text:
The Centre for Independent Journalism is working with malaysiakini.com and TroubadoursKL this year to celebrate World Press Freedom Day. So, what's that thinga..ma...jig?
Well, it all started in 1993 when Unesco got the United Nations General Assembly to proclaim May 3 as WPFD. Since then, countries, journalists and other interest groups have been organising celebrations to mark the day. This, year the world will remember assassinated journalists.
Last year, when the Centre for Independent Journalism thought about organising an event to mark WPFD, we realised that there were so few opportunities for independent bands to perform in KL. No thanks to certain quarters that think our indy bands are the source of the moral decadence in Malaysia, bands have a difficult time finding places to perform.
So, we decided to get them to perform for WPFD under the banner of `FREE VOICES', and what better place than Central Market. We're not bragging but I think 21 indy bands performing over the weekend in June last year was fantastic. Thanks to those who blogged about the performances – Lainie, wastedtalent, Joe Kidd.
Broken Scar at Free Voices concert in 2006
Crowd at Central Market
We are expanding the celebrations a little. We are calling it the People's Arts Fest to feature all types of spoken and written words, illustrations and expressions to symbolise freedom of expression.
And we are back in Central Market and are lucky to be able to use their new and flashy stage at the main entrance.
So, come with your friends and family, take part in the workshops or enjoy the performances. While you're there, learn a thing or two about DIY activism, what's cool and what's not about freedom of expression and media freedom in Malaysia.


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I thought it was time to take a few photos so you could see what I'm up to. Having made the signatures (sets of paper) and organised them into books, I marked them along the spine for the stitching. To do this I put the pages between 2 pieces of board and measured the spaces between the stitches, then used a fine hacksaw to make small cuts across the top of the spine. I had to make sure everything was perfectly level otherwise I could end up with different sized holes. Please note the excellent book press/vice Bob masterminded from a pine shelf, 2 brackets and 4 bolts and wingnuts.
Having prepared all the books it was time to start stitching using the cousoir I bought from Michel. A continuous length of tape was spread up and down between the top bar and the slot at the bottom, held in place with pins at the top and large needles at the bottom underneath the base. The tapes were then carefully positioned to line up with the marks on the paper. Then with a long linen thread and a needle I started sewing doing one signature at a time and knotting each subsequent one to the previous till the book was complete. The next step was to carefully pull the tape out till just enough was left to hold it all together, see the stack on the right, and trim the ends.
With all the books stitched I started on the glueing. This helps to avoid ugly gaps between the pages when you use the book. I glued the spines and pressed the glue into the paper using the bookbinder's bone, then when they were dry I shaped a round spine by tapping with a hammer and pressing along the spine at the edge of the fold with the bone. That's it for now, I'll be getting on with the next phase over the weekend.
Here are a couple more autumn pics from the nature journal.
These pink flowers are called Femmes Nus (naked ladies) here as they bloom before the leaves grow.

domain: library


text:
Let me tell you about a woman who goes by the name of “Scooter.” She attends a local prayer meeting that I frequent. Scooter became estranged from her family decades ago and spent seven long years homeless and living on the streets.
By God’s grace, Scooter was able to get off the streets and start attending church around 2005. With the help of some friends, she found an apartment. Walking is hard for her, so friends from church helped her purchase a scooter to help her get around. Thus, her name!
In the eyes of the world, Scooter may not be impressive, but in the eyes of God, she is beautiful. She is beloved. And she is precious! I think that Scooter has one of the purest hearts of anyone I know. “God has been good to me!” she often says. She loves the Lord and she treasures God’s people. She is faithful in prayer, generous, and grateful to everyone who has helped her. She is a fantastic witness to the love of Christ.
“One of These Least of Mine.” This month, we want to understand how we can take on the heart of God when we meet someone in Scooter’s situation. Or to put it in another way, we want to understand the rich tradition of our Catholic social teaching.
I am delighted to have Deacon Greg Kandra as our guest author on this subject. Deacon Greg gives us an overview of Catholic social teaching and shows us the special love God has for everyone who suffers from any kind of injustice or violence. He also gives us suggestions for how we might embrace this teaching more fully. And finally, he introduces us to Fr. Josh Johnson, a priest in Louisiana whose former parish has become a model for living out Jesus’ call to reach out to “these least brothers” of his (Matthew 25:40).
As I read Deacon Greg’s articles and learned about Fr. Josh’s parish, I was reminded of the early Church. After being filled with the Holy Spirit, these first Christians began to share their lives with each other and to care for the poorest among them. They even shared their money and material goods! Some of those who were wealthier sold “their property and possessions” and divided them “among all according to each one’s need” (Acts 2:45). I like to think that they cared for all of the “Scooters” in their midst. May we all become just as generous, selfless, and caring!
“Lord, help us see with your eyes and experience your love for every person, rich or poor. Lead us to love the least among us just as much as you love them. May we all hear these words from your lips: ‘Whatever you did for one of these least brothers of mine, you did for me’ (Matthew 25:40).”
Jeff Smith, President

domain: sociology


text:
Complete Engineering Laboratory Set-Up
Laboratory Supplier needed that can provide the entire set of laboratory equipment for setting up a new engineering laboratory.
Members of our Laboratory Outsourcing Network can use our online platform to communicate with the Lab Requestor, submit responses with quotes and have access to more information such as budget, location required, etc.
Need Laboratory Set-Up Testing or Scientific Research?
Save time and money searching. Simply, submit a Laboratory Set-Up request to find the laboratories or lab suppliers that best meet your needs.
INDIVIDUAL Materials Laboratory needed for glue testing on bamboo floor failure. view
Analytical Chemistry Laboratory needed for HPLC purity testing of of Clenbuterol HCl powder (CAS#21898-19-1) view

domain: chemistry


text:
From Paste magazine:
Artist and graphic designer Hyo Taek Kim has distilled the essence of his favorite films into beautiful, minimal works of art in “The Colors Of,” series. Each print features the main color palette used in the films of Hayao Miyazaki, expressed via long, horizontal strips of color.
Miyazaki is a legend in the animated film realm; he received an honorary Oscar at last year’s Governors Awards for his work on films like Princess Mononoke, Spirited Away and My Neighbor Totoro. Following Miyazaki’s recent announcement regarding plans for retirement, his production studio, Studio Ghibli, has said their latest release, The Wind Rises, will be their last.
Taek Kim strips down Miyazaki’s movies to their basic color schemes, conveying mood and tone in single uncomplicated swatches. One of the prominent themes throughout Miyazaki’s films is the exploration of simple life versus technological advances, so the minimalist prints are a straightforward but poignant way to remember the films. Check out our favorites in the gallery above. The color schemes are available as framed art, canvas prints and even rugs at Society6.

