Last night saw Vice magazine host its 20th anniversary party in Brooklyn, with a star-studded roster of guest performers including Jonah Hill, Scarlett Johansson, Lil Wayne, Jarvis Cocker, Andrew W.K. and Russian shock-rockers Pussy Riot.
By all accounts, however, it was the performances from non-singers ScarJo and Jonah Hill that were the highlights, with Scarlett performing a cover of New Order’s “Bizarre Love Triangle”; and Jonah rapping a singularly unique version of own Drake’s “Marvins Room.”;
“My heart’s been broken,”; Jonah joked to the crowd before launching into the rap. “I thought you and I were friends, Drake. Accept my friendship.”;
Here are some fan-shot videos the their performances:


As expected, the Federal Communications Commission voted 3-2 Tuesday to affirm its 2017 repeal of the Obama-era net neutrality rules.
The move comes around one year after a federal appellate court largely upheld the repeal, but directed the agency to consider the impact of the repeal on three issues -- whether it affects public safety, the Lifeline program (which subsidizes broadband) and regulations regarding utility poles.
The agency stated Tuesday it “found no basis” to change its 2017 decision, adding that the repeal “promotes public safety, facilitates broadband infrastructure deployment by internet service providers, and allows the FCC to continue to provide Lifeline support for broadband internet access service.”
Democratic Commissioners Jessica Rosenworcel and Geoffrey Starks dissented from Tuesday's decision.
The Obama-era rules prohibited broadband providers from blocking or throttling online traffic and charging companies higher fees for prioritized delivery. The FCC approved those rules in 2015, but voted to repeal them two years later, after a change in administration.
FCC Chairman Ajit Pai said Tuesday that the 2017 decision to repeal the former rules “has been increasingly vindicated over time.”
“The internet has remained free and open,” he stated. “The American people can still access their favorite websites. They don’t pay extra to avoid the slow lane. And they don’t have to pay a fee each time they tweet.
Rosenworcel countered in a dissenting statement that the repeal "put the agency on the wrong side of the public, the wrong side of history, and the wrong side of the law."
She added: “The rollback of net neutrality did not get us any closer to broadband for all, despite the lofty promises made by the FCC.”
Proponents of net neutrality blasted the FCC's decision Tuesday.
“This remand order callously dismisses the valid concerns of public-safety officials, competitive broadband providers and millions of disconnected low-income families who can’t afford to get online,” Free Press Policy Manager Dana Floberg stated.
Sen. Ed Markey (D-Massachusetts), who has introduced legislation to restore the former regulations, stated Tuesday he “will not rest until net neutrality is back on the books.”
“Without net neutrality protections, it’s just a matter of time before big broadband providers start raising prices, slowing down internet speeds, and making it harder for families, small business, and students to access the opportunities to recover and rebuild from this pandemic,” he stated.
Pai, who shepherded the repeal, has said the former rules were “heavy handed” and depressed investment.
But net neutrality proponents argue the rules were necessary to prevent broadband providers from limiting consumers' ability to access streaming video, search engines and other online services and content.
Advocates also dispute that the rules depressed investment. The organization Free Press, which evaluated public filings by service providers, concluded that investment by 13 major broadband providers increased in the two years after the FCC passed the net neutrality regulations.
Should Democratic candidate Joe Biden win next week's presidential election, the government could again change direction on net neutrality. The Democratic Party's current platform includes a promise to restore the FCC's “clear authority to take strong enforcement action against broadband providers who violate net neutrality principles through blocking, throttling, paid prioritization, or other measures that create artificial scarcity and raise consumer prices for this vital service.”


text:
At Danielle Neil Photography, I have a passion for photographing dogs.
Your pet is part of the family and you go above and beyond to give them the best and ensure their happiness. You want the photographs of your dog to tell a story and show their furry personality. You want images and artwork that shows their energy and enthusiasm. You want your dog’s photos to show love, life and make your heart smile when you look at them.
There are many photographers in Northeast Ohio to choose from. But most do not specialize in working with dogs. Take a look at the dog gallery to see if Danielle Neil Photography is a good choice for you. I offer sessions both outdoors and in the Boardman, Ohio studio.
My dog will not behave for photos. My pet is too wild for a photo session. My dog does not know any commands besides sit and he/she does not even do that well. I has heard all those comments while talking to my clients about their pet’s portraits.
Your dog does not have to be perfect, just themselves for their photographs! The video shows some behind the scenes moments from a dog session. Coach is without a doubt a high-energy dog and wanted to play, play and play some more! I was able to create some beautiful images for his pet parents to display in their home.
While no two dogs are alike, no two photo shoots are alike, either. Nothing during the experience is forced and I have worked with all types of animals, from high energy to extremely shy. If your dog won’t sit, it’s ok, I will chase after them. If they need to be on a leash, not a problem, the leash can be removed for the final image. The goal is to create beautiful images that show your pet’s quirks and personality — just being themselves for the camera. Relax — there are no bad dogs during photo sessions!
Raves & Reviews
I cannot say enough amazing things about Danielle.
My whole family was blown away by her friendliness, compassion, enthusiasm for our sweet bulldog Stella and just raw talent at capturing the moments that truly reflect our little lady! I would and have referred Danielle to so many people ... outside of photographing pets ... for any occasion, she is a gem to work with and you will be thanking her for years to come!"

domain: artistic


text:
So you can stay ahead of the news, here's a quick look at some of the stories ABC15 will be keeping an eye on Thursday, September 26.
GOOD SAMARITANS HONORED
Mesa Fire officials are honoring three Good Samaritans for their heroic deeds, including a 3-year-old who called 911 and a forklift operator who lifted a pickup truck of a bicyclist. 10:30 a.m., Fire Station 201, Mesa.
HELICOPTER RESCUE DEMONSTRATION
The Phoenix Fire Department will demonstrate a long-line helicopter operation for media outlets. Fire officials are expecting an increase in mountain rescue calls with the onset of cooler temperatures. 10 a.m., Fire Training Academy, Phoenix.
TEMPLE MURDERS RE-TRIAL VERDICT WATCH
The jury continues its deliberations in the re-trial of Johnathan Doody, charged with killing nine people at a Buddhist temple in the West Valley in 1991. 10:30 a.m., Maricopa County Superior Court, Phoenix.
Goodwill of Central Arizona, the City of Phoenix, and a number of veterans organizations are coming together to match unemployed veterans with employers. 10 a.m.-2 p.m., Shrine Auditorium, Phoenix.
Copyright 2013 Scripps Media, Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.
Click on the region names in the map below to see news from that region.
Things To Do
INSIDE: Check out our top pick for weekend events around Arizona!
RIGHT NOW: Top Stories
Flags were lowered to half-staff across South Africa and people in black townships, in upscale mostly white suburbs and in the country's vast rural grasslands commemorated Nelson Mandela.
Take a journey through the years to see the incredible life of former South African president Nelson Mandela, who led the struggle against apartheid in his homeland.
Still freezing across much of the state; find out how long the frigid air will stick around and how long before our next rain and snow chances return.
A family of seven escaped a house fire early Friday morning near 16th Street and Southern Avenue in Phoenix.
Eating nutritional foods is one of the best ways to reduce obesity. But following a healthy diet isn't always easy, especially for lower socioeconomic groups.
Ahead of the Mustang's 50th anniversary, Ford unveiled an all-new completely redesigned Mustang with more power, and better fuel economy.

