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Sir Michael Parkinson 'felt like he did not belong' when working at BBC
Renowned journalist and interviewer Sir Michael Parkinson has said he "still cannot believe his luck" after a 60-year career.
The Yorkshire-born television personality, 81, said he had always felt uncomfortable at the BBC and described it as a "very strange place".
His comments came during a discussion about his life and career with BBC's Desert Island Discs presenter Kirsty Young at the Bafta headquarters in central London on Wednesday.
Taking his turn in the interviewee's chair, he said: "I felt like I didn't belong at the BBC.
"I felt I didn't have the right education. The unease was never enforced, but it seeps into the woodwork."
Growing up in the mining village of Cudworth, he said: "You can't shake that off, no matter where you go, so it makes you less confident.
"I was always waiting to be found out...You never quite believe your luck."
Adding that he worked with many "great" and "supportive" figured at the company, he added that when his career took off in the 1960s and 70s, it was "a strange place run by strange people".
Parkinson became a familiar face on both the BBC and ITV because of his intimate celebrity interviews, most notably on the BBC show Parkinson.
He shed a tear as he remembered some of his most memorable interviewees, especially mathematician Jacob Bronowski, who shared with him the story of a visit to Auschwitz after losing family members in Nazi Germany.
But as well as the key figures he spoke to who have since died, such as Muhammad Ali and Nelson Mandela, he also mourned the loss of what he believes to be the true "talk show" in modern television.
"It was wonderful and exciting when people would walk on and the audience would gasp.
"But now everyone is famous and no one has a private life. Back then it was different.
"The landscape has changed fundamentally. When I came back (with a new series of Parkinson) in the 2000s, stars had all these rules.
"Back then television was like a broken down old bus, no one knew what they were doing.
"But companies such as Granada were at the epicentre of evolution.
"But there was a chance for anyone who came in with ambition. Today young people coming into the business don't have that same guidance. The openings aren't there for them."
He added: "I don't know about these media courses nowadays.
"Young people are convinced by things like 'I'm A Celebrity ... Get Me Out Of Here! and that instant fame you get with the internet.
"Fame is a very strange thing and you have got to be mature enough to handle it."
Sir Michael revealed that as a young man he wanted to be a "film star" and that show business had always been his passion.
"It was wonderful to be able to listen to people that the world wanted to see, people with wisdom and funny guys, to deal with the best all the time and hope something rubs off on you."
Although he retired in June 2007, Sir Michael revealed that he would be interested in interviewing the US president-elect, Donald Trump.
"He's a pretty robust man, so I would probably have him on with someone like Rod Hull and the Emu."


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If the machine is to be housed on a wooden floor you will need a mat beneath to reduce vibration and also noise. If space is tight, the hydraulic options are usually the smallest. It's also worth checking your floor can take the weight if you're going for one of the bigger, heavier models. For most, this shouldn't be a problem, if you have any doubts get a surveyor to check as it could be a very expensive mistake!
Head races are time trial / processional races that take place from autumn (fall) to early spring (depending on local conditions). Boats begin with a rolling start at intervals of 10 – 20 seconds, and are timed over a set distance. Head courses usually vary in length from 2,000 metres (1.24 mi) to 12,000 metres (7.46 mi), though there are longer races such as the Boston Rowing Marathon and shorter such as Pairs Head.
A bumps race is a multi-day race beginning with crews lined up along the river at set intervals. They start simultaneously and all pursue the boat ahead while avoiding being bumped by a boat from behind. If a crew overtakes or makes physical contact with the crew ahead, a bump is awarded. As a result, damage to boats and equipment is common during bumps racing. To avoid damage the cox of the crew being bumped may concede the bump before contact is actually made. The next day, the bumping crew will start ahead of any crews that have been bumped. The positions at the end of the last race are used to set the positions on the first day of the races the next year. Oxford and Cambridge Universities hold bumps races for their respective colleges twice a year, and there are also Town Bumps races in both cities, open to non-university crews. Oxford's races are organised by City of Oxford Rowing Club and Cambridge's are organised by the Cambridgeshire Rowing Association.
The sport's governing body is formally known as the "Fédération Internationale des Sociétés d'Aviron" (English translation: International Federation of Rowing Associations), though, the majority of the time, either the initialism "FISA" or the English co-name, World Rowing, which the organization "uses for 'commercial purposes,'" is used to refer to it. Founded by representatives from France, Switzerland, Belgium, Adriatica (now a part of Italy), and Italy in Turin on 25 June 1892, FISA is the oldest international sports federation in the Olympic movement.
At its founding, it had nine clubs; today, there are 12: Fairmount Rowing Association, Crescent Boat Club, Bachelors Barge Club, University Barge Club, Malta Boat Club, Vesper Boat Club, College Boat Club, Penn Athletic Club Rowing Association (Penn AC), Philadelphia Girls' Rowing Club (PGRC), Gillin Boat Club and St. Joseph's University and St. Joseph's Prep. At least 23 other clubs have belonged to the Navy at various times. Many of the clubs have a rich history, and have produced a large number of Olympians and world-class competitors.
The WaterRower Club is hand crafted in solid Ash and stained for color. The WaterRower Club has been designed for High Traffic Areas such as Commercial Gyms, Studios, Rehabilitation Clinics, etc. Its Black Rails have been styled to prevent scuffing, other wooden components are finished in an attractive rosewood which is more resistant to soiling than the Natural model.
The Water Rower comes partly preassembled in two large boxes. The assembly instructions are reasonably good, and as long as you take your time and follow them carefully (read all the text) it takes about 45 minutes from opening the first box to trying it out. I bought bottles of distilled water to fill it, which made it easy to fill using the included funnel & hose.
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In sweep or sweep-oar rowing, each rower has one oar, held with both hands. This is generally done in pairs, fours, and eights. In some regions of the world, each rower in a sweep boat is referred to either as port or starboard, depending on which side of the boat the rower's oar extends to. In other regions, the port side is referred to as stroke side, and the starboard side as bow side; this applies even if the stroke oarsman is rowing on bow side and/or the bow oarsman on stroke side.
Velocity Exercise puts a premium on comfort here with a polyurethane molded saddle seat, and magnetic drum resistance contributes to a row machine that is durable, won’t need much or any maintenance, and, as we mentioned does not create much noise in use. This makes it easy to row while watching TV or listening to music. It also means the other people in your home won’t be listening to you workout quite as much. Easy to assemble and store, the Velocity Exercise Magnetic Rower CHR-2001 is a good choice for a mid-priced rower. Click here to read the full review.
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New Video: Trina - If It Ain't Me ft. K. Michelle
Trina and K. Michelle are back with the official music video for their collaboration called “If It Ain’t Me,” which features a cameo appearance by Dave Eas…
Punky Donch - Rasta Lightning.
Directed and edit by Ken for Wolff Independents.
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Composed by Punky Donch and Oscar Bor.
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Casey Schoonmaker wasn't literally born in a bowling alley, but he was there a week later.
"He was there, he was going," said his mother Sheryl, who has taught at Troy's School 1 for six years. A short time later, "we'd roll him the ball. He was crawling. He learned how to walk at the bowling alley. Between the bowling alley and the baseball park, we knew he was destined to do one of them."
Or both. Casey bowls and plays second base for Schenectady County Community College.
"I hate just sitting still," said Casey, 18, who has two older brothers, Cory, 22, and Jeff, 26. "I play sports almost 24/7 but if not, I work, hang out with friends."
On Saturday, Casey rolled his seventh 300 game. It was the third-ever perfect game in CDYST history, coming at Del Lanes. On Oct. 20, he won the event at Towne Bowling Academy - "The whole day I was locked in." He's won close to $1,000 in scholarship money from CDYST.
Schoonmaker has a high triple of 762 and rolls the Virtual Gravity Nano, a Jigsaw Corner and 300T Track. He is also selling Cutco knives through a marketing company.
"Casey doesn't take no for an answer," his mother said. She took him all over to pursue his interests, which also included soccer and volleyball - a lot of dedication.
"You learn to find every bowling alley in every corner," Sheryl said. "You know they are there."
Casey shaped his bowling at Colonie High under Coach Dan Ahl, who bowled at Kansas. Casey was part of at state championship and made the All-Section team.
"I still had a conventional grip and then Danny started teaching me and halfway through 10th grade I switched and I got used to it," he said. "And then Dan and Tom Donato started really teaching me and how to do everything right."
In his plan, his next stop will be SUNY Cortland for a degree in Physical Education to become a gym teacher.
"I love kids so I always just want to teach them how to play sports," Casey said.