domain: artistic


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One shots with Axl, Slash and their daughter, Jessica throughout the years.
Slash leaned against the door frame, watching as Axl sat on the couch with Jessica sitting on his lap. He was mouthing words to her, trying to coax her into saying her first word but she was just giggling, toying with the cross necklace around his neck.
Axl sighed and kissed the top of her head, bouncing her slightly, smiling widely at how much she enjoyed it. Her small arms flew around, as if she was pretending to fly, and Slash chuckled, sipping on his tea.
“Come on, baby, say it. Daddy! Do it for me. Daddy!”
Slash shook his head, trailing over to the redhead, sitting down next to him. He set his tea on the coffee table in front of them, taking the baby out of his husband's arms. Slash pecked her on her forehead, causing her nose to scrunch up cutely, her small curls falling in front of her eyes. Her small fingers tugged at his own curls, laughing when he stuck out his tongue at her.
“No, honey. Ignore him. Dada...dada!”
Jessica just stared at the guitarist, and for a few seconds it looked like she was about to say something before her arms reached out for Axl again, clapping them, eyes set on his shiny cross necklace. Slash passed her over to Axl, who went back to mouthing the word again, but she was too interested on the necklace. He sighed again and slumped back into the chair, bouncing her when she pointed up, and again her arms waved about. The guitarist jumped when the front door bell echoed throughout the house. Slash looked over at Axl, who didn't even notice it, too focused on the way she was laughing, a grin on his face.
The brunette wished that he had the camera in that second, because that moment was just beautiful to him. He stood up and walked to the front door, unlocking it before opening it, revealing Izzy. The guitarist had a large box in his hands, and without an invitation, made his way into the house. Slash looked at him weirdly, wondering how he wasn't breaking a sweat, the box seemed quite heavy.
“Hey Slash! Where's the little one?”
Slash, eyeing the box suspiciously, pointed to the living room and the guitarist nodded before trailing over to the room. His smile widened when he saw the baby in Axl's arms, her green eyes lightening up when she saw the brunette. He ruffled her hair gently and sat the box down on the coffee table, tearing it open open when she pointed at it.
“I got a present for our youngest Gunner.”
He reached in and pulled out a small wooden rocking horse, that had her name carved in the middle, with butterflies and teddy's surrounding it. On the other side it also had 'Baby Gunner' carved in it, with roses around it. The couple gasped in astonishment and shock, trying to figure out how Izzy had thought of it.
Izzy took Jessica out of Axl's arms and carefully placed her on the horse, settling her hands on the handles and held onto her tight as he rocked her back and forth. She laughed loudly as well as Izzy, who was amused by the look on her face. He was normally quiet, but somehow, she always got him chuckling. He sat down next to her while Slash secretly took out the camera that was sitting on the table next to the front door and snapped a picture of them both.
Axl was still in shock,”How much did that cost, Iz?”
The brunette turned to him and shook his head,”It doesn't matter. I felt bad, you know, I wasn't here on her birthday last month, Axe. Her first one, that was crappy of me. See the look on her face? Call it a second birthday gift!”
Axl and Slash looked at eachother before the two grinned. Izzy continued to rock her back and forth, his dark eyes sparkling with happiness whenever she pulled at his bracelets and he settled her hands back on the handles. She eventually managed to rock herself but he still stayed close just in case she fell off. The three men watched her as Slash took pictures, the redhead still wondering how Izzy managed to keep this quiet, he could never keep a secret from him.
“That thing is amazing, dude!”
The three turned around to see Duff standing behind the couch, a playful look on his face. It was as if he wanted a go on it himself as he went around the couch and kneeled in front of the horse, while Izzy joined the other two on the couch.
“Hey, Jess! Having fun, huh?”
She smiled at him, pushing herself back and forth as the four looked on, each of them urging her to say their names. She ignored them and continued to play while they chatted, apart from Duff, who was back down next to her after being kicked off the couch by Izzy.
“Say it for uncle Duff, Jess.”
“No! Say Izzy, that's easier to say!”
Slash held up his hands when the two began to began to glare at eachother, ready to fight and he got in between them. Axl sat and watched, amused and slightly pissed that Slash had broke it up. He always wondered who would win in a fight between the two, just like he always wondered who bought more hair product. No one noticed that Jessica had managed to get off the horse and was now interested in the box it came in, she reached up and pulled it off the table, causing it to tumble down on top of her. She laughed happily, clapping her hands again.
”Your arguing over a child saying your name, you get that right? Remember when you fought over girls?”
The two nodded and chuckled at how stupid it was before the four to back to their conversation about the gig that was coming up. They always took Jessica with them, and while they were on stage, Beta, Axl's personal assistant, took care of the baby. She was more than that, she was apart of the family, and the baby adored her. Even Beta was trying to teach her some words of her own.
But always worrying about her, Axl would run off stage during Slash's solo's and make sure that she was OK. Their crowds always shouted her name at the end, and on rare occasions, he took the baby out.
They were shocked at how much she enjoyed it, expecting her to cry and scream at the noise but, just like the redhead, she loved being the centre of attention. Axl barely got mad on stage anymore, he was more calm and collected if anything happened during a concert. It was as if she had sorted everything. Ten minutes went by and Axl sensed that something was off, it was too quiet for his liking. His eyes drifted over to the horse and noticed that she wasn't on it.
Four pairs of eyes widened when they heard a loud giggle from across the room. Jessica was inside the box, amusing herself with the TV remote when there was a knock at the front door. Instead of waiting for an answer, it opened and Steven walked in, waving to the other Gunners before looking around for Jessica who had now managed to turn the box onto it's side. She rolled out of it, before crawling over to Steven, tugging at his trouser leg for some attention.
Duff high fived him,"Hey, Popcorn!"
“There she is!”
He lifted Jessica into the air, while she snuggled into him, tired of playing. His childlike personality was what Jessica loved about him, she had him around her little finger, he was always lifting her in the air and running through the house with her. Axl hated it, scared that he would drop her, but the look on her face always made him crumble. Her fingers played with his fluffy hair and she lifted her head, eyes fluttering sleepily, returning his smile before mumbling.
All was quiet, eyes moving over to Axl,"You fuc-"
He cut himself off because Jessica was in the room then suddenly, Axl shot up and went for Steven, causing Slash to pull him back. Jessica had finally falling asleep, cuddled into Steven's chest who was looking at the singer with a confused look on his face, but his face was beaming with pride at his nickname being first word. Slash lightly smacked Axl on forearm, warning flashing in his eyes.
“Wake her up and you're sleeping on the couch tonight.”

domain: literature


text:
Partners Group continues American energy push
Swiss alternative asset manager Partners Group has opened an office in Houston, Texas, its third US office as it gears up to make more investments in the country and Latin America.
In a statement, Partners said the Houston office would become its 18th global office. The firm said Todd Bright, managing director and head of infrastructure in the Americas, will head the Houston office, adding that Bright had a remit to build its investment activities in Latin America as well as the US.
Bright said the new office would serve as a “gateway” to opportunities in the energy sector: “Houston is the undisputed energy centre of the US and therefore this office opening is a natural next step for Partners Group as the firm deepens its coverage of the energy sector in the Americas."
He added: “Houston is also a major gateway to Mexico and other Latin American countries – so this office is the ideal complement to our existing São Paulo office in terms of expanding our access to both private markets investments and also our clients in Latin American markets."
Christoph Rubeli, co-chief executive of Partners Group, added: “In line with the opening of our Mumbai office earlier this year, the Houston office is another example of Partners Group putting into action our belief that a local presence is essential for sourcing attractive investment opportunities in key markets. In opening this office, we are underlining our interest in the US energy sector and showing that we remain positive on Latin America, despite recent negative investor sentiment surrounding emerging markets.”
Partners has already invested in the Latin American energy sector. In February, the firm bought Mexican gas company Fermaca in a deal worth roughly $750 million., while it is also aiming to raise about half a billion dollars to build a portfolio of natural gas pipelines in Mexico.

domain: news


text:
Play Free Online Zeus Tragamonedas Jugar Gratis Games
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domain: entertainment


text:
Boise punk label Hidden Home Records has made everything on their Bandcamp “pay-what-you-want” for the rest of the month. All donated proceeds will serve as a birthday gift to their mail guy, Mike.
HHR’s catalog features music by Filthy Hearts, Forever Unclean, Wicked Bears, and more. The label’s owner wrote in an Instagram post:
“[Mike] has happily chosen to do all of our mail order from Idaho since I moved across the country for my career. He is a one-in-a-million friend and deserves the world. Happy birthday Mike, I couldn’t do it without you. For the rest of September, everything on our Bandcamp is pay-what-you-want in celebration of MIIIIKE. All donations will go to him, cuz we rarely break even as it is. Link in bio.”
You can visit the Hidden Home Records Bandcamp here, or check out their new compilation below if you’re unfamiliar with the label.


text:
ILVA steel mill chief says Italy court ruling threatens jobs
MILAN (Reuters) - The jobs of thousands of workers at ILVA, Europe's biggest steel plant, are at risk if the factory in southern Italy has to stop production as ordered on Friday by an Italian judge, ILVA Chairman Bruno Ferrante said in a newspaper interview on Sunday.
"I don't even want to pronounce that word (layoffs) ... But if they block production here, the outlook gets more complicated not just for the almost 12,000 employees, but also for the whole supply chain," Ferrante said in an interview with Italian newspaper la Stampa.
On Saturday, Ferrante said he would appeal a ruling by preliminary court judge Patrizia Todisco saying the factory must not produce steel while it makes court-ordered improvements to its production line.
At the request of prosecutors in Taranto, Todisco had originally ordered the factory's partial closure last month because of concerns that pollution was harming the health of the workers and local residents.
But an appeals court ruled last week that ILVA could remain open as it upgraded its production line to meet regulatory standards, a decision the company interpreted as a green light for continued steel production.
The appeals court also named Ferrante a court administrator of the factory.
But in what looks increasingly like a rift within the Taranto courthouse, Todisco on Saturday said Ferrante was not among the pool of administrators and reappointed Mario Tagarelli, who had been excluded by the appeals court, a judicial source said.
"The closure and turning off of the plant must be avoided at all costs, something that would cause irreparable damage. Nothing will be left untried," newswire ANSA reported Italy's Industry Minister Corrado Passera as saying on Sunday.
Passera said Environment Minister Corrado Clini and Justice Minister Paola Severino were also dealing with the matter, keeping Italian Prime Minister Mario Monti constantly briefed. Continued...

domain: law


text:
Answerable Sentence Examples
The president of the republic is not answerable at law for his official acts.
Europeans are answerable to the Italian civil code.
The Government Chief Whip is directly answerable to the Prime Minister.
Different scales of operation are covered, from the Treasurer doing it all, to significant paid finance staff answerable to the Board.
Most students will be over the age of 18 and are not legally answerable to their parents.Advertisement
One characteristic point which appears very early is that they felt themselves called upon to vindicate the laws of divine righteousness in national matters, and especially in the conduct of the kings, who were not answerable to human authority.
The land-tax was doubled and trebled by war, by the pensions of the nobles, by an extortion the profits of which Richelieu disdained neither for himself nor for his family; and just when the richer and more powerful classes had been freed from taxes, causing the wholesale oppression of the poorer, these few remaining were jointly and severally answerable.
By making the police properly answerable to the communities they are meant to be serving Ã¢¦ .
We don't ban organizations, but we do make our elected representatives answerable for their actions.
They would remain answerable to a supervisor or manager who would take overall responsibility for an area or policy or even the whole business.Advertisement
The EU should be held answerable to the Court of Auditors, and not the other way around.
In February 1999, the Cabinet Office announced that 111 executive NDPBs and 47 advisory bodies would be made answerable to the PCA.
It is not answerable in its views to any masters.
April-November 1933 - The Gestapo were only answerable to Goring.
They are therefore answerable for all payments, including those made by Direct Debit.Advertisement
We already have regional government by quango and civil servant - the point is to make regional viceroys answerable to local voters.
Read through each section and highlight areas that are not readily answerable.
During the earlier days of the republic the doge had been a prince elected by the people, and answerable only to the popular assemblies.
The subjugation of the Saxons, who were divided into four main branches, was rendered more difficult by the absence of any common ruler, and of a central power answerable for the allegiance of the separate tribes.
The ministers were no longer to be the members of a great party, acting together in pursuance of a common policy accepted by them all as a united body; they were to become nominees of the court, each holding himself answerable not to his colleagues but to the king, separately, individually and by department.Advertisement
We are ultimately answerable to God who owns everything.
Now, if his use of the term was stricter than the customary use, he can hardly be held answerable for the latter.