domain: news


text:
I’m in South Africa, getting a feel for the ongoing Panthera camera trapping surveys, collating data, falling madly in love with the country and South African bush, and scheming for how I need to find a way to come back.
Things are a bit of a whirlwind, but so far I am amazed and excited about the amount of monitoring that many of the small private and state-run reserves have been doing. There is an extraordinary amount of information that has been collected over the last decade on how all of the top predators move and live across these parks. There are parks with and without lions. Parks with and without hyenas. With and without wild dogs. Some parks are big and some are small. Some are very thickly treed, others are somewhat open. (Note that one thing I discovered very quickly is that pretty much all South African habitat, even the grassland, would equate to “woodland” in the Serengeti. So…”open” is a relative term.)
The amount of data here is enough to get any science nerd’s heart a flutter. But I am trying to focus on what is out the window instead of what’s on the computer for now. I’ve only a few days in South Africa, and endless time to analyze the data.
In the meanwhile, I thought I’d share one of my new favorite animals: the nyala.
These cousins to the waterbuck we capture in camera on Serengeti, and you can see it a bit in their pretty faces. But these animals are far more stunning than anything I’ve ever seen in Serengeti. The females are small and sport bright white stripes on their red fur, and the males have these incredible “manes” that run down the undersides of their necks and to their bellies. They are pretty awesome. As is everything I’ve experienced in South Africa so far. Yep, definitely need to find a way back!
As I’m writing up my dissertation (ahh!), I’ve been geeking out with graphs and statistics (and the beloved/hated stats program R). I thought I’d share a cool little tidbit.
Full disclosure: this is just a bit of an expansion on something I posted back in March about how well the camera traps reflect known densities. Basically, as camera traps become more popular, researchers are increasingly looking for simple analytical techniques that can allow them to rapidly process data. Using the raw number of photographs or animals counted is pretty straightforward, but is risky because not all animals are equally “detectable”: some animals behave in ways that make them more likely to be seen than other animals. There are a lot of more complex methods out there to deal with these detectability issues, and they work really well — but they are really complex and take a long time to work out. So there’s a fair amount of ongoing debate about whether or not raw capture rates should ever be used even for quick and dirty rapid assessments of an area.
Since the Serengeti has a lot of other long term monitoring, we were able to compare camera trap capture rates (# of photographs weighted by group size) to actual population sizes for 17 different herbivores. Now, it’s not perfect — the “known” population sizes reflect herbivore numbers in the whole park, and we only cover a small fraction of the park. But from the graph below, you’ll see we did pretty well.
Actual herbivore densities (as estimated from long-term monitoring) are given on the x-axis, and the # photographic captures from our camera survey are on the y-axis. Each species is in a different color (migratory animals are in gray-scale). Some of the species had multiple population estimates produced from different monitoring projects — those are represented by all the smaller dots, and connected by a line for each species. We took the average population estimate for each species (bigger dots).
We see a very strong positive relationship between our photos and actual population sizes: we get more photos for species that are more abundant. Which is good! Really good! The dashed line shows the relationship between our capture rates and actual densities for all species. We wanted to make sure, however, that this relationship wasn’t totally dependent on the huge influx of wildebeest and zebra and gazelle — so we ran the same analysis without them. The black line shows that relationship. It’s still there, it’s still strong, and it’s still statistically significant.
Now, the relationship isn’t perfect. Some species fall above the line, and some below the line. For example, reedbuck and topi fall below the line – meaning that given how many topi really live in Serengeti, we should have gotten more pictures. This might be because topi mostly live in the northern and western parts of Serengeti, so we’re just capturing the edge of their range. And reedbuck? This might be a detectability issue — they tend to hide in thickets and so might not pass in front of cameras as often as animals that wander a little more actively.
Ultimately, however, we see that the cameras do a good overall job of catching more photos of more abundant species. Even though it’s not perfect, it seems that raw capture rates give us a pretty good quick look at a system.
I’ve written a handful of posts (here and here and here) about how lions are big and mean and nasty…and about how even though they are nasty enough to keep wild dog populations in check, they don’t seem to be suppressing cheetah numbers.
Well, now that research is officially out! It’s just been accepted by the Journal of Animal Ecology and is available here. Virginia Morrell over at ScienceNews did a nice summary of the story and it’s conservation implications here.
One dissertation chapter down, just two more to go!
I posted a little while ago about the applications of remote sensing technology in biological research. Here’s a TED talk by one of the authors of the South African study I mentioned with some fascinating visuals showing the level of detail these technologies can reveal to us. While the talk starts off flying you through a “lion’s-eye” view of hunting terrain, Greg Asner goes on to reveal some of the other ecological and conservation implications of these technologies and how they can help us do things from finding illegal goldmines and documenting species composition in the Amazon to tracking habitat changes by elephants and fire back in Africa.
Back in October, I wrote about how a grant proposal was turning me into a zombie.
Well, much to my surprise, turns out that my foray into the world of the walking dead was worth the effort. I’ve just heard that the National Science Foundation does, indeed, want to send me to South Africa to carry out this research!
Basically, I’m interested in how the other big carnivores (hyenas, leopards, cheetahs, and wild dogs) manage to live with lions. And I think that one of the keys to their coexistence has to do with how the other carnivores distribute themselves across the landscape to avoid being killed or harassed by lions. Do they avoid huge tracts of land and lose access to the valuable resources within? Or are they able to fine-tune their behavior and still use those areas without getting into trouble?
As you know, I’m using the camera traps to try and figure out these patterns of habitat use by the major carnivores. But that still just tells me what they do in a place (the Serengeti) where there are lions, and I don’t know if the lions are directly causing these patterns. I can’t, for obvious reasons, do an experiment where I take out all the lions and see if the rest of the animals change their behaviors, which would help me identify such a causal relationship.
But in South Africa, there are two virtually identical reserves — they have the same habitat, the same prey animals, and the same carnivores…except that one has lions and one does not. These reserves are right next to each other and surrounded by fencing. So they are pretty much the perfect experimental system where I can actually answer whether or not the patterns we see in predator behavior are caused by lions. What’s even better is that there are already ongoing research projects there that are running camera trap surveys very similar to Snapshot Serengeti. So most of my work will be doing some measurements of the vegetation and working with the researchers in South Africa to compile their data in a way that we can draw these comparisons.
It’s going to be a *lot* of computer work with a *little* bit of getting out into the bush, but the questions are so cool and the ability to effectively isolate the effect of a single top predator (lions) in a natural ecosystem is so rare, that I couldn’t be more excited about it.
Here’s a great post by the BBC about some genetic work that has just been done to shed light on the evolutionary history of lions. Apparently, it’s a bit tricky reconstructing lion history due to the fact that they don’t fossilize particularly well (generally not conducive conditions in lion habitat) and that humans create giant holes in the record by wiping out entire sub-population.
However, from genetic analyses of living lions and museum specimens, these authors have determined that there are two evolutionary groups of lions – those in India and Central/West Africa and those in Eastern/Southern Africa. This happens to have some interesting implications for lion conservation and reintroduction — check out the article!
Last week I wrote about using really simple approaches to interpret camera trap data. Doing so makes the cameras a really powerful tool that virtually any research team around the world can use to quickly survey an ecosystem.
Existing monitoring projects in Serengeti give us a really rare opportunity to actually validate our results from Snapshot Serengeti: we can compare what we’re seeing in the cameras to what we see, say, from radio-tracking collared lions, or to the number of buffalo and elephants counted during routine flight surveys.
One of the things we’ve been hoping to do with the cameras is to use them to understand where species are, and how those distributions change. As you know, I’ve struggled a bit with matching lion photographs to known lion ranging patterns. Lions like shade, and because of that, they are drawn to camera traps on lone, shady trees on the plains from miles and miles away.
But I’ve finally been able to compare camera trap captures to know distributions for other animals. Well, one other animal: giraffes. From 2008-2010, another UMN graduate student, Megan Strauss, studied Serengeti giraffes and recorded where they were. By comparing her data with camera trap data, we can see that the cameras do okay.
The graph below compares camera trap captures to known densities of giraffes and lions. Each circle represents a camera trap; the bigger the circle, the more photos of giraffes (top row) or lions (bottom row). The background colors reflect known relative densities measured from long-term monitoring: green means more giraffes or lions; tan/white means fewer. For giraffes, on the whole, we get more giraffe photos in places that have more giraffes. That’s a good sign. The scatterplot visualizes the map in a different way, showing the number of photos on the y-axis vs. the known relative densities on the x-axis.
What we see is that cameras work okay for giraffes, but not so much for lions. Again, I suspect that this has a lot to do with the fact that lions are incredibly heat stressed, and actively seek out shade (which they then sleep in for 20 hours!). But lions are pretty unique in their extreme need for shade, so cameras probably work better for most other species. We see the cameras working better for giraffes, which is a good sign.
We’ve got plans to explore this further. In fact, Season 7 will overlap with a wildebeest study that put GPS collars on a whole bunch of migratory wildebeest. For the first time, we’ll be able to compare really fine scale data on the wildebeest movements to the camera trap photos, and we can test even more precisely just how well the cameras work for tracking large-scale animal movements. Exciting!
Over the last few weeks, I’ve shared some of our preliminary findings from Seasons 1-6 here and here. As we’re still wrapping up the final stages of preparation for Season 7, I thought I’d continue in that vein.
One of the coolest things about camera traps is our ability to simultaneously monitor many different animal species all at once. This is a big deal. If we want to protect the world around us, we need to understand how it works. But the world is incredibly complex, and the dynamics of natural systems are driven by many different species interacting with many others. And since some of these critters roam for hundreds or thousands of miles, studying them is really hard.
I have for a while now been really excited about the ability of camera traps to help scientists study all of these different species all at once. But cameras are tricky, because turning those photographs into actual data on species isn’t always straightforward. Some species, for example, seem to really like cameras,
so we see them more often than we really should — meaning we might think there are more of that critter than there really are. There are statistical approaches to deal with this kind of bias in the photos, but these statistics are really complex and time consuming.
This has actually sparked a bit of a debate among researchers who use camera traps. Researchers and conservationists have begun to advocate camera traps as a cost-effective, efficient, and accessible way to quickly survey many understudied, threatened ecosystems around the world. They argue that basic counting of photographs of different species is okay as a first pass to understand what animals are there and how many of them there are. And that requiring the use of the really complex stats might hinder our ability to quickly survey threatened ecosystems.
So, what do we do? Are these simple counts of photographs actually any good? Or do we need to spend months turning them into more accurate numbers?
Snapshot Serengeti is really lucky in that many animals have been studied in Serengeti over the years. Meaning that unlike many camera trap surveys, we can actually check our data against a big pile of existing knowledge. In doing so, we can figure out what sorts of things cameras are good at and what they’re not.
Comparing the raw photographic capture rates of major Serengeti herbivores to their population sizes as estimated in the early 2000’s, we see that the cameras do an okay job of reflecting the relative abundance of different species. The scatterplot below shows the population sizes of 14 major herbivores estimated from Serengeti monitoring projects on the x-axis, and camera trap photograph rates of those herbivores on the y-axis. (We take the logarithm of the value for statistical reasons.) There are really more wildebeest than zebra than buffalo than eland, and we see these patterns in the number of photographs taken.
Like we saw the other week, monthly captures shows that we can get a decent sense of how these relative abundances change through time.
So, by comparing the camera trash photos to known data, we see that they do a pretty good job of sketching out some basics about the animals. But the relationship also isn’t perfect.
So, in the end, I think that our Snapshot Serengeti data suggests that cameras are a fantastic tool and that raw photographic capture rates can be used to quickly develop a rough understanding of new places, especially when researchers need to move quickly. But to actually produce specific numbers, say, how many buffalo per square-km there are, we need to dive in to the more complicated statistics. And that’s okay.
You’ve got to check out this game: http://nightjar.exeter.ac.uk/story/nightjar_game
Scientists from the University of Exeter are trying to understand camouflage. Specifically, they want to understand how camouflage helps protect animals from being eaten for dinner, and they’re doing this by studying ground nesting birds in South Africa & Zambia.
Like Snapshot Serengeti, these guys use camera traps too, to figure out whose munching on birds and their nests. Unlike Snapshot Serengeti, however, they aren’t asking for help IDing the photos: instead, they’re asking for help figuring out how predators see, and how different types of camouflage work better or worse against predators with different types of vision.
Humans have trichromatic vision, meaning we have three different types of receptors (light sensitive cells in the eye) that can process color: red (longwave), green (mediumwave), and blue (shortwave). Some animals only have two receptor types and can only see one or two colors, whereas other animals have four, allowing them to see wavelengths such as infrared or ultraviolet that are invisible to people. Thus, what camouflages eggs against one predator might not work so well against another predator.
What these researchers have done is create a game that mimics the vision of other predators. So you get to see the world through the eyes of either a genet cat (with dichromatic vision) or a vervet monkey (with trichromatic vision), and “hunt” for birds or their nests in a series of pictures. This helps scientists understand how perception changes among different animals, and how camouflage works against different perception types.
So go check it out! But don’t forget to come back and then help us classify Season 7! We’ll announce its debut on the blog soon!
Look at this picture of the world – it’s blue, it’s green, it’s dynamic. It is covered in swirling clouds beneath which we can see hints of landforms, their shapes and their colors. Satellites tireless orbiting the Earth gathered the information to construct this image. And every pixel of this this awe-inspiring rendition of our planetary home is packed with data on geology, topography, climatology, and broad-scale biological processes.
I still find it funny that I can sit in my office and watch weather patterns in Asia, cloud formation over the Pacific, or even examine the contours of the moon in minute detail, thanks to remote sensing programs. Not that lunar geomorphology is particularly pertinent to lion behavior, at least, in any way we’ve discovered so far. Still, an incredible amount of information on the Serengeti landscape can be collected by remote sensing and incorporated into our research. “Remote sensing” simply refers to gathering information from an object without actually making physical contact with the object itself. Primarily, this involves the use of aerial platforms (some kind of satellite or aircraft) carrying sensor technologies that detect and classify objects by means of propagated signals. Most people are passingly familiar with RADAR (“radio detection and ranging”) and SONAR (“sound navigation and ranging”), both examples of remote sensing technologies where radio waves and sound, respectively, are emitted and information retrieved from the signal bouncing back off of other objects. The broad-scale biotic or abiotic environmental information gathered can then be used in our analyses to help predict and explain patterns of interest. People are using remote sensing to monitor monitoring deforestation in Amazon Basin, glacial features in Arctic and Antarctic regions, and processes in coastal and deep oceans. Here are brief vignettes of several kinds of remote sensing data we draw upon for our own biological studies.
NDVI: Normalized Difference Vegetation Index
NDVI is collected using the National Oceanic and Atmospheric Administration (NOAA)’s Advanced Very High Resolution Radiometer and is an assessment of whether a bit of landscape in question contains live green vegetation or not. And yes, it’s far more complicated than simply picking out the color “green”. In live plants, chlorophyll in the leaves absorbs solar radiation in the visible light spectrum as a source of energy for the process of photosynthesis. Light in the near-infrared spectral region, however, is much higher in energy and if the plant were to absorb these wavelengths, it would overheat and become damaged. These wavelengths are reflected away. This means that if you look at the spectral readings from vegetation, live green plants appear relatively dark in the visible light spectral area and bright in the near-infrared. You can exploit the strong differences in plant reflectance to determine their distribution in satellite images. Clever, right? NDVI readings are normalized on a scale of -1 to 1, where negative values correspond to water, values closer to zero indicate barren areas of tundra, desert, or barren rock, and increasingly positive values represent increasing vegetated areas. As you can see in the image above, we have NDVI readings for our study sites which can be used to examine temporal and spatial patterns of vegetation cover, biomass, or productivity — factors important in driving herbivore distribution patterns.
MODIS: Moderate-resolution Imaging Spectroradiometer
The MODIS monitoring system is being carried in orbit aboard a pair of satellites, the Terra and Aqua spacecraft, launched by NASA in the early 2000s. The two instruments image the entire surface of the Earth every 1 to 2 days, collecting measurements on a range of spectral bands and spatial resolutions. Their readings provide information on large-scale global processes, including pretty much anything that can occur in the oceans, on land, or throughout the lower atmosphere. Many of the beautiful Earth images, such as the one at the head of this post, are constructed using MODIS data. We hope to use MODIS information for the detection and mapping of wildlife fires, which impact organisms at every level of the Serengeti food web.
LiDAR: Apparently, a common misnomer is that “LiDAR” is an acronym for Light Detection and Ranging, while the official Oxford English Dictionary (the be-all-end-all for etymology) maintains that the word is merely a combination of light and radar. Either way, it’s less of a mouthful than the other two techniques just discussed!
LiDAR is quite well-known for its applications in homing missiles and weapons ranging, and was used in the 1971 Apollo 15 mission to map the surface of the moon. We also use this for biology, I promise. What LiDAR does, and does far better than RADAR technology, is to calculate distances by illuminating a target with a laser and measuring the amount of time it takes for the reflected signal to return. High resolution maps can be produced detailing heights of objects and structural features of any material that can reflect the laser, including metallic and non-metallic objects, rocks, rain, clouds, and even, get this, single molecules. There are two types of LiDAR: topographic, for mapping land, and bathymetric, which can penetrate water. To acquire these types of data for your site, you load up your sensors into an airplane, helicopter, or drone and use these aerial platforms to cover broad areas of land. I first became aware of LiDAR from a study that used this technology in South Africa to map lion habitat and correlate landscape features with hunting success. I’ve also seen it used to map habitat for wolves and elk, determine canopy structure, and, interestingly enough, to remotely distinguish between different types of fish (weird, and also really neat). Now we don’t have LiDAR information for the Serengeti, so keep an eye out for anyone who might be able to lend us a couple of small aircraft and some very expensive sensing equipment!

