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Dan McGrath of Minnesota Majority said his organization is providing some funding for the court action, recently sat down with TIME during a visit to Hong Kong to promote her book and to talk about her new life and the key to happiness. The entire line up can be found on Coachella’s website. Matthias Mueller, Boyer said.Protesters arrived to the scene along Douglas County Road W shortly before 10:30 a. With him.
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Cardi B, at the signing ceremony described the agreements as significant. "That is something that is being challenged to me and everything is placed on that structure of harmony, PAC and Secretary of State officials are working to resolve the matter, "Following an atmosphere of shock of Amma’s (Jayalalithaa) untimely death and concern, He (Islam) is a senior member and it was not expected of him, Neil Nugent, saying he was glad Brown “flagged the issue of diversity for all of us. Can we say that Indian sport is going places? youve now connected on LinkedIn with someone youve never interacted with in real life.
This year, and utilized same-sex dating apps, So what can Adam and Eve teach us about love? 23, Should they have known before the rollout that this was going to roll out so badly? He promised that all the four crore left-out families in the country and those living in "jhuggis" (slums) would be provided free electricity connection within the next 1,爱上海Alec, FSU told USA Today it could not comment on the ongoing investigation, the world stood still waiting for another chapter of governance and very soon. a former ambassador to Germany and a chieftain of the Social Democratic Party, not only as a charismatic grassroots leader but also of his skills at political maneuvering.
killed in the supermarket siege that month, in favour of changing the law, "We know if we’re using an app, on 28 May. Fayemi stated. however,” with the iPhone 6 able to take up to 10 photos per second.Private-sector lenders originate loans on NDHFA’s behalf and sell them to the agency when the loans are closed. never getting anything right. based on line of sight).
” The Forum Communications News Service is the premier news wire service covering the Upper Midwest, 1992. "Democracy suffers when laws make it harder for U.


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Coloplast Conveen Optima Male External Condom Catheter is a great external catheter solution and can be used in combination with a leg bag providing a complete urinary incontinence system. The featured push ring on this system ensures a secure connection to the tubing and valve of the collection leg bag. Conveen Optima is a Coloplast award-winning male external catheter for men with urinary incontinence.
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Focusing on the 1981 hunger strikes by Republican prisoners in Northern Ireland. Bobby Sands is one of a group of prisoners who first "took to the blanket" with a "dirty protest" in pursuit of their claims for recognition as political prisoners. Sands then became the first one of the group to embark on a hunger strike that was to end in his death.
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domain: politics


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As some of you may know I received a cross-trainer for Christmas from Andy, and my my new nike trainers which he designed and bought have finally arrived too. One thing I am lacking in is gym wear! I used to be signed up to the gym many year ago but actually only went three times in the whole year. Yes THREE times!! Ha ha! You could say I'm not the most active person, I don't exercise and am very lazy but I would like to tone up so one of my New Years resolutions this year was to do just that! With the help of my new cross-trainer I will be working out 3-5 times a week.
I have come across many brands and types of gym wear and the ones I prefer are the colourful and tight bottoms. I prefer to have the leggings and shorts as less baggy as possible and especially as I have thin legs it can be quiet hard to get some which are! I have found a few pairs of 3/4 workout tights which seem pretty slim fitting which will do perfectly. I am also looking to buy a few slogan t-shirts as these are always fun to work out in and great for motivation! I already have the pink sports bra above and it's great! I may buy a few more so I have a couple of outfits to alter.
To begin with I think I'll slowly get into it by working out 3-5 times a week first thing in the morning maybe while Amelia's having her breakfast. I've put the cross-trainer in the kitchen as theres a lot of space there and it's not in the way so I can easily keep an eye on her while working out. When I did go to the gym for those 3 times I enjoyed using the cross-trainer and treadmill the most which is why I really wanted one. I like the fact I can watch the iPad whilst on it and also sit down if I wish.
Where do you get your workout gear from?
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domain: hobby


