MUMBAI: Move Networks, a provider of online television services, announced at the MIX08 Conference plans to partner closely with Microsoft to enable Move Networks’ high quality video streaming technology within Microsoft Silverlight.
Microsoft Silverlight, a cross-browser, multiplatform plug-in for delivering the next generation of media experiences and rich interactive applications for the Web, will soon support Move Networks’ video streaming technology that allows for fast start times, smooth playback with no buffering, and high quality video resolution. The Move Media Player is currently used to deliver HD video content online by leading media companies such as ABC, the CW, Discovery Communications, ESPN, Fox, Warner Brothers, and many others.
As online video viewing continues to grow exponentially, Move Networks’ technology combined with Microsoft Silverlight’s open, flexible platform will give media companies and developers the ability to quickly deploy unique online television offerings. Within one environment, developers will be able to seamlessly provide unique branding and navigational elements within, around and on top of the highest quality online video on the Internet.
"Silverlight is focused on delivering the most flexible cross-platform development environment for creating rich applications online," said Microsoft Corp general manager in the developer division John Case. "The era of static web pages is well behind us. Media companies are intent on delivering video-rich, interactive experiences for users. Working together enables us to offer those media companies Move Networks’ video streaming technology within the flexible Silverlight development platform."
"Across the board, media companies are looking for smart, seamless ways to maximize the advertising opportunities of their online television content," said Move Networks CEO John Edwards. "Move has specialized in driving higher viewership through better quality of experience. By partnering with Microsoft, we’re offering the most flexible, creative platform for creating the best video and navigation experience for online television."
Utilizing Move Networks’ video streaming within Silverlight’s development platform will allow media companies and advertising agencies to unleash their creativity in developing new, interactive advertising elements for online video.
Web users will also benefit from the single, open development environment that will come from Move Networks’ relationship with Microsoft. When users view online video, they’re looking for a high quality experience. The combined Silverlight and Move Networks solution will enable media companies to more easily develop the best viewer experience with both rich navigation and high quality video.


CPT LAB COLUMN FLOTATION CELL back to SUBCATEGORY. Category: ASSAY LAB EQUIPMENT. SubCategory: FLOTATION. Type: COLUMN FLOTATION. Manufacturer: CPT. Qty: 1. Location: SAVONA, BC CANADA ... Nelson Machinery Equipment Ltd. PO Box 180 6451 Trans Canada Hwy. #1 West. Savona, BC Canada V0K 2J0.
♦ Simple measures can be adopted to prolong column lifetime ♦ Regular performance tests to monitor any deterioration ♦ Select the column most suitable for your application ♦ Consider all operational variables the column is not always the problem Conclusion
Jet diffuser flotation column (JDFC) is a flotation device resembles Jameson flotation cell (JFC) in terms of operational principles, but it has significant difference structural points of view.
Slurry bubble columns are generally used in industries as multiphase contactors. Flotation column is one such equipment where solidsolid separation is achieved by the rising air bubbles in a slurry medium. Flotation column offers several advantages over conventional mechanical flotation cells .
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Deister Flotaire Column Flotation Cell built for coarse coal flotation was commissioned in 1986 in a coal preparation plant in Pennsylvania. This unit was installed to improve the recovery of mm (28 mesh) coal which was being lost to the tailings in the plant's existing mechanical flotation cells.
NOVEL VERTICAL COLUMN FLOTATION DESIGN FOR GULF OF MEXICO DEEPWATER FLOATING STRUCTURES. Kevin A. Juniel, Dr. Ted Frankiewicz, Dr. ChangMing Lee – NATCO Group, Inc. I. Introduction And Background. Oilfield operating companies in the Gulf of Mexico (GoM) continue moving to ever increasing water depths to produce oil and gas reserves.
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However, in column flotation, there is no mechanical mechanism causing agitation. As well, separation takes place in a vessel (known as a column) that is much taller than the width (or crosssection) of the cell. Air is introduced into the slurry in the column through spargers, which .
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Flotation test were operated in a laboratory flotation cell with 50 milliliter cell volume. In a typical flotation test, the weight of a representative sample is 5 g. They followed the flow sheet in Figure 1. Pulp density was adjusted to 10% solids by volume at each test. All reagents were of technical grade.
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Sanofi-Aventis' TB Drug Rifapentine Receives Orphan Drug Status In EU - Update
(RTTNews) - French drug maker Sanofi-Aventis SA (SNY) said Thursday that the European Commission has granted Orphan Drug status for rifapentine for the treatment of tuberculosis or TB.
Rifapentine is a member of the rifamycin class of antibiotics. It is a rifamycin derivative with a higher inhibitory activity against M. tuberculosis and a longer half-life than rifampin. These properties are expected to improve drug exposure and potentially lead to a better efficacy.
Rifapentine's Orphan Drug designation confers several benefits to drug development, including protocol assistance provided by the EMA throughout the drug development process, direct access to the European centralized procedure to register the medicinal product in Europe, reduced fees for filing drug approval and marketing exclusivity in the approved orphan indication for a period of 10 years in the European market.
The EU grants Orphan Drug status to medicines intended for treatment of life-threatening or chronically debilitating pathologies that affect no more than 5 in 10,000 people in the European community.
Tuberculosis describes a broad range of clinical illnesses caused by the bacteria Mycobacterium tuberculosis. World's 30% population is infected with M. tuberculosis, and around 9.8 million people develop active disease annually. Of these, 1.7 million die each year.
The Orphan drug status was based on the recommendation that rifapentine-based combination regimen may be of significant clinical benefit for drug-susceptible TB patients by shortening their tuberculosis treatment. This positive opinion was released by the Committee for Orphan Medicinal Products or COMP of the European Medicines Agency or EMA.
Rifapentine is currently marketed in the U.S., commercially known as Priftin, for the treatment of pulmonary and drug-susceptible TB in combination with other anti-TB drugs, within a standard 6-month course. In 2008, 12,904 TB cases, which correspond to a rate of 4.2 cases per 100,000 persons, were reported in the United States.
Sanofi-aventis noted that it is revisiting the development of rifapentine to be given daily, in combination with standard daily companion drugs. This aims to significantly shorten the duration of drug-susceptible TB treatment. This should lead to less premature cessations of treatment, and thus to a reduction of treatment failures, a lesser risk of development of drug-resistance, as well as a reduction of costs, all of which are expected to bring significant benefits to patients and public health systems.
SNY finished Wednesday's regular trade at $30.06, on the NYSE.

domain: medical


For those who come to the city of Camagüey, their visit is almost mandatory, for those of us who love this princely city it is the perfect place where we delight ourselves with a unique framework.
And it is that the Plaza del Carmen, in addition to being one of the best-preserved urban settings in terms of architecture, is a beautiful place full of traditions, culture and Cubanness.
The sculptural figures of the renowned Camagüey artist Martha Jiménez give it a stamp of originality and it is one of the places that gathers the largest audience in search of authentic and Creole photographs.
Talking with the gossipers, sitting in the empty chair and making a wish, trying to decipher what the newspaper says or dreaming about the love professed by the lovers there, is the atmosphere that recreates a square that is steeped in customs and a lot of history. (Dayessi García Sosa / Radio Cadena Agramonte) (Photos: Humberto Cid / Radio Cadena Agramonte)


Cyber safety talks urged
Updated: 2015-08-04 05:17
By CAO YIN in Beijing and CHEN WEIHUA in Washington(China Daily USA)
Experts call US plan to damage firewall 'dangerous'
The best way to solve cyber-security problems between China and the United States is through communication and negotiation, instead of engaging in a war of words and threats, Chinese Internet specialists said on Monday.
The New York Times reported over the weekend that the US government had studied several plans to retaliate against those suspected of stealing the personal information of about 20 million US citizens, such as damaging the attackers' network firewall.
Although the US has not given a clear reply on which country it believes was the online attacker, the officials involved in the investigation, including James Clapper, the US national intelligence director, said that the biggest suspect is China, according to The Times.
The report quickly stirred up a debate between the two nations and attracted the attention of experts in the online security industry.
Shen Yi, deputy director of the Internet governance research center at Fudan University, said that unreasonable accusations or online battles will not solve the problem. The reported plan to damage the attackers' firewall means the US aims to destroy China’s network infrastructure, "which is dangerous and serious."
"The two countries should first figure out whether the attack was from China, and then sit down for communication instead of arguments," Shen said.
Guessing who is responsible will aggravate the security problem between the nations and may cause the US to exercise bad judgment, according to Shen.
Zuo Xiaodong, vice-president of the China Information Security Research Institute, said that for the US to make accusations without evidence was irresponsible.
"The US ignored communication channels that the two countries built to solve security problems, which will make future security cases more serious and lead the two sides into a cold war in cyberspace," Zuo said.
Zuo highlighted the complexity of each security case, saying that China suffers online threats from around the world.
For example, more than 80 percent of government websites have been attacked, according to the National Computer Network Emergency Response Technical Team.
"What the two countries should do is stop irresponsibly blaming the online attacks on each other. Instead, we should better share security information and tackle cases via our established communication platforms," Zuo said.
Richard Bush, a senior fellow at the John L. Thornton China Center of the Brookings Institution, said there may be opportunities in the cyber area for the two countries to deal with during President Xi Jinping’s state visit to the US in September.
Bush said the two countries tend to agree at the top that certain aspects of the cyber domain are off limits. "Critical infrastructure seems to be one, where there is a mutual interest that neither side will attack the other. Can that sort of thing be pursued in a way that increases mutual confidence and allows for proper monitoring?" he said in a Brookings talk last Wednesday.
In a letter published in the Washington Post last Thursday, Zhu Haiquan, spokesman of the Chinese embassy in Washington, repeated the stance that the Chinese government firmly opposes and combats all forms of cyber attacks in accordance with Chinese laws and regulations.
Zhu said cyber attacks across borders are very complex and hard to trace. Therefore, combating such activities requires closer international cooperation and formulating international rules and norms to govern behavior in cyberspace.
"This is where the interests of China and the United States align. We can accomplish much more by working together than apart," he said.
Many Chinese have felt that the revelations made by Edward Snowden, a US National Security Agency contractor, have clearly shown that the US has been using its mighty cyber capability to penetrate the networks of governments, universities and corporations.
Such concerns are shared by many other countries, including many US allies. Last Friday, the WikiLeaks website showed evidence that the NSA has been conducting a wide-range of espionage operations in Japan, targeting Prime Minister Shinzo Abe and other top government officials and major corporations, as well as trade negotiation and climate strategy information.
"Making unfounded accusations and resorting to megaphone diplomacy is counterproductive. And there is no place in this solution for double standards," Zhu said.
Contact the writers at email@example.com, firstname.lastname@example.org
- Tsingtao gets ready for huge beer festival in China
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- A glimpse of Chinese cultural relics in foreign museums
- Flying Tigers show in New York
- Kobe Bryant frenzy grips Guangzhou
- Three generations keep traditional lion dance alive
Seventh China-US strategic dialogue
Premier Li embarks on Latin America visit
What do we know about AIIB
Full coverage of Boao Forum for Asia
Annual legislative and political advisory sessions
Spring Festival trends reflect a changing China
Today's Top News
Obama issues challenge on climate change
GOPs begin pivotal debate week
Negotiation seen as key to China, US cyber solution
Beijing plans 'Silicon Valley' park for traditional culture
Obama issues challenge on climate change with power plant rule
China role crucial in UN plan
Biden associates resume discussion about presidential run
Malaysia seeks help to widen search for MH370
Geared to go
The place to be


