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Journal of Neurochemistry
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Recently Published Articles
- Fabp1 gene ablation inhibits high-fat diet-induced increase in brain endocannabinoids
Gregory G. Martin, Danilo Landrock, Sarah Chung, Lawrence J. Dangott, Drew R. Seeger, Eric J. Murphy, Mikhail Y. Golovko, Ann B. Kier and Friedhelm Schroeder
Version of Record online: 29 NOV 2016 | DOI: 10.1111/jnc.13890
Fatty acid binding protein-1 (FABP-1) is not detectable in brain but is highly expressed in liver. FABP-1 null (LKO) male mice on control, but not high-fat, diet had increased brain levels of arachidonic acid-containing endocannabinoids (AEA, 2-AG), correlating with increased free and total arachidonic acid in brain and serum; however, this dietary phenomenon was not observed in female LKO.
- You have full text access to this OnlineOpen articleRifampicin attenuates experimental autoimmune encephalomyelitis by inhibiting pathogenic Th17 cells responses
Ke Ma, Xi Chen, Jia-Cheng Chen, Ying Wang, Xi-meng Zhang, Fan Huang, Jun-Jiong Zheng, Xiong Chen, Wei Yu, Ke-Ling Cheng, Yan-Qing Feng and Huai-yu Gu
Version of Record online: 29 NOV 2016 | DOI: 10.1111/jnc.13871
Rifampicin, a broad-spectrum antibiotic, has neuroprotective, immunosuppressive, and anti-inflammatory properties. However, the effect of rifampicin on autoimmune disorders of the nervous system is not clear. In this study, we investigated whether rifampicin was beneficial to myelin oligodendrocyte glycoprotein peptide (MOG33–35)-induced experimental autoimmune encephalomyelitis (EAE) mice, the well-established animal model of multiple sclerosis (MS). We discovered that rifampicin is effective for attenuating the clinical severity of EAE. Our findings may be helpful for developing the therapeutic and preventive strategies for MS.
- Cerebrospinal fluid biomarkers as a measure of disease activity and treatment efficacy in relapsing-remitting multiple sclerosis
Lenka Novakova, Markus Axelsson, Mohsen Khademi, Henrik Zetterberg, Kaj Blennow, Clas Malmeström, Fredrik Piehl, Tomas Olsson and Jan Lycke
Version of Record online: 29 NOV 2016 | DOI: 10.1111/jnc.13881
CSF biomarkers reflect different aspects of the pathophysiology of multiple sclerosis. The present study investigated the influence of interferon beta and natalizumab on seven biomarkers and their correlation with clinical and radiological outcomes. The results indicate that CSF levels of neurofilament light protein (NFL), C-X-C motif chemokine 13 (CXCL13), chitinase-3-like protein 1 (CHI3L1), and chitotriosidase (CHIT1) correlate with the clinical and/or radiological disease activity, providing additional dimensions in the assessment of treatment efficacy.
- Role of a heterotrimeric G-protein, Gi2, in the corticogenesis: possible involvement in periventricular nodular heterotopia and intellectual disability
Nanako Hamada, Yutaka Negishi, Makoto Mizuno, Fuyuki Miya, Ayako Hattori, Nobuhiko Okamoto, Mitsuhiro Kato, Tatsuhiko Tsunoda, Mami Yamasaki, Yonehiro Kanemura, Kenjiro Kosaki, Hidenori Tabata, Shinji Saitoh and Koh-ichi Nagata
Version of Record online: 29 NOV 2016 | DOI: 10.1111/jnc.13878
We propose the role of a heterotrimeric G-protein, Gi2, in the brain development. We then identified a de novo heterozygous missense mutation of the α-subunit, GNAI2, in a patient with periventricular nodular heterotopia and intellectual disability. Although pathophysiological significance of this mutation remains to be clarified, gene abnormalities of GNAI2 might be involved in the pathogenesis of neurodevelopmental disorders.
- Pasireotide prevents nuclear factor of activated T cells nuclear translocation and acts as a protective agent in aminoglycoside-induced auditory hair cell loss
Daniel Bodmer, Adrijana Perkovic, Marijana Sekulic-Jablanovic, Matthew B. Wright and Vesna Petkovic
Version of Record online: 29 NOV 2016 | DOI: 10.1111/jnc.13880
Aminoglycosides such as gentamicin trigger a calcium ion influx (Ca2+) that activates pro-apoptotic signaling cascades in auditory hair cells (HCs). Pasireotide inhibits Ca2+ channel activity, preventing the accumulation of cellular Ca2+ provoked by gentamicin, thereby preventing the downstream events that culminate in nuclear factor of activated T cells (NFAT) activation. The cell-permeable peptide 11R-VIVIT interrupts the same pathway by binding to Calcineurin (CaN), selectively blocking its ability to activate NFAT. Our discovery of the protective effects of pasireotide and 11R-VIVIT, together with the characterization of their mechanism of action, suggests how we can rapidly reformulate a well-known drug for entry into clinical trials as a potential new therapy for hearing loss.


