Anger spreads over guber polls
The protesters, who wore their dresses on the wrong side to connote abnormality, alleged that the election was won by Action Congress (AC) candidate, Dr. Kayode Fayemi, insisting that he was robbed of victory.
The development is coming as fresh break-out of violence in Osun and Kwara States led to the death of two persons including a soldier and destruction of property, among them eight vehicles.
This is as youths and the campaign organisation of AC’s governorship candidate in Edo, Adams Oshiomhole, issued the Independent National Electoral Commission (INEC) a 48-hour ultimatum to declare the "authentic result" of the Saturday election n the state or face mass protest.
In Osun, the police declared 23 AC members wanted, even as uneasy calm prevailed in Ondo State, following the orgy of violence and arson that rocked the state since Sunday in the aftermath of the elections.
Similar trends were reported in Taraba and Katsina, where three persons were killed and 12 public and private buildings destroyed.
The Adamawa State police, however, confirmed the arrest of 17 persons for various electoral offences, with 24 nabbed in Imo.
The Ekiti women, led by a two-time former Commissioner in the old Ondo and Ekiti states, Ronke Okunsanya, insisted that the people’s mandate was upturned by INEC and the powers-that-be and that Dr Fayemi should either be given his certificate as the deserved winner or the result of the election nullified.
Most of the women with green leaves in hand were shedding tears as they marched through some major roads in the state capital. "We're representing all the women in Ekiti State. We have the fact that Dr Kayode Fayemi won the election. We want the election cancelled in Ekiti State," Okunsanya said.
In another development, Ayo Akinyemi, the Chief Press Secretary to the state Administrator, Brig. Gen. Adetunji Olurin (retd) denied insinuations that Olurin had hand in the alleged rigging.
Akinyemi wondered why Ekiti people wanted to soil the name of the Administrator who put up his best to ensure that peace returned to the troubled state.
He told Daily Sun: "If this is how they want to thank the Administrator for the good work he had been doing in Ekiti State since the past six months, so be it. But posterity shall judge Ekiti in future.
The Administrator, everybody knows, is an experienced man who had led in peace. If any party is aggrieved, they know what to do. They should go to the Election Tribunal and sort themselves out instead of damaging the image of the Administrator."
Violence leading to the damage of about eight vehicles broke out in Idi-Ape area of Ilorin. Though no life was lost, five persons were arrested for the disturbance.
Daily Sun learnt that the youths of Idi-Ape were contesting the result of the just concluded election, with the complaint that in Idi-Ape, they voted massively for Democratic Peoples Party (DPP), but PDP was declared winner in the area. The Police Public Relations Officers Gideon Markus (DSP) who confirmed the incident said that the situation had been brought under control.
Edo Youth for True Democracy and members of the Special Duties Committee of Oshiomhole Campaign Organization issued the 48-hour ultimatum Tuesday at a press conference in Benin.
Chief Eruaga Sylvanus – Peters who spoke for the two groups said Edo people in exercising their democratic rights registered to vote and on election day chose to vote overwhelmingly for Comrade Adams Oshiomhole.
"We shall run out of patience after 48hours and shall be ready to die from their guns. By Thursday they will have many of us to kill", Chief Eruaga said, adding that the youths of Edo State shall all be in the streets to face the consequences of what comes out.
With the death of two more persons including a soldier, police in Osun state have declared 23 chiftains of the wanted. Among those wanted by the police are the party’s chairman, Alhaji Moshood Adeoti, the secretary, Prince Gboyega Famodun and a leader of the party, Senator Bayo Salami.
However, in a swift reaction, the AC governorship candidate, Rauf Aregbesola condemned the police action querrying what the offence of his men were other than offering to participate in the democratic exercise.
He said the attempt was to "behead" the party in the state so that those declared wanted would not be able to prepare and partake in the Saturday exercise.
The PDP in Osun State also raised alarm on alleged plans by the AC to disrupt the next presidential and national assembly election appealing to the police to protect the voters.
Addressing the press in Osogbo, chairman of the party's campaign committee in the state Chief Ebenezer Babatope lamented that despite the fore information given to the area commander four hours before the Ilesa mayhem started, nothing was done to save the situation.
Meanwhile, tension continue to heighten in Ondo State on Tuesday following the violence that erupted in some part of the state before and after the declaration of Governor Olusegun Agagu as the winner in the Saturday election.
Already many PDP leaders in the state are now seeking refuge at Government House for fear of molestation and attack by the irate protesters.


Ignore Fake News Claiming PTF Spent N22 Billion Fighting Covid-19 – APC Tells Nigerians
The attention of APC Mandate Defenders has been drawn to the fake news in some media outlets claiming that the Presidental Taskforce on Covid-19 (PTF), spent N22 billion in fighting Coronavirus between April 1st and July 31st this year.
Denying the report in a statement released to newsmen in Abuja on Monday, the National Publicity Secretary of the group, Mr. Ifeanyi Emeka noted that the report is not only false but was concocted to incite the Nigerian people against the good works the PTF is doing to flatten the Covid-19 curve in the country.
The group said that every dime spent and other activities undertaken by the PTF is documented and is already in the public domain for all Nigerians to see as part of the PTF’s transparency drive.
This can be noticed in the recent launch of Nigeria Resource Mobilisation Tracker Dashboard and the Nigeria Incidence and Response Tracker Dashboard by the Chairman of the PTF, Mr. Boss Mustapha. To get more information about the PTF, it’s expenditure and activities, click the following link https://statehouse.gov.ng/covid19/
The group further explained that every dime spent by the PTF was gotten through requisition letter and was never responsible for receiving monies from donors as the report suggested.
For the sake of emphasis, the PTF is a multi-sectoral body that coordinates and oversees inter-governmental efforts for the containment of the spread of Covid-19 in the country and not a money receiving body as the fake news alleged.
Accordingly, there are categories of donors as well as groups receiving and managing Covid-19 funds in the country.
We have the United Nations Covid-19 Basket Fund which serve as Covid-19 financing and investment forum for diverse stakeholders which manages donations from the United Nations, multilateral and bilateral organisations. This body have their own independent board known as ‘Project Management Board’ which approves every of its dime and activities.
The other group is the NNPC and it’s partners which mobilises oil companies to support the fight against Covid-19. Their fund is indenpendently managed and the PTF is never a party to that.
We also have the Private Sector Coalition Against Covid-19 which mobilises funds from public spirited individuals and establishments in the country. Their fund is also managed independently and the PTF is not involved in their internal affairs.
So, we wonder why any body or group would allege that the PTF spent N22 billion out of the phantom N31 billion it received from the Office of the Accountant-General of the Federation?
We are still asking to know what these fellows planting fake news against the PTF stands to benefit from their shambolic and disgraceful acts?
Must we always display our penchant for mischiefs at every given moment?
While we urge Nigerians to ignore the fake report, we call on them to continue to stay safe as well as take individual and collective responsibilities in the ongoing fight to flatten the Covid-19 curve.


