text:
- Academic Editor
Background: Alzheimer’s disease
(AD) is a chronic neurodegenerative brain disorder currently without satisfactory
therapeutic treatments. Triggering receptors expressed on a myeloid cells-2
(Trem2) gene mutation has been reported as a powerful AD risk factor
that induces Trem2 gene deletion aggravated microglia disfunction and
Alzheimer’s disease (AD) is a chronic neurodegenerative brain disorder currently
without satisfactory therapeutic alternatives [1, 2]. With an increasingly aged
population, the incidence of AD is increasing annually and the number of AD
patients is predicted to reach 130 million worldwide by 2050 [3, 4].
Microglia are resident immune cells of the central nervous system (CNS) and
serve the role of immune surveillance . In pathological situations, microglia
are activated by toxic A
A triggering receptor expressed on myeloid cells-2 (Trem2) is a cell
surface receptor protein of the immunoglobulin receptor superfamily that is
predominantly expressed on brain microglia . Recent studies have revealed
that Trem2 gene mutation is a powerful AD risk factor that slows down
the clearance of cell debris and toxic A
Danggui-Shaoyao-San (DSS) is a traditional Chinese medicine formula, first
recorded in Synopsis of Prescriptions of Golden Chamber written by Zhang Zhong-Jing during the Eastern Han Dynasty. DSS was originally
employed to treat gynecological diseases and was then found to have effects on
forgetfulness. More recently, medical records and clinical studies have suggested
that DSS may significantly improve the clinical symptoms of patients with
dementia [19, 20, 21]. Experimental animal studies have also demonstrated that DSS
alleviates cognitive impairment in AD models [22, 23, 24]. Furthermore, DSS may also
increase the expression of the M2 microglia polarization marker IL-4 and reduce
the level of the M1 microglia biomarker TNF-
Six herbs of Danggui-Shaoyao San, Angelica sinensis (Oliv.) Diels (Umbelliferae), Paeonia lactiflora Pall. (Paeoniaceae), Poria cocos (Schw.) Wolf (Polyporaceae), Atractylodes macrocephala Koidz. (Compositae), Ligusticum chuanxiong Hort. (Umbelliferae) and Alisma orientalis (Sam.) Juzep. (Alismataceae) were purchased from the Pharmacy Room of the First Affiliated Hospital of Guangzhou University of Chinese Medicine (Guangzhou, China). LPS (lipopolysaccharide) (Cat No. L2630, sigma, St. Louis, MO, USA), murine IL-4 (Cat No. 96-214-14-20, PeproTech, Suzhou, China), Arg1 (Cat No. 16001-1-AP, Proteintech Group, Wuhan, China), and antibodies against OX42 (Cat No. ab1211), Trem2 (Cat No. ab86491), iNOS (Cat No. ab15323), Arg1 and GAPDH (Cat No. ab8245) were purchased from Abcam (Cambridge, UK).
The extraction of DSS was performed in the Laboratory of Science and Technology Innovation Center, Guangzhou University of Chinese Medicine. Angelica sinensis (Oliv.), Paeonia lactiflora Pall, Poria cocos (Schw.) Wolf, Atractylodes macrocephala Koidz., Ligusticum chuanxiong Hort. and Alisma orientalis (Sam.) Juzep. were mixed with a ratio of 3:16:4:4:8:8. The herbs were soaked in distilled water (1:8, w/v) for 1 h and extracted for 1 h. After the filtrate was collected, distilled water was added (1:6, w/v) for a second extraction. The two filtrates were then mixed and concentrated to 1.28 g/mL DSS extract at 60 ℃.
Analysis of the main active components of the DSS water extract was performed using HPLC-MS/MS in a previous study . It was found that the extract included 78 main constituents. The concentration of albiflorin, paeoniflorin, benzoic acid, gallic acid, ferulic acid, Chuanxiong lactone Ⅰ, Chuanxiong lactone A were 1.76, 12.15, 0.68, 1.17, 0.29, 0.46 and 0.19 mg per gram extractum, and the highest content was paeoniflorin.
A total of 20 male C57BL/6 mice (seven months old) were purchased from the Model Animal Research Center of Nanjing University (Nanjing, China) and randomly divided into four groups (five mice/group), (1) normal group (0.9% saline, 10 mL/kg/day, i.g.), (2) high-dose DSS group (6.4 g/kg/day, i.g.), (3) mid-dose DSS group (4.8 g/kg/day, i.g.), (4) low-dose DSS group (3.2 g/kg/day, i.g.). The drug intervention period was continued for seven days. Serum samples were collected from the eyeball blood of mice 1 h after the last treatment administration. The serum samples were heat inactivated at 56 ℃ for 30 min, then divided and stored at –20 ℃ until use. The experiment was carried out in accordance with guidelines established by the National Institutes of Health of the United States for the care and use of laboratory animals and was approved by the Laboratory Animal Ethics Committee of the Guangzhou University of Chinese Medicine (Guangzhou, China).
BV2 microglia cells were obtained from the Science and Technology Innovation
Center of Guangzhou University of Chinese Medicine. The cell line has been authenticated based on morphology and functional expression, and mycoplasma testing has been done. Cells were cultured at 37
°C in an atmosphere of 5% CO
Antigen repair was performed with 0.01 M citrate buffer at 90 °C for 30 min. Subsequently, cells were saturated and permeabilized by 0.1% Triton X-100 (Solarbio, Beijing, China) and blocked in goat serum at room temperature. Samples were then incubated overnight at 4 °C with primary antibodies of anti-OX42, anti-iNOS, and anti-Arg1. They were then incubated with goat anti-mouse or goat anti-rabbit IgG at 37 °C for twenty minutes. Finally, the samples were stained with Alexa Fluor 488 anti-rabbit IgG or Alexa Fluor 594 anti-rabbit IgG at room temperature away from light for 1 h. Confocal microscopy (Serial No. 538623, Nikon 80i, Tokyo, Japan) was utilized to capture images. Positive cells were identified from three different perspectives in each sample.
The effect of DSS on the viability of BV2 cells was assessed by cell counting
kit-8 (CCK8). The cells were plated into 96-well plates at a density of 2
The capacity of BV2 cells to phagocytose A
BV2 cells were plated in six-well plates with fresh medium. Trem2 over-expression lentivirus, Trem2 siRNA, and non-targeting siRNA (control vector) transfection were performed respectively according to the manufacturer’s instructions by Lipofectamine 2000 reagent (Lot No. 2744064, Invitrogen, Carlsbad, CA, USA). BV2 cells were cultured in serum-free medium for 8 h then treated with different concentrations of DSS drug-containing serum (0, 3.2, 4.8, and 6.4 g/Kg/d) for 24 h.
The protein of BV2 cells was obtained by lysis with RIPA buffer. Bicinchoninic acid (BCA) assay was employed to quantify the protein concentration. Samples were separated by SDS–polyacrylamide gel electrophoresis (SDS–PAGE), transferred to polyvinylidene difluoride (PVDF) membranes (Millipore, Billerica, MA, USA), and blocked by 5% BSA for 1.5 h at room temperature. The membranes were then incubated overnight at 4 °C with the Trem2, Arg1, and iNOS antibodies specific for target proteins, and then incubated with the secondary antibodies for 1 h at 37 °C. Detection was performed using the Gel Imaging System (Serial No. 721BR19506, Bio-Rad, Hercules, CA, USA) and quantified by Image Lab 5.2.1 software (Bio-Rad, Hercules, CA, USA).
TRIzol reagent (Lot No. 93289, Sigma, St. Louis, MO, USA) was applied to extract total RNA from
BV2 cells with different treatments in each group according to
the instruction manual. The ratio of OD260 to OD280 of total RNA was measured by
microspectrophotometer and the purity and concentration of RNA were calculated.
Samples with a ratio between 1.8–2.0 met experimental requirements. cDNA
templates were prepared by performing reverse transcription reactions according
to the reverse transcription protocol of PrimeScript™ RT Master
Mix (Lot No. RR036B, Takara, Beijing, China). Following
|Gene||Forward sequence||Reverse sequence||Size|
All data were analyzed by the software package Statistic Package for Social
Science (SPSS, v.26.0, Armonk, NY, USA) and data were expressed as mean
BV2 cells were treated either with LPS at a concentration of 100 ng/mL or IL-4 at a concentration of 20 ng/mL in DMEM for 24 h to induce either the M1 or M2 phenotype. As shown in Fig. 1A, the results of immunofluorescence double-labeling revealed that activated BV2 microglia cells with large and round cellular bodies, disappeared cellular projections and amoeboid shape were observed after either LPS or IL-4 treatment. LPS up-regulated the M1 microglia biomarker iNOS, which indicated an alteration of microglia polarization toward M1 status. While IL-4 up-regulated the M2 microglia polarization marker Arg1, which promoted microglia polarization toward a M2 phenotype (Fig. 1B). Moreover, LPS enhanced the protein expression of iNOS and decreased the expression of Trem2 in the M1 polarization state. In contrast, IL-4 remarkably increased the protein expression of Arg1 and Trem2 in the M2 polarization state (Fig. 1C,D). Taken together, Trem2 was highly expressed in the M2 polarization phenotype and poorly expressed in the M1 polarization phenotype.
Trem2 expression in different polarization states of
BV2 cells. (A,B) Cell morphology changes and immunofluorescence of iNOS
(red)/Arg1 (red) and double immunofluorescence labeling with OX-42
(green). (C,D) Western blot analysis of iNOS, Arg1, and Trem2
protein expression in control, LPS (100 ng/mL), and the IL-4 (20 ng/mL) group.
GAPDH served as the loading control. Scale bar: 10
To further confirm the effect of Trem2 on BV2 microglia activation, the
Trem2 over-expression lentiviral vector and Trem2 siRNA were
used to transfect BV2 cells. The expression of microglia activation marker
proteins was then evaluated by Western blot. Results showed that Trem2
over-expression significantly reduced the protein expression level of iNOS,
whereas increased expression of Arg1 in BV2 cells (Fig. 2A,B). In
contrast, Trem2 silencing obviously enhanced iNOS expression and
inhibited Arg1 production. Results further revealed that Trem2
induced a shift of M1 microglia towards the M2 phenotype (Fig. 2C,D). The effect
of Trem2 on the A
Effect of Trem2 on microglia polarization and
To investigate the effect of DSS on BV2 cell viability, BV2 cells were cultured with different concentrations of DSS-containing serum (3.2 g/kg/d, 4.8 g/kg/d, and 6.4 g/kg/d) for different durations (12 h, 24 h and 48 h). As shown in Fig. 3A, compared with the normal group, cell viability significantly increased in the low, medium, and high dose DSS-containing serum groups. These findings showed that DSS-containing serum increased BV2 cell viability in a dose- and time-dependent manner.
DSS enhanced cell viability in a dose-dependent manner and
increased Trem2 expression, which promoted the conversion of microglial
cells to the M2 state. (A) Cell viability was detected by CCK8 Assay. (B,C)
Western blot analysis of Trem2 in control and DSS treated groups.
GAPDH served as control. (D,E) mRNA level of the M2 biomarker
Arg1 and IL-10 treated in four different groups for 48 h using
RT-qPCR technology. *p
To verify the effect of DSS on Trem2 expression in BV2 cells,
Trem2 protein expression levels were examined in BV2 cells treated with
different concentrations of DSS-containing serum for 12 h, 24 h, and 48 h. As
shown in Fig. 3B,C, the results of Western blot showed that DSS enhanced
Trem2 expression in BV2 cells and these effects were dose and time
dependent. Next, at the 48 h time point, the effect of DSS on the M2-associated
mRNA expression levels of Arg1 and IL-10 were determined and it
was found that DSS-containing serum dramatically increased the expression of
Arg1 and IL-10 mRNA (Fig. 3D,E). Alternatively, it was observed
that DSS-containing serum significantly reduced the M1-associated mRNA levels of
iNOS and TNF-
DSS enhances the phagocytosis capacity of microglial
cells in a dose-dependent manner. (A) Fluorescence intensity of cells was
measured by flow cytometry to determine the phagocytosis capacity of A
The effect of DSS on the A
Different concentrations of DSS-containing serum were used to treat BV2 cells
transfected with siRNA-Trem2 and it was found that DSS increases the
DSS did not recover A
Trem2 silencing inhibited DSS-mediated microglia
polarization toward M2 phenotype and A
Microglia are the main endogenous immune cells of the CNS. Microglia not only
exert a classic role as “scavengers” for the maintenance and restoration of the
CNS, but also play a key role in neuron functioning such as cell migration,
apoptosis, survival, and synaptic plasticity. The effects of microglia in various
neurodegenerative diseases including AD have recently drawn increasing attention
[27, 28]. Trem2 is a transmembrane protein selectively expressed on
microglia in the brain, which enables microglial responses including
proliferation, survival, clustering, and phagocytosis through sustaining cellular
energetic and biosynthetic metabolism during AD [28, 29, 30]. An analysis of genetic
variability revealed that genetic variants of Trem2 were associated with
a threefold increase in the risk of developing AD and that the complete loss of
Trem2 resulted in an early-onset dementia [31, 32]. Furthermore, recent
studies in AD mouse models have confirmed that the loss of Trem2
function caused classic AD pathology and suggested an important role of
Trem2 in microglia function [33, 34, 35]. In the current study, it was found
that Trem2 had positive effects on improving a shift of M1 microglia
towards an M2 phenotype. Moreover, it was shown that Trem2 enhanced the
The underlying molecular mechanisms of Trem2 displayed
a positive effect on anti-inflammatory M2 polarization of microglia and
DSS is a classical Chinese complex prescription for the treatment of AD. Recent
studies have drawn attention to the fact that DSS exhibits anti-inflammatory and
antioxidant activities and prevented cell apoptosis in the hippocampus [36, 37, 38].
Furthermore, DSS administration was shown to ameliorate a scopolamine-induced
decrease in the levels of acetylcholine in AD model mice . Importantly, DSS
treatment has been reported to inhibit neuroinflammation in LPS-induced BV-2
microglia cells . However, the specific mechanisms of action of DSS on
microglia in AD have not yet been completely elucidated. In this study, it was
observed that DSS elevated the viability of BV2 cells and Trem2 protein
expression in a dose and time dependent manner. Furthermore, DSS remarkably
enhanced the expression of M2 microglia phenotype markers Arg1 and
IL-10 mRNA, while reducing the expression levels of M1 microglia
phenotype markers iNOS and TNF-
AD is the most prevalent neurodegenerative disorder leading to severe cognitive
and functional deterioration in an aged population . The presence of
However, this study had some limitations. First, DSS prevented the development
In conclusion, this study confirmed that DSS administration promotes the
clearance of A
The datasets used and analyzed during the current study are available from the corresponding author on reasonable request.
QW, XC and CY designed, supervised the study, and supported funding acquisition. GCC, MMH, YC, and CY per-formed the experiment. YLL, ML and LW analyzed the data. GCC wrote the manuscript, CW, YXH and JHN acquired the data and revised the manuscript. YSM and LY constructed the figures and revised the manuscript. LY, XC, and CY finalized the paper. All authors contributed to editorial changes in the manuscript. All authors read and approved the final manuscript.
The experiment was approved by the Laboratory Animal Ethics Committee of Guangzhou University of Chinese Medicine (approval ID: 20200721005) and performed in accordance with guiding principles of the United States National Institutes of Health for the care and use of laboratory animals.
This work was funded by National Natural Science Foundation of China (No. 81704131 and No. 81904168), Key laboratory project of colleges and universities in Guangdong province (No. 2019KSYS005), Guangdong province science and technology plan international cooperation project (No. 2020A0505100052).
The authors declare no conflict of interest.
Publisher’s Note: IMR Press stays neutral with regard to jurisdictional claims in published maps and institutional affiliations.