Dramatic Video from Miami Shows Alleged Hit-and-Run Driver Attacked by Onlookers
The alleged hit-and-run driver was attacked by witnesses, including one with a sledgehammer.
Cellphone video captured the intense confrontation between an alleged hit-and-run driver and onlookers who tried to stop him from leaving and used a sledgehammer to bust his SUV windows.
Witnesses said the driver crossed over a median in Miami and drove into oncoming traffic, hitting three cars before coming to a stop. At that point, multiple drivers get out of their vehicles and try to stop the man from fleeing. The video shows significant damage to his SUV, with the front grill hanging off the passenger side.
As onlookers screamed, the SUV lurches forward, makes a turn and gets stuck by cars trying to block his exit. A man gets out of a white van with a sledgehammer and proceeds to smash in the windows of the SUV, the video shows. The driver still manages to get away.
Police later identified the man as Maxwell Lagutenko, 25. He was arrested and charged with fleeing and eluding police, leaving the scene of an accident involving property damage and reckless driving. There were no reports of injuries.
He appeared Monday in court, where his bail was set at $5,000. He is being held at the Turner Guilford Knight Correctional Center, according to online records.
Lagutenko appeared to be high on narcotics, according to his arrest report, WPLG-TV reported.
He had been ticketed 18 times over the last eight years, according to court records, the Miami Herald reported.
He was found guilty 11 times and paid $2,387 in fines, the paper said.
Criminal records show he had been ordered to serve probation on convictions of delivering oxycodone, possession of drug paraphernalia and cocaine, possession of a controlled substance and violating a restraining order.
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By Dan Smith & Lori Baranoff
July 24 -- This week the Chesapeake Bay Executive Council – governors, the D.C. mayor, federal agency heads – convened for their annual meeting, this time at the National Arboretum on the Anacostia River. Their “big picture” focus on meeting major milestones necessary for a clean Bay by 2025 kept them from the river just down the hill -- where they may have glimpsed a bald eagle plucking a fish or a rower taking a lunch time canoe break on a gorgeous summer day. Those are river experiences we love to share and that show why this effort is so important.
Wild Celery underwater in the Susquehanna River. Credit: Debbie Hinkle, Chesapeake Quarterly
Submerged Aquatic Vegetation, The River’s Health Barometer
By: Audrey Pleva
Bladensburg, MD, April 27, 2015 – More than 2600 local residents and dozens of corporate partners came out Saturday April 25th to participate in the Anacostia Watershed Society’s Earth Day Clean Up and Celebration.
Plastic foam containers collected at our trash trap in Nash Run, a stream of the Anacostia River.
Earth Day 2015 Site Sketches: Wells Run Stream Buffer
Site Leader: Mary Abe
Phone Number: 301-699-6204 x106
Site Capacity: 50
Wells Run is a tributary of the Anacostia that has seen a lot of improvement in recent years, and the community is dedicated to keep making the stream healthier!
Wells Run runs through both the Riverdale Park and University Park communities before connecting to the NE branch of the Anacostia River. Compared to many tributaries of the Anacostia Wells Run is relatively trash free, but suffers from a lack of stream buffer vegetation, and in many areas the slopes leading to the stream bank are mowed grass.
By Dan Smith & Lori Baranoff
Challenged for much of the past year for requiring the state’s largest jurisdictions to set fees for local polluted runoff reduction projects, the Maryland General Assembly took action this week to give local jurisdictions flexibility in how they raise these important pollution-reduction funds. The Assembly also affirmed requirements that the work get done. The bill now goes to Gov. Larry Hogan for signing.
Volunteers scooping up plastic containers at our Earth Day Cleanup.
Bladensburg Waterfront Park, MD.
Site Leader: Marian Dombrowski
Contact Info: firstname.lastname@example.org
Site Capacity: 200
Quincy Run is a tributary that is near and dear to the AWS staff not only for its literal closeness to our offices but because it, like many other tributaries of the Anacostia, has quite the geography and history that works for/against it.
Quincy Run begins near MD 202 and the Baltimore/Washington Parkway and runs above ground* for just over a half mile. It begins in neighborhoods but quickly changes over to a large wooded site that receives a lot of trash due to dumping and blowing trash from people littering the roadways and businesses around the area.
Gateways consists of non-tidal wetlands with a total area of about 10 acres, the picture shows a pond located right in the middle of the wetland which normally dries out in late summer. This pond provides important habitat for aquatic plants, invertebrates, wetland birds, amphibians, reptiles and other organisms.
Stay informed of the latest watershed issues by subscribing to our free email updates & event announcements.

domain: geography


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Workers´ colony Karlov was built by Škoda Works in 1913 to accommodate the growing number of its employees. Attached to the factory´s walls and thus spatially segregated from the rest of the city, inhabitants of Karlov built a relatively close-knit neighbourhood community with a strong place-based identity. Based on the analysis of archival material and data from interviews with its former inhabitants, we follow Karlov´s voyage from capitalism to state-socialism at the levels of both macro-structural forces and its´ inhabitants´ experience of everyday life. Built to serve particular economic and political functions for the pre-war capitalist production, Karlov ceased to fulfi l these roles under state-socialism which refused to invest in Karlov´s renovation after serious damages caused by an air-raid during the WWII. Slowly losing its macrostructural raison d’être, Karlov was doomed to fi nal demolition in 1986, being represented as an “obstacle” to industrial development. Meeting regularly twice a year and recalling the past, former neighbours from Karlov actively revalidate their collective identity attached to a place that does not exist anymore, thus becoming real community of an imagined place.
The article examines the rise of informal spatial practices in the areas left in the shadows of the socialist planning system, in Belgrade (Serbia, former Yugoslavia) in the 1970s and 1980s. By looking into the relation of spontaneous interventions with the constitutionally enacted system of territorial self-management, we explore both the enclaves of everyday life forming in parallel to the hegemonic and homogenous plan, and highly formalised, planned attempts at emulating spontaneous practices in large housing projects. The research is based on comparative analysis of planning documentation and illegal interventions, period sources including letters and memos written by architects and illegal constructors, available statistics and published polemics. The article argues that many of the unresolved contradictions of the socialist period can be seen as the seeds of those practices which have been part of the post-socialist transition and its spatiality from the 1990s onwards. Indifference toward self-management, cynicism of the everyday in the blind spots of socialist society and the planning profession’s failure to deal with informality, are reproduced within the post-socialist city through unrelenting consumption of the common space
The paper interconnects studies of everyday life and everyday consumption and research on socialist housing estates. It is based on an ethnographic study of Petržalka, the biggest housing estate in Bratislava, located at the south bank of the river Danube. We develop two arguments. First, we focus on perception of the socialist housing estate by citizens of Bratislava, and analyse the role that everyday life and routine practices played in appropriating/getting used to this specifi c urban space. Also, we claim that everyday routine practices help creating the specifi c image of the housing estate in the eyes of the inhabitants. In the second plan, and in reaction to the literature on “lived socialism”, the paper argues for a more elaborate defi nition of socialist consumption that would reflect theories of everyday life.
Abstract: Cities in socialist Czechoslovakia were meant to constitute the setting for an ideal socialist society. The dogmatic embracement of this objective by the ruling Communist Party eventuated in complete intolerance towards any manifestation of free-thinking or alleged opposition to socialism. Starting in the 1960s, part of the Czechoslovak youth were inspired by the Western countercultural hippie movement and the Beat generation, as well as by punk subculture beginning in the 1970s. These people openly displayed their alienation from the offi cial culture by disrupting the established societal standards of appearance, behaviour, and leisure activities. The State Security saw them as ideologically biased, labelling them as the defected youth in an effort to eradicate their presence from the public space and separate them from other citizens. As Czechoslovakia’s capital and biggest city, Prague had the highest concentration of people inspired by Western countercultures. Their appearance, activities, and cultural production provoked the conformist society, and lead to the regime’s hostility and repressions. Unlike Western countercultures, which were based on political protest against their respective regimes, Czechoslovak alternative groups inspired by these countercultures were, in most cases, rather apolitical. In a time of post-1968 normalization, their anti-regime opposition originated mainly in the attempts of the totalitarian state to normalize their cultural aspirations. This paper explores the ways in which the context of socialist Prague affected the practices and routines employed by the fans of alternative culture throughout the.1980s, resulting in their antagonistic relation towards the totalitarian regime.
Ostrava, in the past nicknamed the steel city of the republic or the city of coal and steel, represented during the socialist period and afterwards the main ndustrial city of the republic. The social offi cial visual images of the city and life in it represented a happy urban life with glimpses of shining future. Ostrava was visualized as an embodiment of progress made possible and conditioned by the industrialization and related changes of the urban landscape and everyday life. The article presents the analysis of the offi cial visual discourse on the topic of the city of work and the everyday life of the people in it, constructed through the offi cial photographic publications on Ostrava. The main constitutive elements of these visual presentations are confronted with unoffi cial, rather ambivalent testimonies on the alternative urban landscape of the inhabitants of Ostrava, presented by artistic photographs (Kolář, Štreit, but also for example Polášek). The goal of the visual discursive analysis of this double material was the understanding of the basic constituent parts that together made the image of socialist Ostrava, as well as the role assigned to its inhabitants. On a general level the rich visual material made possible the deliberations upon the relationship of the photographic image and the visual discourse. Therefore I was able to show how by using the similar photographic themes connected with the everyday life and, therefore, by using very similar photographs two Ostravas were constructed – on the one hand the city of work, coal and steel and on the other the city of the everyday life.