Marin Citizens for Effective Transportation
² P.O. Box 6036 ² San Rafael, Ca 94903
Comparison between SMART Alternatives and Marin Citizens for Effective Transportation (MCET) Alternatives: Key Differences:
SMART District Board Members/Ms. Lillian Hames September 15, 2003
520 Mendocino Ave.
Santa Rosa, CA 95401
Dear Board Members and Ms. Hames:
Thank you for the opportunity to comment on the “Alternatives Description” provided to us by email. Our detailed comments are below. To fully understand our comments requires a review of the attached matrices (see Matrix 1, Matrix 2, and a comparison below) which we developed by following the examples on the FTA website. We recommend you use the matrix format to communicate what your final alternatives are.
As all of you are aware, before a major public investment in commuter rail is undertaken, SMART needs to provide information on whether such an investment can be justified on an economic basis. This is, in part, achieved by analyzing the proposed rail costs and benefits, broadly defined. This is an element of the analysis required by the FTA to obtain “New Starts” funding and we agree with the requirement.
A critical component of analyzing the costs and benefits of a proposed major public investment in commuter rail, and one that is also required by the FTA, is an alternatives analysis. In turn, a critical component of preparing an alternatives analysis is to specify and define the alternatives to the proposed investment in commuter rail, which SMART has done in draft form.
Unfortunately, based on our analysis of the detailed assumptions provided, SMART has made several errors which we believe will distort the analysis required by the FTA and mislead the public on the costs and benefits of the rail versus express bus alternatives. These errors are as follows:
1. SMART has incorrectly specified the Transportation System Management (TSM) alternative. As indicated in Attachment A, we believe a minimum of four TSM alternatives are required to fully understand and account for the costs and benefits of the train vs. express bus alternatives. A review of our proposed TSM alternatives shows that none of our proposed alternatives matches SMART’s proposed single TSM alternative because we believe SMART’s TSM alternative is unrealistic and poorly defined.
2. In its specifications of what it labels as the “Express-Bus-Alternative,” SMART proposes to include the capital costs of completing the HOV lanes in the Novato Narrows and elsewhere in Sonoma County, but does not include these costs in the rail alternatives.
· We believe it is misleading to include the HOV lane capital costs in any of the major investment alternatives. The completion of the HOV lanes through the Novato Narrows and elsewhere in Sonoma County and, therefore, the associated capital costs are not dependent on either the train or express bus alternatives occurring.
· The HOV lanes will encourage transit usage during peak hours and will enhance capacity and safety during off-peak hours. Environmental studies for HOV lanes through the Novato Narrows have been started; partial funding started, and the system is part of the RTP. It will be built. It is only matter of when.
· The existence of completed HOV lanes will impact the cost and ridership analyses. Just as completed HOV lanes will enhance express bus usage, they will also create competition for commuter rail service. We address this issue by varying this assumption in different TSM alternatives. In Attachment A, the incomplete HOV lanes are assumed TSM alternatives #1.2 and #1.3. Completed HOV lanes are assumed in TSM alternatives #2.2 and #2.3.
3. In the SMART draft, there would be no analysis of the impact of completed HOV lanes on rail ridership. This is an oversight and should be corrected.
We capture this by including the HOV lane completion in the two of the TSM alternatives, which means the rail investment alternatives be analyzed assuming completion of the HOV lanes in our alternatives #1.4 - #1.7.
4. SMART fails to specify a significant increase in express bus service in the corridor in any of its alternatives. There is no difference in bus routes and frequencies between its TSM and Express Bus alternatives. Furthermore, the TSM alternative does not specify a sufficiently large increase in express bus routes and frequencies in order for it to be considered to be comparable to the level of service provided by the rail alternative to Larkspur.
· We believe SMART needs to redefine its Express Bus alternative so that it actually represents a major investment alternative. This requires a significant increase in express routes that serve San Francisco bound commuters as well as employment centers in Marin south of San Rafael.
Ø SMART limits southbound express bus routes when it proposes that they travel no farther south than the Larkspur (or San Quentin) ferry terminal. Since providing trips by rail to one of these terminals implies providing trips for San Francisco bound commuters, SMART needs to specify an expansion of express bus services for these commuters.
Ø The official notice in the Federal Register acknowledges that Highway 101 is the primary mode connecting Sonoma and Marin Counties with San Francisco. SMART recognized the importance of the San Francisco connection by adding an extension to SMART rail to a SF bound ferry. The Regional Transportation Plan also describes connections to SF.
Ø In order to get a fair and impartial comparison between the express bus and rail alternatives, it is necessary to include this important leg of the trip all the way into SF. SMART needs to study the complete system. An express bus system in the North Bay would be a logical extension to existing bus service from Sonoma County, through Marin and into San Francisco. Nowhere has SMART specified a significant expansion in bus routes and frequencies into San Francisco and communities south of San Rafael. It needs to.
5. How much additional bus service should be included in the Express Bus alternative? We believe that the following two criteria should be used to design routes and frequencies:
(1) Express and intercounty bus ridership should approximately match the projected ridership of the rail alternatives
(2) Routes and frequencies should be chosen to maximize transportation user benefits per dollar invested.
Ø By specifying bus routes and frequencies using this guidance, the public will gain a better understanding of the how much the commuter rail vs. express buses cost. By specifying bus routes and frequencies using this guidance the public will be informed as to whether it is less costly to invest in express buses or commuter rail.
6. SMART assumes the ferry services will double in its TSM alternative. While we believe it prudent to assume some increase in ferry service is appropriate in two of the TSM alternatives, there may be different levels of ferry service that are needed to support rail passengers. This additional service level is not relevant to the MCET proposed Express Bus alternative.
7. SMART’s TSM alternative assumes too high a level of public transit infrastructure. This is more than would be conceivable even if a local sales tax increase obtained voter approval.
8. The alternatives analysis needs to be more honest in its Alternatives Analysis about the local political situation and the likelihood that SMART’s proposal will receive local public support.
· The City of Larkspur has stated on multiple occasions that SMART’s proposal for a ferry terminal is not consistent with Larkspur’s General Plan. Simultaneously, there is significant opposition in the state to closing San Quentin. As a result, SMART may have no acceptable location for a terminal south of San Rafael.
9. SMART’s draft incorrectly defines the rail to San Quentin alternative. There are significant changes in the supporting infrastructure and, therefore the capital costs, associated with moving a ferry terminal from Larkspur to San Quentin. This infrastructure needs to be specified and its costs included in the alternative.
We would be happy to meet with the SMART Board, its staff, or its consultants to discuss these issues at your convenience.
Michael R. Arnold, Ph.D. Joy Dahlgren, Ph.D.
Co-chair MCET Co-chair MCET
c. Congresswoman Lynn Woolsey
Marin County Board of Supervisors
Novato City Council
Mark Prado, Marin Independent Journal
Kerry Benefield, Santa Rosa Press Democrat
Peter Fimrite, San Francisco Chronicle
Leslie Rogers, Regional Administrator, FTA, Region IX
Matrix 1 - HOV lanes between Novato and Petaluma and Elsewhere in Sonoma County are Constructed in 12 Years
* Since in the two TSM alternatives the assumed ferry and bus services vary, rail and Express bus alternatives may need to be evaluated against each alternative separately to determine the extent to which they impact the evaluation. In addition, major investments with higher build TSM potentially means voter approval of two sales tax increases: one to support local infrastructure and one for the major investments.
Matrix 2 HOV Lanes are not Completed During the Planning Horizon
Notes: Since rail ridership is higher and bus ridership is low with HOV lanes not completed, alternative 2.8 is likely to have more bus routes and frequencies to match the rail ridership. Also, see notes on TSMs for Matrix 1.
There is what might be called a “blind faith”
that transit is the antidote to urban traffic congestion. In reality, however,
this view is largely false and leads to unrealistic expectations of transit.
Breach of Faith:


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Sterling Sapphire Filigree Teardrop Earrings - Created Blue Sapphire - CP185H6N8H7
Created Blue Sapphire
Payment security - Secure Transactions Using Paypal
Quick Ship - Leaves Warehouse in 1-2 Business Days
Return policy - 30 Days Free Exchange & Return Policy
- These beautiful dangle earrings feature 6x4mm oval created blue sapphire gemstones set in a teardrop shaped filigree design.
- The earrings are crafted of 925 sterling silver and are nickel & tarnish free. They are secured by fishhook backs.
- This Jewelry Piece is an Awesome Gift for Birthdays, Anniversaries, Wedding Party, Holiday, Graduation etc.
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domain: artistic


The QuickShelf Safe from QuickSafes is a hidden compartment shelf that uses RFID technology. Unlike typical magnet locks, RFID locks are uniquely "keyed" and cannot be hacked for unauthorized entry. The QuickShelf is a beautiful piece of furniture and is ideal for firearm concealment while providing secure and immediate access to its contents. It is made of real Birch veneer laminated wood for added strength. It has a natural wood colored finish.
The hinges are spring loaded and adjustable to any desired angle from 30 to 90 deg. The lock system has an illuminating LED, indicating RFID sensing, low battery , dis-allowed RFID card, and other modes. The safe includes 4 pre-programmed RFID keys (two credit card RFID keys, one FOB, one 3/4" round token) and can be programmed for up to 16 unique RFID keys. The kit includes mounting hardware, a back-up battery pack, and 4 AA batteries. It mounts easily on most wall surfaces.


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Babaeko To Speak At Advertising Week Conference Tomorrow
By Tunji Faleye
Suave advertising guru and Chief Executive Officer / Chief Creative Officer of X3M Ideas Group, Steve Babaeko will be speaking on influencer marketing at this year’s Advertising Week’s (AW2020) immersive virtual conference on Wednesday September 30, 2020.
The AW2020 starts from September 29 till October 9, 2020.
Advertising Week is a worldwide gathering of marketing, advertising, technology and brand professionals. From daytime seminars and workshops featuring some of the industry’s brightest minds to organized networking and world-class entertainment, Advertising Week which is a one-of-a-kind experience crosses the globe with events in New York, London, Tokyo, Mexico City, Sydney and Johannesburg.
The inclusion of Babaeko, the president of the Association of Advertising Agencies of Nigeria (AAAN) to bring his exposure and experience to bear when talking about influencer marketing does not come as a surprise, as he was also named among Adweek’s 100 Most Fascinating People in Marketing, Media and Culture for 2019. This is in line with Adweek’s practice of celebrating the Creative 100, a roster of gifted professionals who inspire current and future generations not only with their work but also their passion for creativity across advertising, media, art, literature, animation and more.
Babaeko is renowned for his creativity and consistency as he has successfully taken one of Nigeria’s most innovative creative agencies, X3M Ideas to greater height, establishing X3M Ideas SA PTY to serve the business interest of the agency in the Southern African region.
The X3M boss began his career in 1995 with MC&A Saatchi & Saatchi where he worked for five years, then to Prima Garnet Ogilvy, where he also worked for another five years. He also spent 7 years at 141 Worldwide, where he worked as creative director before establishing X3M Ideas in 2012.
He has served on the Grand Jury of the New York Advertising Festival, as well as being a keynote speaker at the 2018 International Advertising Association conference. His impressive stint in the International advertising scene also saw him act as judge on the 2017 The Loerie Awards.


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The Courtyard by Marriott Hebbal is pulling out all the stops, with not one, but two delicious food festivals – one sweet and one savoury! The Hebbal Cafe is playing host to the pasta spread, while Glazed is pulling off a glorious selection of waffles and pancakes.
Choose from an extensive variety of flavours ranging from subtle to wholesome and rich. Savour some of the best home – made, fresh and flavourful pastas, signature sauces and all time Italian favourites like cannelloni, tortellini and mezzelune at The Hebbal Café – the all day dinner at Courtyard by Marriott Bengaluru Hebbal.
The menu features a selection of pastas infused with hand-picked ingredients like ricotta, asparagus, capers and much more. Don’t miss out on the delicious Cheese cream tortellini with grilled artichokes and asparagus stew, Mezzelune of olives and capers with smoked salmon and zucchini, burrata and rocket leaves. You won’t want to miss this one!
Satiate your sweet tooth and be spoilt for choice with a specially curated and wide range of offerings at Glazed. The menu features a selection of waffles and pancakes such as the all-time favourite’s Belgian chocolate waffles, American blueberry waffles, Scottish pancakes, Okonomiyaki pancakes, and much more. Both food festivals end on July 15th so hurry to get your fill!
Date: Till July 15th 2018
Venue: The Hebbal Cafe and Glazed, Courtyard by Marriott Hebbal
For Reservations: Call – (080) 6122 6777, 6122 6742

domain: food


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What a joke and insult to museums.
Tired, faded, not maintained, do not waste your time here.
5 minutes and was back out again, place should be shut down.
Once inside its another 5baht for toilrt through the massive steel turnstyle, some poor man was trapped in toilet and nobody around to help.
In fact the only good bit of our trip to remember the sacrafice made by so many was the War Cemetry.
Own or manage this property? Claim your listing for free to respond to reviews, update your profile and much more.

domain: travel


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Kilkenny Rose, Helena Hughes
The Kilkenny Rose pub quiz will take place in Brogan's Bar on John Street this Thursday.
Rose of Kilkenny, Helena Hughes is organising the event to help cover the cost of her trip to the Dome in Tralee next month, where she will represent the Marble City.
The quiz will start at 8pm and teams of four are €20. A raffle will also take place in aid of the Amber Women's Refuge.
Subscribe or register today to discover more from DonegalLive.ie
Buy the e-paper of the Donegal Democrat, Donegal People's Press, Donegal Post and Inish Times here for instant access to Donegal's premier news titles.
Keep up with the latest news from Donegal with our daily newsletter featuring the most important stories of the day delivered to your inbox every evening at 5pm.