text:
Readers of my blog, One Foot Out the Door, know my favorite travel mode is my own two feet. But there’s a certain kind of hike that I love more than any other: the circuit trek. Although I’ve enjoyed many out-and-back and one-way trails, there’s something uniquely satisfying about a complete loop.
Latin America Regional Specialist Tanya Rao just returned from our "Argentinian Patagonia: Hiking Glaciers and Exploring Lakes" trip with some great photos that we just had to share!
On the Tour du Mont Blanc, hikers journey through Italy, Switzerland, and France on their quest to conquer the Mont Blanc massif, with its spine-tingling panoramas and quaint Alpine villages. Julia Hendershot, travel expert and adventure coordinator for MTS’s Europe programs, explored the scenic grandeur of the Swiss Alps on her recent tour of Mont Blanc. Read about some of the most defining moments of the trip.
Asia adventure specialist Corinne Edwards takes us on an insider journey through Nepal's scenic Himalayan landscape to Everest Base Camp via the beautiful Dudh Kosi Gorge—one of the most stunning hikes on the planet—and the important Tengboche monastery. With epic views of snow-capped giant Mount Everest on the way, this is one of the world's ultimate adventures!
We're delighted to share the travel adventures of Asia Program Director Julie McCormack, whose 12-day journey through Iran was originally published in the Orinda News. From its mind-boggling history and incredible antiquities, to its warm and welcoming people, this insider story goes deep into the fabric of a fascinating nation.

domain: geography


text:
Antonio Brown continues to be a star in Pittsburgh, and now he has a favorable matchup against Green Bay's secondary. Bill Bender previews the Steelers-Packers matchup.
Fantasy Source recaps all the Week 12 fantasy football action, including Josh Gordon's career day against the Steelers.
Can either Tony Romo or Eli Manning lead a fantasy championship run? Bill Bender breaks it down -- and picks the right QB -- in his Week 12 Rankings.
Before delivering the latest Week 11 notes, Ladd Biro guides you through a fantasy owner's dream (or nightmare).
Before getting you ready for Week 10, Ladd Biro unveils his midseason "perfect draft." You better believe Peyton Manning is on it.
Aaron Rodgers' injury leaves fantasy owners in a tough spot. But as Ben Valentine explains, there are some interesting replacement options on the waiver wire.
Alshon Jeffery is one of the game's up-and-coming playmakers. Which other receivers can owners trust through the bye weeks? Bill Bender takes a closer look in the Week 6 rankings.
- Player Updates
AFC EastNFC East

domain: sports


text:
UTA Signs Barbra Streisand; Famed Singer to Direct More 11 weeks ago
UTA has signed Barbra Streisand as a film client, representing her as an actress, director and producer. The agency also will represent her...
By Lucas Shaw
"A Chorus Line" runs at London Palladium from Feb. 2 to June 29
Marvin Hamlisch composed the music to "A Chorus Line," "Sweet Smell of Success" and "The Goodbye Girl"
Barbra Streisand says that "The Way We Were" composer was a musical genius
Marvin Hamlisch wrote the music for "The Sting," "Sophie's Choice" and the Broadway hit "A Chorus Line"
Richard Linklater’s third peek into the love story of the couple played by Julie Delpy and Ethan Hawke celebrates romance, compromise, disillusionment and the glory of conversation

