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A hiring bidding war broke out among a half-dozen of the Boston area’s top executives last week — but it will be about a decade before the job candidate they were all clamoring for is old enough to report to the office.
The object of their corporate desire was 11-year-old Maxwell Surprenant , a fifth-grader at St. Joseph Elementary School in Needham.
With his parents, Surprenant submitted the winning entry in this year’s Jimmy Fund Big Ideas Contest, which asks the public to make fund-raising suggestions for the Boston charity, which raises money for the Dana-Farber Cancer Institute.
Surprenant’s idea — one of more than 200 entries from 19 states — is “Jimmy Fund Jokers: Laughter is the Best Medicine,” a social media campaign in which people would post Facebook videos of themselves telling jokes, pledge to donate, and tag their friends.
Wearing a jacket and tie on his 4-foot-7-inch frame, Surprenant confidently and charismatically pitched his idea as an inexpensive fund-raiser with potential for global reach — the next Ice Bucket Challenge, he predicted.
He also touted its appeal to young people and the spirit of humor it brings to fighting cancer.
As soon as Surprenant finished, job offers (only half in jest) came pouring in from the six judges.
Red Sox CEO Larry Lucchino offered him a front-office job. Kraft Group president Dan Kraft countered with a position with the New England Patriots. WCVB-TV general manager Bill Fine dangled an on-air gig. Pam Hamlin, global president of Arnold Worldwide, tried to sell Surprenant on the joys of advertising.
Arbella CEO John Donohue seemed resigned that a career in insurance would be a hard sell to a grade-schooler. Friendly’s CEO John Maguire took a different tack, using the allure of unlimited ice cream.
Asked later which offer had most appeal, Surprenant said: “That’s a tough pick, with the ice cream and the Patriots and the advertising, but I think my favorite would be the Red Sox.” Let the salary negotiations begin. — SACHA PFEIFFER
At the Pride parade, more corporate sponsors on board
Saturday’s Boston Pride parade had its biggest corporate showing ever, with 48 sponsors, among them EMC Corp., Liberty Mutual Insurance, Eastern Bank, and Biogen Inc.
Hopkinton-based EMC, in its third year as a sponsor, had 150 staff, friends, and family and a packed Boston Duck Tour boat.
Boston-based Liberty Mutual had a sea of 300 workers and friends who donned spongy crowns in rainbow colors for the 2½-hour route from Copley Square and through the South End to City Hall.
It’s a sign of the times in Massachusetts, where same-sex marriage is a decade old. Today’s Pride parade is more populated by politicians and church groups than drag queens. Think St. Patrick’s Day with a dash of Mardi Gras, drawing spectators of every stripe.
Retail giant Walmart came with a small group but also sponsored a Pride Pageant event. And there were newcomers, like grocer Stop & Shop and Santander.
Banks were a mainstay. Wells Fargo brought its horse-drawn stagecoach, despite a recent kerfuffle with the Billy Graham Evangelistic Association, which closed its account at the San Francisco bank for running ads with gay couples.
TD Bank busted out of cubicle land with a float thumping with dance music and carrying 40 employees from around the region.
“You need to be your whole self at work, and you need to accept those different from you,’’ TD’s Allston branch manager, Mark Lussier said. Besides, “It’s fun to be in the parade.” — BETH HEALY
From Wonderland to Beacon Hill
Dick Dalton had left town for a three-year sojourn in Seattle. But he now has a prominent new role in Boston’s business community after being picked for an economic development job in Governor Charlie Baker’s administration.
You may remember Dalton. He ran Wonderland Greyhound Park as its president and was Wonderland owner Charlie Sarkis’s right-hand man at Back Bay Restaurant Group for years. But Wonderland closed down in 2010 after dog racing in the state became illegal — more than a year before the Legislature approved a casino bill that could have kept gambling alive at the property. Sarkis sold off the bulk of his restaurant business.
With the crumbling of the Sarkis empire, Dalton headed to Seattle in 2011 to help expand a sushi chain for restaurant operator Madison Holdings. Frank Feeney, a lawyer at DLA Piper who represented Sarkis’s businesses, connected Dalton with Madison.
The sushi didn’t catch on as quickly as Dalton wanted outside of Washington, and he ended up back in Boston last year.
When he saw that Jay Ash would be Baker’s economic affairs secretary, Dalton dropped Ash a congratulatory note.
That connection eventually led to a job offer for the position that Dalton started about a month ago: Boston regional director for the Massachusetts Office of Business Development.
Dalton’s job involves helping companies expand here and recruiting new ones into the fold. It also involves a few ribbon-cuttings, such as the opening of Rhonda Kallman’s Boston Harbor Distillery last week on the Dorchester waterfront.
“I’m a Boston boy,” Dalton said. “As much as we enjoyed Seattle, it’s just nice to be home.” — JON CHESTO
Waltham: an economic winner?
The city of Waltham has one of the lowest unemployment rates in the state: 3.3 percent in April. So why is Tom Stanley trying to make economic development a key part of his campaign to unseat the incumbent mayor, Jeannette McCarthy, this fall?
Stanley, a Democratic state representative and a city councilor, argues that it simply takes too long for businesses to navigate the City Hall bureaucracy. He said Waltham’s success is due to the happy accident of its location near Boston and on Route 128, and not to the local government. He then rattled off several specific examples of frustration among those in the business community, like the time officials at the footwear giant Wolverine Worldwide complained to him that they couldn’t reach anyone at City Hall about a potential relocation. (Wolverine ended up deciding to move its offices from Lexington to Waltham, anyway.)
Most notably, Stanley is calling for the creation of a small-business advisory council and for a full-time economic development director, one who could field inquiries from businesses.
But on that latter point, McCarthy said she already has proposed doing something similar, by bestowing those powers on her planning director. The City Council, she said, rebuffed her request. Without the council granting that authority, she said, it’s hard for the planning department to act as a sounding board and a permit champion for businesses.
As far as Stanley’s assertion that Waltham’s economy is falling short, she points to all of the construction that’s under way, including projects within walking distance of City Hall. — JON CHESTOCan’t keep a secret? Tell us. E-mail Bold Types at firstname.lastname@example.org.


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Judge dismisses lawsuit over 2015 Nebraska prison riot
LINCOLN, Neb. (AP) —
A federal judge has dismissed a Nebraska inmate's lawsuit alleging prison officials failed to protect him from gangs and fires in a 2015 riot that left two dead.
The Lincoln Journal Star reports that the lawsuit was tossed out Friday. The judge found no evidence that prison staff were deliberately indifferent to Brian Guerry's health and safety in the May 10, 2015 riot at the Tecumseh State Correctional Institution.
Guerry alleges he was exposed to burning plastic and blood in water in his cell for days after the riot. He alleges prison staff allowed general population inmates to prey on protective custody inmates in the riot.
Senior U.S. District Judge Richard Kopf says prison official's actions were responses to the emergency situation and not due to "sadistic or malicious intent."

