Sweeney. B.W., and D.H. Funk. 1987. Aquatic Insects 13:1–11.
The genetic structure of Dolania populations in South Carolina, Alabama, and Florida was examined using starch gel electrophoresis. All study populations except Alabama consisted entirely of D. americanaEdmunds and Traver. Electrophoresis revealed that the Alabama site contained both D. americana and an undescribed species (D. sp. nov.), with the latter taxon predominating. Individuals of the two taxa had nearly fixed allelic differences at two loci (Est 4 and Gda). The extent of genetic differentiation between populations of the two taxa in the same river or between adjacent river systems was significantly greater than between D. americana populations separated by large geographic distances. Populations of both species were characterized by relatively normal levels of polymorphic loci (average = 23%) but unusually low levels of heterozygosity (average = 0.03). Genetic variation between the Florida and South Carolina populations of D. americana was statistically significant. There was also some indication of slight genetic differentiation among populations of D. americana within the Blackwater River in Florida. No significant genetic variation was observed between cohorts of D. americana at a given site.


text:
Agriculture universities are educational institutions that specialize in the study of agriculture and related sciences. They provide courses in various branches of agricultural sciences such as agronomy, horticulture, forestry, and crop science as well as related disciplines like plant and animal genetics, agribusiness, and food science. There are many countries across the globe that have established universities specifically dedicated to the field of agriculture.
The United States has both public and private universities that specialize in this field. Famous universities like the University of California-Davis, Michigan State University, the University of Florida, and Texas A&M University are some of the most renowned public institutions in the country that offer robust programs in agricultural studies. Other states like Illinois, Pennsylvania, New York, and Ohio also offer accredited institutions dedicated to the study of agriculture.
In Europe, some of the most popular agricultural universities are the University at Wageningen, the Swedish University of Agricultural Sciences, the University of Hohenhelm, and the University of Agricultural Sciences in Vienna. Countries like France, Germany, Italy, Spain, England, and Poland also offer high-quality institutions dedicated to the education of students in the field of agriculture.
In Asia, renowned universities like the Chinese Academy of Agricultural Sciences, the National Taiwan University of Science and Technology, India’s Central Agriculture University, and the National University of Singapore are amongst the leading academic institutions for the study of agriculture. Other countries like South Korea, Indonesia, Thailand, and Japan have established top-tier universities dedicated to the advancement of the field.
Agriculture universities are not limited to developed countries, as there are quite a few in the African continent. For instance, the University of Pretoria in South Africa operates multiple campuses across the country and offers numerous degree programs in the field of agriculture. Other countries like Zimbabwe, Morocco, Kenya, Ghana, and Nigeria also have well-known universities that provide courses in agriculture.
Agricultural Degrees and Programs
Agricultural universities offer degree programs at the associate, bachelor, master, and doctoral levels, with specialized degrees and certificates also available. The course curriculum usually covers aspects like plant biology, plant production, pest control and management, soil science, animal science, nutrition, agricultural engineering, and agricultural business.
Furthermore, students enrolled in a degree program at the agricultural university have the opportunity to pursue practical experience and gain hands-on skills for the career in the field. In addition to classroom studies, each student is expected to fulfill the internship requirements in order to gain work experience and develop industry contacts. This enables them to hone their skills and become professionally competent.
An agricultural degree program also cultivates critical thinking, problem solving, and communication skills in the students, preparing them to tackle any professional challenge with ease. Moreover, studying at a reputable agricultural university also enhances the career prospects of the individual. Many of the employers in the field prefer to hire individuals who have completed their education from a university of good standing.
In addition to the academic courses, some of the agricultural universities also offer a range of extracurricular activities that students can participate in. From playing sports to joining student-run clubs to taking up a leadership role in student government, there are an array of activities available to the students that cultivate their personal growth while providing an enriching college experience.
Additional Benefits of Studying at an Agricultural University
Agricultural universities offer numerous student-centric measures, such as career advising, guidance on professional job placements, and access to internships and research opportunities. These measures help build the student’s professional skills, enabling them to secure employment after they complete their studies. Furthermore, they also provide excellent financial aid programs, and some programs even offer scholarships.
Many agricultural universities also have established alumni associations that cater to their graduates, allowing them to maintain close ties with their alma mater and help the institution grow. These associations also bring together alumni from across the globe to take part in networking activities, mentor and support new students, discuss industry trends, and find job and career opportunities.
Overall, agricultural universities offer students a comprehensive academic experience and enriching opportunities, preparing them for a successful professional career. With the advancements in technology and new approaches to farming, agricultural universities have become an invaluable resource for the modern agricultural industry.
Research and Professional Development
Agricultural universities also serve as a platform for research and development, providing a number of research facilities and equipment required to undertake state-of-the-art projects. Students enrolled at these institutions can avail of mentorship programs, innovation centers, and access to advanced scientific and computer laboratories.
In addition to academic projects, the research and development initiatives carried out at the agricultural universities often translate into market-ready products. This is beneficial to the industry, as it helps in the diffusion of innovations and technologies into the sector. Moreover, it also helps to introduce new products and services to the market, further enhancing the potential growth of the agricultural industry.
Many of the research initiatives at the agricultural universities are funded by private organizations, research institutes, and government initiatives. In many countries, financial support from these sources enables students to carry out their projects without additional cost and in some cases, earn additional stipends. This kind of funding enables the students to focus solely on their research, enabling them to pursue their academic interests and professional pursuits in a proactive academic environment.
Professors associated with the university also benefit from the research activities carried out at the institution. They use the acquired knowledge and data to enhance their own understanding of the field and take part in activities like teaching, consultancy, and advisory roles. Professional recognition gained through such activities further spearheads the development of the agricultural industry.
The presence of an agricultural university not only benefits the students and faculty, but it also augments the strength of the agricultural industry. Having an educational infrastructure dedicated to the growth of the field helps to create a pool of talented professionals who are constantly working towards the betterment of the sector. This ultimately contributes to the overall growth and transformation of the agricultural sector.

domain: agronomy


Watergate era republicans really had their proorities screwed up! They actually seemed to think there was something more important than partisanship,
Don’t mythologize watergate. It took over 2 years from the break-in to nixon’s resignation. And the same partisan divide regarding the seriousness of the problem existed then as does now. There were regular accusations that it was all a liberal conspiracy to either force/trick/blackmail nixon into governing more liberally or to damage the presidency.
What saved us then was not necessarily principled republicans but a democratic majority in both houses of congress.
Because Trump has an unprecedented power to induce schadenfreude-fueled rage boners which are easily converted to clicks, ad impressions, and eventually to people arguing over dumb shit which leads to more clicks and ad impressions when they come back to argue more. C’mon, it’s a cheap fun high, BB makes a nickel, and you’re already reading this right now anyway. Nobody gets hurt. It’s fun. Clicky click click click click.
Alternate answer: Major outlet comments sections are godawful subscription-paywalled warzones. BB is a nice little suburban cul-de-sac away from all the hustle and bustle, where it’d be rude not to chat with the neighbors over a lemonade even if you kinda hate them.
You think Trump is going to resign? Akin to voluntarily Losing? I’d be surprised. Plus it will be so much more fun for the GOP to have to impeach him, for him to put up a fight, for all the indictments to have to come out, for staff, secretaries of various departments, senators and congressmen all have to be carted away in cuffs.
Look at it this way. If he stays president, they can’t prosecute him, not until after he is impeached. If he resigns, they can go after him right away.
If I may turn that question around, why wouldn’t the President asking the head of the FBI not to investigate allegations of Russian influence over the White House be discussed on BoingBoing or anywhere else?
True. And I’m in favor of impeaching Trump. Pence is at least a more predictable brand of evil. But the most important factor in either course is taking the Senate and hopefully the House away from the GOP.
Careful when you speak truths like that, it cuts both ways. Obama was very into ferreting out leaks to the press, and I’ve been very impressed recently with how little my fellow Liberals actually value freedom of expression.
There are only about a million other places on the Internet to do that already.
I miss the days of BB truly being a Directory of Wonderful Things (which is what it started out as, and was for a long time). It was a truly unique and special place on the web, made by, and for, Happy Mutants.
Now it’s mostly a Directory of Monetized Clickbait. I don’t get the sense any of the BB crew is really passionate about it anymore. Sad.