domain: geography


text:
Showing Collections: 1 - 7 of 7
Abstract This collection is made up of four series that document the day-to-day operations of the College of Architecture as well as the professional work of the Bush-Brown, Gailey, and Heffernan architectural firm, particularly the Tech buildings designed by the firm.
Abstract This collection contains photographs and architectural drawings from the College of Architecture relating to architecture classes and projects as well as materials related to Tech buildings, particularly those designed by Bush-Brown, Gaily, and Heffernan.
Abstract Douglas C. Allen was a former professor of Georgia Tech’s School of Architecture where he worked for 37 years. A specialist in landscape architecture, Allen also participated in several architectural projects in the United States and abroad through various architecture firms. His papers include course materials from his years at Harvard and at Georgia Tech, research and teaching records, documents from his contributions at the architecture firms, and a number of reports about landscape...
Abstract Frank Beckum taught architectural history and drafting in the College of Architecture from 1955 until 1990, serving as Assistant Dean from 1982 until 1990. His papers include course materials from his architectural history classes, primarily lectures and exams.
Abstract This collection contains significant material on Bush-Brown's tenure in the School of Architecture at Georgia Tech as well as the period of his retirement years, particularly the research and writing of his book, Beaux Arts to Bauhaus and Beyond: An Architect's Perspective. Family correspondence, diaries, and Bush-Brown's personal notebooks also form part of this rich collection.
Abstract Series 1 is subdivided into nine subseries: Biographical files; certificates and awards; correspondence; diaries and agendas; education; financial records; home renovation and maintenance and real estate documents; programs and playbills; and travel. The first series richly documents Heffernan's personal life. The series containing P. M. Heffernan's professional papers (SERIES 2) includes a significant amount of material relating to Heffernan's professional life as professor and Director of the...
Overview These records contain the administrative files, annual meeting notes and plans, and publication for the Southeast Society of Architectural Historians (known as SESAH), which is a regional chapter of the Society of Architectural Historians.
- Subject: Architecture -- Study and teaching. X
- Georgia Institute of Technology. College of Architecture 5
- Georgia Institute of Technology. Buildings 4
- Bush-Brown, Gailey, and Heffernan (Architectural firm) 3
- Bush-Brown, Harold 3
- American Institute of Architects 2
- Georgia Institute of Technology. College of Architecture. History 2
- Heffernan, P. M. (Paul Malcolm) 2
- American Society of Architectural Historian 1
- Association of Collegiate Schools of Architecture 1
- Balfour, Alan (Alan H.) 1
- Beckum, Arthur F., Jr. (Arthur Franklin) 1
- Bush-Brown family 1
- Bush-Brown, Henry Kirke 1
- Bush-Brown, James 1
- Bush-Brown, Lydia 1
- Bush-Brown, Margaret Lesley 1
- Bush-Brown, Marjorie Conant 1
- Conant family 1
- Conant, James Bryant 1
- Conant, James S. 1
- Conant, Jennet O. 1
- Craig, Robert 1
- École nationale supérieure des beaux-arts (France) 1
- Fash, William L. 1
- Gailey, James Herbert 1
- Galloway, Thomas D. 1
- Georgia Institute of Technology. Center for Architectural Conservation 1
- Georgia Institute of Technology. Faculty 1
- Hancock, Virginia Heffernan 1
- Harvard University. Alumni and alumnae 1
- Historic American Buildings Survey 1
- Iowa State University. Alumni and alumnae 1
- Iowa State University. History 1
- Kelly, John A. 1
- Myers, John H. 1
- Smith, Joseph N. 1
- Society of Architectural Historians. Southeast Chapter 1
- Templer, John A. 1 ∧ less...

domain: design


Recently, Honda Motor Scooter India (HMSI) was seen overtaking Bajaj to claim the second spot in the sales chart of Indian biking market. It seems like the popular bike manufacturer is all set to get more aggressive with its Indian operations. News has emerged that the manufacturer will be soon seen moving its R&D facility from Gurgaon to its Manesar plant. This is not all as HMSI plans to double the engineers to 200-300 at the R&D dept. once the new facility is functional at Manesar. The Manesar R&D facility should be ready within next 6 months.


