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Writing a literature review can turn into a real challenge. First of all, you have to find the relevant data from reputable sources. It can be a very time-consuming task because of the lack of the available information. Then, you need to analyze it and decide what parts of it will be useful to mention in your academic paper. And only then will you be able to present a substantial overview of the scholarly articles, books, dissertations, etc. you use in your paper. At Emergencyessay.com, you can get a fast literature review writing help from the professional and talented writers. We hire only the most experienced and motivated writers. The secret of their success is the passion for writing and motivation to help students improve their writing skills.
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The main purpose of writing a literature review is to make an overview of the available information on a particular topic. It can be either a separate assignment or a part of your essay or thesis. This task gives your instructor an opportunity to assess your ability to conduct an effective research using relevant sources and evaluate each source critically indicating its strengths and weaknesses. Writing a review, you need to focus on a specific topic and discuss how good or bad the information on it is presented in all of the sources you mention. You should demonstrate that you've managed to critically analyze the sources and now have an objective and in-depth understanding of a particular problem. Clearly indicate what is known and what are the questions remaining to be unanswered. If you're writing a literature review as one of the chapters of your thesis, make an emphasis on the points that need further research and state which of them your work is going to contribute to.
You literature review should include the following points:
There are several points you have to pay close attention to when making a critical analysis. First of all, decide on whether this is a credible source. Does the author support his claims and conclusions with enough evidence? Can the scholars all over the world trust his point of view? Also, make sure the author is objective and writes not only in favor of a specific issue, but discusses the counterarguments as well. One of the most important points you should mention is whether this source is convincing enough. Did the author succeed in proving his ideas? And, finally, was this work helpful? Did you find some important and relevant information on the discussed topic that contributed to better understanding of it? Following this short plan and answering these questions will help you a lot in writing a substantial literature overview.
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Thumbay Group Hospitals are a state-of-the-art network of hospitals with the highest levels of patient and technology-driven care provided to people all across UAE and wider Middle East. This is done with the help of highly qualified professionals with a wide-ranging experience and expertise. Thumbay Hospital, Ajman is the Teaching Hospital of Gulf Medical University recognized by the Ministry of Health and Prevention, UAE for clinical and internship training. Nursing being an integral part of patient care the students will have the advantage to gain clinical training in all the hospital and clinics under the Thumbay group.
The Gulf Medical University and its Healthcare Division are both owned by the Thumbay Group which is unique to GMU. The establishment of the “Gulf Medical University Academic Health System” has allowed the integration of GMU’s triple mission of health professions education, research and clinical care at all levels.

domain: medical


Severe food crisis could be death sentence for Yemeni children
War, rising food prices, a health system overwhelmed by COVID-19 and funding challenges are deeply impacting access to food for children all across Yemen, pushing up the number of children who are on the brink of hunger or even starvation, Save the Children warned today.
Following a new UN report on malnutrition in the south of the country, the organisation is deeply concerned for the children in the north as well. In some clinics where Save the Children works, the number of malnourished children who came for life saving treatment rose by 60 percent between the end of last year and July 2020.
“The recent numbers released on southern Yemen should serve as a loud alarm bell. More children are likely to die across the country if the crisis is not taken on quickly. The deadly combination of war and hunger is pushing thousands of children closer to starvation every day,” said Xavier Joubert, Save the Children’s country Director for Yemen.
“Children in Yemen have become collateral damage in a war that has raged for more than five years. It is horrific to think that, in just half the country, almost 100,000 children under five are on the brink of starvation – malnourished to the point their lives are on the line. And numbers may be even higher across the whole country”, Mr Joubert added.
Save the Children continues to provide health and nutrition support for the most vulnerable children in Yemen, both in the north and the south of the country. In clinics in Hodeidah, the monthly average admissions of children suffering from severe or moderate acute malnutrition rose by 60 percent between March and July 2020, compared to the previous five months. Voluntary health workers identified a five percent rise of acutely malnourished children across communities they visited.
One such child was Amin*, a 15 month-old who was diagnosed with severe acute malnutrition – a potential deadly form. With support of Save the Children’s health staff, Amin recovered.
His mother, Jamila*, said: “We buy the most basic food items as the staggering increase in prices doesn’t allow us to get the amount of food we need. Bread and rice are the only items we buy and in some cases, we may buy some vegetables to improve the health of my son. It has become rare to find meat or fish in our meals.”
Save the Children said that the increasing number of children going hungry is a clear indication of the deteriorating food situation in the country. Yemenis are less able to afford food because of soaring prices. The cost of a food basket in northern areas has gone up by 2,400 YER ($4 USD) since January, while families were already struggling to hold their head above water. In the south, the minimum cost for a food basket has risen by YER 6,331 ($7.70 USD), which is 15% more than what it was in the 2018 crisis.
So far this year, Save the Children has provided 50,245 people, including 17,807 children, with food through household food baskets or cash transfers. The charity also supports pregnant and lactating women and offers breastfeeding and nutrition advice.
But shortages in funding have created a gap in life-saving programmes, meaning less children and families are receiving food assistance. This has increased the struggle children in Yemen are facing.
Save the Children calls on donors to step up their funding for life saving programmes in Yemen. It also calls upon all parties to the conflict to work towards a sustainable political solution, and for unhindered access to all areas by humanitarian organisations to those most in need.
*Names changed to protect identities.
We have (photo) content available, which you can find here.
For any requests or more information, kindly reach out to:
Ahmed Bayram, Ahmed.Bayram@savethechildren.org / +961 71 562 855
Faiz Jamil, email@example.com / +44 7542 596542
Out-of-hours: Media@savethechildren.org.uk / +44 7831 650 409
 Yemen Minimum/Survival Food Basket for average household of 7 members per month (Prepared and adopted by FSAC partners) : 75kgs wheat flour, 10kgs dry weight beans, 8 liters cooking oil, 2.5 kgs sugar and 1kg iodized salt.
 Details of food basket contents can be found here: https://fscluster.org/sites/default/files/documents/fao_fsts_market_monitoring_bulletin_july_2020_en.pdf


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Table of Contents
Gaming has always been a huge stress buster for us; An escape from the real world that takes you to the world of racing cars, fighting demons, and treasure hunters. And Sony’s PlayStation 4 remains the unbeaten king as the best platform for you to enjoy the best gaming experience.
There are literally thousands of games for PS4 out there, but we have handpicked the very best for you to have that stellar gaming experience. Each game represents a genre or has a specialty that is best in class. You can choose which one suits the best for you.
There are some other factors as well, which can enhance your gaming; for example, a 4k tv can increase in-game performance a lot, and earphones with heavy bass can exemplify every gunshot in the game. You can check out Best 4K tv in India and Best earphones with Bass in India. That said, let’s start our list:
Best Games for PS4
Grand Theft Auto 5
If you like a game that does it all, GTA 5 is for you. Launched back in 2013, it still remains the most played game on PS4 after 8 years. GTA 5 includes racing, heists, gunfights, car-chase, and a lot of violence. The map on this game is huge, as there are a lot of places to be discovered. The graphics are top-notch as well, and the GTA online brings a whole new world to your character.
God of War
God of war is practically Gods fighting with each other with all the superpowers one can imagine. This game has the most engaging storyline of a father (Kratos) and his son (Atreus) learning and fighting their way out. The combat system is easy to learn but hard to master and the power-ups are gradual throughout the game. Violent at times, this game offers the best experience one can get out of an action game.
This game is one of the most grossing in the Online Battle Royal games genre. Its gunplay, movement, and strategy execution feel much better than other similar games.
Apex Legends has an excellent ping system, and players can interact in an incredibly detailed world. If you like online multiplayer, we are sure you’re going to love Apex legends.
Gran Turismo Sport
This one is for all the racing lovers. The Grand Turismo has existed since the original PlayStation for its flagship racing game DNA. It features high-level driving assistance for those who want to assist in steering, throttle control, and stability control, making it easy for amateur players. Its online mode is competitive as well as fun to play.
Assassin’s Creed Odyssey
This is the newest edition in the Assassin’s Creed franchise. It’s an open world with beautiful graphics and an intensively responsive map. Except for the main story campaign, there are a ton of things you can do. The fighting feels fresh though you can find similarities if you have assassin creed games before.
Red Dead Redemption 2
This game takes you to the world of the wild west. It is filled with Icy mountains, open fields, gushing rivers, gunslingers, and horses. Red Dead Redemption is a realistic game that you can play on PS4 because of its brilliant graphics and gameplay. The primary campaign is intensively intuitive, and after finishing that, you can explore its huge map and travel through different terrains on your horse.
Fifa has been producing the best football games for a long time, and FIFA 20 is no exception. You can play with your favorite club from around the world with your friends. The story mode is exciting and engaging, as well. This time FIFA has introduced a new Volta mode, which is similar to street football. Also, Fifa Ultimate team remains a strong aspect of the game, which lets you build your own team from the ground up.
This game is one of the few superhero games that performs wonderfully. The story takes you in the life of peter parker and how he takes out the bad guys in new york city. The combat gameplay and upgrades are brilliant throughout as you get different suits with special features as you progress further. The graphics, too, are excellent.
Some Honourable Mentions:
- Witcher 3
- Horizon Zero Dawn
- The Last of Us
- Uncharted 4