domain: artistic


text:
Porcelain & Pottery Shops Listed by Most New Items
Antiques and Collectibles from China, Japan and around the World
Welcome to our shop.
please. For other hours, please use
Genuine Elegance! Rare Authentic Antique & Vintage Jewelry ~ Wearable Investments!
Fine Art Nouveau, Art Deco and Arts & Crafts Porcelain and Pottery
Free Shipping in the US!! 50% Off Stated International Shipping!! All Reasonable Offers Considered!
Fill your home with Heritage.
Hand-selected antiques direct from Europe
Antiques, Vintage & Modern Art from around the Globe
Promo: All shipments to the United States will be charged a flat rate of $49.99.
Glass, porcelain and silver from the 16th to the 20th century from an established family business
This is just a sample of our stock. Please contact us for sales tax discounts for all non-EU residents.
Your Destination for Fine Art, Estate Jewelry & Antiques
Fine Art, Estate Jewelry & Antiques - See Our Jewelry VIDEOS - Super Flexible LAYAWAY - $1500 item for 150 a month!
Antique & Vintage glass, pottery, textiles, books, jewelry and porcelain at very reasonable prices!
New items added daily at reasonable prices for your collections and home decor.
Eclectic Antiques Art And Collectibles -- From French To Mid Century Modern
Welcome to Royal Pelican Antiques Have Fun Shopping
The most beautiful items highly prized rare treasures
Thank you for viewing our beautiful Antiques Art & collectables
Port Saint Joe
A Little Bit of This, A Little Bit of That, Vintage Collectibles and Jewelry
Make Your Own Sale - Make An Offer!
A fine, fun, and funky assortment for discerning collectors.
SHIPPING always combined & LAYAWAYS always welcome on the fine, the fun, and the funky.
Charlotte's Favorite Place
Beautiful & Timeless Art, Antique & Jewelry. . classically chic with a modern attitude
We carry the valuable and whimsical at affordable prices
Treasures' From Kansas to Your Home!
Wide selection of Antiques, Collectibles, Fine Art, Clocks and Furniture
50% sale on numerous items in our lanes! Check out our selection of newly added items!
Specializing in Scottish and Victorian Jewelry, China, Silver and Baby Items.
Next Show Scottish Festival. S. California End of May. Inquire* No Reproductions - Authentic! *Ask about Layaway on over $100
Quality, Service and Integrity for over 47 years!
Layaways Available, Just Ask!
Glassware, Dinnerware, and Unique Small Treasures
Welcome Spring! Please explore the many items that are reduced in price!
Antique Treasures from the Texas Hill Country
Welcome to my shop featuring antique dolls and assorted unusual antiques!
Enjoying the hunt for the best examples of antiques for your home for over 35 years.
Enchanting Antique Dolls and Romantic Wares from Times Past
Delicious antique dolls, miniatures and romantic wares. We provide flexible layaway plans & offers are welcomed!
Renew your surroundings with unique items of all kinds
Renew offers items that may be unique, new or slightly used and considered vintage or antique
Let me know what you're looking for!
Eclectic mix of fine porcelain and a little bit of everything else.
Fine antiques, furniture, clocks,china, silver, vintage pieces, dolls, toys & other children's items
Welcome to Bluebonnet Hill Estates & Antiques. We have items from fine estates and from travels across the country.
Antique English pottery and porcelain at sensible prices
Exciting new items arriving every month, if you are looking for a specific pattern we can help you find it......
Everyone collects something and we have something for you.
We Now Accept Layaway!!
as I am not always available
Specialize In Victorian Staffordshire Dogs, Antique Photographs, And Fine Arti
Fine Art Sale ~ Ends June 1
Your Destination for Fine Animal Theme Antiques and More
Animal Theme Antiques and More. A Gem of an Antique Store ! Antique Oyster Plate Sale.
Antique Beauty – Beauty at your home
Ancient beauty in a modern interior
18th and 19th Century English Porcelain, Transferware, Pearlware and Other Interesting Pottery
We sell Early English Porcelain, Staffordshire, and Other Appropriate Ceramics.
Antiques, Vintage, Collectibles. Vintage jewelry and treasures to make your house a home.
Welcome to my shop!
We offer Vintage Postcards, Chinese Antiques, Autographs, Graphics and more. WORLD WIDE SHIPPING!!
Welcome! Your Shop for perfect Gifts, Vintage Collectibles and Unique Antiques. 2500+ Unique Objects to choose from.
Wien A - 1230
Antiques, Collectables, Jewelry and Vintage Clothing
All Reasonable Offers Accepted!
Shop For Unique Memories And Amazing Primitives From A Time Gone By
We're Dedicated To Quality And Variety And So Glad You Chose To Take A Closer Look! Welcome!
Providing antiques with integrity, service, and value since 1930.
Unique vintage, antique items, jade and Asian porcelain
Fine antique vintage jewelry, Asian artifacts and porcelain collections
A selection of fine collectibles ranging from antiques to vintage
Welcome to my shop
ON L6T 1W2
MB R2Y 1N5
19th & 20th Century Antiques, Collectibles and Decorative Arts
Providing quality items for you to cherish and enjoy.
Please enjoy your shopping experience. Layaway plan is available and offers are always considered.


text:
, vice mayor of Luoyang, Chen Shuxin and other leaders attended the press conference.
May 26th, 2016 Luoyang through Silicon Valley innovation contest press conference held ceremoniously in Luoyang National University Science Park at the same time, 2016 Luoyang through Silicon Valley innovation and entrepreneurship contest the semi-finals officially started, 104 entrepreneurial teams and companies from all over the country in the field of competition. Headlines as a collaborative media to attend the meeting.
my website address: fzpic, in order to avoid advertising suspects, I will be the last subtitle of the site by asterisk.
but in order to express and I’m not talking nonsense, I tell you my website name: "Chinese free recruitment network" people can go to use sh419 Search.
first website advertising, we must first understand their own, one even what they do are not clear, then don’t talk about the other!The nature of
2. your target group is what?
The characteristics of these
3. of your target consumer group?
4. they can accept advertising forms and ads like that?
now there are many kinds of forms of advertising, we should according to the points I mentioned above to choose their own advertising.
here note, when we do GGAD, don’t cheat, cheat his check is very strict, which is why his price is high, and there are many reasons why people do not, but no skill, remember to put some cheap GGAD advertisers to shield, or you flow go, but the effect is not!
brand promotion with these strokes, July activities set off 500-1000 yuan
subsequently, 2016 Luoyang through the Silicon Valley innovation and entrepreneurship competition program release. It is understood that the contest from February to July, divided into preliminaries, semi-finals and the final round of competition. At present, the preliminary link has ended, there are 104 companies entrepreneurial team and talent shows itself from more than 500 domestic and foreign teams in. The semi-finals will be held at the National University of science and Technology Park in Luoyang in from May 26th to 27th, and 24 high-quality items will be selected to enter the final link. Finals will be held in June 15th, and ultimately will be selected enterprise group, team group one or two, three prize, to share the total bonus of up to 2 million 700 thousand yuan. In addition, the competition will also be selected from 5 to 10 projects, sent to the United States, Silicon Valley, and the world’s top business team learning exchanges.
it is understood that the contest sponsored by the Luoyang municipal government, Luoyang City Committee, the Luoyang Municipal Science and Technology Bureau, Luoyang municipal office personnel, Jianxi district government, Luoyang National University Science Park, iFLYTEK, Henan Limited by Share Ltd Blackstone public record Co. Ltd., Henan Chong Ka Space Network Technology Co. Ltd. and other contractors. The contest is committed to help Luoyang to further create a national demonstration base of Small and micro businesses hit City, Luoyang to build the local brand innovation and entrepreneurship competition, the further introduction of international capital, talent, technology, project management resources, the success of Luoyang to the international stage of innovation and entrepreneurship.
conference site, the origin of capital, pine capital, black butterfly capital, Hong Thai fund and other more than 20 well-known representatives of domestic investors to visit the scene, respectively, for innovation and entrepreneurship were carried out a wonderful keynote speech.

domain: economics


text:
Written by Martin Gregorie
Mention the word “triathlon” and most people have the same usual response, “Oh that sounds hard” or “I could never do that”. It wasn’t that long ago that I felt that way myself.
Each step that is taken in a triathlon is a challenge, yet not all triathlons are created equal. True they all consist of swimming, biking, and running-always in that order but the distances vary. People assume that that all triathlons mean the Ironman, which is an event that while fascinating is only reserved for the truly dedicated or insane.
My journey into multi-sport triathlon started in 2013 with indoor triathlons or “try a tri” which are 15-minute timed segments of swimming, spin biking and tread mill or track running. Initially I did these events as a way to beat the winter blues and the treadmill just seemed to get boring. In my mind I thought that it was a safe environment to try something different and if I could get out of the pool alive, that alone would be a victory.
I think one of the reasons I was hesitant to attempt an outdoor triathlon initially was that in my having Cerebral Palsy, running was challenge enough. To add two other disciplines BEFORE running just seemed like some sort of self inflicted torture
Swimming seems to be the biggest obstacle for anyone who is considering doing a triathlon. It was no different for me. . Oddly, while my legs allow me to run, they are rendered useless in the water. My ability to swim rests entirely on my upper body. Still, like anything I have to work at it.
As I became more comfortable in the water, the events seemed to become more inviting. Soon the thoughts of the next event consumed my mind. Like my running 5k races before, I started to look at triathlon as a way to prove something to not only myself, but to other people. . For me it was to prove that at the age of 39 my body was getting better, and not worse. That Cerebral Palsy was part of my life but cannot limit what I can accomplish
Doing a triathlon event, just that one time, can get you sucked in and keep you coming back and trying to beat your performance from the previous event.
2014 was my first true “season” of triathlon. I even went as far as to register as a member of USAT as a para-triathlete. This was a big step for me. Registering as a para athlete meant admitting to myself that I have a disability. This was tough to take, but it was the best thing I could have ever done. Not only did it make my race day experience more enjoyable, it gave me a sense of pride knowing that my being out on the course among all the other fantastic athletes, I was representing the thousands like me who dare to dream, participate and compete.
As a para-athlete, I am given certain race day accommodations. These aren't to make my race easier, but to level the playing field and make my race experience as safe as possible for myself and other competitors. In registering for a triathlon, I ask for just three things from Score This race officials. Assistance with my wetsuit and a chair in transition, and perhaps some assistance getting onto and off my bike. The Score This team was wonderful at making my race day experiences enjoyable and memorable at the same time.
Starting with the ECC Kats triathlon, it was all about participating and finishing or so I thought. Soon after seeing the results I found myself wanting more, knowing I could do that much better if I worked at it. So it was on to PAIN in the Alleghenies and a bike course that lives up to its name. Then it was the Summer Sizzler and finally the Finger Lakes Tri. Each event filled with its own unique set of challenges.
The truth is you will never know what your body is capable of unless you begin to demand more from it. Sure I set goals for myself. I wanted so badly to finish a Sprint distance in less than 2 hours. I fell short this year but every event I learned something that will eventually get me there
Physically challenged, old, or even over weight, if you can try, you can compete. Taking the first step toward your finish line is up to you. I promise you this. If you take that step, it won’t be long before you will discover what possible can look like.
Please take a moment to check out Marty's Charity Footsteps of WNY: http://www.footstepsofwny.org/
Marrin Gregoire is the first paratriathlete in the history of the Score This!!! Multisport Series to receive a series award for his accompliments in the 2014 series. CHeck out the Score This!!! Multisport Series here: http://score-this.com/st-multisport-series

domain: hobby


text:
If there have been any benefits to lockdown, one of them has been the opportunity to try out and dust off our neglected creative projects; the zombie sitcom, the UK garage jazz fusion album or maybe just the odd watercolour.
That's why we brought together two of the brightest creative minds in film and fashion, actor Josh O'Connor and designer Jonathan Anderson, at Esquire Townhouse with Breitling to hear how they spent lockdown and how they approach the creative process. We'll also be considering how their pro-level techniques might help us amateurs up our own game.
Josh O’Connor is one of the hottest young acting talents around right now and his brilliant portrayal of Prince Charles in The Crown looks set to accelerate this status. He takes an unusual and meticulous approach to his roles, which involves creating scrap books and using physical props of the characters he plays.
For the brilliant God’s Own Country, he worked as a farm labourer in preparation – and even during – filming, in an effort to fully get under the skin of his character.
It’s from watching this film that his friendship and creative partnership with fashion designer Jonathan Anderson began; Anderson knew straight away he wanted to cast O’Connor in the Loewe campaign, for whom he's been Creative Director since 2010.
He also has his own JW Anderson label, for which he won both menswear and womenswear designer of the year in 2015, famous for his innovation, experimentation and wide range of influences, of which art plays a central role.
Make sure you check out the rest of the Townhouse 2020 line-up here.
Like this article? Sign up to our newsletter to get more articles like this delivered straight to your inbox
Need some positivity right now? Subscribe to Esquire now for a hit of style, fitness, culture and advice from the experts