domain: sociology


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While Jamaica is undeniably the birthplace and primary hub of dancehall music, the genre has gained popularity and influence globally, with artists and producers from various countries contributing their unique styles. Some countries that have embraced and produced notable dancehall music include:
- United Kingdom (UK): The UK has a vibrant dancehall scene, with artists blending Caribbean influences with their own cultural expressions. The London dancehall scene, in particular, has been influential.
- United States: Dancehall has had a significant impact on hip-hop and pop music in the United States. Many American artists incorporate dancehall elements into their music, and collaborations between Jamaican and American artists are common.
- Canada: Canadian cities like Toronto have seen a rise in dancehall-influenced music, and Canadian artists often infuse dancehall vibes into their work.
- Ghana: In West Africa, Ghana has embraced dancehall, incorporating it into its diverse music scene. Ghanaian artists often fuse dancehall with local genres, creating a unique sound.
- Nigeria: Nigerian artists, particularly in the Afrobeat genre, have been known to incorporate dancehall elements into their music. Dancehall has influenced the broader Afrobeat movement.
It’s important to note that while these countries have vibrant dancehall scenes, they often bring their own cultural influences to the genre, creating a rich tapestry of global dancehall expressions. Each region’s interpretation adds unique flavors to the genre while keeping the essence of Jamaican dancehall alive.

domain: artistic


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While in Portland for only a few hours, we found this pizza place right in downtown. They had the option of getting a GF and Vegan pizza. When we walked in, I was worried because it looked like flour was falling everywhere, it's not the cleanest place (which I think gave it it's charm.. You know typical pizza place) and the guys behind the counter looked like they really didn't care if they cross contaminated anything.
I was soon mistaken. The service was awesome, the pizza even more amazing with a sweet and flavorful sauce, and the bread was to die for. I am very sensitive to cross contaminations and wasn't pinching my stomach 30 minutes later. I was almost about to cry when I finished the last piece.
It took 20 minutes to cook so they advise us gf people to call ahead.
Location:28th Ave S,Seattle,United States

domain: food


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Harley Quinn - Arkham Knight - cosplay by Jessica Nigri © JwaiDesign, Jonathan Wai 2014
Pikachu costume idea. for the EDC Chicago 2013 - AMELIA
"I like this outfit... well done. Nice location for a shoot too." Jessica nigiri assassins creed cosplays
Steampunk Harley Quinn -Harley Quinn is my favorite. Future cosplay character.
Deathwing (World of Warcraft) #cosplay by Jessica Nigri | Blizzcon 2015
The most buxom and beautiful badass sponsor in all of Pandora: Mad Moxxi!!
Link cosplay by Jessica Nigri, Photo by Adam Patrick Murray
Harley Quinn Cosplay
Click (or copy/paste) to read more about commissioning costumes! http://geeknewsnetwork.net/2015/07/28/cost-custom-cosplay-money-go/
25 Ultimate Cosplay Ideas For Girls


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Diane Shaw, soul singer UK, travels worldwide. She was once described as the ‘most famous unknown UK singer’ and has probably performed in front of more people than most singers in the pop charts today.
Heralded as the freshest thing to hit the UK Soul scene in years Diane brings an enthusiasm and energy rarely seen on stage today. If you’re a Soul and Motown fan you’ll love this show – The Sound Of Young America – Motown ‘Live’.
Singers don’t come much more highly recommended than this fine lady. And if you’re looking for a Soul or Motown singer for your event enquire today. This is a popular music genre that originated in the United States in the late 1950s and early 1960s. It combines elements of African-American gospel music, rhythm and blues and jazz.
Soul Singer UK Diane Shaw
Soul music became popular for dancing and listening in the United States, where record labels such as Motown, Atlantic and Stax were influential during the Civil Rights Movement. Soul also became popular around the world, directly influencing rock music and the music of Africa.
According to the Rock and Roll Hall of Fame, soul is “music that arose out of the black experience in America through the transmutation of gospel and rhythm & blues into a form of funky, secular testifying”. Catchy rhythms, stressed by handclaps and extemporaneous body moves, are an important feature of soul music. Soul music dominated the U.S. R&B chart in the 1960s and many recordings crossed over into the pop charts in the U.S., Britain and elsewhere. (Wikipedia)
Listen To Diane Shaw Soul Singer
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domain: entertainment


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BAKERSFIELD, Ca. – A stabbing on Monday, October 21, 2019, left a man dead authorities said.
At around 8:15 a.m. deputies were dispatched to the 1000 block of Lomita Drive in the City of Bakersfield for the report of a stabbing. When they arrived they located a man suffering to tauma to his upper body, sheriff’s officials said. The victim was rushed to the hospital where he died as a result of his injuries.
Through the investigation, 26-year-old David Valles of Bakersfield was identified as the suspect in the case. He was located in the 900-block of South Union Avenue and taken into custody without incident. Valles has been booked into the Central Receiving Facility and is charged with murder.
The victim’s name is currently being withheld pending the notification of the next of kin.
Homicide Detectives were called to the scene and assumed the investigation. The investigation is ongoing ,anyone with information is asked to contact the Kern County Sheriff’s Office at (661)861-3110 or the Secret Witness Hotline at (661)332- 4040.
This article was written by a staff member of the 24/7 Headline News Organization
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domain: news