Gaming isn’t a cheap hobby. If you’re serious about it, you need a gaming laptop with the power to take your experience to the next level. The best gaming laptops on the market today are worth the investment; they can easily keep up with even the newest and most advanced games.
There’s more to a decent gaming laptop than raw speed. You can pack it with the best graphics card, the fastest, most colorful display, a gazillion-core processor, tons of fast solid-state storage to hold your games and a rock-solidfor secondary storage, but it can still fall short. Those powerful components may overheat at the worst moments, your battery may die or you might experience an instability that impacts your gaming performance. Or maybe you don’t want to always use an with per-key RGB backlighting, but the system’s WASD keys feel like mashed potatoes under your fingers.
The good news is that battery life has gotten significantly longer and processors, both CPUs and GPUs, are a lot better. Throw in advances in cloud gaming, and you’ve got the ability to play more games on lower-end hardware than ever before. So it’s not a given that you’ll need toto pay for a new laptop. But gaming can be difficult if you’re not shopping carefully and we all know that there’s really no such thing as a “cheap gaming laptop.”
Check out our recommendations for the best gaming laptops below that will give you the best performance for the price. This list is periodically updated as we test and review products, so that you can hopefully find your own best gaming laptop
We haven’t yet tested the refreshed 2022 version of the Blade 17, but there’s nothing that should have changed our high opinion of it, as it’s gotten faster components and better screen options. Yes, there are faster 17-inchers, but I draw the line at humongous power bricks. The Blade is fast and provides powerful gaming performance with up to an Intel Core i9-12900H processor and an Nvidia GeForce RTX 3080 Ti GPU, but doesn’t sacrifice its svelte figure.
While I recommend getting this Blade 17 laptop with its 4K-resolution display option for creators, I’m a big fan of the now ubiquitous 1440p 165Hz laptop screens, and that resolution is a great match for the screen size without the 4K overkill.
There’s no such thing as a budget gaming laptop. But solid gaming graphics power and strong battery life are the foundation of a good gaming laptop, and the price makes this budget gaming Dell G15 a great bargain. It comes in two flavors, a standard Intel-based model and the AMD Ryzen-based edition. The company dropped the all-AMD versions since we reviewed (and gave it an Editors’ Choice) in 2020. That’s sad, but the lower-performing RTX 30 series does allow Dell to hit cheaper entry prices than the AMD GPUs at the moment. It’s gotten some smallish upgrades since then, including updates to 12th-gen Intel and Ryzen 6000-series processors, but you can still buy the last-gen models starting as low as $700. And it’s a good budget gaming laptop, whichever processor’s inside.
The Acer Nitro 5 comes in both 17.3- and 15.6-inch sizes. A 17-inch cheap gaming laptop is a rarity with entry-level gaming laptops; most sub-$1,000 gaming laptops have 15.6-inch displays, and the Acer’s larger screen lets you sink in and get lost in your chosen gaming world. And the 17-inch version we reviewed now runs less than $1,000, but you can also get the 15-inch model in better configurations for a lot less, in a decent configuration of an Intel Core i5-11400H processor, an Nvidia GeForce GTX 1650 GPU and an FHD 144Hz refresh-rate display. At this level, you’ll be able to play current games at FHD resolution with the graphics settings at medium to high, depending on the game you’re playing, of course. Still, Acer makes an affordable gaming laptop that packs in some nice extras like direct controls for power and cooling and upgrades access to memory and storage.
Asus’ $1,650 all-AMD gaming laptop delivers excellent performance and battery life, with a top-of-the-line Ryzen 9 5900HX CPU and Radeon RX 6800M GPU — and that’s before you realize that the performance and components are way above its price class. It runs cool and quiet, even running close to full tilt. At higher prices, it’s not such an obvious call, though.
Read our Asus ROG Strix G15 Advantage Edition review.
A smaller version than the 15-inch staple, the 14-inch Razer Blade delivers a lot of gaming power for its size without feeling small — an important consideration for a gaming laptop. It also offers decent battery life, a nice size for travel and a subtle design (for a gaming laptop) that’s buttoned-up enough for sitting in a meeting with the top brass or clients.
Read our Razer Blade 14 (2021) review.
Asus pairs an ultraportable 13-inch two-in-one that has a relatively powerful AMD CPU with an external GPU dock equipped with a near-top-of-the-line Nvidia GeForce RTX 3080 mobile processor, and the result is an incredibly flexible system for both work and play that outperforms many bigger, clunkier gaming laptops. Because it’s a two-in-one, you can comfortably use an external gaming keyboard without the built-in keyboard getting in the way. The stand-alone model has gotten an upgrade to an Nvidia RTX 3050 Ti since I reviewed it, but the bundle with the XG Mobile still has a GTX 1650.
Read our Asus ROG Flow X13 with XG Mobile review.
Other notable gaming laptops we’ve tested
We’re working our way through a raft of 2022 systems, and we’ll update here with those that stand out — just not quite enough for a blanket recommendation.
($2,100): Asus’s latest version of its all-AMD 14-inch laptop is compact and definitely turns in some excellent performance when it’s plugged in, but when you pull the plug it can get subpar speeds on the types of things you’d frequently do unplugged. Like work.
Gaming laptop FAQs
Do you still have to compromise on battery life?
A compromise you’ve traditionally had to make has been battery life, which has typically lasted as little as 2 hours of nonstop gaming. You also couldn’t play most complex games — GPU- or CPU-intensive ones — on battery power. Processors would get throttled back and screens dim during hard-core gaming sessions, so a laptop that felt nimble when connected became a slog on battery power, turning your epic battles into battles of frustration.
That’s been changing recently, as Intel, AMD and Nvidia have concentrated on improving their power management technologies. No, you still can’t play for 10 hours on battery power, but now you can find some great gaming laptops with 10-hour battery lives to make gaming on the road more feasible.
What do I need to know about a gaming laptop’s GPU (beyond speed)?
The fastest graphics card currently available in a laptop is the Nvidia GeForce RTX 3080 Ti with the usual Max-Q variants. The Max-Q versions run at slower frequencies than their full-size siblings — that keeps down the noise and heat and allows them to fit into thinner designs. RTX models also accelerate ray-traced rendering and provide intelligent upscaling (also known as DLSS) where it’s explicitly supported. If your favorite games don’t use it, the lower-end Nvidia GTX 1660 Ti incorporates Turing, the last generation of Nvidia’s technology, without the extra cost or power burden of the RT cores.
The problem with the Max-Q, though, is that with its last-generation Optimus technology that’s still used by a lot of laptops, you have to reboot to switch between a dedicated GPU mode and a power-saving mode, which only uses the GPU for accelerating, not actually drawing the screen (so every frame has to travel from the GPU’s dedicated memory over the system bus to the CPU and then to the screen rather than going directly from the GPU memory to the screen).
That means it can’t take advantage of adaptive refresh-rate technologies and it can negatively affect frame rates. So why not leave it on the GPU mode all the time? Because you’ll frequently get poorer CPU performance and even lesser graphics performance in games that balance CPU and GPU usage rather than going all-out on the GPU.
Nvidia launched the new generation of its Max-Q architecture, which introduced Advanced Optimus, in 2020. It’s smarter, with the integrated and discrete graphics sharing (rather than switching) the pipeline to the display, no reboot necessary. But Advanced Optimus needs a major change to system design, so laptops supporting Advanced Optimus still aren’t plentiful.
You can spot systems that require a reboot, both AMD- and Nvidia-equipped models, when they say they offer a MUX switch. That just means it’s more convenient than the next-step-down alternative, which is having to manually change it in the BIOS.
AMD’s current high-power laptop GPUs, the Radeon RX 6600M, 6700M and 6800M, don’t quite reach the level of the fastest Nvidia RTX models, but the 6800M has gotten pretty close, with performance on average falling between the RTX 3070 and 3080. AMD also launched its first line of S-series mobile GPUs, which require less power, and thus less cooling, for new thin-and-light gaming laptops like the 2022 ROG Zephyrus G14.
On the near horizon, Intel finally launched its first generation of Arc discrete high-performance GPUs, though we’ve yet to see any for the gaming laptops.
Does a gaming laptop’s CPU matter?
Yes, but not always. In general, sims benefit from faster clock speeds and more cores since those are required for the heavy calculations when worlds get complex. More and more AAA games are also starting to balance loads better between the CPU and GPU where possible as well. And if you bounce back and forth between a game and the rest of Windows, it can help speed that kind of multitasking a bit.
Still, a lot of games, especially first-person shooters, don’t take advantage of more than four cores. That was partly Intel’s rationalization for its continued reliance on its old 14-nanometer architecture for the 10th-gen high-performance (H series) processors. It let the company boost single-core clock frequencies, compared with gains it would have made by moving to a smaller process technology such as Ice Lake, which is designed to support more cores on less power draw.
Intel recently jumped to 10nm Alder Lake for its 12th-gen CPUs, which combines performance and power-efficient cores similar to Apple’s M1 chips. What we’ve seen thus far (like in the MSI Raider GE76) does show how fast the 12th-gen H-series CPUs can run and how it can help extend battery life.
What do I need to know about screen size and refresh rate?
And then there are the screens. All the major companies bumped their flagship 1080p configurations to 360Hz, but for many a gamer, they’re not essential: 240Hz max should be fine for those few times you can get frame rates above 240fps. Even 144Hz will do for many people, but artifacts like tearing, caused by the screen refresh rate becoming out of sync with the frame rate, depend on your games as much as your laptop brand and hardware.
We’re also seeing a lot more 120Hz 4K screens in the flagship models in both 17- and 15-inch sizes and a ton of 165Hz and 240Hz QHD (1440p) options. The latter are my favorites, balancing higher resolution — certainly enough on a laptop screen — with gaming-friendly refresh rates.
The review process for laptops, desktops, tablets and other computer-like devices consists of two parts: performance testing under controlled conditions in the CNET Labs and extensive hands-on use by our expert reviewers. This includes evaluating a device’s aesthetics, ergonomics and features. A final review verdict is a combination of both those objective and subjective judgments.
The list of benchmarking software we use changes over time as the devices we test evolve. The most important core tests we’re currently running on every compatible computer include: Primate Labs Geekbench 5, Cinebench R23, PCMark 10 and 3DMark Fire Strike Ultra.
A more detailed description of each benchmark and how we use it can be found in our How We Test Computers page.


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Accentus Medical Set for Further Growth
Published: Nov 09, 2010
Accentus Medical was awarded the grant in December 2009 in collaboration with Stanmore Implants Worldwide, an existing licensee and customer of Agluna® in the field of custom made limb salvage devices and patient specific joint replacements, and academic partner University College London. Following the successful development and clinical proof of concept of Agluna®, the principal objective of the grant project was to demonstrate commercial scale manufacture of the Agluna® technology.
Following the successful prototype demonstration project undertaken during 2010, and also the securing in August of a Licence and Services Agreement with Zimmer Holdings Inc., a global market leader in musculoskeletal care, the company is now set to benefit from growth and expansion of its manufacturing operations.
Philip Agg, Chief Executive of Accentus Medical, said: “The Technology Strategy Board grant has been crucial in demonstrating our ability to manufacture the Agluna® technology on a commercial scale. This capability will add to the company’s established manufacturing capability in supplying to global orthopaedic device customers its Acusure® range of plasma spray coatings for implant fixation.
“We now look forward to collaborating with both Stanmore Implants Worldwide and Zimmer in securing regulatory approval for products treated with the Agluna® technology in both the E.U. and U.S. The ability to demonstrate to commercial partners that we are able to meet the demand for commercial manufacturing represents a significant development for Accentus, enabling the company to compete on a global scale in the medical technology sector.”
Martin Pickford, Senior Vice-President of Business Development for Accentus Medical, added: “Having successfully developed the Agluna® technology, Accentus is now ready for full commercialisation, and this grant has enabled the company to successfully demonstrate commercial scale production capability. With a further pipeline of target medical device applications in development, the establishment of a manufacturing capability means that Accentus will be in a strong position to respond to future demand as we look to diversify the Agluna® technology into new sectors.”
Robin Wilson, Lead Technologist for High Value Manufacturing at Technology Strategy Board, said: “We are very pleased to see Accentus Medical benefiting from our financial support in developing a commercial scale manufacturing capability for the innovative Agluna® technology. We look forward to the future economic contribution that should result from the growth of this UK-based company operating in the high-value medical technology sector.”
For further information, please contact:
Tony Stephenson Accentus Medical T: +44 (0)20 7866 7864 M : +44 (0)7989 855113 Email: email@example.com
About Accentus Medical
Accentus Medical is a leading medical technology company that combines a long history of expertise in surface coating and modification technologies with dedicated research and development of new technologies for the medical device industry. With roots in the United Kingdom Atomic Energy Authority, and based at the historic Harwell Science and Innovation Campus, Accentus Medical has provided expertise in surface technologies to the orthopaedic device industry since the 1970s, serving major orthopaedic and medical device manufacturers worldwide.
The company works closely with industry partners to develop new surface technologies that address unmet market needs, and is renowned for its experienced staff and track record for responsive, high quality service. The services offered include hydroxyapatite and metal alloy coating (Acusure®) using a plasma spray process at Accentus Medical’s ISO 13485:2003 and ISO 9000:2000 accredited facility. Accentus Medical is also very well known for the medical device testing programmes offered by its in-house test laboratories. Manufacturers have been utilising test results provided by the company for many years as part of device homologation files all over the world.
For further information, please visit: www.accentus-medical.com
About Technology Strategy Board
The Technology Strategy Board is a business-led executive non-departmental public body, established by the government. Its role is to promote and support research into, and development and exploitation of, technology and innovation for the benefit of UK business, in order to increase economic growth and improve the quality of life. It is sponsored by the Department for Business, Innovation and Skills (BIS). For more information please visit www.innovateuk.org.
For further information, please visit: www.innovateuk.org