Biafra: Residents of Aba, Owerri, Enugu comply with sit-at-home
Markets including the popular Ariara main market in Aba were on total lockdown.
Lagos APC Primaries: Fear, Tension in Oshodi, Shogunle as rival group kills NURTW boss
Mr. Bello, popularly known as Hamburger, was shot dead on Monday.
Biafra Day: Police warn against intimidation of citizens, provide distress numbers
Biafra groups issued a sit-at-home directive to the people of the South-East and South-South regions.
Mixed reactions trail Lagos APC councillorship primaries
The elections were postponed in some parts of the state.
Notore, Kaduna govt partner to harness agribusiness opportunities
“We have a genuine desire and interest in ensuring that we achieve food security in Nigeria.”
Why my administration is focused on building bridges, flyovers – Amosun
The governor said his administration plans to ensure the completion of all ongoing projects by 2019.
Akeredolu backs restructuring, urges improved democratic values in Nigeria
The governor appreciated the people of the state for their support for his government.
LASTMA dismisses 20 officials for corrupt practices
Fifteen other officials were given warning letters.
How to stop building collapse in Lagos – Commissioner
At least two people died when a building collapsed on Monday.
I will name my successor in May 2018, will run for Senate – Ajimobi
The governor also said he had identified five possible successors – Ajimobi
Two dead, 14 rescued from collapsed Lagos building
Three buildings have collapsed in the last month in Lagos.
Bauchi delegation arrives China for $27.5 billion deal – Official
The Bauchi governor also highlighted the successes of his administration.
Anglican Church dissociates self from IPOB, MASSOB sit-at-home protest
IPOB and MASSOB urged Igbos to sit at home on May 30.
Despite court order, Nnamdi Kanu addresses pro-Biafra crowd
The IPOB leader was granted bail in April on 12 conditions.
Ramadan: Governor warns traders against profiteering
Governor Sani Bello also called on well-to-do in the society to extend their goodwill to the less privileged.
WHO partners media on humanitarian crisis in Nigeria’s North-East
“The role of the media in setting agenda for the public and policy makers cannot be more appropriate in the ongoing crisis in the North East.
Ekweremadu, Gov. Umahi speak on Biafra sit-at-home order
“The deputy senate president is fighting marginalisation of the Igbos at the federal level,” the governor said.
Continuous voter registration ongoing in all Borno local govts – INEC
The exercise was initially delayed in five Borno LGAs.
Lagos holds the seed of Nigeria of our dreams – Osinbajo
The Acting President joined sitting and former governors to celebrate Lagos at 50.
Despite being among Nigeria’s richest states, Akwa Ibom governor says state lacks funds for LG elections
“The prevailing economic situation is not conducive for us to conduct local government elections.”
Civic group wants church management prosecuted for building collapse
The building collapse caused the death of at least 26 people.
NAHCON approves N1.5 million as Hajj fare for Kaduna pilgrims
All pilgrims were to receive $800 as Basic Travelling Allowance.
JUST IN: Security operatives take over Lagos APC office as violence erupts during primaries
Angry party members protested the announcement of candidates endorsed by the party leadership.


text:
By 2050, we will have to feed nearly 10 billion people. With the constant impact of current food manufacturing on the climate and expanding populations, changes have to be made.
by Andy Kusumo
To assure our food future is sustainable, food production systems must increasingly consider the impacts made by our food choices on our physical health and the health of our planet. Simply explaining the benefits of changing our diets is not enough. We need a wider set of interventions to accelerate the uptake.
Today, it is increasingly acknowledged that our meat addiction is literally ‘costing the Earth’. In the short term, the biggest lever we have to improve the health of our bodies and the environment is to eat less meat, and particularly from intensively reared livestock.
That is why healthy new proteins with much lower environmental impact are vital if we are going to assure a sustainable food future for us all. This is the next green revolution, and one that Quorn® has been quietly pioneering since the brand’s inception in 1964. The plant-based food industry is on the rise globally as more people are understanding the impact of a meat-heavy diet on health and our environment. Specifically, the negative impact of animal agriculture on global sustainability.
A study in 2010 estimated water consumption in beef production at 15,415 liters per kilogram, a far cry from the 322 liters needed to grow one kilogram of vegetables. The International Agency for Research on Cancer (IARC), the cancer agency of the World Health Organization, classifies red meat, particularly when processed, a carcinogen. Studies supporting plant-focused diets are pouring in, with a recent report from the EAT-Lancet Commission which suggested that a predominantly plant-based diet with reduced meat consumption can mitigate climate change and confer health benefits, such as a lowered risk of heart disease.1
Feeding an Ever-growing Population
An acceleration of both over- and undernutrition within global populations, where current estimates place nearly one million starving people on the planet, and twice that number who are obese. Recent estimates suggest that 20 percent of all global disease is diet-related and therefore wholly preventable.
We can choose which to feed, be it people, animals or cars. Our food production capabilities are finite, and we cannot keep trying to produce more food, feed and fuel crops without devastating consequences. Furthermore, without intervention, we will continue to waste around a third of the food we produce, meaning that approximately 10 percent of the global greenhouse gas (GHG) emissions in developed economies comes from food that was grown but never eaten.
Two Interconnected Challenges: The Health of Human Beings and The Planet that Sustains Us
From a health perspective, we know that poor diets are creating major issues around heart disease, cancer and diabetes, to name a few, which affects the quality of millions of lives and also puts incredible stress on public health systems. The sustainability crisis, on the other hand, has had a growing place in the spotlight, with the need for action only becoming more urgent.
So how exactly are our two great challenges interconnected? The answer is simple: by what we eat. A staggering 14.5 percent of GHG emissions are coming from the livestock supply chain, leading the United Nations (UN) to identify cutting down on meat as the biggest single change individuals can make to address climate change. It’s not surprising to see both these issues embedded in the UN Sustainable Development Goals (SDGs), to which alternative protein options like Quorn® can make a significant contribution.
Food Science and Technology: A Game Changer
Just like how renewable energy was born to complement traditional sources of energy, the meat-free protein sector will only grow from strength to strength, complementing meat as a traditional protein source.
To put things into perspective on how quickly and massively this industry is growing, the alternative meat market is projected to reach $140 billion globally over the next decade, according to a team of Barclays analysts spanning the agriculture, food and restaurant industries. That rapid pace of growth implies the animal-free industry could capture about 10 percent of the $1.4 trillion global meat industry. With the meat-free movement in full swing today, many plant-based meats have sprouted up in recent years with hundreds of millions of dollars in funding pumped into R&D in alternative protein food technology.
Around the world, we’re seeing major meat producers and consumer goods giants investing in meat alternatives. Even fast food chains have started jumping on the alternative protein bandwagon. With some of the world’s biggest grocers and restaurants ramping up their meatless offerings, it has probably never been a more popular time to try a greener meat. According to a recent survey by Ipsos Public Affairs U.S. across 29 countries, respondents in Asian giants, China (73%) and India (63%), were most willing to try plant-based products, marking Asia as a massive market with long-term growth potential for the alternative protein space.
The Way Forward
With the rise of mindful consumers around the world, and people becoming more aware about how their consumption habits impact health and the environment, the meat-free movement will only continue to scale globally. Transparency and commitment to rigorous and scientifically backed research will be key to ensuring the success of the meat alternative industry. This is crucial, given that meat-free brands are now facing increasing scrutiny by regulators worldwide, with the safety concerns due to use of GMO or carcinogenic ingredients, as well as aggressive marketing techniques. Quorn® remains committed to transparency and its more than 20-year clinical nutrition research program and its main ingredient, Mycoprotein, is GMO-free and a whole food, sustainably sourced from farm to fork.
Long before today’s Silicon Valley firms even caught the wind of the meat-free movement, Quorn® has been conducting rigorous research and development to establish Mycoprotein as a nutritious protein source with multiple health benefits, a low environmental impact, and versatility bring dishes in their authentic flavors across a diversity of cultures.
Mycoprotein belongs to food class that Asian consumers have already been consuming for a long time, for example, bread, mushroom, tempeh, and soy sauce. Quorn® ‘s Mycoprotein products continue to rise in popularity across the world, due to their nutritional profile, potentials to prevent top health issues we face today (cholesterol, obesity, diabetes), as well as stimulate muscle growth more effectively than milk protein. Quorn® will continue to drive the future of food and empower consumers worldwide to make sustainable choices. [APBN]
- Chan, Jessica (2019) Plant it forward: Is plant-based meat a fad or our future? (online), [Retrieved from]: https://www.businesstimes.com.sg
About the Author
Director, Science & Technology, Quorn®

domain: food


Lamar Miller rushed 19 times for 178 yards and a touchdown in the Dolphins' Week 17 loss to the Jets.
Miller temporarily broke this one open with a highlight-reel 97-yard touchdown run in the third quarter. The run was the longest in Dolphins history, and one of the longest of all time. After disappointing fantasy owners across the board in 2013, Miller bounced back with a fury in a classic post-hype breakout year. He rang up 1,099 yards on 216 carries, averaging 5.09 YPC with 38 receptions and scoring nine all-purpose touchdowns. The Dolphins' coaching staff doesn't seem to view Miller as a true workhorse back, consistently holding him under 20 carries, but he proved an outstanding match for first-year OC Bill Lazor's space-creating run scheme. Miller should return in 2015 as Miami's clear feature back. He turns 24 in March and is owed a cheap base salary entering his contract year. We suspect Miller will be a third-round pick in 2015 re-draft leagues. He's a borderline RB1 in Dynasty.
Kris Durham caught zero passes on two targets in Sunday's Week 17 loss to the Colts.
Durham played in four games for the Titans this season, catching six passes for 54 yards. The impending free agent will keep getting NFL sniffs because he's 6-foot-6, but Durham is flat-out terrible and drop prone.
Knile Davis rushed nine times for 23 yards in Sunday's Week 17 win over the Chargers.
Davis got more playing time this week with Jamaal Charles not fully healthy. He finishes with 134 carries, 463 yards (3.46 YPC) and seven total touchdowns in 16 games (one start). Despite showing starting ability behind Charles, Davis doesn't project for a major increase to his role. He'll return as the top handcuff to Charles in 2015.
Eric Decker went berserk in the Jets' Week 17 upset of the Dolphins, parlaying 11 targets into 10 catches for 221 yards and a touchdown.
Decker missed some second-quarter snaps with a shoulder injury. He returned in the third quarter to whip Dolphins RCB Cortland Finnegan all over the field, including for a 74-yard touchdown. Decker's first year in New York was a success, quietly finishing with 74 catches for 962 yards and five scores. He may not be a "No. 1 wideout" in the truest sense, but he's awfully close. We'd argue Decker was less a "product of Peyton Manning" than many made him out to be. Decker is owed just $5 million in 2015 and will be safely back with the Jets, despite front-office turnover. He could prove to be a value pick in 2015 re-draft leagues, depending on which direction the Jets take at quarterback.
Nate Washington was held without a catch on three targets in Sunday's Week 17 loss to the Colts.
Washington shed tears in the locker room after the game, knowing his NFL career could be over. He enters free agency as a 32-year-old (in August) receiver who posted a 40-647-2 line in 2014. Washington's best chance of latching on somewhere is as a Jason Avant kind of No. 4/5 receiver who is brought in for veteran leadership.
Andrew Hawkins caught 4-of-7 targets for 33 yards Week 17 against the Ravens.
Hawkins finishes the year with 63 receptions for 824 yards and two touchdowns. Hawkins looked like a shrewd free-agent acquisition after catching 21 passes through the first three weeks of the season, but his play tailed off as the season progressed. A diminutive slot receiver, Hawkins does not score enough touchdowns to be viable in standard scoring, though he could have some upside in PPR formats if the Browns quarterback situation gets fixed before 2015.
Chris Johnson rushed 10 times for 20 yards and lost three on his lone reception in the Jets' Week 17 win over the Dolphins.
Johnson finishes his first year as a Jet with 155 carries for 663 yards (4.28 YPC) and two touchdowns. He added 24 receptions. Johnson's yards-per-carry average looks decent on paper, but was puffed up by a handful of longer runs. He is a classic boom-or-bust runner. Johnson is no better than a role player at this stage of his career, and faces a highly uncertain future in New York. He's 29 years old and owed $4 million in 2015. The Jets' next GM figures to cut ties with Johnson, at which point he would not be a highly-sought-after commodity on the free agent market.
Pierre Garcon caught 2-of-5 targets for 53 yards in the Redskins' Week 17 loss to the Cowboys.
Garcon closes the book on 2014 with 68 catches for 752 yards and three scores. All three totals are essentially half Garcon's 2013 numbers. That's due in large part to the fact that he drew just 105 targets one year after racking up 184. He's not a featured player in coach Jay Gruden's offense, and that could be a problem, as he's due $7.1 million in 2015. Garcon will likely be back with the Redskins, but it won't be as more than a mid-range WR3 for fantasy purposes, especially if a scattershot Robert Griffin III remains under center.