domain: game


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In a booking photo provided by the Dearborn, Mich., police department, Roger Stockham is shown. Stockham, of Imperial Beach, Calif, was arrested on Jan. 24, 2011 outside the Islamic Center of America mosque in Dearborn, Mich. Stockham was arraigned Wednesday on charges of making a false report or threat of terrorism and possessing explosives with an unlawful intent. (AP Photo/Dearborn Police, HO)
Hours before he was arrested on the suspicion he was plotting to blow up a popular Detroit-area mosque, a California man told people at a nearby sports bar that he planned to set off a "big explosion," bar employees said Monday.
Joe Nahhas, a manager at the J.S. Fields bar in Detroit, told The Associated Press that a man later identified as 63-year-old Roger Stockham ordered a Scotch on Jan. 24 and told him he planned to cause an explosion that would be "here, there, the mosque."
Nahhas said he called 911 to report the incident, and police have said a tip preceded Stockham's arrest near the Islamic Center of America in neighboring Dearborn a few hours later.
"My honest belief is he was having a celebration before hurting people," said Nahhas, whose bar is down the street from the mosque, one of the largest in North America.
"I realized this guy means business," he said.
When officers pulled him over, Stockham, of Imperial Beach, Calif., was wearing a ski mask and driving around with powerful Class-C fireworks, which are illegal in Michigan, Dearborn Police Chief Ronald Haddad said Monday. Police earlier said Stockham was arrested in the mosque parking lot, but said Monday he was actually arrested on a street nearby.
Investigators also found open alcohol containers and spray paint in Stockham's car, police said in a statement.
Dearborn Police Chief Ronald Haddad said Sunday that authorities believe Stockham was acting alone in the plot against the suburban Detroit center but still take him "very seriously." He was arraigned Wednesday on one count of making a false report or threat of terrorism and one count of possessing explosives with an unlawful intent.
"I was comfortable with the fact that we had taken him off the street -- he isn't going anywhere," Haddad said. "I think the society he wanted to impact is safe."
Court documents in Vermont show Stockham pleaded not guilty by reason of insanity to charges stemming from threats made in 2002 against the U.S. president and against veterans' facilities in that state. Stockham was charged after officials say he threatened employees at a Veterans Administration hospital in White River Junction, Vt., and at a veterans' center in South Burlington, Vt. He allegedly threatened the murder the president -- who at the time was George W. Bush -- saying he was going to "whack the bastard."
According to Thomas Zonay, an attorney who represented him at the time, Stockham was committed for a psychiatric examination at the U.S. Medical Center for Prisoners in Springfield, Mo., for four months in 2005 and was found to have bipolar disorder, post-traumatic stress disorder and personality disorder. The U.S. Bureau of Prisons says Stockham was released from custody that year.
Haddad said he called the Islamic Center's leader early Tuesday to let him know of the arrest. He later met with Imam Hassan al-Qazwini and mosque board members, who he said shared concerns about copycat crimes if the arrest was publicized, and Haddad said he understood.
"We never want to put something out there that gives someone the `how-to,"' Haddad said.
Qazwini informed worshippers about the incident during his sermon Friday. The Council on American-Islamic Relations' Michigan chapter issued a news release Saturday night and the police followed Sunday morning.
Stockham remained jailed Sunday on a $500,000 bond. A preliminary examination is scheduled for Friday.
Police didn't know whether Stockham had an attorney. A public records search did not turn up a listed number for Stockham, though Haddad said he lives in Imperial Beach, near San Diego.
Landon Debono, a 24-year-old Navy veteran who is neighbor's with Stockham, said Stockham put forth a happy face but seemed troubled.
"I think he suffered from PTSD," said Landon.
At a small two-story apartment building in Imperial Beach that records show as Stockham's last address, resident Landon DeBono said Stockham moved out three or four weeks ago, and said something about being in trouble.
He said Stockham kept to himself, and has a scar on his neck from a suicide attempt almost a year ago. Debono said he was friends with Stockman's ex-girlfriend, and that he would see Stockham regularly at the local Veterans of Foreign Wars bar.
"He was always at the bar," he said. "He was a very likeable, good guy. I wouldn't think he'd be capable of doing something like this. It's pretty trippy, kind of weird he was living right there. I never thought him to be a violent person."
Dearborn, located about 10 miles west of Detroit, is the capital of the Detroit area's Arab-American community, which is one of the largest in the U.S. A third of the city's 100,000 residents trace their roots to the Arab world.

domain: news


Leedon Green is the latest luxury freehold development in Singapore’s trendy Central Business District (CBD). The project is located on land previously used for agricultural purposes. The project is managed by Singapore Technologies for the supply of sustainable, environmentally responsible and energy efficient property. Leedon Green is located within walking distance to Singapore Zoo, the Singapore Botanic Gardens, and the Singapore Art Museum. The project promises to be Singapore’s next premier lifestyle development and is being designed by award winning architects Koffler Architects.
The Leedon Green condominium is a distinctive freehold residential development on the basis of the former tulip garden site. Here explore the key features of this project, as well as competitive market prices of similar products on the same site. Leedon Green is renowned for its award-winning architectural designs, as reflected in the building’s design award-winning credits. The mixed use of the triangular site and its multi-storey buildings will provide residents with ready access to the retail, restaurant and entertainment facilities which are a standard feature in Singapore’s up-market real estates.
Leedon Green boasts some of the most innovative and technologically advanced retail and lifestyle offerings in Singapore. Retailers such as Maxico and Pottery Barn are located on Yanyang Terrace, while chains such as Forever 21 and The Outlet Mall are located on Yanyang Avenue. Leedon Green also includes retail facilities for clothing boutiques such as Pottery Barn. Leedon Green is also home to a range of serviced apartments, and residents can benefit from easy public transport links to nearby destinations. Singapore’s public transportation system includes the MRT, while the monorail network runs through the Singapore River.
Leedon Green offers a diverse selection of Singapore property for sale, and residents will be spoilt for choice when it comes to picking out their ideal residence. Whether they wish to opt for a two-bedroom unit or a spacious three-bedroom unit, residents can have their pick of all the amenities offered by these Singapore properties. Two-bedroom units come in two to three bedrooms, with en-suite bathrooms and private balconies, making them ideal for families. The total area of these Singapore residences is approximately four thousand square feet, including the garage.
A three-bedroom unit in Leedon Green is just right for a couple wishing to enjoy both city life and country life in the same location. A Singapore real estate condominium offers a more traditional lifestyle with two to three bedrooms in a fully furnished unit. Residents can further enhance their homes with additional features such as a garage, porch and sun terrace. Most Singapore real estate condominiums come with a monthly rent as low as $1350, making this a perfect home for retirees, those who are looking for a cheaper way to enjoy the perks of home, or young couples who are on a tight budget.
The Leedon Green Shopping Centre is just steps away from residents as well as visitors to the Leedon Green area. Located at the corner of Yanyang Road and Melville Road, the Leedon Green Shopping Centre promises to offer visitors an unparalleled shopping convenience. Located within walking distance of many of Singapore’s popular night spots, the Leedon Green Shopping Centre is also ideal for those who wish to indulge in some wholesome food and beverages. The Leedon Green Shopping Centre is Singapore’s first multi-level shopping centre. Its resident proprietors strive to maintain an environment that not only provides a delight for shoppers, but one that also preserves Singapore’s heritage and regional charm.
Leedon Green is also the right place for investors who wish to relocate into the Leedon area of Singapore. Though not completely detached from its urban centre, the residents of this neighbourhood enjoy all the benefits of being close to the business centres of the city, while still being in close proximity to Singapore’s natural beauty. The mixed and matched housing estate offerings here ensure that the residents of this neighbourhood will always have a great choice when it comes to choosing a home. In addition to the traditional homes, the real estate offered here offers an array of condominiums and other residential choices.
With the growth rate of urbanisation fast catching up with most countries, Singapore’s population is set to continue to grow in size. To cater to this growing need, more people are opting to stay closer to their places of work, thus driving up the demand for real estate in Singapore’s metropolitan areas. Leedon Green is one of the best-performing areas in Singapore, offering prime opportunities to both job seekers and property buyers. For these reasons, it is no surprise that more real estate developers are lining up in Leedon Heights Green to develop more residential estates in this area of Singapore.


