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Bring Art History to Your Holidays! Looking for a fun way to tie art history into you holiday season, whether at home or in a school setting? Check out these beautifully created ornaments and greeting cards that have been inspired by master artists such as Monet, Van Gogh, Matisse, Chihuly, Pollock& Picasso.
for the entire month of november we will be baking, sewing& crafting up a storm, preparing handmade gifts for this holiday season. so dust off your sewing machine, & head on over to skip to my lou for some [. ] Easily design personalized Christmas ornaments for everyone on your list at Trim your tree with cherished memories of 2018 and beyond with custom Christmas ornaments for kids, couples, families, pets and more.
Christmas Art Christmas ornaments with pictures Xmas Christmas Fashion Christmas Ideas Christmas Snowflakes. Find this Pin and more on Christmas Inspired by Stacey. Buy Inspired Silver The Artist Circle Holiday Decoration Christmas Tree Ornament: Ornaments - Amazon. com FREE DELIVERY possible on eligible purchases Even though Christmas falls on the same day every year, it still manages to sneak up on me! Why is that? ? ! My best intentions are always to post some new Christmas art projects& ideas a month or two Artist inspired christmas ornaments of time, but then the busyness of the season just gets the best of me!
Christmas Crafts. Apple Cinnamon Ornaments. This reindeer Christmas tree ornament is fun (and easy to make) for a variety of ages.
Artist inspired christmas ornaments Andrea and Jantje. Famous Artists Inspired Christmas Ornaments and Greeting Card Ideas. Listly by Michelle East. Christmas Ornaments and Greeting Cards Inspired Famous. Limited Edition Artist Christmas Ornaments by various illustrators, painters, sculptors and photographers range from elegant to edgy for a truly artsy Xmas. Nov 15, 2014. Limited Edition Artist Christmas Ornaments by various illustrators, painters. Inspired by noir motifs and the dark underbelly found in the.
Jan 15, 2018. I've assembled a variety of artist-themed Christmas ornaments on this page, all of which you can order on-line from Amazon, eBay or other. Bizantine Art Inspired Christmas Ornaments Merry Christmas my dear friends! Well, that special time of the year full of love, joy and hope has arrived. It's a season of celebrations, tasting delicious traditional meals and beautifully decorating our houses. Personalized Artist Christmas Ornament - Canvas with Yellow Pink Blue Paint and Art Palette with Master Brush - Drawing Group Class Hobby Studio Designer Profession Teacher Mom - Free Customization by Ornaments by Elves Famous Artist Inspired Christmas Ornaments and Greeting Cards.
Tweet. Pin It. Famous Artists Inspired Christmas Ornaments and Greeting Card Ideas. Christmas Ornaments and Greeting Cards Inspired Famous Artists- Monet, Van Gogh, Matisse, Chihuly, Pollock& Picasso. 1. Unique, whimsical handcrafted, one-of-a-kind gift ideas include Ornaments. Campfire& Moose- Whimsical Special Occasion& Christmas Ornament.
Box of six Christmas ornaments with a design inspired by Gaudi. 13, 90 € In Stock In Stock Christmas Ornament. Faces Modern Art Christmas Ornament - Faces. Vintage Christmas decorations are our specialty! We carry both reproduction and true vintage decorations. Our selection of vintage& reproduction ornaments and. Mondrian Christmas Ornaments Inspired by Mondrian’s later work and the way that Wouter van Reek has used this to inspire the backgrounds of the illustrations in the book we’ve used these simple primary colours, straight lines and rectangles and squares to create a Christmas Decoration inspired by this famous Artist.
Looking for a unique gift for the artist in your life? Visit Personalized Ornaments For You for artsy and artist themed ornaments and keepsakes! Handmade clay decoration One of a kind by artist Lucy Deane. Inspired by Native American Indian symbols. your Christmas tree Native American Christmas Ornaments. Folk art-inspired ornaments, too, never need to be perfect in form and appearance.
The simplicity of their handcrafted look is part of the charm that can be enjoyed for generations to come, say. Jan and Christina collaborated in developing “The Art-Full Tree, ” a book featuring more than 30 Christmas ornaments that anyone can make — and all are inspired by the folk art collection.
Each project in “The Art-Full Tree” includes full-color photographs and detailed instructions. Awesome String Art Ornaments! Handmade by kids and inspired by the children's book - The Christmas Wish book by Lori Evert. Join us for a# KidMadeChristmas


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The Michigan Senate has approved a bill letting schools with too many snow days avoid having to schedule makeup days in June.
Schools instead could lengthen their days for the rest of the school year under legislation approved 34-1 on Thursday. The bill could win final passage in the House next week.
Supporters say the measure is needed because some districts in northern Michigan had more than the maximum six snow days, some as recently as April. They say families have already scheduled vacations and camps for kids after school ends.
Some schools are facing the prospect of extending the school year at least one more week if the legislation is not signed into law. Under the bill, schools would still have to meet the minimum 1,098 hours of instruction.

domain: news


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Originally Posted by stamp300
HAPPY BIRTHDAY! I'll have to make one tonight after work, or should I say after the kids Halloween bash at school.
Ooh, that sounds fun! It is the time of year! Can't wait to see what you come up with....after your Halloween fun! Thanks for the birthday wishes!

domain: entertainment


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Many developed men are sometimes asked what women Cookware need within a marriage. The answer varies, yet most Cookware women want to be treated with respect, and wish to feel that their particular men are interested in them, and get their passions. A true Hard anodized cookware wife would like nothing but the very best for her hubby, and will carry out their best to be the best they can become for their husband. If you are really considering marriage with an Cookware woman, after that this article will help you learn what women Hard anodized cookware need in a matrimony.
For starters, it is important that you esteem your Oriental wife. There exists a lot of false impression about how males treat the wives, in terms of marriage. You need to always be well intentioned to your Asian girlfriend. Just about every Asian female wants her man to treat her with respect, since it shows her that she’s most suitable. Your sweetheart wants her husband to discover her because desirable as is feasible.
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Finally, when you discover what females Asian need in a marital life, it is important to keep in mind that it is not really about you. You aren’t the only person http://nocomment.store/index.php/2020/11/16/where-to-find-ukrainian-ladies-marriage-videos/ who’s important inside your spouse’s life, and if he still adores afterward you that is more than likely true. Women are very intuitive and they pick up on the indicators that a gentleman gives these people. As a result, it is vital that you do not ever take the relationship with no consideration. Will not take it for granted even when you are with your wife.

domain: sociology


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Virgin of the Rosary of Guápulo, ca. 1680 | Peruvian (Cuzco) | Oil on canvas
Manuscript Leaf with Initial S, from a Gradual Date: second quarter 15th century Geography: Made in probably Mainz, Germany Culture: German Medium: Tempera, ink, and metal leaf on parchment Dimensions: 19 3/4 x 14 1/8 in. (50.1 x 35.9 cm)
james stirling, florey building axonometric better in colour?
Turnabout, Badessi, Piana & Pradella - Atlas of Places
Giovanni Bellini (Venice, circa 1430 - Venice, 1516) Congress of the Order of the Crescent
Big U; by Francesco Zorzi, 2014
Breviary printed in Venice by Nicolaus Jenson: 1478 Hunterian Bf.1.18 by University of Glasgow Library

domain: artistic


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laarman History, Family Crest & Coats of Arms
- Origins Available:
Early Origins of the laarman family
The surname laarman was first found in the Rhineland, where this family was a prominent contributor to the development of the district from ancient times. Always influential in social affairs, the name Laarmann became an integral part of that turbulent region as it forged alliances with other families within the region and the nation.
Important Dates for the laarman family
This web page shows only a small excerpt of our laarman research. Another 90 words (6 lines of text) are included under the topic Early laarman History in all our PDF Extended History products and printed products wherever possible.
laarman Spelling Variations
Spelling variations of this family name include: Laarmann, van der Laar, van Laer, von Lahr, Lahrbusch, Lahrmann, Larman, Laarman, Lehr, Lehrman, von Lehr, Laerman, Laermann, Laer, Lahr and many more.
Early Notables of the laarman family (pre 1700)
More information is included under the topic Early laarman Notables in all our PDF Extended History products and printed products wherever possible.
laarman migration to the United States
Some of the first settlers of this family name were:
laarman Settlers in United States in the 19th Century
- Geesje Laarman, who settled in New York in 1846
- Jan Laarman, who settled in Michigan in 1847

domain: library


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As an Amazon Associate I earn from qualifying purchases.
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Ntosh Gazi – Naledi ft DJ Tarico, Layla Melodious & Sam Kam MP3 Download
Our top pick off newly Ntosh Gazi released project, is the track that is titled Naledi. The track that encapsulates the awesome vocals from South African array of good music artists like DJ Tarico, Layla Melodious & Sam Kam. The Mzansi well renowned disc jockey has really put in more patience and efforts to seeing that this song came through with high tastes of good sounds.
Also, the South African now trending disc jockey DJ Tarico, is the main man that gives this collaboration more vital vibes. As he hop loudest with his beautiful hype on the song. Remember he grew from SA to being an international star after he featured Grammy Award Winning singer Burna Boy. When the Remix of Yabakuluku came through for the fans. It’s really a party vibe for everyone.
Without further ado, let’s come back to the song of the day “Naledi” which our owner of the song Ntosh Gazi features the array of South African music stars DJ Tarico, Layla Melodious & Sam Kam. At this junction, vibe along with this awesome tune and don’t forget to share your thoughts below:


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For nearly the entire game, Brian Hoyer bested Joe Flacco, Andrew Hawkins– not Steve or Torrey Smith -- was the most dangerous threat on the field and the Cleveland Browns outplayed the Baltimore Ravens.
But what the Browns found out in their 23-21 loss on Sunday at FirstEnergy Stadium, is that minor miscues in the fourth quarter can offset playing 50 minutes of superior football.
"I thought for the bulk of it the players played well enough to have a victory," said Browns coach Mike Pettine. "I put this one on me. We didn't coach well enough to win today."
Pettine's statement is bold and a noble one. His players quickly suggested in the locker room no loss should ever be squarely placed on the head coach.
"That doesn't make any sense," said cornerback Joe Haden when he was told about Pettine's comments. "He did a great job out there. We had a lot of chances to win, and there are a lot of things we could have done better, but we just didn't finish."
Because of the bye week's early arrival, the Browns will have two weeks to figure out which part of this loss was on coaching, and which part was on the players.
When the Browns gather Monday to review the film perhaps no player will be clinching his teeth in more irritation than Haden. The Pro Bowl cornerback did a terrific job most of the afternoon marking many members of the Ravens' receiving corps – one of the most underrated units in the AFC North.
With 1:28 left in the game, on a second-and-five from the Browns' 45-yard line, it appeared Haden was expecting some type of slant or out route from Steve Smith. Haden slowed down in his coverage, while Smith blew by him. The Ravens dialed up a go-route to catch the Browns off-guard, Flacco hit the veteran Smith in stride, the Ravens were in business at the 13-yard line and three plays later Justin Tucker booted the winning 32-yard field goal.
"We pride ourselves on going on the field, making plays and getting stops and I just didn't do that today," said Haden.
This loss wasn't just on Haden and the rebuffed secondary. It was a slow and team-wide unraveling that began in the fourth quarter -- quite the turn of events following Hoyer's ability to engineer three 80-yard touchdown drives in the first 45 minutes of the game.
With 10:51 left in the fourth quarter, the Browns' defense trotted off the field following a humongous fourth-and-one stop from Jabaal Sheard. It was one of the few times the defense was able to stuff the surprising Ravens rookie running back Lorenzo Taliaferro (18 carries, 91 yards, 1 touchdown).
All the offense needed to do was slowly move the ball down the field, pound in another touchdown from one of the rookie Baby Backs and walk into their bye week with a borderline stunning 2-1 record. It seemed like that prophecy was about to become the Browns' reality when Taylor Gabriel dove to catch a deep Hoyer pass 50 yards in the air, that got stuck in the swirling Cleveland winds. Gabriel raced to his feet and wound up with a 70-yard gain and the ball on the Ravens' 9-yard line.
Then, the pipes started leaking until they ultimately burst, again. Terrance West (12 carries, 36 yards) ran from side-to-side for a loss, Hoyer was sacked on second-down and then was penalized for throwing the ball over the line of scrimmage on third-down. Inexplicably, Billy Cundiff's ensuing field goal attempt was blocked off the edge from Baltimore.
"You can't blow opportunities like that," said Pettine. "We need to be more on point when we get opportunities like that to take advantage of them – not go backwards."
Blaming the Browns' offense is a tough accusatory proposition. For the first time since 1969, the team has opened the season with three straight games scoring 21-points or more. But in the pass/fail league that Pettine has clearly communicated to the Browns, Cleveland failed when it mattered most.
Hoyer's third-down pass right before the two minute warning was a touch behind Hawkins. It would be the last time the Cleveland offense would take the field.
"Really when it comes down to it, we made a lot of plays but we didn't make them when we really needed to," said Hoyer, who at one point completed 14 straight passes. "In this league, you have to do it when it's on the line. We did it last weekend; we didn't do it this week. As good as we felt the whole game, when it comes down to critical moments, we just have to make more plays."
Twelve penalties for 94 yards hurt, but none look sloppier than the two 12-men in the defensive huddle infractions in goal-to-go situations. The ball may have only been spotted a few yards closer because of the half-the-distance rule, but Baltimore used both penalties to score touchdowns.
Where was the miscommunication? How does it get cleaned up?
"We have to do better," said linebacker Karlos Dansby, who finished with five tackles. "We have to play technically sound and make better plays. That's the nuts and bolts of it right there."
With 2:35 left in the fourth quarter, Baltimore lined up to punt. It could've been the last time the Ravens touched the football. Punter Sam Koch blasted the football up in the air towards Travis Benjamin. Instead of fair catching the ball right near the 20-yard line, Benjamin let the ball bounce and eventually stop on the 7-yard line.
Why didn't Benjamin fair catch that ball? Did he have a mental lapse, or was the play just bad luck? The reversal in field postion made Spencer Lanning eventually punt from the end zone and helped the odds of Tucker's field goal to be of the chip-shot variety.
"I wasn't afraid at all," Benjamin said in the locker room. "I got up under the ball correctly and at the last minute, a gust of wind blew it and it went past my hand. I didn't want to go back and reach for the ball, so I just let it pass."
Earlier in the game, on a 39-yard trick pass play from Hoyer to Johnny Manziel – a brilliant call, by the way – West was flagged for an illegal shift.
Did the Browns get caught up overthinking their mistakes during a game, which led to even more?
Pettine and the veteran leaders will have 14 days to pinpoint the big areas of improvement before traveling to Tennessee to take on the Titans.
"I think it's important not to worry about what happened the previous drive or the previous play – it's important to just focus on the play that you're on," said Thomas following the loss. "[We] can't worry about something bad that happened the previous series – or something good, because when you get the momentum, you can't relax."

domain: sports


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“Everyone is my teacher. Some I seek. Some I subconsciously attract. Often I learn simply by observing others. Some may be completely unaware that I’m learning from them, yet I bow deeply in gratitude.” – Eric Allen
Life is funny, in that we often start in one place and end up in another — or visualize ourselves being somewhere other than we are. But I like those kinds of opportunities and surprises.
My desire in starting my own photography business was to photograph families. Posed, candid, whatever… if there was a family who liked my work and wanted to be in front of my lens, send them my way! So when my friend Sara asked me to take promotional photos for her new venture, Discovery Preschool and Family Center in Soquel, I was honored but also a little unsure that I would be able to deliver what she envisioned. It’s one thing to have a family trust that I can capture their heart and soul in a few photos and another to work in an enclosed space with walls and ceilings, utilizing my flash, taking images that will be used for business purposes and not necessarily hung on walls or tucked away in photo albums in families’ homes.
But that’s part of why I like these sort of challenges. I have to learn to trust that someone else sees quality and value in my work and believes that I can take photos that they will love. In this case, my friend trusted that my photos would be good promotional tools for her business. That’s a huge high-five to me. Beyond that, every opportunity I receive to take photos is a place of learning for me. I went into this preschool to photograph children and families in an educational setting, but I was getting a schooling, too.
The children were able to explore the main school room and play. My job was really to observe and photograph them utilizing the space. I see technical errors in some of these photos, or missed opportunities if I wasn’t able to get my settings right before a child ran off, but those are constants in my line of work. Children are wont to run and play, and that’s exactly what I love most about photographing children and families.
Discovery also has a family center, with classes and groups for families, including parenting support groups, classes like Tutus and Fairy Wings, and a Saturday kids camp.
The space is warm and inviting. bright and cheerful. Sara and her staff have done an amazing job designing the space and making it feel like a place many families can call home.
Ultimately, Discovery Preschool and Family Center is a home for learning. It is a community space where families can get to know one another, support each other, interact and have fun, with education at its backbone. For me, it has been a space to learn more about my craft, but I also plan to take my son to classes there, to grow together and always seek out new challenges, adventures and learning opportunities. I know this community of educators are paving the way for a thriving environment for hands-on learning.


"We wanted to remind people who might be working or visiting downtown that while the decision to give is entirely their choice, there is a better way to give," Downtown Dayton Partnership President Sandra Gudorf said of Real Change in a press release during the inaugural year. "We are fortunate to have a wide supplement to our social services network, and we wanted to make sure we promoted the good work these groups are doing."
>>RELATED: City officials say there's a better way to give to those in need (Dec. 18, 2017)
In addition to St. Vincent de Paul and the Downtown Dayton Partnership, the United Way of Greater Dayton, City of Dayton, Montgomery County Health and Human Services Department, Homefull, Goodwill Easter Seals and other local nonprofits are involved with the campaign.
Each year, a different nonprofit will be selected to receive the money donated.
>> 6 things Dayton is doing to address the explosion of panhandlers — and how you can help
"What people might not realize is you can give a dollar to someone standing with a sign at the intersection, but that same dollar can be stretched farther when it's donated to a local nonprofit or social service agency," said Tracy Sibbing, vice president of community impact at United Way, said as part of that press release. "These organizations have built extensive networks and can leverage donations to maximize the number of people who can receive benefits. Real Change Dayton will help these nonprofits continue their great work and get people back on their feet. Our ultimate goal is to help those in need to change their futures for the better."
>> RELATED: Beggars brace as city says ‘it’s OK to say no’ to them


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Looking at the experience of the personal injury legal expert is fundamental as well as you make your choice. There is so much skill that is required with the goal that the expert can be try to get the customer the compensation that they need. Choosing personal injury legal expert that has expertise in taking care of these cases, can guarantee you of a great result from your case. The legal expert will have an idea on what he needs to do to get a strong defense for your case on the off chance that he is experienced to deal with these cases. The legal expert that you choose to settle on must be a person that has offered these services for a long time.
After getting all the fundamental data, guarantee that you call the personal injury lawyer. The advantage of making this call is so you can learn more about the lawyer. When you call them, it is critical to make numerous inquiries about them. You can know about you need to work with the legal expert or not founded on how he answers you.

domain: law


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12-song project ‘created for a generation searching for purpose, identity & acceptance’
“Growing Pains,” the debut album from Elevation Rhythm, is out today. Listen here.
As an essential part of Elevation Church based in Charlotte, North Carolina, the group sets the musical compass for a younger generation of worshipers. With youth and young adults at the forefront of its mission, Elevation Rhythm’s sonic backdrop is intentional to keep up with the changing times, which is why the group experiments with a variety of bold sounds and textures. Incorporating elements of pop, rock, worship and hip-hop, each of the 12 songs found on “Growing Pains” offers the youthful energy found in its diversity.
“I think, sonically, Rhythm is always going to be different,” producer Josh Holiday said. “Two years from now, Rhythm won’t sound like it sounds now because the sounds of the next generation are always evolving.”
While the group has previously released a handful of singles, such as “Quiet” and “Never Walk Away,” “Growing Pains” is a cohesive introduction of the group to the world.
“This album feels like more of an overflow,” Holiday said. “We had more than enough songs. More songs ended up on the floor than they did on the album. We have a lot that we really want to say.”
Most of all, their message is timely as they are speaking to a generation emerging from a global pandemic and feeling more confused and lonely than ever before.
“At the forefront of our minds is writing for youth and young adults in our church and trying to give language to things they’re going through,” Elevation Rhythm member Davide Mutendji said.
Every song on “Growing Pains” has already been shared at the church's monthly youth gathering, “Rhythm Nights,” and some of them have been led for more than a year. Overall, the album is intended for a generation searching for purpose, identity and acceptance.
“We don’t try to target Sunday mornings or Wednesday nights,” Holiday said. “We also target Monday, Tuesday, Thursday, Friday and Saturday. We want to make music for every day of the week.”
The group will share some of these songs live when they join Elevation Worship along with Pastor Steven Furtick on the spring arena tour “Elevation Nights.” Kicking off April 26 in Chicago, they will bring the experience of Elevation Church to cities around the U.S. The tour will wrap in Boston on May 5. Tickets are on sale now. For more information, visit ElevationNights.com.
Elevation Rhythm (Images courtesy of Merge PR)


text: Coronary artery disease (CAD) describes a heart disease in which the blood vessels of the heart, the coronary arteries, become calcified and narrowed. Thus, the blood's path to supply the heart is blocked by narrowing. In the worst case, coronary heart disease (CHD) can thus trigger heart attacks or even lead to cardiac death. But what are the symptoms of coronary heart disease? Learn more here.

domain: biology


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The World Health Organization (WHO) has set out a plan that it hopes will help reduce the burden of foodborne disease.
WHO officially launched its food safety strategy for 2022 to 2030 this week and pledged support for countries to implement it. The agency was asked to update a 2002 document in 2020.
Every year, one in 10 people globally fall ill due to foodborne diseases and 420,000 die. Contaminated food can cause over 200 diseases, and the public health burden is comparable to malaria or HIV AIDS. Children under 5 years old are at higher risk, as one in six deaths from diarrhea are caused by unsafe food.
The plan sets concrete targets on the burden of foodborne illness with a 40 percent reduction by 2030 in the global average of foodborne diarrheal diseases incidence estimated per 100,000 population from a 2010 baseline of 4,154 cases per 100,000 population.
WHO said aiming for such a reduction was a “good balance between feasibility and aspiration”.
Two other indicators measure national capacities to detect and manage food safety incidents.
The strategy has been developed to support countries in their efforts to prioritize, plan, implement, monitor and evaluate actions aimed at reducing the burden of foodborne diseases by strengthening food safety systems.
An update was requested due to more environmental challenges, new digital technology, demographic changes and changing expectations around food. However, systems in many countries face challenges and need significant improvements in regulatory infrastructure, enforcement and surveillance, food inspection and laboratory capacity and capability, coordination to prevent and manage events, and food safety education and training.
Five priorities include strengthening national food control systems, improving the use of food chain information, scientific evidence and risk assessment in making risk management decisions and promoting food safety as an essential component in domestic, regional and international trade.
Progress will be tracked with the first report to the World Health Assembly in 2024 and every two years until 2030. To judge implementation of the strategy, in 2025 and 2030 updated numbers will be published on foodborne diarrheal disease estimated incidence per 100,000 population.
Other ongoing work
Almost 100 comments were submitted while the strategy was in draft format from governments or ministries, the private sector, NGOs and academic institutions and other United Nations agencies.
A baseline survey with the International Finance Corporation (IFC), part of the World Bank Group, to adapt an existing tool to assess food safety policies and measure implementation of the strategy, will be available in early 2023.
Discussions are also ongoing about reviving the Global Foodborne Infections Network (GFN), which was launched in 2000, to help strengthen laboratory-based foodborne disease surveillance.
A Food and Agriculture Organization (FAO) strategy on food safety from 2022 to 2031 is also set to be published later this year, revising a 2014 version.
An update to the global burden estimates for foodborne diseases, first published in 2015, will be completed in 2025 by the Foodborne Disease Burden Epidemiology Reference Group (FERG).
(To sign up for a free subscription to Food Safety News, click here.)

domain: medical


Helping to create Jobs and Affordable Housing.
Remedy for Humanity projects to build out affordable housing within that community or help families with housing.
Humanitarian Project Funding Focus Areas…
The TRFH is focused on addressing the most acute needs in areas that have the potential to be solved by innovation in one or more of the following five areas:
1. Safe Water and Sanitation
Bold ideas, technologies, processes and approaches that enable rapid provision of safe water and safe disposal of waste and sewage in the most vulnerable households and/or enable implementers to rapidly scale up programs.
Compelling ideas to generate energy, particularly alternative energy solutions that are possible to set up and maintain in special situations, and that power lifesaving and life-improving services such as health, information, water and sanitation, and education.
3. Life-Saving Information
Innovative ways to improve access to information and data to increase the impact of humanitarian assistance at the local level as well as enable more effective connections between affected populations and humanitarian actors.
4. Health Products and Services
New approaches to healthcare that enable one of the following services:
Support non-experts to provide quality care;
Empower skilled staff who choose to work internationally;
Allow faster and cheaper distribution of quality health supplies in mission fields;
Enable affected communities to manufacture or reuse high quality supplies.
5. Affordable Housing, making housing accessible to everyone by build housing units to serve lower income populations. Proposed Solution: Provide project developers with humanitarian funding that create small subdivisions fully self-contained with income producing farms within the communities.
A TRFH project director for each project will be assigned.
BSIX Odyssey California /TRFH project director, Mike Carpenter
Nevada's Gateway /TRFH project director, Gary Anderson
Idaho Agriculture, Energy and Water /TRFH project director, Mike Carpenter
Blue Water Aquaculture /TRFH project director, Gary Kean
Black Oak Farms /TRFH project director, Gary Kean
Blue Water Bay /TRFH project director, Gary Kean
URBAN WEST ECONOMIC DEVELOPMENT /TRFH project director, Gary Anderson/dp
Lupins, Plant Proteins/Shasta Farms /TRFH project director, Lee Stortz/sc
Agriburbia / TRFH project director, Richard Jackson
Defytime Fiji Public Benefit Trust /TRFH project director, Don Hargreaves
Philippines - Global Sanitation /TRFH project director, Tom Sawyer
Philippines - Affordable Housing / TRFH project director, Donna Costa
Green World Energy /TRFH project director, Gary Anderson
Symbiotic Plant Farms /TRFH project director, Clark Smith
Tafoya Medical Center /TRFH project director, Gary Anderson
G7G railway /TRFH project director, Randy Ziesenis


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Club Smith are a four piece band based in Leeds, UK. They released two singles during 2011 and released album "Appetite for Chivalry" on 12/11/2012, followed by singles "Beautiful & Useless" and "The Green Room" with mixes and additional production by Dave Bascombe and Lance Thomas respectively.
|1||Play on youtube||Lament||3,715 listeners|
|2||Play on youtube||No Friend of Mine||1,268 listeners|
|3||Play on youtube||Beautiful & Useless||1,016 listeners|
|6||Causing Doubt||685 listeners|
|7||Young Defeatists||492 listeners|
|8||The Green Room||400 listeners|
|9||Play on youtube||Call to Harm||302 listeners|


Oct 17, 2005 | Recent product withdrawals requested by the FDA and ballooning R&D spending despite disappointing drug pipelines have placed tremendous pressure on pharmaceutical manufacturers. To respond to safety issues, drug developers now require a greater number of tests earlier in the development process that can predict drug-like characteristics of lead compounds and that can identify appropriate pharmacokinetic and toxicity profiles.
The genomic era of drug discovery ushered in a style of research characterized by high-throughput science — screen thousands of drug targets against a vast array of chemical compounds, with the hopes that eventually a blockbuster would fall out — and the faster the better. However, the blockbuster model is being complemented by an approach designed towards identifying niche drugs for smaller patient populations.
In response to these changes, drug screening labs are placing higher value on the quality of experimental data and the insights that such data can provide and are focusing less on simply increasing the throughput of screening activities. The mantra has moved from more information to better information. Drug screening reagent and platform providers hope to address this need with products that save users time and therefore money by providing more usable and reliable information with less effort.
A case in point can be found with Eksigent Technologies. Eksigent, founded in 2000, provides microscale liquid pumping and flow control devices for liquid chromatography (LC) applications. They have targeted the LC market, as HPLC is the most widely used analytical instrument in the biomedical sciences, used by all pharmaceutical and biotechnology companies in both drug discovery and analysis of drug metabolism in clinical trials. HPLC and LC are often coupled with mass spectrometric analysis, which can identify compounds from drug metabolites to large proteins and complexes.
Eksigent’s Microfluidic Flow Control pump technology eliminates the flow splitters found in traditional HPLC instruments. The aim is to provide researchers the ability to immediately adjust flow rates for more accurate, consistent, and precise analyses. The technology is based on microfabricated systems created by lithographic techniques and uses continuous feedback to an electronically controlled pressure source to maintain precise nanoscale flow rates as low as 20 nL/min without flow splitting. New drivers can be integrated with Thermo Electron’s Xcalibur and Applied Biosystems/MDS Sciex’s Analyst 1.4.1 mass spectrometer platforms. Users can operate the ExpressLC-100 and the mass spectrometer as one integrated system.
Micro-Tech Scientific launched a competitive product in 2004 called the X’TremeSimple NanoHPLC system that offers precise low-volume flow control without the use of splitters. The system, compatible with the Xcalibur and Analyst platforms, can be used for nano-LC-MS, capillary-LC-MS, proteomics drug discovery, protein drug quality control, and automated microtiter plate sample preparation for MALDI-MS. Micro-Tech also offers the Ultra-Plus, a microflow product comparable to the Eksigent ExpressLC system.
Eksigent and Micro-Tech compete with much more established players in the LC pump market such as Dionex, Waters, and Agilent. The ExpressLC and Ultra-Plus systems are competing with Agilent’s 1100 Series HPLC and Capillary LC systems. The 1100 Series capillary pump incorporates an electronic flow control and can be combined with Agilent’s mass spectrometry products for analysis of tiny samples and extremely low analyte concentrations inherent to many proteomic applications. Comparable systems offered by Waters are the Acquity UPLC and nanoAcquity UPLC. The nanoAcquity UPLC system is optimized for high-resolution separations at precise nanoflow rates and is appropriate for biomarker discovery and proteomic applications. It can be combined with Waters’ Micromass Q-Tof Premier for multiplexed qualitative and quantitative protein expression profiling.
All of these systems are designed to save the user time while at the same time offering higher precision and sensitivity that are key to better comparative proteomic data coming out of LC-MS applications as well as more traditional clinical and diagnostic analyses performed routinely by pharmaceutical manufacturers.
E-mail Robert M. Frederickson: email@example.com.


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Thank you for writing to us.
Most likely the "one-sided headache" that you are having is as a result of blockage of your nose resulting in blockage of your sinuses
and leading to the type of headache that you are having.
Sinuses are air filled spaces that are present in the skull and all of them drain into the back of the nose (not visible to us).
When one has a cold
the nose gets congested and the sinuses have the tendency to get blocked.
There is a sinus in the head that is called as the frontal sinus.
When the sinuses get blocked they can cause one to have headache on the side of the head where the sinus is blocked.
I would strongly recommend that you should contact an ENT doctor for further evaluation of your condition and possibly do further tests like an x-ray of the sinuses or a CAT scan of the sinuses to be sure.
I would also like that the ENT doctor should examine your nose to see if you do, or do not, have a deviated nasal septum
which can also cause such kind of a problem.


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Glen Morgan and James Wong have finalized deals to return for Fox's 6-episode revival of The X-Files, alongside creator Chris Carter.
Mitch Pileggi confirmed on his Twitter account today that he will return as Walter Skinner in Fox's 6-episode X-Files event series.
David Duchovny reveals on Late Show with David Letterman that William B. Davis and Mitch Pileggi will return for the new X-Files event series.
The X-Files creator Chris Carter reveals he has 'ideas' for everyone in the original cast to come back for this new limited series.
David Duchovny and Gillian Anderson have signed on to return as Fox Mulder and Dana Scully for a six-episode X-Files event series.
Fox is nearing a two-season order for an X-Files revival which would bring back stars David Duchovny and Gillian Anderson.
X-Files star David Duchovny says he's ready to rejoin co-star Gillian Anderson, but can't do a full season.
The actor speaks out about possibility of the third installment of the sci-fi series, plus what went wrong with the second movie.
The actor who portrayed Fox Mulder reveals he would be on board for a third installment.
We have all the details on this new two-disc collection of episodes.
Mulder and Scully themselves sit down behind-the-scenes at Wondercon to talk about a brand new case.
The director and producer sit down behind-the-scenes at Wondercon to spill the beans on Mulder and Scully.
David Duchovny and Amanda Peet film a scene in Vancouver.
David Duchovny and Gillian Anderson will return.

domain: celebrity


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LUDHIANA: Actress Jimmy Shergill has been booked by Ludhiana Police for violating the COVID-19 protocols.
SI Maninder Kaur said that Jimmy Shergill’s team had been shooting a Punjabi film at Arya School for the last three days. Because of this, the school building was transformed into a set of session courts.
On Monday, police was informed that no social distancing is being followed there and no one was wearing a mask on their face. Due to this, the police team led by ACP Central Variyam Singh charged them with two fines.
Despite this, the team again violated the rules.
Later on, Tuesday, police received information that the shooting is going on during the night curfew hours and close to 150 people were present on the set. When the police raided again, the allegations were found correct. Police arrested 4 people, including Jimmy Shergill, with immediate effect. Of these, the remaining 3 have been identified as Ishwar Niwas, resident of Park Plaza, Varsova Panch Marg, Mumbai, Akash Deep Singh, resident of Sioda Chak, and Mandeep, resident of Madhuban Home in Zirakpur. They have been arrested for violating the government order and a case has been filed under the 3 Pandemic Act and other sections.


The 2019 Lincoln Town Car is going to be a return of the elegant sedan. Numerous fans, experts, and rivals are waiting to see exactly what does it bring. And given that this is an elite car, there will be a great deal of everything. It is difficult to contend the Continental sedan from the very same company at first place. Furthermore, Cadillac is preparing brand-new XTS with numerous upgrades, so brand-new Town Car could be the ideal response to any dangers. We can expect nothing however sophistication, convenience, and pleasure from a brand-new car, and designers in Lincoln are specialist to provide these.
2019 Lincoln Town Car Platform
After eight years, the elegant car is preparing for its return. It is not going to share lots of parts with its predecessor from 2011, so it will be fascinating to see all details on 2019 Lincoln Town Car. The advancement of it might begin with Continental. These 2 vehicles will share a platform, but the sedan is going to be quite various. Taillights will cross the trunk. There are couple of alternatives for grille up front, however designers have not decided which to location. Interior is classy and abundant. Premium products and a lot of details will leave nobody apathetic. The new dashboard will reveal all details a motorist needs.
2019 Lincoln Town Car Specs
To have a complete elegant car, the company needs to put a good engine in it. Because of that, brand-new 2019 Lincoln Town Car comes with 3.5-l EcoBoost drivetrain. It is going to be ready to crunch 350 horse power, which suffices for a full-size sedan. Power takes a trip through a 6-pace automated transmission, which distributes it to all wheels. Option for the very first system is a 2.7-l V-6. The turbocharging system can make this mill produce 360 hp and 380 lb-ft of torque. It uses the very same transmission to spread out the energy. Top speed of the Town Car will be around 130 miles per hour.
2019 Lincoln Town Car Release Date
The 2019 Lincoln Town Car is being available in the last quarter of 2018. The company is still peaceful on any details, but leaking sources say that we can expect the best quickly. However, it is not going to be a production model, but still, we will find out more information about the luxurious sedan.


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Last year's Champions League finalists meet again this Saturday as Liverpool host Tottenham at Anfield Road. Teams are facing different moments so far in the competition as Liverpool will try to extend his home record of 44 game without a defeat while Tottenham will try to win an away game for the first time in this season's Premier League.
Klopp's team started the Premier League flying, winning the first 8 matches in the competition. The Reds lost the first points in the competition last weekend at Old Trafford, with a 1-1 draw against rivals Manchester United. Anfield is an absolute fortress of Liverpool, as the club don't loose a Premier League home game since April 23rd 2017, when Sam Allardyce's Crystal Palace defeated Liverpool 2-1. In 4 matches so far this season for the Premier League, Liverpool won all of them, averaging 3 goals per game. Trent Alexander Arnold and Andrew Robertson are doubtful for Sunday's match.
Alisson; Milner, Matip, Van Dijk, Robertson; Wijnaldum, Fabinho, Henderson; Salah, Mane, Firmino
Tottenham has been facing hard times in these first months of the season. Already took a huge 7-2 blow at home against Bayern Munich for the Champions League and in the Premier League, things are even worse. Pochettino's side doesn't get an away victory since January and are winless in the last 2 matches. For Sunday, Lloris will not be fit to play as well as Ryan Sessegnon.
Gazzaniga, Aurier, Alderweireld, Vertonghen, Davies; Sissoko, Ndombele, Dele Alli, Lucas, Heung-Min Son, Kane
Despite huge doubts regarding the availability of Robertson and Trent Alexander Arnold, Liverpool are huge favourites and should get the victory.
2020 Copyrights © All Rights Reserved.

domain: game


text:
Intracerebral microdialysis was utilized to investigate the effect of P-glycoprotein (a drug efflux transporter) induction at the mouse blood-brain barrier (BBB) on brain extracellular fluid concentrations of quinidine, an established substrate of P-glycoprotein. Induction was achieved by treating male CD-1 mice for 3 days with 5 mg/kg/day dexamethasone (DEX), a ligand of the nuclear receptor, pregnane X receptor, and a P-glycoprotein inducer. Tandem liquid chromatography mass spectrometric method was used to quantify analytes in dialysate, blood and plasma. P-glycoprotein, pregnane X receptor and Cyp3a11 (metabolizing enzyme for quinidine) protein expression in capillaries and brain homogenates was measured by immunoblot analysis. Following quinidine i.v. administration, the average ratio of unbound quinidine concentrations in brain extracellular fluid (determined from dialysate samples) to plasma at steady state (375-495 min) or Kp, uu, ECF /Plasma in the DEX-treated animals was 2.5-fold lower compared with vehicle-treated animals. In DEX-treated animals, P-glycoprotein expression in brain capillaries was 1.5-fold higher compared with vehicle-treated animals while Cyp3a11 expression in brain capillaries was not significantly different between the two groups. These data demonstrate that P-gp induction mediated by DEX at the BBB can significantly reduce quinidine brain extracellular fluid concentrations by decreasing its brain permeability and further suggest that drug-drug interactions as a result of P-gp induction at the BBB are possible. Applying microdialysis, distribution of quinidine, a P-gp substrate, in mouse brain extracellular fluid (ECF) was investigated following ligand-mediated P-glycoprotein (P-gp) induction at the blood-brain barrier (BBB). We demonstrated that a PXR agonist (dexamethasone) significantly up-regulated P-gp in brain capillaries and reduced quinidine brain ECF concentrations. Our data suggest that drug-drug interactions as a result of P-gp induction at the BBB are possible.
Keywords: P-glycoprotein; blood-brain barrier; induction; microdialysis; pregnane X receptor; quinidine.
© 2013 International Society for Neurochemistry.


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The long-term future for coal in power generation, at least in the developed world, will depend on technology that is able to meet ever tighter environmental constraints at a price which is competitive with other forms of generation.
The most thermally efficient and least environmentally damaging of the cleaner technologies is the integrated gasifier and combined cycle (IGCC) system, which converts coal into a clean gas – a mixture of hydrogen, carbon monoxide and, in some cases, methane – and feeds it into a turbine.
Unfortunately IGCC is also the most expensive option, with an installed cost of up to 5p/kWhm – double that of gas-fired stations and significantly higher than that of conventional combustion coal plants. The construction of IGCC plants will depend, therefore, either on subsidy or a significant reduction in costs: in the near term probably both.
Air Products and Chemicals of the US may have found an answer to the cost issue with a new technology for producing methanol. It believes that fitting this system, which produces methanol at twice the rate of conventional methods, on the back end of the gasifier units on an IGCC plant can cut the capital cost by 25%.
The technology achieves this saving by reducing the number of gasifiers the IGCC plant needs – provided the full capacity of the power station is not required for baseload running. Dennis Brown, the research and development manager for Air Products Europe, says that on a 450MW IGCC plant the number of gasifiers could be reduced from four to three.
This enables the operator to make full use of the gasifers, which account for 50-60% of the cost of an IGCC and become prohibitively expensive under part-time operation. When power is not required, they can be switched to methanol production. This provides the additional fuel to meet full power output at times of peak demand. ‘You would get the extra electrical capacity by taking methanol out of your store,’ says Brown.
Air Products’ liquid phase methanol process passes the hydrogen and carbon monoxide produced by the gasifier through fine particles of a conventional methanol-producing catalyst suspended in an inert fluid rather than through a bed of dry catalyst pellets. The technology has completed 700 hours of stable operation at Eastern Chemical Company’s coal gasification facility in Kingsport, Tennessee, where it produced 260 tonnes of methanol a day.
Brown says, however, that potential clients have been more interested in boosting the economics of IGCC plants through exploiting the additional methanol production than in saving on the cost of a gasifier. While the methanol produced by the process would need further dewatering to achieve the grading for a chemical feedstock, it is a viable product for the power generation and fuel additive markets – its unit cost of about 9 cents a litre is 20% less than the current market price.
Brown accepts these additional benefits will not make an IGCC unit competitive with a combined-cycle gas-turbine (CCGT) plant where there is an adequate supply of natural gas. But he thinks a 500MW unit could compete with traditional coal-fired technology and could offer big opportunities in the countries that will build thousands of gigawatts of coal-fired plant over the next 10 years, such as China and India.
National Power, the UK generator which has joined RJB Mining’s study into the feasibility of building a 400MW IGCC plant at Kellingley colliery in West Yorkshire, is more cautious. ‘In our view it makes a marginal change, though it’s certainly not something to ignore,’ says Richard Hotchkiss, research engineer at National Power.
According to John Griffiths, technology development manager at energy consultant Jacobs Engineering, the difficulty is to secure a long-term purchase contract for the methanol that will allow the plant operator to keep the gasifiers in continuous operation. ‘If you can’t run them flat out all the time, you’re going to incur large capital charges.’
Jacobs was part of a consortium that designed a 500MW unit to produce 500-1,000 tonnes of methanol a day in the daylight hours and 1,500 tonnes overnight. But the scheme foundered on the problem of finding a long-term offtake contract for the methanol – the volatility of the crude product’s price makes this extremely difficult. ‘You can’t find a chemical market to match the electricity you’re making,’ says Griffiths.