domain: news


text:
The demon onslaughts of Doom and Painkiller have made the jump to Maksim Chudaev’s arena based battler Goinund. There are certainly a lot of targets to take down, but this is one title that lacks the finesse and polish that made its inspiration so great.
Sekiro: Shadows Die Twice Game Free Download
Saturday April 13, 2019
Sekiro: Shadows Die Twice Free Download PC Game Cracked in Direct Link and Torrent. Sekiro: Shadows Die Twice – Carve your own clever path to vengeance in an all-new adventure from developer FromSoftware, creators of Bloodborne and the Dark Souls series. About This Game With over 50 awards and nominations, Sekiro: Shadows Die Twice is […]
Players are thrown right into the thick of it in Goinund. With the ability to shoot white energy blasts, the entirety of the game takes place on a stone platform located high above the ground. Demons will magically appear out of nowhere, and each and every last one of them wants to take you down. However, ammo is infinite, and shooting down baddies can help players level up, granting them new abilities.
It’s a basic setup, and can be absolutely mindless at times. If anything, the key to victory is to wait in a corner, dodge fire, and blast at everything that comes your way. Abilities like a teleportation move and shotgun blast with cooldown can be unlocked, but none seem to work as well as the default blaster. Waiting in the corner is by far the best move players can make as well – movement is slippery and has the main character flying through the air, chunks of the stage disappear, and the borders of each world do not have barriers, making it easy to fly out. The area was not planned out, lacking any semblance of design or care.
ISLANDERS Game Free Download
Thursday April 18, 2019
ISLANDERS Free Download Full Version PC Game Cracked in Direct Link and Torrent. ISLANDERS is a strategy video game. About This Game A quick note from the developers: You want to build beautiful cities without investing hours on end into stressful resource management? Say no more! ISLANDERS should be right up your alley. ISLANDERS is […]
If anything, there is no major goal to the game other than to survive. It is fairly easy to unlock everything, with the final upgrade available after just a few minutes of play. There is a kill count at the bottom of the screen, and the game does get progressively harder, but almost everybody will see what this title has to offer in less than 10 minutes. Sure, one baddie may come at you with two blades instead of one, but the creator did not think hard when creating these bland designs.
The main character must be made of tissue paper though, as he is down in one hit. This makes sense with the title’s flying fireballs and nasty falls, but even a simple kick will boot you right back to the title screen. All you get for your efforts is the phrase “you did not become devil,” which makes absolutely no sense – it is the only thing that even comes close to a story or narration in this game. Leaderboards, two-player support, or any other modes are noticeably absent as well, and means that the game has limited replayability.
Goinund’s waves of generic enemies will leave players bored rather than scared. When paired with the brain-dead AI and lack of challenge, you’ve got yourself a title that overstays its welcome in no time flat.
Information For new comers in online gambling
Sunday April 28, 2019
Before you choose an online casino to play, it’s most useful to know in regards to the guidelines to observe. There are hundreds of online gambling sites on the internet web. Show yourself on the way to section the nasty and rogue ones. Check out the sportsbook provided below: Determine the terms and conditions Distinctive […]
This review of Goinund was done on the PC. The game was purchased digitally.
Posted 7 hours ago by Casey Scheldin Casey Scheld Reviews, Game Reviews, PC Reviews Goinund Review
The demon onslaughts of Doom and Painkiller have made the jump to Maksim Chudaev’s arena based battler Goinund. There are certainly a lot of targets to take down, but this is one title that lacks the
Posted October 29, 2018 by Casey Scheldin Casey Scheld Reviews, Game Reviews, PC Reviews Black Bart Review
Outside of Rockstar Games’ Red Dead series, the world of Westerns has seen little love in the world of video games as of late. Parmenion Games’ Black Bart sets out to right this wrong with their
Posted October 26, 2018 by Casey Scheldin Casey Scheld Reviews, Game Reviews, PC Reviews Driftpunk Racer Review
Futuristic cyberpunk meets 80s fashion with the release of Speedspark Studio’s Driftpunk Racer. Does it do enough to stand out, or are its retro aesthetics dated in more ways than one?
Posted October 25, 2018 by Johnny Hurricanein Game Reviews, Johnny Hurricane Reviews, PlayStation 4 Reviews Red Dead Redemption 2 Review
After an eight year wait, Rockstar Games returns to the West with Red Dead Redemption 2. Is this game worth your time, or should you check out one of the many other games coming this holiday? Check
The post Goinund Review appeared first on GamersHeroes.Tags: alignment
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domain: game


Adamas Pharmaceuticals Inc (NASDAQ:ADMS) just announced its intention to submit an NDA for its lead Parkinson’s candidate before the year draws to a close. Alongside the announcement came some updated data, so here’s a look at what the data offers in terms of chance-of-approval insight, and what an approval might mean for Adamas and its shareholders going forward.
As ever, let’s take a look at the science behind the drug before we get into the data. We mentioned it’s a Parkinson’s target, but that’s not strictly accurate. The drug aims to treat a condition called dyskinesia – specifically, a type of dyskinesia called Levodopa induced dyskinesia. Levodopa is a generic drug (although it’s sold in various branded forms) that is administered as a standard of care treatment for Parkinson’s disease sufferers. It’s an amino acid supplement, and it stimulates dopamine production post administration. Parkinson’s is caused by a particular type of neuron in the brain dying – the neuron that is responsible for dopamine production. This lack of dopamine translates to the common movement related issues associated with the condition. Levodopa temporarily helps to replenish dopamine, but over a long course of treatment, can itself cause motor related issues. Specifically, the type of dyskinesia that Adamas is targeting with its development candidate, ADS-5102. The drug is an extended release, oral administration capsule, designed to impact plasma levels of what is called amantadine, a dopamine agonist.
So what did the data from the trial show? Well, the clinical side of the study, and the element that supports the NDA, is rooted in three separate phase III trials – EASED, ID and EASELID 3. There is also an ongoing trial called EASELID 2, which is open as a continuation (primarily as a way to gather long term safety data) for any of the patients that took part in the initial trials to continue with their dosing regimen. All three trials measured the change in LID activity compared to a placebo arm using a special measurement system called the Unified Dyskinesia Rating Scale (UDysRS). The EASED trial took the measurement at eight weeks, the EASELID at twelve and twenty-four weeks, and the EASELID 3 at twelve weeks. The data just released relates specifically to the EASELID trial, and reported a positive treatment response across all demographics. The trial hit its primary endpoint, registering a highly significant improvement from baseline in the above mentioned UDysRS in all patients that completed the trial. The drug also met 5 predefined secondary endpoints, and the incidence rate (as measured by comparing the rate of AEs to the already established safety profile of amantadine) was no cause for concern.
So that’s the data and the science, what are we looking for going forward from Adamas as a potential upside catalyst? As mentioned, the company is looking to file an NDA based on the published results before the end of 2016, and this filing (as well as the FDA’s subsequent acceptance of the submission) will serve as the major upside driver heading into H2 2016. There are a few other things worth keeping an eye on, however. The ongoing safety trial (the EASELID 2 trial mentioned above) is set up so that Adamas can collect data on the long term safety profile of this oral administration version of an already approved formulation. As such, the company will want to ensure it maintains an AE rate that is consistent with its earlier phase trialing, and concurrently, that of its control arm. This should be an issue, as there has been no indication to date that the drug causes any concerns outside of those normally regarded as acceptable. It’s worth keeping an eye on, however, as if something comes up then Adamas will have to report it to the FDA and it could impair the drug’s potential from a green light perspective. Cash is also worth watching. Adamas has a few lead pipeline projects underway, and only around $98 million cash on hand (as of March 31, 2016). This should see it through to NDA submission with no issues, but commercialization can quickly burn cash, so it’s likely to require some level of financing before the close of next year.


Delta is a city in Pennsylvania. So far we have accumulated 0 streets in Delta and on these streets we have added 0 real estate properties.
- Federal District
Delta is a borough in York County, Pennsylvania, United States, and one of the southernmost communities in Pennsylvania. The population was 728 at the 2010 census. It is served by the South Eastern School District which provides a public education.


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Wucka-wucka guitar shuffle and serene vocal harmonies dust "Cloud Nine" by The Temptations and provides a wonderful lead-in for the more restrained late night smoky jazz vibes of "Cleo's Apartment" by Marvin Gaye. The Temptations take it a little more symphonic on "Take A Look Around," but the strings create a haunting aural motif that fits in nicely with the rest of the album.
Then it's all about the fusion funkdafied spatter of Grover Washington, Jr. on "Knucklehead," a brilliant chunk of sound that has been judiciously sampled by just about every rapper worth his salt over the past 20 years. "Do It Baby" returns to a more pop oriented vibe, but thanks to a lumbering bass groove buried at its core, it stays true to the sonic emotions that have been percolating up to this point. The album closes with Gaye's atmospheric, falsetto driven lament "Trouble Man."
Devout musicphiles and serious beat junkies will no doubt already own each and every song on this compilation, probably in duplicate, if not triplicate. And much of the music will be familiar not only to the hip-hop generation, but to the old soul crowd, as well. Yet their familiarity is what helps the soundtrack succeed, reveling in the groove and emotional drift with warm sensuality and gritty passion. Yet none of this would be possible if those involved hadn't been in possession of sharp ears and a keen sense of flow. Sure, the folks who created these songs are incomparable artists. But the folks who put this album together are no less artistic. Digging in the crates is one thing. Being able to take what you've found and put it together in such a way as to create a listening experience that you can enjoy over and over again is a rare talent indeed.
1. "T Plays It Cool" - Marvin Gaye
2. "Shake Me, Wake Me (When It's Over)" - Four Tops
3. "Inner City Blues" - Marvin Gaye
4. "Knucklehead" - Grover Washington, Jr.


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The Downtown Farm Stand is a full-service market in downtown Muncie with a seasonal selection of meat, dairy, eggs, produce, bulk foods, and canned goods from Indiana’s finest farms and regional producers. The store is complete with quality organic food as well as offering safe and natural cleaning, personal hygiene and eco-friendly paper products.
The Farm Stand also offers Farm to Table interpretations of classic deli sandwiches and paninis along with some of our own creations, or you can build your own sandwich or panini for dine in or carryout. We make our deli sandwich loaves, sauces, and two of our meats from scratch in house. We offer three house made soups everyday. All sandwiches or paninis can be made into a salad or a wrap. We have organic beer, bottles and draft, and wine available to drink in house or carry out. ALL of our ingredients are organic with many sourced locally.
The Downtown Farm Stand offers a home delivery service of organic fruits and vegetables. With the delivery service you get free delivery, and the ability to add on any items in the grocery store. Farm Stand Delivery offers you an easy way to connect with local organic farms. We give you the freshest highest quality produce from the farmers along with a selection of organic fruits and vegetables that we can’t get locally but are in season.