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Leicester Royal Infirmary - Balmoral Building
Leicester LE1 5WW
An exhibition of 20 portraits of NHS Heroes by Lisa Timmerman is now installed at Leicester Royal Infirmary. It features 20 portraits of NHS staff from across the country, including many faces from the teams at University Hospitals Leicester
Lisa Timmerman, who paints from her home in Foxton, Market Harborough, was inspired by artist Tom Croft who started the initiative with the #portraitsfornhsheroes on Instagram. Lisa painted the portraits of their local NHS staff as gifts, as a way of thanking them for their hard work and efforts during the pandemic. She picked the number 20 to reflect the year of the pandemic. Lisa organised 3 sponsors to cover all the costs of the exhibition, including Giclee printing & framing costs, and postage to send the original paintings out to the NHS heroes as keepsakes.
The portraits can be seen on the first floor of the Balmoral building at Leicester Royal Infirmary in the main walkway by the WRVS cafe. As the exhibition was going up, staff were stopping to say how happy they were to have it there and how art really does help.
“It has been uplifting to be able to do something for them to show our gratitude and an experience I will never forget,” says Lisa.
Full details about each painting and information about the individual NHS heroes are on Lisa Timmerman’s website:


Paste a url where
can be downloaded
100% Stock replica of the first ever Moon lander designed to be used in Real Solar System. Watch my latest video for the demonstration of this behemoth rocket :D
- Type: VAB
- Class: lander
- Part Count: 511
- Pure Stock
Do you really want to downvote this?
Don't forget, people build craft at all skill levels, just 'cos something is 'newbish' doesn't mean it needs hatin'.
It will cost you 5 of your own points to downvote


text:
Stay Tuned! Full Conference Program to be released in early 2024!
Chris Beaudry – “The Heroes and Dragons of Mental Health”
The concept of Functional Mental Health is an individual process that reflects each person’s life, their own experiences, the context of these experiences, and the related social determinants of health. Discovering and rediscovering what works for you today, not tomorrow or yesterday, but today is functional mental health. It takes a lot of courage and vulnerability to discover what path is the right one for you today.
Chris speaks to and supports his audience to reflect on their own experiences and the aspects of functional mental health that can be most useful to them through the sharing of his own journey and process with trauma, addictions, and mental illness.
Dr. Jan DeFehr – “Mending Psychiatric Divisions, Crafting a Liberating Ethic of Care”
Mental health promotion campaigns and curricula encourage early detection, diagnosis, and treatment of what psychiatry classifies as mental disorder. This familiar pathologizing approach separates those deemed disordered from others presumed to be normal. Problematically, mental health promotion omits critical knowledge in the field of mental health. Critical knowledge exposes routine harm and significant misinformation in mainstream mental health. Produced over decades by patients and ex-patients, academics, and professionals, the critique of mental health has intensified in recent years. Omission of this critique impedes individual capacity to make informed decisions about professional intervention.
Dr. DeFehr will outline core areas of mental health critique within current peer-reviewed scholarship in critical psychology, critical psychiatry, and mad studies. Drawing on professional ethics standards, she will argue that members of the public are entitled to full disclosure of relevant critical knowledge, and professionals carry the responsibility to disclose. Dr. DeFehr will describe a Winnipeg community health clinic’s emerging initiative to build client access to critical mental health knowledge. Already equipped with conventional mental health resources, the clinic’s mental health informed choice action research project is generating new online and printed critical mental health resources; the formation of a Critical Mental Health Working Group representing major areas within the clinic; and new, board-supported, informed choice policies and practices. The clinic’s collective action is de-automating the dividing practices implicit in psychiatric diagnosis. It is enabling a wider range of options and cultivating an unprecedented standard of care rooted in solidarity and informed choice.
Sera Davidow – “Mental Health through a Harm Reduction Lens”
The default approach to emotional distress within Westernized societies is to medicalize and locate the problem within the individual. However, our medical systems – while adept at addressing many actual medical issues (for example, a drug overdose, whether intentional or otherwise) – has notoriously low rates of success at resolving concerns related to what they typically call “mental illness.” In fact, the World Health Organization (WHO) has stated that being a part of a Westernized society is a predictor that one will never fully recover. Davidow’s presentation will delve into the whys and impacts of this failure, while exploring a fundamentally different path called ‘harm reduction’ as it relates to common experiences within the psychiatric system such as hearing voices, self-injury and suicidal thoughts. Personal story and real life examples will be intertwined with research and strategies to help illustrate ideas presented. Themes explored will include the power of loss of power, the essential nature of supporting someone to make meaning of their own experiences, redefining ‘the problem,’ and harm reduction as a pathway to equity and cultural representation.
This program is subject to change.

domain: medical


text:
Metallothionein (MT) is a low-molecular-weight, cysteine-rich protein that contains heavy metals such as cadmium and zinc. The biological function of MT in platelets is not yet understood. Therefore, the aim of this study was to systematically examine the inhibitory mechanisms of metallothionein in platelet aggregation. In this study, metallothionein concentration-dependently (1-8 μM) inhibited platelet aggregation in human platelets stimulated by agonists. Metallothionein (4 and 8 μM) inhibited phosphoinositide breakdown in [ 3H]-inositol-labeled platelets, intracellular Ca+2 mobilization in Fura-2 AM-loaded platelets, and thromboxane A2 formation stimulated by collagen. In addition, metallothionein (4 and 8 μM) significantly increased the formation of cyclic GMP but not cyclic AMP in human platelets. Rapid phosphorylation of a protein of Mr 47,000 (P47), a marker of protein kinase C activation, was triggered by PDBu (100 nM). This phosphorylation was markedly inhibited by metallothionein (4 and 8 μM) in phosphorus-32-labeled platelets. In an in vivo thrombotic study, platelet thrombus formation was induced by irradiation of mesenteric venules in mice pretreated with fluorescein sodium. Metallothionein (6 μg/g) significantly prolonged the latency period for inducing platelet plug formation in mesenteric venules. These results indicate that the antiplatelet activity of metallothionein may involve the following pathways: (1) metallothionein may inhibit the activation of phospholipase C, followed by inhibition of phosphoinositide breakdown and thromboxane A2 formation, thereby leading to inhibition of intracellular Ca+2 mobilization; (ii) Metallothionein also activated the formation of cyclic GMP in human platelets, resulting in inhibition of platelet aggregation. The results strongly indicate that metallothionein provides protection against thromboembolism.
|頁（從 - 到）||1321-1328|
|期刊||Experimental Biology and Medicine|
|出版狀態||已發佈 - 12月 2003|
ASJC Scopus subject areas
- 生物化學、遺傳與分子生物學 (全部)


GAPMAN road roughness and profile measuring profilometer measures and displays the various profile parameters, including the average angle of inclination, the rut depth of a road and International Roughness Index (IRI) and more. In IRI measurement mode the profilometers display the average IRI value of the last covered surface meter.
The portable walking profiler GAPMAN includes a control and a sensor module that are connected by an adjustable length handle. The device is on wheels and can easily be rolled across the measured surface by a single operator.
The control module includes a number of setup and control options, and displays the recent measurement results. Different measuring modes can be selected to determine how to calculate the value and position of the maximum deviation for the profile.
GAPMAN comes with an integrated GPS module that stores the coordinates of each measurement location. All measured data is stored and can be downloaded to a computer via USB or Bluetooth connection.
Features and Benefits
Wheeled across a measured surface by a single operator
Selectable setup and control options
IRI measurement mode
Real-time calculation and display of surface profile parameters
Integrated GPS unit determines and stores measurement locations
USB or Bluetooth computer connection
Data storage capacity
Profile measuring step
Profile height measuring resolution
Slope measurement resolution
2x AA alkaline batteries
Operating time on battery power
18, with GPS powered on
-10 to 50
70 x 40 x 20


text:
HOOKÉSee blog post
People We Met : Dan Despres – Marlon PrinceSee blog post
Atlantic Salmon season kickoff in GaspéSee blog post
Gaspé fly x hooké fly boxesSee blog post
The Fly FISHER BOOK – Now availableSee blog post
We love to hear from you, don’t hesitate to write to us for any questions, comments or suggestions.