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Background and Aim: The incidence of non-alcoholic fatty liver disease (NAFLD) is increasing all over the world. NAFLD develops in patients with liver disease, including patients with autoimmune hepatitis (AIH). NAFLD and AIH have some similar laboratory and histological findings. The aim of this study was to elucidate the characteristics of AIH patients with NAFLD. Methods: We re-evaluated the nationwide survey performed in Japan in 2015 of AIH patients diagnosed between 2009 and 2013. Results: A total of 1151 subjects (144 men and 1007 women) were enrolled in the present study. The overall prevalence of NAFLD was 17.0%. Compared to AIH without NAFLD, AIH patients with NAFLD had the following characteristics: (i) low female-to-male ratio, (ii) older age, (iii) mild elevation in hepatobiliary enzymes, (iv) histologically progressive fibrosis and mild plasma cell infiltration or mild lobular hepatitis, (v) lower prevalence of prednisolone administration and higher prevalence of ursodeoxycholic acid administration, (vi) higher levels of hepatic enzymes and immunoglobulin G after treatment, and (vii) similar prevalence of autoimmune and malignant complications. Conclusion: AIH patients with NAFLD have many features that are different from AIH patients without NAFLD. Understanding these differences is essential for the proper diagnosis and treatment of AIH patients with NAFLD.
ASJC Scopus subject areas


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Become a Member
Sign the Petition
Please sign the petition hosted by Prairie Rivers Network.
Stand Up To Coal is dedicated to informing residents, farmers and landowners in Champaign and Vermilion Counties, IL about the negative effects that Sunrise Coal, LLC's planned coal mine could have on our lands, waters and health.
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At Tuesday’s meeting of the Vermilion County Board, farmers and rural residents boarded a bus to Danville to call on board members to send a strong message against coal mining in Vermilion County by passing a resolution to protect local … Continue reading
Show your support for Stand Up To Coal at the March 8th meeting of the Vermilion County Board. Group members will discuss Sunrise Coal LLC’s plan to mine coal in Vermilion County, and how a new mine could threaten agriculture, … Continue reading


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Student Voices, Student Vote: Democracy in Action at Brookes Westshore
Wednesday, October 17, 2019, VICTORIA, CANADA: Local candidates across Esquimalt, Saanich and Sooke took to the hustings in an open All-Candidates Debate held at Brookes Westshore on Wednesday in the build-up to the federal election next week. Brookes Westshore students from across grades 6-12 posed their questions to candidates from the Liberal Party, the NDP, the Green Party, the People’s Party and the Communist Party. The local candidates fielded questions on a wide range of topics – from the environment to human rights, and from tax policy to immigration.
“We are delighted to offer our students the opportunity to engage with the democratic process here in Canada,” said Head of School Jerry Salvador, “Here at Brookes we place value and focus on building community.”
Jerry continued, “Watching our respected candidates’ voice their stances, here on the Brookes campus, and watching our students connect their learning to a local political context has been a rewarding experience for us all and a great way to connect with our community.”
Brookes Westshore is an International Baccalaureate (IB) World School home to over 120 twenty boarding students from more than 20 different nations around the world and more than eighty local day students.
Clear from the questions being posed by students, environmental sustainability is high priority for students at Brookes Westshore.
“It is so important that we take action on the climate crisis,” says Tristan, Grade 10, Brookes Westshore, “I really wanted to hear what each party is going to do to make sure our environment is protected.”
One candidate in particular was surprised (and delighted) to learn that a future leader of his party was in the audience. Sam, a Grade 6 student, was determined to announce his stated ambition to lead the Green Party one day.
The candidates meeting will be followed on Friday with a full-scale mock election – the culmination of Student Vote activities at Brookes Westshore. Student Vote is a nationwide program that over one million students participate in to become educated in governance and politics, cast their votes, and encourage active civic engagement as students transition to adulthood (see https://studentvote.ca/canada/ for more details).
James Boxshall: email@example.com
[t] 250 893 6938


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Mechanism of Tumorigenesis by Cancer-Associated Mutations of INI1/SMARCB1, a Component of the SWI/SNF Chromatin Remodeling Complex
MetadataShow full item record
One of the core components of the chromatin remodeling complex SWI/SNF that are frequently mutated in human cancers is INI1/SMARCB1. Some of INI1/SMARCB1 mutations, found in rhabdoid tumors-RT (S284L, P48S) and schwannomatosis-SW (PI4H, R53L), are cancer-associated (CA) missense mutations expressing stable full-length INI1/SMARCB1. Since the reintroduction of INI1/SMARCB1 into RT cells have shown to induce cell cycle arrest, senescence, and transcriptional dysregulation of a few downstream genes, we hypothesized that these CA-INI1/SMARCB1 mutants could be defective for one or more of those functions, resulting in tumorigenesis in RT and SW. Therefore, we analyzed the physiological and transcriptional changes of RT cells upon the reintroduction of INI1/SMARCB1 or CA-INI1/SMARCB1 mutants and found that some but not all CA-INI1/SMARCB1 mutants were defective for inducing cell cycle arrest. However, they were all defective for inducing senescence and three out of four were defective for activating GBP1 (guanylate binding protein 1). We further confirmed that the ectopic expression of GBPI in RT cells can induce senescence in the absence of INI1/SMARCB1, and INI1/SMARCB1 requires GBP1 for a fully effective induction of senescence in RT cells. These evidences, for the first time, showed that the evasion of senescence was a mechanism by which CA-INI1/SMARCB1 mutants generated tumors.;To further understand the mechanism behind the inability of CA-INI1/SMARCB1 mutants to regulate transcription and induce senescence, their interaction with cMYC, a major known transcription factor deregulated in many cancers, and an important binding partner of INI1/SMARCB1, was tested. All CA-INI1/SMARCB1 mutants were found to be defective for interacting with cMYC, as well as for the repression of a few cMYC downstream transcription factors, including FOXM1 (forkhead box protein M1), a major mediator of cell cycle progression. Treatment of RT cells with CDK4/CDK6 inhibitor PD0332991 drug, which would target FOXM1 phosphorylation, led to the inhibition of cell proliferation, G2 cell cycle arrest, and induction of senescence. These studies, for the first time, indicated that CA-INI1/SMARCB1 mutants were defective for regulating cMYC and that interfering with activation of a cMYC target, FOXM1, was a novel strategy to inhibit tumor cell growth and induce senescence in RT cells.
Source: Dissertation Abstracts International, Volume: 75-07(E), Section: B.;Advisors: Ganjam V. Kalpana.


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Those in the trade with memories of the UK Jewellery Awards are still being encouraged to enter this year’s #UKJA25 social media competition as the event prepares to mark its silver anniversary this year.
Entries can be made across Facebook, Twitter and Instagram and is a way for the industry to share its memories of the awards over the last 25 years.
Anyone can post an image or a memory from UKJA ceremonies in years gone by using the #UKJA25 hashtag.
The best posts will be featured by Retail Jeweller in the lead up to this year’s silver anniversary ceremony on June 29 and an overall winner will be selected to receive a prize on the night.
Often dubbed the industry Oscars, the UKJAs are the only awards for the industry judged by the industry and remain to this day the most prominent and well recognised accolade in the trade.
Over the last 25 years, the awards ceremony has firmly cemented itself as the leading industry event to celebrate the achievements of all aspects of the trade, from designers through to suppliers, brands and retailers.
Retail Jeweller editor Ruth Faulkner explained: “This year sees the landmark silver anniversary of these high-profile awards, first launched back in 1992. It is a remarkable achievement to still be delivering the industry with such a fantastic platform for profiling its successes after so many years and we are keen to share the achievements and memories of those who have enjoyed attending this wonderful event.
“We know there must a huge number of you in the trade with memories to share from years gone by at the UKJA – photographs, winners’ trophies and definitely the odd story – and we look forward to reliving some of these memories with you.”
#UKJA25 is open from now and, over the coming weeks, Retail Jeweller will also be sharing some of its favourite memories from past awards.
The 25th anniversary edition of the UK Jewellery Awards, in association with Clogau, takes place on June 29 at London’s Hilton Park Lane. For more information please visit awards.retail-jeweller.com .


