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Our dog is a German shepherd named Lady. Laura has kept our dog several times and our dog loves staying in her home. Lady loves Laura's two dogs Chad and Bentley. They all play so well together. Lady loved being with Laura because Laura treats your dog as one of her own. Any time we said we were going to go see the boys which are Chad and Bentley Lady always got very excited. If you want someone to take care of your beloved dog like we do, then take them to Laura's home. It's an experience your dogs will never forget.
Luke and Lolly love going to Roeslers Kennels, its their home away from home, Prices for my 2 German Shorthaired pointers is only $15 a day compared to $50 a day anywhere else. great savings and just as much care if not more
Carole is amazing! She was fabulous with our cat and she has a natural understanding and relationship with animals and people. I felt very comfortable with her being in my home and feel like she could be a family member to me already! Could not have had a better experience!
Connie is fantastic! Her love for dogs shines through everything she does, and I'd trust her again with my dogs in a heartbeat. Her business is set up for proper and loving care of dogs of all sizes. She cares about each dog's health and well being, and we enjoyed the bonus, unofficial socialization 'training' that our dogs received with both people and other dogs. It was also easy to plan for a trip as all we needed to pack for the dogs was their food; Connie takes care of the rest. And knowing my cuddle dogs would still get their cuddle time in addition to lots of yard space to run and play helped me feel at ease in leaving them. If you need a place to board your dog for overnight stays or just for the day, WoofWoof is the place to go! Additionally, there is a dog grooming facility on site. Dawn is sweet, thorough, and made our dogs look like they were ready for a show. Best grooming and nail trimming service we've ever had, and at a great, reasonable price. My dogs might actually enjoy the experience now!
Wags is perfect for days when I have to work a little longer than usual, and the dog needs a little break from being home alone. The walkers are professional and courteous, and always leave a note detailing the walk, which is very helpful. My dog goes a little nuts around other dogs, so he can't really go to daycare, and Wags is the perfect solution! I would recommend them to anyone looking for a trustworthy and reliable dog walker. Plus, they are one of the only services in the area with online booking.
Jen is great!! I never worry about leaving my pup in her care and I always come home to the house looking even better than when I left. I have recommended her to many of my friends and co-workers and they have all been just as happy as I am. Jen at Baby Your Pet offers a great service at a great value!
Connie was great! Very happy with the whole pet sitting experience. She is so sweet with my two cats. One needs insulin shots twice a day & she provided the extra TLC needed. She also responded very quick with her quote & is very easy going to talk with. I would definitely recommend her & will hire her again in the future :)
I have used NLN for puppy classes and the day training program. They exceeded my expectations and I have been a loyal client of their other services too. I really enjoyed that the trainers seemed to actually care about my dog and how we were progressing each day. I recommend them to anyone.
We have used the Petsitter several times. She feeds our cat each day, cleans the used pet dishes, and cleans the dirty box. She even took a picture of the cat one day and sent it to us!
Brandi did a nail trim on my senior lab, and she was great! She arrived on time, kept my lab calm and comfortable, and the price was fair and affordable. I'll definitely use her again!
Toni has cared for my kitten Lilly's grooming needs since she was born. Toni is very knowledgable and very caring. I would recommend Toni for any ones cats grooming needed and also to purchase a kitten.
We have come to really rely on this great service. We have a very high energy dog and it is simply difficult to find the time to give her all the exercise she needs to be a happy puppy. With Walks In The Parks, Maybelle doesn't get a mere walk--she gets run-around-like-a-wild-animal time with other dogs. (As a side benefit--this has made her much more comfortable with other dogs. She used to be very fearful of them, and a bad experience at our local dog park did not help. Now she is not fearful with new dogs AND she loves the dogs she plays with regularly. This company is owned by an experienced dog trainer--Paddy--and she seems to be really good at preventing conflict between dogs.) She is always SO excited to be picked up by Rick and Paddy and comes back with the dumbest happiest look on her face, it's really cute. Now, we have some friends who rely on doggie daycare to get their dogs the play and exercise they need. I think that's a great option if you're away all day long every day during the work week. But of course with doggie daycare you are dropping off and picking up each day, which adds a significant amount of time to your commute. This service is great because it comes with drop off and pick up. At this point we have worked with Rick and Paddy for so long that they have keys to our house and they can get her and drop her off even when we're not home. Of course we would not be comfortable letting our little girl go off on such outings if we didn't know how much Rick and Paddy care for her! They love dogs and they love Maybelle. (A final side benefit--regular photographic updates of Maybelle showing a fierce side of herself, at play, that we've never seen!)
New To Thumbtack
Are you worried about your dog while you're away at work? Many pet parents worry their dog is bored, not getting enough exercise and/or damaging belongings or furnishings while they're at work. Rosie's Doggie Daycare provides fun cage-free doggie day care that can make a major difference in your and your dog's life. Our day care includes exercise, playtime, fresh air, and an opportunity to build socialization skills and most importantly, a chance to burn off all that pent-up energy! Give your dog something fun to look forward to every day! Our day care attendants have years of dog handling experience and are dog behavior experts -- ensuring that your pet will have a safe, fun, and enriching experience while at Rosie's. Rosie's also features a full-service grooming Salon with highly experienced and gentle groomers. We customize each haircut to your desires and offer specialty services such as creative coloring, de-skunking and FURminator de-shedding. Do you have a dog that could brush up on his/her manners? We offer many training packages and classes with our certified dog trainer. Training enhances communication between dog and owner and can help immensely with problem behaviors.
New To Thumbtack
At the Frolic Inn, we take all the typical kennel services including boarding, day care and grooming, to a new standard of care in a 40-acre environment that is inspiring and sustainable. What's more, we embrace science-based methodologies to develop pet behavior for the benefit of all. In short, we think outside the crate.

domain: pet


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April 6, 2001
Here is the reality of modern agriculture. For every $1 of profit a Canadian farmer makes, taxpayers provide $3.55 in subsidies. In the case of Ontario farmers, taxpayers kick in $6.20 in subsidies. That “very nice living for the farmer” that the George Morris Centre touts for the large-scale farmer is not an honest living. The only reliable economy of size in modern agriculture comes from harvesting subsidies.
Big-is-beautiful advocates like those at the Morris Centre — disdaining the small farmer and dreaming of industrialized agriculture powered by mighty machines — have successfully convinced governments to subsidize large-scale practices. Their experiments at industrial and social engineering — despite decades of attempts — have all failed to be economic. The reason? Large-scale monoculture farming is inherently risky.
Without insurance and other government supports, these growers would be betting the farm on their one crop. In fact, because too much rain, pests and many other hard-to-measure hazards can wipe out an entire harvest, no private insurer has ever been able to provide unsubsidized comprehensive crop insurance. Traditionally, farmers self-insured by planting many crops and otherwise diversifying their operations, imposing natural limits on crop size.
Contrary to the Morris Centre’s assertions, Ontario’s processing tomato-farming sector, which produces tomatoes for ketchup bottles and canning operations, is overwhelmingly driven by the need to manage risk. Ontario tomato farms face much higher risks than farms in California, where rain does not slow down harvesting machines during the time-sensitive harvest, or wipe out a farmer’s harvest, as happened in part of Ontario last summer. The risk of tomato farming in Ontario is so great that the processors — who can’t afford to have their plants idle because a farmer misses a shipment — manage the risk by diversifying the locations of the farms that supply them, and by requiring the farms to maintain surplus capacity in their harvesters. For these reasons, Ontario’s tomato farms operate their equipment just three to four hours a day during the seven-week harvesting season, while California’s run flat out, 20 to 22 hours a day. Because new California-style harvesters can’t be paid for when run just four hours a day, Ontario farmers purchase smaller harvesters or used ones — the ones California tomato growers discard.
If tomato farming in Ontario truly involved little risk, Ontario would be producing many more tomatoes. As it is, Ontario imports two to three times as much tomato as it produces, much of it from California. Canada, in fact, is California’s number one tomato marketing area.
Relatively small-acreage farms can be extremely profitable by serving lucrative niche markets. The many small farms of the greater Toronto area that supply restaurants with specialty vegetables, health food stores with organic herbs, ethnic bakeries with exotic grains, and office buildings with luxuriant plants rival the region’s traditional farms, and together they now produce 67% more farm output than Prince Edward Island and 80% more than New Brunswick. Unlike mechanized industrial farms that primarily produce low-value commodities for export markets, and that must compete against countries with longer growing seasons or cheaper labour, the smaller farms serving local niche markets face little competition from distant producers, making them viable without subsidies. Rather than sustain agriculture, the subsidies only distort the agricultural sector away from innovation and entrepreneurship.
There is no glory in running large machines, new or used, and there is no shame in managing labour-intensive operations, as do farmers who serve the demand for fresh fruits and vegetables, and for many specialty markets. But there is value in being innovative and entrepreneurial, as small-acreage farms tend to be, and there is status in being off the dole.

domain: economics


text:
The Adventure Annual by Various
The Adventure Annual By Various
Illustrated by Various
The Popular Press Ltd, 1954
Edition not specified
Book Condition: Fair.
Jacket Condition: no DJ
Photographs form part of the description, so please view all images carefully. If you would like more information on what our book gradings mean, see here. If you need any further details, please ask.

