This is a headlamp kit that includes two replacement LED bulbs, and two control drivers. Drivers plug right into your existing vehicle harness. Ulight 6s uses a Edison DF-4BS LED and is a fan-less design. This is the latest 6s version which supersedes the V7. The LEDs on the blade are at the exact same depth as a standard bulb so that the light is reflected properly out of the fixture. Work with most Daytime Running Lights at they illuminate at 6 volts to 32 volts.
LED lights are brighter than stock, as bright as HID without the warm up time and use less power.
HEADLIGHTS DO NOT SHIP TO CANADA
Model 9004: Dual Beam (Low and High)
Lumens: Around 6000 per pair, a brighter light for you without blinding others.
Kelvin Color: 6000k
Ensure there is room for the heat sink on the back of your bulb in your vehicle. Beam pattern is adjustable by rotating the LED (hex key included). Non-vehicle specific instructions included.
Not sure what fits your vehicle? Here is a common lookup tool.
This is not a DOT compliant tested light, similar to HID modules. Your light fixture is DOT certified and the light control is very similar to your original halogen bulb. Please use at your discretion.
9 Reviews Hide Reviews Show Reviews
Worked beautifully! Great support and customer service. Thank you
This was one of the best up grades I've done so far to my motor home. Very bright and lights the road up well. Very easy install. Highly recommend.
These replacement Headlights are Fantastic. I installed these in my Volvo 740T
I had a tough time finding ones that fit then I stumbled on a blog and ordered right away.
Very very bright. Easy to install even in cramped space. Wish I had done it sooner.
I haven't got to try mine on the road yet but just shining across my yard they are crazy bright! The only thing that I would recommend is that you put on the 9004 light description, that you will need to cut your retainer ring or buy the one that you sell up front instead of in the installation instructions. Thank you. M4 Note: That is formation as well as a link are already in the product description at the bottom.
Product is beautifully made and easy to install, the light improvement over the old headlights is amazing.
your phone conversation about the led headlamp kit was helpful, accurate, and right on the money. i have already recomended your product and company to friends that respect my opinion. gratefully yours, al
I drive from Vancouver to Whistler BC once a week at night and I drove up the Monday night and I now can see. I don't need high beams now


text:
Silver CONCORD² Ear Cuff / Ring
Constructive ear-cuff that needs no piercing can be also worn as a ring, or even a nose ring. Hand made out of two rings and secured with pins. Looks impressive when worn in both ways - on the ear or on the finger. Small gap ensures secure hold and does't allow to slip off the ear.
An original design that nearly seems to be floating when worn, blending understatement and innovation. Impossible not to notice, you'll fall in love with these earrings from the first time you try.
- Composition: silver 925 or 18k gold plated silver 925
- Measurements: comes in two sizes: S - inside diameter 15mm; M - inside diameter 17mm
- Weight: ~4g
- Code: CECS008SS
- Comes in a designer-stamped box.
- All pieces have been certified in accordance with the Lithuanian Hallmarking Requirements.
- MIUTTO.COM is a registered member of Lithuanian Assay Office.

domain: design


text:
“They say that when penguins find their mate, they stay together for ever.”
Back in 2002 I found my penguin in a sea of UVMers. He stood out like a shiny new penny. Cocky as hell, but I was intrigued. I knew there was a side he didn’t show most, and I would be the one to see it. He picked me up at my sorority house, we double dated to Starbucks. Our first official date. His caramel macchiato filled the air, while I sipped on my peppermint mocha cooly. It was love at first sight, and I am so glad I trusted my instincts.
What we have been through together has tested us. What he has helped me through, and I him; there are no words, just gratitude. These moments have made us stronger and defined our love in ways I could have never thought possible. The bond created is one I didn’t think was available to have with a person not in your family; not your blood. But that is simply not true. We have made a family. I lean on him as I did my parents, as I know he does with me. Watching him on our wedding day, becoming a father, to achieving his dreams professionally, I consider myself so incredibly lucky he chose me to be his penguin in life.
Recently, we started working together. Many said, “Holy moly, how’s it going?” I can’t deny, I had my reservations, but again the highers above told me to chill and my fears were washed aside. Witnessing him command an audience of 100s is just awe-inspiring, and I hope our children get the spark that he has with others. I have fallen in love with him over and over again through this unforgettable experience. Yes, we have had our moments where I have wanted to ring his neck, but I find myself saying every time I feel that way, “Well, there is no one else I would rather argue, or ring their neck.”
I consider myself blessed to have found my forever penguin. Blessed to have made a family with this wonderful man. Sending love to you Jordi and thanks from the depth of my heart for what you do for me and our family!

domain: literature


text:
Day 1: Saigon - Cai Be - Phu An - Dong Hoa Hiep - Vinh Long - Sa Dec
Start at Cai Be Town Pier: 10.00 AM. Welcome on board and fresh towels are served. Journey begins with the visit to Cai Be colorful floating market, cruising among local barges full of fruits and vegetables. Visit to Ancient Mandarin House dating from 1890 with personal welcome by the House Owner. Stop at local home factories to observe the traditional procedure of making rice ice paste, coconut candies and other specialties.Proceed to Phu An Hamlet, an untouched beautiful area reflecting some of the best sights the Mekong Delta has to offer. Lunch at "Le Longanier", a superb Indochinese villa located by the River, in a lush tropical garden surrounded by fruit plantations. Cruise on Tien Giang River, one of the two largest arms of the Mekong. These evergreen islands among the Mekong River bring about large networks of meandering rivers with countless arroyos and remaining unknown to many people.Cruise on a small beautiful canal through water hyacinth plantations, followed by rowing boat for a cruise along a narrow canal passing by a local tiny village and fruit plantation. Visit further on the banks and visit one of the largest artisanal brick factory. Sa Dec Town appears as little “Venice” in the Mekong Delta with numerous narrow canals, and different kinds of trading activities.Disembark for a very interesting visit at a beautiful ancient house or “Nha Co” dating from the early 19th century, home of Ong Huynh Thuy Le, former “lover” of famous French novelist Marguerite Duras.A delicious dinner shall be served on board. Enjoy the first night on Mekong River. Overnight onboard.
Day 2: Sa Dec - Long Xuyen - Cho Moi
On-board breakfast at 7.00 AM. Disembark for a guided visit of the charming and peaceful town, walking along its narrow streets where beautiful French old houses, Chinese temples and Vietnamese Dinh are dating from the last century.Visit to the local market, one of the most attractive features in Vietnam.Back on board to cruise upstream to Long Xuyen, a peaceful provincial town located on the Mekong banks. The cruise passes by several luxuriant islands, countless sampan boats carrying sand, rice, fruits and vegetables, fishes, showing an intense activity on the river. Approaching Long Xuyen, lunch is served on board.Quick tour of Long Xuyen typical center before cruising further to “Cu Lao Ong Ho” (The Tiger Island) for a visit at Ton Duc Thang Museum, second president of Vietnam.Proceed upstream on the Mekong River to Chau Doc. Optional stops on the banks for cycling tours to discover deeper the inhabitants life style. Dinner at the Ancient House in the suburbs of Cho Moi.Back on board in private sampan for your second night on the river.
Day 3: Cho Moi - Chau Doc - Saigon
Early on-board breakfast while cruising to Chau Doc.Cruise on a little arm of the Mekong where several traditional activities can be observed on the banks (artisanal boat factories, bamboo baskets making, palm leaves cutting, net fishing), as well as old Vietnamese temples dating from late 19th century.Arrival at Chau Doc late in the morning. Located on the upper Mekong Delta, the town is 280 km south-west of Saigon onto the Cambodian border. With such proximity the local population is an eclectic mix of Cham, Khmer, Chinese and Vietnamese sharing different cultures and historical richness.Disembark at Chau Doc main city pier 11.00 AM. End of services.
- Song Xanh 1 (15m long x 3,5m wide, 1 living room transformed into a comfortable bedroom at night (15m2), 1 bathroom with wc, lavabo and shower, 1 sundeck at the back where chairs, table, and meals or drinks can be served)
- Song Xanh 2 (18m long x 3,5m wide, 1 bed room, 1 living room that can be transformed into 1 more bedroom at night (15m2/each), 1 bathroom with wc, lavabo and shower, 1 sundeck at the back where chairs, table, and meals or drinks can be served)
- Song Xanh 3 (18m long x 3,5m wide, 1 bed room, 1 living room that can be transformed into 1 more bedroom at night (15m2/each), 1 bathroom with wc, lavabo and shower, 1 sundeck at the back where chairs, table, and meals or drinks can be served)
- Song Xanh 4 (18m long x 3,5m wide, 1 bed room, 1 living room that can be transformed into 1 more bedroom at night (15m2/each), 1 bathroom with wc, lavabo and shower, 1 sundeck at the back where chairs, table, and meals or drinks can be served)
* Each sampan will carry a charming rowing boat ("Xuong"), nicely designed for deeper cruises along small canals and arroyos during the itinerary.Descriptions:
* Bicycles can also be taken on board (fixed on a rack a the back) for exciting "out of the track" countryside rides.
* Designed for individuals looking for authentic "Private Cruise" experience, with overnight on board. Exclusive itineraries 2D/1N and 3D/2N.
Equipped with a bathroom with lavabo, wc and shower, the sampans can also be used for daily private cruise programs for FIT's or Groups.
"Song Xanh I": 15m long x 3,5m wide (1 living room transformable into 1 bed room at night) / Capacity max. 2 adults - "Song Xanh II & III & IV": 18m long x 3,5m wide (1 bed room + 1 living room transformable into 1 more bed room at night) / Capacity max. 4 adults + 1 or 2 young childrens.