IPPR - Government must be bolder on top pay and corporate governance
Mathew Lawrence, IPPR research fellow, responded to today's government announcement on corporate governance reform
"The aim of corporate governance reform should be to tackle the deep-rooted problems in the UK's economic model: low levels of business investment and high levels of pay inequality.
"While welcome, these announcements don't go far enough to address these fundamental challenges.
"The evidence shows there is little correlation between executive pay deals and business performance.
"Consulting workers on executive pay is a good first step but lacks bite; nor is it likely that transparency on pay ratios will be enough to rein in excessive remuneration packages.
"The government needs to be bolder. Rewriting the rules of the firm - expanding who has voice and power within the workplace, and making firms focus on long-term investment - is critical to improving the economy as a whole.
"This is why IPPR's Commission on Economic Justice will be examining a deeper form of corporate governance reform to help ensure the economy works for everyone, not just those at the top."
Kieren Walters 07921 403651 firstname.lastname@example.org
1. The evidence shows there is little correlation between executive pay deals and business performance. In fact only two of the top 10 best paid FTSE 100 CEOs in 2015 made the top 30 in "value for money" rankings of executive pay. https://www.ft.com/content/13fde3b0-871d-11e6-bbbe-2a4dcea95797
2. The IPPR Commission on Economic Justice aims to rewrite rules for the post-Brexit economy. It is a major two-year programme will examine the challenges facing the economy and make practical recommendations for its reform. The Commissioners include the Archbishop of Canterbury, TUC General Secretary, Chairman of John Lewis, CEO of Siemens UK, and many other leading figures.
3. IPPR aims to influence policy in the present and reinvent progressive politics in the future, and is dedicated to the better country that Britain can be through progressive policy and politics. With nearly 60 staff across four offices throughout the UK, IPPR is Britain’s only national think tank with a truly national presence. Our independent research is wide ranging, it covers the economy, work, skills, transport, democracy, the environment, education, energy, migration and healthcare among many other areas. ippr.org
Latest News from
Civitas - Towards Strategic Coherence: Reform proposals following ‘Inadvertently Arming China?’28/07/2021 13:10:00
A Civitas report, Inadvertently Arming China? in February this year revealed the widespread sponsorship of scientific research centres in UK universities by Chinese military-linked conglomerates and universities. It found research at some of these centres is being sponsored by the British taxpayer.
JRF - UK heading for the biggest overnight cut to the basic rate of social security since World War II27/07/2021 12:35:00
JRF issues stark warning to MPs about the looming cut to Universal Credit at the start of the parliamentary summer recess.
Civitas - Curbing of free speech linked to universities with inflated diversity grievance bureaucracies – half of all universities have some form of anonymous reporting service27/07/2021 11:35:00
There is a strong connection between universities with inflated diversity bureaucracies and those that limit speech more generally on campus, researchers at Civitas find in a survey of academic freedom at universities.
'These results should not make for complacency': The King's Fund response to the Office for National Statistics report into ethnic differences in life expectancy27/07/2021 10:35:00
Veena Raleigh, Senior Fellow at The King’s Fund, commented on the Office for National Statistics report into ethnic differences in life expectancy and selected causes of death between 2011 and 2014
Pay is important, but it is not the only factor contributing to high staff turnover: The King's Fund response to the NHS staff 3 per cent pay rise22/07/2021 14:35:00
Richard Murray, Chief Executive of The King’s Fund, commented on the government’s decision this evening to offer NHS staff a 3 per cent pay rise, as recommended by the independent Pay Review Body
IFG - UK government's Shared Prosperity Fund risks damaging trust in union22/07/2021 14:20:00
A new Institute for Government paper warns that the UK government’s post-Brexit UK Shared Prosperity Fund (UKSPF) – replacing EU ‘structural funds’, to be launched in April 2022 – risks damaging trust between the UK and devolved administrations and undermining the UK government’s key objective of binding the four nations of the UK closer together.
IEA expert responds to ONS government borrowing figures21/07/2021 14:20:00
Julian Jessop, Economics Fellow at free market think tank the Institute of Economic Affairs, commented on the government borrowing figures for June published by the Office for National Statistics
IFS - No relief for Rishi Sunak as he prepares for Spending Review: lower-than-expected borrowing likely to prove only temporary21/07/2021 13:05:00
Despite improving public finances this year, the Chancellor is likely to have very little room for manoeuvre in his forthcoming Spending Review. That is because while the economy is recovering more quickly than expected at the March Budget, this may not translate into a permanent improvement in the economic outlook.


text:
Draining of dam stirs up emotions
STANDING next to the now infamous Beehive Dam at Wallangarra, Cr Cameron Gow told the Daily News he didn't want the ping-pong match between councillors and the administration to take away from the real issue at hand.
Cr Gow contacted the Daily News to clarify his stance on the draining of Beehive Dam last week, a development that has triggered a lot of emotions in the southern town of Wallangarra.
"But I don't want the concerns of the Wallangarra community swallowed up by the noise of Ross (Bartley), myself or the CEO of who said who, where and when," he said.
"I never said the councillors didn't know - my comment was that we didn't know the extent of the work involved, which included the full emptying of the dam with all the fish gone.
"More importantly we assumed the local community would be informed and brought along with the issue. The neighbours to the dam weren't even told."
Such was his dismay about the issue, Cr Gow said he had briefly considered not running for council come March.
"I'm going to run, if any reason but to try and make sure something like this doesn't happen again," he said.
"If I can be involved and protect the smaller communities, then all the better for it. I'd love to see smaller communities be treated equally - everyone should be."


Third Place in the AMCC Championships
Penn State Altoona freshman Luke Hoffnagle (Spring Grove, PA/Spring Grove) placed eighth individually out of 45 golfers in the two-day Allegheny Mountain Collegiate Conference Championships on October 8-9. Hoffnagle shot 74 in the first round, then carded a 78 in the second round total 152.
Penn State Behrend 6, Penn State Altoona 1
Senior midfielder Seth Murrelle (Sayre, PA/Sayre) scored his team-leading sixth goal of the season in a loss to AMCC opponent Penn State Behrend on Saturday, Oct. 7.
Penn State Behrend 11, Penn State Altoona 1
Senior forward Shoshana Mahoney (Sweet Valley, PA/Lake-Lehman) added to her team-high goal total in a loss to AMCC opponent Penn State Behrend on Saturday, Oct. 7, scoring her 12th of the season for the Lady Lions.
Washington & Jefferson College 8, Penn State Altoona 1
Freshman Sophia Girol (South Park, PA/South Park) prevailed 7-5, 6-7, 10-8 in her No. 3 singles match on Saturday, Oct. 7, in her team’s loss to non-conference foe W&J.
La Roche College 3, Penn State Altoona 0
Sophomore outside hitter Lauren Diller (Chambersburg, PA/Chambersburg) led Penn State Altoona in kills (7) and total blocks (2) in a loss at AMCC opponent La Roche on Wednesday, Oct. 11.


text:
This is the face of Chicago's Inner-city gun violence victims: a face of elegance, potential, beauty, and ambition. Pryor had a promising future, an Evanston high school graduate, winner of the Mario Tricoci competition, and was someone people praised and enjoyed being around, according to various social media tributes. Say her name.
I was a 14-year-old high school freshman when I began collecting guns. It was Chicago in 1958, a time before a metal detector had ever darkened a school doorway. Disciplinary problems in most American classrooms meant kids sneaking out without a hall pass or sticking old Juicy Fruit under their desks.


text:
The images below tell the story of what I saw as I walked around Tokyo on January 20th, 2015.
This is a yearly personal project inspired by On Taking Pictures #142 (12:18-17:45), Jeffery Saddoris and Bill Wadman discuss "Time Capsule Effect":
And so I did. What follows are the answers to questions that I wrote to myself a year ago and can now answer.
What did you do on this day?
I set out with my camera to document what I saw on a single day to see how those images would feel after a year of not looking at them. I covered about 22 kilometres of Tokyo on foot, walking through some of my favourite areas: Shinjuku, Meiji shrine, Omotesando, Tokyo Station, Yurakucho, Ginza, and Shinbashi.
Where did the inspiration for this come from?
A conversation between Bill Wadman and Jeffery Saddoris, you can see it above. That episode aired on January 13, 2015 which is only a week before my birthday. So I figured doing it on my birthday would add something to the experience, which it did. In the long run I think it will be interesting to have a visual record of what I saw on this day.
Was there a difference in your shooting style versus your day to day style?
I had some ground rules: just me, my camera & my journal / no peaking / no chimping / no spraying / no looking at the photos until a year later. One thing that I took away from that day was being more observant of my surroundings, the people who may walk into the scene in a few moments, or the look of a scene, looking more for colours and patterns. Looking at the photos I took on this day I can see I was heavily influenced for the remainder of the year. This one day really influenced me to be more observant and to take my time a bit more, something that I carried with me for the rest of the year.
What did you shoot?
I shot my typical urban photography style, storefronts or the street with a single person or small group. There were some nature abstracts, which I will probably make a small series with later on. I photographed people, places, construction that was going on, and some graffiti much of which is also now gone, but I have a record of it. I didn't set out with anything in mind, I just wanted to see what I would find.
How do you feel about the photos a year later?
There was a point last year when I was searching through my images for a photo, one I was sure that I had taken, but I couldn't find it. After a while I clued in that I had probably taken it on this day, and sure enough the other day when I finally looked I found it (the above shot that has a neon sign that says "Apple Inn". I thought that I would have forgotten about the images, but really I think they stuck with me more than my day to day photography and influenced what I shot for the remainder of the year. The bad images have no more staying power than any of my other bad images, I knew some would be out of focus or I missed the chance just barely, they are still failures to learn from. In all I took 128 pictures that day, which is a lot more than I normally take, as I went through there were 20 that I quite enjoyed, and I found a common theme among those.
Would you do it again?
I already have! I set out on my birthday again this year and followed the same rules I set in 2015. I didn't cover as much ground as the previous year, nor did I take as many photos, the weather was terrible but I was determined to do it again. As long as I am able, I will continue doing this on my birthday, a small gift to myself.


