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The FDA is considering letting pharmaceutical companies give information to doctors and insurance companies on unproven uses of prescription drugs.
This practice, usually referred to as “off-label promotion or marketing,” has been prohibited since 1962, when Congress passed a law requiring drug companies to establish, through rigorous testing and clinical trials, a drug’s safety and effectiveness for each intended use.
The FDA held a public hearing on off-label promotion on November 9 and 10, 2016. Some 50 people testified, including drug company representatives, academics, insurance company executives, doctors, public health experts and consumer advocates.
Occurring the day after the election, the mood was somber amid Donald Trump’s surprise win. Because almost all the speakers read from prepared statements, few addressed the question that hung over the meeting: What now, under Trump, for the FDA and drug regulation?
Trump’s transition website lists FDA reform as a healthcare priority, but there are no details. He campaigned on an anti-regulation platform. In recent days, media outlets have reported that FDA leadership would be replaced. The thinking among many at the hearing was that a Trump administration would look favorably on loosening rules for drug companies.
Will There Be an Easing of Regulations?
That’s certainly the drift of things legally, which is what prompted the hearing. In 2014 and 2015, the U.S. Supreme Court, in 2 decisions, strengthened First Amendment protection for companies. That is, the Court extended their “free speech” rights, equating those rights to those of citizens’ in a way that had not been done before.
The pharmaceutical industry has interpreted the decision as giving them more leeway to communicate to doctors, hospitals and insurers more openly about their products. Indeed, the industry has won several court cases that have weakened the FDA’s authority to regulate off-label marketing.
In 2 cases, courts found that drug company off-label marketing materials for off-label uses were “truthful and non-misleading.” And in March, the FDA settled with one company, Amarin Pharmaceuticals, which had sued the FDA to gain the right to push its fish-oil drug Vascepa for unapproved uses. The company got what it wanted in the settlement. As part of the deal, it dropped its First Amendment lawsuit.
That settlement was widely seen as setting a precedent that could open the gates for similar requests from other companies, even though the larger legal issue of whether the FDA’s restrictions on off-label marketing are unconstitutional remains unresolved.
Predictably, drug and biotech company executives testified in support of more FDA flexibility on off-label promotion. But most company-affiliated speakers acknowledged the risks involved in opening the gates too widely or too rapidly.
Michael Labson, a lawyer who testified on behalf of the Pharmaceutical Research and Manufacturers of America (PhRMA), said the FDA should establish “safe harbors” for communicating certain types of information outside a drug’s approved labeling with doctors and payers.
But Labson also urged the FDA to adopt rules that would allow drug companies to use “real world evidence” — such as from studies of doctors’ results using a drug off-label — on “medically accepted unapproved uses” to promote products.
The Opposing View
FDA Deputy Commissioner Rachel Sherman suggested that was overreaching and consumer advocacy groups were adamantly opposed. Sherman asked: “What is a ‘medically accepted unapproved use’ that should be communicated versus one that might not be?”
Sidney Wolfe, a doctor and founder of Public Citizen’s Health Research Group, as well as a long-time FDA critic, was assertive: “The FDA would be reckless to weaken rules and allow the pharmaceutical and medical device industry to promote products… not proven to be safe and effective,” Wolfe said. “Opening the door to the promotion of potentially dangerous products undermines the entire FDA approval process. The FDA needs to slam this door shut.”
Wolfe cited research indicating that 80% of off-label prescription drug use lacks any or sufficient evidence of effectiveness, and is associated with a more than 50% increase in side effects compared to on-label uses.
Doris Peter, testifying on behalf of Consumer Reports and its prescription drug education initiative Consumer Reports Best Buy Drugs, also spoke in opposition. She said findings from a recent survey of 1,000 consumers indicate that “Americans do not want the FDA to allow the pharmaceutical industry to promote off-label uses of medications….The FDA will abandon its mission if it allows off-label promotion,” Peter testified.
The Consumer Reports survey found that 78% of respondents said it was either extremely or very important to them that the FDA fully vet the safety and effectiveness of medications for any specific use. And 84% opposed advertising of medicines for unapproved uses.
Somewhere between 12% and 20% of all prescriptions are for off-label uses. Doctors are permitted to prescribe any approved drug off-label because there’s no law or regulation prohibiting it.
The reasons for that are complex, but basically doctors’ trade organizations (like the American Medical Association) didn’t want the FDA — or anyone — to be able to dictate the practice of medicine. Congress went along with that. Regulate the approval of drugs, yes. Tell doctors what to do, no.
The core problem with opening the gates to drug company off-label promotion — as opposed to physician prescribing — is that companies would have even more financial incentive to do it. And that incentive is already powerful, as I pointed out in a recent MedShadow blog.
Two numbers tell the story. Over the past 25 years, the federal government has collected around $15 billion in civil and criminal fines from pharmaceutical companies for off-label promotion. But experts estimate that sales of the drugs involved in those cases yielded pre-tax profits that are at least 10 times that amount — $150 billion.
Doctors and research agree that some off-label uses are warranted. Cancer drugs are routinely prescribed off-label, for example, with acceptance. But bear in mind, as mentioned above, that the vast majority of off-label use is not well grounded in science or backed by strong evidence.
In addition, it’s usually much riskier because off-label uses are less studied. In a study published in January, the rate of side effects was 54% higher for off-label uses than on-label uses.
Most doctors know when they are prescribing off-label, but they don’t always tell patients. Neither do pharmacists. So, you have to ask, and always should with every new prescription, especially if the drug is being prescribed in an inherently risky or high-stakes situation, such as cancer treatment.
Make it routine practice as well to check every drug you take online. The approved indications are easy to find. Try the DailyMed website run by the National Institutes of Health. Search by drug, then click Indications & Usage.
What takes more digging is finding out if an off-label use is widely accepted and backed by good evidence. Web sites like drugs.com and WebMD often don’t have information about off-label use. You have to Google it. And, of course, circle back to your doctor if you don’t find the information you need.
If you are prescribed an expensive drug off-label, you are likely to hear about it from your pharmacist or health insurer. It may not be covered. That’s another reason to be proactive in getting the information up-front from your doctor.


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Barrie E. Sands, DVM
Issue: Volume 68 Fall 2022
Online Publication Date: 6 October 2022
Research over the last 30 years has begun to explore the intrinsic relationship between biology and quantum mechanics, leading to the new science of quantum biology. The convergence of these 2 seemingly disparate disciplines has revolutionized current thought on biophysiology and overall health and wellness. Important concepts covered in this review are the sensory and intuitive intelligence of the heart, the phenomenon of coherence, heart rate variability (HRV) and the creation of heart rhythms, the dynamic role of the autonomic nervous system (ANS), and the bidirectional communication network between the heart and the brain. Neurocardiology and psychoneurophysiology come into play, as well as electromagnetic fields (EMFs), biofield physiology, and quantum mechanics.
This paper provides an overview of the heart as a physiological and sensory organ at the seat of innate intuitive intelligence. The energetic nature of the heart co-creates the ability to build resilience, and establishing emotional self-regulation is the basis for achieving systems-wide coherence and optimal states of wellbeing for people and those that surround them, both human and animal.