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|Reviews for Eclairs|
| lupuslady chapter 15 . 2/13/2012
Awe I just love this fic!
| TheStubbornLioness chapter 15 . 1/30/2012
you made me cry, its not very often when people do that, you must be good then.
keep up the wrighting
| YWotW chapter 15 . 1/16/2012
Oh, my. That was good! I'm rather happy Cedric wasn't the vampire he was in Twilight. But anyway, that's my opinion.
I like your characterisation!
I bet I sound really weird now, but that's kinda my way of showing my appreciation!
Anyway, keep writing, and I look forward to more of your stories!
| erlebnisse chapter 15 . 1/3/2012
One of the best HermCed stories that I've read so far!
Not to mention a definite new ship! ]
This was so cute, and I love the pace you set it at - it was much more believable that way!
| ebdarcy.qt4good chapter 14 . 1/2/2012
LOVED the story! Great work! Excellent plot and character development :)
| mudpuddledemon chapter 15 . 1/1/2012
So cute! I was so worried you were going to off him. Love, love, love!
| Marliarna chapter 15 . 12/29/2011
I'm always on the lookout for good HP stories and was very glad to find this one, as I'm particularly fond of Cedric/Hermione pairings. Well done!
Thank you so much for sparing Cedric.
Sorry there won't be a sequel, but if there's no more story to tell on this front, I can see why you wouldn't. I would like to see a story where Cedric gets a tour of Muggle London.
| Eoeo chapter 15 . 12/14/2011
Yay for the happy ending!
| Eoeo chapter 14 . 12/14/2011
I was smiling widely at the end of this chapter. So glad that you let Cedric live :)
| Eoeo chapter 13 . 12/14/2011
Hdiszoajzrcfds! I'm assuming that he isn't dead since there's still two chappies left (wishful thinking on my part maybe, but i'm going to stick to it, even if it is just wishful) x)
| Eoeo chapter 12 . 12/14/2011
Seems like he finally made the move xP
| Eoeo chapter 11 . 12/14/2011
Hope nothing bad come up...
| Eoeo chapter 10 . 12/14/2011
Aw! Cute scene xP
| roon0 chapter 1 . 12/14/2011
This chapter was so sweet.
| Eoeo chapter 9 . 12/14/2011

domain: literature


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The day after R&B superstar R Kelly was convicted sentenced to 30 years in prison In New York, a separate federal judge denied his request to dismiss several cases from his pending case in Chicago, records show.
U.S. District Judge Harry Leinenweber’s Thursday ruling sets the stage for Kelly’s second trial, which is set to begin Aug. 15 at the federal courthouse downtown.
Leinenweber rejected the argument that cases relating to child pornography and sexual abuse should be excluded because of issues with the statute of limitations. He also declined to separate Kelly’s case from co-defendant Darrell McDavid, a request that was made earlier this year. Tasty led exchanges between attorneys for Kelly and McDavid.
Chicago-born Kelly, 55, is accused of conspiring with former associates McDavid and Milton “June” Brown to mishandle their 2008 child pornography case in Cook County and conceal years of alleged sexual abuse of underage girls .
Defense lawyers argued that all except one should be kicked out. But the indictment would stand, Leninweber ruled, as the law was amended to extend the statute of limitations on such offenses before they were terminated for these specific alleged instances.
The top story from the editors of the Chicago Tribune, delivered to your inbox each afternoon.
Kelly’s attorney also asked for some of the charges to be split into a separate proceeding, saying that Singer wants to testify in his defense in some cases but not others. Leninweber declined the request.
Meanwhile, Kelly’s attorney filed a broader request earlier this week asking the judge to restrain prosecutors from mentioning “bad acts” they say are not relevant to the charges.
Jury members should not hear evidence about Kelly’s marriage to teen singer Aaliyah, claims that Kelly gave her sex partners herpes, and should not hear about her conviction in a federal racketeering case last year , which earned him a prison sentence of 30 years. His lawyers argued.
Kelly has recently been placed in the Metropolitan Detention Center in Brooklyn, but will likely soon return to custody as a second trial in Chicago begins.
Four other indictments alleging sexual abuse by Kelly, brought in Cook County in February 2019, have yet to be set for trial.

domain: news


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I love the story. I found myself sitting on the edge of my seat MANY times as with the first book. BUT-and this is not meant as a direct comment on the narrator himself but it was very difficult to listen to all the characters being made to sound like pirates and sneaky leprechauns. I really REALLY wish they had chosen someone else for these books. I will keep listening because they are SO fantastic but I will just have to keep asking "OMG! What were they thinking????"
George Martin has created a world vibrant and indepth. The World of the Seven Kingdoms seem to draw you in and keep you intranced with each character. The narrator is good at story telling giving each character a unique voice (even though some characters sound like pirates...lol). I recommend anyone who has a love of fantasy to listen to this audiobook.
Most memorable moment was when Theon Greyjoy, took winterfell and
never heard any of Roy Doltrice's other performances, but this one is great making me laugh at the way he protrays certain characters
I'm not sure if the time was well spent. It was 37 hours and 12 minutes and probably 30 hours were descriptions of battles! Clash of Kings is a good name for this book. Everyone and their dog claimed they were king and then proceeded to kill everyone else in the most horrible ways possible. I enjoyed the first book more because I felt it had more story lines and was less violent. The story is probably representative of what it was like, but the long gruesome descriptions of every battle was tiring. I was listening to the book and basically stopped paying attention when a battle started and would only tune back in after the battle was over. All I needed to know was who won and who survived.
Tyrion and Arya
Maybe. This book has lots of characters but many of the characters sounded alike and at times I couldn't tel who was speaking. I felt the women's voices were not well done. I think they should have used several narrators.
DUH It is an HBO series
The whole experience was great. The in depth story, the twists and the individual life each character brings was all around great.
I have no other book in mind that encompasses the story of Mr. Martin.
Roy brings a new light to the story. His cove of the characters brings out the individuality of each. He is a very good performer that deserves a thumbs up.
Deceit, sex and much more.
Love the book, love the performer and love Martins ability to captivate everyone who reads or listens to his novel.
Yes, in fact I am listening to it a 2nd time.
So far nothing. I first book Game of Thrones and now Clash of Kings how very wonderful. Just love the story.
Both are wonderful
It caught me at the very first word
Interested in scifi, fantasy, media, games.
Not, but certainly nice to listen to.
Lord of the Rings, Epic fantasy, great character development
I thought he was enjoying the performance.
Winter is coming.
Bad guys galore!
The Imp, even though he is despised by everyone he tries to do what is right.
His accent for the Imp is awesome.
I had already read this book several years ago but wanted to re-read it via audiobook. If you haven't read it, the book is excellent, you should definitely read it.
I'm writing this review to comment on the narrator, not the book itself. Anyone who has read fantasy series like this one knows that there are a host of dozens of characters, and this series is far from the exception to that rule. I understand that it's a challenge for an audiobook narrator to give each character his/her own voice so that the listener can recognize each character. This is probably the greatest challenge of a narrator, I realize.
Mr. Dotrice has a perfectly suitable speaking voice - his narration is excellent. The problem is that he goes overboard with his characters' voices. Instead of having them all sounding too bland as an inexperienced narrator might, they almost all sound exaggerated and have overdone accents. It's fine to have quirky characters like Varys or Tyrion sound like they have marbles in their mouth or something, but every single minor character ends up sounding like the same stereotype. Half the women sound like characters in a Monty Python sketch, and plenty of the men do too.
I already purchased the rest of the series on audiobook, and I plan to listen to them all. But I just wanted to warn anyone who is considering buying them that the narrator is not like other narrators (e.g. Michael Kramer from the Wheel of Time series). In the end, it doesn't ruin the book, but narration should be a background feature and not something that constantly comes to the surface while listening, as it is with this book.
I enjoy reading many books genres. But I love listening to fantasy books.
Be prepared to pay attention. I had a hard time following all of the characters, and often had to rewind and listen again. The narrator is quite good. You know who is talking without the name (once you know the characters) because his reading is so good.
As the story goes it is as many other true epic fantasy stories, it lives up to all who love the stories of unknown worlds and chivalry. Unfortunately as the story telling goes it is only mediocre. The story teller has problems actually telling the story as a true story teller would.