KD All in One Solar Street Light With CCTV Camera 1.High quality Aluminum alloy lamp case,beautiful, durable and Corrosion resistant 2.Four different lighting mode for different purpose and application
The SSL-A2 All in one Solar Street Light contains a mono solar panel, led lamp, lithium battery and controller. Solar street lights are easy to install and come with Passive Infrared Sensor (PIR motion sensor) to adjust the LED light brightness intelligently
80w high-quality ip66 integrated led solar street lighting system - street lighting solar manufacturer reviews and products contains high-efficiency monocrystalline silicon with a maximum power of 18v 100w. it can produce ultra-bright light for a long period due to its strong lithium battery with a discharge time of up to 40 hours on power-saving mode and 20 hours on full
Make sure this fits by entering your model number.; ☀【All-In-One Design】Dailyart solar street light adopts all-in-one design. The top solar energy panel can absorb solar energy and convert it into electricity, thereby helping you save electricity costs. 468 high-brightness LEDs, 328 more LED beads than other 120W street lights.
This series of all-in-one solar light is easy to install on the lamp pole and looks very great either on main streets on country roads. Our special design is to put the battery box out of the lamp body, which is very convenient for after-sale maintenance after several years if any need.
The SSL-A1 series "All in one” solar street light is an all new kind of solar street light for road lighting. It combines a highly efficient solar panel which is connected to a high capacity LifePO4 battery that powers the microwave sensor and LED light source. ... Online. Free …
hardoll butterfly humming bird dragon fly 6 led decorative solar light and 200/300/450w light 45000lm led solar street light pir. features: utilizes solar energy to charge the 1. 2v/300mah built an aatype rechargeable batteries; the led lamp colors change from red, green, to blue; comes on a beautiful transparent stake with 5 cool white leds
Solar Street Light, Outdoor Street Light, Street Lighting manufacturer / supplier in China, offering All in One Solar Street Light40W 60W 80W 100W Integrated Solar Street Light, Highway Square Village LED Solar Street Light Outdoor Lighting, CE RoHS 30W 60W 80 90W 100W 120W 150 Watt Wind Solar LED Street Outdoor Lighting and so on.
The integrated solar street light is an intelligent outdoor lighting system that integrates the best energy saving parts---solar panel, led lamp ,sensor, controller and lithium battery all in one box. During the day the highly efficient solar panel collects energy from the …
Qatar Low price ip65 solar panel radar sensor 30w 60w 90w 120w 150w all in one led solar street lamp. Inquire. Qatar High quality die cast aluminum ip66 waterproof garden road 60 120 180 watt all in one led solar street light. Inquire.
solar street lighting | suka solar ghana - efficient. suka commercial grade 2 pack solar lights outdoor, wdtpro super bright motion provide a great solution for streets, roadways and highways. suka solar's led street lights are combined by led street light, solar panel, controller, battery, and pole. solar systems are perfect for street lighting - they can provide
China all in one solar street light catalog of ABS IP65 Waterproof Radar Sensor Solar Street Light LED Lamp 120W with Remote Control, LED Solar Street Light IP65 Waterproof Outdoor Lighting 200W Solar Lamp provided by China manufacturer - Zhongshan Haoxintai Lighting Technology Co., …
All In One 20W to 120W Solar Street Light BD-X series BD-X solar street light is with patent design to make installation and maintaining more economical, and flexible configuration to assist client to meet different projects' requirements.
Jan 04, 2019· These panels are mounted on the lighting structure or connected in the pole. PV panels have a rechargeable battery, providing power to the fluorescent or LED lamp during the entire night. Get solar Street lights installed by us , just by dialing our digits.
Waaree All in One Solar Street light 500 Lumens WEPSWS605 All in One integrated street light. Max 500 Lumens. With in built PIR motion Sensors. Auto Dusk …
An All-in-one solar street light LED lamp can provide up to 200 lumen/watt lighting efficiency. You can save almost 80% of energy as compared with traditional street lights. And since solar street lights are also off-grid, it leads to zero cost for operation and electricity bills are eliminated. 4.
ALL IN ONE Solar Street Light I NTEGRITY . HIGH BRIGHTNESS . EASY-INSTALL ALL-IN-ONE SOLAR LIGHT SERIES INTRODUCTION: 6W-120W All in one integrated solar garden and street light for public square, plaza, courtyard, garden, park, street, …
Solar Illuminations presents this unique all-in-one solar LED street light. Choose from five different models with LED power options from 5W to 40W and an output of 550lm to 5,200lm. Prices from $399.99.This all in one solar powered street light is supplied complete and ready for quick and easy
All-in-one Solar LED Street Lamp Light Outdoor IP65 for Street SF-SYT308A. ALL IN ONE SOLAR STREET LIGHT SF-SYT309. ALL IN ONE SOLAR STREET LIGHT SF-SYT218. ALL IN ONE STREET LIHGT SF-SYT219. Waterproof Solar Powered Garden LED Street Light SF-SFT202.
Our expertise and our latest Solar Street Light technology are based on the experience of many years in the production of Solar LED Street Light, all in one integrated solar street light. Suneco provides Solar LED Street Light, all in one solar street lighting Solutions to …
Solar Street Light, Solar Light, Integrated Solar Street Light manufacturer / supplier in China, offering 100W All-in-One Integrated Solar Street Light with Iot & CCTV Camera, Esavior 15W All in One Solar Street Garden Park Parking Lot Wall Square Light Lighting Lamp, 60W All in One Solar Street Light Solar Road Highway Light and so on.
if you are looking for high quality lithium ion & lifepo4 battery solution,come to us. solar energy storage batteries. battery for solar system, solar street light,save more energy and cycel life as long as 5-7 years. industrial batteries. 12v 30ah solar home lighting systems in bhilwara, rajasthan lifepo4 battery.
LED Solar Street Light, Solar Garden Light, IP67 Solar Street Light manufacturer / supplier in China, offering Maintenance Free 180W Integrated All in One LED Solar Lighting Solar Street Light for Road Outdoor Garden, 16 Inch Energy Saving Rechargeable Solar DC Standing Fan, Cm3024z 12/24V 30A Dual USB Solar Charge Controller and so on.
Solar Street Light, All in One Solar Street Lamp, Integrated Solar Street Light manufacturer / supplier in China, offering Free Sample All in One Integrated Solar LED Street Light, 200W 150W 100W Powered Motion Sensor Outdoor Waterproof System Wall Solar LED Street Lights, Cheap 100 LED Waterproof Motion Sensor Kit Solar Street Light Outdoor for Wall and so on.
Home solar led all in one street lamp Off Grid Inverter 2.5kva 12v Pure Sine Wave Felicitysolar off grid solar charger inverters, cover power 2500va 3500va 5000va with DC24/48 voltage adaptable.
8m 45w 220v output voltage double arm solar street light shenzhen sunway led light co.ltd is a power seller in dhgate.we are a professional supplier of all kinds led lights .. super bright commercial 250w solar street light motion outdoor 30w 60w 90w solar flood add to cart. 2019 new aluminum alloy double sided luminous solar light 10 5. us $47.06 56.32 / piece; add to
This 90W all in one solar street light system can provide 6500k daylight white as it equipped with 84pcs high quality LED beads and 12.8V/48Ah battery which life up to 50,000 hours.It provides higher lumens with lower energy consumption.Malaysiaellent as an area light, parking lot light, patio light or yard light. Main Features: All-In-One Integrated Design
Buy from our wide collection of energy efficient LEDs, solar street lights and solar flood light kits, etc. in Nigeria from Wavetra Energy store online and offline Buy LED, Solar street light and accessories in Nigeria. Why buy from Wavetra Energy LTD? At Wavetra Energy, we …
outdoor pathway yard stainless steel led a-zone l10 solar motion sensor light outdoor - amazon, ip65 waterproof solar power featured product. fob price: us $ 0.4 / piece 30w 50w 60w 80w 100w tuv ce iso certificate outdoor solar street road garden led light specification (more) solar panel workshop foreign affairs
cheap solar lamps, buy quality lights & lighting directly from china suppliers:solar lamp garden solar bulb light e27 edison bulb for street tree lighting supercapacitor solar street light untuk landscape with 9.8meter cord enjoy free shipping worldwide! limited time sale easy return.


4262 Glordano Avenue
Commute to Downtown North Port
Almost all errands require a car.
It is possible to get on a bus.
4262 Glordano Avenue has a Walk Score of 0 out of 100. This location is a Car-Dependent neighborhood so almost all errands require a car.
This location is in North Port.
Explore how far you can travel by car, bus, bike and foot from 4262 Glordano Avenue.
09 VENICE/US 41/NORTH PORT
1713 DOWNTOWN/US 41/NORTH PORT SUNDAY
100 AIRPORT/DOWNTOWN/I-75/NORTH PORT
80 NORTH PORT KNIGHTS TRAIL
28 S BISCAYNE/TOLEDO BLADE
90 AIRPORT/DOWNTOWN/VENICE/NORTH PORT
View all North Port apartments on a map.
This location is in the city of North Port, FL. North Port has an average Walk Score of 7 and has 57,357 residents.Learn More About North Port


The system, called T24, is expected to integrate eight other separate systems that the bank uses currently.
Some of the systems are used in agency banking while others run its mobile banking service, but these will now be integrated under the new banking platform.
"We are acquiring the system which should come with software and hardware that will help cut operational costs and improve the way we deliver our services to customers," said
KCB's cost-to-income ratio (CIR) at the end of March stood at 49 per cent, down from 51 per cent last December and 64 per
"Cost containment is one area we can say we have managed to deal with ahead of schedule. It was a herculean task because two years ago it stood at 64 per cent," said
READ: KCB seeks to grow customer numbers by two million
The KCB chief executive said he sees possibility of increased convergence between the telecoms and banking sectors. KCB, which already offers mobile banking products under the M-Benki platform, has plans to put more services on the mobile phone.
"What we are seeing is convergence between the mobile and banking businesses. We are looking at technology as a way of delivering and increasing the number of our products and services," said
The intended launch next month of
Most Popular Stories
- Shia LaBeouf Plea Deal, Alcoholism Treatment
- Ohio State Band Chief Fired After Probe
- Stop-Start Engines Save Gas, Reduce Emissions
- Hispanic Leader Goes the Extra Mile
- Ukraine Says Russians Firing Across the Border
- Jennifer Lopez, Pitbull to Perform at Fashion Rocks
- Ricky Martin Joins 'The Voice ... Mexico'
- Ford Q2 Net Profit up 6 Percent
- U.S. Weighs Refugee Status for Immigrant Kids
- Morgan Stanley Ponies Up $275 Million to Settle SEC Charges


text:
The Singing reality show, Indian Idol 12 turned to be a successful venture despite being mired with numerous controversies. Even the contestants of the show found a huge fan following for themselves. Moreover, there were plenty of music composers, singers, and even filmmakers who have made deals with the contestants to collaborate with them in some projects in the future. Speaking of which, Shanmukhpriya who has always been on the receiving end of criticism has bagged a project already, well, with none other than Arjun Reddy star Vijay Deverakonda.
Vijay Devarkonda Fulfills his Promise as he Collaborates With Indian Idol Contestant Shanmukhpriya for Liger
If one may recall, in one of the episodes of the show, Vijay Promised that he will be collaborating with Shanmukhpriya for his upcoming film. Devarkonda took to his Instagram account dropped a video, captioning, ” “Welcome @shanmukhapriya_1925 on board #Liger There is no greater happiness than being able to make someone’s dream come to true 🙂 Team #Liger welcomes this little Rockstar SMP onboard our terrific album!”
View this post on Instagram

domain: entertainment


text:
Snyder appoints Walsh, Redford to key roles
LANSING — State Rep. John Walsh, who helped shepherd the state’s “grand bargain” through the Legislature to help settle Detroit’s historic bankruptcy, has been named the director of strategy for Gov. Rick Snyder.
Snyder also appointed Kent County Circuit Judge James Robert Redford, who lost a bid for state Supreme Court in November, as his chief legal counsel.
Walsh, a Livonia Republican, is seen as a legislator who could lead in a bipartisan fashion and he proved himself as chairman of a special committee dealing with the state’s contribution toward solving the city’s bankruptcy. He helped craft the grand bargain that both sides of the aisle could live with in the House of Representatives and Senate.
The bargain sent $195 million to Detroit to help cushion the blow for retirees who were seeing a cut to their pensions, as well as protecting the masterpieces at the Detroit Institute of Arts from being sold in a bankruptcy proceeding.
Walsh was first elected to the House of Representatives in 2008 and couldn’t run again because of term limits. He will replace Bill Rustem, who retired earlier this year.
“It’s essential to have such talented individuals who have a passion for helping the people of our state and the vision and expertise to craft policy and build relationships that will help us accelerate our state’s dramatic comeback and work to keep moving Michigan forward,” Snyder said in a statement. “I know I’ve found the right people in Rep. Walsh and Judge Redford.”
Redford has served as a Kent County judge since 2003 and was nominated at the state Republican Party’s convention in August as a candidate for a Supreme Court slot. He also has nearly three decades of service in the U.S. Navy, working for the Judge Advocate General Corps and as a military trial judge. He finished third in the race for two Supreme Court slots behind Richard Bernstein and Supreme Court Justice Brian Zahra.
Redford replaces Mike Gadola, who Snyder appointed to the Michigan Court of Appeals, last month.
Both will start their new jobs in January.