domain: medical


text:
Confessions of a Book Worm
I adore books. I am often at my happiest reading, researching, studying, pondering; or curled up escaping from my own world for a while. Study and rest through books are both great gifts, and whilst I may need to tweak the emphasis of one over the other from time to time, there is nothing wrong with loving the rustle of paper.
However, since Lent is a time of confession and simplification: I realise I am guilty of a kind of spiritual flirtation.
I frequently fall into the habit of scanning and hunting through paragraphs, chasing a meaning I can clutch to myself. I can have times where I race through my reading pile as a consumer, quick to come to a critical summation of an author’s central point without properly reading the whole, or dismissing a work as interesting in an intellectual sense but not pertinent to me as Wisdom that I need in my life right now.
The same impulse drives me to double up on my spiritual practices: Lectio Divina with the Psalms, followed by a thought for the day from a recognised ‘heavyweight’ author, followed by reading a couple of blogs, followed by flitting to a couple of ‘inspirational’ Facebook sites, followed by reading my current ‘Christian’ book, followed by studying my current ‘non- Christian authored but pertinent to spirituality and the arts’ book, followed by a period of intercession…. Did I really write ‘double up’?
How is it possible to discern God in all of that at once?!
My last sleight of hand is to make it seem to myself as if I am doing spiritual ‘work’, filling a journal with my reflections and practicing creative writing, when actually all I am doing is copying out copious numbers of quotes with absolutely no pause or application at all.
This is spiritual tourism at its worst: an unthinking regurgitation of the supposedly sacred in the pretence of practicing personal holiness.
(And yes, I get angry at myself for doing it.)
As in all consumerism, this relentless pursuit of the ineffable is driven by anxiety, in turn driven by unacknowledged or repressed desire. In my case, I am eager to learn, but when that eagerness arises from a shadow place, I know I have fallen into a muddle-headed way of approaching my God.
The heart-breaking fact of the matter is that I do ‘game play’ even whilst calling myself a contemplative.
And it is not as if I do not know the corrective: that the Grace I seek is to be found in the here and now.
Stop the merry-go-round, you do want to get off.
Bow down, this moment, you are on holy ground.
Your Beloved beckons.
Loving-kindness and Rest await you.
There are as many methods of spiritual ‘stopping’ as there are people, but the method I have long been attracted to is Centering Prayer (which I came to via Thomas Keating). Practicing this kind of prayer on a daily basis recognises that I need the grounding such an approach gives. I am only too aware that I will be unable to create honestly with a camera or pen in my hand without such rootedness. For someone who has spent the vast majority of the last year in bed, in one place, it’s ironic that I need to be stilled. But to heal the skittering effect of pain, and its accompanying friends grief and frustration, I have come to accept such a calming, stabilising, focussing measure is very much required.
This acceptance is all part of the great movement of Reconciliation within me: am I willing to become present to God in the circumstance in which I find myself? Am I willing to enter into this circumstance and welcome whatever Wisdom God may reveal to me in it? Am I willing to be a witness to the presence of Hope underlying the ordinary, every day experiences of my life? Am I willing to announce that ‘God is in this’, whatever the ‘this’ may be, and however much that defies my own understanding?
Just as I am making small steps out of being in bed all day, perhaps I am making the smallest of steps into this prayer practice. I have at least begun to understand more about the inordinate amount of time I spend with my thoughts: scripting conversations for the future or commentating on past events, (telling myself I am thinking awfully profound thoughts of course). I am learning how these words expand to fill all available space as soon as I decide to sink into silence. I can’t say I am hearing God’s voice as if on a new DAB radio, I can’t even say I have corrected my tendency to scan too many outlets at once and overload my system; but now at least I am trying to intentionally create a space in between, around, above and below, my own words.
A space wherein the Voice, who is in and of all things, might echo.
A space in which I pay attention to that sound above all other.
(William of St Thierry)
Kate Kennington Steer is a writer and photographer with a deep abiding passion for contemplative photography and spirituality. She writes about these things on her shot at ten paces blog.

domain: literature


The trade is abuzz with the news that filmmaker Vipul Shah, post the success of HOLIDAY – A Soldier Is Never Off Duty, is gearing up for his next, a story of three girls. The film that is tentatively titled ZINDAGI EK PAL will star Pooja Chopra, Meera Chopra and newbie Tonisha Pawar, which will be helmed by director Suketu Parekh!
|view VIPUL SHAH AT SHAADI KE SIDE EFFECTS SPECIAL SCREENING
However, when we contacted Vipul, he rubbished the reports saying it is absolutely untrue!
Vipul will directly start his next film with Akshay Kumar by the end of this year!


Photo Gallery: WVU Sports Hall of Fame
MORGANTOWN, W.Va. – The WVU Sports Hall of Fame inducted 11 new members Saturday – Kate Bulger (women’s basketball), Jon Capon (men’s soccer), Avon Cobourne (football), Mike Gansey (men’s basketball), Tom Keane (football), Larry Krutko (football), Eleanor Lamb (administration), Steve Slaton (football), Bev Fry Plocki (gymnastics), Pat White (football) and Web Wright (rifle).
Following are looks at the induction ceremony and introductions during West Virginia’s football win over Kansas State, as well as some looks at the athletes in action during their careers.
Click on any photo to launch the gallery
WVU director of athletics Shane Lyons presents Avon Cobourne with his Hall of Fame plaque.
WVU director of athletics Shane Lyons presents Kate Bulger with her Hall of Fame plaque.
Avon Cobourne slithers through a hole
West Virginia basketball’s Mike Gansey acknowledges the cheers for his career
West Virginia running back Avon Cobourne has a cheering section to acknowledge his introduction
West Virginia running back Steve Slaton and daughter Darla
WVU Rifle National Champion and All-American Web Wright
Steve Slaton puts a move on a Marshall defender
WVU director of athletics Shane Lyons presents Steve Slaton with his Hall of Fame plaque.
The 2018 class of the WVU Sports Hall of Fame
Avon Cobourne (left) and Shane Lyons speak at the 2018 WVU Sports Hall of Fame Induction ceremony.
WVU Sports Hall of Fame running backs Avon Cobourne (left) and Steve Slaton
Mike Gansey and Coley White at the WVU Hall of Fame induction ceremony. Coley accepted on behalf of his brother, Pat White, who was unable to attend because he was coaching at Alcorn State that night.
Tony Caridi served as the Master of Ceremony for the WVU Sports Hall of Fame induction ceremony.
WVU director of athletics Shane Lyons presents Bev (Fry) Plockiwith her Hall of Fame plaque.
Kate Bulger gives her induction speech into the WVU Sports Hall of Fame
Coley White accepted on behalf of his brother, Pat, who was coaching a football game for Alcorn State during the WVU Sports Hall of Fame induction ceremony.
Mike Gansey accepts his induction into the WVU Sports Hall of Fame
Steve Slaton addresses the crowd during the WVU Sports Hall of Fame induction ceremy.
Former WVU athletic department administrator Eleanor Lamb was inducted into the Sports Hall of Fame at the age of 96.
All photos copyright BlueGoldNews.com


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Namak pare, or namak para, is only one of the many different types of Indian namkeen. Namkeen, of course pretty much means snacks. We eat lots of snacks in our house.
Namak pare is really easy to make, simple ingredients, and hardly any time spent in the kitchen. They last quite a while too, if kept in a properly sealed compartment.
- oil, for frying
- 1 cup maida, all purpose flour
- 1/4 cup water
- 1/2 tsp salt
- 1/4 tsp carom seeds, ajwain
- ghee, 2 tbsp
In a bowl, mix together the flour, salt and carom seeds. Incorporate the ghee, so that it is mixed well with the flour. Slowly adding water, mix until you have a stiff dough. Rub some ghee over the dough, cover and let it sit for about 15 minutes.
Divide dough intil equal parts and using a rolling pin, roll out into circles. They need to be not too thin, but not very thick. If you have made chapatis before, they do need to be thicker than chapatis. Using a knife, cut the circles into diamond shapes to form crackers. You can do this by cutting equal strips vertically, then diagonally.
In hot oil, fry the crackers. Flip over once they are golden.
Drain on paper towel.
You can eat them hot or cold. The cooler they get, the crispier they get.
*For healthier version, use whole wheat flour.
*Sprinkle with chaat masala if you wish
Here are some other Indian snacks

domain: food


text:
Modular sofa Mags Soft by HAY
Discover the 3 Mags HAY sofa family
Maximum comfort, minimum details and optimal flexibility in a timeless design.
|The Mags Soft Low sofa is an evolution of the Mags and Mags Soft sofas. It is characterized from the Mags by its softer padding and from the Mags Soft by its lower armrests. Like the latter, it is fitted with visible stitching, available in black, white, light grey, dark gray and beige. The feet, very discreet, are in black pine.|
Choose one of our combinations, or build your own !
|For any advice, do not hesitate to call us: +33 (0)1 43 33 20 12 or come and see the sofas in our showroom.|

domain: design


text:
On Demand TV and Radio for Education
Resource for the study of newsreels and cinemagazines
Full archives of UK Independent Local Radio from 1973 to 1996
Understand How Copyright Regulates the Use of Creative Works in Education
Best practice for citing any kind of audiovisual
Supporting the use of audiovisual content in education.
Have you ever missed recording a broadcast you wanted to use in teaching?
We help you to convert old video recordings or films to digital format
A training and events space in the heart of London
Sorry, it seems that the collections are currently unavailable. Please try again in a few minutes.
Published on: 24th November 2011
Professor Ann Gray and Dr Erin Bell look at how embedded the version of history as presented on television have become in the public consciousness.… continue reading.

