Invetech says its Korus technology will offer industry an autologous cell therapy system that provides an option with minimal tech transfer challenges.
With the Korus system launched this week, Invetech is targeting autologous cell therapy developers, including those in the CAR-T, TIL, NK, DC therapeutics areas, who are looking to start their cell therapy manufacturing process with cleaner lymphocyte or monocyte populations – and improve their overall manufacturing yield.
The closed system includes elutriation and cell wash using gentle counterflow centrifugation and the firm claims it has supporting data demonstrating improved manufacturing performance compared to samples prepared by standard washing.
“Korus, like other elutriation-based devices, can save overall process cost by reducing the amount of off-target cells in starting material which can reduce expensive inputs like virus and selection agents,” an Invetech spokesperson told BioProcess Insider.
“Its wide processing volume range also allows autologous cell therapy makers to process an entire apheresis in one pass for elutriation, instead of having to use multiple units. It is also capable of performing downstream wash and concentrate processes down to 25ml.”
According to the firm, the Korus system can result in a 31% purer lymphocyte population, 49% improvement in T cell recovery after selection, 70% more T cells during expansion, and a 2.5x improvement in manufacturing yield.
It will also give industry an elutriation option that can handle relevant volume ranges from 25 ml to 5 L, we were told. “With the uncertainty around the availability of legacy elutriation systems in 2023, Korus provides an option with minimal tech transfer challenges.”


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As hexplained back here, the plan was to make 15 hexies a day for 133 days for a total of 2000 hexagons.
Well, I’m hexstatic to declare that it’s all going according to plan, hee hee. 27 days in, and I can proudly boast 405 little cuties in my collection. According to my calculations, that’s a respectable 20% done. Which is an actual real-life honest-to-goodness number. Am I’m doing it? Am I actually doing it?
I’ve even begun hand-sewing the lot together in little bunches of 16; I’ve got 9 of these bunches made up. It’s pretty neat seeing them all cozied up together as above.
Will my dream of a hexagon quilt actually happen? No one knows for sure I guess. But I’m now thinking that it really IS in the realm of possibilities.
Isn’t that hexciting?

domain: hobby


text:
It's not often that I see a website and just want to explore it, but that's what Robb Owen has achieved. I've literally gone back multiple times just to refresh my memory of it. There's something incredibly elegant in both the motion design and the colour palette. Plus, I'm a sucker for fast rendering cursor tracking animations 😅
I wish there wasn't an initial loading screen, but otherwise a truly enviable personal website.

domain: artistic


text:
|Catalog No.||2165||Similar Items|
|Brief Description||A Passover haggadah, written in a hiding place in France.||Similar Items|
|Registry No.||03255 R"M||Similar Items|
|Donor||Mussler Moshe||Similar Items|
|File name||Mossler Moshe - Hagadda||Similar Items|
|From Date||01/01/1942||Similar Items|
|To Date||31/12/1944||Similar Items|
|Author||Mussler Moshe||Similar Items|
|Date of event||1942||Similar Items|
|databank||Collections Section||Similar Items|
A Passover Haggadah. It was written from memory in a hiding - place in 1942 by Moshe Mussler, in the village of Lalanne in the district of Trie, France.
Moshe Mussler, born in Tarnobrzeg, Poland, lived with his wife and their two children in Belgium, where he worked as a teacher. During the period of the Second World War, the family was deported to several concentration camps in France. They were released from the Rivesaltes camp thanks to the intervention of Sarah, the wife of Yitzhak Bick of Antwerpen, who provided them with forged "Aryan" documents. The family settled in the village of Lalanne, where a French farmer employed Moshe as a laborer on his farm, knowing that he and his family were Jews.
In the Hebrew month of Adar 5702 (February 1942), Mussler began writing the Haggadah from memory. In its introduction he wrote: "...We are the sole Jewish family in this village. In the neighboring town of Trie there are six Jewish families, exiles and refugees from Belgium and occupied France, living in peace and quiet together with our French neighbors, who support us and feel for our fate."
The family survived and immigrated to Palestine.
Also in this collection:
- A letter sent by Moshe Mussler on October 5, 1942, to his brother in the USA, in which he asks his brother's assistance in helping the family immigrate there.
- Stories for children, written in Israel.
- His articles on his experiences in the Holocaust, which appeared in the press:
Ha - Tsofe (December 27, 1945); Ha - Olam, the central publication of the World Zionist Organization (February 7, 1946); Ha - Do'ar (undated); Dos Wort (February 2, 1945 and March 29, 1945); Davar (September 1, 1948); and Ha - Chayil, the daily newspaper for Palestinian Jewish soldiers (September 21, 1945 and December 7, 1945).
- His letter, dated 1951, to the Ghetto Fighters' House. Close

domain: library


By Carol Marbin Miller
A decade ago, amid perhaps the worst foster care debacle in state history,
Florida lawmakers transferred all foster care and adoption efforts to private management — hoping local leaders could nurture what the state long could not: a scandal-free child welfare system.
But even as the Department of Children & Families’ top administrator is on the defensive over a series of recent child deaths, Secretary David Wilkins has become mired in a second front by launching an unprecedented effort to increase control over the local child welfare providers that were supposed to remain mostly autonomous.
The battle is not going well.
The first two community-based care lead agencies that were asked to sign contracts giving Wilkins new powers over hiring and operation have both balked, inspiring accusations that the secretary is mounting a hostile takeover.
“When the Legislature created the CBC [community-based care] model, it was the intent to have local communities run the child welfare system, since the state of Florida had failed many at-risk children by neglecting the very services these children and families require,” state Sen. Aaron Bean wrote in a June 5 letter to Wilkins on behalf of the Jacksonville group, called Family Support Services of North Florida. “In essence,” he added, “children were being lost.”
“I sincerely hope you understand the importance of maintaining the integrity of what the Legislature intended when the local…model was enacted over ten years ago,” added Bean, a Jacksonville Republican. “Since that time, the local CBCs have made tremendous progress.”
Wilkins insists he’s simply trying to impose greater oversight and improve performance.
“I wanted more accountability in our nonprofit contracts,” Wilkins told The Miami Herald. “I did not think it is fair to tax and allocate money on nonprofits that are not accountable for the outcomes associated with the contracts.”
By 2005, all 67 of Florida’s counties had shifted to the private management of foster care, licensing and adoption services. Statewide, 19 lead agencies — including Our Kids, which covers Miami-Dade and Monroe counties — manage contracts with scores of subcontractors totaling roughly $750 million in state and federal money each year.
The road has not always been smooth. A handful of lead agencies — which carry out all child welfare efforts in their local areas except child abuse investigations and legal affairs — were fired following highly publicized scandals. But with a few exceptions, the local groups have enjoyed far greater success than did the state.
Wilkins believes the improvements are a result of his efforts at scoring and ranking the groups’ performance on a host of criteria, and then distributing the results broadly. Over time, he said, the poor-performing groups have gotten better.
“Performance has gone up dramatically,” Wilkins said. “Accountability and competition do drive performance.”
Wilkins is clearly irritated by the opposition to his proposals, which, he says, are designed only to standardize contracting among the lead agencies and to increase oversight.
Among the clauses that have angered the local groups:
• A provision that gives DCF veto power over the hiring of top CBC executives. Wilkins said this provision is intended to prevent the “bait and switch” that sometimes goes on when local groups identify one person as the top executive, but then introduce someone entirely different as the top officer after the contract is signed.
“When you change leadership, we ought to have a vote,” Wilkins said.
Another provision that allows DCF to impose new requirements and initiatives after the contracts are inked, without providing additional dollars. That clause, Wilkins said, is important because the secretary must have authority to develop new child welfare policies and implement them statewide. This year, for example, Wilkins is unveiling a new effort to dramatically bolster programs aimed at preventing child abuse.
Contrary to the CBCs’ claims, what the new contracts are not designed to do, Wilkins said, is re-centralize control over Florida’s child welfare system in Tallahassee.
“They’re saying we’re putting Tallahassee back in control,” Wilkins said. “Nothing in the contract takes away any authority or responsibility from the community.”
The programs in three Northeast Florida counties are at risk of expiring as lead agencies based in Jacksonville and Melbourne have yet to sign the new contract provisions. In Melbourne, the County Commission paid $1.2 million to create the Brevard Family Partnership, which the county still largely oversees.
“We have not been given the opportunity to negotiate any of the new terms and conditions of the revised standard contract,” Stockton Whitten, board chairman of Brevard Family Partnership and a deputy Brevard County manager, wrote in a May 24 letter.
Kurt Kelly, a former lawmaker who heads up the Florida Coalition for Children, an association of private child welfare providers, said his membership is eager to restore a sense of “collaboration” between DCF and the local groups it sired. But, he added, he expects the CBCs to remain unified in their opposition to the new contract language.
Kelly said he’s never heard of a child welfare nonprofit dangling a well-qualified chief executive at the state, only to substitute a lesser-qualified boss. “If Secretary Wilkins wants to come in and say he gets that choice, that’s a big problem for us,” Kelly said. “He’s building a policy on a straw man, and that just doesn’t work.”
Advocates of local control insist they already are accountable: to their boards of directors, which include civic and business leaders, doctors, lawyers and judges, to DCF, and to their communities, which had grown tired of endless foster care scandals.
Local ownership — not scorecards — has spawned the kind of innovation that propelled Florida’s foster care system into a national model, Kelly said. When lawmakers approved private management, the state was still reeling from some of the worst scandals in its history, including the disappearance and possible murder of then-5-year-old Rilya Wilson, whose state-approved Miami caregiver was convicted of kidnapping earlier this year, and still faces a retrial on murder charges.
“They had messed it up so bad the Legislature had to come in,” Kelly said. “We have gone from one of the worst to first, and we have a statute that protects what we do.”
“We don’t work for the secretary,” Kelly said. “We work with the secretary.”