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NexTech AR Solutions (NexTech) (OTCQB: NEXCF) (CSE: NTAR) (FSE: N29), an emerging leader in augmented reality for eCommerce, AR learning applications, AR-enhanced video conferencing and virtual events is pleased to announce NexTech is now an approved Microsoft partner creating enormous new business opportunity for the company. This partnership provides access to the Azure Marketplace so that InfernoAR can be sold directly through the Marketplace.
The company is also working to become part of the Microsoft cross sell program where Microsoft’s sales reps will sell InfernoAR and be incentivized to do so by the Microsoft reps getting Azure sales credits whenever they sell the InfernoAR product.
Nextech is currently building new video conferencing features which will integrate collaborative classroom learning, one to one networking and traditional video conferencing directly into the InfernoAR platform letting users seamlessly launch and manage both collaborative experiences and large audience events directly from InfernoAR, once this is built it will be offered online in Azure. The company is also planning to move InfenroAR into Azure.
“With this Microsoft partner program NexTech AR continues to build momentum as it scales up customer wins and is at the forefront of making video conferencing and AR easy to implement and quickly accessible to everyone,” states Evan Gappelberg, CEO of NexTech AR.“NexTech’s industry-leading InfernoAR platform and end-to-end augmented reality solution along with our partnership with Microsoft and it’s huge unparalleled ecosystem brings Nextech AR deeper into the technology marketplace then ever before and provides us with an enormous opportunity for more customer wins.” […]

domain: news


Tortuous negotiations on who will fill key posts in the new centre-right cabinet appear to have ended in agreement, with the final pieces of the jigsaw falling into place for new prime minister Petr Nečas. His Civic Democrats seem to have made considerable concessions, with the powerful ministries of finance, foreign affairs and the interior all going to smaller coalition allies. But surprisingly – and for the first time in eight years – there’s not a single woman amongst them.
Petr Nečas now has what looks like a cabinet, after eight hours of talks with his coalition allies – the right-wing TOP09 and the centrist Public Affairs. TOP09’s Miroslav Kalousek will get the finance ministry, the party’s leader Karel Schwarzenberg will become the next foreign minister, and most controversially, Radek John, the politically inexperienced leader of the Public Affairs party, will become interior minister, despite repeated concerns from Mr Nečas about Public Affairs’ links with the private security firm that sponsors it.
The Civic Democrats’ key portfolios will be industry and defence, although as Mr Schwarzenberg pointed out, it is TOP09 who will carry the greatest burden, as they’ll be in charge of health and social affairs, where unpopular cuts are expected.
But there was dismay for those campaigning for greater involvement of women in Czech politics, after not one post was given to a woman,for the first time in any Czech cabinet since 2002, and despite the record number of newly-elected women MPs. Jana Ciglerová writes about women’s issues for the newspaper Mladá Fronta Dnes:
“It’s an absolute slap in the face I have to say, after all those headlines we saw after the elections that women are now leaders of the Czech Republic. To have a government that has absolutely no women in it is shocking. It’s the third millennium, and yet half of the population is still not represented in the government. It’s appalling.”
Public Affairs leader Radek John was quoted as saying that there are no women in the government because they were put off because the coalition negotiations were so tough. What do you think of that?
“Radek John has by his side one of the most politically educated people on the Czech political scene [the party's programme manager Kristýna Kočí]. She is more ready for tough negotiations - and for leading - than he is. To say something like that when he has had a woman by his side all during the negotiations is…shocking. I’m sorry, I’m lost for words. It’s shocking.”
All three parties have expressed regret about the lack of female ministers, and some political analysts say they might indeed live to regret it. Certainly it’s a striking contrast with neighbouring Slovakia, a country about to get its first female prime minister.
Czech government reopens borders sooner than planned, special regime with Slovakia
Official: Covid-19 not primary cause of death in 60 percent of those who have died with disease
Prague City Tourism shifts the focus to domestic tourists
“We wanted to do something beautiful” - How the US cavalry saved some of world’s most treasured horses in wartime Czechoslovakia
Czech Republic ready to “normalize” travel with twenty European countries


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Blake Shelton Says Miranda Lambert “Would Never Want to Tame Me”
Check out the February issue of REDBOOK magazine that features Blake Shelton on the cover!
Blake speaks about how Miranda doesn't want to change him and he doesn't want to change her.
Blake also shared his secrets to being a good hubby.
"I think you've got to be confident and a little bit of a pushover," Blake told Redbook. "Obviously, you've got to be a loyal person. I'm never going to listen to someone trash my wife. I think you have to be willing to take a bullet for somebody if you're going to stand up there, take your vows, and be married to them for the rest of your life."
Source: US Weekly/Red Book Magazine/Warner Nashville

domain: entertainment


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From The Art and Popular Culture Encyclopedia
Kamera and Pamela Green
He founded the Kamera group of magazines with his then 'supposed' wife, the model and actress Pamela Green. They were never married, which put her at a disadvantge when they split, financially and regarding copyright and possession of photos, even of herself. Marks was also the photographic consultant for the film Peeping Tom, which also featured Green in a cameo role.
Besides Pamela Green, his most popular models were probably June Palmer, Paula Page and Vicky Kennedy, who under her birth name of Margaret Nolan, went on to be an actress, in Carry On, Bond and other films, in the theatre and on TV, notably in Steptoe and Son.
In 1958, as an offshoot of his magazines, Marks began making short films for the 8mm market of his models undressing and posing topless, popularly known as “glamour home movies”. A recent episode of BBC’s Balderdash and Piffle programme attributed the earliest use of the word “glamour” as a euphemism for nude photography to Marks’ 1958 publicity materials. One of Marks’ most popular 8mm glamour films was The Window Dresser (1961), starring Pamela Green as a catburglar who hides from the law by posing as a lingerie shop dummy. Marks does a character turn as the shop’s exaggeratedly gay owner, but the short’s obvious raison d’etre remained Pam’s show stopping shop window striptease. After a judge threw out an obscenity charge against The Window Dresser (according to legend remarking “I’ll buy a copy for my son, case dismissed”), Marks continued to make more 8mm glamour films throughout the 1960s. Marks’ background as a music hall performer is evident in the “silly little stories” he would devise for his 8mm glamour films, as well as the occasional bit parts he would write for himself and his onetime comedy partner Stuart Samuels (a.k.a. Sam Stuart).
Marks feature films as a director were Naked as Nature Intended (1961), The Chimney Sweeps (his only non-sex film, 1963), The Naked World of Harrison Marks (1965), Pattern of Evil (1967), The Nine Ages of Nakedness (1969) and Come Play With Me (1977). Pattern of Evil a.k.a. Fornicon, a heavy S&M film with scenes of murder and Monique Devereaux whipping Marks regular Howard “Vanderhorn” Nelson in a torture chamber, was never shown in the UK. Marks implied in several interviews over the years that the film was financed by the criminal element.
After directing The Nine Ages of Nakedness, Marks endured a partially turbulent time in the early seventies when he was made bankrupt (in 1970), was the subject of an obscenity trial at the Old Bailey (in 1971) and his drinking began to become more heavy. Marks made ends meet during this period by continuing to shoot short films for the 8mm market and releasing them via his Maximus Films company
Based out of Marks’ Farringdon studio, Maximus was run on a ‘film club’ basis, meaning that punters would have to sign up for membership before purchasing the films, mirroring the way membership only sex cinemas were run at the time. While his earlier 8mm films largely consisted of nothing more explicit than the models posing topless, late sixties titles like Apartment 69 and The Amorous Masseuse were generally soft core sex affairs, that also provided some notable discoveries. Sue Bond, later in sitcoms and The Benny Hill Show, began her career in Marks soft core sex shorts of this period. Pat Astley, some years before playing 'Young Mr Grace's Nurse' in Are You Being Served?, had appeared in the Marks short Doctor Sex. While the Collinson Twins (Mary Collinson and Madeleine Collinson) had also appeared in several Maximus shorts, including “Halfway Inn”, prior to starring in Hammer’s Twins of Evil.
Marks had also began making hardcore shorts for a man known only as “Charlie Brown”, and occasionally made hardcore versions of his Maximus short films which were released overseas on the Color Climax label. “Unaccustomed as I Am”, a black and white Maximus short, for instance, was also filmed in a colour hardcore version called Die Lollos (a.k.a The Customs). In later years Marks was reluctant to discuss these hardcore short films and claimed ‘not to remember’ their titles, some however have resurfaced including Dolly Mixture (1973) - a horror film spoof starring his 1970s discovery Clyda Rosen- , Autograph Hunter, Duty Free, Bistro Bordello starring Ava Cadell and Busty Baller (1979). The latter, in which big bust model Nicky Stanton seduces a passing Window Cleaner, was also filmed in a softcore version called Busty Ravers.
In the wake of the success of his early "glamour" films GHM also produced a series of slapstick comedies also sold via the photographic shops and magazines that were the outlet for his adult work. As well as directing these films he also appeared as one of the main actors. These were founded in the music hall and classic silent comedy traditions. Needless to say they were less successful than his girlie films and the competition from the real thing i.e. the Chaplin Keaton Lloyd classics that he paid homage to and which provided most of the package film releases of the day. In the late 1970’s Marks was hired as photographer for Janus magazine- which specialized in spanking material- even managing to get his bodybuilder friend Howard Nelson on the front cover of issue two (as a “spanking milkman”). Marks also began making short films for the magazine on 8mm. Late for School made in 1977 would appear to be one of the earliest, these shorts featured actresses recognizable from soft core films of the period like Come Play With Me’s Lisa Taylor and Sonia Svenberger. In 1982 Marks left the Janus stable to set up his own magazine Kane on the same subject. Corporal punishment would now become Marks’ big theme for the final act of his career. Making the transition from 8mm to videotape, Marks made around 80 videos of this nature with titles like The Spanking Academy of Dr. Blunt and Stinging Tales still being turned out in the early 1990s. As with the 8mm striptease films and Naked As Nature Intended, the spanking videos clearly existed solely for the purpose of titillation yet at the same time adopted an asexual stance, bringing Marks career curiously full circle.
The British Russ Meyer
Marks was in many ways the British equivalent of Russ Meyer. While Marks was never the filmmaker that Meyer was, both made their names as photographers, both had an obsession for large breasted women ("big tits sell" was a Marks maxim), and both would eventually become a byword for a certain form of erotica that has since passed into history.