domain: library


It really shouldn’t be called that at all.
Yesterday, we said that to the extent the latest “We Are Ohio” ad implies the loophole would be repealed, that is misleading. We then discussed the very provisions this ad rests on and said:
Anyone who claims that state public employee unions oppose Issue 2 because they oppose these limits is lying, plain and simple.
Nothing has changed since yesterday. This ad claims that these provisions will save “Ohio taxpayers money.” To the extent that suggests it will save the people who pay State taxes money. This is a blatant lie. […]Full Story... →
Categories2018 2020 Activism Budget Civil Rights Congressional Races Economy ECOT Education Environment Fair Elections Federal Governor's Race Governor DeWine Guns Health ICYMI Justice Labor LGBT Ohio Legislature Ohio Legislature Plunderbund Plunderbund Action Portman Presidential Safety Senate Race State State Government Statehouse Races Statehouse Races Swing State Voices Taxes and Spending Trump Women's Rights


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Sharara Suits for the Fashionista in You
Sharara suits have been a part of the Indian fashion scene for ages. It was worn by women in the court of Oudh. A sharara is also known as a Farsi pajama and consists of wide pants that imitate the look of a lehenga or ghaghra. A sharara suit ideally consists of three parts namely, the kurta, the wide-legged pants, and a dupatta or veil. Today, shararas are popularly worn during wedding ceremonies or for particular festivals and have permeated cultural divide as women from all religions and regions flaunt a stylish sharara ensemble when the occasion calls for it. If you are planning stylish outfits for your friend’s wedding, then you can opt for a sharara suit for women. You can buy an ideal sharara suit online from online shopping sites like Flipkart that host a range of designer sharara suits from brands such as Fashionuma, W Ethnic, Rustorange and so on. However, before you shop for a sharara set for yourself, here is a quick look at the type of suits you can find online.
Sharara vs Gharara
A sharara is designed after the flare and look of European gowns, hence the legs are flared from the waistline to the bottom. A gharara, on the other hand, comes with more drama. It is form-fitting from the thighs to the knees and then flares out from the knees. A great example of a gharara set in recent movies belongs to Sara Ali Khan’s yellow gharara set in Kedarnath.
Frock Style Kurta with Sharara Pants
Now, that we have established the differences between a sharara and a gharara, let us take a look at the different style of sharara sets. You can pair a frock-style short kurta with sharara pants and complete your look with a dupatta. Such a look is reminiscent of the golden era of the Nawabi culture. If you are planning to attend a day time semi-formal event, you can opt for a simple cotton sharara set with a bold-coloured frock-style kurtis , printed or embroidered sharara pants and contrasting dupatta. If you are dressing for an evening event, you can opt for kurtas and palazzo pants with sequins or beadwork.
Long Kurta with Sharara Set
Long kurta and sharara sets can look graceful and elegant, even give the illusion that a person is wearing a skirt instead of comfortably divided pants. If you are attending a wedding, you can opt for a dark coloured long kurta that is decorated with zari work, or has intricate beadwork and pair it with a golden sharara along with a net dupatta. Complete your look with large jadau earrings, jadau haathphool and maang tikka and you are ready to make heads turn wherever you go.
The above mentioned are a few types of sharara suits available in the market. However, with fashion being all about re-imagination, confidence, and individuality, you can mix and match to create your own sharara set that will help you stand apart from the crowd. So, go ahead and shop for your look today.
Also check our new sarees store ...