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Just you! Neither Bud nor any other third party that we work with can see your account information. All of the services that are offered on the Bud app are using open banking technology, which is a secure way of us getting access to your financial information. When you add accounts to the Bud app, we'll direct you to your bank which you will authenticate with directly. Your balances and transactions are then encrypted so that only you can access and read the information.
Only in select circumstances, when you choose to share your data with us will we be able to see any of it. See this article on sharing data to help us fix a bug in the app here for more information.

domain: finance


text:
Units Per Box: 6
Product of Australia
Beef Liver is an excellent reward and training tool. This all natural treat has been the preferred choice for trainers for over 10 years due to its convenience and palatability.
Our treats contain only one ingredient and are perfect for dogs with allergies or those who are on limited ingredient diets.
All Yummi treats contain absolutely NO additives, chemicals or preservatives.
Ingredients: 100% Australian Farmed Beef
Also available in 120g
Analysis: Protein 60.7% – Fat 10% – Fibre 0.2% – Salt 0.4%

domain: pet


text:
New York: Walker & Co., 2004. First paperback edition. Color Pictorial Wraps. Octavo, pp. xiii, 287, indexed, illustrated with b/w photographs. As New. Item #20554
There once may have been 250,000 miles of stone walls in America's Northeast, stretching farther than the distance to the moon. Even though most of them are crumbling today, they contain a magnificent scientific and cultural story. Linking geological history to the early American experience, this book presents a fascinating picture of the land the Pilgrims settled, allowing us to see and understand it with new eyes.

domain: history


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Explore the latest in cerebrovascular hemorrhage, including recent advances in diagnosis and management of spontaneous and iatrogenic bleeding.
This case report describes a man who experienced a hyperacute spontaneous intracerebral hemorrhage when a computed tomography scan was underway.
This meta-analysis evaluates which factors are associated with diffusion-weighted imaging lesions and whether these lesions are associated with functional outcomes among patients with intracerebral hemorrhage.
This secondary analysis of a randomized clinical trial evaluates the differential outcomes of intensive vs standard systolic blood pressure reduction in patients with intracerebral hemorrhage and initial systolic blood pressure of 220 mm Hg or more vs less than 220 mm Hg.
This cohort study compares net risk for ischemic vs hemorrhagic events at 12 months among patients treated with ticagrelor vs clopidogrel during and after percutaneous coronary intervention (PCI) management of acute coronary syndrome (ACS).
This cohort study assesses the association of the COVID-19 pandemic with the incidence of 5 medical emergencies (acute myocardial infarction, ischemic stroke, nontraumatic subarachnoid hemorrhage, ectopic pregnancy, and appendicitis) in 2 US academic medical centers.
This prespecified analysis of a randomized clinical trial investigates the effect of cerebral microbleeds on patients with embolic stroke of undetermined source taking either daily rivaroxaban or aspirin.
This cohort study examines data from original and offspring participants in the Framingham Heart Study to assess the incidence of intracerebral hemorrhage, incidence rates stratified by deep and lobar brain locations, and location-specific risk factors between 1948 and 2016.
This Viewpoint discusses ways to reduce overtriage for patients with neurologic disease and finding ways to care for patients at a distance during the coronavirus disease 2019 pandemic.
This study determines whether selective serotonin reuptake inhibitor use among survivors of primary intracerebral hemorrhage was associated with intracerebral hemorrhage recurrence and decreased severity of depressive symptoms.
This randomized clinical trial examines the differences in recovery, mortality, and other clinical results of endovascular treatment with guideline-based standard medical care vs standard medical care alone provided to patients with cerebral venous thrombosis.
This cohort study in Taiwan compares the clinical outcomes of warfarin use and non–vitamin K antagonist oral anticoagulant use in patients with atrial fibrillation with a history of intracranial hemorrhage using a nationwide cohort with atrial fibrillation.
This systematic review and meta-analysis characterizes the between-study variability in health utility weighting of the modified Rankin Scale in a population of patients with stroke and its implications when applied to the results of a clinical trial.
This cohort-crossover study evaluates the risk of intracerebral hemorrhage during pregnancy and an extended 24-week postpartum period and examines the fetal and maternal outcomes, as well as associated demographic and comorbidity factors.
This meta-analysis assesses the outcomes of the use of warfarin among patients with atrial fibrillation and end-stage renal disease.
This narrative review summarizes randomized clinical trials with negative (vs neutral) outcomes to study why previous acute stroke interventions appeared to cause harm.
This cohort study assesses the association of post–dural puncture headache with postpartum intracranial subdural hematoma in women whose data were in the US Agency for Healthcare Research and Quality National Readmission Database.
Customize your JAMA Network experience by selecting one or more topics from the list below.
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domain: medical


Look into the soul of this race car only if you dare. It’s darker than an event horizon, deep, twisted and snarling.
So menacing was its tendencies, that it pushed two of Supercars’ most skilled drivers to the limit, James Courtney and Garth Tander.
Known as WR 021, the Holden VF Commodore Supercar racer is now for sale through Lloyds Auctions.
Starting life in 2014, WR 021 was the sixth chassis built by Walkinshaw – then the factory-supported Holden Racing Team – for Supercars’ Car of the Future regulations.
The car made its debut at the hands of Garth Tander at Sydney Motorsport Park that same year. At this point, it had not begun its turn to the dark side.
In its early racing career, WR 021 was just like any regular chassis, even claiming a podium at the 2014 Sandown 500. However, come October, things began to turn sour.
On the Saturday for that year’s Bathurst 1000, the chassis was involved in a big crash. Warren Luff was at the wheel when the car suffered a brake failure at the end of Mountain Straight, and he careened into Craig Lowndes. The significant damage meant the car was withdrawn from the Great Race.
While it was thought that that chassis would be irreparable, it was eventually mended and returned to racing service. The next year it scored a Bathurst 1000 podium finish at the hands of Tander and Luff on the way to winning the 2015 Enduro Cup.
However, as its racing career continued into 2016, the chassis began to misbehave, and allegedly reacted unpredictably to set-up changes. It was then parked at the request of Tander, and relegated to duties as a spare chassis, and underwent a full rebuild in the ‘16/’17 off season.
When James Courtney’s primary chassis for 2017 (WR 022) was heavily damaged in a multi-car crash at Symmons Plains, the 2010 Supercars champion moved into WR 021.
Courtney blamed WR 021 for a poor performance in Perth, stating “maybe Garth was right and maybe that car is possessed. Maybe someone here can come and perform an exorcism on it.”
Built when Walkinshaw was still the factory Holden Racing Team, WR 021 achieved five podium finishes during its Supercars career for HRT.
Walkinshaw will prep the car in any livery it raced in during its history, which included special colours for the Bathurst 1000.
The auction begins Monday 30th September at 6pm, though you can already start bidding online. At the time of writing the highest bid on WR 021 stood at $59,000.
If successful in winning the action, delivery for the car is slated for February 2020.
So, are you brave enough to buy this ‘possessed’ racer?


The United Nations Environment Programe (UNEP) views pollution as a major threat to the earth and its inhabitants. UNEP reports that air pollution is the largest cause of disease and premature death in the world, with more than seven million people dying prematurely due to pollution. About 90% of the world population breathes air that contains levels of pollutants that exceed guidelines set by the World Health Organization (WHO). The 2023 “State of the Air” report sponsored by the America Lung Association reveals that nearly 36% of Americans (almost 120 million) live in places with unhealthy levels of air pollution. Furthermore, people of color are disproportionately affected by air pollution, composing 72% of the 18 million Americans living in counties with the worst air quality. One United Nations study claims that exposure to air pollution is the largest cause of disease and premature death in the world, taking the lives of 7 million persons each year. In the United States air pollution cause more deaths each year than murders and car accidents combined.
In his ground-breaking encyclical, Laudato Si, Pope Francis recognizes the pollution problem in a graphic image: “The Earth, our home, is beginning to look more and more like an immense pile of filth.” In many places, “beautiful landscapes are now covered with rubbish” and landfills are overflowing. The pope links the pollution problem with a “throw away culture” that casually disposes of everything not immediately useful. He cites one example: “Most of the paper we produce is thrown away and not recycled.” He laments that our industrial system “has not yet managed to adapt a circular model of production capable of preserving resources for present and future generations. To counteract the throw away culture, we should limit as much as possible “the use of non-renewable resources, moderating their consumption, maximizing their efficient use, reusing and recycling them.”
In 2021, Francis launched a seven-year “Laudato Si Action Plan” with seven specific goals beginning with a new effort to hear the cries of the earth. In announcing the plan, the pope said we must resist the temptation to be “predators of resources,” adding “from God’s hands we have received a garden, we cannot leave a desert to our children.”
By highlighting recycling as a response to the cries of the earth, Francis provides moral support for prominent environmental agencies in the U.S. urging more Americans to recycle. For example, the Environmental Protection Agency (EPA) reports that only about 32% of Americans recycle regularly today. This is up from less than 7% in 1960 but still far from what is needed to preserve our common home. The EPA claims that “reused activities” account for 681,000 jobs and $37 billion in wages. The agency highlights the annual November 15 celebration of “America Recycles Day” as a way of encouraging all Americans to “recycle right” on a regular basis. Recycling has many benefits: reducing the amount of waste sent to landfills and incinerators; conserving natural resources; preventing pollution; saving energy; conserving valuable resources; and providing new jobs. Finally, the EPA encourages all Americans to learn how to recycle properly in their local communities.
With Pope Francis, we ask God to “bring healing to our lives that we may sow beauty, not pollution and destruction.”
How can I improve my recycling practices?
About the Author
Fr. James J. Bacik has served as a priest of the Diocese of Toledo since his ordination in 1962. He is a widely regarded theologian, writer, lecturer and pastor who served as campus minister and adjunct professor of humanities at the University of Toledo for more than 30 years. Fr. Bacik is an AUSCP member. Visit his website at frjimbacik.org.