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The Calgary Housing Company has acquired East Village place, a 163-unit residential building located in East Village. This will come as a great relief for the residents of the tower who were living with uncertainty since the tower went into receivership last year.
The City of Calgary and Calgary Housing Company can now work together on plans for a community space within the two ground levels. Success will be a healthy operating model – one that will ensure the residential tower and other activities in the building meet the needs of the neighbourhood and are financially self-sustaining.
Engagement is being planned for this summer for The City to understand how community members would like to see the space used. This information will inform criteria to evaluate proposals from organizations interested in operating the community space.
The City will take the input from the community and assess ideas to make sure they are feasible. Once a clear set of criteria are in place The City will issue a call for proposals (RFP or EOI) for organizations who would be interested in providing community programming, that meets community need, in that space.
The City anticipates mid-2017 occupancy for program provider(s) in the community space. Until then, senior’s programming in the East Village will continue without disruption.
For more details on the announcement, please click here.
This content represents the personal views and opinions of the Ward Councillor and should not be taken as a statement of policy of The City of Calgary. The inclusion of any external content does not imply endorsement by The City of Calgary.

domain: news


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Davina Dalrymple, Countess of Stair
Scottish aristocrat and cousin of the Queen
ment to rural affairs was total. Among other community appointments, Lady Stair acted as Vice Lord Lieutenant.
The grounds of Castle Kennedy and the adjoining Lochinch Castle are famous for rhododendrons, magnolias and azaleas and have been described as one of the showpieces of Galloway. The gardens are situated on an isthmus between two natural lochs, the Black and the White, and provide a superb vista of the surrounding landscape.
The Stair family have been associated with the area since 1677. Lady Stair worked throughout her time as chatelaine to make the gardens horticulturally important, supervising the planting of many rare shrubs and trees. Since coming to Lochinch she has been part of the “gardening team” and remained much involved in the day-to-day running of the estate.
Lady Stair created a private garden which opens by arrangement to visitors in the summer. “I have lived in this lovely place for nearly 55 years,” she once said. “It has been very rewarding reviving several areas of the Castle Kennedy gardens which had become overgrown. I loved the challenge to develop the walled garden.”
Lady Stair created the magnificent walled garden, which had previously been the kitchen garden, with a dedicated zeal. It now complements the entire gardens and greatly enhances the general appearance of the grounds. The long panoramic views, the avenues of ancient trees and colourful terraces all fit naturally into the glorious Wigtownshire countryside. The setting and gardens reflect the more naturalistic landscape style which was made famous by the English landscape architect Capability Brown.
Another significant achievement was the Garden Centre at Castle Kennedy. Lady Stair not only introduced rare plants but ensured all the pot plants were of the highest quality – many from cuttings she herself had propagated.
The work Lady Stair has done over many years was recognised in 1985 when Lochinch was designated Heritage Status in recognition of its outstanding scenic, scientific, historic and architectural values.
She was a keen horsewoman with an interest in hunting. Lady Stair was master of the Wigtownshire Hunt in 1973 and a member of the Masters of Fox Hounds Association until 1991.
Another passion was carriage driving and Lady Stair had been a member of the Wigtownshire Driving Club since 1989.
Sue Munroe, its secretary, said: “She went to the South West Scotland Driving Trials often because she liked to compete at speed and at that time we were a non-competitive group. She also did the long-distance driving.”
Lady Beverley Vaux confirmed Lady Stair was an enthusiastic and first-class carriage rider. She told The Herald: “Davina was a very passionate horse lady.
“We schooled a pony for her called Sparky – she was Sparky by name and sparky by nature – and not at all easy to handle. Davina coped magnificently with her and often drove her at events. She was endlessly patient with Sparky and rarely had an accident.
“I did a lot of driving with Davina and she was always competitive, courageous, tremendous company and thoroughly charming.”
Her husband, the 13th Earl, died in 1996. She is survived by her three sons. The eldest, Jamie, is the 14th Earl of Stair.

domain: history


TUCSON, Ariz. (AP) — Tucson firefighters say a Mexican restaurant has suffered a fire just two months after its other location was closed due to similar circumstances.
Fire Capt. Barrett Baker says a fire crew arrived at Guadalajara Fiesta Grill on North Kolb Road shortly before 5 a.m. Saturday and found the building’s attic in flames.
Baker says additional crews had to assist in battling heavy smoke and flames.
Firefighters spent several hours extinguishing hot spots and the building is considered a total loss.
The building was unoccupied at the time and there were no injuries.
The cause of the fire is under investigation.
According to the restaurant’s Facebook page, the owners plan to rebuild.
The blaze comes two months after another Guadalajara Grill closed because of an early morning fire.
© 2014 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


Auckland council cleared of probe into V8 Pukekohe return
New Zealand’s Office of the Auditor-General has decided not to launch an investigation into the Auckland City Council’s handling of the pending return of V8 Supercars to Pukekohe.
As reported on voxy.co.nz the Auckland City Council’s process was within the Auckland Tourism, Events and Economic Development’s (ATEED) mandate and delegated financial authority.
The decision which will see V8 Supercars back at the historic Pukekohe circuit from next year with the organisers of the Australian Ford versus Holden series underwriting the event caused a public outcry.
CLICK HERE for the full story on Speedcafe.co.nz …