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Tuesday, May 21 2013 6:32 PM EDT2013-05-21 22:32:47 GMT
(ABC News)--Frown lines, forehead creases and crow's-feet, oh my! If the rise in Botox procedures is any indication, the fountain of youth might be found in a syringe, even for 20-somethings whoseMore >>
Frown lines, forehead creases and crow's-feet, oh my!More >>
Tuesday, May 21 2013 5:47 PM EDT2013-05-21 21:47:01 GMT
Richmond, VA—As 8News continues its investigation into the allegations against The ROC Church pastor Geronimo Aguilar who is accused of having sex with minors in Texas, another woman has come forward with allegationsMore >>
8News has learned that Texas authorities confirm Geronimo Aguilar is in custody, after surrendering without incident at his home in Richmond Tuesday afternoon. Two warrants had been issued for Aguilar's arrest earlier in the week...More >>
Tuesday, May 21 2013 4:04 PM EDT2013-05-21 20:04:26 GMT
Richmond, VA—A teenage Varina High School student is facing several charges, after police say he abducted another student from the parking lot of the school Monday morning at gunpoint. On May 20 at aboutMore >>
A teenage Varina High School student is facing several charges, after police say he abducted another student from the parking lot of the school Monday morning at gunpoint...More >>
Tuesday, May 21 2013 12:32 PM EDT2013-05-21 16:32:22 GMT
Search-and-rescue crews worked through the night after a monstrous tornado barreled through the Oklahoma City suburbs, demolishing an elementary schoolMore >>
Search-and-rescue crews worked through the night after a monstrous tornado barreled through the Oklahoma City suburbs, demolishing an elementary school and reducing homes to piles of splintered wood. At least 24 people were killed, including at least seven children, and those numbers were expected to climb.More >>
CULPEPER, Va. (AP) - Attorneys for a former Culpeper police officer convicted of manslaughter are seeking a mistrial.
They say jurors who convicted Daniel Harmon-Wright in the fatal shooting of an unarmed woman consulted a dictionary to guide their deliberations on the meaning of "malice," indicating they were confused about jury instructions, according to media reports.
The trial judge adjourned Wednesday's scheduled sentencing until Friday to hear from opposing attorneys on the matter.
Jurors on Tuesday convicted Harmon-Wright of voluntary manslaughter in the Feb. 9, 2012, death of Patricia Ann Cook. He claimed he shot Cook after she attempted to drive away in her vehicle with his arm caught in the window.
(Copyright 2013 The Associated Press. All rights reserved.)
CULPEPER, Va. (AP) - A jury in Culpeper has found a former police officer guilty on three counts including manslaughter in the shooting death of an unarmed woman.
WVIR-TV in Charlottesville (http://bit.ly/127Esny) reports that jurors Tuesday returned the verdict against Daniel Harmon-Wright in the Feb. 9, 2012, death of 54-year-old Patricia Ann Cook.
The 33-year-old Harmon-Wright has testified that he shot Cook after she trapped his arm in the window of her vehicle and dragged him.
A prosecutor called the fatal shooting "excessive" and unnecessary.
Jurors return Wednesday for the sentencing phase of the trial.
Copyright 2013 by The Associated Press. All rights reserved.


text:
talk 'Machine learning for precision medicine'
- seminar, organized by BIG-N2N
- where? J. Schell seminar room, UGent-VIB Research building FSVM, Technologiepark 927, 9052 Zwijnaarde (Gent)
- when? Tuesday March 7, 11:00 - 12:00
Jean-Philippe Vert is professor at the Department of Mathematics at Ecole normale supérieure of Paris, France, director of the Centre for Computational Biology (CBIO) at MINES ParisTech, and team leader at Institut Curie, Paris, France. He graduated from Ecole Polytechnique and has a PhD in mathematics from Paris 6 University. His main research interest is in machine learning and its application to biology, particularly cancer research.
The development of DNA sequencing technologies allows us to collect large amounts of molecular data about the genome of each individual, and opens the possibility to predict drug response or evaluate the risk of various diseases from one's molecular identity. It also raises statistical and computational challenges, as the quantity of data collected per sample is usually far larger than the number of samples available to estimate predictive models. In this talk I will discuss some of these challenges and describe a few methods to attack them through regularization or change of representation, illustrated on applications in cancer prognosis and drug response prediction from gene expression and somatic mutations.


text:
Students will develop an understanding of the concepts of geography and how it has impacted the development of cultures. Our focus for this unit will be the Middle East and the North Africa region.
Students will look at how cultures have borrowed from each other. This period serves as a useful example of what happens when cultural diffusion takes place. The highlighted civilizations in this unit are
Greece and Rome, followed by the time periods of the Middle Ages and the Renaissance.
Cultures in Transition
Students will be introduced to the Latin American and African regions. These regions have been hindered by struggling economies and unstable governments. Students will discover that these regions’ development can largely be attributed to a history of European colonialism and imperialism.
Conflict and Cooperation
In this unit, students learn about the challenges of the 20th Century, including World War I, World War II, the Russian Revolution, and the Cold War. They also learn that compromise is essential for creating and maintaining a balance of power among nations and the role of global organizations such as the European Union and United Nations.
The Global Interdependence unit concludes the 6th grade study of people of places in the contemporary world. China and Japan receive the most emphasis in this unit of study but other major countries from the Pacific Rim are also discussed. This concluding unit demonstrates that cultures are now more globally connected than in the past.

domain: geography


text:
Me and my girl
First ever Weetbix Tryathlon. Loved it. Rocked it
A picture a month of the kid as she grows over the year.
Christmas day sprinkler fun.
A year done. Probably not really the best selection I could have come up with but 2017 was not the year of pictures. Hopefully 2018 will be better.
Waiting her turn to dance. The dance school production of Peter Pan.
At home in the woods
July has flown past with few pictures being taken by me. Motel living, house purchasing and furnishing and all that goes with it. We enjoyed a slowing as we settled into our new home and the kid was able to relax and unwind. I think we all have.
© 2018 Small Steps Big Noises | Theme by Eleven Themes

domain: artistic


text:
Fossils In Jasper Stone Posters
Fossils In Jasper Stone Posters is highly bewitching and makes a perfect wall decoration, this unit dimension is 18 x 12 inch and the price is $29.99. If you're trying to ask for top recommended Fossils In Jasper Stone Posters with cut-price price, this produce is the nice deals for you.
Type: Premium Poster
Dimension: 18 x 12 inch
A vertical format poster, measuring , on climactic paper with blank area at top for clients and playdates. The exquisite quality paper and this poster is crisp and clear and just fantastic. For only $29.99 it would be a inexpensive poster, the peculiarity is electric. It is faithful quality and size for the low-cost price.
The colors are highly amazing, and Fossils In Jasper Stone Posters will be a noticeable eye catcher wherever you decide to display this unit. DirkWiersma cool artwork has delighted untold a great deal of collectors on the place. The colors are simply attractive, this poster was such a low-priced price. The item is recieved within specified time and reliable packaged desirable this poster was exactly as described. Fossils In Jasper Stone Posters is an easy read even if you're just a little curious about the poster.