domain: politics


text:
It's incredible where graffiti shows up, isn't it?
So someone took a hike and spray painted the rocks. Incredible. The beauty of the rocks show through though.
He broke his stride for me He threw me a rope I threw a rock at his head He was generous It was his nature I pushe...

domain: artistic


text:
If you want to perk up, quickly soak up the Saiyan Rage that is concentrated in this splendid Dragon Ball GT Wall Art Canvas!
- Material : cotton and linen li>
- Extremely accurate color rendering
- Appearance : “painting canvas”, free of reflections
- Ultra Light : a nail is enough to hang it on the wall
- “Canvas” printing : superior print quality in oil
- Models: avec or without wooden frames (canvases only) span>
- STANDARD DELIVERY AVAILABLE
Refer to our SIZE GUIDE if you are not sure which Size to Order.


text:
DREAMERmarks the return of the Parisian De La Romance.
Vincent Girault’s, producer and multi-instrumentalist, music is a candid bubble, a preserve territory, almost virginal, where you cross, mane in the wind, the world of childhood and of wide spaces. Organic instruments and sustained tempos embark upon with poetry and sensuality, like a natural bridge between pop and experimentations.
De La Romance first touched the audience in 2015, with the release of a maxi vinyl, gathering his 2 Eps AS WE FEEL & SECRET WORLD, in which Vincent Girault spread out an electronic pop in zero gravity, supported by multiples cinematic videos.
DREAMER underlines this aerial Technicolor direction with even more freedom. This single recorded in the UFO studio whispers to our numbed souls, that now, is the time to live our dreams.
DREAMER announce the DREAMERS album to be released in springtime.


text:
Athabasca Oil is looking for a joint-venture partner to help develop its land in Alberta's Duvernay shale region this year, CEO Sveinung Svarte said Wednesday.
The oil company currently has nearly 142,000 hectares of land in the Duvernay, about 81,000 of which is in the "sweet spot" of the region.
Developing the Duvernay has "large capital needs," so taking on a partner would be an "ideal" situation, Svarte said at the TD Securities Calgary Energy Conference.
Athabasca disclosed nearly a year ago that it was in the early stages of forming a joint venture for its Hangingstone and Birch oil sands properties, though no deal has come to fruition yet.
On Wednesday, Svarte said that process was still ongoing.
"We're still working on that and we hope to have something done, and just cannot tell about the timing," he said.
"But there's still parties interested in those joint ventures and we hope to have it done."
In the meantime, Athabasca is moving ahead with the first phase of Hangingstone on its own. In November, its board of directors gave the green light to the $536-million project.
The first 12,000-per-day phase of the steam-driven project is expected to start producing oil in early 2015. Athabasca plans to follow it up with two expansions that will bring daily production up to around 80,000 barrels.
Another Canadian energy company, Talisman Energy Inc., is actively marketing its holdings in the Duvernay as part of a broader plan to trim its portfolio.
John Rossal, Talisman's senior vice-president for Canada, said the company is aiming for an outright sale.
"Our preference in the North Duvernay would probably be a cash disposition, although if the right JV opportunity came along we would certainly seriously consider that," Rossal told the conference.
"I think it's fair to say that the JV market may have cooled somewhat from what we've seen a year, two years ago."
Athabasca's Svarte said the appetite for Duvernay deals is a lot greater than in the oil sands.
"We still see four-five players worldwide looking for oil sands and they're just looking for the right opportunity. There has to be size and quality. We believe it can still be done," he said.
"In Duvernay it's probably a lot different. We probably see five times more players internationally, 20 or 30, looking for positions."
Athabasca is no stranger to joint ventures. In 2009, it sold a 60 per cent interest in its MacKay River and Dover oil sands projects to PetroChina.
Early last year, PetroChina exercised its option to buy Athabasca's 40 per cent stake in MacKay River for $680-million.
The Chinese company will have the opportunity to do the same with Dover later this year. PetroChina can buy Athabasca's Dover stake for $1.32-billion within a month of the project obtaining regulatory approval – something Svarte said he expects to happen later this month or early August.

domain: news


text:
Army Veteran Tattoo Ideas. See more ideas about military tattoos, army tattoos, patriotic tattoos. Web a military tattoo is a great way to show your support for our troops.
Other popular images include eagles, eagle. And a military tattoo is. Web there are many types of military tattoos that you can make use of when it comes to looking extraordinary in your appearance the way people have come to.
Web a military tattoo is a great way to show your support for our troops.
Web veteran tattoo ideas 44 pins 5y p collection by rob similar ideas popular now armor tattoo norse tattoo vietnam vets vietnam war photos disabled veterans benefits. People have used tattoos to honor soldiers and warriors for most of human history. Web the anchor is a classic military tattoo idea, they look great tattooed in any style, and they represent your link to home no matter where you are in the world. Other popular images include eagles, eagle.

domain: design


Tehran, June 16, The Iran project – The idea of a Greater Kurdistan has long been discussed among Kurds and the regional countries. On the one hand, Kurds have always referred to it as their primary goal, and regional countries, on the other hand, have constantly insisted that they are opposed to the idea. It seems that the field is provided for the realization of creating an independent nation state now more than ever.
Kurds are an old ethnic group that even rooted in the Iranian mythology and now are scattered in the West Asia. They are populated in south-eastern Turkey, north-eastern Syria, northern Iraq, and north-western Iran.
Kurds have always dreaamed of a Greater Kurdistan, that is, an independent Kurdish state uniting the Kurds of Turkey, Syria, Iraq and Iran but as it would need to be carved out of four sovereign countries, the idea has always been opposed.
Greater Kurdistan and the Israel’s model
Some analysts’ depiction of a Great Kurdistan resembles Israel in the Palestinian region that was created by invading the countries of Jordan, Syria, Palestine, and Egypt while from the beginning it has engaged in conflicts against neighboring countries and the population of occupied territories.
A few months ago, Israel’s Ambassador to the US Ron Dermer stated that Tel Aviv supports the aspirations of the Kurds for independence, comparing their struggle to that of the Israelis.
Kurdistan’s condition is the same or even worse than the Israel’s. Since Kurds have considered the idea of a Greater Kurdistan, the governments of Iraq and Turkey suppressed them tougher than before. Iraq, under former Iraqi dictator Saddam Hussein brutally suppressed Kurds; they even used chemical weapons to attack the people. Turkey has long been embroiled in a conflict with Kurdish forces within its own borders, and since the collapse of a two-year ceasefire between the Turkish government and the PKK (Kurdistan Workers Party) last July, violent clashes between the two groups have become common so it can be said the idea of a Greater Kurdistan is no way accepted by the regional countries.
US and Kurds, from love to hatred
In line with using various ethnic groups to achieve their interests, Americans have also used Kurds as much as possible.
Turkish President Recep Tayyip Erdogan criticized Washington over its active support of the Kurdish fighting force in Syria. He also said earlier that the United States is creating a “pool of blood” in the region by its support of the Syrian Kurdish Democratic Union Party (PYD) and its military wing, People’s Protection Units (YPG).
Before the Islamic Revolution of Iran, Mohammad Reza Shah Pahlavi, supported by the US, helped Iraqi Kurds but after the 1975 Algiers treaty, he suddenly drew support back of Kurds and paved the way for Saddam Hussein to suppress them.
In the first and second Gulf War, US almost supported Kurds but finally abandoned them and refrained to prevent their bloodshed by Saddam Hussein. Americans also pursued this strategy in Iran-Iraq war and did not react seriously to the chemical bombardment of Halabja.
After the regime change in Iraq, Kurds were once again considered by the US and the Kurdish Regional Government (KRG) was formed since US had plotted to divide Iraq but ISIS attack to the region prevented them from achieving their goal and the idea of a Greater Kurdistan is apparently once again has been put on the agenda.
Why do Americans support Syrian Kurds?
ISIS’s attack to Kurds has made them appear as an oppressed nation in the world’s public opinion. Iran also supported Kurds providing them with weapons and military advisors to defend the Iraqi Kurdish cities.
However, America has recently had a chance to implement the plot of Syria’s division. They try to capture the Syrian land for the Kurds by direct military support including the presence of military forces and strong air support.
America’s largest air base in Syria is being established in the Kurds-controlled regions. Other countries also support Kurds overtly and covertly so that they can assign them an important role in the Syria’s future.
In conclusion, with regard to the history of America’s support for various groups and the serious intention of the regional countries to confront with the creation of a new Israel, It does not seem that Kurds still manages to create an independent state, but in the current situation, the Kurds will have an important role in the future of Syria negotiations which, in fact, strongly depends on the battlefield.