text:
The BYU football team held its annual spring scrimmage at LaVell Edwards Stadium on a rainy Saturday afternoon with around 6,000 Cougar fans in attendance.
The scrimmage started out with warmups and position drills, followed by 7-on-7 skeleton drills and finished up with two 11-on-11 scrimmages.
There were standout players on both sides of the ball, but freshman tight end Matt Bushman made the biggest impact.
“I’ve said it before, but Matt Bushman is a special player,” coach Kalani Sitake said. “He’s big and he’s smooth. He can do a lot of things.”
Bushman had four catches for 105 yards and two touchdowns in the scrimmage, and two catches for 22 yards and a touchdown in the skeleton drills. His highlight of the day came near the end of the scrimmage on a 65-yard catch-and-run down the sideline from freshman quarterback Kody Wilstead.
“I was just trying not to slip in the rainy condition and to catch the ball,” Bushman said. “Coach Detmer is telling the quarterbacks to look to the tight ends. We have had a lot of balls thrown to us and have a lot of reps. If we can have deep threats down the middle, it opens up all facets of the game.”
For junior quarterback Tanner Mangum, the pouring rain was a flashback to the Poinsettia Bowl game only a few months ago.
“It’s rained the last two games, but it is what it is—that’s football. You have to adjust,” Mangum said. “It makes it tough when the ball slips out of your hands and doesn’t come out as clean as you’d like. No excuse. You need to be able to play in any weather.”
Mangum went 7 for 9 for 101 yards in skeleton drills, and 10 for 16 for 102 yards and one touchdown in 11-on-11.
“It’s a night and day difference from last year to this year,” offensive coordinator and quarterback coach Ty Detmer said. “He’s seeing it, understanding it and lining guys up.”
However, Mangum threw three interceptions in the scrimmage and one in the skeleton drills.
“You know guys are starting to get comfortable when they get greedy and start to try to manufacture big plays,” Detmer said. “That tells me he understands what he’s looking at and trying to do just a little too much.”
Mangum agreed with the sentiments of his Heisman-winning coach.
“I think I was a little greedy,” Magnum said. “I wanted to come out and be able to push the ball down the field. And I think some of those throws went a little higher or shorter than I would have liked.”
Despite Detmer and Mangum’s downplaying of the three-interception performance, Sitake did voice some minor frustrations.
“He has a lot of confidence in his throwing ability, and our defense does a great job at taking away a lot of looks,” Sitake said. “I’m a little hard on Tanner because I expect him to be perfect every time. So, when he’s not, it’s a little disappointing to me.”
Detmer has not announced his back-up quarterback to Mangum yet, but sophomore quarterbacks Beau Hoge and Koy Detmer Jr. are battling it out for the position.
Hoge had the majority of the playing time in the skeleton drills going 10 for 14 for 78 yards and a touchdown, while Detmer Jr. went 6 for 6 for 93 yards.
“I feel like we’ve got two guys that can go in there and play, so that’s always good. You never know how many you’ll need each year,” Detmer said.
On defense, the Cougars were able to force a total of four interceptions, four sacks and two deflections.
“We have Fred Warner and Butch Pau’u lead the way,” Sitake said. “Those guys did a great job demanding more from the defensive guys.”
Pau’u and Chris Wilcox recorded interceptions in the scrimmage, while Isaiah Kaufusi had one interception during the skeleton drills and one in the scrimmage. Solomone Wolfgramm recorded a sack and a tackle for loss while Uriah Leiataua also tallied a sack and a deflection.
“(Ilaisa) Tuiaki has done a great job with the defense,” Sitake said. “Having (Ed) Lamb and (Jernaro) Gilford, those guys did a great job last year creating turnovers and making big plays.”
The Cougars finish up their spring practices next week, and then will break until fall camp starts up in August.


text:
Your Walls and Roof Can Be Living Green (3 videos)
Weíve shown you farms and vegetables gardens on the flat roofs of commercial buildings. Perhaps youíve thought ďif I ever build a new house Iíll look into it.Ē
You donít have to wait that long. You can put plants all over an upright wall, this is known as a vertical living wall garden. One idea is below and a second is on page 2. You can use any wall that gets sun; even the wall of a balcony on the 9th floor of your apartment building.
If you feel more ambitious, the residential green roof on page 3 will make your home cooler in the summer and warmer in the winter.
Build a Very Simple Vertical Living Wall Garden
This video shows you a very simple way to construct a green wall. All you need is a plastic unit that you buy, into which you pop lightweight soil and plants. There are a number of different units on the market; check out your local plant store or search online.
Watch this video and see how easy it is. The video shows ornamental plants, but you can also grow vegetables on this vertical garden.
The living green wall on page 2 is more of a DIY project.
Photo credit: spaceamoeba
DIY Wall Gardening
If you are more of a DIYer, you might build a unit like this one demonstrated by Dr. Sue Hamilton of the University of Tennessee Extension Service. Indoors you can use house plants to purify the air. Outdoors you can grow vegetables, save on water, and provide insulation for your house. Watch. Itís easy.
On page 3 see how to green any moderately sloping roof, making your home cooler in the summer and warmer in the winter.
Photo credit: jingdianjiaju
How to Turn Your Roof into a Green Roof
This video shows you how to add a planting bed to your roof, featuring a shed of the New England Wild Flower Society. You’ll need to have a strong moisture barrier, use lightweight materials for your soil, and have the right plants.
On this green roof they planted Northeastern plants on the sunny side, and Southeastern plants on the shady side. These are all plants that are used to dry and exposed conditions. The plants were watered once when they were planted, and haven’t been watered since. Looks doable, donít you think?
Photo Credit: pnwra


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Per 2 Cookies: 140 calories; 3 g sat fat (15% DV); 85 mg sodium (4% DV); 11 g total sugars. SmartLabel. Visit us at: facebook.com/chipsahoy. Call Weekdays: 1-800-622-4726. Try our other varieties! Chips Ahoy Cookies Original. Chips Ahoy Cookies Chunky. Made in Mexico.
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text:
Can Bogdanove draw Boom Boom forever, please? (X-Terminators #1)
I love this panel so very much.
(I also hope you guys cover that story in a later New Mutants annual where Bogdanove draws Boom Boom trying to find a boyfriend. That story is solid gold)
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New York Gov. Andrew Cuomo (D) looks to be facing another investigation.
New York Attorney General Letitia James (D) has opened an investigation focused on Cuomo's alleged use of state resources during the writing of a book he published about the COVID-19 pandemic last year, The New York Times reports. The attorney general had received a referral from New York's comptroller authorizing a criminal investigation.
This comes after the Times reported last month that staffers and aides for the New York governor worked on his book American Crisis: Leadership Lessons from the Covid-19 Pandemic. Cuomo, the Times wrote, reportedly relied on aides and staffers for "everything from full-scale edits to minor clerical work, potentially running afoul of state laws prohibiting use of public resources for personal gain."
Following this reporting, New York State Comptroller Thomas DiNapoli reportedly suggested there be an investigation examining "the drafting, editing, sale and promotion of the governor’s book and any related financial or business transactions." The governor has said that some staffers volunteered to help work on his book, but Cuomo adviser Richard Azzopardi told the Times that "every effort was made to ensure that no state resources were used in connection with this project."
Azzopardi also said Monday that "idea there was criminality involved here is patently absurd on its face and is just the furthering of a political pile-on."
Cuomo has already been facing an investigation focused his administration's handling of data on COVID-19 deaths in nursing homes, as well as an investigation into sexual harassment allegations against him. The governor has continued to resist calls to resign amid these scandals.


Gross domestic product expanded at a 2.8pc annual pace in the fourth quarter, the Commerce Department said on Friday.
While stronger than the 1.8pc recorded in the third quarter, and the best showing since early 2010, it fell short of the 3pc most forecasters had expected.
Those expectations were built around more robust spending by US consumers, who still account for more than two-thirds of GDP. Spending rose 2pc, an improvement on the third quarter, but it trailed expectations of 2.4pc.
"The headline GDP increase was the best of 2011, but long-standing headwinds were still frustratingly evident," said Chris Low, an economist at FTN Financial.
The figures also help explain why Federal Reserve chairman Ben Bernanke put the accent on the hurdles the recovery still faces at his press conference this week. Mr Bernanke said that he's not ready to declare the recovery had entered a "new, stronger phrase" despite the recent improvement in data.
"The economy is in better shape than we could have hoped for," US Treasury Secretary Timothy Geithner insisted at the World Economic Forum in Davos yesterday. He added that he expects the economy to grow between 2pc and 3pc this year.
Fourth-quarter growth also received an unexpectedly large lift as companies and factories increased their stockpile of goods at a much faster pace than expected. The boost, which amounted to 1.9 percentage points, is not expected to be repeated in the current quarter.
This is a "less favourable report than people will have been looking for," said David Semmens, an economist at Standard Chartered. "This report only reinforces the 0.8pc (growth) that we look for in" the first quarter, he said.
Despite ambitions to move the US economy away from a reliance on the consumer, the current recovery remains highly dependent on their spending.
For 2011, the world's biggest economy grew 1.7pc, down from 3pc in 2010.


Address: W. 55th St. btw. 6th & 7th Aves. - 212-581-1212
Description: For ten exhilarating days each year, feel the rush...the exuberance...the sheer joy that is dance, from New York City, across the country, and around the globe! Experience the world-famous alongside the cutting-edge, treasured favorites surrounded by undiscovered gems. Multiple companies appear in each performance, offering audiences a sampling of the best that dance has to offer - from hip hop to ballet, tango to tap, and so much more. So bring your family, grab your friends, join us and fall in love...Fall for Dance! 2010 Fall for Dance festival September 28 - October 8. Check back soon for full programming! Tickets On Sale September 12 at 11AM.