domain: hobby


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Though online dating is still unorthodox to many the online dating site for millennial muslims in america with few muslim acquaintances to relate her. Muslim dating at muslimacom sign up in a misunderstanding of what online dating is muslim online dating opens up a whole new a girl aged 23 years old. The guide to dating a muslim girl islam is in fashion while the word “terrorism” seems to be the first that comes to mind when you hear about muslims. Santaquin's best 100% free online dating site meet loads of available single women in santaquin with mingle2's santaquin dating services find a girlfriend or lover in santaquin, or just. Muslim dating is not always easy – that’s why elitesingles is here to help meet marriage-minded single muslims and find your match here.
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domain: sociology


text: Vacation is all Burt County ever wanted! Most of those who voted in the last poll said they had springtime plans to get away and go on a vacation! Where will you go? Will you travel overseas? Will you enjoy a staycation closer to home? Vote below to share with us!

domain: travel


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|While not the best rated game in November, The Legend of|
Zelda: Tri Force Heroes entertained regardless.
PictoParty (Wii U eShop) - B-
Dynasty Warriors: Gundam 3 (PS3, 360) - D
Word Party (Wii U eShop) - C
Dragon Ball Z: Extreme Butoden (3DS) - B-
The Legend of Zelda: Tri Force Heroes (3DS) - C+
Typoman (Wii U eShop) - C-
|There were a good amount of turkeys review-wise this month,|
but Dragon Ball Z: Extreme Butoden was not one of them.

domain: game


text:
Episode 7 – Musicians find music. Stories from musicians Johnny Goudie and Ellen Foley about “first times” in their musical lives.
Johnny Goudie – I Want You to Want Me/Cheap Trick
“I was thirteen. And no one told me I was gonna be taking 17 showers a day that took 30 minutes at a time.”
Ellen Foley – Guilty/Randy NewmanPodcast, Uncategorized and tagged cheap trick, ellen foley, johnny goudie, randy newman. Bookmark the permalink.

domain: artistic


EITAN ABRAMOVICH / AFP / Getty Images
For most farmers, their day-to-day duties consist of tending to their land and knowing how to reap the most from their crops. While these agriculture experts are used to checking on the daily progress on their farms, they sometimes come across extraordinary finds that are completely unexpected. Such was the case for one unsuspecting farmer who happened to come across a mysterious object that turned out to have belonged to something completely unexpected–something that went extinct many years ago. Keep reading to find out what the farmer’s bizarre discovery actually turned out to be. Believe us, you don’t want to miss it!
1. A Christmas Surprise
Farmer Jose Antonio Nievas was just getting some fresh air while enjoying a casual Christmas Day in 2015 stroll along his grounds when something unusual happened that would forever be ingrained in the memory of those far beyond his small town.
Edwin Remsburg / VW Pics via Getty Images
The farm was a common place to find various kinds of plants and animals, but on that unassuming day, Nievas stumbled across something that he had never encountered in his line of work and completely left him in a state of shock and wonder.
2. Finding a Foreign Object
Jose Antonio Nievas’ farm was located in Carlos Spegazzini, a city about located 25 miles (40 km) south of Buenos Aires. It was during his stroll when he passed a stream on his property and something striking caught his eye.
Ruptly / Youtube
Unassumingly wedged in the bank of the stream was a large, rounded object that he initially thought looked like a giant stone. However, as he approached the item, he realized that it was in fact not a large rock.
3. Not What it Seemed
As he got closer, Nievas observed that it was in fact not a stone at all. The strange object was partly covered in mud and he couldn’t determine what it was. As he tried to clear the grime off of the round object, he started to associate it with something else.
4. Calling for Assistance
Nieves attempted for some time to dig the mystifying object out of the mud and clean it to get a better look. Nonetheless, he was having trouble dislodging it from the riverbank and needed another pair of helping hands to assist.


text:
Retirement Plan Detectives
A couple become Retirement Plan Detectives, searching records from old employers.
Have A Question About This Topic?
Taking your Social Security benefits at the right time may help maximize your benefit.
At what point can you call a personal vehicle commercial?
What’s the deal with your yearly free credit report?


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There are a lot of great online casinos out there, but which is the best for Malaysian players? In this article, we have outlined some of the most popular Malaysian online casinos and their current promotions. Whether you’re looking for a no-download casino with top-notch mobile support or a high-stakes casino that offers unique games and bonuses, we’ve got you covered. Gaming is one of the most popular activities on the planet, and in Malaysia, it’s no different. From hardcore slot machines to more exotic games like baccarat, casino rewards programs are a big part of the scene. In this blog post, we will take a look at some of the best casino rewards programs in Malaysia and what they offer players.
We’ll also provide tips on how to get the most out of them and which ones are best for you. So whether you’re looking for some extra spending money or just want to enjoy your favorite games even more, read on to learn more about the best casino rewards programs in Malaysia. Loyalty programs – These reward frequent players with exclusive deals and privileges, such as free drinks or meals. Cashback programs – Players receive a percentage of their total wagers back in cash, which can be used to purchase casino goods andservices. Slot tournaments – Held periodically, these offer players the chance to win large prizes by playing in specific slots machines during designated periods of time.
One of the best ways to earn rewards points or bonuses slot gacor mudah menang at a casino is by playing specific games. In general, most casinos reward players with points for using their credit or debit cards, making deposits, and making real-money bets. Players can also earn free play rewards when they first sign up and make initial deposits. Once you have earned a certain number of points, you can redeem them for cash or other rewards. Many casinos also offer exclusive bonus offers and tournaments that are only available to registered players with a certain level of rewards points. Malaysian players can enjoy some of the best rewards programs in the world thanks to the country’s renowned casino operators.


Primal RC is proud to introduce the 1/5 Scale Quicksilver Ready to Run Brush-Less Electric powered Dragster!
We hope that its High quality parts, performance and good looks will give you many hours of exciting tire shredding, asphalt burning RC Dragster Racing Fun!We used lots of CNC aluminum and carbon fiber parts to make this a strong, reliable, fast machine while keeping the weight down.
Please note: This dragster comes with a Clear Strong Polycarbonate Material, pre cut, ready to be painted body on it and not the black body that is shown on the ad. It also comes with black rear rims instead of the chrome ones pictured and a few red anodized parts like the brake calipers and throttle servo horn.
- Carbon Fiber Lower frame plates, front lower wing mount and rear wing sides
- 960KV 3500KW 8 Pole Brush-less Motor
- 200 Amp Waterproof Speed Control with built in BEC
- High performance modified 8000 RPM clutch for great launches off the starting line
- 17 tooth steel pinion gear and 54 tooth nylon spur gear for good overall speed and acceleration
- Large rear high traction white letter belted drag racing tires with medium compound foams
- Chrome plated rear heavy duty nylon rims with aluminum bead-locks and steel 24mm hex inserts for added strength
- Chrome plated front wheels with straight ribbed racing tires
- Oversize rear adjustable aluminum wing with carbon fiber sides
- Light weight Front Polycarbonate wing with carbon fiber mount
- Strong Plastic roll cage and Polycarbonate body shell
- Dual Rear mechanical disc brake system with carbon fiber rotors
- Ball bearings used throughout the entire vehicle
Brush-less Dragster Special Features
- 2.4 ghz 3 channel computer radio that features include:
- 4-AA Battery holder for light weight and improved balance
- Easy to read LCD screen
- 300 Meter max range 10 model memory
- Servo reversing on all channels
- Dual rate steering
- End point adjustment on all channels
- Exponential steering and throttle
- Digital trim display
- Servo sub-trim for steering and throttle
- 3 character model naming
- Low battery memory retention
- Built in Fail-safe
- Low voltage alarm.
- 20KG All metal gear servo for precision steering
- 20KG All metal gear brake servo
- Centrifugal Clutch Power Take off system for persise quick powerfull launches off the line
- Has reverse! Unlike the gas powered Dragster
- 8S Lipo Battery Ready (2 -4S batteries recommended) a total of 29.6 Volts!
SpecificationsSkill Level AdvancedSpeed 70+ MPHLength 61 inchesRTR Weight About 24 poundsHeight 15.25 inchesWheelbase 48.25 inchesFront Tires (pre-glued) 3.25 x 2.125 inchesFront Wheels 2.375 x .875 inchesFront Track 7 inchesRear Tires (beadlock) 7.25 x 4 inchesRear Wheel Outer Diameter 4.75 inchesRear Wheel Inner Diameter 5.5 x 3.5 inches wideMinimum Ground Clearance 0.5 inchesRear Track 17.25 inchesFront Track 7 inchesMotor
- Aluminum Main frame brace for strength and rigidity.
- CNC Aluminum parts throughout the entire vehicle!
- CNC Aluminum 3 Piece transmission with Steel gears and Locked Axle.
- CNC Aluminum Axle tubes, supports and hubs
- CNC Aluminum locker with steel gear installed
- CNC Aluminum rear upper and lower main Chassis.
- CNC Aluminum upper brake pad support
- CNC Aluminum rear wing supports and mounts
- CNC Aluminum spur gear plate and cover
- CNC Aluminum enclosed clutch brace
- CNC Aluminum motor mounts
- CNC Aluminum chassis connector
- CNC Aluminum front skid plate and chassis protector
- CNC Aluminum Ball bearing push-pull steering system
- CNC Aluminum front axle supports and hubs
- CNC Aluminum rear inner and outer Tire Bead-locks and enclosed wheel nuts
- CNC Aluminum rear brake calipers and linkages
960KV 8-Pole BrushlessESC
200A Waterproof Transmission Single SpeedDifferential Type LockedBrake
Rear Mechanical Disc Brakes Drive System 8000RPM centrifugal 2 Shoe racing clutch, All Steel Gears with 1 Nylon Spur GearSteering Push / Pull design with CNC Aluminum, Ball Bearing SupportRadio 2.4 Ghz, 3 Channel Digital RadioServos Torque: 20 KG, Speed 0.12 sec/60 degrees(6.0V)Battery Tray 140mm x 85 mm with hook and loop style holding straps
Needed to complete:
2-4S LIPO Batteries (5000mah 30C or more) with 6.5mm connectors
Battery Charging Equiptment
4-AA Batteries for Transmitter
Primal RC Wheelie Bar (PRQS0001) Highly Recommended
Everything in pictures is Included!