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My friend G has been talking about this for over a decade. I finally decided to try it one Shabbos. I realized that this is not a salad, but a showstopper! My family and guests had triples of it, and of course everyone was nibbling on the topping before, during, and after! I made it recently for the sheva brachos I hosted for my niece that was milchig. The topping was, well, over the top! Enjoy both versions!
Combine all nuts together in a small bowl. Melt margarine, brown sugar, and salt together in a large skillet. Add the nuts and mix together. Continue stirring, over medium heat, until nuts are coated and fragrant, about 10 minutes. Remove from heat. Let sit in pan for about two minutes.
Pour out onto a piece of Gefen Parchment Paper, sprinkle with black pepper to taste, and mix together until coated. Set aside. (I suggest putting this by your neighbor or at least in the back of your fridge, or it will be gone. The sweet/salty/peppery combo is beyond!)
Combine all dressing ingredients in a small container and shake well. Pour over salad and toss together right before serving. Sprinkle topping over the salad and serve.
I don’t recommend replacing the margarine with oil. Taste of crunch will be compromised. You can use butter-flavored margarine to enhance the flavor. Use butter for a milchig meal.
For a lower-fat version of this salad, when I doubled the recipe I did as follows: 1/4 cup oil + 3/4 cup water, 3/4 cup vinegar, 3/4 cup sugar, and 1/3 cup soy sauce. Also I used 6 tablespoons margarine for the crunch rather than 1/2 cup. I present both versions for your convenience. The crunch can be made in advance and stored in the fridge.
Photography: Daniel Lailah.
Food Styling: Amit Farber.


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Pulse oximeters generally work by shining a light through a relatively transparent area of the skin. The light shines through to a detector positioned on the other side of the skin.
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TabletShablet provides you with the range of Accusure, to help you & your family stay healthy and fit at all times.
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Beautiful Intimate Backyard Wedding
A Wonderfully Witchy Wedding
This beautiful couple chose to have an intimate wedding ceremony in the Bride’s childhood backyard. It was such a beautiful ceremony. From crystals, to a handfasting ceremony to a small brunch with a vegan cake, this couple made their wedding day so meaningful and special. Even the Bride’s DIY Bouquet included a small trinket with a tuft of bunny hair from her beloved pet rabbit. I love how DIY weddings include so many meaningful details like this. Seriously tugs at the heartstrings.
After brunch we headed back to Fort Lauderdale to one of their favorite coffee spots for some portraits and frolicked in some woods nearby. They ended their wedding day with celebratory beers at Funky Buddha Brewery.
I freaking LOVE when couples do what they want for their wedding day. It truly becomes about them, and their union, as it should be.
Here are a few of my favorites from this magical, witchy wedding day!


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91 books — 6 voters
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“ I haven't waited to be summoned for my big moment by a tap on the shoulder from a mysterious, benevolent stranger. It doesn't work that way where I'm from. You make your own opportunities where I'm from. ...more ”
“ in the abstract art of cooking, ingredients trump appliances, passion supersedes expertise, creativity triumphs over technique, spontaneity inspires invention, and wine makes even the worst culinary disaster taste delicious. ”
Join novelist, food lover and chef extraordinaire as she discusses her debut work "Aftertaste: A…more
[close] Join novelist, food lover and chef extraordinaire as she discusses her debut work "Aftertaste: A Novel in Five Courses." Come talk about food, romance and literature -- the trinity of happiness! This group will be active 9/12-30, 2011.
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[close] For those who love culinary crime fiction. We highlight culinary mysteries, food based fiction and other literary bites.
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This is a place to discuss the works of author Kathleen Flinn, the author of "The Sharper Your K…more
[close] This is a place to discuss the works of author Kathleen Flinn, the author of "The Sharper Your Knife, the Less You Cry," "The Kitchen Counter Cooking School" and "Burnt Toast Makes You Sing Good" (all Viking/Penguin). Swap recipes, get exclusive unpublished recipes, ask questions, get tips for visiting Paris, discuss the food memoir genre, writing tips, whatever suits your fancy. Plus, learn about events to meet up with Kathleen in person.
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All Things Culinary Mystery
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Tags contributing to this page include: culinary and culinary-literature