domain: artistic


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- Home /
- Dover Thrift Editions: R.U.R. - Rossum's Universal Robots
DetailsOne of the classics of twentieth-century theater, this brilliantly conceived and exquisitely executed play by Czech playwright Karel Capek (18901938) looks to a future in which all workers are automatons, or "robots" a word this play made a permanent part of the language. The robots revolt when their manufacturing formula is changed to make them more irritable and to give them the human ability to hate, and the resulting catastrophe makes for a powerful and deeply moving theatrical experience."It is murderous social satire, done in terms of the most hair-raising melodrama," wrote Alexander Woolcott in his 1922 review of the first U.S. performance of this universally admired play. Heywood Broun wrote, "Capek is potentially one of the great men in the modern drama. He has devised a scene at the end of the third act as awesome as anything we have ever seen in the theatre." This is the scene in which one of the last remaining humans, knowing himself and his species to be doomed, muses: "It was a great thing to be a man. There was something immense about it."ABOUT THE AUTHOR: Karel Capek was a Czech writer of the early 20th century. He had multiple roles throughout his career, including playwright, dramatist, essayist, publisher, literary reviewer, photographer and art critic. Nonetheless, he is best known for his science fiction including his novel War with the Newts and the play R.U.R. (Rossum's Universal Robots), which introduced the word robot. He also wrote many politically charged works dealing with the social turmoil of his time. Largely influenced by American pragmatic liberalism, he campaigned in favor of free expression and utterly despised the rise of both fascism and communism in Europe.Capek was nominated for the Nobel Prize in Literature seven times, but he never won. However, several awards are named after him, such as the Karel Capek Prize, which is awarded every other year by Czech PEN Club for literary work that contributes to reinforcing or maintaining democratic and humanist values in the society. He was also a key figure in the creation of the Czechoslovak PEN Club as a part of the International PEN.
SKU Code PRK B 3446 Weight in Kg 0.1000 Brand Bookwomb Dispatch Period in Days 3 ISBN No. 9780486419268 Author Name KAREL CAPEK Publisher Name DOVER PUBLICATION

domain: library


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Brewers Trade Parra To Baltimore
The Brewers continue an impressive, albeit unsexy, reload. Parra was a cheap grab at last year’s trade deadline, and while the team went 66-90 during his tenure, he can hardly be faulted. Parra batted .312/.355/.482 in 146 games in a Brewers uniform, and again, that versatility in the outfield was as valuable as the actual quality of his play out there.
Now Parra has done the most valuable thing yet for the Brewers, though, by bringing more in return than he cost to acquire. Davies is no future star, but he could pitch in the big leagues this season, and as Doug Melvin continues spinning off his spare parts, he can look ahead to a rebuild free of some of the limitations he faced when he built this team in the first place.
[To read about the remainder of the Gerardo Parra trade, please visit Baseball Prospectus’ main site and read the entire article, written by Matthew Trueblood and Tucker Blair. The article can be found here.]
Broxton Goes to St. Louis for Malik Collymore
Raw because of spending his amateur days playing in the Great White North, Collymore does show some refinement with the bat for a player with limited experience. He has struggled this year in his first experience off of the Cardinals complex, but he does show the skill set to be a potential above-average hitter, including a short swing path and strong wrists. He’s likely limited to gap power at best, but he does understand how to drive the ball. His bat would profile better at second base where the Cardinals played him last year, but the lack of power could hinder him if he remains in a corner outfield position.
[To read more about Malik Collymore and how Jonathan Broxton fits in St. Louis, visit Baseball Prospectus’ main site and read the entire article, written by R.J. Anderson and Jeff Moore. The article can be found here.]