Red Rocks Amphitheatre | Morrison, Colorado
As the multi-platinum trio WALLOWS announces their world tour in support of their new album Model, the alt-rock scene is gearing up. This tour is their biggest one to date!
In support of their much anticipated album - Model - the band is going on their 2024 WORLD TOUR and we’re sure you’re all jumping up and down with excitement!
And isn’t Red Rocks Amphitheatre in Morrison, Colorado just the perfect venue?!
Behold! This stage will be taken over by the one and only Wallows on September 5, 2024, Thursday!
Amazing band. Amazing music. Amazing performance under the amazing night sky. What else could you possibly want more of a concert?
How about an amazing opening act? Yes! Benee is joining them on this show!
So what are you waiting for? Click the GET TICKETS button now before it’s too late! Fans all over are rushing to get the best tickets and VIP packages to this concert! You wouldn’t want to miss out!
Wallows, the alt-rock upstarts, are going on their largest tour to date this summer. 38 cities, y’all!!!!
The tour is in support of their much awaited album - Model.
Throughout North America, Europe, and the UK, the band will be performing in the biggest rooms they have ever played during their global tour. The tour concludes on October 22 at Alexandra Palace in London, United Kingdom. It begins on August 6 at Alaska Airlines’ Theater of the Clouds in Portland, Oregon.
The news of the tour comes after Wallows made a spectacular comeback last month with the release of "Your Apartment," the lead single off their upcoming album Model and their biggest-ever streaming debut. The release date of "Calling After Me," the second single, is set for March 21. You can already pre-order/pre-save the John Congleton-produced album, and it will be released on May 24th via Atlantic Records. The model will be physically available on CD, clear cassette, limited edition "sunset" vinyl (a three-color mix of lemon, tangerine, and apple), and regular clear vinyl only through Wallows' web store.
Wallows was also very creative in how they announced their tour. They announced the news of a worldwide tour along with a short film featuring all three members and Benee, who will open for the band on their North American tour.
Dylan Minette says, “I can confidently say this is the first time that I’m really anticipating a tour announcement. I’m more nervous than ever — but not in a negative way. I know it’s going to go well. I know our fans show up but I haven’t been able to stop thinking about it every day.”
Since they were eleven years old, Dylan Minnette, Braeden Lemasters, and Cole Preston make up Wallows. Nearly two decades ago, they started performing music together on the LA music program Join the Band, and they haven't stopped since. The group released Tell Me That It's Over, their sophomore album, in March 2022. Ariel Rechtshaid, a three-time GRAMMY Award winner (Vampire Weekend, Haim, Adele), produced the record. Wallows continued their constantly changing path of sound experimentation, combining a wide range of musical concepts into their own unique creative vision, ranging from lo-fi post-punk and indie-folk to early '90s dance-pop psychedelia.


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This fire (now controlled), threatened Canada's largest First Nation & a Nat'l. Park. Parks CA photo.
Thursday, 14 April 2011
Earth to EPA: Bees Need Help Now
PANNA - Apr 14 '11
In the last four months, 1.2 million people around the world have raised their voices on behalf of honey bees – urging officials to take decisive, precautionary action by suspending a suspect class of pesticides (neonicotinoids) known to undermine honey bee immunity. Details here.

domain: news


text:
We have the important responsibility of providing our customers with trustworthy intelligence to help them transform the world for the better. The need for high-quality data from rigorously selected sources is becoming ever more important as the scholarly record becomes increasingly polluted.
A trusted record of research is essential for the global R&D community to effectively use published research outcomes to elevate ideas that will benefit everyday life. The responsibility for protecting the integrity of the scholarly record is shared by all those involved in the creation, delivery and assessment of academic literature, and we take our part in that collective responsibility very seriously.
The quality of the content we accept into the Web of Science Core Collection™ is paramount to us. As the creator of the world’s leading publisher-independent global citation database, we remain true to our long heritage of objectivity, selectivity and collection dynamics, while adapting to changes in the research ecosystem and the scholarly publishing landscape.
Responding to changes in the publishing landscape
We apply stringent standards and use transparent selection criteria to select new journals, books and conference proceedings for coverage in the Web of Science. Only a fraction of journals pass our quality criteria (less than 15%).
Still, Web of Science coverage increases overall every year, reflecting the growth in global research output. Journals evolve their scope, reset their editorial thresholds, refresh their editorial boards and change ownership; each of these can affect a journal’s characteristics and the quality of its published content. Acceptance into the Web of Science does not guarantee permanent indexing – we periodically re-evaluate journals to ensure the content continues to meet our selection criteria. Any journal that no longer meets our quality criteria is removed from coverage.
We have always been responsive to community and customer feedback when prioritizing which journals to re-evaluate. In recent months, we have taken additional proactive steps to counter the increasing threats to the integrity of the scholarly record. We have invested in a new, internally developed AI tool to help us identify outlier characteristics that indicate that a journal may no longer meet our quality criteria.
This technology has substantially improved our ability to identify and focus our re-evaluation efforts on journals of concern. At the start of the year, more than 500 journals were flagged. Our investigations are ongoing and thus far, more than 50 of the flagged journals have failed our quality criteria and have subsequently been de-listed.
The geographical spread of the de-listed journals is wide, affecting both major commercial publishing houses and smaller or society publishers. All editorial decisions have been communicated to the publishers, who are responsible for communicating outcomes to their editorial boards, authors and readers.
Once we determine that a journal no longer meets our quality criteria, we have a responsibility to act. We will continue to identify journals of concern and de-list any journals which fail to meet our quality criteria.
Our shared responsibility in upholding research integrity
We maintain a freely accessible Master Journal List where searchable information about journal coverage is provided. This is updated on a monthly basis and should be considered the authoritative source for Web of Science coverage.
As we continue to investigate how we can provide greater transparency around what is added and removed from the Web of Science, we invite publishers to proactively engage with us to discuss the challenges and issues they face to offer transparency into their processes.
We all have a collaborative responsibility to uphold the principles of research integrity. We believe that by working together with publishers and other stakeholders, we can ensure that the integrity of the scholarly record is upheld so that research outcomes can benefit everyday life.

domain: literature


text:
What you absolutely need to know about your move into aged care
Aged Care Financial Advice
What you absolutely need to know about your move into aged care
Aged Care Advisor Luke Andrews has more than 12 years’ experience in helping people transition into aged care accommodation. In this article he draws on his deep knowledge to answer seven key questions he is often asked about a move into aged care.
1. Do I have to sell my house before entering permanent residential aged care?
When you sign a residential care agreement you are agreeing to room price and an additional service fee if applicable, all other fees are charges are determined by the Government.
If you do not provide a refundable accommodation deposit you will be asked to pay a daily accommodation payment from day one.
You then have 28 days to inform the facility how you intend to pay for your room, and if you elect to pay a deposit they expect to receive this within 6 months unless otherwise informed by the person or their family.
What this means is that you can get the care you require and still have time to arrange your finances with the help of an aged care financial specialist.
2. What if I don’t pay the RAD within 6 months? Can they kick me out?
Residential aged care is governed by the federal Aged Care Act (1997) and this provides security of tenure to all residents, irrespective of whether they have paid their account or not. This is why most aged care facilities will require that a family member acts as a guarantor to the payment of the fees, or a caveat is raised on the person’s property by the aged care provider.
Under the Act an aged care facility can only ask someone to leave if they can no longer care for them or they are a danger to themselves or others.
Aged care facilities have “ageing in place” meaning they have the ability to care for people until they are palliative. Usually, the point at which they can no longer care for someone arises where there are behavioral issues that require psychogeriatric intervention.
3. I saw on the news that people lost their accommodation deposit at a facility in Melbourne. If the facility goes bankrupt I will lose my refundable accommodation deposit?
The facility in Melbourne where people lost their room deposits was a supported residential service which is not regulated by the federal Aged Care Act (1997).
In facilities regulated by the federal Aged Care Act (1997), the refundable accommodation deposit is federal government guaranteed and repayable to a person or their Estate within 14 days of leaving. Aged care facilities are financially audited by the Government each year and must account for the deposits they hold.
4. What if I don’t like it, can I leave?
A person can leave permanent residential aged care by giving 14 days written notice to the facility and they will be charged care fees for these 14 days, and any refundable accommodation deposit refunded to them.
Furthermore, most facilities provide up to 52 days of social leave per year for holidays or visiting family.
Whilst reassuring that an easy exit exists if required, it is always worth having a conversation with facility management before executing this option as often care needs/expectations are mis-understood on both sides and a resident may have access to more care options within the facility than they realise.
5. Why can’t I use my full respite care allocation prior to becoming a permanent resident to save money?
Respite care is designed to give a person’s carer a break. The Government funds up to 63 days of respite care per financial year per eligible person.
On respite care a person pays just the daily care fee and additional service fee if applicable, and the aged care facility receives either a low-care or high-care respite supplement from the Government to cover the cost of the room and nursing care.
An aged care facility, depending on its size, also has a quota of respite days it can offer, which is why they often cannot allow someone to use their full 63-day allotment at once, particularly if there is an intention or need for permanent care.
From a care perspective, if there is an intention to become a permanent resident, it is often not in a person’s best interests to remain on respite for an extended period. This is because when a person becomes a permanent resident, the aged care facility must prepare a detailed Medicare care plan for the person including any allied health needs such as physio or podiatry, and this can be subsidised by the Government. Therefore, by becoming a permanent resident a person gets access to more individualised care which will benefit their overall health.
6. What if I have too many assets, will I get any support from the Government in residential aged care?
A person’s cost of clinical care is measured on a Medicare scale which reaches a maximum of approximately $260 per day, with most people being over $100 per day in terms of care cost.
A person’s means-tested care fee is their contribution towards their cost of care based upon their level of assets and income (means) and cannot be greater than their cost of care. This means-tested care fee is capped at an annual amount of $29,399.40, or an average of $80.55 per day during one year in care. Therefore, even someone paying their full cost of care daily due to their significant means will receive a subsidy equivalent to the difference between their cost of care as determined by Medicare and $80.55 per day over a full 12 month stay in care.
Furthermore, there is a lifetime cap for means-tested care fee contribution that would see someone who reaches the annual cap ceasing to pay a contribution to their clinical care after approximately 2.5 years in care, at which point their clinical care needs are fully subsidised by the Government which could cost up to $260 per day.
7. Will I pay less in aged care if I transfer assets to my children shortly before I enter?
Upon going into aged care, a person’s means are assessed by Services Australia to see if they are eligible for any subsidy for their room or care costs. Under the rules applied by Services Australia an individual/couple is entitled to gift up to $10,000 per financial year and no more than $30,000 over a rolling five-year period, with any amounts greater than this continuing to be treated as a financial asset by Services Australia and form part of the aged care assets and income assessment.
Furthermore, gifting of assets may deprive people of financial resource that they actually need to cover aged care costs, incur costs upon transfer (i.e. capital gains tax and stamp duty), and in the case of a family home result in an asset which is already favorably treated by Services Australia immediately becoming an assessable asset for both the Age pension and aged care cost determination placing the aged care entrant in a worse position.
There is always a way to be financially viable in residential aged care and getting the right specialised aged care financial advice is the first step towards this. Our team of experts are independent of the government and aged care facilities. They understand your concerns and have significant experience in working with people entering care and their families to provide smarter aged care solutions. To find out more about how we can assist you to find the best aged care outcome, contact your advisor.
This information is general in nature and is provided by Partners Wealth Group. It does not take into account the objectives, financial situation or needs of any particular person. You need to consider your financial situation and needs before making any decisions based on this information.