Samsung is gearing up for an unexpected revival of its Galaxy Tab S6 Lite, introducing a 2024 refresh that has caught the attention of tech enthusiasts. Emerging from the shadows of online certifications and benchmarks, this new iteration, known as the Galaxy Tab S6 Lite (2024), showcases Samsung’s commitment to updating its more budget-friendly offerings with contemporary tech enhancements.
With model numbers SM-P625 and SM-P620 hinting at 4G and Wi-Fi versions respectively, the updated Galaxy Tab S6 Lite is speculated to feature the Exynos 1280 chip and Android 14, marking a notable upgrade from its predecessors. The original Tab S6 Lite, launched four years ago with the Exynos 9611 chip and Android 10, received its first refresh in 2022, which included newer chips and Android 12. This pattern of biennial updates suggests Samsung’s strategy to keep its mid-range devices relevant in a fast-evolving market.
The 2024 Galaxy Tab S6 Lite maintains the popular design of its predecessors. It features a 10.4-inch LCD with a 2000 x 1200-pixel resolution and slim bezels, providing an immersive viewing experience. The tablet comes in Oxford Gray, Chiffon Pink, and Mint color options. Like previous models, the S Pen stylus remains included for drawing and note-taking.
The Samsung Galaxy Tab S6 Lite (2024) retains a substantial 7,040mAh battery which promises up to 14 hours of video playback. The tablet will be available for purchase starting March 28th, 2024. While Samsung has yet to announce official pricing, expectations are that the updated model will stay competitive with its predecessors.
Camera capabilities remain unchanged, with an 8MP rear-facing camera and a 5MP front-facing camera. Samsung offers the tablet with either 64GB or 128GB of internal storage, expandable up to 1TB via a microSD card. Users can choose between Wi-Fi-only and LTE-enabled models for greater connectivity
While specifics about improvements beyond the OS and chip upgrade remain scarce, the mere fact of another refresh points to a strategy aimed at offering value to consumers looking for an affordable tablet with S Pen compatibility. Additionally, rumors swirl around a potential simultaneous refresh of the Galaxy Watch 4, indicating Samsung’s broader strategy to update its wearable and tablet offerings in tandem.
As anticipation builds, the Galaxy Tab S6 Lite (2024) refresh represents a potentially compelling option for budget-conscious consumers seeking the latest software and improved hardware without breaking the bank. However, the final judgment will depend on its price point and how it stacks up against the competition upon release.


text:
Best Resort Near Pune
I dont have a word to say anything. Everything was just awesome. All the management, location, spots, staying facility, food is A class. The best thing is the owner itself look into the matter. Best couple very down to earth people. We had our marriage here and we have best memories of our life. Thank you to Mr and Mrs Pawar and all the staff members of Pawar Agro Resort. Thank you once again.
stay with clean room and calm environment
I really enjoyed the stay with clean room and calm environment. You maintain the premises properly which is really appreciated. I like the food and other services. Overall stay was very good, highly recommended and looking for my next visit.
Best destination for wedding near pune
Best destination for wedding.Awesome food and good services..best resort we ever visit. We definiatly recommend to my friends and others.....excellent services.
Nice place for enjoy with your family near pune
Nice place for enjoy with your family. Also you can make your day by arranging get together, function, marriage & birthday celebration. Also u can enjoy rain dance, swimming, boating & many physical activity. Food also good quality. Most important is night stay facility available for 40 people. We got good experience by spending time over there.
Best resort in and around Pune
Pawar Agro resort is one of the coolest resort in and around Pune. They have well maintain villas which can host a group. The rooms are clean, very well maintained. It has lots of amenities to Enjoy and play around including cricket, swimming pool, DJ and more. It has its restaurant which prepares delicious homely food.
Loved the hospitality
Loved the hospitality of Pawar family. All staff members are also extremely courteous and you would definitely feel at home away from home. Very nice place for family outing in the lap of nature.

domain: travel


Check out all the latest podcasts including Blinkers Off and The Magic Mike Show
Check out all the big upcoming stakes races
LOUISVILLE, KY – Pop a Top LLC’s homebred Beyond Blame made a furious rally to win Saturday’s Grade 3, $100,000 Regret Stakes at Churchill Downs. The Regret was race 9 on […]
ARCADIA, CA – Coming from the back of the pack to win it, Paved proved herself by winning Saturday’s Grade 2, $200,000 Honeymoon Stakes at Santa Anita Park. This was the […] Read More
ARCADIA, CA – Allen Racing and Bloom Racing Stable’s Midnight Bisou scored her third straight stakes victory in gallant style, effortlessly winning Saturday’s Grade 1, $400,000 Santa Anita Oaks. Breaking well from […] Read More
The Racing Dudes preview and give picks for Monday’s $500,000… Read More
The Magic Mike Show guys preview & give their tickets… Read More
Aaron and Papa Dude get serious this week, exploring and… Read More
The Racing Dudes preview and give picks for Saturday’s $1.5… Read More
Aaron previews the 2023 Shoemaker Stakes (G1) from Santa Anita… Read More
Aaron previews the 2023 Hollywood Gold Cup (G1) from Santa… Read More
Aaron previews the 2023 Gamely Stakes (G1) from Santa Anita… Read More
Mike previews the 2023 Winning Colors Stakes (G3) from Churchill… Read More
Looking to cash in big?
Sign up for exclusive 10% discount on orders, plus be the first to access our daily free and premium horse racing picks, articles, podcasts, and more!


text:
was a composer and instrumentalist of music Portuguese extraction who pursued his. Enrique Iglesias: Hero for voice guitar, piano intermediate sheet music. Includes an High Quality PDF file to download piano instantly. , resident says his care. Recently the Berkley Mass.
Concert Posters and Music Memorabilia. Free Hero piano sheet music is provided for you. Learn this song on Jellynote with our interactive sheet music and tabs. Shop the World' s Largest Sheet Music Selection today enrique at Sheet Music Plus. High Quality piano play along hero hero , , piano easy hero practice by changing the tempo, Interactive, hero transposable in sheet any key more. Subtitled Films: Sorted by Title This list contains all of our english- enrique subtitled films and is updated quarterly. For newer titles, please use the library catalog. Play along with youtube video covers.
Buy Sell or Trade your concert memorabilia. Search our free piano sheet music database for more! In the last year, he’ s enrique been in the hospital four times. 1- 20 of hero 122 Rock Pop Guitar Sheet Music, Chord Charts, Lessons Resources ( search within these results). Venue and Graphic Artist information for collectors. Free PDF Piano Sheet Music for " Tired Of Being Sorry - Enrique Iglesias".
trugest enrique price Medicare beneficiary piano James Conway has high blood pressure, a catheter that has led to several urinary tract infections , 73 a condition that hero causes spinal fluid to build up in the base of his skull. Piano Tutorials and Sheet Music. piano record label Fonovisa Records in the mid- enrique 1990s using the name Enrique Martinez. legal description for sheet one licensed to dispense prescription drugs The Model S is enrique the best- selling U. Hero is a single released by Enrique Iglesias from his second enrique English album Escape was written by Iglesias, Paul Barry Mark Taylor. Enrique hero piano sheet music.
Music Chart I am looking for hero a particular song, how can I find it? Hero digital sheet music. The hero company sold piano 5 150 cars in the second quarter , said on Wednesday it expects to reach an annual production rate of 40, 000 by late next year as it starts selling in Europe Asia. Archival database of Rock Jazz, Soul posters, tickets, Bluegrass, Hip- Hop, Country Punk, Jamband flyers. Where are you calling from? Enrique Iglesias enrique Piano Tutorials and Sheet Music. electric car despite a starting price of more than $ 70, 000. VIEW: BLU- RAY - DVD BLU- RAY.
Contains enrique printable sheet music plus an interactive, downloadable digital sheet music file. Hero - Enrique Iglesias - free chords and lyrics.
This is a list of public domain compositions that feature the cello and that have been uploaded to IMSLP. These include cello solo works, cello sonatas, cello concertos, transcriptions and even chamber music pieces that feature the cello. Enrique Iglesias - Hero sheet music for Guitar View this Riff To view this riff select Riff Lesson from the tabs below. Enrique Iglesias Music - Download Sheet Music PDF - Printable.
enrique hero piano sheet music
View all Big Note Piano. Oct 24, · Rick Astley - Never Gonna Give You Up ( Official Video) - Listen On Spotify: it/ AstleySpotify Learn more about the brand new album ‘ Beautiful.

domain: entertainment


text:
Looking for a low VA loan refinance rate?
If you’re a veteran or military personnel who currently has a VA mortgage loan, a new VA loan refinance choice could help lower your payment. A VA Streamline Refinance is a refinance option for current VA mortgage holders to lower their interest rate with minimal or no out-of-pocket costs.
A VA streamline refinance loan (IRRRL – Interest Rate Reduction Refinancing Loan) is done easily and can help veterans and military personnel start saving on their mortgage immediately, but it is only available to veterans/active service personal who used their VA eligibility when initially purchasing their home.
Email Questions to email@example.com or request a free comparison of your current loan next to the new 15 or 30 year Fixed rate options.
Benefits of a VA streamline refinance:
- Standard underwriting process is omitted – no need to send in bank statements, W2s, job verification, paychecks, etc.
- No appraisal required in most cases
- No Out of Pocket Costs in most cases
- Skip up to two monthly payments+
- Ability to receive your past loan escrow account balance back from previous lender
- Ability to finance Energy Efficient Improvements into the loan
What is a VA Streamline Refinance (IRRRL)?
An IRRRL is the VA’s Interest Rate Reduction Refinancing Loan program and is referred to as a VA Streamline Refinance or “VA to VA Refinance”. With this loan, you refinance your existing VA mortgage into a new VA loan with a lower interest rate. Or if you have an adjustable rate mortgage you can replace it with a fixed rate loan. You can also select to shorten your term to a 15 year Fixed rate and build equity faster.
Do I have to be eligible for a lower interest rate in order to qualify for a VA Streamline / IRRRL?
Usually yes, unless you have an adjustable rate mortgage. In order to qualify for an IRRRL, the VA requires that if you already have a fixed rate you should only refinance to a lower rate. But if you have an ARM (adjustable rate mortgage) you can refinance to a fixed rate even if it doesn’t lower your interest rate.
Why would the VA allow me to get a higher rate if I have an adjustable rate mortgage right now?
With adjustable rate mortgages you may have an initial lower interest rate than a fixed rate mortgage for the first few years, but after the initial period your interest rate will adjust and you could be paying higher payments than you would with a fixed rate mortgage. The VA recognizes this and wants to encourage stability.
Must I use my current lender to refinance?
No. You can choose from any mortgage lender on the VA approved lender’s list. Make sure that you shop around for your VA streamline refinance. By researching several lenders you will get more offers and you can choose the best loan terms for you and your family. Be careful of lenders that try to deceive you into thinking they are the only lender that can finance a VA streamline refinance. The VA has a long list of approved lenders and you should shop around.
Call Josh Campbell at 972-904-3694 or email firstname.lastname@example.org – Josh is in Texas and serves all 50 States
Does the VA have any requirements for me to get a VA Streamline Refinance / IRRRL?
You must be refinancing an existing VA-backed loan into a new VA-backed loan in order to use this program. You cannot receive any cash at closing. The loan amount can only increase slightly as a result of fees and closing costs being financed into the mortgage. However, with a low cost lender such as Josh Campbell, there should be no trouble making sure there is very little out of pocket costs.
Do I have to go through a credit check and appraisal process again when refinancing?
The VA does not require this, because they have already approved you for the loan when you bought the house. However, some lenders usually do require a credit check to make sure there are no new judgments or mortgage delinquencies which could disqualify you from being eligible for a VA streamline refinance.
Do I have to get another Certificate of Eligibility?
NO – Since you already provided this when you bought the property, no additional proof of a Certificate of Eligibility is needed.
How can I refinance if I am using my eligibility already on my current loan?
As long as you are refinancing your VA-backed mortgage you can use this program to get more favorable loan terms. Since this is a VA refinance, you do not need to provide your Certificate of Eligibility again.
What out-of-pocket expenses will I have when streamline refinancing?
None. VA allows all closing costs of refinancing to be financed into your new mortgage. Your lender may have some fees, but you will need to ask to find out what they expect you to pay out of pocket, if anything.
What fees does the VA charge for a streamline refinance?
The VA only requires a nominal funding fee of the amount of your new loan. There are no other fees involved with the VA.
I am exempt from paying the VA funding fee. Does this apply on an IRRRL?
Yes. As long as you are still classified as 10% disabled or more you should be exempt from any of the VA’s funding fees.
Can I include the cost of home improvements in my IRRRL?
You are allowed to include up to $6,000 in your refinancing loan for the purpose of energy efficient home improvements. Any other home improvements are not eligible.
Can I take cash out with a VA streamline refinance?
No. An IRRRL from the VA is only for the purposes of receiving a better interest rate on your mortgage loan in order to save you cash over the life of the loan.
What is a VA Cash-Out Refinance Loan?
This is the type of refinance that the VA offers for those veterans who want to take cash out of the equity in their homes. You must be refinancing an existing VA loan in order to use the VA cash-out refinancing program.
Can I convert from a conventional loan to a VA Loan?
Yes, eligible veterans who currently have a conventional loan can still look at refinancing into a VA loan. This is not the same as the VA streamline refinance mentioned elsewhere. If the circumstances are favorable, the borrower can use their VA eligibility to refinance.
If the borrower has an adjustable rate mortgage (ARM) or a high fixed interest rate, then converting can be worth looking into. The biggest hurdle in changing to a VA loan is there is the VA funding fee of 2.2% on this type of refinance. However, if the borrower is exempt from the VA funding fee this can make the refinancing even more lucrative.
Email questions or request a FREE consultation with Josh Campbell at email@example.com or complete the short form below.