text:
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In Country Ragamuffins, Maxine Bergerson Werner invites readers on a journey back to the 1950s as she recalls her upbringing as the oldest girl among eight siblings in a Norwegian farming community in rural Minnesota. To convey and preserve the experiences, values, and character of a typical Midwestern farm family of the time "before those memories... more...
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domain: literature


JUDr. Jan Vychyta, email: firstname.lastname@example.org
The article deals with a position of a public prosecutor in a trial stage of criminal proceeding as proposed in a draft of a new Czech Code of Criminal Procedure published in 2018. The author analyses the draft from a viewpoint of a public prosecutor, compares it to previously published governmental white papers as well as to foreign legislation and suggests certain adjustments. The author draws a conclusion that the draft of a new Code of Criminal Procedure does not strictly follow any of the white papers and the proposed changes to criminal procedure should be considered as an evolution of current legislation, rather than a revolution bound to replace historically prevalent procedural principles. However, chosen approach might be overall better suited due to general social apprehension of criminal justice as well as legal tradition.


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domain: game


FOX Exclusive: Former Iraqi Vice President Allawi speaks on US relations, Trump
By Benjamin Hall Published March 05, 2017 FoxNews.com
As President Trump begins to lay out his policies for the Middle East, he will find a region in chaos -- and impossible choices ahead.
But in an exclusive interview with Fox News, the former vice president of Iraq, Ayad Allawi, said he looks forward optimistically to the president's policies, as he looks back sadly at former President Barack Obama’s errors.
Speaking at his home in central Baghdad for the first time since Trump's election, Allawi is now able to open up about Obama's major mistakes, which critics say brought Iraq into turmoil and which Trump will need to address.
“America has lost a lot of potential friends here in the region. … and this is something that the new administration has to address.”
Obama’s principal error, says Allawi, was his disengagement from a country and a region which desperately needed U.S. support. At a time when Iraq couldn’t stand on its own, Obama left -- leaving a vacuum for Iran to fill. Iran’s new influence, he says, is behind much of the bloodshed.
“When our American friends left Iraq in 2011 they never laid down the issues that would strengthen the Iraqis to face the challenges ahead -- their sudden withdrawal in 2011 without the necessary preparation left us many problems to face.
Allawi, who also served as interim prime minister in 2014-2015, was very clear about Iran’s impact.
“It’s leading to bloodshed, to catastrophes and to wars around the Middle East….It has been a destabilizing factor. It’s destabilizing Iraq, it’s destabilizing Syria – it’s destabilizing other areas.”
This Iranian influence, he said, could be traced firmly back to Obama. In 2010, Allawi won the elections in Iraq, winning the seats, but was pressured by the Obama administration to back down -- in a direct interference with the political system.
“Biden came several times here; in fact, he used to come once a week to convince me to withdraw my interest and I told him we are not interested in withdrawing.”
Eventually Obama got his way, and Iranian-backed Nouri Maliki stepped in. This is the moment Allawi sees as a turning point for Iraq… Today large parts of the army are under Iranian control (via their support for Shia militias) and many state institutions also answer to Iran.
Today another country is also moving into the region – Russia. But Allawi believes Russian President Vladimir Putin can and should be worked with to defeat ISIS.
“I don’t think we should look at competition here between the U.S. and Russia, but rather as supplementing each other, and this is what I look forward to -- what the new administration will do.”
Allawi also doesn’t believe the battle against ISIS is the final one.
“I can see a lot of problems that will emerge after ISIS is defeated because I always say that not only is the military victory against ISIS enough, it needs to be supported by political gains."
Allawi says he hopes to unite Iraq -- Sunni, Shia and Kurdish -- but acknowledges it won’t be easy -- Iraq is engulfed in sectarianism -- and many in the region, not least Iran, thrive on division.
He also hoped for U.S. support moving forward.
“We don’t want to see more American power here, we don’t want to see more American troops here, we don’t want to see more Americans being killed here in this country. But we need the political leverage of the U.S. to help Iraq and to develop Iraq."


The East Antrim MLA stated: “I am glad that NIE has finally woken up to the need for price cuts. These cuts are long overdue and they move electricity prices into line with gas prices, which were reduced recently.
“In early February, I called on NIE to reduce their prices following the Phoenix gas announcement, and I am very pleased that they have taken this step
“I am also glad that the prices here are now on a par with the rest of the UK. This represents fairness.
“Its time that local consumers were given value for money and that local utility providers gave them a better deal. Its good to see that this process has started and I will work to ensure it continues.”


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Musician and filmmaker Chris Malinowski used Delaware as the backdrop for his band The Collingwood’s new music video, “Confetti.”
For nearly three decades, Mal’s Music sat on Kirkwood Highway, where a young Chris Malinowski grew up learning how to play guitar from this father, Mal, as well as the ins and outs of the industry.
Since Malinowski was little, he had a love for music. When he turned 11, he started his first rock band, Freakshow (1986–1991). In college, he played for a goth band, The Absurd (1992–1995). After film school in New York, and then a brief stint in Los Angeles, he created The Collingwood in 1999. The poetic rock band has released five albums, and recently created its latest music video, “Confetti,” in Delaware.
After college, he took a break from the music scene to focus on his filmmaking career and, after moving back home, he realized how much he missed it. Malinowski describes The Collingwood as an expressive outlet that also allows others in the state to connect with him over shared music tastes.
“I noticed that there was still some type of a music scene in Delaware and I longed to perform again,” he says. “But none of the bands were playing music I liked. … I became interested in ambient rock music, which is essentially heavy film score music for a film that doesn’t exist.
“I wanted to fill a void in the local music scene and in my heart,” he continues. “I got homesick for the stage and studio. I knew I still had musical chapters to write. Thus, The Collingwood came to fruition.”
After years of performing, the pandemic forced The Collingwood to take a pause. Malinowski focused his efforts on teaching private guitar lessons. This past year has brought with it a lot of change and pain for everyone, Malinowski says, noting his own deep sadness and longing for those in his life he’s lost, which inspired him to create music again. Soon after, he created his latest single.
“The lyrics were a plea to the deities and cycles of nature to show us some mercy,” he explains. “The proverbial emotional vessel needed to empty in order to welcome new, electric energies.”
As he was recording the soundtrack at DaSa Studios in Pike Creek, Malinowski realized that the track was missing a female voice. So, he incorporated Jules Corridori, a former guitar student and family friend from Cab Calloway High School to sing along with him.
“She sings like no one I’ve ever heard,” Malinowski says. “She is preternaturally gifted and she has a commanding presence. I brought her in to record, and her harmonies added a lush, eeriness to the piece.”
Malinowski is also a filmmaker by nature, and feels that every audio should have a visual. Music videos allow him to be more creative, without the constrains of time, crew members or gear.
“Confetti” was filmed at two of his friends’ beautiful historic homes in Newark, by White Clay Creek, and in Hockessin. His love of Delaware—his first home before settling in Maryland—and the picturesque scenes that his friends’ homes painted encouraged Malinowski to film the video in the area.
“Delaware was my first home,” he says. “[I]t exudes a natural pulchritude, not enough of which has been captured by a production. …My feature film, Yes, Your Tide is Cold and Dark, Sir was written as a love letter to Lewes, Delaware, and to my father. I’m obsessed with the quietude and history of that town, and I was lucky enough to film there and in Rehoboth.”
The Collingwood is currently working on completing their latest album and they have big plans for their future music videos.


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Rockefeller and Money: Not the Usual Problem
By FRANK LYNN ();
October 13, 1974,
, Section WR, Page 1, Column , words
To many, the accumulation of money is an end in itself. Nelson Aldrich Rockefeller achieved that end at birth. For him, money must have another end, whether it is personal comfort and convenience, charity or power.