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Written and directed by Conor McPherson with music and lyrics by Bob Dylan, performances will begin at London's Gielgud Theatre December 10 and continue through February 1, 2020. The London engagement will follow a run at Toronto's Royal Alexandra Theatre that opens September 28.
The full London cast includes Daniel Bailey
(Ensemble), Colin Bates (Gene Laine), Katie Brayben (Elizabeth Laine), Anna Jane Casey (Mrs. Burke),
Nicholle Cherrie (Ensemble), David Ganly (Mr. Burke), Simon Gordon (Ensemble), Steffan Harri
(Elias Burke), David Haydn (Ensemble), Rachel John (Mrs. Neilsen), Sidney Kean (Mr. Perry), Finbar
Lynch (Reverend Marlowe), Donald Sage Mackay (Nick Laine), Gloria Obianyo (Marianne), Ferdy
Roberts (Dr Walker), Wendy Somerville (Ensemble), Gemma Sutton (Katherine Draper), Shaq Taylor
(Joe Scott), and Alan Vicary (Ensemble).
Set in 1934, the show offers a slice-of-life look at a small community in Duluth, Minnesota, where the Laine family operates a rundown guesthouse.
Girl From the North Country opened at The Old Vic in July 2017 and subsequently transferred to the Noël Coward Theatre in December 2017, winning 2018 Olivier Awards for Best Actress in a Musical and Best Supporting Actress in a Musical. It made its U.S. debut at Off-Broadway’s Public Theater last year.
Girl From the North Country features scenic and costume design by Rae Smith; orchestrations,
arrangements, and music supervision by Simon Hale, with additional arrangements by
Hale and McPherson; lighting design by Mark Henderson; sound design by Simon
Baker; movement direction by Lucy Hind; and casting by Jessica Ronane CDG.
Girl From the North Country is produced by Tristan Baker & Charlie Parsons for Runaway Entertainment, Steven Lappin, Sony Music Entertainment UK, David Mirvish, and The Old Vic.

domain: artistic


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Moonlight Movies in Greenville
September 18 @ 6:30 pm - 9:00 pm
An event every week that begins at 6:30 pm on Wednesday, repeating until September 26, 2019
Come early to grab a good seat and play trivia with us before the show. Movies begin at sundown in Falls Park every Wednesday in May & September. A local food truck and Poppington’s Popcorn will be on-site.
Feel free to bring your own picnic and enjoy a cozy night under the stars!
$1 wristbands must be purchased on-site if you plan on bringing alcohol.


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Below are FAQs and topics related to invoices, payment history, and account credits available to you on MerckVaccines.com:
Merck Account Open
These are the invoices you billed to your Merck Account.
Credit Card Scheduled
These are invoices scheduled-to-be-billed to your credit card.
These are the invoices that have been paid in partial or full. Partially paid invoices also appear on the “Merck Account – Open” tab and can be paid from there.
Payment history provides a list of all payments made.
Account credits can be applied when you pay an open invoice (on the “Merck Account – Open” tab) or pre-pay a scheduled payment (on the “Credit Card – Scheduled” tab).
This tab allows you to download reports in Excel of any of the Payment tabs. Reports are generated in .csv format to easily import into spreadsheet programs.
What forms of payment does MerckVaccines.com accept?
When you order online on MerckVaccines.com you have two choices:
- You can use a credit card or be invoiced for an order. Invoices must be paid with a credit card.
- A personal/business check, if you wish to mail in your payment. Send your payment, along with the remittance stub (bottom of invoice), to the address listed on the stub.
How long does it take for payment to post to my account?
Once Merck receives payment, it may take up to 1 business day for a payment to post to your account and for your invoice to be listed as paid.
How do I use a credit to pay for an invoice?
Go to Ordering then Payments and find the invoice you want to pay. First specify the amount to pay on the invoice, click the green “Make Payment” button, and you will be prompted to apply any credits on your account.
View your credits available by clicking the “Account Credits” tab under Payments.
Searching for Paid Invoices
Search paid invoices by invoice number on the All Paid page in the Payments area (within Ordering). You can also find a paid item by status and payment date.
Note that you can also view your pending and scheduled payments as well as payment history and available credits.
Searching for Payment Information
You can search your payment history by payment number on the Payment History page in the Payments section. You can also find payments by status and payment date. Pending means that the payment hasn’t posted to your account yet and it may take up to 1 business day for a payment to post.

domain: finance


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Today I'm lobbying with a 150 teen sex trafficking survivors & advocates for the passage of the Trafficking Victims Protection and Justice Act.
It's an incredible honor to stand beside these brave, resilient survivors and advocate for this law.
Here's why passing the #TVPJA is vital for survivors of sexual exploitation (ie #trafficking):
We are asking lawmakers to pass the #TVPJA bill which would prosecute traffickers as a violent crime with higher penalties.
Why? Well because, right now traffickers are prosecuted as a NON-violent crime and receive more leniency than criminals sentenced just for child abuse.
What does that mean? Say for example you rape a kid and are caught, right now in NYS, you'll get a tougher punishment than a trafficker.
BUT if you rape a kid, then pay him or her $20, beat the crap out of them (maybe even murder them), force them to have sex with multiple strangers and take away all their rights, freedom and dreams, THEN, IF you are caught, and IF you are sentenced you will receive a LESSER penalty than if you "just" committed child sex abuse. INSANE.
You can help! Take action here: www.eqaulitynow.org/take_action/TVPJA
Then message your senator and assembly person to urge them to pass the full #TVPJA. (More info on that here: www.tvpja.com) And if you're not in NY, message your state's assembly members and senators to do the same!
As one of the teen sex trafficking survivors said today, "We are fighting for the #TVPJA bill to be enacted so that victims receive the freedom they deserve and pimps and johns get theirs."
Amen, sister. Amen.