MINNEAPOLIS (WCCO) -- Former Minnesota Lieutenant Governor Sandy Keith has passed away.
According to the Minnesota Legislature website, Keith passed away on Saturday. The Rochester native was also a retired Minnesota Supreme Court Chief Justice.
Keith was almost 92 years old.
This is a developing story, please check back for updates.
for more features.


text:
Ultimate No Trick Needle Through Arm by Seamus Seanachaoi - DVD
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domain: hobby


text:
Carte de visite photograph by Maull & Co, London, of William Whewell FRS (1794-1866), one of the most influential scientific minds of the 19th century. A carpenter's son from Lancaster, Whewell won a scholarship to Cambridge University in 1812. In 1819 he published his first textbook, 'An Elementary Treatise on Mechanics', which became the standard text used by students at Cambridge. From 1820-1840 he taught and wrote extensively on astronomy, geology, mechanics, mineralogy, theology and architecture, but is best known for his writing on the history and philosophy of science. He was President of the British Asociation for the Advancement of Science and of the Geological Society, and from 1841until his death he was Master of Trinity College, Cambridge.
© Science Museum / Science & Society Picture Library

domain: library


US 4102625 A
A spinneret holder has a pressurizable chamber formed between a cupped base part having a rim centered on an axis and a cover part having a periphery snugly interfittable with the rim. A plurality of spinnerets is provided in the cover part so that a mass to be spun can be introduced into the chamber and exit as filaments from the spinneret. A rod or bolt lying on the axis has threads anchored in one of the parts and the other part is formed at the axis with the throughgoing holes through which the rod passes. Thus an element such as a head or nut on the rods bears axially on the other part and can press the rim of the base part nad periphery of the cover part axially tightly together.
1. A spinneret holder comprising:
a cupped base part having a rim centered on an axis;
a cover part having a periphery snugly interfittable with said rim and defining with said base part a generally closed chamber centered on said axis;
a plurality of spinnerets mounted on said cover part;
means for introducing a mass to be spun into said chamber and for expelling said mass as filaments from said chamber through said spinnerets;
a rod lying generally on said axis and having threads anchored in one of said parts, the other part being formed at said axis with a throughgoing hole through which said rod passes; and
an element on said rod bearing axially on said other part only immediately adjacent said hole thereof and pressing said rim and said periphery axially tightly together, said other part having an axial face turned away from said one part and engaged only by said element said parts being pressed axially together at said rim and periphery exclusively by means of said rod and element.
2. The holder defined in claim 1, wherein said base part is formed with a radially throughgoing inlet offset from said axis, said means for introducing a mass including a conduit connected to said base part at said inlet for feeding a mass to be spun under pressure to said chamber.
3. The holder defined in claim 1, wherein said rim is formed with a shoulder normally radially surrounding said periphery.
4. The holder defined in claim 1, wherein said rod has one threaded end formed with said threads and anchored in said one part and an opposite threaded end, said element being a nut threaded onto said opposite end of said rod.
5. The holder defined in claim 1, wherein said cover part is concave toward said base part.
6. The holder defined in claim 1, wherein said cover part is formed with a plurality of throughgoing axially extending holes each receiving a respective one of said spinnerets, said cover part being formed at each of said throughgoing holes with an inwardly open groove and being provided in each of said grooves with a respective elastomeric seal ring resiliently engaging the respective spinneret.
7. The holder defined in claim 1, wherein said chamber is flared toward said cover part.
8. The holder defined in claim 1, wherein both of said parts are substantially formed as bodies of revolution centered on said axis.
9. The holder defined in claim 8, wherein said periphery and said rim are substantially circular and each have a face lying in a respective plane substantially perpendicular to said axis, said faces being flatly axially engageable with each other.
10. The holder defined in claim 9, wherein said base part is formed at said rim with a cylindrical surface extending parallel to said axis from the respective face, said periphery being receivable within said surface.
11. The holder defined in claim 1, wherein said cover part has an axial face turned toward said base part and engaged only with said spinnerets and with said rim.
12. A spinneret holder comprising:
a cupped base part having a rim centered on an axis and formed by a flat substantially planar and annular base surface lying in a plane substantially perpendicular to said axis and a substantially cylindrical side surface substantially parallel to said axis;
an at least partially resiliently deformable cover part concave toward said base part and having a periphery formed by a flat substantially planar and annular face surface flatly engageable with said base surface and a substantially cylindrical edge surface of substantially the same diameter as said side surface and juxtaposable therewith, said parts together forming a closed chamber on said axis;
a plurality of spinnerets mounted on said cover part;
means including an inlet through said base part opening into said chamber for introducing a mass into said chamber and for exiting of said mass as filaments from said spinnerets;
a rod lying generally on said axis and having one end anchored in one of said parts, the other part being formed at said axis with a throughgoing hole and said rod having another end extending axially through said hole; and
means including an element on said rod bearing axially on said other part at said hole for pressing said parts axially together and for simultaneously deforming at least said cover part and thereby pressing said rim and periphery tightly together.
The present invention relates to a spinneret holder. More particularly this invention concerns such a holder in which a plurality of spinnerets can be mounted.
In order to form a synthetic-resin yarn it is standard practice to fit a plurality of spinnerets in a holder. The holder has a hollow interior defining a closed chamber and the spinnerets are mounted in one wall of the holder. A mass to be spun is forced under pressure into the holder so as to issue from the spinnerets as a plurality of filaments which can be later spun and treated in a manner well known in the art.
A multijet coupling or spinneret holder is known where the spinnerets are all mounted in a so-called cover plate that is secured by means of a complex clamping ring having a plurality of screws to a base part. Together the cover part and base part form the above-mentioned closed chamber which is filled with the pressurized mass to be spun.
Such an arrangement has the considerable disadvantage that in case of clogging of any of the spinnerets or jets it is necessary to disassemble the entire holder and clear the blocked spinneret or spinnerets. Such an operation is a relatively lengthy task in the known systems wherein the clamping arrangement is quite complex.
It has been suggested to provide a simpler clamping means, however, none has proved itself useful in practice since the pressure of the mass to be spun is relatively high, and leakage cannot be tolerated. Thus recourse has always been had to the above-mentioned type of relatively complex clamping rings using a plurality of tightenable clamping elements such as bolts. This of course leads to the problem of unequal clamping pressure around the seam or joint between the cover and base part, with concomitant leakage. Furthermore this arrangement is normally complicated by the necessity of clamping between the two parts a screen or filter cloth intended to prevent particles or the like in the spun mass from reaching the spinnerets and blocking them.
It is therefore an object of the present invention to provide an improved multijet coupling or spinneret holder.
Another object is the provision of an improved spinneret holder which can be easily disassembled for servicing.
Yet another object is to provide such a spinneret holder which when closed forms an excellent tight seal.
Yet another object of this invention is the provision of a spinneret holder which can easily clamp a filter screen or cloth between the inlet for the mass to be spun and the spinneret.
These objects are attained according to the present invention in a spinneret holder comprising a cupped base part having a rim centered on an axis and a cover part having a periphery snugly interfittable with the rim and defining with the base part a generally closed chamber centered on the axis. A plurality of spinnerets is mounted in the cover part so that a mass to be spun can be introduced into the chamber and exit as filaments from the spinnerets. A rod lies generally on the axis of the base and cover part and has threads anchored in one of these parts. The other part is formed at the axis with a throughgoing hole through which the rod passes. An element on the rod bears axially on the other part and presses the rim of the base part and the periphery of the cover part axially tightly together.
Thus the spinneret holder according to the present invention is very tightly sealed in an extremely simple manner. Since the rim of the base part is centered on the axis and the periphery of the cover part is snugly interfittable with this base pressure brought to bear by the element on the rod will insure perfectly even sealing all around the seam or joint between the two parts.
According to another feature of this invention the rod is threaded at its lower end into the base part and has a threaded upper end on which a nut constituting the element is threaded. Thus the rod constitutes a stud, and rotation of the nut will serve to hold the cover and base part tightly together. It is of course within the scope of this invention to anchor the rod in the cover part and have it project through a hole in the base part, and similarly to form the rod as a bolt so that the element is merely the head of the bolt.
In accordance with yet another feature of this invention the base part is formed with a radially throughgoing inlet which is offset from the axis. Means is provided including a conduit connected to the base part at the inlet for feeding a mass to be spun under pressure to the chamber defined between the base part and cover part. This chamber is upwardly flared in the base part toward the cover part.
The cover part according to yet another feature of the present invention is downwardly concave or dished toward the base part and has at its periphery a planar face lying in a plane perpendicular to the axis of the assembly. In addition the base part has a stepped rim formed with a shoulder between a face lying in a plane perpendicular to the axis and another surface lying on a cylinder centered on the axis. Thus the cover part, which extends up beyond the base part, can be recessed in the base part and form an extremely tight and neat seal therewith.
According to further features of this invention there is provided at the joint between the two parts an annular seal ring. This seal ring may be received within a radially outwardly open groove formed in the outer periphery of the cover part. Similarly this cover part is formed at its axially central throughgoing hole with an inwardly open groove in which is provided another such seal ring resiliently engaging the rod. The cover part is also formed in accordance with this invention with a plurality of throughgoing holes each receiving a respective spinneret and each formed with an inwardly open groove in which is received a respective elastomeric seal ring that resiliently engages the respective spinneret. These spinnerets have enlarged ends inside the chamber, and are resiliently held in place by the respective seal rings. No particular clamping arrangement is necessary for the spinnerets since during operation pressurization of the chamber will hold them perfectly in place.
Finally according to this invention the chamber which is largely formed by the base part is of frustoconical shape and flares toward the cover part. The inlet opens radially into this chamber at a location spaced from the cover part so that a good mixing of the mass to be spun is obtained. Similarly a filter screen or the like can easily be clamped between the cover part and base part, so that its removal is effected simply by loosening the above-mentioned rod. This arrangement is particularly useful for the production of cellulosic fibers by the viscose process.
The novel features which are considered as characteristic for the invention are set forth in particular in the appended claims. The invention itself, however, both as to its construction and its method of operation, together with additional objects and advantages thereof, will be best understood from the following description of a specific embodiment when read in connection with the accompanying drawing.
FIG. 1 is an axial section through the spinneret holder according to this invention;
FIG. 2 is a large-scale view of a detail of FIG. 1; and
FIG. 3 is a large-scale view of a detail of FIG. 2.
As shown in FIG. 1 a spinneret holder according to this invention comprises an upwardly cupped base part 1 and a downward concave cover part 2 together defining an upwardly flared frustoconical chamber 3. A mass to be spun can be introduced into this chamber 3 via a conduit 4 opening at an inlet 5 formed in the base part 1 adjacent the bottom end of the chamber 3 thereof. The cover part 2 carries a plurality of spinnerets 6 and is secured to the base part 1 by means of a rod 7. A screen 8 to filter out particles from the mass introduced to the chamber 3 is clamped between the cover 2 and base 1. The rod 7 has a vertical central axis 9 and the cover 1 and base 2 are both formed substantially as bodies of revolution centered on this axis 9.
At its lower end the rod 7 has a threaded region 23 which is received in a threaded hole 10 formed on the axis 9 in the bottom of the base part 1. The cover 2 is formed centrally with a cylindrical hole 11 and in this hole 11 with a radially inwardly open groove 12 in which is provided an O-ring 13 that bears resiliently on the outer surface of the rod 7. At its upper end this rod 7 is provided with a head or nut 14 which when rotated about the axis 9 bears axially downwardly on the cover part 2 so as to secure it to the base part 1.
The cover part 2 is formed as a portion of a hollow sphere and is concave downwardly toward the base part 1. This cover part 2 has an array of throughgoing cylindrical holes 15 extending perfectly parallel to the axis 9 as shown in FIG. 3 and having at the underside of the cover 2 a cylindrical counterbore 17 adapted to receive a radially extending flange on the respective spinneret 6. Furthermore each of these throughgoing cylindrical bores 15 is formed with a radially inwardly open groove 18 provided with a respective O-ring 19 that bears resiliently on the outside of the cylindrical spinneret 6. The O-rings 19 alone serve to hold the spinnerets 6 in place, and once the arrangement is in operation pressurization of the chamber 3 by means of the conduit 4 insures that the spinnerets 6 will remain tightly in place.
The base part 1 is formed at its upper end with a rim constituted by a pair of surfaces 20 and 24. The surface 24 lies in a plane perpendicular to the axis 9 and the surface 24 lies on a cylinder centered on the axis 9 and extending at right angles to the surface 24. In addition the cover 2 has a rim formed by a pair of surfaces 25 and 26 complementary to the surfaces 20 and 24, respectively, and snugly fitting therewith. The outer diameter of the cover 2 at the surface 25 is the same as the inner diameter of the base 1 at the surface 20. In addition the cover 2 is formed on its outer periphery at the surface 25 with an outwardly open groove 21 in which is received an O-ring 22 that is of elastic material and resiliently engages the surface 20. The cover 2 is made at least partially of resiliently deformable material so that as the portion 14 of the rod 9 is rotated it will be pressed tightly down into planar surface engagement between the surfaces 24 and 26 with the base 1 and will form a very tight seal therewith.
The arrangement according to the present invention is therefore extremely simple in construction and sure in use. The filter cloth 8 clamped between the surfaces 24 and 26 is very tightly held in place and in no way interferes with the seal formed at these surfaces, especially since the O-ring 22 serves to back up the seal. Dismantling of the holder is a relatively simple process, easily effected by rotation of the element 14 about the axis 9.
It will be understood that each of the elements described above, or two or more together, may also find a useful application in other types of structures differing from the types described above.
While the invention has been illustrated and described as embodied in a spinneret holder, it is not intended to be limited to the details shown, since various modifications and structural changes may be made without departing in any way from the spirit of the present invention.
Without further analysis, the foregoing will so fully reveal the gist of the present invention that others can by applying current knowledge readily adapt it for various applications without omitting features that, from the standpoint of prior art, fairly constitute essential characteristics of the generic or specific aspects of this invention.