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02-16-2012 08:41 PM - edited 02-16-2012 10:21 PM
Today we have a guest blog by author DEBRA WEBB!
Debra has been a guest here before during one of our Romantic Suspense features:
Her website is here: http://debrawebb.com/
She's on Facebook here: https://www.facebook.com/profile.php?id=618226105
And she's on Twitter here: https://twitter.com/#!/debrawebbauthor
DEBRA WEBB, born in Alabama, wrote her first story at age nine and her first romance at thirteen. It wasn’t until she spent three years working for the military behind the Iron Curtain—and a five-year stint with NASA—that she realized her true calling. A collision course between suspense and romance was set.
Since then she has penned nearly 100 novels. The Faces of Evil is her debut thriller series. Visit Debra at www.debrawebb.com or write to her at PO Box 12485, Huntsville, AL, 35815.
02-16-2012 08:47 PM - edited 02-16-2012 10:21 PM
Natalie Collins, Toni McGee Causey, Deborah LeBlanc and Debra Webb, all of Murdershewrites.com
Debra Webb was born in Scottsboro, Alabama, to parents who taught her that anything is possible if you want it badly enough. She loved telling stories and began writing at age nine. Growing up on a farm in rural Alabama provided the wide open spaces and fertile ground for her vivid imagination.
When she met and married the man of her dreams Debra put her writing aside and tried some other occupations, including door-to-door sales, various factories and restaurants, a day care center, a hospital and a department store. Shortly after the birth of her first daughter Debra’s husband joined the military and she decided to go to college. Eventually the U.S. Army took them to Berlin, Germany, and Debra accepted a position as secretary in the commanding general's office. By 1985, they were back in the States, and her next major career move landed her at NASA in the Space Shuttle Program.
For more than a dozen years after returning to the States Debra and her family lived in a small Tennessee town where everyone knew everyone else. A few years after settling in Tennessee her second daughter was born. Though she hadn’t written in nearly two decades, in 1996 Debra took up writing again. With the support of her family and God’s blessing her dream of being published came true in March of 1999.
Debra’s life has come full circle now. She and her family, along with their three dogs, have moved back home to Alabama. As a multi-published, best selling author Debra writes spine-tingling romantic suspense for St. Martin’s Press and Harlequin Intrigue. She has just launched her first thriller series, the Faces of Evil, with the debut novel OBSESSION.
Debra is represented by literary agent Stephanie Kip Rostan of the Levine-Greenberg Agency (www.levinegreenberg.com). For foreign rights requests please contact Beth Fisher ( email@example.com ).
Watch for Debra every other Tuesday on www.murdershewrites.com!
02-16-2012 08:47 PM - edited 02-16-2012 09:59 PM
More exciting news! OBSESSION is #7 on the Top 10 Indie Best Seller list for the second week in a row! Check it out at http://indiereader.com/the-list-where-indies-count
I'm looking forward to spring. We've planted tulip and day lily bulbs. The tulips are peeking through the mulch. I can't wait to see them in bloom! We found flower boxes for my two favorite windows on the house. I'm so excited! I've always wanted flower boxes brimming with lots of pretty colors. I'll post pictures in the spring.
POWER, the next Faces of Evil book, is coming March 16th. A little slower than I hoped but I'm working hard so please bear with me! Look for RAGE in May, then REVENGE in late June. Big news on the special Colby Agency trilogy in May, June and July. Not only will it herald in the 50th installment of the Colby Agency but the Colby Companion I annouced late last year will be included in the 50th book as my gift to you!
I want to say again how much I appreciate the continued support of all my loyal readers.Because of all of you I look forward to a hugely successful 2012!
As a special thanks, each quarter this year I will be giving away a one-year subscription to RT Book Reviews magazine! And in July as well as December I will be giving away a Nook! So if you haven't signed up for my newsletter yet, be sure to do so since I'll send out annoucements about those events.
You can follow me on twitter at https://twitter.com/#!/DebraWebbAuthor and on Facebook
Look for a more news each month in 2012!
Watch for Debra every other Tuesday on www.murdershewrites.com!
02-16-2012 10:07 PM
02-16-2012 10:07 PM
These are NookBooks - I hope I got them all!
02-16-2012 10:12 PM
02-16-2012 10:16 PM
02-16-2012 10:20 PM
OBSESSION makes the Top 10 Indie Best Seller List! The Faces of Evil series is my first Thriller series and I am loving the challenge. OBSESSION is the debut and IMPULSE is now available. These two stories are only the beginning! The series will span 12 stories.
Special Agent Jess Harris has spent more than a decade studying the many faces of evil. But in her determination to stop a heinous serial killer, she messed up, broke the rules, and it cost her everything. Now her career is in need of resuscitation and her love life is dead and buried. Jess jumps at the chance to escape her current reality and to advise on a case that has Birmingham, Alabama’s top cops stumped. The trouble is, the case forces Jess to confront all the reasons she put her hometown and her first love, Police Chief Dan Burnett, in her rearview mirror all those years ago.
Dan Burnett will do anything to find the four young women who have gone missing before it’s too late to save them—even if it means asking for help from the woman who has spent a decade avoiding him. Until recently he kept up with Jess’s career at Quantico. She’s the best at what she does and he needs her to help him solve this case. And just maybe, in the process, they can break down that brick wall she has built between them. Maybe they can even be more than friends again.
When a fifth girl goes missing without a break in the case, Jess questions her skill as a profiler and an investigator. Then the unthinkable happens. A startling personal message reveals that the crazed serial killer whose case she blew has followed her to Birmingham, adding a chilling twist to an already desperate situation, and time is swiftly running out.
02-16-2012 10:28 PM
Welcome to the Colby Agency, home of the most private investigations. You’ll find Victoria and her staff of venerable investigators on the fourth floor of a grand old building just off Chicago’s glamorous Magnificent Mile. The Colby Agency has a reputation that spans more than two decades. Look for the titles below at your favorite bookstore to share in the excitement of the one and only Colby Agency!
CELEBRATING TEN YEARS OF THE COLBY AGENCY!!!
02-16-2012 10:29 PM
Going the Distance with a Series
by Debra Webb
I’ve written several stand-alone stories. I love stand-alone stories, but series are my heart. The characters become like family. The Colby Agency series I write for Harlequin Intrigue has stood the test of time, going into its twelfth year! As much as I enjoy the Colbys, I really wanted to do a more mainstream series where I could dig deeper with the characters and explore more chilling plot twists.
A certain character had been lounging around in my head for a while, just biding her time and waiting for her turn. Her name is Jessie Lee Harris and she has spent seventeen years working with the FBI. Her parents passed away when she was very young and she and her sister spent their formative years in foster homes. Upon graduating high school, Jess couldn’t wait to put her hometown of Birmingham, Alabama, in her rearview mirror. She and her high school sweetheart, Dan Burnett, left for college full of passion and with big dreams. But sometimes passion fizzles and dreams don’t always come true. Four years later Dan returned to Birmingham and Jess went on to become a celebrated profiler for the Bureau.
Fast-forward twenty years and things have changed again. Jess’s personal and professional life are crashing down around her. On administrative leave after a bumbled investigation that resulted in a suspected serial killer going free, Jess welcomes an unexpected invitation to escape from her current reality. Her expertise is needed on a case involving four missing young women. The problem is, the case is in Birmingham and the top cop is Chief of Police Dan Burnett.
Jess finds herself spiraling into the past that she’d thought she left behind. And if having sparks fly between her and Dan isn’t frustrating and distracting enough, the serial killer who got away has followed her to Birmingham!
As I brainstormed the series, I revisited a concept I had developed a few years ago called the Scales of Justice. The idea was to have a series where each book focused on a different level of that scale, beginning with the least heinous of intents. The Scales of Justice seemed to scream courtroom and that side of justice and that wasn’t where I wanted to go. After much consideration, I came up with the Faces of Evil. The stories are more about the motive for the crime than the crime itself. Of course, the goal is to solve the mystery and the case but in Jess’s opinion the crime is all about motive. The motive, she swears, will reveal the identity of the one committing the crime. This is Jess’s summation of evil:
Any act of evil committed by one or more persons against another is driven by motive. Every motive tells a unique personal story, painting a vivid picture that reveals the dark inner nature hidden beneath the image presented for the world to see. All of us possess a basic goodness, but we each also harbor the potential for evil. The choice not to cross that moral line ultimately separates the good from the bad. For those who cross that line life’s journey is forever altered. Where that journey begins and how far one drifts into the depths of depravity is fueled by desire and desperation. Some plummet directly into the deepest, blackest recesses of that hungry abyss. Others linger near that thin line, clinging to a rapidly unraveling thread of goodness while the darkness seduces them closer and closer until the thread snaps and evil is born.
As a writer, I found the concept immensely interesting. The Faces of Evil series will span twelve books and Jess and Dan will be the main protagonists for the entire series. Their personal relationship as well as their professional one will evolve over those twelve installments. There are several compelling secondary characters, like Sergeants Harper and Wells, who I adore! The ensemble cast gives the stories a sense of family and place. And though there is murder in every story, it’s discovering the motive which leads to the killer that I, and the characters, find the most exhilarating. But don’t be fooled by the puzzling mystery or the layers of suspense, each of the Faces of Evil stories are about the characters. The primary focus is Jess and Dan and how their work and everyday life impacts their determination to be strong and independent while coming to terms with the idea that neither is complete without the other.
Another cool and challenging aspect of the stories is that the next book takes up right where the last left off. I wanted to show the day-to-day life of these characters during and after the cases they investigate. I’m also working extra hard to create unique villains and plot twists. I’ll let the readers be the judge of whether I’m successful!
The release dates are on an intense schedule as well. OBSESSION was released at the end of October; IMPULSE came the first of December; POWER is out next month; and RAGE is set for early May!
I hope you’ll enjoy Jess and Dan’s journey!
Do you love series when it comes to books or do you prefer stand-alones? What’s your favorite book series?
02-17-2012 09:12 AM
Hi Deb, another Deb here to say hello Happy Friday and Welcome
I have read and loved many of your novels, the one's that still stick with me are
they were soooooo good
02-17-2012 09:29 AM
I am looking forward to reading your newest book ! I am now reading one, and love your writing ! I didnt realize you have 100 books, thats amazing, congrats !! It also means I have alot of catching up to do !!
Happy Spring ~
02-17-2012 10:00 AM
Thanks, everyone! I've written a lot of books but I have to say that the Faces of Evil is my fav series. OBSESSION will always hold a very special place in my heart! The series helped me get past the horrific tragedy I suffered in 2010!
02-17-2012 10:08 AM


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Strategically located in the historic district of the financial metropolis Zurich, the Five-Star Widder Hotel, is a glamorous location for social events and important conferences. Through its unique art collection and architecture, the Widder Hotel is also a meeting place for creative people who appreciate the exceptional personal ambience of this individually designed hotel.
The Widder Hotel is in the heart of Zurich’s old city and known for its exceptional architecture: The nine private residences from the middle Ages have been meticulously restored and renovated into one modern luxury hotel. Discerning leisure and business travelers always note that the Widder Hotel is a member of Swiss Deluxe Hotels, White Line Hotels, and the Leading Hotels of the World. Since 2010, Mr. Jan E. Brucker as the manager of the hotel took on the honorary position of President of Swiss Deluxe Hotels (SDH).
The association was founded in 1934 and includes 39 of the best, independently managed Five Star Hotels in Switzerland. Many of the historical traces, that distinguish the Widder Hotel, are found in the guestrooms. The visitor will need to come several times to experience all architectural and artistic features of the hotel. Each guestroom has its individual layout, structure and color scheme and shines with a distinct design and furnishing.
According to Mr. Brucker, the Widder Hotel attaches great importance to real values. It does not mean to be trendy, but rather stands for the true values of the arts, history and heritage and in fact the main attraction of the Widder is the preserved historical, complemented by permanent values.
The nine meticulously restored historical residences in which the Widder Hotel unfolds are unique, as each house is underlined by a subtle guide of orientation with the colour of each house also applied to the inside gangways and corridors. Moreover each house features its own wood species and stone.
Each one of the 34 guest rooms and 15 suites, the banqueting room, meeting rooms, restaurant and bar are individually styled The fusion of historical architecture and innovative modern design creates a relaxed ambience with real character. It’s the perfect setting for an unforgettable stay, private party or exclusive business event.
The hotel has been built, acquired, occupied, changed and decorated by descendants of noble families, guild masters, artisans and merchants. And their life took place in little parlours and offices just the same as in opulent salons. The room decors of these late Middle Age houses with rich murals and stucco is an expression of the owners’ social class, who made their wealth and fortune through trade and commerce. The “Rennweg”, where the main entrance of the Widder Hotel is located, was Zurich’s most prestigious street from the 17th to the 19th century.
Every room is furnished with a sophisticated lighting system by the Austrian Zumtobel Group and has two telephone lines as well as fax- and WLAN-connections. The audio system is by Bang & Olufsen. Satellite TV, a personal safe and a cooling/heating system as well as mini bar and Nespresso coffee maker are also standard facilities in each room.
Guests occupying a suite have an iPad available free of charge during their stay. Each suite is equipped with an Apple Docking-station, allowing further options for use such as playing music or listening to audio books.
A team of preservationists, archaeologists, architects and designers, through the years were involved in the reformation of this historical building ensemble. During the 18 months of archaeological excavation the scientists even found relics from the Roman Ages, among them a fire place as well as cooking utensils and domestic ceramics. In the Widder Hotel all of the ancient and antique is genuine, all new elements are state-of-the-art.
In the raised upper floor of the Steinhaus there is the light and airy breakfast room with its retractable glass ceiling. The library is located on the ground floor of the Steinhaus. The antiques and works by renowned artists, in particular from contemporary times, lend the hotel its own distinctive character. Robert Rauschenberg has designed and created a picture especially for the stairway in the Penthouse Suite.
A wealth of paintings, sculptures and artworks adorn the lobby, restaurants, conference facilities and all guest rooms from famous artists such as Augusto Giacometti, Serge Poliakoff, Max Bill, Andy Warhol.
The Widder Garden is Zurich’s most loved open-air-hideaway when the weather is good for alfresco dining. Located in the heart of the historic district, enjoy a light lunch or cappuccino-break after shopping and sightseeing, to an afterwork dinner in the evening in one of the hotel’s restaurants serving world-class cuisine.
The Widder Hotel lies in the heart of the Augustiner quarter, which offers all benefits of a central location within the historic section of the town and offers Maserati limousine transfers to and from the airport.
#travel #TravelJunkie #TravelTheWorld #wanderlust #globalista #wanderer #explore #discover #traveladdict #destinations #adventure #GoingPlaces #holiday #ShereenShabnam #OutAndAbout #Tourist #LuxuryTravel #ShereenOnTheRoad #TravellingIslander #TravelDiary #Beautiful #AmazingPlaces #TravellingFijian #Globetrotter #SeeTheWorld #Traveller#OffTheBeatenTrack @Shereen_Shabnam