domain: politics


text:
Leading US economist advises Taoiseach to repeat demands for debt relief
Ken Rogoff says it is not in Europe’s interest for Ireland to grow slowly
Shinzo Abe, Japan’s prime minister (left) and Hassan Rouhani, Iran’s president, on the opening day of the World Economic Forum. Photograph: Jason Alden/Bloomberg
Mr Kenny, accompanied by Minister for Finance Michael Noonan, will meet business and political leaders and attend an IDA investor dinner this evening.
Ahead of the Taoiseach’s appearance this evening on a panel discussing European competitiveness, Prof Rogoff said it was “not in Europe’s interest for Ireland to grow slowly”.
“Of course Mr Kenny has to accentuate the positive and talk people into investing in Ireland but he also has to say, ‘We have tough decisions ahead’,” Prof Rogoff told The Irish Times.
“If there is talk of debt writedowns for Portugal, Ireland has to say, ‘We tried hard, we adjusted, what about us?’
“A debt write-down for Ireland would be the right thing for Europe to do.”
After dominating Davos for three years, the euro crisis is moving down the agenda. An early panel yesterday framed the discussion in a hopeful tone, asking “Is Europe Back?”
That didn’t prevent ex-Bundesbank president Axel Weber warning that, although Europe had stabilised, it faced low growth and renewed instability this year.
One source of concern was the potential rise of more extremist parties in May’s European election, he said. Another potential source of instability, he said, could come with investors trying to bet on the winners and losers of looming European bank stress tests.
“An exam where everyone passes is usually viewed as not being a credible exam,” said Prof Weber, who is chairman of Swiss bank UBS, which is not part of the stress tests. “And I expect some of the banks not to pass this test. Despite the pressure from politics, some will not pass.”
Fellow panellist Martin Sorrell of WPP, the world’s largest advertising firm, said he was “very bullish” about growth prospects for “the bookends of Europe”: the UK, Germany and Poland. France, Spain and Italy, meanwhile, remained at various downward stages of economic downturn.
A Davos survey from consulting group PwC indicated that about twice as many chief executives are confident about the coming 12 months than last year, with the world’s most confident managers based in western Europe.
Some 44 per cent of executives said they saw an improvement in the global economy. Just 7 per cent see a global decline on the cards this year, down from almost a third.
Technological concerns are looming large this year at Davos, led by ongoing revelations about surveillance by US intelligence on global communications.
Yahoo chief executive Marissa Mayer told delegates she expected the White House to provide greater transparency on the data collected by the NSA.
“We need to be able to rebuild trust with our users, not only in the US. but internationally,” she said. “People don’t know what data is being collected and how it is being used.”
Cisco Systems chief executive John Chambers called for global rules of the road on privacy, calling existing regime a “wild west”.
From the conference floor, internet pioneer Tim Berners- Lee warned that revelations of mass collection had yet to trigger a debate on the uses of the data collected.
“You have no idea if these people are American citizens or if they have been suspected of committing some sort of crime,” he said.
Today’s proceedings in Davos are likely to be dominated by Iranian president Hassan Rouhani, the first appearance by an Iranian leader in Davos in a decade.
Amid continued resistance on Iran joining Syrian talks in the Swiss town of Montreux, speculation is growing that Mr Rouhani will meet US secretary of state John Kerry on the Davos fringes.
Meanwhile in an aviation, if not diplomatic, coup Swiss authorities succeeded yesterday in bringing Iran together with its old regional enemy, Israel by making them park their respective jets beside each other on the tarmac of Zurich airport.