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French Bulldogs are known for overeating. They will see appetizing everything that their owners put in front of them and also everything they find in their path. For that reason, control in the diet of these canines is vital since otherwise they will not only gain weight significantly but will also suffer from health problems.
Dogs don’t really need fruits in their diet, but that doesn’t mean you can give them some treats as they love them. Not all fruits are suitable for this breed of dog, so it is important that you know which ones you should avoid giving your French Bulldog and which ones can really be beneficial.
There are many fruits that provide many benefits for these dogs, but we will talk about oranges in this article.
Can My French Bulldog Really Eat Oranges?
Many people might think that oranges are toxic to dogs, but that is not the case. They are very delicious fruits that your French Bulldog will love.
However, you should make sure not to give this dog too many oranges as that could be detrimental to its health in the future. Similarly, you should only feed your dog the orange slices because the peels and seeds are dangerous as it could choke on them.
Oranges contain vitamin C, which is usually safe for your French Bulldog as it will be diluted within its body and then eliminated through its urine. In fact, if your pet has trouble producing vitamin C, this fruit is a great option to meet that need.
Can Oranges Be Negative for Our French Bulldog?
It depends! Although oranges are not toxic, they could be harmful to certain canines depending on their organism and also on the number of oranges you give them.
For example, diabetic or overweight French Bulldogs cannot consume the oranges’ high calorie and sugar content. Therefore, unfortunately, we cannot include this fruit in your diet. However, we can still feed them oranges as long as we control the amount.
Veterinarians always recommend the 90/10 rule, which means that we should only give our pets this type of food without exceeding 10% of their daily calorie intake. Therefore, it is recommended to use these fruits as treats only at specific times of the day, either after exercising, training, etc.
Also, you should be careful with orange seeds and peels. Both can be difficult for your French Bulldog to digest as they are difficult for its stomach to break down. Always feed your pet the orange slices.
Due to many toxic foods for dogs, many people think that oranges could be deadly for their pets. Oranges cannot kill French Bulldogs as they are not toxic or poisonous fruits. However, they could make the animal sick, especially if they consume it with its peel and seeds.
How Should We Prepare the Oranges for Our French Bulldog?
As we’ve said before, make sure you only give your canine orange slices. Do not let it eat the orange peels or seeds, as it will risk choking.
Sometimes your French Bulldog can get bored of eating oranges, so you could use some recipes to create certain treats with this fruit. Make sure that these recipes do not consist of orange cakes, ice creams, jellies or marmalades as they contain high levels of sugar that can affect your French Bulldog’s body.
Many people wonder if their French Bulldogs can drink orange juice. While this type of juice may have a citrus flavour, it is surprisingly delicious for French Bulldogs. However, if you are thinking of giving your dog orange juice, do not do it frequently as it is not usually as healthy for dogs as it is for humans.
How Many Times a Week Can I Give My French Bulldog Oranges?
As we have already said, veterinarians recommend that any fruit used as a treat should not represent more than 10% of your French Bulldog’s caloric intake. For that reason, it’s best to give your pet orange slices once or twice a week. That will not only satisfy its vitamin needs but also satisfy its craving for this delicious fruit.
Too many oranges could cause problems in obese and diabetic French Bulldogs due to their high sugar levels. Also, the extra calories can be harmful to any breed.

domain: pet


text:
Yesterday and today have become R&R days as I get myself organized for the run up to Charleston, SC this week, and on up to Norfolk, VA by mid May. Originally I had plans to be back on the water by today (Monday) but fairly strong winds, a great town to hang out in, and very cozy accommodations at Marsha and Ronnie‘s house, have kept me land-bound one more day.
While I was at the kayak store sorting out maps yesterday, a young couple stopped in looking for a seat cushion. They looked as though they’ve been on the water a while and someone asked where they were headed. It turns out that they started a couple weeks ago in St. Augustine, FL and are on their way as far north as they can get by Memorial Day. Like me, they’re taking advantage of a “between apartments” and “between Jobs/school” moment in their life to do their trip. Traveling with a 16 foot sit on top kayak and a 13 foot plastic sit inside they’re going a bit slower than me but, much like the turtle and the hare, they’re slow but steady progress allowed them to catch up with me here in Tybee. It was fun to swap notes on the route from Florida to here and interesting to see how many of the same places we ended up visiting. They’ve been utilizing marinas a fair amount to gain access to showers and a bit of civilization. After learning how well it has worked for them, I may be doing the same when the need arises.
Regan and Ashley taking boats to demo
Yesterday wasn’t spent completely off the water for me. A young man named Ashley stopped by the store to look at some kayaks and I accompanied him as he demoed a couple. It turns out that he has aspirations to paddle the length of the Missouri River (and possibly beyond). By hooking up with a place like Sea Kayak GA and folks like Ronnie and Marsha, I know he’s on the right track.
On a borrowed beach cruiser bike from Ronnie, I’m now on my way to explore the town. With luck I’ll find a post office and lunch along the way.

domain: geography


text:
Ham's F-12 Nutrient Mixture (F-12) has since been used for serum-free growth of CHO cultures as well as serum-supplemented growth of other mammalian cells, including chondrocytes and rat prostate epithelial cells. This Ham's F-12 is modified as follows: with L-glutamine, phenol red; without sodium bicarbonate.
- Contains zinc, putrescine, hypoxanthine, and thymidine
- Serum-free growth of CHO cells in F-12 has led to variety of improved formulations
- Contains no proteins or growth factors
- Requires supplementation, commonly with 10% Fetal Bovine Serum (FBS)
- Uses sodium bicarbonate buffer system (1.176g/L) and therefore requires 5-10% CO2 environment to maintain physiological pH
- Powder forms of Gibco cell culture medium require sodium bicarbonate supplementation, pH adjustment, and filtration at the time of preparation
Cell Culture, Mammalian Cell Culture
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Gibco F-12 is manufactured at a cGMP compliant facility located in Grand Island, New York. The facility is registered with the FDA as a medical device manufacturer and is certified to ISO 13485 standards.
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|Biotin, Calcium Chloride (CaCl2) (anhyd.), Choline chloride, Cupric sulfate (CuSO4-5H2O), D-Calcium pantothenate, D-Glucose (Dextrose), Ferric sulfate (FeSO4-7H2O), Folic Acid, Glycine, Hypoxanthine Na, L-Alanine, L-Arginine hydrochloride, L-Asparagine-H2O, L-Aspartic acid, L-Cysteine hydrochloride-H2O, L-Glutamic Acid, L-Glutamine, L-Histidine hydrochloride-H2O, L-Isoleucine, L-Leucine, L-Lysine hydrochloride, L-Methionine, L-Phenylalanine, L-Proline, L-Serine, L-Threonine, L-Tryptophan, L-Tyrosine disodium salt dihydrate, L-Valine, Linoleic Acid, Lipoic Acid, Magnesium Chloride (anhydrous), Niacinamide, Phenol Red, Potassium Chloride (KCl), Putrescine 2HCl, Pyridoxine hydrochloride, Riboflavin, Sodium Chloride (NaCl), Sodium Phosphate dibasic (Na2HPO4) anhydrous, Sodium Pyruvate, Thiamine hydrochloride, Thymidine, Vitamin B12, Zinc sulfate (ZnSO4-7H2O), i-Inositol|
|Storage: 2-8° C. Shelf life: 36 months from date of manufacture|

domain: chemistry


A firefighter and a dispatcher are accused of forcing a 12-year-old boy from Ludlow into sex slavery and prostitution until he was 25.
Brett Bartolotta, 42, of Cavendish, and Frank Meyer, 39, of West Haven, Conn., are accused of showering the victim with gifts when they'd visit Vermont to get him to participate in sex acts, including wrapping him in cellophane and hanging him from the ceiling. Police say they busted the men during a sting where the victim wore a wire.
Bartolotta is a veteran firefighter with the West Haven, Conn., fire department who owns a home in Cavendish. Meyer is a dispatcher with the West Haven Connecticut Police and Fire departments.
Bartolotta and Meyer were arrested Wednesday. They both pleaded innocent to the charges Thursday and were held on bail.
Friday, April 18 2014 10:13 PM EDT2014-04-19 02:13:23 GMT
A mother and her five-old child were taken to Fletcher Allen Friday night after being hit by a car in Winooski. Police say the accident happened around 8-30 at the intersection of West Spring and NorthMore >>
A mother and her five-old child were taken to Fletcher Allen Friday night after being hit by a car in Winooski.More >>
Friday, April 18 2014 5:16 PM EDT2014-04-18 21:16:40 GMT
Vt. State Police say a small plane has crashed on Interstate 89 north in Highgate. A state airport official confirms that a single-engine aerobatic plane was in the vicinity of the Franklin County StateMore >>
The pilot of a small plane parachuted to safety before his aircraft crashed on Interstate 89 north in Highgate Friday. More >>


