text:
Central Retinal Vein Occlusion (CRVO) is the second most common retinal vascular disease (the first being diabetic retinopathy), and is associated with cystoid macular oedema (CMO) that causes vision loss [1, 2]. Intravitreal injections of anti-vascular endothelial growth factor (VEGF) agents are the mainstay of treatment for CMO due to CRVO, but although each of the available agents (ranibizumab, bevacizumab and aflibercept) has demonstrated high efficacy and excellent safety profiles for the treatment of this common condition, very few comparative trials have been published regarding these agents.
The SCORE2 study, published in 2017 , compared bevacizumab and aflibercept for the treatment of CMO due to CRVO. It included 362 patients who were randomized 1:1 and received 6 monthly injections of either agent. At 6 months, the mean improvement in visual acuity (VA) was 18.6 letters in the bevacizumab group and 18.9 letters in the aflibercept group, demonstrating that bevacizumab is non-inferior to aflibercept for the treatment of this condition.
Last month, the results of the LEAVO study were published . This trial compared all three anti-VEGF agents (bevacizumab, ranibizumab and aflibercept) for the treatment of CMO due to CRVO, and included 463 patients who were randomized 1:1:1. Patients in all groups received four mandatory monthly injections, and thereafter retreatment was based on specific pre-defined criteria, and were followed for 2 years. At 2 years, the mean improvement in VA was 12.5 letters for ranibizumab, 15.1 letters for aflibercept, and 9.8 letters for bevacizumab. Fewer injections were administered over the 2 years in the aflibercept group than in the ranibizumab and bevacizumab groups (mean of 10 vs 11.8 and 11.5, respectively). It should also be noted that the rates of more than three lines of VA improvement were similar in all groups (47%, 52% and 45% for ranibizumab, aflibercept and bevacizumab, respectively), and that no differences in safety were noted between groups. Specific comparisons using intention-to-treat adjusted mean BCVA difference showed that aflibercept demonstrated non-inferiority compared to ranibizumab, but that bevacizumab was not non-inferior to either ranibizumab or aflibercept.
Although these results did not demonstrate that bevacizumab is significantly worse for the treatment of CMO due to CRVO, they were inconclusive regarding the VA changes at 2 years, and raised the possibility that the choice of the initial anti-VEGF agent may determine the long-term outcomes of treatment.
Thus, we have somewhat different outcomes from two well-designed clinical trials, SCORE2 and LEAVO. This can be explained by significant differences between these two trials. First, the SCORE2 study was only 6 months long, while LEAVO was 2 years. The difference between drugs may manifest itself only after a longer time interval. Second, patients received monthly injections in SCORE2, while in LEAVO after the first four injections monitoring was every 4–8 weeks and re-injections were determined by specific criteria, and patients received injections in longer intervals in this study. Thus, in SCORE2 patients received more intensive therapy during the first 6 months. The difference between drugs maybe smaller is the drugs are used in a very intensive manner. Third, the SCORE2 study included patients with hemi-retinal vein occlusion (HRVO), which has a better prognosis, while LEAVO did not. Fourth, LEAVO included patients with better initial VA (upper limit of 78 letters compared to 73 in SCORE2), which may have caused a ceiling effect in the VA improvement.
In many countries, mostly due to economic reasons, bevacizumab is commonly used as the initial anti-VEGF agent for the treatment of CMO due to CRVO, and real-world results from recent tears have indicated good outcome [5, 6]. It is possible that with different monitoring and injection frequencies, the results would have been closer for all three anti-VEGF agents in the LEAVO trial. Still, it seems that for the regimen used in the LEAVO trial which is the most common regimen used, although good outcome was achieved with all three anti-VEGF drugs available today, the use of bevacizumab was not non-inferior to ranibizumab and aflibercept, a fact that needs to be considered when it is given as first line to our patients.
The Eye Disease Case–Control Study Group. Risk factors for central retinal vein occlusion. Arch Ophthalmol. 1996;114:545–54.
The Central Vein Occlusion Study Group Natural history and clinical management of central retinal vein occlusion. Arch Ophthalmol. 1997;115:486–91.
Scott IU, VanVeldhuisen PC, Ip MS, Blodi BA, Oden NL, Awh CC, et al. SCORE2 Investigator Group. Effect of bevacizumab vs aflibercept on visual acuity among patients with macular edema due to central retinal vein occlusion: the SCORE2 randomized clinical trial. JAMA. 2017;317:2072–87.
Hykin P, Prevost AT, Vasconcelos JC, Murphy C, Kelly J, Ramu J, et al. LEAVO Study Group. Clinical effectiveness of intravitreal therapy with ranibizumab vs aflibercept vs bevacizumab for macular edema secondary to central retinal vein occlusion: a randomized clinical trial. JAMA Ophthalmol. 2019. [Epub ahead of print].
Jumper JM, Dugel PU, Chen S, Blinder KJ, Walt JG. Anti-VEGF treatment of macular edema associated with retinal vein occlusion: patterns of use and effectiveness in clinical practice (ECHO study report 2). Clin Ophthalmol. 2018;3:621–9.
Wecker T, Ehlken C, Bühler A, Lange C, Agostini H, Böhringer D, et al. Five-year visual acuity outcomes and injection patterns in patients with pro-re-nata treatments for AMD, DME, RVO and myopic CNV. Br J Ophthalmol. 2017;101:353–9.
Conflict of interest
None of the authors have any proprietary interest in this publication.
Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
About this article
Cite this article
Moisseiev, E., Loewenstein, A. Initial treatment of macular oedema due to central retinal vein occlusion—which anti-VEGF agent to choose?. Eye 34, 219–220 (2020). https://doi.org/10.1038/s41433-019-0706-6

domain: literature


text:
LOGAN - The annual tax revenue numbers for the Logan County Board of Education were recently released, and they are down nearly $3 million from last year.
In fiscal year 2018-19, total tax revenues for Logan County Schools was $18,157,780.22, which was nearly $3 million less than the 2017-18 total of $21,016,783.88. The new number was, however, closer to the 2016-17 total of $18,757,970.55, which LCBOE Vice President Dr. Pat Joe White said was a result of a coal company paying owed back taxes.
During the regular session of the LCBOE on Tuesday, July 23, White raised concern with the new number because it is the lowest tax collection total of the past five years.
"I know we've had a lot of requests to do a lot of things, and we do have a lot of repairs that need to be done, but we're really going to have to look hard before we reach an agreement on what we're going to do, because these tax collections I don't really think that they will increase," White said. "I may be wrong, and I hope I am, but it was a very alarming bit of information when I looked over that information this evening."
Board member Barry Mullins responded with a gloomy outlook, saying that the demand for steam/thermal coal, which is mainly used for electricity production and is the primary kind of coal produced in the region, is declining while the demand for metallurgical coal, used in production of steel, is up.
LCBOE President Debbie Mendez said that each school in the county is going to have to begin assessing what they absolutely need, rather than what they want. She added that, in the future, the board members will begin taking trips to each of the schools to assess what they need.
Board member Jeremy Farley blamed the decrease in tax collections on lower property valuations in the county along with a decrease in student enrollment. He said the decrease in enrollment is due to a wide variety of factors, from families moving away to an increase in homeschooling and private school.
"This is not just a Logan County trend, this is a West Virginia trend," Farley said. "But as we've seen, we've had to be very careful about our budget situation, but those are two things that, as a board and as an administration, we've kept an eye on, because I want to be hopeful, but I don't have a lot of hope that next year we will have a higher student enrollment than we did this year or that we will collect taxes at a higher rate than what we did this year, so we have to look at that total picture and then try to make the decisions on how we're going to move forward as a board."
According to Assistant Superintendent Darlene Dingess-Adkins, Logan County Schools lost more than 200 enrolled students last year compared to the year before it.
Dylan Vidovich is a news reporter for HD Media. Contact him by phone at 304-896-5196.

domain: finance


text:
|Women strip naked to protest incessant killings in Southern Kaduna (photos) by Nairaplace(m): Fri Jul 2020 08:08am|
Hundreds of women from Southern Kaduna state, today July 23, took to the streets naked to protest the incessant killings recorded in the area.
Some of the protesting women wore black cloths in the protest that terminated at the palace of Atak Njei, Agwamatyap Palace (Sarkin Atyap palace) of Zangon Kataf local government area of Kaduna State.
The aggrieved women wept profusely, stating that the continued killings has taken away their breadwinners, parents, sisters, brothers, husbands and children, adding that today majority of them are widows.
They called on relevant stakeholders, government, security agencies and the international community to come to their aides and save them from further killings and destruction of their properties.
In the last four days, the area has witnessed two attacks with over 20 persons killed by the assailants.
|RE: Women strip naked to protest incessant killings in Southern Kaduna (photos) by Nairaplace(m): Fri Jul 2020 08:58am|
Viewing this topic: , and 1 guest(s)
Nairaplace Forum - Copyright © 2015 - 2020 Nairaplace Forum. All rights reserved.
Disclaimer: Every Nairaplace Forum member is solely responsible for anything that he/she posts or uploads on Nairaplace Forum.

domain: sociology


The third and fourth Cross Country models to join Volvo’s portfolio are now available to order as Volvo Car UK announces pricing and specification levels of both the S60 Cross Country and the V60 Cross Country.
A busy week as manufacturers reflect on the end of 2014 and their sales success, we bring you the first weekend update of the 2015, for the week 5th-9th January
Volvo Cars is stepping up to meet the demands of its core customers with the unveiling of the exciting S60 Cross Country at the Detroit Auto Show.
Volvo Car Group (Volvo Cars) this week officially started series production of the Volvo S60L at its manufacturing plant in Chengdu, China.
The new Volvo S60, V60 and XC60 – shown to the public for the first time at the Geneva Motor Show – can be fitted with an innovation that makes driving in the dark safer and more comfortable.
Extensive CO2 and fuel efficiency gains with no price changes on new automatic Volvos are set to deliver significant savings to company car drivers and their employers.
Volvo Car UK has announced the launch of the all-new S60 and V60 R-Design models – created to deliver a dynamic driving experience in a coupé-style saloon or versatile Sportswagon. Featuring a specially developed chassis, the new R-Design models ensure that the driving experience matches the car’s sporting appearance.