text:
May 7, 2013
We the undersigned, vehemently condemn the arrest and detention of Former Deputy Mayor and General Secretary of the
National Unity Alliance (NUA), Azath Salley, by a team of officers from the Criminal Investigation Department (CID) and the Terrorism Investigation Department (TID), on Thursday, 2 May 2013 morning, and call for his immediate release in […]
The arrest of former Deputy Mayor of Colombo and leader of the newly formed Muslim Tamil National Alliance Azath Salley under the Prevention of Terrorism Act (PTA) highlights the vulnerability of those who stand in opposition to the government on the question of the civil and political rights of the country’s ethnic and religious minorities. […]Read More
The government has made moves to acquire over 6381 acres of privately owned land in the Jaffna peninsula, which it says is for a public purpose. The public purpose is presumably for the security forces. The pasting of notices on trees in Valikamam North under section 2 of the Land Acquisition Act
coincides with preparations for […]
A prominent Muslim politician and government critic arrested today in Sri Lanka must be immediately released or charged with an internationally recognizable criminal offence, Amnesty International said.
Azad Sally, the leader of Sri Lanka’s newly formed Muslim Tamil National Alliance, was reportedly taken into custody on Thursday morning by the intelligence services for unknown reasons.
Sally has […]
Ashraf Nagar: The courageous struggle of peasants against the forcible land acquisition in Ampara District
A Statement by Women’s Action Network
Ashraf Nagar’s inhabitants can trace back their history to 1952 when it consisted of the following small villages -Aalim Nagar, Vilankadu, Kasangkeni, Muthiriyadiwattai, Pallak Kadu, Sinna Pallakkadu, Kattu Vattai, Ali Mudakadu and Aalim Chennai. Ashraf Nagar’s name was changed in the year 2006 to Oluvil first division and even though […]
I am the 43rd Chief Justice of the Democratic Socialist Republic of Sri Lanka. As the Chief Justice, I have an obligation and an unwavering duty towards the judges, lawyers and the citizens at large of my country.
I stand here before you today having been unjustly persecuted, vilified and condemned. The treatment meted out to […]
BASL Statement (8th January 2013)
The Bar Association of Sri Lanka strongly, unequivocally and with no reservations whatsoever condemns the decision to take up for debate the impeachment motion against her Ladyship the Chief Justice Dr. Shirani A. Bandaranayake based on the findings of the Parliamentary Select Committee which was quashed by the Court of Appeal and determined to be […]
Statement issued by the Judicial Service Association of Sri Lanka.
The Supreme Court of the Democratic Socialist Republic of Sri Lanka exercising exclusive jurisdiction to interpret the Constitution vested under Article 125 of the Constitution has held that the Parliamentary Select Committee procedure which found the Chief Justice Dr. Shirani Bandaranayake guilty was unconstitutional.
The Judicial Service […]
On 26th September, 2012 at the request of the National Issues Committee of the OPA, I drafted a press statement which was issued by the then President on 27th September under his signature and was thereafter unanimously approved by the OPA Forum on 28th September 2012.
Sad to say, the only apparent result of that statement […]
Women’s Action Network (WAN), as a collective of 11 women’s groups from the North and the
East, is deeply concerned by the recent efforts to recruit women into the military in the districts of Killinochchi and Mullaitheevu.
Post-war development has failed to provide the most basic needs for those who live in Killinochchi and Mullaitheevu, especially the […]

domain: news


text:
How long do I have to wait after having Coolsculpting before I can get liposuction or a noninvasive alternative like Vanquish?
Doctor Answers 4
Coolsculpting before liposuction
Coolsculpting and Liposuction
Coolsculpting is a fabulous non-invasive fat loss tool. It should not have been such a painful procedure. I would definitely wait the full four months before having any other invasive procedure. It takes at least 4 months to see the full effect of cool sculpting.
You might also like...
How long to wait after CoolSculpting before having liposuction or a noninvasive alternative?
These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.

domain: medical


text:
Black resin Cartier Diabolo de Cartier fountain pen with palladium-plated cap, pocket clip, black cabochon accent at top, twist cap closure and brand stamp at surface.
Silver-tone metal Cartier Must de Cartier ballpoint pen with CC logo medallion accent and retractable twist closure. Includes box and case.
Silver and gold-tone Cartier Les Must pen with etched swirl design. Includes box.
Silver-plated Cartier Must de Cartier Fountain Pen with etched motif throughout, 18K yellow gold nib and signature tricolored rings at push cap closure.
Gold-tone Cartier Pasha de Cartier fountain pen with rose gold-tone and silver-tone interlocking accents at cap, blue cabochon accent at cap, fluted features, pocket clip and 18K yellow gold nib with cap closure. Includes fitted box. Dated 1989.
Silver tone Cartier Vendome fountain pen with gold tone ribbon motif and engraved logo at cap.
Limited Edition. 416/1847. Solid ebony wood and palladium-plated Cartier Louis Cartier Dandy fountain pen with palladium trim, black enamel cabochon at bottom, pocket clip and screw cap closure. Includes case. Circa 2002.
Brown leather Cartier notebook with creme contrast stitching, foil stamped logo accent at reverse, gilt-edged blank pages at interior and pull-through closure at front. Includes box and dust bag.
Black leather Cartier notebook with brown contrast stitching, foil stamped logo accent at reverse, gilt-edged blank pages at interior and pull-through closure at front. Includes box and dust bag.
Limited Edition. Sterling silver rare Cartier Santos Exceptional fountain pen inspired by famous Brazilian aviator featuring 9kt gold screws throughout, cockpit-shaped tip at twist off cap, 18kt gold accents at nib and brand signature at propeller shaped clip. Numbered 0252 of 1904. Includes 10 cartridges, carrying case and box. Metal Type: Sterling Silver and 9kt gold Hallmark: Sterling Metal Finish: High Polish Total Item Weight (g): 94.07
Sterling silver Cartier ballpoint pen with gold-plated logo at pocket clip and twist retractable closure. Includes box.
Black enamel Cartier Roadster rollerball pen with gold-tone trim, blue resin cabochon at top, engraved details and twist retractable closure. Includes case.
Red lacquer and gold-plated Cartier Trinity rollerball pen with trinity bands at top, pocket clip and push cap closure. Includes pouch.
Black leather Cartier notebook cover with four card slots, multiple slit pockets and silvered brand stamp at interior. Includes card of authenticity, blank Cartier paper, address book insert and box.
Black resin and mixed gold-tone Cartier Trinity de Cartier rollerball pen with brand stamp at top, pocket clip and screw cap closure.
Black calfskin leather Cartier agenda cover with silver-tone logo at front, tonal stitching, leather interior, three interior pockets and pencil. Includes certificate of authenticity and box.
Black resin and rose gold-tone metal Cartier Must de Cartier ballpoint pen with mother-of-pearl cabochon at top, clip holster and retractable twist closure. Unfortunately, due to restrictions, this item cannot be shipped internationally.
Red leather Cartier notebook holder with gold-tone hardware, logo accent at exterior and tonal leather lining featuring clear PVC trim.

domain: design


text:
Excellent work! Really pleased with how this design turned out.
Working with GM-Design was a real pleasure. He provided clean, professional looking designs, responded to feedback quickly, and worked with me to get the perfect logo for my project. While many designers only provide a couple designs, GM-Designs went out of his way to provide a bunch of logo options and in the end, I got more than I expected. I came looking for a single logo design, and instead got a logo design that I can customize at will.
I really enjoyed working with GM-Design and recommend him for anyone looking to have some graphical design work done.
He was great to work with!
- BLACK SOX
Black SOX provided our company a great design and prompt, professional follow up add on work and services. I would definitely recommend him for any design projects you are considering
Was great to work with and put fourth a quality design based on my requirements.
I've been coming back to LU for a few years now, and I am always very happy with the outcome! Consistently brilliant!
How Kyotae started their logo design journey
Who are you known as?
COASTAL - Landscaping • Paving
Tell us a bit about who you are and the people you reach
Landscaping installations such as patios, walls, driveways, walkways and also asphalt Paving of commercial and residential driveways and parking lots
What industry do you think your business is most related to?
To give us an idea of the overall feeling of your brand, let us know which styles you lean towards
Logo will need to fit onto truck doors. Should be easy to read. Our trucks are white or black. Will attach examples of our current logos. My father and I owned two seperate company's, coastal Paving and Coastal landscaping. We have now joined company's and would like a logo that works for both. I like the idea of having the logo say - Coastal with Landscaping • paving underneath ? Open for suggestions. I will attach photos of existing logos and also a photo of a new truck we would like the new logo on. I am would like to stick with the lighthouse theme but am open to suggestions. Wave, ocean theme etc.


