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Imagine a world full of happy smiling people! This is what dentists around the world at Hemet TMJ and the Hemet Sleep Therapy Center are working on. Their dental services range from cleaning to full mouth remodeling. Specialists at Hemet TMJ and Sleep Therapy will examine your mouth, tell you about your weaknesses and provide treatment. If necessary, your doctor can provide you with surgical intervention. The price of services at this clinic depends on:
- initial health of buccal cavity
- specifics of toothache
Whether you need extensive oral health dental services or just cosmetic dentistry, Hemet’s specialist TMJ and Sleep Therapy Centers are here for you. A rating of 4.8 shows that users love this place! You can read the reviews to find out the positive and negative moments people mentioned when visiting Hemet TMJ and Sleep Therapy Center.
To learn more about this place, you can visit www.hemetcaltmjandsleep.com. For more information or to make an appointment with a professional, you can call +1 (951) 331-32-37 or visit the company directly at 550 E Latham Ave Suite 3, Hemet, CA 92543.
I am very pleased with my experience at Dr. Jergensen’s office. It started with his friendly and knowledgeable staff. He even has ceiling mounted video screens for patients to watch movies during dental procedures. Dr. Jergensen prescribed the exact treatment to give me the desired results. He did not try to convince me to do things that were not necessary. The most important thing to me about Dr. Jergensen is his passion for Dentistry. He is a perfectionist who puts in the time and effort to ensure outstanding treatment results. The transformation of my teeth from how they were before we started to now is remarkable. He takes great pride in his work and has the skills necessary for an outstanding treatment result. I highly recommend Dr. Jergensen for complex Dental Procedure needs.
Dr J and the staff are great. Dr.’s attention and dedication. J. Details are second to none. He is also very funny! ! He saved my tooth today, we thought it couldn’t be saved because the crack was so deep, but he persevered, found the end of the crack and was able to save it. I have full confidence in my excellent dentist and my wallet intact. Thank you, Dr. J., for your commitment to provide us with the best possible care! you are great.
Dr. Jergensen is so kind, thoughtful and attentive to the details, which is exactly what you want (and need) in a dentist. He genuinely cares for his patients and wants to help them get the best care and results possible. I especially appreciate that he brings a comprehensive approach to his patient care. I highly recommend Dr. Jergensen!
Hemet TMJ and Sleep Therapy Center FAQs
📍 What is the official address of Hemet’s Temporomandibular Joint and Sleep Therapy Centre?
This place is located at the following address: USA, Hemet, CA 92543, 550 E Latham Ave Suite 3.
☎ What is the phone number for Hemet TMJ and Sleep Therapy Center?
You can try calling the following numbers: +1 (951) 331-32-37.
🕖 What is the working schedule of Hemet TMJ and Sleep Therapy Center?
The Hemet TMJ and Sleep Therapy Center is open as follows: Monday-Thursday: 8am-5pm.
⭐ What is the user rating for Hemet TMJ and Sleep Therapy Centre on Nicelocal.com?
The average rating for this place is 4.8 out of 5. You can visit the Hemet TMJ and Sleep Therapy Center Reviews section to read what others have to say about this place or compile your own feedback!
🧾 Is there a price list on Nicelocal.com for the goods and services offered by TMJ and Hemet’s sleep therapy centers? Yes! You can find it in Hemet’s TMJ and Sleep Therapy Center price range.
🏥 What kind of medical institution can Hemet TMJ and Sleep Therapy Center be called?
The Temporomandibular Joint and Sleep Treatment Centre in Hemet can be thought of as a dental clinic.
🦷 Does Hemet’s TMJ and Sleep Therapy Center provide services related to dental and oral health?
At Hemet’s TMJ and Sleep Therapy Center, they offer Endodontics and Basic Dentistry.
✔ Is the information on this page reliable?
Nicelocal does its best to include reliable data about institutions in its directory. If you find inaccuracies or if you are an official representative of Hemet TMJ and Sleep Therapy Center, please feel free to let us know using the feedback form.

domain: medical


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Madison Memorial senior Kole Kerkhoff announced Wednesday on Twitter that he plans to attend Western Technical College and compete in baseball.
Kerkhoff was an honorable-mention all-conference selection as a pitcher in the Big Eight in 2019. The spring sports season wasn’t played this year due to the COVID-19 pandemic.
The 6-foot-1, 160-pound Kerkhoff was a second-team all-conference pick as a kicker in football this past fall when Madison Memorial was the league champion.
Western Technical College is in La Crosse. The Cavaliers play in the Minnesota College Athletic Conference and compete in baseball, men’s and women’s basketball and volleyball.
Kerkhoff tweeted: “I’m proud to announce that I will be continuing my academic and athletic career at Western Technical College. Thank you to Coach Knoll for this opportunity!”
Western Technical College’s 2020 baseball season was canceled due to the coronavirus outbreak.
Josh Knoll is the head coach. The Cavaliers’ home games are played at Copeland Park in La Crosse.
Western Technical College defeated Northland Community & Technical College 69-60 in the 2019-20 NJCAA Division III women’s basketball national championship game in March in Rockford, Ill. It was the first national title in any sport for Western Technical College.
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domain: sports


Combined Cycle Systems for Near-Zero Emission Power Generation - Woodhead Publishing Series in Energy (Hardback)Ashok D. Rao (editor)
Hardback 360 Pages / Published: 12/04/2012
- We can order this
Combined cycle power plants are one of the most promising ways of improving fossil-fuel and biomass energy production. The combination of a gas and steam turbine working in tandem to produce power makes this type of plant highly efficient and allows for CO2 capture and sequestration before combustion. This book provides a comprehensive review of the design, engineering and operational issues of a range of advanced combined cycle plants. After introductory chapters on basic combined cycle power plant and advanced gas turbine design, the book reviews the main types of combined cycle system. Chapters discuss the technology, efficiency and emissions performance of natural gas-fired combined cycle (NGCC) and integrated gasification combined cycle (IGCC) as well as novel humid air cycle, oxy-combustion turbine cycle systems. The book also reviews pressurised fluidized bed combustion (PFBC), externally fired combined cycle (EFCC), hybrid fuel cell turbine (FC/GT), combined cycle and integrated solar combined cycle (ISCC) systems. The final chapter reviews techno-economic analysis of combined cycle systems. With its distinguished editor and international team of contributors, Combined cycle systems for near-zero emission power generation is a standard reference for both industry practitioners and academic researchers seeking to improve the efficiency and environmental impact of power plants.
Publisher: Elsevier Science & Technology
Number of pages: 360
Weight: 690 g
Dimensions: 234 x 156 x 25 mm
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The Office of the United Nations High Commissioner for Refugees was established on December 14, 1950 by the United Nations General Assembly. The agency is mandated to lead and co-ordinate international action to protect refugees and resolve refugee problems worldwide. Its primary purpose is to safeguard the rights and well-being of refugees. It strives to ensure that everyone can exercise the right to seek asylum and find safe refuge in another State, with the option to return home voluntarily, integrate locally or to resettle in a third country. It also has a mandate to help stateless people. Since 1950, the agency has helped tens of millions of people restart their lives. Today, a staff of more than 9,300 people in 123 countries continues to help and protect millions of refugees, returnees, internally displaced and stateless people.


Not too short, not too long -- these stretch skimmers satisfy many spring and summer styles. From Denim & Co.® Fashions.
- Fabrication: Duo Stretch
- Features: self-folded waistband with front encased flat elastic and inside back with two rows top stitching and straddle stitch at seam
- Rise: slightly below the waist
- Fit: fitted; cut to follow the lines of the body
- Leg Shape: straight leg
- Inseam: missy/plus inseam 17"
- Content: 90% cotton/10% spandex
- Care: machine wash, tumble dry
To see the specific garment measurements for this item,
Tune in to QVC for Denim & Co.(R)
Saturday, June 3, 2023 from 7 – 10 a.m. ET
and Monday, June 5, 2023 from 4 – 5 p.m. ET
and Thursday, June 8, 2023 from 1 – 2 a.m. ET
and Saturday, June 10, 2023 from 7 – 10 a.m. ET


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As a creative child who has always enjoyed performing, storytelling, and engaging audiences, Ashley knew journalism was the path for her.
After graduating from the University of Western Ontario with a Master of Arts in Journalism Degree, Ashley began her career in her hometown at Global News in Toronto. While at Global Toronto Ashley worked as an editorial assistant, producer on The Morning Show, and as a field/chase producer collecting stories on Canadian athletes heading to the Sochi 2014 Winter Olympics.
Happy to grow her career, this time in front of the camera with Global, Ashley joined Global Winnipeg as a Reporter/Anchor.
When she’s not reporting, Ashley enjoys checking out her new city and meeting the fascinating people that call Winnipeg home. She also enjoys going on travel adventures, and most of all playing with her sassy Siamese kitten.

domain: artistic


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I was pleased with yesterday's shot, but I much prefer this one, mostly because of the sky – it has that beautifully surreal feel that you only get with long exposures at night.
As for processing: I've used a different white balance setting for this shot (as opposed to yesterday's) and the only other adjustment was a very slight bump in contrast. The deep saturation is entirely 'natural'.
9.23pm on 26/11/04|
EF 17-40 f/4L USM
17mm (27mm equiv.)