domain: hobby


text:
Brathian is an action platformer with some touches of exploration and a cute retro inspired look.
Discover this land that used to be magical, but had all its magic sealed into a crystal due to many wars fought for its power.
Play as Edgar or Amy in an adventure to defeat and use the power of the guardians to stop whoever is trying to snatch the crystal.
Single and two player co-op modes
Power-ups to open secrets, increase your health, damage and mobility
Cute characters and enemies
Gameplay that can be finished in one go
Windows 7 (64-bit) or newer
2ghz 64-bit processor and operating system
2 GB RAM
OpenGL 2.1 or better
20 MB available space

domain: game


text:
Don’t have time to browse at the Library? Looking for a new author to read? Need help finding the perfect book? We’ve got you covered with Browsing Bundles for teens and adults!
Browsing Bundles are pre-selected books, audiobooks, DVDs, graphic novels, music, games, or other items (4-6 items per bundle) based on your likes.
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I’ve been meaning to feature Cal Ruddy on unZined for a while now. Noticed Cal first, when I went along to one of his previous single launches. Long story short, I was impressed by his unique, retro sounding style that seemed to go against the current music scene – a lone musician going against the tide. The style of choice that Cal brings to his music is a shout out to rock n roll when it was at its purest in and around the late 50’s, more particularly the Skiffle style. He does it well and it suits his singing style. Been following his tenacious progress on the music scene since and more recently he got in touch for me to review his latest single, a song which is commonplace in his set list, Maria.
From the off, the listener is transported to another time, one where synth sounds and EDM were not even thought of. After a quirky intro, Cal croons through soft vocals, akin to the like a mix of Roy Orbison , Buddy Holly and a bit of Bob Dylan, as the steady bass and drums carry us on through the song. Spaced through the song are little breaks with hand clapping, a clever inclusion as, Cal Ruddy his been known to use it to encourage the audience to participate with their own at his live gigs. (I myself have been swayed by his cheeky smile more than once into being an unofficial backing-clapper)
The chorus will no doubt have even the stubborn music critics singing along. The catchy lyrics will be stuck in your head for a while after listening to the chorus. The expertly played accompanying bass, drums and clean retro sounding guitar only adds to the rock and roll feeling Cal wants to and succeeds at putting across. Overall, a professional sounding, up tempo, rock and roll track, one which suits Cal Ruddy’s vocal style and one which will be unlike many songs heard today.
Click the links below for more info on Cal Ruddy:


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Last time Basic Passive Rate reached this level was in August, 14th, 2008.
Last week the Central Bank, Treasury Ministry, state-owned and private banks reduced their interest rates, reported the Central Bank. "Nevertheless, state owned banks had the strongest influence in this reduction, as they lowered their interest rates the most".
Starting Thursday, September 30, the Passive Basic Rate (TBP) will stand at 7.50%.
El Financiero, on its website explains "the TBP is a weighted average interest rate of gross uptake in Colones, negotiated by financial brokers operting in the country as well as by Central Bank and the Ministry of Finance.”


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The local barber shop is a local landmark, with an historic barbershop, salon, and restaurant. The barber shop has been around for over 200 years and is nestled in the heart of the city. The barber shop’s walls are painted in the colors of the city’s skyline and is located in the city’s oldest neighborhood.
The barber shop is a local landmark, and while most of the other buildings in the city are still in decent shape, this barber shop has been in the same location for over 200 years. The barber shop’s walls are painted in the colors of the citys skyline and is located in the citys oldest neighborhood.
The barber shop is a local landmark, and while most of the other buildings in the city are still in decent shape, this barber shop has been in the same location for over 200 years. The barber shops walls are painted in the colors of the citys skyline and is located in the citys oldest neighborhood.
We’ll start with the best barber shop I’ve ever come across. They were built in the 1980s. The barbers themselves are made in the 1960s and 70s. The main bar is actually a little more modest than the rest of the shop, but they still have a good look.
They have a new barber shop now, but there’s still some time left for the previous barber shop to be renovated. There’s been much discussion about whether the barber shop is worth renovating, but there’s no question that it has enough character and integrity to be worth the effort.
The barber shop is not really a barber shop at all. It’s more of a “wedding” shop for the barbers themselves, where they will do their business and then leave the barber shop in the background, allowing the barber to take care of business in the shop itself. The shop itself is a small, intimate barbershop. The other barbers working there are all elderly.
There are just two barbers in the shop. Theres one barber who does business in the barber shop, the other one that does business outside, and the shop owner who is pretty much the lone wolf in the barber shop. The shop is pretty clean and well kept. The barber shop is just a pretty spot.
With this, you can expect to get into a lot of arguments with your patrons. If you’re going to go to a barber shop, you’ve probably got a couple of good, cool people there. In fact, there are many bars to go to. There are a couple of barbers who really need to put on their own skin.
I don’t know what you mean by the lack of dialogue inside the shop for the people there in the barber shop. Youve probably had some pretty good conversation with many of them right before you go to the barber shop.
The word “shame” in this paragraph is just so that I can’t help asking some questions about the place I’m in. I mean, there was a time when I was in my early 50s. I’ve always had a bad feeling about it. It’s one of the perks of being a good barber, and that feeling is that you see things that you don’t feel.