text:
US 5499460 A
A thermal barrier in the form of a base material with a plurality of microcapsules containing a phase change material forms an insulative pad, such as a shoe insole. The microcapsules are surroundingly encapsulated and embedded within the base material. In addition, substantially all of the microcapsules are spaced apart from each other, the space between neighboring adjacent microcapsules containing a phase change material. The microcapsules may be anisotropically distributed to further reduce thermal conductivity of heat through the thermal barrier.
1. An insole having thermal energy storage and insulative properties adapted to be positioned within an article of footwear to protect the foot and comprising:
a flexible resilient base material forming an insulative pad,
a plurality of microcapsules integral with and dispersed throughout at least a longitudinal section of said pad, and wherein said microcapsules are individually surroundingly encapsulated and embedded within said base material, and further wherein substantially all of said microcapsules are spaced apart from each other, the space between neighboring adjacent microcapsules comprising base material, said microcapsules containing a temperature stabilizing means;
whereby the insole exhibits enhanced thermal stability and thermal insulation properties.
2. The insole according to claim 1 wherein said microcapsules are leak resistant, whereby the insole may be subjected to the repeated external stresses of ambulation with minimum changes in the thermal capacitance and insulation properties of the insole.
3. An insole according to claim 1 wherein said temperature stabilizing means comprises a phase change material.
4. An insole according to claim 1 wherein said temperature stabilizing means comprises a material selected from the group of paraffinic hydrocarbons consisting of n-Octacosane, n-Heptacosane, n-Hexacosane, n-Pentacosane, n-Tetracosane, n-Tricosane, n-Docosane, n-Heneicosane, n-Eicosane, n-Nonadecane, n-Octadecane, n-Heptadecane, n-Hexadecane, n-Pentadecane, n-Tetradecane, and n-Tridecane.
5. An insole according to claim 1 wherein said microcapsules range in diameter from about 1.0 micron to about 1000 microns.
6. An insole according to claim 1 wherein a portion of said microcapsules contain a first temperature stabilizing means for maintaining the warmth of the foot and others of said microcapsules contain a second temperature stabilizing means for cooling of the foot.
7. An insole according to claim 5 wherein said microcapsules are anisotropically distributed within said insole.
8. An insole according to claim 7 with enhanced thermal storage properties wherein said anisotropic distribution concentrates said microcapsules in the upper portion of said insole and in a plane substantially parallel to the underside of the plantar portion of the foot and further wherein said insole may be thermally recharged for re-use.
9. An insole according to claim 1 wherein said base material is a polymer.
10. An insole according to claim 9 wherein said polymer is a moldable foam.
11. An insole according to claim 10 wherein said foam is open-cell.
12. An insole according to claim 10 wherein said foam is closed-cell.
13. A method of protecting the foot from the deleterious effects of prolonged exposure to cold and comprising the steps of:
(a) thermally charging a flexible resilient insole of the type having a base material forming an insulative pad and a plurality of microcapsules containing a phase change material dispersed throughout at least a longitudinal section of the pad, and wherein the microcapsules are individually surroundingly encapsulated and embedded within the base material, and further wherein substantially all of said microcapsules are spaced apart from each other, the space between neighboring adjacent microcapsules comprising base material, to a temperature where the phase change material melts;
(b) inserting the thermally charged insole into an article of footwear immediately prior to use,
whereby the insole forms an additional barrier between the foot and the external environment.
14. The method according to claim 13 wherein the microcapsules are anisotropically distributed so that they are concentrated in the upper portion of the insole in a plane substantially parallel to the plantar portion of the foot.
This application is a continuation-in-part of U.S. patent application Ser. No. 08/129,490 filed Sep. 30, 1993, now abandoned, which is a continuation application of U.S. patent application Ser. No. 07/837,762 filed Feb. 18, 1992, now abandoned.
This invention relates generally to the field of foamed insulation materials and more particularly to insulation materials for use in clothing, for example, shoe soles/insoles.
The rate of a person's thermal exchange with the environment is dependent upon a number of factors, such as activity level, the nature and condition of the environment, and the characteristics of the clothing having contact with the wearer's skin. The transfer of body heat from the skin through clothing or footwear to the environment takes place by conduction, convection, radiation and evaporation, the physiological details and mechanisms of which are generally well known.
In footwear, conduction or convection from the foot through the shoe to the environment is the main mode of heat loss from the foot to the outer surface of a shoe or boot. Thermal energy is principally transferred by conduction through the footwear, and is thereafter transferred by conduction or convection as well as radiation from the sole to the environment.
Given the propensity for the extremities and particularly the feet to easily become cold, it is logical for efforts to have been made to improve the insulating capacity of shoe soles and/or insoles. U.S. Pat. No. 4,658,515 to Oatman entitled "Heat Insulating Insert For Footwear" discloses a heat retention insole for shoes comprising a laminated structure incorporating a flexible plastic bottom sheet, a similar plastic upper sheet, a space sheet formed primarily of a foamed organic plastic material. The spacer sheet includes large area apertures defined by bars extending transversely between portions of a parametrial band portion. These large area apertures are loosely filled with particles of insulating plastic materials (such as hollow polystyrene or polyethylene beads) which also serve to maintain the top and bottom sheets in a spaced relationship even when subjected to foot pressure. The outer surfaces of the insole are preferably provided with a heat reflecting coating or film to minimize the loss of heat from the foot by radiation and reflect any such radiated heat back in to the foot of the wearer. While somewhat effective, this insole relies on trapped air within cellular spaces to retard the flow of heat. Compression of the insulating material reduces the volume of the trapped air space which, in turn, increases thermal conductivity and increases the rate of heat loss through the footwear.
Another example of an insulating insole is disclosed in U.S. Pat. No. 4,055,699 to Hsiung which teaches a multi- layer insole that is adapted for insertion into an article of footwear to insulate the foot from the cold developed in the sole and sock lining, from walking on a cold surface, the insole being thin enough to fit within the footwear without requiring an increase in footwear size. The insole comprises four layers, including from top to bottom, a top layer of soft fabric for comfortable contact with the plantar surface of the foot or sock of the wearer, a second layer of thermoplastic foam cushioning material, a third layer which is more effective than the remaining layers in insulating the foot against cold, and a fourth layer that is an aluminized polymeric material of paper thinness. Again, compression reduces efficacy.
Still another attempt at maintaining the warmth of the foot is found in U.S. Pat. No. 4,331,731 to Seike et al. which discloses an exothermic body for use as a shoe insole. The insole includes a foamed plastic sheet having cells therein and an exothermic agent such as a mixture of iron, saline solution, activated carbon and woodmeal or pulp powder. The foamed sheet is covered by an air-permeable, thin film such as a thick perforated plastic film. A cushion material is provided on at least one surface of the foamed plastic sheet covered with the air-permeable thin film and the foamed plastic sheet together with the cushion material covered by an air permeable film cover. This device is not rechargeable and is, therefore, an expensive and temporary solution to the problem.
It is, therefore, an object of the present invention to provide a shoe insole having enhanced ability to insulate the foot from hot or cold.
Another object of the present invention is to provide a shoe insole that is compatible with existing footwear and which may be used without the necessity of the user purchasing footwear larger than that normally worn.
Yet another object of the present invention is to provide a shoe insole with enhanced insulating properties that also has a high degree of structural integrity.
A still further object of the present invention is to provide a shoe insole having enhanced thermal storage properties that is reusable.
A related object of the present invention is to provide a shoe insole with limited compressibility and which, therefore, enhances thermal management of the foot.
In accordance with the present invention, there is provided, an insole adapted to be removably positioned within an article of footwear to insulate the foot from heat or cold and provide auxiliary heat from stored energy. The insole comprises a flexible resilient base material forming a pad. A plurality of microcapsules are integral with and dispersed throughout at least a portion of the base material and contain a temperature stabilizing means, such as a phase change material, for example, paraffinic hydrocarbons. The microcapsules are individually surroundingly encapsulated and embedded within the base material. Substantially all of the microcapsules are spaced apart from each other and the space between neighboring adjacent microcapsules is base material. Furthermore, the insole may include an anisotropic distribution of particles such that they are concentrated closer to the plantar region of the foot. Alternatively, the insole may be multilayered, with the upper layer containing microcapsules and the lower layer a microcapsule free insulator.
Some of the objects of the invention having been stated, other objects will appear as the description proceeds when taken in connection with the accompanying drawings in which
FIG. 1 is a cross section of a microcapsule according to the present invention containing a phase change material.
FIG. 2 is a perspective view of an insole according to the present invention.
FIG. 3 is a sectional view of an insole according to the present invention taken along line 3--3 of FIG. 2 wherein microcapsules are embedded within a foam.
FIG. 4 is a sectional view taken along line 3--3 of FIG. 2 of a second embodiment of the insole according to the present invention wherein microcapsules are anisotropically embedded within a foam comprised of two layers.
FIG. 5 is a sectional view taken along line 3--3 of FIG. 2 of a third embodiment of the insole according to the present invention wherein microcapsules are anisotripically embedded within a single layer foam.
While the present invention will be described more fully hereinafter, it is to be understood at the outset that persons of skill in the art may modify the invention herein described while still achieving the favorable results of this invention. Accordingly, the description which follows is to be understood as being a broad teaching disclosure directed to persons of skill in the appropriate arts, and not as limiting upon the present invention.
The insole generally indicated at 10 is adapted to be removably positioned within an article of footwear (not shown) to insulate the foot from heat or cold and comprises a flexible resilient base material forming a pad. A plurality of leak resistant microcapsules 20 (indicated by the dark dots in FIGS. 3 & 4) are integral and dispersed throughout the base material. The microcapsules 20 are individually surroundingly encapsulated and embedded within the base material. In addition, substantially all of the microcapsules 20 are spaced apart from each other, the space between neighboring adjacent microcapsules being base material. The microcapsules contain a temperature stabilizing means 30.
The base material forming the pad is a polymeric material such as a moldable foamed organic plastic 40. The air cells 42 are schematically illustrated in FIGS. 3 & 4 as the circular white dots. Exemplary of acceptable polymers employed in the footwear industry are polyurethane, ethylene/vinyl acetate (EVA) copolymer, latex, polyethylene, polypropylene, butyl, silicone, cellulose acetate, neoprene, epoxy, polystyrene, phenolic, and polyvinyl chloride (PVC). The foregoing may be foamed or not, depending on the particular material selected. The foam may also be closed cell or open cell, again depending on the particular application.
The microcapsules 20 can range in size from about 1.0 to about 1000.0 microns and are formed according to conventional methods well known to those skilled in the art.
The microcapsules contain a temperature stabilizing means or phase change material 30 such as eicosane. Additionally, plastic crystals such as 2,2-dimethyl-1,3-propanediol (DMP) and 2-hydroxymethyl-2-methyl-1,3-propanediol (HMP) and the like may be used as the temperature stabilizing means. When plastic crystals absorb thermal energy, the molecular structure is temporarily modified without changing the phase of the material. For high temperature applications low melting point eutectic metals such as low melting point solders may be employed.
In another aspect of the invention, the composition of the properties for a given temperature range. For example, the melting point of a homologous series of paraffinic hydrocarbons is directly related to the number of carbon atoms as shown in the following table:
______________________________________Compound Number of Melting PointName Carbon Atoms Degrees Centigrade______________________________________n-Octacosane 28 61.4n-Heptacosane 27 59.0n-Hexacosane 26 56.4n-Pentacosane 25 53.7n-Tetracosane 24 50.9n-Tricosane 23 47.6n-Docosane 22 44.4n-Heneicosane 21 40.5n-Eicosane 20 36.8n-Nonadecane 19 32.1n-Octadecane 18 28.2n-Heptadecane 17 22.0n-Hexadecane 16 18.2n-Pentadecane 15 10.0n-Tetradecane 14 5.9n-Tridecane 13 -5.5______________________________________
Each of the above materials can be separately encapsulated and is most effective near the melting point indicated. It will be seen from the foregoing that the effective temperature range of the insole can, therefore, be tailored to a specific environment by selecting the phase change materials required for the corresponding temperature and adding microcapsules containing the material to the insole.
In addition, the insole 10 can be designed to have enhanced thermal characteristics over a wide range of temperature or at discrete temperature ranges through proper selection of phase change material.
In fabricating the insole 10, the desired encapsulated phase change materials are added to the base polymer (liquid or solution) and fabrication is accomplished according to conventional methods which may include foaming. Typical concentrations of microencapsulated phase change particles added to the base polymer material range from about 20% to about 60% by weight. The foregoing concentrations are believed to allow the insole to be subjected to the repeated mechanical stresses of ambulation with minimum changes in the thermal characteristics of the insole. During fabrication, a base material is formed by selecting a liquid polymer and/or elastomer and then causing the foregoing to be foamed. Common methods of foaming include adding a hardening agent which causes a chemical reaction, thermally setting the base material with heat, or bubbling a gas through the liquid polymer/elastomer while hardening, or other methods well known to those skilled in the art. The microcapsules would be added to the liquid polymer/elastomer prior to hardening and mixed therein to ensure wetting and equal dispersion throughout the mixture. After mixing, the microcapsules will be wetted and substantially all will be spaced apart from each other. Thus, when the base material is foamed by the methods described above, the microcapsules will be embedded within a base material matrix so that they are individually surroundingly encapsulated and embedded within the base material and further, the space between neighboring adjacent microcapsules will be base material and not the foaming gas. It is believed that the wetting step coats the microcapsules and that the surface tension of the polymer/elastomer maintains the coating around the microcapsules during and after foaming. In addition, the surface tension of the foamed bubble prevents the PCM particles from crossing the boundary into the bubble. Thus, the gas pockets formed during foaming are substantially free of microcapsules.
It will be noted that the microcapsules embedded within a foam as described above are actually surrounded by two distinct walls. The first being the microcapsule wall itself and the second being the wall formed by the foam. Thus, the propensity for the phase change material to leak out of the insole is substantially reduced. The net result is repeatability of thermal response when the insole is re-used.
In the fabrication of the invention, the microcapsules 20 need not be evenly distributed throughout the entire insole. For example, the microcapsules 20 may be anisotropically distributed so as to concentrate them in the upper portion of the insole in a plane substantially parallel to the underside of the plantar region of the foot. It is believed that the loading or concentration of the particles in the insole would decrease from an initially selected concentration (top being nearest the foot) by one- half as one moves by quartiles away from the top as follows:
______________________________________First quarter of insole 100% (top)Second quarter of insole 50%Third quarter of insole 25%Fourth quarter of insole 0% (bottom)______________________________________
Similarly, the insole may be fabricated in two or more layers 40a,40b as shown in FIG. 4, only one of which contains microcapsules. These layers- are then bonded together using conventional methods with the net result being a concentration of microcapsules 20 proximate the foot embedded in the base material. The various layers 40a,40b may be of the same or different materials, depending on the particular application. Alternatively, both layers may contain microcapsules to form an additional thermal barrier.
It will be appreciated that the insole according to the invention will have enhanced value if produced to have application in heat as well as cold. For example, the insole 10 could be inserted into footwear which would be cold during winter and hot during summer. Furthermore, a single phase change material can be employed to both heat and cool a shoe. For example, an insole having a PCM selected to melt at higher temperatures can be thermally charged simply by being present in a room proximate a heat source. Thereafter, when in use in a cold environment such as ice or snow, the foot of the user will remain warm for an extended period of time and will protect the foot of the wearer for a substantial period of time beyond that of standard non-PCM containing footwear until the phase change material solidifies. Similarly, in summer, when the same insole is stored in a relatively cool environment, such as within a home or office and is then used, for example, on a hot asphalt roadway, the foot will remain cool until the phase change material melts. A preferred method would be to pre-cool the insole in a conventional refrigerator. Additionally, the insole could be fabricated with microcapsules containing two discrete types of phase change material, one suitable for assisting maintaining the foot of the wearer at each of two desired temperatures.
The insole may be used as a thermal storage device, somewhat similar to a battery. In operation, the user may preheat (or precool) the insole prior to insertion within the article of footwear. Alternatively, the preheating or pre-cooling as the case may be, may be accomplished simply by returning inside after having been out of doors (for example, in the snow when the microcapsules will be recharged from the warmer air present inside, i.e., near a fireplace or other heat source, or recharged for re-use by metabolic heat production during high activity levels).
While the foregoing description makes reference to a shoe insole, the reader will note that the present invention has wide application not only in other areas of the shoe but in many related items of clothing or padding. The present invention contemplates fabrication of the shoe sole from a foam pad produced according to conventional means. Therefore, one method of producing the insoles is in the form of a large flat sheet. The sheet then passes through a punch press which cuts out individual insoles. The reader will note that the sheet may be used as linings in gloves, hats, outerwear, and underwear and the present invention may, therefore, be regarded generally as a thermal barrier.
In addition to the uses specified above, the reader will appreciate that the thermal barrier could have additional uses in its sheet form. For example, certain products such as pharmaceuticals must be maintained at or below maximum temperatures. This is often a difficult undertaking when transportation is required. Therefore, the present invention will find application as a thermal "blanket". The blanket is charged by freezing the phase change materials within the microcapsules and may then be wrapped around the product to maintain the temperature thereof.
The foregoing embodiments and examples are to be considered illustrative, rather than restrictive of the invention, and those modifications which come within the meaning and range of equivalence of the claims are to be included therein.