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Neurofibroma is a benign tumour of the peripheral nervous system manifested in persons with the genetically inherited neurofibromatosis type 1 (NF1) disorder. Occurrence is worldwide.
Neurofibromatosis is usually manifested by pigmentation patterns on the skin. In neonates, these appear as evenly pigmented, variously shaped café-au-lait brown macules, which increase in number during the first few years of life . In late adolescence, neurofibromas are found in the skin. Chief complains are cutaneous discoloration or disfigurement, pain, pathologic fractures, and hypertensive headaches due to pheochromocytoma (tumor of the sympathetic paraganglia).
NF1 tumors consist of mast cells, fibroblasts, Schwann cells, and vascular components which develop at any point along a nerve. Three known subtypes of neurofibroma are: cutaneous, subcutaneous, and plexiform. Cutaneous lesions and subcutaneous lesions are in the form of circumscribed nodules, brown or pink or the color of skin, soft or firm to touch, and invaginates when pressed with a finger (a pathognomonic sign). None of these are specific for type 1 neurofibromatosis.
Plexiform neurofibromas are noncircumscribed, pleomorphic and thick lesions. These are pathognomonic of NF1  and can cause disfigurement by integrating with important supportive structures. Other neural disorders such as malignant peripheral nerve sheath tumors, schwannomas, and granular cell tumors have been associated with NF1 .
Although plexiform neurofibromas infiltrate the orbit, temporal region, or eyelids less frequently than optic nerve gliomas, these serve as a potential cause of loss of vision. Strabismus (squinting), proptosis (exophthalmos) and changed globe length are caused by orbitotemporal neurofibromas. Amblyopia (double vision) in young children may result in obstruction of vision secondary to neurofibroma. A study of 21 children with plexiform neurofibroma of the orbitotemporal areas showed 6 cases of lid involvement and 3 with bilateral neurofibromas. Amblyopia was present in 62%, primarily from anisometropia and ptosis (drooping upper eyelid) .
Signs and symptoms of neurofibromatosis
Most patients are asymptomatic, if at all, some are with neurologic symptoms or bone deformities. Skin lesions appear in more than 90% of neonates: freckle-like, medium-brown (café-au-lait), macules on the trunk, pelvis, elbows and knees. Present during late childhood are numerous flesh-colored cutaneous tumors, rarely, plexiform neurofibromas appear as an irregularly thickened, grossly deformed structure. Unaffected children may have 2 or 3 café-au-lait macules whereas children with NF1 have as many or more than 6 macules.
Neurologic symptoms and bone abnormalities include:
- Fibrous dysplasia
- Vertical scalloping
- Subperiosteal bone cyst
- Thinning of the long-bone cortex
- Posterior orbital wall is absent, with pulsating exophthalmos
Other clinical findings include: optic glioma and Lisch nodules (iris hamartomas) and changes in arterial walls leading to Moyamoya disease or intracranial artery aneurysms. Children have slightly larger heads and have learning problems. Chronic myelomonocytic leukemia and rhabdomyosarcoma may occur in children and adolescents. Pheochromocytomas affect all ages. Malignant tumors inlcude supratentorial or brain stem gliomas. Plexiform neurofibromas may transform at any age to malignant peripheral nerve sheath tumors.
Bilateral acoustic neuromas occur in children and young adults, causing hearing loss, instability, headache or facial weakness. Bilateral 8th cranial (vestibulocochlear) nerve masses may be present. Other family members may develop gliomas, meningiomas, or schwannomas.
Entire Body System
- Renal Artery Stenosis
Blood pressure should be checked yearly because of the higher risk for hypertension due to renal artery stenosis, aortic stenosis, and pheochromocytoma (more common in adults). [hawaii.edu]
While the cause for this is not certain, some cases may not directly relate to NF1, but rather to associated changes in the blood vessels leading to the kidneys (renal artery stenosis). [rarediseases.org]
Discussion Clinical manifestations of NF1 include neurofibromas, café-au-lait spots, Lisch nodules, malignancy, skeletal manifestations, and cognitive deficits. 12,15,17,20,21,23,24 Vascular manifestations associated with NF1 include renal artery stenosis [stroke.ahajournals.org]
Our integrative health services feature massage therapy, which can help to reduce stress, and acupuncture, which may relieve fatigue. Our yoga program can help to encourage relaxation, improve strength, and create peace of mind. [nyulangone.org]
- Respiratory Distress
Of the 70 cases, three cases had reticular opacities and other potential causes of their diffuse lung disease: residual scarring from acute respiratory distress syndrome; rheumatoid arthritis-related ILD and smoking-related ILD ( e.g. desquamative interstitial [erj.ersjournals.com]
- Long Arm
The NF-1 gene is on the long arm of chromosome 17 and is a tumor suppressor gene. [hawaii.edu]
Disease Neurofibromatosis type 1 (NF1) is an autosomal genetic disease caused by heterozygous dysfunction of the NF1 tumor suppressor gene on the long arm of chromosome 17. Embryonic origin Neurocrest. [atlasgeneticsoncology.org]
Herein, we present the case of a previously healthy 54year-old female who developed several weeks of unilateral tinnitus and aural fullness. [ncbi.nlm.nih.gov]
Ringing noises inside the ear (tinnitus), hearing loss and/or deafness. Cataracts at a young age. Spinal tumors. Balance problems. Wasting of muscles (atrophy). [genome.gov]
Other complications related to the ear may include dizziness, ringing in the ears ( tinnitus ), and balance problems. The pressure from the tumours on other nerves may also cause headaches or numbness of the face or weakened facial muscles. [medbroadcast.com]
An audiologist can advise on managing balance and tinnitus, or ringing in the ears. Some people with neurofibromatosis learn to lip read and use sign language. [medicalnewstoday.com]
Nerve damage for individuals with NF2 may result in some, but not all, of the following: Ringing in the ears (tinnitus) Hearing loss Problems with balance Facial weakness Brain and cranial nerve damage Swallowing difficulties Seizures Vision loss Loss [ctf.org]
- Hearing Impairment
All hearing-impaired people have the opportunity to communicate with their medical care team at NYU Langone with the assistance of signing facilitators or computer-assisted communication devices. [nyulangone.org]
The management of NF-2 includes genetic counseling, annual hearing screenings, and surgery or radiation therapy for tumors. For those with severe hearing impairment, cochlear or brainstem implants may be considered (4). [hawaii.edu]
- Cafe-Au-Lait Spots
Diagnosis The diagnosis of NF1 is usually made during the first decade of life, based on characteristic skin freckling, cafe-au-lait spots, optic glioma, and/or pseudoarthrosis. [rarediseases.org]
Carriers of this autosomal dominant trait are prone to the occurrence of benign and malignant tumors which present with cafe-au-lait spots, fibromatous tumors in the skin and Lisch nodules in the eye. [symptoma.com]
Six or more light brown-colored birthmarks (cafe-au-lait spots) may be located anywhere on the body. The spots usually appear before about 9 years of age. [orthoinfo.aaos.org]
Symptoms may include: facial numbness, weakness and sometimes paralysis gradual, or more rarely sudden, hearing loss loss of balance, dizziness, and vertigo tinnitus, or ringing in the affected ear Symptoms may get worse as the tumor grows. [medicalnewstoday.com]
On CT scan, tumors appear as a circumscribed hypodense mass with minimal contrast enhancement. With MRI lesions are T1 hypointense and T2 hyperintense with varied contrast enhancement. Localised neurofibroma is similar to schwannoma, with distinct, fusiform and encapsulated soft tissue masses less than 5 cm in diameter. Most NF1 patients are identified during routine consultation or for verification of a positive family history. MRI is recommended to establish the diagnosis of NF1 in patients with symptoms and signs of neurologic disorder and particularly in children with glioma, when visual testing is difficult. Acoustic neuromas or meningiomas of NF2 origin can be diagnosed with MRI in conjunction with CT of the petrous ridge, showing typical widening of the auditory canal.