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Step 5: Final Business Plan
The objective of this step is to develop a second draft of the business plan (including financial part). After a commitment from higher management to pursue full development of the proposal, an in-depth assessment of the initiative needs to be conducted, including the development of an investment plan (including the discussions with internal and external financers). For the completion of this step, several additional element need to be assessed and explored.
Firstly, the science and technology concept should be developed. The technology concept should make the connection between the (science & technology) innovation concept and the business. The technology concept should also showcase the added value of sharing expertise, infrastructure and joining activities.
Secondly, as the brokerage services offered by DIHs should be explored. Brokerage supports interaction at different levels, matches parties to technologies, and provides information to the network. As brokerage may be provided for financial services, it is important that the brokerage is organized prior to the development of the financial part of the business plan and the second assessment of the business services/models.
Thirdly, the organization and governance of the DIH should be outlined. This is has an important impact on financial issues, since it addresses participation, contributions from partners, cost of personnel, infrastructure, etc.
Fourthly, Based on the information collected in all of the preceding steps, the DIH needs to define a multi-annual financial plan, with an overview of revenues resulting from the services, and the costs . Based on the overview of costs and revenues, the potential financing gap for the DIH should be identified and a strategy to fill this gap should be formulated.
In order to close the financing gap, the DIH needs to assess different funding sources, including debt, equity, and public financing as well as in-kind contributions. Combining all these funding sources is a challenging task for DIH but the DIH needs to ensure that all its activities are sufficiently funded.
In order to assist SMEs in crossing the ‘valley of death’, DIH could also provide information and assistance to SMEs related to access to finance. There are different ways in which DIH could assist SMEs, including through brokerage in the form of business advice, matching activities to investors, and providing links to important national and European funding programs.
Finally, all these elements need to be discussed with the partners and investors and included in the second draft of the business plan.

domain: economics


Indian state-owned shipbuilder, Mazagon Dock Limited (MDL) has launched the Indian Navy’s fifth Modified Scorpene/Kalvari class diesel-electric attack submarine, the future INS Vagir, during a ceremony at its shipyard in Mumbai on Nov. 12, 2020.
The vessel was ceremoniously launched by Minister of State for Defence Shripad Naik through video conferencing. The ceremony was attended by Vice Admiral R B Pandit, the Chief of Staff of the Western Naval Command.
The submarine, Yard No. 11879, was towed to Mumbai Port Trust, for separation from the pontoon, after which she will undergo rigorous trials and tests, both in harbour and at sea before delivery to the Indian Navy.
Kalvari class is a class of diesel-electric hunter-killer submarines (SSK) being built for the Indian Navy. The submarines of the class are based on Scorpène-class submarines designed by French shipbuilder NAVAL Group (earlier DCNS) and are being manufactured at Mazagon Dock Limited in Mumbai under transfer of technology (ToT).
The submarines have a length of 67.5 m, height of 12.3 m, overall beam of 6.2 m and a draught of 5.8 m. The class displaces 1,615 tonnes when surfaced and 1,775 tonnes when submerged.
Each ship is powered by four MTU 12V 396 SE84 diesel engines, has 360 battery cells for power and has a silent Permanently Magnetised Propulsion Motor. The vessels can reach a top speed of 20 knots (37 km/h) when submerged and 11 knots when surfaced.
The submarines have a range of 6,500 nmi (12,000 km) at 8 kn (15 km/h) when surfaced and are capable of diving to 350 meters. Each submarine has a complement of 8 officers and 35 sailors.
The boats can be armed with indigenously-developed Varunastra heavyweight torpedoes, French MBDA SM39 Exocet submarine-launched anti-ship missiles (AShM) and naval mines. The Exocet SM39 is a sea-skimming, subsonic, solid-fueled anti-ship missile with an approximate operational range of 50-70 kilometres depending on the variant.
The class and submarines take their names from the first submarines inducted in the Indian Navy – first three after Kalvari-class and the next three after Vela-class (both variants of Soviet Foxtrot-class submarines).
The first submarine of the class, is INS Kalvari was commissioned into the Indian Navy fleet during a ceremony in Mumbai on Dec. 14, 2017 after a delay of almost four years. The second of the class, INS Khanderi, was commissioned into the fleet on Sept. 28, 2019.
The third submarine of the class, to be named INS Karanj, was launched in Jan. 31, 2018 and the fourth, the future INS Vela, was launched on May 6, 2019. Both will be delivered to the Navy after the completion of the sea trials.
According to the shipbuilder, the one remaining vessel of the class – to be named INS Vagsheer – is in advanced stages of construction and will be delivered to the Navy in 2022.


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Author(s): Simon Wroe
Following his expulsion from school, seventeen-year-old dreamer Ellis Dau is sent to work with his father. His father is editor of The Chronicle, the last bastion of free speech in their strange, strange land. And it is under threat: from heavy-handed policemen, mysterious revolutionaries, and the resident Russian billionaire.
As Ellis navigates his collapsing, blacked-out city - and his feelings for the oligarch's beautiful daughter - he realises that some things are worth fighting for. But can he save his family and the newspaper fuelled only by youth, grain spirit and unrequited love?
Holden Caulfield by way of Gary Shteyngart, Ellis Dau calls to mind the narrators of Skippy Dies, Submarine and Absurdistan, but has a charm and energy which is very much his own.
Shortlisted for Bollinger Everyman Wodehouse Prize 2017.
Simon Wroe is a freelance journalist and former chef. He writes food and culture features for The Guardian and arts reviews for The Economist. His first book, Chop Chop, was shortlisted for the 2014 Costa First Novel Award, longlisted for the Desmond Elliott Prize and won a Betty Trask Award. He was born in 1982 and lives in Camberwell, south London.


This week, instead of walking into a gun shop and handing over my credit card to buy firearms, bullets and grenades, I decided to try a different route: I downloaded highly detailed schematics — like blueprints for a house — of dozens of functional weapons and bullets.
If I had the time, a little technical know-how or was willing to sit through tutorials online, I could buy a three-dimensional printer (which makes objects by spraying thin layers of plastic that become shapes) and print and assemble some of these guns.
Among the files now sitting on my laptop are parts for an M16, AR-15, AK-47 and other semiautomatic guns. There are files for handguns, including a Glock, Beretta and a .22-caliber Ruger.
In late 2012, when I first wrote that 3-D printers could be used to make functional pistols, gun enthusiasts and government officials said the concept was science fiction and would take years to become a reality, if ever. Yet it took only a few months before videos popped up online of working guns made from 3-D printers, some capable of firing dozens of bullets.
Now the Internet is scattered with hundreds of videos of people shooting several different kinds of untraceable plastic guns.
The government is flummoxed about what to do. Last year the State Department tried to ban people from sharing files for one of these guns, called the Liberator. Yet here it is, sitting on my laptop. Along with hundreds of other 3-D files. The Department of Homeland Security anticipated this problem, sending a memo to law enforcement noting that “Limiting access may be impossible.”
Ginger Colburn, a spokeswoman for the Bureau of Alcohol, Tobacco and Firearms, said it is not illegal to print and make a gun in your own home. Yet if someone were to print an all-plastic gun, they would be breaking the Undetectable Firearms Act, which prohibits owning a gun that cannot be seen in a metal detector.
It took me about five minutes to find these gun schematics online. A teenager who grew up on the Internet could probably find them in half that time.
Not all of the plans I downloaded have been tested to ensure they work; some are concepts. But people I contacted in the underground proliferation of guns from 3-D printers, who all operate anonymously, said that almost all of the files are technically accurate, and most have been printed, tested and, in many cases, used to fire bullets.
One anonymous guide I found online called “3-D Printable Firearms” shows a list of working guns, how much they cost and how well they work.
There’s the Liberator plastic gun, which can shoot one bullet and costs $9.30 in plastic parts to print. The Liberator Pepperbox has been upgraded to shoot four bullets and costs a little more. And one of the more popular designs, called the Reprringer, can shoot a single .22 cartridge and costs only $2.41 to print. (You will need to spend a dollar or two more on some screws and a spring.)
Gun lobbyists argue that 3-D printed guns are pointless because many of these weapons can be fired only a few times before the gun breaks, often overheating and cracking. But last I checked, one shot is enough to kill someone. (The Reprringer is based on the design of the derringer pistol, which killed President Lincoln.)
“Weapons experts will tell you these guns are a joke and not that serious,” said Hod Lipson, director of the Cornell University Creative Machines Lab. “But that’s exactly the problem. Plastic guns are easy to fabricate, they can be used just a few times and you can make guns that don’t look like guns.”
What’s more, he noted, these weapons are very difficult to detect at security points, as they often don’t have metal parts or, if they do, just a spring and a couple of screws, all of which could easily pass through a metal detector.
Mr. Lipson, who is an author of the book “Fabricated: The New World of 3D Printing,” said the public should worry not so much about these weapons falling into the hands of terrorists or hardened criminals, who already have access to most any weapon they desire. “The real danger is kids and teenagers and hobbyists who will attempt to make these,” he said.
Indeed, holiday gift guides this year will be filled with tech-related gadgetry, including lots of 3-D printers that now cost as little as $250.
Last month Home Depot began selling the higher-end MakerBot, a 3-D printer that costs $1,375. Asked if the company worries that teenagers could use these store-bought printers to make a gun, Home Depot declined to comment, passing me along to MakerBot, which said it has banned sharing any 3-D gun files on its website. MakerBot has not, however, banned people from printing gun files.
But it seems that the 3-D printing companies are the only ones in this equation that could offer some protection against the proliferation of 3-D printed guns, especially when it comes to children who may try to make them. These companies could ensure that 3-D printers can’t print certain parts, or can only access approved websites to download files.
But instead, most 3-D printing companies I reached out to did not respond to a request for comment. MakerBot simply referred me to their “terms of service” disclaimer, which prohibits sharing weapons files on their website.
For gun enthusiasts, this is all good news.
When I visited one of the main meeting points online for 3-D guns, the Free Open Source Software and Computer Aided Design, or Fosscad, which hosts anonymous forums, files and resources for people interested in 3-D printed guns, members of the site were hard at work building and testing more files for more guns.
In the site’s private chat section, some with whom I spoke didn’t worry about teenagers being able to make guns, noting that it still requires mechanical expertise.
“The printing alone is NOT easy,” said a member who goes by the name WarFairy. “It isn’t just click and print like you can do with a garden gnome.”
As anyone who has needed a 12-year-old to fix their iPhone or reprogram the TV knows, technical expertise isn’t much of a hurdle for today’s teenagers.
Fosscad members said that assembling a single-shot 3-D gun can take about five hours. “The biggest thing I’m looking forward to is making existing things easier to print,” WarFairy said.
For now, Fosscad members have grander goals than decreasing the time it takes to make a gun. They are collaborating to build and test a semiautomatic gun to be made of 90 percent plastic parts from a 3-D printer. They are far along in the design phase and when they succeed, the members told me proudly, those files will be freely shared online.