text:
The Virtuosos of the Berlin Philharmonic and the Vienna Orchestra, by candlelight.
The famous concerts of Pedraza, which require restricting access to the medieval village, will be held on Saturdays July 4 and 11.
The Villa de Pedraza Foundation already has the poster for the 2020 Candle Concerts, which will be held on Saturdays July 4 and 11 and in which the Virtuosos of the Berlin Philharmonic and the Vienna Chamber Orchestra will perform. The concerts will be at 22 pm, on the esplanade of Pedraza Castle, which, like the rest of the medieval village, will be lit with thousands of candles. Tickets are already on sale in advance.
On Saturday, July 4, the Virtuosos of the Berlin Philharmonic will be on stage, returning to the Segovian village after the success harvested in 2017 with a repertoire of pieces from Svendsen, Grieg,
Boccherini, Massenet and Strauss. On the second Saturday of July, the esplanade of Pedraza Castle will be filled with the sounds of the components of the Vienna Chamber Orchestra.
Since 2017, the Villa de Pedraza Foundation established a limited capacity agreed for reasons of accessibility, capacity and safety of residents and visitors to enjoy the beauty of Pedraza, under the light of thousands of candles. In addition to the people who attend the concerts, 5.000 free admission tickets are provided each day, to which we must add the people who have reservations in the different hotel establishments and restaurants. Last year, free passes to access the medieval village during concerts sold out within four hours of offering.
It was in 1951 when Pedraza was declared a Monumental Complex, Today, it is considered to be one of the most beautiful and best preserved medieval villages in Spain.
If you want more information and purchase tickets, click here.


text:
DEHRADUN: The Supreme Court
(SC) on Friday stayed an order of the Nainital high court (HC) delivered in December last year which prohibited any type of mining in the river Ganga
Welcoming the stay order, state government officials said that the apex court’s decision will give a boost to developmental activities in the state as raw material (stones picked up from river bed) would now be available for construction work.
“We will ensure only scientific picking of extra material is done from the river bed in Uttarakhand. Moreover, this will be done only after getting permission from all levels. Mining has a ripple effect on the overall economy of the state. That is why we had argued before the court that it’s necessary to remove extra river bed material to regulate the water flow,” Sailesh Bagoli
, secretary, mining, told TOI.
A division bench of Justices Rajiv Sharma
and Alok Singh of the Nainital high court had in an order dated December 5, 2016 banned all mining in the Ganga in Uttarakhand as part of a judgement delivered in a case between petitioner Mohd Salim and the state government. The order came as a blow to the entire mining industry in Uttarakhand which employs thousands of people and had contributed almost Rs 30 crore in annual royalties to the state last year.
Subsequently, the state government had filed a Special Leave Petition (SLP) in the Supreme Court seeking lifting of mining ban in Ganga. Vinay Shankar Pandey, director of the state mining department, said that the HC Ganga mining ban had come at a crucial time in the state’s mining cycle. “No mining takes place between June and October and by the time mining started the high court’s ban order came,” said Pandey.
Incidentally, on April 10, the SC had stayed another order of the Nainital high court dated March 28 through which the court had imposed a four-month ban on mining in the state.
(Inputs by Vineet Upadhyay)

domain: politics


text:
The will constricts. To do becomes have done.
Of all the amber stains the dappled light
of morning spreads across the body, none
reveals the wound that matters. None has quite
the look or feel of scattered shot, how holes
converge and bleed as one. How presence drains
the past of love. How memory extolls
the pain as virtue undersold, a grain
of poison pressed beneath the tongue
until its burn subsides. It’s not enough
to splinter the sun, the jagged shards hung
like teeth from a string at the throat, to toughen
up, to shut it down. There’s still the matter
of what remains. The chalk outline. The splatter.
–from The Seed Vault (2019). Reprinted by permission of Eyewear Publishing.
Lucas Jacob is the author of the full-length poetry collection The Seed Vault (Eyewear Publishing, 2019) and the chapbooks A Hole in the Light (Anchor & Plume Press, 2015) and Wishes Wished Just Hard Enough (Seven Kitchens Press, 2019). His poetry and prose have appeared in print journals including Southwest Review, Hopkins Review, and RHINO, and online in journals including Valparaiso Poetry Review, Sequestrum, and Jet Fuel Review. He is a high school teacher and writing-instruction consultant whose career has brought him many wonderful things, including the honor of serving as a Fulbright Fellow in Budapest, Hungary. His author site is http://lucasjjacob.com and he can also be found on Twitter at @Lucas_J_Jacob
Next Page (Hector René Del Campo)


text:
QooApp APK is considered as a web of video games from all over Asia specifically for Android devices. QooApp APK is a heavenly destination for the video game addicts offering all the popular and lesser known games. Pokemon Go, Dragan Ball Z Dokkan Battle, Dragon ball Legends, SuperStar SMTOWN, Fire Emblem Heroes, Granblue Fantasy etc. are few most played and top-ranked games bring forth by new QooApp, recently updated in the year 2018.
Intuitive user interface and well-arranged tabs are another reason behind the acclaim of QooApp Android app. The home page of QooApp welcomes you with 4 prominent tabs viz., Games, Upcoming, Events and Forum.
Under the games tab, players will find all the games ranging from high to low rated ones, coming from varied categories along with a detailed description of each game. This facilitates players to pick the game of their choice & interest. It’s easy to sort the games by their popularity and types.
Besides that, QooApp APK has a separate ‘Upcoming’ section, to list out all the awaited games. In this section, players can keep an eye on their favorite games to be launched soon. ‘Events’ and ‘Forum’ are the other 2 sections, where all the incidental events are listed in the chronological order and forms a community of players where they can post messages & share their experiences. So, get on to know more about QooApp download and its features and read on.
App Name: QooApp APK
Developer: Young Developers
Supported Version: Android 4.0.3+
Last Updated: November 16, 2018
The latest available version for QooApp APK download is 7.6.3. Simply click the button below to download QooApp APK for Android and install it to unlock a whole new world of games in absolutely no cost. With acquiring least of the device storage, QooApp APK is possible to install on all the Android devices running on 2.3 or higher OS.
Latest QooApp APK File Information
|App Size||16.1 MB|
|Supported Version||Android 4.0.3+|
|App Developer||Young Developers|
|Last Updated||November 16, 2018|
Features of QooApp APP
- A perfect game market for Android users.
- Simple, easy and orderly presentation of app items and features.
- No need to create an account for getting games from QooApp app.
- Apart from English, QooApp is also convenient for Japanese, Chinese and Korean languages.
- Make your own ‘Watchlist’ and add the games you like to install.
- Update the app instantly using the option of ‘Check for update’.
- Get suggestions for the exciting and interesting games right in the QooApp app.
- Invite your friends to play along.
- Check the details and ratings of any game & play the trendy games.
Latest Screenshots of QooApp APK
QooApp is the second to none alternative for serving all the game needs of Android users. As seen from its convenient and useful features, it can be concluded that, QooApp APK is one of the most comprehensive Asian video game mart, which offers its services for free. Although most of the games rolled out on QooApp Android platform are not in native English language, but then does language really matters while playing games? Of course not!
Take this as an official website to reach out the authenticated source of QooApp APK Download. There’re some websites like APKpure, uptodown, APK mirror including Appvn and Reddit that might result in impairing your device quality with buggy APK files full of viruses. Assured of safe and secure installation of QooApp through this page. Happy game time!

domain: entertainment


text:
International dance monolith Wilkinson returns with new single ‘If You Want It’, out now on his own Sleepless Music label.
Centring around the most alluring of Childish Gambino samples, ‘If You Want It’ is a contemporary D&B track destined to continue Wilkinson and Sleepless Music’s ventures into bold, exciting new avenues.
It becomes the latest release on Sleepless Music, an imprint that has been set up to ensure that the music always comes first for performing artists and DJs, following on from ‘Keep Dancing’ and ‘Frontline’, tracks that have amassed over five million streams.
Listen to ‘If You Want It’ by Wilkinson on the Shoot Music New Releases Playlist on Spotify.
A typically prolific 2021 has seen Wilkinson remix international electronic lynchpin Diplo and fellow D&B titan Sub Focus, plus take a trip to New Zealand were he became the fastest electronic act to sell out a tour in the country’s history.
Further headline performances at Return II Dance, Radio 1 Dance Weekend and a special performance at the McLaren’s Silverstone Grand Prix afterparty are but a few moments of note in what has been another whirlwind year for the legendary producer & DJ.
New music coming this Friday. Approved by Childish Gambino. pic.twitter.com/i8A6YtH18x
— Wilkinson (@WilkinsonUK) September 14, 2021
One of the most recognisable names from the world of D&B, Wilkinson has sold out Brixton
Academy twice, amassed half a billion streams across his back catalogue, worked with
artists such as Naughty Boy, Laura Mvula, Wretch 32, Jem Cooke and Karen Harding, and
even scored a platinum UK Top 10 hit with 2013 smash single ‘Afterglow’ featuring Becky
Hill. He is also the #1 D&B artist in the world this year in terms of both streaming and ticket sales.


Dear Peninsula School District High School Families,
To assist families with accessibility to COVID-19 vaccines, Peninsula School District is partnering with Tacoma-Pierce County Health Department (TPCHD) to offer free Pfizer COVID-19 vaccines to students/staff ages 12 and up on-site at Gig Harbor (Auxiliary Gym) and Peninsula (Robotics Lab near Roy Anderson Field) high schools.
First Dose Vaccine - June 1, 10:00 am - 4:00 pm
Second Dose Vaccine - June 22, 10:00 am - 4:00 pm
Families of Track B students can choose for their student to be vaccinated during their in-person building day. All other families (Track A, Track C, or Track B students wishing to receive the vaccine after school) would need to provide transportation to/from school at a time that's convenient. District transportation is not provided for those who have a vaccination appointment time that is after school or while they are learning remotely.
In accordance with our safety protocols, visitors are not allowed in our school buildings. Families transporting their students are asked to wait in the parking lot while their student receives the vaccine. Healthcare providers from TPCHD will administer the vaccines and a licensed health care provider will be on site in the event of any reactions to the vaccine.
Families will need to review the Emergency Use Authorization form and complete the pediatric consent forms below. If over 18, students can use this adult consent form.
Emergency Use Authorization for Pfizer - FDA
Here are the sign-up links to schedule an appointment:
Gig Harbor High: Check email for link to sign-up
Peninsula High: Check email for link to sign-up
The second dose appointment will be made at the time of the first vaccine appointment. If you would only like an appointment on the second date, a link will be sent soon. Students MUST bring the completed consent form with them to their vaccine appointment.
Hard copy parent consent forms are available by calling the health room at your child’s school:
Gig Harbor High School: 253-530-1424
Peninsula High School: 253-530-4424