domain: geography


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Download the Free Unbound MEDLINE PubMed App to your smartphone or tablet.
Available for iPhone, iPad, iPod touch, and Android.
Gastroenterology AND Cancer, small intestine [keywords]
- Role of p53 in Anticancer Drug Treatment- and Radiation-Induced Injury in Normal Small Intestine. [Journal Article]
- Cancer Biol Med 2012 Mar; 9(1):1-8.
In the human gastrointestinal tract, the functional mucosa of the small intestine has the highest capacity for absorption of nutrients and rapid proliferation rates, making it vulnerable to chemoradiotherapy. Recent understanding of the protective role of p53-mediated cell cycle arrest in the small intestinal mucosa has led researchers to explore new avenues to mitigate mucosal injury during cancer treatment. A traditional p53 inhibitor and two other molecules that exhibit strong protective effects on normal small intestinal epithelium during anticancer drug treatment and radiation therapy are introduced in this work. The objective of this review was to update current knowledge regarding potential mechanisms and targets that inhibit the side effects induced by chemoradiotherapy.
- Relationships of CDXs and apical sodium-dependent bile acid transporter in Barrett's esophagus. [Journal Article]
- World J Gastroenterol 2013 May 14; 19(18):2736-9.
Barrett's esophagus (BE) is characterized by intestinal metaplasia with the differentiated epithelium replaced by another type of epithelium morphologically similar to normal intestinal epithelium. The metaplasia is preceded by bile and acid reflux into the esophagus. BE is a premalignant condition associated with increased risk of esophageal cancer, especially esophageal adenocarcinoma. The Caudal-related homeodomain transcription factors Caudal-related homeodomain transcription factor CDX1 and CDX2 are expressed exclusively in the small and large intestine, playing important roles in proliferation and differentiation of intestinal epithelial cells. Ectopic expression of CDX1 and CDX2 occurs in BE. The apical sodium-dependent bile acid transporter (ASBT) is expressed primarily in terminal ileum where it is a key factor for intestinal reabsorption of bile salts. In addition to upregulation of CDX1 and CDX2, ASBT expression is up-regulated in BE. Furthermore, both CDX1/CDX2 and ASBT expressions are down-regulated in high-grade esophageal dysplasia. The alteration of the above-mentioned factors calls for attention: what is the relationship between CDXs and ASBT aberrant expression in BE? In this commentary, we discuss this issue on basis of the recent study done by Ma et al.
- Intestinal Obstruction due to Complete Transmural Migration of a Retained Surgical Sponge into the Intestine. [Journal Article]
- Case Rep Gastroenterol 2012 Sep; 6(3):754-9.
A 56-year-old woman with a history of gynecological surgery for cervical cancer 18 years previously was referred to our hospital for colicky abdominal pain, nausea and vomiting. Intestinal obstruction was diagnosed by contrast-enhanced computed tomography (CT) which showed dilation of the small intestine and suggested obstruction in the terminal ileum. In addition, CT showed a thick-walled cavitary lesion communicating with the proximal jejunum. (18)F-fluorodeoxyglucose positron emission tomography showed abnormal uptake at the same location as the cavitary lesion revealed by CT. The patient underwent laparotomy for the ileus and resection of the cavitary lesion. At laparotomy, we found a retained surgical sponge in the ileum 60 cm from the ileocecal valve. The cavitary tumor had two fistulae communicating with the proximal jejunum. The tumor was resected en bloc together with the transverse colon, part of the jejunum and the duodenum. Microscopic examination revealed fibrous encapsulation and foreign body giant cell reaction. Since a retained surgical sponge without radiopaque markers is extremely difficult to diagnose, retained surgical sponge should be considered in the differential diagnosis of intestinal obstruction in patients who have undergone previous abdominal surgery.
- Involvement of liver-intestine cadherin in cancer progression. [Journal Article, Research Support, Non-U.S. Gov't]
- Med Mol Morphol 2013 Mar; 46(1):1-7.
Cadherins constitute a superfamily of Ca(2+)-dependent cell adhesion molecules that play critical roles in the maintenance of tissue structure and morphogenesis. Their dysregulation is commonly observed in a variety of cancers. Liver-intestine cadherin (LI-cadherin), which was so named in view of its sole expression in the liver and intestine of the rat, is a structurally unique member of the cadherin superfamily, possessing seven cadherin repeats within the extracellular cadherin domain and only 25 amino acids in the cytoplasmic domain. Its adhesive property does not require any interaction with cytoplasmic components such as catenins, and it responds to small changes in extracellular Ca(2+) below the physiological plasma concentration. In humans, the distribution of LI-cadherin is limited to the duodenum, jejunum, ileum, colon, and part of the pancreatic duct. Data accumulated from studies of the biological characteristics of LI-cadherin have shown that it plays an important role in the pathophysiology of human cancers. Here, we review recent information about LI-cadherin and its implications for cancer progression.
- [A case of small intestinal stage IV gastrointestinal stromal tumor in which long-term disease control was maintained for more than 10 Years through a multidisciplinary team approach]. [Case Reports, English Abstract, Journal Article]
- Gan To Kagaku Ryoho 2012 Nov; 39(12):1898-901.
The prognosis of metastatic or recurrent gastrointestinal stromal tumors (GISTs) accompanied by multiple hepatic metastases and peritoneal dissemination is very poor. We encountered a case of stage IV small intestinal GIST with multiple hepatic metastases and peritoneal dissemination that were observed after resection of the primary lesion. Multidisciplinary treatments were performed over time, including hepatic resection, radiotherapy, imatinib therapy, sunitinib therapy, and transcatheter arterial chemoembolization, and the disease had been brought under control following resection of a primary lesion 14 years ago. The patient was a 49-year-old woman diagnosed with hemorrhagic stool in July 1998, when a computed tomography scan revealed an 8-cm-diameter tumor in her small bowel. Partial resection of her small bowel was performed and the pathological diagnosis was a high-risk GIST showing 15 mitoses per 50 high power fields. Several metastases developed in the S4 and S5 segments of the patient's liver 3 years after resection of the primary lesion, and a central two-segmental resection of the liver was performed. Furthermore, 1 year after this procedure, peritoneal dissemination developed near the pancreas, for which radiotherapy was performed. Four months later, the patient again developed multiple liver metastases and was started on treatment with 400 mg imatinib per day, achieving a partial response(PR). Five years and 6 months after imatinib initiation, resistance emerged in one of the liver metastases. The patient was switched to sunitinib(50 mg per day), but was diagnosed with progressive disease at the end of the second course and the procedure was discontinued. Treatment with 400 mg of imatinib per day was resumed, and transcatheter arterial chemoembolization was performed twice over a 17-month period for the resistant hepatic region and a PR was achieved each time. We were able to maintain a PR in this patient; other metastases indicated the effectiveness of imatinib therapy. Therefore, a multidisciplinary team approach can be effective in achieving long-term disease control in patients with metastatic or recurrent GIST.
- Identification of lineage-uncommitted, long-lived, label-retaining cells in healthy human esophagus and stomach, and in metaplastic esophagus. [Comparative Study, Journal Article, Research Support, Non-U.S. Gov't]
- Gastroenterology 2013 Apr; 144(4):761-70.
The existence of slowly cycling, adult stem cells has been challenged by the identification of actively cycling cells. We investigated the existence of uncommitted, slowly cycling cells by tracking 5-iodo-2'-deoxyuridine (IdU) label-retaining cells (LRCs) in normal esophagus, Barrett's esophagus (BE), esophageal dysplasia, adenocarcinoma, and healthy stomach tissues from patients.Four patients (3 undergoing esophagectomy, 1 undergoing esophageal endoscopic mucosal resection for dysplasia and an esophagectomy for esophageal adenocarcinoma) received intravenous infusion of IdU (200 mg/m(2) body surface area; maximum dose, 400 mg) over a 30-minute period; the IdU had a circulation half-life of 8 hours. Tissues were collected at 7, 11, 29, and 67 days after infusion, from regions of healthy esophagus, BE, dysplasia, adenocarcinoma, and healthy stomach; they were analyzed by in situ hybridization, flow cytometry, and immunohistochemical analyses.No LRCs were found in dysplasias or adenocarcinomas, but there were significant numbers of LRCs in the base of glands from BE tissue, in the papillae of the basal layer of the esophageal squamous epithelium, and in the neck/isthmus region of healthy stomach. These cells cycled slowly because IdU was retained for at least 67 days and co-labeling with Ki-67 was infrequent. In glands from BE tissues, most cells did not express defensin-5, Muc-2, or chromogranin A, indicating that they were not lineage committed. Some cells labeled for endocrine markers and IdU at 67 days; these cells represented a small population (<0.1%) of epithelial cells at this time point. The epithelial turnover time of the healthy esophageal mucosa was approximately 11 days (twice that of the intestine).LRCs of human esophagus and stomach have many features of stem cells (long lived, slow cycling, uncommitted, and multipotent), and can be found in a recognized stem cell niche. Further analyses of these cells, in healthy and metaplastic epithelia, is required.
- Notch in the intestine: regulation of homeostasis and pathogenesis. [Journal Article]
- Annu Rev Physiol 2013.:263-88.
The small and large intestines are tubular organs composed of several tissue types. The columnar epithelium that lines the inner surface of the intestines distinguishes the digestive physiology of each region of the intestine and consists of several distinct cell types that are rapidly and continually renewed by intestinal stem cells that reside near the base of the crypts of Lieberkühn. Notch signaling controls the fate of intestinal stem cells by regulating the expression of Hes genes and by repressing Atoh1. Alternate models of Notch pathway control of cell fate determination are presented. Roles for Notch signaling in development of the intestine, including mesenchymal and neural cells, are discussed. The oncogenic activities of Notch in colorectal cancer, as well as the tumor suppressive activities of Atoh1, are reviewed. Therapeutic targeting of the Notch pathway in colorectal cancers is discussed, along with potential caveats.
- Double-balloon endoscopy in patients with Peutz-Jeghers syndrome. [Comparative Study, Journal Article]
- Turk J Gastroenterol 2012; 23(5):496-502.
Peutz-Jeghers syndrome is a rare hereditary syndrome characterized by mucocutaneous pigmentation and hamartomatous polyps of the gastrointestinal tract, especially in the small intestine. Double-balloon endoscopy is a new endoscopic technique that enables both endoscopic visualization of the entire small bowel and therapeutic interventions in a single procedure. In this study, we evaluate the efficacy and safety of double-balloon endoscopy for both treatment and surveillance of patients with Peutz-Jeghers syndrome.We retrospectively evaluated 7 consecutive patients who were referred to Dokuz Eylül University, Gastroenterology Department, with the diagnosis of Peutz-Jeghers syndrome between 2007 and 2010.Patients with Peutz-Jeghers syndrome (M/F: 5/2) underwent a total 31 double-balloon endoscopy procedures: 21 by the oral route, 9 by the anal route, and 1 intraoperatively. All of the patients had a history of laparotomy and small bowel resection due to complications such as invagination and ileus. In 7 patients, we found a total of 110 polyps ≥10 mm in diameter (10-100 mm) and polypectomies were performed in all of them. The only complication was a bleeding after polypectomy, which was controlled by sclerotherapy. In 1 patient, because of the intraabdominal adhesions due to past laparotomies, polypectomy was done by intraoperative endoscopy. In 2 of our patients, we made surveillance colonoscopies, found new polyps in the small intestine, and performed polypectomies.Double-balloon endoscopy is an effective and safe endoscopic technique, and represents a milestone for both treatment and surveillance of patients with Peutz-Jeghers syndrome. Polypectomies made in the small intestine might decrease the complication rate due to these polyps and the need for surgery.
- Efficacy of flexible spectral imaging color enhancement on the detection of small intestinal diseases by capsule endoscopy. [Clinical Trial, Journal Article, Validation Studies]
- J Dig Dis 2012 Dec; 13(12):614-20.
The aim of this study was to estimate the efficacy of flexible spectral imaging color enhancement (FICE) on the detection of small intestinal diseases by capsule endoscopy (CE).Six individuals without significant lesions and 18 patients with following diseases were selected: four tumors, five angioectasias, seven ulcerative diseases, one ulcerative lesion and tumor and one ulcerative lesion and angioectasia. Three endoscopists reviewed all CE videos on standard and three types of FICE modes and compared their sensitivity and specificity for detection of small intestinal diseases.The overall sensitivity of CE was 94.4% at standard mode, 90.7% at FICE channel (Ch) 1, 87.0% at FICE Ch 2 and 87.0% at FICE Ch 3 and the overall specificity of CE was 66.7%, 55.6%, 77.8% and 66.7%, respectively, per patient. There was no significant difference between the standard and each FICE mode. In per-lesion analysis, FICE Ch 1 detected more angioectasias and ulcerative lesions than the standard mode (angioectasia, 25.7 vs 21.0, P = 0.005; ulcerative lesions, 19.3 vs 14.0, P = 0.06). However, FICE Ch 1 missed more tumors than the standard mode (4.3 vs 10.0, P = 0.003).Although FICE Ch 1 is better in detecting angioectasias and ulcerative lesions and worse in tumors or polyps than the standard mode, the patient-based sensitivity and specificity of small intestinal diseases are not different between standard and each FICE mode. Further experiences with and improvement of FICE are required.
- Single-balloon enteroscopy for small bowel diseases: results from an initial experience at a single Chinese center. [Journal Article]
- J Dig Dis 2012 Dec; 13(12):609-13.
This study aimed to evaluate the performance, diagnostic yield, and safety of single-balloon enteroscopy (SBE) at a Chinese tertiary-care center.A total of 67 patients with suspected small bowel diseases who underwent SBE via the oral and/or anal routes from January 2009 to August 2011 were retrospectively analyzed. Data were extracted from electronic clinical and endoscopy records. The indications, SBE procedure time, diagnostic yield and complications were summarized and evaluated.A total of 42 SBE procedures through the oral route and 38 via the anal route were performed in these 67 patients. Patients were referred mainly for obscure gastrointestinal bleeding (OGIB) (40.3%) and abdominal pain (29.8%). The mean procedure duration was 68.1 min from the oral cavity and 77.5 min from the anus. The estimated depth of insertion was 247.6 ± 80.3 cm from the oral cavity and 131.1 ± 68.7 cm from the anus. The overall significant diagnostic yield was 68.7%. In patients with OGIB and unexplained chronic abdominal pain, the diagnostic yield was 74.1% and 50.0%, respectively. There were no significant complications.SBE appears to be a safe and effective method for the diagnosis and treatment of deep small bowel disease.