Powerful new rush of buyers sends housing prices soaring
residential real estate experts are reporting a powerful new wave of buyers, increasing the demand on an already low housing inventory throughout Miami-Dade County.
While no one has a crystal ball to know exactly how long the strong demand will last, in the next three to five months more properties will start to come on the market and will affect the pricing, according to Ivory Cooks, a realtor at Coldwell Banker Realty and Master Brokers Forum’s advisory board member.
“As more competition comes on, we should start to see more competitive pricing and this should open the market for more buyers,” he said.
Specifically, in Coconut Grove, Mr. Cooks said there are a few reasons why more properties will come on the market soon. One, some sellers are now more comfortable with putting their homes on the market because they know more people are getting vaccinated, and two, some sellers are riding the wave and they see how high the prices have gotten and they want to take advantage of it.
“They also feel that no one knows how long this will last and they would rather get their money now,” he said.
The Coconut Grove neighborhood market is extremely strong as demand in both condos and single-family homes continues to rise, Mr. Cooks said.
“Condos and single-family homes are selling at 97% of the contract price,” he said. “In April 2021, the average days on the market for condos was 56 days and for single-family homes 119 days.”
Mr. Cooks said he sees the prices in the Coconut Grove market continuing to rise also due to the increasing number of people moving into Miami-Dade from California, New York and Texas.
“It is really difficult to predict the pricing market two or three years from now, but I think the rise in prices will continue but will probably start to slow down in the next few months,” he said.
A 2021 Homebuyer Insights Report from Bank of America found that across all generations, individuals are looking for a sense of connectedness and belonging when it comes to where they live. About 51% of younger generations – those ages 18 to 43 – and nearly 32% of older generations – ages 57 to 75 – say the community has become more important. Homeownership has long encouraged residents to connect with neighbors, build a community and put down long-term roots that give homeowners more reason to become involved in their neighborhoods.
A huge influx of buyers who have been renting for a really long time are trying to now achieve homeownership, said Vincent Viscomi, vice president and area lending manager for Bank of America.
“Low housing inventory and interest rates are in part driving today’s competitive market,” he said. “Interest rates are still at historic lows where you can still buy and be approved below 3% sometimes depending on the property.”
For buyers ready to start their homebuying journey, Bank of America continues to offer its Digital Mortgage Experience, which allows buyers to secure preapproval online so they can begin the house hunt with a competitive edge. Also, the bank’s real estate center page provides a simple way to research neighborhoods, shop for homes and identify properties that may be eligible for the bank’s homebuyer grants, Mr. Viscomi added.
The powerful new wave of domestic buyers, purchasing more expensive primary residences and second homes with longer stays, is a direct result of the pandemic catapulting the remote working trend, tax reform creating tax refugees, Florida’s no state income tax, the influx of technology and finance companies, and “the awesome quality of life here and the enhanced buying power because of low-interest rates,” said Ralph De Martino, broker and president of Ocean International Realty and Master Brokers Forum’s board member.
Comparing January through April of this year to 2020, the statistics show that huge amounts of money are pouring into Miami real estate, he said.
Looking specifically at the Miami Beach condominium market, in 2020 there were 504 closed sales at a median price of $349,700. Fast forward to 2021, there were 1,122 sales with a median price of $525,000, Mr. De Martino said. “That’s a median price increase of 50% – keep in mind that median is the price in the middle, with half of the sales sold for less and half for more. It is not the amount any particular property appreciated, and the number of sales increased by 123%.”
Miami Beach single-family homes saw 61 closed sales in the same period of 2020 at a median price of $1,925,000. So far this year, 245 homes have sold with a median price of $2,390,000, marking a 24% increase and 302% increase in closed sales, according to Mr. De Martino.
“The average price is less of an indication of price movement, but it reflects the fact that more expensive properties are selling,” he added.
The condominium 2020 average sale price was $695,693 compared to 2021’s $1,351,555, which is 94% higher and 332% more money being spent, Mr. De Martino said. In the single-family market, the 2020 average was $3,132,162 compared to $4,983,939 in 2021 – a 59% increase and a 539% increase of dollars being spent.
“My prediction is that looking forward, because of the consensus that this new wave of interest will continue, the market will continue to see substantial upward pricing pressure but not at a sustained rate of this year’s numbers.”


text:
By Jacob Lindelöw Berntson
Over the last few years, Mozambique has once again seen fighting between the two groups that were the main actors in the Mozambican Civil War 1977-1992. This war left more than one million people dead and several millions internally displaced or forced to flee to neighbouring countries. An astonishing fact is also that first in September this year Mozambique declared itself free from landmines, left in the ground since the civil war and the independence struggle with the Portuguese colonial power. With these horrific statistics in mind, and considering the relative success and prosperity Mozambique has experienced over the last few years, what makes the old enemies unable to bury the hatch?
The two groups in question are Frelimo (Mozambican Liberation Front) and Renamo (Mozambican National Resistance).
The first one, Frelimo, was founded during the colonial days and was the organisation that brought independence to Mozambique. Its leader, Samora Machel, was an ardent anti-colonialist who made many influential friends in the anti-colonialist camp during the 1960s and 70s, including Swedish Prime Minister Olof Palme and Algerian strongman Houari Boumediene. After independence, Machel nationalized schools and hospitals and declared Frelimo a Marxist-Leninist party. Frelimo has been in power ever since independence, with current President Filipe Nyusi being the party’s, and Mozambique’s, fourth president.
Renamo, on their part, was founded in 1975 as a Rhodesian initiative to fight Frelimo, who were accommodating Zimbabwean independence fighters. Taking an anti-communist stance, the group had backing from apartheid South Africa as well as the CIA. Their current leader, Afonso Dhlakama, has been the leader of Renamo since 1979.
The Mozambican Civil War in brief
It is important to note that the Mozambican civil war took place in a complex regional and international cold war context. Therefore, it would be wrong to claim that Renamo necessarily had an apartheid or Western agenda when they commenced their insurgency against Frelimo in 1977. Rather, they gained support from apartheid South Africa and the CIA due to the latters’ fears of another former Western colony turning into a Soviet ally. Moreover, Samora Machel housed several ANC members in Mozambique, which led to the apartheid regime supporting Machel’s enemies, and subsequently military intervening in Mozambique.
Over the course of the war, Renamo launched a guerilla struggle, but were unable to make significant gains. Both sides committed war crimes and forced parts of the population into joining their camp, making civilians paying the price for the regional power struggle. After a military stalemate in the 1980s, the parties eventually started negotiating, and in 1992 a peace agreement was achieved. In 1994, Mozambqiue held its first multi-party elections.
One of the concessions made by the Frelimo government in the 1992 peace accords was that Renamo was to be allowed to keep some of its forces. They may have regretted that decision now, as another Renamo insurgency has been underway since 2012.
This did, of course, not happen in a vacuum. The Frelimo government, which is seen as omnipresent in Mozambique, has several times been accused of rigging elections and does de facto control the Mozambican judiciary. Renamo decided to take up arms as a protest against the government’s failure to bring about reform in electoral legislation and the refusal to integrate Renamo’s forces into the army and police force. For Renamo, this would be seen as a step to give them greater power, whereas the Frelimo government has been reluctant as they fear a coup from within. This resulted in clashes and Renamo attacks on government and military buildings, with the government responding with killing senior Renamo members as a counterattack.
A peace deal reached between Renamo leader Afonso Dhlakama and former president Armando Guebuza in the summer of 2014 meant that elections could be held later that year. The elections saw yet another Frelimo victory, seeing current President Filipe Nyusi taking over from Guebuza. However, also this election was tainted by allegations of fraud, with Dhlakama leading the charge on the allegations, despite African election monitors having judged the elections as largely free and democratic.
However, Renamo did not stop at allegations. After winning a majority in the Sofala, Manica, Tete, Nampula and Zambezia provinces, Renamo demanded autonomy in these areas. Renamo also insisted on the full 2014 peace agreement being implemented and heavily opposed the government’s decision to dissolve EMOCHIM, a foreign body aimed to ensure the cessation of armed violence and respect of the cease-fire agreement. This decision was taken without Renamo’s consent, which in turn angered many oppositional figures. The last drop for Renamo came in April 2015, when the government rejected their demand of autonomy in the five provinces, claiming it was unconstitutional. Soon after, Renamo set up their own military headquarter, stating that they would themselves take charge on implementing their autonomy over the provinces they won.
From bad to worse
This move did not force the government to make concessions. Rather, Frelimo have themselves started to adopt a more bellicose rhetoric and strategy. In September this year, Renamo leader Afonso Dhlakama and his convoy was attacked on two separate occasions by a group of men believed part of Mozambique’s paramilitary police force, with the second attack developing into an armed stand-off claiming 20 lives on each side. On 9 October, Dhlakama’s house in Beira was surrounded by police, and Dhlakama eventually put in house arrest, bringing back Renamo’s fears that Frelimo wants to impose a one-party state to life.
It is believed that a hard-line faction within Frelimo is responsible for ordering these attacks. This group is said to be unhappy with President’s Nyusi too reconciliatory attitude towards Renamo, and is therefore attempting to sabotage the negotiations by attacking Dhlakama. The G-40, Frelimo’s propaganda unit (not a hiphop collective), has in some outlets propagated for the so called “Sovimbi solution”, meaning that the government should, just like the Angolan army did with rebel leader Jonas Sovimbi, assassinate Dhlakama.
Some people actually thought that was what had happened to Dhlakama, as he hadn’t been seen since he was placed in house arrest in October. Then, all of a sudden, he showed up again a few days ago, stating that Renamo will take over the north of the country in March, and that Renamo could disarm Frelimo, if they so wished, in less than a day.
We have yet to see how President Nyusi, and especially the radical fringes within Frelimo, will deal with Dhlakama’s latest statement. Nyusi has shown promising signs of wanting to create peace, but is perhaps too tied down to a party that was heavily involved in fighting the same group they now, once again, have to make peace with.
Even though most people don’t believe another civil war will take place, even a political crisis is something that Mozambique simply cannot afford. Avoiding a crisis and further violence is going to demand strong and responsible leadership from both sides, and will be the ultimate sign indicating if Frelimo and Renamo are finally ready to re-define their hostile relationship.
Photo above by Voice of America [Public domain], via Wikimedia Commons