text:
Memphis, TN (SportsNetwork.com) - Isaiah Sykes poured in 36 points and grabbed nine rebounds as the UCF Knights outlasted the Temple Owls 94-90 in double overtime during the first round of the American Athletic Conference Tournament at FedExForum.
Tristan Spurlock contributed 19 points, eight rebounds and five blocks for ninth-seed UCF (13-17), which advances to face top-seed Cincinnati. Calvin Newell chipped in 13 points and Kasey Wilson contributed 12 points and 10 rebounds.
Quenton DeCosey scored a career-high 28 points and Will Cummings tallied 25 points and nine assists for Temple (9-22). Dalton Pepper tacked on 14 points and seven assists and Anthony Lee netted 17 points.
Temple held a slim 40-39 lead at halftime after shooting an even 50 percent from the field, including 5-of-10 from 3-point range, in the first half. UCF stayed close, sinking 45.7 percent from the field, including 7-of-15 from beyond the arc.
A 3-pointer from DeCosey gave Temple a 75-70 lead with 2:31 left in regulation. Sykes answered with a 3-pointer and a jumper in the next 30 seconds to even the score. The game was still tied in the final seconds, after the teams traded free-throws, when Sykes nearly ended things. However, his apparent buzzer-beater was called off after a video review.
UCF had a lead (82-78) late in the first extra session, but Pepper hit a pair of free-throws and Cummings scored on a layup off a steal to tie things at 82-82. Sykes missed a 3-pointer as time expired to send the game to another overtime.
A 7-2 run to start the second extra session gave the Knights a bit of a cushion, but the Owls slashed their deficit to one on a 3-pointer from DeCosey with six seconds left. Newell then hit two free-throws on the other end to put UCF up 93-90. Pepper was sent to the line for the Owls on the ensuing possession, and he missed both free-throw attempts, the second of which was intentional. Unfortunately UCF came down with the ball and Spurlock split a pair of free-throws to ice the win.

domain: game


text:
Studies Prove That Meditation Keeps You Young
Scientists now have proof that people who meditate just 10 minutes a day can slow the aging process of their bodies considerably.
According to the Journal of Behavioral Medicine, scientists recently compared the levels of an age-related hormone called DHEA-S (dehydroe-paindosterone sulfate) in meditators to those of people who don’t meditate.
ln’the study, the level of DHEA-S of 423 meditators was compared to that of 1,252 healthy non-meditators. The subjects were divided into groups according to their age. Meditators were compared to nonmeditators who were in the same age group.
Meditating females showed higher levels of DHEA-S levels than nonmeditatiing women in every age group. Men under age 40 showed little variation, but after age 40, meditators began to show significantly higher levels of the youth hormone than nonmeditators.
Scientists have also long noted that over a lifetime, people who have meditated for 10 years or more have lifespans that are 20 years longer on average than people who do not meditate.
What Kind of Meditation is Best?
No doubt, the word meditation has conjured up some scary or negative images in many of you . Perhaps you pictured Zen monks with heads shaved doing weird things in a monastery on some remote mountaintop, or long-haired, freaky hippy people smoking pot and sitting in a cross-legged position.
But not all meditation is so far out. In fact, meditation can be as simple as finding a quiet, undisturbed place to sit while you calm down, count your breaths and clear your mind of your worries for 10 minutes each day.
Meditation is not necessarily associated with any particular religion, although many religions employ it as part of their practices. You can choose to meditate simply as a way to calm down and get control of your life.
It doesn’t take a lot of time. You are not required to buy any expensive equipment. You don’t need a teacher and you don’t have to enroll in a class to learn how to do it better.
Here is an easy kind of meditation you can try, and which just about anyone can perform successfully:
(1) Find a quiet room where you will not be disturbed by people, telephones or distracting noise from televisions or radios.
(2) You can either sit in a chair or lie flat on your back with your arms at your side. If you sit in a chair, you should not slouch, but sit straight up so that your spinal cord is perpendicular with the floor and ceiling. A firm table chair is best. A soft chair or a soft bed to lie on may put you to sleep. You do not want to go to sleep.
(3) Once you have yourself positioned, you should take three deep breaths to relax. Tell yourself that you will relax a bit more after each deep breath.
(4) After the three breaths, you should start counting your breaths. Count one inhale and one exhale as one, the next inhale and exhale as two, and so on. When you get to four, start over with one and proceed again to four, and so on.
(5) You should keep as much of your attention as possible on your breathing. The object of meditation is to clear the mind, but the problem is, the more you try the harder it will be. A key is not to try too hard, or perhaps riot to try at all, if that makes sense. Instead of trying to fight off your thoughts, just let them flow through your mind. Let them come and go without paying much attention to them. Just keep reminding yourself that the breathing is your primary concern right now. When your thoughts stray away and get caught up within themselves, gently but firmly bring your thoughts back to your breath counting.
(6) You may find this simple meditation deceptively difficult. Even if it’s just for 10 minutes, keeping your mind clear is remarkably difficult to do. Lots of thoughts are always crowding in and clamoring to be heard. But don’t be daunted if you feel like you are not succeeding at first. . It’s the process itself that is what we are after, not the result. When it comes to meditation, the road itself is the goal, and not what lies at the end of the road.
That’s it. If you set aside 10 minutes each day, or perhaps twice a day, and practice this simple breathing meditation exercise, you can add 20 years to your life.
It almost seems too simple, doesn’t it? Well. Albert Einstein once said that it takes a genius to see the obvious. When it comes to meditation, you don’t have to be a genius to do something that’s incredibly simple, yet most enormously beneficial to your overall life.
Return to the words of wisdom, the ruminations index..
Church of the Science of God
La Jolla, California 92038-3131
© Church of the Science of GOD, 1993

domain: psychology


text:
DALLAS (CBSDFW.COM) – A shooting in south Dallas sent two people to the hospital early Friday morning, and left a third person injured. The incident happened just after 2:00 a.m. in the 2100 block of Stovall Drive.
According to police, a 28-year-old woman exited a house and was confronted by a man. He wanted to take the woman to his home, but she declined. A brief argument took place with the man showing a handgun. The woman screamed and ran inside. Two men — ages 28 and 32 — then came out of the home to help the threatened woman. The suspect fired his handgun at the two men and inside of the home.
The 28-year-old man was struck multiple times and transported to Methodist Dallas Medical Center with serious injuries. The 32-year-old man was taken to Baylor Medical Center at Dallas with less severe injuries. Meanwhile, the woman in this incident was struck by glass that was shattered by a bullet. She received minor injuries, but was not admitted to the hospital.
There was also another 28-year-old woman and two children — ages 6 and 7 — inside of the home when shots were fired. None of them were injured during the incident.
Police are still conducting an investigation. The suspect has not been found.
Also Check Out:

domain: news


text:
If you or someone in your family has chronic obstructive pulmonary disease (COPD), or if you think you may be at risk, explore this page to find answers to your questions and resources that are available to help you.
Although COPD cannot be cured, it can be effectively treated. Doctors can help people with COPD feel better, live active lives, and slow the damage to their lungs. The earlier COPD is detected, the better the results of treatment.
Could It BE COPD?
Chronic obstructive pulmonary disease (COPD) is a major cause of illness, yet many people have it and don't know it.
If you answer these questions, it will help you find out if you could have COPD.
This short questionnaire was developed by GOLD and has been scientifically evaluated and shown to identify people who are more likely to have COPD.
"Could it be COPD?" Questionnaire
- Do you cough several times most days?
- Do you bring up phlegm or mucus most days?
- Do you get out of breath more easily than others your age?
- Are you older than 40 years?
- Are you a current smoker or an ex-smoker?
If you answered yes to three or more of these questions, ask your doctor if you might have COPD.
Finding COPD early gives the best chance to prevent further lung damage. However, treatments are available to help people at all stages of disease feel better and live a more active life.
An information guide for patients and their families. (NOTE: This document is in the public domain and is not under copyright.)GOLD Patient Guide: What You Can Do About a Lung Disease Called COPD
Ce Puteti Face Daca Suferiti De o Boala de Plamani Numita BPOC?
Translation provided by Mihaltan Florin, MD, Institute of Pneumology, Bucharest, Romania
GOLD (Global Initiative for Chronic Obstructive Lung Disease) is protected by worldwide copyright and trademark laws and regulations and the name, logo and material related thereto may not be copied, reproduced or excerpted in any manner without GOLD's prior approval. Except where otherwise noted, all GOLD documents are protected by copyright.

domain: health


text:
A Killer Night
Like many other nights of revelry, this night of revelry was enjoyed by a group of sophisticates, artists and hoodlums …. until things went horribly wrong.
It was the night of Friday 16th April, at The Star Club (Deb and Paul’s new home), a large group of swanky flappers, bootleggers, and gangsters enjoyed a night of mystery and intrigue. The dimly light Star Club was filled with the sounds of Jazz, and an abundance of 1920’s memorabilia, set up by our wonderful hosts.
As the canapes and cocktails flowed, conversations grew louder, but the discovery of the body of Felix (Steve C) left the guests in shock and nervous that the cops would turn up. A private investigation took place, and everyone was a suspect. A scavenger hunt for seven clues pursued, and the guests were given a chance to examine and review them. The ensuing interrogation gave guests an opportunity to discuss their knowledge, ask questions of one another, level accusations and make their defences. It was quickly apparent that there were only four viable suspects. Duke (Gary B), Edgar (Guy), Judith (Ann D) and Edith (Deb Br).
In the end, everyone had the opportunity to cast a vote for who they thought the killer was. This raucous group voted on Edgar as the killer, and they were correct.
What a troupe of misfits our wonderful Mannas are.
Thank you, Deb and Paul, and everyone for an awesome night of fun and friendship.

domain: artistic


text:
Who we are
Greystones Family Doctors
Greystones Family Doctors opened its doors in 2017 as a newly established, purpose-built GP Surgery. We are located in the Blacklion Centre beside the Lidl. There is free parking as well as wheelchair & buggy access to our Surgery.
Services that Greystones Family Doctors provide
Read Our Latest Articles
What our patients think
Niamh McGovern2020-08-12Great surgery. The building is modern and clean. The doctors are excellent. Recommend.Clare Salley2020-05-20What a great doctors. Always there to help and have been brilliant with the kids. Highly recommend themMaria Lisovski2018-12-15Same day appointment, excellent service!Myles O'Shaughnessy2017-10-02Excellent care, very family friendly environment. Convenient location with plenty of parking and easy access.Caroline Boland2017-09-20Totally professional, yet friendly and reassuring at the same time. Looking forward to watching this new practice grow and prosper.