domain: geography


text: Voltaire once wrote: ‘Being galant in general means seeking to please.’ By the 18th century, ‘easy listening’ music for the emerging middle classes had become big business for composers. Lightly accompanied sonatas with charming melodies embodied the galant style. These were often scored flexibly so they could be played whatever instrument was available in the home. In this generous selection of six sonatas (three by Telemann, two by J. S. Bach and one by C. P. E. Bach) only one was originally scored for bassoon. No matter, for they are all played convincingly by Matthew Wilkie, the principal bassoon of the Sydney Symphony, ably accompanied by Neal Peres Da Costa and Kees Boersma. (Using a bass rather than a cello is unusual but plausible.) Warmth and clarity are appealing hallmarks of Wilkie’s tone, whether in the technically demanding faster movements or in the languorous and sensitively performed slower sections. Far from being the ‘clown of the orchestra’, here the bassoon is suave, expressive and very pleasing indeed.

domain: artistic


text:
To a journalist, section 2b of our Charter of Rights and Freedoms, which guarantees freedom of the opinion and freedom of the press, is the foundation of all that they do. This privilege carries with it a responsibility to inform us, the public, on matters that affect us.
The dismal handling of and communications about the garbage pick-up situation in our town is a perfect illustration of why the use of Facebook and other types of social media to inform the public is a poor substitute for meaningful news reporting.
A large volume of information and misinformation is disseminated via the Hope Facebook page on many issues affecting the people. Sadly, this is typical of Facebook in general. As has happened time and time again in our town, when an issue of importance comes up, people moan about it on Facebook. Some may go so far as to create a Facebook page and group about the issue. Feeling all warm and fuzzy inside about having done so, they then walk away feeling that they have accomplished something, when in fact, they really done little of substance.
As has been well documented, those who choose to subvert our freedoms and spread bigotry often use Facebook as their channel of communication. While the people who comment on the Hope Facebook page do so only with good intentions, it should always be remembered that everything there is unverified and unconfirmed. So many times, it driven by rumours and statements like “I heard that…” and “They say…”
It is unfortunate that as the Hope Facebook page is public and does not require one to join Facebook, it has become a primary and immediate source of news for our town, when this job should fall on the shoulders of the fifth estate, our community newspaper, The Hope Standard.
While the Hope Standard does have a regular public website, news is not updated as frequently as it should be. The alternative provided is to visit The Hope Standard’s Facebook page or Twitter. Therein a problem is presented, for to read the latest Facebook posts from The Standard, one has to join Facebook.
It is shameful that the newspaper requires a person to join a website simply to be informed and get factual news reports. Do you, The Hope Standard, not realize that some people, such as myself, have no desire to join Facebook? To place news there is a shirking of the responsibilities of the time honoured tradition of journalism.
You must realize that we have no other reliable outlet for news. Radio stations such as Star98 have no desire to report news as playing the latest by Lady Gaga or Cardi B is that matters to them. Television news is all Vancouver-centric. Isn’t it time that you stopped feeling all “warm and fuzzy” inside because you placed news on Facebook and Twitter and began practicing the type of journalism that our Charter of Rights and Freedoms has afforded you the privilege to provide.
Anthony G Pavick

domain: news


"We emulate nature in that way," say industry sources involved in the development and manufacture of loitering munitions, the relatively new and highly lethal category of unmanned airborne vehicles that depart on a mission but never return to base. They are designed to spot, identify, attack and kill – a UAV that is 100% warhead.
Dani Eshkar, VP of Aeronautics – which unveiled their K1 loitering UAV at the last Paris Air Show – explains the operational need: "When you launch a ballistic charge or a missile at a pinpoint target, the missile will hit the mark and destroy it. But what if the target in question disappears and hides – a target that has been visible suddenly disappears and pops up again, (what if the target is) a non-static target? This is consistent with asymmetrical warfare: an enemy detachment advances on foot or in a vehicle, hides and pops up again. A single person hides in dense vegetation or in the trees and suddenly pops his head up – the loitering missile will spot him, identify him and swoop in for the kill – just like an eagle. The thing about a loitering UAV is the fact that it waits for an opportunity, using a surveillance camera with a tracking feature, and then attacks by crashing onto the target."
The UVision Company takes this concept one step further. Their "Hero" loitering munition range belongs squarely on the future battlefield: a platform that maintains visual contact with the target ("Eyes on Target") and strikes when the opportunity presents itself, even if the target pops up for just a brief moment.
The next move forward will be made into the sea environment: UVision's CEO Yair Dubester told Israel Defense that they intend to unveil an unmanned surface vessel designed to launch small loitering munitions, as well as an unmanned ground vehicle capable of launching such munitions. "Launching loitering munitions from a naval surface vessel is a new concept. The Launching platform will not be sensitive to the motion of the waves, it will have neither a thermal nor an acoustic signature and launching will be possible even with the vessel pitching and rolling violently in rough sea conditions," says Dubester. The spearhead of UVision's loitering munition range is the Hero-120, which carries a 4.5 kg warhead.
Most of the UAVs and MUAVs developed and manufactured in Israel (and used with tremendous success by IDF and foreign armed forces) belong to the category of vehicles that return home after completing their missions. The developers' doubts and concerns always focus on the same characteristics required of any unmanned vehicle: to remain airborne for the longest possible time and carry a payload that would include everything required for photo-surveillance, video, recording and communication – all in order to collect the maximum amount of intelligence within the shortest possible time to the highest quality standards and deliver it promptly, accurately and reliably to the users.
Tzvika Naveh of the Innocon Company had this to say: "Our Spider is a highly advanced UAV. Carried by a single trooper, it weighs 20 kg, has a payload with day and night (surveillance) capabilities and takes still photographs. It was designed for "over-the-hill" missions and has a robust construction and a quiet electrical motor. It can remain airborne for two hours at an altitude of 15,000 feet and has a range of about 10 kilometers. These are the requirements to be met by a tactical UAV operated by a single trooper on the battlefield." The Company has recently received an order for a modern UAV system from the Thai armed forces. The new system should be able to monitor the target area for more than 20 hours and feature automatic take-off and landing capabilities. Innocon is mainly involved in the development of software elements (control systems for unmanned vehicles, Micro-NAV navigation systems, GPS systems and software for ground control stations) for the platforms manufactured by the major industries.
UVision also focuses on UAVs/MUAVs for tactical and strategic applications. For example, their Hero-30, the smallest model in its category, carries a 0.5 kg warhead, has a speed of up to 100 knots, a total weight of 3 kg, a range of up to 4 km and an endurance of 30 minutes. It is a portable UAV operated by a single trooper. Conversely, their Hero-900 model was designed for strategic operations. It carries a 20 kg warhead, has an endurance of 7 hours and an exceptionally long range – up to 250 km.
The Blue Bird Company has recently unveiled an upgraded version of their Thunder-B UAV, which is a small platform offering the capabilities of a larger system. Itay Toren of Blue Bird: "The upgraded platform has carved a new niche in the small, tactical UAV category. It has an endurance of up to 24 hours, an extended range of 150 km, smart avionics and a diversified range of payloads, which can include a 3-axis gyro stabilizer and a laser pointer, along with the option of carrying two payloads." The Thunder-B UAV is operated by a team of two to three troopers. Launching is automatic, using a pneumatic catapult, and the UAV is recovered by means of a built-in parachute.
The UAS Technologies Company incorporates specialized technologies in its systems. For example, they use anti-icing systems in the event that their UAVs are to be employed under extreme weather conditions. They also offer servo motors and systems for landing their UAVs on board naval vessels. UAS Technologies flew their smallest UAV, UAS-20, for the first time in 2011. This UAV has a speed of 42 knots, a range of up to 100 kilometers and an endurance of 24 hours.
The Top I Vision Company supplies surveillance aerostats and their Casper-20 UAV to clients in Israel and around the world. CEO Nir Chantal told us: "There is a growing demand, worldwide, for our aerostats, mainly because of the payloads that offer new electro-optical and SigInt (Signals Intelligence) capabilities."
The Company's surveillance aerostats are in use by IDF and the specialist counterterrorist unit of the Israel Police, as well as for TV broadcasts. They were used during Independence Day events as well as during the visits of the Pope and the US President to Israel and in many other countries. The aerostat may be towed by a Jeep and the average height of the platform is about 100 meters. Nir Chantal believes that "In the field of UAVs everyone knows how to do everything. In order to succeed, however, you are tested by your business flexibility – whether you can fulfill the order in accordance with the client's requirements, and whether your delivery intervals are accurate and short – that is how you must operate under such fiercely competitive conditions as the ones that exist in our field of business in Israel."
The Steadycopter Company focuses on Rotary Unmanned Airborne Vehicles (RUAV) and develops the Black Eagle 50 RUAV for military and civilian applications. Their RUAV provides surveillance images of expansive, remote areas. The Company website explains that RUAVs are ideal for maritime missions. The major advantage of such platforms is their ability to take off and land from/on board naval vessels, reach high-risk areas, hover at a low altitude while using their sensors or fly at a high altitude while directing military forces or emergency services in natural disaster situations. The Steadycopter Company refused to provide any additional information about their developments.
Underground Tunnel Surveillance
Quadcopters are the latest trend in the field of unmanned airborne vehicles. Today, civilians can purchase small, compact quadcopters for photographic purposes. Larger platforms are suitable for both military and civilian applications. The Flying Production Company offers the Da Vinci multi-rotor hexacopter – a short-range surveillance system for over-the-hill missions on the battlefield as well as for use in disaster areas and in agricultural applications. Ofir Zikri of the Flying Production Company reveals that the Company has recently embarked on the development of a small, smart vehicle with multiple capabilities that would provide a solution for the subterranean challenge, namely – underground tunnel surveillance. The 6-motor Da Vinci hexacopter has recently been provided with new, secure operation capabilities: navigation without GPS, encrypted communication and enhanced survivability under extreme field conditions. Ofir Zikri had this to say about their method of operation: "The hexacopter will follow a predetermined flight plan to the target, hover above it, the surveillance camera will be activated with GPS support, and at the conclusion of the mission the vehicle will fly home and land." In many countries, the hexacopter is licensed to fly beyond visual range. The Da Vinci hexacopter is used by the Israeli defense establishment as well as overseas, but no other details were provided.
Tethered hovering platforms are UAVs to all intents and purposes, except for the fact that they are tethered to a ground station or to a towing vehicle. The Hovermast platform by the Sky Sapience Company is used by IDF as well as overseas for military and civilian missions. Limor Barak, marketing manager at Sky Sapience, said: "We manufacture several models of the Hovermast platform, which transmits video in real time. We are currently developing a version that may be deployed over a naval vessel, as well as a low-cost civilian commercial version, without a payload, designed, for example, for guarding parks where rhinos are kept against illegal poachers." Barak said that the Company has recently signed a cooperation agreement with IAI for the joint development and manufacture of tethered hovering surveillance platforms, involving IAI's US-based subsidiary. The platforms are made of composite materials and are hermetically sealed. "The Hovermast is a platform that may be towed by a vehicle while it is airborne. It can be moved around while providing imagery from a level of dozens of meters. It can see many miles ahead, during the day and night, identify map references and provide surveillance support to troopers, vehicles and ground combat platforms." The cable linking the hovering platform with the towing vehicle supplies the platform with the energy it requires and contains the communication and data link. The platform is stabilized and the payload it carries may include surveillance cameras, a radar system, laser pointers, communication relaying systems, cellular communication antennae and hyper-spectral sensors. It can record ElInt and ComInt data – all according to the client's needs and requirements. Whereas it is not regarded as an airborne vehicle, it is not subject to any aviation regulations that restrict the use of UAS.