Anchor Rashmi Gautam has always been an active buzz maker with her glamorous content. On the sets of Jabardast and on the silver screen in films like Guntur Talkies, she never shies away from pouring out her hotness whether or the others like it.
Now named of the hottest Telugu Anchors on TV, the actress celebrated her birthday on Saturday with her family and friends, also shared the joy with her fans by sharing her celebration pictures from her party. Speaking of her transformation as she passed every year, the actress says she is way more matured person now.
She no longer bothers about the petty things like pimples and clear skin like many women in the industry do. Also grown as a person who is able to take more of negativity and stay absolutely unaffected by them.
She is right, experience gives it all. We wish her many more happy birthdays to come and cherish.


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The Cauldron Spirits and Brews seeks to entice your senses and taste buds. The intimate setting features a dark and cozy atmosphere with eclectic antiques and overstuffed chairs. A rug softens the cold, stone floor before the lounge fireplace and eponymous house cauldron. Large wooden beams protrude from the ceiling. Ornately-framed vintage illustrations of witches and black cats hang from the haunted walls.
The menu includes familiar bites with a wicked twist and French inspiration. Home-cooked comfort food complements a selection of specialty drinks and themed beverages that encourage sharing and sampling.

domain: design


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Trials of a new testicular cancer drug, called TE 23, have been halted in Britain after a 27-year-old patient died of overdose. But elsewhere in the country, trials continue.
Gary Foster, 27, was repeatedly given twice the amount of chemotherapy drugs he should have been prescribed. He was due to be married this month.
Reports have said his death was caused by an error in the setting up of the trial on the computer system at University College London Hospital (UCLH).
When the Medical Research Council (MRC) suspected patients had been given overdoses, instead of calling the hospital immediately it wrote a letter - which a nurse at UCLH failed to open until two days after Foster had died.
Foster's mother Colleen said: "Gary was slowly poisoned to death.
"We just thought Gary was getting tired because of the chemotherapy."
The incident raises fresh questions about the safety of medical testing in Britain, Daily Telegraph reports.
Two years ago six men almost died in the so-called "elephant man" case at Northwick Park Hospital, North London.
Their bodies swelled horrifically after they were given the experimental drug TGN1412.
UCLH has been forced to suspend the trial, called TE23, which tests whether a combination of five drugs is better at treating testicular cancer than the standard treatment of three drugs.
But the trials continue in other UK hospitals.
Foster, a graphic designer, had just been diagnosed with testicular cancer.
He was told he had a 60 per cent chance of survival.
The disease has a 95 per cent survival rate when caught early.
Foster was told about the TE23 trial and told that if he was accepted on to it, his chances of survival would increase.
His fiancée, Paula Collins, 35, told The Sunday Times: "When Gary became involved in the trial, we thought it was fantastic news because we thought Gary's chance of survival would be greater and the care would be better.
"The trial sister said: 'Good news, Gary, you have been selected for the trial.' At UCLH they said, 'Don't worry, testicular cancer is curable. We will monitor Gary for 10 years - you don't have to worry.' They made us feel so confident."
Foster received the drugs during visits to UCLH between June and September 2007. On seven occasions, he received 30,000 units of bleomycin - of one of the five drugs - instead of 15,000.
A third patient died at a different hospital after receiving an overdose of the same drug due to an error by a nurse or doctor. However the MRC, the government body which ran the trial, said the drug was not the direct cause of his death.
An inquest heard Mr Foster began to show signs of deterioration after taking the drugs.
Eventually he developed a dry cough, a symptom of damage to his lungs that had been caused by the overdose of bleomycin. The lung damage was eventually fatal.
The inquest heard the cough should have been recognised by doctors and nurses as a warning sign. However, he was given a final dose.
Miss Collins said: "We had dreams and lots of plans together. Gary also had his own ambitions. We were supposed to be getting married. He was such a lovely person. He was so well liked and had so many friends."
"We do need trials but there need to be more controls," Collins added.
"I would encourage other people thinking about taking part in trials to proceed with caution. I would hate to think of anyone else going through what we have gone through."
"Checks should have been carried out. It is incomprehensible that they were dealing with the most dangerous medicines and they were so blasé. It was so slapdash."
Mrs Foster said: "An overdose gives the impression that it was a one-off. It was seven times.
"Every week my poor Gary was going into hospital, we thought he was getting better but, actually, he was being slowly poisoned and poisoned to death."
In a statement, UCLH said: "We would like to reiterate our deepest sympathy and condolences to the family and friends of Mr Foster."
It said it has introduced measures to make medical tests safer.
The MRC said it had reviewed its trial procedures as a result of Mr Foster's death and subsequently introduced additional checks.

domain: medical


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Sure, there’s Facebook and Farmville on the Internet, but how many useful websites do you have on your favorites bar?
Here are just a few useful websites that will get your favorites bar in better condition.
The beginning of the 21st century has often been hailed as the Age of Information, but it begs the question of just whose information it is the age of.
With the increasing prevalence of social networking Web sites, a large amount of previously private information is now being made accessible and shared on the Internet.
“The first thing we want everyone to understand about the Internet is that it’s all public domain,” said Brophy Dean Mr. Jim Bopp about the Internet at large.
The expansion of the Internet’s user base and sharing capability has brought with it many benefits, but also many concerns.
One of the biggest we’ve seen is that of privacy.
This concern has been exacerbated by the large expansion in the use of social networking sites like Facebook.
“I use Facebook every day,” typed Greg Ali ’12 and Christopher Frame ’12 in an interview conducted on the social networking site.
“It allows for communication in a way I’ve never experienced before,” Ali added.
According to the Web site “All Facebook,” Facebook users, now in the 400 millions, share five times more than they did six months ago, bringing the average status amount to 12 per week.
Are you lacking in social networking sites?
Myspace was two years ago, and maybe you’re bored with your Facebook page.
Did you ever wonder if your pets would like something like Facebook? Dogster.com is the answer to your doggone problems.
With most newspapers now online and even more newspapers closing their doors, it is a time of change within the journalism community.
In light of these changes, here at The Roundup we have made some changes of our own.
This year we have put a greater focus on technology and have made several significant advancements in our online distribution.
According to a recent story in The Week, there were two girls in South Australia that found themselves stuck in a storm drain.
However, realizing they had their cell phones, the girls used their quick thinking and good judgment and decided on the best course of action: updating their Facebook statuses.

domain: news


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Thank you to everyone who participated in our 3 days of Sister Stamps Blog Candy Giveaways. Here are the winners:
Mei-Li Blog Candy Winner - haumeaola said
Congrats to Sister Stamps. Mei-Li just lights up my inspiration to make more cards. Luv it all!
Mei-Li Blog Candy Winner - hilogurl87 said
So cute this stamp. I just love the whole collection. I was so excited to pick up my stamp yesterday but something came up! :-( now i have to wait till tuesday so i can make it over to pick it up...
Kiyomi Blog Candy Winner - Creations by Shirl said
Gorgeous card - I can't wait to pickup up stamps today, Yeh!...
Please contact Michele at the store by calling 933-9390 or emailing her at firstname.lastname@example.org to claim your prize by July 20, 2011.