domain: economics


Stephen Baldwin would like to step into the ring for a boxing match with US Presidential candidate Barack Obama.
The actor is a supporter of Republican nominee John McCain and has told the New York Daily Times that he will leave the country if Obama is elected next month.
"I'd like to knock some good sense into Barack. I wouldn't hurt him. But if he wins the election, he'll hurt me. He's a cultural terrorist," said Baldwin.
Earlier this year, Baldwin attacked rock star Bono for his attempts to ease third world debt.
He told WENN that it would make more sense to preach the gospel of Jesus abroad.


Vivo Y15 Price In Pakistan: What Makes This Smartphone Unique
The display screen on the Vivo Y15 measures 6.4 inches and uses IPS LCD technology. The display panel has a resolution of 720 x 1544 pixels, which is HD+. The phone’s waterdrop notch houses the front-facing camera. The handset will have thin bezels on three sides and a thicker bezel at the bottom. The phone will be offered in two colour options: Mineral Blue and Mystic Purple.
In terms of performance, the Vivo Y15 is equipped with a Helio P22 SoC and 4 GB of RAM, allowing for swift multitasking. The phone has 64 gigabytes of internal storage and a microSD card slot for memory expansion. This means you won’t have to worry about running out of storage space for your apps, photos, and videos.
But what truly distinguishes the Vivo Y15 from other entry-level smartphones is its camera configuration. The triple rear camera system on the new Y15 consists of a 13-megapixel primary sensor, an 8-megapixel secondary sensor, and a 2-megapixel third sensor. This allows you to take photographs with incredible depth and detail. The lens on the selfie camera is 20 megapixels, allowing you to take excellent selfies with ease.
The phone’s fingerprint sensor, which is located on the device’s rear, provides reliable security. Although the Y15 will not have an in-display fingerprint scanner, the rear-mounted scanner is still an excellent option. In addition, the phone’s 5000 mAh battery provides sufficient power for the smartphone.
The Vivo Y15 is an impressive entry-level smartphone that will make its mark on the market. It is an excellent choice for those on a budget due to its large screen, potent performance, impressive camera setup, and dependable security features. The Vivo Y15 will impress whether you’re browsing social media, streaming videos, or taking photos. Therefore, if you’re in the market for a new phone, the Vivo Y15 is an excellent option to consider.


With ultra-short throw and a wide lens-shift range, our revolutionary compact, large-screen projectors offer more ways to create a sense of space.
Both projectors feature a FUJIFILM unique folded lens. Bending and focusing light to create an image requires a high-precision optical design. By utilizing the optical design software originally developed by FUJIFILM, dozens of elements were combined to create a lens that can be rotated without creating distortion and that projects a high-quality image to every corner of the screen.
Maintaining high resolution without distortion requires precise alignment of the optical axis. Multiple adjustments are optimally combined to deliver a high-quality image.
We overhauled the color design of the Z-projector to increase the color space. The projector boasts a wide variety of customizable controls - including settings for hue, saturation, color temperature, and seven-color tuning - that combine with edge blending to allow images to be displayed effectively using multiple projectors.
The front lens group (Group G1) features a wide-diameter aspherical lens. It is to this wide(87mm)aspherical element with a surface ground to high-precision, single-micron tolerances, that the projector owes its ultra-short throw.
- High Resolution, High Quality
- High-Precision Optical Axis Alignment
- Improved Color Reproduction for More Vivid Colors
- Large Screen, Ultra-Short Throw
- 100" Images from Ultra-Close Range
- Wide Lens-Shift Range
- An Ultra-Short Throw Combined with a Wide Lens-Shift Range
- Compact Design with a Built-in Lens


A 12 volt solar fence charger is an economical and environmentally-friendly way to power an electric fence. This type of charger uses solar panels to convert sunlight into electricity, which is then stored in batteries. When the batteries are full, the charger will automatically shut off.
Are you looking for a way to keep your livestock safe and your property secure? If so, you may be wondering if a 12 volt solar fence charger is right for you. Here are a few things to consider that can help you make your decision.
Benefits of a 12 Volt Solar Fence Charger There are many benefits to using a 12 volt solar fence charger. One of the biggest benefits is that it is environmentally friendly.
You don’t have to worry about the charger harming the environment because it doesn’t use any harmful chemicals or produce any pollution. Another great benefit of using a 12 volt solar fence charger is that it is very easy to install. You don’t need to hire an electrician to come out and install it for you.
You can simply follow the instructions that come with the charger and install it yourself. Lastly, a 12 volt solar fence charger is a great way to save money. You won’t have to worry about your electric bill going up because you are using solar power.
Solar power is free once you have the initial investment of the charger. Things to Consider Now that you know some of the benefits of using a 12 volt solar fence charger, you may be wondering if it is right for you.
Here are a few things to consider that can help you make your decision. First, you need to think about the size of your property.
Parmak 12 volt solar fence charger
If you’re looking for a powerful and reliable solar fence charger, the Parmak 12 volt solar fence charger is a great option. This charger is designed for use with 12 volt batteries, and it features a built-in solar panel that charges the battery while it’s in use. The Parmak 12 volt solar fence charger also features a built-in digital display that shows the battery’s charge level, so you can keep an eye on it while it’s working.
How many volts should a solar fence charger put out?
The output of a solar fence charger is determined by the manufacturer and is typically between 3,000 and 6,000 volts. The voltage output can be increased by adding more solar panels to the charger.
What is the best solar electric fence charger?
If you are looking for a reliable and affordable solar electric fence charger, the Zareba ESP5M-Z Solar Powered 5-Mile Low Impedance Fence Charger is a great option. This charger is designed for use with livestock fences, and it can power up to 5 miles of fence. It is made with a durable and weatherproof casing, and it includes a built-in battery that will keep the charger running for up to 7 days without sunlight.
The Zareba ESP5M-Z Solar Powered 5-Mile Low Impedance Fence Charger is a great option for those who are looking for a reliable and affordable solar electric fence charger.
How long does a solar fence charger battery last?
Solar fence chargers are a great way to keep your fence charged without having to worry about a power outlet. But how long do they last?
Most solar fence chargers have a built-in battery that will last for several years with proper care.
However, the battery life will vary depending on the brand, model, and how often it is used. To get the most out of your solar fence charger, it is important to follow the manufacturer’s instructions for care and maintenance. This includes charging the battery regularly and keeping it clean.
If you take good care of your solar fence charger, it should last for several years. However, if you neglect it, the battery life will be shortened.
What size solar fence charger do I need?
When it comes to choosing a solar fence charger, size does matter. But with so many different sizes and options on the market, it can be tough to figure out which one is right for your needs.
Here are a few things to keep in mind when choosing the size of your solar fence charger:
1. The size of your fence. This is probably the most important factor to consider when choosing a solar fence charger. The larger your fence, the more powerful the charger will need to be in order to adequately cover the entire area.
2. The number of animals you have. If you have a lot of animals, they will likely require more power to keep them contained. A larger charger will be able to provide that extra power.
3. The type of animals you have. Some animals are more difficult to contain than others. If you have particularly pesky critters, you may need a more powerful charger to keep them in check.
4. The climate you live in. If you live in an area with lots of sun, you’ll likely need a smaller charger. But if you live in a cloudy climate, a larger charger will be necessary to capture enough solar power.
5. Your budget. Of course, cost is always a factor to consider. But it’s important to remember that you get what you pay for.
Parmak Solar Pak 12 or Solar Pak 6 Test & Overview, send it here for repair, www.fencerfixer.com
If you are looking for an electric fence charger that is powered by solar energy, then you may want to consider a 12 volt solar fence charger. These types of chargers are designed to be used with 12 volt batteries, and they can be a great way to save money on your electric fence operating costs. In addition, solar fence chargers are typically very easy to install and maintain, making them a great option for those who do not want to deal with the hassle of traditional electric fence chargers.