domain: law


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Addition of Etanercept and Extracorporeal Photopheresis (ECP) to Standard Graft-Versus-Host Disease (GVHD) Prophylaxis in Stem Cell Transplant
Information source: University of Michigan Cancer Center
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Graft Versus Host Disease
Intervention: stem cell transplant (Procedure); tacrolimus (standard GVHD prophylaxis) (Drug); mycophenolate (standard GVHD prophylaxis) (Drug); etanercept (Drug); methoxsalen (Drug)
Phase: Phase 2
Status: Active, not recruiting
Sponsored by: University of Michigan Cancer Center
Official(s) and/or principal investigator(s):
John E Levine, MD, Principal Investigator, Affiliation: University of Michigan Cancer Center
This research study investigates the benefits and possible risks of adding both etanercept
(Enbrel) and ECP (extracorporeal photopheresis) to the conventional preventative (or
prophylactic) treatments for graft-versus-host disease (GVHD). GVHD is a common, serious,
and too often fatal, complication after matched unrelated donor stem cell transplantation,
regardless of the pre-transplant conditioning regimen used (full or reduced intensity).
Reduced intensity transplants which employ lower doses of chemotherapy during the
conditioning phase of the transplant, are less toxic than full intensity transplants.
Reduced intensity transplants may extend the unrelated donor transplant option to older
patients or to patients with existing medical conditions or illness, where a full intensity
transplant is not possible. To be successful, reduced intensity transplants need to offset
any lower effectiveness in killing cancer cells during the conditioning phase, with the
establishment of a donor cell, graft-versus-leukemia effect (GVL). The GVL effect and GVHD
are associated with each other and therefore, the goal of GVHD prophylaxis for this study is
not so much to prevent all GVHD, but rather to prevent serious and fatal acute GVHD.
Most GVHD-related deaths are either the direct consequence of severe GVHD or from infections
associated with intense immunosuppression, a consequence of the standard treatments for
acute GVHD, which almost always include high-dose steroids. A more effective prophylaxis
therapy that allows for the GVL effect to develop, while limiting the exposure to high-dose
steroids may reduce transplant mortality and morbidity. We also will study how key chemical
and cellular factors relate to clinical outcome.
Official title: Addition of Etanercept and Extracorporeal Photopheresis to Standard GVHD Prophylaxis in Patients Undergoing Reduced Intensity Unrelated Donor Hematopoietic Stem Cell Transplant
Study design: Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Prevention
Percentage of Patients Alive at 6 Months
Percentage of Patients Who Experienced Relapse by 6 Months
The Percentage of Patients That Experienced Graft Versus Host Disease
Effect of This Prophylaxis Regimen on Plasma Markers of Inflammation After Transplant
To Correlate Regulatory T Cell Numbers Post-transplant With GVHD Outcomes
To Correlate Donor and Host Inflammatory Cytokine Gene Polymorphisms on Clinical Outcomes Observed During the Trial
Minimum age: N/A.
Maximum age: N/A.
- Candidate for unrelated donor (allogeneic) HSCT for hematologic conditions, either
malignant or non-malignant.
- Donor can be unrelated marrow, blood or cord blood.
- Any disease for which unrelated donor transplant is appropriate is eligible except:
- Progressive or poorly controlled malignancies for which the likelihood of
durable disease control [i. e., patients expected to have at least 6 months PFS
from date of transplant] is <25%.
- This determination of likelihood of durable disease control must take into
account the patient's disease status and consideration of the agents and doses
used in the reduced intensity conditioning regimen.
- The determination of adequate disease control will be certified by the PI or
designee on the eligibility checklist.
- Patients may be consented to this trial based on disease control at the time of
consent, but later removed from the trial prior to initiation of transplant
conditioning regimen if disease status confirmation between consenting and
transplant changes. In the event this occurs these patients will be replaced.
- Must be receiving a recognized reduced intensity transplant as determined by the
University of Michigan Blood and Marrow Transplantation Program.
- Patients age 50 or older are eligible based on age.
- Patients may be <50 years old if they are eligible for a reduced intensity
conditioning regimen based on disease type (eg, indolent lymphoma) or if
comorbidities preclude a full-intensity transplant.
- Patients must have adequate venous access by either peripheral vein or central line
so that ECP can be performed.
- Patients must be expected to tolerate the fluid shifts associated with ECP. The
primary reason for expected intolerance of ECP is small size (ie, <30kg weight), but
other factors may also be considered in this determination.
- Not a candidate for a reduced intensity transplant conditioning regimen (based on the
current U-M BMT program clinical guidelines).
- Patient has a suitable related donor available for transplant.
- Karnofsky or Lansky performance status of < 50% at the time of admission for HSCT
- Patients with evidence of HIV infection or other opportunistic infection including
but not limited to Tuberculosis and Histoplasmosis.
- Patients with active bacterial, fungal or viral infection not responding to
- Any medical or psychological conditions that would keep the patient from complying
with the protocol and/or would markedly increase the morbidity and mortality from the
- T-cell depleted allograft
Locations and Contacts
University of Michigan Cancer Center, Ann Arbor, Michigan 48109, United States
Starting date: March 2009
Last updated: September 19, 2014

domain: medical


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Armed Gardaí are set to patrol the streets of the city next week -
It's in a bid to crackdown on the Hutch/Kinahan feud.
The Herald says today that the Armed Support Unit will operate 24 hours a day, starting Monday.
55 members will be on duty, with 15 on-call.
The Unit was announced after February's attack at the Regency Hotel.
Colleagues of Trevor O'Neill have set up a fundraiser for his family. The Drimnagh man was gunned down last month in Majorca, in a case of mistaken identity. It's believed a member of the Hutch family was the target. Dozens of Trevor's Dublin City Council colleagues have now started a fund to help his partner and three children.

domain: news


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Dennis Truscello / Naples Daily News
The 1970s hitmaker and beloved actress has been forced to cancel all of her upcoming shows through the end of May 2017 due to the effects of a spinal condition she has suffered for some time now.
In an announcement to fans on her social media accounts, Olivia Newton-John‘s management team explained that the country, pop, and musical star would be canceling all the performances scheduled throughout the Midwest in May. They also noted that new dates would be announced as soon as possible to make up for the cancellations.
Citing a “bad issue” with sciatica, management did not say if there would be any changes to her other dates scheduled for June and other months in the year. All of her Midwest shows were scheduled between May 10th – 20th.
Newton-John rose to popularity in the country music community after the launch of her 1973 single, “Let Me Be There” which soared across multiple charts and earned the No. 2 spot on Billboard’s US Country Chart. She also earned a Grammy Award for Best Country Female Performance for her work on the song.
Our thoughts and prayers are with Olivia Newton-John during this time and we wish her a very speedy recovery.
Watch one of her stunning performances of “Let Me Be There” from 1973 in the video below!
Interested in becoming a partner?
Contact us for more info.

domain: celebrity


Said to be economical for spans between 24 and 34 feet, a patented composite floor system consists of hollow-core precast planks supported at the ends by composite beams. The planks are set on precast beam forms that are supported by scaffolding. Beams are then cast by filling the pocket between the ends of the planks with concrete.
Placing concrete for an addition to a water treatment plant in North Dakota was complicated by limited access to the construction site.
Strap on the backpack harness, turn on the air compressor, grip the handles, and slowly walk backward--this is all that is required to operate this aluminum vibratory screed. One worker who actually wears the screed can position and maneuver it.
The $4.6 million contract to rehabilitate a bridge on Interstate 190 near Grand Island, New York allowed 18 months for construction. Based on a visual inspection of the bridge, the contract called for the removal of 14,000 square feet of bridge deck. Deteriorated surface concrete was to be removed to a depth of at least 1 inch below the top reinforcing steel.
To select blades or bits for cutting concrete, a contractor doesn't need to know how they are made, but he should know how they will be used--the type of concrete he has to cut and the machine he plans to cut with. A manufacturer of concrete cutting equipment can then recommend a blade or bit that will match the concrete and the machine.