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Golf Koh Samui offers a peaceful and relaxing golf tour to Thailand. From ancient Buddha images to modern, colorful temples, there is a vast selection of interesting places to visit and sights to see. The white sandy beaches are fringed with coconut palms; with the top hotels located close by. It is the perfect setting for a custom golf tour Thailand and can be visited as part of a broader trip through Thailand golf tours.
The Island is now host to a championship standard course in Santiburi Samui Country Club, which has stunning views of the ocean and is getting a name as one of the top Thailand golf courses.
A custom golf tour Thailand, Koh Samui also offers a unique dining experience, its seafood dishes are unrivalled as well as a wide selection of international cuisines. The variety of seasonal tropical fruits are unsurpassed it is referred to as the island of coconut trees. Unique jewelry, souvenirs, textiles and handicrafts are produced by the local people and make night markets bustling vibrant centers. No golf tour Thailand is complete without a trip to this secluded paradise.

domain: travel


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A Taste of Luxury Stitched into Nature: Guayaquil’s Secret GardenNovember 11, 2021
Top 5 Guayaquil Restaurants for Relishing Ecuadorian Fusion FoodNovember 12, 2021
Guayaquil and the Galapagos, 2 destinations that you must visit…
Guayaquil is Ecuador’s main port, one of the most important on the South Pacific coast. It is a city model that progresses in freedom. It is the gateway to Galapagos, World Natural Heritage and world center for the evolution of species.
5 reasons for you to visit Guayaquil and from Guayaquil travel to Galapagos:
A city that will captivate you with its charms and will enhance your experience in the Enchanted Islands!
1. The weather is similar to the Galapagos Islands
The average temperature influenced by the cold Humboldt current is 24ºC to 26º C, which allows you to wear the same light clothes, typical of a warm and tropical weather.
2. Guayaquil is located just 4 meters above sea level
An advantage that guarantees your health and travel because there is no danger of suffering the effects of height caused by temperature changes.
3. Guayaquil is connected worldwide
In the José Joaquín de Olmedo International Airport- chosen by users as one of the best in the world in its category- operates 17 airlines with a large number of direct, non-stop and connecting flights that goes to Asia, Europe, North America, South America, Central America and the Caribbean; therefore, Guayaquil can be easily reached.
4. Most of the main 5 and 4 star hotels are 15 minutes from the airport
Your stay is guaranteed with excellent quality and service provided by the hotel chains located near the airport, with the advantage of being able to arrive and leave the city in the shortest possible time.
5. Guayaquil is the closest city to the Galapagos Islands
Due to its proximity of 1 hour and 45 minutes, almost all flights that operate from the José Joaquín de Olmedo International Airport are directly connected to the main Galapagos Islands: Santa Cruz and San Cristóbal, with 8 daily round-trip frequencies.
We invite you to visit Guayaquil, to enjoy it and explore it, to live the most beautiful experiences of culture, history, gastronomy, nature, adventure and fun.
Scan the QR code and plan your trip to live the most unforgettable experiences in the South Pacific Pearl. Start your tour in Guayaquil, fall in love with our destination and continue your trip to Galapagos.
Be amazed and live a unique and splendid world that the Enchanted Islands- Natural Heritage of Humanity- offer you.
Guayaquil awaits you with the warm hospitality of its people.
We are sure you will come back!
Do not forget that an experience is worth a thousand words. Discover both destinations and enjoy!


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The deeply flawed state school reorganization plan known as “One Newark” faces a federal investigation. In response to a detailed request for a probe from PULSE New Jersey, a parent activist group founded by Johnny Lattner and Sharon Smith, the U.S. Department of Education will determine whether the plan–which has confused the lives of thousands of city children and their parents–violates the civil rights of Newark parents.
Lattner and Smith, joined by national Journey for Justice director Jitu Brown, will announced the details of the investigation Wednesday at noon during a press conference scheduled for the steps of City Hall.
“We made the case that One Newark’ discriminates against children, parents, and teachers, especially in the South Ward,” said Smith, who has been working on bringing the feds into Newark for months.
Smith says she hopes the investigation, authorized by Title 6 of the federal Civil Rights statute, will be prelude to suspending the “One Newark” plan and replacing it with what Brown calls “sustainable school transformation.”
Brown’s organization is an umbrella group seeking to stop the mass closing of public schools and their replacement by corporate-driven, privately-operated charters and voucher schools. It includes, not just representatives of Newark, but also groups representing parents in Camden, Jersey City, and Paterson, like Newark, state-operated school districts that have tried to force school privatization on unwilling parents.
Smith says she expects the federal investigation to focus on three schools in Newark–Hawthorne Avenue, Bragaw Avenue, and Roseville Avenue. Cami Anderson, the state-imposed schools superintendent in Newark, has concentrated on schools in the city’s South Ward.
Anderson has a special relationship with leaders of TEAM Academy Charter Schools and had hoped to turn virtually the entire South Ward over to the privately-operated charter school, part of the national KIPP charter school chain.
Parent activists–especially at Hawthorne–have worked against Anderson’s plans. Its principal, H. Grady James, has so far refused to apply for his own job at Hawthorne, contending the school–the highest achieving elementary school in the district–doess not need to be subjected to Anderson’s renewal plans.
Title Six of the Civil Rights act forbids any agency receiving federal funds–and the Newark schools receive federal funds–from discriminating on the basis of race. The federal government’s website explains:
“If a recipient of federal assistance is found to have discriminated and voluntary compliance cannot be achieved, the federal agency providing the assistance should either initiate fund termination proceedings or refer the matter to the Department of Justice for appropriate legal action. Aggrieved individuals may file administrative complaints with the federal agency that provides funds to a recipient, or the individuals may file suit for appropriate relief in federal court. Title VI itself prohibits intentional discrimination. However, most funding agencies have regulations implementing Title VI that prohibit recipient practices that have the effect of discrimination on the basis of race, color, or national origin.”
PULSENJ–“Parents Unified for Local School Education”–has been working quietly “in the background,” says Smith, as parents in Newark protested Anderson’s plans–backed by Gov. Chris Christie–to privatize Newark schools.
“We were looking for the appropriate legal action to show that the plan discriminated against people of color,” she said.
PULSENJ filed the complaint against “One Newark” May 13, as part of its commemoration of the 6oth anniversary of the Brown vs. Board of Education ruling that outlawed school segregation. The organization wrote:
In a letter to Holder and Education Secretary Arne Duncan, the organizations ask for an immediate investigation.
“Education ‘reformers’ and privatizers are targeting neighborhood schools filled with children of color, and leaving behind devastation. By stealth, seizure, and sabotage, these corporate profiteers are closing and privatizing our schools, keeping public education for children of color, not only separate, not only unequal, but increasingly not public at all.”
Jitu Brown explained that federal education law encouraged discrimination and privatization by allowing the privatization of public schools as a consequence of school failure. Journey for Justice, the umbrella organization he heads, persuaded the federal government to add yet anther possible outcome of school failure–“sustainable school transformation,” the replacement of failing public schools with community schools that have adequate resources to ensure student success.
Brown says he hopes a a finding of discrimination will allow the development of community schools based on that model.
“What has been lacking–not only in Newark, but also in places like Chicago, New York, and New Orleans–is community input to help develop plans for successful public schools. We have been faced with top-down education policies that have failed because they lack input from the people who are most affected,” says Brown.
This is true not only in Newark, Brown says, but also in Chicago, New York, and Washington, DC.
Brown pointed out the reforms in these towns have been based, not on providing resources to the schools, but on opening up private markets to entrepreneurs.
“The programs are test driven and narrow,” says Brown. “Teachers don’t receive the resources they need. Kids are treated like criminals. If parents complain they don’t receive the wrap-around services their children need, they are accused of stealing.”