domain: law


text:
Top 10 guilt-free healthy chocolatey snacks recommended by mums
If you are trying to lose weight but LOOOOVE chocolatey snacks, then you have come to the right place.
Our community of mums have not only been busy whipping up delicious guilt-free chocolate snacks in their kitchens.
Prepare to have your mind blown. Yes, these snacks are all available on our 28 Day Weight Loss Challenge.
10 guilt-free chocolatey snacks loved by mums!
1. Chocolate Microwave Lava Mug Cake
This one needs no introduction. Eleanor Hannah says “Lava Cake you complete me!”
2. Wholemeal chocolate chip muffins
Rachel Delaney says “Umpteenth batch of these delicious muffins made this month. My kids absolutely love them and have no idea they’re healthy!”
3. Healthy Chocolate Coconut Brownies
Natasha Behm says “he he he Heated my Healthy Chocolate Coconut Brownies in the microwave at work and everyone followed the small to my desk drooling!”
4. Chocolate, peanut butter smoothie bowl
Debbie Matthews says “Hello, chocolate peanut butter smoothie bowl. This is not going to last long. I did not add the crushed nuts, but added chia seeds instead. Go Healthy Mummy.”
Recipe available to 28 Day Challenge members.
Want other smoothie recipes? Check out 15 weight loss smoothies to combat sugar cravings.
5. Healthy Tim Tams
Sarah Cryer says “I have no words….. they are delicious Healthy Tim Tams. Yum!”
6. Chocolate Chip Banana Bread
Eleanor Turney says “My daughter is transitioning from nursery to school. Can’t believe my baby is that old already! I’m sad but also really excited for her as she gets ready for this next stage in her life.
I’m feeling the need to comfort eat so I’ve whipped up this beauty. Chocolate Chip Banana Bread. If only it would cool quicker!”
7. Four Ingredient Sugar-Free Rocky Road
Vanessa McAdam says “A little bit of snack prep this morning – and so easy to do and all looks devilishly naughty – but we all know it’s not. 20 snacks done! Another delicious rocky road slice!”
No Sugar Rocky Road x 8 (as requested by hubby).”
8. Chocolate Dipped Strawberries
I wanted to cheer her up so I’ve just made her favourite ‘Choc Dipped Strawberries'”
These are just one of the amazing 28 Day Weight Loss Challenge Snacks! Yep there in there.”
9. Chocolate Weetbix Slice
Kym Williamson says “Always needs some Chocolate Weetbix slice in the fridge and the freezer.”
“Just my favourite snack when I need a chocolate fix after a long night up with the 6-month-old and a tiring day with my super energetic 2.5yr old.”
“Stops me raiding the corner shops’ shelves!”
Sarah Cryer says “Yep, that would be a Weetbix slice”.
10. Chilled Chocolate Orange Pudding
Nikki Lea Eckley syas “Chilled chocolate orange pudding oh yes. Second time this week and I think I’m becoming addicted”.
Recipe available to 28 Day Weight Loss Challenge members.
The Healthy Mummy team would like to thank all the mums who submitted photos of their delicious chocolate creations. Who knew eating healthy could look this yummy?
Want access to these and thousands more mouthwatering snacks? Join the 28 Day Weight Loss Challenge TODAY!
Think of the 28 Day Weight Loss Challenge as the best value personal trainer, dietitian, meal planner, chef and motivational coach with DAILY support – that you have access to every day – without the high cost and all created JUST FOR MUMS.
Each month is DIFFERENT on the 28 Day Weight Loss Challenge. EVERY MONTH you receive NEW 28 Days of FAMILY FRIENDLY customisable meal plans, daily exercise plans with videos and daily support. It’s also breastfeeding-friendly.
The 28 Day Weight Loss Challenge has been able to help thousands of mums lose more than three million kilograms (combined).

domain: food


PLYMOUTH - Two men are facing charges after police allegedly found cocaine and drug paraphernalia in a local home.
Jonathan Hine, 50, of 132 High St., and David Marshall, 31, of Wethersfield, were both arrested Tuesday after police and a probation officer searched Hine’s home - where Marshall has reportedly been staying.
According to the police report, Hine’s probation officer believed he had a firearm in the home and that he has been involved in drug activity. Hine is on probation for a conviction on a charge of possession of a controlled substance. One of his probation conditions prohibits him from having any guns.
During a search of the home at about 11 a.m. Tuesday, police said they found multiple bags of cocaine - weighing a total of 24 grams - a pellet gun, a glass vile labeled testosterone cypionate, a bottle with unknown pills inside, a smoking pipe, a digital scale, two syringes, a number of wax paper baggies and two snorting devices.
Marshall, who police say initially lied about his name, was charged at the scene with criminal impersonation, interfering with police, possession of drugs near a prohibited place, possession of drug paraphernalia and possession of a controlled substance. During his hearing Wednesday in Bristol Superior Court, Judge Richard Dyer said he could not find probable cause for the charge involving possession near a prohibited place, as the alleged place of prohibition - a school, church or another drug-free zone - was not detailed in the police report.
Additionally, Marshall was wanted in connection with a warrant alleging he failed to appear in Waterbury court on charges of third-degree burglary, third-degree criminal mischief and conspiracy to commit sixth-degree larceny.
Marshall is being held on $85,000 bond, and is due back in court on April 6.
Hine was charged with criminal possession of a weapon, sale of illegal drugs, possession of drugs near a prohibited place, possession of a controlled substance and possession of drug paraphernalia near a prohibited place. Dyer on Wednesday had the same dilemma with Hine’s charges as he did with Marshall’s. He did not find probable cause on any offenses that involved a drug-free zone.
“That doesn’t mean they can’t prove this later on,” Dyer said.
Hine is being held on $60,000 bond, and is scheduled to appear in court again on April 25.
Neither man entered any pleas on Wednesday. Although, they both maintained that the white, powdery substance found by police was not cocaine. Court officials said the drugs could potentially be retested if the proper motion is filed.
Justin Muszynski can be reached at 860-973-1809 or at firstname.lastname@example.org.