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But even if you’re not trying to lose weight, the keto meal plans might appeal to you. By limiting sugars and processed grains, you lower your risk of type 2 diabetes. Eating an array of heart-healthy fats, like nuts, olive oil and fish, can decrease your risk of heart disease. And while some people stick to a super strict keto diet, with 75 percent of their diet coming from fat, 20 percent from protein and just five from carbs, even a less intense, modified version can help you reap the keto diet’s benefits.
One review, published in April 2016 in The American Journal of Medicine, looked at five research trials on overweight and obese people and found that after one year those who followed a Mediterranean diet lost as much as 11 pounds (lbs) more than low-fat eaters. (6) (They lost between 9 and 22 lbs total and kept it off for a year.) But that same study found similar weight loss in other diets, like low-carb diets and the American Diabetes Association diet. The results suggest, the researchers say, that “there is no ideal diet for achieving sustained weight loss in overweight or obese individuals.”
The modified Atkins diet reduces seizure frequency by more than 50% in 43% of patients who try it and by more than 90% in 27% of patients. Few adverse effects have been reported, though cholesterol is increased and the diet has not been studied long term. Although based on a smaller data set (126 adults and children from 11 studies over five centres), these results from 2009 compare favorably with the traditional ketogenic diet.
Ay gatas masamang para sa mga diabetic
The ketogenic diet has recently become very popular, and many food companies want to cash in by putting a “ketogenic” or “low carb” label on a new product. Be very cautious of special “keto” or “low-carb” products, such as pastas, chocolate bars, energy bars, protein powders, snack foods, cakes, cookies and other “low carb” or “ketogenic” treats. Read all labels carefully for natural low carb ingredients. The fewer ingredients the better.
Infants and patients fed via a gastrostomy tube can also be given a ketogenic diet. Parents make up a prescribed powdered formula, such as KetoCal, into a liquid feed. Gastrostomy feeding avoids any issues with palatability, and bottle-fed infants readily accept the ketogenic formula. Some studies have found this liquid feed to be more efficacious and associated with lower total cholesterol than a solid ketogenic diet. KetoCal is a nutritionally complete food containing milk protein and is supplemented with amino acids, fat, carbohydrate, vitamins, minerals and trace elements. It is used to administer the 4:1 ratio classic ketogenic diet in children over one year. The formula is available in both 3:1 and 4:1 ratios, either unflavoured or in an artificially sweetened vanilla flavour and is suitable for tube or oral feeding. Other formula products include KetoVolve and Ketonia. Alternatively, a liquid ketogenic diet may be produced by combining Ross Carbohydrate Free soy formula with Microlipid and Polycose.
Fat isn’t unlimited either. As with wine, it's possible to get too much of a good thing when it comes to healthy fats. The American Heart Association points out that while the Mediterranean diet meets heart-healthy diet limits for saturated fat, your total fat consumption could be greater than the daily recommended amount if you aren't careful. That’s 65 g per day. (32)
Ketogenic diets usually do cause weight loss and may improve insulin sensitivity in patients with diabetes. In fact when compared to a low-fat diet a ketogenic diet appears to achieve greater long term reductions in body weight. However, the success long term is dependent on your ability to adapt your dietary habits once you start to introduce a more balanced and healthy approach to eating.
Que es la comida Keto
In addition, no statement on this website has been evaluated by the Food and Drug Administration, and any product mentioned or described on this website is not intended to diagnose, treat, cure, or prevent any disease. If you purchase anything through a link on this website, you should assume that we have an affiliate relationship with the company providing the product or service that you purchase, and that we will be paid in some way. We recommend that you do your own independent research before purchasing anything.
Sino ang nagmamay-ari Zoes Kitchen
Ang ideya na kumain ng isang batya ng ice cream upang makayanan ang pagkabalisa ay naging isang bit cliche. Kahit na ang ilan ay hindi na kailangan ng isang batya ng chocolate swirl upang matulungan ang kanilang mga sarili na muli, mukhang may sistematikong pagkakaiba sa paraan ng mga tao na makayanan ang mga pangyayari na masakit, na may mas malamang na makahanap ng pagkaalipin sa pagkain kaysa iba.
Paano mo malalaman kung youve hit ng pagbaba ng timbang talampas
The aim of ketogenic diets is to send the body into a state of ‘ketosis’ by using a very strict low-carb diet. This umbrella term can include diets such as the Atkins diet, Dukan diet and LCHF (low carb, high fat) diets such as the banting diet, although the ratios of fat, protein and carbs and other specific features of each diet (e.g. ‘phases’) can vary.
In the 1960s, medium-chain triglycerides (MCTs) were found to produce more ketone bodies per unit of energy than normal dietary fats (which are mostly long-chain triglycerides). MCTs are more efficiently absorbed and are rapidly transported to the liver via the hepatic portal system rather than the lymphatic system. The severe carbohydrate restrictions of the classic ketogenic diet made it difficult for parents to produce palatable meals that their children would tolerate. In 1971, Peter Huttenlocher devised a ketogenic diet where about 60% of the calories came from the MCT oil, and this allowed more protein and up to three times as much carbohydrate as the classic ketogenic diet. The oil was mixed with at least twice its volume of skimmed milk, chilled, and sipped during the meal or incorporated into food. He tested it on 12 children and adolescents with intractable seizures. Most children improved in both seizure control and alertness, results that were similar to the classic ketogenic diet. Gastrointestinal upset was a problem, which led one patient to abandon the diet, but meals were easier to prepare and better accepted by the children. The MCT diet replaced the classic ketogenic diet in many hospitals, though some devised diets that were a combination of the two.
In terms of weight loss, you may be interested in trying the ketogenic diet because you’ve heard that it can make a big impact right away. And that’s true. “Ketogenic diets will cause you to lose weight within the first week,” says Mattinson. She explains that your body will first use up all of its glycogen stores (the storage form of carbohydrate). With depleted glycogen, you’ll drop water weight. While it can be motivating to see the number on the scale go down (often dramatically), do keep in mind that most of this is water loss initially.
AG Matcha 🍵 Special: – 1T matcha – 1/2c coconut milk – 1 1/2T @perfectketones C8 MCT oil – 1T raw cacao butter – 1T grass-fed butter – 1 scoop @perfectketones vanilla collagen – 12oz boiling water – 1/4t vanilla bean powder – blend _ Taking some time off coffee and replacing with this bad boy 🍵 this is the type of thing I’ll be having on my “modified carnivore” diet. Also oils, micro greens, leafy greens, avocado.
Ang ilang mga kababaihan ay pipiliin na kumuha ng tuluy-tuloy na birth control na tabletas. Ang mga sikat na pangalan ng tatak ay kasama ang Seasonale, Seasonique, at Yaz. Kung gagamitin mo ang ganitong uri ng tableta, patuloy mong dadalhin ang lahat ng mga aktibong tabletas sa loob ng tatlong buwan, kasunod ng isang linggo ng di-aktibo na mga tabletas. Bagaman maaari kang magkaroon ng pagtutok sa pagitan ng mga buwan, ang iyong panahon ay maaaring dumating apat na beses bawat taon sa mga linggo na may mga hindi aktibo na tabletas. Ito ay hindi pangkaraniwan para sa mga tao sa injectable birth control upang makaranas din ng kakulangan ng mga panahon.
After initiation, the child regularly visits the hospital outpatient clinic where they are seen by the dietitian and neurologist, and various tests and examinations are performed. These are held every three months for the first year and then every six months thereafter. Infants under one year old are seen more frequently, with the initial visit held after just two to four weeks. A period of minor adjustments is necessary to ensure consistent ketosis is maintained and to better adapt the meal plans to the patient. This fine-tuning is typically done over the telephone with the hospital dietitian and includes changing the number of calories, altering the ketogenic ratio, or adding some MCT or coconut oils to a classic diet. Urinary ketone levels are checked daily to detect whether ketosis has been achieved and to confirm that the patient is following the diet, though the level of ketones does not correlate with an anticonvulsant effect. This is performed using ketone test strips containing nitroprusside, which change colour from buff-pink to maroon in the presence of acetoacetate (one of the three ketone bodies).
Maaari kang uminom ng kape habang nag-aayuno
Cheese, if you can tolerate it, can also be purchased in bulk. Many stores offer store-brand cheese in large bricks. You’ll need to make sure to read the labels before you purchase any cheese. Make sure that when you eat cheese to eat some fiber (salad or raw veggies) as well. Having large blocks of your favorite cheeses on hand can make it easy to grab a quick snack between meals.
Early studies reported high success rates; in one study in 1925, 60% of patients became seizure-free, and another 35% of patients had a 50% reduction in seizure frequency. These studies generally examined a cohort of patients recently treated by the physician (a retrospective study) and selected patients who had successfully maintained the dietary restrictions. However, these studies are difficult to compare to modern trials. One reason is that these older trials suffered from selection bias, as they excluded patients who were unable to start or maintain the diet and thereby selected from patients who would generate better results. In an attempt to control for this bias, modern study design prefers a prospective cohort (the patients in the study are chosen before therapy begins) in which the results are presented for all patients regardless of whether they started or completed the treatment (known as intent-to-treat analysis).
The day before admission to hospital, the proportion of carbohydrate in the diet may be decreased and the patient begins fasting after his or her evening meal. On admission, only calorie- and caffeine-free fluids are allowed until dinner, which consists of "eggnog"[Note 8] restricted to one-third of the typical calories for a meal. The following breakfast and lunch are similar, and on the second day, the "eggnog" dinner is increased to two-thirds of a typical meal's caloric content. By the third day, dinner contains the full calorie quota and is a standard ketogenic meal (not "eggnog"). After a ketogenic breakfast on the fourth day, the patient is discharged. Where possible, the patient's current medicines are changed to carbohydrate-free formulations.
It is possible to combine the results of several small studies to produce evidence that is stronger than that available from each study alone—a statistical method known as meta-analysis. One of four such analyses, conducted in 2006, looked at 19 studies on a total of 1,084 patients. It concluded that a third achieved an excellent reduction in seizure frequency and half the patients achieved a good reduction.
A systematic review in 2018 looked at 16 studies on the ketogenic diet in adults. It concluded that the treatment was becoming more popular for that group of patients, that the efficacy in adults was similar to children, the side effects relatively mild. However, many patients gave up with the diet, for various reasons, and the quality of evidence was inferior to studies on children. Health issues include high levels of low-density lipoprotein, high total cholesterol, and weight loss.
Paano u malaman kapag ur sa ketosis
Fasting venous blood samples were collected at weeks 0 and 12 for total cholesterol, HDLc, LDLc, triacylglycerol and glucose. Venous blood samples for glucose, lipid and lipoprotein analysis were collected into EDTA-containing (1 g/l) tubes from all subjects after a 12 h overnight fast at the beginning of the study and at the end of each dietary period. Plasma was obtained by low-speed centrifugation for 15 min at 4°C within 1 h of venepuncture. Plasma cholesterol and TAG levels were determined by enzymatic techniques. HDL-cholesterol was determined after precipitation with fosfowolframic acid LDL-cholesterol concentration was calculated using the Friedewald formula. Plasma glucose was measured by the glucose oxidase method. To reduce interassay variation, plasma was stored at -80°C and analysed at the end of the study.
Maaari Clenbuterol build kalamnan
When you start the keto diet, you are entering a new world of eating. And nowhere is that more apparent than at the supermarket. Suddenly, all of your stand-by foods like macaroni and cheese, pasta and bread are no longer on your shopping list. When you go shopping for the first few times you may feel like a fish out of water. However, with a bit of practice, you’ll feel just as comfortable as you were with your previous shopping lists.
Upang maunawaan kung paano gumagana ang ketogenic diyeta, kailangan mong maunawaan ketosis, ang proseso kung saan ang iyong katawan ay gutom sa glucose para sa gasolina at dapat tumingin sa mga pinagkukunang taba sa halip. Kadalasan, pino-fuel mo ang iyong katawan sa pamamagitan ng pagbibigay ito ng glucose sa anyo ng mga carbs, na matatagpuan sa harina, butil, gulay, tsaa, mga produkto ng dairy, at prutas.
Maaari mataas na antas ng asukal sa maging sanhi ng Pagkahilo
It works directly on stubborn fat deposited in the different parts of your body. It controls weight gain and promotes safely store to help you get require body mass. Ketosis process simply activates the brain cells that control fat. It works as a source of energy. Moreover, its effective working process takes good care of metabolism that gives you better control over appetite and cravings.
Ang L-theanine ay nagtataas ng aktibidad ng alpha wave sa utak na nagtataguyod ng relaxation. Ang mga alon ng Alpha ay tumaas habang natutulog, kaya sa ilang mga paraan ang L-theanine ay tumutulong sa utak na simulan ang proseso ng pagtulog. Ang L-theanine ay nagdaragdag din sa produksyon ng iba pang mga neurotransmitters tulad ng dopamine, GABA, at serotonin, na maaaring mapabuti ang mood at hikayatin ang pagtulog.
Gaano katagal ang isang tao ay nakakahawa sa C diff
Benefits It packs lycopene, a powerful antioxidant that is associated with a reduced risk of some cancers, like prostate and breast. Other components in tomatoes may help reduce the risk of blood clots, thereby protecting against cardiovascular disease, according to a review published in December 2013 in the journal Annual Review of Food Science and Technology. (9,10)
keto almond flour keto asparagus keto avocado keto bacon keto baking keto beef keto bread keto Brussels sprouts keto cakes keto cauliflower keto cheesecake keto chicken recipes keto chocolate keto cocktail keto coconut flour recipes keto cookies keto donuts keto green beans keto muffins keto mug cakes keto nuts keto pancakes keto pecans keto pie keto pizza keto pork keto pudding keto pumpkin spice keto seafood keto veggies