domain: library


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Cannabis could be the catch that is new of Canadian commerce. From the time the Cannabis Act was passed away in Ontario, on 17, 2018, and, even before, a lot of research has gone into the applications and advantages of cannabinoids october.
The favorite that is pop-culture of possibly Tetrahydrocannabinol, THC because it’s colloquially understood, because of its psychoactive nature. But, there are several other forms, that could be possibly advantageous to us.
Endocannabinoids are organically created by the body, produced by the endocannabinoid system. Endocannabinoids have already been discovered to aid within the regulation of rest, discomfort and also the reactions for the system that is immune. Cannabis scientists have now been investigating the part of physiological cannabinoids in tissue disease and recovery. It really is fascinating that the endocannabinoids activate the receptors that are same the psychoactive THC.
How can you use cannabis oil for relief of pain?
Phytocannabinoids happen naturally in cannabis flowers. You can find fifteen subclasses of these substances. THC, cannabidiol, and cannabidivarin are samples of exactly the same.
Cannabidiol (CBD) is a subclass of Phytocannabinoids and another among one twenty cannabis substances. It really is hailed for the power to be meditative, without producing a euphoric high. This non-addictive miracle cannabinoid happens to be the talk of this city in addition to core of various experiments. The anti-inflammatory properties of CBD have encouraged the advertising of their by-products, such as for example CBD oil, for discomfort relaxation and relief.
What is CBD oil?
CBD oil is obtained through the hemp that is industrial, Cannabis Sativa. The seeds associated with the hemp plant are pushed before the natural natural oils are released. This is just what makes cannabidiol different from and less psychoactive than THC, that is removed through the cannabis plant, https://cbdoilexpert.net/cbd-vape-oil Cannabis Indica. The commercial hemp oil has traces of THC with it, about 3% in effectiveness, perhaps not enough in causing a ‘high’. Despite its non-addictive nature, CBD oil might need a medical prescription for appropriate acquisition in a few provinces.
So that you can remove undesired elements such as fats or waxes, CBD oil is put through an ongoing process called ‘winterization’. Refined cannabidiol oil is stirred with alcohol and deep-frozen overnight. A Butcher channel or an item of paper will be utilized to filter the fats away. Finally, the extracted oil is heated to your boiling point of alcohol and so the alcohol evaporates.
Just how can CBD oil be consumed?
As opposed to popular opinion, the outside application isn’t the best way through which CBD oil could be consumed. By putting it underneath the tongue, many consume CBD oil straight. CBD oil has additionally been innovatively infused into items such as for example moisturizers and creams that are topical. CBD oil is definitely a acceptable food health supplement, serving as an addendum to snacks, brownies as well as tacos! CBD oil capsules are a way in which they could be ingested.
How does cannabidiol help reduce pain?
As a whole, the human anatomy has certain web sites which can be allotted to cannabinoids, called the cannabinoid receptor web sites. Receptors are mechanisms to that your cannabinoids naturally contained in the body as well as the people artificially ingested/ used attach themselves. You can find two forms of receptors for cannabinoids, the CB1, additionally the CB2. Whilst the CB1 receptors can be found within the brain, the CB2 receptors can be seen in the immunity system.
Cannabinoids could be agonists, inverse agonists or inhibitors. The agonists just stimulate a bodily function once they abide by their respective receptors. Inverse agonists associate themselves aided by the receptors that are same agonists, while causing a chemical reaction other to your people brought on by agonists. Inhibitors just stop a reaction that is chemical reaction as soon as bound for their receptors.
Cannabidiol is exclusive, since it doesn’t work aided by the CB1 or CB2 receptors. It passively influences the working of this Endocannabinoid system, managing the reception of pain, disease fighting capability functions and also the procedure of dropping and remaining asleep. CBD additionally amplifies the effect of most cannabinoids that affix to the CB1 receptors.
Interestingly, CBD oil protects the human body against unique euphoric stimulant. An endogenous cannabinoid, Anandamide, is produced on need by the body that is human. ‘Ananda’, in Sanskrit, means ‘bliss’. Anandamide, hence, creates a runner’s high, and also this is managed by Cannabidiol. This promotes pleasure on the usage of cannabidiol or CBD oil.
CBD normally thought to have anti-tumorous properties. GPR55, a receptor which has shown to proliferate cellular manufacturing and are likely involved in cancer, is inhibited by cannabidiol. More research is needed to establish the text between CBD and GPR55 plus the possible effects.
Some great benefits of CBD Oil
Cannabidiol happens to be widely accepted as an anti-psychotic member for the family associated with cannabis family members. Ongoing studies have involved inspecting the application of CBD in assisting victims of Post-Traumatic Stress Disorder.
CBD oil has positively which can subdue outward indications of anxiety, to your degree that the united states Food and Drug Administration has authorized the application of Epidilolex, A cbd that is patented medicine to treat epilepsy while the repetitive seizures induced by the condition.
Likewise, CBD oil could be effective when you look at the remedy for stress-related physical afflictions.
Several Sclerosis is an ailment when the system that is immune responds abhorrently to healthier cells and organs. Also called a disease that is autoimmune numerous sclerosis causes reoccurring spasms and enduring pain, for all those impacted. Even though impact is modest, CBD oil, acting as an anticonvulsant, might help in mitigating the amount of spasms caused, plus the resulting pain.
Perhaps one of the most profound uses of cannabidiol oil is for the relief of arthritic discomfort. You will find two forms of joint disease, rheumatoid and osteoarthritis, both leading to inflammation and stiffness in bones. Scientific studies have actually documented that the application of CBD oil will help assuage the pain sensation brought on by inflammations. Outcomes have already been encouraging. Wellness associations in addition to government, alike, are optimistic about the part of CBD oil in bringing solace to arthritic patients.
Of the numerous developmental disorders, autism and its particular associated spectral range of disorders are probably the many pervasive. Autistic kiddies have problems with sleeplessness, irritability and a loss in appetite, to mention a few. Practitioners have already been trying out the employment of CBD oil in curtailing the social anxiety and psychological manifestations vicariously triggered in victims of autism.
A paper by Cassuto and Lubotzky reported the decrease in the amount of behaviour outbreaks in autistic young ones treated with medical cannabis, especially Cannabidiol. Likewise, communication and anxiety problems were mitigated. Thus, CBD oil may have the next when you look at the remedy for the observable symptoms of autism spectrum disorders.
Cramps, chronic discomfort, and addiction
There were a quantity of studies investigating the conceivable a part of CBD oil in vanquishing pain of most proportions, be it menstrual cramps or discomfort of the magnitude that is chronic. The Journal of Experimental medicine speaks about the utilization of CBD oil for suppressing pain that is neuropathic rodents. In spite of the fact such studies are however to be replicated with people, CBD oil is an excellent tolerance-builder, a realtor that enhances the physique’s ability to handle and be resilient to pain.
Also, CBD oil may be called the antithesis of cannabinoids, which help in the cessation of smoking and also other improvements. Scientific scientific studies are charting the data when it comes to exact exact same.
It really is clear that CBD oil has a true quantity of functions in pain alleviation and legislation. But, you can find a few arguments which can be worthwhile considering. One is the usage of CBD oil for kiddies. The influence of CBD oil on the developing brain has yet to be deemed unintrusive although proven to be a player in autism-symptom mitigation. It’s still not advised that CBD be applied extensively on young ones. The recommended dosage of CBD oil for kids and grownups, both, must certanly be determined in consultation with a health care provider.
CBD oil may also cause fatigue, diarrhoea and weight that is sudden loss, according to each individual’s ability to metabolise or a reaction to the substance. That is why, it is usually important to check the usage of CBD oil in limited batches before delving in to a long-term cure.
At times, multiple cannabinoid substances are used together, either knowingly or unwittingly. It really is, thus, tough to discern the level to which each mixture is associated with evoking the desired effect. You will find instances when a combined number of cannabinoids works synergistically in contributing to bodily reactions. Studies CBD that is selectively employing oil few in number, but promising.
To close out, the increasing utilization of CBD oil as a substance that is therapeutic inspired many applications. But, care should be exercised whenever choosing CBD as being a nutritious substitute for allopathic medicine for pain.
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domain: chemistry


New curfew for NCR – 8:00 P.M. to 4:00 A.M.
MANILA – The city and municipal executives agreed to enforce an 8:00 P.M. to 4:00 A.M. curfew for the National Capital Region beginning Friday, August 6,2021.
The curfew will correspond with the enforcement of the enhanced community quarantine (ECQ) in Metro Manila.
MMDA Chairman Benjamin C. Abalos said at today’s Malacañang Press Briefing the liquor ban will be left to local chief executives.
“There are LGUs saying they have no liquor ban, including Makati, Taguig, Pasig and Las Piñas and Valenzuela, Mandaluyong, Parañaque, Pasay, Navotas, Pateros, Quezon City and San Juan where the ban’s enforced,” said the MMDA chair.
It will be recalled President Duterte approved the recommendations from the Inter-Agency Task Force on Emerging Infectious Diseases to place the NCR under the strictest lockdown from August 6 – 20 to stem the rise in COVID-19 cases further aggravated by the Delta variant. (Melo M. Acuña)
MMDA Chair Benjamin "Benhur" C. Abalos speaking at the Malacanang Press Briefing at midday today. (Screen grab/Melo M. Acuña)


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By: Diane Benjamin
This meme popped up on Facebook about the same time The Normal Town Council proved it to be true:
Start with the Work Session Normal had on December 7th to decide whether to create an ordinance to enforce Pritzker’s non-enforceable Restore Illinois waste of paper. See the video in this story: https://blnnews.com/2020/12/08/normal-isnt-shutting-down-businesses-for-violations/
Go to 4:58. Pam Reece wondered if the Council is interested in PENALTIES.
Go to 6:00. Pam Reece talks about a “carrot” approach.
Now for what happened last night:
If Restore Illinois is law the Town of Normal wouldn’t need an ordinance to enforce it. Most on the Council refuse to understand that.
Watching the faces on Zoom is priceless. I almost think they should stay on Zoom instead of in person so the disgust for common sense is readily apparent.
Go to 54:20. The discussion of this ordinance has been going on for awhile at this point. The proposed ordinance states liquor license fees will be waived next year as long as the establishment complies with Restore Illinois. The (last term) Mayor decides to put his own spin on it: He thinks this is the Town’s way of supporting small businesses. He doesn’t want the words punishment and rewards used in the discussion. He thinks the ordinance isn’t meant to do either.
Keep listening – next Stan Nord proposes an amendment to remove any language requiring compliance to get the fees waived. The vote was 6-1 to keep the PUNISHMENT in the ordinance.
Yes, folks we are all conspiracy theorists for using their own words and votes!
See 58:30 Stan Nord again. He asked what the Town response will be if an establishment chooses to pay the license fee and stay open. Attorney Brian Day states the police will still be used to harass those who don’t comply. The Koos statement of 11/2 where he stated complaints would be forwarded to the Health Department was also a lie. The Town is choosing to inflict as much pain as possible on those who aren’t kneeling before them. Next week a hearing will be held to fine one that is not complying. Later Stan Nord wasn’t allowed to discuss what other Illinois cities are doing by Chris Koos, soon after Pam Reece compared Normal to Bloomington. Koos was silent. (hypocrisy!)
The Town of Normal is holding a carrot in one hand and a sledge hammer in the other. Entrepreneurs struggling to survive get to pick a hand.
Jump to 1:05:00. Pam Reece proclaims the ordinance isn’t a bribe because that would be illegal.
The Council had the opportunity to remove the penalties for non-compliance with Pritzker. They did not do it. Therefore they are bribing local businesses to comply!
Kevin McCarthy, Chemberly Cummings, and Scott Preston will be on the April ballot. Of course Koos will be too. All conspiracy theorists need to show up and vote! Wear the badge proudly.
The rest of the meeting didn’t get any better.

domain: law


What is Aluminium 6082 Bar
Rexton steel & alloys is the esteemed company which is involved in offering the widespread variety of the ALUMINIUM 6082 Bar. This bar which is offered by them shows high resistance to corrosion. It is also one of the metals which retain the silvery reflectance in the form of powder, making it the essential element of the silver colored paints. There are a number of applications where these bars are used and this is the reason why Rexton steel and alloy is offering it in bulk to those who are in need of it.
There is no compromise made on the quality of the product and there is used best technology as well as methods to produce these bars. The skilled worker gives their hands and puts efforts to manufacture these bars appropriately without any errors. They make sure that the bars produce have an excellent surface finish and are polished well so that there is no rusting.
Common forms in which ALUMINIUM Alloy 6082 Round Bars are available are round, square, flat and hex. The length can vary depending upon the needs of the customer and the finishing given to these bars are black & polish or bright. Size of these bars may vary from 1/4” Dia to 16” Dia. when the bars are manufactured they will be made to undergo some important tests and inspection process.
These tests help analyze the strength and durability of the bars which are produced. Also, these tests ensure that product manufactured is of high quality and possess all the desired quality. There are a number of tests like a tensile test, eddy current test, heat test, corrosion test, pitting corrosion test, hardness test, elongation test. Some important test includes PMI test, IGC test, and the macro & micro test.
As soon as the product is tested it is allowed to be inspected for errors carefully by the third-party. They check the product and a report are made by the third-party which will tell that product can reach the market or not. They approve the product and then it packed. Packing is usually done as per set industrial standard. The packaging material used is usually durable as well as environment-friendly that means no harm is caused to the environment as well as product.
mostly the packing material used for the bars are the foils, poly bags and the wooden crates however the other packing materials can be also utilized if requested by the customers. The manufacturer will guarantee to deliver the product in the best possible condition. The delivered product will have a lot no, serial number, grade of bars, etc mention on the top.
Customers don’t wait to wait for a long to receive the desired product. Only 10 to 15 days are needed to deliver the product to the destination. A priority is given to the customer’s satisfaction and all the work done is in order to make the customers happy and satisfied. In case the customer asks for some test certificates from the manufacturer, the manufacturer will provide it happily.
ASTM B221, B211, B565, B316 6082, DIN AlMgSi1
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(New Artist/New Single) @SarshaSimone "Casualty"
Here's a new upcoming singer/songwriter coming straight out of Sydney, Australia; the singer's name is Sarsha Simone. Yesterday she made her first debut by premiering her debut single "Casualty" on RnBass's website. I want everyone to go buy her new single on iTunes out right now, share it to friends and spread her name out there. Hopefully we get to hear a lot more from Sarsha so stay tuned and keep your eyes out on her.
"Casualty" on iTunes Now: https://itunes.apple.com/au/album/casualty-single/id1116318900


text:
Log in with Facebook to find out who you know in this Meetup.
"Sci-Fi fan for many years. Lots of TV favorites, not many hates. Heinlein/Asimov were early authors I remember reading."
"I am a fan of SC-Fi and Star Trek is one the shows that I like to watch."
"Hi, I come from a long line of Sci-Fi watchers. My mom used to watch The Twilight Zone with her father. So I was born into it. I"
"I'm a senior web developer for a company in Omaha, NE. I am a lifelong Sci-Fi fan, computer geek, video game lover, dog trainer, chef, and avid book reader. "
"I'm a SciFi fan going back to early childhood."
"I'm a Florida girl trying to figure out life in North Carolina. I love meeting new people that I can nerd out with."
"Sci-Fi nut from ST_ToS & Johnny Quest. My favs: B5, Firefly, Paradox, Defying Gravity, Continuum, Eureka, Awake, ReGenesis, SG1, Max Headroom, Middleman, ST_DS9,..."
"Total Star Trek Fan. Why hadnt I joined sooner? I was caught in a worm hole. And YES! I met Leonard Nimoy, William Shatner, and Kate Mulgrew at this last years..."
"Hi, my name is Sharon; I love making new friends."
"it's gonna be a great day!"
"Hey, I work at an engineering college doing Web development and have enjoyed good sci-fi since I was a teen reading Heinlein. I'm interested in developments..."
Help support your Meetup
We started as a group of folks with Star Trek in common, but we have since discovered we are more than Trekkies. We talk about all things Sci-Fi. We get together for many fun and friendly meetings and group events.
535 Raleighfreyans & Dur-leks
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Street View is the best available vantage point looking, if possible, towards the location of the building. In some locations, Street View may not give a view of the actual building, or may not be available at all. Where it is not available, the satellite view is shown instead.
Latitude: 50.9861 / 50°59'9"N
Longitude: -2.1896 / 2°11'22"W
OS Eastings: 386788
OS Northings: 120760
OS Grid: ST867207
Mapcode National: GBR 1XW.575
Mapcode Global: FRA 669H.W7V
Entry Name: Horders Farmhouse
Listing Date: 16 August 1960
Source: Historic England
Source ID: 1110275
English Heritage Legacy ID: 103019
Location: Melbury Abbas, North Dorset, Dorset, SP7
District: North Dorset
Civil Parish: Melbury Abbas
Traditional County: Dorset
Lieutenancy Area (Ceremonial County): Dorset
Church of England Parish: Melbury Abbas St Thomas
Church of England Diocese: Salisbury
ST 82 SE MELBURY ABBAS FRENCH MILL LANE
8/179 Horders Farmhouse
Farmhouse, C18. Coursed rubble walls. Gable-ended roof, thatched to
the left and tiled to the right. Brick stacks to gables and part way
along ridge. 2 storeys, 4 irregular window range. Mainly 2-light
casements with glazing bars. Partly surrounded by later outshuts.
Listing NGR: ST8678820760
This text is from the original listing, and may not necessarily reflect the current setting of the building.
Other nearby listed buildings