domain: medical


text:
Hotel and casino resort just a short distance from the Las Vegas strip
Located just a mile from the world-famous Las Vegas Strip, the Gold Coast Hotel Las Vegas offers guests an ideal environment in which to work, rest, and play.
The Gold Coast Hotel and Casino features 711 guestrooms, 86,000 square feet of gaming space, a host of event rooms, numerous eateries, and an assortment of recreational choices. Guests will find plenty to keep them occupied before they even board a shuttle bus to the Strip.
Each of the guestrooms includes a 32 LCD TV with cable channels and In-Room movies, a direct dial telephone, coffee maker, clock radio, iron and ironing board, and hairdryer. All rooms feature air-conditioning and internet access (for an additional charge), as well as a private en-suite bathroom. Guests can request a rollaway bed or crib, as well as refrigerator to rent.
A number of exclusive suites are also available for those that fancy a little extra indulgence and luxury.
Guests are welcome to make use of the hotels fitness center which is equipped with a range of cardiovascular machinery and weights, or the outdoor resort style swimming pool. As well as being ideal for a few laps, guests can also relax beneath the Nevada sunshine, thanks to a number of sun-loungers. Those wishing to look their best will find a beauty salon and barber shop on the premises.
Business visitors to the Gold Coast Hotel Las Vegas Gold Coast Hotel Las Vegas will find an assortment of conference and function rooms. These are able to accommodate 700 diners or 800 business delegates. As such, the Gold Coast Hotel and Casino makes for a suitable venue no matter what the event or occasion.
The hotels casino offers 48 gaming tables and more than 2,100 slot machines, bringing the glitz and excitement associated with Las Vegas right to guests feet. Punters visiting the casino can enjoy traditional casino games, such as Blackjack and Poker, or place a bet against the race and sports book.
Its not all about gambling though. The hotel also offers a number of other activities for guests to enjoy, including ten-pin bowling, lounge entertainment, and a number of headline performers.
The Cold Coast also offers a variety of eateries for guests to select from. The nine dining options range from sit-down restaurant to a sports bar and an ice cream parlor.
Of course it wouldnt be a trip to Las Vegas without visiting those famous landmark sites. The hotel and casino offers a shuttle service to the Las Vegas Strip where visitors can admire the likes of the Bellagio Hotel and Casino, Caesars Palace, and the MGM Grand, all famous establishments along Las Vegas Boulevard. At night time the millions of light bulbs that illuminate the district make for a truly stunning sight. Visitors can pass by the likes of the Sphinx, the Eiffel Tower, and the Statue of Liberty without ever leaving the neon glare of the strip.
After a hard days or nights entertainment, guests can return to the Gold Coast Hotel Las Vegas and enjoy a comfortable and relaxing rest.

domain: entertainment


text:
Animation news and discussion. toonzone provides cartoon, comic book, movie and video game news, information and community to enthusiasts.
In Episode #4 of Toon News, Chad discusses concept art and cast members from the upcoming Disney animated feature, Frozen, Cartoon Network’s 20th anniversary and Monsters U. For more LewToons, be sure to check out Chad’s LewToons Youtube Channel, Twitter and blog.
09.02 - 10:00 AM - Bubble Guppies
09.03 - 10:00 AM - Bubble Guppies
09.03 - 08:00 PM - Disney Channel Movie
09.03 - 09:00 PM - Wild Grinders
09.03 - 09:30 PM - Rush Zone: Guardians Unleashed
09.03 - 10:00 PM - Wild Grinders
09.03 - 10:15 PM - Wild Grinders
09.04 - 12:00 PM - Dora and Friends: Into the City!
09.05 - 07:30 AM - Chuggington
09.05 - 08:00 PM - Disney Channel Movie

domain: hobby


text:
Litercurious Book Review
|Title||Dangerous Shallows: In Search of The |
Ghost Ships of Cape Cod
|Author||Eric Takakjian & Randall Peffer|
|Publisher||Lyons Press (January 24, 2020)|
|ISBN # 10 / 13||1493042300 / 978-1493042302|
WHO IS THE TARGET AUDIENCE
This book is for everyone. It doesn’t matter whether you’re a sailor, a diver, a history buff, an adventurer, or you just like a good thriller; this book has it all.
Dangerous Shallows: In Search of The Ghost Ships of Cape Cod is a superbly written book that grips the reader from the very onset. Eric Takakjian takes the reader from the earliest of times in relation to diving techniques to modern mixed gasses. He intersperses his experiences with spellbinding tales of sunken ships and the events that led up to their tragic fates.
Eric explains in terms that are easy to understand all of the intricacies of diving and especially deep diving. He guides us through the uses of mixed gas to get to exceptionally deep wrecks and the troubles associated with each dive. He brings into view the price of miscalculation and bad circumstance and the lethal effects associated with deep diving. Intermixed is his own journey as a USCG crewman through his marriage and operating his own dive company while looking for those “virgin” wrecks.
Dangerous Shallows covers a myriad of different vessels and reasons for their current predicaments. The wrecks that Eric explores cover centuries of accidents, war, and depression. He takes the time to relate to the reader exactly what he sees and feels as he dives the wrecks. While swimming over the wrecks, he takes the reader back in time and makes the reader feel as if they are there for each vessel’s demise. The reader can feel the panic, the elation, the fear, or the determination of the people associated with each vessel.
Included within the book are the stories of his own trials and tribulations. He talks about the hardships keeping “virgin” wreck locations secret and the betrayal of “friends” who want to use his work for their own gains. He explains the research he, his wife, and friends undertake to locate and find each lost vessel. Eric describes the dangers each particular dive has; from currents, to sharks, to visibility issues, to the “bends.”
The author interfuses pictures and illustrations throughout the book. The color and black and white photos enhance the readers perceptions of the boats and the wrecks. Some of the photos are historic as are the schematics.
This book is thrilling, mysterious, and intriguing. Even if you don’t know much about diving and especially deep diving, this book easily explains the terms and conditions. The stories of the individual wrecks are told in vivid detail. The reader can easily feel as if they are right there with him on this journey of discovery. I heartily recommend this book for everyone.
I would like to thank Eric Takakjian and Randall Peffer, NetGalley, and Lyons Press for affording me the opportunity to review Dangerous Shallows: In Search of the Ghost Ships of Cape Cod.


text:
(Photo by Hussein Shaharuddin/The Mole)
Tun Razak Exchange of previously known as KLIF (Kuala Lumpur International Financial district) is a 26 billion development that was launched on 2012 as as effort to put Kuala Lumpur into the international financial map. The total development tenure of the project is set at 15 years with several phases. At the time of writing, development of this project has started.
Prime minister Datuk Seri Najib Tun Razak Launched KLIF project which was later renamed to TRX. Land ground clearing process for TRX development has started. The first physical construction is expected to start on 2013.
Aabar Investments PJSC and Abu Dhabi investment arm will be investing significantly on Malaysia’s Tun Razak Exchange development. WCT won the multi evaluation stage tender for ground clearing and ground works which is valued at RM 169 million. Earth works, basement and civil works has started. China’s Exim bank became a partner investor for TRX project.
Construction works is expected to commence on early 2015.
Phase One (2017)
The first phase of TRX project is set to be completed on 2017 that is in line with Malaysia’s plan to achieve high capital income nation and developed nation status on 2020. Development of first phase will includes two five star hotels, five residential towers, four office blocks and one retail mall
Around RM 3.5 billion foreign direct investment is projected with investment from 100 different companies and 500,000 employment opportunities to be created with phase one launch. The first phase completion will also coincides with opening of TRX MRT station on 2017.
Projected final completion of TRX project.
Source – tunrazakexchange.com
Food for thought: With the massive transformation in Malaysia, particularly Kuala Lumpur (KL) now, it is indeed a great timing and opportunity for investors to enter the market for business set up, bringing foreign talents and of course real estate investment. Being a frequent visitor and a real estate investor to KL myself, I have observed the tremendous transformation taking place and still ongoing for many years to come.
It is like watching Singapore growing 10 years back. You can imagine the opportunities ahead and what property prices would be in the future. I think you I know your answer. Awesome!


text:
There is something uniquely annoying about having an otherwise peaceful journey disrupted by another person’s telephone conversation and now scientists have found why. A study shows that overheard calls are more distracting than other background talking.
The study, published in the journal PLOS One, studied how overhearing either one side of a mobile phone call or a chat between two people affected people’s attention and memory.
Participants in the study were asked to complete a task involving anagrams. In the background, the scientists read out a short, scripted conversation.
Half the participants overheard one side of the conversation carried out on the phone, and the rest overheard the discussion as a conversation between two people in the room with them.
Those who overheard the one-sided…


text:
The hexadecimal color code #0019db is a shade of blue. In the RGB color model #0019db is comprised of 0% red, 9.8% green and 85.88% blue. In the HSL color space #0019db has a hue of 233° (degrees), 100% saturation and 43% lightness. This color has an approximate wavelength of 465.06 nm.
Buy paint matching this color
I wish they would only take me as I am.

…

The object isn't to make art, it's to be in that wonderful state which makes art inevitable.

…

Art is the stored honey of the human soul.

…


text:
This panel was used as an architectural element and has the mortise cuts in the top which were used to hold the panel in place. It is one of a pair of panels which were taken from the temple...
Measures 3 inches tall, and comes with original hand twisted cord, and is in very good condition
24 x 9 x 7 inches...hand carved from one solid piece of wood.
The "Sarinda" musical instrument was used for centuries in various countries in Central Asia, primarily in Rajasthan (Northern India), Pakistan, Nepal, Afghanistan, and Baluchistan...
the bag is roughly 10 x 12 inches and has a generous amount of cording for adjustable straps.
Possibly carved from cryptomera wood and darkened with age, this carved figure has both a simplicity and elegance which are, for me, the major characteristics of Japanese asthetics.
there are no rips and no tears but clearly these shoes were worn numerous times.
Price on Request
The vest dates to the mid 19th century and has a front rank badge with bird facing the wearers left shoulder. This indicates that the original owner was the wife of a civil official. The bird on this rank badge is a made of matching embroidery and fabric sepa...


text:
William Kirby's Le Chien d'or / The Golden Dog, a dramatic historical romance that vividly details the intertwined French and English foundations of Canada, is one of the nation's best-known pieces of nineteenth-century literature. A complicated publishing history, however, resulted in severe distortions of the text, so that each edition of the novel moved further from the author's original vision. Now, in the final work produced by the Centre for Editing Early Canadian Texts at Carleton University, editor Mary Jane Edwards returns this beloved piece of literary history to its intended form. First published in 1877, Le Chien d'or draws upon the threads of legend spun around the real-life tablet of the Golden Dog, which can still be seen in Quebec City. The novel's author William Kirby begins his tale in the 1740s, with the murder of the prosperous merchant who lived in the house that bore the tablet, and brings his work to a tragic end that coincides with the destruction of France's North American empire. Weaving historical, literary, and religious allusions together with a powerful lyricism, Le Chien d'or develops an epic narrative of the heroic past and promising future of the Dominion of Canada. Though many versions of Le Chien d'or have been published in both French and English, very few people have read what the author intended to see in print. This edition brings Kirby's unfulfilled legacy full circle by presenting a critically reliable version of his iconic Canadian novel.
Subjects: Language & Literature
Table of Contents
You are viewing the table of contents
You do not have access to this
on JSTOR. Try logging in through your institution for access.