text:
First Trust Enhanced Equity Income Fund (NYSE:FFA) was the recipient of a large decrease in short interest in March. As of March 31st, there was short interest totalling 3,900 shares, a decrease of 54.7% from the March 15th total of 8,600 shares. Based on an average daily trading volume, of 33,600 shares, the days-to-cover ratio is currently 0.1 days.
NYSE FFA traded down $0.04 on Wednesday, reaching $19.44. The stock had a trading volume of 27,090 shares, compared to its average volume of 37,133. First Trust Enhanced Equity Income Fund has a 1-year low of $12.85 and a 1-year high of $19.68. The firm has a fifty day moving average of $18.48 and a two-hundred day moving average of $17.02.
The business also recently announced a quarterly dividend, which was paid on Wednesday, March 31st. Stockholders of record on Tuesday, March 23rd were issued a dividend of $0.315 per share. This is a positive change from First Trust Enhanced Equity Income Fund’s previous quarterly dividend of $0.29. This represents a $1.26 annualized dividend and a dividend yield of 6.48%. The ex-dividend date of this dividend was Monday, March 22nd.
About First Trust Enhanced Equity Income Fund
First Trust Enhanced Equity Income Fund is a closed-ended equity mutual fund launched and managed by First Trust Advisors L.P. The fund is co-managed by Chartwell Investment Partners, L.P. It invests in public equity markets of the United States. The fund seeks to invest in stocks of companies operating across the diversified sectors.
Featured Story: Stop Order Uses For Individual Investors
Receive News & Ratings for First Trust Enhanced Equity Income Fund Daily - Enter your email address below to receive a concise daily summary of the latest news and analysts' ratings for First Trust Enhanced Equity Income Fund and related companies with MarketBeat.com's FREE daily email newsletter.

domain: economics


text:
Swindon Town release Alessandro Cibocchi by mutual consent
Defender Alessandro Cibocchi has had his contract with Swindon Town cancelled by mutual consent.
The 29-year-old signed a two-year deal at the County Ground last summer, but will now return home to Italy for family reasons.
He made a total of 26 appearances for Swindon last season, 12 of them coming as a substitute.
"I would like to thank all the Swindon fans and everyone at the club," he told the club website.
"Also thank you to my team-mates for the past year I have had with the club because they have all made me feel very welcome and helped me.
"I have enjoyed my time with Swindon Town and wish them success this season."


text:
Implementation of the Latest Technologies in Online Casinos
A secure web connection is called for to have a smooth gaming experience as all graphics, sounds, and also animations are filled through the web. Many on-line gambling establishments allow gameplay with an HTML user interface, Https://Www.Rah2050.Ca/Forum/Profile/Kindraleddy7068/ previously this was done via browser plugins, such as Flash Gamer, Shockwave Gamer, sugarxe.com or Java. Download-based Download-based online casino sites require the download of the software program client in order to play and wager on the casino games offered.
Download-based on-line casinos typically run quicker than web-based online casinos considering that the graphics as well as sound programs are cached by the software program customer, instead than having to be packed from the Web. On the other hand, the first download as well as installation of the casino site’s software program take time.
Virtual Reality Casino – How Does it Work and What to Expect?
This software ensures that every deal of the card, the result of a dice throw, or reignersworld.org the results produced by the rotating of a vending machine or roulette wheel is completely random and https://blog.smartdigitalinnovations.Com/community/profile/Barney051622901/ also unforeseeable. PRNGs make use of a set of mathematical directions referred to as a formula to produce a long stream of numbers that offer the impact of true randomness.
When implemented appropriately, a PRNG formula such as the Mersenne Whirlwind will guarantee that the games are both reasonable and also unforeseeable. Nevertheless, typically, the player has to trust that the software has actually not been rigged to enhance the residence side, as its internal functions are invisible to the individual. Appropriately controlled on the internet casinos are investigated externally by independent regulatory authorities to guarantee that their win portions remain in line with the stated probabilities, https://aapanobadi.com/2022/09/20/why-nobody-is-talking-about-casino-and-what-you-should-do-today/ and also this can supply a degree of assurance to the gamer that the video games are fair, presuming the gamer depends on the regulatory authority.
Play Online Casino Games For Real Money
Instead of depending on software to identify the result of the live roulette spin, dice toss, or offer of a card, these video games rely on real-time results. This is possible as the games are streamed in real-time from a land-based casino site or a studio recreated to mimic a land-based gambling establishment. To make certain that players have an easy time playing these video games as well as that the land-based environment is fully recreated, software application programmers consist of cutting-edge features such as the chat feature.
The configuration of these spaces varies from gambling establishment to casino site, with some having a number of pc gaming tables in one area, and also some having a single table in each area.
Will Virtual Reality transform online casinos?
, as well as others providing the games exclusively via their site.
Instances A regular option of gambling video games provided at an on the internet gambling enterprise might consist of: Bonus offers Several on-line casinos supply sign-up bonuses to brand-new gamers making their very first deposit, and typically on subsequent play also. These benefits are a form of marketing that may sustain a cost (possibly sensible in order to attract a brand-new player who might return and transfer much more times), because the casino is essentially providing away money in return for a commitment from the player to bet a specific minimum quantity before they are allowed to withdraw.
Why is it cool to play at the online casino?
These wagering needs are frequently readied to be adequately high that the player has an adverse assumption, exactly as if they had deposited and also not asserted a bonus offer. Online casinos may pick to limit particular games from meeting the wagering needs, either to limit gamers from playing low-edge video games or https://kispestse.hu/Community/profile/Jessica54779368/ to restrict ‘safe’ play (betting as an example both red and also black on roulette), consequently finishing the wagering requirement with a guaranteed revenue after the perk is taken into consideration.
Invite bonus offers sometimes can be found in packages and might be provided to match the first 2 or 3 deposits (First Deposit Invite Reward, Secondly Deposit Welcome Benefit, and so on). They can likewise be tied to certain video games, such as the Welcome Slots Perk or the Welcome Table Games Benefit. The gambling enterprise might likewise offer Welcome incentives for high-stakes gamblers who make a first deposit above the common amount limit.
18 Best Online Casinos in the World: Top Gambling Sites
Read More about
Online Casinos vs Live Casinos: The Pros and Cons – Easy
The Umpire gets a perk when he or she signs up an account at the gambling establishment as well as discusses the Referrer. The Referrer gets a perk when the Referee finishes all the needs, such as making the deposit and betting it a certain number of times. Cashback or insurance policy Cashback or Insurance policy benefits are offered as a portion of all losses in the player’s previous pc gaming task.
You can furthermore locate sites that offer gambling enterprise cashback repayments based upon your losses run into while playing with several online gambling enterprises. Those kinds of cashback bargains are generally repaid to players by the gambling enterprise website that provides those unique cashback offers. No-deposit One of the most preferred type of bonus offer is one that can be declared without the requirement to transfer any of the gamer’s very own money – known as a no deposit perk.
Best Virtual Reality Casinos in 2021
Non-cashable Non-cashable benefits might be called “sticky” or “phantom” rewards. In both situations, the bonus develops a component of the gamer’s balance, yet can not be cashed out.
If the reward is sticky, the gamer will certainly be able to take out just $50. Compensation factors Comps are generally available at land-based gambling enterprises, however also exist online.


text:
It may be easier to get a grant if you are a minority in Australia because a grant for a minority group likely has less competition than a grant for a more general audience. Note the eligibility requirements when applying for any grant in Australia because they can differ for each grant.
How much funding does your small business need? Are you looking to fund your startup or existing business? Get started now with your funding search with our Funding Database. With hundreds of funding programs and $1,449,415,290 in available funding, you should not wait. Register as a member today!
You can also take advantage of the Small Business Startup Assessment Tool below and see the tools and resources you need to succeed at launching your business. It takes just a minute and will also tell you if there may be any funding programs available.


text:
Zachery Andrew Gardiner, 28, of Quarry Road, is charged with two counts of break, enter and theft involving a doctor's office and the offices of the regional hospital foundation.
He is also charged with five counts of possession of stolen property (a laptop, oxycodone, hydromorphone, lorazepam, notepads), two counts of breaching court orders, two counts of possession of drugs, two counts of mischief (damage to a door and damage to a surveillance camera) and a single count of possession of an instrument that could be used in a break-in (a butter knife and multi-tool).
The offences allegedly occurred Saturday at the regional hospital and the nearby Sydney Health Park.
In addition, he is also facing a charge of theft (money) from the Royal Canadian Legion in Glace Bay under $5,000, which allegedly occurred Dec. 3.
Cape Breton Regional Police report that officers were called to the hospital at approximately 9:30 p.m. Saturday regarding a suspicious male in the building checking offices.
Hospital spokesman Greg Boone said Monday security is always a concern and processes in place are reviewed and checked on a regular basis.
Boone said the security response in this case was immediate and appropriate.
Gardiner is scheduled to return to court Jan. 4 for bail hearing.