domain: travel


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While the army of Anton Castillo may be the most significant obstacle for Far Cry 6 players attempting to liberate the island of Yara, the second obstacle is the island’s hostile wildlife. Among the animals encountered, one the most deadly is the crocodile.
On the west coast of the Aguas Lindas region, Far Cry 6 players can explore a large Crocodile sanctuary that has become overrun by the deadly reptiles. At this location, players are able to accept the “Crocodile Tears” treasure.
Crocodile Tears Treasure Hunt Guide in Far Cry 6
After arriving at the location, interact with the document in the marked orange container. In the document, one of the sanctuary employees describes an attempt by Castillo’s troops to enter his residence on the property and how he always keeps the key on his person.
Next to the employee letter, players will find several crocodile head souvenirs. Pick up all the heads in the admission booth as they will be required for one of the main operations later in the campaign.
After collecting the heads, proceed south along the path before reaching a large area overlooking the Far Cry crocodile pens. From the overlook, players should see the deceased employee’s body next to a shack with a red roof.
Jump down into the pen and head towards the body. Players should be warned that after jumping into the pen, several crocodiles will attack the player.
After defeating the crocodiles, inspect the body of the employee. Players will notice that the arm of the employee that presumably held the key is missing.
Once players inspect the body, his prized crocodile “Beatrice” will emerge from the nearby shed. Defeat the crocodile to obtain the employee’s house key.
Head back to the wooden platform overlooking the crocodile pens and proceed down the walkway towards the large radio tower. At this location, players will be able to swing from the radio tower with their grappling hook towards the employee’s house on the opposite side.
Enter the house and open the chest to obtain the 3-star “Surf & Turf” rifle. Like previous Treasure Hunt rewards, the Surf & Turf rifle is a unique weapon and cannot be modified through the workshop.
The weapon’s unique attributes include bonus damage for shooting enemies below the player and a significantly increased magazine size. The one major downside to the gun is that it is unfortunately unsuppressed, making its use limited for stealth players.
Far Cry 6 releases October 7 for PC, PS4, PS5, Stadia, Xbox One, and Xbox Series X.

domain: hobby


- Is 120hz better than 60hz?
- How much does refresh rate matter on a TV?
- Does high FPS matter on 60hz?
- How important is the refresh rate on a TV?
- Which is better 4k or UHD?
- Can 60hz run 120fps?
- Is 4k worth it 2020?
- How many FPS can a human eye see?
- Is 60hz good for 4k gaming?
- Is high refresh rate bad for your eyes?
- How do I increase the refresh rate on my TV?
- Is 4k 120hz possible?
- Is 50hz good for 4k?
- Is it better to have a higher or lower refresh rate?
- Is refresh rate important on 4k TV?
- What’s the refresh rate on a 4k TV?
- Can you tell the difference between 1080p and 4k?
- Do you need 4k HDMI?
- How many FPS can a 120hz monitor display?
- Which TVS are true 120hz?
- Is 4k overrated?
Is 120hz better than 60hz?
A 60Hz display refreshes 60 times per second, 90Hz is 90 times per second, and 120Hz is 120 times per second.
120Hz refreshes four times faster than 30Hz and two times quicker than 60Hz, producing smoother motion and transitions..
How much does refresh rate matter on a TV?
Although manufacturers would like you to believe that 120Hz TVs are inherently better than their 60Hz counterparts, the refresh rate itself does not directly improve the motion performance of a TV. In theory, 120Hz is definitely better; as the screen is refreshed twice as often, motion should look better.
Does high FPS matter on 60hz?
In this case the monitor’s refresh rate doesn’t matter because the frame rate is just used as a number to measure the gaming performance. A higher frame rate is better. … This does limit your framerate exactly to the refresh rate. For example, if your refresh rate is 60Hz, VSync will cap your framerate to 60 FPS.
How important is the refresh rate on a TV?
A TV with a high refresh rate of 120 Hz vs 60 Hz will have better picture quality. You’ll hear about many different frame rates, from 60 Hz to 120 Hz to 240 Hz and higher, when searching for a new TV. Most LCD sets you’ll find will have an actual refresh rate of 60 Hz.
Which is better 4k or UHD?
The simplest way of defining the difference between 4K and UHD is this: 4K is a professional production and cinema standard, while UHD is a consumer display and broadcast standard. … UHD quadruples that resolution to 3,840 by 2,160.
Can 60hz run 120fps?
Originally Answered: Can a 60Hz monitor run 100 FPS? In short, No. A 60 Hz monitor basically refreshes the panel 60 times every second, which is basically 60 frames per second. So even if hardware capable of higher frame rates is plugged into a 60Hz monitor, the monitor output will be capped at 60FPS.
Is 4k worth it 2020?
So is buying a 4K still worth it? The quick answer here is yes if you’re planning to take advantage of the 4K resolution. If you don’t, then you’re better off with a 1080p resolution. … While 4K models are starting to become more affordable because of commercialization, it’s not in the most affordable pricing yet.
How many FPS can a human eye see?
How many frames per second do you think you can see? Some experts will tell you that the human eye can see between 30 and 60 frames per second. Some maintain that it’s not really possible for the human eye to perceive more than 60 frames per second.
Is 60hz good for 4k gaming?
Originally Answered: Is 60Hz good for 4k gaming? 60Hz is fine. Most computers and graphic cards can’t exceed the capabilities of that monitor. With that said a 120-144Hz display is better if your brain and eyes are physically capable of seeing the difference.
Is high refresh rate bad for your eyes?
A higher refresh rate means a smoother-looking screen that’s easier on the eyes. So, if you’re trying to ease your eyestrain, a refresh rate of 120 Hz is optimal. … Unless you’re doing heavy gaming or video watching and editing, you most likely won’t see the difference between 120 Hz and anything higher.
How do I increase the refresh rate on my TV?
How to Improve Refresh Rates on Your TVEnsure the native resolution of the incoming signal matches the resolution of the set. … Use 24 hertz on Blu-ray sources, if your set and player support this. … Make sure all other video sources are running at 59.94 hertz.
Is 4k 120hz possible?
In theory, though, HDMI 2.0 (effectively HDMI 2.0b since late 2016) can do 4K 120Hz. This mostly applies to PC, where cards like the GTX 2080 Ti can actually pull off 120 frames per second in certain games while running in 4K. The PS4 Pro and Xbox One X won’t allow 120Hz in 4K anyway.
Is 50hz good for 4k?
We’ve covered this before, with 1080p HDTVs, and it’s the same idea with 4K TVs. Certain parts of the world have TVs that refresh at 50Hz normally, with some TVs that refresh at 100Hz. That just depends on the electricity in your country. For the purposes of this article, 50 and 60 work the same, as do 100 and 120.
Is it better to have a higher or lower refresh rate?
A refresh rate measures how many times a screen can update in one second. Higher refresh rates are associated with better video quality, reduced eye strain, and even improved gaming experiences. And while 60 Hz has been the bare minimum for decades, a 75 Hz monitor offers an accessible upgrade.
Is refresh rate important on 4k TV?
Higher refresh rates mean more updates and, presumably, smoother motion. All TVs must have a refresh rate of at least 60Hz, since that’s what the broadcast standard. However, you’ll see 4K TVs with “effective refresh rates” of 120Hz, 240Hz, or higher.
What’s the refresh rate on a 4k TV?
120 HzThe refresh rate on a 4K TV will often be 120 Hz. Even though some will claim to have more! Cheaper models may only be 60 Hz. In the guide to the best OLED and LED flat screen TVs in 2020, I include the refresh rates of the featured models.
Can you tell the difference between 1080p and 4k?
The difference between 1080p and 4K is undeniable in that a 4K screen is capable of displaying four times the number of pixels as a 1080p screen. … From a distance, it is virtually impossible for someone to tell the difference in quality between a 1080p and 4K screen.
Do you need 4k HDMI?
You do not need a new HDMI cable for Ultra HD 4K (probably). We’re well into the transition to Ultra HD “4K.” Most mid- and high-end TVs are now Ultra HD resolution, with many also supporting HDR. … So here’s the short version: There are only four kinds of HDMI cables for the home: High-speed with Ethernet.
How many FPS can a 120hz monitor display?
A 120Hz display refreshes twice as quickly as a 60Hz display, so it can display up to 120fps, and a 240Hz display can handle up to 240fps. This will eliminate tearing in most games. Frame syncing technologies like V-Sync, Freesync, and G-Sync also help prevent screen tearing, but they have their own drawbacks.
Which TVS are true 120hz?
TCL.SAMSUNG.LG.Sony.INSIGNIA.VIZIO.Hisense.Sceptre. Skyworth. ELEMENT. See more.
Is 4k overrated?
Unless people are willing to spend $699 on a console, it’s just not going to happen, at least for this gen. 4K hardware is still too expensive and most people are not willing to spend anything more than $399 on a console. … 4K is vastly overrated IMO and probably just a marketing strategy.


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Auroshikha candles and incense sandal large round flower candle
Hand-crafted in India. Decorated with dried flowers and scented with natural essential oils, these elegant candles make a wonderful gift. The natural fragrances evoke the joy of nature, the dried flowers add a touch of simple beauty. No artificial colors or fragrances. Guaranteed non-toxic.
Please Read Item Label and Packaging for Recent Product Information.
Place lit candle in an upright position on plate or other nonflammable surface.
Protect from wind and keep the wick trimmed to approximately 1 cm for even burning. Allow a new candle to burn until the top is filled with wax, this will prevent the formation of a wall.
Shipping Weight : 0.40 lb

domain: artistic


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Population 124,000 (includes approx. 24,000 students)
Cambridge, England (U.K.)
Following the Roman withdrawal from Britain around 410, the location may have been abandoned by the Britons, although the site is usually identified as the Cair Grauth listed among the 28 cities of Britain by the History of the Britons. There is evidence that the invading Saxons had begun occupying the area by the end of the century. Their settlement—also on and around Castle Hill—became known as Grantebrycge ("Granta-bridge"). By Middle English, the name of the settlement had changed to "Cambridge" and the upper stretches of the Granta changed their name to match.
The arrival of the Vikings in Cambridge was recorded in the Anglo-Saxon Chronicle in 875. Viking rule, the Danelaw, had been imposed by 878. The Vikings' vigorous trading habits caused Cambridge to grow rapidly. During this period the centre of the town shifted from Castle Hill on the left bank of the river to the area now known as the Quayside on the right bank. After the Viking period, the Saxons enjoyed a return to power, building churches such as St Bene't's Church, wharves, merchant houses and a mint, which produced coins with the town's name abbreviated to "Grant".
Cambridge played a significant role in the early part of the English Civil War as it was the headquarters of the Eastern Counties Association, an organisation administering a regional East Anglian army, which became the mainstay of the Parliamentarian military effort prior to the formation of the New Model Army. In 1643 control of the town was given by Parliament to Oliver Cromwell, who had been educated at the University's Sidney Sussex College. The town's castle was fortified, with troops garrisoned there and some bridges destroyed to aid the defence. Although Royalist forces came within 2 miles (3 km) of the town in 1644, the defences were never used and the garrison was stood down the following year.
During the Second World War, Cambridge was an important centre for defence of the east coast. The town became a military centre, with an R.A.F. training centre and the regional headquarters for Norfolk, Suffolk, Essex, Cambridgeshire, Huntingdonshire, Hertfordshire, and Bedfordshire established during the conflict. The town itself escaped relatively lightly from German bombing raids, which were mainly targeted at the railway. 29 people were killed and no historic buildings were damaged. In 1944, a secret meeting of military leaders held in Trinity College laid the foundation for the allied invasion of Europe. During the war Cambridge served as an evacuation centre for over 7,000 people from London, as well as for parts of the University of London.
Cambridge was granted its city charter in 1951 in recognition of its history, administrative importance and economic success.
The city gained its second University in 1992 when Anglia Polytechnic became Anglia Polytechnic University. Renamed Anglia Ruskin University in 2005, the institution has its origins in the Cambridge School of Art opened in 1858 by John Ruskin. The Open University also has a presence in the city, with an office operating on Hills Road.
By Andrew Dunn - http://www.andrewdunnphoto.com/, CC BY-SA 2.0, https://commons.wikimedia.org/w/index.php?curid=1340715
Cambridge is a university city and the county town of Cambridgeshire, England, on the River Cam about 50 miles (80 km) north of London. At the United Kingdom Census 2011, its population was 123,867, including 24,488 students.
Cambridge is the home of the University of Cambridge, founded in 1209 and one of the top five universities in the world. The university includes the Cavendish Laboratory, King's College Chapel, and the Cambridge University Library.
Cambridge is at the heart of the high-technology Silicon Fen with industries such as software and bioscience and many start-up companies spun out of the university. Cambridge is also home to the Cambridge Biomedical Campus, one of the largest biomedical research clusters in the world, soon to be home to AstraZeneca, a hotel and relocated Papworth Hospital.
- Pray for God to raise up night and day worship that would overflow in mission to the ends of the earth.
- Pray for a multiplying movement of simple discipleship to spread throughout the city and beyond.
- Pray for university students to encounter the truth and power of the resurrected Jesus.
- Pray for Cambridge's many international visitors to connect with Christians and hear about God's love for the nations.
- Pray for a revival of Cambridge's heritage of reformation and student mission.
- Pray and ask God how you can be involved!

domain: history


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Tapestry, Inc., formerly known as Coach Inc., provides luxury accessories and lifestyle collections for women and men in the United States and internationally. Product offerings include modern luxury accessories and lifestyle collections, including women's and men's bags, women's and men's small leather-goods, business cases, footwear, wearables including outerwear, watches, weekend and travel accessories, scarves, sunwear, fragrance, jewelry, travel bags and other lifestyle products. The company was founded in 1941 and is based in New York, New York.
TPR Price Forecast Based on DCF Valuation
DCF Fair Value Target:
We started the process of determining a valid price forecast for Tapestry Inc with a discounted cash flow analysis -- the results of which can be found in the table below. To summarize, we found that Tapestry Inc ranked in the 49th percentile in terms of potential gain offered. More precisely, our analysis suggests the stock is undervalued by approximately 47% on a DCF basis. In terms of the factors that were most noteworthy in this DCF analysis for TPR, they are:
In the past 5.48 years, Tapestry Inc has a compound free cash flow growth rate of -0.08%; that's better than only 18.22% of cash flow producing equities in the Consumer Cyclical sector, where it is classified.
Tapestry Inc's weighted average cost of capital (WACC) is 5%; for context, that number is higher than just 3.62% of tickers in our DCF set.
TPR's estimated cost of debt, based largely on its market capitalization and its interest coverage ratio, is 2%; for context, that number is higher than just 3.62% of tickers in our DCF set.
Terminal Growth Rate in Free Cash Flow
Return Relative to Current Share Price
For other companies in the Consumer Cyclical that have a similar discounted cashflow valuation profile (and ensuing price forecasts) as TPR, try CATO, DAN, TSCO, CVCO, and RL.

domain: finance


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Here is another item on my To Do list today! The nice thing about Fire Cider is you can change it and add things that you feel drawn to do so. This is really good to have on hand as we go into the winter months. It takes a month…from full moon to full moon to make so you may want to get it started now…..
You can read the rest of the article at the following link:
©11142016 Wolf Woman Ways


EnginSoft USA Joins PTC Partner Network for Creo and Creo Simulation Live
Posted by Donald Hood on March 19th, 2019
(1888 PressRelease) PTC and EnginSoft USA partner to solve customer problems with Creo Simulation Live.
MCKINNEY, Texas – EnginSoft USA, global experts in mechanical engineering simulation, announced today its joining of the PTC Partner Network as a distributor and service provider for PTC’s Creo® design product, specializing in Creo Simulation Live.
EnginSoft USA provides clients with customized solutions for complex simulations. Founded in 1984, they are part of an Italian-based multinational simulation company that has worked with organizations across a broad range of industries, including automotive, aerospace, defense, energy, civil engineering, consumer goods and biomechanics. Over the past 30 years, the company has helped its clients maximize the potential of over 3,000 engineering simulation projects using industry-leading technology.
“PTC’s Creo Simulation Live is real-time simulation functionality powered by ANSYS Discovery Live technology, which is deeply integrated into the design workflows in Creo. With Creo Simulation Live, Creo users get instant insight into the impact of their design decisions as they make them. This breakthrough technology will help deliver on the promise of simulation-driven design,” said Brian Thompson, senior vice president, CAD Segment, PTC. “The executives at EnginSoft USA, Chris Wilkes and Dr. Andreas Vlahinos, have been working with PTC for many years and have built excellent reputations in the CAE industry. I am delighted that EnginSoft USA will be bringing the value of Creo with Creo Simulation Live to their customers.”
“We are proud to partner with PTC to deliver Creo and Creo Simulation Live,” says Chris Wilkes, CEO, EnginSoft USA. “Companies in all industries are seeing the need for rapid simulation to narrow the design space. Creo Simulation Live will be an important part of the process for all Creo customers who need real-time simulation for a shortened time to market. More simulations can result in higher quality parts that are much more likely to meet customer requirements.”
About EnginSoft USA
PTC and Creo are trademarks or registered trademarks of PTC Inc. and/or its subsidiaries in the United States and other countries.
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About the AuthorDonald Hood
Joined: August 5th, 2017
Articles Posted: 475
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It looks like Eddie Murphy will finally be returning to a dramatic role. It’s just been confirmed that the former SNL comedian will be starring in a brand new film directed by Lee Daniels. Daniels posted a photo of himself and Murphy on his Instagram, hinting at Eddie’s involvement.
This new biopic will be based on the life of Richard Pryor and Murphy is set to play LeRoy “Buck Carter” Pryor, Richard Pryor’s father. Mike Epps has been cast as the now deceased comedian, with Kate Hudson playing his former wife, Jennifer Pryor.
This will be Murphy’s first dramatic role since his appearance in the box office hit Dreamgirls in 2006. He’s been spending most of his time writing music and doing comedy so this will be a nice change of pace. His recent actions on SNL’s 40th anniversary caused a lot of controversy, so it will be interesting to see how audiences react to him on the big screen. Hopefully he still has the acting chops to pull off this dramatic role.

domain: celebrity


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Numerical and experimental investigations on capillary-driven thin-film evaporation with applications in pumped two-phase loop and loop thermosyphon
Thin-film evaporation in solid-liquid-vapor interface has been the focal point of engineering research and industrial applications for decades. The objective of this dissertation is to systematically investigate the surface-tension (capillary)-driven thin-film evaporation in porous media and of a sessile droplet on a solid substrate using computational experimental methods. In Chapter 2, a mechanical-capillary-driven (hybrid) two-phase loop (HTPL) was used as a test platform to study the capillary-driven thin-film evaporation at a system level. Deionized water is the working fluid for the HTPL. A computational model for the HTPL using a thermal-hydraulic network was developed to predict the steady-state thermal performance and the evaporation mode transition in the HTPL. It was found that there are three distinctive evaporation modes (flooded, partially flooded, and capillary) which are determined by the pressure conditions in the liquid and vapor volumes of the evaporator. As the heat input increases, the evaporation mode is shifted from flooded to partially flooded to capillary mode. The capillary limit, the maximum heat flux limit of the thin-film evaporation, is raised by increasing the mechanical pump flow rate. In Chapter 3, a loop thermosyphon as a passive system was used to study the effects of the evaporator wick structure and properties on the capillary-driven thin-film evaporation. The effects of the evaporator wick base thickness and wick permeability on the evaporator thermal resistance and the capillary heat flux limit were numerically analyzed. A monolayer wick, which was made of mono-size sintered copper particles embedded in a single layer of a wire mesh, was used in the evaporator to lower the thermal resistance. The thermophysical and hydrodynamic properties (e.g. thermal resistance and permeability) of the monolayer wick for various liquid levels were calculated by computational fluid dynamics (CFD) simulations. A thermal-hydraulic network model of the loop thermosyphon was used to study the evaporation mode transition in the monolayer wick in the evaporator. The thermal-hydraulic network model was experimentally validated by the experimental results for three different evaporator designs employing multilayer and monolayer wick bases, and porous and tubular wick posts. The evaporation mode transition from flooded to thin-film evaporation was detected by the evaporator thermal resistance which is directly related with the liquid level in the monolayer wick base. In Chapter 4, an active flow control scheme was developed for the HTPL in an effort to control the capillary-driven thin-film evaporation in the evaporator. The relation between the capillary pressure head and the evaporation modes was established and used for the active flow control. An active flow algorithm was developed to control the mechanical pump flow rate to maintain the capillary pressure head in the evaporator constant, while operating under varying heat input. It was found that the active flow control greatly extends the operating range of the HTPL using the capillary thin-film evaporation and significantly reduces the pumping power consumption compared to a constant flow operation. The robustness of the active flow control was confirmed by operating the HTPL under a dynamic (on-off) heat input cycle along with the active control successfully to maintain the capillary pressure head at a preset value without temperature overshooting. In Chapter 5, the surface evaporation of a sessile droplet on solid substrates was numerically and experimentally investigated. A CFD model was developed to analyze the heat and mass transfer for the surface evaporation of a water droplet on solid substrates in ambient. The results from the CFD simulations were in good agreement with the experimental results for a water droplet evaporation on a hydrophobic-coated silicon substrate. It was found from the CFD simulations that the thermocapillary-driven flow (the Marangoni flow) and natural convection play a great role in the droplet evaporation and internal liquid circulation in the droplet. The effects of contact angle, thermal conductivity of the substrate, and ambient humidity on the droplet evaporation were numerically investigated and the results are discussed.

domain: chemistry


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As mentioned in a previous posting, the AccessText Network is working to make it easier for colleges and universities to provide course materials to students with disabilities. The initiative consists of an online database that aggregates publisher information to allow institutions to order electronic versions of the content or gain permission to scan course materials.
According to a recent article from eSchool News, the service is currently in beta testing and will officially launch in July 2010 but already more than 650 colleges and universities have enrolled. The article reports that with the system, orders can be fulfilled in about four days and already 3,000 requests have been fulfilled since August. Without AccessText, it can take weeks or months for students with disabilities to receive their textbooks. In addition, members of the network are able to access the publishers that produce 92 percent of the college textbooks on the market.
Mike Shuttic, president of the Association on Higher Education and Disability (AHEAD), commented that AccessText Network is "a significant step forward that combines stakeholder resources and addresses the rights of students with disabilities. I encourage every member of the disability community to coalesce around this solution, ensuring its success."

domain: news


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Small businesses are in crisis following the devastation caused by a week of looting and vandalism which swept across Gauteng and KwaZulu Natal last week. What began as a response by supporters of the former President Jacob Zuma, soon descended into rampant destruction affecting hundreds of small businesses and costing South Africa’s already fragile economy billions. So says Alef Meulenberg, CEO of Afrika Tikkun NPC, observing the aftermath of the violent looting sprees.
Township economies have suffered most as a result of the impulsive and misguided acts of those who took part in looting, targeting the same small businesses which are the backbone of these communities. Responding to the call to join hands with communities in repairing some of the damage done, Afrika Tikkun NPC has launched its #RevivingTownshipEconomies initiative. The initiative aims to assist in the rebuilding of community-based organisations severely affected by the protests across South Africa.
“It is extremely disheartening to witness the destruction and weakening of structures and businesses that are the fabric of vibrant communities,” says Meulenberg. “It is these very structures that have helped us build relationships in these communities that have helped our services impact even the most hard-to-reach places especially during the Covid-19 hard lockdowns.”
The urgency of the situation small businesses find themselves in cannot be understated. The damages caused by the protests are estimated at more than R5 billion for the retail industry alone, according to analysis by Business Leadership South Africa. More than 800 stores have reportedly been looted and 100 completely burnt.
“We now look forward to working with various concerned parties to begin to rebuild township economies one business at a time. The strategies and resources that go into supporting small businesses are designed for the long-haul and we aim to create a lasting impact on the businesses we support that will also benefit the communities that rely on them.” Our partners at Afrika Tikkun Services are also providing support for this initiative in the form of training resources.
Afrika Tikkun has begun the selection process for small medium businesses to receive support, particularly in the hard-hit Greater Johannesburg Region. The NPC will soon extend their support to other affected areas in the country. Organisations will be contacted to identify their needs both in terms of funding and other resources.
The success Afrika Tikkun has achieved over the past 27 years is largely owed to strong partnerships with a range of public and private organisations who have helped grow and maintain wide reach with lasting impact.
“We are calling for donations from the public, donors, partners and friends of Afrika Tikkun in the spirit of rebuilding these organisations in the aftermath of the protests. These can be monetary donations or donations in kind,” says Meulenberg. “Those who wish to extend a helping hand are urged to visit www.satownships.co.za to access our donation channels.”
The funds will come directly to Afrika Tikkun but the organisation will act only as a repository. These donations will be distributed directly to the organisations once the campaign is over, later this year. Organisations will receive monetary support or donations in kind to help rebuild their businesses.
“Most of the targeted establishments are currently not trading, meaning employees are not receiving an income. Some of the immediate needs we are tending to include food parcels and material to help them rebuild damaged infrastructure,” Meulenberg explains. The campaign is expected to run until the end of September 2021.


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Prices mentioned are inclusive of all Taxes*
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Zook Motors is planning to construct a new 48x96-foot building adjacent to its existing complex on Route 6 west of Kane.
According to information unveiled Tuesday at a meeting of the Wetmore Township Board of Supervisors, the new building will serve as a "detail shop" for the longtime business.
The supervisors endorsed the project, which now will go the McKean County Planning Commission for its approval.
In other business at the 73-minute meeting at the township building on Spring Street in East Kane, the supervisors:
*Rejected bids for the installation of a new roof on the entire township building.
The supervisors now plan to seek "phone quotes" for prices for a new roof for only the office wing of the building.
The supervisors budgeted $30,000 for a new roof, but the original bids exceeded this amount.
Gateway Estate Maintenance of Campbelltown Road near Hutchins submitted one bid of $33,400 and an optional second bid of $34,200.
Signet of Coudersport submitted one bid for $61,470 and a second proposal of $64,800.
The bids by the companies are far apart because the materials included in the proposals are vastly different.
*Agreed to utilize the services of the Jones Township Uniform Construction Code (UCC) Board of Appeals.
The UCC calls for municipalities to have a Board of Appeals. Rather than create its own, Wetmore has decided to tap the Jones Township UCC Appeals Board for services, when necessary.
*Agreed to create a Facebook account and a "simple" website on the internet.
See full article by purchasing the June 6 edition of The Kane Republican.
Board of Supervisors
When:Â Tuesday, July 2
Time:Â 7 p.m.
Where: Township Building, Spring Street, East Kane


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Paperback: 594 pages
Publisher: Nabu Press (February 20, 2012)
Product Dimensions: 7.4 x 1.2 x 9.7 inches
Format: PDF ePub djvu ebook
This is a reproduction of a book published before 1923. This book may have occasional imperfectionssuch as missing or blurred pages, poor pictures, errant marks, etc. that were either part of the original artifact,or were introduced by the scanning process. We believe this work is culturally important, and despite the imperfections,have elected to bring it back into print as part of our continuing commitment to the preservation of printed workswo...
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'It Was Something Like 9/11': Details of Deadly NYC Fire Revealed by Witnesses
19:02 GMT 10.01.2022 (Updated: 21:08 GMT 19.10.2022)
One resident of the building where the fire broke out reportedly mentioned that the fire alarm “goes off in the hallway all the time, at least twice a week,” and that people on the third, fourth, and fifth floors “went about their day until they saw smoke.”
Following a deadly fire that ravaged a high-rise in the Bronx on Sunday, claiming 19 lives and leaving 32 people wounded, witnesses shared details of this terrible tragedy with the media.
Dilenny Rodriguez, a 38-year old resident of a 9th floor apartment in the devastated building, said she heard “a lot of kids yelling, ‘Help! Help! Help!’” according to New York Post.
"It was dark. The smoke was really bad. Those kids crying for help," she said.
Another witness, a 13-year old named Alanny, told the newspaper that they “saw moms fainting” as they "saw their kids dying.”
Alanny’s 27-years old aunt Cristal Diaz who lives on the 15th floor said she was drinking coffee in the living room as the tragedy struck – she “started smelling smoke.”
"We started putting water on towels and the bottom of the door. Everything was crazy,” Diaz said. "We didn’t know what to do. We looked out the windows and saw all the dead bodies they were taking with the blankets.”
Their 65-year old neighbour Christopher Carrasquilo rushed to help, as “a little kid was stuck in the elevator.”
"I had to bring him down. It was something like 9/11," he said, with the newspaper noting that the man had tears in his eyes.
One resident, who asked not to be named, reportedly said that “the fire alarm goes off in the hallway all the time, at least twice a week,” which might have had a detrimental effect on the speed with which people reacted to the disaster.
"What do I do when I watch a movie? I put the volume up because it goes off all the time," the resident said, referring to the fire alarm. "I don’t know if it’s faulty or what it is. … People on the third, fourth, fifth and went about their day until they saw smoke."
The fire, which has already been branded the deadliest in NYC in the last three decades, killed 19 people, nine of them children; a four-year-old was among the deceased, The New York Post says citing police sources.
9 January 2022, 18:52 GMT
The blaze was apparently caused by a malfunctioning space heater in a duplex apartment spanning the second and third floors of the building.
NYC Mayor Eric Adams, who assumed office this month, has already called the fire one of the worst in NYC’s modern history.


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First, hat tip to angels134 for reminding me of this.
The first game in Fenway Park was on Apr 20, 1912, so it’s officially 108 today. It was supposed to open earlier, but the first two scheduled games were rained out. The game on Apr 20 was a 7-6 Red Sox victory over the NY Highlanders (later Yankees).
The park, as a whole, would be familiar to today’s fans except for one thing: the “Big Green Monster” was different. The wall was there alright, but it wasn’t green—it was covered in ads. In front of the wall was a 10 ft artificial hill too, which became known as Duffy’s Cliff in honor of Duffy Lewis, Red Sox outfielder 1910-1917. The hill was considered in play, but it was also standing-room-only area for spectators. Talk about your fan-Interference! The hill was removed after the 1933 season. I’ve seen one source say 1934 is when The Monster was painted green, and another that it was 1947; whatever, just glad there’s no more Duffy’s Cliff.
The Boston Red Sox won the World Series in 1912, over the NY Giants. It went to 8 games—an earlier game ended in a tie due to darkness. There are reports that a number of Red Sox (including Smokey Joe Wood) lost money betting on game 6 and recouped it by throwing game 7. My how things changed in just eight years—from no real controversy to one that is still infamous over a century later.
Fenway’s first game was also just 6 days after the sinking of the Titanic
2 thoughts on “Happy Birthday, Fenway!”
And only another 39,383 days from the sinking of the Titanic until Mookie Betts was traded to the Dodgers.
Also the anniversary of the opening the same day of deeply missed Navin Field/Briggs Stadium/Tiger Stadium.
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The Magnitude of Underinsurance in Colorado – Issue Brief
June 15, 2010
Prepared for The Colorado Trust by the Colorado Health Institute, this issue brief is based on data from the 2008-09 Colorado Household Survey (which later became the the Colorado Health Access Survey). Key findings show that 650,000 Coloradans were underinsured—almost the same number as uninsured residents—and, although individuals over 65 years old usually have Medicare, the highest rate of underinsurance occured among this age group. As well, underinsured Coloradans were more likely to forego medical care and/or report problems paying medical bills than those Coloradans deemed adequately insured.

domain: sociology