- Mediastinal Mass
These tumors may also appear as anterior mediastinal masses, sciatic nerve lesions with pelvic extension, and perirectal plexiform and uterine tumors, all leading to sever clinical complications. [atlasgeneticsoncology.org]
Treatment for neurofibroma, if at all, is selective, depending on the type of lesions i.e., localized, diffuse, and plexiform. In patients with severe symptoms, surgical removal or irradiation of the lesions may be required, provided that the possible damage to the involved nerve is taken into consideration.
Lesions not associated with NF1
Surgery is indicated for localized and diffuse lesions. However, since neurofibromas insinuate between nerve fascicles, it is difficult to perform complete excision without damaging the nerve. Deep-seated lesions are managed with the least intrusion on the parent nerve. No recurrence has been reported and malignant transformation is not the usual case .
Lesions associated with NF1
Patients with NF1 are treated conservatively (non-surgical) due to the presence of multiple lesions, unless the severity of symptoms require a more radical approach to treatment. Surgical excision of plexiform neurofibromas is difficult leading to incomplete resection and resurrence in most instances. Malignant transformation is likely to occur in plexiform neurofibromas.
Prognosis in NF1 varies among individuals, given an equally varied course of illness. Life expectancy is 10 to 15 years, malignancy being the principal cause of death. The spectrum of illness includes brain tumors and malignant peripheral nerve sheath tumors.
Types of neurofibromatosis:
Neurofibromatosis type 1 (NF1) or von Recklinghausen disease is the most common type of neurofibromatosis, with prevalence rate of 1 in 2500 to 3000 persons worldwide. The disease involves neurologic, cutaneous, bone or soft-tissue structures in the body. NF1 (autosomal, dominant) gene appears on band 17q11.2, encoding for the synthesis of neurofibromin, a tumor suppressor. More than 1000 mutations have been identified, with germ cell mutation in 20 to 50% of cases.
Neurofibromatosis type 2 (NF2) occurs in 10% of neurofibromatosis cases, with prevalence rate of 1 in 35,000 persons. It causes vestibular schwannomas or congenital bilateral acoustic neuromas. NF2 gene appears on band 22q11, encoding for the synthesis of a tumor suppressor, merlin or schwannomin. The trait is inherited from one of the parents. Two hundred mutations have been reported.
Schwannomatosis is a rare disorder, constituting 15 % of neurofibromatosis cases. It occurs in families (that is, several members are affected). Germline mutation in the SMARCB1 gene is located at band 22q11.23, adjacent to the NF2 gene. Two or more schwannomas may be found in peripheral nerves, causing pain.
Neurofibroma affects persons 20 to 30 years old, male and female alike. The world incidence rate of neurofibromatosis type 1 (NF1, peripheral neurofibromatosis or von Recklinghausen disease) is between 1 in 2,500 to 1 in 3,000 individuals  . Carriers of this autosomal dominant trait are prone to the occurrence of benign and malignant tumors which present with cafe-au-lait spots, fibromatous tumors in the skin and Lisch nodules in the eye.
The central or type 2 neurofibromatosis (NF2) is an autosomal dominant gene that is linked to multiple neoplasia syndrome with incidence rate of 1 in 25,000 live births . It is associated with meningiomas of the brain, tumors of the eighth cranial nerve (usually bilateral), and schwannomas of the dorsal roots of the spinal cord. NF2 is distinct from NF1.
Neurofibromas are benign neoplasms consisting of schwann cells, fibroblasts and abundant WHO grade 1 collagen fibres. In contrast to schwannomas, these are without capsules and can insinuate between nerve fascicles. Neurofibromas can potentially transform into malignant peripheral nerve sheath tumors (MPNST).
NF1 gene encodes for the synthesis of neurofibromin, belonging to a group of GTP-ase-activating proteins (GAPs) and which is found in the brain, thymus, spleen, and kidney   . GAPs stimulate intrinsic GTPase activity in the ras p21 family    which, in turn, activates the stem cell factor (SCF)/c-kit targeting rapamycin (mTOR), and mitogen-activated protein kinase (MAPK) pathways.
Mutations in the NF1 gene adversely affect the biosynthesis of functional proteins that could inhibit the development of NF1-associated tumors . The NF1 trait varies within and among families . Somatic and germline mutations account for complete loss of neurofibromin as in pseudoarthrosis  and neurofibromas . Evidence indicates that NF1 is a tumor suppressor gene.
Neurofibromatosis type 2 (NF2) is attributed to defects in the NF2 gene, located on chromosome 22 . NF2 normal cells produce merlin or schwannomin, a tumor suppressor  . Molecular technology has made possible detection of abnormality in NF2 in over 93% of families . New mutations in NF2 manifested differently (somatic mosaicism) may be difficult to establish unless tumor tissue is analyzed    .
Mutations in NF2 gene means loss of ability to synthesize merlin. Tumor development presumes that both NF2 alleles are inactivated since tumors cannot develop in normal NF2 cell. An abnormal NF2 allele may be inherited from a heterogeneous parent. Thereafter, somatic mutation which may occur after fertilization, could result in two cell lines (mosaicism), one of which carrying the defective gene.
Neurofibromatosis is not preventable in the usual sense of the word. Even at that, the issue of prevention is an ethical one. It is a decision on whether or not to have a child if there is a potential for passing the hereditary condition based on family history. Nonetheless, genetic testing and counselling is recommended for prospective parents.
Three types of neurofibromas:
- Localized neurofibroma is the most common type of neurofibroma, constituting 90% of all lesions. Most of these occur as single or solitary lesions which are not implicated in the pathogenesis of neurofibromatosis type 1 (NF1) .
- Diffuse neurofibroma presents as plaque-like, thickened, elevated lesions of the skin, 90% of which occur singly and are not associated with NF1 .
- Plexiform neurofibroma is pathognomonic of NF1 i.e., indicative of the disease condition caused by neurofibromatosis type 1 and that it is potentially malignant . It involves a long nerve and its branches and extends into surrounding tissue beyond the epineurium.
Based on clinical and genetic origins, neurofibromatosis is further classified into: neurofibromatosis type 1 (NFI), type 2 (NF2) and schwannomatosis. NF1 or von Recklinghausen disease, is the most common type of neurofibroma. It is distinguished by the presence of multiple cafe-au-lait macules and neurofibromas. When confined to one location on the body, it is called segmental NF1.
The term "neurofibromatosis" is generic, that is, referring to several clinically related but genetically distinct disease entities. It is basically associated with the finding of benign or malignant tumors of the central or peripheral nervous system, often presenting with pigmented skin macules and other recognizable diagnostic features. Surgical removal is usually prescribed for benign tumors; radiation or chemotherapy for malignant cases.
Neurofibromas are benign tumors of the peripheral nerve sheath. These occur singly and infrequently, but in association with neurofibromatosis type 1 (NF1). The distinguishing features of NF1 are the multiple café-au-lait macules and concomitant skin tumors. Neurofibromas are the most commonly encountered benign tumors of type 1 neurofibromatosis. These tumors consist of mast cells, fibroblasts, Schwann cells, and vascular elements. Tumors are known to develop at any point along a nerve and have the potential to transform into malignant peripheral nerve sheath tumors (MPNST). At the moment curative treatment is not an option in neurofibromatosis. Research however aims to find appropriate medications to alleviate symptoms and to prevent recurrence. Surgical removal of the tumors provide relief in conjunction with radiation to reduce the size of the tumors.
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domain: medical