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How We Are Fighting COVID-19 in Brazil
The coronavirus is raging in Brazil. It has been hit harder by the pandemic than any other country in the world other than the United States. The biggest problems are occurring in the slums of the megacities São Paulo and Rio de Janeiro. Yet the coronavirus now has also reached the indigenous peoples further inland.
A few weeks ago, one hundred black crosses rose out of the sand on the Copacabana, where Brazilians and tourists otherwise frolic. A sign reads: “Brasil, país das covas” (“Brazil, land of the graves”). The crosses on Rio’s famous beach are meant as silent monuments to the victims of the pandemic. At the same time, excavators are digging real mass graves in many parts of the country. Brazil has become the epicenter of the corona pandemic. For weeks now, the country has been reporting 1,000 deaths each day as a result of COVID-19, more than 2 million people are infected.
The Situation in Brazil Is Complicated
“We are going through a bad crisis,” says Marc Reichardt, Senior Bayer Representative for Brazil. The crisis has now lasted for nearly four months. Bayer reacted quickly when the coronavirus appeared in Brazil: many employees had already been working from home even before the government mandated quarantine measures. Strict safety measures such as social distancing, mandatory facemasks and fever measurements were introduced at Bayer’s Brazilian sites to protect people at the local level.
Bayer is supporting the fight against the corona pandemic worldwide with the help of its products, technical equipment, know-how and the dedication of its employees
You can find a current overview at:
Many people feel anxious. “We’ve therefore sent daily updates on the situation to our employees,” reports Marc Reichardt. There are also tips on mental and physical health, virtual discussion circles and open doctor’s consulting hours that are available around the clock.
“Mission COVID-19”: How Bayer Employees Are Fighting the Pandemic Together
In March, the Bayer LifeHub São Paulo launched the ''Mission COVID-19''. The campaign aimed to mobilize employees to come up with ideas on how to overcome the crisis. The response was huge: Employees contributed numerous ideas in the areas of education, mobility, optimization of health services, tips for emotional and physical health, services for elderly people at home, and proposals for retail, commerce, and logistics. Thanks to their suggestions, Bayer joined forces with external partners and distributed 8,000 litres of hand sanitizers.
“Innovation and collaboration are essential if we want to positively impact society and contribute to our sustainable development goals,” explains Caspar van Rijnbach , Head of IT and Digital Transformation Brazil. “By working collaboratively, we can give back especially to the communities in which we live and work.”
Employees at the Uberlândia site repurposed 3D printers in order to produce masks for the local hospital. Others sewed by hand and donated hundreds of community masks together with friends. Together with two other Brazilian companies, Bayer employees organized 80,000 hand disinfectant bottles for the Hospital de Amor Barretos in São Paulo – an amount that will cover the hospital’s needs for about 30 months. In addition, 2,000 Bepanthen products were donated to health workers to help them protect their skin under the facemasks.
The situation in São Paulo has eased somewhat, but it’s too early to sound the all-clear. The virus is now spreading in the hinterlands, where hospitals and laboratories are sometimes several days’ journey away. This means COVID-19 also presents a deadly threat to Brazil’s indigenous peoples, such as the Yanomami. The reservation lies in the far north of Brazil, deep in the rain forest that borders Venezuela. Yet not even this seclusion is protecting the Yanomami from the pandemic, as loggers and gold prospectors are bringing the virus to their region. The Yanomami currently are not permitted to leave their villages, and are observing social distancing and quarantine rules on their land.
Further Immediate Relief: Bayer Donates One Million Euros
Infrastructure and care in these remote regions are poor. In order to reach people there, Bayer is collaborating with government agencies, health authorities and other organizations such as UNICEF and donated one million euros (5.7 million Brazilian real) to support aid initiatives. The donation to UNICEF benefits particularly children, young people and socially disadvantaged segments of the population in these regions, as well as relief campaigns initiated by the Brazilian government and the national health system.
“The crisis caused by the COVID-19 pandemic challenges all of us. The collaboration between the public and private sectors and civil society will be crucial to overcome these challenges,” says Marc Reichardt. “Our contribution goes far beyond financial support: our employees are working around the clock to maintain the availability of medicines and food in Brazil – fully in keeping with our vision ‘Health for all, hunger for none.’”
This Is How Bayer Is Helping:
Financial aid: Bayer donated EUR 1 million to support the fight against COVID-19 in Brazil.
Poduct Donations: In partnership with Usina Alcoeste and Coca-Cola Brasil, Bayer donated 80,000 bottles of gel alcohol to the Hospital de Amor de Barretos, in upstate São Paulo. 2,000 units of Bepantol Derma were delivered to healthcare professionals at the forefront of the fight against the epidemic.
Social engagement: Employees in Petrolina mobilized to collect financial contributions to help families in need. The amounts were reverted into purchasing 224 units of staple food baskets, totaling more than 2,600 thousand kilos of food. Other employees participated in a blood donation campaign for the Hemolina Regional Petrolina (HEMOPE), which reported low stocks. In Santa Cruz das Palmeiras a group donated extra pieces of cloth and rubber bands from the local facilities to the Social Assistance of Santa Cruz das Palmeiras, in upstate São Paulo. The supplied materials were used for producing more than 300 cloth masks.
Partner and networks: Bayer collaborates with universities and other companies and supports projects of the Brazilian government, the national health system and UNICEF.


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The giant Online Shopping platform in Nepal, Daraz is all prepared to bless Nepalese consumers with its Daraz 11.11 2020 Sale. The single-day sale festival is the world’s biggest sale day and kicks of this November 11, 2020 (Kartik 26, 2077). Daraz organized a virtual campaign to inform people/media of the 11.11 event, along with the answer to the queries.
Daraz 11.11 2020 Sale is highly motivated to present all Nepalese consumers with the high discount rates and price drops in every product. Plus, you can get an extra 20% Off (Up to Rs. 3000) via using debit/credit cards on the Daraz app. The card should be one of 11 banking partners of Daraz. NabilBank, Sanima Bank, NIC Asia, Global IME Bank, NMB Bank, Mega Bank, Nepal Bangladesh Bank, Kumari Bank, Laxmi Bank, Century Bank, and Himalayan Bank. Even eSewa users can expect special discounts but that is for limited hours.
Daraz Virtual Campaign
The hype for the World’s biggest sale day is building day by day. Daraz even hosted a Live Virtual Campaign with Suraj Singh Thakuri to answer all the questions and queries from media as well as consumers. In this Live event, all the answers were given directly from Daraz’s important personals such as Lino Ahlering; MD, Santosh Bista; Head of Daraz Express, and; Samjhana Subedi; Chief Customer Officer.
Santosh Bista; Head of Daraz Express stated “We’ve hired more than 700 delivery staff just for 11.11. Working with six other logistics partners our capacities along with our infrastructure and technology have significantly improved. As the pandemic is still at large, we’re especially screening and training our riders to ensure a safe and optimal customer experience, too.“
Samjhana Subedi; Chief Customer Officer followed up later by saying “In order to ensure we’re able to fulfill customer demands, we’ve hired close to 200 customer and seller care agents for 11.11. We’ve further extended our operating hours so customers can reach out to us via live chat on social media.”
Host, Mr. Suraj Singh Thakuri was even convinced that Daraz is all prepared to meet the expectation for the World’s Biggest Single Day Sale Festival in Nepal.
On Daraz 11.11 of 2018, Poco F1 was launched which went out of stock quickly and even disturbed the Daraz System for some time due to enormous request. Well, this time around Samsung is launching its Samsung Galaxy S20 FE in Daraz 11.11 2020 Sale at just Rs. 69,999. Daraz claims this is the world’s best deal.
Similarly, products from national and international brands like LG, Xiaomi, Fitbit, Sony, Vans, Whirlpool, Titan, Columbia, Mheecha, Goldstar, Juas, Home Glory, Amays Fashion House, New Balance, Realme, TVS, and more have up to 60% discount. This follows the same for home appliances, men’s women’s clothing, fashion accessories, musical instrument, cosmetics, and as well as others. Coca-Cola, Premium Sponsor of Daraz 11.11 2020 will also announce special offers in the World’s Biggest Single Sale Day Festival (11.11).
Daraz is also hosting games, contests, and competitions for Nepalese consumers in which they can exciting prizes and vouchers. Ludo Tournament, 1 Ruppe Game, Mission 11, Add to Cart and Win are such kinds of stuff. Adding more to this, consumers can win a brand new TVS Apache RR 310 bike worth Rs. 8 Lakh. All you will have to do is shop during Daraz 11.11 2020 Sale day.
Newly launched Products from Mobvoi and Fitbit will also have discounts on the occasion of Daraz 11.11. Black Shark 3 which is still available in Daraz might be one to grab. Poco might include their two new phones launched in Nepal; Poco C3 and Poco M2 on this sale day. It’s not sure but there’s a possibility for the availability of Poco Phones there. However, we can expect that the World’s Biggest Single Day Festival for this year is going to be better than what it used to be.


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The famous and remarkably so Round Tower situated in the heart of Copenhagen is one of Europe’s most beautiful yet oldest observatory, which functions to date. This architectural marvel offers not only a breath taking view of the constellations but also of our beloved Mother Earth. The Round Tower was built in the 17th century. Denmark’s astronomical accomplishments in the period were so much so that we would not know the universe as we do today, without them.
The Round Tower makes a beautiful tourist spot and is easily accessible with public transport. Its location in between channels ensures that you can make the most of its well-kept beauty. This tower has been serving the public ever since 1642. Also today, the tower offers one of the best possible views in all of Copenhagen. If you want to enjoy a panoramic view of the city’s skyline, there is no better spot than this historical tower.
Today, standing tall taking pride in its rich history, the Round Tower was to begin with a fusion of a church, an observatory and a library. Home to great knowledge and learning, it was a part of the Trinitatis Complex. The tower has been kept in its original form and does not for the very reason have an elevator. The white washed spiral walkway that leads to the top has been used for centuries. The spiral walk comes with its uniqueness of the European architecture of its time.
The stairway is a majestic 209 meter long spiral frenzy and is a marvelous work of great craftsmanship. The spiral winds itself a whopping 7.5 times around as it paces up the hollow core of this antique tower. This spiral ramp is the only connection in between the individual parts of this majestic construction.
Though initially made for the University of Copenhagen, today, with all its equipment, this grand observatory is open to public and anyone can marvel the wonders of the sky. Many of the world’s best astronomers have used this observatory. These include the famous Ole Rømer (1644-1710) and Peder Horrebow (1679-1764). The tower was built specifically for students and scholars, but today is laden with relics of history and makes a great window in to the 17th century Denmark.
Many stories and anecdotes have been written about the Round Tower over the years. One legendary one was written by the world famous author Hans Christian Andersen (1805-1875). He wrote the fairy tale The Tinder Box in 1835, where a soldier meets a dog with eyes as big as the Round Tower.
The Round Tower is a must-see when in Copenhagen. From the facade to the interior, from the library to the observatory itself the tower does not fail to inspire awe for all those who come to visit it making it not only a landmark but also one more reason to look forward to your trip.