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17 people have
NISHTA is a 2 Day Boot Camp workshop curated especially using techniques of Indian Traditional Art forms, Kalaripayattu, and Yoga for an Individual's holistic development.
Whether you are a dancer, a fitness enthusiast, a homemaker, a working professional, or any Individual who wishes to learn, experience, and include the Indian traditional fitness sessions in your day-to-day regime, all are welcome.
This is a unique opportunity to meet and learn from the Masters of Kerala, and learn the science behind these unique art forms.
Please call +91 8089143192 for more details about the workshop.
Note: This workshop is suitable for all age groups above 16+years old
What To Expect:
- All the materials needed for the workshop will be provided by the host
- F&B is not included
About The Creators & Host:
This Workshop is brought to you by DAES., Instagram handle @daes_expressjon. They are an Art and Culture space, based in Cochin, Kerala where regular traditional Kalaripayattu and Yoga, Art and Dance sessions are being taught for the last several years.
The workshop would be hosted by two Master Instructors in Kalaripayattu and Yoga


Controlling and preventing the growth of microorganisms in a cooling tower is extremely important and required to keep the system running at optimal levels. The presence of microorganisms will cause the system to breakdown and decreases the efficiency of the heat transfer. Typically oxidizing biocides such as chlorine and bromine have been used to treat cooling water. Unfortunately these chemicals are highly reactive with other chemicals and microbiological species found in the water. Chlorine dioxide however...
By Applied Oxidation LLC based in Chattanooga, TENNESSEE (USA).
Monitoring Biomass in (Cooling Tower) Waters through ATP monitoring
The TOXcontrol can be used for ATP monitoring. Currently our company is doing research for further developments for this application on the TOXcontrol.
Monitoring the microbial population of cooling towers is necessary in order to maintain the proper operation of the system. Conventional methods for monitoring microbial populations work by culturing microorganisms, a time-consuming procedure that requires days or...
By microLAN B.V. - Aqualabo Group based in Waalwijk, NETHERLANDS.
Chlorine dioxide is a significant product in the control of algae, planktonic and sessile bacteria, bio-film and scale in power plants, cooling towers, loops and cooling systems. CleanOxide helps maintain the efficiency of heat exchanger surfaces, reservoir intakes and ancillary equipment. Traditional oxidising agents such as chlorine and bromine, on the other hand, are associated with pH constraints and corrosion problems.
By NW Solutions based in Perth, AUSTRALIA.
Need help finding the right suppliers? Try XPRT Sourcing. Let the XPRTs do the work for you


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Something was terribly wrong at this restaurant when six of us went for dinner there on Sunday night. The atmosphere was very cozy and welcoming, but the staff was anything but! The head waiter actually was rolling his eyes and sighing when we were asking questions about the menu. At that point we should have walked out! Waiters were literally running around but totally ignoring us! When the food came they threw it in front of us and ran away! I was given the wrong entree I tried to tell him, but he was already out if sight! The food was good but the experience was the only negative one we had on our 10 day vacation in Europe! We sat with dirty dishes for 5 minutes and was never even asked if we wanted coffee or dessert! We are still scratching our heads wondering why a restaurant would treat customers in such a way! Perhaps, Americans are not welcome here!
If you own or manage Restaurant La Cucina, register now for free tools to enhance your listing, attract new reviews, and respond to reviewers.

domain: travel


Trenchless Technologies to Install Lower Conner Creek Interceptor
December 29, 2022Read Article
Rock Bore Using HDD, Open Cut, and Carrier Pipe Construction...
The cities of Willow Park & Hudson Oaks also wanted to maintain a PVC pipe system to match their existing water system p...
August 7, 2023


Although the coronavirus has already seen urban environments improve drastically this year, when life returns to normal the benefits will once again diminish. If local authorities want to improve urban environments in 2020, they therefore need to address the most pressing challenges.
Here, we’ll look at the current challenges facing urban environments and what local authorities could do to improve them.
What challenges affect urban environments?
The main challenges presented in urban environments include:
- Air pollution
In the UK, there are said to be between 28,000 to 36,000 deaths related to long term air pollution exposure. The majority of these are in urban environments. Largely caused by vehicle emissions and industrial plants, air pollution is having a major impact on both our health and the environment.
Technology is another challenge that needs to be addressed. It progresses at such a significant speed, and it is crucial to keeping cities connected and competitive. Environmental technologies are particularly needed such as that which can help to cool buildings and harness solar power.
Finally, resources are another potential challenge. Listed as one of the main challenges urban environments face right now, it includes energy, food and water. Urban environments result in increased demand for energy, while water catchment areas are reduced by urban sprawl. The reduction in green spaces also negatively impacts liveability.
These are just some of the main challenges presented in urban environments today.
How can local authorities address these challenges?
While there are a lot of challenges in urban environments, there are things local authorities can do to address and overcome them.
Air pollution can be addressed by working alongside firms such as ERG. They offer the latest technological solutions to help lower air pollution levels. The adoption of all-electric vehicles is also something they will be doing once they hit the mainstream. This will drastically reduce carbon emissions in urban environments.
To make cities more liveable, the introduction of more greenery is also required. This could include creating mini parks, or just planting additional trees and shrubs in urban environments. Not only does this make them look more attractive, but it also cleans the air.
Investment into the latest technologies is also crucial. This includes updating infrastructures so they can cope with the newest updates. The introduction of 5G will also help to boost the economy and provide faster technological solutions in urban environments. Particular focus should also be placed on investing in environmental technologies.
In terms of resources, investing in renewable energy sources will help to address the ever-increasing demand for services. Fertile land also needs to be protected, ensuring food can continue to be grown even as the population grows.
Overall, there are a lot of challenges faced in urban environments. The above are just some of them and the steps that could be taken to address them. It isn’t going to be easy, but unless action is taken, urban environments could find themselves in real trouble over the next decade.
You may also like: 5 Ways Your Business Can Help Save The Environment


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"Insights on Valuation"
The latest issue of our “Insights on Valuation” newsletter is now available. Arxis Financial, Inc. is pleased to provide this highly respected, nationwide publication which features valuable information that is applicable to many litigation matters. Topics in this issue include:
• Standards of Value — Legal Definition: When we discuss “Standards of Value,” we usually will do so in the context of the purpose of a valuation engagement. There are other times when we need to recognize that the Standard of Value may be defined directly by law, specific contracts, legal documents, or indirectly as interpreted by case law.
• Value Impact of Key Employee: Often the value of a company is diminished by the loss of a key employee, either to competition, disability, or death. A key employee is someone who has been intimately involved with the operations of the company in a position working closely with customers. The employee has certain skills, maintains key contacts, or possesses other attributes that cannot be easily replaced. The valuation issue is the business’ vulnerability to the loss of such a key employee and how that loss might be mitigated.
• Business Valuation: In business valuation, risk is the variability of returns from an investment. This means uncertainty as to both the amount of cash flows as well as the timing of their receipt. The best measure of this uncertainty ...
Simply click on the link above to access the newsletter. We hope that you find it to be informative. If for any reason you wish to unsubscribe, please let us know.