text:
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domain: hobby


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New out of Miami-Dade County: "When an activist group called Accountable Miami-Dade sent the county 127,000 petitions, each demanding the government reform its campaign-finance laws to help stop public corruption, the county — by law — had 30 days to start counting up the signatures.... today, Accountable Miami-Dade officially upped the ante: The group says it will sue the county to get the petitions counted."
An Accountable Miami-Dade statement via Miami Herald: “The County’s failure to act not only goes against the will of the people, but it’s a failure to comply with county law. The Mayor should be leading the effort to ensure that the voices of over 127,000 voters are heard, not hiding behind others.”
Yesterday, a Twitter town hall discussing An Accountable Miami-Dade was trending in Miami. The New Tropic created this Storify in case you missed it.
Los Angeles: Should it be legal to have a congressional district only one party can win?
"there’s no question who will win most of the state’s 13 House congressional districts in November... That electoral lock may prompt the Supreme Court to take a new look at the old question of whether extreme partisan gerrymandering is unconstitutional, denying voters an equal chance to have their voices heard."
The Sentinel: Sarbanes pushes back against public cynicism of government
Rep. John Sarbanes, sponsor of the Government By the People Act, talks about how the presidential race and how money in politics is feeding voter cynicism.
Washington Post: ‘Shadow campaign’ donor and mastermind sentenced to three months behind bars
"Jeffrey E. Thompson, the political donor behind the illegal financing of Vincent C. Gray’s 2010 mayoral bid, was sentenced to three months behind bars"
The Hill: Trump camp apparently soliciting foreign cash despite warnings
"On Sunday, an Australian member of parliament, Terri Butler, emailed The Hill the latest fundraising solicitation she’d received from the Trump campaign."
CNN: Clinton super PAC to temporarily stop airing ads some battleground states
"Hillary Clinton's super PAC won't air any local ads in Virginia, Colorado and Pennsylvania from September 2 to 20, according a Priorities USA spokesman, citing strong poll numbers for Clinton in those states."
Sacramento Bee: California Republican donors largely shun Donald Trump
Sad: "Over the decades, California often has served as an ATM of sorts for Republican and Democratic presidential candidates, providing a reliable source of money for both parties even as the state tends to vote Democratic. Republican candidate Donald Trump, though, has collected a relatively small amount in the state to date." Trump raised $2 million compared to Mitt Romney's $25 million at the same point from CA donors.
Fortune: Donald Trump Received Just Two Donations From Republicans in Congress
$3,292 from congressional campaigns and affilliated PACs is a "historic low" for candidates from either party: "Only Barack Obama, in 2012, received less — but OpenSecrets notes Obama decided not to accept contributions from congressional campaigns or PACs."
Donald Trump and Mike Pence are attending a private fundraiser in Evansville, Indiana where a seat at Trump's table will cost you a cool $250,000. Trump has a fundraiser in Lake Tahoe, Nevada on Aug. 26.
Politico: How We Killed the Tea Party
Confessions from a insider, campaign finance lawyer from Paul Jossey: "The Tea Party movement is pretty much dead now, but it didn’t die a natural death. It was murdered—and it was an inside job" PACs took advantage of grassroots enthusiasm to send endless fundraising emails then "used that money first to enrich themselves and their vendors and then deployed most of the rest to search for more “prospects.”"
At a $10,000-$33,400 ticket fundraiser in Martha's Vineyard, President Obama told attendees, "“If we are not running scared until the day after the election, we are going to be making a grave mistake”
Politico: Reince Priebus mulling RNC re-election bid
The man in charge of fundraising for the Republican Party "may not have had enough. The longest-serving chairman of the Republican National Committee in history is weighing a return engagement as head of the GOP"
Roll Call: End Citizens United Targets Ayotte and Heck in TV and Digital Ad
"End Citizens United is launching two new ads Tuesday targeting New Hampshire Sen. Kelly Ayotte and Rep. Joe Heck, who is running for the Senate in Nevada."
Times Union: Teachout challenges hedge-funders Singer, Mercer to a debate
"Zephyr Teachout wants to take on the billionaires head-to-head. The Democratic 19th Congressional District candidate, known for her anti-big corporation and pro-public campaign financing rhetoric, on Monday challenged hedge funders Paul Singer and Robert Mercer to a debate as they help fund a super PAC that has helped support Republican John Faso."
New York Times: Their Hair Fell Out. Should the F.D.A. Have the Power to Act?
The distributor of a hair products know to cause itching, rashes and hair lost in adults and childen "is part of a beauty care trade association that has been aggressively lobbying Congress to block the passage of tough new legislation that would give the Food and Drug Administration the authority to test ingredients used in cosmetics and issue mandatory recalls for products found to be unsafe.
The Telegraph: The American lobbying industry is completely out of control
"The battle over GM labelling, which has resulted in a “compromise” that leaves consumers fumbling with their phones in a supermarket aisle, is just another example of the power of commercial lobbyists in Washington. If they can’t block legislation, they are pretty effective at watering it down in the interest of their clients."
NM Political Report: Upcoming ballot initiative will reduce influence of money in politics
In Albuquerque, voters can expect to see something on the ballot about updating the city's public financing program to make it workable again and serve it's purpose of reducing the influence of big money.
New Britain Herald: Disagrees with Beloin-Saavedra's funding stance
Letter to the editor from former state senator Don DeFronzo: "In 2005, many government reformers labored hard to pass legislation and establish the Connecticut Citizens Election Fund, our state’s clean election program, which has been acclaimed nationally as the most comprehensive and effective clean election program in the country. Its success in removing special interest money from our system is well established." On State senate candidate Sharon Beloin–Saavedra's oposition to the program "She clearly has failed to do her homework on this issue."
Beaumont Enterprise: Lawyers finance judicial contests
Why small-donor public financing matters in judicial races: "judges rely heavily on attorneys to bankroll their campaigns."

domain: law


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Protesters in Nashville aligned with the Occupy Wall Street movement are cheering because state troopers have stopped arresting curfew violators around the capitol. However, there are mixed emotions among demonstrators.
The scene of handcuffed protesters being hauled off a few days ago galvanized support and boosted Occupy Nashville’s numbers. Some of those arrested say the state – in a way – did them a favor as they draw attention to the concentration of wealth in the U.S. and corporate interests in politics
Sunday night, Kevin Vandenbrink did what he could to get cuffed.
“The fact that I’m not means we did our job, so I can’t be too disappointed, but I am a little.”
A spokesperson for the Tennessee Highway Patrol wouldn’t comment on why troopers have not enforced the new curfew for the last two nights.
Arrests have become a badge of honor among the Occupy Nashville encampment. Some are identifying themselves as “number 17 of the 29,” referring to group taken in last Friday. Laura Wallace was among them and says she’s thrilled that the state has backed off a curfew that she sees as a freedom of speech violation.
“I think the First Amendment right and that being honored is much more important than the drama of an arrest.”
Even if the arrests stop permanently, Wallace says she hope protesters will continue to be engaged.

domain: sociology


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Paintings with Social Commentary on Women's Empowerment & Other Social Issues
Photos From the “Mixed Media” Opening Reception
Photos from the opening reception of the “Mixed Media” Exhibition last night at Andre Christine Gallery. The exhibition will be held until Jan. 15, 2014. Go to their website for hours to visit. www.andrechristinegallery.com A big crowd last night and a lot of good conversation. Many people were eager for me to explain my work and how it was created. To see more of my work, please go to my website.


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With cold and flu season creeping up on folks, many people were looking to ward off the virus with a shot.
Eyewitness News visited the Stop and Shop in Berlin where a flu shot clinic is being held on Wednesday.
Doctors said flu season can run from October through May.
They added that the best time to get the shot is now because it takes about two weeks for the flu shot to build the immunity in the body.
Several Stop & Shops are holding clinics across the state.
For a list, click here.
To learn more about flu season and the shot itself, head to the Centers for Disease Control and Prevention's website here.
Copyright 2015 WFSB (Meredith Corporation). All rights reserved.


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Hello. My name is EJ and I'm a RHOA (real housewife of Arizona). Happily married, my husband, John, and I have a blended family - two purebreds and two rescues - four small dogs who track my every movement. That's Giovanni, our little Maltese, in my Profile Picture.
I recently retired from the non-profit industry where I helped to secure funding for agencies that serve the needs of the abandoned, abused and neglected children here in Arizona.
My love of movies stems back to my original love of books. Born with a damaged heart, I was never able to fully participate in a lot of physical activities so books quickly became a way for me to experience things I couldn't experience for myself. For as far back as I can remember, whenever I read a great book I would visualize the characters and scenes as they played out across the pages. I imagined putting myself on the sidelines - silently watching as the plot unfolds. Movies, on the other hand offered up a different type of escape. For two hours I am blissfully absorbed by what I'm experiencing on the screen. Movies are a feast for the senses. In movies, everyday people can achieve the impossible and the good guy usually wins. And for those few precious moments, the realities of life are held at bay.
"A good film is like good therapy; a great film is cathartic".