domain: geography


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It's set to screen at this year's London Film Festival and now we can reveal a gorgeous exclusive poster for Rust and Bone.
The moving drama, starring Marion Cotillard and Matthias Schoenaerts, tells of a relationship between a seriously injured whale trainer and a unemployed bare-knuckle boxer.
SCROLL DOWN TO SEE THE POSTER IN FULL
Here's the official synopsis for the Jacques (A Prophet) Audiard film, due for release in the UK on November 2nd;
Jacques Audiard, acclaimed director of A Prophet and The Beat That My Heart Skipped, returns with this powerful, tender romantic drama about two people from very different worlds seeking redemption in each other.
Marion Cotillard (La Vie En Rose, Inception) stars as Stephanie, a killer whale trainer who late one night meets Alain (Matthias Schoenaerts, Bullhead) in a fracas at the nightclub where he works as a bouncer.
Put in charge of his young son, Alain has come from Belgium to Antibes to live with his sister and her husband as a family.
Alain's bond with Stephanie grows deeper after she suffers a horrible accident, bringing the two together once more.

domain: artistic


I look forward to working with the Foreign Minister of Nepal: S. Jaishankar
KATHMANDU: SEPT. 23 – Indian External Affairs Minister S. Jaishankar has congratulated Dr Narayan Khadka on his appointment as Nepal’s Foreign Minister. On social media, the Indian External Affairs Minister congratulated Khadka and said that he was looking forward to working with him.
Meanwhile, Foreign Minister Khadka and his Indian counterpart are expected to hold talks in New York. While attending the 76th General Assembly of the United Nations, the Foreign Minister of India is currently in New York and the Foreign Minister of Nepal is also arriving in New York.
The informal meeting of the foreign ministers of the SAARC countries, which is being organized by the current chair of the South Asian Association for Regional Cooperation (SAARC) Nepal in the context of the General Assembly, has been postponed this time. The meeting has been postponed due to recent developments in Afghanistan.


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Everton will announce the signing of James Tarkowski on a free transfer at the end of next week and are busy working on more deals throughout the summer.
Toffees boss Frank Lampard is determined to improve his squad after their relegation near miss. Everton must also deal with the uncertainty over the futures of strikers Dominic Calvert-Lewin and Richarlison with both players wanted by some of their Premier League rivals.
Mirror Sport has the latest Everton transfer news and rumours, including updates on Andre Gomes and their interest in a Watford striker potentially looking for a move to Goodison Park.
Gomes could leave
Football Insider claims Andre Gomes will leave Everton if they sign Harry Winks from Tottenham. Everton are keen on Winks and the report says his arrival would lead to Gomes' departure because the Blues need departures to help balance the books. The report cites Everton sources claiming Gomes would want to leave because his first-team opportunities could be hit by Winks' arrival. That deal is still some way off and Tottenham want £20million for Winks, while the Blues would prefer a loan deal for next season.
HAVE YOUR SAY! Who should Everton sign and sell this summer? Let us know in the comments section
Lampard eyes Hornets striker
Everton boss Lampard is looking at strikers with the futures of Richarlison and Calvert-Lewin shrouded in uncertainty and is being linked with Watford's Emmanuel Dennis, according to FootballFanCast. Dennis performed well during Watford's disappointing relegation campaign and managed 10 Premier League goals and six assists. This form has alerted Everton and the Nigerian international could leave Vicarage Road following the Hornets' relegation. Everton could land Dennis for around £20million according to the report.
CalcioMercato claim Everton have joined Newcastle, AC Milan and Marseille in the bidding for Roma's Jordan Veretout. The Frenchman helped Jose Mourinho's Roma win the first-ever Europa Conference League and he is reportedly valued at £13million. Veretout had an ill-fated spell at Aston Villa a few years ago and he was part of the side relegated from the Premier League in 2016. Mourinho may be prepared to cash in on Veretout, who has two years left on his Roma deal, having just signed Nemanja Matic on a free from Manchester United.


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Please do not enter the school parking area from Wilson Avenue on school days 7–7:30 a.m. This entrance is reserved for the buses. If you are dropping off your child, please use the side pedestrian entrance on Wilson Avenue where the school crossing guard is present. Thank you for helping us keep our students and staff safe.
Dr. Lyman T. Johnson
We honor Dr. Lyman T. Johnson who is the namesake of our great school, born on June 12, 1906. Dr. Johnson was a civil right leader and an outstanding educator. Dr. Johnson taught at Louisville Central High School for thirty-three years and served nearly ten years as assistant principal and school board member in the Jefferson County Public School system. He successfully challenged the University of Kentucky and was the first African American to attend there. Now, the University of Kentucky has a residence hall, an alumni association, and a scholarship in Dr. Johnson’s name. In addition, Dr. Johnson was awarded the Governor’s Distinguished Service Medallion for Volunteerism and the City of Louisville’s first Freedom Award. Our Johnson students exemplify Dr. Johnson’s legacy every day!

domain: history


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Aduana Stars midfielder, Prince Acquah was named Man-Of-The-Match in his team’s victory over Accra Hearts of Oak at the Nana Agyemang Badu Park on Wednesday afternoon.
The former Kumasi Asante Kotoko SC man was very instrumental for the Fire Boys in midfield and his stellar performance was rewarded with a man of of the match award.
Striker, Yahaya Mohammed scored the opening goal of the match on the 44th minute to put the Green and Yellows in a 1-0 lead before the first half whistle was blown by the center referee.
Sixty seconds after the break, Acquah scored a pile driver from almost 40-yards out to put the hosts 2-0 up early in the second half of highly contested game.
There was late drama as Hearts of Oak left-back, Raddy Ovouka missed a spot kick and subsequently missed a glaring chance when he failed to put a loose ball into an empty net.
The game finished 2-0 to the hosts who won their first game of the season to inflict a second leg defeat to their opponents to move out of the relegation zone.
The former Kotoko man received his first Man-Of-The-Match award in the 2020-21 Ghana Premier League season.
By Delrand Nii Ansah Mensah


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Twitter is testing a new feature that -- if implemented -- will prominently flag misleading tweets from politicians and other public figures, according to NBC News. As seen below, the feature adds red and orange badges to tweets the company has deemed "harmfully misleading," followed by information from verified fact-checkers and journalists.
For example, in the tweet below about the similarities between coronavirus and HIV, the follow-up message clarifies that a lot of viruses share traits with HIV. It also adds that there's no evidence to suggest coronavirus is human-made. Critically, the feature gives accurate information as much prominence as the original tweet.
Twitter emphasized to NBC News the feature is "one possible iteration" of a new anti-misinformation policy the company plans to implement on March 5th, the same day its recently announced ban on deepfakes goes into effect. "We're exploring a number of ways to address misinformation and provide more context for tweets on Twitter," a spokesperson for the company told the publication. "Misinformation is a critical issue and we will be testing many different ways to address it."
In turn, the flagging system could be complemented by another upcoming feature that would allow people to earn points and badges for helping the company moderate the platform. According to NBC News, the demo it saw asked users to rate how "likely" or "unlikely" they thought a tweet was "harmfully misleading." Using a sliding scale between 1 and 100, they then had to rate how many other people would answer in the same way. As with the flagging system, Twitter emphasized it may not implement the community feature. "This is a design mock-up for one option that would involve community feedback," the company told NBC News.
Twitter has reportedly been working on tools to stop the spread of misinformation since at least 2017. With the 2020 presidential election coming up, the company recently announced a feature that will allow people to report tweets that share misleading information about how and where to vote. Beyond the tools detailed in this latest report, it's likely the company has other ones in the works as well.


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Also called digital or virtual currency, is a type of decentralized currency which is not backed by any central or government authority. Due to this, the tax treatment of cryptocurrency is complex and may differ depending on the country in which you reside.
Within the United States, the IRS has issued guidance stating that cryptocurrency is treated as property to the tax purpose. This means that transactions involving crypto are subject to capital gains and losses, just like transactions involving other types of property.
If, for instance, you buy cryptocurrency, and sell it at a higher price then you’ll be able to claim an increase in capital that has to be declared on your tax return. Conversely, if you sell the cryptocurrency at less than what you paid for it, you’ll have an income tax deduction that could be used to offset other capital gains or as much as $3,000 of ordinary income.
In addition to capital gains and losses, you may also be taxed on any cryptocurrency you receive as payment for services or goods. The income you earn is reported as income on tax returns and will be taxed at the exact rates as other types of income.
It’s also important to remember that platforms and exchanges where you purchase, sell, or trade in cryptocurrency must submit certain transactions to the IRS Therefore, the IRS might have information on your cryptocurrency transactions even if you don’t report them on your tax returns.
It is important to note that the information in this report is intended for informational purposes only . It should not be considered tax, legal or financial advice. Each person’s financial situation is individual, and you should consult a qualified tax professional prior to making any decision regarding your tax situation.
In addition there are laws and regulations regarding cryptocurrency taxes may change over time and could vary depending on your location. It is your obligation to ensure that you are in compliance with all applicable laws and regulations.
In short the cryptocurrency is considered property for tax purposes for tax purposes in the United States, and transactions involving cryptocurrency may result in capital gains or losses and also income tax. It is important to consult with a tax professional and stay up to date with the laws and regulations to ensure compliance.
The information contained in this report is for informational only and does not constitute advice on tax, legal or financial advice. The information contained in this report is not applicable to all individuals or scenarios. Laws and rules surrounding cryptocurrency taxation may change over time and could vary depending on your location. It is your responsibility to make sure you comply with all pertinent laws and laws. This report is not a substitute for professional legal or financial advice. You should seek advice from an experienced attorney or financial advisor before making any decision regarding your tax situation.
The information in this report is for informational purposes only and is not meant to be considered as financial advice. Each person’s financial situation is unique, and you should consult with a qualified professional before making any decisions regarding taxes. The information on this page is based on data that were available at the time of the report’s creation and could be subject to change in the near future. There is no guarantee as to the accuracy or completeness of the information is given. The risk of investing in cryptocurrency is high and you should speak with an expert in financial planning before making a decision to invest. The past performance of cryptocurrency does not guarantee future results. The report is not intended to serve as a general reference for investing or as a source of any specific investment recommendations or recommendations. It does not make any implied or express recommendations concerning the way in which an individual’s account should or would be managed, since the proper investment decisions are based on the particular investment goals of the person.


Greg Warmoth and "Central Florida Spotlight" preview the Lake Nona Impact Forum set for Feb. 24-26 in Lake Nona. The program airs at 12:30 p.m. Sunday on WFTV-Channel 9. The guests are Pat Geraghty, chairman and CEO of GuideWell and Florida Blue; Gloria Caulfield, executive director of the Lake Nona Institute; and Thomas J. Graham, M.D., global chairman of Lake Nona Institute and chief health strategy and innovation officer at Tavistock Group. The forum is in its fourth year and will bring to town Deepak Chopra, Billie Jean King and other celebrities. "Central Florida Spotlight" examines what the forum means to the community.


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This Puppy Found A Home!
Midge is a sharp looking Rottweiler puppy with a friendly nature. This hefty pup can be registered with the AKC and comes with a health guarantee provided by the breeder. She is vet checked and up to date on shots and wormer. To find out how you can welcome Midge into your loving home, please contact the breeder today!

domain: pet


Lawmakers have unveiled the agenda for women's health in Pennsylvania.
Members of the Women's Health Caucus gave details on seven pieces of legislation that focus on a wide range of women's health from safety to workplace accommodations.
House Bill 1892, sponsored by Rep. Mark Painter (D-Montgomery), would require a covered employer to make reasonable accommodations related to pregnancy, childbirth or related medical conditions.
House Bill 1895, sponsored by Rep. Mary Jo Daley (D-Montgomery), would require employers to provide a private, clean place for employees who need to express breast milk, for up to one year after birth of their child.
House Bill 1891, sponsored by Rep. Matt Bradford (D-Montgomery), would create a 15-foot buffer zone around health care facilities where picketing, patrolling or demonstrating that blocks patient access to facilities would be banned.
Senate Bill 1212, sponsored by Sens. Rob Teplitz (D-Dauphin/York) and Anthony Williams (D-Philadelphia), would clarify and update the legal standards for pay equity lawsuits.
House Bill 1900, sponsored by Rep. Maria Donatucci (D-Philadelphia/Delaware), would allow women between the ages of 30 and 65 to qualify for the state Healthy Woman Program allowing for earlier screenings.
House Bill 1796, sponsored by Rep. Todd Stephens (R-Montgomery), would ban municipal ordinances that penalize victims for calling for help.


enrose, announced that legislation would be tabled on Thursday, requiring a licence fee to be paid by those active in placing bets on racing, and other sports, as well as gaming activities, with firms outside the UK.
Penrose said the revamped industry would be based on the point of consumption rather than point of supply, however no detail was given on the tax system this would involve, which jurisdictions would be affected or when this would come into force.
“It means anybody based anywhere in the world who wants to sell gambling services to any consumer based in the UK will, in future, have to have a Gambling Commission licence,” Penrose said.
Specific details of the amounts involved, and the distribution of what is perceived as a new betting tax, have yet to be clarified. Racing’s slice of such a tax, which has become a major issue in times of an ever-decreasing Levy, is unknown.
Since major bookmaking firms such as Ladbrokes, William Hill, Betfred, as well as Betfair, the betting exchange, moved offshore, many millions in revenue have been lost to the Treasury, as well as contributions to racing through the Levy.
In other news, Eddie Ahern will miss the whole of Glorious Goodwood after being hit with an additional 14-day ban for an incident that happened in Sweden on May 31.
Ahern was originally given a seven-day suspension by the local stewards for an offence in the Group Three Stockholms Stora Pris at Taby.
Any new licensing system would require a change in primary legislation with analyst James Hollins of Evolution Securities suggesting that this could “push full implementation out to 2013 or 2014”.
“We think that the taxation discussion will come prior to implementation as and when the Treasury gets involved,” Hollins said, however he warned that the suggestion that offshore operators are not “bearing a fair share of the costs of regulation firmly implies, in our opinion, that taxation will become part of the new legislation.”
Currently any gambling operator offering services in Britain must be licensed or regulated in either an EEA state or one of the states approved by DCMS on the White List that includes Gibraltar, the Isle of Man, Alderney, Malta, Antigua, Tasmania and Curacao.
The new proposals would effectively mean the end of the White List as it stands, however Penrose added that the Gambling Commission would ensure that regulatory good practice is recognised so that overseas based businesses in “trusted jurisdictions”, such as the white listed countries, would have much “lighter touch approach and, for example, will not have to duplicate regulatory work.”
In between a final decision being made on licensing and taxation all white-list located entities will be entitled to a transitional licence and can continue trading as normal.
Allan Bell, Isle of Man Minister for the Department of Economic Development, called the decision to treat trusted jurisdictions such as the Isle of Man with a lighter touch "encouraging".
"Under the automatic transitional license Isle of Man based companies will have a streamlined point of entry and significantly reduced administrative costs when they obtain a UK license. In my recent conversation with Minister Penrose I received assurances that the UK Gambling Commission has no wish to duplicate the work that our Gambling Commission does in regulating our operators.”
“The eventual timescale for these proposals to enter into force are not yet determined and before the proposals become law we will remain in close dialogue with the UK Government to ensure that the interests of our sector continue to be heard. Alongside this the Isle of Man Gambling Supervision Commission will work with its counterpart in the UK to establish how they will work effectively together under the new regime," Bell added.
"The current system for regulating remote gambling doesn’t work, John Penrose added. “Overseas operators get an unfair advantage over UK based companies, and British consumers who gamble online may have little or no protection depending on where the operator they deal with happens to be based.
“We will create a level playing field, so all overseas operators will be subject to the same standards and requirements as those based in Britain, as well as being required to inform the Gambling Commission about suspicious betting patterns to help fight illegal activity and corruption in betting,” Penrose concluded.
Clive Hawkswood, CEO of lobby group the Remote Gambling Association, said the main players in the UK online gambling market “already adhere to high regulatory standards” comparable to those in Britain adding that regulation by the Gambling Commission “holds no fears” for the group’s members.
However, he warned that a significantly higher tax burden, “that could lead to a reduction in value and choice for consumers”, certainly does [hold fear]. “It is therefore crucial that any new regulatory regime is complemented by a fair and sustainable fiscal regime.”


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Knowingly false information about a special operation in Ukraine was found on the journalist's Telegram channel. In 2015, Reznik was sentenced to three years for insulting officials and falsely reporting a crime. After his release, he left for Georgia
A case was opened against a journalist from Rostov-on-Don, Sergei Reznik, under an article on the dissemination of false data about the use of the Russian Armed Forces, RBC was told in the press service of the regional UFSB.
“The FSB of Russia in the Rostov region documented the involvement of the Rostov journalist Sergei Reznik in the publication in his Telegram channel “Sergey Reznik” materials containing deliberately false information about the goals, objectives and procedure for conducting a special military operation by Russia on the territory of Ukraine”, — stated in the press service.
St. 207.3 of the Criminal Code on the public dissemination of false information about the use of the Russian army provides for a maximum penalty of 15 years in prison.
Reznik left Russia a few years ago and lives in Georgia. He specializes in anti-corruption issues, at various times he worked in the Novaya Gazeta & mdash; South", «Izvestia— South", «MK— South", "Southern Federal" and others.
In November 2013, the court found Reznik guilty of knowingly false denunciation, commercial bribery and insulting a government official and sentenced him to 1.5 years in prison. In January 2015, a court in Rostov sentenced Reznik “on a cumulative basis” to three years in a penal colony, taking into account the already served sentence. He was also banned from working in the media for two years after his release. He was accused of four episodes of articles “false report of a crime committed”; and “insulting officials.” In October 2016, Reznik was released.
In October 2021, the Ministry of Internal Affairs put a journalist on the wanted list in the case of the rehabilitation of Nazism (part 4 of article 354.1 of the Criminal Code) because of “desecration of the symbols of Russia's military glory, insulting the memory of the defenders of the Fatherland and justifying the regime of fascist Germany,” the FSB specified. Reznik himself said that the cases against him were “ordered”.
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Senator Bernie Sanders, the self-described democratic socialist, received $5.9 million from about 223,000 donors in the 24 hours after he announced his repeat bid for the U.S. presidency.
In total, the Vermont independent has raised $6 million, with small-dollar pledges mirroring the average donation of $27 from his 2016 run, according to his campaign. The fundraising rose from the $4 million the campaign said he amassed as of the evening of Feb. 19, the day he announced.
Sanders, 77, is seeking to become the Democratic Party’s nominee. His fundraising effort eclipsed that of Senator Kamala Harris, whose initial $1.5 million from about 38,000 donors had been the biggest first-day money haul of the 2020 race so far. The California Democrat announced her bid for the Democratic nomination Jan. 21.


Ballet Dance Slippers – Black
Sole: Suede – Canvas
Shoe Width: Medium
Soft and breathable, these canvas Ballet Dance Shoes.
Perfect for young dancers for dance class, gymnastic exercise, yoga, stage performance etc.
A must-have for every ballet dancer.
These soft sole canvas ballet shoes are high in comfort, durability and fit.
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The 2 crossover straps allow you to move freely and keep you in form while practicing.
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Outsole material – Soft sole Insole material – PU (*PU – very durable double density polyurethane sole).
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Ballet Dance Shoes (Black) for all age groups, from dance to yoga.
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Wear and slip resistance, mute, can well show the perfect foot curve. Recommended by professional ballet instructors.
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24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36


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Fortress Investment Group Determined to Maintain Industry leadership
Notable efforts have been realized by Fortress Investment Group in the quest for the maintenance of the industry performance leadership. Since its formation, Fortress Group has been on the move towards achieving its fundamental goals which are the provision of quality services to its clients and also maximizing yields for its investors. These objectives have kept the company on toes and motivated it to put more efforts which have indirectly led to the company becoming the champion of the investment industry. Fortress Investment Group has also demonstrated tremendous growth that has made it recognized by a lot of investors who are always willing to put their wealth under the management of the company.
Fortress Group is propelled by various fundamental principles that have been designed and maintained through the organization’s stable leadership. One of the principles is the efficient and proper management of the company’s operations. The organization has developed management tools that are very robust in the monitoring of its investment strategies which at times are quite sophisticated. This helps the company to ensure that its operations can deliver value to its clients by providing impressive yields from their investments. This has been successful through close monitoring and evaluation of its strategic and operational facts on the ground to ensure that any trends in the investment market are properly analyzed, and their impact acknowledged.
Another aspect that has led to the flourishing of Fortress Investment Group is that of its asset-based strategy of investment. During the formation stage in 1998, Fortress Group’s main focus was on the management of private equity as the main source of investment funds. Later on, the management of the company contemplated the reduction of the company’s investment risk by diversifying its investment portfolio. This led to the introduction of other asset classes like the real estate, credit funds, hedge funds and other forms of traditional investment vehicles.
This led to the drastic growth of the assets under the management of Fortress Investment Group to the extent that it even won some of the industry awards that recognize the best performing organizations in the industry. Currently, Fortress manages assets worth more than $64 billion on behalf of its valued clients.

domain: finance


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SUMMARY: Our outpatient Physical Therapy and Sports Medicine team is looking for a Physical Therapist to join us at our satellite clinic at 9501 North Oak Trafficway, Kansas City, MO. This clinic is adjacent to a very busy and large primary care clinic, Meritas Gashland. Meritas physician clinics are affiliated with North Kansas City Hospital and our Physical Therapy & Sports Medicine Departments. North Kansas City Hopsital's Physical Therapy Team is noted for one-to-one patient treatments schedule for 60 minute treatment blocks. In addition, our patient satisfaction is noted as "five stars" through Google Reviews and over 96% patient satisfaction scores through Press Ganey surveys. Our team at this location consists of 9 PT's, 2 OT's and 1 SLP, creating a multi-disciplinary team that
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Dr. Scott Walsman, MD is an ophthalmology doctor who practices in Jersey City, NJ. He is 40 years old and has been practicing for 12 years. Dr. Walsman is affiliated with Barnabas Health Jersey City Medical Center and Saint Barnabas Medical Center.
Looking for an Ophthalmology Specialist? We found others matching your search, to help you compare.


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A team led by New Zealand scientists think they've found a vital clue to developing the first treatment for Huntington's Disease.
The debilitating neurological disorder can lead to extensive loss of control over bodily movement, dementia and psychological disturbance and eventually premature death.
It directly affects one every 10,000 people and there is no treatment for it.
Now, international researchers led Professor Russell Snell and Dr Renee Handley, of the University of Auckland's School of Biological Sciences and Centre for Brain Research, have pinpointed one of the very earliest changes in the brain that results in the disease.
Their work, just published in prestigious scientific journal Proceedings of the National Academy of Sciences, identified elevated levels of the chemical urea in the brain of a transgenic sheep model, which matches those of human brains affected by Huntington's.
Because it is known that neurons are lost in the brain before any symptoms of Huntington's show, the long-term research focus of the group has been to determine the first biochemical change caused by the gene that leads to the cell death.
Results from the five-year study show that the Huntington's sheep model, which is symptom-free but carries the mutant form of the human huntingtin gene, have the same increase in urea in the brain as the post-mortem brains of people who have died of Huntington's.
Urea is a naturally occurring chemical in the body, produced from ammonia. Both are normally excreted as they are toxic to cells.
"Genetic disorders of the urea system result in increased levels of ammonia and urea, causing severe neurological symptoms," Handley said.
The findings clearly pointed to brain urea, or ammonia, as a therapeutic target for Huntington's disease.
"What gives us hope is that treatments already exist for reducing urea and ammonia in the brain.
"These could very simply be tested in Huntington's disease, initially using our sheep model."
Snell was part of the international team that identified the gene mutation that causes Huntington's in 1993.
"The next step, which we have already begun, is testing how we might treat Huntington's disease with this knowledge.
"It is a terrible disorder, devastating for families and our focus is on discovering a therapy as quickly as possible."
Meanwhile, the first drug targeting the cause of Huntington's disease was found to be safe and well-tolerated in its first human trial.
University College London (UCL) scientists have been monitoring a human clinical trial of a drug that successfully lowered the level of the harmful huntingtin protein in the nervous system.
After more than a decade in pre-clinical development, this first human trial of huntingtin-lowering drug began in late 2015, with sponsorship by Ionis Pharmaceuticals.
The trial involved enrolling 46 patients with early Huntington's disease at nine study centres in the UK, Germany and Canada.
Each patient received four doses of either IONIS-HTTRx or a placebo, given by injection into the spinal fluid to enable it to reach the brain.
As the phase trial progressed, the dose of IONIS-HTTRx was increased several times, according to the ascending-dose trial design.
"The results of this trial are of ground-breaking importance for Huntington's disease patients and families," said Professor Sarah Tabrizi, director of University College London's Huntington's Disease Centre.
"For the first time a drug has lowered the level of the toxic disease-causing protein in the nervous system, and the drug was safe and well-tolerated.
"The key now is to move quickly to a larger trial to test whether the drug slows disease progression."


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Liner Notes – Connie Stevens, Paul Ackerman (2). Photography By – Gene Trindl. Mastering SID Code: IFPI L901. Mould SID Code: IFPI 2U6A. Other Versions (5 of 5) View All.
Honky Tonkin' song from the album The Hank Williams Songbook is released on Aug 2012. The duration of song is 01:44. This song is sung by Connie Stevens.
On this page you can listen to songs from The Hank Williams Songbook (Connie Stevens). The most listened, most popular singers, albums and songs are at soundbae. Next Song: You Win Again. The Hank Williams Songbook.
The Complete Hank Williams is an award-winning 1998 box set collecting almost all of the recorded works of country music legend Hank Williams, from his first recorded track in 1947 to the last session prior to his untimely death in 1953 at the age of 29. While a number of live and overdubbed songs are excluded, the ten disc collection contains 225 tracks, including studio sessions, live performances and demos. Among those 225 songs are 33 hit singles and 53 previously unreleased tracks.
Randall Hank Williams (born May 26, 1949), known professionally as Hank Williams J. or alternatively as Bocephus, is an American singer-songwriter and musician. His musical style is often considered a blend of Southern rock, blues, and traditional country. He is the son of country music singer Hank Williams and the father of Hank Williams III, Holly Williams, Hilary Williams, Sam Williams and Katie Williams.
Actor/singer Connie Stevens was born Concetta Rosalie Ann Ingolia on August 8, 1938, in Brooklyn, NY. Coming from a highly musical family (both her parents were jazz musicians and her brother was a drummer), the up-and-coming singer changed her last name to Stevens after her father's stage name (Teddy Stevens). At the age of 16, she was singing in her first group, the Three Debs. Stevens stopped issuing recordings in the mid-'60s (after issuing such further albums as From Me to You, The Hank Williams Song Book, and As Cricket), and focused primarily on acting, starring in such movies as Grease 2, Back to the Beach, and Tapeheads, among countless others. In addition, Stevens has developed her own cosmetic skin care product line, Forever Spring, and in the late '90s, she opened the Connie Stevens Garden Sanctuary Executive Day Spa in Los Angeles, CA.
|A1||Hey, Good Lookin'|
|A2||I Can't Help It (If I'm Still In Love With You)|
|A3||Your Cheatin' Heart|
|A4||Jambalaya (On The Bayou)|
|A5||A Teardrop On A Rose|
|A6||You Win Again|
|B1||Settin' The Woods On Fire
Written-By – Nelson*, Rose*
|B2||I'm So Lonesome I Could Cry|
|B3||Cold, Cold Heart|
|B5||Nobody's Lonesome For Me|
|B6||May You Never Be Alone|
|CCM-149-2||Connie Stevens||The Hank Williams Song Book (CD, Album, RE)||Collectors' Choice Music||CCM-149-2||US||2000|
|W 1460||Connie Stevens||The Hank Williams Song Book (LP, Album, Mono)||Warner Bros. Records||W 1460||Canada||1962|
|WM 8111||Connie Stevens||The Hank Williams Songbook (LP, Album, Mono)||Warner Bros. Records||WM 8111||1962|
|WS 1460||Connie Stevens||The Hank Williams Song Book (LP)||Warner Bros. Records||WS 1460||US||1962|
|HS 11312||Connie Stevens||Songs Of Hank Williams (LP, Album, RE)||Harmony||HS 11312||US||1969|