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SOLD, PLEASE VISIT US AGAIN!
A fine pair of Boucheron cufflinks worked in 18K yellow gold, the oval faces centered with richly-colored citrines. The gold surfaces are worked in a wavy ridged pattern, and the citrines are ingenuously fantasy-cut in the same style. The quality of workmanship is evidenced in the manner in which the carving of the citrines matches exactly to the ridges of the gold settings where the two meet. THe backs are hinged. The connectors are fully marked with Boucheron's retailer and marker's mark, the 18K gold standard and serial numbers.
Origin: France. Dimensions: front faces, 1/2" x 5/8". Weight: 16.7 grams. Approximate Total Gemstone Weight: 4.96 cts.


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pearls on wedding cakes
Things are still all a bloom around here thanks to a nice combination of April showers and warm, sunny days.
Which means I’m still looking for wedding cakes adorned with fresh flowers because they’re absolutely perfect for spring weddings.
This four-tier square wedding cake is elegant and simple and has a fresh feel about it.
The square tiers give the cake a modern feel, while the pearl icing embellishments add just the right amount of elegance.
And you can’t go wrong with fresh cattleyas for a floral addition.
Of course if you aren’t a fan of that flower you can always adorn your cake with a flower that matches your bouquet – giving your wedding cake an extra personal touch.
You can find this spring floral wedding cake here.
I’ve been writing a lot about the use of fresh flowers on wedding cakes and how much I love the trend.
Heck I even used fresh Black Magic Roses and greenery on my own wedding cake more than a decade ago.
Fresh flowers just never go out of style (in my humble opinion).
But, instead of using the whole flower, consider for a moment using just the petals from those fresh flowers – just like this cake. Read More
There are gorgeous, take-your-breath-away wedding cakes.
And then there’s today’s wedding cake which goes beyond leaving one breathless.
This cake is downright stunning.
The four-tier “novelty cushion wedding cake” is another amazing creation from our friends at Hockleys Cakes over in the United Kingdom.
The cake’s intricate and delicate pattern was based on the bride’s wedding dress Read More
As we’re heading into the week of celebrating all things love and Valentine’s Day, I wanted to share a cake with you that was so romantic it would make you swoon on the spot.
I’m pretty sure this is the cake.
This gorgeous four-tier creation is from Hockleys Cakes in the United Kingdom and they call it the “Blenheim Cake.”
This cake is all about romance and flowers and love, and I adore everything about it.
I love the square tiers on this cake – I’m a big fan of non-traditional shapes when it comes to wedding cakes. (This should come as no surprise, since my wedding cake featured eight heart-shaped tiers!) I think the square tiers give it a nice, modern contemporary feel.
The gorgeous and simple white icing with the pearls around each tier give this cake a dramatic and modern look.
But what I love most is the cascade of flowers down the side of the cake. The bride wanted the flowers to replicate her bouquet – which is a genius idea in my book! Hockleys created these flowers with hand crafted white, pink, and violet sugar roses and other dainty buds.
It’s incredibly romantic, don’t you think?
A big thanks to Hockleys Cakes for sharing this creation with us!
Photo courtesy of Hockleys Cakes.


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5 000 Kya Sands protesters set to hand over memo
Lauren Hess, News24
Johannesburg - Protesters were set to hand over a memorandum to officials on Monday following action where stones were thrown at cars and the police fired rubber bullets.
Both Johannesburg Metro Police (JMP) and South African Police Service (Saps) spokespersons confirmed the number of protesters swelled from about 200 early in the morning to about 5 000.
JMP department spokesperson Wayne Minnaar said motorists should still avoid the area around Malibongwe and Riverbend roads as there were rocks and other debris in the street.
“It’s not safe,” he said.
However, SAPS spokesperson Warrant Officer Balan Muthan said “the situation is calm” and “the roads are open”.
He said the protest was over a lack of housing.
Earlier on Monday morning, police fired rubber bullets and teargas at protesters.


text: The aim of this work was to give an evidence of the likely presence of interstitial cells in the canine lower urinary tract and to study their possible interactions with the musculature and the intramural innervation. irrespective of doggie sex. Cells with a similar localization were also PAS- and NADPH-diaphorase-positive. A contact between c-kit immunofluorescent cells and intramural innervation was exhibited, too. The functions of interstitial cells might include regulation of easy muscle activity of the bladder detrusor, integrating neuronal signals during urine storage and voiding. 1. Introduction The two main and correlate functions of the organs belonging to the lower urinary tract are the storage and periodic elimination of urine, that are fundamentally mediated by contraction from the muscular level and are governed with the somatic, sympathetic, and parasympathetic innervations, working synergically. Higher purchase modulation is in the nervous centers from the cerebral cortex, the cerebellum, and pons. Lately, many investigators have got suggested a network of cells triggering spontaneous contractions and myogenic gradual influx activity of the muscular wall structure in the urinary system of several mammalian types may can be found [1C5]. That is a topical ointment and current analysis region in useful urology, with feasible interesting rebounds on different pathologies . In the intestinal muscular level, the current presence of a harmonized activity essential for motion is certainly well is certainly and known controlled, in the individual  aswell as in pet types [8, 9] like the doggie , by the elaborate network from the so-called interstitial cells of Cajal (ICCs). In analogy Rabbit polyclonal to Vitamin K-dependent protein S with this functional program, many authors have got invoked an ICC-like program in the urinary system, coordinating the urinary peristalsis . An identical network of cells continues to be referred to as located under the urothelium in guinea-pigs strategically, and human beings [11C14], or on the known degree of the muscular level aswell, in rabbits, guinea-pigs and individual CB-7598 tyrosianse inhibitor [4, 15C17]. The existence was defined by Some writers of many populations of ICC-like cells, either located below the urothelium, in the lamina propria area, and through the entire detrusor [18, 19], producing cable connections with intramural nerves and connected with simple muscles cells carefully, in the detrusor. No reviews exist of the current presence of these cells in the low urinary system of your dog. Nevertheless, you’ll be able to conceive that abnormalities of this intrinsic program of motility control in your dog urinary tract might be at the basis of a variety of important urological diseases, such as the urethral incompetence mechanism, an acquired condition thought to be a consequence of a dysfunction in the musculature innervation . Unequivocal methods usually utilized for the demonstration of ICC are electron microscopy and a growing number of markers relevant to bright field and fluorescence microscopy . C-kit is definitely a transmembrane, tyrosine kinase growth element receptor indicated on fetal and adult cells, including the interstitial cells of Cajal of the gut. Also useful, although not definitive as only tests, are the histochemical reactions for diaphorases , and Periodic acid-Shiff (PAS) reactivity due to the high glycogen content material in ICC . Following our desire for the scholarly study of innervation of the lower urinary system in your dog CB-7598 tyrosianse inhibitor , this work is normally targeted at demonstrating the most likely existence of interstitial cells (ICs) in the canine lower urinary system. Over-mentioned tools had been utilized for this function, alongside the general neuronal marker proteins CB-7598 tyrosianse inhibitor gene item (PGP) 9.5, that was previously employed with desire to to tag nerve fibres with regards to IC cells . 2. Methods and Materials 2.1. Pets Samples were gathered at the Section of Veterinary Clinical Research from the Faculty of Veterinary Medication of Milan from adult canines of both sexes (3 men and 3 females), that have been euthanized after diagnoses excluding urinary pathologies (generally trauma). Body organ sampling was performed after approval of your dog owners. It had been verified which the organs of the low urinary tract had been healthy. Many fragments were attained within ten minutes of euthanasia in the bladder apex, body, and throat, and in the urethra, proximal towards the bladder neck. The male urethra CB-7598 tyrosianse inhibitor was collected at the level of preprostatic part. Fragments of healthy small intestine were collected as well, to be used as positive settings. 2.2. Cells Processing Cells fragments were immersed in 4% paraformaldehyde in 0.01?M phosphate-buffered saline (PBS) pH 7.4 for 24?h fixation at 4C. Samples were either (i) dehydrated inside a graded series of ethanol, cleared in xylene and paraffin inlayed, or (ii) cryoprotected over night by infiltration having a 20% sucrose answer in PBS at 4C, then snap freezing in liquid nitrogen-cooled isopenthane, using OCT (Tissue-Tek, CB-7598 tyrosianse inhibitor BDH, UK) as an embedding medium. Either deparaffinized microtome sections (4C6?was hard, actually in the intestinal wall which was used mainly because positive control for immunoreactions, owing to their paucity, small dimensions, and sparse distribution in the smooth muscle layer.