text:
Vincent Emanuele is a writer, activist and radio host who lives in the United States. He's a member of Veterans for Peace and the National Writers Union. A former US marine and Iraq War veteran, he spoke to Green Left Weekly’s Pip Hinman about the first days of the Trump administration and the mass protests that have broken out.
* * *
How would you describe the political atmosphere in the US after the Trump inauguration?
Well, it depends. If you're a racist or a member of the 1% you're feeling pretty good about things right now. The Alt-Right is emboldened. Neo-Nazi organisations are empowered. The same is true of the police. Trump, unlike most US presidents, is actually delivering on his campaign promises, at least some of them — a point we can return to later. Right now, the Trump administration is implementing a sort of blitzkrieg shock doctrine strategy, but it's also created an amazing response.
As the world knows, the US experienced the largest single day of protests in the history of the country. That's quite an accomplishment. Local organisations are forming in areas where nothing previously existed.
Remember, the Democratic Party is more conservative than your Labor Party and our unions have been decimated. Roughly 11% of the workforce is unionised. In other words, leftwing political institutions are severely lacking. NGOs are not the answer, though some of them do good work.
People are seeking alternatives. That's a daunting task, but it's also a wonderful opportunity to break with the past and develop new institutions, ideas, values, programs, and so forth. Here, I find inspiration. All of that being said, we have to be intentional about creating those alternatives.
In many ways, we've been here before: we've experienced six years of Nixon, eight years of Reagan, eight years of Bush II, and now Trump. In the past, leftwing political movements haven't been able to create an electoral alternative to the Democratic Party and that remains a serious challenge.
Activists are struggling with how they should relate to the Democratic Party. Often, movement energy will be sucked back into the utterly absurd US electoral process, which, as most people know, is far too long and expensive. It's a huge distraction. Some nations elect prime ministers in less than five weeks. So, how do we break that cycle? That remains a serious question. How do we create serious alternatives? We can't allow bloated NGOs, establishment Democrats and other faux-progressive groups to hijack what is currently a very organic, multicultural, and in some ways, quite militant movement.
Does the scale of the anti-Trump protests have any precedent in the history of US presidential inaugurations?
The protests immediately following Trump's inauguration have no precedent: they were the largest rallies we've ever seen on a single day in the US. The following two weeks have also been unprecedented. The breadth of the protests, civil disobedience and direct actions has been breathtaking.
On a personal note, I'm hearing from friends and family members who have never been involved with political movements. Now, they want to get involved. It's the only silver lining I can see from Trump's victory: increased participation.
I told my friend the other day that I feel like we've fast-forwarded to 2007, when Bush was very unpopular and quickly losing any level of credibility and respect, not only within the US but also abroad. The energy is very contagious.
But again, we've been here before: we know how to protest. And we're getting better and better at it. But the Egyptians also knew how to protest. They were able to dispose of a dictator by occupying public spaces. But that didn't equate to serious political reforms or a restructuring of power.
Immediately, we have to focus our energy on discrediting Trump. That strategy is working. But we can't make the entire movement about being anti-Trump. I see parallels, once again, with the Bush era. I remember going to protests and people viscerally denouncing Bush and Cheney. However, by focusing on Bush and Cheney and individuals, the movements created during that period were unable to create alternatives — electoral or otherwise.
Sure, we elected the nation's first black president, and that's quite an accomplishment in a nation built on slavery and institutional racism, but let's always remember that Obama's centrism was a major factor in Trump's rise to power.
The more we can focus our critiques on the institutions of power and not those who temporarily occupy those institutions, the more successful we'll be in the long-term. The short-term goals, at least from what I can tell from conversations and observations, is to make the country ungovernable.
Now, what does that exactly mean? We'll see. It's wintertime in the US, so once it warms up, say in a couple of months, I expect major direct actions and civil disobedience, possibly on a scale previously unwitnessed in the history of the US. I think you'll see small-scale and even large-scale strikes. I can imagine activists occupying public spaces, corporate offices, public lands, extraction sites, airports and the like.
How divided is the US establishment over the Trump presidency?
Well, not to sound too cynical, but the Democrats are behaving exactly how most of my leftwing friends expected them to behave: they're approving Trump's nominees for his cabinet, which is filled with alt-right media personalities, Southern racists, CEOs and military generals. The corporate coup d'état is happening in real-time, and it's quite scary.
Republicans, as always, are acting virtually in lock-step with the Trump administration. The media is painting a picture of a divided Republican party, but most of that is superficial.
Only two Republicans voted "no" and only on one of Trump's nominees, Betsy DeVos, the sister of Blackwater founder and CEO, Erik Prince. Both Prince and DeVos are ultra-Christian and hold some of the most regressive views imaginable. They are truly dangerous people. DeVos will be running the Department of Education. Her brother, Erik, is currently advising Trump's national security team.
Rex Tillerson, the former CEO of ExxonMobil, was recently confirmed as Trump's Secretary of State. Here's a corporation, Exxon, that's being sued because they knew their industry was creating climate change since 1987, yet intentionally misled the public about the issue for 30 years.
Our representative to the United Nations, Nikki Haley, essentially threatened the rest of the world during her first official press conference, vowing to "take names" of those who reject US hegemony. Trump's Secretary of Defence, General James Mattis, is a war criminal, and the list goes on. This is, without question, the most reactionary administration that's ever been assembled in the modern era.
To the extent that divisions do exist within the establishment, activists should exploit those schisms and use them to our advantage. We have to leverage power. Sometimes, we'll directly confront power. Other times, we have to be very sophisticated about how we interact with and attack concentrated power.
If we can push some Republicans to distance themselves from Trump, great. If we can push Democrats to the left on certain issues, that's fine as well. But I don't think activists should focus too much on what the establishment is doing or not doing. We have to be smart, but we also don't want to fall into the media's game of constantly focusing on what those in power are debating, as opposed to what the people in the streets are debating.
Is there any potential for the mass movement that seemed to develop around Bernie Sanders’ nomination bid to come back in a more powerful and politically independent way?
The movement surrounding Bernie was very inspirational and politically significant, but it was also frustrating and inadequate.
So, on the positive side, millions of people, particularly younger folks, were exposed to an alternative to Neoliberalism, Neoconservatism and the alt-right. That's invaluable. The concepts of democratic socialism were discussed publicly for the first time in my life. People who had never been to a political event in their lives were engaged and mobilised.
Millions of people learned very basic organising skills: how to write a press release; how to make phone calls; how to hold fundraisers; how to knock on doors; and a whole host of other valuable skills and lessons.
Bernie also did really among rural whites, which is something activists should build upon. Right now, there's a lot happening in urban areas, but mobilising progressive whites in the rural parts of the US is essential in my thinking.
There are cultural differences and geographical challenges, but it must be done. Obviously, the [First Nations-led] resistance at Standing Rock [in North Dakota against the Dakota Access Pipeline] has been extremely encouraging. Building on that momentum is also key to moving forward. New alliances are forming — veterans, indigenous communities, environmentalists. Standing Rock, however, is a far cry from Detroit or Chicago.
How can we bridge those gaps? How can we bring black and brown communities together? How can we connect suburban and rural whites, many of whom, at least the younger folks, voted for Bernie, to groups like Black Lives Matter or the Latino communities fighting back? Those are the sort of questions activists are exploring.
I'm currently working on an article titled, "Beyond Bernie." The point of the article is that Bernie helped take progressive politics to the mainstream. Leftwing ideas were discussed in the mainstream. Again, this was great.
But the limitations to Bernie's campaign were not only racial: his foreign policy was pretty bad, actually. He made what are now utterly uncontroversial statements about regime change and the war in Iraq. But remember, Trump also spoke out against the war during the campaign. My point is that only one half of the story was told during Bernie's campaign: the domestic side.
And you can't really tell even that side of the story without also mentioning the other side: US Empire. Something like 54 cents of every discretionary dollar is spent on the US Empire. The state has been completely hijacked by the military industrial complex. Much of the state's resources, time, energy and talent are invested in killing people, which is why the US is really good at killing people.
Our infrastructure is deteriorating, our public schools are being dismantled and basic social welfare programs are being defunded, but we always have money for another war, or another drone, or another tank.
The elephant in the room is still the US Empire. And unfortunately Bernie didn't touch that issue, nor did he create an independent political party or even an independent political infrastructure.
Those are his two main downfalls. But now it's up to activists to build on the successes and failures of Bernie's campaign. The people I'm running into at these events are much more sophisticated and aware of these issues than I was at their age. That gives me hope.
What are the dangers of the Trump administration escalating US military interventions or starting new ones?
Here, I think it's best to prepare for the worst. Steve Bannon, Trump's main adviser who now sits on the National Security Council is the former CEO of the alt-right media platform, Breitbart. He's a known racist, but even more importantly, he's a proponent of this idea of a “clash of civilizations” between the West and Islam.
After fifteen years of the miserable and criminal War on Terror, and after decades of CIA overthrows and US militarism, Bannon wants to escalate the situation.
Some people were fooled into believing that Trump was an isolationist, but that's simply untrue. He's an authoritarian-jingoist who now controls the most powerful military empire in the history of mankind.
Trump now has 1,000 military bases, the world's largest nuclear arsenal, the world's largest navy and the world's most sophisticated weapons systems at his command. I think the dangers posed by this administration cannot be overstated. Like climate change, it would be better for us to hope for the best and prepare for the worst.
In the meantime, we need an anti-imperialist movement to emerge and that hasn't happened, nor does it look like it's on the horizon. A lot of organising is taking place, but as I mentioned above, the elephant in the room is still US Empire. And in order to address US Empire, we must address US nationalism.
And unfortunately, even many progressives have a difficult time dealing with those issues. I think that's changing, but we'll see. That's up to us.