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- Epic Riff: Just about all of their songs, though "Just Like You," "Pain," "Animal I Have Become," and "Break" stand out.
- Face of the Band: Adam, of course, which the label and/or manager seems to be aware of.
- Fan Vid: A popular target of them.
- Fridge Brilliance: "Pain" could be taken as either wangsty, vaguely masochistic or Word Salad. Taken in the context of Adam's painkiller addiction, the lyric "I'd rather feel pain than nothing at all" takes on a new light...
- Nightmare Fuel: Music Videos
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The history of submarine operations during the Cold War has by now been told many ways, but typically from the American point of view. Cold War Command: The Dramatic Story of a Nuclear Submariner adds an important dimension to this literature by coming at the confrontation between Soviet and Western submarine forces from the perspective of the Royal Navy. Despite the title, Cold War Command is less a dramatic story of nuclear submarine operations and more a narrative of Captain Dan Conley's career as a Royal Navy submariner against the backdrop of the Cold War, including some nuclear but also diesel submarine operations. Written with Captain Richard Woodman, a distinguished maritime historian, the book offers an effective telling of the waxing and waning in importance of the Royal Navy's submarine flotilla during the Cold War, including details such as the challenges associated with shipbuilding, maintenance, and weapons effectiveness, which are...
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July 01 2015
Cold War Command: The Dramatic Story of a Nuclear Submariner
Cold War Command: The Dramatic Story of a Nuclear Submariner.
Timothy J. Galpin
Johns Hopkins University Applied Physics Laboratory
Online ISSN: 1531-3298
Print ISSN: 1520-3972
© 2015 by the President and Fellows of Harvard College and the Massachusetts Institute of Technology
Massachusetts Institute of Technology
Journal of Cold War Studies (2015) 17 (3): 287–289.
Timothy J. Galpin; Cold War Command: The Dramatic Story of a Nuclear Submariner. Journal of Cold War Studies 2015; 17 (3): 287–289. doi: https://doi.org/10.1162/JCWS_r_00554
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Transportation Solutions for Students
FAU received a $375,000 implementation and research grant from The Kresge Foundation to identify, address and evaluate transportation solutions for students.
The FAU team published a white paper describing the project activities to date: development and pilot testing of the research protocol and design and first stage development of the MaaS mobile app (Read the white paper).
On December 18, 2019, FAU’s Center for Urban and Environmental Solutions kicked off the collaboration with two area colleges and three transit agencies: Broward College, Palm Beach State College, the South Florida Regional Transportation Authority (SFRTA, which operates Tri-Rail), Palm Tran, and Broward County Transit. The newly formed Transit Partnership met at the FAU Boca Raton Campus to align goals and opportunities.
Local students who use transit often face lengthy travel and wait times due to inadequate bus and train schedules, while many more students who buy vehicles spend their limited incomes on car payments, gas, insurance and vehicle maintenance in a highly congested region. Of the 140,000 students at the three participating institutions, more than 40% received Pell grants, and more than 50% are students of color.
With its partners, FAU will first engage a transit app firm to customize a mobile app that helps users overcome the fragmented public transit system by recommending trip plans that combine real-time data on all existing modes of transit (buses, trains, walking, biking and Uber/Lyft). A second phase will layer in new transit options, such as new shuttle schedules and electric scooters, to address identified gaps in the transportation ecosystem. FAU transit researchers will examine the effects of the app and any new transit solutions on students’ commuting behavior and on access and success in higher education.
As one of two implementation and research grants, FAU stood out because of its ambitious scale in terms of the number of students served and the multi-city, multi-agencies collaboration and the innovative transit solutions. In addition, if proven effective, the partners plan to sustain and scale the transit solutions through a mix of institutional support and public dollars from a new sales tax dedicated to transportation solutions. In addition, because the FAU project leaders are transit, not higher education, experts, their publications will introduce to the transit field the idea that transit solutions may affect student success.


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Donald Trump is in the United Kingdom. The Trump baby balloon has taken to the skies once more and thousands of us have take to the streets to protest the racist, sexist, homophobic, transphobic, ant-Semitic, Islamophobic, orange fascist who currently dominates world news with his nonsensical Twitter feed, criminal activities and constant stream of bigoted, hurtful policies.
In March, I walked through London with a million other people to protest another massive blunder, the UK’s upcoming exit from the European Union. That protest was much larger but also much more upbeat. Yes, we were protesting, we were scared of our post-Brexit future and we were massively angry at the incompetence of our government, but there still managed to be something lighthearted about it all, a sense that we were doing something powerful and almost un-British by marching in droves and kicking up a fuss.
Today was different.
The Trump protest was angry. Of course it was. The most powerful man on the planet, the leader of the free world, is a fascist, plain and simple. He has locked children in cages, banned abortion in parts of the US and placed a travel ban on primarily Muslim countries. He has lied and committed crimes. He has done things that many historians and sociologists have made clear are not the start of a murderous regime, but several steps along the way. And we, a nation that, in theory, aims to be open, tolerant and accepting of the many wonderful and diverse forms humans take, have rolled out a red carpet and baked scones while Trump meets the queen and poses with our disgraced prime minister.
It is a fucking abomination that this orange-faced idiot is welcomed with respect and admiration while we let innocent people die at sea instead of trying to welcome them onto our shores. Trump is not only hurtful, frustrating and embarrassing, he is also dangerous to people of a myriad of different identities across the USA and the world. Trump poses a threat to women, people of colour, poor people, LGBTQ+ individuals, disabled people, immigrants, Jews, Muslims and more – with this risk multiplied for people who fall into a number of these categories, of which there are many. In fact, while marginalised groups are even more at risk under the Trump administration, the truth is that he poses a risk to almost everyone, through his denial of the climate crisis, attacks on healthcare and general disregard for other people’s quality of life.
I despise Donald Trump for so many reasons. I despite him because he bragged openly about sexually assaulting women; because he is trying to limit access to abortion; because he doesn’t believe in climate change; because he called other, poorer countries ‘shitholes’; because he lies, constantly; because he has banned trans people from serving in the military; because he put a travel ban on Muslim countries; because of his racist statements and refusal to engage with all the ways in which black people are discriminated against in the USA and the world; because of his censorship of science; because he put children in cages, some of whom have died; because of the way he stokes hatred and fear about immigrants; because he refuses to condemn gun violence; because he doesn’t brand white shooters as terrorists; because he mocked a disabled reporter; because he is totally, completely, unequivocally unqualified to be occupying the world’s highest political office; because he is a criminal but no one will impeach him; because he pulled out of the Paris Agreement; because he called London’s mayor a ‘stone cold loser’; because he endorses Nigel Farage and Boris Johnson; because he still wants to build that fucking wall; because he doesn’t believe that healthcare is a human right; because he released a video interspersing clips of Muslim Congresswoman Ilhan Omar with footage of 9/11 to incite Islamophobic violence; because he endorsed Brett Kavanaugh for the Supreme Court; because he derails any legitimate criticism or questions with calls of fake news; because he has turned global politics into a farce; because his administration renewed the contracts for for-profit prisons; because in 2017 he boosted funding for the military at the expense of science, education and healthcare and because of all the other terrible, depraved, illegal, traumatic and otherwise despicable things he has done during his presidency (and before that).
He is a truly reprehensible human being and I, along with thousands of other people, are tired of having to explain why to those who apparently can’t see what’s right in front of their eyes.
We are tired of the fear and apathy that comes with these administrations. We are tired of making space and excuses for bigoted bullies whose sole aim is to control, subjugate and harm those around them. We are tired of people who refuse to grant personhood to the people they share their community with, but will fervently demand that a ball of cells be given greater autonomy than human women.
And we are fucked off that this man has been given a platform in the UK, as if he has any interest in diplomacy or trade or foreign policy instead of just wanting to mooch around causing offence and making a mess.
I felt that today. It was heartwarming to see such a diverse set of people protesting together, chanting and marching and demanding a better future for themselves and those around them. There were brawls with the police and fights broke out between protestors and the Trump supporters who’d come along to be inflammatory. There was anger and frustration, understandably, but there was also hope. There was the unspoken solidarity that at a time when so many are at odds, you can look at someone’s sign or hear their chant and know that you are among friends.
There were some beautifully creative signs at the protest today, along with riotous speeches and stirring chants. I loved seeing people with their kids, showing their children that this what you do when you want to make change. While Brexit drags on and Trump’s continued presence in the White House makes us painfully aware of the threat of nuclear war, it is always empowering to stand amongst a crowd of people and speak with one voice. Today, that voice shouted a resounding “fuck you, Trump!”


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Looks like you’re next visit will be to Chattanooga, TN based on your answers to our city quiz
Welcome to Chattanooga — the Scenic City, Gig City + River City, all in one. Chloé and Trista here, the editors of NOOGAtoday, and we’re so excited to show you around. Before we get started on the tour, here are a few Nooga facts:
○ In 1815, John Ross settled the area, called Ross’s Landing at that point, and renamed Chattanooga in 1838. The name came from a Creek Native American tribe word meaning “rock rising to a point.”
○ Now, Chattanooga’s most popular nickname is Scenic City. It’s not hard to understand why — Nooga has the most stunning landscapes in the state. It’s surrounded by mountains + ridges, with the Tennessee River flowing through.
○ Chattanooga is in one of the most biologically diverse areas of the world. Yeah, we said world. The city is in a temperate moist forest biome and holds multiple ecosystems. The waterways that run through boast a rich freshwater life, and beyond the surface, there’s an underwater rainforest.
Alright, let’s have a look around.
Visit now: The Tennessee Aquarium has live cams of their penguins, sharks + otters. They also do a virtual Facebook Live event every day at 1 p.m., and you can catch their past #AquariumAtHome videos here.
Visit later: When the aquarium opens back up, don’t miss the magical butterfly exhibit. 🦋 Oh, and while wandering down Discovery Hall, keep your eyes peeled for the country’s largest salamander — the hellbender — which breathes through its skin.
Bonus: The Tennessee Aquarium has been rated as Chattanooga’s top attraction, and if that’s not enough, it was ranked in the top 10 aquariums in the world.
Visit now: It’s hard to even know where to start — the Hunter Museum has truly built a virtual experience to enjoy while we’re sheltering at home. There’s everything from kid’s activities — wanna do a photo scavenger hunt, anyone? — to the permanent art collection and mini-concerts from String Theory.
Bonus: Trista here, and my personal favorite exhibit was “Southbound: Photographs of and about the New South.” It left the Hunter on April 26, but you can still experience it virtually.
Visit later: When the museum reopens, check out one of their educational programs. They have something for everyone, pre-K to adults.
Visit now: Go behind the scenes of this famous underground waterfall — it’s the tallest and deepest one open to the public in the U.S. — with Facebook Live tours. They have tranquil escapes with soothing sounds and visuals, educational talks about geological formations, stories of historical moments at the falls + more.
Visit later: As fun as a virtual tour is, there’s nothing like plummeting six stories by elevator into a cave. And if you’re a thrill-seeker, you have to try the High Point ZIP Adventure — the views are breathtaking, and you can do some rock climbing, too. (Like a true Noogan. 😅)
Visit now: There is so much to learn from this level 4 arboretum and nature center, and luckily they’ve been keeping us on our toes with educational videos about local wildlife. Fill your head with facts about red wolves, which trees grow best in certain climates and the history of bird-banding + why it’s rapidly changing. No matter where you live, the folks at Reflection Riding are on a mission to make you a steward of your natural surroundings.
Visit later: Rent a canoe and tour Lookout Creek — there is a gentle current and beautiful scenery, so it’s nothing short of relaxing. You also cannot miss the native animal exhibit. All animals at this nature center have either suffered an injury, been kept illegally as a pet or are endangered and part of a species survival plan. We highly recommend checking out the red wolves.
DYK — the red wolf has been endangered since 1967. According to the United States Fish & Wildlife Service, there are only about 40 living in native habitats in eastern North Carolina and more than 200 are in captive breeding facilities throughout the U.S.
Eatin’ in NOOGA
When it’s safe to visit, you’ll have plenty of delectable food options.
We’ve also got plenty of articles to help you navigate the local food scene.
○ You can’t miss these classic Chattanooga restaurants, like Tremont Tavern, River Street Deli + Lupi’s Pizza.
○ There’s no better way to find good food than to ask the locals. Here you can see what local foods Chattanooga residents can’t live without.
○ And if you’re gluten-free, we’ve got you covered there too. Check out this list of 20 local restaurants with gluten-free options.
○ If you come to town and get the urge to cook, you may want to check out these places to get local produce.
That brings us to the end of the tour. You didn’t think we could show you all of Chattanooga, did ya? Some things you just have to experience in person, like paddleboarding on the river on a sunny day or hiking to Sunset Rock for a picnic + views.
If you still haven’t had enough of Nooga, check out the photo album we recently made and start daydreaming about which local hostel + hotel you’ll stay when you visit. And be sure to stop by the Chattanooga Tourism Co. website for more virtual fun + inspiration for your next trip to Scenic City. We can’t wait to see you. 👋