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Adam Torres and David Hankins discuss Powers Squared comic books
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Apply to be a guest on our podcast here.
Who doesn’t like a great comic book? In this episode, Adam Torres and David Hankins, Owner, Co-Creator and writer at Powers Squared, talk about 2020 plans and the upcoming comic book signing.
About Powers Squared Comic Book
Powers Squared is a New Adult Superhero comic about twins who share superpowers. While trying to live a normal life in college, Marty and Eli Powers have to fight Dr. Atlas and his followers, whose aim is to obtain their powers for their own evil purposes.
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While the Senate has been busy voting on same-sex marriage this week, there’s been another, perhaps less important marriage battle brewing in the entertainment world over comments made by former Full House star Candace Cameron Bure.
But honestly, it’s cathartic for anyone who lived through the George W. Bush era to watch homophobic and bigoted sentiments receive the verbal tongue-lashing they deserve.
After peaking in the ’90s in her role the boy-crazy teen D.J. Tanner, Bure became a mainstay of the Hallmark Channel’s original films before abruptly leaving earlier this year for the conservative network Great American Family. In a Wall Street Journal interview published earlier this week, the actor said she wants to “keep traditional marriage at the core” of her new work — an especially pointed remark considering Hallmark’s first gay Christmas movie is about to premiere.
Bure’s comments have sparked a wave of justifiable outrage, most recently from country singer Maren Morris. “Make DJ gay again,” Morris commented wryly on a viral Instagram post by Matt Bernstein lampooning Bure’s comments — a possible reference to the Fuller House episode where DJ and Kimmy are called “luscious lesbians” after performing Dirty Dancing choreography together.


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Local Celebrity Chef Daniel Koh embarks on a new dining concept, Le Cuisine, which pairs the gratification of salads and casseroles with a blend of Eastern and Western gastronomy. Spot European cooking techniques flirting with familiar Asian flavours.
Chinatown Point, the latest retail mall in Chinatown popularised by its new makeover and inviting tenants such as Daiso and Thye Moh Chan, is probably the only mall in Chinatown that’s hangout-worthy for youths. The numerous eateries are a draw. Le Cuisine sets itself apart from the rest with its charming interior design, and casual yet gratifying dishes chaperoned with passion and care. The setting is decidedly cheery and casual – cut the formalities, minus the solemnness – catering to a wide audience.
Braised Lamb Shank ($15.50)
Chef Koh scores a major goal, with due credit going towards his unwavering focus on high calibre execution. The pricings are kept attractively affordable without compromising on quality; salads are priced from $7.80, mains from $13.50, and desserts from $5.50.
Mesclun Salad ($7.80)
Chef Koh’s Mesclun Salad is no rabbit food; the sweet and appetising homemade orange and raspberry vinaigrette imparts the much-needed vitality to the otherwise mundane greens. Adding more dimension and texture to the salad greens are raisins, apricot bits and pine nuts (just to name a few). I’m no fan of salads, but this is one of the few I would eat without grouse.
Chicken Liver Terrine ($10.80)
Terrines are one of my favourite things to eat with bread. The Chicken Liver Terrine is a more affordable alternative to foie gras terrine that I love endlessly. It is made up of 60% liver and 40% butter to yield a smooth consistency without the grittiness. This 80g portion might need more bread to accompany than just two slices! Plus, the crusty ciabatta is hard to resist. Traveling buddies include vegetable crudités served with a tapenade dip.
Six Sense Mushroom ($6.80)
The homemade cream of mushroom soup is chockfull of fresh mushroom bits, so much so you won’t even find this cream-based soup to be all that cloying.
Escargot Fricassee ($12.50)
The enticing Escargot Fricassee gratifies much more than a similar dish I had at an upscale restaurant. Morsels of succulent escargot arrive enveloped in a sensuous and creamy plot scattered with mushroom and homemade spinach gnocchi, overlaid by a lightly browned crust of breadcrumbs and melted Parmesan cheese. Heavenly.
Signature Crabmeat Burger ($13.50)
The Signature Crabmeat Burger is Le Cuisine’s best-selling dish. This bun-less burger comes with a succulent and substantial patty made of crabmeat and ebi (prawn).
Don’t we just love molten egg yolk?
Beef Stew ($15.50)
This beef stew is pure comfort. Intensely flavoured beef cubes are stewed in red wine with chunks of potato, carrot and zucchini, served with a blob of mashed potato and crusty bread.
Oven-baked Spring Chicken ($15.50)
One of the standout dishes for me would be the Oven-baked Spring Chicken, which I expected to arrive in the shape of… a chicken. Instead, the chicken is first deboned and rolled into a cylindrical shape. These succulent pieces are served with sautéed button mushrooms, zucchini and roasted potatoes. The chicken-based sauce is painstakingly made of a hearty amalgam of tomato, carrot, celery, leek and onion to name a few, receiving nods of approval with the cloak of umami.
Braised Lamb Shank ($15.50)
Highly compelling is the fork-tender Braised Lamb Shank, priced affordably under $20.
The spellbinding sauce laced with rose wine masks any apparent lamb ‘odour’. This dish alone prompts an immediate return visit.
Lychee Pork ($13.50)
I would give high ratings to the Lychee Pork dish based on the balanced and penetrating flavours, aside from the meltingly tender meat that left me yearning for more. The pork belly is cooked for 2 hours to deliver that desirable texture. The total prep time for this dish adds up to 4 hours! Thick slices of meat are served on a bed of coleslaw, and given an added sweet dimension with a topping of lychee pearls (commonly served in bubble tea beverages) that burst with the fruity sweetness of lychee ‘juice’. The combination seemed odd at first, but once you dig into it you will find that the sweetness of the lychee complements the meat faultlessly.
Pear Tart ($6.50)
Desserts are decent, but are no showstoppers, in a way that you wouldn’t visit this particular joint just to eat dessert. Le Cuisine is where you would travel to for superb and affordable mains.
Chocolate Fondant ($6.50)
Delighting chocolate lovers is the rich molten chocolate within the lovingly baked Chocolate Fondant.
Trio Chocolate ($6.50)
For a chocolate dessert less intense than the aforementioned, go for the velvety Trio Chocolate that comes with three types of chocolate mousse –as you can tell from the picture, they’re white chocolate, milk chocolate and dark chocolate.
Aloe Vera Jelly ($5.50)
My most recommended dessert to conclude the meal would be the light and refreshing Aloe Vera Jelly, served with a strew of fruits and fresh mint leaves.
Chef Daniel Koh is usually present at the outlet, personally overseeing kitchen matters to keep quality in check. During my dining experience, I chanced upon several groups of fans popping by to show their support and leaving with nothing but compliments for the food.
For an intimate gathering, secure the “Chef’s Table”, a 12-seater private dining room.
133 New Bridge Road
#B2-34/36 Chinatown Point
Opening hours: 11am to 10pm daily

domain: food


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There is something exciting about all election campaigns. There’s the intense analysis, the microscope that looks at every candidate’s individual word, and activities. There’s the ups and downs of polls that inspire and discourage people as they cheer on their favourites. There’s the push to get people up out of their chairs to the local community hub to vote, vote, vote! All this ends with a result that potentially lasts for the next four years – are you engaged in this excitement?
We’re now into the final weeks of the provincial election, and Election Day will soon be upon us. Many Ontarians have already had a chance to engage with candidates to talk about the key issues and how their parties would address them.
Ontario’s provincial election campaign is now in full swing, and across the province, candidates are engaging with voters in hopes of capturing their support at the ballot box. In turn, voters want to know where candidates stand on the issues that matter most to them.
Throughout the last two years, farmers and farm businesses have worked hard to adapt to the challenges created by the COVID-19 pandemic. That included ensuring Ontarians continued to have access to locally grown food and keeping farm workers and rural communities healthy and safe.
For decades, farmers have been losing prime farmland to urban sprawl. I have seen several productive farms turned into housing developments, soccer fields, shopping malls, movie theatres and highway extensions.
As farmers, we know that it’s the finite details that make all the difference. This could be closing the latch on a gate, applying the parking brake, or checking your blind spot when making a left-hand turn. Biosecurity includes a collection of those details to maintain safety standards and protect livestock and crops from potentially devastating disease outbreaks.
For the farming community, the tell-tale signs of spring trigger the countdown for this year’s growing season. Planting across the province has already commenced for frost tolerant crops like small grains, potatoes and sweet green peas. Throughout the winter months farmers have ordered inputs, maintained equipment and eagerly anticipated getting back into the fields. For many, planting requires travelling busy and potentially dangerous roads.
Ontario’s agriculture industry faces various challenges as our farmers work to create a stronger, more resilient sector that will sustain Ontario for generations to come. We depend on ongoing research, innovation and proactive initiatives to help find the solutions to meet these challenges.
The care, well-being and safety of livestock is of the utmost importance for farmers, especially in cases of transportation. Anyone involved in transporting animals, directly or indirectly, has the responsibility to ensure their livestock are ready for the journey.
Whether it be direct or indirect, the entire population has a connection to agriculture and the ongoing challenges within the industry. Rural or urban, we all rely on food, fibre and fuel to sustain our everyday lives.

domain: agronomy


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(AmericanProsperity.com) – State government-induced shutdowns of non-essential businesses and record unemployment forced US retail sales to drop to its worst decline on record. On Wednesday, the Commerce Department said retail sales took an astonishing dive of 8.7% in March. That’s the most significant decline since the government started tracking retail sales in 1992.
In February, the US was experiencing one of the best economies in decades. The March numbers only reflect a partial month of economic decline. Non-essential businesses in many states were ordered to close in the middle of the month.
Economists surveyed by Reuters expected retail sales to fall by 8%. The numbers reinforce the belief by economists that the economy is in a deep recession with no light at the end of the tunnel. While there were significant declines in retail spending, there were also a few bright spots. However, the good wasn’t enough to outweigh the bad.
Declines in Retail Spending
Retail businesses still overwhelmingly rely on people entering stores to make purchases. Two of the biggest segments of the retail industry saw significant drops in sales. Car purchases and vehicle parts dropped by nearly 26%. Additionally, as Americans hunker down at home, they’re unable, or perhaps even unwilling, to take advantage of significantly-lower gas prices. Gas stations reported a 17% drop in sales.
Retail sectors that saw drops included:
- Clothing and Accessories: -50.5%
- Furniture and Home Furnishing: -26.8%
- Food Services and Drinking Places: -26.5%
- Motor Vehicles and Parts: -25.6%
- Sporting Goods/Hobby/Musical: -23.3%
- Gasoline Stations: -17.2%
- Electronics and Appliances: -15.1%
- Misc. Retail: -14.3%
A Surge in Essential Shopping
In what can be described as essential shopping, grocery stores increased their sales as people panicked for items like toilet paper, food, cleaning supplies, and medications.
Retail sectors that saw an increase included:
- Food and Beverage: 25.6%
- General Merchandise: 6.4%
- Health and Personal Care: 4.3%
- Nonstore Retailers: 3.1%
- Building Materials and Garden Equipment: 1.3%
In a bright spot for people looking for work, both Walmart and Amazon reported strong internet sales. Both companies said they plan to hire tens of thousands of workers due to high demand. While internet sales are growing as people stay home, it’s unknown if the trend will continue post-COVID-19 when state governments lift lockdown orders.
However, some economists predict that brick-and-mortar stores that did not make the transition to online sales in recent years may struggle to survive long-term.
Consumer spending makes up approximately 70% of the US economy. While the economy was growing between 2% – 3% before the COVID-19 pandemic, economists say consumer spending could drop as much as 41% before rebounding.
Let’s hope that businesses can safely reopen soon and America can start rebuilding its economy.
~Here’s to Your Prosperity!
Copyright 2020, AmericanProsperity.com

domain: economics


Recently, I received a note from one of our SL’s (Smart Listener), who is also a subscriber to the Teri O’Brien Show. It read:
Do you know anything about this proposed Amendment to the IL Constitution? Do you know where I can find out the conservative view on it? On the surface it looks like something I’d support. But Mike Madigan sponsored it so that concerns me. I just don’t see how something like this that appears to be fiscally conservative could get through in IL. I don’t trust them!
First, let me say how much I appreciate this SL’s support of the show. It helps us keep the lights on. If you value the information you get here, and on the Teri O’Brien Show, please consider subscribing. As little as $5/month, makes a huge difference here. You can click on the yellow buttons on the right side of the top of the page to either subscribe, or make a one-time contribution. Thanks so much!
SL, your intelligence is showing, not only because you like the show, but because you view anything sponsored by current Illinois Speaker of the House and Chairman of the Illinois State Democrat Party Mike Madigan with suspicion. For readers who don’t know much about Mike Madigan, and why his involvement in any legislation raises a red flag, please check out this column from the Chicago Tribune’s always insightful John Kass. Mike Madigan runs the IL democrat party, and under its fine stewardship, this state his been run into the ground. It has $85 billion in unfunded pension liabilities and $8 billion in other unpaid bills. Businesses and productive citizens are fleeing the high taxes. Madigan accepts no responsibility for any of it.
So what does the amendment say and what would it do? To put it simply, as the folks at BallotPedia state “If passed, the measure would require a three-fifths approval by the General Assembly, city councils, and school districts that wish to increase the pension benefits of their employees.” Here’s the text, from the official Illinois General Assembly website. It would take effect on January 9, 2013.
This amendment is exactly what I would expect from the sleazy pols who run this state, with Madigan at the top of the garbage heap. It is a cynical attempt to allow him to pretend that he and his party, which runs this state, are doing something about the fiscal mess, when in fact it would do nothing to fix the real problem; specifically, that Illinois has spent billions it doesn’t have and has borrowed billions to keep spending.
So, is it good idea to require supermajorities to increase spending even more? As we say about chicken soup, it couldn’t hurt, but as a practical matter, it’s not going to fix anything, and voters shouldn’t be fooled into thinking it will. Does that mean we should vote against it? In my opinion, no. In theory, it’s a good thing. Public employee unions oppose it because they oppose anything that makes it harder to spend more on public employee goodies. One thing we need to do is pass some actual pension legislation that will shore up the system by requiring bigger employee contributions, higher retirement ages, and reduction in the amounts paid to cronies to manage the pension funds. This amendment doesn’t touch any of those things. The Illinois Policy Institute calls it a “do nothing” amendment, and they are correct. I will probably vote in favor of it anyway because I don’t want to send a message to the clowns in Springfield that I’m not concerned about their profligate spending. I also understand those who say not to vote on it either way, precisely because it’s a ridiculous charade.
The real solution to Illinois’ fiscal woes is to get rid of one-party control, and for people to stop voting for the democrats who have destroyed this state.