domain: design


Break the Dengue Transmission with Indoor Mozzie Repellent Cream
Even as you stay at home for safety during the Circuit Breaker, you need to deal with yet another health concern brought by Dengue, one of the most prevalent mosquito-borne diseases. As the Dengue peak season approaches, you will have to proactively implement protective measures, especially if you live in dengue clusters or landed residential areas.
Residents now face a higher risk of Dengue transmission due to the virus’ shorter incubation period, as well as the accelerated breeding cycle of the Aedes mosquito. According to National Environment Agency (NEA), in the week ending 16 May 2020, there were 529 dengue cases reported, which is higher than the 300 to 400 weekly cases for the first four months of this year.
While this data is alarming, keep in mind that there are a lot of ways to avoid this dreaded disease. Aside from protecting yourself from the virus, you can contribute to putting an end to the vicious circle of Dengue transmission by practising preventive measures while inside your home.
The Need to Break the Dengue Chain of Transmission
It is a known fact that bites of infected female mosquitoes, primarily the Aedes aegypti mosquito, transmit the Dengue virus to humans. What’s worse, when an infected mosquito feeds on a Dengue-infected person, the virus replicates in the mosquito’s midgut. In about 8-12 days from the time the virus was ingested, the mosquito can transmit the virus to a new host.
On the other hand, human-to-mosquito transmission is also possible. When bitten by an uninfected mosquito, an infected person can transmit the Dengue virus to the mosquito. This transmission may occur up to 2 days before a person shows symptoms and up to 2 days after the Dengue fever has resolved. When the virus makes its way to its salivary glands, this mosquito can then infect human hosts.
Breaking this continuous cycle of Dengue transmission is the best way to prevent more and more people from acquiring the disease. One of the measures that can effectively stop this transmission chain is for people to make mosquito repellent application a habit.
Figure: The Dengue Chain of Transmission
Protect yourself and stop the transmission cycle by applying mosquito repellent
Aside from spraying insecticides and doing regular mozzie wipeouts inside homes, NEA highly recommends applying mosquito repellent daily even when you are staying indoors. Mosquitoes may breed even in your home, especially if you live in a dengue cluster.
More so, if there are people infected with Dengue in your area, there is a risk of having more infected mosquitoes that may carry the virus into different homes. Thus, NEA also recommends that even people who are suspected of having Dengue or those already infected with the Dengue virus should apply mosquito repellent regularly.
NEA highly recommends applying mosquito repellent daily even when you are staying indoors
DEET as the most effective ingredient in repelling mosquitoes
There are many types of mosquito repellent available in the market nowadays. From lotions and sprays to creams and impregnated repellent materials, you can choose from a wide array of options based on what’s convenient for you to use. You will also need to select a mosquito repellent according to its ingredients — DEET, Picardin, Eucalyptus, and Citronella.
With the many options to choose from, you might be confused on what to use. The key is to find which is most effective in terms of repelling mosquitoes. According to the U.S. Centers for Disease Control and Prevention, repellents that contain DEET (chemical name N, N-diethyl-meta-toluamide) offer the best protection against mosquito bites. In theory, DEET can interrupt the receptors in the mosquito’s antennae, which makes it hard for the insect to locate humans.
U.S. CDC – Repellents that contain DEET (chemical name N, N-diethyl-meta-toluamide) offer the best protection against mosquito bites
Despite the fact that DEET is most effective when it comes to repelling mosquitoes, some have the impression that DEET may be too harsh for them. However, a study conducted by the Canadian Institutes for Health Research states that DEET-based insect repellents are relatively safe when used as recommended. The study also suggests that a mosquito repellent containing 10% DEET can provide a longer period of protection than other repellents, based on a one-time application comparison.
Likewise, a laboratory evaluation conducted by Vector Control Research Unit of Universiti Sains Malaysia found out that a mosquito repellent with 10% DEET has 66% longer protective efficacy against mosquito landings compared to a citronella spray with 15% concentration.
Ceramoz® has 10% DEET and provides 66% longer protective efficacy against mosquito compared to a citronella spray with 15% concentration
NEA-approved mosquito repellent with moisturiser
A product approved by NEA as a general use insect repellent is Ceramoz® Mosquito Repellent Cream. Ceramoz is uniquely formulated with DEET, which is scientifically proven to repel mosquitoes up to 66% longer than citronella repellent.
Unlike other mosquito repellents, Ceramoz moisturises the skin as it repels mosquitoes. Suitable for all skin types, it contains ceramide-dominant 3:1:1 lipid ratio formulation, which is essential in maintaining the skin barrier function and retaining skin moisture.
Additionally, Ceramoz mosquito repellent is safe to be used on babies 2 months onwards and pregnant women. This hypoallergenic mosquito repellent contains only 10% DEET and is free of paraben, fragrance, and colourants.
Don’t let down your guard during the Circuit Breaker. The risk of Dengue transmission is high even when people are just staying inside their homes. As you remain indoors for safety, make sure to practice preventive measures like applying mosquito repellent. Making it part of your daily hygiene routine will protect not only you but also your loved ones and the people around you. It is a crucial step towards breaking the cycle of Dengue transmission.
DEET-based insect repellents: safety implications for children and pregnant and lactating women by Gideon Koren, Doreen Matsui, Benoit Bailey of Canadian Institutes for Health Research
Fight the Bite for Protection from Malaria Guidelines for DEET Insect Repellent Use by Centers for Disease Control and Prevention – Department of Health & Human Services – USA
Contact Dermatitis Due to Oil of Citronella – The Journal of Investigative Dermatology


text:
2 dead bottlenose dolphins seen near large fishing fleet off Spanish coast prompting fears that they were likely to have been incidentally caught in the fishing nets.
From the P&O Cruise Ferry, the Pride Of Bilbao, The Biscay Dolphin Research Programme (BDRP) has gathered a great deal of data on the distribution and abundance of whales & dolphins (collectively known as cetaceans) in the European Atlantic. This unique year round database has demonstrated the importance of this area as a feeding and breeding ground for many different species with more than a quarter of all cetacean species being recorded in the area.
On a recent crossing of the Bay of Biscay in April 2005, not far from the port of Santurtzi on the Northern Spanish coast, Clive Martin, BDRP Director and the Senior Wildlife Officer on board the Pride of Bilbao, observed a huge fishing fleet of Spanish vessels. On closer inspection, Clive could see bottlenose dolphins (Tursiops truncatus) amongst the fishing fleet together with associated long finned pilot whales (Globicephala melanea).
Adrian Shephard | alfa
Scientists produce a new roadmap for guiding development & conservation in the Amazon
09.12.2016 | Wildlife Conservation Society
Successful calculation of human and natural influence on cloud formation
04.11.2016 | Goethe-Universität Frankfurt am Main
Physicists of the University of Würzburg have made an astonishing discovery in a specific type of topological insulators. The effect is due to the structure of the materials used. The researchers have now published their work in the journal Science.
Topological insulators are currently the hot topic in physics according to the newspaper Neue Zürcher Zeitung. Only a few weeks ago, their importance was...
In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.
Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...
Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
16.11.2016 | Event News
01.11.2016 | Event News
14.10.2016 | Event News
09.12.2016 | Life Sciences
09.12.2016 | Ecology, The Environment and Conservation
09.12.2016 | Health and Medicine

domain: biology


text:
Open Access Graduate Research Paper
School administrators--Attitudes; Teacher-administrator relationships; Student-administrator relationships;
The administrative leader not only has responsibilities for his/her own actions, but is equally responsible for the actions of many others including teachers, students, cooks, secretaries, teacher associates, and custodial staff. All of these workers are under the administrator's direct supervision, which makes it nearly impossible for him/her to know what everyone is doing, when they are doing it, and why they attempt to do it. However, what seems like such an enormous task is also the reason that administrative leadership is so exciting and challenging.
I will highlight what I perceive to be the critical elements of being an effective school principal. In doing so, I hope to share my values and philosophies of education, and share with you my vision of a quality school.
Year of Submission
Master of Arts in Education
Educational Leadership, Counseling, and Postsecondary Education
Robert H. Decker
1 PDF file (15 pages)
©2000 J. Lewis Curtis
Curtis, J. Lewis, "A vision for administering elementary schools : a reflective essay" (2000). Graduate Research Papers. 372.

domain: literature


Big time comfort in a stylish silhouette, our Becksa™ Short is the best of both worlds. Beloved for its unmatched comfort, flattering fit, and shape retention—the oh-so-soft ribbed fabric of our Becksa™ collection looks and feels fantastic both in and outside of the studio.But beyond that bestselling fabric, this always-on-trend biker silhouette has major crossover appeal too. Pair it with the Becksa™ Bralette for a cool matchy matchy look or with a slouchy sweater for a stylish-yet-sporty vibe. You've got options here!
Wide waistband with hidden key pocket
High rise – Fitted
Fair Trade Certified™ Factory
Black solid and Dream Dust Alotta Dots colorway: 86% Recycled Polyester | 14% LYCRA® Elastane; All other colorways: 42% Recycled Polyester | 42% Polyester | 16% Elastane
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Spiral is an AI solution that scans customer feedback and support data to detect emerging customer-facing problems before they blow up.
While you can check out our values here, in short, we’re a team of creative, passionate, and collaborative problem solvers. We all exchange friendly, honest feedback daily because we believe we have a lot to learn from one other. Coaching and preparation are also key to our success. And the best idea wins – always!
Our mission is to make every company in the world customer-centric.
Many companies receive a staggering amount of customer feedback every day – so much that no human could fully comprehend it all by hand. Product managers either attempt to manually scan through thousands of reviews and customer conversations or, surprisingly often, this information is just never used. Spiral, on the other hand, scans all customer feedback in minutes using AI and provides product managers and customer support leaders with specific problems that directly impact customers. This enables businesses to fix the problems that matter most, creating a better product and a happier customer. Founded by two former Amazonians, Spiral takes customer obsession to the next level. It provides companies with a scalable solution that shows the true north of what customers want, boosting the company’s revenue and customer satisfaction. Spiral has raised from world class investors such as Trilogy Equity Partners, Bezos Expeditions, Techstars, Amazon Alexa Fund, Alumni Ventures Group, and others.
If you are driven, aren’t scared to own a large component in our stack, are excited to experiment with crazy ideas, learn quickly, and would love to join a promising early-stage startup, come join us at Spiral to help thousands of companies make sense of their customer feedback!
We'd love to hear from you if you:
- Have demonstrated proficiency applying machine learning to meet business goals.
- Have had proven and recurrent success in designing, developing, implementing, and iterating on machine learning models.
- Have strong experience designing and working with data pipelines and distributed systems.
- Have experience successfully leading complex engineering and ML projects.
- Are proficient in writing production code in one or more modern languages.
- Love to write clean, well-factored, maintainable code and work with others to do the same.
- Thrive when there is variety and breadth in your work.
- Take satisfaction in owning big projects and developing new paths forward, and find that it’s worth the tradeoff of managing added ambiguity and messiness.
- Are open, collaborative, and flexible with others.
- Contribute to making decisions and move forward collaboratively after decisions are made, whether or not your approach was the one taken.
- Equally enjoy learning and teaching, and have the ability and enthusiasm to coach and mentor others.
- Have experience working with a team to decide when to optimize for speed versus robustness depending on the specific context.
- Are proficient in working on modern web applications, including API and database interactions.
- Have experience with best practices in software engineering domains such as CI/CD, infrastructure as code, automated testing, monitoring production environments, build and deployment of multi-package systems.
- Have enough experience as a software engineer and with ML to be considered “senior” (as described by some of these other items). That probably means you’ve been in a software engineering position for at least three years, but that isn’t a rigid requirement.
It’s a bonus if you:
- Have prior experience working as a software engineer at a startup and enjoyed it.
- Code fluently in Python, React, and/or Typescript.
- Are proficient with a variety of AWS architectures and services.
- Have experience working with a fully distributed/remote team.
- Are eager to add more custom emojis to our Slack environment 😆
Spiral is an equal-opportunity employer and we welcome applicants from all backgrounds. If you are game to come and help us make every company in the world customer-centric, then we’d love to hear from you!


It was a massive blow for the entertainment industry when one of the country's biggest festivals, Electric Picnic, announced it would not go ahead.
Despite multiple attempts to ask Laois County Council to reverse their decision against granting permission to organisers to host the festival, time had run out.
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In a statement, Electric Picnic told ticket holders that they had one of two options.
Understandably there are some ticket holders who will be seeking a refund, which Electric Picnic are happy to oblige to.
In their statement, those who had bought tickets were advised to contact Ticketmaster who will process the refund as soon as possible.
Those who want their ticket refunded have been told to contact Ticketmaster before September 30.
The other option is to hold on to their Electric Picnic ticket -- which will no doubt be like gold dust when the festival makes an epic return in 2022.
Organisers said: 'If you prefer, you can retain your ticket and carry it over to next year. If you choose this option instead of a refund, you do not need to do anything, just hold onto your ticket.'
The 2022 edition of the festival will take place on September 2 to September 4, 2022.
In a statement to social media on Wednesday evening, Electric Picnic 'regrettably' announced the 2021 festival has been cancelled.
The festival had been rescheduled to take place from September 24 to September 26 but Laois County Council refused to grant a licence for the festival.
The council has not taken any action and so the organisers have ‘run out of time’.
'We would not be able to do the festival justice this close to show day, and it would be unfair to ask ticket holders who’ve stood by us throughout this pandemic to come to EP and not get the full experience they are used to and deserve,' organisers said.


text:
Cyfres Amdani: Llythyr, Y
A book from the Amdani series, for Intermediate Level learners. In the small village of Treddafydd in the South Wales Valleys, Megan and Huw become lovers. But will their love be strong enough to survive the circumstances? Death, their families, and the years apart are all against them. Reprint. First published in 2018.

domain: library


Please read the new sticky announcement here for full details.
Discussion in 'Newbie' started by David Gilliland, Aug 24, 2017.
I looked at the club lathe this morning. It runs very quiet. It looks like the inboard bearing may be installed from the front and the rear one from the rear. Couldn't tell for sure if the hand wheel would tighten or loosen the fit of those bearings but you can loosen the setscrew and find out. Can't remember if the handwheel is left hand threaded or not however so that could be a little tricky. From your videos the noise definitely seems to be coming from the top spindle. As far as alignment goes did you clean out the morse tapers before inserting the drive and live centers. That can easily throw them off. The tailstock on the club lathe has very little slop but you should always push the tailstock toward the ways either front or back before locking it down. That or twisting the tailstock might bring things back into alignment. I don't know if small lathes are subject to this but larger lathes can actually twist the bed slightly if the legs are not level. Bolting it down to a board that isn't perfectly flat could feasilbly have the same effect of twisting the bed which would throw the tailstock out of alignment.
Well that's about all I can think of this morning.
Seeing is believing.......a new machine can have many problems.
Looks like QC is a thing of the past.
This is why many machines are taken apart and rebuilt after they arrive from offshore.
They are using poor quality bearings or were mishandled and destroyed during assembly.
Bearings being a precision component can be destroyed if not stored properly, and can also
be damaged during assembly if they are not assembled in a manner that is suitable for the
design of the bearing. The company I work for commission large numbers of rotating equipment
each year, many times we will dis-assemble a million dollar machine after it arrives from offshore to
validate and commission the equipment prior to running it. We have found on many occasions knock-off
bearings that are made by unknown sources, we will contact the bearing manufacturer and provide the
part number and serial number and many times they come back as being fakes. Documentation is many
times lacking on these machines as we archive and record dimensions and specifications and verify
components are made from specified materials. This allows us to order and stock repair parts for critical
equipment that needs to run and can be repaired on short notice. Bearings are one of the most common
"knock off" components in the industry.
If you return your old lathe to get a replacement, have them plug in the new lathe and run it at the store to verify you are getting a working unit.
This is another common problem that occurs with this lathe.
if the set screw loosens on the spindle pulley it will move along the shaft and ride against the spindle lock.
This will create a ticking noise on each revolution of the spindle much like a bad bearing.
Align the spindle pulley with the motor pulley so the belt runs true.
Use some loctite thread compound to secure the set screw from coming loose from vibration.
Another method is to use a second setscrew on top of the first. Be sure to make a note in your manual and a mental note about having double setscrews. Don't ask me why this is important.
Thanks so much for all your thoughtful replies. I decided to return the lathe with 1 day remaining in my amazon return window. They shipped a new one out immediately. It arrived days later with a massive hole through the box, likely from a forklift, that had completely sheared off the hand wheel in the back! So frustrating. I finally returned everything for a refund and found a local vendor who I bought it from.
As soon as I started up this new one it was clearly worlds better than any of the machines amazon had sent me. The tail stock and head stock are aligned perfectly, the vibrations are minimal and it's so much quieter. Don't think I'll ever make a large equipment purchase from amazon again. It feels like they sent me previously-returned equipment or equipment that was for some reason or another was second rate.
Just got a chuck and pen mandrel for my birthday so I'm pumped to start turning on this new and properly-functioning lathe!
Wonderful. It's always good to hear a happy ending. I always buy from trusted local dealers whenever I can. Even if the cost is a little more, after sales support is an important benefit.
for the alignment...have you tried adjusting the leveling feet? based on your picture, I would raise the back leg on the tail stock end a hair.
this will give a little twist and move your points into alignment.
Not sure how much if any that 1221 will twist. It's short and quite substantial. If I think about it I'll look at our club lathe tomorrow night and might see if it's possible to put a shim under one leg and see if it twists any.
I seriously doubt that there will be any noticeable twisting.
not sure about the 1221...but it works with the 1642
Long bed lathes can twist if the legs aren't level. the 1221 is a short bed lathe and is far stockier than most mini's which is why I thought it wouldn't work. Didn't have time to play with the lathe last night.


text:
On Tuesday, Cyprus, Luxembourg, Latvia and Sweden became the latest European nations to suspend its use, despite advice from the European Medical Authority (EMA) and other international medical agencies that the benefits of getting shots into arms outweigh any potential risks.
The head of the EMA, which authorized the use of the Oxford-AstraZeneca vaccine for the 27-nation bloc, said Tuesday that regulators remained "firmly convinced" of that assessment.
"At present there is no indication that vaccination has caused these conditions, they have not come up in the clinical trials and they are not listed as known or expected side events with this vaccine," its executive director Emer Cooke told a digital press conference Tuesday.
"We are still firmly convinced that the benefits of the AstraZeneca vaccine in preventing Covid-19, with its associated risk of hospitalization and death, outweigh these side effects," Cooke said, adding that she was concerned the suspensions would damage confidence in the vaccines.
|Read the full story:|


text:
Posted on 2017-8-19
- Kristina WNice selection. I keep shopping here because they stayed open the day before the hurricane in 2017. They filled my fridge when everyone else shut down. Good people. And excellent chicken teriyaki steam rolls.
- donald jGreat place and great prices. A very friendly and pleasant place to go and get questions answered on cooking authentic oriental cuisine. 2 thumbs up.
- Mohammed AGood stop shop for all Asian food and Groceries. Also very good sea food item.

domain: food


The scraping of skate blades on ice cuts through the stillness on a winter afternoon in Little Bay Islands, an island town 553 kilometres northwest of St. John's. It's because Mike Parsons and his wife, Georgina, have cleared a skating loop on the harbour.
While the 51-year-old Parsons grew up in this picturesque outport, he moved to Ontario to work in the software industry. But he and Georgina, 43, have moved back to retire here — at precisely the time that everyone else is getting set to leave.
That's because Little Bay Islands is the next community in Newfoundland and Labrador slated to close under a provincial government program designed to save money.
"Myself and Georgina, we wanted to become a part of the community while it still existed as a community," said Parsons. "We do all the stuff we love to do. We're outdoors people. We ski. We skate. We snowmobile."
"Money can't buy the happiness that this place brings us," said Georgina Parsons, who still works as a chartered accountant.
But the breathtaking beauty of their Little Bay Islands idyll may not be enough to save it. Under the provincial government's Community Relocation Policy, it would cost less to pay people to move to a larger town than to continue to maintain services such as electricity, garbage collection, road maintenance and ferry services.
Province expects savings
Little Bay Islands' only school has closed, the local fish plant has not operated for years and there are no medical services in town.
The provincial government said that a "rough cost-benefit analysis" projects a savings of $6,754,000 over 20 years if Little Bay Islands closes.
Two Newfoundland towns have been closed since 2002, and half a dozen more are at various stages of the process.
Under the program, residents receive between $250,000 and $270,000 to move to another town. But communities must volunteer to close and in a vote, at least 90 per cent of residents must be in favour of relocating.
A vote in Little Bay Islands came up just short of 90 per cent, but there's a strong likelihood they will reach that threshold in a subsequent vote.
The decision to leave has created a rift among a handful of residents. The Parsons are not eligible to vote and have decided to remain neutral.
"I totally get why people want to leave. I totally get why some people want to stay," said Mike Parsons.
Gord Weir, 81, a retired fisherman, said at one time, the town had a fishing industry, three sawmills and three dockyards, supporting a population of 500 people. But Weir said that for seniors or anyone with health issues, living on the island can be precarious.
"If you had a doctor's appointment, you might've been waiting three months to get one, and that very day that you're supposed to be to the hospital, the ferry's not running," Weir said. "But it's not going to be a great day when the time comes [for the town to be closed]."
The resettlement program has its critics, including Peter Fenwick, an innkeeper and the mayor of Cape St. George, on Newfoundland's Port-au-Port Peninsula.
"I think that the resettlement project is morally unjustified ... primarily because it targets rural Newfoundland to de-populate it," said Fenwick. He said that in many cases, the small, far-flung towns are major tourist attractions.
As housing becomes more expensive in cities such as Toronto, Vancouver and, to a certain extent, St. John's, Fenwick said small towns with good internet coverage can be attractive to some people looking to live off the beaten track.
Furthermore, Fenwick argues that the program is not as fiscally effective as it may seem, because it encourages residents in some communities that were likely to close anyway to hold out until they agree on resettlement and the payout to relocate.
"I would hope that the government would say, 'Our deficit is two billion dollars, we can't afford to do this anymore,'" said Fenwick.
Ferry too expensive
To further illustrate what he sees as misguided spending, Fenwick pointed out that the government shelled out $27.5 million to build a ferry, the Hazel McIsaac.
Launched in 2011, the Hazel McIsaac connects Little Bay Islands and nearby Long Island to the mainland, a half-hour ferry ride away, at an annual cost of nearly $4 million. The cost per resident per year for the ferry service is $16,455.
"Some bureaucrat or some politician has decided that we're going to have some big fancy boat," said Fenwick. "Other than the ferry service, living in rural communities is fairly inexpensive."
For some small communities, relocation may be inevitable, but one solution to closing down towns can be found in Centreville-Wareham-Trinity, population approximately 1,100, about a four-hour drive from St. John's.
Individually, these three communities may not have survived on their own, but in 1992 they amalgamated to form one municipality, which cut down on the cost of providing services.
Shane Noble, 40, owner of New Wood Manufacturing, grew up in Centreville. When he moved back to Newfoundland 15 years ago after a stint in Ontario, he said he convinced four families to return with him to work.
"I said, 'I've got an opportunity, can you come back?' And every one of them did," said Noble.
In the past two months, Noble has created a second company that will produce low-cost modular furniture. The co-founder of that venture is 25-year-old Alexa Perry, who recently moved back to the area after leaving as an infant with her parents when they lost their jobs after the cod collapse in 1992.
"If I told anybody that I was moving to Newfoundland to do marketing, they'd think I was insane, and it turns out there's plenty of opportunity to do marketing," said Perry.
She is happy she came back and plans to stay and reconnect with her roots. "I think there's an opportunity to cultivate creativity here," Perry said.
Indeed, the appeal of rural life is what drew Mike Parsons back to Little Bay Islands in its dying days. He is chronicling Little Bay Islands in photos for future generations.
"I'm trying to create or recreate some of that emotional connection to Little Bay Islands so that it doesn't get lost," he said.


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Rabid is one of David Cronenberg's first forays into the realm of body horror, and the film itself is about a woman who has a motorcycle accident, and decides to go through experimental surgery to help herself be able to return to normal life. However, this causes her to develop a stinger that feeds on human blood. Anyone she feeds on becomes infected with a very extreme form of rabies, which they can spread via biting other people.
The woman, who was played by a porn actress Marilyn Chambers, is very believable in her plight. She doesn't even understand what is happening to her or realize she is the source of the infection, even when the movie ends, she still doesn't believe. This movie isn't bad as his other movies as far as body horror goes, but you could say in this movie, there are definitely sexual connotations in the way the body horror is portrayed. I would say it is a low-key version of Shivers, which uses sex to spread infection via a parasitic organism. Both films are similar in using the mad scientist approach, except in Rabid, it's not clear if this was purposely or just an accidental mutation.
This movie ended up with a remake that was released in 2019, and it was a stinker. That one had Laura Vandervoort in the main role, which is she was good, but what they messed the formula which made the original film work so well. In the remake, it follows the whole experimental surgery causes an unexpected mutation, but instead, they make it clear it was a mad doctor who caused it. He wants to propagate the species of his creation, and why is that you ask? What could possibly motivate him to do this you ask? Because his wife had cancer. Yeah. The remake was pretty dumb if you ask me
Instead, being the purist I am, I recommend checking out the original. In fact, I would watch both Shivers and Rabid, it doesn't matter in what order, but I definitely feel the two are companion pieces
Till next time, stay safe and stay scared!! -Tha Thrilla-

domain: entertainment


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Current research in the Knight laboratory focuses on molecular interactions of proteins and lipid membranes, and on the development of single-molecule techniques for measuring them. Membrane-targeting proteins are normally soluble in the cytoplasm, but are recruited to membrane surfaces during cell signaling events. These proteins typically dock to the lipid membrane through one or more different types of molecular interactions, including (1) specific recognition of lipid headgroups as ligands; (2) nonspecific electrostatic interaction of positively charged regions of the protein with negatively charged lipids; (3) insertion of nonpolar amino acid sidechains into the hydrophobic interior of the membrane; and/or (4) interaction with other proteins on the membrane surface. We are particularly interested in discovering the molecular mechanisms of membrane interaction for proteins involved in insulin secretion. These interactions are expected to reveal important features of the proteins and membranes that enable proper regulation of secretion, and may offer clues to how secretion is dysregulated during progression of type II diabetes.
Biochemical and biophysical techniques are being used to investigate a number of individual membrane-targeting protein domains. These include a protein-to-membrane fluorescence resonance energy transfer method that can be used to measure both equilibria and kinetics of membrane binding. In addition, Dr. Knight’s recent and ongoing research has developed new applications of single-molecule fluorescence microscopy for measuring the kinetics and stoichiometry of protein-membrane binding.
Dr. Knight was introduced to the field of biophysical chemistry as an undergraduate chemistry major in the lab of Dorothy Erie. His undergraduate research involved RNA polymerases from thermophilic bacteria. Ph.D. research was completed in the lab of Prof. Andrew Miranker and focused on membrane interactions and amyloid aggregation of islet amyloid polypeptide (IAPP), a peptide secreted with insulin that forms insoluble aggregates in the diabetic pancreas. Dr. Knight continued to pursue interests in protein-membrane interaction through postdoctoral research in the laboratory of Prof. Joseph Falke at the University of Colorado at Boulder. There, his research developed methods using total internal reflection fluorescence microscopy to study these interactions at the single-molecule level.
Ph.D., Pharmacology, Yale University, 2006
B.S., Chemistry, University of North Carolina, 2000
Refereed research articles (supervised students italicized)
Vasquez, J.K., Chantranuvatana, K., Giardina, D.T., Coffman, M.C., and Knight, J.D. (2014) Lateral diffusion of proteins on supported lipid bilayers: Additive friction of synaptotagmin 7 C2A-C2B tandem domains. Biochemistry 53, 7904–7913. http://pubs.acs.org/doi/abs/10.1021/bi5012223
Lyakhova, T.A. and Knight, J.D. (2014) The C2 domains of granuphilin are high-affinity sensors for plasma membrane lipids. Chemistry and Physics of Lipids, 182, 29-37. Invited submission for special issue on phosphoinositides. http://www.sciencedirect.com/science/article/pii/S0009308413001370
Ziemba, B.P., Li, J., Landgraf, K.E., Knight, J.D., Voth, G.A., Falke, J.J. (2014) Single-molecule studies reveal a hidden key step in the activation mechanism of membrane-bound protein kinase C-α. Biochemistry 53, 1697-1713. http://pubs.acs.org/doi/abs/10.1021/bi4016082
Yamamoto, T.M., Cook, J.M., Kotter, C.V., Khat, T., Silva, K.D., Ferreyros, M., Holt, J.W., Knight, J.D., and Charlesworth, A. (2013) Zar1 represses translation in Xenopus oocytes and binds to the TCS in maternal mRNAs with different characteristics than Zar2. Biochimica et Biophysica Acta – Gene Regulatory Mechanisms, 1829, 1034-1046.
Brandt, D.S., Coffman, M., Falke, J.J., and Knight, J.D. (2012) Hydrophobic contributions to the membrane docking of synaptotagmin 7 C2A domain: Mechanistic contrast between isoforms 1 and 7. Biochemistry 51, 7654-64.
Ziemba, B.P., Knight, J.D., Falke, J.J. (2012) Assembly of Membrane-Bound Protein Complexes: Detection and Analysis by Single Molecule Diffusion. Biochemistry 51(8):1638-47.
Knight, J.D., Lerner, M.G., Marcano-Velázquez, J.G., Pastor, R.W., and Falke, J.J. (2010) Single molecule diffusion of membrane-bound proteins: Window into lipid contacts and bilayer dynamics. Biophysical Journal 99, 2879-87.
Knight, J.D. and Falke, J.J. (2009) Single-molecule fluorescence studies of a PH domain: new insights into the membrane docking reaction. Biophysical Journal 96, 566-82.
Knight, J.D., Williamson, J.A., and Miranker, A.D. (2008) Interaction of membrane-bound islet amyloid polypeptide with soluble and crystalline insulin. Protein Science 17, 1850-56.
Knight, J.D., Hebda, J.A., and Miranker, A.D. (2006) Conserved and cooperative assembly of membrane-bound a-helical states of islet amyloid polypeptide. Biochemistry 45, 9496-9508.
Knight, J.D. and Miranker, A.D. (2004) Phospholipid catalysis of diabetic amyloid assembly. Journal of Molecular Biology 341, 1175-1187.
Knight, J.D. and Adami, R.C. (2003) Stabilization of DNA utilizing divalent cations and alcohol. International Journal of Pharmaceutics 264,15-24.
Eakin, C.M., Knight, J.D., Morgan, C.J., Gelfand, M.A., Miranker, A.D. (2002) Formation of a copper specific binding site in non-native states of b-2-microglobulin. Biochemistry 41, 10646-56.
Biochemistry (CHEM 3810)
Biochemistry Laboratory (CHEM 4828)
General Biochemistry I (CHEM 4810/5810)
General Biochemistry II (CHEM 4820/5820)
Physical Biochemistry Laboratory (CHEM 4518)