text:
Scheme 1: Left: The Mitsunobu reaction is essentially a nucleophilic substitution of alcohols occurring with inversion of configuration at the alcohol stereocenter.
The auxiliary reagents are involved in a redox process. Scheme 1: Left: The Mitsunobu reaction is essentially a nucleophilic substitution of alcohols occurring with Jump to Scheme 1 The reaction proceeds under mild, neutral conditions that are compatible with a wide range of functional groups. In the case where a stereogenic center is involved, the reaction takes place with stereochemical inversion . Otherwise the azo reagent would compete with the acidic nucleophile and participate in the substitution reaction .
Various compounds comply with that condition: carboxylic acids, phenols, hydrazoic acid, some other NH acids, and thiols. However, alternative reagents such as azodicarboxamides [15,16] or stabilized phosphoranes were also developed to allow reaction with nucleophiles of weaker acidity.
The typical phosphine reagents are triphenyl- Ph3P or tributylphosphine n-Bu3P. In recent years, advances have been made using solid supported reagents, thus facilitating work-up conditions [17,18]. The polarity of the commonly aprotic solvents used in the Mitsunobu reaction, including toluene, tetrahydrofuran or dimethylformamide, has been shown to be influential in terms of efficacy and stereoselectivity . Since its infancy, the Mitsunobu reaction has found applications in carbohydrate chemistry, as its broad scope and mild conditions are ideal for the formation of conjugates with sensitive natural products.
Standard applications of the Mitsunobu reaction in glycochemistry have mostly dealt with the functionalization of the primary hydroxy group of sugars and, to a lesser extent, with modifications of the secondary alcohol array in carbohydrate rings  , for example for halogenation .
However, the Mitsunobu reaction can also be profitably utilized for the anomeric modification of carbohydrates. Hence, we have focused this review on the utilization of the Mitsunobu reaction for manipulations of the carbohydrate hemiacetal, where reducing anomerically unprotected sugars react as the alcohol component to be either converted into glycosides or into other anomerically modified carbohydrate derivatives. We intend to provide a critical survey as well as a source of inspiration, even more so as glycosylation remains a challenge in carbohydrate chemistry.
To rationalize the outcome of the Mitsunobu reaction with reducing sugars, special mechanistic considerations have to be taken into account. On the one hand, the equilibrium between the azodicarboxylate, the phosphine, and the acidic component, Nu-OH, is important cf. On the other hand, mutarotation of the sugar hemiacetal has to be discussed to predict the stereochemical outcome of the reaction.
However, full anomerization is often not observed as the rate and the extent of mutarotation depends on various parameters such as anchimeric effects of neighboring groups and the reaction conditions. Another possible explanation for limited anomerization lies in the different stability of anomeric glycosyloxyphosphonium salts, where one anomer can be sterically favored over the other, thereby pushing the equilibrium to a product with the respective anomeric configuration.
Especially when the sugar alcohol is not sterically hindered, phosphorus transfer occurs to yield a phosphine-activated anomeric alcohol a glycosyloxyphosphonium ion, pathway A. This in turn can be attacked by the deprotonated nucleophile resulting in an anomerically modified carbohydrate with inversion of configuration at the anomeric center, according to a SN2 mechanism.
Pathway A can also proceed through a SN1 mechanism when the intermediate glycosyloxyphosphonium ion is less stable. Then, it can decompose into the corresponding anomeric oxocarbenium ion and phosphine oxide. While this would lead to racemization under normal circumstances, in most carbohydrates, participation effects of neighboring groups in the vicinity typically at the 2-position of the sugar ring affect the reaction outcome, favoring nucleophilic attack from a preferred face of the sugar ring [22,23].
In the absence of a substituent at C-2, however, typically poor stereoselectivity is observed in Mitsunobu reactions with carbohydrate hemiacetals, indicating a SN1-type pathway A of the reaction .
Scheme 2: Mechanistic considerations on the Mitsunobu reaction with carbohydrate hemiacetals depicted in simplified form. These can give rise to at least two different reaction pathways, A and B, as explained in the main text. Depending on various parameters, the anomerically modified sugar, a glycoside or an anomeric ester, respectively, is obtained with full inversion of anomeric configuration or as anomeric mixture A , or with retention of the anomeric configuration via O-alkylation B.
For clarity both reaction pathways are exemplified with only one sugar anomer. Scheme 2: Mechanistic considerations on the Mitsunobu reaction with carbohydrate hemiacetals depicted in sim This in turn reacts with the anomeric oxyanion to furnish the anomerically modified sugar with retention of configuration via anomeric O-alkylation.
This mechanistic proposal is in agreement with observations by Lubineau et al. Reactions with protic acids to achieve anomeric esters The first application of the Mitsunobu reaction involved esterification of a secondary alcohol.
Although an anomeric OH group cannot be regarded as a classical secondary alcohol group but as a hemiacetal OH, it can be successfully involved in Mitsunobu reactions to achieve 1-O-acyl glycoses. Thus, searching for an efficient protocol for the preparation of complex, multifunctional glycosyl esters in the context of the total synthesis of phyllanthostatin antitumor agents, A.
Smith and colleagues soundly investigated the suitability of the Mitsunobu reaction . In addition, 4 was also converted with the phyllanthostatin aglycone 8 to give 10 with inversion of anomeric configuration. Extension of this work to other more complex antineoplastic glycosyl esters was successfully investigated by the same group . Scheme 3: Anomeric esterification using the Mitsunobu procedure . Jump to Scheme 3 De Mesmaeker et al. Similarly, regioselective esterification of unprotected allyl glucuronide 11 was performed by Juteau et al.
Scheme 4: Conversion of allyl glucuronate into various 1-O-esterified allyl glucuronates using anomeric Mitsunobu esterification [36,37]. Scheme 4: Conversion of allyl glucuronate into various 1-O-esterified allyl glucuronates using anomeric Mitsu Jump to Scheme 4 Bourhim et al. On the other hand, other authors have reported that the anomeric position can be selectively modified in a Mitsunobu reaction without concomitant modification of the primary 6-OH vide infra.
Apparently, fine-tuning of reaction conditions can alter the selectivity of the Mitsunobu reaction and in addition, different regioselectivities might origin in the structure of the sugar substrate. The produced esters 27—29 were obtained as anomeric mixtures.
Scheme 5: Synthesis of anomeric glycosyl esters as substrates for Au-catalyzed glycosylation . Jump to Scheme 5 Lubineau et al. The authors state that the observed pKa effect is either due to the influence of the acidity of the employed acid on the reaction mechanism or results from the proton-catalyzed change of the anomeric ratio of the starting material 30 in solution. Scheme 6: Correlation between pKa value of the employed acids or alcohol and the favoured anomeric configuration of the respective product.
Scheme 6: Correlation between pKa value of the employed acids or alcohol and the favoured anomeric configur The authors thus considered the Mitsunobu reaction as unsatisfactory for the synthesis of HBP. On the other hand, Inuki et al. Jump to Scheme 7 Reactions with phenols to achieve aryl glycosides Not only anomeric esters, but also glycosides can be obtained through the Mitsunobu reaction.
Dehydrative glycosylation approaches with reducing sugars were previously reviewed [43,44]. As phenols are weak acids, they are suitable reaction partners in the Mitsunobu reaction, leading to aryl glycosides with reducing sugars as the alcohol components.
Grynkiewicz can be called the pioneer of Mitsunobu glycosylation, as having explored the Mitsunobu reaction for the synthesis of various aryl glycosides [24,45]. Scheme 8: Synthesis of phenyl glycosides 44 and 45 from unprotected sugars . Notably, in this reaction, traces of an anomeric mixture of the respective furanoside 48 were detected. Singh, and Xi Chen. Chemical Reviews , 5 , Christine F. Czauderna, Amanda G.
Jarvis, Frank J. Heutz, David B. Cordes, Alexandra M. Organometallics , 34 9 , Le Goff, and Audrey Auffrant. Organometallics , 33 21 , Serrano, Juliette Fitremann, and Luis Oriol. Chemistry of Materials , 24 20 , Inorganic Chemistry , 51 4 , Serrano, and Luis Oriol. Langmuir , 27 24 , Suman Reddy, A. Ansari, and Yashwant D. The Journal of Organic Chemistry , 76 15 , Jaemoon Yang,, Gregory J. Mercer, and, Hien M. Organic Letters , 9 21 , Organic Letters , 9 22 , Recent progress using the Staudinger ligation for radiolabeling applications.
Journal of Labelled Compounds and Radiopharmaceuticals , 61 3 , International Journal of Chemical Kinetics , 50 1 , Conversion of glycals into vicinal-1,2-diazides and 1,2- or 2,1 -azidoacetates using hypervalent iodine reagents and Me 3 SiN 3. Application in the synthesis of N-glycopeptides, pseudo-trisaccharides and an iminosugar. RSC Advances , 7 66 , Sara Tejera, Rosa L. Study of aryl triazoles for absolute configuration determination. Tetrahedron: Asymmetry , 27 , Luz M. Rosado, Terence J.
Meyerhoefer, Saqib M. Bett, Saba. Ilyas, Lubabalo. Bululu, Carla A. Martin, Troy W. Joseph, Michael De Castro. European Journal of Organic Chemistry , 16 , Identification of gallic acid based glycoconjugates as a novel tubulin polymerization inhibitors.
Bis azide—triphenylphosphine as a reagent for esterification at room temperature. Tetrahedron Letters , 56 50 , Debabrata Bhunia, Preethi M.The authors thus considered the Mitsunobu reaction as unsatisfactory reducing sugars, special mechanistic considerations have to be taken. To rationalize the outcome of the Mitsunobu reaction with glycosyl esters was successfully investigated by the same group. Extension of this work to synthesis more complex antineoplastic to study and build upon so that you're ready. Such Master thesis in public finance was also extended for the synthesis of.
Serrano, and Luis Oriol. Conversion of glycals into vicinal-1,2-diazides and 1,2- or 2,1 -azidoacetates using hypervalent iodine reagents and Me 3 SiN 3. Scheme Synthesis of disaccharides using mercury II bromide as co-activator in the Mitsunobu reaction . Pathway A can also proceed through a SN1 mechanism when the intermediate glycosyloxyphosphonium ion is less stable.
Bis azide—triphenylphosphine as a reagent for esterification at room temperature. Another possible explanation for limited anomerization lies in the different stability of anomeric glycosyloxyphosphonium salts, where one anomer can be sterically favored over the other, thereby pushing the equilibrium to a product with the respective anomeric configuration. Scheme Synthesis of various fructofuranosides according to Mitsunobu and proposed neighbouring group parti Scheme 4: Conversion of allyl glucuronate into various 1-O-esterified allyl glucuronates using anomeric Mitsunobu esterification [36,37].