domain: chemistry


text:
Wednesday, March 28, 2007
More Little Hands
More little hand came to pet the puppies. Lena, Nicole and their Grandma Patti came to just pet, cuddle and love. The puppies just love little people, they climb on them and they can see their faces and they look into their eyes. We have to really get down to get that close to them. Then when they are done they just crash and sleep anywhere.

domain: pet


Posted Dec 11, 2012By
Protesters rally outside the state Capitol as lawmakers push final versions of right-to-work legislation in Lansing, Mich., Tuesday, Dec. 11, 2012. The GOP majority has used its superior numbers and backing from Gov. Rick Snyder to speed the legislation through the House and Senate last week, brushing aside denunciations and walkouts by helpless Democrats and cries of outrage from union activists who swarmed the state Capitol hallways and grounds.
Students attend the homecoming dance at Central York High School on October 18, 2014. Also of interest: Aerial view
The York Arts staff invites anyone to explore their mind’s eye by submitting poetry or short stories for the
Take a look inside the interior the Montgomery Ward building at 34 Frederick Street, which is planned to become a d
Portraits of new U.S. citizens sworn in at a naturalization ceremony held at York County Administration Center on T
Teachers, clergy, residents and others opposed to a proposed alternative plan that would convert some York City Sch
Students attend the homecoming dance at William Penn High School on Saturday, Oct. 11, 2014.


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The following article highlights the work of Dr. Nancy Klimas, MD, an international leader in ME/CFS research, and features her succinct explanation of the basic mechanisms involved in ME/CFS. It is reproduced with kind permission from the Spring 2007 issue of University of Miami Medicine, the magazine of the Leonard M. Miller Schol of Medicine at the University of Miami (FL), where Dr. Klimas is Professor of Medicine, Psychology, Microbiology, and Immunology, and Director of the Allergy and Immunology Clinic.
Sick and Tired
By Jeanne Antol Krull
After 20 years of research, the cause of Chronic Fatigue Syndrome is still elusive – but physicians and scientists at the Miller School of Medicine are at the forefront of efforts to understand and develop effective treatments for the debilitating disease.
In 1984 a woman suffering from severe fatigue, body aches, and difficulty concentrating walked into the office of clinical immunologist Nancy Klimas, MD, with a medical file several inches thick – the result of visits to more than a dozen doctors. One piece of treatment advice she was given: “Change your hair color and get a manicure. You’ll feel better.”
But the patient knew better, telling Klimas simply, “I think there’s something wrong with my immune system.”
Those words would dramatically change the course of Klimas’s academic medical career and land her and her collaborators at the Miller School of Medicine at the forefront of understanding and trying to find a treatment for a baffling and debilitating disease that would come to be known as chronic fatigue syndrome.
If there was something wrong with your immune system, Klimas was the one to see in South Florida, and at the time her practice was mainly HIV patients. Klimas sent the patient’s blood sample to colleague Mary Ann Fletcher, Ph.D., professor of medicine, microbiology/immunology, and psychology, and asked her to “look at this any way you know how.” Fletcher’s lab was already doing groundbreaking work on the role of the body’s natural killer cells, which kill tumor cells or any pathogens in the blood.
“Mary Ann reports back, ‘There is something very odd about her blood work. She has less natural killer cell function than we see in end-stage AIDS patients, and her immune activation markers are very high,’” Klimas recalls. “I called the patient and told her, ‘I can’t tell you what’s wrong, but your labs are very abnormal.’ She burst into tears, she was so happy to hear something was wrong with her.”
It would be four more years before the Centers for Disease Control and Prevention (CDC) would formally define chronic fatigue syndrome, and the original definition would change over time as scientific knowledge evolved. Before then the disease was known as chronic Epstein-Barr virus syndrome, but that name was eliminated as other viruses and etiologies came into play.
The disease is characterized by profound fatigue that is not improved by bed rest and may be worsened by physical or even mental activity. No matter what the name or how debilitating the symptoms, those who suffered from it—mainly women—were called everything from hypochondriacs to just plain crackpots.
After a 17-year nursing career, Bonnie Mayer, then 45 years old, was fulfilling a lifelong dream of getting a degree in fine arts at Florida International University. She went to bed on April 6, 1994, feeling well and happy and woke up the next day very ill. “The room was spinning wildly, I was extremely dizzy, sick to my stomach, I couldn’t walk, and I was very weak,” Mayer remembers. She was diagnosed with a virus, which had affected the inner ear or balance mechanism, but the worst was yet to come.
“A week later I was still sick, I had extreme fatigue, I couldn’t think, I couldn’t even get out of bed.” Over the next six months she would consult six different doctors before she received a chronic fatigue diagnosis.
“There are a lot of people who have this illness and don’t know it, and I was one of them,” Mayer says.
Patients like Mayer found some vindication late last year when the full weight of the federal government was brought to bear against the disease. At a news conference in Washington, the CDC kicked off the first-ever national public awareness campaign on the disease.
Invited to be one of only a handful of speakers was Klimas, who spent a six-month sabbatical doing research on chronic fatigue for the CDC. “I had been waiting for that day for a very long time,” says Klimas. “After treating more than 2,000 chronic fatigue syndrome patients over more than 20 years, I’ve seen patients who were angry and frustrated at trying to convince their physicians and loved ones that this is a real illness. They experience a level of disability equal to that of patients with late-stage AIDS and patients undergoing chemotherapy—and now finally they have a powerful voice on their side.”
The CDC estimates that 4 million Americans have chronic fatigue syndrome, and almost 80 percent of all cases are undiagnosed. Among those numbers are veterans with Gulf War illness who suffer symptoms identical to chronic fatigue.
The problem with making a diagnosis is that there is no laboratory test, and treatment is aimed only at symptom relief and improved function.
More than half the patients have sudden or acute onset, usually following a viral infection. “A recent prospective study found the one single predictor of who is going to stay sick after a viral infection is the severity of the initial viral infection,” says Klimas. “The other patients have a slow onset, they suffer for a year or two before they realize they just aren’t getting any better, and by that time they have many other complicating factors such as depression.”
When it comes to treating patients, Klimas says you don’t have to be a chronic fatigue expert — it comes down to basic clinical principles. Patients tend to have three main problems in addition to fatigue: sleep disruption, autonomic dysfunction (delayed drops in blood pressure after standing), and pain.
“As you take care of each of the pieces, one by one, your patient starts coming together and getting better and better,” says Klimas. “In particular, the patient takes a big step forward the day you get their sleep better. Sleep is a huge part of helping patients feel better right from the beginning.”
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Even though discovery of a cause is still elusive after more than two decades of searching, scientists have zeroed in on several key areas: infectious agents such as viruses, problems with hormone regulation in the body’s endocrine system, disturbances in the autonomic regulation of blood pressure and pulse, and immunologic dysfunction.
A multidisciplinary group led by Klimas at the Miller School of Medicine was among the first to recognize and report immune system abnormalities in chronic fatigue patients. As director of AIDS research at the Miami Veterans Affairs Medical Center, Klimas was already working with an existing team of UM and VA researchers on HIV, and she tapped into their expertise for this new battle.
“We were this big, diverse, multidisciplinary team in HIV, and I said, ‘Why can’t we do the same thing in chronic fatigue?’ Instead of looking at it myopically through one discipline, we’re the group that says, ‘These systems are all integrated to create what we call chronic fatigue syndrome,’” says Klimas.
"In looking at what generally happens to someone with this disease, it's easy to see how everything can go haywire. Think about when you get a virus: You feel pretty rotten, your immune system kicks in, everything quiets back down, and eventually you feel better. In chronic fatigue something revs up the immune system, but it never quiets back down.
For example, explains Klimas, “Whatever has stirred up your immune system in the first place can end up disturbing your sleep. When you don’t sleep properly, never going into stage three and stage four sleep, your body doesn’t release the nighttime hormones such as cortisol. A stress hormone, cortisol is a big part of why we quiet our immune system. It peaks in the morning when we wake up and resets the immune system for the day.”
When that doesn’t happen, the immune system that was activated yesterday gets even more activated today and the next day, and it starts releasing far too many cytokines, which are molecules that can make you ache all over and disrupt stage four sleep. These molecules can also cause adverse effects in the brain, leading to cognitive and memory problems.
“What you end up with is this vicious cycle of fairly subtle dysregulation between the body’s hormone system, the autonomic nervous system, and the immune system,” Klimas says. “Everything is just a little off kilter – and instead of helping each other, these systems together are amplifying the problem.”
Fletcher, the scientist who tested the very first patient’s blood, is the director of the E. M. Papper Clinical Immunology Laboratory at the Miller School and has done groundbreaking work since the early 1980s on the immune system and, in particular, on the role of natural killer cells in chronic fatigue.
“Initially it was quite difficult to get funding,” remembers Fletcher. “This was seen as a hysterical condition that middle-aged women might come down with.”
Fletcher recently received a new National Institutes of Health (NIH) grant to study the role of specific peptides—neuropeptide Y (NPY) and dipeptidyl-peptidase (CD26)—in the development of chronic fatigue. These molecules are important in the regulation of many physiological and disease processes in the immune, nervous, and endocrine systems. The study will examine the relationship between blood concentrations of NPY and CD26 and the severity of chronic fatigue symptoms. And that’s not all.
Fletcher and Klimas are now recruiting 150 patients for a five-year longitudinal NIH study that will assess patients at baseline, again on a day when they feel good, and on a day when they feel bad, even if they have to go to their homes to collect the blood.
“We’re going to be looking at a large menu of immunologic markers at each of these intervals and compare them to 90 healthy subjects,” says Fletcher. “We’re hoping to see which of the markers will be instructive and will they correspond to the symptoms. This should give us a much more complete picture of the disease, and hopefully we can set a menu both to facilitate the diagnosis of chronic fatigue syndrome and to measure the efficacy of new treatments.”
Problems with the autonomic nervous system, which controls cardiovascular, digestive, and respiratory functions (as well as the immune system), are common in patients with chronic fatigue. Many have difficulty with fainting spells and lightheadedness, especially shortly after standing. Researchers have found many of these same patients have low or below-normal red blood cell volumes.
Klimas and Barry Hurwitz, Ph.D., professor of psychology and medicine and part of the UM Behavioral Medicine Research Program at the VA Medical Center, headed a four-year NIH study that looked at whether the anemia drug Procrit could help these patients by increasing their red blood cell volume.
“Our preliminary findings show while the drug corrected their anemia, it did not decrease their fatigue,” says Hurwitz. “However, we did find there was a slight improvement in their ability to stay standing for a longer period of time without a drop in blood pressure. Every little piece we can add to the puzzle will help us discover the root cause or causes of this illness.”
An increase in stress plays a very significant role in managing chronic fatigue symptoms. “On a good day I am easily fatigued—I can get out of breath scrambling an egg,” says Bonnie Mayer. “But if I have a particularly long, stressful day, it is much harder to function for the next couple of days.
“For me life is an adaptation, and thanks to a great deal of family support, my life is certainly better now than it was at the beginning of this journey.”
For more than 20 years faculty in the Behavioral Medicine Research Program have been studying stress management among patients who have diseases that affect the immune system. Much of their early work focused on HIV patients, but there was reason to believe that stress also played a big role among chronic fatigue patients.
A UM study conducted after Hurricane Andrew in 1992 found that chronic fatigue patients who lived in Miami-Dade County and went through the stress of the storm had a serious exacerbation of their symptoms, while patients in Broward County did not.
“We also found patients who were more optimistic and had more social support as they moved through the hurricane did better,” says Michael Antoni, Ph.D., professor of psychology and psychiatry and behavioral sciences. “We took these findings and designed a study to evaluate the effect of a ten-week cognitive behavioral stress management intervention group during which chronic fatigue patients were taught techniques to deal with stress. We found a very positive outcome on better stress and symptom management.”
Since many chronic fatigue patients often don’t feel well enough to attend regular therapy sessions, the NIH recently funded an extension of the study to see if the same effect can be achieved through a telephone-based cognitive behavioral stress management intervention . A similar program has already been found to be beneficial among dementia caregivers.
The next frontier is clearly studying genetic factors in chronic fatigue. Findings released earlier this year showed patients have a genetic make-up that affects the body’s ability to adapt to change. Taking that research a step further, Klimas has received VA funding to conduct a gene microarray analysis of chronic fatigue and Gulf War illness patients both before and after exercise.
“The knowledge is coming at us very quickly now. It is going to translate into effective therapies, and I am so excited to be a part of it,” says Klimas. “On a personal level, it is really important to ask yourself if you made a difference that affected a lot of people beyond your own patient base, and the answer is yes, I think I did. But there’s still a lot more to do.”