text:
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Chisel Tip Acrylic Paint Marker - Silver
Introducing the Silver Chisel Tip Acrylic Paint Marker
If you're in the market for a high-quality acrylic paint marker, look no further than the Silver Chisel Tip Acrylic Paint Marker. This versatile and durable marker is perfect for a wide range of artistic and crafting projects. Whether you're a professional artist or a hobbyist, this marker is sure to meet your needs. The silver color adds a touch of elegance to any project, and the chisel tip allows for both broad strokes and fine lines, making it incredibly versatile. With its quick-drying and water-resistant formula, your creations will stand the test of time. Plus, the marker's ergonomic design ensures a comfortable grip, even during extended use.
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The Silver Chisel Tip Acrylic Paint Marker is perfect for a wide range of use cases. Whether you're working on canvas, paper, wood, metal, or plastic, this marker is up to the task. It's ideal for creating intricate designs, adding accents to larger pieces, or even touching up existing artwork. The silver color is versatile and can be used in a variety of artistic styles, from traditional to contemporary.
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When using the Silver Chisel Tip Acrylic Paint Marker, it's important to shake the marker well before each use to ensure the paint is properly mixed. Additionally, store the marker horizontally to maintain the integrity of the tip and prevent the paint from settling. For best results, test the marker on a small, inconspicuous area before using it on your final project to ensure the color and flow meet your expectations. Finally, be sure to cap the marker tightly after each use to prevent the paint from drying out.
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Please view this informative powerpoint presentation, which contains ODU standards and wear. A special thanks to CAPT Bruce Tierney for creating the presentation on behalf of the ACOA.
Tracy Tilghman, MPH
LT, U.S. Public Health Service
Chair, Junior Officer Advisory Group (JOAG)
The August 9, 2013 JOAG General Meeting Minutes are posted.
New Get Fit-Stay Fit article posted for Septmeber 2013!
Please join us this Friday, 9 November 2012 at 1300 EST. We are honored to have Dr. Mary Beth Bigley speaking on the timely and important professional development topic, "JOAG and the National Prevention Strategy". Slides for the presentation are forthcoming. If you have any questions for the speaker please email them to email@example.com by COB Wednesday, 7 November 2012.
Call in: 1-213-342-3000 (Note: this is a toll line and long distance charges apply)
Participant Access Code: 6904646
Notes about the conference line:
* Because of the number of people calling in, it may take more than one attempt to connect to the conference line. (You may hear a message that "All circuits are busy.") Please keep trying to connect, and consider dialing in several minutes before the call begins.
* Once connected, you may be instructed to announce yourself to the call. Please do not announce yourself, as it interrupts the call. Thanks!
* Please put your phone on mute when not speaking. If your phone does not have a mute button, press *6 (star 6).
About the Journeyman Speaker Series: The Journeyman Speaker Series is developed by the JOAG Professional Development Committee to bring relevant information to Junior Officers about Corps-related issues. For more information on Journeyman Speaker Series, visit the JOAG Website: http://www.usphs.gov/corpslinks/JOAG/meetings_journeyman.aspx
Scott Steffen, Ph.D.
LCDR, U.S. Public Health Service
Executive Secretary, Junior Officer Advisory Group (JOAG)
The First Lady of the United States of America, Michelle Obama, has challenged Americans to promote physical fitness and good nutrition habits in our youth. As officers in the U.S. Public Health Service, it is important that we serve as leaders in our communities to respond to this challenge. The OHWPS would like to announce a very exciting opportunity for JOAG officers across the country to participate in the national Let’s Move! campaign. On behalf of JOAG, the OHWPS has created a Let’s Move! volunteer program, which offers JOAG members the chance to lead projects that promote the ideals of Let’s Move! in their very own hometowns.


What's new in this version (1.2.1):
Added Debit Days = !
A fire shift calendar for Houston, TX. It shows A, B, C, and D shifts in a colored order.
To sync with Google calendar just put "payday" or "Trade off", etc. somewhere in the title of the event. The corresponding symbol will show up in Fire Shifts.
$ = Payday
TO = Trade Off
TW = Trade Work
V = Vacation
* = Holiday
! = Debit Day
Apps from the same developer
Fire Shifts - Seattle
A fire shift calendar for Seattle area fire fighters. A, B, C, and D shifts are color coordinated ...
Fire Shifts - Free
A free customizable Fire and EMS Shift Calendar.
Easily select various shift types such as 24/48 (ABC ...
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Get more out of your Nexus One with THE guide to hidden features, Tips & Tricks
Androlicious.com is a website that shows applications and games from Android Market. You can download and install apps and games directly from Android Market using an Android phone or by using WebConnect mobile application.


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GUAVA - STARLINGS WHITE
A firm guava with crisp, clean white flesh that if not cross pollinated will produce fruit with less seeds that can be eaten fresh out of hand like an apple. Cross pollinated fruit will produce extremely small central cavities dotted sparsely with seeds. Fruits are large and heart shaped, green skinned and highly aromatic. Superior flavour to that of Thai varieties. A must have for those who tend to avoid guavas owing to high seed content.
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Can be pruned to 2m
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Tree Information on growing, planting, pruning, maintenance, ripening, taste, pick or bonsai tips. But mainly how to grow a Guava - Starlings White Share Your Review & Advice or ask questions on our Forum
Create Your Own My Edible Backyard Page and your feedback will appear here.


Museum of Failures of Innovations
I stood along my dad looking at Apple’s Newton, a previous avatar of today’s smartphones that was launched in 1993. We were at the Museum of Failures of innovation that opened in the city of Helsingborg in Sweden last month.
“I remember when it came out. I wanted one,” my father said. “It disappeared from the market before I could lay my hands on it.”
So, the Apple mania was commonplace before us millennials as well. I had never seen a Newton before, and had only heard stories of it. It was ahead of its time, my father reminiscized. Though larger than my fist, and accompanied with a stylus, the device didn’t appear user-friendly but was certainly packed with features of a powerful computer of that time.
The museum was full of such spectacular flops, some ill-timed flunks and some absolute no-hopers (Heinz’s green ketchup anyone?).
“The idea behind this concept is to celebrate failures, and to learn from them,” said Dr. Samuel West, the brainchild behind the museum. He had walked over to us to show a finger glove to browse the smartphone and protect the screen from finger prints. Who could have thought that we needed such an innovation?
Helsingborg is Sweden’s eighth largest city with a population of only 130,000. In terms of attractions, it has little to boast about outside an elementary beach, and the Swedish royal family's country mansion, Sofiero. However, since the opening of the museum, the city has seen a surge of tourists queuing up to visit souvenirs of corporate failures.
The museum is nestled on a by-lane close to the city center (it will soon shift to a bigger location within Helsingborg to accommodate an ever-increasing collection), and currently displays close to 100 installations. This museum is one of its kinds, and makes an interesting stop-over for studying tangible remainders of failed launch stories rarely spilled beyond business books.
Ten notable failures on display at the museum
Crystal was a clear cola drink made by PepsiCo to match to the theme of purity, which was a fad in the early nineties. The product saw positive response in initial testing and launch, and PepsiCo poured in millions on its marketing campaign. Not to be left behind, Coca Cola launched a similar clear soft drink Tab Clear in the same year. However, both the brands died fairly quickly for consumers didn’t like the taste, and were taken off the market once the novelty faded. There was no Crystal Pepsi launch in India, so I had never heard about it. I was lucky, for Dr. West had scored a bottle and he let me have a sip from it. It didn’t taste bad.
Coca Cola Blak
By: The Coca Cola Company
Did you know that Coca Cola once launched a coffee drink? The idea may not seem too outlandish, for all cola drinks have caffeine, and since Coca Cola was in beverages business, it would have been natural to consider a brand extension into the world’s favourite drink. The drink was aimed at sophisticated drinkers, male, above 30 years. Though the taste didn’t resonate with most drinkers, and Coca Cola took the brand off the market, it was interesting to see the company launch coffee machines under the same brand name again in 2010.
Frozen Beef Lasagne
Some innovations by certain corporations are simply mind boggling. For instance, the oral hygiene company Colgate once launched a frozen dinner, a beef lasagne! They must have quickly recognised that they have done something embarrassing, for they took away the product from the market quickly, and have ever since denied that any such product ever existed. Thanks to the museum, which reconstructed the original packaging, we can now see how it looked.
The ballpoint pen company, Bic, once launched a pen specifically for women. It had floral patterns and glitter on the plastic body and, well, the rest was the same. The company claimed that it fitted comfortably in a woman’s hand. The product was a complete bust and was ridiculed the moment it was launched. Some innovations succeed because entrepreneurs aim to solve a real problem that at times they are struggling with themselves. But when corporations run out of ideas, such futile innovations are born.
In India, the weapons manufacturer, Bofors, has a notorious name given the association with bribery scandals. Much before the scandal happened, Bofors tried to make itself a household name by launching ‘peace products’, essentially goods for common household use, such as toothpaste. However, rumours that these toothpastes had toxic materials killed the peaceful product, and Bofors went back to making guns.
P&G once tried to tackle the challenge of eating fried food by inventing a molecule, Olestra. It was a fat substituent, and P&G thought it had found way to the Holy Grail of food business. But for unwelcome side effects that came with Olestra, which was not absorbed by the human body. P&G quickly withdrew the product and was left standing with a wasted investment in a brand new multi-million dollar manufacturing plant. Later, P&G found another application for Olestra in environmental remediation, and managed to salvage some of its investment in research and infrastructure.
No More Woof
By: No More Woof
A headphone-like-contraption for pets that, when worn, could communicate their thoughts such as ‘I am hungry’, ‘Leave me alone’, and so forth. Unbelievable, correct? Apparently, a lot of people didn’t think so and invested money in this Nordic start-up that provided convincing prototypes and demos. The company claimed ‘using advanced brainwave measurement equipment together with new software’ to identify 14 separate thoughts. However, no real commercial product ever came out from this start-up. The website www.nomorewoof.com still exists but has a disclaimer claiming that the product is still a work in progress.
By: Peek Inc.
At the time when frenzy around Twitter was peaking, an American company launched a dedicated device to let users access to their Twitter stream on the move. The 200 US dollars device could serve no other purpose than read or write tweets. Yes, true. And the device let out a chirp when a new tweet arrived. But was it really needed, or was it another case of corporate lethargy where imaginary problems were attacked? The market gave the answer and the product didn’t survive more than a year. On its launch, Gizmodo ran a story titled, ‘The TwitterPeek Is So Dumb It Makes My Brain Hurt’.
Trump, The Game
By: Milton Bradley Company and Parker Brothers
1989-90; re-launch in 2004
Endorsed by Donald Trump himself, this game was expected to be a big hit and sell close to two million units. In its first launch, it managed to scrap through some 800,000 units. Not bad, one would say. Trump got 60% of the revenues from these sales. However, the complexity and boring nature of the Monopoly inspired game didn’t make it popular. Sample this: it came with a ten page instructions! A casino owner even invited Trump to play the game on a million-dollar wager, but Trump turned down the offer. A simplified version of the game was released in 2004, to ride on the success of Trump’s show ‘The Apprentice’, but the fate of the game remained the same as in the ’89 launch.
Many of us perhaps remember this music player which was Microsoft’s tepid attempt at counteracting Apple’s iPod success. The expectations were high from this product, but it offered nothing new and disappointed even the most loyal consumers of Microsoft. The sales never really picked up but Microsoft kept the brand afloat for six years. Sense prevailed and the hardware was discontinued in 2011, followed by termination of all Zune services in 2012. To give credit to Microsoft, it managed to comeback to compete against Apple in hardware business again with its Surface line of products. Possibly, failure of Zune helped them learn and prepare for the future.
A version of this story appeared in National Geographic Traveller India


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|Call||Career Development Fellowship (CDF)|
Predictors of local emergence and spread of Artemisinin resistance among Ugandan Plasmodium falciparum parasites (Pfkelch13 emergence)
Makerere University, College of Health Sciences
|Type||Name||Title||University||Start Date||End Date|
|PhD||Hindum Lanyero||Assistant lecturer||Makerere University, College of Health Science||2018||2022|
|PhD||Kimbowa Isaac||Assistant lecturer||Makerere University, College of Health Science||2018||2022|
|Makerere University, Uganda||Bachelor of Science||2003-08-23|
|Makerere University, Uganda||Master of Science in Pharmacology||2011-02-12|
|Makerere University, Uganda||Philosophy||2017-02-12|
Though antimicrobial stewardship (AMS) programmes are the cornerstone of Uganda’s national action plan (NAP) on antimicrobial resistance, there is limited evidence on AMS attitude and practices among healthcare providers in health facilities in Uganda. We determined healthcare providers’ AMS attitudes, practices, and associated factors in selected health facilities in Uganda. We conducted a cross-sectional study among nurses, clinical officers, pharmacy technicians, medical officers, pharmacists, and medical specialists in 32 selected health facilities in Uganda. Data were collected once from each healthcare provider in the period from October 2019 to February 2020. Data were collected using an interview-administered questionnaire. AMS attitude and practice were analysed using descriptive statistics, where scores of AMS attitude and practices for healthcare providers were classified into high, fair, and low using a modified Blooms categorisation. Associations of AMS attitude and practice scores were determined using ordinal logistic regression. This study reported estimates of AMS attitude and practices, and odds ratios with 95% confidence intervals were reported. We adjusted for clustering at the health facility level using clustered robust standard errors. A total of 582 healthcare providers in 32 healthcare facilities were recruited into the study. More than half of the respondents (58%,340/582) had a high AMS attitude. Being a female (aOR: 0.66, 95% CI: 0.47–0.92,
To identify, categorize, and develop an aggregated synthesis of evidence using the theoretical domains framework (TDF) on barriers and facilitators that influence implementation of clinical imaging guidelines (CIGs) by healthcare professionals (HCPs) in diagnostic imaging
The protocol will be guided by the Joanna Briggs Institute Reviewers’ Manual 2014. Methodology for JBI Mixed Methods Systematic Reviews and will adhere to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines (PRISMA-P). Information source will include databases (MEDLINE, EMBASE and The Cochrane Library), internet search (https://www.google.com/scholar), experts’ opinion, professional societies/organizations websites and government bodies strategies/recommendations, and reference lists of included studies. Articles of any study design published in English from 1990 to date, having investigated factors operating as barriers and/or facilitators to the implementation CIGs by HCPs will be eligible. Selecting, appraising, and extracting data from the included studies will be independently performed by at least two reviewers using validated tools and Rayyan – Systematic Review web application. Disagreements will be resolved by consensus and a third reviewer as a tie breaker. The aggregated studies will be synthesized using thematic analysis guided by TDF. Results: Identified barriers will be defined a priori and mapped into 7 TDF domains including knowledge, awareness, effectiveness, time, litigationand financial incentives
The results will provide an insight into a theory-based approach to predict behavior-related determinants for implementing CIGs and develop strategies/interventions to target the elicited behaviors. Recommendations will be made if the level of evidence is sufficient
Resource-constrained settings that are in the process of adopting CIGs may opt for this strategy to predict in advance likely impediments to achieving the goal of CIG implementation and develop tailored interventions during the planning phase. Systematic review Registration: PROSPERO ID = CRD42020136372 (https://www.crd.york.ac.uk/PROSPERO).
Background: In the absence of an effective vaccine, malaria treatment and eradication is still a challenge in most
endemic areas globally. This is especially the case with the current reported emergence of resistance to artemisinin
agents in Southeast Asia. This study therefore explored the prevalence of K13-propeller gene polymorphisms among
Plasmodium falciparum parasites in northern Uganda.
Methods: Adult patients (≥18 years) presenting to out-patients department of Lira and Gulu regional referral hospitals
in northern Uganda were randomly recruited. Laboratory investigation for presence of plasmodium infection among
patients was done using Plasmodium falciparum exclusive rapid diagnostic test, histidine rich protein-2 (HRP2) (Pf).
Finger prick capillary blood from patients with a positive malaria test was spotted on a filter paper Whatman no. 903.
The parasite DNA was extracted using chelex resin method and sequenced for mutations in K13-propeller gene using
Sanger sequencing. PCR DNA sequence products were analyzed using in DNAsp 5.10.01software, data was further
processed in Excel spreadsheet 2007.
Results: A total of 60 parasite DNA samples were sequenced. Polymorphisms in the K13-propeller gene were detected
in four (4) of the 60 parasite DNA samples sequenced. A non-synonymous polymorphism at codon 533 previously
detected in Cambodia was found in the parasite DNA samples analyzed. Polymorphisms at codon 522 (non-synonymous)
and codon 509 (synonymous) were also found in the samples analyzed. The study found evidence of positive selection in
the Plasmodium falciparum population in northern Uganda (Tajima’s D=−1.83205; Fu and Li’s D=−1.82458).
Conclusions: Polymorphism in the K13-propeller gene previously reported in Cambodia has been found in the Ugandan
Plasmodium falciparum parasites. There is need for continuous surveillance for artemisinin resistance gene markers in
Background Substandard anti-malarial agents pose a significant challenge to effective malaria control and elimina- tion efforts especially in sub-Saharan Africa. The quality of anti-malarials in most low-and-middle income countries (LMICs) is affected by several factors including inadequate regulation and limited resources. In this study, the phar- macopeial quality of artemether–lumefantrine (AL) in low and high malaria transmission settings in Uganda was assessed.
Methods This was a cross-sectional study conducted among randomly selected private drug outlets. The AL anti- malarials available in drug outlets were purchased using overt method. The samples were screened for quality using visual inspection, weight uniformity, content assay and dissolution tests. The assay test was done using liquid chro- matography–mass spectrometry (LC–MS). The samples were considered substandard if the active pharmaceutical ingredient (API) content was outside 90–110% range of the label claim. Dissolution test was conducted following United States Pharmacopoeia (USP) method. Data was analysed using descriptive statistics and presented as means with standard deviations, frequencies, and proportions. Correlation between medicine quality and independent vari- ables was determined using Fisher’s exact test of independence at 95% level of significance.
Results A total of 74 AL anti-malarial samples were purchased from high (49/74; 66.2%) and low (25/74; 33.8%) malaria transmission settings. The most common batch of AL was LONART, 32.4% (24/74), with 33.8% (25/74) being ‘Green leaf’. Overall prevalence of substandard quality artemether–lumefantrine was 18.9% (14/74; 95% CI: 11.4–29.7). Substandard quality AL was significantly associated with setting (p = 0.002). A total of 10 samples (13.5%) failed artemether content assay test while, 4 samples (5.4%, 4/74) failed the lumefantrine assay test. One sample from a high malaria transmission setting failed both artemether and lumefantrine assay content test. Of the samples that failed artemether assay test, 90% had low (< 90%) artemether content. All the samples passed visual inspection and dissolu- tion tests.
Conclusion Artemether–lumefantrine agents, the recommended first-line treatment for uncomplicated malaria with APIs outside the recommended pharmacopeial content assay limit is common especially in high malaria transmission settings. There is need for continuous surveillance and monitoring of the quality of artemisinin-based anti-malarials across the country by the drug regulatory agency.
Hepatitis B vaccine has contributed to the reduction in hepatitis B virus infections and chronic disease globally. Screening to establish extent of vaccine induced immune response and provision of booster dose are limited in most low-and-middle income countries (LMICs). Our study investigated the extent of protective immune response and breakthrough hepatitis B virus infections among adult vaccinated healthcare workers in selected health facilities in northern Uganda. A cross-sectional study was conducted among 300 randomly selected adult hepatitis B vaccinated healthcare workers in Lira and Gulu regional referral hospitals in northern Uganda. Blood samples were collected and qualitative analysis of Hepatitis B surface antigen (HBsAg), Hepatitis B surface antigen antibody (HBsAb), Hepatitis B envelop antigen (HBeAg), Hepatitis B envelop antibody (HBeAb) and Hepatitis B core antibody (HBcAb) conducted using ELISA method. Quantitative assessment of anti-hepatitis B antibody (anti-HBs) levels was done using COBAS immunoassay analyzer. Multiple logistic regression was done to establish factors associated with protective anti-HBs levels (≥ 10mIU/mL) among adult vaccinate healthcare workers at 95% level of significance. A high proportion, 81.3% (244/300) of the study participants completed all three hepatitis B vaccine dose schedules. Two (0.7%, 2/300) of the study participants had active hepatitis B virus infection. Of the 300 study participants, 2.3% (7/300) had positive HBsAg; 88.7% (266/300) had detectable HBsAb; 2.3% (7/300) had positive HBeAg; 4% (12/300) had positive HBeAb and 17.7% (53/300) had positive HBcAb. Majority, 83% (249/300) had a protective hepatitis B antibody levels (≥10mIU/mL). Hepatitis B vaccine provides protective immunity against hepatitis B virus infection regardless of whether one gets a booster dose or not. Protective immune response persisted for over ten years following hepatitis B vaccination among the healthcare workers.