text:
Resveratrol plays dual roles in pancreatic cancer cells
- 777 Downloads
Although the potential anticancer effect of resveratrol (RSV) on pancreatic cancer has been reported, its mechanism was not fully understood. The role of vascular endothelial growth factor B (VEGF-B) in cancer remains controversial. Herein, we aimed to examine whether the anticancer effect of RSV was related to the VEGF-B.
The effect of RSV on pancreatic cancer cell line (capan-2 cells) was evaluated by CCK-8 assay, Hoechst 33342 staining, and flow cytometry. The mRNA level of VEGF-B was measured by real-time PCR. VEGF-B expression was knockdown by small interfering RNA (siRNA).The protein levels of VEGF-B, glycogen synthase kinase-3 beta (GSK-3β), and Bax were measured by Western blot.
Resveratrol treatment inhibited tumor growth, induced apoptosis, and up-regulated Bax expression in capan-2 cells. The mRNA and protein levels of VEGF-B were up-regulated after RSV treatment. However, VEGF-B siRNA treatment increased the apoptotic rate, and inhibited tumor activator GSK-3β, while Bax expression was not affected. The combination of RSV and VEGF-B siRNA showed significantly higher apoptotic rate in comparison with RSV or VEGF-B siRNA mono-treatment group.
Resveratrol plays dual roles in pancreatic cancer: as a tumor suppressor via the up-regulation of Bax; as a tumor activator via the up-regulation of VEGF-B; and the anticancer effect of RSV is much stronger than the cancer promotion effect. The combination of RSV with pharmacological inhibitor of VEGF-B might, therefore, be a promising modality for clinical pancreatic cancer therapy.
KeywordsResveratrol VEGF-B Tumor apoptosis Pancreatic cancer
This research was supported by the National Natural Science Foundation of China (No. 81201206), the Natural Science Foundation of Tianjin (No. 11JCYBJC10000), the Research Fund for the Doctoral Program of Ministry of Education of China (No. 20120031120058), the National Natural Science Foundation of China (No. 81101222), and Science Foundation of Tianjin Medical University (No. 2010ky16). The authors thank Pro. Yang Wang, Zhiping Xie for providing us instruments, and also thank Ms. Nancy Bai for the careful language correction.
Conflict of interest
We declare that we have no conflict of interest.
- Albrecht I, Kopfstein L, Strittmatter K, Schomber T, Falkevall A, Hagberg CE, Lorentz P, Jeltsch M, Alitalo K, Eriksson U (2010) Suppressive effects of vascular endothelial growth factor-B on tumor growth in a mouse model of pancreatic neuroendocrine tumorigenesis. PLoS ONE 5:e14109CrossRefPubMedPubMedCentralGoogle Scholar
- Cho IR, Koh SS, Malilas W, Srisuttee R, Moon J, Choi YW, Horio Y, Oh S, Chung YH (2012) SIRT1 inhibits proliferation of pancreatic cancer cells expressing pancreatic adenocarcinoma up-regulated factor (PAUF), a novel oncogene, by suppression of β-catenin. Biochem Biophys Res Commun 423:270–275CrossRefPubMedGoogle Scholar
- Gunningham SP, Currie MJ, Han C, Turner K, Scott PA, Robinson BA, Harris AL, Fox SB (2001b) Vascular endothelial growth factor-B and vascular endothelial growth factor-C expression in renal cell carcinomas regulation by the von Hippel-Lindau gene and hypoxia. Cancer Res 61:3206–3211PubMedGoogle Scholar
- Takaoka M (1940) Of the phenolic substances of white hellebore (Veratrum grandiflorum Loes. fil.). J Fac Sci Hokkaido Imp Univ 3:1–16Google Scholar

domain: medical


Tender melodic piano moves slowly amongst delicate strings and subtle guitar.
Select film genres to refine your search
Select from tracks we have specially chosen as great for trailers
Choose a tempo from the presets or enter your own
Your account is still pending approval.
For immediate assistance, please email email@example.com.


text:
Dirty Harry's Peak
Recent trail work in the summer of 2018 makes this peak a great close-to-Seattle day hike in a few hours and a good alternative hike to Mount Si.
This is a difficult out and back trail to Dirty Harry's Peak in Middle Fork Snoqualmie Natural Resources Conservation Area.
Share the trailhead and beginning of trail with rock climbers looking for a day of cragging.
This trail goes by The Grit Scone, Overhaul, Truck Town, Truck Town Cave, Sun Vista Slab, The Cirque, Interstate Park, Dirty Harry's Rest Stop, Headlight Point, Squishy Bell, Eastern Block, Winter Block, and Dirty Harry's Balcony.
After passing the popular climbing turn-offs, follow the signs along the trail. Pass a short junction off the right for the Little Balcony. From the balcony, the trail starts to climb steeper up an old mining road. Hang in there as you'll be rewarded with views of Mount Rainier and Mount Baker.
A Discover Pass is required to park at the trailhead. You can purchase a day-use pass at the parking lot or consider buying an annual permit.
The hike includes steep terrain and cliff areas that could be dangerous for children.
Rate this Hike


“For the next game, you need to name FIVE French Montana songs without features,” user @sticktalkz tweeted alongside an image of the red guards from the Netflix series.
After French caught wind of the tweet, he fired back, listing 14 of his solo songs, including “Ain’t Worried About Nothing,” “Sanctuary,” and “F*ck With Me Get Bag.” He ended the tweet by saying, “Now eat a d*ck. I’m droping [sic] a solo track this week.”
This isn’t the first time French has had to defend himself against his critics. Last year, he claimed that he could go “neck to neck” with Kendrick Lamar. “Most of kendricks features Too!” Montana commented in response to those saying that all his hits have features. “I never compared myself I just stood up for myself. we all know kendrick one of the goats,” he added.
French later appeared on Everyday Struggle to state his case, saying that he was purely defending himself. “I never knew that standing up for yourself wasn’t cool no more,” he said. “People was acting like I said something wrong.”


text:
HOLBROOK — As COVID cases inch upward, Navajo County health officials have renewed their call for people to stay home if they feel ill and wear masks in public when they do venture out.
“We continue to see a rise in cases and our partner healthcare facilities are starting to see an increase for both flu and COVID,” said Navajo County Public Health Director Jeff Lee at this week’s board of supervisors meeting.
“Overall in Navajo County, we’ve done a good job of following the CDC recommendations — but we’ve let our guard down a little and now we have to do better,” said Lee.
Statewide, COVID cases have increased by 46% in the past two weeks and hospitalizations have increased by 21%, according to national databases. Deaths have actually decreased by 13% in that period. That’s partly because death rates generally lag a month behind infection rates. However, improved treatments in hospitals have also cut the death rate for the most seriously ill.
In Navajo County, the case count has surpassed 6,300. In the past week, the 210 new cases represent an infection rate of 189 per 100,000.
In Apache County, the total number of infections has passed 3,885. In the past week, the 104 new cases represent an infection rate of 145 per 100,000.
Both Navajo and Apache counties have infection rates well above the state average of 100 per 100,000. However, they’re doing better than the current hotspots – including Greenlee, Graham, Coconino and Gila Counties.
Both Navajo and Apache Counties are wobbling when it comes to meeting the state’s benchmarks for school openings, which include infection rates, the percentage of positive tests and hospital visits.
Navajo County remains below the threshold in all three categories — but has been drifting upward according to the State Department of Health Services website. However, those posted figures date back to the week ending Oct. 4. The odds are the county has since broken the barrier for even “moderate” spread.
Apache County’s doing even worse. As of Oct. 4, the county no longer met the infection rate threshold for even hybrid school reopening, based on “moderate” spread of the virus in the community. The state department of health services showed the county also poised to cross into the “widespread” category for the percentage of positive tests. The hospitalization numbers remained below the threshold for minimal spread – at least based on the week ending Oct. 4.
In Navajo County, several schools have reported cases, with substantial exposures of children on campus. The St. Johns School District has had positive cases that exposed 100 students and staff to the virus and is weighing whether to shut down at least for a time next week.
Moreover, county health workers have been finding an increasing number of workplace clusters.
“We are linking many cases back to a situation in which someone went to work when they didn’t feel well and it ended up being COVID — and they spread COVID throughout that workplace,” said Lee.
So stay home if you don’t feel right — and make sure to wear a mask when you can’t socially distance out in public.
“We need to socially distance not only in public — but at work,” said Lee. “We’re finding more and more situations where people are not following those guidelines as closely as they have in the past.”
Moreover, people seem increasingly reluctant to help health officials by identifying all their close contacts, which remains crucial to containing outbreaks and growing clusters of cases.
“We’re starting to experience more and more situations where we have confirmed, positive cases that aren’t willing to share the information we need to break the chain of transmission,” said Lee.
The precautions can slow the spread of the virus until a vaccine is approved and distributed.
Lee noted that the county meets with doctors and hospitals several times each week to work out the plans to vaccinate as many people as possible once the vaccine is cleared for public use in the U.S. He hopes that will come before the end of this year, but if issues arise in the phase III clinical trials for several vaccines, the vaccine may not become available until next spring.
“We’re working very closely with our state and local partners to make sure that when the vaccine is available, we have our process in place so we can deploy the vaccine to our communities,” said Lee.
“The timing of the vaccine is unknown right now. There is a possibility it will be available by the end of the calendar year — and that’s what we’re planning for. But that’s based on the successful vaccine trials continuing. If there are any hiccups, it will push the date back further.”
About half a dozen vaccines are currently in the midst of phase III clinical trials, testing both whether the vaccine can prevent or soften an infection and whether the shots might cause rare adverse reactions that would only show up in trials with 20,000 or 50,000 people. Several vaccine trials have been paused — then mostly restarted — after someone in the trial developed possible side effects. It is common to stop and start such trials to investigate such cases. Often, the problem proves completely unrelated to the vaccine.
Historically, it takes 5-10 years to develop a safe, effective vaccine against a virus. For instance, researchers still haven’t developed a vaccine that will prevent infection with the AIDS virus. However, the billions of dollars invested in the search for a COVID vaccine could well produce results in just a year from the onset of the pandemic.
Russia has already started distributing a vaccine without completing Phase III trials. China is reportedly closer to approving a vaccine than the US.
Lee noted that hospitalizations have begun a worrisome rise once again and doctors, nurses and other healthcare professions continue to struggle with a shortage of gloves.
Statewide as of Oct. 22 some 83% of the state’s adult intensive care beds were in use, but COVID patients accounted for only 11% of the hospitalizations. The situation has improved since mid-July, when 92% of the intensive care beds were in use, with COVID patients account for 57%. Still, the total number of beds occupied and the share of COVID patients has been inching upwards steadily since late September.
Fortunately, Lee said the county has enough test kits on hand that anyone who wants a COVID test can get one. He said doctors, hospitals and clinics are also working to obtain new tests that can yield a result in 15 minutes. The tests aren’t as accurate as the nose-swab test. But they’re better for rapid screening in places like schools and in trying to pinpoint clusters, since it can take two days to a week to get results for the swab tests from a laboratory.
National studies and epidemiological models suggest the US tests a much lower share of its population than countries that have gotten the pandemic under control. Throughout most of the pandemic, the US has focused on testing people with symptoms while people without symptoms or a documented exposure to a positive case have more trouble getting tested. Studies suggest widespread, rapid testing remains one of the keys to preventing the development of clusters of cases that seem to be driving the pandemic.
One study found that the pandemic has been driven by “super spreader” events, perhaps because perhaps 30% of those infected never develop symptoms and never realize they’re spreading it. The virus seems to spread mostly through the air during close contact, especially when people are crowded together, talking loudly and not wearing masks.