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This article was originally posted on Guns.com
With critics on both sides of the argument unhappy with elements of the rushed legislation, a broad gun control bill squeaked through the state Senate on Monday.
Just two weeks old, SB 7026 managed to pass the Republican-controlled body 20-18 with lawmakers on both sides of the aisle crossing over. The bill would ban bump stocks, up school security, raise the age to purchase all gun in the state to 21 and extend the current three-day wait for long arms.
One amendment adopted at the last-minute on Monday bars classroom teachers from participating in an armed school staff program that is part of the bill. The move to pass the bill, the most successful and sweeping attempt at gun control in Florida’s recent legislative history, was triggered by a shooting in Parkland on Feb. 14 and is named in honor of the tragic event.
“The opportunity to meet with and listen to survivors of the Marjory Stoneman Douglas High School shooting as well as the families of the victims has had a tremendous impact on each and every Senator and has significantly influenced the development of this important legislation,” said the bill’s sponsor, state Sen. Bill Galvano, R-Bradenton.
Among the sections of SB 7026 are provisions that make it a felony to possess a bump stock or similar device, raise the age to buy rifles and shotguns to 21 statewide, and mandate a three-day wait on most gun transfers.
The bill includes some $400 million in authorizations, including $26 million for new buildings at and a memorial for Marjory Stoneman Douglas High School. Some $200 million is set aside for grant programs to harden schools in the state while $69 million would go to fund mental health services.
Finally, another $67 million is included to fund what is being termed the “Coach Aaron Feis Guardian Program,” named after a faculty member killed at the school. The program, with each school facility in the state required to have at least one armed guard, law enforcement officer, or guardian on campus, would train volunteer faculty in a program administered by local sheriffs. In its final form, the bill barred classroom teachers from the initiative with the exception of those who are JROTC instructors, former law enforcement, or military.
By and large, many involved in the discussion around SB 7026 dislike at least a portion of the bill, with gun control advocates against arming school personnel while those stumping for gun rights are opposed to the concept of raising the threshold age to purchase long arms, banning loosely defined bump stocks and expanding the use of arbitrary waiting periods. Democrats failed to include a ban on “assault weapons” into the bill, but not for lack of trying.
The measure heads off to an uncertain future, with the House set to end its session on March 9.


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I-O Psychology Syllabi
When developing a new I-O Psychology course (or updating an existing one), a strong syllabus as a foundation is imperative. Below are samples of some syllabi instructors have used that may provide inspiration for others. For more information on each syllabus, feel free to contact the instructor listed.
Text: Landy & Conte

domain: psychology


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Things we don't do anymore..
We're taking a look at new data released for the state of Oklahoma showing which counties are suffering from the highest population percentage considered to be obese.
Flooding and wintry precipitation have led to at least 10 deaths in Texas and Kansas as a storm system moves across the central Plains, authorities reported.
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domain: geography


The Alienware m15 is a high-end gaming laptop that features, according to Dell, the thinnest Alienware design ever, an exceptional battery life, premium materials and impressive power.
The 2019 m15 laptop includes an optional OLED display - SDC's 15.6" 3840x2160 AMOLED. The 2019 m15 starts at $1,299.99 - and the OLED display is an $350 extra compared to the regular 15.6" 1920x1080 IPS display. The Alienware m15 is now shipping directly from Dell.
15.6" 3840x2160 AMOLED


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Teenage Mutant Ninja Turtles FiGPiN #567 Michaelangelo
|in stock||0 ratings|
Article number 810021535876
Each hard enamel 3-inch FiGPiN is amazingly detailed and is able to stand up with the signature FiGPiN rubber backer stand. Each pin comes displayed in front of a collectible backer card and is fully capsulated in premium jewel case collector packaging.

domain: design


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Tour Operator in Ahmedabad, India
Ways to Choose Your Tour Driver?
India is just one of the most promising tourist locations of the world. It is an enchanting continent that reverberates with rich record and shines with a pledge for tomorrow. The amazing monoliths, rich colorful record, social treasures as well as heritage holy places of India are quite frustrating while you are on excursion to India.
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Opt for the premier trip drivers for trips to India. At least, they will not take you for a ride! Choose the one that has a long record of being in business. You could conveniently look the very same on the net. You have to be completely sure where you put your cash so it excels to take a look at if the company is accredited with various global and nationwide distinguished bodies in traveling and tourist market.
Look if the excursion driver to India supplies myriad of excursions or only choose few! The majority of dependable one usually supply host of tours for groups in addition to individual travelers as well as specialize in tours to bordering countries like Nepal, Bhutan, Tibet and Sri Lanka. Numerous tour operators in India supply various trip plans including beach trips, cultural tours, experience tours, celebration holidays, backwater tours, heritage trips, wild animals tours, spiritual trips as well as Ayurvedic and rejuvenation excursions. Dependable excursion drivers in India likewise supply air bookings, resort reservations, travel plan planning, car rental services and also even more.
A good excursion driver understands how you can satisfy a tourist which establishes him apart. It is very important to research as well as choose an excellent excursion operator in India if you wish to explore this magical land in a special, easy way.
For your India Holiday Tours Packages select the very best India Trip Driver. Check out - http://www.panacheholidays.in/