text:
Progress in treatment for glioblastoma is hindered by the blood-brain barrier (BBB). In genetic mouse models recapitulating brain invasion and abnormal angiogenesis of human glioblastoma, Cai and colleagues demonstrate that optical modulation of the BBB with nanoparticles boosts intratumoural chemotherapy concentration, prolonging survival. We discuss prospects for clinical translation of exemplary innovative techniques.
Challenges with drug delivery for brain cancer
There are several challenges facing the treatment of brain cancer. Gliomas are the most common primary intrinsic brain tumours. Glioblastoma, or a high-grade glioma, is a type of brain cancer that has a devastating prognosis, and for which oncogene-targeted and immune-targeted therapies have yet to make a significant impact in the clinic1. The standard of care remains maximal safe surgical resection, followed by radiotherapy and temozolomide chemotherapy2. One of the most important hurdles to overcome to improve patient outcomes in glioblastoma is to enable therapies to pass through the blood–brain barrier (BBB) and reach the tumour directly for cancer cell killing.
The BBB is made up of microvascular endothelial cells separating blood from brain interstitial fluid, while communicating with brain cells such as astrocytes and pericytes. The BBB is strengthened by tight and adherens junctions between neighbouring endothelial cells, creating a small pore diameter (1.4–1.8 nm) through which only limited particles of a small size can pass. Indeed, around 98% of small molecules and almost all biological macromolecular agents (e.g., antibodies and growth factors) are blocked from passing through the BBB, severely hampering drug delivery to the brain3. Furthermore, delivery to brain cancer specifically has nuanced issues: glioblastomas are heterogeneous cancers from a molecular and histopathological perspective, such that some areas of a tumour have BBB breakdown and increased permeability, whereas others do not. Additionally, the invasive margins of glioblastoma are composed of normal brain tissue infiltrated by cancer cells. In this region, the BBB remains intact, restricting drug delivery to invasive margins that have a unique immune microenvironment and where tumour recurrences are most likely to occur after treatment4.
A plethora of techniques is being developed to improve BBB penetration in glioblastoma (Fig. 1). These techniques include hyperosmolar agents (such as mannitol), tight junction-modulating agents to open tight junctions, inhibitors of drug efflux transporters, and receptor-mediated transcytosis. Another method that is undergoing testing in early-phase clinical trials for BBB opening is focused ultrasound with intravenous microbubbles;5 a recent advancement in this method is MRI acoustic emission-controlled focused ultrasound6. However, novel technologies for BBB opening are critical to ensure maximal drug penetration and minimal toxicity in brain cancer treatment.
While new methods are being explored to improve drug delivery across the BBB, mouse models remain essential tools for preclinical testing of potential chemotherapies for glioblastoma before advancing to clinical trials7. While in vitro systems offer some advantages such as being easier to implement, faster and more cost-effective, in vivo cancer models are essential for recapitulating the three-dimensional organisation of tumours and their interactions within the intricate tumour microenvironment and host response. In this context, glioblastoma mouse models provide a more physiologically relevant setting to study cancer behaviour and drug responses. Several types of brain cancer mouse models exist, including syngeneic transplantation of mutated neural or cancer cells, genetically engineered mouse models (GEMMs), and patient-derived xenografts8. Different models have their own strengths and weaknesses, but a common issue is the inability to fully replicate cancer invasion into the surrounding brain and the aberrant microvasculature of glioblastoma.
Now, Cai et al. introduce an alternative technique to enhance drug delivery into brain tumours, employing optical nanoparticle-based modulation of the BBB. In their study, published in Nature Communications, the authors developed two transplantable glioblastoma mouse models that reflect significant histopathological features observed in patient cancers9. They subsequently demonstrate that optical modulation of the BBB using tight junction-targeted gold nanoparticles can significantly enhance the delivery of the chemotherapeutic drug Taxol into brain cancers. Importantly, this intervention resulted in improved survival rates in mice.
Optical BBB modulation enhances glioblastoma drug delivery in mice
While numerous mouse models of glioblastoma are employed in preclinical research, many fail to fully replicate the genomic or clinicopathological characteristics of human glioblastoma. Cai et al. genetically engineered two mouse brain cancer cell lines and implanted them into the mouse cortex (Fig. 2). These cell lines encompass distinct mutations, with one carrying BrafV600E, Ink4ab/Arf-/-, Pten-/- mutations and the other featuring a different set of mutations (BrafV600E, p53-/-, Pten-/-). With the exception of the relatively infrequent oncogene Braf mutation observed in human high-grade gliomas, the loss of the other tumour suppressor genes is a frequent occurrence in patients’ tumours10. These mouse models accurately portray key clinicopathological aspects of human glioblastomas: one model displays diffuse single-cell infiltration of cancer cells throughout the brain parenchyma, while the second model exhibits highly aberrant tumour vasculature yet limited brain invasion. Together, these two models effectively capture important features seen in human glioblastomas.
In the subsequent phase, the authors assessed the technique of optical blood–brain-tumour barrier (optoBBTB) modulation utilising gold nanoparticles (Fig. 2). They chose paclitaxel (Taxol) as a representative chemotherapy drug, which is applied in clinical practice for various solid cancers but not for glioblastoma due to its poor brain penetration.
Gold nanoparticles with a diameter of 50 nm, designed to target the tight junction protein JAM-A, were intravenously administered to mice harbouring glioblastoma. Subsequently, a transcranial 532 nm picosecond laser was applied to the tumour region to activate the gold nanoparticles and induce temporary weakening of the BBB, likely through increased paracellular permeability related to calcium influx11. This weakening facilitated the delivery of Taxol into the tumour. The BBB modulation demonstrated several attributes: (1) it was region-specific, enhancing drug delivery exclusively to the tumour and not the rest of the brain; (2) it was reversible, as the BBB restored within a single day; and 3) it was repeatable, allowing for three rounds of chemotherapy with BBB modulation and drug delivery to the tumour on each occasion. Notably, this approach not only increased the concentration of Taxol within the tumours, but it also significantly prolonged the survival of mice in both the infiltrative and angiogenic glioblastoma models. This extension in survival time correlated with decreased tumour cell proliferation and increased cell death in the tumours of mice treated with opto-BBTB.
Translation to human brain cancer in the clinic
One limitation of this model pertains to the superficial location of the glioblastomas, situated in the cerebral cortex directly adjacent to the skull’s surface. While certain brain tumours in human patients share a similar location, a significant number are positioned deeper within the brain tissue12. Therefore, it remains to be determined whether optoBBTB modulation can effectively facilitate drug delivery to tumours located at greater depths within the brain. Moreover, it is important to note that mice possess relatively thin skulls compared to humans. As such, parameters for transcranial laser stimulation through thicker human cranial bone will require optimisation for practical application in humans. Proposed strategies for addressing these challenges include the use of near-infrared light-absorbing nanoparticles (as light at this wavelength has greater tissue penetration), or the placement of optical fibres into the cancer surgical cavity, allowing the delivery of side-emitting light to and beyond the tumour margins in patients. Another recent experimental tool is the use of “See-Shells”, digitally designed, transparent polymer skulls that offer long-term optical access to the brain. Although these “See-Shells” have the potential for optical BBB modulation, their application has only been tested in mice so far13.
It is important to recognise the substantial size disparity between glioblastomas commonly observed in patients and those in mice. The translation process to the clinic must also account for the requirement of significantly more repeated chemotherapy doses in human patients. Furthermore, adaptations must consider the alterations induced in tumours due to extended radiation and chemotherapy regimens. Additionally, careful consideration should be directed towards the risk of immunological responses associated with long-term or repetitive treatment of the nanoparticles. Addressing these factors comprehensively will be imperative before successfully transitioning this approach into clinical practice.
To further validate the approach, diverse mouse models like GEMMs and patient-derived xenografts could be explored. While the study employed clinically relevant glioblastoma mouse models to evaluate optical BBB modulation, it remains essential to investigate this technique in glioblastoma models that harbour other common oncogenic drivers with clinical relevance. Examples of such drivers include EGFR amplification, PDGFRA amplification, or an IDH1 mutation associated with a distinct glioma subtype14,15. Moreover, incorporating immunocompetent mice into the study would provide a more realistic scenario, as both the tumour behaviour as well as drug delivery and therapeutic efficacy could be influenced by intact immune responses.
Finally, while Taxol is a relevant drug for glioblastoma whose efficacy is limited due to the BBB, it would be similarly interesting to test other chemotherapeutic drugs and antibodies with similar limitations using this methodology. In particular, antibodies targeting immune checkpoints PD-1 and CTLA-4 (such as pembrolizumab and ipilimumab) have not shown major clinical benefits for glioblastoma and brain metastases, despite their remarkable success in peripheral tumours. This disparity may be attributed to BBB challenges, which could potentially be overcome by exploring methods like optoBBTB16. By exploring the potential of optoBBTB modulation, researchers can gain valuable insights into enhancing drug delivery to the brain and improving the effectiveness of various treatments for glioblastoma and other brain cancers.
Bypassing the BBB to enhance drug concentrations within tumours has long been a formidable challenge in the field of brain cancer therapy. Alongside the development of innovative methods to facilitate drug penetration into the brain, it remains crucial to advance the preclinical modelling of this disease. Such advancements are essential to ensure that emerging tools and therapies can be effectively evaluated, optimising their clinical potential.
In essence, the study conducted by Cai et al. not only introduces mouse models that replicate the invasive and angiogenic characteristics of human glioblastoma but also convincingly demonstrates the effectiveness of optical BBB modulation using nanoparticles. This approach enhances the infiltration of chemotherapy agents into brain tumours, ultimately extending overall survival. Other promising nanoscale technologies for BBB penetration are emerging, such as synthetic protein nanoparticles that leverage the BBB-penetrating capacity of natural proteins;17 BBB-penetrating bacteria loaded with photosensitive nanoparticles that destroy themselves and adjacent tumour cells upon laser irradiation (‘Trojan bacteria’)18; and nanomotors targeting brain endothelial cells, relying on glioblastoma microenvironment chemoattractants to infiltrate the tumour and directly deliver chemotherapy19. While promising, future endeavours must address challenges associated with the clinical application of optoBBTB and similar technologies, particularly the anatomical disparities between humans and mice. Nevertheless, this study, alongside recent advancements in BBB modulation techniques, holds great promise for enabling a new generation of targeted therapies, including oncogene-targeted and immune-based drugs, to effectively penetrate brain cancers.
White, K. et al. New hints towards a precision medicine strategy for IDH wild-type glioblastoma. Ann. Oncol. 31, 1679–1692 (2020).
Stupp, R. et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N. Engl. J. Med. 352, 987–996 (2005).
Wu, D. et al. The blood-brain barrier: structure, regulation, and drug delivery. Signal Transduct. Target Ther. 8, 217 (2023).
Noorani, I. et al. Clinical impact of anti-inflammatory microglia and macrophage phenotypes at glioblastoma margins. Brain Commun. 5, fcad176 (2023).
Terstappen, G. C., Meyer, A. H., Bell, R. D. & Zhang, W. Strategies for delivering therapeutics across the blood-brain barrier. Nat. Rev. Drug Discov. 20, 362–383 (2021).
Anastasiadis, P. et al. Localized blood-brain barrier opening in infiltrating gliomas with MRI-guided acoustic emissions-controlled focused ultrasound. Proc. Natl Acad. Sci. USA 118, e2103280118 (2021).
Noorani, I., Mischel, P. S. & Swanton, C. Leveraging extrachromosomal DNA to fine-tune trials of targeted therapy for glioblastoma: opportunities and challenges. Nat. Rev. Clin. Oncol. 19, 733–743 (2022).
Noorani, I. Genetically engineered mouse models of gliomas: technological developments for translational discoveries. Cancers (Basel). 11, 1335 (2019).
Cai, Q. et al. Optical blood-brain-tumor barrier modulation expands therapeutic options for glioblastoma treatment. Nat. Commun. 14, 4934 (2023).
Ceccarelli, M. et al. Molecular profiling reveals biologically discrete subsets and pathways of progression in diffuse glioma. Cell 164, 550–563 (2016).
Li, X. et al. Mechanobiological modulation of blood-brain barrier permeability by laser stimulation of endothelial-targeted nanoparticles. Nanoscale 15, 3387–3397 (2023).
Larjavaara, S. et al. Incidence of gliomas by anatomic location. Neuro Oncol. 9, 319–325 (2007).
Ghanbari, L. et al. Cortex-wide neural interfacing via transparent polymer skulls. Nat. Commun. 10, 1500 (2019).
Noorani, I. et al. PiggyBac mutagenesis and exome sequencing identify genetic driver landscapes and potential therapeutic targets of EGFR-mutant gliomas. Genome Biol. 21, 181 (2020).
Berger, T. R., Wen, P. Y., Lang-Orsini, M. & Chukwueke, U. N. World Health Organization 2021 classification of central nervous system tumors and implications for therapy for adult-type gliomas: a review. JAMA Oncol. 8, 1493–1501 (2022).
Edavettal, S. et al. Enhanced delivery of antibodies across the blood-brain barrier via TEMs with inherent receptor-mediated phagocytosis. Med 3, 860–882 e815 (2022).
Gregory, J. V. et al. Systemic brain tumor delivery of synthetic protein nanoparticles for glioblastoma therapy. Nat. Commun. 11, 5687 (2020).
Sun, R. et al. Bacteria loaded with glucose polymer and photosensitive ICG silicon-nanoparticles for glioblastoma photothermal immunotherapy. Nat. Commun. 13, 5127 (2022).
Chen, H. et al. A nitric-oxide driven chemotactic nanomotor for enhanced immunotherapy of glioblastoma. Nat. Commun. 14, 941 (2023).
Figures were created with BioRender.com. I.N. is funded by an National Institute of Health Research Clinical Lectureship, a Cancer Research UK Therapeutic Catalyst Award, University College London Biomedical Research Centre, the Academy of Medical Sciences and The Francis Crick Institute, which receives its core funding from Cancer Research UK (FC001169), the UK Medical Research Council (FC001169) and the Wellcome Trust (FC001169). J.d.l.R. is a recipient of a grant from the Prostate Cancer Research (PCR).
The authors declare no competing interests.
Peer review information
Nature Communications thanks the anonymous reviewer(s) for their contribution to the peer review of this work.
Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
About this article
Cite this article
Noorani, I., de la Rosa, J. Breaking barriers for glioblastoma with a path to enhanced drug delivery. Nat Commun 14, 5909 (2023). https://doi.org/10.1038/s41467-023-41694-9