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As soon as you buy a Put or Call option, three numbers appear on the right top side of the chart:
Total investment: how much you have invested into a deal
Expected Profit: possible result of the transaction if the chart point at the expiration line ends up at the same place where it is now.
Profit after Sale: If it is red, it shows you how much of the invested amount you will lose your balance after sale. If it is green, it shows you how much profit you will get after sale.
Expected Profit and Profit after Sale are dynamic, as they change depending on several factors including current market situation, how close the expiration time is and the current price of the asset.
Many traders sell when they aren’t sure that the transaction will give them a profit. The selling system gives you the chance to minimize losses on doubtful options.
If you are using Iplay Binary platform for the first time and if you don’t have much experience, you can start with our video tutorials. You can train on your practice balance, and then continue trading with real funds. You can also find information about trading on the pages of Iplay Binary Blog.
Detailed information of each instrument is stated below.
Please note that you can only sell an option when there is more than 15 seconds before expiration for Turbo options.
For Binary options the Sell button is available from 30 minutes until expiration to 2 minutes until expiration.
If you trade Digital Options, Sell button is always available.
Over-the-counter (OTC) is a trading method that is available when the markets are closed. When trading OTC assets, you get quotes that are generated automatically on the broker’s server in a way that maintains equilibrium between buyers and sellers.
Every Friday at 21:00 and every Monday at 00:00 am (GMT time) Iplay Binary is switching from market trading to OTC trading and from OTC trading to market trading.
New CFD types available on the Iplay Binary trading platform include CFDs on stocks, Forex, indices, CFDs on commodities and cryptocurrencies, ETFs.
The trader’s goal is to predict the direction of the future price movement and capitalize on the difference between current and future prices. CFDs react just like a regular market, if the market goes in your favor then your position is closed In The Money. In case market goes against you, your deal is closed Out Of The Money. The difference between Binary or Digital Options and CFD trading is that your profit depends on the difference between entry price and closing price.
In CFD trading there is no expiration time but you are able to use a multiplier and set stop/loss and trigger a market order if the price gets a certain level.
CFD trading offers the usage of a multiplier which can help a trader to control the position that exceeds the amount of money invested in it. The potential profitability (as well as risks) will also be magnified. Investing $100 a trader may get the return that is comparable to a $1000 investment. That’s the opportunity a multiplier can offer. However, remember that the same goes with potential losses as these would be multiplied as well.
If a trader opens a long position, the profit is calculated according to the formula: (Closing price / Opening price – 1) x multiplier x investment. If a trader opens a short position, the profit is calculated according to the formula (1-closing price/opening price) x multiplier x investment
For example, AUD / JPY (Short position): Closing price: 85.142 Opening price: 85.173 Multiplier: 2000 Investment: $2500 The profit is (1-85.142 / 85.173) X 2000 X $2500 = $1.819.82
Digital Options trading is similar to Binary Options trading. The main distinctive feature is the profitability and the risks of each deal that depend on a manually chosen strike price on the right side of the chart.
– Potential profit on Digital Options can be up to 900%. However, an unsuccessful trade will result in loss of the investment.
– The closer strike price is to the current price of the asset – the lower your risks and potential profit are
Note that digital options will expire-in-the-money only if the actual price is not identical to the strike one. For call options it should exceed the strike price by at least one pip, for put options it should fall behind the strike price by at least one pip.
Binary options trading involves deciding whether the price of the underlying asset is going to increase or decrease. If you choose Call option: you get profit if the closing price is higher than opening price. If you choose Put option: you get profit if the closing price is lower than the opening price.
However, if you have incorrectly predicted the price movement (upwards or downwards) of the underlying asset, you will incur a loss of 100% of your invested amount.
Call Option: closing price > opening price
Put Option: closing price < opening price
This type of trading offers only two outcomes: you either get profit or lose your investment only.
It does not matter how significantly price changes. If the closing price will be equal to opening price, your initial investment into a deal will be returned back to your balance.