PVANET-HOUGH: DETECTION AND LOCATION OF CENTER PIVOT IRRIGATION SYSTEMS FROM SENTINEL-2 IMAGES
Keywords: Center Pivot Irrigation Systems, Object Detection, Deep Learning, Convolutional Neural Network, Hough Transform
Abstract. Irrigation systems play an important role in agriculture. As being labor-saving and water consumption efficient, center pivot irrigation systems are popular in many countries. Monitoring the distribution of center pivot irrigation systems can provide important information for agriculture production, water consumption and land use. Deep learning has become an effective method for image classification and object detection. In this paper, a new method to detect the precise shape of center pivot irrigation systems, PVANET-Hough, is proposed. The proposed method combines a lightweight real-time object detection network PVANET based on deep learning and accurate shape detection Hough transform to detect and accurately locate center pivot irrigation systems. The method proposed in this paper does not need any preprocessing, PVANET is lightweight and fast, Hough transform can accurately detect the shape of center pivot irrigation systems, and reduce the false alarms of PVANET at the mean time. Experiments with the Sentinel-2 images in Mato Grosso demonstrated the effectiveness of the proposed method.


text:
We often take pictures or shoot videos at library events to use in library publicity materials and on our website. Please view our policy.
For further information, please contact the Rensselaer Library, 866-5881, the DeMotte Library, 987-2221 or the Wheatfield Library, 956-3774.
Between the hours of 9:45 & 10:45 am, Clinical Home Health Care of DeMotte will be offering free blood pressure and glucose screenings, as well as $5 total cholesterol screenings at the Wheatfield Library. No appointment is needed.
For information, visit or call the Wheatfield Library at 956-3774.

domain: medical


text:
Michael Jackson was born on the 29th of August 1958 in Gary, Indiana. He was the 7th child out of nine children’s in the family which was fathered by Joe Jackson and mother Katherine Esther. Michael grew up in a poor family where they had to struggle for a living. At such a young age Michael was the lead singer in the group Jackson 5 which consists of the entire Jackson brother which was formed in 1964. His dad, Joe Jackson whom was their tutor, teacher and mentor at that time always pushed them to go further in the group’s musical career.
The Jackson 5 uses to perform in many small bars, clubs and competition in their area where they came from that is Gary, Indiana. His dad was a strict vocalist teacher. As a head of the family, his father that is Joe Jackson use to mentally torture Michael Jackson when he does mistake while singing. In a way this has helped Michael to be a good singer which has developed a voice that suits many types of generation not only the young but also the older people. His father’s nature in scolding and mental torture has somehow scared his childhood days which have affected him until today. But that did not stop him from producing multimillion selling records worldwide. He started out small and went big into the music industry touching many people’s hearts with his incredible music which all aged group could gather and watch it out together. So what else can we say about the King of Pop, his magnificent, his black and white, and he can dance like no man else can, and his dance moves are all created and improvised by him. He is a living legend by himself and no one can deny that.
When I arrived at California, I was picked up by Michael’s chauffeur and his personal assistant to his home in Santa Barbara County. As soon as I stepped into his ranch, I was amazed on how huge was it and on top of that how beautiful was it. I was served with coffees and pastry while waiting for Michael Jackson to be ready. As Michael Jackson came and sat down, we had a few light conversation and drinks before I actually run through the main interview. He was so friendly and loves to joke around. I asked Michael Jackson, “How does it feel to be a real king?” And he simply replied with a big smile on his face, “I never try to think hard about it because I don’t want it to go to my head. But, it’s a great honor.” And I added that it’s great to hear that Michael Jackson actually answered it calmly with a big smile on his face despite being the legend King of Pop in the world. I went on to ask Michael Jackson about his recent birthday celebration and how he feels to be 50 years old. Michael Jackson said, “I can still do my famous dance moves and more despite my age.” He also added that he feels very wise and sage but at the same time very young in mind. To be at that age, and still look young and healthy, it’s a great thing for Michael Jackson, because looking at his physical side; he does not even look like 50 years old.
Looking at Michael Jackson’s achievements in his albums like Dangerous, Thriller, and Off The Wall, he made multi million dollars in revenue and it was the best selling albums of all time. So I had to ask Michael Jackson to pick a single song as his greatest achievement. He replied, “Oh boy, that’s a hard one.” He continued, before singling out “We Are the World,” “Billie Jean” and “Thriller.” But Jackson was not content to rest on his laurels, saying, “I am still looking forward to doing a lot of great things.” This shows Michael Jackson was not going to sit down and shake his legs even though he has made fantastic albums but still presses on to do even more intriguing albums in the future. I really envy his determination at that particular point of time when he answered that question. Michael Jackson also said that he hopes to release new music and there are no particular dates set for it. As for now, he is still writing songs and loves composing music and at the same time loving his time raising his children plus enjoying every second of it.
I then continued asking Michael Jackson, “Would you like to your two sons and daughter to have the same sort of upbringing as you?” Michael Jackson then said he prefers that his children to enjoy their childhood as much as possible since he did not have a proper childhood when he was their age. It was due to the pressure he endured at such a young age and had to balance his stardom and career together and it was not easy for him at all. Michael Jackson then added, “I let them go to the arcade and go to the movies and do things,” he said. “I want them to get to do the kind of things I didn’t get to do. So, I fill them with a lot of enjoyment that way it’s a lot of amusement.” Then at that moment, a question arise within me and I directed it to Michael asking him whether his children has love for music. He replied, “The kids love music and they too are very much into arts but then I do not push them so much into it.” Michael Jackson then added on that if he could go back in time to give some advice to himself at the age of 9 or 10 that is nearly his oldest son’s age, he would advise himself, if he is going to do it he better commit himself and know his craft plus get really involved in it. He continued that he had to have rhinoceros skin to deal with the pressure of fame. It is not easy being who he is.
The last question I asked before i concluded the interview was, “Where is all this heading too meaning your fame, stardom, and life?” Michael Jackson replied “I really believe that God chooses people to do certain things, the way Michelangelo or Leonardo da Vinci or Mozart or Muhammad Ali or Martin Luther King is chosen. And that is their mission to do that thing. And I think that I haven’t scratched the surface yet of what my real purpose is for being here. I’m committed to my art. I believe that all art has as its ultimate goal the union between the material and the spiritual, the human and the divine. And I believe that that is the very reason for the existence of art and what I do. And I feel fortunate in being that instrument through which music flows. Deep inside I feel that this world we live in is really a big, huge, monumental symphonic orchestra. I believe that in its primordial form all of creation is sound and that it’s not just random sound, that it’s music.” I was very pleased and happy on the way Michael concluded his last question. To be the King of Pop, he was not even arrogant, rude, or sarcastic but instead he was calm, warm and friendly. The interview went smoothly all the way and I was very excited and amused by Michael Jackson’s personality and style when he was answering my question. Of course I could not resist myself in taking a few pictures with him and also getting my t-shirt signed by the legend and one and only King of Pop who will continue to change people’s life in many ways.
Disclaimer: R.I.P for Michael Jackson, this articles is for assignment purposes only, thanks everyone.