domain: chemistry


text: Budget Villas In Jaipur Near Ajmer Road, including a yard, shared lounge as well as sights of city, CK Villa is set in Jaipur, 1.3 kilometres from Sindhi Camp. Among the facilities of this property are an eating facility, a 24-hour front workdesk and room remedy, along with absolutely cost-free WiFi. The Budget Villas In Jaipur provides an attendant solution, ticket remedy as well as currency exchange for visitors. Rajasthan, a land of heroic warriors, legendary kings, gorgeous maidens in addition to abundant customizeds has actually always been popular for its motivating folktales. come and also stick to us in our comprehensive home to strike right into a tale, share the sunlight, smell the fresh sand and likewise to obtain some vibrant colours for your memory lane at Budget Villas In Jaipur.


Don’t judge a book by its cover they say, but what about a brand by its slogan?
If you have already tried a product and liked it, there is a high chance of you buying it again. But when you visit a supermarket or online store and find yourself swimming in a sea of unknown products, how do you choose? Brand slogans are designed to make consumers remember a brand when making a purchase decision. It might not be the most objective and informed decision, but when there is nothing to use as a point of reference, a funny song could do the trick. Talking about being objective, you would think a marketing campaign has honest information to help you understand what the product is all about. However, sometimes the whole point of a branding strategy is to show what the brand wants to be all about, rather than what they really are. What they want consumers to perceive them as and be happy to pay for. It doesn't mean that all campaigns are tricky or dishonest, sometimes it’s just a matter of not knowing their own target market. But honesty is growing more important to consumers. Consistency is very important for an honest marketing campaign. Providing consumers with an approximate experience to the one they had envisioned guarantees repeat purchases. Also, it gives your brand credibility in the customer’s eyes. Once a consumer has felt disappointed or mislead by any product, they will probably feel hesitant to purchase other lines of products from the same brand. As a fun exercise, we went on HonestSlogans.com and found a few entertaining examples of what an honest slogan would do to a brand. Let’s see if you would be eager to purchase any of these:
A more honest explanation of this particular magazine’s content.
Not quite the corn flakes but there is a Kellogg’s product for every taste
Not the busiest of social networks
They said it, we just liked it and share it
The eternal battle of the bubbly colas
What a reputation
Do you want fries with that? None of these slogans is likely to go out to the public, but it is a fun way to show what the brand perception would do for this group of brands. Remember these examples next time you plan your label printing. You should stand for what you advertise, avoid misleading slogans to gain happier customers. We want to know what you think. Which honest slogans will you add to a popular product? Go to our comment section and let us know!


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Cherish traded one heavy hitter for another in the remix to Killa, replacing Yung Joc with veteran Jermaine Dupri and So So Def newcomer The Kid Slim. Slim gives an entertaining verse toward the end, but Dupri, who does more singing than rapping, only makes an appearance at the beginning of the song (unless you count the four words at the end). We’ll allow him to slide since he’s the mastermind behind the remix. The new beat has more of a Lil Jon feel than the semi-techno sound of the original, but the lyrics in the verses, chorus and bridge are all maintained. Cherish will release their new album, The Truth, on April 29.
Written by Angela on 04/9/08
First DJ Booth Appearance:
"Magic City ft. Cherish" (2007)
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Our boys in Smile, Look Alive will be performing this Saturday 11th Feb with the bands Decade and Sell Your Sky at the Thekla in Bristol. Come along and give some love!
The Thekla Top Deck
The Grove, Bristol
Tickets £6 Advance
Another class act we’ve come across in our local area, Smile, Look Alive are a professional and talented 5 piece from Bristol.
This Pop-Punk outfit hailing from the Bath/Bristol area. They have just finished their debut record with Ben Humphreys and John Mitchell (YM@6, Enter Shikari, Kids in Glass Houses, The Blackout, etc.) and are looking to set the UK music scene alight with their brand of catchy Pop-Punk. They have only been around a matter of months but 2011 is looking to be a big year for this promising young band!


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MANC CAT with BATS Halloween Special
£12.50 / On Sale
If a Manx cat has no tail a Manc cat must have a buzzing stripey one... this edition features 3 bats. It was released fir Halloween 2018.
This 2 layer screenprint is on white card and signed by Mancsy.
It will be live in the shop in November 2018.
- 13 13 in stock

domain: hobby


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There are times when it’s OK, even cool, to look the part of a professional photographer, but other times, keeping a low profile is a much smarter course of action. Let’s face it, an obvious camera bag can make you a target for a soft or hard theft, and nothing ruins a vacation or business trip like losing all your gear.
That’s the thinking behind the Think Tank Urban Disguise series of camera bags. This scaled line starts small and finishes quite large, all in a subtle, non-overtly camera-bag styling. At a glance, the bags look just like ballistic nylon briefcases and laptop bags, but, really, they’re built to haul camera gear.
If you own or have used this bag, let us know what you think! Leave your comments and thoughts below.
Get information and user reviews for this bag from Amazon: Think Tank Urban Disguise 50, Plain Looking, Fully Functional Briefcase Size Shoulder Bag for Two Pro SLRs, Multiple Lenses & 15


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Please review the FAQs and contact us if you find a problem. Credits: 1 Recommended: 9th Test Prep: AP World History This is a broad, survey course; you will need to do additional study to take these exams: Western Civilization I, Western Civilization II ( Each is.


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by Sally McBride
August 1, 2013
Marrula Tamara, once Empress of Worlds, has been exiled for treachery to a planet called Strand. She has one great treasure: the engineered horse Raj’azul. In his blood lies the secret of her immortality…and the seed of her downfall.
As her fellow exiles form a primitive society, centuries pass while Marrula schemes revenge. She needs three things: Raj’azul’s blood, the time-twisting mind of her own great-granddaughter, and the utter ruthlessness to use them both. But when her rebellious slave Warrek realizes Marrula is about to destroy a world to save herself, he steals the horse and vanishes into the wild mountain territories. He must remain free long enough to kill the innocent girl and thwart Marrula’s plan.
But in remote Tarlannat Hold he finds a woman even more beautiful and ruthless than Marrula…the doomed girl’s mother, Kael. And Kael knows what is at stake.
If these three women’s rogue Talents meld, time itself will be unwound and the universe destroyed. Warrek must join forces with the one man who truly despises him and battle his way to the center of the coming time storm. Together, these two pawns might succeed in toppling a Queen….
Fascinating world…. Complex characters who are not always likeable.