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I used to love going to the Keg back in the day when there was a big salad bar and the steak and lobster were served on wooden boards. I went back recently with a friend and was disappointed to find that the prices are now over the top and the food was no better, in fact not as good. Won't be back.
Own or manage this property? Claim your listing for free to respond to reviews, update your profile and much more.

domain: food


This paper is concerned with the problem of detecting and isolating multiple faults by a full-order observer of the plant state. We first obtain the fault isolability condition from the dual concept, namely static-state feedback decoupling. A new full-state observer design method is then developed to isolate simultaneous multiple faults. The method can isolate m simultaneous faults with m output measurements (such that the isolability condition is satisfied) under zero initial error of state estimation. Asymptotic fault isolation results can also be obtained using the same observer design if the number of invariant eigenvalues is (n - m), and if they are stable, where n represents the system order, m is the number of faults in the system. In both cases m can be up to the system order n.
- Fault detection and isolation
- Full order observer
- State feedback decoupling
ASJC Scopus subject areas
- Control and Systems Engineering
- Computer Science Applications
- Electrical and Electronic Engineering


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Introduction to Manx PoliticsDemocracy is at the very heart of the Isle of Man Government. Everyone has the same rights and the same opportunity to be heard.
The Isle of Man has its own political system and parliament, Tynwald. This allows the Island to have political autonomy from the UK and control over domestic legislation with the only areas outside of its responsibility being immigration and defence.
Democracy is at the very heart of the Isle of Man Government. Everyone has the same rights and the same opportunity to be heard. We even have a day every year (Tynwald Day) when any Isle of Man resident can directly petition parliament with any issues or grievances they may have.
General elections are held every 5 years, with the next one taking place in 2021. Anyone aged 16 or over can vote in general elections.
Tynwald holds debates on key Isle of Man issues and passes laws. It consists of two branches: the House of Keys and an upper chamber, the Legislative Council.
The Queen is Lord of Mann and is the Isle of Man's Head of State. She is represented on the Isle of Man by the Lieutenant Governor.
House of Keys
The Members of the House of Keys (MHKs) are elected every five years. Political parties play a very small role in Isle of Man politics, with the vast majority of MHKs elected as independents.
Members of the Legislative Council are elected by Members of the House of Keys.
The Chief Minister
The Chief Minister is the executive head of the Isle of Man Government . They are voted for by fellow members of the House of Keys following a General Election.
The two branches have joint sittings once every month between October and July. Each year on the 5th July (if this falls on a weekend, the date will be the following Monday) Tynwald meets outdoors in St John's, a village in the west of the Island. This is a Bank Holiday on the Isle of Man and any citizen can raise a petition to the members of Tynwald for debate.
The Isle of Man has its own national anthem that is often performed alongside the British National Anthem.
O Land of Our Birth (First Verse)
O land of our birth
O gem of God's earth,
O Island so strong and so fair,
Built firm as Barrule,
Thy Throne of Home Rule
Makes us free as thy sweet mountain air.

domain: law


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Today, I am so excited to share this beautiful retro inspired Vancouver wedding photoshoot. This couple have keep Game of thrones inspired theme.
Look at the very classy,elegant and retro table decorations.
Please find your name here in table of thrones…
Retro chair designs
Love this decoration
Gorgeous retro-styled decor
ohhh my my….lovely retro veil…<3
Photographer: Thomas Bullock Photo
Florals: Olfco Co
Dress: JJ’s House
Makeup: Paige Griffith Makeup
Food: Buena Ondayvr

domain: design


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Lyle Foster and Luther Singh, together with Kaizer Chiefs’ centre-back Siyabonga Ngezana, arrived on Monday morning to form part of South Africa’s squad that is in camp for this year’s Under-23 Africa Cup of Nations (Afcon).
The trio said they are looking forward to contributing to SA’s ambitions of qualifying for next year’s Tokyo Summer Olympic Games.
In order to achieve that goal, South Africa will need to secure a top-three finish in the tournament.
The national juniors kicked off their Under-23 Afcon campaign with a 0-0 draw against Zambia in their opening Group B match, played over the weekend.
They will now face Ivory Coast in their second group tie at the Al Salam Stadium on Tuesday.
Coach David Notoane said he and his technical staff will plan accordingly for their second group tie against the West African side.
“We are happy to have Lyle Foster, Siyabonga Ngezana and Luther Singh who reported for camp today,” Notoane said. “This now puts us to a total of 20 players in camp leading up to our second group match against Ivory Coast. We are expecting Keanu Cupido to join the team sometime this week.
“Having these numbers in the camp gives us a nice headache going into our second group match,” Notoane added. “We will prepare accordingly and push for a winning result in that tie.”
In partnership with ANA and Sports Leo

domain: news


FREE image of KSC-04pd1567
KENNEDY SPACE CENTER, FLA. - On Launch Pad 17-B at Cape Canaveral Air Force Station, the MESSENGER (Mercury Surface, Space Environment, Geochemistry and Ranging) spacecraft is seen atop the Delta II upper stage booster (middle) and the Delta II launch vehicle below. The spacecraft is ready for installation of the fairing, a molded structure that fits flush with the outside surface of the upper stage booster and forms an aerodynamically smooth joint, protecting the spacecraft during launch. Seen on the right is one of the solar panels on the spacecraft. On the left is the heat-resistant, ceramic-cloth sunshade that will protect the spacecraft’s instruments as MESSENGER orbits the Mercury where the surface reaches a high temperature near 840 degrees Fahrenheit and the solar intensity can be 11 times greater than on Earth. MESSENGER is scheduled to launch Aug. 2 and is expected to enter Mercury orbit in March 2011. MESSENGER was built for NASA by the Johns Hopkins University Applied Physics Laboratory in Laurel, Md.
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Description: The Professional Master Degree in Marine Conservation provides students with advanced training in both the theoretical aspects of marine science and conservation, as well as the practical aspects required to begin a career in this field. This degree track is unique in that students design a curriculum that emphasizes their personal goals and interests, while focusing on innovative solutions to current marine ecosystem and organism threats. The goal of the track is to advance conservation efforts, scientific literacy and communication, public outreach and integration, and education within the marine realm. Practical aspects of the program will vary between individuals but may include exposure to field methods and techniques, GIS and remote sensing of shallow water marine environments, the development of environmental impact statements, coastal law, the development of social media, scientific communication, and statistics for environmental management.
Miami, Florida, United States
University of Miami


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DAY 01 - Arrival to Istanbul:
Upon arrival in Istanbul (Istanbul Airport), our representative will meet you & transfer to the hotel.
(Check-In after 13:00pm) and check in to hotel. Rest of day is leisure and Overnight in Istanbul.
DAY 02 - Guided Istanbul Tour:
Breakfast, visit to the ancient Byzantine Hippodrome where you will tour the Egyptian Obelisk, Serpentine Column, Fountain of Wilhelm II, the elegant Blue Mosque famous with its heavenly six minarets and the Hagia Sophia Museum, built during the reign of Emperor Theodosius and burned down in the fire of Nika Revolt in 532 A.D. After lunch visit the Topkapi Palace (excluding harem), residence and administrative center of the Ottoman Sultans. Overnight in Istanbul.
DAY 04 - Bosphorus Cruise / Fly to Izmir (Meals: Breakfast)
Breakfast, 08:20am short drive to Spice Market, Egyptian Bazaar heaped with various sweets & spices is one of the world’s largest spice bazaars since 1665. Then embark on the Bosphorus ferry for an unforgettable cruise along the Bosphorus, the beautiful strait that divides Europe from Asia. 14:00pm transfer to airport for an afternoon flight to Izmir at 17:00 pm. 18:00pm, Arrival to Izmir, meet and transfer to hotel Kusadasi. Overnight in Kusadasi
DAY 04 - House of Virgin Mary and Ephesus:
Breakfast, todays sightseeing tour will take you to visit the remains of Artemis Temple, one of the 7 Wonders of the Ancient World. Then on to visit Ephesus Ancient City, the best preserved Greco-Roman city in the world. After a lunch break depart for the House of Virgin Mary and visit the chapel where she is said to have spent her last days. Overnight in Kusadasi.
DAY 05 - Pamukkale to Fethiye:
Breakfast, and meet with the guide to depart for Pamukkale where you will have the chance to visit the natural travertens formed by lime deposits along with ruins of Hierapolis. At end of the tour day you will be transferred on to the bus station in Pamukkale for departure by intercity bus to Fethiye, arrival early evening with transfer to hotel. Overnight in Fethiye.
DAY 06 - Oludeniz & Fethiye:
Today is free at leisure for you to relax on the beach in Oludeniz or explore parts of this resort town and the old Greek Village to Karakoy. Overnight in Fethiye.
DAY 07 - Fethiye to Antalya:
Breakfast, check out and transfer to the bus station for a daytime intercity bus to Antalya. On arrival in Antalya meet for transfer to hotel and remainder of day at leisure. Overnight in Antalya.
DAY 08 - Sightseeing Tours in Antalya:
Today you have the chance to explore Perge, an important city of ancient Pamphylia and the Aspendos Theatre one of the best preserved theatres in the world with seating for 15,000. Still used today, the theater alleries, stage decorations and acoustics all testify to the architects success. The days tour includes a visit to Kursunlu Waterfalls. Overnight in Antalya.
DAY 09 - Antalya to Cappadocia:
Breakfast, check out and day at leisure to spend relaxing on the seaside or doing some further sightseeing on your own before transfer to the bus station for travel by overnight intercity bus to Cappadocia.
(Note: If you prefer to fly, flights would go via Istanbul)
DAY 10 : Arrival & Cappadocia Tour including Goreme (Meals: Breakfast+Lunch)
07:00 am Arrival Cappadocia, meet and transfer to hotel. 09:45 am, visit Goreme Open Air Museum consisting of five Byzantine Orthodox churches. Visit also Uchisar to take pictures of "The Castle" and sightseeing. Lunch in Goreme and then visit Avanos which is famous for its potteries. You can see their demonstration and you can try to make it. After that a visit to the valley of fairy chimney, the name is Pasabagi then we continue to see Cavusin (Rose Valley) which has amazing beautiful red rock formations. Next is the Devrent Valley and Urgup afterwards. Following that a panoramic view point to observe the fairy chimneys. Overnight in Cappadocia.
DAY 11 : Cappadocia Tour /Flight to Istanbul (Meals:Breakfast+Lunch)
(OPTINAL:This morning an hour hot-air balloon ride available with extra cost of 180.00 EUR Per person)
Breakfast, 09:45am, depart to visit Ortahisar we can have good photo opportunity of Ortahisar rock castle. Mustafapasa which was old Greek Village once called Sinasos. There are old Greek churches in this town. After that we drive through Sahinefendi and then visit a roman ruins of Sobesos which is recently excavated that has very nice ground mosaics. Soganli Valley We walk 2 km in the valley and visit famous cave churches. Lunch in Soganli Village then Kaymakli Underground City that is the deepest underground city. Transfer to Kayseri airport for flight to Istanbul at 19:30pm.
21:00pm arrival to Istanbul, meet at the airport and transfer to your hotel. Overnight in Istanbul.
DAY 12 - Departure:
Breakfast, check out and as per your flight time transfer to Istanbul International Airport.

domain: geography


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On Dec. 9, it became legal for same-sex couples to wed in Washington State. Seattle Channel Producer Jeff Gentes takes a look at this historic event. From the lines around the courthouse to get a marriage license, to the 138 couples who tied the knot at a big City Hall bash, the Seattle Channel looks at what this new law means to all residents of Washington State.
It’s been a few days since the last couple left the marriage celebrations on City Hall and we’ve been working to compile and post photographs, video and news stories, which just keep coming. Explore some of the amazing pictures and videos that were taken during the event or read the news and media page, where we’ve collected stories, photos and observations of the event from twitter, blogs, and the web.
For couples, families friends and supporters who attended, please feel free to share links to your own galleries in the comments.
Our public Flickr pool – Crowdsourced photographic highlights of the event
Couple cam videos – Wedding day messages to friends and family, and reflections on the historic day
News & Media
We’ve collected some of the reaction to Sunday’s incredible event.
As part of its day-long coverage of yesterday’s historic weddings at City Hall, the Seattle Channel made an area available in the reception room for newly married couples to tell their stories and deliver live messages to loved ones who couldn’t make the trip to Seattle. All day, couples sat down in front of the cameras to share their feelings and thoughts on the historic occasion of their own weddings, and what those weddings mean to our society.
34 of those videos can be viewed at a website the Channel has set up.
“Gracias Seattle; Gracias a todos.”
“I hope some of the folks in Pullman are watching.”
“Hi Mom and Dad!”
“We came up from Portland to get married in Seattle: here we are! When we’ve overturned DOMA, that’s the end of our journey.”
One hundred and forty weddings are scheduled to take place this Sunday at City Hall. Come join the celebration at City Hall Plaza from 10 AM to 5 PM, on Fourth Avenue downtown between James and Cherry streets.
Congratulate and admire the newlyweds coming down the steps from City Hall and enjoy food trucks, coffee and festivities. Don’t miss this historic day in Seattle!
Please note: In order to be married at Seattle City Hall on December 9th, couples must get a marriage license on Dec. 6th and MUST have RSVPd on our website while registration was still open. Unfortunately we have had to close RSVPs. We are limited by space in City Hall, so we are only able to serve 140 couples. Our original plan would have accommodated only 80, but when we saw the demand, we were able to find room for more wedding locations in City Hall and increase to 140.


Samsung Galaxy Note long had identity issues. It is a device which can be used as a Tablet or a phone. Best of both worlds perhaps ? As it might appear this device has ability to produce gorgeous visuals thanks to its Duper AMOLED HD screen with 1280 x 800 resolution.
RocketROM takes the beauty to the next level. The colors are amazing and so are the other features which includes Sony Bravia Engine as well as the FM Kernel which will help you get even more out of the large 2500mAh battery.
- Fixed Baseband Issues (no more workaround flashing v1 necessary!)
- Deleted Call Rec Mod causing baseband issues –> flash seperatly but be aware of losing baseband when doing Full Wipe!
- GPS Signal / GPS Fix show up correctly now
- No more loss of USB connection in charging mode when screen off
- Automatic zipalign of all system apps on every reboot (was build in before, but I forgot to mention)
- Some minor optimizations in scripts and tweaks
- New bootanimation (the old one was to special for most of u )
- Still FM Kernel v1.4 –> flash any other Kernel, but look for init.d-support (Abyss has, but none of chainfires!)
Download the ROM from here.
Place it on your SD card.
Reboot to recovery/CM Recovery.
Select Install from ZIP.
Select the file.


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‘Playboy Redux II’ opens this Sat, Dec. 18th at the Copro Gallery over in Bergamot Station in Santa Monica. The show features a stellar lineup featuring a few Thinkspace family regulars (including the above and below gems from Brian M. Viveros and David MacDowell). The show will feature a number of works that showed at the Warhol Museum’s presentation of this exhibition earlier this year along with a group of new reinterpretations of the iconic bunny. Come help celebrate 50 years of Playboy this Saturday.
Gary Baseman, Frank Kozik, Luke Chueh, Glenn Barr, SHAG, Brian M. Viveros, Tara McPherson, Dan Quintana, Stanley Mouse, Mark Bodnar, Leslie Ditto, Bob Doucette, Lang Leav, Vincent Cacciotti, Nouar, Tin, Keith Weesner, Lisa Petrucci, Ausgang, Bob Masse, David MacDowell, Isabel Samaras, Juan Muniz, William Wray, Marco Almera, Saya Woolfalk, R. Black, Jeremy Tinder, Daniel Elson, Scott Anderson, Jennnybird Alcantara, Brian Ewing, Jeremiah Ketner, Steve Seeley, Bonni Reid, Ken Keirns, Hiroki Otsuka, Andrew Schoultz, Ain Cocke, Shaunna Peterson Travis Lampe, Michelle Valigura, & many more
Sat, Dec. 18th 8-11:30PM
2525 Michigan Ave, Space T-5 at Bergamot Station in Santa Monica / 310.398.2643
‘Playboy Redux II’ featuring contemporary artists interpreting the iconic Playboy Bunny + a small showing of new works from KuKula in gallery 2
(On view through Jan. 6th)


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The Cheatham County School District is hosting a Job Fair on Thursday, March 10.
The district is starting to fill positions for the 2022-2023 school year, and the Job Fair is a great opportunity to learn about these available positions.
The district is hiring certified teachers in all subject areas and grade levels and classified positions in the School Nutrition, Daycare and Transportation departments.
“We encourage anyone who would like to learn more about our employment opportunities to attend,” said Wendy Cox, the district’s Human Resources Supervisor. “We will have representatives from all schools and departments in attendance, and they will be available to answer questions and talk with candidates.”
Those who attend are asked to bring an updated resume.
The Job Fair will be held from 2-5 p.m. at the Cheatham County Transportation Facility, 4021 Sweethome Road in Ashland City.
For a list of available positions, visit www.cheathamcountyschools.net and look under “Employment.”
For more information, contact Cox at [email protected] or call the Board of Education office at 615-792-5664.


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The best treatment
- Massage for pregnant women
- Sport massage
- Visceral osteopathy
- Pediatric osteopathy
- Somato emotional osteopathy
- Functional osteopathy
- Australian bush Flower systeem
They are therapeutic massages in which we work the body manually with different techniques and positions but we also use other techniques such as suction cups, cryotherapy and kineotapping.
What we try with this type of therapy is to relax the bodytissue and release different tensions that may have been developed.
Massage for pregnant women
Osteopathy for pregnant women
It is a treatment that evaluates the different structures or tissues of the viscera. It is also normally connected to structural problems and with this reason the osteopath always evaluates both things at the same time. When pathologies exist at the visceral level it is because their original movement is altered and can affect other structures such as the diaphragm, etc.
They are very soft and subtle techniques that are used to correct alterations in our body originated from birth or fetal state.
The following pathologies are treated: </ strong>
- Nighttime disturbances
- Infantile colic
- Difficulties in learning
It is a treatment of body and mind in which we work in releasing some negative traumas in doing so, which loosens and improves the physical state of the person. The person can frequently manifest different emotions such as fear, anguish, joy, etc.
It can also be called structural osteopathy. It is the one that studies how the body is at a biomechanical level and if there is any type of alteration at the musculoskeletal level, manual techniques of different types are applied to rebalance these dysfunctions.


text:
Send this profile to a friend
Constangy Brooks & Smith LLP
News from The Business Journals
Apr 18, 2014, 6:00 am EDT
A new Hotel Indigo is coming to one of downtown Atlanta’s first office buildings developed by renowned architect John Portman.
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Being a manager is never easy. Being a new manager is even more difficult.
Jul 8, 2011, 6:00 am EDT
This week’s question:
Jan 21, 2011, 6:00 am EST
The Patient Protection and Affordable Care Act was passed to help small businesses, but one business owner called it “the most punitive legislation” t ...


i want to make a bag to carry stuff inthe last one i made stretched i made it out of cottoni crochet it with a small hook and only used scit stretched out hugelyi washed and dried it twicedidnt helpcan i use ordinary string i would use 2 strands at onceis it possiblethanks sylvia:think:
You can buy what's called kitchen cotton which is much thicker, like yarn, and you'd use a large crochet hook. Look for Sugar and Cream, Peaches and cream, Lion Cotton, or Bernat's Handicrafter cotton.
hi actually i used peaches and creamso i will buy kitchen cottonthanks for the replysylvia
Peaches and cream IS the same as kitchen cotton. And it will stretch, it's supposed to in a market bag. I thought you meant you used thin crochet thread, not the yarn.
hithen i must have used to big a hookbecause it really stretch outsylvia
What size did you use?


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Ran ki Vav “Awesome view of Rani Ki Vav“
Rani Ki Fave or “Queen’s Stepwell” is a special form of water conservation system, located on the banks of the river Saraswat in the small town of Patan, Gujarat. Rani Ka Vav, considered to be the biggest step of Gujarat, is the culmination of Maru-Gujarat architectural style. The 900-year-old building is featured in a new $ 100 note issued by the Reserve Bank of India, a UNESCO World Heritage Site. JobsGujarat.in Please share this post with your friends. Keep visiting more jobs for course content updates.
Rating Favorite Amazing View Rani Ki vav.
In ancient times, well water had healing properties that helped prevent viral diseases and diseases such as fever. The well was dug in a well-preserved condition in the 1960s, where it was buried under a sanctuary. In addition, the Queen’s Fave was an important center of social interaction for the local population as well as a refuge from the heat. This is an excellent example of turning a functional object into a work of art.
World Heritage Site Ranki Vav Patan Gujarat.
Rani Ki Vav is located at Batan, about 133 km away. This is one of the best CDs in India from Ahmedabad – one of the most famous heritage sites in the ancient capital of Young. This valley or underwater father was built by Rani (Rani) Adiyamati in 1063 in memory of her husband Bhimda I, king of the Solanka dynasty. Vav climbs steps from ground level, which takes you from a series of cold air columns to a deep well. The seven galleries have over 800 elaborate sculptures. The main subjects are classes including Buddha or the ten incarnations of Father Vishnu. On the surface of the water is an idol of infant Vishnu, in which father Vishnu is seated on the head with a thousand covered snakes.
Rate your favorite Queen Staples in Young Gujarat.
Rani Ki Vav, situated on the banks of the river Saraswat. It was built in the 11th century as a monument to the king. Flat wells in the Indian subcontinent are characteristic of groundwater sources, storage systems and were built in the 6th century BCE. From the third millennium. During that time, it was made out of sandstone to process multilevel works of art and architecture. Rani-Ki-Vav was built at the height of the Marvel-Gurjara architectural style of the Bawdi building, which demonstrates the subtle beauty of the sophistication, detail and proportions of this sophisticated technique. Built as an inverted temple, emphasizing the purity of the water, it is divided into seven layers with carved panels of high artistic quality. More than 500 major sculptures, as well as more than a thousand small sculptures, combine religious, mythological, and secular images that are often associated with literary works.
રાણીકીવાવ Amazing Video: Click Here
Ranki Vav is a historical place of India. Mertunga writes about how Queen Udayamati built the Passion House in memory of her husband, King Pemmadja I, who built the great temple of Sun Shiva at Modera. This is appropriate, as the construction of irrigation sites was considered a worthy achievement, especially to pay homage to the memory of the deceased, which is why numerous steps have been taken in West India over the centuries. In the desolate, unobtrusive landscape, these underground structures with their ornate interiors have a powerful effect on the minds of visitors who have the opportunity to place them.


Lashing out at the separatists, Jammu and Kashmir Chief Minister Mehbooba Mufti today alleged they were not allowing schools in the Valley to function because they wanted a new generation of uneducated youths who can pelt stones and can be used as "cannon fodder".
Lashing out at the separatists, Jammu and Kashmir Chief Minister Mehbooba Mufti today alleged they were not allowing schools in the Valley to function because they wanted a new generation of uneducated youths who can pelt stones and can be used as “cannon fodder”.
She said the separatists were exploiting children from the poor families by instigating them to attack army camps, police stations and CRPF camps and were using them as shields, while their own children were safe.
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“If the youths gets education they won’t pelt stones for them. The (separatist) leadership want a generation of uneducated youths who can pelt stones for them,” Mehbooba said in a scathing attack on separatists during a passing out parade of police officers here.
“Today I see that big leaders feel if schools open, poor children will get education and then they will not have time for stone pelting or might not be ready for that,” she said.
Stressing that leaders who give preference to the future and education of the children are needed and not the ones who use them as cannon fodder, she said, “for three months our schools are closed, we tried and even Delhi sent big delegations.
“The reply to the request of a civil society delegation led by Yashwant Sinha, which completed its three-day visit to Kashmir yesterday, was given by burning of two schools,” the chief minister said. “A civil society delegation went to meet them (separatists) and they opened their doors for them.
The team requested them that the future of children was getting spoiled and for God’s sake help to let the schools open and the reply came in the form of burning of two schools,” Mehbooba said.
With the unrest in the Valley continuing for over a hundred days, she alleged that the separatists wanted that the children should get hurt to keep the “pot boiling”.
“They feel that let the children of poor people die. What will happen if they get injured or die they are not rich kids. It is a big challenge for us because till now they have handed over the gun to poor children and now they are using them as shields,” she added.
“Amongst all those killed or injured, 99 per cent were small kids, not one from the rich family, not a single child of those leaders have been injured, only poor kids” Mehbooba said.
She said that first the separatists thought that the uneducated youths would pick guns for them, but the youths in the past 25 years has realised that gun will not solve any problem.
“Children are not ready to pick up guns. Now they want a generation of illiterate children who can pelt stones for them, not only pelt the stones but in the process lose their lives.
“I was told that girl students want to go to school but are afraid that they would be attacked by stone pelters when they see them in the white uniform,” Mehbooba said.


Acetal is typically called Delrin. Formaldehyde when polymerized yields out the product called derlin. It is the chemical composure, its framework and also high crystalline framework of this material which provides a mix of such physical residential or commercial properties that are not available in instance of other products whether it be any plastic or any steel. It is utilized in a number of areas such as the gears.moreover it has actually been made use of in spacers. Its use is not restricted to this just as it has been made use of in washers in addition to manages. Additionally because of the high rigidity as well as strength of these rods, they have actually been utilized in locations where a product has to resist high wearing like in bearing.Different poles have
various residential or commercial properties. For instance Delrin 150 SA is all-natural as well as utilized for conventional and also general functions. Delrin black is equal to the 150 version. This variation of the rod is ultra violet maintained. Delrin 507 has side over the various other variations and also is the best of all the variations.
CNC machining services are very essential as well as there are a variety of these solutions you could pick from depending on the job as well as requires that you have at hand for your items. 5-axis is one sort of solution that you could enjoy from a making company. The machining type entailed right here has 3 direct axes and an additional 2 rotating axes that can take rotary table type or rotary axes on the machine spindle as well as headstock. 5-axis milling is quite an innovative solution, especially for elements that are complicated and require high accuracy. The truth that all attributes are done under one configuration, the precision is much higher.5 Axis machining benefits 1. 5-axis process makes
it extremely straightforward to machine shapes that are complex in one solitary step, thus significantly lowering on machining time, errors and also prices in regards to devices needed for the task handy. You will certainly therefore take pleasure in quicker, accurate as well as economical outcomes for your manufacturing project.Also extremely important to take into consideration are the five axis CNC milling devices that the manufacturing facility has. The higher the high quality of the equipment the extra the consistency you will delight in with the distribution of your product outcomes. The equipments ought to be in leading problem to provide you anticipated outcomes within a short period of time.Service cost ought to likewise be taken into consideration. The prices ought to match the item quality that you obtain in the end. Keep in mind that the raw products used could determine the service fee. Consider what materials the manufacturing facility can take care of and also the demands you have prior to choosing the very best you can afford.The machining team should have the knowledge and experience required for accuracy.


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Best practices in your job search campaign
Friday, February 06, 2015
- 04:00 pm
New York Public Library - Science, Industry and Business Library, 188 Madison Avenue at 34th Street
Lower Level - Electronic Information Center, ETC3 NY,
During this session you will learn about best practices of a successful job search campaign: effective job search planning strategies, marketing yourself, using social networking sites in your job search, making a good impression during the interview, and the importance of follow-up. Online Advance Registration Seating is at 2:10 p.m. for those who have registered for the class. Please arrive early - you will not be admitted once the class has started. Arriving late forfeits your seat. Stand-bys will be accepted if registered participants are not present at the beginning of the event.
188 Madison Avenue at 34th Street
Lower Level - Electronic Information Center, ETC3

domain: library


text:
MADE IN THE UK
Whether you're commuting to work or exploring new trails, our lightweight Travel Pouch is perfectly designed for your small essentials. Fitting neatly in your jersey pocket, frame bag or backpack, it’s a must-have for keeping your smaller items in one place whilst on the go.
The TRAVEL POUCH is made from durable, waterproof TPU fabrics whilst the inside includes an internal card storage area. The YKK Aqua guard zip ensures that your items stay dry, whilst the reflective orange paracord zip pull makes it easy to access. Its cushioned foam structure makes it resistant to the elements.
Finished with our classic PU label.
Hand made in UK Yorkshire workshop


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Playing( 7 )
541 People playing this
- IGN:Minerador Galatico
World of Warcraft
4793 People playing this
Played( 16 )
Wishlist( 1 )
3717 People wish this
Latest Update Photos
Latest Update Blogs RSS
Why League of Legends be the best then Heroes of Newerth?
LoL got some more modules then another game, you be a summoner and you got your personal page, this page you must mount your own build and distribute your runes, this will make you different then another players and this won't happen in games like HoN ( actual f2p ). In LoL be a ballance game with the two modules, random game and party game, in random game do you will meet alone another players in a little bit of level varition, tuning that a very ballanced game, can you change or build to your char do will play before play it. In party game can you invite another players as normal then another games like "Dota". All this differeances make LoL the best in this area.
:D Thanks to reading :D
Be a really great experience to play in paid game are true, but if you search more about free games under your game type will be a good choice experience? Since the new game called "Allods Online" make some players to think about your choices, compared between "World of Warcraft" and "Allods Online"
Make your own conclusions...
The good experience playing World of Warcraft some times ( Special in High levels ) made the game no sense and boring, for this reason so much players search a new type and style of games, one day i play wow another i play Counter-Strike for example, but if this players look for a new game in the same style and type, this answer can be "Allods Online" the new experience and in my opinion the best near game of wow style free 2 play game.
The Secret World Open apply to closed beta in your main website
if you search about this awesome game called The Secret World, you can made one test to apply the CB of the game
If you choose to start a test, will appear some images and questions to answer
Then in final test the result is what group you have more appreciation, and give a menu to choose what group are you want to play.
About The Secret World
The Secret world isn't one game talk about another world or another dimension, he talk about our world but with another vision of then. The secret world will explore the 'dark' places around the world and not only asia ( this is a important point ), the lost places, the far cities and poor streets this will be the focus, the game talk ever this places have one secret history, but if this will be connect i don't know, what i know is about the factions.
If you watch the teasers about the game, can you see smooth about the factions, this factons is, the Templars, illumistis and the Dragons. Have two teasers and the first show the Dragon faction member, the last and second i guess show about the Templars and last will be come will show about il

domain: hobby


Problem: Getting the following errors, when trying to enable foreman-plugin-ansible and foreman-proxy-plugin-ansible.
Expected outcome: foreman-plugin-ansible and foreman-proxy-plugin-ansible enabled without errors.
Foreman and Proxy versions: foreman-3.6.1 and foreman-proxy-3.6.1
Foreman and Proxy plugin versions: foreman-3.6.1 and foreman-proxy-3.6.1
Distribution and version: RHEL 8.7
Other relevant data:
I followed the Foreman :: Plugin Manuals
Following is what I am getting when I run foreman-installer --enable-foreman-plugin-ansible --enable-foreman-proxy-plugin-ansible…
[root@]# foreman-installer --enable-foreman-plugin-ansible --enable-foreman-proxy-plugin-ansible
2023-04-19 17:59:07 [NOTICE] [root] Loading installer configuration. This will take some time.
2023-04-19 17:59:10 [NOTICE] [root] Running installer with log based terminal output at level NOTICE.
2023-04-19 17:59:10 [NOTICE] [root] Use -l to set the terminal output log level to ERROR, WARN, NOTICE, INFO, or DEBUG. See --full-help for definitions.
2023-04-19 17:59:13 [NOTICE] [configure] Starting system configuration.
2023-04-19 17:59:24 [NOTICE] [configure] 250 configuration steps out of 1491 steps complete.
2023-04-19 17:59:28 [NOTICE] [configure] 500 configuration steps out of 1493 steps complete.
2023-04-19 17:59:30 [NOTICE] [configure] 750 configuration steps out of 1498 steps complete.
2023-04-19 17:59:31 [NOTICE] [configure] 1000 configuration steps out of 1502 steps complete.
2023-04-19 17:59:52 [ERROR ] [configure] ‘/usr/sbin/foreman-rake db:migrate’ returned 1 instead of one of
2023-04-19 17:59:52 [ERROR ] [configure] /Stage[main]/Foreman::Database/Foreman::Rake[db:migrate]/Exec[foreman-rake-db:migrate]/returns: change from ‘notrun’ to [‘0’] failed: ‘/usr/sbin/foreman-rake db:migrate’ returned 1 instead of one of
2023-04-19 18:00:04 [NOTICE] [configure] 1250 configuration steps out of 1502 steps complete.
2023-04-19 18:00:10 [NOTICE] [configure] 1500 configuration steps out of 1502 steps complete.
2023-04-19 18:00:12 [NOTICE] [configure] System configuration has finished.
There were errors detected during install.
Please address the errors and re-run the installer to ensure the system is properly configured.
Failing to do so is likely to result in broken functionality.
The full log is at /var/log/foreman-installer/katello.log
Please help, this is a new installation and the installation of Katello was successful, but the foreman-plugin-ansible and foreman-proxy-plugin-ansible are failing.
The foreman version 3.5 and Katello version 4.7 worked just fine for the command “foreman-installer --enable-foreman-plugin-ansible --enable-foreman-proxy-plugin-ansible”, but when I tried to run the command “foreman-installer --enable-foreman-plugin-remote-execution --enable-foreman-proxy-plugin-remote-execution-ssh” it errors with “ERROR: Unrecognised option ‘–enable-foreman-proxy-plugin-remote-execution-ssh’”.
When I checked foreman-installer help, I see the following…
[root@ ~]# foreman-installer --help|grep remote-execution
–[no-]enable-foreman-cli-remote-execution Enable ‘foreman_cli_remote_execution’ puppet module (default: true)
–[no-]enable-foreman-plugin-remote-execution Enable ‘foreman_plugin_remote_execution’ puppet module (default: true)
–[no-]enable-foreman-plugin-remote-execution-cockpit Enable ‘foreman_plugin_remote_execution_cockpit’ puppet module (default: false)
–[no-]enable-foreman-proxy-plugin-remote-execution-script Enable ‘foreman_proxy_plugin_remote_execution_script’ puppet module (default: false)
–foreman-plugin-remote-execution-cockpit-origins Specify additional Cockpit Origins to configure cockpit.conf.
–foreman-proxy-plugin-remote-execution-script-cockpit-integration Enables/disables Cockpit integration (current: true)
–foreman-proxy-plugin-remote-execution-script-mode Operation Mode of the plugin. (current: “ssh”)
Is the “–foreman-proxy-plugin-remote-execution-script-mode” a replacement for “–foreman-proxy-plugin-remote-execution-ssh”?


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A BOOM in baby numbers means Sheffield is to build its first new primary schools in a generation.
Another 840 school places are to be created by two new schools, each costing £5.5 million.
Both will be open by September 2014.
The schools will be based in the north east of the city - but, with no sign of birthrates slowing citywide, planners are not ruling out extra places being created elsewhere in years to come.
The news was welcomed by families with young children who have struggled to secure school places at the primaries of their choice.
And Coun Jackie Drayton, cabinet member for children, young people and families, said: “It is absolutely essential we provide the extra places that are needed.”
The new schools will be on Skinnerthorpe Road in Fir Vale, and on the site of the old Watermead School in Shirecliffe.
The new Watermead will result in the old primary being demolished and a replacement built in its place.
The project marks a change of strategy by education planners, who have been coping with rising birth rates for the last decade.
Schools in other areas of the city are also under pressure, with places scarce in Firth Park, Crosspool, Netherthorpe, Dore and Totley.
Planners are not ruling out that extra places will be needed in those areas in the years to come.
The north east of Sheffield currently has 15 primary schools, offering up to 1,000 reception class places each year.
But more than 1,000 more children entered primary school in Sheffield this term compared with 2001/2.
The response up to now has been to expand existing schools, with over 2,500 extra places created over the last six years.
But councillors will be told next week that continuing the policy is unsustainable with no sign of the birth rate slowing - and new schools are the only option.
Forecasts show pupils will outstrip places from next September in areas including Southey Green, Shirecliffe, Longley, Burngreave, Fir Vale and Firth Park.
Recent Government legislation means both new primaries will be academies, and will need outside trusts to run them.
But council leaders are keen to make sure communities get behind the new schools and let them know how they want them to be run, during a two month consultation period.
Coun Jackie Drayton, cabinet member for children, young people and families said: “We know parents and carers having a direct involvement in schools has a massive effect in driving up standards. That is why it is absolutely essential we provide the extra places that are needed, and ensure there is a strong local voice and character within this process.”
Residents in north east Sheffield welcomed the news.
Farhad Mirzae, aged 22, a bakers’ shop assistant on Barnsley Road, Fir Vale, said: “It’s good news. I have two children aged six and three and getting a school place is very difficult.”
Nawzad Ali, 30, at the Fantastico Barbers on Barnsley Road, said: “It’s great. It will mean more customers for me and, as I have a daughter who is one, the school should be ready when she is old enough to go.”
Security officer Nassar Khan, 23, of Herries Road, said: “A lot of Slovakian people have moved in lately and it has been difficult for them to find places for their children in local schools. This should help.”
Housewife Elaine Williams, 34, of Southey Close, welcomed the Watermead proposals.
“My youngest daughter is four and I am hoping she can get a place in Longley, but it is difficult. A new school will certainly make things easier. I just hope it’s as good as Parkwood where my 13-year-old goes. That’s a wonderful school.”
And Karen Smith, 26, from Southey, added: “It’s great news, and about time too. It’s a big worry finding a school place unless your child has a sibling who already attends.”

domain: sociology


Sophomore Aidan O’Hara and freshman Jenna Egan swept the 200 back titles, while the Loyola University Maryland swimming and diving team captured the women’s 200 and 400 freestyle relay events on the final day of the Thomas Murphy Invitational at Mangione Pool.
The quartet of senior Brianna Keelan, sophomore Tara Mulligan, Egan and senior Erin Calderoni started the day off with a win in the 200 free relay, touching in 1:38.75. Keelan, Mulligan and Calderoni also teamed with junior Liz McKenna in the 400 free relay, winning the event with a time of 3:35.39.
In the 200 back, Egan won the women’s race in 2:08.55, while O’Hara was the first to touch on the men’s side, finishing with a time of 1:52.69.
Freshman Courteney Martin followed that up with a third-place finish in the 100 fly (59.96).
In the 200 free, Keelan and Calderoni finished second and third, respectively, for the women, with Keelan finishing in 1:56.98 and Calderoni clocking in at 1:57.35. For the men, junior Madison Hardimon was third in 1:45.74. Hardimon also checked in third in the 100 free, finishing with a time of 47.63, while Keelan (52.77) and Calderoni (53.78) finished second and third, respectively, in the women’s race.
Loyola finished second and third in both of the 100 back races, with junior Liz McKenna (59.98) and O’Hara (53.02) picking up runner-up honors, and Egan (1:00.11) and junior Zeke Wolfgang (53.73) clocking in third.
In the 200 breast, junior Cara Egan finished third in 2:28.30, and in the 200 medley relay, McKenna, Mulligan, Martin and Keelan finished second with a time of 1:49.51.
In diving events, sophomore Noel Theroux finished second on the 3-meter boards with a score of 261.38 and freshman Maggie Garrahan picked up a third-place finish in 1-meter diving (205.04).
As a team, the Greyhound women topped Boston College, 229.5-140.5, while they fell to Johns Hopkins, 201-163. The men dropped both dual meets to the Eagles, 207-163, and the Blue Jays, 240-124.
Loyola will next host Howard and VMI in a 1 p.m., meet on Saturday, Nov. 8.


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Nicki Minaj’s wax figure unveiling in Berlin has drawn the ire of internet, but here’s the thing — she gave it her stamp of approval … more than 4 years ago. Turns out, the “new” Nicki wax figure at Madame Tussauds Berlin isn’t new at all ……
Queen Latifah says Nicki Minaj will probably come out of her recently-announced “retirement” — but before that, she just needs to live some life first. We got the iconic femcee Sunday heading into a reception hall in North Bergen, NJ for Treach’s…-
Nicki Minaj and 2 Chainz take Barbie tingz to a new level!
BET.com – Latest Videos
France loves starting wars, and might have one with Nicki Minaj now after some angry fans turned on her in the most savage way possible. First off, Nicki couldn’t have been more polite and chill in the way she broke the news to her fans in Bordeaux…-


text:
- freely available
Life 2012, 2(4), 274-285; doi:10.3390/life2040274
Abstract: The evolution of life on earth has been a long process that began nearly 3.5 × 109 years ago. In their initial moments, evolution was mainly influenced by anaerobic environments; with the rise of O2 and the corresponding change in bioavailability of metal ions, new mechanisms of survival were created. Here we review the relationships between ancient atmospheric conditions, metal ion bioavailability and adaptation of metals homeostasis during early evolution. A general picture linking geochemistry, biochemistry and homeostasis is supported by the reviewed literature and is further illustrated in this report using simple database searches.
Observing the space we have come to realize how the history of our own planet began. Today it is common knowledge in cosmology how our sun was formed from an explosion of a supernova and how the interstellar dust that did not collapse into the sun formed, in time, the earth and the other planets of our solar system. Our planet was in fact formed 4.578 Ga (billions of years ago) . Within its first 500 million years the earth rapidly differentiated: the heavier Fe and Ni collapsed into the center, creating the core and the magnetic field of our planet, while an early fast “outgassing” created more than 85% of a primitive atmosphere in which N2, CO2, and H2O were probably already present ; a slower outgassing process continues even today . Besides the H2O coming from outgassing, a smaller portion of water in our planet came from collisions with comets . In a few million years the surface of the earth rapidly cooled down, giving rise to heavy rains that ultimately formed our oceans ∼4.4 Ga ago . The conditions that were created at this time are believed to be sufficient to sustain the origin of life ; additionally, some evidence points to a decreased destructive effect of UV radiation in the oceans due to a shielding effect of the oceanic waters on the first organic molecules and microorganisms . This hypothesis is somewhat controversial in aqueous environment due to the poor absorption of UV by the oceans and still does not explain a putative shielding effect over the first photosynthetic organisms that used visible light and lived in dry environments (e.g., stromatolites? ). On the other hand, those initial times of our planet were immensely violent, and although the water from the oceans probably brought some protection from meteoritic collisions , the repeating impacts of large planetary bodies could in principle caused the extinction of life several times if it existed at all . In fact, the earth debris caused by one of those impacts probably created our moon . The heavy meteoritic collisions ended ∼3.9 Ga ago and they were so intense that there is barely any geological record of the earlier conditions in our planet . Talking about life before this time is therefore a highly speculative exercise. The origin of life in our planet probably passed through synthetic prebiotic processes in which geochemistry slowly evolved into a primitive biochemistry . For several millions of years during these early beginnings there was practically no O2 free in out atmosphere. Profound changes would still be needed in our planet until the rise of our modern O2 rich atmosphere. The effects of these changes on the bioavailability of relevant metal ions and the subsequent effects for metal ion homeostasis are briefly reviewed and commented in this work.
2. Origin and Evolution of O2 on Earth
How our planet became oxygenated is still debated. A usually mentioned cause for this phenomenon is the rise of oxygenic photosynthesis , a process that actually started 200 million years before of the O2 started rising . Other possible explanations are, for example, the abrupt and permanent decrease of oxygen sinks like submarine vulcanism , the change in the composition of volcanic gases  or in the degassing pressure of volcanoes . Whatever the timing and real mechanism of these processes, most researchers do agree in indicating the presence of an initial small quantity of O2  and aerobic respiration  in the early atmosphere. In fact, this initial aerobic respiration was probably instrumental in keeping the relatively low levels of O2 preceding the origin of photosystem II  or whatever combination of causes that lead to the first large and fast increment of O2 ∼2.45 billion years ago and now known as the Great Oxidation Event (GOE) . This first GOE increased only the atmospheric O2, leaving the oceans unaffected , a situation that lasted ∼1.8 Ga when a second GOE that occurred about 0.6–0.8 Ga ago provoked the oxygenation of deep oceans. The global consequences of the GOEs were substantial; e.g., they have been associated with the first two ice ages [23,24]. However, on the biological point of view, different associations can be made: (i) the first GOE probably caused massive extinction of anaerobic life  and an increased O2 related detoxification and utilization capacity , (ii) the second GOE is generally related to the emergence of multicellular life .
Given the current importance of O2 for the life in our planet, the high toxic potential of O2 expressed through metal ion catalyzed reactions and the differential changes in the aggregation states of metal ion redox species resulting from their reactions with O2, it is interesting to examine the biological implications of GOEs. In the next section we start our analysis of these phenomena by resuming the effect of increasing quantities of O2 on the bioavailability of metal ions, concentrating our attention in two prototypical cases: copper (Cu) and iron (Fe).
3. Rise of O2 and Change in Metal Ion Availability
Before the rise of O2 in the atmosphere, the primitive oceans were saturated with several metal ions like Fe2+, Mn2+ or Mo6+ among others , with Fe2+ being the most common among them. The catalytic machinery of early life surely took advantage of these conditions and abundant biochemical evidence of this fact can still be found in bacterial enzymes . On the other hand, the rise of oxygen brought immediate geochemical effects; O2 reacted with soluble iron (Fe2+) in the waters of ancient seas to form layers of insoluble iron oxides (Fe3+), these layered oxides created the mineral now known as banded iron . Independently of the dynamical routes and factors governing the banded iron formation, a final result of this process was certainly a decrease of soluble and bioavailable Fe2+ in the oceans. Contrary to the case of Fe, Cu becomes more soluble when reacting with O2 and passing from Cu1+ to Cu2+ . The drastic changes in O2 and metal bioavailability prototypically exemplified by Fe2+ and Cu1+ constrained early life forms to avoid, adapt, detoxify or use in different ways these elements, and the reason is the paradoxical dichotomy between the toxicity and energetic advantages of O2 mediated processes. A brief exploration of these topics follows.
4. Adaptation of Metals Homeostasis Caused by the Rise of O2
In this section we review a few aspects related to the homeostatic metabolic adaptations resulting from the rise of O2 levels. The included topics will cover the physical-chemical basis of O2 toxicity, the intracellular handling of labile ion pools, the intracellular metal storage mechanisms, the reduction of O2-related toxicity through the control of the oxidative stress, and finally the now ubiquitous but still surprising evolutionary mechanisms of O2 transport using potentially reactive metal ions.
The information in this section is occasionally commented with the help of simple database searches. The use of databases in this mini-review is for illustrative purposes and no absolute claim is done based on statistically sophisticated tests. We performed text data-mining in the Uniprot database , specifically using the Protein KnowledgeBase (UniprotKB). UniprotKB is non-redundant, as experimentally determined identical sequences coming from different sources are represented as a single entry in the database. Using the integrated online services, we performed advanced boolean searches on several fields (e.g., taxonomy, keywords, enzyme classification, metal binding proteins, etc.); all the searches were performed using Uniprot predefined and reviewed fields. We reduced the redundancy of the obtained set of sequences to a final group of canonical (unique) genes per species.
4.1. Basis of O2 Toxicity
The toxicity of oxygen has physicochemical basis in its tendency to acquire electrons from other molecules by non-enzymatic autoxidations. Because O2 cannot accommodate a spin-matched pair, electrons must be acquired one at a time; the breaking up of electron pairs results in free radical formation. Specifically, the one electron reduction of the ground state molecular oxygen produces the superoxide, ·O2− . A second single reduction produces hydrogen peroxide, H2O2, which is not formally a free radical but together with other oxygen free radicals constitute the so-called Reactive Oxygen Species (ROS). A relevant example can be found through the Haber–Weiss mechanism  of the Fe2+ catalyzed Fenton reaction :
We can also write a similar equation for Cu+:
Much of the toxicity associated with transition metals is caused by Fenton chemistry. Although this process is normally referred to the reactions involving Fe, in reality Cu is more toxic for a variety of reasons. Here we mention a few examples: (i) Cu2+ provokes higher oxidative damages than Fe3+ due to higher capacity of Cu2+ to nonspecifically bind biomolecules, particularly through thiol groups , (ii) using several mechanisms of reaction, Cu2+ can promote Fe2+-catalyzed Fenton reactions , (iii) unlike the system Fe3+ + H2O2, the system Cu2+ + H2O2 is able to produce large quantities of ·OH using the following series of reactions :
With the existence of so many deleterious O2-dependent mechanisms, it is not a surprise that, from the evolutionary point of view, the sudden release of large quantities of O2 to the environment has been considered an ecological disaster for primordial anaerobic life . However, it is reasonable to speculate that the formation of banded iron (and the decrease of soluble Fe2+) during the first GOE could have at least contributed to diminish the Fe-associated Fenton damages, maybe even providing some time to develop survival strategies to tolerate the new pollutant.
Interesting enough, when surveying for successful O2-protection mechanisms, we found that in most cases, the problem was solved by directly controlling the metal ions instead of the O2 pollutant. A few representative examples will be reviewed in the next sections.
4.2. Handling Intracellular Labile Ion Pools
As stated in Section 3 and Section 4.1, although both Fe and Cu are transition metals, the water solubilities and O2 related reactivities of different redox species greatly determine the way these metals affect biomolecules. Consequently, different evolutionary strategies have been used to fine-tune Fe and Cu cellular homeostasis. A clear example of these differential strategies can be found in the way free Cu and Fe (labile ion pools) are controlled within the cells.
Intracellular copper ions (Cu+/2+) not bound to proteins are toxic  and as we already described in the previous section. It has even a higher toxic potential than Fe, and therefore in all living species intracellular Cu is tightly regulated. The intracellular concentration of Cu ions are kept close to zero due to the presence of a highly Cu-chelating environment in the cytosol . In fact, using Cu fluorescent sensors, it has only been possible to find kinetically labile Cu pool in the mitochondria and golgi apparatus . When there is a need of Cu, these ions are always transported using Cu chaperons proteins featuring a highly conserved Cu-binding domain (Figure 1) that is also present in other membrane Cu transport proteins like Ccc2 in S. cerevisiae or ATP7A and ATP7B in humans .
On the other hand, recently reviewed evidence  clearly indicates that two main sources contribute to the equilibrium between free Fe2+ and Fe3+ in the cytosol: (i) Fe exchange with the extracellular environment through the cell membrane, and (ii) Fe exchange with intracellular sources such as labile Fe pools in organelles.
There are several other differences between Cu and Fe regarding transport and secretion from the cytosol. Cu expulsion is conducted through a conserved secretory pathway that is fundamentally identical between yeast and humans . In this pathway, Cu is always bound to proteins that share the same basic domain (see Figure 1). Fe can also be transported by proteins in the cytosol, but opposite to case of Cu, no dedicated Fe chaperon has been identified. Instead, from yeast to humans, Fe can be intracellularly transported through bi-functional proteins that also participate in RNA binding [45,46]. Besides this, free Fe can also be secreted directly from the cytosol using cell membrane exporter proteins like ferroportin .
4.3. Intracellular Metal Storage
If metal ions are available in the cell, the inevitable consequence is the increase of Fenton chemistry. Therefore, a primary control mechanism involves “sequestering” free metal ions with metal binding proteins. Considering the relevant role of Fe2+ since the start of life, it is not surprising that Fe binding is a widespread protein function. Probably the best study Fe storage protein is ferritin that has evolved from simpler rubrerythrin-like molecules into a variety of isoforms that are expressed in most Archaea, Bacteria, and Eubacteria . All along their evolutionary history, ferritins have function not only as pure Fe storage proteins; simultaneously they have been involved in free radical detoxification through their ferroxidase activity resumed in the following chemical reactions :
The driving force behind these reactions is the insolubility of the Fe3+ compounds, but this time instead of form banded iron minerals, Fe3+ goes through an alternative mineralization step forming a Fe core in the cavity of ferritin. On the other hand, Cu storage proteins seems to be relatively recent and less specialized than their Fe counterparts; a representative example is the simpler and unspecific metallothioneins (MTs) , which are absent in Archaea. They are present in prokaryotes, but their main occurrences are localized in eukaryotic cells . Structurally, MTs are composed of no more than 60–70 amino acids, and around 30% of them are cysteines. However, the high variability in the size and the sequence of these group of proteins prevent them from been too specific regarding the metal binding capabilities, and besides Cu, they can bind zinc (Zn)  or cadmium (Cd)  but notably not Fe . To illustrate this concept, we show in Figure 2 a plot of the percentages of Fe vs. Cu binding proteins within the three main domains of life found in the Uniprot database . The data seems to indicate that the Cu binding problem is a relatively recent one in evolutionary biology and could probably be associated to the rise of oxygen in the planet.
4.4. Control of the Oxidative Stress
Another way of protecting life from the effect of the Reactive Oxygen Species (ROS) produced by Fenton chemistry is the creation of specialized antioxidant mechanism: e.g., catalases and peroxidases for the elimination of peroxide (H2O2); superoxide-dismutases (SODs) for the elimination of the superoxide (·O2− ). The actions of these enzymes occur through the following general reactions:
The utilization of these types of enzymes per taxa is presented in Figure 3a. While the distribution of peroxidases seems to be similar in the three taxonomic domains, two opposite tendencies are observed for the other antioxidant enzymes: (i) the catalases (which are mainly Fe-containing enzymes) are prevalently used in ancient cell types like those of Archaea and Bacteria, and (ii) from Archaea to the relatively modern Eukaryota there is an increase in the distribution of SODs, which are enzymes that use more Cu and less Fe as we move from Archaea to Eukaryota (see Figure 3b). In fact, it is particularly significant to note that while the Archaea group does not use Cu-containing SODs, Bacteria and Eukaryota use increasing quantities of Cu-containing SODs and decreasing quantities of Fe-containing SODs (Figure 3b). Although interesting, we should not hurry in extracting strong conclusions from these observations. However, it is not difficult to see a tendency in the modern and prevalently O2-exposed cell types (Eukaryota) to increasingly use antioxidant enzymes containing the more bioavailable Cu (SODs) and use less antioxidant enzymes that contain the less bioavailable Fe (catalases).
4.5. Fe-and Cu-Mediated O2 Transport Proteins.
Given the high reactivity of O2 and its propensity for Fenton Chemistry using Cu and Fe (see section 4.1), an absolute absence of these metals in O2 transport proteins would be expected. However, as we show in Figure 4, this is not the case, and several transport proteins of this type exist in nature.
As expected, in Figure 4 we see no evidence of this sophisticated O2 transport mechanism in the relatively ancient Archaean cell types, which evolved mostly in O2 deprived environments. Once again, we find the beginning of this mechanism in the versatile Bacteria domain, although employing only Fe-proteins. However it is in mostly O2-exposed Eukaryotes where this mechanism reaches sophistication and widespread distribution. Prototypical examples are the structure and mechanism of the Fe-containing hemoglobin in higher mammals  and the even rarer case of O2 transporting Cu-proteins that exist only in the Eukaryote domain, the prototypical example being the haemocyanins present in arthropods and mollusca .
5. Concluding Remarks
Life is full of surprises. Even today, biologists are amazed that even at the geologically violent beginnings of our planet it was still possible for life to be created from very modest geochemical principles. In spite of the early challenges to transform a group of geochemical processes in auto-reproducible biochemistry, new geological obstacles were faced by primitive living organisms. One of this obstacles, the rising of O2 in the primitive atmosphere, would in fact change the metal ion bioavailability and force the existing organisms to evolve adaptation of metals homeostasis either to avoid the danger associated with the excess of newly produced O2 or to even manipulate and use O2 in new ways. In this context, the study of the physical and chemical properties of Fe and Cu ions and the determination of their associated metabolic reactions in different organisms help us to improve our understanding of early evolution. The data in the literature seem to indicate that under the new atmospheric conditions, the Fe-based metabolism indeed decreased to give rise to a combination of Fe and Cu-related mechanisms.
The authors would like to thank Prof. Kenneth Towe for his comments in this subject. However, the full responsibility of the opinions stated in this manuscript belongs to the authors. We would also like to thank the referees for the valuable comments and suggestions on our work.
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domain: chemistry