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The Holy Synod of Greece’s Orthodox Church has agreed to send a letter of protest to Archbishop Elpidophoros of America after he baptised the twin children of a same-sex couple in the Athens suburb of Glyfada last week.
The church hierarchy also agreed to send a letter of protest to the Ecumenical Patriarchate in Istanbul, under whose canonical jurisdiction the Greek Orthodox Church of America lies.
The bishops unanimously voted on this move following a written complaint from the Bishop of Glyfada, Antonios.
In the complaint, the Bishop claimed Archbishop Elpidophoros did not inform him that the parents of the children were a gay couple when he requested to conduct the baptism.
Evanggelos Bousis and Peter Dundas, both of Greek descent and prominent men in Hollywood’s fashion industry, became the first gay couple to hold a Greek Orthodox baptism for their children in Greece on Saturday, July 9.
The couple’s children, Alexios and Eleni, were baptised by Archbishop Elpidophoros at the Panagia Faneromeni Church.
The baptism has been the subject of controversy across the Orthodox world, with one bishop telling Kathimerini that it “sent a message that is completely opposite to the teachings of the Greek Orthodox Church.”

domain: sociology


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Choose Between Two Options
- C$49 for a two-hour guided horseback tour for one (C$83 value)
- C$98 for a two-hour guided horseback tour for two (C$166 value)
Participants mount horses to explore the scenic Banff wilderness. Tours depart at 10 a.m., 12 p.m., 2 p.m., and 4 p.m. daily, and may be scheduled through October 1, 2014, or until the last day of the season.
Discover Banff Tours
Majestic pine trees sway in front of a mountain backdrop. Paddles break the river current. The experienced wilderness guides with Discover Banff Tours grant visitors modern methods for exploring the pristine natural landscapes in Banff National Park and the Canadian Rocky Mountains. In the winter, they lead groups on ice walks across frozen waterfalls and grottoes, helm dogsled and horse-drawn sleigh rides on wooded trails, and ski down Mt. Norquay–home of the first ski resort in the Canadian Rockies. Later in the year, guides lead grizzly-bear-watching tours and evening wildlife safaris on warm summer nights, and take adventurers whitewater rafting down Bow and Kananaskis Rivers. Year-round, they showcase the park’s rugged landscape on bus tours, and views of Mt. Norquay and the surrounding terrain via one of the two new available climbing routes or the famed chairlift. Staffers limit outdoors excursions to small groups, giving visitors one-on-one instruction while quickly checking that none in their party are bears in disguise.

domain: geography


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Australian Guide FASD Clinical Workshop Facilitator Manual
Published in 2016, the Australian Guide to the diagnosis of FASD was developed to assist health professionals in the assessment, diagnosis, referral and management of FASD. It contains the Australian FASD diagnostic instrument and information about how to use the instrument. The instrument was developed to facilitate and standardise the diagnosis of FASD in Australia. The Australian Guide provides clinicians with diagnostic criteria for FASD, which were agreed following a review of existing guidelines and consultations with clinical experts.
In May 2018 the Australian Government Department of Health funded ‘The National dissemination of the Australian Guide to the diagnosis of FASD and eLearning modules’ project to increase awareness of the Guide and diagnostic process and to support training for relevant clinicians.
As part of this project a series of FASD clinical workshops were held across Australia. A ‘FASD Clinical Workshop Facilitator Manual’ based on these workshops was developed by a team of health professionals and parents and carers.
The Facilitator Manual includes the FASD Clinical Workshop Training Package, which is a comprehensive teaching tool that contains the information, resources and activities required to conduct the workshop. It is intended for use by workshop facilitators and presenters.
The Facilitator Manual is divided into two sections:
- Part 1: Workshop coordination and adminsitration
- Part 2: FASD Clinical workshop Training Package - workshop PowerPoint presentation slides and accompanying notes, and videos
The framework set out in the manual can be adapted for a range of different clinical settings over one or two days. The workshop slides provide the fundamental information pertaining to the assessment for FASD as outlined in the Australian Guide and should be used as the basis for the workshop.
How to access the Facilitator Manual
The FASD Research Australia Centre of Research Excellence (CRE) and development team are pleased to make these valuable materials available for use in training health professionals to undertake assessments and in the use the Australian Guide.
The materials may only be used for non-commercial education and training purposes. No part of the materials may be reproduced or used for any commercial purposes.
To access the materials please email us and you will be sent a Licence Agreement and form which must be completed, signed and returned via email. Once this is received you will be provided with access to all materials.
For health professionals unable to attend a face to face clinical workshop, this series of videos filmed at the Adelaide FASD clinical workshop offers you the opportunity to listen to the workshop presentations (min:sec):
- Introduction to the assessment and diagnosis of FASD (19:08)
- Assessing maternal alcohol use (15:20)
- Medical assessment (15:20)
- Assessing neurodevelopmental impairments (27:17)
- A parent's perspective (10.30)
An additional video on conducting a case study is available once you have accessed the Facilitator Manual.


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7 Jul 2021
Search teams find the wreckage of a passenger plane carrying 28 people that had disappeared in a remote Russian peninsula. Sources from the emergency ministry have said that the search for survivors would be paused due to loss of light as the evening drew in, but initial reports have suggested no survivors would be found.
8 Feb 2019
A body retrieved from the wreckage of a crashed plane in the English Channel has been formally identified as Cardiff City's Argentina-born soccer player Emiliano Sala, British police said in a statement on Thursday.


Hitachi ZW80-5B Compact Wheel Loaders
A powerful performer in a compact package, the Hitachi ZW80-5B Compact Wheel Loader carries a 1.2 yd³ bucket capacity and a 66 horsepower engine output. It offers impressive productivity without compromising on efficiency. With an operating weight of 12,600 pounds, it delivers a substantial 8,270 lbf breakout force. This compact loader is designed for reliability, durability, and versatility, featuring advanced technology, operator comfort, and safety, while maintaining a strong focus on environmental performance.