domain: medical


LONDON – The revelation last year that journalists at the News of the World, a Sunday paper, owned by News Corp., had been involved extensively in hacking into the mobile phones and the voice mail of celebrities led to the closure of this populist paper. Since such hacking is illegal in Britain, News Corp. has been forced to pay large sums in compensation to famous people whose phones were hacked.
Rupert Murdoch, chairman of News Corp. (incorporated in the United States) and his son, James Murdoch, chairman of Sky TV in Britain, were summoned by a parliamentary committee to account for the company’s handling of the scandal. They apologized, but the scandal has continued to reverberate.
David Cameron, the British prime minister was embarrassed. Andy Coulson, a former editor of the News of the World, had been appointed as his press secretary. Coulson had to resign this position and was one of the News International executives arrested for their role in these illegal activities.
To defuse a popular clamor for curbs on the media, the government set up a judicial inquiry headed by a senior judge to investigate the issues and make recommendations on remedial action.
Lord Justice Leveson, on the recommendation of the head of the judiciary, was appointed to lead the inquiry. With the assistance of senior lawyers, Leveson has been hearing evidence from celebrities whose phones have been hacked as well as from editors and senior figures in the media.
Evidence given to the inquiry has showed that journalists from other populist newspapers as well as some more serious journals condoned illegal methods in seeking exclusive stories.
Many celebrities complained vociferously about the media’s invasion of their private lives. While most editors were contrite about illegal activities by their employees, they put up a strong defense of Britain’s free press and were unanimous in rejecting moves to introduce statutory controls, which might be used to limit investigative journalism and the exposure of political and administrative blunders and corruption.
Britain, while it has stringent rules to protect private data such as bank accounts and health records, does not have the sort of privacy rules that in France, for instance, prevent the media from delving into the private life of politicians. Britain does, however, have libel laws, which, in the view of some in the media, limit what can safely be reported. As the costs of bringing a libel action are high, only wealthy people can afford to institute cases; this leads to inequitable outcomes.
Editors and journalists, in giving evidence to the inquiry, have pointed out that newspapers, broadcasting and TV are not the only way in which the public receive news. The role of the Internet has grown exponentially. Many people get their news on iPhones. Twitter, Facebook and other social networking sites provide almost instantaneous information about events and personalities.
The editors argued that it would be unfair to apply rules to the established media while ignoring these unofficial channels. But it is far from clear how such social networking sites can be controlled without destroying Internet freedoms.
The Leveson inquiry is about to turn its attention to relations between the media and the police. The police had been dilatory in their investigations of phone hacking. It was suggested that an understanding had been reached between representatives of News Corp. and the police that inquiries would be limited to the egregious case of a journalist and a private investigator who had hacked into the private phones of Princes William and Harry.
When it became clear that phone hacking was much more widespread than this single case implied, the police were forced to extend their investigation and officers responsible for what seemed to many observers a coverup had to resign.
Fortuitously or not, just before the inquiry could begin to probe the complex relations between News International and the police, a number of senior journalists at the Sun, a populist daily also belonging to News Corp., were arrested together with two officials from the Ministry of Defense and a police officer on suspicion of corrupt practices. It seems probable that police officers were paid (or perhaps provided with other sweeteners) by some journalists to reveal details of current investigations.
Cozy relations between News Corp. executives and those in authority clearly existed at the political level. Members of the Blair and Brown Labour governments were keen to keep their connections with Rupert Murdoch in the hope that, by so doing, his papers would report favorably on government policies. This situation did not change materially when the coalition government was set up in 2010.
David Cameron cultivated the Murdoch press. The Liberal Democrats were, however, left out in the cold and the Murdoch papers, including The Times, have taken every opportunity to snipe at them.
Rupert Murdoch, formerly an Australian and now a U.S. citizen, is a Euro-skeptic. His papers generally play the same tune.
Lord Justice Leveson, so far, has not indicated his likely recommendations, although he has made it clear that the existing toothless press-complaints commission needs replacement by a more effective body. He has shown that he values a free press able to expose scandals.
The Leveson inquiry and its recommendations are important not only for Britain; other democratic societies can learn from our problems and how we decide to tackle them.
Japan, in particular, needs to think carefully about the often too-cozy relationships between journalists and government departments through the kisha club system. To outsiders there often seems to be an understanding in Japan that any attempt to expose failures in Japan’s system of government reflects badly on Japan and should be cloaked over. The Fukushima disaster may have worked to curb this dangerous tendency.
Hugh Cortazzi served as Britain’s ambassador to Japan from 1980-1984.
In a time of both misinformation and too much information, quality journalism is more crucial than ever.
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text:
The Management Board of Euro-Tax.pl S.A. provides the attached consolidated quarterly report for the third quarter of 2017. Br> Br> Br> Br> Legal basis: §5 para. 1 point 1 of Appendix No. 3 to the Regulations of the Alternative Trading System Br> Br> More at: http://biznes.pap.pl/pl/reports/ebi/all,0,0,0,1 Br>
Source: company website, investor relations, current and periodic reports.


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Here’s a super easy recipe for a Christmas favourite! Whether you’ve got friends or family coming round or just fancy bringing some yuletide spirit into your home this winter, these moreish snacks will fit the bill.
- 1x pack ready to roll puff pastry
- 2x handfuls of fresh Parmesan cheese, grated
- Plain flour
Heat your oven to 200°C/400°F/Gas mark 6 and line a baking tray with greaseproof paper
- Place the pastry on a surface lightly dusted with plain flour. Gently roll out to around the size of an A4 piece of paper.
- Sprinkle your first handful of Parmesan over the pastry and fold the pastry in half on the long side so you have approximately an A5 size block of pastry
- Roll out the pastry to A4 size once again (you my need another dusting of flour)
- Using a sharp knife, cut the pastry into strips 1cm wide. Place the strips on your baking sheet – you can twist the strips once or twice if you prefer this look.
- Scatter your cheese straws with one final handful of Parmesan and place in the oven for 12-15 minutes. When the straws are golden brown, remove from the oven and allow to cool before serving.


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dd permanent spot-plants in your garden of this great variety, evergreen and full of winter flower.
If you're looking for a shrub to give your garden long-lasting beauty Viburnum tinus Lisarose is perfect, offering something interesting to see or smell for 365 days of the year. Plant in full sun, half shade or full shade and this lovely shrub thrives.
With beautiful little white starry flowers on bunches callled umbels that appear from around Christmas time every year and last until mid to late spring.
Your Viburnum tinus Lisarose comes in a 3 litre pot – perfect to plant in soil at any time of the year.
These plants arrive in a pot within a box to keep the plant sturdy and upright. The soil area may be covered in sacking or polythene to keep the soil moist which is ideal for the roots.
On arrival lift the plant gently out of the pot to check there are lots of roots showing on the sides of the soil.
Can’t plant straight away?
If you can't plant up your plant straight away, remove the sacking or polythene, and keep your potted plant in a sunny position. Keep the soil moist by watering each day. Look to planting into its permanent position within 5-7 days.
|J Jan||F Feb||M Mar||A Apr||M May||J June||J Jul||A Aug||S Sep||O Oct||N Nov||D Dec|

domain: agronomy


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The close relationship between circadian rhythm disruption and poor metabolic status is becoming increasingly evident, but role of adipokines is poorly understood. Here we investigated adipocyte function and the metabolic status of mice with a global loss of the core clock gene Bmal1 fed either a normal or a high fat diet (22% by weight). Bmal1 null mice aged 2 months were killed across 24 hours and plasma adiponectin and leptin, and adipose tissue expression of Adipoq, Lep, Retn and Nampt mRNA measured. Glucose, insulin and pyruvate tolerance tests were conducted and the expression of liver glycolytic and gluconeogenic enzyme mRNA determined. Bmal1 null mice displayed a pattern of increased plasma adiponectin and plasma leptin concentrations on both control and high fat diets. Bmal1 null male and female mice displayed increased adiposity (1.8 fold and 2.3 fold respectively) on the normal diet, but the high fat diet did not exaggerate these differences. Despite normal glucose and insulin tolerance, Bmal1 null mice had increased production of glucose from pyruvate, implying increased liver gluconeogenesis. The Bmal1 null mice had arrhythmic clock gene expression in epigonadal fat and liver, and loss of rhythmic transcription of a range of metabolic genes. Furthermore, the expression of epigonadal fat Adipoq, Retn, Nampt, AdipoR1 and AdipoR2 and liver Pfkfb3 mRNA were down-regulated. These results show for the first time that global loss of Bmal1, and the consequent arrhythmicity, results in compensatory changes in adipokines involved in the cellular control of glucose metabolism. © 2013 Kennaway et al.
Kennaway, D. J., Varcoe, T. J., Voultsios, A., & Boden, M. J. (2013). Global Loss of Bmal1 Expression Alters Adipose Tissue Hormones, Gene Expression and Glucose Metabolism. PLoS ONE, 8(6). https://doi.org/10.1371/journal.pone.0065255