NEW YORK, NY -- (Marketwire) -- 02/11/13 -- eMusic, a leading download-to-own music retailer, now allows all consumers -- regardless of whether they pay a monthly membership fee -- to purchase music from the online store. Beginning today, anyone can visit eMusic.com and purchase as many songs or albums as they want at retail price. The move makes eMusic more accessible to everyone, which is appealing to consumers and business partners alike, according to eMusic President & CEO Adam Klein.
"For nearly 14 years, eMusic has been devoted to music collectors who support artists and labels by purchasing their albums. That's why our base is comprised of culturally independent thinkers and music enthusiasts who are considered to be the tastemakers of the industry," Klein said. "Although our focus on this audience hasn't changed, our new business model is more inclusive and invites everyone to engage with what eMusic offers: insightful editorial that we curate independent of our sales division, and personalized discovery technology that draws upon the diverse tastes of our unique eMusic community."
Until now, eMusic has operated by subscription only. For a regular, pre-paid amount each month, eMusic members could -- and still can -- download and own music at discounted prices. Now eMusic will open its doors to everyone, allowing music consumers to access its industry-leading personalized discovery tools and features, and its catalogue of songs from every major label and nearly all of the independent labels.
"We hope the new business model will encourage an even broader audience to become buyers of music and, ultimately, music collectors," Klein said. "We also hope it makes eMusic easier than ever before for potential business partners to work with us."
eMusic's evolution signals its anticipated growth -- and new opportunity -- to current and prospective business partners.
"A number of major players have already taken interest in eMusic's new business model, which is making the brand more flexible and easier to partner with than ever before," Klein says. "We are in talks with potential partners in the OEM market, and also with wireless and cable operators, as well as big box retailers."
Since its inception, eMusic has been committed to serving serious music collectors who are unbound by genre or the latest trend. With a mission to provide culturally independent music enthusiasts and tastemakers with the best music and discovery experience possible, eMusic curates independent editorial content and music reviews. It has unparalleled experience in the online music space dating back to 1998, with a focus on innovative development of tools designed to enhance personalized music discovery.
Headquartered in New York with an office in London, eMusic is available in the U.S., Canada, the E.U., Norway and Switzerland. eMusic.com Inc. is owned by Dimensional Associates, L.L.C. the private equity arm of JDS Capital, L.P.
For more information, visit eMusic.com.
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eMusic Manager, PR & Communications
Twitter @eMusic / Facebook.com/eMusic
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ARTICLES BY MARK F. WITCHER
FMEA Vs. System Risk Structures (SRS): Which Is More Useful?9/24/2021
In this article, Mark Witcher, Ph.D., discusses the many failure modes of FMEA and risk priority number (RPN), comparing and contrasting it with system risk structures (SRS) and adjusted risk likelihood (RPN). He concludes that one of these is more useful than the other for pharma and medical devices; which one is it?
Why Controlling CQAs Isn’t Good Enough For Gene & Cell Therapies3/31/2020
It's frequently stated in the biopharma industry that to control a product’s critical quality attributes (CQAs) one must control the process’ critical process parameters (CPPs). While the statement is accurate literally, it does not convey the true technical requirements for controlling product quality.
3 Keys To Realizing FDA’s Vision For CAR-T And Other ATMPs12/12/2019
While cell therapy remains a very promising approach to developing much-needed new immunotherapies, significant challenges will have to be overcome in order to realize the FDA’s twenty-first century vision of making complex ATMPs widely and cost effectively available to patients.
Developing And Manufacturing Cell & Gene Therapies: Do Biopharma Methods Apply?9/3/2019
Are the methods used for developing the current generation of biopharmaceuticals, monoclonal antibodies, hormone replacements, etc., applicable to the next generation of Cellular and gene therapies?