domain: literature


text:
How exactly to Win at Free Slots Online
Free slots refer to online virtual slot machines that you can easily play for fun and without placing hardly any money down. Typically the slot machines which provide this sort of free-slots-experience are the identical to those you will discover in online casinos however will most likely only be accessible through a free or demo mode. It is simple to get around these free slots through the use of different online casino websites, particularly those that feature having bonus codes. A great number of casino websites will have numerous these bonus codes which permit you to access free slots on a continual basis.
When playing free slots probably the most common ways of doing so is to simply spin the reels just as much as you wish in order to obtain spins off winning numbers. Some classic slots machines will reward the player for achieving specific levels of spins with a bonus, for instance five spins or so. There are also some video slots machines which will reward you with credits in case you are able to complete a specific number of spins. In any event it’s just a quick way of filling your money!
Another most popular way to play free slots is by actually transferring your winnings from real money online slots to virtual money within the free slots themselves. That is obviously easier said than done however there are numerous of online slot games that will allow you to do this. The majority of online casinos will use PayPal as the payment way for winning money so this is definitely a good place to begin. In most cases you’ll then be automatically used in the playing account where your winnings will undoubtedly be deposited. Many of these free slots are based on traditional slot games which you would find in your typical land-based casinos, however they often take the shape of video games.
Another of the most popular ways in which to play free slots is the progressive jackpot games. These progressive jackpots can reach up to an astounding US $10 million which is more than enough money to gamble like mad! Some of the most popular free slot games will include a five-reel slots machine. There are literally a large number of different combinations which may be used when you play with these so it is quite common to get a high score. Unfortunately, you can find only a couple of websites that offer these progressive slot machines so if you really want to cash in big then it is advisable to sign up to at the very least many of these websites and try your luck.
Finally, it’s also advisable to be aware that there are video slots which are free to play but not actually part of any online casino. These video slot games are available on several websites and are basically a re-skinned version of these live counterparts. Although these are generally regarded as being poor, this could be worth a look for those who have a budget to invest.
As you would expect, the highest levels of money which may be earned in free slots result from the largest jackpots. Actually, the biggest single jackpot in UK is the slot prize fund that is worth 88 카지노 almost nine million pounds. Other top jackpots are the slots in the Eurostar and London’s Big Ben. One of the reasons why some people play with these slots is because they are unaware that jackpots of this size are not found on most casino sites. As such, you can often get lucky and win a little amount occasionally but ultimately it really is unlikely to make you rich.
Normally, the smaller progressive jackpots will give you about two percent probability of winning. The larger jackpots will give you a better chance of winning however the downside to these is they are much harder to get. It really is worth noting that whilst this can be true, there are some casinos which allow players to change from the small progressive slot games to the bigger jackpots if they so wish. The same applies to the spinners and also the jackpots which are coloured red, yellow or green. They are known as the best known jackpots and come in daily, weekly and monthly formats.
Some of the other popular features which might be found in free online slot machine game games are the bonus features which come due to winning a specific amount. A few of these bonuses will be cash rewards while others may be in the form of gift vouchers or entries into draws. There are also spins which may be won whereby a certain amount of coins are exchanged for a prize. Much like all free online slot machine game games, winning takes a strategy. Playing carefully and learning how jackpot icons work often means you stand a much better chance of winning some money off your slot machine game games.

domain: hobby


text:
RINSAWATI, DWI (2009) PENGARUH KOMPOSISI NPK DAN DOSIS PEMUPUKAN TERHADAP PERTUMBUHAN ANTHURIUM DAUN WAVE OF LOVE (Anthurium sp.). Other thesis, University of Muhammadiyah Malang.
Download (88kB) | Preview
Research this aim to study of composition and dosage of NPK fertilizer which both for growth of Anthurium sp. Benefit of research this can gave information of usage composition and dosage of NPK fertilizer which both for to growth of Anthurium sp. Hypothesis anticipate there are significant effect interaction from composition and dosage of NPK fertilizer to parameter growth of Anthurium sp, anticipate the NPK composition can increase growth of Anthurium sp., anticipate the dosage NPK fertilizer can increase the growth of wave of love anthurium (Anthurium sp.) Research hold on Landungsari Kodya Malang in ± 550 m dpl, this research was done in November 2008 to Mart 2009. The equipment that used in this research is hoe, plastic spoon, weight, ruler, caliper. The object of this research is the seedling wave of love anthurium, pakis, charcoal of chaff, organic fertilizer, NPK (6:13:25) NPK (13:13:13), NPK (18:9:10), dekastar plus fertilizer, polybag, dithane and bavistin of fungisides, mipcsin and coracron of insectisides. The experiment to used the random block design (RAK) by two factor that in 3 repetition. First factor is composition of NPK Fertilizer (P) which consist of 3 level that is: P1: NPK composition (6:13:25), P1: NPK composition (13:13:13), P1: NPK composition (18:9:10), Second Factor is dosage of NPK fertilizer which consist of 4 level that is: D0 control without fertilization, D1 dosage of fertilizer 1,5 g/plant, D2 dosage of fertilizer 3 g/plant, D3 dosage of fertilizer 4,5 g/plant. Result of the experiment showed that there were significant interaction between of composition and dosage of NPK dekastar plus fertilizer to parameter height of plant and wide leaf of anthurium. Combination of composition NPK fertilizer (18:9:10) with dosage 4,5 g/plant give the which result good.
|Item Type:||Thesis (Other)|
|Subjects:||S Agriculture > SB Plant culture|
|Divisions:||Faculty of Agriculture & Animal Husbandry > Department of Agronomy|
|Depositing User:||Anggit Aldila|
|Date Deposited:||27 Jun 2012 07:31|
|Last Modified:||27 Jun 2012 07:31|
Actions (login required)

domain: chemistry


Report by Nishapati Nayak, Sunabeda: The Third National Handloom Day was observed at the permanent campus of the Central University of Orissa, Sunabeda today, with the objective to generate awareness about the importance of handloom industry and its contribution to the socio-economic development of the country in general and to promote handlooms, income of weavers and enhance their pride in particular here today at its Sunabeda campus. The programme was organized by the Directorate of Field Publicity, Ministry of Information and Broadcasting in collaboration with the Central University of Orissa, Koraput and the Ministry of Textile, Government of India. Prof. Sachidananda Mohanty, Vice-Chancellor of the University inaugurated the programme as the Chief Guest and delivered a talk on Importance of the Handloom Industries in the social economic development of the country. Shri. Mahendra Prasad Jena, Field Publicity Officer, Bhawanipatna delivered the welcome address. Among others Shri. Navneet Singh Sekhawat, Technical Superintendent, Weavers Service Centre, Bhubaneswar and Shri Narendra Kumar Suna, Sub-Registrar, Co-Operative Society, Koraput addressed the programme. On this occasion Hon’ble Vice-Chancellor Prof. Mohanty felicitated six eminent weavers of the region.
Prof. Mohanty, in his energetic address emphasised on the importance of the handloom industry in the 18th century and its struggle during the British era. He also talked about how the British East India Company took over the Indian civilization. He said “Handloom is the symbol of freedom of our country and to know handloom we need to discover our civilization, our culture we need to discover India. We need to discover our handloom together, discovering handlooms means discovering our nationalism. To celebrate handloom means to celebrate the great nation called India”. He motivated the students to know the glorious history of the country and live life with patriotism and feelings of nationalism. He said ‘Central University of Orissa is the lamp of education in this region’.
Prof. Mohanty felicitated six eminent weavers of the KBK region on this occasion including one Sant Kavir awardee. They are the recipient of national award for ethnic handloom product Shri. Madhu Panika, Sh. Bidyadhar Mahanta, Sh.Gobardhan Panika, Sh. Khagapati Panika, Smt. Jema Panika and Shri Baidyanath Samarath.
Shri Jena in his welcome address requested and motivated the students to create awareness regarding the use of handloom. Mr. Suna in his address talked about the glorious history of handloom in Odisha and appealed the gathering to recognize our tradition and culture for the development of the handloom. Mr. Sekhawat talked about the objectives to promote handloom as it creates employment opportunities at the rural area and generate employment opportunity to the women’s at the rural villages of the country. He also talked the important steps taken by the Government to promote the handloom.
Dr. Phagunath Bhoi, Public Relations Officer delivered the vote of thanks. Ms. Mercy Mousmi Takri, student counselor compeered the programme. All the students, faculty and staff of the University and weavers of the region were present at large.


