son,” Foy added.
The boy sustained significant injuries to his head, neck and upper torso, but is now in stable condition at a hospital in Los Angeles, according to authorities.
The mountain lion was later located and killed by an officer with the California Department of Fish and Wildlife, who found the big cat crouching in the bushes with its “ears back and hissing” at the officer shortly after he arrived at the property.
“Due to its behavior and proximity to the attack, the warden believed it was likely the attacking lion and to protect public safety shot and killed it on sight,” the wildlife department noted in its statement.
The mountain lion attack is the first such attack on a human in Los Angeles County since 1995, according to Fish and Wildlife.
The Santa Monica Mountains is a biodiverse region teeming with wildlife such as large raptors, mountain lions, bears, coyote, deer, lizards, and snakes. However, their numbers have rapidly faded in recent years, causing local wildlife authorities to find new ways to manage the region’s endemic species.
Blue Whales Return to Spain’s Coast After Disappearing for 40 Years
Blue whales have been returning to the Atlantic coast of Spain after an absence of over 40 years in the region, when whaling industries drove the species to the brink of extinction.
Blue whales, which are the world’s largest mammals, had long disappeared from the region until the recent sightings.
The first was spotted off the coast of Galicia near Ons Island by marine biologist Bruno Díaz, who heads the Bottlenose Dolphin Research.
Another one of the majestic creatures was spotted the following year in 2018 and yet another in 2019. In 2020, two whales again made their return to the area.
It remains unclear as of yet as to why the creatures have returned to the area, but controls on local whaling industries are believed to play a role.
“I believe the moratorium on whaling has been a key factor,” Díaz remarked, according to the Guardian. “In the 1970s, just before the ban was introduced, an entire generation of blue whales disappeared. Now, more than 40 years later, we’re seeing the return of the descendants of the few that survived.”
Whaling had been a traditional industry in Galicia for hundreds of years before Spain finally acted to ban whaling in 1986, long after the blue whale’s presence in the region had faded away.
Some fear that the return of the massive sea mammals is a sign of global warming.
“I’m pessimistic because there’s a high possibility that climate change is having a major impact on the blue whale’s habitat,” said marine biologist Alfredo López in comments to La Voz de Galicia.
“Firstly, because they never venture south of the equator, and if global warming pushes this line north, their habitat will be reduced,” he continued “And secondly, if it means the food they normally eat is disappearing, then what we’re seeing is dramatic and not something to celebrate.”
Díaz said that while the data certainly supports this theory, it is too early to determine climate as the precise cause.
“It is true that the data we have points to this trend [climate change] but it is not enough yet,” he told Público news.
Another possibility is that the ancestral memory of the old creatures or even a longing for their home may offer an explanation, according to Díaz.
“In recent years it’s been discovered that the blue whale’s migration is driven by memory, not by environmental conditions,” he said. “This year there hasn’t been a notable increase in plankton, but here they are. Experiences are retained in the collective memory and drive the species to return.”
In recent years, researchers have found that migratory patterns are also driven by the cultural knowledge existing in many groups of species.
Researchers believe this type of folk memory, or cultural knowledge, exists in many species and is key to their survival.
A typical blue whale is 20-24 metres long and weighs 120 tonnes – equivalent to 16 elephants – but specimens of up to 30 metres and 170 tonnes have been found.


text: Adult New Patient Form Name First Last Date of Birth Date of Appointment What Provider are you seeing?Dr. Mary ArenbergDr. George SchroederBarbara J. Lukas, RN, FNP-CEmail Past Medical HistoryPlease list year if possible.Any childhood illnesses:Past hospitalizations or surgeries:Previous Medical Problems:MedicationsCurrent medications (please list both prescription and non-prescription):Medication allergies and type of reaction:Do you have a history of Latex sensitivity or allergy?YesNoDo you or any family member have problems with anesthesia?YesNoDo you or any family member have bleeding problems?YesNoPersonal HistoryMarital StatusSelect oneSingleMarriedDivorcedWidowedSeperatedYour occupation:Last year of school completed:Select one89101112GED or equivalentAssociate Degree or College CertificateBachelor DegreeMaster DegreeDoctorate Degree or PhDDo you use tobacco?YesNoWhat age did you start?How many packs per day?Select one12345Do you use chewing tobacco?YesNoHow many days per week do you drink alcohol?How many drinks per day?How often in the past year have you had 5 or more drinks in a day?Other drug use? If yes, please explain:Family HistoryPlease list any illness in your family members such as heart disease, stroke, diabetes, cancer, high blood pressure, high cholesterol, lung disease, liver or kidney disease, depression or suicide.FatherMotherBrother(s)Sister(s)Paternal GrandfatherPaternal GrandmotherMaternal GrandfatherMaternal GrandmotherPlease list your children and any health problems they have:Please check any problems listed below that you have had in the last year:Please select all that apply Fever, chills, night sweats, weight loss or gain Headaches, head injuries, concussion Eye problems, do you wear contacts or glasses? Do you have any loose or capped teeth? Dentures? Cold or allergy symptoms, nose bleeds Ear problems, hearing loss, ringing, ear pain Thyroid problems or x-ray treatment to neck or chest Breast masses, breast discharge, breast pain Breathing problems, shortness of breath, asthma, bronchitis, pneumonia, emphysema High blood pressure, rheumatic fever, chest pain, palpitations or skipped beats, heart murmur Heartburn, ulcers, gallstones, constipation, diarrhea, bloody or black bowel movements, abdominal pain Kidney or bladder infection, leaking urine, pain with urination, kidney stones Muscle pain, joint pain or swelling, broken bones, dislocations, muscle weakness Seizure, loss of coordination, tremors, speech problems, memory loss, numbness, tingling Rash, mole change, skin infections, hair loss Abnormal bleeding from any site, clotting problems, bruising easily Depression, poor sleeping, appetite problems, panic attacks, suicidal thoughts or attempts Concerns about sexuality or sexual function? Have you ever had any blood transfusions?YesNoFemales age 16 – 55: what was the date of your last menstrual period? Any additional concerns you would like to address today?

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