domain: biology


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The gun went off and I looked down and saw my own blood. “You’ve got me.”
By MaiMai URL on 04.18.2011
Listening to something that completely man made drowns out the sound that needs to be heard. Listen to the natural sound and find meaning in it’s depth.
By Marshay on 04.18.2011
The acoustic guitar was beautiful, possibly the most beautiful gift he had ever received. He strummed the strings gently, and was rewarded with a soft melody. It was a tremendous gift for him to receive-the ability to make something.
By kait on 04.18.2011
By Jawni on 04.18.2011
The beautiful music streamed from the acoustic guitar as the boy sang along, his eyes closed as he sat beneath his large oak tree, singing a song that was rather close to his heart. He was completely unaware of the girl sitting up in that tree, listening to every melodical word that escaped his lips.
By Valerie on 04.18.2011
By far one of the most soothing forms of music. Rainy days and depressing times call for it.
By megan URL on 04.18.2011
My sister Kendel and my brother Shep are in a band. They love to do acoustic covers on songs.
By Linden on 04.18.2011
Simple sounds rise from the raw instruments sensing time with closed eyes. I felt in love with your ripe emotion flowing from dark eyes. Rivers of melody cascaded beneath our feet with our first hope.
By Emma Leigh URL on 04.18.2011
I remember the day I got my first guitar, red shiny, vinal strings, with the acoustic sound that I adore. It was my fathers before he died, but now it was mine.
By Alyss URL on 04.18.2011
i love the sound of a guitar as it strums through my feelings pierces through my soul soothes my heart eases my mind. light candles to relax to allow my fears to float away making the evening light. causing a smile where once was a frown.
By LaRaine on 04.18.2011
I cant play acoustic guitar and I am actually not even musical at all. So I don’t really think of much when I see the word acoustic but relate it to a guitar. I actually think of my friend Joshua Johnson when I see acoustic because after I relate it to the guitar I relate it to the only person that i know that has played the acoustic guitar for me and that is him its funny because we just talked about it today.
By Barun on 04.18.2011
my guitar is probably my favorite thing. it can always make me happy. anyone playing guitar for me also makes me happy. or if i pretend that they’re playing for me. music is such a big part of my life.
By fenderbaby URL on 04.18.2011
When I was about 13, my closest cousin decided he was going to learn how t play the acoustic guitar. He actually started off pretty, and unlike most young musician, he had a knack for cool lyrics that I was able to connect with at the time…probably because we were both in the 7th grade. Anywho, some
By Emilio on 04.18.2011
still acoustic. still sounds soft pittering, tattered, eyeing one another, timid. still acoustic. still so salty, the nostalgia.
By Al(l) is on(e) URL on 04.18.2011
the simple music I hear when everything every thing is turned off.
By cathy on 04.18.2011
music, pure music. the music that plucks, not blasts its pure and warm. the sound of just wood and voice mixed together with nothing elsejust strumming, no bass or clashes.
By haleigh on 04.18.2011
There was so little time to adjust tthe acoustic level in the chapel before the service began. Everyone over the age of adolesence held their hands over their wars. The kids were all grinning as the music pulsed, the drums nearly lifting the carpet off the floor. Finally someone reached the controller and silence was imposed on the still vibrating space
By Carol on 04.18.2011
Jenny sat in her treehouse and listened to the birds sing. She brought up her acoustic guitar to play a song. She wrote a song up there and is trying to get her career started with it.
By claire on 04.18.2011
Is an instrument that makes me really happy.maybe Ill learn how to play it someday. It provides amazing music and endless possibilities. :)
By claire bear URL on 04.18.2011
I like your tune,
Twing twang and
Everything in between.
I like your nature,
That beautiful soul
pouring from your lips.
You invite me on stage.
I’ll stay here in the crowd
Dancing with strangers, adoring.
Acoustic notes and lies.
By fish URL on 04.18.2011
Authentic, powerful, and is the essence of musical creativity. Not electric, dad, garage band time, fascination and I wish I could do it too. A strong, meaningful sound, enables you to play and express yourself.
By Sunny on 04.18.2011
i prefer music this way. more emotional. sounds more original and makes the song a little sweeter. my favourite songs are all the acoustic versions. more heart is put into it and the singer always seems to have more emotion.
By email@example.com on 04.18.2011
drumming at my fingertips, my soul sets fire. surfing sound waves passionately, my heart opens and flutters. calluses built up at my fingertips, toughened by time and practice.
By beachbumrach URL on 04.18.2011
He picked up his acoustic guitar (one of 6, may I add) and played her one of his songs. She couldn’t help but be mesmerized. Who wouldn’t want their own personal troubadour?
By Lizzy URL on 04.18.2011
acoustic guitar in the hands of a minor is a weapon of for heads and hearts pleasure the youth give pleasure
By dave URL on 04.18.2011
Sitting back in the leather chair and listening to Borg sing in harmony you can tell that the workmanship to make the acoustic sound amazing in this small recording
By Linda Berryman URL on 04.18.2011
singing without background music like adele. Sounds a bit stranger than usual but pretty good. The colour of the writing matches the kind of peaceful nature of the type of music so does the shape of the writing, rounded and gentle looking.
By kay on 04.18.2011
The windows glinted in the light. Barely able to be seen through, the little boys ducked their heads to see past their reflections to view the newest shipment of guitars. Bradson. Homemade. They were every musician’s dream.
By Sarah URL on 04.18.2011
don’t think just say. say it all say it loud. let it ring out against the walls, against it all. unburdened unbearing. everyone can hear just your voice, no additives. just listen. listen hard. it’s raw as ever. raw as anything. your voice.,
By Alyssa on 04.18.2011
I love acoustics. they make you listen to the world of sound in all its detail
By Raymondo URL on 04.18.2011
the sound of your voice thins as it moves over the broad green lawn
and as we step into the thick shadows of wood
our voices step closer, too
By angelofmercy URL on 04.18.2011
Acoustic reverberations twanged and banged through the ceiling which shook visibly and I wondered if the train would just come crashing through or perhaps just pass by, either way I was just far too tired in this grey hour to listen to the judder of the wheels at this time of weekend before my morning coffee or twenty.
By Phone's Off The Hook URL on 04.18.2011
Theturqoise walls seemed to open up the room, with the light flowing in and the yellow lace curtains swinging. From out the window came sounds, several sounds — the monotone whoosh of the breeze, the swish of long grass, and the sound of someone singing along with an acoustic guitar.
By Mildred URL on 04.18.2011
I want to learn how to play guitar. It’s one of the few instruments that I can’t play. And GOD. I love the sound of a great acoustic guitar cover. Every time I picture my perfect boyfriend, I imagine him playing me fabulous love songs on his trusty guitar. Guys are sooo sexy when they play.
By Tory URL on 04.18.2011
The acoustics above roared down and the ceiling visibly shook and I thought that in a crazy moment the train may just come hurtling through although it was quite obviously not a train but just a sound or some sounds from an early neighbour busying about in their routine but my head was sleepy and I pulled the eye mask back on over my half dream now populated with noise.
“SHUT UP,” Jamie yelled.
Leo just shrugged, looking down, shamed.
Jamie picked up the guitar from the ground and started dragging it back outside. The sound of her shout still reverberated around the room.
By Sophie Calhoun on 04.18.2011
Myles came up the creaking basement stairs with a acoustic guitar in his hands the Sunday before Bridget disappeared for a week. I told him over and over again that I didn’t know how to play, but he continued to ask every night before bed until I finally agreed. The strings were stiff and the sound was slightly dulled, but he couldn’t have been more pleased.
By Veerin URL on 04.18.2011
The music is echoing, yet I can barely hear it. All I’m seeing, all I’m feeling, are the words you’re singing. You’re not aware, but every word is a message straight to my heart, and every time you pluck a string I fall for you all over again.
By Emily URL on 04.18.2011
music. guitars. i love music. it is a giant part of my life. half my summer is around music. and a large part of my life. band, iPod, everything. it’s a passion. music can improve my mood or make me cry. i love acoustic music, it’s beautiful.
By katie URL on 04.18.2011
its a sound its a feeling its a way of being. its no fuss, theres no extra electric feel added to it, its pure and its real. when you need to unplug and get a sense of what real life is about again its what can take you to that place. that peace of mind.
By dededd on 04.18.2011
a division of Identity Crisis, Inc.