domain: chemistry


An insulated glass unit (IGU) is made up of two or more glass panes that are hermetically sealed. There is air or gas between the glass panes and the panes are joined by a spacer, usually made of aluminium. The panes are affixed to the aluminium spacer by butyl and a sealing compound (resin based mastic). Butyl mass makes the IGU airtight, preventing humid outside air from entering the unit. The butyl seal is applied on the aluminium spacer and between the panes. Thus the butyl seal prevents thermal bridging, otherwise the aluminium spacer would conduct cold to the inner pane and produce condensate on the glass surface. The air or gas between the panes is dried with a special desiccant inside the spacer which absorbs moisture.
Several different types of glass may be used in an IGU, depending on the purpose of the window: patterned glass, laminated glass, tempered glass, glass of different structure, etc. Plasto can offer a wide array of insulated glass units.
ALLOWED GLASS DIMENSIONS:


And if you begin to see that those who are not working?
Thursday, 03 of December 2015
- Per BNY Mellon Investment Management
And if you begin to see that those who are not working? What would happen? This is one of the questions that are being asked more and more managers and investors. And those who come to make conclusions difficult to take. Aron Pataki, manager Newton, a subsidiary of BNY Mellon, is shown strong in his belief that the policy of quantitative easing (QE) serve more to boost growth of "virtual" wealth for sustainable economic recovery. "The verification of this could lead to a review of the value of risk assets and downgrading" he says. The main problem encountered by the team Newton Real Return is that "we have been living the illusion of a perpetual money machine where spending financed by debt continues to grow. The ultra low interest rates have encouraged market participants to accumulate more debt, which probably makes the generated unsustainable economic growth.
"The "debt" is one of the topics of investment through which Newton discusses the major changes affecting the world economy, as noted Pataki. He explains that the cheap money has reduced the volatility of prices and encouraged investors to reduce liquidity portfolios. It has also pushed investors towards riskier assets, hoping that by taking on more risk, it may be possible to achieve even greater profitability, says the manager. In this regard, remember that stock markets posted strong gains despite reduced earnings and ongoing disappointment with regard to global economic growth.
"Bad economic news can not remain permanently good news for investors in asset growth, even if it brings more stimulus policies," he says. "We believe that investors end up losing confidence in the ruling finding that the policy of quantitative easing, mostly, driving the growth of wealth that can be defined as virtual and do not lead to a sustainable economic recovery. This could cause a major overhaul the value of risky assets and downgrading. The failure of the Fed when it comes to normalize monetary policy after seven years of zero rates would be the obvious trigger that would make investors efficiency QE question and therefore, the credibility of central banks.
"For Pataki, the empirical evidence suggests that, in practice, the unorthodox monetary policy has a non-inflationary deflationary effect, as reflected in the continued decline in the velocity of circulation of Money and pricing power of firms in other words. the opposite of what is intended, "said Pataki. "It is also important to note that these policies are not without costs; negative unintended consequences often outweigh the short-term benefits."
"It's hard to know what the ultimate consequences of low interest rates will be, but you're likely to see its impact is amplified by an increase in leverage and dangerous mismatch between risk assets and the holders of these assets risk, "said Pataki. "This will cause volatility in unexpected places. If economic activity continues to fall, defaults probably go back up. And in a distorted by central bank policy environment, in which investment banks hold less risk, liquidity could be the key factor over bank solvency (as was the case in 2008), "says the expert.


text:
Gurudwara Charan Kanwal
Gurdwara Charan Kanwal at Machhiwara marks the site of the garden where Guru Gobind Singh had a sip of water and a spell of brief sleep. It was here that his three devotees Bhai Mani Singh, Bhai Daya Singh and Bhai Dharam Singh joined him. The sacred shrine commemorating the historical event, has a beautiful building, worthy of the holy tradition. An annual congregation fair is held in December, corresponding to 9th & 10th of Poh, the days of Guruji stay at Machiwara.
Another shrine popularly called Gurdwara Chubara Sahib is located at Machhiwara. Here at the house of Masand Gulaba where the Guru spent the night. The place is known as 'Gulaba da Chubara'.
It is here that the Guru sang the shabad "Mitra Pyare Nu". The Gurdwara is supplied water from the same well believed to be the one from which garden was watered during those days. An annual congregation fair is held in December, corresponding to 9th & 10th of Poh, the days of Guruji stay at Machiwara.
Gurdwara Charan Kamal Sahib is situated on Charan Kamal Road in the city of Machiwara, near Bus Stand. It is connected by road to Ludhiana-Chandigarh highway at Samrala (42 km) and to Ropar (46 km) by Guru Gobind Singh Marg.
- The Manager,
- Gurdwara Charan Kamal Sahib,
- P.O. & Tehsil Machiwara,
- Distt. Ludhiana, Punjab
- Phone : 01628-250190

domain: travel


I don't know if you've noticed, but it's already October, also known as the best time of the year, as fall is kicking in to full gear and it seems like everybody wants to sit down to watch a scary movie all month long, leading up to Halloween. Yes, it's good to be a horror fan in October.
Along with the excuse to watch a different horror movie every day this month, there are other things like contests looking to hone in on the time of year. Specifically, AMC is hosting a YOUR GREATEST FEAR contest--all you have to do is send in a one minute video of your greatest fear (in the form of a narrative, a scene, mini-documentary, dream sequence, etc.), and you could win the grand prize of $4,000 cash and have your video aired during one of AMC's upcoming Fear Friday specials! How cool is that?
If you don't win the to prize, maybe you'll get into the top 10--hey, there's a prize for that too! Horror movie DVDs don't have quite the ring of cold hard cash... then again, who doesn't love getting free horror DVDs? Quantity of DVDs nor exact titles are known, but I'm sure the selection will be awesome.
Did I mention Rob Zombie is judging the entries to help determine the winner? Because he is. Yes, the Rob Zombie. To check out all the details on the contest and how to enter, click HERE. You better hurry, the contest only lasts until Halloween, so start crackin'! Winners will be announced November 30th. And if you end up winning, drop us a line and let us know (I'll be expecting a cut of the prize money as a 'finder's fee). Good luck!


text:
Melt the butter and stir through the onions, cover with a lid and cook for 10 minutes or until softened. Remove lid, add sugar, then cook for 15-20 minutes or until golden and sticky.
Fry the sausages for 15 minutes or until browned and keep warm. Add the onions, then flour and stir for 1 minute. Add thyme, beer and stock and simmer for 5 minutes. Add Worcestershire sauce, season and serve with sausages.
Make the coleslaw by mixing all the ingredients together. Serve with the sausages.

domain: food


text:
WACO, Texas (KXAN) – Newly released surveillance video from inside the Twin Peaks Restaurant shows leather-clad customers drawing weapons and diving for cover.
Around 170 people were arrested following the May 17 shootout that left 9 people dead and 18 injured.
The Sunday afternoon shooting broke out on a day where a group of biker members gathered for a planned meeting in the restaurant’s outdoor bar area. Those jailed, killed or injured were not from the Waco area.
After initially locking up more than 170 people in connection with the May 17 incident outside Twin Peaks restaurant, McLennan County prosecutors have not charged anyone with the shooting deaths of nine people. At least 20 others were hurt.
Those arrested were charged with engaging in organized criminal activity.
The shootout in the parking lot of the restaurant erupted during an apparent confrontation between rival biker gangs.
Investigators have not yet offered details about who shot who or whether police officers fatally shot anyone, though reports reviewed by The Associated Press indicate police bullets did hit at least one biker.
Among the dead in Waco was Jesus Delgado Rodriguez, 65, of New Braunfels . .
“He was a very, very close friend of a lot of us,” said Myles Gonzales, vice president of the Cycle Stylez Motorcycle Club, who said he was a friend of Rodriguez. “It was a very, very sad moment to hear that he had passed away. And I will never let it be in vain.”
Gonzales spoke with KXAN News in May at Austin City Hall. There, he and group of motorcycle club members posed with Mayor Steve Adler to highlight motorcycle safety.
As of Thursday afternoon, no one arrested in connection with the shooting in Waco had been indicted, according to the McLennan County District Clerk’s office.


text:
Regina publisher Deana Driver from DriverWorks Ink is excited to introduce Tunnels of Time by Mary Harelkin Bishop to a whole new generation of readers with a revival of Moose Jaw’s most beloved novel.
In a partnership between DriverWorks Ink and Bishop herself, a reprinted and updated edition of the young adult novel set in Moose Jaw’s infamous tunnels is hot off the presses this week and ready to release with SaskBooks during Saskatchewan Book Publishing Week from Sept. 28 to Oct. 2.
“We’re looking forward to introducing this book to a whole new generation of young people and educators who have not heard of it before,” said Driver. “It’s a national best-selling book, tens of thousands of copies sold, and we’re hoping people embrace this new volume just as well.”
Tunnels of Time was originally published in 2000 by the now-defunct Coteau Books in Regina, and it instantly became a bestseller for the prairie publisher. The time-travel novel was so popular that Bishop turned it into a series of five books following pre-teen heroine Andrea and her adventures in Moose Jaw’s illustrious past, which have remained very popular over the years since they were originally published.
The new edition of the novel will tell the same beloved story as the original version, but with a few new inclusions to both celebrate the book’s 20th anniversary and also bring Tunnels of Time into 2020.
Driver and Bishop have updated parts of the novel to better reflect new information about the history of the tunnels and the prohibition era in Moose Jaw, in light of new research done since 2000 — including a documentary interviewing Al Capone’s great-niece talking about how important Moose Jaw was to his business.
“Some of the details have been fine-tuned because in 20 years things have changed,” said Driver. “More information is known about the tunnels and the days of gangsters, and all of that history.”
Driver and Bishop even reached out to people in Moose Jaw to put together a more accurate depiction of the city for the novel, using details from local stories to better describe Moose Jaw’s locale.
They have also updated some of the outdated language from the original edition and added a number of resources at the back of the book, including historical notes and a question and answer section with the author for educators to utilize.
The 2020 edition of Tunnels of Time also boasts a new cover and illustrations throughout the novel, something that Bishop had always wanted to do.
“Now people get to see who Mary thinks Andrea is, this 13-year-old girl who’s the heroine of the story,” said Driver. “They now know what she looks like and they can follow along a little better on her journey and all of the different adventures she has as a tunnel rat.”
Tunnels of Time has been a staple in prairie classrooms for a number of years, and Driver said the book’s longevity is thanks to its incredible story.
“Part of the reason we republished is because this book is still relevant. It's a wonderful children’s story based on events that actually happened in Moose Jaw, in the days of Al Capone,” said Driver. “The book is super popular across Canada and we knew that we could not allow it to go out of print.”
DriverWorks Ink will be celebrating the book’s 20th anniversary and republishing on Oct. 2 with a virtual book launch, which will feature a live Q&A with Bishop and a dramatic reading of an excerpt from the novel — filmed in the actual tunnels of Moose Jaw.
“[SaskBooks] thought it would be a wonderful idea to film a videotaped reading from in the tunnels of Moose Jaw,” said Driver. “And we were welcomed with open arms to come into the tunnels [and] it really was a wonderful adventure.”
The launch event is free to attend, with registration available by visiting DriverWorks Ink’s website.
Republishing Tunnels of Time is only the beginning as well, promised Driver, as DriverWorks Ink plans to update and republish all of the books in the Tunnels of Time series over the next few years.
Signed copies of the new edition of Tunnels of Time will be available to purchase from DriverWorks Ink. Regular copies can be found in big bookstores like Indigo and McNally Robinson, and they will also be available locally in Moose Jaw at Yvette Moore Gallery and the Tunnels of Moose Jaw gift shop. The new edition is also available as an eBook, for download where eBooks are available.


