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Foot Assessment in People With Diabetes: A Quantitative Diagnostic Approach
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT03089463|
Recruitment Status : Recruiting
First Posted : March 24, 2017
Last Update Posted : September 6, 2018
|Condition or disease||Intervention/treatment|
|Diabetes Diabetic Foot Diabetes Complications Diabetes; Neuropathic (Manifestation)||Diagnostic Test: Observation|
The purpose of this research observational cohort study is to investigate the applicability of using biomechanical assessment in predicting the ulceration incidence in patients with diabetic neuropathic feet. The proposed study will lead to the development of further stratification of high-risk patients into subcategories indicating the vulnerability of tissue to mechanical trauma, which deemed to be the leading cause of ulceration in people with diabetic neuropathy.
As it stands, the current systems used to evaluate the risk of diabetic foot rely on global parameters such as duration of diabetes and glycated hemoglobin to predict the likelihood and risk of diabetic foot ulceration. As ulceration happens as a result of repeat mechanical trauma to the foot that doesn't heal quickly enough due to other complications of diabetes, it is important to include mechanical measurements in predicting the ulceration incident in diabetic neuropathic patients. Despite this, the currently used risk stratification systems do not include biomechanics so by introducing biomechanics it will potentially be possible to predict the ulceration risk by using more local measurements.
The primary objective is to employ the measures of neuropathy, micro/macro-perfusion, and biomechanics of the foot mainly tissue stiffness and plantar pressure to determine the vulnerability of foot to mechanical trauma and ulceration. From the data collected it is proposed that a prognostic risk stratification system will be developed based on the range of parameters collected to identify those that are at highest risk of ulceration incident. Those that are classed as high risk are to be sub-stratified to increase the accuracy of the system in predicting ulceration. This will allow a patient-specific approach to be taken in the prevention of ulcers by providing adequate information to predict ulceration incident. This then can be used to determine the likelihood of an ulcer forming. Furthermore, the possibility of identifying the ulceration site will be investigated.
|Study Type :||Observational|
|Estimated Enrollment :||153 participants|
|Official Title:||Foot Assessment in People With Diabetes: A Quantitative Diagnostic Approach|
|Actual Study Start Date :||November 27, 2017|
|Estimated Primary Completion Date :||December 30, 2018|
|Estimated Study Completion Date :||April 1, 2019|
The entire participants in this study will be included in this group.
Diagnostic Test: Observation
The primary objective is to employ the measurements of neuropathy, micro/macro-perfusion, and biomechanics of the foot mainly tissue stiffness and plantar pressure to determine the vulnerability of foot to mechanical trauma and ulceration. From the data collected it is proposed that a prognostic risk stratification system will be developed based on the range of parameters collected to identify those that are at highest risk of ulceration incident. Those that are classed as high risk are to be sub-stratified to increase the accuracy of the system in predicting ulceration. This will allow a patient-specific approach to be taken in the prevention of ulcers by providing adequate information to predict ulceration incident.
- Qualitative foot assessment [ Time Frame: April 2017 to April 2018 every 6 weeks ]The qualitative assessment is performed to identify if the patient has any foot or Nail fungi, and major foot deformities. Information regarding the toe deformities like clawed toes, hammer toe will also be recorded.
- Skin assessment of the foot [ Time Frame: April 2017 to April 2018 every 6 weeks ]This will be done when the patient lay down on their back on the couch with their bottom of the feet exposed where the measurements will be conducted. Photos will be taken from the plantar surface of the foot. This photos will be used in image processing software to identify any callus, foot and nail fungi and possible ulcers and their size.
- Monofilament test [ Time Frame: April 2017 to April 2018 every 6 weeks ]The next stage of tests will involve testing for signs of neuropathy, which is a loss of sensation in the foot caused by diabetes. To do this the three individual methods outline previously in the scientific background will be used. The 10g monofilament, which is a pen shaped device, which has a single filament similar to that of fishing line. The tip of the filament will be lightly pressed against nine key areas, big toes, middle toes, 1st metatarsal head, 3rd metatarsal head, 5th metatarsal head, left side of the mid foot, right side of the mid-foot, heel pad and the top surface of the foot. If there is a positive reaction then the next site can be examined if the test is negative then the site will be retested to decrease the possibility of error. If the outcome is negative again then it will be noted that they have lost sensation in that region of the foot. This will be done when the patient lay down on their back on the couch with their bottom of the feet exposed.
- Tuning fork vibration test [ Time Frame: April 2017 to April 2018 every 6 weeks ]Next the participant's sense of vibration will be measured using a 128Hz tuning fork. To do this the tuning fork is struck hard enough so that the vibration lasts roughly 30-40 seconds where it will be placed on either their sternum or wrist to get familiarised with the sensation of the vibration. Re-striking the tuning fork every time it will be placed on the top surface of the big toe, top surface of the midfoot and malleolus and with their eyes closed, the participant will be asked if they can feel the vibration and when it stops and the results will be recorded.This will be done when the patient lay down on their back on the couch with their bottom of the feet exposed where the measurements will be conducted.
- Biothesiometry [ Time Frame: April 2017 to April 2018 every 6 weeks ]The final part in checking for neuropathy is biothesiometery or measurement of vibration perception threshold (VPT). This involves a probe that vibrates at different amplitudes based on the amount of voltage supplied, normally up to 50V. As with the other tests the probe will be set to a high voltage setting and placed against the participant's wrist to feel the vibration before moving to their feet. The sites used are very similar to the monofilament test. The vibration will start at a low voltage setting and will slowly be increased until the participant can feel the vibration. Once they feel the vibration, the vibration will be stopped and the participant will be asked if they have noticed that it has stopped. This is to check that they do indeed have sensation in that area. If the voltage reaches 25V and no vibration is felt it can be deemed that the participant has lost sensation in that region.
- Ankle Brachial Index [ Time Frame: April 2017 to April 2018 every 6 weeks ]The next stage is to perform an ankle brachial index (ABI) test to determine if the participant has peripheral arterial dieses. ABI is the ratio between the highest systolic pressure at the ankle and the systolic pressure in arms. This is a common complication of diabetes where the blood vessels in the legs narrow or become completely blocked and as such, the blood flow to the legs decreases. To perform the test the participant will be asked to lie down on the couch and relax for about five minutes after that a blood pressure cuff is applied to the upper arm and a Doppler ultrasound is applied to the brachial artery and the blood pressure cuff is inflated until the blood flow can no longer be heard. At which point the blood pressure cuff will slowly be released until the flow can be heard again. The highest systolic pressure will be used to calculate ABI. For the ankle the blood pressure cuff is placed on the lower half of the shin and the same procedure is followed.
- Transcutaneous oxygen pressure (TcPO2) [ Time Frame: April 2017 to April 2018 every 6 weeks ]A TcPO2 test will also be performed, as this is another form of testing for problems with the circulation in the foot. This is performed with a probe that is heated to 44 degrees Celsius, which causes the blood vessels in the foot to expand, and induces local hyperthermia causing oxygen to pass through the skin towards a cathode. The test will be performed on the common locations for the probe are on the top of the foot, anteromedial calf approximately 10 cm below the knee and the thigh approximately 10cm above the knee. This will be done when the patient lay down on their back on the couch with their bottom of the feet exposed where the measurements will be conducted.
- Skin Perfusion Pressure (SPP) [ Time Frame: April 2017 to April 2018 every 6 weeks ]Another method that may be implemented in measuring the perfusion rate in the foot is that of skin perfusion pressure (SPP) this works by using a pressure cuff and a laser Doppler probe to establish hyperaemia in the area and measures the pressure that the blood returns to the capillaries following a controlled release. To do this a laser Doppler will be placed on the bottom surface of the foot and a pressure cuff will be placed over it. The cuff will then be inflated to 5 mm Hg initially and then the cuff is inflated to 20 mm Hg above the participants' brachial systolic pressure. The cuff is then deflated in 10 mm Hg steps every 5 seconds to a pressure of 50 mm Hg. The cuff is then deflated in 5 mm Hg steps every 15 seconds until the laser Doppler output increases for two consecutive pressure values. The pressure at which this first occurs is considered to be the SPP. This will be done when the patient lay down on their back on the couch.
- Ankle/foot strength - Dynamometer [ Time Frame: April 2017 to April 2018 every 6 weeks ]
For measuring the ankle and foot strength a handheld dynamometer will be used, which measures the peak amount of force that is produced over a movement.
To measure the muscle strength of the dorsiflexion movement the participant will be lying down on their back the participant with their knee held still by the researcher. This is to prevent additional movement and the recruitment of other muscles groups that could influence the results. With the knee now secured the handheld dynamometer is placed across the base of the toes (metatarsal heads) and the participant will be asked to pull their toes up towards themselves as hard as they can for five seconds with one minute rest in between each measurement. This will be repeated three times per foot. The same procedure will be employed for measuring the plantar flexion with the participant pushing their foot as hard as they can into the dynamometer. Again, the same procedure will be followed for testing inversion and eversion.
- Range of motion (ROM) [ Time Frame: April 2017 to April 2018 every 6 weeks ]
To measure the ROM of the ankle a standard goniometer will be used where the participant will be asked to sit up onto the edge of the bed and dangle their feet. For dorsi/plantar flexion the fixed end of the goniometer will be placed on the bony prominence (lateral malleolus) pointing up the shin (fibula) and the participant will be asked to raise or lower their foot as far as they can. The free arm of the goniometer is then moved so that it is parallel with the bottom of the foot (5th metatarsal) and a reading is then taken.
Furthermore a webcam perpendicular to the plane of motion will be used to take images of the foot during maximum plantar and dorsi flexion. The foot will be marked with a skin-friendly pen marker at anatomical landmarks on the medial and lateral side of the foot. This is to facilitate measuring the intersegmental foot range of motion as well as the ankle range of motion during dorsi and plantar flexion.
- Foot Posture Index (FPI) [ Time Frame: April 2017 to April 2018 every 6 weeks ]The participant will be asked to stand so that a foot posture index (FPI) test can be conducted. This is a test, which gives information as to how supinated or pronated the foot is. In simple terms this identifies if a person walks more on the inside of their foot or on the outside. The importance of this test is that it helps identifying the potential areas that are overloaded underneath the foot, and will provide valuable information. To perform a FPI the participant is asked to stand with both feet straight and parallel and the procedure according to Redmond 1998 will be followed.
- Range of motion during walking [ Time Frame: April 2017 to April 2018 every 6 weeks ]Before the plantar pressure test is performed, a number of anatomical landmarks will be marked on the participant's skin using skin-friendly markers. The markers will be placed on the lower extremity i.e. on the leg and the foot. During the test, a video camera will be set up at right angles to the pressure mat to record the gait of the participant. The recordings will be digitised to track the markers. From these measurements the ankle ROM during gait will be quantified.
- Balance [ Time Frame: April 2017 to April 2018 every 6 weeks ]The final test to be conducted is a balance test in which the participant will be asked to stand on the pressure mat with feet shoulder width apart and asked to try and keep their weight in the centre for thirty second and a recording will be taken and repeated three times. They will then close their eyes and repeat the same procedure that was followed for open eyes condition.
- Gait Analyses [ Time Frame: April 2017 to April 2018 every 6 weeks ]In addition to the measurements that are taken in the clinical setting some participants may be asked to participate in gait analyses and in shoe plantar pressure measurements. This would involve a separate session in the Biomechanics Lab at Staffordshire University. As part of the test the participant will be asked to have reflective markers attached to the skin and to walk over a force plate to measure the ground reaction forces and kinematics during movement.
- Ultrasound elastography assessment [ Time Frame: April 2017 to April 2018 every 6 weeks ]Ultrasound elastography allows an assessment of the stiffness of the plantar soft tissues at five different sites of the foot, 1st 3rd and 5th sub-metatarsal area, midfoot and Hallux. To conduct the test an interface material (ultrasound standoff) will be placed between the probe and the skin. This will add cushioning at the interface to prevent the applied force to the probe causing any damage to the foot. By applying minimal compression to the soft tissue through the compliant standoff a series of ultrasound images will be taken. These images will then be used with either elastography to look at plantar soft tissue stiffness.This will be done when the patient lay down on their back on the couch with their bottom of the feet exposed where the measurements will be conducted.
- Blood test [ Time Frame: April 2017 to April 2018 every 6 weeks ]The biochemistry of the participant's blood is also of great importance in the prediction as well as prevention of foot ulcers. These shall be collected with the participants consent from the central database. The parameters of interest are fasting blood sugar, PPBS, cholesterol, triglycerides, LDL, VLDL and HbA1c .
- Thermography [ Time Frame: April 2017 to April 2018 every 6 weeks ]A laser thermometer will be used to assess the locations on the foot that have previously experienced ulcers to look for a temperature difference. If the participant has not experienced a previous ulcer then the 1st, 3rd and 5th metatarsal heads, ball of the foot and the heel pad shall be examined for temperature changes.This will be done when the patient lay down on their back on the couch with their bottom of the feet exposed where the measurements will be conducted.
- Barefoot Plantar pressure [ Time Frame: April 2017 to April 2018 every 6 weeks ]One of the most important measures in this testing protocol is the measurement of plantar pressure. With the pressure mat calibrated the participant will be asked to walk over the mat six times three for the left foot and three for the right. This will allow an average pressure map for each foot to be calculated.
- In-shoe plantar pressure measurement [ Time Frame: April 2017 to April 2018 every 6 weeks ]The participants will also have a pressure sensitive insole placed within their shoe to study the pressure distribution during gait.
- Perfusion measurement [ Time Frame: April 2017 to April 2018 every 6 weeks ]Laser speckle contrast analysis technology will be utilised to study the blood flow on the plantar aspect of the foot. This will be done when the patient lay down on their back on the couch with their bottom of the feet exposed where the measurements will be conducted.
- Ulceration incident [ Time Frame: April 2017 to April 2018 every 6 weeks ]Any ulceration incident and the site of ulceration will be recorded.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03089463
|Contact: Roozbeh Naemi, PhD||+441782 295879 ext 5879||R.Naemi@staffs.ac.uk|
|Contact: Nachiappan Chockalingam, PhD||+441782 295853 ext 5853||N.Chockalingam@staffs.ac.uk|
|Stoke-on-Trent, Staffordshire, United Kingdom, ST4 2DF|
|Contact: David Allan, MSc +441728 294034 ext 4034 firstname.lastname@example.org|
|Contact: Roozbeh Naemi, PhD +441782 295879 ext 5879 R.Naemi@staffs.ac.uk|
|Principal Investigator: Roozbeh Naemi, PhD|
|Sub-Investigator: David Allan, MSc|
|Principal Investigator:||Roozbeh Naemi, PhD||Staffordshire University|
|Study Chair:||Nachiappan Chockalingam||Staffordshire University|


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Prince Harry and Meghan Markle are enjoying their roles as new parents and it’s clear they are committed to giving baby Archie as normal a childhood as possible. The couple has managed to control their son’s exposure in the media, beginning with his first introduction to the world, followed by his private christening.
How Prince Harry and Markle are protecting their son
Prince Harry and Markle, according to one royal expert, are planning “to bring Archie up in as normal a way as possible.”
Royal author Richard Fitzwilliams explained: “Every young royal has the right to privacy when growing up. It is undoubtedly their intention to bring Archie up in as normal a way as possible and it is essential that they be aided in this endeavor.”
Fitzwilliams further shared that “the arrangement has been that in exchange for an occasional photo on birthdays on special occasions they will be left alone and this is obviously likely to continue. Frogmore Cottage is totally secure.”
The royal expert noted how this is evident in their actions,sharing: “Harry and Meghan have shown since Archie’s birth that they aredetermined to have total privacy and this will make their relations with thepress challenging.”
The couple has been under fire for protecting Archie
Keeping Archie out of the spotlight naturally isn’t the most popular idea with fans, who think they shouldn’t shelter him from the public eye.
Fitzwilliams noted: “It’s one thing facing abuse from vilesocial media trolls and the vitriol of caustic commentators, quite another toalienate royal watchers and royal correspondents as they have with theirhandling of the christening.”
Their upcoming Southern Africa trip, according to the royal expert, will be interesting to watch, as well as any visits to the United States, as he noted: “Balancing access and privacy is often extremely tricky and it certainly looks as though it will be for Archie. He is seventh in line to the throne and may well be a role model for many in future years.”
Will fans see more of Archie during their South Africa visitin the fall? Fitzwilliams shared: “Since their handling of Archie’s birth andchristening has been so different to William and Kate’s one must wonder whetherthey will offer the same sort of access on tour which was such a huge successwith William when nine months old and George who was eight, both in theAntipodes and which is manna to the international media but which Harry andMeghan might find too intrusive.”
He continued, “Will they, for example, gave special staged photo opportunities for him? They are without doubt doing things differently and doing things their way. Their intention is also to help others inspired by Diana whose tragic death so affected Harry.”
Prince Harry is ‘fiercely protective’
Prince Harry is reportedly dedicated to giving his son a normal upbringing and is “fiercely protective” of Archie.
A royal insider told Daily Express: “Harry and William had to go through that unbearable grief [of Princess Diana’s passing] not in private but before the eyes — and camera lenses — of the entire world. He was just a kid and he hated it.”
The source added: “Harry is fiercely protective of Archieand has promised him he will never have to go through that. Of course Meghan,who has lived a large part of her life in front of cameras, agreeswholeheartedly. He’ll basically protect Archie with his life.”
Source: Read Full Article

domain: celebrity


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KKday is a site that offers optional tours in more than 53 countries.Find a special experience tour in Japan!
The restaurant that uses fresh “Yamato yasai”, traditional vegetables of Nara grown in the farm under exclusive contract. There are some distinctive breeds in Yamato yasai such as “Katahira akane”, turnip which is red from the leaf to the roots, and “Iwai daikon”, slender white radish, and you can taste the natural sweetness. Besides the vegetables, they also use Nara’s local meat such as “Yamatogyu”(beef) and “Yamatonikudori”(chicken), and the fish “Iwana” grown in torrents of the national park in Nara. This is the restaurant which uses local food and has great cost-performance.
- Uzuraya Club 26, Nakanoshinyacho, Nara-shi, Nara
- Contact No.
- 10-min walk from Nara Station on Kintetsu Line, 20-min walk from Nara Station on JR
- Opening Hours / Holidays
- 11:30-14:30 (Order stops at 14:00)17:00-22:00 (Order stops at 21:00)Closed: Tuesdays
- Official Website
- Time Required
- 30 minutes
- Other Information
- *Average Budget (for one person): Lunch 2,000-3,000 yen, Dinner 4,000-5,000 yenMenu: Yasai biyori 1,650 yen, Yamato no yasai kaiseki Kakashi 3,850 yenCredit card accepted
※ Some information is displayed in Japanese and machine-translated English, which may not be accurate.
For the latest information, please check the official website for each spot.
A healthy restaurant which uses a lot of vegetable of Nara
They use fresh vegetables grown in the farm under exclusive contract and ingredients carefully chosen by the owner from all over Japan. The popular menu is the health conscious lunch and course! They also blend 3 kinds of salt made in Okinawa, Mongolia, and the Andes. You can have melon or water melon for free with the lunch when they harvest them from their farm, so this restaurant is very attractive.
“Yasai biyori”, the lunch with a vegetable main dish
The popular lunch menu is “Yasai biyori” (1,650 yen). This set includes appetizer, various Yamato yasai, ancient rice, pickles, soup and warabimochi for dessert. Since they season the vegetable lightly, you can enjoy its natural taste. So this is a healthy lunch yet has plenty of volume. (The picture is of side dishes of Yamato yasai)
Enjoy all the traditional vegetables of Nara: Yamato no yasai kaiseki Kakashi
This course has more than five dishes mainly using vegetables including appetizer, salad, boiled vegetable and “Mushi Yamato yasai”, vegetable seasoned by 3 kinds of condiments and steamed in an earthen pot. When you order the most reasonable course “Kakashi” (3,850 yen), you can choose from Iwana, Yamato pork and shrimp for the main dish.

domain: food


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Sun printing on fabric lets you use the plants in your garden to create beautiful patterns, and the resulting fabric can be made into clothing or a framed work of art. We teach you how to make a cyanotype with step-by-step instructions.
robin fingerprint cards
Get well soon
chalkboard-inspired gift wrap
Button Greeting Cards: Ideas for Handmade Homemade Card Making

domain: design


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Which Roman landmark was the venue for the world premiere of Mission: Impossible – Dead Reckoning Part One? Amazon Quiz Answers
Explaination – The Spanish Steps Roman landmark was the venue for the world premiere of Mission: Impossible – Dead Reckoning Part One.
The Spanish Steps in Rome, Italy, are a well-known landmark that you may have seen in photographs or films. It’s a lengthy, 135-step stairway that people flock to because it’s both beautiful and historic.
It recently gained notoriety when it was chosen as the location for the inaugural showing of a major film titled “Mission: Impossible – Dead Reckoning Part One.” This indicates that the cast and directors met there for the first time to show the film to the world. Because of its history and beauty, it’s an excellent location for a film premiere. If you like the Mission: Impossible films, you can picture Tom Cruise and the rest of the cast standing on those famous steps.
Note – Don’t forget to search next time “Amazon quiz tophunt” to get new contest answers.
Q1- Which Roman landmark was the venue for the world premiere of Mission: Impossible – Dead Reckoning Part One?
- The Spanish Steps
- Arch of Titus
Answer 1 (A) – The Spanish Steps
Q2- Luna-25 is the first Moon mission of which country in nearly five decades?
Answer 2 (B) – Russia
Q3- Which 2023 superhero film is based on the DC Comics character Jaime Reyes?
- Green Arrow
- Blue Beetle
Answer 3 (C) – Blue Beetle
Q4- Name the fictional character who leads a group of these animals in the ‘Madagascar’ series?
Answer 4 (C) – Skipper
Q5- In which central Asian country is this burning gas crater located?
Answer 5 (B) – Turkmenistan
The Fuzone quiz on Amazon commenced on 21st September 2023 and will be active until midnight 11.59 pm on 21st September 2023.

domain: geography


KJAZZ Radio UK is proud to introduce Sal DiMaggio who was born in a small rural town on the south coast of Sicily.
He moved to San Francisco in the early eighties. Sal and his band specialize in
Smooth Jazz Italian style.
Sal is the owner of RDM Productions and the Producer and Director of the Italian Night Variety Show
Which plays in the Bay area.
KJAZZ Radio UK is proud to introduce two songs from Sal’s collection of material. ‘Autonoise’ & ‘Sax Argent’. We think you are going to enjoy them


UFC superstar is truly a polarizing character in the MMA world. One would think after breaking his leg in the trilogy bout against Dustin Poirier at UFC 264 he would focus on rehabbing his leg back to health. In true McGregor fashion, he’s lighting the world on fire.
The melee began when Nate Diaz teased a possible fight against fellow lightweight warrior, Tony Ferguson. Diaz tweeted a photo of Ferguson holding the UFC Interim Lightweight belt.
McGregor saw said tweet and replied with the a photo of him being interviewed on the canvas after breaking his leg at UFC 264 against Dustin Poirier. He quickly deleted the tweet, but not before the internet grabbed a screenshot.
Many speculated this was a jab at Diaz for choosing to fight Ferguson as McGregor is out for the forseeable future. A fight between Diaz and Ferguson could set up a possible future fight against McGregor.
Then in a strange turn of events, Ferguson entered the conversation and aimed his missiles toward McGregor thus igniting a firestorm.
A fan directed a comment towards McGregor regarding his size and how he is never stepping foot in the octagon again. Ferguson commented on said tweet alleging that McGregor takes growth hormones, is a cheat, and is mentally weak. He also took a personal blow regarding McGregor’s recent alleged DJ beatdown in Italy.
McGregor went postal and retaliated towards Ferguson with some personal jabs of his own referencing the temporary domestic violence restraining order that was placed against him by his wife two years ago after allegedly suffering from a mental breakdown. The entire situation was messy and included his frightened wife calling the police as Ferguson ran away from their home with their son in the pouring rain in the middle of the night.
Ferguson didn’t respond to the above tweet while McGregor continued.
Nate Diaz then threw his hat back into the ring by subliminally tweeting towards McGregor that he’s not even able to fight.
UFC welterweight, Belal Muhammad also took a jab at McGregor implying McGregor is acting like a Twitter thug talking trash to people in the United States while he is half a world away overseas.
In summary, Conor McGregor woke up today and chose violence. Even when he’s not able to fight, he’s still a polarizing character in the sport. Not to be outdone, Nate Diaz is a superstar in his own right and gets the internet excited any time he fights, but McGregor truly incites Twitter wars and it seems as if everyone wants a piece of the pie.
Fans anticipate a fight between lightweights Nate Diaz and Tony Ferguson in the near future, which could be a contender for Fight of the Year as both veterans possess excellent striking and jiu jitsu. It would be a fight for the ages as NorCal (Diaz) takes on SoCal (Ferguson). Can you imagine the fireworks?


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Belleville West reaches state boys basketball tournament
The competition is supposed to be getting tougher for Belleville West. Instead, the Maroons continue to shred it.
Junior EJ Liddell had 26 points and 13 rebounds and three other teammates scored in double figures Tuesday as the Maroons dismantled West Aurora 81-43 in the Class 4A Normal Super-Sectional at Redbird Arena.
The Maroons' victory, their most lopsided of the postseason, clinched their first berth in the final four since the 1965-66 team placed third. West (30-2) will play Elgin Larkin (22-8) in the semifinals of the state tournament at 5:30 p.m. Friday at Carver Arena in Peoria.
West coach Joe Muniz fought back tears as he considered the reality of the Maroons' accomplishment.
"It's been talked about all year long. It's pretty special," said Muniz, his voice cracking. "It's been 14 hard years, and I'm pretty proud.
"We've got two more (games). We've got to go do it."
It will be West's first trip to state since the 2002-03 season, which was before the four-class system was introduced. That year, the Maroons were defeated by Evanston 58-50 in the quarterfinals. It was Bill Schmidt's next-to-last year as coach; Muniz took over for the 2004-05 season.
Senior Malachi Smith had 14 points and nine rebounds, junior Lawrence Brazil III had 13 points and junior Keith Randolph Jr. had 10 points and 10 rebounds as West won its 13th in a row. West Aurora (25-5) saw its 17-game winning streak come to a screeching halt.
The Maroons shot 50 percent from the field (29 of 58) and limited West Aurora to 27 percent (16 of 59).
"We want to beat a team by as much as possible," said the 6-foot-7 Liddell, who in the third quarter became the second-leading scorer in Maroons history, surpassing Mel Patton. "Us playing together as a team, not being selfish, that's how we're going to keep beating teams. We've got two more games to go, so that's our goal."
West outrebounded the Blackhawks 31-11 in the first half and 53-25 in the game. The Maroons outscored West Aurora by a whopping 56-14 in the paint, which helped lead to 22 second-chance points.
West never trailed, taking an 18-10 after the first quarter, 37-17 at halftime and 51-29 after the third quarter when Randolph beat the buzzer with a spin move in the lane. Aurora West never scored more than five consecutive points, and those came late in the game.
"They came out right away, and if they weren't making it, they were rebounding it and putting it back in," West Aurora coach Brian Johnson said. "They were physical and a lot of times overpowered us on the glass. They showed why they're one of the top teams in the state and one of the top teams in the nation."
Johnson said Liddell, who was 6 of 10 from the field and 13 of 14 from the free-throw line, was every bit as talented as he believed. Illinois coach Brad Underwood and Kansas State coach Bruce Weber, who were in the crowd, also had to be impressed.
"Liddell makes his living on the glass and blocking shots, but he opens up with a 3," Johnson said of a top-of-the-key trey Liddell made that put West ahead 5-0 less than one minute into the game. "He gets his own rebounds, he gets everybody else's rebounds. We have rebounds we think we have, and he just takes them. It's an amazing mix they have, and they're so young, too."
Senior Camron Donatlan led Aurora West with 22 points and seven rebounds. Senior Jared Crutcher, who had 26 points and 14 rebounds in the Blackhawks' 82-67 victory over Bolingbrook in the sectional-title game at Romeoville, was held to two points.
"It's called Keith Randolph and EJ Liddell," Muniz said. "Those two guys can take anybody out of a game."
Liddell smiled when asked about becoming the school's second-leading scorer. He has 1,718 points, just eight behind all-time leader Milton Wiley (1,726).
"It means a lot. I've got to go out and get first place now," Liddell said. "I've got two more games. It would mean a lot to beat Milton Wiley. He was a great player at our school."
Muniz senses the Maroons are ready for more.
"This group is special," he said. "They're not afraid of the big stage. We prepared them for this because of the schedule we've played. The bigger the game, the better they play. And No. 32 (Liddell) always rises to the occasion in big games. He's so smooth. The stage is never too big for him.
"We still haven't played our best game. I keep telling them that. We're striving to get better and better every night. The one thing about this group is they haven't quit practicing. They still get after it, and that's why we've gotten better as the season's gone on. And in the postseason, we've taken it to a whole other level."

domain: news


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Game Questions & Answers (Q&A) service lets you ask questions about video games for game consoles or PC games. So ask your Batman: Arkham City question for Playstation 3 and get answers from real gamers or answer questions and share your insights and experience with the rest of the gaming community.
- Developer: Rocksteady Studios
- Publisher: Warner Bros. Interactive Entertainment
- Genre: Action Adventure
- Release: Oct 18, 2011
- ESRB: Teen
Question & Answers
How to climb when gliding
How do you climb when gliding during the demon trials?
Answer from: skinner
Keep heading towards the ice and press rb

domain: game


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Plantar Fasciitis Treatment In Burlington
What Is Plantar Fasciitis?
Plantar fasciitis is an inflammation of the fibrous tissue along the bottom of your foot that connects your heel bone to your toes. Plantar fasciitis can cause severe foot pain if left untreated. It will affect mainly the heel.
What Is The Main Cause of Plantar Fasciitis?
Plantar fasciitis or foot pain is mostly caused by repetitive movement of the ligament connected to the foot. Such movement can be from excessive running or walking, inadequate footwear, and/or creating an injury from jumping.
Plantar fasciitis treatment doesn't require a lot of exercises. Below, we explained the process. As long as you are committed, you will recover.
How To Avoid Getting Plantar Fasciitis?
To reduce the pain of plantar fasciitis, try the six recommended tips:
- Maintain a healthy weight.
- Choose supportive shoes.
- Don't wear worn-out athletic shoes.
- Roll a ball under the sole of your feet.
- Apply ice.
- Stretch your arches.
Factors That Increase Chances of Getting Plantar Fasciitis
While plantar fasciitis or foot pain can develop without an obvious cause, some factors can increase your risk of developing foot pain. They include:
- Age. Plantar fasciitis is most common in people between the ages of 40 and 60.
- Certain types of activities that place a lot of stress on your heel such as long-distance running or aerobic dance.
- Foot mechanics. Flat feet, a high arch to name the most common ones.
- Obesity. Excess weight put more stress on your feet.
- Professions that keep you on your feet. Teachers, waiters, construction workers for example. It can increase the risks to have plantar fasciitis or foot pain.
If you do get foot pain, get quickly the plantar fasciitis treatment our clinic provide. It will definitely help in reducing the pain.
How Long Can Plantar Fasciitis Last?
Plantar fasciitis usually resolves within 4 to 18 months without medical treatment. However, for some people, plantar fasciitis can become a chronic condition. Medical attention is recommended.
Symptoms may disappear and then appear again, or the foot pain may remain consistent for a year or longer. It really depends on the strain you are putting on your feet and if you are minimizing the risk factors.
What Happens If Plantar Fasciitis Goes Untreated?
If plantar fasciitis is left untreated, it can lead to other issues in the body. While heel and foot pain can make walking difficult, it can also cause an imbalance in the way you walk resulting in lower back pain and/or other areas of the body.
Plantar Fasciitis Treatment
Plantar fasciitis treatment are effective but requires taking home exercises to stretch the plantar fascia and Achilles tendon. Stretching these areas will make the symptoms less severe and less likely to recur.
Our chiropractor or physiotherapists at our Burlington clinic can assess you during the first visit and start treating the injury during the same appointment.
It will involve some exercises such as strengthening and manual therapy. These exercises should focus on the plantar fascia and Achilles tendon, which connect the toes to the heel bone.
Dr. Maggie can guide you in these exercises, as well as help you strengthen your lower leg muscles to help stabilize the ankle.
In addition to stretching, shock wave therapy or similar may be used to reduce the force placed on the tissue when walking. The use of a tennis ball is also effective in treating foot pain such as plantar fasciitis.
The most common form of treatment involves a combination of conservative methods and physical therapy.
Can Orthotics Help Reducing Foot Pain?
Yes, it does very much so. In fact, it’s highly recommended to use custom-orthotics if you have chronic foot pain or flat feet or deformities that causes you to have some mobility issues.
You can read more HERE for more information on custom orthotics.
Foot Pain Recovery
While most patients will recover from plantar fasciitis on their own within a year, it is important to seek medical advice if symptoms persist for more than a few weeks. An ultrasound of the foot can reveal a thickened plantar fascia, which could be an indication of inflammatory changes. If the patient continues to have symptoms, it is best to seek medical treatment. However, there is no one specific treatment for plantar fasciitis.

domain: medical


Intel is conducting an interview for the post of CAD PDK Runset Development Engineer.
Job duties and responsibilities:
- In this job he/she will be involved in backend design verification code.
- DRC like runsets generation and debugging
- Key Aspects will be Layout tools Virtuoso Calibre, DRV IC Work Bench
- Runset Development Calibre PVS ICV Scripting Perl Python or TCL
- The candidate needs to have a minimum of 1 years of experience in the VLSI back end domain.
- He/she needs to have hands on experience on Layout editing tools
- CAD scripting languages like Python, Perl, TCL and knowledge of runsets will be an added qualification
- Candidate needs to have strong debugging skills and needs to be a team player demonstrating strong customer commitments
- BS or MS in Electrical/Electronics engineering 1 years of experience is required in the physical design verification is required
- Strong experience in developing the physical rule runsets in IC VCalibre is very much required
- Exposure to multi foundry technologies from TSMC Samsung Global and other competing foundries is very much desired
- Strong management experience in managing the developers QA engineers and other stakeholders is expected
- Intel technology exposure from the past experience will be a real plus
Job/Req. ID: JR0170935
Location: Bangalore, KA
Join all India Electronics Jobs WhatsApp Group


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In the city of Brotherly Love, Mita Sweet Lips Cruz, a young Latina woman, never had the chance to enjoy her youth. After surviving a vicious rape at the hands of her stepfather on her fourteenth birthday, she desperately searched for some meaning to her Damaged Soul in the streets of North Philadelphia. After developing a relationship with a widow, Mita Sweet Lips Cruz was beginning to feel the unconditional, love that she didn't get at home, only to discover that she was carrying the seed of a rapist, a man who paid her crack whore mother to enjoy her young wound. With an ugly future ahead of her after giving birth, her new born child is put up for adoption. Lives are lost, and Mita Sweet Lips Cruz is forced to spend the rest of her youth in a state prison. FBI Special Agent Jasmine Rodriguez was considered a rising star within the FBI, elite, with the distinguished honor of being the youngest FBI, agent in a city that had witnessed its share of corruption amongst law enforcement. She's an expert in running sting operations, from corruption to child pornography, but no matter how successful she was in her professional life, she couldn't run from her shady past. When she crosses path with a recently released murderer, her devious sexual desires make her lose focus of her oath. Her life changes tragically, and hidden agendas will be revealed. Indisputably, DAMAGE is a gritty and raw urban thriller which grabs you from the very first page and won't let you go until the very end. DAMAGE takes the urban fiction genre to the next level.
"synopsis" may belong to another edition of this title.
Book Description New Vision Publications. PAPERBACK. Book Condition: New. 0982677235 New Condition. Bookseller Inventory # NEW7.1509583
Book Description New Vision Publications, 2010. Paperback. Book Condition: New. Never used!. Bookseller Inventory # P110982677235

domain: literature


C18.4 - Flannel - wine plaid *
Fabric Name: Flannel - wine plaid* (a 1 star fabric)
Content: 100% cotton
Description: This is a cozy soft, brushed flannel fabric. It is a standard flannel shirt weight, 4 oz. It is a yarn dyed (not a print) plaid pattern of wine, cream and denim blue (looks great with jeans!).
Care: machine wash / tumble dry or hang dry to avoid shrinkage
Shrinkage: vertical 5% / horizontal 5%
*if you hang your garment to dry instead of machine drying it, you do not need to worry about shrinkage.
Items that work well in Cotton Flannel fabric. Mannequin shows the Zip Front Robe PW14.
*we check each and every order that comes in for fabric / style compatibility. If something seems off, or we just don't think the selection is good for the style, we will definitely contact you to discuss options.


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If you are interested, please contact us!
The gas chromatograph inlet septum is referred to as the injection pad and is one of the key components for introducing the sample into the column in the gas chromatograph analysis test. During the gas chromatograph injection process, the sample to be tested can flow through the column with the gas flow only when the carrier gas pressure in the column reaches a certain height. Here, the role of the injection pad is to keep the gas chromatograph system in a sealed state, to separate the sample flow path from the outside to prevent air from entering the system or sample leakage, and to keep the internal pressure of the chromatographic system stable.2ml gas chromatography vials
The injection pad is generally made of silicone rubber with high temperature resistance and good air tightness. The standard for selecting the inlet septum is usually based on the upper limit temperature detected by the gas chromatograph. In general, the lower temperature limit of the sample pad is softer and has better sealing, which is higher than the upper temperature limit of the same type. Compared with the pad, the puncture resistance (injection) is good. However, if the injection pad is used above the recommended temperature, the sample pad will leak or decompose.
The injection pad is a lossy accessory in the gas chromatograph analysis system. After a period of use, there may be air leaks or other abnormalities. The injection pad is damaged as follows: 1 Injecting gas leakage, during the gas chromatograph detection injection process, the injection needle will cause a certain degree of damage to the injection pad and leaking; 2 decomposition, the column is separated When some high boiling point samples are tested, the column temperature will be relatively high. At this time, the sample pad will be slightly decomposed under high temperature conditions; 3 sample loss, once the sample pad is damaged, the sample will be lost; 4 column The internal flow rate is reduced and the efficiency of the column is decreased. When the injection pad leaks or is decomposed, the pressure inside the column is unstable, so that the carrier gas flow rate in the column is lowered, and the column separation degree is lowered. 5 The peak is abnormal, once the chromatogram The column separation is affected, the electrical signal of the substance detected by the detector is not accurate, and the formed chromatogram is abnormal, forming a ghost peak.2ml gas chromatography vials
The performance of the injection pad affects the accuracy of the gas chromatograph test results. Therefore, when the injection pad is damaged, it should be replaced in time. When should the gas chromatograph injection pad be replaced? In addition to the above phenomenon, you can also use the TCD detector to detect, in the case of no injection, there are regular small peaks on the recorder, indicating that the gasket leakage has been replaced. Replace the septum so that it is not too tight. Generally, it will be at normal temperature when it is replaced. It will be tighter after the temperature rises. If the septum is tightened too tight, it will cause difficulty in injection and it is easy to bend the syringe needle.
Although the injection pad is a small accessory in the chromatographic analysis, it can reduce the damage caused by a little attention during use. How to solve the unnecessary loss of the injection pad?2ml gas chromatography vials
1. Use in the high temperature range of the septum. The injection pad is generally made of silicone rubber. Silicone rubber has higher heat resistance than ordinary rubber. It can be used almost at 150 degrees without performance change. It can be used continuously for 10,000 hours at 200 degrees. It can also be used for a while at 350 degrees. Therefore, the selection of the injection pad must take into account the high temperature upper limit of the sample analyzed by the gas chromatograph, and try to use it within the temperature limit to avoid overheating decomposition;
2. Try to use an autosampler to reduce damage to the injection pad;2ml gas chromatography vials
3. Use a sharp-pointed syringe to reduce the area of force;
This is the end of the introduction of Gas chromatograph injection pad replacement requirements. I hope it can help you.

domain: chemistry


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He is cute. He's shrewd. The girls love him. The cops hate him. He can't speak but is always talked about. His naughty antics will make you scream, but he will never listen. Cos he can't! Next summer ride a rollercoaster of emotions with Barfii - the Chalu Chaplin!
Aakhari Decision is a Bollywood action film directed by Deepak Bandhu and starring Anant Jog, Nagesh Bhonsle, Mushtaq Khan, Navni Parihar, Amar Sidhu, and Sumona Chakravarti. It was filmed in India and the United States.
The paths of a man and a woman, who have both been recently divorced from their spouses, intersect at an art exhibition in London.
An adrenaline junkie walks away from a whirlwind romance and embraces a new life as a thief, though he soon finds himself pursued by veteran police officer and engaged in a turf war with a local gangster.
A young woman falls in love with a handsome playboy, while aboard a Singapore to India cruise. They make plans to meet again, but fate may have other plans...
Comedy Nights with Kapil is a comedy show which provides a distinctive take on the everyday life of a common man as the show explores the story of every household and how our common man Kapil is affected by the simplest issues in life around him.
Comedian Kapil Sharma interacts with celebrity guests about their latest films while keeping the audience laughing with his wit, humour and assorted skits.
Showcasing stories inspired from real life events, this fictionalized investigative thriller plunges viewers into the world of Dev Burman - a detective who is an enigma in himself.
Bade Achhe Lagte Hain is an Indian television drama series which premiered May 30, 2011 on Sony TV and airs Monday through Thursday. It is based on the Hindi novel Patrani by Imtiaz Patel. The drama explores the worlds of two personalities: Ram Kapoor and Priya Sharma, who accidentally discover love after they marry. The series is produced by Ekta Kapoor of Balaji Telefilms and stars Ram Kapoor and Sakshi Tanwar in the lead roles.
A talk show hosted by Rajeev Khandelwal.

domain: entertainment


2014 Ram Power Wagon - Factory Fresh
America's Beloved Mass Production 4x4
The past few years have been busy for Ram with some major updates to the 1500 line in the form of a new eight-speed automatic transmission, a new base V-6, and mpg-champ EcoDiesel. The HD line also got some significant updates as well with a new coil spring rear suspension and an optional new 6.4L Hemi V-8. But everyone still wanted to know: What about the Power Wagon? Well, now we know.
The modern iteration of this iconic nameplate debuted in 2005 to widespread critical and enthusiastic acclaim. The Power Wagon’s basic formula—based on the gasoline Ram 2500 Heavy Duty 4x4 crew cab—carries forth, but with some significant updates for 2014. Three trim levels (Tradesman, SLT, and Laramie) determine exterior and interior design treatments. Up to 12 different colors will be offered.
Optional on other 2014 Ram 2500 and 3500 models, the ’14 Ram Power Wagon gets the new 6.4L Hemi 16-valve V-8 as standard equipment, boasting 410 hp at 5,600 rpm and 429 lb-ft of torque at 4,000 rpm. The transmission is a 66RFE six-speed automatic, which connects to a part-time, manual-engagement BorgWarner BW 44-47 transfer case. The axles are built by American Axle Manufacturing: a 9.25-inch in the front and an 11.5-inch in the rear, both of which include electronic locking differentials available in low range. Power is delivered via a 4.10:1 ring-and-pinion ratio. The axleshafts measure 38 mm in the rear and 35 mm in the front. New for 2014 is the segment-exclusive front axle disconnect system across the Ram Heavy Duty truck line.
The three-link front suspension features Bilstein monotube shocks, more than 2 inches of lift, and the “Ram Articulink” design, which incorporates high-movement joints at the control-arm-to-axle mount for additional flexibility and axle articulation. Further enhancing off-road agility is a class-exclusive electronic disconnecting sway bar, which can be disengaged in-cab via the driver-actuated “Smart Bar.” With the sway bar disconnected, the off-road ready Ram reaches 510 on a Ramp Travel Index (RTI), or 26 inches of vertical height. The Power Wagon’s rear suspension is the segment-exclusive, all-new five-link coil system found on all Ram 2500 HD trucks, with the addition of Bilstein monotube shocks. Some models have an additional Bilstein damper that links the top of the rear axle to the frame. Payload is up to 1,490 pounds and towing capacity stands at 10,810 pounds.
The 2014 Power Wagon will be equipped with 33-inch Goodyear Wrangler Duratrac tires, contributing to 14.5 inches of ground clearance—2.5 inches more than the Ram 2500 HD. A 34-degree approach angle, 23.5-degree departure angle, and 25.5-degree breakover angle make the Power Wagon agile on the trail. The underside is adorned in skidplates to protect from damage. The frame, which is built with high-strength 50,000-psi steel, is highlighted by eight separate crossmembers, hydroformed main rails, and fully boxed rear rails. As on all ’14 Ram Heavy Duty trucks, the Power Wagon has four-wheel disc brakes with front rotors measuring a beefy 14.17 inches and rear rotors 14.09 inches. A dual-alternator system contributes to 380 amps of total best-in-class output. A Warn 12,000-pound electric 3/8-inch steel cable winch tucks elegantly inside the front bumper. The bonus of a really cool factory off-road truck? You got it: a standard three-year/36,000 Basic Limited Warranty and a five-year/100,000-mile Powertrain Limited Warranty.
Claimed by Ram as the most off-road capable pickup truck in the market, the 2014 Ram Power Wagon will continue to be built at the Saltillo Truck Assembly Plant in Coahuila, Mexico. With destination fees included, pricing will be $45,690 for the Tradesman, $50,340 for the SLT, and $56,015 for the top-of-the-line Laramie.
|Inside the Build|
|Type:||6.4L Hemi OHV V-8, with variable-valve timing (VVT) and cylinder deactivation|
|Horsepower:||410 at 5,600 rpm|
|Torque:||429 at 4000 rpm|
|Recommended Fuel:||Regular Unleaded|
|Layout:||Front engine, 4WD|
|Transmission:||66RFE six-speed Automatic|
|Brakes:||14.17-inch vented front with twin-piston calipers/14.09-inch vented rear with twin-piston calipers|
|Tires:||285/70R17 Goodyear Wrangler Duratrac|
|Tow Capacity:||10,810 pounds|
|0-60:||8.2 seconds (est.)|
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We Drive the Tiny, Forbidden Lexus (Because You Can't)


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The project started up in November 2001 and is scheduled to finish in November 2003. It involves the development of:
This project shall be developed by a partnership consisting of nine European bodies, conducted and coordinated by INITIATIVE ECONOMIC DEVELOPMENT (Eire). Within the partnership, ITURBROK (Spain) shall collaborate with Kingston University (United Kingdom), Northern Ireland Economic Research Centre (United Kingdom), EWEDO GGMBH (Germany), Associaçao Industrial Portuguesa (Industrial Association of Portugal / Chamber of Commerce of Lisbon - Portugal), The Circa Group (Eire), Laois County Enterprise Board (Eire) and Iniciativas Innovadoras (Innovative Initiatives - Spain).
|CIBERAULA JUS LA ROCHA|

domain: economics


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GTA V: DJ Solomun’s new video clip shot in-game
A week ago the players of Grand Theft Auto V welcomed back the charismatic *** Tony, a character introduced in the older GTA IV and returning as the protagonist of the new expansion of GTA Online, entitled After Hours.
Well, with the debut of the DLC, the world of GTA Online has welcomed many new content and characteristic characters. Among the latter also appears Solomun, famous Bosnian disc jokey who, for the occasion, presented the music video of his song Customer Is King. Why are we talking about it? Simple: the video clip was shot entirely inside Grand Theft Auto V. Seeing is believing.
GTA Online: the customer is King
The music clip was made by Rockstar Games, who shot and directed the film in close collaboration with Solomun and his Diynamic Music label. For the videogame producer this is the first partnership signed with an artist to launch his musical works, with Grand Theft Auto V which acts as a real launch pad.
The video of Customer Is King wants to tell a completely new story, but always connected to the original events of GTA V, basing everything on motion capture sequences and customized animations. The protagonist is therefore Solomun, struggling with another, hard day of work. We see him making deliveries for everything Los Santos, in a vain attempt not to be overwhelmed by the daily chaos of the city.
The result? A surprising mix of action – in pure GTA style, in short – and pure spectacle, with an impeccable dance sound accompaniment, of course.
Rockstar anticipates that in the coming weeks we will see the creations of other musical artists, whose virtual counterparts also reside in that of Los Santos. The next appointments are therefore with the group Tale Of Us, with Dixon And The Black Madonna.


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Poster Award for Casper Webers
On 30 September Casper Webers won the Poster Award for his poster titled 'Valuing treatment with infliximab for ankylosing spondylitis using a willingness-to-pay approach'.
The award was granted during the closing ceremony of the annual meeting of the Dutch Society for Rheumatology and was accompanied by a check worth €750.
Classically, the effects on medical interventions on health of patients with inflammatory rheumatic diseases are assessed by patient reported outcomes that address disease specific health domains. A 'Willingness To Pay' (WTP) is an alternative approach to value the overall improvement of health due to the treatment.
In a hypothetical situation where patients should contribute financially to continue treatment, 74% of patients were willing to contribute. The majority of the remainder patients objected to the idea of co-payments.
The WTP as well as amount willing to pay were related to the health benefits patients had experienced. As such, a WTP approach offers an interesting valuable alternative approach to value health benefits.
Casper Webers is a 2nd years PhD candidate at the department of Rheumatology and his research is embedded in the research line Functioning & Rehabilitation.
In the upcoming months, the Faculty of Health, Medicine and Life Sciences will share tips on Instagram on how to live a healthier life. Not just a random collection, but tips based on actual research happening at our faculty. The brains behind this idea are Lieve Vonken and Gido Metz, PhD candidates...
Berta Cillero Pastor is an Associate Professor and group leader at the MERLN Institute for Technology-Inspired Regenerative Medicine. Her research is centred around mass spectrometry (imaging) to gain insights into molecules in cells and tissues for biomedical research. With this technique, changes...
Scientists at the biomedical MERLN Institute of Maastricht University and the Maastricht University Medical Center have succeeded in growing an embryo structure of human identical twins purely from stem cells, without using an egg or sperm cell. Thanks to this culture, scientists are now seeing for...


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Royal Botanic Gardens | Peradeniya
Royal Botanic Gardens, Peradeniya are about 5.5 km to the west of the city of Kandy in the Central Province of Sri Lanka. In 2016, the garden was visited by 1.2 million locals and 400,000 foreign visitors. It is near the Mahaweli River (The longest river in Sri Lanka). It is renowned for its collection of orchids. The garden includes more than 4000 species of plants, including orchids, spices, medicinal plants and palm trees. Attached to it is the “National Herbarium of Sri Lanka”.
Photos and Videos Credit goes to the Department of Botanic Gardens.

domain: travel


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Monday, December 05, 2005
It's a Wrap!
Production wrapped on the no-budget, 3 minute short Super 8 film Holly Dazed. As co-producer, camera-person, light supplier and part of the creative team, I would like to thank the rest of the cast (Sam, Scott, Amanda and Markus) and crew (Lynn, Steve and Glen's mom's sweater) for all their hard work and dedication on the project. Also the various locations (Alantic Film Festival, Profac, CBC Radio Canada, Chadwick Foods, Kick Ass Shoes, Nubody's and the Park Lane Parking Garage) that put up with our shenanigans. A big fat "no thank you" to Alexandra's Pizza for taking about two hours to deliver two medium pizzas. Another shout out to Amy at The Maxwell's Plum for serving us during our impromptu wrap party event, about 5 hours after we began shooting. The film was produced for the Atlantic Filmmakers Cooperative's annual Super 8 Holiday Party and Screening taking place on December 15, 2005 at the Seahorse Tavern (9 PM). Fingers crossed...I just hope it is in focus. And there was enough light. And it is funny. And why didn't I take any pictures? Damn.

domain: artistic


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08/10/16 - 12:01am
Girls fastpitch softball team seeking players
The Georgia Fusion girls fastpitch softball organization is having open tryouts for the 2016-17 season for ages 10U-14U from 10 a.m. to noon Saturday, Aug. 13, at Greenbrier Middle School. Especially needed are pitchers and catchers. Contact coach Jason Huffman at (318) 780-9129.
Rec department holding fall sports registration


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An angry tweet from an enraged customer is the tag to a clever new campaign promoting KFC’s often maligned fries.
The tweet read: “Dear KFC, No one likes your fries. Yours sincerely, The Entire World”.
Now KFC in the UK – fresh from its marvellous “FCK” campaign earlier in the year – has used the tweet in a series of outdoor and print ads to promote the pending arrival of its apparently vastly improved chip.
The tweet first appeared via an unknown chap who goes by the username “Upgrade”.
Soon, other tweeters were jumping on the anti-KFC chip crusade.
Even KFC’s competitor Burger King was soon in on the action, too.
But the chicken chain’s London agency Mother soon turned the hatred into a campaign to promote the new fry that is reportedly “chunkier, tastier and better”.


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Posted 24 сентября 2020,, 12:58
Published 24 сентября 2020,, 12:58
Modified 24 декабря 2022,, 22:38
Updated 24 декабря 2022,, 22:38
The tests will be carried out by the State Commission for Radio Frequencies (SCRF). Its task is to find out if the use of this technology interferes with the operation of other devices. Previously, this technology was not used in Russia due to the prohibition of the SCRF (GKRCH).
“This technology was not used in Russia because its power exceeded the standards that exist for portable devices. In fact, the problem is that the technology does not fit into the regulations that exist today and which are unlikely to be changed for Apple”, - said Eldar Murtazin, an analyst of the mobile communications market, editor-in-chief of the mobile-review.com portal, in an interview with Sputnik radio.
According to him, now the company will try to prove that there are no problems with the use of this technology. After testing, the regulator will either allow the company to use this technology, which means it will have to change regulations, or the use of this technology will remain banned.
Earlier, Apple announced the blocking of Russian media applications in the Ukrainian segment of the App Store at the request of the Security Service of Ukraine. The Russian Foreign Ministry urged not to follow the lead of the Ukrainian authorities and not block applications. According to the Russian Foreign Ministry, the demand of the SBU "violates the country's international obligations in the field of freedom of speech and expression".

domain: law


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European stocks were expected to open higher on Monday following amuch anticipated summit of European leaders on Sunday, where policymakers edged closer to an agreement on recapitalization of the region's banks and details relating to the European Financial Stability Facility.
Financial spreadbetters expected Britain's FTSE 100 to open 41 to 62 points higher, or as much as 1.1 percent, Germany's DAX to rise 44 to 68 points, or as much as 1.1 percent, and France's CAC 40to gain 22 to 35 points, or as much as 1.1 percent.
In Asia overnight, stocks rose on news of progress from the summit in Brussels, but concerns linger over the extent of losses private holders of Greek government bonds will have to bear.
Final agreements have been delayed until Wednesday, but the disagreement between French President Nicolas Sarkozy and German Chancellor Angela Merkel over the European Financial Stability Facility's relationship with the European Central Bank seems to have been resolved, with Sarkozy backing down on his desire to use unlimited ECB funds for bailout purposes.
Dow Jones reported late on Sunday that there is growing consensus among euro zone leaders that banks will have to take a haircut of around 50 percent on their Greek bond holdings.
An unnamed source said Germany and several other euro zone nations favored haircuts of up to 60 percent, but France with significant assets in Greece, wanted a haircut of around 40 percent.
Dutch bank ABN Amro has promised to buy the financial assets of struggling euro zone banks, the FT reports on Monday.
In an interview, CEO Gerrit Zalm says he has "spoken to almost all" of ABN Amro's European rivals about the plan and the newspaper claims the move is an attempt for the now nationalized Dutch bank to rebuild itself as an international bank.
French President Nicolas Sarkozy is expected to give a TV interview on Monday with French channels TF1 and France 2 on the Brussels summit over the weekend and ahead of the final G20 meeting in Cannes in November.
In London, Members of Parliament are set to vote on whether the UK should hold a referendum on its membership of the European Union in light of the ongoing debt crisis in the euro zone.
All three leaders of the main parties have said they will vote against the motion, which is expected to be supported by many within the right wing of the Conservative Party, the so-called euroskeptics.
Swiss parliamentary elections are also due to take place on Monday.
Key corporate data out of Europe on Monday includes third quarter results for satellite navigation maker Tom Tom and Danish lender Janske Bank will also release its third quarter figures.
German reinsurance giant Munich Re will hold a press meeting at 10:30 UK time on Monday.


Once again it’s just over a year since last time in the series. Having gone through a variety of one-offs and short-run stories, we rejoin Sonic the Comic at issue #175, for the final original story in the comic’s run – the 10-part adaptation of the Dreamcast launch title and fan-favourite that is Sonic Adventure. The world of Sonic Adventure being as different as it is to what had already been established through StC’s continuity, the writers decided to do their own unique take on the story. I’ll warn you at this point though – because this is the last story of StC, there’s some MAJOR spoilers ahead in tying up loose ends and just throwing a few curve balls at the reader. Consider yourselves warned, OK? Where else do you get spoiler warnings for material that’s nearly 2 decades old?
Right. Let’s get this thing rolling! Hit the jump to continue.
On this SEGA News Bits, Barry and George share their analysis of the rumor that Archie Sonic the Hedgehog comics are cancelled. How did this rumor spring up? Is there any validity to it? What could happen to the Sonic comic books should it happen? Give the video a watch to find out!
SEGA News Bits is a production of SEGAbits, covering all things SEGA and Sonic the Hedgehog. When we touch on Sonic stories, you’ll be seeing them here on Sonic Retro as well. If you enjoyed this episode of the SEGA News Bits, make sure to subscribe to our YouTube channel and never miss an episode!
Goodness, has it really been a year since the last time we visited the world of Sonic the Comic? Well, as time marches on, so does the progress in our quest, as we cover the penultimate game adaptation in the Fleetway series – Sonic 3D: Flickies’ Island (Or Sonic 3D: Blast, as the Yanks might know it, but as that name was only used in North America we won’t be seeing it again in this Euro-focused story!) It’s a short one this time, only covering 3 issues. Written at a time when games were beginning to become thin on the ground in the late 90s, the writers went in a slightly different direction with the story, as we’ll see. The island itself was featured in the comic for a few months afterwards as a base of operations for Dr Robotnik, but just as a location now available for the writers to use. But we’re getting ahead of ourselves. Let’s start back at the beginning, shall we? Hit the jump to continue – there is of course spoilers a-plenty ahead. Continue Reading
Archie Comics have sent out the latest comic solicitations, highlighting what SEGA and Sonic fans can expect from the publisher in May! With the epic Sonic and Mega Man crossover incoming, Capcom’s Mega Man books will be a must read for those who want to follow the event, meaning throughout the crossover we’ll be highlighting the Mega Man titles that fall under the Worlds Unite umbrella. After the break, check out the covers, synopsis, and story details direct from our friends at Archie. Continue Reading
So if you haven’t had the chance to read the Sonic and Mega Man Archie Comics cross-over yet, now’s a pretty good chance to buy a complete collection of all the issues if you don’t mind not having it physically. Humble Bundle and Archie are working together to sell a cheap bundle with all three volumes of the Worlds Collide cross-over, and also a bunch of other stuff like The Best of Archie, Afterlife With Archie, The Death of Archie, Archie: The Married Life, more Afterlife With Archie etc.
There are three different tiers you can choose from, each of which includes one volume with 4 issues. The first tier you can pay whatever you want for, for the second tier you need to pay more than the average and for the final tier you need to pay at least 15 bucks. Not a bad deal considering that that’s about half of what you’d normally pay for all of that, and that’s not including how much you’d pay for all of that other Archie stuff. And who wouldn’t want to read Archie Meets KISS? Also, as with all Humble Bundles you can decide how much of the money goes to charity and more comics will be included later on.
It’s also a pretty good way of catching up on all of that Worlds Collide stuff before they’re gonna mix in Rad Future Mega Man and Toilet Paper Sonic as well in its upcoming sequel.
Another year draws to a close, and as such it’s more than time for another visit to the wonderful world of Fleetway’sSonic the Comic. You may remember from last time that our heroes had just got the stolen Master Emerald back onto the Floating Island and blew up the Death Egg; and in the process of doing so they defeated a Metallix, who idly mentioned in chat about an “elite brotherhood” of the robots. All back up to speed now? It’s OK, you can go read part 6 again, I’ll wait.
Hello and welcome to my formal introduction to the Sonic Retro news page! My name is Barry, I’m an admin, writer and graphic designer for Sonic Retro sister site SEGAbits. Since our April 1st partnership, we’ve been making strides to bridge the sites, including bringing Sonic Retro writers on as SEGAbits writers. Now that I’m an official writer over here, consider the bridge built, but we still have improvements in the works.
To show that I have nothing to hide, I thought I’d be upfront about something. The letter to the left is my claim to fame in the Archie Sonic the Hedgehog comics, appearing in Sonic Super Special #15’s Sonic Grams. The issue itself was awful, featuring the worst art I have ever seen in a commercial comic book. But my contribution is arguably worse than the work of Many Hands. After gushing a bit too much over Archie’s Sonic Adventure adaptation, I noted my disapproval of a previous issue’s letter asking for the series to stop introducing new characters. It was then that I wrote what I’ll always regret writing: “I say the more characters, the better!”. Could I have unwittingly inspired Ken Penders to soldier ahead with his army of Knuckles clones? Was Mobius 25 Years Later my doing?
I should note that the original letter was edited down by Archie’s Sonic staff. I distinctly remember saying that I wanted more characters from the games, and I gave a specific shout out to the Chaotix. Still, the damage was done. So that’s my confession. At least they didn’t cut the part where I gave kudos to the awesome Patrick Spaziante.
Glad to be on the Sonic Retro writing staff and hopefully you all can forgive me.


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NEW YORK, March 31 (UPI) -- Black Sabbath's guitarist says the classic heavy metal band could reunite for Ozzfest 2004, Launch Radio Networks reported.
"As yet, we've not reached a settlement, but there is talk about it," Tony Iommi told Launch.
Rumors of a Black Sabbath reunion at the annual festival headlined by former Sabbath lead singer Ozzy Osbourne have been circulating for several weeks, fueled by word that Osbourne reportedly has joined forces with the band's bassist, Geezer Butler.
Rob Halford, singer of the recently-reunited Judas Priest, which is co-headlining this year's Ozzfest with Osbourne, welcomes the idea of a Black Sabbath reunion.
"It's brand new news to me, but I wouldn't be the least bit surprised if it happened," Halford told Launch.
"It just seems like, why wouldn't, why shouldn't it happen? But then, my God, can you imagine Judas Priest and Black Sabbath? It's just too mad to think about."


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Jill Kearney, author
A meth addict finds a gift to give her lonely brother. An alcoholic sneaks into his ex-wife’s house to use her shower and encounters his elderly dog. The misfits of a backwoods community confront with the abusive behavior of one of their neighbors. A teenage delinquent accidentally tells an elderly man just what he needs to hear. Realistic and emotional stories about rural poverty in America.

domain: sociology


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The developer recently added cross-save support to the online shooter, allowing players to transfer their progress from one platform to another.
Asked on Tuesday if the studio has plans to introduce cross-platform play, Bungie communications director David ‘Deej’ Dague told VGC that while it’s interested in “anything that would bring players together”, managing its resources is an ongoing challenge.
“While we don’t have any promises to make about new features that will come online in the future, I can assure you that there is always a lively conversation at Bungie – as there was for years before we arrived at even cross-save – about things that we could do that would be good for players, and that we want to find the time and resources to invest in and bring to fruition,” Dague said.
“We’re certainly keen to explore anything that would bring players together so that they can share their experiences.”
Dague continued: “In terms of the challenges, they’re always the same: it’s allocation of resources, it’s developer hours, it’s all of the things that we have to do.
“We make guided decisions as to where we want to invest our time: what sort of features do we think will be most useful to players? What things can we do to evolve the world of the game to keep people engaged and entertained?”
In recent years Microsoft, Nintendo and Sony have relaxed their policies towards connectivity with other platforms, with titles such as Fortnite, Rocket League and Minecraft enabling cross-play between all platforms.
Bungie ended its eight-year partnership with Activision earlier this year and acquired the publishing rights for Destiny, giving it full control over the future of the MMO shooter series.
And in October 2019, Bungie released Destiny’s free-to-play revamp New Light, its Shadowkeep expansion, and made Steam the game’s new PC home.
Starting with Shadowkeep, everything added to the game – from expansions to new seasons of content – is purchasable separately, enabling players to pick and choose the experiences they want.
Bungie has also pledged not to release any more platform exclusive or early access Destiny content, as had been the case on PS4 in the past.


I used Jacks D3 in the morning, although not familiar with this body....mine is only a D300, I soon got used to it. I was trying to get more DOF with it and was using apertures up to f/22.
The Pope HW97 V-Mach. Gary Cane Laminate stock. Leupold Competition 40 mag Mildot.
The Smiler. Walther LGU. WE Laminate stock. Leupold Competition.
The Dark Destroyer. TX200 MK3. Leupold Competition 40 mag.
Pro-Sport. Warren Edwards Blue Laminate stock. Bushy 8-32x40.


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Discover the world's most beneficial health and beauty oils with Gill Farrer-Halls' The Complete Guide to Essential Oils. It explains how they are used in aromatherapy and other well-being and beauty treatments.
It explains how to buy and store oils and reveals everything from scents to therapeutic properties. There is also a recipe that will help you fulfil the potential of the oil.
It covers floral oils, citrus oils, herbal oils, tree and wood oils, grasses, seeds and shrub oils, spice oils, resin and root oils and exotic oils.
The book looks lovely and appears to be well written with plenty of information. You asked me for a review but I didn't buy it for myself, it's for my niece who has a great interest in the subject. I'll give it to her at Easter, I'm sure she'll love it.


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This bizarre deep-water fish called the Barreleye has a transparent head and tubular eyes. The two spots above the fish’s mouth are not eyes, they are in fact olfactory organs called nares, which are analogous to human nostrils
Art Nouveau Tour of Barcelona. This is Casa Batllo, designed by Gaudi. Spain was not drawn into WW I and as such during that time, had prosperity. As as result, there are over 400 Art Nouveau structures in Barcelona.


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The passage of the Digital Millennium Copyright Act in 1998 has had plenty of consequences that its authors never envisioned, and ones which lawmakers periodically re-examine. That’s not necessarily shocking — the internet of 1998 and the internet of 2021 are very different, after all. But overzealous application of the DMCA has led to some surreal moments in recent years, such as the guitarist of the heavy metal band DragonForce being suspended by Twitch for the heinous offense of…playing his own band’s songs.
The latest such controversy involves a live performance by an artist streamed during BlizzConline, the online edition of BlizzCon, an annual event held by game publisher Blizzard Entertainment. The artist in question was Metallica, who played the in-person version of the event several years ago. The performance was broadcast on several Twitch channels, but — as EuroGamer reports — on Twitch Gaming, the sound of the band doing their thing quickly faded out and replaced by music that was decidedly not Metallica.
At The Verge, Chris Welch speculated that Blizzard secured music performance rights for its own channel, where Metallica’s set could be heard normally, but not for Twitch Gaming. It would certainly explain a lot.
Given Metallica’s lawsuit against Napster, it’s led to more than a few very public displays of schadenfreude. That said, the aforementioned lawsuit didn’t actually apply to the DMCA, which was passed 2 years earlier.
The Future of Music Coalition has a much longer thread exploring the issues at hand. But even if the overdubs weren’t some sort of manifestation of irony writ large, the clip of Metallica furiously headbanging while cheery video game music plays makes for wonderfully surreal viewing.
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