text:
Parasitic copepoda from marine coastal fishes in the Kaikoura-Banks Peninsula region, South Island, New Zealand. With a key for their identification (1985)
Type of ContentJournal Article
PublisherNew Zealand Natural Sciences
ISSN0113 - 7492
Showing items related by title, author, creator and subject.
Stephenson, Wayne J. (University of Canterbury. Geography, 1997)Shore platforms on the Kaikoura Peninsula have been examined to determine the roles of marine and sub aerial weathering processes in platform evolution. Erosion was measured to assess rates of development and processes of ...
Earthquake Source Identification and Characterisation for the Canterbury Region, South Island, New Zealand Pettinga, J.R.; Yetton, M.D.; Van Dissen, R.J.; Downes, G. (University of Canterbury. Geological Sciences, 2001)
Some helminth parasites of freshwater birds from the South Island , New Zealand, with particular reference to trematodes of ducks Rind, S. (New Zealand Natural SciencesMauri Ora, 1974)


text:
MINDEN — If you’re familiar with the Minden area and southern Kearney County, you may recognize the strong strain of Danish heritage that runs through the community.
The phone book is full of names like Petersen and Nielsen, Madsen and Sorensen, Jacobsen and Jorgensen, Christensen and Hansen and Larsen, among others. Minden once had an annual Danish Days festival, its own troupe of Danish Dancers, and frequent meetings of the Danish Brotherhood lodge. The Paschal Candle holder at the Fredericksburg Lutheran Church south of Minden was donated to the congregation by the Danish royal family.
Because of all this, when you see advertising throughout the region right now for “Hans Christian Andersen” appearing at the Minden Opera House, your first thought may be that Minden is celebrating its own culture. And in a way, that’s right.
The larger truth, however, is that Hans Christian Andersen, the son of a humble 19th-century cobbler and an illiterate washerwoman from the Danish city of Odense, belongs to all of humanity — and the story based on his life that will appear on a Minden stage over the next three weekends is relevant to the culture of anyone who grew up in the Western world and was ever a child.
“Hans Christian Andersen: The Musical,” featuring a cast of more than 50 actors, opened Friday at the Minden Opera House. Remaining scheduled dates are March 14, 15, 19, 20, 22, 26, 27, 28 and 29. Sunday performances are at 2:30 p.m., while all other shows are at 7:30 p.m. No performance is scheduled for March 21.
As of Friday, the show was expected to continue as scheduled despite the current concerns about COVID-19.
Tickets are available online at https://www.mindenoperahouse.com/.
While Hans Christian Andersen may not be a household name, his fairy tales are eminently recognizable. They include “The Emperor’s New Clothes,” “The Little Mermaid,” “The Princess and the Pea,” “The Ugly Duckling,” “The Little Match Girl” and “Thumbelina.”
In all, he has 3,381 titles to his name, and his works have been translated into more than 125 languages — the second-largest number of languages, it is said, of any literature in the world except for the Bible.
Yet Ken Vyvlecka of Kearney, a veteran cast member and director in Minden Community Players productions, admits he knew little about Andersen before beginning preparations for the musical last fall.
He credits Glen Haselbarth of Minden, another MCP veteran who has been involved for many years in Danish cultural activities in the community, with promoting the “Hans Christian Andersen” script.
Haselbarth is music director for the production.
“Glen’s a nice Dane, so he was very anxious to do this play,” Vyvlecka said with a smile.
Once the script was selected, he said, he went to work researching Andersen’s life, Danish culture and the script itself, with the book by John Fearnley, Beverley Cross and Tommy Steele and music and lyrics by Frank Loesser.
“I started back in September reading and trying to visualize what this could look like in my mind, studying the play and trying to figure out what the writer was trying to convey.
“I go to bed with the play in my mind and wake up with the play in my mind. I think about it nonstop.”
The production is based on a 1952 musical motion picture starring Danny Kaye.
The story begins with Andersen (portrayed by Jacob Knudsen), who is presented as a struggling cobbler in Odense, who moves on to Copenhagen after the local schoolmaster complains to the town fathers that Andersen is filling his pupils’ minds with nonsense, telling them stories to make their schoolwork more accessible and easier to understand.
In Copenhagen, a series of events leads to Andersen making the acquaintance of Madame Doro (Grace Vyvlecka), a prima ballerina, writing the story of “The Little Mermaid,” which eventually is turned into a ballet with Andersen as narrator. In the end, Madame Doro and her husband present Andersen with a special order from the King of Denmark proclaiming him to be “The King of Stories.” (For a more complete synopsis, you’ll have to see the show.)
Vyvlecka said audiences can expect to see an uplifting show with beautiful singing and dancing, and featuring Knudsen’s operatic voice in the role of Andersen.
As director, he said, he has been working hard on technical details such as lightning-fast set changes to keep the action moving.
All his memorable stories aside, Vyvlecka said, Andersen’s own story is worth knowing and celebrating — especially in a community with proud Scandinavian heritage like Minden.
“I think of a person who thought of himself as very simple but had a tremendous gift,” Vyvlecka said. “The story of the Ugly Duckling is really a story about himself.”
For ticket information, contact the box office at 308-832-0588 or mindenoperahouse.com.
For shows on opening weekend, one free youth ticket comes with each paid adult admission. The promotion code is “Mermaid.”
The Minden Community Players are a nonprofit organization.
“Our goal is to inspire the youth and have them gain an appreciation for the arts, and theater specifically,” Vyvlecka said.

domain: literature


text:
The Sanyo LCD32XR9DA is a reasonably priced 32in LCD television with a high brightness level and good up-scaling of low resolution sources. This makes it a good choice for anyone wanting to watch their DVDs on a new screen without breaking the bank.
The Laser DVBT-ST35 is a 3.5in portable LCD TV with a touch screen and an internal digital television tuner and aerial. It has a rechargeable battery, so you can use it to watch TV on the move, but a poor internal antenna means the unit is only usefu...
The Toshiba 19DV615Y is a 19in LCD television with an integrated DVD player. It has good picture quality for its size and the multimedia features are easy to use. If it was cheaper, we’d have no problems recommending it over competitors.
The Sharp LC40LB700X is a 40in LED-backlit LCD television with great picture quality, vivid colours and an integrated Blu-ray disc player. It’s the most powerful all-in-one television we’ve seen, and its sharp and colourful images help to make it a g...
The Teac LCDV2655HD is a 26in LCD television with an integrated DVD player, a high-definition resolution and a simple interface.
The LG 50PS80ED is a good 50in plasma television for anyone who watches a lot of broadcast television and wants something that looks great. It has a few features that set it apart from the crowd, including an internal hard drive.
The Sony Bravia KDL32W5500 is a Full HD 32in LCD television with multimedia features, good picture quality and a modern design. It’s one of the best mid-size LCD screens we’ve tested, but its price is double that of some other 32in TVs we’ve seen.
Kogan’s 1080P-32 is a good mid-size LCD television for a budget buyer. It has picture quality good enough to enjoy Blu-ray movies, although you’ll need a separate sound system to really get the most out of them.
The Teco TAL2226 is a 22in LCD television that is well suited as a backup screen in a study or bedroom; it is sufficient for casual television watching.
The Sony Bravia KDL52Z5500 is a 52in LCD television with a 200Hz refresh rate. It’s the successor to the Bravia KDL52Z4500, with a new video processor and improved multimedia playback. The TV gives you a lot of control over motion control and picture...
The Hisense HL119V88PZ is a budget 47in LCD TV with a 100Hz mode. Marketed at a very reasonable price, it’s a big screen with decent picture quality, although enthusiasts would be well advised to look further afield.
The Hisense HL81V68P is a 32in (81cm) LCD television aimed at budget buyers. It’s not as advanced as TVs from the big-name brands but it has acceptable picture quality for the casual viewer.
The Sony XEL-1 is an OLED television with an 11in screen and a price-tag of $7000. While this combination guarantees it will only make it onto the sprawling mahogany desks of ultra-rich executives, there’s little doubt that it has the best picture qu...
Samsung's 46in Series 8 (UA46B8000) LED TV is the most 'complete' television we've seen so far: it offers Internet and network connectivity, multimedia playback features and LED backlighting.
The Teac LCD228HDM is a 22in LCD television with a multi-card reader and USB 2.0 port that let you display photos and play videos and music. A range of inputs allows external devices like an HDD recorder or desktop PC to be connected.
Most Popular Reviews
- 1 Playing chicken with a Tesla Model S
- 2 Audi TT (2015) review: A smarter take on the sports coupe
- 3 Microsoft Lumia 640 review: Honouring Nokia's legacy
- 4 Apple Watch review: saving time
- 5 Samsung SUHD smart TV (JS9500) review
Join the Good Gear Guide newsletter!
Deals on Good Gear Guide
- Networking, Wireless & VoIP
Deals on Good Gear Guide
Latest News Articles
- Google, Apple streaming devices shake up the TV market
- Dick Smith slashes prices on tech from Apple, Samsung and more
- Sharp's latest 4K TV adds yellow subpixel for 8K resolution
- Panasonic Viera TV range for 2015: 4K, Netflix, and Firefox OS
- 15 Samsung UHD TVs launch with support for Netflix, Stan and Presto
GGG Evaluation Team
First impression on unpacking the Q702 test unit was the solid feel and clean, minimalist styling.
For work use, Microsoft Word and Excel programs pre-installed on the device are adequate for preparing short documents.
The Fujitsu LifeBook UH574 allowed for great mobility without being obnoxiously heavy or clunky. Its twelve hours of battery life did not disappoint.
The screen was particularly good. It is bright and visible from most angles, however heat is an issue, particularly around the Windows button on the front, and on the back where the battery housing is located.
My first impression after unboxing the Q702 is that it is a nice looking unit. Styling is somewhat minimalist but very effective. The tablet part, once detached, has a nice weight, and no buttons or switches are located in awkward or intrusive positions.