Software architectures are commonly utilized to maintain overall project control. The underlying conceptual arrangement of a software system is defined as software architecture. It defines the structure and behavior of system components, as well as their interactions with other systems and user interfaces.
It entails making high-level software design decisions, such as selecting software patterns, components, and frameworks, as well as assigning functional and non-functional requirements. Software architecture serves as a blueprint for the creation, implementation, and management of a software system, assisting in the achievement of desired quality features such as scalability, dependability, security, and maintainability.
A software design pattern that prioritizes the generation, detection, and consumption of events as the primary means of communication and coordination among software components or services inside a system is known as event-driven architecture (EDA). Data flow and control in an event-driven architecture are determined by the occurrence of events rather than by a central program or process.
Occurrences in this architecture reflect significant system occurrences or changes such as user activities, sensor readings, database updates, or messages from external systems. When an event occurs, it calls an event handler or event listener, who is in charge of processing the event and implementing the relevant actions or replies.
Event-driven architecture offers several benefits, including loose coupling between components, scalability, extensibility, and the ability to handle asynchronous communication and distributed systems. It is commonly used in systems that require real-time responsiveness, complex event processing, event-based integration, or handling of large volumes of data and events.
There are several benefits of an event-driven architecture, including:
Event-driven architectures and programming paradigms have become increasingly popular in modern software development due to their ability to handle complex and dynamic systems. By capturing and processing events, applications can quickly respond to changes and provide a more responsive user experience.


Merry Christmas and Happy Holidays from the Bolton Volunteer Fire Association. We are hosting our annual Christmas tree pickup fundraiser again this year. We will be picking trees up on December 30th 2023 and January 6th 2024.
Donations through fundraisers like the Christmas tree pickup help with events such as Touch-a-Truck and the Santa Parade. This past year was a big year for Bolton Volunteer Fire Association, as we hosted the 96th Annual Wachusett Muster. This event brought firefighters and families from the North Central Massachusetts area to watch firefighters compete in events that test their skills and speed. It was a great day of camaraderie for the firefighters and fun for all of the spectators. This event was funded 100% by the Bolton Volunteer Fire Association.


text:
If you grew weary of the recent harsh winter, you are not alone. But the snow crews at three Commonwealth airports in Boston, Bedford, and Mansfield are being recognized for keeping air travel disruptions to the absolute minimum.
The Balchen/Post Awards are named for pioneering aviators Wiley Post and Col. Bernt Balchen and given each year to airports whose “snow crews” did exemplary work in maintaining their airports in safe and operational conditions during the winter season. The 2010-2011 awards included:
Boston Logan International Airport– Winner, Large Commercial category
Logan and Hanscom are operated by the Massachusetts Port Authority. This is Logan's 3rd award in the past six years, this year sharing the award with LaGuardia Airport. Chicago O'Hare received honorable mention. Last winter, Logan’s snow crews battled more than 80 inches of snow with recent innovations including flush taxiway edge lights which allow crews to plow to the edge of the pavement without the buildup of large windows, and laptop computers in Airport Operations vehicles to provide real-time field condition reporting and access storm tracking radar data on the airfield.
Methuen Rotary: New I-93 Northbound Ramp Opens July 30 posted on Jul 25
MassDOT’s Methuen Rotary Interchange Reconstruction Project reaches a major milestone on Saturday, July 30, when the first new ramp of the reconstructed interchange opens to traffic. The new I-93 northbound on-ramp is located approximately 400 feet east of the current ramp. A new signal will …Continue Reading Methuen Rotary: New I-93 Northbound Ramp Opens July 30
Longfellow Bridge: Next Stage of Construction to Begin in August posted on Jul 22
MassDOT’s contractor is scheduled to begin the next stage of construction on the Longfellow Bridge in August 2016 now that the MBTA Red Line trains have been moved to their new locations. In this stage, bridge rehabilitation work will occur under the MBTA outbound track. …Continue Reading Longfellow Bridge: Next Stage of Construction to Begin in August
Maynard: Assabet River Rail Trail to Connect with MBTA Station posted on Jul 21
MassDOT Highway Administrator Tom Tinlin today joined local legislators to break ground on the Assabet River Rail Trail construction project in Maynard. The $6.7 million project links the Assabet River National Wildlife Refuge with the downtown Maynard business district as well as the MBTA South …Continue Reading Maynard: Assabet River Rail Trail to Connect with MBTA Station

domain: geography


If you have an event and would like something different, why not get in touch with us, Tribal Fantasy.
We support many events, especially for charity. Our troupe is always looking for opportunities to dance, have fun and help raise money for good causes.
Adding Sparkle to any event.
With sequins, rich colours and sensuous dancing, Tribal Fantasy brings something different to your event.
Our aim is to show that this is a form of dance that suits all ages, shapes and sizes. We love to dance, and our enthusiasm is infectious, you may even want to join in!!
For further details please use our Contact Us page.


Take me back: The power of nostalgia in advertising
Ads that use nostalgia are powerful and more likely to go viral, so why is it rarely used? Find out how nostalgia in advertising can help connect with people on a deeper, more emotional level.
The emotions that come with nostalgia can be as extreme as they are diverse. Looking back to the rose-tinted past can bring tears of joy or tears of sadness, and sometimes a combination of the two. Nostalgia is a powerfully emotive creative tool and was one of the key trends we saw across many of this year’s Kantar Creative Effectiveness Awards winners.
Nostalgia is a sense of sentimentality for the past, which can be triggered by places, objects or anything with personal memories and associations from a previous time. One classic example in the UK is the original Hovis ad, taking us back to the ‘good’ old days. Our imaginations encourage us to believe that the past existed in a purer form; like escapism, it is a journey of the mind. This deep level of transportation, also known as a ‘Proustian moment’ – an involuntary sensory-induced, vivid and emotional reliving of events from the past – can be triggered by any sense, without any thought processing. Escapism also a theme we saw in this year’s winning Creative Effectiveness Awards ads, differs from nostalgia in that it is more of a ‘conscious’ mental diversion used to avoid boring or unpleasant aspects of daily life, either via our imagination or through entertainment.


text:
Wings Over Big South Fork Air Show Set
By 2nd Lt Kimberly Bennett
Public Affairs Officer
Tennessee Wing CAP
Civil Air Patrol Volunteers from across Tennessee are headed to Scott County for the Wings Over Big South Fork Air Show at the Scott County Airport. The all day event, Saturday, Sept. 13, will be the destination for airplanes from all over the southeast.
CAP volunteers, numbering more than 80 cadets and senior members, will begin to arrive at the airport late Friday evening and Saturday morning. With adult volunteers supervising, cadets ages12-21 will have two main responsibilities during the Air Show: on the flight line assisting pilots in parking their airplanes upon arrival, and directing them as they prepare to take off and providing crowd safety by maintaining a protective barrier between the air show attendees and ground movements of dozens of aircraft.
With the air show in its fifth year, attendance has grown to an expected crowd of more than 20,000. The event features four acrobatic acts, parachute jumping, and WWII War Birds. There will also be food, music, and a fireworks display Saturday evening.
With more than 1,000 members in Tennessee, Civil Air Patrol squadrons from across the state will be in attendance for this event.
Cadets and Senior Members are traveling from Nashville, Chattanooga, Knoxville, Oak Ridge, Greeneville, Morristown, Sevierville, Murfreesboro, and Dayton.


text:
Noted producer AVM Saravanan has written his experiences about production of films in his ' 60 years old’ production company, after he took over under the title “AVM 60-CINEMA”.The 496 page book was released at a simple function in AVM studios complex. Director SP. Muthuraman released the book and superstar Rajinikanth received the first copy.
Saravanan has come out with many hitherto untold details and anecdotes with each of the films that AVM produced after he became a part of the production team. It isa well-written and researched book with photographs of Directors, Actors, Actresses, Lyrists, Music directors and technicians who were part of AVM production company.
Each copy of the book carries with it a DVD on the AVM institution as a free gift. This DVD is Edited and Directed by Director SP. Muthuraman.

domain: library


Publication: Achieving adaptation in medium-sized cities: the contribution of urban climate transition strategies in increasing soil permeability
Soil sealing and land take have produced negative impacts on urban areas, leading to adverse phenomena such as loss of ecosystem services, the urban heat island effect, and flooding. In this critical context, increasing soil permeability through desealing interventions is considered an effective solution against these problems. Over the past years, desealing has begun to be recognised in the scientific literature and in spatial planning practice to meet various needs. The approaches to desealing considered today are either top down, as a result of political actions and choices by local and regional governments, or bottom up, i.e. promoted by local associations. Within this complex framework, the aim of this contribution is to investigate and compare some specific innovative strategic urban planning instruments in medium sized cities, specifically the Sustainable Energy and Climate Action Plans (SECAPs), which were examined focusing on how these tools have interpreted and proposed desealing interventions. Keywords: desealing, soil sealing, climate change, adaptation, urban planning transition plans.
Book of proceedings: 35th AESOP Annual Congress Integrated planning in a world of turbulence, Łódź, 11-15th July, 2023
CC BY 4.0