NEW AUTOMATED STATION FOR COLLECTION OF CELL CULTURES
Microbiological laboratories for collection of cell cultures.
This new station automates the time-consuming, difficult constricting procedure.
Test-tubs with the following dimensions
– Outside diameter: 14 – 14.5 mm
– Length : 128 – 136 mm
– Wall thickness: 1 mm
can be constricted to a diameter of 0.2 mm.
The test-tube is constricted to a capillary with controlled dimensions. The constrictor makes it possible, that the prepared „cell culture“ can be sealed after the preservation by freeze drying under vacuum.
Advantages of CONSTRICTOR
- CONSTRICTOR uses normal test-tubs and no expensive special glass.
- CONSTRICTOR supplies fast and precise results.
- CONSTRICTOR is simple and easy to use and has a compact form.
CONSTRICTOR makes the cost effective collection of cell cultures possible.


The spectral response of molecular probes strongly depends on the surrounding environment. A successful approach to computational spectroscopy of systems in the condensed phase consists of resorting to focused models, where the focus is on a specific portion of the system, which is described at the Quantum Mechanical (QM) level, whereas the remaining portion is treated classically, through ad-hoc Molecular Mechanics (MM) force-fields . In case of solvated systems, Polarizable QM/MM approaches, where the mutual polarization between QM and MM layers is considered are particularly successful [2-10]. On the other hand, the computational spectroscopy of complex plasmonic nanostructured materials re- quires alternative approaches, which can appropriately model environments at resonance with the external probing field [11-14]. I will discuss the most recent contributions of our group in this field, by also resorting to pilot applications which highlight the methods’ potentialities.
 H. M. Senn, and W. Thiel, Angew. Chem. Int. Ed. 2009, 48, 1198.
 T. Giovannini, F. Egidi, and C. Cappelli, Chem. Soc. Rev. 2020, 49, 5664.
 T. Giovannini, F. Egidi, C. Cappelli, Phys. Chem. Chem. Phys. 2020, 22, 22864.
 T. Giovannini, A. Puglisi, M. Ambrosetti, C. Cappelli, J. Chem. Theory Comput. 2019, 15, 2233.
 T. Giovannini, P. Lafiosca, C. Cappelli, J. Chem. Theory Comput. 2017, 13, 4854.
 T. Giovannini, L. Grazioli, M. Ambrosetti, C. Cappelli, J. Chem. Theory Comput. 2019, 15, 5495-5507.
 T. Giovannini, M. Ambrosetti, C. Cappelli, J. Phys. Chem. Lett. 2019, 10, 5823-5829.
 F. Egidi, S. Angelico, P. Lafiosca, T. Giovannini, C. Cappelli, J. Chem. Phys. 2021, 154, 164107.
 P. Lafiosca, S. Gómez, T. Giovannini, C. Cappelli, J. Chem. Theory Comput. 2022, 18, 1765.
 M. Ambrosetti, S. Skoko, T. Giovannini, C. Cappelli, J. Chem. Theory Comput. 2021, 17, 7146.
 T. Giovannini, M. Rosa, S. Corni, C. Cappelli Nanoscale 2019, 11, 6004.
 Giovannini, L. Bonatti, M. Polini, C. Cappelli J. Phys. Chem. Lett. 2020, 11, 7595.
 L. Bonatti, L. Nicoli, T. Giovannini, C. Cappelli Nanoscale Adv. 2022, 4, 2294.
 T. Giovannini, L. Bonatti, P. Lafiosca, L. Nicoli, M. Castagnola, P. Grobas Illobre, S. Corni, C. Cappelli
ACS Photonics 2022, 9, 3025.


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Son defends Mourinho ahead of Europa League clash
Tottenham Hotspur forward Son Heung-min defended manager Jose Mourinho in a pre-match press conference on Wednesday, ahead of the Europa League team's clash with Wolfsberger on Thursday.
Speaking ahead of the match against Wolfsberger, Son answered a series of questions about Spurs' drop in the table this year, falling from first place in December last year to ninth as of Thursday. Footage of the press conference was posted on the Spurs website, although the discussion about Mourinho was not included in the posted clip.
"The changing room I think has been fantastic," Son said, according to the Daily Mirror. "Obviously it is depending on the results. I am very sad if we lose. I am happy if we win. It is like everyone else."
Son was also asked about rumors that the players are unhappy with Mourinho's leadership.
"The mood went a little bit down when we had a couple of bad results but I think the changing room has not changed about these kind of things. Everyone is happy, everyone is having a laugh. Everyone is focused in every single game so what should I say? It is a bad rumor."
Son also discussed his partnership with Spurs captain Harry Kane.
"Harry is just so good and when he has the ball he's just looking around," Son said. "Scoring goals is what he can do, but his passing is just as good as this scoring. When he has the ball I know where to run. We've been working together for almost six years now and he knows what I like, so I think this relationship is very special, especially this season.
"We're the kind of guys who want to work harder than before and be better and better every day."
Spurs will be back in action in the Europa League against Wolfsberger today, or at 2:55 a.m. on Friday in Korea.
BY JIM BULLEY [email@example.com]
with the Korea JoongAng Daily
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It’s Sonam Kapoor‘s birthday today – HAPPY BIRTHDAY, SONAM! The fashionista turns 32 today and we’re sure her nearest and dearest ones are doing everything to make the birthday girl feel special. While we’re not sure of what her plans for the day are, her rumoured boyfriend Anand Ahuja definitely rang in her birthday in a rather special way.
He took her out for a game of mini golf (from what it looks like on his Instagram) and had the whole area customised with Sonam’s name lit up. How sweet. Check out his videos.
Aww. Happy Birthday, diva!
The post Videos: Anand Ahuja Sure Knows How To Make Sonam Kapoor Feel Special On Her Birthday is copyright of MissMalini.
from Bollywood – MissMalini https://www.missmalini.com/2017/06/09/videos-anand-ahuja-sure-knows-how-to-make-sonam-kapoor-feel-special-on-her-birthday/
Bollywood Entertainment Update

domain: entertainment


Members of Mumbai University's senate will write to vice-chancellor Rajan Welukar seeking an explanation on the state government handing over half of a four-acre plot meant for a central library for the university to a private developer to build luxury apartments.
“We want to know the exact terms of conditions on which the Kalina land was transferred to the state government. This land should be used for educational purposes only,” said Dilip Karande, a member of the senate, the highest governing body of the university.
HT had on Thursday reported that the government had entered into an agreement with Indiabulls Real Estate under which the developer would build the library on two acres and in return, be allowed to build residential apartments.
In return, be allowed to build residential apartments on the remaining two acres.
The University of Mumbai Academic Staff Association (UMASA) will also take up the issue in its general body meeting on Friday.
“We need to examine this carefully and take it forward from there,” said Neeraj Hatekar, executive committee member, UMASA.
University sources, who declined to be named saying they were not authorised to speak to the media, said the transfer documents clearly state that the land was transferred to the government only for the purpose of building a library.
Now, Indiabulls has a 42-month deadline to build a library on half the land.
“In a time when everyone is stressing on greater access to higher education, including in Maharashtra, it is appalling that the state is handing over land meant for educational purposes for luxury apartments,” said a senior university official.


Former captain Ricky Ponting and spinners Nathan Hauritz and Steve Smith are making good progress following surgery ahead of Australia's Test tour of Sri Lanka in August-September.
There has been a slight improvement in housing affordability in the March quarter, in line with stagnant house price growth during that time.
Willie Tonga has played down talk of his bravery after playing 63 minutes of the State of Origin opener with a busted shoulder.
Africa correspondent Ginny Stein
A painter faces jail for depicting massacres in Zimbabwe in which 20,000 people were killed.
Golf shooting star Jason Day is committed to playing the big Australian tournaments for the first time in his pro career and badly wants a national open title.
Former detainee Mohsen Soltany discusses his four years at Sydney's Villawood Detention Centre.
A man has been placed in an induced coma after being rammed by a cow at the Warrnambool saleyards, in south-west Victoria.
A Brisbane lawyer has lodged a High Court appeal on behalf of jailed former Bundaberg surgeon Jayant Patel.
A 27-year-old woman who helped dispose of a Newcastle man's body has been sentenced to a minimum of 12 months jail.
Stevedoring company Patrick says crippling industrial action at three of its ports will cost the company $8 million and set it back two months.
The Tasmanian Government has been accused of keeping secret a report detailing hundreds of assaults on prison guards at Hobart's Risdon Prison.
Gold Coast prop Matt White has apologised after being fined more than $1,700 for drink-driving.
Cricket Australia is proposing several modifications to boost the new-look domestic Twenty20 competition next summer.
Manly and Canterbury expect their respective State of Origin heavies to turn out for their clubs after Wednesday night's series opener.
The New South Wales Parliament will get to see the Coalition's major project planning arrangements with Chinese coal miner, Shenhua, following a call for papers in the Upper House.
Local councils in Tasmania believe their needs have been ignored in the forestry peace talks process.
Andrew Lindner takes us on a tour of his sock factory in Crookwell
Iconic actor Bill Hunter has been remembered with music and stories at a memorial service in Melbourne.
Andrew Lindner's family has been making woollen socks for nearly a century. It's one of the only businesses of its kind left in Australia.
Jharal Yow Yeh says he feels blessed after joining a select band of players who have celebrated their debuts for their NRL club, state and country with tries.
A change in attitude from Sydney's Lewis Johnston means the first-round pick from the 2008 AFL draft will make his debut on the weekend.
A Gold Coast driver who struck an elderly couple two years ago has been jailed for 18 months.
Carl Curtain: ABC Rural
Listen to Rob Cook chat about his trip as he rolls along.