THE US has avoided economic calamity after a budget deal was approved.
IT prevents $600m (€452m) worth of spending cuts and tax rises that would have pushed the country off a 'fiscal cliff' into recession.By a vote of 257 to 167, the Republican-controlled House of Representatives approved a bill that fulfils President Obama's re-election promise to raise taxes on top earners.
The Senate had passed the measure in a rare New Year's Day session and Mr Obama (right) said he will sign it into law shortly.
The vote was a reversal for House Republicans, who were in disarray despite winning deep cuts in budget fights.
However, the President faces more budget battles in the weeks and months to come.


text:
It seems I have a bit of a hot sauce problem. The other day, I came across some beautiful cayenne peppers at the market and a vision of them pureed into a lusty, tangy bottle of lava swam through my thoughts. I bought a few handfuls, chopped, salted and pounded them into pliancy, and then set them aside to see what happened.
Fermentation took off overnight, and by the end of the next day the brine was already so tasty that I asked my boyfriend to pick up any hot peppers that looked interesting at the Union Square Farmers’ Market. He came back with just a pint of pretty red jalapeños – which I subjected to the same treatment, this time with a bit of ginger.
Three days later, both jars of future spicy condiment bubbling away, I strolled by the Farmers’ Market myself and found a gentleman with an entire table dedicated to beautiful chiles of varying heat. I walked away with a bagful of more long cayennes and a handful of red Anaheims. I’ve now got one sauce pureed and bottled, two jars bubbling away, and an idea for a new item to include in holiday gift baskets this year. Continue reading
After a few days of relief, it’s back to being hot and sticky here in New York. Just the thing to put me in the mood for a frosty, fizzy drink with a gingery bite.
I’ve currently got two bottles of this potion getting bubbly on the counter – known variously as home fermented ginger ale or ginger beer (I’m calling it ale because I did not use any packaged yeast, but if you know any other reason for the distinction I would love to hear it).
This is so easy to make, the hardest part is not rushing the process. I’ve done it once before but did not have a fermenter with a tight enough seal, so was a bit disappointed with the carbonation. I’m much better prepared this time with swing top bottles and rubber gaskets. Once these are done fermenting, I’ll be back with a write up.
It’s been a long break! We moved and, with the general chaos that ensued, I haven’t been organized enough to get busy on new fermenting projects. I have been trying to bake a loaf of sourdough every week and have some updates to my first post coming soon. Continue reading
This post is a bit after the fact, but I wanted to update on my Sweet Yellow Eyed Bean Miso, with the exciting news that it is, in fact, possible to make miso at home. And, aside from a little patience, there’s almost no special skill required! Continue reading
Maybe I should just rename this blog “Sourdough and Kimchi.” Even though I was pleasantly surprised with the first loaf of sourdough I made using nothing more than flour, water, salt and naturally occurring yeast and bacteria, I was coveting those gorgeous boules with the open, airy insides and all those pockets for trapping extra butter or drizzles of honey.
It seems that one of the secrets to this is increasing the hydration (the ratio of water to flour) of the dough. I could not read enough good things about the Tartine Country Bread recipe on the internet, and now I know why. Although it’s time consuming (not counting the time to warm up and resume daily feedings of my starter, about 36 hours from start to finish), the process is pretty simple and most of that time is just waiting for fermentation to do its thing. And look at the gorgeous crumb of this loaf!
I plan on trying this a few more times before sharing a more thorough write up, but the difference this technique made was so exciting that I couldn’t wait to post this picture.
My sourdough starter has been hibernating in the refrigerator for about a week and a half. The schedule is to feed it every Tuesday morning until I’m ready to bake, taking out about 25 grams of starter and discarding, and stirring in about 25 grams each of flour and water. The last two feedings have been with rye flour, to prepare for a rye sourdough next (or maybe some rye bread to try and reproduce the wonderful smørrebrød we recently had in Copenhagen).
Looks like it’s having a grand time with lively dreams so far!
There are quite a few vessels bubbling away in our kitchen right now: miso, sourdough starter, and a newly fermenting beer (more on that in another post). But, after that first batch, I just couldn’t wait any longer to get another kimchi fix. I wanted to try a few new ingredients for round two just to see what happened. Continue reading
In the last few days I’ve learned that there seem to be as many different techniques and ingredient lists for making sourdough bread from a starter as there are bakers. Everyone has their own way of feeding the starter to get the yeast at their most voracious, their own slightly differing proportions of flour, water, starter and salt, a favorite blend of flours, and a variety of ways to proof, knead and bake the dough. Continue reading

domain: food


text:
Girls Water Polo on to NCS
November 8, 2010
For the entire Fall season the girls water polo team has been a force to be reckoned with. They won first in league only losing 2 games, breaking Mission San Jose High’s winning streak. The girls worked hard all season to reach their goal of NCS, no other girls polo team has ever gone past the first round. Ending their league season, the girls were ranked 4th in NCS. Coach Cameron Bramhst brought up three players from the Junior Varsity team to play in the NCS rounds (Juniors Cali Bachelder, Brooke Eicher,and Jesse Reist). They played their first NCS game against Berkley on Saturday, winning 17-1, advancing them to the next game on Tuesday November, 9th. Their second round game on Tuesday will be played at Miramonte High against Clayton Valley at 5:45PM.


text:
The Sleeping Cell problem is a particular type of cell degradation in Long-Term Evolution (LTE) networks. In practice such cell outage leads to the lack of network service and sometimes it can be revealed only after multiple user complains by an operator. In this study a cell becomes sleeping because of a Random Access Channel (RACH) failure, which may happen due to software or hardware problems. For the detection of malfunctioning cells, we introduce a data mining based framework. In its core is the analysis of event sequences reported by a User Equipment (UE) to a serving Base Station (BS).
The crucial element of the developed framework is an anomaly detection algorithm. We compare performances of distance, centroid distance and probabilistic based methods, using Receiver Operating Characteristic (ROC) and Precision-Recall curves. Moreover, the theoretical comparison of the methods’ computational efficiencies is provided. The sleeping cell detection framework is verified by means of a dynamic LTE system simulator, using Minimization of Drive Testing (MDT) functionality. It is shown that the sleeping cell can be pinpointed.


text:
Thursday, January 10, 2013
Little grey side tables
They're kind of like your favorite little black dress, only more fun.
Little grey side tables finished in CeCe Caldwell's Pittsburgh Gray paint and clear wax.
I wish I had before photos. What is wrong with me? Laziness? They were so hideous. For more on their before, check out this post.
Now they're done! The center panel of fabric is super cute, covered by a 16x20 pane of 1/8" glass and trimmed out in 1/4"x 2" wood painted to match the tables.
I don't think I told you this...my original vision for these tables was to turn them into little ottomans. But after I got the center panels upholstered with foam underneath I wasn't happy with the result, so I took the tables apart and kind of started over.
I also considered using burlap for the fabric in the center. It probably would have made selling them easier, but the fabric that's in there now is so unique and textural, I just couldn't pass it up.
It's funny how a simple Goodwill purchase like these tables can take on a life of its own.
These two tables will be for sale at the Sweet Pea Boutique in Fountain, beginning at their grand opening on January 26th!


Buoyed by a hugely successful Christmas, the discount supermarket has just launched a new tongue-in-cheek advertising campaign to promote unbeatable prices to British shoppers. Launched on 2nd January, the fully integrated campaign builds on Aldi’s distinctly quirky humour with ‘Two deer’ and Duncan, the duck with a rather large ‘bill’.
Matthew Barnes said: “We start 2017 in confident mood and have just launched a new marketing campaign to communicate our price leadership to our customers. We have 70 new Aldi supermarkets opening across the UK this year and our 700th store is due to open in February. As Britain’s fastest-growing supermarket we remain committed to meeting the strong demand across the country for new Aldi stores.”
Last week Aldi announced new market-leading rates of pay, reaffirming its position as the UK’s highest-paying supermarket employer. From 1st February, employees will earn a minimum of £8.53 per hour nationally and £9.75 per hour in London.


New firearms squad created
A NEW Queensland police squad has been formed to track down the source of illegal firearms.
The five-member team will be part of the organised crime investigation unit, says Police Minister Neil Roberts.
The squad's prime target is determining the source of illegal firearms.
Police Commissioner Bob Atkinson said the involvement of firearms in crime had been relatively stable in the past five years.
However, the number of firearms stolen in Queensland increased last year (2011).
"The squad will provide assistance and support to the eight Queensland Police regions across the state," Mr Roberts said.


People assume that state benefits are for those who need financial assistance and support. This might be true in most cases, but not all benefits are means tested.
For example Attendance Allowance is to help people who need extra assistance. The criteria are based on the ability to complete personal care tasks to establish a need for support in the home. It is not means tested.
Many pensioners would struggle without the State Pension. However, it is obviously a universal benefit available to all who have paid the required level of National Insurance contributions. Some people are unaware that they may have not paid enough NI and will get a rude awakening when they receive a reduced pension. A huge pitfall which can be avoided by asking for a pension forecast today!
Other benefits are available to people with different levels of income. Some families would not qualify for Working Tax Credit as their income is too high but can still receive Child Benefit. This benefit is lost if either parent earns more than £50,000.
The rules are complicated and sometimes people are unaware that they could be receiving a benefit. Age UK have produced a really simple online calculator which can help you through the minefield of rules.
There are huge debates to be had around the future sustainability of universal benefits such as free bus passes, winter fuel allowance and free TV licence before we even start on the State Pension but for now, they are there for the taking.