A Sports Utility Vehicle (SUV) on Wednesday, ran into a crowd of #ENDSARS protesters at Alagbado, a Lagos suburb, reportedly killing two persons and leaving others injured.
A video sighted by Naijakit on the micro-blogging site, Twitter,showed two lifeless bodies being carried away by some #ENDSARS protesters in the area. After the sad incident, a volunteer of medical corps was deployed, especially around Amikanle area to take care of the wounded before those with severe injuries were moved to Cavesbury Hospital.
Reports by eyewitnesses, say silver SUV deliberately ran into the protesters in a bid to scare them off the road, a development which saw an angry mob descend on the SUV as well as a tricycle involved in the accident.
As at the time of filing this report, the driver of the vehicle was yet to be identified.
Meanwhile, the Federal Government led by President Muhammadu Buhari, may forcefully end the ongoing #EndSARS protests across the country, the Chairman of the Presidential Advisory Committee Against Corruption (PACAC), Prof. Itse Sagay has said.
NaijaKit reports that protesting youths in Nigeria agitating for the end to Police brutalization and extra judicial killings of Nigerians. The protesters have been on the streets for six days now, protesting the brutalities, humiliation, and extortion of Nigerians, especially the youths.
The protesters demanded an end to the Special Anti-Robbery Squad (SARS), a police unit under the Force Criminal Investigation and Intelligence Department headed by the Deputy Inspector General of Police Anthony Ogbizi, using a hashtag: #EndSARS.
On Sunday, October 11, 2020, the Inspector General of Police (IGP) Mohammed Adamu disbanded SARS following a widespread protest from Nigerians worldwide.
However, since the announcement that SARS has been scrapped, the protesters have refused to leave the streets, which Sagay says might force the Federal Government to take drastic measures against the protesting youths.
Sagay who alleged that the protest has been hijacked by hoodlums, added that having done what the youths requested, the Federal Government may have no choice than to forcefully put an end to the protests if the youths continue.
”I believe the youths should be satisfied at this stage. If the youths still come out tomorrow again, then it will look as if the whole demonstration has a hidden agenda for which EndSARS is being used as a cover. It will seem there is an agenda to disturb the stability of the country and engage in activities that may be along the line of #RevolutionNow which itself is the highest crime in our constitution.
“In such a situation, the government will have no choice than to bring an end to it and nobody will be able to complain then,” Sagay said.


The Mist and Endangered star Thomas Jane will star in The Veil, the latest micro-budget horror film from Jason Blum’s Blumhouse that has Phil Joanou on board to direct, THR reports.
“The story springs from the real-world headlines of religious cults and mass suicides. With Veil, it begins thirty years ago, when members of a religious cult known as Heaven’s Veil take their own lives. The truth behind what really happened remains buried deep in the memory of the sole survivor, a five-year-old girl, who returns to the compound with a documentary crew as an adult. They soon discover something that is far more terrifying than anything they could have imagined.“
Robert Ben Garant penned Veil, who is a co-creator of the comedy show “Reno 911!”, and also wrote Lionsgate’s Jessabelle.
Joanou is a video director who directed the Kim Basinger-Richard Gere erotic thriller Final Analysis but most recently teamed up with Jane to make the wildly popular short “The Punisher: Dirty Laundry,” an unauthorized take on the Marvel vigilante character.
The plan is to shoot this in April. Universal will distribute.
this week in horror
This Week in Horror - June 26, 2017 - The Evil Within 2, Jason...
The Evil Within 2 was shown at E3, Victor Miller is trying to get the rights back to Jason Voorhees, and Saw: Legacy has an official title! It's This Week in Horror with Whitney Moore!Posted by Bloody Disgusting on Monday, June 26, 2017
George A. Romero Has Passed Away at the Age of 77
Here’s the “American Horror Story” Season 7 Title Reveal! #SDCC
[Trailer] Guillermo del Toro’s ‘The Shape of Water’ Takes the Creature Out of the Lagoon
Here’s Why Bill Skarsgard Was Cast as Pennywise in ‘IT’
Freddy Krueger Appears in Epic ‘Ready Player One’ Trailer! #SDCC


text:
A major concern among patients with cancer is hair loss secondary to chemotherapy, an adverse effect that occurs among approximately 65% of patients who undergo this form of therapy.1 The association between chemotherapy and hair loss is well known across society, and chemotherapy-induced alopecia (CIA) can, therefore, induce a sense of violated privacy, or even shame, among those affected. The association of this adverse effect with reduced self-esteem, social confidence, and sexuality is particularly devastating for women. The anticipation of CIA is so distressing that some female patients even seriously consider refusing chemotherapy treatment.2
Identify all potential conflicts of interest that might be relevant to your comment.
Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.
Err on the side of full disclosure.
If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.
Not all submitted comments are published. Please see our commenting policy for details.
Basmanav FB, Nöthen MM, Betz RC. Insights Into the Biology of Persistent Chemotherapy-Induced Alopecia via Genomic Approaches—An Avenue to Clinical Translation? JAMA Dermatol. 2020;156(9):947–948. doi:10.1001/jamadermatol.2020.1866
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to:


text:
Gel-Forming Vaginal Tablet Helps To Control Spread Of AIDS
LONDON, 23 February 2012-In association with its client, Quay Pharma has developed a novel vaginal tablet which rapidly and completely forms a gel containing a potent microbiocide that blocks HIV from entering the bloodstream.
Of the 16,000 people around the world contracting HIV every day, the majority are infected by unprotected sex, with the greatest incidence being in sub-Saharan Africa and India. While work continues into the development of new drugs and vaccines, the use of microbiocides formulated as gels is currently considered the best chance yet of controlling the spread of AIDS; a recent finding suggested that a gel, applied inside the vagina, may reduce the chances of women contracting HIV by a third. A key benefit is that it offers an opportunity for women to protect themselves against infection where their partners are unwilling to use any form of protection.
Quay’s client, a large private non-profit corporation in the United States, has a long established research programme into methods of reducing the incidence of HIV sexual transmission. Following the screening of a large number of pharmaceutical acceptable compounds, the company found a compound that had good in-vitro activity against HIV and also had pronounced in-vivo efficacy against HIV challenge vaginally in animal models.
In order for the compound to be evaluated in clinical trials Quay’s client needed an effective means for its intra-vaginal administration. A variety of different methods were tried unsuccessfully, with particular problems being that many of the excipients used in the formation of creams and gels proved an irritant to the sensitive vaginal mucosae or did not provide entire mucosae coverage and therefore protection.
Quay was approached to develop a novel vaginal tablet that, once administered, would be able to gel very quickly to produce a clear, non-irritant, barrier layer that was undetectable by the male partner during intercourse. The requirement was for the tablet to rapidly and completely gel within less than two minutes in 2mls of simulated vaginal fluid and to develop mucoadherent properties within five minutes, and to ensure that the gel remained in the vagina during intercourse. Additionally, the gel formed from the tablet needed to have an acidic pH of 3 – 5 and remain acidic (pH<6) when mixed in-vitro with a volume of semen typical of a human ejaculate.
Using Quay’s expertise in tablet formulation development, many possible formulations were proposed and tried out experimentally, using various acceptable and non-irritant swellable polymers. Ensuring that a complete gel was formed quickly and completely was made even more difficult by the requirement that the gel had to be formed with only very small amounts of water present (2mls). The formulation finally selected and progressed was the one that could be compressed most easily into vaginal tablets.
Patent filings have now taken place for the selected tablet, which is planned to be assessed in extensive clinical trials.
"This has been a very exciting and challenging project and we are very proud to have made such a significant contribution," comments Mike Rubinstein, Quay Pharma’s Chief Executive.
"We believe this development will be a very significant milestone in the battle to protect people against HIV/AIDS infection and will be especially welcomed in developing countries as an inexpensive and culturally acceptable method of protection."
Bob Bushby/John Atkin
Nielsen McAllister PR Limited
Tel: 44 1332 293939
Fax: 44 1332 382202
Tel: 44 151 203 9800
Fax: 44 1244 281 283
Posted: February 2012

domain: biology


our concept & mission
Our goal is to provide our investors and consumers with quick, affordable, and highly advanced blockchain technology, which will completely transform the blockchain industry.
We aim to build an enduring technology finance firm open up the world to newfound. We are radically optimistic about crypto’s potential to restore trust and enable new kinds of governance.
We believe that crypto is just getting started. We have an optimistic view of the future and believe in crypto’s potential and the use of the blockchain as the main underlying technology.
We build and leverage technology to decode market dynamics. We continuously seek to harness novel technology systems and software across our firm—from risk management, trade execution, custody.
ICB NETWORK BIT in itself is a part of a wider, interconnected ecosystem aiming to deliver the best possible experience for everyone
icb network Platform
WHAT IS ICB NETWORK TECHNOLOGY
A groundbreaking Layer-1 blockchain project, the ICB Network uses the Proof of Stake (POS) consensus method to ensure consensus. With its innovative design, cutting-edge features, and unwavering dedication to efficiency, security, and scalability, the ICB Network is poised to shake up several sectors
We collaborate and are linked to leading companies in the sector.