Stuck in a cold rut… UGH! Take a look at the 8 to 14 day temperature outlook. Note that the northern half of the U.S. looks to stay cooler than average for the last week of the Month.
Developing Storm System
A developing storm system across the southern portion of the country will intensify through early next week to bring thunderstorms and wintry precipitation from Texas into the Northeast. Keep in mind that some of the thunderstorms could be a little on the strong to severe side, while some of the wintry precipitation could be problematic for travelers.
Severe Threat Saturday
The Storm Prediction Center has issued a SLIGHT RISK of severe weather for parts of the Southern Plains, including the northeastern part of Texas for Saturday. The primary threat with an thunderstorm activity would be hail and high winds, but an isolated tornado can’t be ruled out.
Here’s a preview of what the radar could look like into Saturday evening/early Sunday morning as a line of thunderstorms develops over eastern Texas and pushes east into the Lower Mississippi Valley. Note also that heading into early Sunday morning, there appears to be some decent wintry precipitation developing along the northern periphery of the storm! This is going to be something to watch!
Severe Potential in Texas
Here’s a ‘Graphicast’ from the National Weather Service out of Dallas/Ft. Worth.
A spring-like storm system will bring a round of rain and thunderstorms to North and Central Texas tomorrow, mainly during the afternoon and evening hours. Some storms will be strong to severe, especially for the red shaded area where the atmosphere will become more unstable. The main severe threats tomorrow are large hail and damaging winds, but there is some potential for an isolated tornado. Rain coverage will be highest across the northern and eastern areas where average rain amounts will be near a half inch to 1 inch. Rain amounts will be more spotty as you head southwest as the coverage of storms becomes more scattered, but again, the storms in this area will be more intense.
See more from the NWS Dallas/Ft. Worth HERE:
Here’s the NOAA 3 day precipitation outlook through PM Monday. Note the heavier precipitation potential across the Gulf Coast States. This heavier precipitation potential will be aided by thunderstorm activity, which again could be strong to severe in spots.
Upcoming Snow Potential
According to NOAA’s WPC, the probability of at least 8″ of snow or more is still fairly high through early next week. Note the probability of at least 8″ of snow or more is greatest near the D.C. area! Stay tuned for more!
The picture above from near near Two Harbors, MN shows a little open water near the shore, but according to the Great Lakes Environmental Research Laboratory suggests that Lake Superior was still 94.2% ice coverage as of Friday, March 14th.
Great Lakes Ice Coverage Update
According to the Great Lakes Environmental Research Laboratory, the Great Lakes Ice Coverage was was still at 85.6% as of Thursday, March 13th. this is down from it’s peak of 92.2% last Saturday, March 8th. The record Great Lakes ice coverage occurred in 1979 at 94.7%.
March Temperature Anomaly
Meteorological Winter was one of the coldest winters on record for a number of states in the Midwest. Interestingly, temperatures through the first half of March have been trending cold for some of the same areas.
Thanks for checking in and have a great weekend ahead! Don’t forget to check me out on Twitter @TNelsonWNTV


text:
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domain: entertainment


text:
... and this post specifically compares Carvels to other local places. The Carvel-specific, general stuff is on the Chains board. Sorry if this post wasn't clear about that before.
If you have kids or want to be a kid again ... get over to the Berkeley store ... To me this beats every ice cream place in the Bay Area including Gelato Milano and Naia down the street. And it REALLY outclasses that organic Straus soft-serve at Picco.
I don’t have to think about and evaluate my ice cream ... just enjoy its flavor and deliciousness.
I personally don’t care WHAT is in Carvel or where the ingredients originate or if it is seasonal. It TASTES good ... and the shop is no-nonsense, pure delight without being cutesy kidsy. All it takes for an ice cream wonderland is good ice cream, colorful cones, interesting novelties and lots of sprinkles and toppings.
Here are the details on the chains board.
Carvel Ice Cream - better than plastic surgery
2516 Bancroft Way
510 – 665-8300
It’s a half a block up from Telegraph on Bancroft ... almost across the street from the Desi hot dog truck.


Beautiful waterfront community on Clarks Hill/Thurmond Lake! This community has paved county roads throughout the subdivision. Some of the features include 4 interior ponds, a nature park and walking trails. There are an assortment of properties available within the community including dockable waterfront lots, ranchette lots, nature estate lots and interior lots. Public water and community sewage. Underground utilities. Site plan is located below. Also below are covenants and restrictions.
Directions: From Evans, take Washington Rd. to Hwy 220 in Lincolnton. Go right 2 miles to stop sign and continue straight onto Maxim Road. Go 2.5 miles to Nathania Farm Road on the right. Continue straight to Serenity Pointe.
Waterfront, Dockable Lots
Interior Lots with Pond Frontage


Dormeo Silver Ion Air Pillow Anatomic
This memory foam pillow is anatomically designed to provide perfect support and comfort no matter how you sleep. The broader side of the pillow is designed for side sleepers, giving more support for your neck and spine, while the shallower profile is ideal for back and front sleepers ensuring your head is in natural position providing deep and restorative sleep. The pillow is encased in a Coolmax® pillowcase that actively draws away moisture providing cooler, dryer and more comfortable sleep, while the open structure Airmesh sides allow hot air to escape from the pillow keeping it fresh all night, every night.
- Dimensions: 30x50cm
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PERTH, WA, SA, TAS, NT, REMOTE & RURAL CUSTOMERS
- For all deliveries of this item, please call 1300 112 337 or email with your postcode for our lowest delivery quote. Our standard delivery cost of $59 to Perth Metro areas relates to the delivery of these mattresses and ensemble bases only.


text:
Hi I'm Caroline (the 'C' in C Seaglass)
I live in the beautiful county of Cheshire in the North-West of England but you will often find me on a beach, elsewhere in the UK, indulging in my passion for collecting ocean artefacts that I can make jewellery or other interesting items from.
I have always loved the seaside since I was a child when I would spend many hours on our family holidays, hunting around in rock pools for interesting shells, stones and wonderful sea creatures.
I love nature and there's something about the sea air that draws me in, whether its on a cold and blustery day in January or a beautiful blue sky day in the spring (we don't get much of a summer here in the UK!)
I will frequently share some of my experiences here on cseaglass.com.
I hope you enjoy visiting my site and find something you like.

domain: travel