text:
The premises are available by way of an assignment of the existing lease expiring 17/06/2028, with the option to break on 17/06/2023. Alternatively, the premises are available by way of a sub-lease.
Marketed by CBRE
• Located within the heart of Guisborough town centre, the gateway to the North York Moors National Park • The unit has suitability for a variety of uses under Use Class E • First Floor space suitable for stores or possible residential use • Nearby...
Marketed by @retail

domain: geography


Formula 1 stakeholders are engaged in a vital tug of war over how much the incoming budget cap should be reduced by ahead of its introduction next season.
F1 teams had agreed on a $175m cost cap to be introduced in 2021, but this is set to be lowered as part of the bid to reduce the impact of the global health crisis and its demolition of the 2020 calendar.
Several measures have already been agreed, including postponing new technical rules to 2022, but there is a collective desire to cut costs further and protect the championship and its teams beyond the current situation.
It is understood that all 10 teams are either in favour of reducing the cost cap to $150m or are at least open to it, subject to certain conditions.
Reducing the cost cap is a complex issue with many variables, and a meeting between teams, F1 boss Chase Carey and FIA president Jean Todt on Monday ended with an agreement to consider the issue further and reconvene later this week.
The means of achieving a reduction, and what it means for the entities that carry the financial burden of developing components like engines and gearboxes, are at the heart of the division between teams.
The two-tier cost cap proposal
One complication Ferrari has raised is the bigger teams carry out expensive research and development work and then supply parts such as gearboxes and suspension to other teams.
In the cost cap regulations outlined by the FIA, there are adjustments that may be made if a team sells components to a customer.
However, these terms are undefined. Ferrari was relaxed about this while the cap stands at $175m, but wants this part of the financial regulations altered with precise terms, values and policing methods if the cap is to be reduced.
It would effectively create a two-tier budget cap that takes into consideration the R&D and infrastructure costs bigger teams incur.
If these costs can be quantified for various components, then they would be added to the base budget cap for the manufacturer and subtracted from that of the independent team.
The logic is that without such a balancing mechanism, an independent outfit could commit to the same spend as a manufacturer without such high costs, and therefore a bigger proportion of its budget could be spent competitively against the manufacturer.
But it appears that a budget of $150m, and certainly lower than that, is considered the point at which a competitive advantage could be gained, because smaller teams would be capable of reaching that budget whereas at $175m there would still be a buffer for the big teams.
Should the split in limits be accepted, they could then be reduced further over the next few years, as long as a buffer between manufacturer and independent teams is maintained to allow for the extra development expenses.
Is a big reduction necessary, or just opportunistic?
The basic argument for a major budget cap drop is that less spending is good for all teams, especially in the current climate, and it would create a fair fight.
McLaren boss Zak Bown proposed a limit as low as $100m, with a compromise of around £130m considered acceptable.
He told the BBC last week that without “an aggressive enough budget cap” teams that struggle to reach the limit and fall behind will question their involvement.
Brown added that if smaller teams do not want to be part of F1 for those reasons, then there will not be new teams waiting in the wings to replace them either.
A cap as low as $100m, as McLaren proposed, would mean all teams can spend up to the limit, but is considered unrealistic because of other costs incurred by bigger manufacturers, as outlined above.
Ferrari also claims it is concerned by the prospect of significant redundancies, which it says could pose a major problem with Italian employment law.
The bigger teams are also concerned that lowering the budget cap beyond $150m is not about protecting teams, but simply competitive opportunism.
The logic put forward by bigger teams is that achieving meaningful reductions for everybody is the best course of action, rather than pegging back those with larger budgets because there is an opportunity to do so.
They argue the budget cap itself may not necessarily address teams’ financial plights, whereas wider freezing of components and other measures can approach the matter from a broader perspective.
A significant reduction in the financial commitment engine manufacturers have to make, given they supply engines at a price that guarantees an operational loss, is also desired.
And delaying the new rules to 2023, as tabled by Red Bull, would prevent significant spending to carry out a complete redesign at a time when budgets are so sensitive.
However, a further rules delay does not appear to have the support of F1 or the FIA. It will be discussed again at a later date, but not before the higher-stakes budget cap debate is resolved.


text:
Dogs are fascinating creatures, and as pet enthusiasts, we often find ourselves pondering the peculiarities of their behavior. One such curious behavior that many dog owners have encountered is the unexpected moment when their furry friend burps right in their face. In this comprehensive guide, we’ll delve into the reasons why does my dog burp in my face and shed light on the intriguing world of dog communication.
Understanding Dog Communication
Canine Expressions: More Than Words
Dogs communicate not only through barks and tail wags but also through subtle body language and sounds. Understanding these expressions is crucial for building a strong bond with your pet.
The Significance of Burping
Just like humans, dogs burp as a natural part of the digestive process. However, when it happens near their human companions, it may convey specific messages that go beyond simple digestion.
Why Dogs Burp in Your Face
Dogs are known for their unconditional love, and burping in your face might be their way of expressing affection. It’s a form of bonding that signifies trust and closeness.
In the canine world, hierarchy matters. Your dog burping in your face could be a submissive gesture, acknowledging your role as the pack leader.
Dogs thrive on attention, and some may resort to unique behaviors, like burping in your face, to grab your focus and affection.
Mimicking Human Behavior
Dogs are incredibly perceptive. If they observe their human counterparts making certain sounds, they might try to mimic these behaviors as a way of connecting with their owners.
In some cases, burping could be a result of digestive discomfort. It’s essential to monitor your dog’s overall health and dietary habits.
How to Respond to Your Dog’s Burping
When your dog burps without causing any discomfort, offer positive reinforcement. This encourages the behavior if it stems from affection or a desire for attention.
Check for Health Issues
If burping is accompanied by signs of distress or changes in behavior, consult with a veterinarian to rule out any potential health issues.
Maintain a Healthy Diet
Ensure your dog’s diet is suitable for their breed and size. Sometimes, dietary adjustments can alleviate digestive discomfort.
Embracing the Quirks
Cherishing Your Dog’s Individuality
Every dog is unique, and their behaviors contribute to their personalities. Embrace the quirks that make your dog special.
Strengthening the Bond
Understanding and accepting your dog’s behaviors, even the quirky ones, can strengthen the bond between you and your furry friend.
Resources & References
Dog Burps in My Face – Unveiling Canine Communication
In this engaging video, you’ll witness firsthand the adorable quirks of dogs, including why they may burp in their owner’s faces. Understanding these behaviors adds a layer of connection to your bond with your furry friend.
FAQs – Why Does My Dog Burp in My Face
Does a dog’s burp mean anything?
Yes, a dog’s burp can indicate that they are swallowing too much air, which can happen when they eat or drink too quickly.
Do dogs burp when happy?
No, dogs do not burp when they are happy. Burping is typically a sign of discomfort or indigestion.
Do dogs burp when nervous?
No, dogs do not burp when they are nervous. Burping is usually caused by physical factors, such as swallowing air or eating certain foods.
Why does my dog burp when begging for food?
Dogs may burp when begging for food because they are anticipating eating and their stomach is preparing for digestion.
Do dogs cry when sad?
Yes, dogs can cry when they are sad, just like humans. They may also whimper, howl, or make other sad vocalizations.
Why does my dog nuzzle my stomach?
Dogs nuzzle their owners’ stomachs for several reasons, including to show affection, to seek comfort, or to mark their territory.
What animal burps when happy?
No animal is known to burp when happy. Burping is typically a sign of discomfort or indigestion, regardless of the animal.
Why do dogs sigh when you kiss them?
Dogs may sigh when you kiss them for several reasons, including to express contentment, to relax, or to communicate that they want to be petted.

domain: pet


text:
The very first landscape architecture program in China was initiated at Tsinghua University, one of the most distinguished universities in the Nation. Rapid population growth and environmental challenges over the past thirty years…
Size: 7.3″ x 10″ (Portrait)
Binding: Hard Bound
Publication Date: Fall 2017
Rights World: Available
— OR —
”One of the most distinguished universities in the Nation.”
7.3" x 10" (Portrait)
The very first landscape architecture program in China was initiated at Tsinghua University, one of the most distinguished universities in the Nation. Rapid population growth and environmental challenges over the past thirty years have driven an ever-increasing need for landscape design. Tsinghua University pioneered the expansion of landscape architecture education in China. With its international vision and broad insight into local practice, targeted research, excellent student work, and rich publications and papers, Landscape Architecture at Tsinghua University: Sixty Years of Excellence, provides a full and vivid picture of the landscape program at Tsinghua.
The book provides an overview of the department’s milestone achievements in retrospect as well as its influential contributions in current days, including the establishment and development of the program, a description of its educational philosophy integrating practice and research, a collection of award-winning projects by faculty members and a compilation of books, awards, published studies, and monographs. A thorough reflection on the accomplishments and great work done since the establishment of the Department of Landscape Architecture at Tsinghua University, it also provides a broad scope of hot topics related to environment and sustainability in regards to China’s current development.
COMPANY HOME ABOUT NEWS CONTACT CATALOG NEWSLETTER TWITTER INSTAGRAM LINKEDIN FACEBOOK
COMPANYHOMEABOUTNEWS CONTACT NEWSLETTER
QUICK NAVIGATIONARCHITECTUREART, PHOTOGRAPHY, & DESIGNINTERIOR DESIGNLANDSCAPE ARCHITECTURE / SUSTAINABILITYMONOGRAPHSERIESURBAN DESIGN
CONTACT USUSA - San Francisco Bay AreaTel: +1(415) 883-3300USA - New YorkTel: +1(646) 322-2466Asia - Singapore & ChinaTel: +(65) 9068-1860Tel: +(86) 755-84556863
CONTACT USUSA - San Francisco Bay AreaTel: +1(415) 883-3300Asia - Singapore & ChinaTel: +(65) 9068-1860Tel: +(86) 755-84556863
© 2023 Applied Research And Design / ORO Editions. All Rights Reserved.

domain: library


COSTA RICA NEWS — The Tribunal Contencioso Administrativo (Administrative Court) issued an injunction against the collection of the 2015 Marchamo (circulation permit), giving the State and the Instituto Nacional de Seguros (INS) three days to respond.
The injunction does not halt the actual collection. Not yet, anyways.
Basically the Court is allowing all State and the INS three days to respond in writing against the appeal filed by Movimiento Libertario legislator, Otto Guevara, who, like many vehicle owners object to the increase in the “fiscal value”, a value that is used to calculate property tax on vehicles that included in the payment of the annual Marchamo.
The press office of the Corte Suprema de Justicia (Supreme Court) said that once the responses are received, the judge will then decide whether the injunction will suspend the collection or if things will remain the same.
Every December, owner of vehicles are required to pay the Marchamo, an amount that includes the mandatory insurance provided by the INS and the property tax based on the fiscal value set by the Ministerio de Hacienda (Ministry of Finance). The property tax represents more than half of the total cost of the Marchamo.
The INS is the autonomous state agency responsible for the collection of the Marchamo through its agent network and financial institutions across the country.
The Marchamo payment is due by December 31. On January 1, late fees and penalties are added and drivers in a vehicle without the current Marchamo face a ticket and possible seizure of the license plates and/or vehicle.