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Figtree – Pumpkins and Blossoms – FQ Bundle [PRE ORDER]
$250.00 inc GST
Pumpkins and Blossoms is Figtree’s latest autumn themed fabric collection.
With oranges and greens and some greys, this is Joanna’s idea of a magical pumpkin afternoon!
This Fat Quarter bundles has a FQ (18″ x 21″ or 45cm x 53cm) of each of the 38 prints in this line!
These will arrive in Australia around June 2021.
To view the PDF with all the fabrics for this collection click here
Please select ‘Bill me for shipping when it arrives’ as your shipping option when you check out and we will work out the exact amount of shipping (in consultation with you) when your pre-orders arrive and bill you separately then. I am happy to keep pre-orders for you until they have all arrived and ship once.
Out of stock

domain: hobby


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What does BeachGlow mean to you?
BeachGlow is a charity-based organization that relies heavily on volunteers. Each year we have a brand ambassador program made up of college students with the goal to promote BeachGlow both in person and online. This year we reached out to our ambassadors to hear what they had to say about their experience and how BeachGlow has impacted them. Here's what they had to say:
To me, BeachGlow is more than just a music festival, or even a charity event. It's a movement and a stepping stone in the fight for creativity. It makes me feel good to know that there are people out there who care enough about music education in schools to bring people together through that common love, allowing kids the opportunity to grow up with music the way I did. I'm just grateful that I was given the opportunity to contribute to the good that BeachGlow is doing.
- Diona Akens, Kutztown University
BeachGlow is the perfect representation of what it means to take a bad situation and turn it into something beautiful. It gives me hope and validation that it truly does take only one person to create something bigger than themselves for the benefit of the world around them. What a beautiful thing it is that people from all over the world can come together, in pure love and appreciation of music, and give back to change the world. No matter how small, we can all make a difference if we join together with one shared goal, while at the same time celebrating and enjoying something we're all passionate about. I guess that's the true power of music.
- Laura Hoban, West Chester University
To me, BeachGlow means endless opportunities. BeachGlow gives festival goers and music lovers an unforgettable show with fun, good vibes, positive energy, and heart-pounding, bass-dropping music. Whereas BeachGlow grants leisure opportunity for some, it also grants educational opportunity to underprivileged, school-aged children. BeachGlow allows people of all generations, whether they're benefitting from Little Kids Rock or not, to explore the world of music and make memories that will last a lifetime.
- Kelly Lynch, Gwynedd-Mercy University
I think BeachGlow is drastically different from other music festivals because by attending, you not only have an amazing time, but you also help out a great cause, Little Kids Rock. I love music, dancing, and the sun, and what better way to incorporate all three than at BeachGlow. The times I've attended, I've had the best time of my life.
- Ana Loayza, Rutgers University
BeachGlow is a community, bringing together a group of people who want to make a difference. It allows us to enjoy what we love while helping so many people.
- Ilana Multak, Penn State
BeachGlow is a one-of-a-kind festival. Through all the sweat and adrenaline, there's really a greater "Glow" that resonates from the energy of being in an area with thousands of others who harbor the same sensations you do. You feel on top of the world. But what originally drew me to BeachGlow was its ambition and message. When you get the opportunity to engage in an event where you feel good and can do good helping the lives of others in an impactful way, the experience is just all that more meaningful. Music is a universal language. It speaks to almost everyone in some significant way, and is a more powerful tool than we can even fathom. If we stand together for a cause, we can eradicate injustices in the world and innovate the future.
- Ashley Avicolli, University of Miami
BeachGlow has a definition. BeachGlow is when people gather at one place and have the opportunity to show excitement, energy, and fun at an event where we listen to great music and help donate money to organizations that need help.
- Tim Dischert, Bucks County Community College/Temple University
I was asked what BeachGlow meant to me, and at first, all I could picture was the music, the lights, the beach, all wrapped up in one. Then I thought a little deeper. BeachGlow is a chance to promote an organization that creates school music programs for underprivileged kids, while turning a regular summer weekend into a life-changing one; possibly turning strangers into family, and most importantly, for no matter how brief, forgetting the negative vibes in the world and only focusing on the positive ones.
- Thomas Murray, John Jay College
As a festival-goer, BeachGlow means a lot to me because it throws a big festival, and doesn't give the money all to the DJs nor to the staff, but to a good cause benefitting today's youth, and that's why I wanted to be a part of it!
- Joseph Alves, Montgomery Community College
I went to my first music festival in 2015, where I was introduced to a beautiful culture that revolves around peace, love, unity, and respect, otherwise known as PLUR. BeachGlow is the perfect example of what music festivals are all about - spreading positivity and giving back through the power of love and music. Combining a good setting, with good music and good people along for an even greater cause...it doesn't get much better than that.
-Marcella Solha, Union County College
BeachGlow is more than just a concert to me. Music brings people together and BeachGlow does this so perfectly, through the music and the cause. It's a charity event, but at the same time brings in top tier artists to perform.
- Douglas MacMaster, Temple University
For me, BeachGlow means more than a weekend of great music with friends. BeachGlow gives you the opportunity to not only listen to and see some of your favorite artists. It also gives you the chance to help others by enjoying yourself. What's better than that? I love the fact that BeachGlow is a concert for charity. You honestly don't hear of many organizations doing anything like that anymore. I am proud to be a part of this and I can't wait to share this with all my friends.
- Gwendolyn OConnor, DCCC
BeachGlow was an unforgettable weekend for me. Hands down my favorite part is how the money raised from sales goes back to kids and music programs. BeachGlow gives us a great weekend that provides us the opportunity to give back to the kids.
- Donovan Ross, University of Toledo
Concerts are one thing. BeachGlow is on another level. When there's a purpose for something as fun as a concert, and you know that being at that concert is benefitting someone else, then it's priceless. BeachGlow took the two things I love - the beach and concerts - and combined them to also benefit charity. The atmosphere is unlike any other.
- Marinelle Zarraga, University of Delaware
BeachGlow is amazing. BeachGlow is about raising money for charities, but also keeping festival goers happy and safe.
- Valerie Vu, Drexel University
Being a part of an event that's exciting and yet gives back to children is a very rewarding experience. The children are our future and what better way to support them than to party while giving back? With BeachGlow we can make major changes with the power of music!
- Keiyanna Wright, Delaware State University
BeachGlow is a beautiful music celebration. This event not only ensures a great time, but builds everlasting memories. It is a place to forget all your worries, make new friends, and get lost in the music.
- Andi Mayer, College of William & Mary


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Sometimes, but if I don't, it still makes for am incredibly moist bird. I don't brine so it works well for me. I have done different kinds of beer cans as far as the support goes. This one works the best for me and has produced the best chicken for me.
End of the day, alot of this stuff is just personal preference. This just happens to work best for me. That's half the fun in this art, playing around, trying new things and figuring out what works best for you. Personally, try a lot of stuff and think outside the box a bit.
I don't care how good you are at smoking, your job, etc., there's always something new to learn. Some may not agree with that, but it works for me.


Plastic Vacuum Forming Machine (also known as thermoplastic molding machine , automatic plastic blister forming machine or thermoforming machine ), we are one of the best vacuum forming machine manufactures in China
1. Ordinary semi-automatic machine forming mold is also workable for this machine , low mold cost.
2. Suitable for moderate quantity, automatic operation working environment, saving labor and mold cost.
3. Adopt the latest international thermoforming technology and It is integrated of electric, mechanical and pneumatic design.
4. PLC and Touch Screen Control, the whole system realize Human machine Interface.
5.Multi-stages heating, easy for the forming of Convex or Concave Moulds. Laser blade cutting.
6.Heating, punching, forming, cutting, stacking all-in-one machine. Reduce the worker,easy for operation,improve the production speed ,high automatic, it’s a idea machine for thermoforming products line production.
Biodegradable corn starch automatic negative pressure vacuum forming machine
It’s suitable for PLA、corn starch、PP、PE、APET、PVC、PETG 、PS、ABS 、EPS、HIPS and other plastic sheet forming, thickness from 0.1mm to 2mm .
Processing packages with high transparency, high depth, circular, square Shape, irregular, top and bottom both sides stretch, turnup etc. Used as medical industry blister lining、food and lunch box,toys, tray, dish, bowl, cover, electronic and other industrial packaging.
Automatic feeding→Top and bottom two stages heating→Negative pressure forming→ Hole punching(optional)→Cutting→Stacking→Conveyor belt transport→ Scrap automatic recycling
1) The system sets a number of protection measures, and each action that may collide with each other has a chain protection.
2) Safety door protection and sealing device adopts manual deduction and manual locking to improve equipment safety factor.
3) The electrical main control system is controlled by PLC integrated module, and the industrial touch display is used as HMI (human machine interface), and the Chinese interface is adopted. The machine has settings and modifications including button operation and all process parameters to make the unit easy to operate and maintain.
4) The working mode of the whole machine is divided into manual/automatic, all setting operations are realized on the touch screen; when the operator puts the materials, the automatic starting device is used to complete the whole process of forming the process, and the materials in the silo are directly produced; manual Mainly used for mold change or sample control.
5) The power distribution cabinet contains protection circuits, including overcurrent, overvoltage, undervoltage, short circuit and overload protection. The heating element has a fuse protection. For safety issues that may pose a hazard to the system or workpiece, there are warning signs or backup text instructions. Leave 5-10% space in the control box for future changes. The cabinet is equipped with a strainer and a protective cooling fan.
6）All non-removable cables and wires outside the power box are hidden in the cable trough for easy opening and repair. If it is not possible at this point, use a hose to fix it.