domain: celebrity


text:
From Our Special Correspondent
Daijiworld Media Network
Bengaluru, Jul 19: Political circles are agog with speculation over the likely resignation of Chief Minister B S Yediyurappa, who will be completing two years in office on July 26, possibly on July 28.
The Chief Minister, who went to Delhi last week and met Prime Minister Narendra Modi, Union Home and Cooperation Minister Amit Shah, Union Defence Minister Rajnath Singh as well as BJP National President J P Nadda, has already announced that the State BJP Legislature Party meeting will be held on July 26 to mark the second anniversary.
According to informed sources, the 78-year-old Yediyurappa is likely to announce his decision to relinquish office. However, in politics, last minute changes cannot be ruled out as without Yediyurappa’s willing consent, the going may not be smooth for the newcomer.
State BJP President and Mangaluru MP Nalin Kumar Kateel’s reported audio clip on Yediyurappa’s resignation, though denied for the record, is said to be not far from truth.
Yediyurappa has been the most prominent exception to the unwritten rule in the BJP after Modi came to power in 2014 that political leaders will not be allowed to continue in office upon reaching the age of 75 years.
Influential leaders from the politically powerful Veerashaiva or Lingayat community such as Basavaraj Patil Yatnal, who hails from Vijayapura, Aravind Bellad from Dharwad or the present Mines and Geology Minister Murugesh R Nirani from Bilagi in Bagalkot district are said to be front-runners for the coveted post. Of the three, Yatnal and Bellad have been openly gunning for Yediyurappa and demanding change of leadership while Nirani is Yediyurappa’s staunch supporter.
The ruling party, which enjoys a strong following from the Lingayat community to which Yediyurappa belongs, wants to consolidate its hold over the community as the other dominant community of Vokkaligas is divided between JD(S) supremo H D Deve Gowda and his son H D Kumaraswamy and KPCC Chief D K Shivakumar, who is also a Vokkaliga.
The Congress party also has Siddaramaiah, who belongs to the backward Kuruba community and has support among backward classes, while senior party leader Mallikarjuna Kharge, who is the party leader in Rajya Sabha, enjoys the support of the Dalits. However, the BJP hopes to win over the other communities including Dalits. BJP is believed to be not so sure of Ministers R Ashok, Dr C N Ashwath Narayan or C P Yogeshwar, who are Vokkaligas, winning the support of the community. Former Chief Minister and former Union Minister D V Sadananda Gowda, also from the community, is unlikely to be chosen. Senior BJP leader and former Chief Minister Jagadish Shettar or Home Minister Basavaraj Bommai, both Lingayats, and K S Eshwarappa from the Kuruba community are said to be not in the race.
Political observers believe that the party high command has convinced Yediyurappa to honourably step down to pave the way for his successor to prepare the party for the ensuing assembly polls in the State in 2023 and also the Lok Sabha polls in 2024.


A motorcyclist was taken to hospital with serious injuries after a one-vehicle crash in Buxton.
It happened at around 4.30pm on Monday 3 August on the A5004 Manchester Road, just past the layby at the top of the hill as you come out of Buxton, before the bend.
Police believe just one vehicle, a motorbike, was involved.
The man, who was riding the motorcycle, suffered serious injuries to his hand and was taken to hospital for treatment.
Officers would like to hear from anyone who witnessed the collision, or if they were travelling along Manchester Road in either direction around the time and may have dashcam footage.
You can get in touch using one of the following non-emergency contact methods, quoting reference number 20*400396 and name of the officer in the case, PC Kirsty Wallace-Parr, in any correspondence.
- Facebook – send a private message to /DerbyshireConstabulary
- Twitter – direct message the contact centre on @DerPolContact
- Website – complete the online contact form at www.derbyshire.police.uk/Contact-Us.
- Phone – call 101.
You can also call Crimestoppers anonymously on 0800 555 111.


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Married on August 5th, 2011, Maria Miller, Director of Catering at The Hills Hotel, wanted to give Kathy and Elliott their custom painting as a surprise just before the ceremony to use as decor on their guestbook table. I can’t believe how lucky I was to be able to give it to Kathy personally – a dream come true for me!
Maria reuested I capture the beautiful features of the hotel’s newly remodeled Crystal Ballroom and it’s key decor elements and colors of Kathy and Elliott’s dream wedding. Kathy fell in love with the venue – the purples, chandeliers and picture frame decor. All the of the photos were provided about 6 weeks prior to their wedding…
Kathy’s dress was flowy with unique accents like rows of ‘feather’s and a twisted ruched sweetheart neckline.
Kathy and Elliott have their whole life ahead of them. Thanks to The Hills Hotel, they will have a keepsake from their wedding that will last their lifetime that they can pass on to their children some day to remember their parents’ special day.
Venue | The Hills Hotel, Laguna Hills (CA)
Photography | Miss Darcy Photography, Darcy Fehringer
Which textured memories do you treasure?


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|Plot Summary of The Wind-Up Bird Chronicle |
The story starts off simply enough about Mr. Okada losing his cat, then his wife, and then finally his own mind. In a bizarre fashion all of the odd characters and situations that Okada finds himself in are all related in some way which is eventually summed together at the end. What was most fascinating is the elements of Buddhism, the search for nothingness to really get in touch with one's consciousness. Okada finds the strength and ability to achieve 'emptiness' at the bottom of a dark well. In the well, the author puts us in touch with the most bizarre adventures in Okada's consciousness.
Much of the story talks about war guilt.
This synopsis report prepared by David G. Phillips
|Chapter Analysis of The Wind-Up Bird Chronicle |
Ratings are on a 1-10 scale (Low to High)
Time/era of story
Inside culture (main char)
- conduct in war
Is this an adult or child's book?
- Adult or Young Adult Book
Outside culture (society)
Coping with loss of loved one(s)
Has magical powers?
Magical/mental powers of main character:
How much descriptions of surroundings?
- 8 ()
Small town people:
- nice, like Andy/Opie/Aunt Bee
Sex in book?
What kind of sex:
- actual description of hetero sex
Amount of dialog
- significantly more dialog than descript
Note: the views expressed here are only those of the reviewer(s).
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An interview with George W. Bush and his wife has surfaced that appears to show the former President admit what actually happened on 9/11.
The video shows Diane Sawyer ask Bush to compare the Boston bombings to 9/11, and the ex-President immediately starts to fumble.
“I don’t know all the facts, I don’t think we know all the facts, but I was deeply concerned that this could have been another conspira-…another organized attack on this country,” he says.
Bush was clearly about to call 9/11 a conspiracy, but he catches himself before he finishes the word. When he starts to say “conspiracy,” Laura’s eyes flash at her husband as if he has just spilled a deep secret.
It’s always been obvious that the government has been hiding the truth behind 9/11 from us, and this appears to confirm that there is still a lot that we do not know about the attacks.
What do you think about this new revelation? Sound off in the comments below!

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but the folks he’s messaging are people who have not announced in their own pages, the device understand can alter correctly. The web page isn’t going to show your women which can be enthusiastic about relationship or long-range affairs. Whichn’t get existed actually five or seven years back.
The initial technological incarnation on this is this notion of behavioral coordinating. Let’s say you happen to be a 30-year-old female therefore join accommodate. The two inquire, “Do you enjoy men with facial hair?” Your say, “yes” or “no.” The second method to verify that you love guys with undesired facial hair might possibly be never to ask you clearly but to just discover how your act on the website. Are you currently hitting countless kinds of dudes with beards? Perhaps you are. Maybe that might treat one understand that, simply because you usually perceived by yourself as somebody that can’t sit undesired facial hair. I believe that’s the kind of factor that tech are able to vow right now and much more someday.
Thus, dating sites can perhaps work even when whatever you feel or talk about we desire in someone is not always exactly what winds up getting optimal or most compatible for us?
One of the things that online dating sites managers will always content to let you know is that everyone is truly
awful assessors of who they really are and what they desire. I believe to some extent that’s true, but we’ll surely getting witnessing a perform that up as far as possible, “You need to get my favorite innovation in order to really determine what you probably decide!”
Clear of the technological innovation, just what enjoys taken place socially during the last decades and a half to make everyone need and want the decision and controls that online dating services grants as part of your?
The marriage age helps to keep receiving afterwards and later. The additional the marriage period drives up, the better this implies that men and women is internet dating in their old age. The larger that individuals are internet dating to their later years, the heavier it is for any folks to see. This is certainly just a real possibility of daily life. As you grow senior, for almost all someone, you are cultural sectors can shrink somewhat. Online dating services comes to be very beneficial. The internet relationship business provides noticed this comprising the 50 and also over group growing to be one of the most preferred class.
Will there be still a stigma, do you believe?
You will find a lingering mark. But, I reckon which extra online dating services increases a reputation if you are successful, the greater amount of the stigma will erode. We chatted to on the internet daters within the period range, men and women, all over the land. I would inquire further about how these people thought about the mark. The thing we heard a great deal was actually, “It seems like people are https://besthookupwebsites.net/twoo-review/ still stressed to fairly share it. But, you’ll take a small grouping of customers once one individual brings up the topic, there is this outpouring of talk about they. Everyone wants to share regarding it, but they dont always plan to be the best individual take it up.”
What exactly are online dating sites executives carrying out to try to get reduce a stigma?
The majority are looking to have online dating services industry in a fresh direction by putting a whole new brand over it. As opposed to calling it dating online, brand new web sites are being recognized as “social finding internet sites.” It is actually fundamentally social networks with an all new twist; simply injecting it utilizing the centre of online dating, and that is meeting consumers your don’t have found that on line.
Let’s start off with the pluses. Just how possesses dating online earned interaction best?
It is generating human dating simpler to see. Loneliness is actually an awful affliction. I think we have all withstood they at some stage in our everyday lives, and we figure out what that is definitely like. In my opinion a technology that comes along and states, “Hey, we have a response to that particular crisis” is a wonderful thing.
Dan Winchester, founder of a zero cost dating site in the United Kingdom, claims, “The outlook will discover more effective interaction but extra divorce case.” This seems difficult to understand.