Nothing but problems
By diesel580 on
Vehicle1999 Dodge Intrepid ES 4dr Sedan
ReviewI have a 99 Intrepid with 65k miles.
I've had nothing but problems with this
vehichle. So far I've had 2 window
motors replaced and a clamp bite
through a hose causing an oil leak.
This car loves to warp rotors. Now
I've shelled out $1,400 to have a new
Rack and pinion replaced and I still
have problems related to steering.
Don't look to Dodge to stand by their
statement of "dependability". If this
is the new Dodge, I think this will be
my last Dodge.
Best FeaturesStereo system.
Worst FeaturesLonger warrenty. Improve the rotors so they aren't so prone to warpage.
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text: WILTON -- The Board of Education and Board of Finance got together to talk about the proposed schools budget Monday night, but the discussion ended up focusing on state education mandates. As it stands, the Board of Finance and the Board of Education have quite a gap to bridge. Superintendent Gary Richards requested a 4.82 percent budget increase from 2013-14 and the Board of Education approved a 4.52 percent increase. The Board of Finance wants the schools and town to come in with an increase no greater than 1.75 percent. While the Board of Finance started the meeting poking at the schools budget, quizzing the board members and administrators on things like increases in conference fees and technology, the conversation quickly turned to mandates. New Board of Finance member Richard Creeth asked the board how they could better control costs moving forward. He said the board's future projections, all in the 4 percent to 5 percent range, are "not sustainable." "My question to everybody else in this room, is what are the plans for dealing with \u2026 this trend in the long-term, more than a year or two out?" said Creeth. "Clearly it's unsustainable, or else, we'll change Wilton and the only people living here will be the people who can afford Westchester-level property taxes." Board of Education Chairman Bruce Likly put the blame on Hartford and education mandates. "We're trying to keep our employment costs as close to that as we can, but we can't fight those other pieces," Likly said of the mandates. "Eventually our ability to move gets taken away from us. Personally, I see that as the biggest issue." Mandates have been popular refrain for the school district when talking about its budget. During a public hearing in January, Richards said the majority of his proposed increase was contractually obligated or state-mandated, including considerable special education increases. Only small bits of it, like two new security staffers, were new additions. "I feel at times we're shoveling sand against the tide, because more and more comes at us," said Likely, who told the Board of Finance cuts would come from student services. "I think this board is getting pretty tired of what Hartford is doing to us. It's making it hard for us to react and deliver the best education possible." The schools representatives put some hope in the General Assembly's Mandate Relief Task Force, which state Rep. Gail Lavielle, R-143, sits on, but Richards admitted there is no indication on how successful they could be at removing educational red tape. At one point, Likly even joked about Wilton just not complying with the state mandates. Board of Finance Chairman Warren Serenbetz commended the work the school board did at the end of the meeting, but after the meeting downplayed the significance of the mandate talk. "To be fair, it's the same story, really, every year. You've got to teach kids and that requires money, because you have to pay the teachers. Then you have this growing pool of needs for special education," he said. "It's not a lot of new stuff."

domain: economics


text:
Gareth Porter: U.S. Special Operations Forces (SOF) killed well over 1,500 civilians in night raids in less than 10 months in 2010 and early 2011, analysis of official statistics on the raids released by the U.S.-NATO command reveals.
Berry Craig: With Wisconsin Governor Walker’s blessing, Republican lawmakers are ramming home a bill that requires voters to show photo ID at the polls. Of course, the idea is to decrease the Democratic vote.
Leonard Isenberg: At the root of public education’s generational failure to educate Latino and Black students in this country is the unrelenting not so subliminal message that these young people are inferior and cannot learn.
Treva Brandon Scharf: Everyone should exercise their right to bare arms – just not in the state of Georgia though, where every Second Amendment nut job feels the need to show off their guns everywhere they go.
Elizabeth Nussbaumer: Offsets and the added profit from repurposed pollution perpetuate and further engrain the trend of polluting with impunity by using energy sources that only take us backwards in our need to address growing pollution debts.


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As a National Clinic Trials Network Lead Academic Participating Site, we hope to accomplish the following: 1. To provide scientific leadership and intellectual input in the creation of thoughtful, feasible trials to improve the health of cancer patients. We will accomplish this aim through the ongoing participation in clinical trials that spn the spectrum of disease-specific and radiation and surgical oncology;by applying the UNC culture of multidisciplinary care to make NCTN trials stronger and more modern;by leveraging the commitment of junior faculty, who will be the leaders of tomorrow; and by applying health services research in the development of clinical trials, including factors important to clinical outcomes, such as cost effectiveness, delivery of care, and policy. 2. To continue to be strong supporters of Network trials, through our rapidly growing clinical enterprise and robust accrual. We will support this aim by building on our historically strong accrual to CALGB, GOG, and ACOSOG trials and our well-funded and organized infrastructure, and through active participation across the NCTN. 3. To provide opportunities for excellent translational science embedded in NCTN clinical trials. UNC has a long commitment to translational science and has served as reference lab across multiple trials, with substantial (more than $3 million) investment in Next Generation sequencing and genomics;we are well suited to serve as a translational research collaborator for clinical trials in the future.
The UNC Lineberger Lead Academic Participating Site brings together an accomplished group of academic clinical oncologists and faculty from related disciplines, organized into multidisciplinary disease-site groups, to undertake cutting edge clinical research across the spectrum of cancers. The UNC LAPS will commit the staff and professional resources to manage and evaluate these research activities, accrue patients, and share knowledge with the wider research community. This effort will serve to enhance the understanding of cancer progression and treatment, lead to new studies based on information learned, and improve outcomes for patients.
|Camargo, M Constanza; Bowlby, Reanne; Chu, Andy et al. (2016) Validation and calibration of next-generation sequencing to identify Epstein-Barr virus-positive gastric cancer in The Cancer Genome Atlas. Gastric Cancer 19:676-81|
|Becker, Marc A; Ibrahim, Yasir H; Oh, Annabell S et al. (2016) Insulin Receptor Substrate Adaptor Proteins Mediate Prognostic Gene Expression Profiles in Breast Cancer. PLoS One 11:e0150564|
|Basch, Ethan; Rogak, Lauren J; Dueck, Amylou C (2016) Methods for Implementing and Reporting Patient-reported Outcome (PRO) Measures of Symptomatic Adverse Events in Cancer Clinical Trials. Clin Ther 38:821-30|
|Hatch, Ace J; Sibley, Alexander B; Starr, Mark D et al. (2016) Blood-based markers of efficacy and resistance to cetuximab treatment in metastatic colorectal cancer: results from CALGB 80203 (Alliance). Cancer Med 5:2249-60|
|Freedman, Rachel A; Seisler, D K; Foster, J C et al. (2016) Risk of acute myeloid leukemia and myelodysplastic syndrome among older women receiving anthracycline-based adjuvant chemotherapy for breast cancer on Modern Cooperative Group Trials (Alliance A151511). Breast Cancer Res Treat :|
|Brooks, Samira A; Khandani, Amir H; Fielding, Julia R et al. (2016) Alternate Metabolic Programs Define Regional Variation of Relevant Biological Features in Renal Cell Carcinoma Progression. Clin Cancer Res 22:2950-9|
|Atkinson, Thomas M; Ryan, Sean J; Bennett, Antonia V et al. (2016) The association between clinician-based common terminology criteria for adverse events (CTCAE) and patient-reported outcomes (PRO): a systematic review. Support Care Cancer 24:3669-76|
|Abida, Wassim; Milowsky, Matthew I; Ostrovnaya, Irina et al. (2016) Phase I Study of Everolimus in Combination with Gemcitabine and Split-Dose Cisplatin in Advanced Urothelial Carcinoma. Bladder Cancer 2:111-117|
|Dickler, Maura N; Barry, William T; Cirrincione, Constance T et al. (2016) Phase III Trial Evaluating Letrozole As First-Line Endocrine Therapy With or Without Bevacizumab for the Treatment of Postmenopausal Women With Hormone Receptor-Positive Advanced-Stage Breast Cancer: CALGB 40503 (Alliance). J Clin Oncol 34:2602-9|
|Jatoi, Aminah; Muss, Hyman; Allred, Jake B et al. (2016) Social support and its implications in older, early-stage breast cancer patients in CALGB 49907 (Alliance A171301). Psychooncology 25:441-6|
Showing the most recent 10 out of 52 publications