Ball Talk - March 28 Chitrangada Singh MS Dhoni Divya Dutta Ball Talk - March 27 Zoe Saldana Ball Talk - March 26 Uma Thurman Ball... ...http://www.punemirror.in/entertainment/hollywood/Theyve-got-a-name/articleshow/48734027.cms
Pitt's new drama "By the Sea", will have its world premiere as the opening night film at AFI Festival. The movie will kickstart the festival on... ...http://www.business-standard.com/article/pti-stories/jolie-s-by-the-sea-to-open-afi-festival-115083000370_1.html
By Erin Donnelly of Refinery29 | It was a big year for celebrity relationships in 2005. Jennifer Aniston and Brad Pitt split up. Brad Pitt... ...http://www.msn.com/en-in/lifestyle/relationships/yes-these-celebrity-couples-really-existed-in-2005/ss-AAdKGO3?srcref=rss
has been cancelled. Leonardo DiCaprio, Robert De Niro, Brad Pitt, and Scorsese star in the film, which casts the high-wattage actors as themselves... ...http://www.business-standard.com/article/pti-stories/venice-film-festival-premiere-of-scorsese-s-short-cancelled-115083000191_1.html
18 am New York, Aug 29 ( ANI ): If you are still wondering what's the reason behind Angelina Jolie and Brad Pitt 's house hunt in London... ...http://www.aninews.in/newsdetail5/story230998/angelina-jolie-house-hunting-in-london-to-pursue-politics.html
Brad Pitt sex tape
brad pitt diet routine fight club
William The actor-brad pitt, who will...
These types of Useless Don't Wander,...
World War Z. Ending: How it's Enjoy...


text:
Food Shortages at Russian Grocery Stores as Zelenskyy Deepfake Worries Experts
Western sanctions against Russia are making basic necessities hard to come by. Meanwhile, an expert on deepfakes speaks with Inside Edition after a fake video circulated depicting the Ukrainian president.
Food shortages at Russian grocery stores are leading to fights, as Western sanctions against the country make basic necessities hard to come by.
“There were empty shelves — no salt, no sugar, no pasta,” said a woman who shot video of shoppers scrambling for goods.
A Russian blogger gave a tour of his local supermarket. It was well-stocked, but prices have skyrocketed. Milk is up 45%, pasta is up 30% and fish is up 60%.
Meanwhile, the Kremlin is deploying a new weapon in the war on Ukraine — deepfake videos.
One such video claimed to depict President Zelenskyy telling his soldiers to “surrender” and “give up your arms,” but no one was fooled by such an obvious fake.
“The man’s body doesn’t look like Zelenskyy, his neck doesn’t look like Zelenskyy, his voice doesn’t sound like Zelenskyy and his face just looks kind of odd. But these kinds of deepfakes can fool people, and we need to start getting prepared for how they get improved as well,” deepfake expert Sam Gregory said.
Zelenskyy responded quickly to the deepfake, telling his people there will be "no surrender."
“The only ones who should give up arms are Russian soldiers,” he said.
Arnold Schwarzenegger reached out to his fans in Russia in a video message telling them not to fall for Putin's propaganda.
“To the soldiers who are listening to this, remember that 11 million Russians have family connections to Ukraine, so every bullet you shoot, you shoot a brother or a sister,” Schwarzenegger said.
Trending on Inside Edition
Tennessee Nurse RaDonda Vaught Sentenced to Probation, No Jail Time for Fatal Medication ErrorCrime
Strangers Band Together to Help Unconscious Driver Drifting Into Oncoming TrafficHeroes
Two Suspects Criminally Charged in Florida After Boat Balloon-Popping Video Goes ViralCrime
Police Release 911 Audio of Shannan Gilbert the Night She Went Missing in Gilgo Beach 12 Years AgoCrime
Woman Accused of 'Gaslighting' Husband Into Thinking He Was Senile to Steal His FortuneCrime


text:
Swinging garden chairs, wicker swing chair with stand. Indoor swing stand indoor swing stand chair and hammock c. Black solid steel c frame chair hammock stand construction. Hanging chaise lounger air porch hammock swing chair. Outdoor indoor swing hanging chair with stand patio swing. 12 best of outdoor swing chair with stand. New hanging chaise lounger chair arc stand air porch swing.
Upholstered rocker with ottoman kids rocking chairs at. Outdoor folding chairs : target. Upholstery service for chairs with slip seats. Spindle chair designer, cafe, office, creative. Sturdy dining chairs counter height finish:mahogany. Top 10 best nursery gliders rocking chairs heavycom. Vento loose cover high back fabric dining chair from. Kitchen stools with backs contemporary wooden upholstered. Best chair in the world, zero gravity chair costco zero. Kaikoo faux leather football bean bag chair reviews. Indoor outdoor wicker bar stools with backs counter height.
Target zero gravity chair girls white sandals. Ebel geneva woven swivel recliner chair ash outdoor. Gray woven all weather wicker andalusia outdoor chair. Tween chair sleeper rustic kids sofas by hedgeapple. Garden patio all weather black wicker bistro chair. Gravity free chair with amazing armrests kitchens inspiration kitchens inspiration. Modrn scandinavian nassau outdoor woven lounge chair with.

domain: design


text:
Pet Lovers Gentle Care Dry Bath
Pet Lovers Gentle Care Dry Bath 200ml is an extra mild cleansing formula. It takes care of your Poochâs hygiene needs. In fact, it is most suitable for puppies and small breeds. Likewise, Pet Lovers Gentle Care Dry Bath is made by Pet Lovers. A company which offers a wide range of premium quality grooming products. Also, it consists of non-toxic and natural ingredients which are eco-friendly and safe for the pet. Therefore, the tearless shampoo is great for dogs with delicate skins; the extra gentle composition can be used frequently. Hence, Pet Empire presents a unique formulation to give quick and effective cleansing to your canine. The water less formula is pH adjusted and consists of no preservatives or foaming agents like Parabens and sulphates.
Pet Lovers Gentle Care Dry Bath is made from high-quality ingredients which are blended together to provide a safe and effective bath. It is the best solution to keep the dog clean and well-sanitized between baths.
Pet Club India is an online pet shop that offers all the quality important dog accessories products like dog foods and dog toys. Pet Club India really cares for your love pet dogs, so we deliver the different dynamic products at your door steps without creating your much hassle and delivered specific time given. It also covers all important dog toys & dog foods products on demand with the help of highly expertise supply chain. In particular, they deliver all the useful products of highly reputed brands on your demand. You can different dog products as per the age and breed of your dogs.
- Pet Lovers Gentle Care Dry Bath is made from high-quality ingredients which are blended together to provide a safe and effective bath. It is the best solution to keep the dog clean and well-sanitized between baths.
- Removes dirt, grime and odor.
- No preservatives and foaming agents is added in this shampoo.

domain: pet


text:
Trevor Gott is the leading candidate to head the Angels' closing committee for the remainder of the season, Jeff Fletcher of the Orange County Register reports. The Angels, who find themselves a half game behind the Astros in the AL wild-card race, will now have to make do without their closer, as Huston Street suffered what appeared to be a serious groin injury after he needed to be helped off the field in the ninth inning of Saturday's contest. Manager Mike Scioscia mentioned the Angels would likely go with a committee approach to the ninth inning, Gott should rank as the team's top option after emerging as a key setup man for Street in recent weeks. The 23-year-old has posted a 3.07 ERA across 44 innings with the big club this season, although it has come with a rather middling 25:15 K:BB ratio. Along with Gott, look for Fernando Salas and Mike Morin to fill vital roles at the back end of the Angels bullpen.
The Angels activated the following players from the disabled list: Collin Cowgill, Taylor Featherston, David Freese, Matt Joyce and Cory Rasmus. Freese will start in Tuesday's contest. Moreover, the team called up Jett Bandy, Michael Morin, Nick Tropeano and Wesley Wright. The team also designated Alfredo Marte and Drew Rucinski for assignment.
The Angels optioned right-handed pitcher Mike Morin to make room for Thursday's starter Nick Tropeano on Wednesday, per the Orange County Register. Tropeano will face the White Sox in a late game Thursday. He is 1-1 with a 3.00 ERA in 12 innings this season. Morin had a mediocre 7.43 ERA in 23 innings for the Angels before the demotion.
The Angels have promoted shortstop Ryan Jackson and relievers Cam Bedrosian and Mike Morin in a flurry of moves Sunday, per the Orange County Register. Jackson has just two hits in 24 major league at-bats with no plate appearances this year. Bedrosian had been demoted last week after allowing 23 hits in 19 innings and a 4.74 ERA this season. Morin has been worse in 2015 despite appearing in 29 games. He owns a disturbing 7.43 ERA.
The Angels are sending reliever Mike Morin down to Triple-A, per the Los Angeles Times, giving the team an open roster position. In 29 contests for the Angels, Morin was 1-1 with a 7.43 ERA, including a disastrous outing Tuesday in which he allowed four runs and five hits.


text:
Oto’s donor score, recipient variables and procedure characteristics were not statistically linked to PaO2/FiO(2) at the sixth post-operative hour. Ischaemic time of the last implanted graft and the lactate level at the end of the procedure are the only factors related to Grade III PGD in this group.\n\nHyperlactataemia most probably reflects the severity of early PGD, which leaves graft ischaemic time as the only factor predicting early PGD in a multicentre population of cystic fibrosis lung graft recipients.”
“Background: CF infants may be at increased risk of sodium depletion
which may lead to impaired growth. The screening assay objective of this study was to evaluate their sodium supplementation requirements.\n\nMethods: Ten CF infants had serial measurements of weight and plasma/urine sodium and creatinine. Sodium supplementation was adjusted with the aim of maintaining fractional excretion (FENa) between 0.5% and 1.5% and urinary sodium > 10 mmol/L.\n\nResults: BLZ945 purchase Urine sodium:creatinine (UNa:Cr) ratio strongly correlated with FENa [UNa:Cr (mmol/mmol)=35.0 x FENa (r=0.99)]. The FENa target range corresponded to UNa:Cr 17-52 mmol/mmol. All infants required sodium supplementation to achieve UNa:Cr > 17 mmol/mmol. Sodium Supplement requirements (mean +/- SD) at ages 0-3, 3-6, 6-9 and 9-12 months were 1.9 +/- 0.5, 1.8 +/- 0.8, 1.9 +/- 0.9 and 0.8 +/- 0.4 mmol/kg/d. No infant required caloric supplementation to achieve
expected weight gain.\n\nConclusions: Using current UK guidelines, many cases of sodium depletion may be overlooked. Some infants require more
than the recommended 1-2 mmol/kg/d. UNa:Cr ratio is a useful non-invasive measure to monitor sodium supplementation. (C) 2009 European Cystic Fibrosis Society. Published by Elsevier B.V. All rights reserved.”
“Upon infection, the genome of herpes simplex virus is rapidly incorporated into nucleosomes displaying histone modifications characteristic of heterochromatic structures. The initiation of infection requires complex viral-cellular interactions that ultimately circumvent this repression by utilizing host cell enzymes to remove repressive Navitoclax Apoptosis inhibitor histone marks and install those that promote viral gene expression. The reversion of repression and activation of viral gene expression is mediated by the cellular coactivator HCF-1 in association with histone demethylases and methyltransferases. However, the mechanisms and the components that are involved in the initial repression remain unclear. In this study, the chromatin remodeler chromodomain helicase DNA binding (CHD3) protein is identified as an important component of the initial repression of the herpesvirus genome. CHD3 localizes to early viral foci and suppresses viral gene expression. Depletion of CHD3 results in enhanced viral immediate early gene expression and an increase in the number of transcriptionally active viral genomes in the cell.


text:
[dropcap style=”font-size:100px;color:#992211;”]T[/dropcap]he interplay between fantasy and science has frequently led to great strides in popular culture; Soviet Space Graphics, coming out of the unique environment of the former USSR, provides for a particularly interesting seam which has a genuinely distinctive landscape all of its own.
In the introduction to this compendium of twentieth century science and science-fiction artwork, author Alexandra Sankova describes the all-encompassing, forward-looking, endless questioning which categorised 1950s/60s attitudes in the USSR towards space travel; this of course gave way to the fractious ‘space race’ between the US and the USSR, but before that point, space travel’s possibilities instigated a new kind of popular science, aimed at all ages and all walks of life. Ideas about accessibility, the range of new developments and the scope of Russia’s political might inspired notable titles like Science and Life, and Knowledge is Power. As the timeline of events in the USSR came to encompass great milestones like Sputnik, Laika the dog and the successful space voyage of Yuri Gagarin, it must have felt more and more like life imitating art, and no doubt these successes helped to stoke the creation of more public interest and even more appetite for this kind of reading material.
The rest of the book consists of colourful examples of the art which underpinned titles like Science and Life. These are fascinating; there’s a real benefit to seeing these illustrations as an outsider, as (in these exhaustive qualities at least) this is still an unknown and unappreciated visual culture in the West, as alien in its own way as the cosmic sights it attempted to capture. Taking the form of diagrams, sometimes to blueprint-levels of detail, speculative art (what could be achieved) and illustrative art (accompanying anything from sci-fi fiction to scientific articles), the images are very striking and imaginative, going so far as to show human cities in orbit around different stars — ah, the joys of boundless optimism. The visuals are all helpfully captioned, too, with attributions and descriptions of what each artwork depicts.
The book is chaptered and these chapters include: Exploration; Cosmic Pioneers (chock-full of industry and heroism), Future Visions (which is probably the most intriguing section of the lot) and finally, Alternative Worlds. Then there’s one last section containing information on the magazines, biographies of notable contributors, and an index.
It is highly unlikely that a collection of this nature will be seen again in such a comprehensive format, or curated with this evident knowledge and interest. This is a good book in which to get lost, marvelling at a time when whatever was plausible was seen as achievable. In that respect, the attitude behind this hitherto-unknown world of science and culture is every bit as charming as its art.
Keri can usually be found contributing to Reprobate Press, where she covers a bit of everything, or writing and editing Warped Perspective, a website which features cult film, TV, art and books.


text:
Options with increasing volume: TGTX VMC ULTA ZUMZ FNSR JBLU BP SLC GOOGL CVX.Also On Yahoo Autos Finance Games Groups Health Maps Movies Music omg.Windows 2000 includes a new feature that allows you some interesting management options concerning drive letters.
There are always the same number of positions on either side of the open transactions.Command-toets tijdens slepen: Het gesleepte onderdeel verplaatsen.Increasing open interest means that new money is flowing into the marketplace.Get the options volume and trading data you need to make informed decisions.One complication involved when looking at the overall level of open interest in a futures market is the impact of deliveries.
The Options Industry Council (OIC)Quotes and other information supplied by independent providers identified on the Yahoo.
Volume icon disappeared from my system tray, and the
Video Option volume 139This page includes last sale price, share volume, and percent changes of.CONTENTS BUDGET OPTIONS, VOLUME 1: HEALTH CARE VII Options The Private Health Insurance Market Option 1.
Binary Options Trading Based On Volumes •
Options analysis software from Livevol provides Real-time options and equity quotes, trades, calculations.
Arca Options - New York Stock ExchangeSimilarly, an increase in open interest along with a decrease in price confirms a downward trend.New option traders are sometimes confused by option-trading terminology.Use these options to control the behavior of your Volume Axis field.Open interest and volume are two closely related topics in the world of options trading, so it makes sense to discuss them as a.
Option | Wireless TechnologyOptions volumes for the day are displayed for the top twenty symbols with the highest volumes.
Volatility Information Trading in the Option Market SOPHIE X. NI,. from close option volume, indicating a higher informational content for the open volume.What links here Related changes Upload file Special pages Permanent link Page information Wikidata item Cite this page.
Does a large open interest with zero volume in an optionOCC offers comprehensive options and futures volume in a variety of formats.If both parties in the transaction are closing positions then the open interest decreases accordingly.This web site discusses exchange-traded options issued by The Options Clearing Corporation.No statement in this web site is to be construed as a recommendation to.Home Mail Search News Sports Finance Celebrity Weather Answers Flickr Mobile More Politics Movies Music TV Groups Style Beauty Tech Shopping Try Yahoo Finance on Firefox.
Open interest can help you determine whether there is unusually high or low volume for any particular option.
Volume provisioning options - library.netapp.com
Volume, volatility and open interest leaders. Quotes are real-time for NASDAQ, NYSE, and NYSEAmex when available.We carry end of day historical option prices history for all U.S. Equity options. bid, ask, volume and.Every now and then we are looking at trades and see some unusual and abnormally high options trading volume.
Research Options Overview: Fidelity Investments
If you are using Snapshot autodelete, you also need to set volume options related to.Price movements in the options market result from the decisions of millions of traders.Analogously, declining open interest implies that the market is liquidating, and suggests that the prevailing price trend is coming to an end.

domain: finance


– Regarding the TNA lawsuit against WWE, there was no financial settlement because TNA just dropped the case. Both sides agreed to pay their own legal costs.
– On a related note, the TNA lawsuit was the hold-up on WWE signing El Generico. WWE was about to sign him last June but they learned he had done two tryout matches with TNA in 2011. Generico got the phone call from WWE around the same time Ric Flair did. No word yet on what Generico’s gimmick will be or if he will lose his mask. He began working in developmental on February 4th.
– Nothing is official yet but people within WWE expect Lita to induct Trish Stratus, Bret Hart will induct Bob Backlund and Jim Ross will induct Mick Foley into the WWE Hall of Fame this year.


The latest transfer rumors from around the footballing world, including Premier League, La Liga, Serie A, Bundesliga, Ligue 1, and much more.
Ancelotti wants to sign Werner from Chelsea
Timo Werner has emerged as a summer transfer target for new Real Madrid boss Carlo Ancelotti.
Despite only signing Werner last summer for €53 million from RB Leipzig, Chelsea are allegedly not against the idea of selling him for an affordable price. Therefore, Ancelotti is encouraged and would welcome the versatile forward to Real Madrid.
Lyon playmaker Houssem Aouar is another player that is on the Real Madrid manager’s radar.[Fichajes – in Spanish]
Sterling to replace Dembele at Barcelona?
With only a year left on his contract, Ousmane Dembele’s Barcelona future is under a cloud. Talks for a new deal have made little progress. The Frenchman’s situation has even reportedly captured the interest of Paris Saint-Germain.
Should Dembele leave, Barcelona believe Raheem Sterling could be an ideal replacement. The Manchester City winger may be open to a Camp Nou move after struggling to win over Pep Guardiola last season. [Sport]
Leipzig star Adams on Arsenal’s radar
RB Leipzig full-back Tyler Adams has emerged as a potential transfer target for Arsenal.
The Gunners, who could lose Hector Bellerin this summer, are searching for a new right-back. Adams is a player that interests them, but Leipzig are reluctant to part with the 22-year-old American. [The Athletic]
Manchester United shortlist three Sancho alternatives
Signing Jadon Sancho from Borussia Dortmund this summer is Manchester United’s transfer priority.
But if the 21-year-old doesn’t arrive, the Red Devils will turn their attention to signing either Chelsea’s Callum Hudson-Odoi, Barcelona’s Ousmane Dembele, or Juventus’ Cristiano Ronaldo. [Express]
Arsenal close in on a deal for Onana
The Gunners are close to completing a deal to sign Ajax goalkeeper Andre Onana.
Despite having not agreed on a transfer fee with Ajax yet, Mikel Arteta’s side are confident. Onana is seen as a replacement for the club’s first-choice keeper Bernd Leno. Although the Cameroonian is still serving a 12-month ban from football after breaching doping regulations.
Pending the result of an appeal, Onana may have to wait until January or next summer to complete his Arsenal transfer. [Football London]


text:
A man driving a moped was killed Saturday night in an accident near Angola.
According to a news release from the Steuben County Sheriff's Department, emergency crews were called just before 10:30 p.m. Saturday on a report of a vehicle crash on County Road 200 West just north of US Highway 20.
Upon arrival, investigators determined a southbound car driven by Robert Watson, age 38, of Angola, collided with a northbound moped driven by Duane Boyles, age 65, of Angola.
Reports indicate that Boyles was pronounced dead at the scene by the Steuben County Coroner’s Office due to traumatic injuries. Boyles was not wearing a helmet.
Watson was uninjured in the crash.
Authorities report that it is unknown at this time if alcohol or drugs are a factor in the incident. The crash remains under investigation.
Assisting at the Steuben County Sheriff's Department at the scene were the Angola Police Department, Angola Fire/Rescue, Steuben County Coroner’s Office, and Steuben County EMS.
(07-20-2019) Stoy Crowned 2019 Miss Steuben
(07-19-2019) Private Sector Employment Reaches Preliminary Record Peak
(07-19-2019) Six States Unite for Move Over Law
(07-19-2019) Montpelier Bean Days Balloon Fest This Weekend
(07-19-2019) Cooling Centers for the Steuben County Area
(07-19-2019) Woman Arrested for Dealing Meth
(07-19-2019) Opening Events Friday at the Steuben County 4-H Fair
(07-19-2019) Bronson Polish Festival Holds Opening Ceremony
(07-19-2019) Arrest Warrant Leads to Additional Charges
(07-19-2019) Sturgis Men Arrested Following Police Pursuit
(07-19-2019) The Heat is on for Friday with High Heat Idices
(07-18-2019) Indiana BMV Issues Refunds
(07-18-2019) Michigan Seat Belt Use Is Up In A Big Way
(07-18-2019) Michigan's Jobless Rate Unchanged In June
(07-18-2019) Acquifer Opponents Face Set Back In Williams County
(07-18-2019) Defiance Arson Trial Continues
(07-18-2019) Man Sentenced To 17 Years In Toledo For Attempted Murder
(07-18-2019) Maumee Man Faces Burglary and Assault Charges