domain: sociology


text:
Duct ectasia (DE) and periductal mastitis (PDM) are the most common benign breast conditions seen in women. The etiopathogenesis of these entities is still not clear and most of the theories regarding the causation are based on the histological features as seen on light microscopy. The ultramicroscopic features associated with these conditions that may give more insight to the etiopathogenesis are unknown.
To study the ultrastructural changes occurring in mammary duct cones in patients with DE and PDM using Transmission Electron Microscopic (TEM).
Major ducts removed by radical duct excision from 21 patients with final histopathological diagnosis of DE and PDM were subjected to TEM study with 2 normal duct samples as controls.
The TEM features of DE were denudation of the epithelial cells with focal loss of microvilli, widening of the inter-epithelial junctions with focal disruption of the T bars, periductal collagenisation without inflammation, and features suggestive of Epithelial Mesenchymal Transition (EMT). PDM features are intact epithelial lining with proliferative epithelium and periductal collagenisation with inflammation.
Citation: Ramalingam K, Vuthaluru S, Srivastava A, Dinda AK, Dhar A (2017) Ultra structural changes occurring in duct ectasia and periductal mastitis and their significance in etiopathogenesis. PLoS ONE 12(3): e0173216. https://doi.org/10.1371/journal.pone.0173216
Editor: Pei-Yi Chu, Fu Jen Catholic University, TAIWAN
Received: August 17, 2015; Accepted: February 7, 2017; Published: March 8, 2017
Copyright: © 2017 Ramalingam et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Data Availability: All relevant data are within the paper and its Supporting Information files. It can also be accessed from the following: https://datadryad.org/resource/doi:10.5061/dryad.528tv.
Funding: The authors received no specific funding for this work.
Competing interests: The authors have declared that no competing interests exist.
Nipple discharge among women is a common clinical entity. Duct ectasia (DE) / periductal masititis (PDM) is an important cause of this clinical condition. In spite of the enormous research, the etiopathogenesis and the structural pathological changes that take place in this condition are largely unknown. Literature is not clear as to whether DE and PDM are two different entities or different manifestations of a common clinical condition. A study of the sub cellular changes of DE and PDM may throw more light on these issues and may also provide insight into a specific target for local therapy if any, which is lacking so far.
To evaluate the ultra structural changes associated with DE and PDM by Transmission electron microscopic (TEM) study of mammary duct cones of patients with DE/PDM.
Materials and methods
Forty one consecutive patients with non bloody nipple discharge with clinical and radiological features suggestive of DE/PDM presenting to the surgical outpatient department of All India Institute of Medical Sciences, New Delhi were included in the study after obtaining Institute ethics committee’s approval and informed, written consent. Patients who had the following presentations were diagnosed to have duct ectasia- Presence of thick, colored, or creamy nipple discharge, thickened subareolar ducts, nipple retraction, and absence of signs of inflammation with sonographic features of dilated subareolar ducts and mammographic features of prominent ducts appearing as conical opacities with apex of the cone towards the nipple with or without characteristic coarse calcifications (ring like, lying on the duct wall or circular or needle shaped when the duct contents are calcified). Those who had history suggestive of previous episodes of subareolar sepsis, presence of pus/serous nipple discharge, and signs of periductal inflammation, tender palpable subareolar ducts, nipple retraction, and mammary fistula with radiological features of dilated ducts and subareolar abscess were considered to have periductal mastitis. Excluded from the study were those patients who were unwilling to give consent, women with bloody nipple discharge and cytopathology of nipple discharge smear demonstrating atypical or malignant cells. A detailed history and thorough physical examination were done for all patients along with ultrasound of both the breasts and axillae. For women who were above 35 years digital ammography was done. Cytopathological examination of the nipple discharge smear was carried out in patients with active nipple discharge. Patients who had active subareolar sepsis were treated with antibiotics prior to the surgery. Major mammary duct excision, the surgical procedure of choice was performed in all [S1 File]. The excised ductal tissues were processed for both light and electron microscopy. The histopathological features for making the diagnosis of duct ectasia were 3 or more dilated ducts with thickened or sclerosed duct walls, periductal sclerosis, hyperelastosis with or withoutepithelial denudationand no or minimal inflammation. The histopathological features for reaching the diagnosis of periductal mastitis were dense periductal inflammation and fibrosis with or without focal dilatation of ducts. Twenty patients who had pathological diagnoses of mixed duct ectasia/periductal mastitis with fibrocystic disease (n = 12), papilloma (n = 3), papillomatosis (n = 3) and tuberculous mastitis (n = 2) were excluded from the electron microscopic study. Based on the final histopathological diagnoses, 21 patients with definitive diagnoses of pure DE (n = 9), PDM (n = 7) or mixed features of DE and PDM i.e. duct ectasia with features of peridcutal inflammation (n = 5) were included in the TEM study [S2 File]. The tissues were fixed in 2.5% glutaraldehyde and processed by automatic tissue processor. Several resin sections were cut at approximately 1 micron using glass knives made by the knife maker and an ultra microtome. The ultrastructural examination was performed on Philips Morgagni 268 transmission electron microscope and Technai G20 transmission electron microscope. The normal mammary ducts sampled from 2 patients who underwent reduction mammoplasty were taken as control. These two ladies did not suffer from any nipple discharge and were premenopausal with regular menstrual cycles.
TEM study revealed the following features. The normal major mammary ducts showed a continuous epithelial layer (single or double layered) and myoepithelial cells interspersed in a discontinuous manner [Fig 1-A1]. Two types of epithelial cells lining the major mammary duct could be appreciated namely, the dark epithelial cells, being rich in electron dense ribosomes and the light epithelial cells [Fig 1-A2]. In the interepithelial junctions there were terminal bars [T bars] which were electron dense [Fig 1-A3]. The above mentioned findings correlated with the observations and the images documented in the TEM study of normal mammary ducts done by the various authors in the literature[1–4].
A1- This electro micrograph shows transverse section of the major duct with continuous epithelial layer [E] with underlying myoepithelial cells [denoted by arrow] which are discontinuous. L—Lumen of the duct. [x570]; A2- The above electro micrograph is a higher magnification of dark [DE] and light epithelial cells [LE], with dark epithelial cells showing dense distribution of ribosomes [Rb]. A3- This electro micrograph of a duct in the patient shows the presence of T bars in the inter-epithelial junctions [as depicted by the two arrows]. E- epithelial cell, L- lumen of the duct. [x5000].
In DE, there is flattening of the epithelium in the dilated duct in some areas with focal loss of microvilli of the duct epithelium & accumulation of intraluminal epithelial debris (seen in 9/14 (64.3%)). [Fig 2-B1]. While the cytoplasm revealed multiple membrane bound dark and light vesicles, [Fig 2-B2], and plenty of intracytoplasmic fibrillary structures, the nuclei appeared elongated—features suggestive of epithelial mesenchymal transition [EMT] were observed in 8/14 patients (57.1%) [Fig 2-B3]. T bars showed focal distortion [Fig 2-B4] with widening of the inter-epithelial junction were seen in 7/14 cases (50%) [Fig 2-B5]. Small ducts (ductules) [Fig 2-B6] showed similar epithelial changes as that of the major ducts with duplication of the basal laminae being observed in 7/14 patients (50%). Surrounding connective tissues showed marked periductal collagenisation (11/14 cases i.e. in 78.6%) with dilated lymphatic vessels [Fig 2-B7].
B1- Low power electro micrographic view of a dilated duct with periductal tissue showing focal denudation  of lining epithelium with intraluminal secretions[S] containing epithelial fragments [F]. Around the duct there is collagen deposition. [x1100]; B2- The epithelial cells in this show large number of vacuoles [V] and dense bodies [indicated by the arrows]. E- epithelial cell. [x5000]; B3- The duct epithelial cell [E] shown in the electro micrograph has elongated nucleus, intracytoplasmic fibrils [f] and intraluminal projections [indicated by the arrows] of the cytoplasm suggestive of mesenchymal transformation of the epithelial cell. [x3200]; B4- This electro micrograph depicts focal distortion of terminal bar [indicated by the arrow] and widening of the interepithelial junction [W]. E –epithelial cells. [x8000]; B5- This electro micrograph shows lifting of the epithelium from the basal lamina [arrow] and duplication of the basal lamina[D]. [x2550]; B6- The above electro micrograph shows periductal tissue filled with thick and thin collagen fibres indicative of active collagenisation. [x2550]; B7- Dilated lymphatic vessel [Ly] with the endothelial cell [En] in the periductal tissue seen in this electro Micrograph. [x1100].
In PDM, the epithelial cells were hypertrophic indicating active proliferation in 3 out 7 cases (42.9%) [Fig 3-C1]. The epithelial cell cytoplasm showed dilated mitochondriae with loss of cristae and prominent endoplasmic reticuluae suggestive of injury in 5 patients (71.4%) [Fig 3-C2]. There were numerous pinocytic vesicles in the cytoplasm of the epithelial cells suggestive of active secretion by the duct epithelial cells [Fig 3-C3]. However, unlike in duct ectasia, the inter-epithelial junctions were intact with preserved T bars in all the cases of PDM (100%). Periductal tissue showed neo-vascularisation secondary to inflammation in the periductal tissue in 3 patients (42.9%) [Fig 3-C4] & the fibroblast cells showed plenty of vesicles with abundant collagen granules suggestive of active collagenisation in all the cases (100%) [Fig 3-C5].
C1- The above mentioned electro micrograph shows transverse section of the duct lined by hypertrophic epithelial cells [E] almost filling the entire lumen [L] indicative of epithelial proliferation. BL—Basal Lamina. [x1100]; C2- The arrow in the above mentioned electro micrograph represents the inter epithelial junction. The epithelial cell shows dilated mitochondria with loss of cristae [M] and prominent endoplasmic reticulum [ER]. [x2550]; C3- The ultrastructure of the portion of the duct epithelial cell depicted in this electro micrograph shows numerous pinocytic vesicles [some fusing with the membrane—depicted by the arrow] suggestive of active secretion by the epithelial cells. The cytoplasm also shows large mitochondria with dilated cristae. [x13000]; C4- This electro micrograph shows capillary in the periductal tissue with plump endothelial cell and an inspissated red blood cell. This is suggestive of neovascularisation secondary to inflammation. [x3200]; C5- This electro micrograph shows a portion of a myofibroblast cell[MF] with lot vesicles [indicated by the arrows] containing collagen granules suggestive of active collagenisation. The cell also shows multiple dilated mitochondriae [Mi]. All these changes are indicative of exaggerated cell function.C—Collagen fibres. [x1550].
Immunohistochemistry [IHC] for Vimentin [A mesenchymal marker]: IHC for vimentin was done in 4 cases of PDM and 5 cases of DE. The epithelial cells in all the 5 cases of DE have showed focal areas of uptake of vimentin, which was not seen in cases of PDM [Fig 4]. This finding again supported the EMT which was observed on the TEM study of DE specimens.
There is no data available on the electron microscopic study of DE/PDM in literature. Hughes et al  have commented that there is no loss of microvilli in scanning electron microscope in cases of DE. However, no further details have been mentioned. Scanning electron microscopy as used by Hughes et al describes only the surface details while TEM describes in detail about the intracellular changes which helps us to understand the pathogenetic mechanisms better. In DE, the changes observed suggested EMT. EMT is an interesting biological phenomenon, by which epithelial cells get transformed into mesenchymal cells and acquire new characteristics such as motility and collagen synthesis. The EMT in duct ectasia has been substantiated by demonstration of vimentin positive cells among the normal epithelial cells in patients with DE and presence of epithelial cells with elongated nuclei and cytoplasmic processeses containing fibril like material. Thus EMT seems to may play a key role in the pathogenesis of DE. Though periductal collagenisation is seen both in DE and PDM, in PDM, the collagenisation is associated with inflammation unlike in DE. Thus, it is evident that DE and PDM may be considered as two different entities with two different pathogenetic mechanisms.
The etiopathogenesis of DE and PDM are poorly understood. The classical concept as enunciated by Haagensen and Ewing  considers duct dilatation under hormonal influence as a primary event. This leads to epithelium ulceration, followed by leakage of secretion into the periductal tissue leading to inflammation, secondary bacterial infection and periductal fibrosis. An alternative explanation by Dixon et al considers DE and PDM as two different entities & PDM does not precede DE.
These controversies can be addressed by the ultramicroscopic features of DE and PDM observed in the present study. Distinct changes in the epithelial lining and in periductal tissue in DE and PDM were observed on electron microscopy and immuno-histochemistry. In this study, pure DE was seen in nine patients, pure PDM in six patients and a combination of both DE and PDM i.e. DE with periductal inflammation in six patients. The combination of both being present together could be explained by the fact that there could be secondary duct dilatation following periductal fibrosis.
Identification of EMT changes in patients of DE in our study adds mammary ducts to the list of organs where in EMT seems to play a role in pathologically induced fibrosis [7–11]. However, the signaling pathway involved in EMT of DE is yet to be studied. Success of BMP-6 & 7 (inhibitors of EMT induced fibrotic process) in reversal of renal fibrosis in animal models [12, 13] is encouraging to conduct further research to identify the common switch of EMT in DE. Once the switch if any is identified, it may be turned off by molecular targeting and thuscure the disease.
Limited number of controls due to ethical reasons is a limitation of this study. However, the normal human major mammary duct ultrastructure that has been documented in the literature along with the present study controls aids us to compare the changes that have been observed in DE and PDM. Another limitation of the study which is common in any of the TEM study is that the small tissue dimension used may not be representative of the entire disease process.
As the electron microscopic findings of DE and PDM are distinct from one another, these can be considered as two different entities. The association of EMT in DE is a novel finding of the present study.
- Conceptualization: KR AS.
- Data curation: KR SV.
- Formal analysis: KR SV AKD.
- Investigation: KR SV AS AD.
- Methodology: KR SV AS AKD.
- Project administration: SV AS.
- Resources: KR AS.
- Software: KR.
- Supervision: SV AS AD.
- Validation: AS SV AKD AD.
- Visualization: KR AS.
- Writing – original draft: KR.
- Writing – review & editing: KR SV AS.
- 1. Ozzello L, Ultrastructure of human mammary gland, Pathology Annual, 1971; 6(1–59).
- 2. Tsuchiya S, Takayama S, Higashi Y, Electron microscopy of intraductal papilloma of the breast. Ultrastructural comparison of papillary carcinoma with normal mammary large duct. Acta Pathologica Japonica 1983; 33(1):97–11. pmid:6301211
- 3. Tsuchiya , Li F, Electron microscopic findings for diagnosis of breast lesions, Medical Molecular Morphology, 2005;38(4):216–224. pmid:16378230
- 4. Stirling John W. and Chandler John A., The Fine Structure of Ducts and Subareolar Ducts in the Resting Gland of the Female breast,Virchows Archiv, Volume 373, Number 2,119–132.
- 5. Mansel RE, Webster David JT, Sweetland H. Hughes LE, Mansel and Webster's Benign disorders and diseases of the breast. 3rd ed. London: Saunders Elsevier; 2009.
- 6. Haagensen CD. Mammary-duct ectasia; a disease that may simulate carcinoma. Cancer. 1951 Jul;4:749–761. pmid:14859196
- 7. Burns WC, Twigg SM, Forbes JM, Pete J, Tikellis C, Thallas-Bonke V, et al. Connective Tissue Growth Factor Plays an Important Role in Advanced Glycation End Product–Induced Tubular Epithelial-to-Mesenchymal Transition: Implications for Diabetic Renal Disease. J Am Soc Nephrol. 2006 Sep 1;17(9):2484–94. pmid:16914537
- 8. Kim KK, Kugler MC, Wolters PJ, Robillard L, Galvez MG, Brumwell AN, et al. Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix. Proc Natl Acad Sci U S A. 2006 Aug 29;103(35):13180–5. pmid:16924102
- 9. Chilosi M, Poletti V, Zamò A, Lestani M, Montagna L, Piccoli P, et al. Aberrant Wnt/beta-catenin pathway activation in idiopathic pulmonary fibrosis. Am J Pathol. 2003 May;162(5):1495–502. pmid:12707032
- 10. Zeisberg M, Yang C, Martino M, Duncan MB, Rieder F, Tanjore H, et al. Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition. J Biol Chem. 2007 Aug 10;282(32):23337–47. pmid:17562716
- 11. Zeisberg EM, Tarnavski O, Zeisberg M, Dorfman AL, McMullen JR, Gustafsson E, et al. Endothelial-to-mesenchymal transition contributes to cardiac fibrosis. Nat Med. 2007 Aug;13(8):952–61. pmid:17660828
- 12. Dudas PL, Argentieri RL, Farrell FX. BMP-7 fails to attenuate TGF-beta1-induced epithelial-to-mesenchymal transition in human proximal tubule epithelial cells. Nephrol Dial Transplant Off Publ Eur Dial Transpl Assoc—Eur Ren Assoc. 2009 May;24(5):1406–16.
- 13. Jenkins RH, Fraser DJ. BMP-6 Emerges as a Potential Major Regulator of Fibrosis in the Kidney. Am J Pathol. 2011 Mar;178(3):964–5. pmid:21356347


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Every thing was great about this place where I stop on my way to Myrtle Beach destination to rest from driving. Especially a great value for HH points. Very good breakfeast choices also. Room was clean and shower was new and receptionist was very hospitable. the lication was very quiet.
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What’s Inside the July 2011 issue of VeloNews
He may appear a bit boastful when he says “no one can drop me but Contador,” however, Radioshack’s elder statesman Chris Horner certainly backed up those words with his victory at the Amgen Tour of California. VeloNews managing editor Neal Rogers gives you the inside story behind the biggest race on American soil, including a race breakdown, interviews, awesome photography, and more.
In keeping with our recent bike tests, in the July issue we reach out to our female readers with our first-ever women’s road bike test. Rider/writer Rebecca Heaton and her crew put four women’s bikes and several pieces of hi-tech women’s apparel through the paces.
Photojournalist Gregg Bleakney files from the Giro d’Italia with an amazing behind-the-scenes pictorial of Italy’s grand tour.
In an eight-page special mountain bike section, Singletrack.com editor Jamie Bate takes an in-depth look at the evolution of the sport of mountain biking with a focus on the wild popularity of endurance races around the country.
Tech editor Nick Legan reviews some of the hottest aero gear for your time trial rig, and Ainsele MacEachran shares some secrets on how to get to the front in your next crit race.


Final piece of aquifer plan approved
Conservation funding now set; bills going up.
In a brief, anticlimactic ending to a painstaking, four-year-long process, the Edwards Aquifer Authority board voted Wednesday to approve the funding for a habitat conservation plan that should keep the region's main aquifer under local control.
The vote was delayed for two weeks because of a dispute over the EAA's policy of granting rebates for pumping rights that weren't used.
During a pair of meetings since then, however, several key people were able to devise a compromise that allowed the EAA board to vote unanimously and without discussion on the funding plan Wednesday.
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The EAA will play a large role in carrying out the plan, which was developed by the Edwards Aquifer Restoration Implementation Plan group with stakeholders from across Central and South Texas that depend on the aquifer or the water that flows from its springs.
Chuck Aherns, vice president of water resources and conservation at the San Antonio Water System, praised the “positive process” that led to the historic agreement.
SAWS was not a fan of the rebate system, since it uses most of its pumping rights and so subsidized rebates to cities with excess rights, like New Braunfels and San Marcos.
The final funding hurdle was resolved the way many of the thorny issues facing the EARIP group were over the past four years, Aherns said. While there often was disagreement among the 26 members, the group was able to keep the big picture in mind while forging compromises.
The EARIP was formed to develop a plan to protect the federally listed endangered species of Comal and San Marcos springs that depend on downstream flows from the aquifer while still preserving the interests of those who pump water from it, including cities, farmers and industries.
The group was formed in response to a federal lawsuit filed two decades ago.
Had the process to create the habitat conservation plan failed, a federal judge or the state Legislature could have decided how the aquifer, which supplies water to the region's 2 million people, should be managed.
In a bit of poetic justice — or perhaps irony — the EAA's vote came 38 years to the day that Richard Nixon signed the Endangered Species Act into law.
The process was guided by Robert Gulley, a program manager with the Texas A&M Institute of Renewable Natural Resources. Before that, he served as a senior trial attorney for natural resource issues at the U.S. Justice Department.
“This is a historic moment,” Gulley said after the vote. “This is the beginning of the final chapter in the dispute over the use of the Edwards Aquifer.”
The plan calls for habitat restoration at the springs, storing water in an underground reservoir built by SAWS, and for all municipal and industrial pumpers to pay farmers not to pump during droughts.
The next step, Gulley said, will be to implement the plan.
First it must be approved by the U.S. Fish and Wildlife Service, which will include public input as part of its vetting process. Once approved, the plan goes into effect Jan. 1, 2013.
The funding part of the plan does not include the contentious rebates.
Instead, the EAA approved alternative accommodations to the entities that benefitted from the rebates. For New Braunfels Utilities, that will come in the form of a conservation grant to help pay for its restoration project at Landa Lake, which will improve water quality there.
San Marcos and Texas State University, which also benefitted from the rebate, instead will lease water to the EAA for a period of time, which will go to SAWS aquifer storage and recovery facility.
The details of those plans will be hashed out in future meetings. Representatives from New Braunfels and San Marcos expressed satisfaction with the compromise, and the overall plan.
“Over the past four years, a lot of people did an awful lot of work that will help protect the region's water supply,” New Braunfels City Manager Mike Morrison said.
The EAA also voted Wednesday to ease into the new fees to fund the conservation plan, charging pumpers 75 percent of the total increase during 2012, or $37 per acre-foot. That's on top of the $47 per acre-foot increase pumpers will pay the EAA for its regular work.
The agency will hold public hearings on the proposed increase in the coming weeks.
That fee is passed directly on to SAWS customers as a line item on their bill.
Depending on the final amount of the EAA increase, monthly bills for average SAWS residential customers — just under 8,000 gallons a month — could go up by about $1.87, bringing the fee to $3.21. Those that use more water will see a bigger increase. The higher fees likely will go into effect this spring.
That's separate from the 7.9 percent rate increase approved by the City Council last month, much of which will pay for repair and cleaning of the utility's aging wastewater pipes.
Staff Writer Colin McDonald contributed to this report.


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Gilles Mettetal, EBRD Director for Agribusiness, speaks about the newly launched Private Sector For Food Security Initiative which will be implemented under the EBRD-United Nations Food and Agricultural Organization framework for food security "We simply don’t have enough food for the future of our world,” says Gilles Mettetal, EBRD Director for Agribusiness.
His warning comes after the dramatic price increases during the food crisis in 2007-08 and a recent second hike, which signal a future of severe food price fluctuations. Demand for food and agricultural products is ever increasing. Global food stocks are at alarmingly low levels and critical natural resources for food production, such as water, are in jeopardy, not least due to climate change which has increased the unpredictability of food supply. Despite these enormous challenges, the solutions seem simple. According to a new initiative developed jointly by EBRD economists and the Agribusiness team called the Private Sector for Food Security Initiative, existing programmes to tackle the food crisis have put too much emphasis on the demand side and have not paid enough attention to structural support problems. In their view, stimulating more private sector involvement would greatly improve productivity and having better-matching exporting and importing countries would help decrease food losses.
The Private Sector for Food Security Initiative also aims to bring together the Bank’s existing countries of operations and its potential new region in the southern and eastern Mediterranean (SEMED) by aiming to match the huge potential for exports in the former area with the massive import needs of the latter, which is the biggest importer of cereals in the world. “Some of our countries of operations like Russia, Ukraine and Kazakhstan are becoming increasingly important global players with the potential to contribute to rising global food demand,” says Mr Mettetal. “If these countries were to fulfil their potential they could supply almost half of the world’s grain export needs!”
Clearly, no single institution has the capacity to achieve this on its own. The initiative therefore aims to improve international coordination. In particular, it strives to better utilise the collective strength of the Multilateral Development Banks’ (MDB) Working Group on Food and Water Security, through joint projects for strengthening social safety nets, addressing food market volatility, increasing investments in agriculture and improving access to water.
The Bank will also utilise the new programme to scale up collaboration in the EBRD-United Nations Food and Agricultural Organization (FAO) framework for food security and specifically the expansion of the EastAgri network of international financial institutions (IFIs) and banks investing in agribusiness to the SEMED region.
Gilles Mettetal tells us more about the initiative in his interview
For more information, please see:http://www.ebrd.com/pages/news/features/food_crisis_initiative.shtml

domain: agronomy


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Hotels in South Kingstown start at $101 per night. Prices and availability subject to change. Additional terms may apply.
Are you planning on traveling to South County and hoping to reserve hotels in the South Kingstown area? You will find 7 lodgings located within 6-mile (10-kilometer) of the center of town.
Travelers searching for a room near the business center of South Kingstown will feel at home at Holiday Inn South Kingstown (Newport Area).
You should investigate the The Vanderbilt Grace as well as the The Chanler at Cliff Walk. The The Vanderbilt Grace is just 7 miles (12 kilometers) away from the city center of South Kingstown. The The Chanler at Cliff Walk, is 8 miles (13 kilometers) away. Alternatively, you may wish to investigate the Point Pleasant Inn & Resort or the Forty 1 North.
Westerly is 20 miles (33 kilometers) southwest of South Kingstown and is home to Wilcox Park and The Flying Horse Carousel. A few Travelocity-listed Westerly places to stay include the Aquastar Inn and Sand Dollar Inn. For another option, stay in Narragansett, 7 miles (11 kilometers) south of South Kingstown, where you can choose between the Lighthouse Inn of Galilee and Atlantic House. While visiting Narragansett, a couple of places to add to your itinerary are the Narragansett Beach and Scarborough Beach.
Prior to leaving South County, why not make sure you are able to watch some local sport. Make your way to Fenway Park, located to the north of South Kingstown. Enlightened travelers that are hoping to find hotels close to the action can choose from the Mandarin Oriental Boston or the Four Seasons Hotel Boston.
Situated 16 miles (26 kilometers) outside South Kingstown's downtown area is T.F. Green Airport. Stay nearby at Crowne Plaza Providence-Warwick Airport or Residence Inn By Marriott Providence Warwick.
At Travelocity, you’ll find really nice hotels in South Kingstown at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location—maybe stay at a hotel near South Kingstown rather than in South Kingstown—we may find you even better rates, too.
Simple! On Travelocity, look through the fantastic offers we’ve already found in South Kingstown then use our filters to find a great deal that’s perfect for you. Enter your travel dates, select the number of rooms you need, and we’ll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
The cheapest hotel in South Kingstown is $101 per night, and we have hotels to suit every budget and every taste. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel’s location. Prices and availability are subject to change. Additional terms may apply.
There are 340 hotels in South Kingstown on Travelocity. Out of reviews, the average rating for South Kingstown hotels is 0.0.
South Kingstown has so many great hotels to choose from at Travelocity—and it’s so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in South Kingstown for you!.
If you want the joy of a fun-filled trip in peak season, visit South Kingstown during . If you’d prefer the peace of off-season, book a stay during quieter months, such as .
Our data shows is usually the cheapest month to visit South Kingstown. However, we have incredible deals all year round, so we’re confident you’ll find a room in your budget whenever you choose to travel.
There are multiple hotels in South Kingstown that will please the whole family. You need adjoining rooms, baby-sitting services or a swimming pool? We got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to South Kingstown. We have plenty of kids-friendly hotels in South Kingstown to choose from on Travelocity!
Because we have at the top hotels in South Kingstown! We want to help you travel more and worry less. That’s why we’ve put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you’re getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.