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Facebook has often found itself the center of scrutiny what it does with user information, and has faced direct consumer calls for stronger security as well as questions from Congress. Users have complained that the former document was impossible to interpret without a lawyer, and Facebook is directly acknowledging this. “We agree that privacy policies can and should be more easily understood, and that inspired us to try something different.” And while Facebook hasn’t amended its policy, it breaks down exactly how it accumulates user data and where it goes from there.
This is currently a work in process, and one that hasn’t been officially adopted as part of the permanent Facebook handbook. It’s admittedly more user friendly, but something tells us Facebook is going to continue to find itself mired in privacy concerns. But now its accusers will be better informed.
- How to delete or deactivate your Facebook account
- Facebook Messenger finally starts testing end-to-end encryption for all chats
- Targeted Facebook ads are about to lose a big audience: iPhone owners
- Facebook says iOS 14’s new privacy tools could harm its ad business


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Mens Leggings & Meggings | Mens Compression Pants
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Tired of the same, old sweatpants? If you’re looking for the most modern workout pants, then you need to give meggings a shot. If you’ve never heard of meggings before, it’s just a shortened term for mens leggings (aka: male leggings). You probably also know these leggings for men as: mens compression pants, running tights or athletic tights. They’re designed in super stretchy, sweat-wicking spandex blends that’ll complement virtually any physical activity – weightlifting, running, dancing to cycling. Our men’s athletic tights aren’t just for pumping iron. You can actually improve your muscle tone in a flash with our muscle-enhancing line of mens compression pants by Maskulo. On top of mens workout leggings, we’re also stocked with the latest styles in mens fashion leggings that look just as trendy with casual streetwear. Check out our diverse collection of men’s leggings designed in solid colors, metallic sheens and standout patterns. From patriotic flags to military camo, you’ll definitely find the ultimate mens leggings to boost your activewear game.
If you’ve never tried on mens leggings before, you’re probably wondering what to wear with them. You can actually style mens workout leggings or compression tights the same way you’d style skinny sweatpants. Since men’s leggings fit like a second skin, it’s really about balancing your outfit with the right tops. For guys that want to wear mens compression pants purely for exercising, you can wear them with pretty much any graphic hoodie, tee or tank. On the other hand, when you’re styling mens fashion leggings, don’t be afraid to kick it up a notch. These fashionable tights for men look even better paired with combat boots, longline tees and bomber jackets. Whether you’re working on your triceps or your gym-selfie game, our cool leggings and meggings will keep every early riser and hardcore athlete motivated to get fit.

domain: sports


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Journal: Annales Academiae Medicae Stetinensis. 2006;52 Suppl 2:105-10.
Authors and affiliation: Atarowska M, Samborski W. Klinika Fizjoterapii Reumatologii i Rehabilitacji Akademii Medycznej im. K. Marcinkowskiego ul. 28 Czerwca 1956 roku 135/147, 61-545 Poznan.
Purpose: We present a case of a 33-year-old woman with nonspecific systemic symptoms (fatigue, weakness), widespread pains, sleep disorders, morning stiffness, accompanied by symptoms from the autonomic nervous system (chest pain, digestive tract disorders, hyperesthesia of the skin, dizziness, paresthesia with a feeling of coldness in hands and feet, excessive sweating, breath problems, palpitations).
The diagnostic process was difficult and it took a long time to establish the diagnosis partly because of problems in cooperating with this patient. During several years, the woman was hospitalized at several specialist departments, underwent many consultations, laboratory tests, and imaging studies.
Finally, Fibromyalgia was diagnosed.
Conclusions: Treatment was implemented with good results improving the quality of life of this patient.

domain: health


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Spoken Word Cabaret – New Mills Festival 2018 – Friday, 14th September
Excited to be part of the fabulous Festival Fringe launch night, brought to you by New Mills Festival and Write and Release Poetry. This is a not-to-be-missed night of brilliant spoken word performances featuring authors from High Peak, Greater Manchester, and beyond.
The Spoken Word Cabaret will feature a full range of spoken word performers ranging from the humorous to the poignant. Come hear a diverse group of poets, novelists, dramatists, and folklorists all set to make you laugh, cry, and contemplate the unfathomable.
Tickets £5 (includes free glass of wine) from Priscilla’s Hallmark, Market Street, SK22 4AA or online HERE
“Another exciting Author Event to look forward to on Tuesday 19th July.Margaret Holbrook, Pamela Turton and Mark Henderson will be entertaining us with readings from their books. Come along and join us for this free event. Tea and biscuits will be served.”
Disley Library Off Buxton Old Road Disley Stockport Cheshire SK12 2BB (Location Map)
Three local authors between them have something for everyone. Let Margaret Holbrook, Mark Henderson and Pamela Turton entertain you with stories and extracts from their range of traditional and contemporary writings.
Each of the authors will be reading from their work, for about 20 minutes each (with drinkies break) followed by a Q&A session. So get those questions ready! Mark is a natural storyteller and will read from his latest ‘Folktales of the Peak District’. Margaret has written several books of poems/stories; her latest is ‘Hobby Horses Will Dance’. Pamela has also published poetry and novels. She’ll be giving you a taster of her 4th novel, due out this August too.
Merry Month of May Theme – Open Mic Event
Saturday 28th May, 10.30am – 12.30pm
Tomorrow, come and share readings, or just to listen, about the inspiring month of May. I’ll be reading a scene from my fourth novel (which I’m currently editing- bit of a slog – hoping to launch this summer!)
If you are starting out or are a seasoned performer, come along and read your own work, or those of other writers, in a very encouraging atmosphere. Bring something on the theme of May, or any work of your own choice. Ideas and suggestions around the month of May included: Merry Month of May, Maypole, May Day, May Flower, Whit Walks and Brass Bands. All welcome!


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Srinagar: At least three top leaders of the Peoples Democratic Party (PDP) are hobnobbing with the BJP with an aim to divide the party and continue the alliance in case of a break-up. The old guard of the PDP feel left out as they think a few youngsters are running the party, The Indian Express reported on Wednesday.
The partys leadership, the report said, is looking at ways to keep the alliance afloat and stay in power because other options appear to be running out. Plunging the party into a deeper crisis is the Chief Minister Mehbooba Muftis unproductive meeting with the Prime Minister Narendra Modi. The PM Modi has rebuffed her proposal for a dialogue with stakeholders in the Valley.
There is a sense (in the party) that the alliance may not survive for long but most leaders feel that an immediate break-up will be suicidal. If we lose power right now, our condition will be worse than the Jamaat (e-Islami) workers after the Bhutto hanging in 1979, a PDP leader is quoted to have said, referring to the anti-Jamaat riots in the Valley after the hanging of Zulfiqar Ali Bhutto. No one disagrees with the mood on the ground.
Several PDP leaders and Mehbooba Mufti loyalists have expressed fears of a split in the party. We know that it doesnt suit the BJP to dismiss the government and impose Governors rule. They wont break the alliance too. We have our own calculation, one of the leaders said. If they break the alliance, the BJP wont be in power in the state for a long time because they wont find partners. We apprehend they will instead split our party and continue an alliance.
The leader said the only hope is that we (PDP) manage to reclaim our narrative before a break-up with the BJP a break-up has to happen on our terms. Thats the only way we will stay in the game. Thats perhaps the only way for the entire mainstream to survive. Several PDP leaders told The Indian Express that on the ground, people including supporters feel the party has completely surrendered before the BJP.
The leader further said the PDP has decided to become more vocal on issues, start talking about self-rule, demilitarisation etc again and hope that the insistence on implementation of the agenda of alliance and situation on ground will shift before a break-up.
Another PDP leader said the current situation in Kashmir will only impact the PDP. The BJP isnt affected. In fact, they want harsher measures to control the situation because that suits them politically, the leader said, adding we are in serious trouble
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domain: politics