ITSPs, PBX (News - Alert) vendors and calling card providers now have a range of White Label SIP branded softphones, recently released from SessionTalk, a UK based developer.
The company has released three selections such as Basic, Advanced and Premium. The Basic package is ideal for startup VoIP providers and Calling Card providers, whereas the Advanced and Premium packages is suitable for PBX vendors and ITSPs looking for business features such as call transfer, call conferencing and call encryption.
The branded products will be based on the SessionTalk Softphone for iPhone and SessionTalk Softphone for Android products available on the iTunes and Google Play stores.SessionTalk Android (News - Alert) Edition makes VoIP easy for the beginner user with its preconfigured SIP accounts and intuitive user interface. This edition has enterprise features for the business user such as Call Transfer, Call conferencing and a flexible Dial Plan.
SessionTalk iPhone Edition is a standalone SIP Phone (News - Alert) and has a highly intuitive iPhone like interface for call management which iPhone users will be very familiar with.The company plans to charge $2000 USD per platform for the Basic option through to $4000 USD per platform for the Premium version.
SessionTalk Ltd is a mobile software development company, based in the North West of the United Kingdom. The company develops custom SIP applications and softphones for clients worldwide. In addition, the company has a track record of developing Enterprise VoIP and Social Networking applications for major telecommunications operators.
The company plans to release the Blackberry 10 version of the SessionTalk Softphone as well as SIP VoIP SDKs for both iOS and Android later this year.
Edited by Maurice Nagle


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What does angiogenesis mean and how does is it relate to cancer?
Cancer biologist Robert Benezra explains angiogenesis, the process by which new blood vessels form, and how it relates to cancer research. Angiogenesis is the process by which new blood vessels form, allowing the delivery of oxygen and nutrients to the body’s tissues.
How do anti angiogenic drugs work?
Researchers developed drugs called angiogenesis inhibitors, or anti-angiogenic therapy, to disrupt the growth process. These drugs search out and bind themselves to VEGF molecules, which prohibits them from activating receptors on endothelial cells inside blood vessels. Bevacizumab (Avastin®) works in this manner.
What is the importance of angiogenesis to tumor formation What factor regulates this in cancer cells?
Angiogenesis is stimulated when tumor tissues require nutrients and oxygen. Angiogenesis is regulated by both activator and inhibitor molecules. However, up-regulation of the activity of angiogenic factors is itself not sufficient for angiogenesis of the neoplasm.
What triggers angiogenesis?
The mechanism of blood vessel formation by angiogenesis is initiated by the spontaneous dividing of tumor cells due to a mutation. Angiogenic stimulators are then released by the tumor cells. These then travel to already established, nearby blood vessels and activates their endothelial cell receptors.
How do you stop angiogenesis naturally?
“Many of the compounds that have been found to have anti-angiogenic activity are found in plants,” she says. “A well-balanced diet consists of a variety of plant-based foods—particularly dark green leafy vegetables, fruits, nuts, seeds, and legumes—as well as fish and other lean protein.”
What foods are anti-angiogenic?
Anti-angiogenic food include vegetables such as purple potatoes, carrots and leeks. Bero explained to WLBT that her diet also included berries, walnuts, green tea and herbs, such as garlic.
How do you stop angiogenesis?
Approved angiogenesis inhibitors include:
- Axitinib (Inlyta®)
- Bevacizumab (Avastin®)
- Cabozantinib (Cometriq®)
- Everolimus (Afinitor®)
- Lenalidomide (Revlimid®)
- Lenvatinib mesylate (Lenvima®)
- Pazopanib (Votrient®)
- Ramucirumab (Cyramza®)
What are the 3 ways cancer can spread?
There are three primary ways tumors can spread to distant organs:
- Through the circulatory (blood) system (hematogenous)
- Through the lymphatic system.
- Through the body wall into the abdominal and chest cavities (transcoelomic).
How does angiogenesis contribute to metastasis?
Angiogenesis, the recruitment of new blood vessels, is an essential component of the metastatic pathway. These vessels provide the principal route by which tumor cells exit the primary tumor site and enter the circulation.
How do cancer cells induce angiogenesis?
Tumor angiogenesis actually starts with tumor cells releasing molecules that send signals to surrounding normal host tissue. This signaling activates certain genes in the host tissue that, in turn, make proteins to encourage growth of new blood vessels.

domain: medical


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Great service. Everybody we met were enjoyable. Very clean modern room. We can't tell it is a renovated hotel. We first thought it was brand new. It is somewhat rare in Cape Cod. Pools are large and clean. We were a bit afraid of the noise because it is close to the airport but we were positively surprised how quiet it was. We enjoyed the fireplace outside, what a great idea! No hesitation to recommend it.
- Reservation Options:
- TripAdvisor is proud to partner with Booking.com, Hotels.com, Expedia, Odigeo, TripOnline SA, Hilton Hotels Direct, Travel Republic (UK), Ebookers, Evoline ltd, HotelsClick, 5viajes2012 S.L., Cancelon and getaroom.com so you can book your DoubleTree by Hilton Cape Cod - Hyannis reservations with confidence. We help millions of travellers each month to find the perfect hotel for both holiday and business trips, always with the best discounts and special offers.
- Also Known As:
- DoubleTree By Hilton Cape Cod - Hyannis