domain: finance


Arab News, FII Institute partner to shed light on the future of regional media industry
Cooperation to produce research, panel discussions and industry level, government white papers
Riyadh: Arab News — the Middle East’s leading English language daily — is partnering with the Future Investment Initiative Institute to shed light on the future of the regional media industry.
The year-long cooperation — marking the newspaper’s 46th anniversary — will see the co-production of a series of expert panel discussions, surveys, white papers and recommendations of how the industry can survive the digital disruption and create sustainable models for the future.
“The past two decades saw traditional media dramatically impacted by rapidly developing technology. The rise of tech giants, social media platforms has created an uneven competitive environment and curtailed many traditional media outlets ability to have a sustainable growth model, be it through advertising or subscription models,” said Faisal J. Abbas, Editor-in-Chief of Arab News.
“While technology has had a positive impact on many new businesses and individual content creators/influencers; it has meant that established, credible media organizations are left with no means to sustain the costly process of producing, editing and disseminating credible news. It has also made it easier for other entities to illegally benefit from, infringe on these organizations copy rights.” He added.
The partnership between Arab News and FII Institute will see the larger impact of technology on economic models of media businesses discussed. It will also cover topics such as the negative impact of social media platforms on matters such as the rise of fake news, increase in hate speech and loss of personal privacy.
“As part of the FII institute commitment to empowering the world’s brightest ideas to materialize and scale sustainability, we are delighted to partner with Arab News on this deep dive into the media industry, and find solutions to help the industry evolve and resolve its digital transformation issues,” said Richard Attias, CEO of the FII Institute.
“As such, we invite all key players — be it traditional media, tech companies, social media platforms, advertising agencies, government officials — to take part in the discussions as per the year-long agenda which will be announced soon. By including the relevant stake holders, we are sure our Institute and Arab News can help bringing points of view closer, identify exact issues and hopefully come up with creative solutions to all of them,” added FII Institute’s Richard Attias.
The first deliverable of this cooperation, will be a white paper produced by the Arab News Research and Studies Unit (RSU) based in London. The paper, to be released in May, will be published under the title of “The Myth of Digital Transformation” and will seek to explain in detail the technical problems that face the media industry from a commercial perspective and what impact do they have on various levels.
The paper will be available for distribution via Arab News and the FII Institute websites, and a panel discussion will be held following its release to shed light on its findings.
About Arab News
Established in 1975, the Riyadh-based Arab News is the Middle East’s leading English language daily. Part of regional publishing powerhouse, SRMG, Arab News has been Saudi Arabia’s newspaper of record for over four decades, it has regional hubs in London, Dubai, Islamabad and Tokyo. Since 2016, the newspaper has undergone a digital transformation strategy which saw it enhance its web presence and launch three additional digital editions: Arab News Pakistan, Arab News Japan, and Arab News en Francais.
For more details, visit: www.arabnews.com
About the Future Investment Initiative Institute (FII-Institute)
The Future Investment Initiative Institute is a new generation of non-for-profit global foundation that seeks to empower the world’s brightest ideas to materialize and scale sustainably. The FII-Institute will act as the curator of the global conversation on humanity’s most pressing societal issues, sparking concrete actions and mobilizing cross-border thought leadership, collaboration and resources to cater for an accelerated impact in the short- and mid-term, while also creating long-term platforms that have the potential to significantly shape the future of our societies.
Click on link for more information on FII-Institute
Follow FII-Institute on LinkedIn and Twitter (@FIIKSA) to keep up with the latest news
Media Contact: email@example.com
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Video: Vaughn Gittin Jr. Shows “Ultimate Funhaver” Ford F-150
Truck Built for Hooning on Dirt and Track
When you think of drift cars, typically high-powered domestics, LS-swapped Nissan 240 SXs, and late ’90s Toyota Supras come to mind. Put those same cars on a dirt course and their street-and-track–oriented underpinnings show their limitations. Race driver Vaughn Gittin Jr. wanted a hoonable vehicle for both the track and the dirt and started with the new 2015 Ford F-150 as the basis. Dubbed the “Ultimate Funhaver,” the truck combines off-the-shelf and custom parts for having a blast on dirt or track.
Built by Kibbetech in Southern California, the truck has an unusually low-to-the-ground stance for driving around the track, but it is ready to play in the dirt in seconds thanks to a custom AirLift airbag suspension. Shocks are King dual bypass front and triple-bypass shocks in the rear. While hooning around solo is fun, it’s more fun with some friends along. To facilitate group hoonage, the Funhaver features five Recaro race seats with Takata harnesses. To make the big truck flingable, an ASD hand brake helps kick out the rearend on-demand. Tires are 35-inch Nitto Terra Grappler G2s on 18-inch RTR wheels.
The engine is mostly stock 3.5L EcoBoost V-6, with a K&N intake, Magnaflow custom exhaust, and Revolution Automotive custom tune. Power hits the pavement through a Currie full-floating rear axle. You can check out all the hoontastic fun in the video below.
Source: Ford Racing via DrivingLine
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text:
The Navalny Challenge Behind the Scenes of Russia's Imitated Democracy
Part 2: Allowing the People to Speak
Zhirinovsky has a spacious corner office in parliament. Signs hanging on the walls point to an obsession with hygiene. "Please no hugs, handshakes or kisses."
When asked what exactly he is engaged in, opposition politics or theater acting, he says: "Of course we behave tactically ahead of votes. But we stand opposed to the government and to the president. We're a little bit like the flu. Do you want us to turn into tuberculosis?" The opposition as a contagious disease -- it's an interesting metaphor.
In June, a serious mishap occured on the stage of the Russian political theater -- one which provides an insight into the role played by the Duma. Moscow Mayor Sergei Sobyanin had developed a plan to tear down all of the five-story residential buildings erected from the 1950s to the 1970s and rehouse 1.5 million Muscovites in modern residential towers. The 47-billion-euro project was conceived as a gift to the electorate -- and to the construction lobby. The parliament was to quickly pass a law giving the mayor a free hand for resettlement and construction. But things turned out differently when furious apartment owners began protesting the attempt to expropriate them.
Nobody inside Russia's patriarchic bureaucracy had apparently foreseen such a reaction. In response, Duma Chairman Volodin invited a handpicked group of those affected by the plan to a "parliamentary hearing." Some of those opposed to the planned demolitions were also allowed to have their say and the mayor politely responded to them. The leaders of the protests, though, weren't allowed in, left instead to demonstrate outside.
The hearing was broadcast live on television and was the liveliest event that had taken place in the Duma for quite some time. It was like a successful theater production: It presented the Duma as a place where those in power listened to common citizens. Yet the opposite was true: If representatives of the people must be replaced by the people themselves before those in power are willing to listen, then something has gone badly wrong in a representational democracy.
The renovation law bore all the hallmarks of the construction lobby, which has joined forces with municipal housing companies to create one of the most powerful interest groups in Russian politics, says political scientist Yekaterina Schulman. "They don't care about elections. They don't think about Putin. They crush everybody who gets in their way."
Other interest groups -- retail, agriculture, defense or competing secret service agencies -- have their own representatives in parliament. For them, the Duma is more than just decoration. "It is reminiscent of the lobbyism practiced in democracies," Schulman says, "with one important distinction: Among the interests represented by parliamentarians, those of the voters themselves are missing." Everyone has a lobby -- except for the citizens of Russia.
Waking Up from a Slumber
The Duma is therefore best imagined as a stock exchange, a place where Russia's bureaucratic class negotiates how to apply the instructions coming from the Kremlin, who should be allowed to profit and to what degree. Only a tiny portion of these negotiations is visible on the plenary floor. The amount of leeway is entirely dependent on who stands behind a particular draft bill. It takes courage to stand up to the government, but it takes even more courage to stand up to the secret services. And opposing the president is unthinkable.
But if the Duma is more than just decoration and does represent a kind of stock exchange, then there exists within the system of imitated democracy the embryo of real politics, of an open conflict of interests worthy of the name. That, in any case, is what Schulman believes. The fact that this version of the Duma has an ambitious chairman in the form of Vyacheslav Volodin reinforces this trajectory, she says. "I wouldn't rule out him having aspirations for the presidency."
It would be good for the country if the Duma were to wake up from its slumber and finally fulfill its constitutional role. This would give Russia a place where political conflict is visible.
But if nothing happens, then the fight for power will continue to be carried out elsewhere -- either hidden behind the walls of the Kremlin, or amid the potential chaos of street protests and clashes between protesters and police. The chances for renewed protests have risen with Navalny's exclusion from the presidential election; the opposition politician has already called for a "voters' strike" and nationwide protests on Jan. 28 in response.
"A vote without competition is no vote at all," Navalny has said. Indeed, it looks as though Russians will have to tolerate their imitated democracy for a bit longer.
- Part 1: Behind the Scenes of Russia's Imitated Democracy
- Part 2: Allowing the People to Speak


text:
- Call number
- MssCol 2483
- Physical description
- .21 linear feet (1 volume)
- Preferred Citation
- An account of the late Negro insurrection which took place in the island of Barbados on Easter Sunday, Manuscripts and Archives Division, The New York Public Library
- Manuscripts and Archives Division
- Access to materials
- Advance notice required. Request access to this collection.
"An account of the late Negro insurrection which took place in the island of Barbados on Easter Sunday, April 14, 1816" comprises material from private letters and Barbados newspapers giving accounts of losses with names of owners of estates and Sir James Leith's proclamation denying that an order had been sent to the islands for the freeing of the slaves. Includes one color drawing. Bound together with John Poyer's 1808 publication, "The history of Barbados, from the first discovery of the island, in the year 1605, till the accession of Lord Seaforth, 1801."
Using the collection
LocationManuscripts and Archives Division
Stephen A. Schwarzman Building
Fifth Avenue at 42nd Street, New York, NY 10018-2788
Brooke Russell Astor Reading Room, Third Floor, Room 328
Access to materialsAdvance notice required. Request access to this collection.
Alternative form available
Available on microfilm; New York Public Library; *ZL-411