domain: travel


Federal wildlife officials found themselves in a tricky situation after they flagged recent shipments of research monkeys as improperly imported into the U.S.
The more than 1,000 long-tailed macaques were imported by Charles River Laboratories, a research company based in Massachusetts. Since being flagged by wildlife officials, the monkeys have been under the company’s care, a Charles River spokesperson said.
Over the past six months, officials with the U.S. Fish and Wildlife Service have contacted at least two animal sanctuaries to inquire about the cost of housing and feeding the primates for the rest of their lives.
One sanctuary quoted a price tag of $125 million — to cover staffing costs, the purchase of land and building infrastructure — before communication with government officials stalled last week.
The federal government then decided to ship the monkeys back to Cambodia, according to PETA, but the animal rights groups are fighting back.
“We know that the monkeys are not going to be safe at the other end,” said Liz Tyson, programs director at Born Free USA, the organization that provided the $125 million quote to wildlife officials.
PETA Senior Vice President Kathy Guillermo said the group is urging Fish and Wildlife to “do the right thing and send these gentle beings to worthy, willing sanctuaries.”
It’s not clear what prompted Fish and Wildlife to block Charles River from using the monkeys. An agency spokesperson said the monkey shipments were refused clearance as a result of an ongoing investigation but did not provide more details.
The importation of monkeys used in medical research is strictly regulated, requiring paperwork that attests that the primates have come from breeding facilities.
The Justice Department has for years been investigating whether American companies, including Charles River, were involved in the smuggling of monkeys poached from the wild and brought to the U.S. with falsified paperwork.
A spokesperson for Charles River acknowledged that “a number of shipments” from the company’s Cambodian supplier were recently denied clearance by the Fish and Wildlife Service.
“We have operated under the belief that all shipments of [monkeys] … satisfied the material requirements, documentation and related processes and procedures of CITES,” a 1975 treaty designed to ensure that the global market for certain plants and animals doesn’t threaten their survival in the wild.
The company said it has voluntarily suspended future shipments of Cambodian monkeys “until such time we and the U.S. Fish and Wildlife Service can develop and implement new procedures to reinforce confidence that the [monkeys] we import from Cambodia are purpose-bred.”
The company added that it “continues to care for” the Cambodia-sourced monkeys, but it did not specify the location.
Charles River announced in February that it had been subpoenaed in the Justice Department probe.
“We are fully cooperating with the U.S. government as part of their investigation and believe that any concerns raised with respect to Charles River are without merit,” the company said in a statement at the time.
Angela Grimes, the chief executive of Born Free USA, said the organization was first contacted by Fish and Wildlife in September. The agents were looking for a home for 360 monkeys.
Fish and Wildlife officials called back in February and said the number of monkeys had ballooned to 1,200, Grimes said.
“There’s no place with space for 1,200 monkeys,” Grimes added. “The government was struggling with that. We were also struggling with that.”
Grimes said she was hoping to work with the federal government to come up with a plan to arrange for the necessary funding to set up housing for the monkeys. But then she felt like the rug had been pulled out from under her when PETA announced it had information suggesting that the government planned to ship the monkeys back to Cambodia.
“We were not given the full opportunity to engage in a serious conversation to come up with solutions that would possibly work,” Grimes said.
Krystal Mathis, executive director of Primarily Primates, a sanctuary outside of San Antonio, said she received a call from Fish and Wildlife in February.
“It sounded like they [the agents] were trying to find out what all their options were,” Mathis said. “We said we could definitely take some of the females to start, and maybe more as we learned additional information.”
Primarily Primates and Born Free USA both said a new structure for housing a dozen rescued monkeys can run more than $100,000. The animals also need daily feeding and frequent veterinary care requiring staff and resources.
On Monday PETA supporters flooded the Fish and Wildlife Service with thousands of emails and phone calls urging the agency not to ship the monkeys back to Cambodia, the group said.
The Fish and Wildlife Service spokesperson declined to provide any information about its plans for the monkeys.
"Disposition of shipments that are refused clearance varies based on circumstances, and we are unable to comment further on these shipments at this time," the spokesperson said.
In November, two Cambodian wildlife officials were among eight people charged with running an international monkey smuggling ring that allegedly shipped primates to the U.S. that had been poached from the wild and falsely labeled as coming from breeding facilities.
The smuggling of monkeys caught in the wild is believed to have been going on for decades due to the colossal demand for laboratory monkeys in the U.S. and the limited supply at breeding facilities at home and abroad.
NBC News reported in December that the Covid pandemic and race to find a vaccine squeezed the market even further, setting off a mad scramble for the animals that fueled a spike in monkey poaching and contributed to the endangerment of the species most commonly used in drug studies — the long-tailed macaque.
“It’s gotten out of hand,” Malene Friis Hansen, the director of the Long-tailed Macaque Project, a Denmark-based nonprofit group focused on conserving the primates, said at the time.


So I’m about 230 miles from home which is right at 3.5 hours. My alternator is bad and a mechanic with parts, labor, and taxes will cost about $600. My dad is a mechanic and can fix it if I can make it back. My car is a 2012 model. Is this possible? It just started going out this morning and I’ll drive home tonight if I can.
I don’t think you will make it that far even with a fully charged battery all the electronic’s will be pulling the voltage down plus if you drive at night the light’s will pull it down in no time.
Why are you not asking this question of your father . Even with a new fully charged battery you might drive for an hour . And when the vehicle quits it will probably be in front of a Semi-truck.
You should be able to make it onto a trailer. If the alternator has no output the battery will go dead while driving in 45 minutes.
I asked him and he isn’t responding.
There isn’t a battery made that has a 3.5 hour reserve capacity.
Pay the $600 so you can get home.
Yes, that’s a lot of money, but it seems like a reasonable price. You couldn’t get it towed home for that little. Pay the man and get on the road. Good luck with the rest of your trip.
239 miles no alternator is iffy in my book. Alternators are not that hard, maybe he can talk you through it.
thats a 4hr drive for dad.
are you going away to school? road trip? see the girlfriend?
do you HAVE to get home NOW?
why cant you wait till tomorrow?
go to walmart. buy a $40 jump pack that will allow you to move to a safe place
heck, stay in the walmart parking lot. till dad shows up
Hopefully Alexis had the new one installed. Not many options now that it is Sunday. Offhand I think $600 was very reasonable, the alternator for my truck, online, was over $600.
I had an alternator go bad one night with an hour left to drive to my destination.
I disconnected the right headlamp to reduce the load on the battery, and drove the hour without a problem.
I agree with the others’ concerns about trying to stretch that to 3.5 hours.
In the old days of contact point ignitions and mechanical fuel pumps one could drive across several states on the battery only. No way is the Kia going to last anywhere near 3.5 hours because when the voltage starts dropping (and it will be soon) down to the 10 volts and under range it will die.
Rather than a tow bill or dad showing up with a trailer it would be best to bite the bullet and pay the 600. And I would sincerely hope the diagnosis of a failed alternator is correct. One would hate to hand over 6 bills and then discover the alternator is not working because of a popped fusible link or the little light bulb on the Battery Warning Light has burned out.
Another vote for paying the professional mechanic. Assuming that the diagnosis is correct, it is unlikely that you will be able to buy the part at retail plus all of the necessary tools for much less than $500, so having a professional do the job for $100 more is a bargain. If you were at home, and already owned the tools, then you could DIY for a fraction of the shop price–especially if you were willing to buy the parts online and wait for shipping.
Been 24hrs. Where’s papa?
How did you do ? Did you make it? Did Dad fix it ?
I had the same thing happen to me years ago. I made it to the neighboring town and back.
I doubt I would have made it much further. I probably drove for about 45 minutes.
My signal lights quit working and I even got pulled over. The cop had a huge attitude about using signals in his town. He chilled when I told him I thought my alternator went.


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Craftsy Block of the Month 2013 with Laura Nownes »
Type of item: Functional
Style: Traditional, Classic, Whimsical
100% cotton fabric and thread
What was your inspiration?
Still working from the black and white theme, but now adding color. I like vibrant colors.
What are you most proud of?
I don't know about "proud," but I'm as excited as a kid on Christmas morning! It thrills me to see an actual quilt emerging from my sewing machine!
What advice would you give someone starting this project?
Follow instructions carefully. Enjoy.


A data storage area room is actually a space in which businesses store digital information that they can use to run their particular business. You need to store this information properly therefore it can be contacted when needed. It will help keep your firm running proficiently and ensure that everyone in the company features access to the information they need.
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The sort of data storage space you choose must be based on how the data is used and how very much space it will require up. It’s important to know the potential requirements of the documents, when they must be salvaged, and whether you need to abide by regulatory suggestions.
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Cloud Data Storage is a great option for businesses that are looking to save money and get access to all their data every time they need it. This type of storage is convenient, simple to operate, and provides reputable data safety.
Data tiering is a method of automating data placement about different types of media channels, based on capability, performance and compliance. This can help businesses save money and time by ensuring that they’re not storage data inside the wrong tier or on unneeded media.
Scientists are working to develop new data storage area materials which you can use to store large amounts of information. This allows companies site link to store more data, which can help these people grow their organization.


JCM wrote:A video for this song would be awesome. I do not care who animates it.
Oh, so a video made by a 6-year-old on Mario Paint would be fine with you?
Alinite27 wrote:I figure it will be the animated video that is played in the background while they perform the song live.
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