Police look for witnesses in fatal bike crash
Staff photo by David Paterson
Police investigate the scene of a collision where a cyclist was struck and killed Friday night.
A 74-year-old Mississauga man has died after being struck while riding his bicycle in Cooksville on Friday night.
Peel Regional Police said the man was riding his bike on Hurontario St., near King St., around 8:23 p.m. when he tried to cross Hurontario St. and was struck by a Toyota Camry.
The man suffered critical injuries and was taken to hospital, where he died. The driver of the Toyota wasn't injured.
The Major Collision Bureau is investigating and police are appealing to anyone who may have witnessed the collision to call 905-453-2121 ext. 3710. Anonymous tips can be left by calling Peel Crime Stoppers at 1-800-222-8477.


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Happy New Year, and we hope 2022 will be an outstanding year for you and your pet. But, it’s up to you to keep your pet’s New Year Resolution — great health — which starts with your pet’s annual wellness exam. Also, below we would like to share the current COVID protocol ensuring safety for everyone who brings silver puppies.
The Physical Exam
The annual exam is among the most important tools to keep your pet healthy. As our pets cannot tell us when they don’t feel well, a good veterinarian can identify health concerns early — shortening the road to recovery.
During a physical exam, we will conduct a thorough head-to-toe review of your pet — starting at the head working our way to the tail. We’ll check your pet’s eyes for cataracts and glaucoma, the ears for infection or parasites, the mouth for broken teeth or gingivitis, and the neck for your pet’s lymph nodes and thyroid gland.
Moving down, we will carefully listen to your pet’s chest for a heart murmur or irregular beat — which are signs of heart disease. We also listen to the lungs, feel the abdomen for irregularities, feel the skin and coat condition, check the hips and elbows for swollen or painful joints, and examine the hind-end for hernias, abnormal growths, or anal gland problems.
Finally, we will watch your pet move around the room looking for any signs of pain or neurological issues.
You’ll notice that we weigh your pet upon every visit. Keeping a close eye on your pet’s weight helps us to identify any activity concerns, potential diet adjustments, and any possible underlying health conditions — such as diabetes.
Each year we will review your pet’s vaccination record and recommend any vaccines or boosters based upon your pet’s activities, the climate, and any diseases present in the area. Vaccines are important as they prevent potentially fatal diseases, and every pet needs “core vaccines” including rabies.
A dental exam should be conducted yearly with periodic dental cleaning based upon the results of the exam. Good dental hygiene is vital as bacteria in the mouth, particularly between the teeth and gums, can stress other organs of the body via infections. And, of course, dental disease can be painful for your pet.
Fleas can be more than a nuisance to pets, and heartworm can be fatal. Furthermore, parasites such as roundworm and ringworm can affect humans as well. We typically recommend a fecal sample to check for parasites in the intestine, and a blood sample to look for heartworm. Either topical or internal medicine is an invaluable element to keep your pet healthy.
Based on a pet’s breed and age, we might recommend additional targeted diagnostic testing. Additional blood work, for example, will check for items that can’t be detected during a physical exam such as signs of diabetes, an underlying infection, or poor kidney health. Detecting and treating disease at its earliest stage is best for the pet and less costly to the pet owner in the long run. Of course, owners always have the ultimate say in a pet’s care. But a collaborative approach is often best for your pet’s health and longevity.

domain: pet


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Moody’s Analytics and Sia Partners Announce Collaboration as Part of Moody’s Analytics PartnerAlliance Program
Moody’s Analytics, a leading global provider of risk management solutions, and Sia Partners,a leading management consultancy firm, today announced their new strategic collaboration as part of the recently launched Moody’s Analytics PartnerAlliance program. The partnership involves building a center of expertise at Sia Partners to help the firm implement Moody’s Analytics solutions.
Sia Partners employs more than 900 consultants globally and is joining the PartnerAlliance program as an Elite partner. This status recognizes the company’s extensive experience in implementing Moody’s Analytics banking and insurance software and supporting shared clients over a number of years.
“Sia Partners consistently adds value to the financial institutions it assists,” said Steve Tulenko, Executive Director, Enterprise Risk Solutions at Moody’s Analytics. “With a deep understanding of regulatory, financial, and risk management issues, and a global footprint, Sia Partners is a trusted implementation partner capable of providing trusted delivery options for our expanding client base.”
Matthieu Courtecuisse, CEO of Sia Partners, explained the firm’s rationale for joining the program. “Our experience working with Moody’s Analytics has been excellent. Its strategic platform approach brings a valuable proposition to our customers, while Sia Partners brings relevant expertise in areas such as Basel, FRTB, Anacredit, and IFRS regulations that are of strategic concern to many Moody’s Analytics clients. By increasing our level of expertise around Moody’s Analytics solutions, we can better help our shared clients fully realize the benefits of deploying those solutions.”
The alliance is non-exclusive and both companies remain independent to collaborate with other parties in the best interest of clients.
About Sia Partners
Sia Partners is a global management consultancy firm composed of passionate consultants with a mission to help clients to drive and achieve business change. Through unparalleled industry expertise, the firm delivers superior value and tangible results for clients. Created in 1999, the firm is headquartered in Paris, France, and employs more than 900 consultants across 20 offices. Sia Partners is organized as a partnership, it generated €155M in 2016. The firm has doubled in size over the last three years and is ranked #21 in the Vault Top 25 Consulting Europe ranking. Further information is available at www.sia-partners.com .
About Moody’s Analytics
Moody’s Analytics helps capital markets and risk management professionals worldwide respond to an evolving marketplace with confidence. The company offers unique tools and best practices for measuring and managing risk through expertise and experience in credit analysis, economic research, and financial risk management. By providing leading-edge software, advisory services, and research, including the proprietary analysis of Moody’s Investors Service, Moody’s Analytics integrates and customizes its offerings to address specific business challenges. Moody's Analytics is a subsidiary of Moody's Corporation (NYSE:MCO), which reported revenue of $3.6 billion in 2016, employs approximately 10,600 people worldwide and maintains a presence in 36 countries. Further information is available at moodysanalytics.com .
ISABELLE CORNELIS, 0044.207.772.5207
Assistant Vice-President, Corporate Communications
KATERINA SOUMILOVA, 001.212.553.1177
Assistant Vice-President, Corporate Communications
HECTOR LIM, 0061.292.708.141
Vice President, Corporate Communications
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IoT-based indoor location intelligence platform for Smart Buildings InnerSpace has been awarded a patent by the US Patent Office for its approach to generating maps for indoor navigation. The patent (#10458798B2) titled “Method for Sensing Interior Spaces to Auto-Generate a Navigational Map” protects the company’s unique approach leveraging LiDAR to create maps of indoor spaces.
“The Indoor location market is poised for dramatic growth as public and private sectors recognise its value to operations, safety and revenue,” said InnerSpace CEO James Wu. “We have systematically eliminated the barriers to implementation and scale to ensure indoor location can reach its potential. One of the ways we have done this is to tackle the need for on-demand floor plan creation to keep maps up to date as building interiors change.”
InnerSpace claims to be the most accurate indoor location platform available on the market today. It uses WiFi networks and/or its proprietary sensors to measure how people and things behave within an indoor space. The company says it makes it easy for clients in food & beverage retail, public safety and security, workplace experience, and real estate operations to turn any building Smart. Clients use the InnerSpace platform, which includes analytics, mobile apps, out-of-the-box integrations and API access, to drive meaningful improvements to operations and revenue.
The patent awarded pertains to the InnerSpace Mapping Sensor that leverages LiDAR scanning capabilities to measure distances within an indoor space and create a local point cloud model of the environment that is converted to a 2D floor plan or map.
“One of the biggest impediments to adoption of indoor location has been the manual effort required to create maps, and keep them updated as buildings change,” Mr Wu said. “Leveraging InnerSpace ensures that our clients can reconfigure their spaces at any time and see those changes reflected in their maps, applications and analytics.”


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Source: M. CLOITRE/CNRS-ATOFINA
Have you ever wondered why it is that your toothpaste flows like a liquid when you squeeze the tube hard but pulls back like stretched elastic if you squeeze too gently? Scientists from France now have a partial answer: they have found in a series of experiments that pastes behave mechanically much like glass. The insight, reported in this week's issue of Physical Review Letters, may help researchers develop better versions of industrial pastes, such as the additives commonly used in inks. These pastes let the ink flow through printers but stay put on, say, patterned fabrics, like the polka-dot cloth at right. Moreover, this knowledge may shed more light on the physics of glass and other so-called disordered systems in general.
Michel Cloitre and his colleagues at the joint laboratory of the National Center for Scientific Research (CNRS) and the company ATOFINA in Levallois-Perret, France, tested a paste of tightly packed 200-nanometer-diameter gel particles in a concentrated solution. They placed a thin sample between two plates and applied a twisting force large enough to make the sample flow to the upper plate. Then they removed the stress and watched how the material recovered. Almost immediately, the paste began to spring back, although slowly, and continued to do so for hours on end. This slow recovery is, in fact, typical of glasses. The team also noted that the sample "aged" in that it grew increasingly stiff with time during recovery--another common trait of glass materials. The scientists suggest that the particles are distorted under high stress, and swell and jostle for position upon relaxation, again trying to reach equilibrium. It is because the relief of one particle may come at another's expense, they say, that the process is so slow.

domain: chemistry