text:
Traditional panettone bread is a pretty involved project, so a recipe for easy panettone always makes me raise an eyebrow. I can’t help but be picky… I’m Italian! So I was excited to find a quick panettone recipe that requires very little work.
If you’re unfamiliar, panettone is a soft, sweet, and fragrant Italian yeast bread that’s studded with dried or candied fruit. It’s a holiday tradition in homes all over the world (like this tender, lemony shortbread recipe) because it’s a lot tastier than dense American or European fruitcakes. Since it’s enriched with both beaten eggs and melted butter, panettone has a rich softness that makes it so, so good. Think brioche, but more tender and with a special holiday feel. Plus, panettone bread is WAY less sweet bread than dense holiday fruitcake. YES!
Easy panettone bread… what’s the big deal?
If it’s so good, why doesn’t every single baker out there churn out panettone bread for Christmas every year? Well, a proper panettone can take up to two days to make, including mixing rising, etc. It also uses a sourdough starter or native yeast mixture, which can take weeks to develop at room temperature.
Or, you can buy panettone if you don’t want to deal with the hassle of making one. You can get mass-made panettone loaves for between $15-$30 from supermarkets and import stores, but they often have preservatives in them. Freshly-baked is the way to go, but a really good panettone bread costs up to $50 from artisan bakers. Zoinx!
Enter a quick and easy panettone recipe
I was very curious about this quick panettone bread method. It was developed by Zoë François and Jeff Hertzberg in their book Holiday and Celebration Bread in Five Minutes a Day. It requires only 15 minutes of actual work, plus a few passive hours for rising, chilling, and baking.
Basically it goes like this: you throw a bunch of stuff in a bowl, stir, let it sit out for two hours, then throw it in the fridge. Then you shape, let rise for 90 minutes, and throw in the oven. The actual work it very minimal. In fact, the only hands-on parts here are the stirring and shaping.
The result of this is not a traditional panettone recipe, but rather something closer to a quick-brioche. Regardless, this is a wonderful stand-in that everyday home bakers can make, even with minimal skills. My stoic, not easily impressed grandma REALLY liked this panettone bread. She doesn’t like much, so that’s a pretty solid endorsement.
Panettone bread equipment
You don’t really need any special equipment for this easy bread recipe. You can easily mix it with your hands or a wooden spoon. The only things you DO need are paper panettone molds, which you can get online pretty easily. (Sur la Table also sells paper molds in their local shops.) For this recipe you want a paper mold that is between 5.25- and 6-inches wide at the base. This is a pretty standard size.
Hanging quick panettone bread upside-down
When making traditional panettone, the method includes hanging the loves upside down after as soon as they come out of the oven. Here’s a great example of what it looks like to hang panettone. What you do is poke two thin bamboo skewers through the paper mold, slide them through the bread, and poke them out the other side. For this quick and easy recipe you don’t need to hang your bread, but it helps to keep them from sinking a bit as they cool.
If you want to hang panettone at home, it’s not very hard. I simply used whatever kebab skewers I had in my drawer, because pretty much any will work. Then I pushed two straight-back chairs back to back and hung the panettone bread between them. There they stayed until completely cool.
Here’s what it looked like:
So, there you go! This is an incredibly simple baking recipe and pretty much any home baker will be able to pull it off. Enjoy!
From the book:
Panettone bread is one of the most popular Christmas breads sold all over Italy (and the United States) during the holidays. It originated in Milan around the fifteenth century and has been the subject of much lore. A commonly told story of how this bejeweled bread came to be goes something like this. A young nobleman falls in love with a baker’s daughter named Toni. He disguises himself as a pastry chef ’s apprentice and creates the tall, fruit-studded bread to present to Toni, calling it “Pan de Toni.” The bread is a success in the bakery, and the father blesses the marriage.
The story is as rich and fanciful as the bread, made with dried fruit and the essence of lemons and vanilla. There are traditional panettone molds that are very high-sided and come either straight or fluted. They can be found at cooking stores or on the Web. You can use a brioche mold, but the bread won’t have the classic high sides. Paper panettone molds are available from baking supply stores.
Easy Panettone Bread
Makes three loaves that are about 1 1/2 pounds each. The recipe can easily be doubled or halved. From Holiday and Celebration Bread in 5 Minutes A Day by Zoê François and Jeff Hertzberg (©2018 St Martin's Press).
- 1 1/2 cups (12 ounces/340 grams) lukewarm water (100°F or below)
- 1 tablespoon (0.35 ounces/10 grams) granulated yeast see note #1
- 1 tablespoon (0.6 ounces/17 grams) Kosher salt
- 1/2 cup (6 ounces/170 grams) honey
- 8 whole (1 pound/455 grams) eggs
- 1 cup (8 ounces/225 grams) unsalted butter melted and slightly cooled
- 1 teaspoon lemon extract
- 2 teaspoons pure vanilla extract
- 2 teaspoons grated lemon zest
- 2 cups (12 ounces/340 grams) mixed dried and/or candied fruit see note #2
- 7 1/2 cups (2 pounds, 5 1/2 ounces/1,065 grams) all-purpose flour
- Egg wash 1 egg beaten + 1 tablespoon water, for brushing
- Pearl sugar for sprinkling
- Mixing and storing the dough: Mix the water, yeast, salt, honey, eggs, melted butter, extracts, and lemon zest in a 6-quart bowl or a lidded (not airtight) food container.
- Mix in the dried fruit and flour without kneading, using a heavy-duty stand mixer (with paddle), a Danish dough whisk, or a spoon. If you’re not using a machine, you may need to use wet hands to incorporate the last bit of flour. The dough will be loose, but will firm up when chilled (don’t try to use it without chilling).
- Cover (not airtight) and allow to rest at room temperature until the dough rises for 2 hours.
- The dough can be used as soon as it’s chilled after the initial rise, or frozen for later use. Refrigerate the container and use over the next 5 days. To freeze dough see note #3.
- On baking day, dust the surface of the refrigerated dough with flour and cut off a 1 1/2-pound (small cantaloupe-size) piece. Dust the piece with more flour and quickly shape it into a ball by stretching the surface of the dough around to the bottom. Rotate the ball a quarter-turn as you go. Place the ball in the paper panettone mold, seam side down.
- Cover loosely with plastic wrap and allow to rest at room temperature for 90 minutes.
- Preheat the oven to 350°F (176°C), with a rack placed in the center of the oven.
- Brush the panettone with egg wash. Bake for 50 to 55 minutes, or until golden brown and hollow-sounding when tapped. The amount of dough and baking times will vary depending on the panettone mold size.
- Allow to cool on a rack before serving.
- This easy panettone bread was made with active dry yeast — Red Star brand, though any brand of active dry yeast will work.
- Golden raisins, dried pineapple, dried apricots, dried cherries, candied orange peel, or candied lemon peel are a few fruits that we’ve tried and loved in this panettone bread.
- You can freeze thedough after its initial rise is completed. It's best to freeze dough in loaf-sized portions, then wrap tightly and freeze in a sealed container. Defrost in the fridge, then shape and bake as usual.

domain: food


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The essential amino acid that greatly aids the maintenance of proper protein balance in the body is threonine. This amino acid is very important for the development of the elastin, tooth enamel, and collagen. Threonine greatly assists liver and lipotropic function when mixed with aspartic acid and methionine. This essential amino acid strengthens the immune system by helping in the production of the antibodies. It may help in healing few types of depression as well.
The Following Is The List Of Foods Rich In Threonine:
Eggs are rich source of this essential amino acid. Proteins in eggs are made up of amino acids. And eggs contain all the nine essential amino acids. Because of the pattern of the essential amino acids in the protein of the eggs is similar to the pattern required by the human body, eggs are widely suggested as part of the balanced and healthy diet.
2. Pumpkin Seeds:
Pumpkin seeds are the good source of threonine, an essential amino acid required to create other essential amino acids such as serine and glycine. Poor levels of threonine in the body can lead to liver failure. Besides threonine, pumpkin seeds also contain plant based omega 3 fats, natural phytoestrogens, and alpha linolenic acid etc. Therefore, whenever you are on the mood for the chewy snack, prefer pumpkin seeds.
Another amazing dietary source of threonine is spinach. Besides this essential amino acid, spinach also consists of numerous minerals and vitamins. It is also concentrated in health promoting phytonutrients like carotenoids, Lutein, beta-carotene, Flavonoids and zeaxanthin. With all these nutrients spinach provides excellent anti-oxidant protection to the body.
In addition to beta-carotene, Vitamin C, Vitamin K and calcium this wonderful vegetable also consists of all the nine essential amino acids. In fact, this amazing vegetable is rich in threonine. Also, kale contains two compounds such as sulforaphane and indole 3 carbinol which are believed to have cancerogenic potentials. However, sulforaphane is destroyed by cooking. Mincing or steaming preserves the entire content.
Meat is another good source of threonine. In fact, the meat products play the major role in the human nutrition due to the presence of fat, protein, minerals, vitamins and essential amino acids along with other nutrients. Because of all these nutrients, nutritional scientists urge people to consume meat for both mental and physical health.
Mushroom protein contains all the nine essential amino acids including threonine which are required by man. Due to the presence of all the nine essential amino acids mushrooms are highly recommended to include as part of the diet for vegetarians.
Threonine is found in almonds as well. Consume few almonds on regular basis for keeping poor levels of threonine levels at bay. Actually, poor levels of threonine are found in those people with clinical depression. By consuming almonds regularly, you can keep the threonine deficiency at bay.
Beef is another dietary source of threonine. Moderate consumption of beef is suggested so as to keep the deficiency of threonine at bay. The deficiency of this essential amino acid can result in weakness and skin disorders. This amino acid is also very important for the antibody production to the body.
Fish is also loaded with threonine. Therefore, regular consumption of fish is very helpful in enhancing the threonine levels in the body. By increasing the levels of this amino acid, fish works wonders in reducing the risk of liver failure. Similarly, fish plays the pivotal role in reducing the risk of various diseases as well.