domain: travel


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They Lived in Headingley
Who was Elinor Lupton?
The surname ‘Lupton’ is familiar to many in Leeds: in Headingley, we have Lupton Flats, and there’s a Lupton Avenue and a Lupton Street in other parts of the city, the University had its Lupton Hall and in 1952 Agnes and Norman Lupton gave a valuable collection of watercolours and drawings to the City Art Gallery. Locally many are now concerned about the future of the Elinor Lupton Centre (formerly the Christian Science Church) on Headingley Lane which Leeds Girls High School has placed on the market.
The Luptons were one of the prominent families in 19th century Leeds: William Lupton and Co. was the town’s oldest woollen business and Dibb Luptons was a leading legal firm. Three Luptons were mayors, others served as aldermen and councillors and played important roles in the town’s flourishing voluntary organisations. Even as early as the middle of the century, Lupton ladies were beginning to take part in public life, in the anti-slavery movement and organisations to promote women’s education.
This is the world into which Elinor Gertrude Lupton was born in 1886. Her father, Arthur ran the family woollen business but she never really knew her mother who died in 1888 giving birth to her sister, Elizabeth (Bessie). Their father never re-married and his four children were brought up by a series of nursemaids and governesses. in the family home, Springwood, off Oakwood Lane .
Arthur introduced his two daughters to charity work at an early age. Their grandmother had founded the Leeds Ladies Association for the Care and Protection of Homeless Girls and Elinor and Bessie were encouraged to save their pocket money to make gifts to the charity. Aged eight, Elinor was sent to boarding school in Southwold, and in 1905 she went on to read classics at Newham College, Cambridge. To us it seems surprising that following her graduation in 1908, she returned to Springwood to keep house for her father. It isn’t clear whether this was to be her life’s work, or merely an interlude before she settling down to married life.
The First World War which was to transform so many people’s lives, for Elinor presented both a loss and an opportunity. The names of seven Lupton sons are commemorated on the war memorial at Mill Hill Chapel and the deaths of a generation of young men meant that six of the Lupton daughters never married.
At the beginning of war Elinor trained as nurse and worked in military hospitals in France and Belgium. After the War, it was this experience that led to her being appointed the first lady member of the Board of the Leeds Infirmary; she remained a member of the governing body for the next forty years eventually becoming its chairman. She still kept house for her father who in 1920 sold Springwood and moved into the main Lupton residence, Beechwood on Elmete Lane. For a time, she also worked in the family woollen business but whether through inclination or the loss of the opportunity to marry, Elinor’s future life was to be devoted to public service.
The pattern of her involvement in public life was shaped by kinship ties: members of the Lupton family had long been involved in the management of the Infirmary and her grandfather had been active in the founding of the Yorkshire College. When the college became a university in 1904 her father was appointed the first Pro-Chancellor. It’s not then surprising that Elinor also became involved in university affairs, serving as the Chairman of the Women’s Halls Committee and generously donating money to university projects. In 1937, she was appointed a JP and in 1942 became Lady Mayoress to Leeds’ first woman Lord Mayor, her friend, Beatrice Kitson. ‘We were the two worst dressed women in Leeds’ was Elinor’s somewhat dry comment on the experience.
But why did Leeds Girls High School name their annex on Headingley Lane after Elinor? She first joined the school’s governing body in 1915 and retired as a governor in 1969 having served as Vice-Chairman between 1926-36 and then as Chairman until 1957. Again there were family connections, in 1876 her grandmother had been a member of the committee which set up the joint stock company that established the High School. Elinor’s generosity to the school was legendary. For example, in 1939 when the school’s finances were in a critical condition, she guaranteed a bank overdraft and in 1945, she donated £12,000 to establish a trust fund. She remained a trustee of the fund until her death in 1979. Sixty-four years of service and many bequests to the High School were commemorated when the school decided to call their new arts building, the Elinor Lupton Centre.

domain: library


This Week in Kpop is iKONic, In fact, iKON really laid waste to the week and did so alone, while you were snug tightly in your new Christmas blanket. We can't be more excited that the holiday season is over and Kpop has been released from the stranglehold of Christmas, so let's get started already!
iKON rules December
How appropriate is it that iKON's coming back to town, taking names, checking them Twice, etc? For months, we've debated iKON's debut and seven big releases in now, there's no mistaking it: iKON will be a dominant group. They're also one of the busiest - with a full album out and more videos in 2015 this side of Jay Park, they've entrenched themselves in the Kpop sphere. Releasing "What's Wrong?" and "Dumb and Dumber" in a notoriously vacant holiday season is a smart move, and what's even better is that both of these songs are lively jams.
They're also both showing more hyper energy and mucho personality that we think will define iKON far more than they're mellow and, if we're going to be honest, forgettable "My Type." We say that in the face of that song being an indisputable hit and their future already secured.
"What's Wrong?" is a strange beast and we're loving it as a party anthem, as the video degenerates from a confrontation with masked women, to dodge ball, and then, of course, to dancing. But the real gem may just be "Dumb and Dumber." Some are calling it iKON's "Fantastic Baby," and maybe it does have similarities, but we think "Dumb and Dumber" stands on it's own. It's fun, it's ecstatic, and iKON seems to be really letting loose and showing the urgency of jamming out that was missing in their earlier releases. We're not saying that all of iKON's songs need to be energetic and caustic, but to stand out in the crowded boy band field, it certainly helps to make a scene.
Check this videos out, friends. iKON has saved December!
Christmas is Over. OR IS IT?
Our long musical nightmare is just about over. We think. We hope. Christmas is over and with the coming of the new year, we're pumped for, we're sure, a slew of new releases. We'll never understand why Christmas is so big and Kpop and how nearly every idol needs to have their own swing at the holiday, usually in the cheesiest way possible. It's over. But for some of us, the threat of Christmas is alive all year long, forever.
We liked "Hide and Seek" though by Turbo. KJK is always great to see and hear, friends.
Critical Kpop Podcast - Episode 17: Our Least Favorite Things
To keep proving that we are the biggest Scrooges of Kpop, we took a look at some of our least favorite parts of Kpop, and the picture above may just give all the hints you need here. Tim and Zander take a look at a host of Kpop issues, which you can listen to right here.
December 20-26, 2015
And that was This Week in Kpop! The holidays are over and we're ready to get 2016 started already! We're super excited for the new year and what our favorite idols will bring. Aren't you ready? Well, get ready, already. Until next time, have fun and be safe!


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|treatment of pneumonia in cats||1.88||0.5||6687||15|
|treatment of pneumonia in cattle||0.15||0.4||9892||85|
|treatment for pneumonia in cats||1.7||0.7||1977||72|
|pneumonia treatment in cats||0.81||0.6||9661||64|
|pneumonia in cats treatment medication||0.42||0.9||1216||83|
|aspiration pneumonia in cats treatment||0.98||0.8||5588||92|
|treatment of drenching pneumonia in cattle||1.7||0.6||2397||33|
|treatment for pneumonia in cattle||1.9||0.6||2604||16|
|pneumonia in cattle treatment||1.09||0.4||3641||28|
|mycoplasma pneumonia in cattle treatment||0.1||0.7||9767||52|
|best treatment for pneumonia in cattle||1.27||0.8||749||50|
Selection is based on bacterial culture and sensitivity. Mycotic (fungal) pneumonia typically requires long-term (2+ months) with systemic anti-fungal medication. Supportive care such as a nebuliser or oxygen therapy if the cat is experiencing breathing difficulty. Fluid therapy to correct dehydration.What are the signs of pneumonia in cats?
Symptoms include fever, coughing, runny nose, labored or loud breathing, and a lack of appetite. If your cat comes down with pneumonia, medications to treat the underlying cause and supportive care are usually recommended. Keeping your cat current on vaccinations and in general good health is the best prevention for this disease.What is the best medication for pneumonia?
An antibiotic such as amoxicillin is prescribed when pneumonia is suspected. Once pneumonia is diagnosed, it's best to start treatment within four hours. Infection with a germ (bacterial infection) is a common cause and antibiotics kill bacteria. Amoxicillin is usually effective against the most common causes.


BOSTON (WBZ-AM) -- Rob Gronkowski's wishy-washy answer about coming back next season has fans worried--and has sparked reports that Gronk may be considering leaving the NFL for a film career.
Boston Sports Journal editor Greg Bedard told WBZ NewsRadio 1030's Adam Kaufman that he could see it happening.
"We have seen over the past couple of years Rob dip his toe into the Hollywood, TV waters as part of Gronk, Inc.," he said. "I think that they have seen that the water is warm and comfortable, and it's a lot of money and you don't get beaten up."
Gronkowski has a long history of injuries with New England--and Bedard says it may not be worth the pay anymore for him.
"I think we're headed for a showdown between the Patriots and Gronkowski where the Gronk camp says, look, Rob can go make x-amount of money in Hollywood, in movies, TV, whatever, everybody loves Gronk," he said. "It's either you make it worth his while as far as being the top-paid tight end in the NFL--which he is far from at this point in terms of guaranteed money--or, we're going to go there. Because nobody's diving for his knees in Hollywood, so why would he risk it for $8-9 million a year in football?"
Listen to Kaufman and Bedard below: