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Introduction: Running a small business in Mississauga comes with its own set of legal challenges and considerations. From initial setup to ongoing operations, having the guidance of an experienced small business lawyer can be instrumental in protecting your interests and ensuring compliance with applicable laws. In this blog post, we will explore the importance of small business lawyers in Mississauga and introduce you to Falcon Law PC, a trusted legal firm ready to assist you with all your small business legal needs.
Understanding the Role of Small Business Lawyers: Small business lawyers specialize in providing legal advice and assistance to entrepreneurs and small business owners. They offer a wide range of services tailored to the unique needs of small businesses, including business formation, contracts, intellectual property protection, employment matters, compliance, and dispute resolution.
Why Work with a Small Business Lawyer in Mississauga:
- Business Formation: Starting a small business requires careful planning and legal considerations. A small business lawyer in Mississauga can guide you through the process of selecting the right business structure (sole proprietorship, partnership, corporation, etc.) and help you with the necessary documentation and registrations.
- Contracts and Agreements: Contracts are the foundation of any business relationship. A small business lawyer can assist you in drafting, reviewing, and negotiating contracts to protect your interests, minimize risks, and ensure that all legal requirements are met.
- Intellectual Property Protection: Protecting your intellectual property, such as trademarks, copyrights, and patents, is crucial for the success of your business. A small business lawyer can help you navigate the complexities of intellectual property law, conduct trademark searches, and file the necessary applications to safeguard your valuable assets.
- Employment Matters: From hiring employees to managing workplace policies and resolving employment disputes, small business owners face various employment-related legal issues. A small business lawyer can provide guidance on employment contracts, compliance with labor laws, and assist in handling disputes or terminations.
- Regulatory Compliance: Small businesses must comply with numerous legal and regulatory requirements. A small business lawyer can help you understand and meet these obligations, ensuring that your business operates within the boundaries of the law.
Contact Falcon Law PC for Expert Guidance: When it comes to small business lawyers in Mississauga, Falcon Law PC is a trusted legal firm with a wealth of experience. Their dedicated team of small business lawyers understands the unique challenges faced by entrepreneurs and small business owners in Mississauga and can provide tailored legal solutions to protect your business.
To benefit from their expertise or to discuss your small business legal needs, contact Falcon Law PC at 1-877-892-7778 or via email at email@example.com. Their knowledgeable team is ready to provide the guidance and support you need to navigate the legal complexities of running a small business.
Conclusion: Running a small business in Mississauga requires careful attention to legal matters. Engaging the services of a small business lawyer can help you navigate the intricacies of business formation, contracts, intellectual property protection, employment matters, and regulatory compliance. Falcon Law PC is a reputable legal firm with experienced small business lawyers who can provide the necessary guidance and support to protect your business interests. Contact Falcon Law PC today to ensure the legal well-being of your small business in Mississauga.


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OK, let me begin by saying that I think this post deserves being written as a seprate entry instead of being incorporated into a general Glasgow/food/other post. We’re talking about POUTINE here – what other justification does anyone need?
So here’s the deal. I was looking up restaurants in Glasgow that serve various types of cuisine – Chinese, Japanese, Thai, Vietnamese, Belgian, and Korean, just to name a few. I know I know, so much for trying local food, right? Don’t worry, I’ll get to the haggis and the deep-fried Mars bar. Of course, I thought, I should look up some beloved food from the True North Strong and Free, and what better to represent the land of Canadia than…POUTINE! (What is poutine, you ask? To put it simply, poutine, pronounced pu-teen, is a Canadian dish of French fries with cheese curds and gravy, invented in Quebec. Let’s not try to think of the implications on health here…)
With anticipation I Googled “poutine in Glasgow”, completely ready to be disappointed. But what I found made me gasp for joy (and worry a little, for my health), for what do you know…there is indeed a place in the city centre that serves our cheese curd-topped, gravy-dripping, artery-clogging goodness. Bread Meats Bread – a clever name for a burger restaurant, isn’t it? My Canadian soul screamed, “GO TRY IT.” So I did.
The restaurant was quite busy when I arrived and I had to wait for a seat. One of the advantages of dining out alone is that you can take the odd seat instead of waiting for a proper table, which were all occupied. After about 2 minutes, the server led me over to a seat in the corner of the restaurant. It was the rightmost one in a horizontal row of three, and the two others have already been occupied, so naturally, the remaining seat would be perfect for me, a lone diner. The best part about this seat? It faced the street and I could see it right through the glass. It was a perfect time to people-watch as I waited for my food, and maybe I was being watched from the outside as well? Who knows 😛

domain: geography


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L.A. by way of RISD by way of L.A. best friendsies and pARTners Lisa Ziven and Dakota Solt reentered the city’s scene with a bang last year with their CRYBABY presents pop up art events at their La Brea storefront. For their third installment, they’ve taken over a location at Urban Outfitter’s Space 15 Twenty with similar panache. FOAM rolled by last weekend’s opening party for “Do Not Remove” and soaked in Solt’s digital collages, Ziven’s plush sculptures, a bevy of aesthetically superior commercial objects—and perhaps a beverage or two.
The show opened in conjunction with the White Iris Record Music Series and featured a live performance by local boys Princeton and a DJ set by Sean Bowie of Teams. Check the series (schedule below) and make sure to stop by the pop-up, which is open until March 29th.
February 18th: Deap Vally + DJ Neil Schield from Origami Vinyl
March 3rd: Only You (with Rachel Fannan of Sleepy Sun) + DJ Victoria Bergsman of Taken by Trees
All photos by Tiger Tiger.

domain: entertainment


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- Photo Essays
If you’ve been following this blog for a while you will know how much I love being by the sea. And hiking.
So spending my birthday weekend with a few friends by the coast hiking the Cape to Cape Track in the South West of Western Australia seemed like one of my better ideas.
Plans were made, tents were hauled out of storage, supply lists were drawn up….we were good to go!
The weather, however, had other ideas.
It’s common knowledge that there are grizzly bears in Alaska. So on a horse-riding trip in the Talkeetna mountains in Alaska it made sense to ask our guide whether there was any chance of encountering a grizzly.
“Oh they usually tend to stay away from the horses”
The only word I heard in that sentence was “usually”.


Separate names with a comma.
Discussion in 'Politics, Religion, Social Issues' started by jkcerda, Jan 3, 2014.
There will be some that browse to that article, and think it's real
The challenge of ODing on Mary Jane... 8*
This story is actually being circulated as true in some circles...
The Onion would be proud.
Happens to them about once a week. The Sarah Palin Arrives in North Korea for Mandela Memorial was brilliant.
Agreed, that was too funny!
I was going to ask, why didn't I hear about this and I live here?
Dr. Jack Shepard gave it away for me being a huge LOST fan.
Unless you're smoking like a thousand joints at once, its almost impossible to over dose on marijuana.
btw you should read the other headlines on that website: http://dailycurrant.com/
pretty funny stuff actually. Especially about the Vatican Drone Program.
For me it was the mention of the Rocky Mountain News, a newspaper that went out of business a few years ago.
Before I even entered this thread my thoughts were ....."Damn, capitalism is already poisoning weed with additives". Glad that's not the case, at least for now.
Give it time. Same thing big tobacco did to cigarettes will happen to pot.
I look forward to hearing the future story of the Jeffrey Wigand of the maurajuana industry.
My favorite to date is Michele Bachmann's campaign against falafel:
well, I managed to get 6 pages out if this one http://www.archerytalk.com/vb/showthread.php?t=2159608
That is just really great.
Stay on topic damn you. As long as the thread is about marijuana use in Colorado, this one provides a better extension.
I have been avoiding the bulk of television lately, but some of you might pick up on this reference
One of the those victims was 29-year-old Jesse Bruce Pinkman, a former methamphetamine dealer from Albuquerque who had recently moved to Boulder to establish a legal marijuana dispensary.
What is it about news sites named for produce? And why do we not have a pool going on how long it is before NewsCorp starts regurgitating this as fact?
What's sad is that this isn't any more ridiculous than some of the things she has actually said!
I don't think FOX has bitten yet but Drudge and Breitbart have.
You'll most likely die from lung cancer way before OD'ing
I o.d.'d on Nabisco Nilla Wafers once...
Thank you for this. I've posted this to troll my friends and family on Facebook the instant after I finished reading it.
"THIS IS TOTAL BS! I CAN'T BELIEVE YOU ACTUALLY BELIEVE THIS STUFF! IT'S A PARODY SITE FOR ***** SAKE"!
"No, man. It's the truth. More proof of your president Hussein Obama's socialist/mooslish agenda coming to pass. You left-wings *******s types can deny reality all you want, but it's real, and it's happening".
edit: bonus points, cuz I've now got people throwing Snopes at me!
I must be a horrible person, because that really made me laugh.
We're both horrible people.
The worst thing is, everyone I've got on Facebook should know better, but they just can't resist taking the bait. I mean it never fails...
I guess so, because I would have done the same thing if I paid any attention to facebook.
I see people post DailyCurrent articles all the time on my Facebook and then tell me I'm wrong when I tell them its a satire site.
It's usually the same idiots that post the "Obama is giving free gas to poor neighborhoods" (from Daily Currant) article over and over.
Hahahahaha this sounds just like my Facebook wall!


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Jeweled Space by Iasos, released 12 April 1987 1. The Valley of Enchimed Peace 2. The Royal Court of Goddess Vesta Designed as a subtle refined background music, to be played at low volume. The first track is cool and soothing, while the second track is warm and nurturing. Ideal for continuous-play. Includes unlimited streaming via the free Bandcamp app, plus high-quality download in MP3, FLAC and more. Purchasable with gift card.
Jeweled Space is a studio album by new-age musician Iasos. It was released on cassette by his Inter-Dimensional Music label in 1981 and then re-released in 1986, 12 April 1987 and 2008 (1986 and 1987 versions are better-known). Most of the versions include two equally 30-minutes long tracks, "The Valley Of Enchimed Peace" and "The Royal Court Of The Goddess Vesta" (on some versions lengths vary). They are ambient, drone-like electronic new-age pieces
Iasos (born 1947 in Greece), an American resident since 1951, he is a new age musician living in the San Francisco Bay Area of California. He is one of the earliest creators of the "new age" genre. His company, Inter-Dimensional Music, is based in Sausalito, California. Jeweled Space 1987, Inter-Dimensional Music (BMI: Galaxia Creations). Essence of Spring 1989, Inter-Dimensional Music (BMI: Galaxia Creations). Bora Bora, Inter-Dimensional Music (BMI: Galaxia Creations). Iasos – Celestial Soul Portrait 2013, Numero Group. Essence of Lemuria 2015, Inter-Dimensional Music (BMI: Galaxia Creations).
Album · 1986 · 2 Songs. See All. Spectrum Suite (Bonus Version) . 1975. They are ambient, drone-like electronic new-age pieces
Iasos - The Royal Court of Goddess Vesta. Please support the artist and purchase the single/album directly from Bandcamp. com and adhere to our Terms of Service.
|1||The Valley Of Enchimed Peace||30:00|
|2||The Royal Court Of Goddess Vesta||30:00|
NotesAvailable from the artist: www.iasos.com
|VE6-C||Iasos||Jeweled Space (Cass, Album)||Inter-Dimensional Music||VE6-C||US||1981|
|none||Iasos||Jeweled Space (Cass)||Inter-Dimensional Music||none||US||1986|

domain: artistic


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Lynn and Susan parsed the Supreme Court decision overturning the Colorado Supreme Court's decision to keep Trump off the ballot for being an insurrectionist and noted that while the initial part of the decision was unanimous, other parts broke down by gender not political affiliation. Also, they talked about how restrictive America is for women and noted how the French just overwhelmingly amended their constitution to give women full control of their bodies and how Mexico is poised to elect a Jewish woman president, two things unthinkable in the good old USA. And on a less important matter, how men are going to plastic surgeons to have their nipples made smaller and almond-shaped like David Beckham's.
Audio Only Archive
Stream or download the last 5 shows on the MP3 downloads page.

domain: law


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Quiet and private 5 minutes walk rail, shopsLindfield Cottage 5 mins walk (470 metres) rail Stn, restaurants, newly opened Harris Farm market, bakery, new supermarket. Very Quiet and private. Air con, heating, free Wifi, DVD, coffee machine, Nth facing deck overlooking fishpond and landscaped gardens, outdoor seating. Two burner cooktop, microwave, fridge, toaster ect. Ensuite, parking on the street at all times. White towels/ linen provided, quality queen size bed . Leather settee Entire place with privacy. Landlord pays for cleaning
River view, Resort style accommodationSparkling clean and sanitised, wake up to stunning river views, enjoy breakfast on the sun drenched balcony or take a trip on the Rivercat ferry to Circular Quay and the Sydney CBD.
Cozy studio - Private and convenientA private stay in a newly renovated studio located in a quiet neighbourhood. Fully detached from the main house. The studio and its items are for your private use. A 5-minute drive to Parramatta CBD (30 mins train to Sydney CBD) and walking distance to Westmead children's hospital. Couples, professionals, adventurers and business travellers are very welcome. Hungry Jacks, KFC and 24hrs McDonalds are within walking distance. If you use public transport the nearest bus stop is 1km away.

domain: travel


Nous avons le plaisir de vous inviter à une discussion avec Yehuda Shaul et Hugh Lovatt sur le thème : « The future of Israeli-Palestinian conflict: towards annexation and illiberalism? »
Israel / Palestine
Discussion of the US 'peace' plan for the Israeli-Palestinian conflict and EU's position and role in the peace process
The United States is set to propose an economic plan for Israel-Palestine, spearheaded by Jared Kushner, on 25 and 26 June in Bahrain, where Gulf Arab states will discuss the troubled Palestinian economy
A quarter of a century on from the Oslo Peace Accords, young Palestinian writers share their views on the future of the two-state solution
An open letter by high-ranking former European Union officials urges Europe to reject a United States Middle East plan in the case that it promotes unequal rights between Israel and the occupied Palestinian territories. A number of ECFR Council Members have signed it.
Amidst allegations of fraud and bribery, Israeli PM Netanyahu has called for a snap election on 9 April. In what direction could a new Israeli government take its foreign policy?
Introduction War threatens to engulf Gaza’s fragile calm. In each of the three recent conflicts that have shaken the Gaza Strip, fighting between Palestinian factions…
To take stock of the recent escalation in Gaza and international stabilisation efforts
With Seth Anziska, University College London Moderated by Hugh Lovatt, ECFR Policy Fellow Thursday 11 October, 12.30-13.30 (registration from 12.15) ECFR, 4th floor, Tennyson House, 159-165 Great Portland St, London W1W 5PA
This summer, Ibrahim Boubacar Keita was re-elected to Mali's presidency; his plan for peace in the country can stem the conflict, but as the Algerian case shows, the process of reconciliation can be daunting


The Continental Continental Gator Hardshell Folding Road Cycling Tire is ideal when it comes to extremely long service life, for the next tour, or the commute.
Made for for rough surfaces and rugged tarmac.
The Gatorskin has set the bar for a perfectly balanced blend of ride quality and long term durability, all without breaking the bank.
POLYXBREAKER- The polyester fibers overlap during manufacturing, yielding a very dense fabric and minimal space in-between threads, making the PolyX highly resistant to any foreign body without reducing the rolling resistance.
DURASKIN- Sidewall protection coming from the high quality polyamide fabric encasing the core casing of the tire from scuffs and cuts under the worst conditions.
Hardshell protection is comprised of three main components, a deep casing overlap providing added sidewall protection, and extra wide PolyX breaker protecting the entire tread strip and finally, the casing is sheltered by a bead to bead layer of DuraSkin fabric.
HANDMADE IN GERMANY-Continental has been hand making their tires since 1871, maintaining the integrity of tradition, while evolving with the most advanced technology.


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- College of Medicine Students
During their first week of medical school, the College of Medicine’s first-year M.D. students conquered a scrubs relay race and water balloon toss, received iPads for interactive learning and joined student interest groups for specialties such as pediatrics, academic medicine and women’s studies. And now it’s class time.
After August 6’s traditional White Coat Ceremony, 100 new M.D. students were welcomed to the UCF Health Sciences Campus. During the Orientation Fair, they met faculty members, received a wrapped gift of a new iPad from the Harriet F. Ginsburg Health Sciences Library staff and signed up for college’s award-winning chapter of the American Medical Student Association.
Faculty, staff and students gathered for a pot-luck All-College celebration. And M-1s and their “big sibs” competed on the Tavistock Green in a Greek field competition. Each student is part of a four-class family named after a Greek god or goddess. Students dressed in costumes – including face paint – to symbolize their Greek families. This year’s winner: The Aphrodite Family. (Special thanks to ace photographer Alex Chacon who kept up with the two-hour test of endurance and even judged some of the competitions.)
With the addition of the class of 2016, the College of Medicine’s enrollment is now 280, a seven-fold increase in just four years.

domain: news


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Dogs banned from school playground over health and safety concerns
Dogs have been banned from a city primary school amid health and safety concerns.
A small number of 'irresponsible dog owners' have forced senior staff at Dore Primary School, in Dore, to ban the animals from school grounds.
They claim children are being left 'distressed' after stepping in dog dirt in the playground, while parents have raised concerns about that youngsters could be bitten.
Parents and carers have received a letter from the school informing them of the new policy on dogs.
The letter states that a number of complaints have been received from parents indicating that many are finding 'the presence of dogs in the playground, stressful, even frightening, particularly for younger children' and that the playground was not an acceptable place for the animals.
Governors and staff have also raised concerns over the amount of dog fouling in the playground, which staff are forced to clean up.
People are also banned from tying up dogs and leaving them unattended at the school gates or on fences around the premises.
Speaking on behalf of staff and governors, headteacher Lynnette Glossop, said: "We have received a number of complaints from parents after a small minority of irresponsible dog owners allowed their dogs to foul on school premises.
“As children’s health is our utmost priority, we sent emails out to parents asking them to clean up after their pets. Sadly, the problem persisted, and several children have become very distressed after stepping in dog excrement. Staff also had to regularly clear up the mess.
“We also had other complaints from parents and carers around the sheer numbers of dogs in and around school. Even well-behaved dogs can behave unpredictably in busy and crowded environments. We want to avoid placing any children in a position where they could be bitten."
“In October last year we began monitoring the situation as regards the dog dirt and, as it was not improving, governors decided that they were minded to ask parents not to bring their dogs onto school property. This is in line with many other schools across Sheffield.
“A meeting with parents and carers was then held in January - where many whom were dog owners – told us they were strongly in favour of not having dogs at school. The decision was then made, and implemented following agreement at the most recent governors meeting."
“We recognise that dogs are an important part of many people’s lives. We at Dore Primary School are dog lovers too, and it is a shame that a small number of people who show a disregard for the health and safety of their own children and others have forced us to implement this new rule.”

domain: sociology


Often, it's more than the Parks & Recreation staff of 30 can handle. For that, there's the Adopt-a-Park Program.
One St. Joseph man has taken it to heart.
When Tim Doyle goes to St. Joseph's Riverfront Park, he sees the trash, the graffiti and the wear and tear of time and neglect. But, he also sees potential.
"There's so much that can be done here," Doyle says.
Doyle has vision.
"I would love to see events happen down here," he said. "I would love to see concerts in the summertime. Different events where folks can just come and enjoy, hang out and feel safe."
Doyle admits before the park gets to that point, much work needs to be done.
"I always like to bring visitors down here to show them our city's historical treasure," he said. "In recent years, it's been kind of an embarrassment."
Wanting to do something about it, Doyle created a non-profit organization and signed up for the city's Adopt-a-Park program.
For the city's more than 40 parks and 26 miles of parkway, volunteer groups agree to clean up trash in their adopted area at least once every three months. Doyle wants to focus on the riverfront.
"Things have fallen into neglect," he said. "I understand the city's resources are tight. We felt like as a citizen's group, if we could step up and help."
Parks & Recreation staff agree. Civic and other volunteer groups volunteer as much as $92,000 in manpower per year.
"It really makes a difference to have help," said Lucinda Weaver, a layout and design technician with the St. Joseph Parks & Recreation Department.
Weaver is excited that Doyle wants to go above and beyond. Through a combination of cleaning, painting, landscaping and other hard work, Doyle believes Riverfront Park can return to a place that people can be proud of.
"We believe the river is our city's greatest historic treasure," Doyle said. "I believe so much history has passed over this river, including the Pony Express. No other city in America can boast that we were the gateway for the largest human migration in history."
"To have our parks looking clean, especially that Riverfront Park looking spiffy, that's just fantastic," Weaver said.
Doyle plans a group clean-up event for this Saturday at 10 a.m.
To learn more about participating, email Doyle at email@example.com.
Copyright 2016 Nexstar Broadcasting, Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.


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Well you KNOW we want to hear about it! Reblog this post with a line about what you’re reading this week, and you’ll be automatically entered to win wonderful books and prizes.
This week’s giveaways include 20 book cover t-shirts from Out of Print clothing!
Just started “Middlesex” by Jeffrey Eugenides. It’s a family saga but focuses on gender issues as a young baby girl (Calliope) becomes a man, Cal, later in life.

domain: literature


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Sinbad UK Release Date
The movie Sinbad upcoming Blu-ray, Cinema, DVD and VOD release date in the UK is to be announced.
Release DatesReport Date / Submit Product
Report Date / Submit Product
Show Full List
The story chronicles the travels of a fictional sailor who made seven voyages encountering magical and supernatural beings.


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Adding to that opportunity, Gallup said, is the fact that only 6% of the global population has a health club membership. Instead of focusing on the low percentage, Gallup said he’s excited by the 94% of the population that health clubs have yet to reach
“Our business could grow tremendously,” he said. “But we have to inspire everybody to get in there and make sure that it’s fun and that we get results for our members.”
Focusing on Emerging Markets
Next, Gallup put the spotlight on emerging markets, listing countries with the largest percentage growth in gym members in 2018. The Philippines (+33%), China (+30%), and Finland (+25%) took the top three spots, with India coming in 10th with a 10% growth.
The 2019 IHRSA Global Report and other IHRSA research publications provide more insight into these findings.
Based on data gathered in the IHRSA Greater China Report, the combined revenue from the top 10 cities ranks fourth among all global markets at US$3.9 billion in annual revenue, while the number of club members ranks ninth in the world at 4.5 million. The IHRSA Indian Health Club Report ranks fifth in market size among Asia-Pacific health club markets at $821 million in annual revenue (USD). The number of health club locations ranks third in the region at 3,813 sites, while the country’s 2 million members ranks fifth among observed markets.
Opportunities for growth remain in both markets as well as the Asia-Pacific region, overall. The member penetration rate for China and India are 2.98% and 0.15%, respectively.


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A census and audit conducted by the Kuala Lumpur City Hall (DBKL) showed that almost 20% of the occupants of Public Housing (PA) and People’s Housing Projects (PPR) have lost their eligibility to stay in such houses.
Deputy Federal Territories Minister Datuk Seri Dr Santhara Kumar explained that the main criteria for PA/PPR occupants “to lose their eligibility is when they have other houses and with high income that they can afford to buy luxury cars”.
“However, those with high income, but have many dependents, DBKL is considerate and still allows them to continue living at the PA/PPR units,” he said as quoted by Bernama.
He made the statement after giving out offer letters to 20 recipients of PA/PPR housing units.
PA/PPR housing occupants who are no longer eligible for the homes should leave to enable those who are deserving to benefit from it, said Santhara.
On the PA/PPR housing applications, he revealed that DBKL has so far approved 2,000 out of the 30,000 applications.
Read our helpful Guides to learn all about the various property buying, selling and renting tips!


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Guinness Nigeria Plc in its FY 2019 financial report announced an 8.0% y/y decline in Revenue to N131.5 billion in FY 2019 from N143.0 billion in FY 2018. Reported Revenue of N131.5 billion came in below our FY 2019 estimate of N136.2 billion. On a q/q basis, Revenue also dipped albeit steeper, recording a 10.4% q/q decline to N30.1 billion in Q3 2019.
The decline in Revenue came as volumes, particularly in the lager segment, significantly remained pressured in FY 2019. Meanwhile, sustained growth in Spirits has helped to cushion the impact of the declines in other business segments.
Cost of Sales maintained a downward trend within the quarter as well as on a y/y basis largely due to lower volumes. Cost of Sales adjusted for depreciation declined 4.1% y/y to N84.1 billion for FY 2019 from N87.7 billion in FY 2018 and dipped 6.0% q/q to N19.6 billion. The slower decline in Cost of Sales relative to Revenue indicates some cost pressures in FY 2019.
We believe elevated barley prices, a key input for Guinness must have impact costs. Against this backdrop, Gross Profit dipped 14.2% y/y to N47.4 billion in FY 2019 from N55.3 billion in FY 2018. Operating Expenses (adjusted for depreciation) also declined, down 12.5% y/y to N29.2 billion in FY 2019 from N33.3 billion in FY 2019 due to lower Marketing & Distribution Expenses (down 18.3% y/y to N19.8 billion).
Despite lower operating costs, EBITDA slipped lower by 15.8% y/y to N19.1 billion in FY 2019 from N22.6 billion in FY 2018. Depreciation & Amortisation climbed higher by 9.3% y/y while Net Finance cost declined 45.9% y/y to N1.9 billion. Profit before tax declined 28.6% y/y to N7.1 billion in FY 2019 from N9.9 billion in FY 2018. Despite the lower tax, Net Income slid lower by 18.4% y/y to N5.5 billion in FY 2019 from N6.7 billion in FY 2018. Earnings per Share printed at N2.50/s which was in line with our FY 2019e of N2.46/s.
We have a target price of N67.90 for Nigerian breweries with a HOLD recommendation on the stock. Our model is under review for the new numbers. Current price: N41.40/s.


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Norma Thomson and Dy-Ann Simmons, had both worked-out in Bermuda's gyms for years and felt something was missing: support for people trying to lose weight. As these fitness fanatics began talking, the idea for a resort offering a holistic approach to weight-loss was born. With Dy-Ann providing the inspirational guide and Norma funneling her passion for healthy living, Fitness Bay Resort was born in Bermuda's premier resort, Cambridge Beaches. This is high-energy, holistic fitness programme is perfect for the bride-to-be who wants to shed a few pounds and buff her body ready for the big day.
BRIDAL BOOT CAMP TIP #2 Weekly tips and advice from the experts at Fitness Bay Resort
BRIDAL BOOT CAMP TIP #2
Weekly tips and advice from the experts at Fitness Bay Resort
#1 - Push ups: Will help to tone your arms, chest and core.
Place hands shoulder-width apart either on the ground or on a bench. Have your knees on ground back far enough so that your body is straight. Begin doing your push ups, 15 repetitions and repeat 3 times
#2 - Lunges: Helps to tone the butt and legs.
Alternating legs while stepping out into a lunge position and back to centre. Complete 20 repetitions of this 3 times
#3 - Crunches: Toning your abdominals.
Lay on your back with your feet flat on the ground, knees bent. Hold hands by your ears and crunch up lifting from your shoulders. Complete 20 -25 repetitions and repeat 3 times
Bonus Tip - Working Out to Relieve Stress
Stress is common when planning a wedding and there is no better way to relieve that stress then working out. The best workouts for this are walking or jogging with your iPod. Music is also a stress reliever and helps to keep you motivated while working out. Also if you are the kind of person that enjoys classes the most recomended classes are Zumba and Body Combat. They allow you to release that tension you may have through your body while having fun and getting a great workout!
Owner of Fitness Bay Resort, Norma Thomson

domain: health


Get on with it. And if you want to stand out in these times, offer a surprise to boot. That is the message from three very different central banks in a trio of equally divergent Asia-Pacific economies.
The authorities in India, New Zealand and Thailand all cut interest rates earlier this week. Each defied consensus in its own way: the first two with the magnitude of reductions, the third by cutting at all.
We have been experiencing some problems with subscriber log-ins and apologise for the inconvenience caused. Until we resolve the issues, subscribers need not log in to access ST Digital articles. But a log-in is still required for our PDFs.


We may not offer the lowest price, but we offer the best price. Tianjin Sure Instrument Co.,Ltd. regularly reviews the pricing matrix to ensure it meets the most competitive industry requirements. We offer products with competitive price levels and superior quality, distinguishing Sure Instrument brand from other coriolis mass flow meter brands.
Sure Instrument has been centering on producing high quality Pressure Transmitter. swirl flow meter is one of Sure Instrument's multiple product series. our company coriolis mass flow meter is produced strictly according to the standards in furniture manufacturing. The product has been tested officially and passed the domestic certifications of CQC, CTC, QB. With a smart structure design, no debris will be left in it. This product is unlikely to pilling. The singeing process removes and burns off any surface hair or surface fibers. It won't be affected by any factors like high temperature, pressure, density, viscosity, etc.
It is the lifelong pursuit of every our company person to build the company into the No. 1 natural gas flow meter brand. Inquire online!


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The LSU Tigers are No. 1 in the Associated Press Top 25 poll.
LSU moved from No. 2 last week to No. 1 in the poll released Sunday afternoon after Saturday’s 23-20 victory over then No. 9 Auburn. Auburn fell just two spots to No. 11.
It was the Tigers’ third victory over a top-10 team this season.
LSU is off this Saturday. The Tigers (8-0, 4-0 SEC) face No. 2 Alabama (8-0, 5-0), last week’s No. 1, on Nov. 9 at 2:30 p.m. in Tuscaloosa, Ala. (CBS).
Alabama, which is also off this week, remained No. 1 in the Amway Coaches Poll with LSU at No. 2.
LSU received 17 first-place votes in the AP poll to 21 for Alabama. The Tigers amassed 1,746 points, just two more than Alabama and eight more than No. 3 Ohio State (8-0), which also received 17 first-place votes.
No. 4 Clemson (8-0) received seven first-place votes.
Alabama received 40 first-place votes and 1,593 points in the Amway Coaches Poll. LSU received seven first-place votes and 1,515 points.
No. 3 Clemson received 10 first-place votes and 1,508 points. No. 4 Ohio State did not receive a first-place vote.


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LCTL Master Calendar
18 matches found
The Fall symposium will focus on 1917 in its immediate context and also, reflect on the broadest implications of 1917 and a century of protest and revolution.
The 1917/2017 Fall Symposium
Screening of the film "I am Cuba."
Film screening accompanied by introduction and post-film discussion.
Conversations on Europe Videoconference: "European Integration through Study Abroad? 30 years of the Erasmus Program" with multiple presenters.
This event will feature a screening and discussion of the 2014 film "The Return."

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A NEW campaign to demonstrate how superfast broadband is changing people’s lives was launched on Monday (Oct 23) in Ceredigion.
The superfast broadband campaign, run by the Welsh Government, is aiming to promote superfast broadband to Ceredigion residents to demonstrate its benefits and encourage its further use across the county.
With the majority of Ceredigion residents now having the ability to access the service, the campaign will showcase how superfast broadband is transforming the way people work, learn and connect with their families and friends.
Superfast broadband enables multiple devices to work simultaneously, allowing people to stream films, download music, study or keep in touch with loved ones without disrupting a connection.
The campaign will highlight how the service is transforming the ways in which people live and work across Wales.
Campaign organisers will be working with libraries, schools and community centres in Ceredigion and attending the Aberystwyth Farmers Market on Sunday 4 November and Llanerchaeron Christmas Fair on Sunday, December 3, to raise awareness of superfast broadband.
While most of the county can now access faster broadband should they wish to do so, a small percentage of premises are not yet able to access it. Assistance is also available for them on the Welsh Government website or by contacting the Welsh Government broadband team.
Welsh Government Minister for Skills and Science, Julie James, said: “Superfast broadband has become crucial for homes, which is why we are committed to bringing faster internet speeds to regions across Wales. Improving our digital infrastructure is key to driving economic growth, supporting public services and helping people communicate.
“While the majority of homes in Ceredigion can now access superfast broadband should they wish to, many people are simply not fully aware of its benefits or how it can be accessed. Faster broadband speeds are enabling families and individuals to carry out their activities with greater speed and efficiency than ever before, and on multiple devices. This includes activities such as downloading large learning resources for children, managing bank accounts, shopping for groceries, paying household bills or using video services such as Skype – to name a few.
“For home-workers, the service increases efficiency, boosts productivity and optimises delivery. Being able to communicate via high definition video conferencing or Skype enables companies to speak with staff, customers and suppliers from anywhere in the world.
“Superfast broadband also gives access to cloud computing services such as instant data back-ups, making security and upgrades much easier for users.
“We want as many people as possible to realise these benefits, and this campaign aims to showcase how the technology is impacting thousands of lives in communities across Wales.
“The rollout of superfast broadband is continuing across Wales and while most premises can now receive it, I know that there are premises waiting for it, or unsure as yet if they will receive it. Advice and assistance is also available for them.”
Households and businesses in Ceredigion wanting to take advantage of the benefits of fast fibre broadband should contact an internet service provider (ISP) of their choice to place an order.
To find out what broadband is available, people are advised to visit www.gov.wales/broadband
This also includes information for those not yet able to receive superfast broadband as support may be available through the Welsh Government’s Access Broadband Cymru scheme, which provides grant funding to access superfast broadband through other means.
Completing the Census will help improve the county’s services
As Census Day approaches, everyone is reminded of the benefits of taking part in this once every ten years survey.
The Census gives an accurate picture of the population and the needs of the people in the county, and affects the funding that is allocated to Ceredigion from Welsh Government annually and therefore the funding that’s available to provide critical services in the county. As a result, it is vitally important for everyone to take part in this year’s survey.
Every household in the county will receive a Census Pack in the coming weeks, which will include either a letter with a unique access code for online completion or a paper questionnaire. The Census Packs will include instructions on how to complete the questionnaire.
The last Census, which was held in 2011, showed that 75,922 people lived in Ceredigion, including 11,318 students. The most popular occupation for the county’s residents was farming, with 2,063 people identifying themselves as farmers, and 676 people noted they were nurses.
Data from Census 2011 supported the identification of Ceredigion (and three other local authorities in Wales) as target areas for the £2 million Arfor Innovation Fund Scheme.The data highlighted Ceredigion as a suitable area for the scheme, due to the county’s high proportion of Welsh speakers, and inflow of older people and outflow of younger people. Consequently, almost £500,000 has been made available by the Welsh Government to Ceredigion, to support Welsh language businesses and entrepreneurs in the area.
In addition to this, the data collated during Census 2011 helped to develop play and recreation areas at Llanddewi Brefi, Llanon, Ponterwyd and Cardigan. By using this data, it was possible to apply to the Welsh Government Rural Communities Development Fund (RCDF) and show how much these services are needed by local residents.
Information gathered as part of the Census enables local and national governments to plan services for various sectors, including healthcare, social care, schools and transport.
Councillor Ellen ap Gwynn, Leader of Ceredigion County Council, said: “Not only is the Census fascinating, but it also gives the best possible estimate of our population today. Over the years, we have been able to use this data to plan services, by tackling and prioritising the needs of our communities in Ceredigion. I urge everyone to complete this mandatory survey in order to gain a true picture of the county’s fabric. Who knows what the data from Census 2021 will bring? But one thing is certain, taking part will benefit the residents of our county.”
Census Day will be on 21 March 2021, but households will soon receive Census Packs in the post explaining how they can take part. The Census will include questions about your sex, age, work, health, education, household size and ethnicity. And, for the first time, there will be a question asking people whether they have served in the armed forces, as well as voluntary questions for those aged 16 and over on sexual orientation and gender identity.
In Wales, households will also be asked a specific question about their Welsh language skills. And those who wish to complete the Census in Welsh can do so both online and in paper form.
Because these things matter to us all, everyone needs to complete the Census. The Office for National Statistics (ONS) runs the Census in England and Wales and is independent from government. Your details are protected by law and information published is always anonymous.
For more information and to find out how you can access help, go to www.census.gov.uk or call the contact Centre on 0800 169 2021.
Elin Jones backs calls for business rates holiday extension for independent businesses
CEREDIGION’S Member of the Senedd, Elin Jones, has backed calls by the British Independent Retail Association for the extension of the current rates holiday for non-essential businesses in 2021/22.
Many local independent businesses have been closed for the best part of a year, and many will be in a more precarious situation now than when the initial rates holiday was announced last year. Many businesses will be looking forward to the easing of restrictions over the next few months, but Elin Jones warned that many would benefit from the continued business rates holiday.
Elin Jones said:
“Every effort must be made to secure the future of independent businesses in Ceredigion. They are such an important feature of life in Ceredigion, both as employers, and as a draw for people to our towns and villages.
“Normal trading will eventually resume, and these businesses will be able to flourish again, but local businesses owners know that this cannot be rushed. Therefore we must continue to sustain our businesses until they are once again back on an even keel.
“It will take a while for footfall to resume, and extending the business rates holiday is one way to help in this time of need.”
MP makes Budget case for support for self-employed and small businesses in Ceredigion
BEN LAKE MP has called on Chancellor Rishi Sunak to extend the government’s financial support package for businesses and self-employed workers in next week’s Budget as many struggle to stay afloat during continued lockdown restrictions.
The Chancellor, Rishi Sunak is to set out the UK Government’s budget on Wednesday 3 March, almost a year since the last Budget on 11 March 2020.
To help businesses and our local high streets over coming months, the Ceredigion MP has called on the Chancellor to extend the lowered rate of VAT at 5% for hospitality and tourism for a year to March 2022 and to extend the business rates relief package.
Mr Lake also called on the Chancellor to retain the furlough scheme for the duration of pandemic restrictions, as recent figures show more than 178,000* in Wales are still receiving government help from the CJRS. He also urged the Chancellor to expand the existing eligibility criteria for the Self-Employed Income Support Scheme in order to offer some help to the many individuals who have not received a penny in Government support thus far.
Ben Lake MP said: “For many businesses and self-employed workers, the financial support government has offered over the last 12 months has been a lifeline. Now, as we are finally starting to see light at the end of the lockdown tunnel, we cannot remove this lifeline prematurely. Extending this help for a little longer, and expanding the criteria to help those that have been excluded thus far, would offer small businesses the support they require to ‘bounce back’ from the pandemic.”
Many businesses who are still not open due to lockdown measures are also now expected to start repaying their Bounce Back Loans. This is despite their situation largely remaining unchanged since they took out the loan, or in some unfortunate instances, worsened as they have not yet been able to trade.
UKHospitality has estimated that the hospitality sector lost around £72 billion in sales in 2020 and faces, frankly, a debt mountain, including £4.2 billion in state-backed loans.
Mr Lake said: “It is important that businesses that took out bounce back loans and CBILS are required to pay only when they are in a position to do so – once they have ‘bounced back’ from the pandemic. Affording such a level of flexibility, and thus preventing avoidable business failures, would protect jobs, the taxpayer’s investment in the recovery, and the integrity of our financial system.
“We remain in the early stages of a vaccine-led recovery, and it is likely that we will have some form of restrictions for many months to come. Having done so much to protect the economy and the workforce, we must not withdraw support prematurely, as to do so would risk throwing away the investment taxpayers have made in the last year, and potentially our economic recovery.”
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- This event has passed.
2015 BCLC Midsummer Music Jam
July 23, 2015 @ 7:00 pm - 8:30 pmFree
Join us as we celebrate 30 years in Kamloops with the BCLC Midsummer Music Jam hosted by Mark Madryga and with musical guest, Catch 22.
Stop by for great entertainment, free ice-cream and hundreds of prizes! Bring a donation to help support the Kamloops Food Bank.
All concerts are “rain or shine” and are subject to change.


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Book Luxury Hotels in Bangalore
(58 Hotels in Bangalore)
Great food, especially very good staff, very homely atmosphere. Better than a five star . . Recommend this for everyone, although its booked throughout the year, have to book in advance. Centrally located, serene environment. Will try and stay in this place every time I am in Bangalore
anand surapur | Mon, May 14, '18
Rs. 7,317Choose Dates
This is our 5th Visit to Our Native Village and my experience with the resort is quite satisfactory, except for a few hitches This is a very nice resort which has all the requirements, that of a village. You would feel that you are in a village. First, this is a pet friendly resort and the primary reason why we come here is for our pet. Our pet enjoys every bit of the time that we spend here There are a few areas that needs attention:. 1. The rooms are not clean and there are dust and the webs all over the room. 2. The cots and the wardrobes are broken and needs to be fixed, basically all the rooms require a revamp 3. We pay around 10k per room and would definitely like to have lot of other needs, such as a lot more toiletries, intercom and laundry facilities. 4. Though the food is tasty, the options are very limited. You don't have a choice at all regarding the selection of food. I would really look forward to having a good and wide spread of food when we next visit the resort Overall, I would rate the resort 3. 5 stars .
Srinivas | Sun, Apr 29, '18
Room, space, furniture, amenities, balcony, were all superb. Food and service was commendable. Has only a veg restaurant but they had provided in room, phone numbers of restaurants nearby with menu cards so we could order and get delivered. Pool was clean and good to use.
Michael Ponnudurai Samuel | Mon, Apr 16, '18
Rs. 6,999Choose Dates
People are really good, but the hotel lacks in some amenities which other hotels have like tea maker in the room etc.
Utkarsh Singh | Fri, May 18, '18
Rs. 9,000Choose Dates
Great place for the price I got it for . Thanks to the ongoing deals at MMT . It's in the heart of the main area but still location wise it is away from all the hustle . A short walk into a lane, might make you wonder what would lie inside, but once you are in front of the building, it rather looks like home . Small reception, spacious room, beautiful terrace with greens and plantation that makes morning & evening sitting pleasant . Surprisingly, for a small space, breakfast buffet was well spread . It just felt like home, not a hotel.
Rahul Mehta | Sun, Mar 11, '18
Rs. 7,317Choose Dates
Overall it was pleasant experience, good for weekend escapes. Even though food is expensive. Single biryani 550-600 rupees + taxes for room service. Lunch/Dinner Buffet was 1250 (including taxes) per person Not much starter option for Non-Veg / Veg. Rooms are OK. These things can be improved. Good for day out rather than night stay.
AKHIL CS | Sun, Mar 18, '18
Rs. 8,925Choose Dates
Very good room (was lucky to get an upgrade to a junior suite! ). Extremely friendly and courteous staff which goes that extra mile to ensure your comfort. The location is a bit away from the city center but the great service more than makes up for that disadvantage. Definitely will come back again
Dhaval Dalal | Wed, May 2, '18
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Palestinian groups have until now generally fired three versions of Qassams, improvised steel rockets filled with explosives and fuel. They can travel between one and five miles. Qassam-3’s travel the farthest and are the largest, at about four feet in length. The rockets lack a guidance system and are launched from Gaza towns by terrorists who reportedly use the rocket’s trajectory and known travel distance to aim at Jewish neighborhoods near the Gaza border. About 20 percent of Qassams do not explode upon impact.
The imported missiles, Katyushas, are better guided, travel farther and cause more damage because they have a warhead of up to 20 kilograms, roughly the weight of a cannon shell from one of Israel’s Merkava tanks.
Hamas has fired at least 5,500 rockets since seizing Gaza in 2007
It’s not “too small” problem. It’s wrong-tool-for-that-task problem. Patriot is designed as costly, sophisticated air defense system launching Mach5, 5 meter long, millions-of-dollar missiles. Hamas “missiles” are mostly hand-made Quassam rockets, 2 meter long, with twenty kg of payload, and costing some hundred dollars and a bottle of moonshine each. Even if Patriot were capable of intercepting them, it’s kinda like using anti-tank rocket launcher for destroying some militant on bicycle.
ETA: By “Katyusha” you probably think Grad artillery rockets. They are unguided, but more accurate than Quassam. Not larger than Quassam-3 though.
That is inaccurate. The Patriot system was designed to kill aircraft. It does that better than any other system in the world except for our Aegis system (which sometimes uses the pac-3 missile anyway).
The mission to kill ballistic missiles was a new one for the Patriot. The pac-2 missiles were almost untested against real ballistic missile threats, and not against missiles as large as scuds. There aren’t really any portable and highly effective ABM missile systems to compare patriot against anyway.
The modern pac-3 missiles are far more effective against ballistic missiles in tests so far by multiple countries.
Calling the patriot system a piece of shit is akin to calling the A-10 a failure because loading them with sidewinders and having them intercept mig-29s isn’t incredibly effective. But when they are all you have, it’s worth a try.
Also, I’ve read somewhere that the Scuds used in the first Gulf War were so old and badly rusted that they would break into several pieces upon descent. That made interception extremely difficult.
Eventually Patriot crews found that the pieces containing the warheads would follow a more stable trajectory and manually aimed at those pieces only. This practice somewhat increased the interception success rate.
Ballistic missiles travel in a ballistic arc (mostly). Unless you turn the missile into really small pieces, a missile in terminal phase is going to come down in the same general area as the target. “Populated areas” aren’t point targets. This, combined with the difficulty of fully neutralizing a warhead, makes ABM duties very tough.
RE: guidance – the missile isn’t in powered flight the whole way, but it can still have terminal guidance, just like laser guided bombs. If it didn’t, small vagaries in air resistance or wind would make the missile a lot less accurate.
I pretty sure the IDF has developed a laser-based missile defense system possibly capable of tracking and destroying rockets. The system has not been deployed due to a combination of factors - toxic waste being one problem (chemical laser), debris showers being another (the difference between an exploding rocket and a falling one is not always that great).
And given the current ease of deployment of the rockets, any defense system can be overwhelmed by sufficient multiple launches.
And while the current British naval point defense missile system can hit “a cricket ball travelling at mach 4” (quoted by a current naval weapons rating, a family friend who was visiting for christmas, and which sounds more like a marketing quote than a technical specification to me), the cost per launch would be so excessive that a few days defense would eat up the entire IDF budget without hitting the source.


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CASE REPORT article
Sec. Cardiovascular Imaging
Late-Stage Löffler's Endocarditis Mimicking Cardiac Tumor: A Case Report
- 1Department of Cardiology, Shonan Fujisawa Tokushukai Hospital, Kanagawa, Japan
- 2Department of Cardiovascular Medicine, Narita-Tomisato Tokushukai Hospital, Chiba, Japan
- 3Department of Pathology, National Cerebral and Cardiovascular Center, Suita, Japan
- 4Department of Radiology, Asahi General Hospital, Asahi, Japan
- 5Department of Cardiovascular Surgery, IMS Katsushika Heart Center, Tokyo, Japan
Löffler's endocarditis (cardiac involvement in hypereosinophilic syndrome) is rare yet life-threatening if left untreated. We describe a case of hypereosinophilic syndrome presenting as a cardiac mass with an abnormal electrocardiogram. Diagnostic studies of the cardiac mass strongly suggested a malignant cardiac tumor invading the papillary muscle. Thus, excision of the cardiac mass and endomyocardial resection with mitral valve replacement were successfully performed. Pathology revealed various stages of thrombosis and irreversible myocardial damage caused by eosinophilic infiltration with no malignancy, leading to the correct diagnosis of late-stage Löffler's endocarditis. The subsequent combination of anticoagulation and corticosteroids was effective with a favorable outcome. This case highlights pitfalls in multimodality imaging of cardiac thrombus and the clinical significance of considering Löffler's endocarditis in the diagnostic work-up of a cardiac mass.
Hypereosinophilic syndrome (HES) is an uncommon group of diseases characterized by persistent hypereosinophilia with eosinophil-mediated multiple organ involvement (1). Diagnosis of HES is based upon the following criteria; an absolute eosinophil count >1,500 cells/μL in the peripheral blood for at least 1 month, organ damage and/or dysfunction caused by eosinophilic infiltration, and exclusion of potential causes of secondary eosinophilia including allergic diseases and parasitic infections.
Löffler's endocarditis (LE; cardiac involvement in HES) progresses through three stages, namely acute necrotic stage, thrombotic stage, and fibrotic stage, which may overlap (2, 3). LE exhibits various cardiac findings depending on the severity and extent of the endo-/myocardial damage caused by eosinophilic infiltration (4). During the acute necrotic phase, patients present with symptoms and signs of left-sided heart failure (HF). During the thrombotic phase, patients develop cardiac thrombi and present with symptoms and signs based on embolic events such as stroke, or mass effects including secondary mitral regurgitation (MR) and ventricular cavity obliteration, respectively. During the fibrotic phase, patients develop restrictive cardiomyopathy and have symptoms and signs of right-sided HF. Uncommon cases present with symptoms and signs of coronary arteritis, aortic valve stenosis, and pericarditis (5, 6).
If left untreated, serious complications such as valvular regurgitation or restrictive cardiomyopathy may occur at an advanced stage. However, an early correct diagnosis is particularly difficult because of the subclinical presentation and the lack of characteristic signs in early disease stages.
A 77-year-old man was referred to our hospital for the evaluation of suspected cardiac abnormalities, which were detected on electrocardiogram (ECG) during a medical checkup.
The patient had a 3-year history of hypereosinophilia, for which etiologies remained unknown despite thorough diagnostic evaluation.
His vital signs were stable. He had no symptoms or signs of HF. Laboratory test results revealed elevated white blood cells (19,400/μL) with eosinophilia (absolute eosinophilic count: 9,120/μL; 47% in differential), and brain natriuretic peptide (BNP) levels (187.6 pg/mL, normal range: 0–18.4 pg/mL). Both C-reactive protein (CRP) and cardiac troponin I (cTnI) levels were within the normal range. ECG revealed ST segment depression with T-wave inversion in the precordial leads (Figure 1), which were not observed 3 years ago. Echocardiography revealed normal chamber size with normal left ventricular ejection function of 69%, despite grade II diastolic dysfunction. A large, heterogeneous cardiac mass (30 × 39 mm, arrow) with a stalk attached to the septum was noted in the apex of the left ventricle (Figure 2A, Supplementary Video 1). Color Doppler echocardiography revealed that the mass had reached the anterolateral papillary muscle (ALPM), resulting in moderate MR (Figure 2B, Supplementary Video 2). Coronary angiography was unremarkable. Contrast-enhanced computed tomography revealed a large, low attenuation intracardiac mass with several attachments to the apex of the left ventricle. Note an inhomogeneous and peripheral delayed enhancement as if the mass size had reduced (Figures 3A,B). Cardiac magnetic resonance (CMR) imaging further confirmed the cardiac mass, with myocardial tissue properties (Figures 3C,D). A short-axis image of the mid-ventricle revealed considerable late gadolinium enhancement (LGE) found subendocardially in the anteroseptal and inferior wall, and in the midportion of the lateral wall. Moreover, heterogeneous enhancement was also seen within the mass and the adjacent ALPM, strongly suggesting a cardiac tumor with surrounding invasion. Differential diagnoses included primary neoplasm (angiosarcoma or malignant lymphoma), secondary neoplasm (metastatic breast, lung or renal carcinoma), benign tumor (myxoma or hamartoma), vegetation, and thrombus.
Figure 1. Electrocardiogram reveals sinus rhythm and ST segment depression with T-wave inversion in leads V1-6.
Figure 2. (A) Transthoracic echocardiography in apical 5-chamber view reveals an echo-dense mass (30 × 39 mm, arrow) attached to the mid-anteroseptal wall of the left ventricle, extending to the anterolateral papillary muscle. (B) Color Doppler echocardiography in apical 3-chamber view reveals a cardiac mass (arrow), and entrapment of the anterolateral papillary muscle (arrowheads), causing moderate mitral regurgitation. Ao, Aorta; LA, Left atrium; LV, Left ventricle; RV, Right ventricle.
Figure 3. (A) Contrast-enhanced computed tomography scan at early phase reveals an irregular cardiac mass attached to the left ventricle in several locations (arrow). (B) Note the reduced mass with a delayed contrast enhancement at late phase (arrow). (C) Axial dynamic cardiac magnetic resonance imaging reveals a low echogenic left ventricular mass attached to the anteroseptal and inferior walls, and the anterolateral papillary muscle (arrows). (D) Late gadolinium enhancement image reveals subendocardial enhancement in anteroseptal and inferior walls, mid-wall enhancement in lateral wall, and heterogeneous enhancement within the cardiac mass and the adjacent anterolateral papillary muscle (arrowheads). LA, Left atrium; LAA, Left atrial appendage; LV, Left ventricle; pm, Papillary muscle; RV, Right ventricle.
Owing to the increased risk of exacerbation of MR or systemic embolization, the patient underwent surgical resection of the cardiac mass. In the intraoperative view, the 4 cm-sized yellowish-white mass was integrated with the left ventricular endocardium. Moreover, the boundaries between the mass and the endocardium as well as ALPM were poorly demarcated and rigid. Thus, endomyocardial resection and mitral valve replacement (MVR) with bioprosthetic valve (Magna Ease, 25 mm), combined with resection of the affected ALPM were performed in addition. Pathological examination of the resected mass revealed mixed thrombus consisting of fresh, organizing, or organized thrombus, with no malignancy (Figures 4A,B). Moreover, the resected endomyocardium and the ALPM demonstrated various changes from granulation to severe fibrosis, suggesting a fibrotic stage. Although eosinophil infiltrations were observed in the endocardium, immunostaining for major basic protein, which is one of eosinophil-specific cardiotoxic granules, showed no remarkable extracellular deposition, indicating no evidence of eosinophilic activation (Figures 4C,D). These findings led to a correct diagnosis of late-stage LE.
Figure 4. (A–D) Photomicrograph of the resected mass. (A) Low-power view with Masson trichrome stain reveals endocardial fibrosis and intracardiac thrombosis at various stages. Note the mixed thrombus consisting of well-organized thrombus (asterisk) and fresh thrombus (double asterisk). En, Endocardium; My, Myocardium; Th, Thrombus; Bars: 1 mm. (B) A high-power view reveals proliferating neovascularization (black arrows) with inflammatory infiltrates in the border zone of endocardial fibrosis and mural thrombus (magnified view around white arrow in A). Bars: 20 μm. (C) A high-power view with hematoxylin-eosin stain reveals focal eosinophilic infiltrate in the endocardium. Bars: 20 μm. (D) Immunostaining with an antibody against the major basic protein. Bars: 20 μm.
The postoperative course was uneventful. Subsequently an anticoagulant and a high dose of corticosteroid (prednisolone 20 mg daily) were initiated. The prednisolone dose was gradually tapered to 5 mg daily. No recurrence was observed during 3-year follow-up. As a supplement, we present a summarized illustration of the case presentation (Figure 5).
Figure 5. Timeline of the case. ALPM, Anterolateral papillary muscle; Ao, Aorta; Echo, Echocardiography; ECG, Electrocardiogram; En, Endocardium; LGE, Late gadolinium enhancement; LV, Left ventricle; MR, Mitral regurgitation; My, Myocardium; pm, Papillary muscle; RV, Right ventricle; Th, Thrombus. The asterisk denotes well-organized thrombus, and double asterisk denotes fresh thrombus.
Herein, we describe a case of histologically proven late-stage LE masquerading as a cardiac tumor. This case may provide several precious clinical lessons.
First, our case exhibited an atypical LE characterized by a cardiac mass, which was initially mistaken as an invasive cardiac tumor. Although LE and cardiac tumor are similar in terms of cardiac mass development, they have different prerequisite treatment strategies. Thus, the LE-associated cardiac thrombus must be clinically differentiated from a cardiac tumor.
Although laboratory tests are not specific to LE, they can sometimes be useful for detecting myocarditis or as indicators of its activity; CRP can be considered a well-known inflammation marker. Cardiac enzyme is a specific indicator of myocardial necrosis, and BNP is another marker of cardiac damage owing to HF or restrictive physiology (7). In our case, normal CRP and cTnI levels and elevated BNP levels were consistent with late-stage LE.
Echocardiography is first-line imaging modality for detection of endocardial damage of HES. During the acute inflammatory phase, echocardiography shows few significant findings. However, ventricular wall thickening corresponding to myocardial edema can be observed if the inflammatory infiltration is severe. The characteristic echocardiographic findings in LE include apical cavity obliteration of the ventricles caused by echogenic material with preserved ventricular ejection fraction (8). Its echocardiographic findings are very similar to those of apical hypertrophic cardiomyopathy or left ventricular non-compaction, leading to misdiagnosis. In addition, severe MR owing to limited posterior mitral leaflet motion, biatrial dilatation despite normal ventricular chamber size, or restrictive filling pattern can be recognized (9). In our case, echocardiography demonstrated a large heterogeneous mass with a stalk attached to the ventricular septum. Such atypical morphological characteristics identified on echocardiography might lead to misdiagnosis. Recently, three-dimensional speckle tracking echocardiography allows identifying abnormal findings of both atrial structural and functional remodeling even in asymptomatic LE patients during the acute necrotic phase, which can be valuable for an early diagnosis of LE (10, 11).
CMR is another essential non-invasive imaging tool for evaluating tissue properties and detecting thrombus in LE, and it is becoming the gold standard. Compared with transthoracic echocardiography (23% ± 12% and 96% ± 4%, respectively) and transesophageal echocardiography (40% ± 14% and 96% ± 4%, respectively), contrast-enhanced CMR has excellent sensitivity and specificity for detecting left ventricular mural thrombi (88% ± 9% and 99% ± 2%, respectively) (12). CMR allows the visualization of myocardial inflammation and fibrosis and the differentiation of inflammation from fibrosis based on the enhancement on LGE imaging (2). Typical CMR findings for LE include the following: CMR using the steady-state free precession technique shows diffuse subendocardial thickening of the ventricle. T2-weighted imaging shows diffuse subendocardial hyperintensity signal in the ventricle, suggesting the presence of inflammatory edema. The LGE imaging study demonstrates a characteristic three-layer appearance in the biventricular apex composed of the myocardium (outermost layer), diffuse subendocardial delayed enhancement indicating either wall edema or fibrosis or both (middle layer), and overlying hypointense area, consistent with mural thrombus (innermost layer) (13, 14). Moreover, several recent novel quantitative CMR imaging techniques, such as feature tracking-based strain analysis and T2-mapping, allow myocardial deformation analysis and myocardial edema assessment, respectively (15). Thus, multiparametric CMR is very useful for comprehensive tissue characterization, including assessment of myocardial perfusion, edema, and fibrosis, and can allow non-histological diagnosis, staging, and treatment monitoring of LE (16).
However, in our case, cardiac thrombus showed patchy distribution, not a null signal on LGE imaging, which is considered to be its more conventional finding; to the best of our knowledge, this is the first such report of a case with LE. The absence of LGE in a cardiac mass is believed to be one of the key findings in distinguishing thrombus from a tumor, since it implies avascular structures (17). However, a thrombus can have various signal intensities on CMR imaging since thrombus composition depends on its origin and age. While fresh thrombus includes a different fibrin-platelet rich composition, chronic thrombus can include neovascularization, calcification, and fibrotic or connective tissue deposition. There is some strong evidence to suggest that organized thrombosis may display heterogeneous enhancement on LGE imaging (18), supporting this notion. Also, peripheral delayed enhancement in contrast-enhanced computed tomography might have reflected a similar phenomenon.
However, the LV mass was notable despite the absence of LV wall motion abnormalities in our case; based on the presence of hypereosinophilia, the findings suggested endocardial damage owing to eosinophilic infiltration. These mismatched findings might be crucial for correctly diagnosing a rare disease. Endomyocardial biopsy remains the gold standard to diagnose LE and might provide more information for the preoperative diagnosis of LE in our case.
Second, combined surgical interventions and sequential medical treatments were feasible with favorable outcomes in our case. The treatment of LE consists of three strategies: suppression of tissue eosinophilic infiltration, counteracting inflammation, and prevention of fibrosis and thrombus formation. In addition, specific treatment is required according to the underlying cause of HES and the disease stage in each case. Based on previous case reports and a small number of case series (2), therapeutic interventions are initiated in a stepwise manner, usually starting with supportive care for HF, followed by medical treatment, and finally surgical intervention. However, the treatment outcome depends on the disease stage. Conventionally, a combination of immunosuppressive treatments including corticosteroids and anticoagulants is very effective in the control of early-stage LE (19). Similarly, surgical intervention can be avoided in many cases of LE with valvular involvement (often with mitral valve, sometimes aortic valve) (5, 20).
If the clinical picture is progressive or the disease is unresponsive to medical treatment, the disease is highly likely to be in an irreversible stage (21). However, no clear guidelines exist for treatment of late-stage LE, which is similar to the endomyocardial fibrosis (EMF). Ultimately, it is believed that orthotopic heart transplantation can be the only curative treatment for EMF. Although inconclusive owing to limited experience, endocardial decortication with/without atrioventricular valve repair or replacement is an acceptable option, which can improve symptoms and long-term survival in patients with EMF (22).
In the current case, endomyocardial resection with MVR, and subsequent combination of anticoagulation and corticosteroids were also effective. In fact, our patient could not receive proper treatment as described above. Retrospectively, considering that our case was in the histologically proven irreversible stage complicated by secondary MR, which indicated drug resistance, the surgical intervention might have made sense. However, there are great concerns about the increased risk of obstructive valve thrombosis, the long-term durability of biological valves, and the recurrence of fibrosis (23). The efficacy of anticoagulants and corticosteroids remains controversial. Further investigation is needed.
Finally, ECG monitoring was a helpful screening test for detecting LE.
Although most patients present with symptoms and signs of HF, our patient exhibited an asymptomatic cardiac mass with ECG abnormalities. A review of 65 cases demonstrated T-wave inversion on the ECG in 35% of cases, which was strongly associated with cardiac dysfunction (24). ECG monitoring is also effective for suspecting LE in our case.
The leading cause of morbidity and mortality in patients with HES is cardiac dysfunction. However, the development of cardiac involvement is unpredictable because there is not always a positive association between circulating eosinophil levels and eosinophil-mediated cardiac damage. Moreover, unawareness of this rare clinical entity, and non-specific symptoms is frequently related to missed or delayed diagnosis, leading to disease progression. Given the limited treatment approach in an irreversible stage, making an earlier diagnosis is crucial for appropriate treatment of LE.
Thus, we propose a diagnostic algorithm for suspected LE using a comprehensive approach comprising clinical and biochemical data, multimodality imaging, and careful monitoring (Figures 6, 7). LE should be highly suspected if persistent hypereosinophilia in combination with one or more red flags is observed. Subsequent multiparametric CMR allows non-histological diagnosis, disease staging, and evaluation of treatment response reliably. If necessary, clinicians should not hesitate to perform an endomyocardial biopsy to obtain additional information. Continuous careful monitoring is essential even if a single test is negative for LE.
Figure 6. Red flags that should be highly suspected of Löffler's endocarditis. ECG, Electrocardiogram; Echo, Echocardiography; 3DSTE, Three-dimensional speckle tracking echocardiography; LA, Left atrium; RA, Right atrium; GLS, Global longitudinal strain; LV, Left ventricle; RV, Right ventricle; MV, mitral valve; AV, aortic valve.
Figure 7. Diagnostic algorithm for patients with suspected Löffler's endocarditis. LE, Löffler's endocarditis; –, negative test; +, positive test; CMR, Cardiovascular magnetic resonance; SSFP, Steady-state free precession; T2WI, T2-weighted imaging; LGE, Late gadolinium enhancement; FTA, Feature-tracking based strain analysis; IHC, Immunohistochemistry; EM, Electron microscopy; ECG, Electrocardiogram; Echo, Echocardiography.
We described a case of histologically proven late-stage LE presenting as a cardiac mass, which was successfully treated with the combination of surgical intervention and sequential medical treatment. Clinicians should be aware of pitfalls in multimodality imaging of thrombus, and should consider the possibility of this rare clinicopathological entity in the differential diagnosis of cardiac mass. A comprehensive approach comprising clinical and biochemical data, multimodality imaging, and careful monitoring can be helpful for detecting LE.
Data Availability Statement
The original contributions generated for this study are included in the article/Supplementary Material, further inquiries can be directed to the corresponding author/s.
Consent for Publication
The authors confirm that written consent for submission and publication of this case report, including the images and associated movie, has been obtained from the patient.
TK was responsible for the clinical design and conceptualization. TK, MM, TI, and ST were involved in the acquisition of the clinical data. TK, HY, MM, and JI analyzed and interpreted the data. TK and HY wrote the manuscript. All authors discussed, read, and approved the submission of this manuscript to the journal.
Conflict of Interest
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
The Supplementary Material for this article can be found online at: https://www.frontiersin.org/articles/10.3389/fcvm.2020.589212/full#supplementary-material
Supplementary Video 1. Transthoracic echocardiography in the apical 5-chamber view shows a markedly enlarged cardiac mass originating from the mid-anteroseptal wall of the left ventricle, extending to the anterolateral papillary muscle.
Supplementary Video 2. Color Doppler echocardiography in apical 3-chamber view shows a heterogenous cardiac mass with entrapment of the anterolateral papillary muscle, causing moderate mitral regurgitation.
HES, Hypereosinophilic syndrome; LE, Löffler's endocarditis; HF, heart failure; MR, Mitral regurgitation; ECG, Electrocardiogram; ALPM, Anterolateral papillary muscle; CMR, Cardiac magnetic resonance; LGE, Late gadolinium enhancement; MVR, Mitral valve replacement; EMF, Endomyocardial fibrosis; BNP, Brain natriuretic peptide; CRP, C-reactive protein; cTnI, Cardiac troponin I.
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Keywords: hypereosinophilic syndrome, Löffler's endocarditis, cardiac thrombus, cardiac magnetic resonance, endomyocardial fibrosis
Citation: Koyama T, Yamamoto H, Matsumoto M, Isogai J, Isomura T and Tanaka S (2020) Late-Stage Löffler's Endocarditis Mimicking Cardiac Tumor: A Case Report. Front. Cardiovasc. Med. 7:589212. doi: 10.3389/fcvm.2020.589212
Received: 30 July 2020; Accepted: 05 October 2020;
Published: 29 October 2020.
Edited by:Steffen Erhard Petersen, Queen Mary University of London, United Kingdom
Reviewed by:Aloha Meave, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico
Maria Concetta Pastore, University of Piemonte Orientale, Italy
Copyright © 2020 Koyama, Yamamoto, Matsumoto, Isogai, Isomura and Tanaka. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Hiroyuki Yamamoto, firstname.lastname@example.org


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Colour talks, I’d like for it to work with me, not against me. Picking the right palette is like going back to school; spending hours going over different schemes and learning the theory behind them. I have good and bad hue days. There are times where I’ve chosen a wrong palette and have only noticed half through colouring in. I abruptly ( ok, not that dramatically) stop, put my mouse to the one side and start over.
I’m a beige soul, gold at heart and tread safely with neutral shades. I first pick a focal shade and work my way around it, by throwing every single colour in the book at it, until I find the right match.


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A BRITISH tourist has claimed she was raped by another Brit holidaymaker in Magaluf, leading to his arrest.
The woman- who has not been named- told Spanish cops she passed out at the man's hotel room and woke up later to find him “on top of her”.
The two Brits, both in their 20s, allegedly met while partying in Punta Ballena on Friday.
According to the local paper Ultima Hora the woman blacked out in the tourist's hotel room.
She told police she woke up hours later to find the man “on top of her”.
Based on the woman's description of the suspect, detectives who went to the hotel arrested the man on Saturday.
READ MORE IN SPAIN
Brit tourist, 53, drowns in swimming pool at four-star hotel in Majorca
Brit tourist, 19, ‘faces being paralysed’ after smashing head in pool dive
He was held in police custody before appearing in court on Monday where a judge agreed to release him pending an ongoing inquiry.
Prosecutors did not demand his remand in prison after he admitted to the judge he had sex with his female accuser but insisted it was consensual.
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Cigarettes, cards and laughter
Serene Assir finds downtown Cairo to be a breath of fresh air for women in an increasingly conservative capital
"Funny how the centre manages to resist the norms set by all that surrounds it," says one regular downtown-goer as we walk through Talaat Harb Street, on our way to one of Cairo's more popular baladi cafés.
Indeed, as we enter a backstreet, home to a café frequented by artists and idlers, businessmen and misfits, we witness living proof of this. A cigarette-touting 20-year-old who wears the hijab, Yasmin, is looking down at her cards. Concentrating, she throws down the winning set, celebrating her victory over three men.
Meanwhile her husband Ahmed, who also frequents downtown cafés, is chatting away with his friends; he shows no sign whatsoever of being disturbed or shocked by his wife's behaviour. "Of course it's fine by me that Yasmin enjoys herself," he told Al-Ahram Weekly. "It's only in this area that people understand normal behaviour. Anywhere else, people will be shocked, assuming the worst."
"For me," Yasmin explained, once her card game was over, "downtown Cairo is an addiction. I live in Giza, but I keep returning to the cafés here. All my friends are here, and only here can my interaction with them be truly free. Anywhere else, as a woman, I feel misunderstood -- my movements have to be guarded, I must watch my voice and how hard I laugh."
While female freedom of expression outside the confines of the home or, as it were, the limits of "trusted" territory is gradually becoming a rarity, many feel that central Cairo is different. "It's not just about cigarettes, cards or laughter," Yasmin went on. "For me, it's the way people here understand a woman's right to be as she is at home, or as she is with her close friends and family, that this does not contradict her being a good, decent human being."
Follow traditional descriptions of the city, the huge area encompassed by central Cairo includes all that lies between the Hussein and Tahrir Square. Within these neighbourhoods is what has come to form the most integral components of the capital's history -- from Fatimid mosques to Mamluk architecture, from relics of the British protectorate to post-Revolution buildings.
Central Cairo will also continue to house -- if probably not for long -- all that constitutes the power of the state, ranging from ministries to that huge beacon of Egyptian bureaucracy, the mugamma. Accompanying such features are all the state regulars, including plain-clothes policemen and, it is rumoured, informers paid to listen in on political conversations in backstreet cafés.
It is interesting, yet not surprising, that only under pressure of history and the state do men and women alike choose to be at their freest. For this area is older, and fuller in character, proud to be the truest urban heart of the country -- something no other part of the city can boast.
"This café may be run-down," Yasmin says as she takes another drag on her cigarette. "But try going to a café in Mohandessin or Zamalek, and you'll instantly notice the way people interact with you -- it will be just smeared by their warped perception of how a woman should or should not behave in public."
The secret to this may be that, in a way, downtown Cairo belongs to nobody. "You'll notice that nobody who comes to these cafés is actually from here," Yasmine's friend Shirine elaborates. "It is precisely this mix of people that makes the centre so attractive. We choose to hang out here not because it's near our homes, or because of its familiarity. We come because everyone is accepted, and though we may sometimes have problems, on the whole people are very accepting of others."
Similarly, Yasmine says, "I'm surprised to have met so many people from so many walks of life, all in one place. I may not agree with what some of them say about politics and religion, but at least open debate is allowed among us."
Indeed, central Cairo seems to accommodate the homeless more effectively than mainstream Egyptian society. "You should see Maysoun," Yasmine says. "She's a little girl -- she can't be any older than 15. It's such a shame she lives the way she does, on the streets, and God knows how she manages to earn her next meal. Downtown Cairo is also her home, for better or for worse."
Shirine regrets having to put up with the down-and-outs of the capital within the space she occupies. "I find it disturbing that prostitutes hang out in the same places as I do," she says. "They make it possible for the men of the area to judge me in a bad light too, although I don't consider any of what I do or say wrong. I simply come here to be with my friends."
But in spite of this fear, Shirine will keep coming back. "Even if sometimes I get very frustrated and annoyed with this area, simply because of what it represents to me and the problems it can bring to the surface," she attests, "I can only return. It's funny that I should say this, but I feel that central Cairo is my home. It's in my nature to be here."
"It may not be pleasant sometimes," Yasmine chimes along, "but in the end I feel that only in the centre do people shed their conservatism and embrace the city for what it really is, for better or for worse, and with all its variety."