text:
The Charters of the Cinque Ports – Are They Still Needed?
- Graham McBain
AbstractThe Cinque Ports were a collection of ports on the east coast of England which - from early times - were granted, by charter, a number of Crown prerogatives in return for providing a ship service to the Crown. The earliest charter still extant dates from 1278. However, there may have existed charters granted by sovereigns to some - or all - of the Cinque Ports going back to the time of Edward the Confessor (1042-66). The original Cinque Ports were the ports of Hastings, Dover, Sandwich, New Romney and Hythe. To these five ports were added - probably prior to 1210 - the towns of Winchelsea and Rye. And to these were later added corporate and non-corporate members (or limbs), being other smaller ports. The heyday of the Cinque Ports was in medieval times when they provided a vital navy for the protection of the realm. Today, the Cinque Ports, and their charters, still exist. However, the purpose of this article is to review the terms and meaning of these charters, in order to determine whether they are now obsolete and should be cancelled. That is the conclusion.
This work is licensed under a Creative Commons Attribution 4.0 License.
- Academic Journals Database
- CNKI Scholar
- DTU Library
- Elektronische Zeitschriftenbibliothek (EZB)
- EuroPub Database
- Excellence in Research for Australia (ERA)
- Genamics JournalSeek
- Google Scholar
- Harvard Library
- IBZ Online
- PKP Open Archives Harvester
- Standard Periodical Directory
- Technische Informationsbibliothek (TIB)
- The Keepers Registry
- UCR Library
- Universe Digital Library
- Zeitschriften Daten Bank (ZDB)
- Paige DouEditorial Assistant


Our Youth Month cover star, Tony X, has a new single out. Titled “Lerato”, the track is a ballad that speaks on young, African love. Having been relatively quiet since releasing his debut EP, Just In Case, over a year ago Tony’s been crafting his new sound which he says is more a representation of […]
The tale of the musician who began performing in church and graduated to the bright lights of the secular music industry is one as old as time. Their voices usually enhanced by the discipline and training required by the church choir, this is the back story to one of Punchline’s finest; Tony X. “My parents […]
The Plug presents a quick, behind the scenes look at our Punchline Media shoot for Youth Month. Featuring Manu Worldstar, Luna Florentino, Dee XCLSV, and Tony X, head over to the Covers tab to peep their stories. Video shot and edited by Loddy Thabang.
To coincide with their cover of The Plug for Youth Month, we have the exclusive on Punchline Media’s new single “Party Up, Get Paid.” Out on all streaming platforms tomorrow, have a look at the official cover art below. Look familiar? 😉
In choosing the the creative direction for the group cover, we wanted to pay homage to the one of the greatest hip hop covers of all time; the Vibe Death Row Cover of 1996. 96 was an iconic year for hip hop. Referencing that cover meant showing – just like Death Row at the time […]


text:
After the move of TJ Maxx downtown, Lansing residents can anticipate the arrival of two new franchises instead of one: a Dollar Tree store and a Planet Fitness. The Planet Fitness will be moving from the Shops at Ithaca Mall, located across the street from their new location.
At the planning board meeting last night, the plan to introduce the two businesses to 2309 Triphammer Road cleared another hurdle, as the board said that only a few clarifications were necessary before a special permit could be issued to begin renovations.
The plan is seeking to renovate the facade of the building, as well as the facade of the Big Lots next door. A special permit was necessary, Mike Scott said, because of rules regarding the number of parking spots necessary and because of the height of the new signage; current rules prohibit facades higher than 35 feet.
The new Cayuga Mall additions would likely not be open until at least the holidays, the presenter estimated. Aside from exterior changes, the work would also involve emergency renovations of the roof, building a dividing wall to separate out the currently-open interior and all internal building.
The board also touched on the issue of increasing the “pedestrian-friendliness” of the village by having more sidewalks and walkways. The board examined previous walkway implementation plans from 1995 and 2000, and decided to continue to examine the issue in the future.
Arrowhead Ventures also submitted a request to have 18 single-family senior housing units instead of 12, which the board deemed a minor change. The site will continue as planned on Oakcrest Road.
The next planning board meeting will take place on July 30.


text:
Your Custom Text Here
One of our assignments this quarter was to make a promotional piece and mail it to our professor. My girlfriend bought me this awesome wax seal, so I figured I should utilize it.
Ah, yes. Halloween in Athens. It's a joyous occasion when our population doubles and chaos hits the streets. Thanks to our friends Chris and Chloe, I got to go on their fire escape looking over one of the stages. This is just one side of the street!
The guys at 69 E. Stimson got a cat. Her name you ask? We don't know yet. But she still rocks.
Mmm...coffee. A beautiful thing. I photographed some beans and brewed coffee for Archer who runs a blog at www.archerfriendly.com. Check it out.


text:
Building Capacity for AT Services through the Language of Problem-Solving
Presented by Daniel Cochrane, MA, MS, ATP
The need to move toward a capacity-building model in the provision of assistive technology services has been promoted by DeCoste and Bowser in workshops and online classes for at least five years (DeCoste, 2014). It requires building a common understanding within a school district of what assistive technology is and how we decide whether a student would benefit. We can do this by harnessing the common language of the problem-solving cycle, the core decision-making process of RtI and MTSS, instead of introducing an isolated acronym-based decision-making framework. In this webinar, UIC clinical instructor Daniel Cochrane shows how he integrated AT into the problem-solving process as a way of building capacity in his former school district, where he served as AT coordinator for thirteen years. Combining the problem-solving cycle with the Johns Hopkins University AT Cycle and an expanded version of task-demand analysis from the Illinois AT Guidance Manual (2012), Dan created a simple but powerful visual guide to the AT process that embeds key principles of best practice in AT.
AT Decision Making

domain: library


text:
Comment, Like, & Favorite
Photograph - Photograph
Black and White photograph of the Union Square subway station entrance sign in New York City.
August 20th, 2012
Viewed 43 Times - Last Visitor from Tucson, AZ on 07/09/2014 at 11:58 PM
copy and paste to your website / blog - preview
union square framed prints, new york city framed prints, road sign framed prints, sign framed prints, signs framed prints, station framed prints, street sign framed prints, subway framed prints, subway station signs framed prints, train framed prints, trains framed prints, big apple framed prints, empire state framed prints, manhattan framed prints, nyc framed prints, nyc street signs framed prints, new york framed prints, new york city the city that never sleeps framed prints, u.s. framed prints, usa framed prints, united states framed prints, united states of america framed prints, america framed prints, black & white framed prints, black and white framed prints, union square greeting cards, new york city greeting cards, road sign greeting cards, sign greeting cards, signs greeting cards, station greeting cards, street sign greeting cards, subway greeting cards, subway station signs greeting cards, train greeting cards, trains greeting cards, big apple greeting cards, empire state greeting cards, manhattan greeting cards, nyc greeting cards, nyc street signs greeting cards, new york greeting cards, new york city the city that never sleeps greeting cards, u.s. greeting cards, usa greeting cards, united states greeting cards, united states of america greeting cards, america greeting cards, black & white greeting cards, black and white greeting cards, union square prints, new york city prints, road sign prints, sign prints, signs prints, station prints, street sign prints, subway prints, subway station signs prints, train prints, trains prints, big apple prints, empire state prints, manhattan prints, nyc prints, nyc street signs prints, new york prints, new york city the city that never sleeps prints, u.s. prints, usa prints, united states prints, united states of america prints, america prints, black & white prints, black and white prints, union square posters, new york city posters, road sign posters, sign posters, signs posters, station posters, street sign posters, subway posters, subway station signs posters, train posters, trains posters, big apple posters, empire state posters, manhattan posters, nyc posters, nyc street signs posters, new york posters, new york city the city that never sleeps posters, u.s. posters, usa posters, united states posters, united states of america posters, america posters, black & white posters, black and white posters


: 1024 x 768 Pixel
: Wednesday, 31 Jan 2018
The Alfa Romeo 75 (Tipo 161, 162B), sold in North America as the Milano, is a compact executive car produced by the Italian automaker Alfa Romeo between 1985 and 1992. The Alfa 75 was commercially quite successful: in only three years, 236,907 cars were produced, and by the end of production in 1992, around 386,767 had been built.The 2018 Alfa Romeo Stelvio is a high performance SUV. Explore split folding seats, V6 turbo engine, 505 horsepower and more. Build & price a 2018 Stelvio.The Alfa Romeo 4C (Type 960) is a mid-engined, lightweight, rear-wheel drive sports car.Available in coupé and spider body style, it uses a carbon fiber tub, front and rear crash box, and hybrid rear subframe mainly out of aluminum to keep weight at 895 kilograms (1,973 lb) and 1,050 kilograms (2,315 lb) in the United States.Mar 29, 2017 · What will Alfa Romeo’s next vehicle be? According to Autocar, Fiat Chrysler Automobiles, Alfa Romeo, and Alfa boss Reid Bigland have not yet made a decision about what the segment in which the next Alfa Romeo will compete.


text:
Lost My Doggie Coupon Code
Doggie offers a further and sustainable way of detecting lost or stolen pets. My dog has lost my own experience.
I understand that finding a lost or stolen pet can be a daunting task, and there must be a never before seen.
Lost My Doggie promo codes then ask the neighbors to basically place leaflets in the region. Lost My Doggie Coupons, Coupon Codes,
Promotional Codes, Discount Codes, Promotional Codes, and Promotional Codes Lost My Doggie has developed a further and powerful way to find lost and discovered pets.
From my own understanding of losing a lost pet, I understood that finding a lost or stolen pet can be a difficult task
There should be a better way to inform the network than just flyers in the area to place.
It understands the intensity of the pain and emptiness that occurs after this loss. For this reason,
We have developed a system that you can use to find your lost pet. Everything you need to register your pet information with us and we will alert you when we search for your pets.
We send your lost and found items to local animal shelters, veterinarians and rescue groups so you are up to 25 times more visible and your pet can come home faster.
Never say goodbye and enjoy a long relationship with your pet. Use the LostMyDoggie coupon and the promotional code for discounts.
Lost My Doggie promo codes is a lost pet benefit that has helped thousands of pet owners find their lost pets.
We use innovations to communicate “Amber Alerts” for lost pets and to inform neighbors and organizations about lost pets in the region.
Our program dramatically increases the likelihood of finding a lost dog, cat or pet. It’s like helping the creature network.

domain: pet


Saturday, there was a grand opening for the new skate park in Gardner Park in Newport. In attendance for the grand opening were from left to right: Kathy Metras of NEKCA, Andy Cappello of Newport Parks & Recreation, Ira Morgan of Hellbilly Hideaway, and Michael Parker of Parker Construction.
MORGAN- Forty residents in Morgan attended a public meeting for a presentation to consider whether to lease or sell the elementary school to Turning Points Alternative Education Program (AEP). Dwindling enrollment forced the town to tuition the students to Derby Elementary School last year. The school sits idle and residents are seeking different options to make use of the facility.
For the full story see Monday's Express.


text:
Considers the proposal in the Protection of Children and Prevention of Sexual Offences (Scotland) Bill 2004 for an offence of meeting or travelling to meet children for the purpose of committing a sexual offence following grooming behaviour. Examines the definition of the criminalised behaviour, noting the requirement for intent to abuse. Reviews the preventative approach to child protection in the Protection of Children (Scotland) Act 2003.
|Number of pages||2|
|Journal||Journal of the Law Society of Scotland|
|Publication status||Published - 2005|
- child protection
- meeting children following sexual grooming

domain: sociology