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Situs Poker Indonesia is another form of poker that a lot of people keep on playing as it is interesting to try with. To follow the rules and know the mechanics of the game can have a big chance of winning this kind of game. There are various types of situs poker, that every player can choose and would love to play. A player needs to make sure that they are with a reliable website and reputable enough to trust by a lot of people.
Various Situs Poker Indonesia
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Bandar Q Situs Poker. It is also a game that is using also domino cards. Wherein this can be only be played by two people. Each player will be given 2 domino cards and then the highest value of the card is 9. When a player combines the two domino cards and the total is 10, this is equivalent to zero. This is just like playing with the Adu q, the online difference is that the number of domino cards they are using with.
There are a lot of interesting games every player can try and explore. But make sure that before risking money in playing online casinos an individual knows how to determine if it is fake or original. It is one of the riskiest in playing online, especially for a player to enjoy the game they need to deposit money.
Wouldn’t be unfathomable if there was a way to deal with makes sense of how to prevail at online poker. Imagine the lifestyle of truly making a few bucks by playing what is apparently a PC game which you can play in your shower robe or apparel. Believe it or not thousands are truly getting a living by prevailing at online poker in this way can you? If you watch ESPN, by then you have seen the improvement of online poker especially Texas Holder. The flood and improvement of poker all around is attributed by a dark player named Chris Money-creator bewildering the world when this dark first year recruit won the best and most pined for poker rivalry on the planet by winning the 2003 World Series of Poker and reserving the astonishing prize of 2.5 million dollars.
Countless would be Chris Money-creators have gone to online poker as far back likewise with desires for being the accompanying gigantic victor. One of the huge purposes behind the conspicuousness is traditional people essentially like Chris transforms them as a matter of course on TV by winning one of those weeks many communicate poker events and ended up one of a creating once-over of poker big shots. One of the key differences among poker and surely understood world class games like football, tennis or golf, is paying little regard to how much fitness you may have, you can’t just show up and plan to battle with the aces of that game paying little mind to whether you are skilled. In any case, in poker anyone willing and prepared to put the area charge gets an opportunity to sit next to each other with the top experts seen on TV standard.
Online poker rooms are a staggering spot to hone your poker aptitudes and test your abilities and karma in a live real situation against other certifiable people. Online poker rooms can similarly empower you to discover qq poker indonesia playing procedures by review other gifted players from all around the world who play online. It is a brilliant idea to watch a table you’re excited about playing at for quite a while and make sense of the bent of the players before you plunk down. The higher the table staked the practically certain it is that you will face better skilled players so you have to play adroit and at table stakes that fit your ability level and comfort. One huge insight in playing poker is to complete your work. This may moreover mean you may need to place assets into a book or two and read up on the fundamentals of the game and speculations behind betting techniques before playing for authentic money. Endeavour to pick an online poker website which offers engaging store rewards which they will offer to another customer at the time you first sign up. Fundamentally every poker room will offer a type of store reward to get you to pick them as your poker site.
After the arrival of the Net right into the life of individuals, it had actually changed their lifestyle in every feasible way. An immense modification has been noted in the gaming market too. Considering that the development of casino online, a huge variety of casino poker gamers have finally stop their previous betting venue alternative whereby I imply land-based casinos. Most of them do not favor checking out to land-based gambling enterprises any longer in order to play online poker video games. This is rather noticeable too, besides with online casino online, it is not required for you to bother getting dressed, obtaining a ride to the area and gathering some other online poker players just to begin with your casino poker experience. If you like to rely upon a casino site internet site to meet your poker hobby or enthusiasm, you do not need to wait outside of any type of gambling establishment waiting on the opening up hr to find.
As many of the gambling establishment websites come 24/7, you can have a fantastic and also pleasing gambling establishment experience whenever you want. Simply by having accessibility to the Net link, you can remain in touch with your favorite casino internet sites all the times. The benefits and also prizes that are supplied at on the internet casinos are no less than what traditional poker locations include to their players. As a matter of fact, it is also possible for you to play online poker at a number of casino site internet sites at the same time also without leaving your home, which is no question outstanding! Furthermore, a substantial competition has been observed among the online casino poker web sites out there and also each of them are attempting their finest to find up with something that would aid them to obtain much more energetic players.
Normally, they supply big rewards and also prizes as incentives with an intent of attracting increasingly more gamers to their internet sites. So you can capitalize on such a solid competition between them and attempt obtaining some substantial prizes and also pots. However, take into consideration a whole lot while selecting a situs judi qq online terpercaya web site for you and also take your time looking into about the casino poker websites you are aiming to rely upon. Omaha Poker is easy to find out however a lot harder to master, the betting rounds resemble those in Holdem but the primary difference in Omaha Poker is each gamer is dealt 4 cards not 2 similar to Holdem. This is the most effective poker video game to make cash, especially when you have a small bankroll. For all of these reasons, people are changing to online poker web sites today when it pertains to playing poker online or any type of various other online casino games.
Over bet is another internet betting site propelled in 2010 and its online poker room is on the consolidation gaming system. The supervisory crew has been in the poker business for quite a long time. All new poker players will get 100% coordinate to $600 store bonus and section into the everyday first investors $500 free roll competition. New poker players that store over $1,000 will get VIP program that incorporates quicker cash outs, restrictive substance from the Over bet group geniuses, and significantly more.
The Over bet store bonus clear at a pace of $1 of bonus cash cleared per 75 VIP focuses. Players acquire 6.5 VIP focuses for each $1 in rake or competition expenses. Over bet utilizes the contributed rake technique. Over bet players store bonuses discharge in $5 increases and the store bonus lapse following 90 days. Additionally, players can trade their VIP focuses at a pace of 200 VIP focuses for $1.It’s prescribed to play extremely tight with your hand choice at the no restriction poker, fixed breaking point poker, or pot limit Omaha $0.50/$1 tables or higher to clear your store poker bonus rapidly. Playing exceptionally tight at the poker tables will enable you to make back the initial investment or have a little win rate to clear your store bonus and https://qqpokerdomino.club/category/domino
In the interim, there are just some online club that at present acknowledge PayPal stores that numerous players are not natural that they can utilize their records to play. Various online poker destinations are thinking about the execution of conceding PayPal poker and the every one of the individuals who do is relied upon to bring definitely up in the following couple of months. Right now there are in excess of ten differing nations that award for PayPal poker stores, with all the more thinking about the execution. Greece, France and the UK are just a couple of the nations that will concede you to utilize your PayPal record to fund your online poker stores. As more individuals discover the ease of utilizing this procedure of store it is ensured to state that a lot more nations will in the blink of an eye add PayPal stores to their online poker financing alternatives.
Unmistakably there are a couple of complexities in an online poker room and a live poker club. Most of these differentiations are viably watched and direct to the general poker playing open. In any case, various contrasts are not discernible or evident while playing poker online. The genuine contrast between online poker and live betting club poker is the cards and how they are passed on to the player. There are unprecedented focal points to playing in a live club as the trustworthiness of the game is now and again put into request, since the modifying, the overseeing and the ‘eye in the sky’ keeps the game sensible and makes it about hard to deal that uprightness. In any case, online poker needs a critical number of these protections for the player, in that a PC program achieves the reworking and overseeing of the cards.
Along these lines, a perception of how online poker goals programming framework capacities is earnest to any player that needs to place money into an online poker account with desires for structure a bankroll and getting the cash for out. Just in light of the way that, if you perceive how the item capacities, you can be ensured that you are not presented to unlawful undertakings by various players, the poker room or even the item to cheat you out of your merited money. All online poker regions use an assortment of a subjective number generator to make a revised deck. Disregarding the way this may have every one of the reserves of being satisfactory, numerous events throughout the latest a serious extended period of time, propositions revamping figuring’s were broken and in this way permitted swindlers an opportunity to abuse the game and various players. The exposure of the cheats by affected poker regions induced them to make additional qq poker online terpercaya estimations to neutralize attempts at cheating and plotting. Those estimations would control the action at a table to ensure that one player can’t win every single hand simply like the case in the Absolute poker humiliation. In that event, a lone player won about 98% of all hands played in an essential challenge, beating a couple of hundred distinct players. Numerically it is hard to win each presents a challenge, and thusly the poker regions acquainted programming with shield this from happening.
Likewise, the online poker regions programming ventures can perceive a player who may scheme with another player and thusly the program can modify the consequence of the cards to shield that player from winning. This identical programming can recognize poker bots as well. Because of a poker boot, the item will make into idea every individual move by a player and cleverly balance that with choose whether the player in truth is a boot or a certified person. The issue with these additional poker computations is that they normally impact a capable player’s ability to dependably cash. By the day’s end, it is the equivalent than if a live merchant were setting the deck to empower a particular player to win or power a player to lose.
In case you have noticed cautions about betting in live gambling establishments, this post is going to inform you about the hazards linked to actively playing poker on the web. It can be necessary for athletes to understand how they might be cheated by websites and will as a result prevent this from happening when you are much more mindful.
Below are a few variables you can preserve at heart before you start playing online:
Look into the website as well as its reputation: It is crucial that you just surfing the net to get poker websites that have a great track record. This can make sure that they offer you your rightful winnings. Appearance out for web sites like Greatest Guess, Heaven Poker, Poker Stars, Paradise Poker and Celebration Poker as they are considered reasonable and fast with their transactions. Visit the website http://livesport88.com/.
When you are not cautious and merely visit any website to perform poker, chances are that you simply will not only shed the amount of money you might have put in for signing up, they will not give you winnings either. Smaller sized internet casinos rip-off players by declining to help make their obligations promptly. This is extremely harassing for the participant, who has presently dropped so much income.
be sure the website’s shuffling algorithm continues to be audited by trustworthy firms: All customers taking part in internet poker should be aware the shuffling that proceeds. Now each site features a fundamental shuffling algorithm that has been made and given into the process. Also called the arbitrary figures power generator, this is when most modest casino houses work their scams. Players find you burning off large amounts of cash ever since the algorithm was designed to benefit the casino.
When sites would like to promise their clients their surgical procedures are definitely legitimate, they get credited review companies to look at their algorithm formula for virtually any indications of nasty play and publish this mix up algorithm criteria on the webpage to exhibit athletes they indicate company. Many of these reputed web sites even get a betting license from your regulatory payment, that means they have to keep to the rules and regulations established straight down with the company if they need to maintain operating their demonstrate.
Many individuals claim to make a full-time living playing online poker, nevertheless to do this you need to win well over 50percent of your hands. So is it possible can people truly make a living playing texas hold’em online to discover, we require comparing offline poker to playing casino poker online. Well, we already recognize that people do make consistent revenues making use of only offline texas hold’em, so it stands to factor that people should likewise have the ability to win online poker at the exact same price, as long as the two video games are not as well different. Firstly, in offline texas hold’em video games you are able to review tell and look individuals in the face when they play. This is not feasible in online poker, you merely cannot check out player’s worried reactions or any kind of informs they might have, rather you need to rely on the choices they make.
Nevertheless, you can still check out individuals by previous plays they have actually made and noticeable wagering patterns they have. If you do not have impassivity, or you have problem in reviewing people, this can in fact be an advantage. Secondly, there are virtually three times as numerous hands dealt per hour in the online globe of casino poker. This does not alter the game way too much tactic wise, with the exception of the speed at which the video game is played. Usually, people that make earnings with texas hold’em with their computer, stand to make even more money than they can in an offline video game. Third, in dominoqq online poker you can use many tools while you play the game that will inform you the chances you have of winning your hand. These devices are merely difficult to make use of in an offline game of casino poker. Few offline video games would allow you to have a laptop available while you are resting at the table.
Finally, there are texas hold’em events and cash money games readily available online that would certainly be difficult in the real life. Things like mini cash money video games video games that make use of ridiculously small blinds or substantial competitions would certainly be a headache to organize in the real world. It is certainly feasible for people to play and win sufficient casino poker on the web to call it a living – this holds true – nonetheless it is a various kind of individual that would certainly prosper in the online globe. Abilities that include a deep understanding of the game, and also the capacity to review people generally are not required in texas hold’em online. Rather, various abilities are required to be successful. Contrasted to offline texas hold’em, a different character kind is needed in order to earn a living playing poker online.
In the realm of on the web gambling club poker, manners are very essential. Exactly how you will unquestionably work at the gaming decorations may influence not only your individual experience, yet the encounters in the different gamers that you will surely be with. In this way, it is important to comprehend the imperatives of betting behavior for web games, similarly as progressively conditions. The extraordinary factor would positively be that the online texas poker programming application handles significant amounts of components for you legitimately. You can’t erroneously, or purposefully, work a long way from modification in on-line texas poker, for instance. In this way, that isn’t something you have to worry about. String having a fabulous time is besides something which online gambling club poker programming application licenses you to keep away from. All of that separated, despite the fact that, you may in any case find a decent arrangement of components of web based wagering that you deal with without anyone else. In the event that any kind of among those parts separates, you can get an unfavorable encounter for all included. In this way, permits examine a couple of for all intents and purposes one of the most indispensable tips to keep up complete smooth alongside pleasurable for everybody.
Web based Betting Area Associations Concerns
From the outset, a generous trouble that different on the web players have is connection concerns. When you are utilizing a steady moving Internet connect, or requesting your web webpage web interface by endeavoring to do various focuses at precisely the same time, you may see without anyone else isolating from your wagering work area ordinarily. That factor 2 fundamental inconveniences. The primary issue is, without a doubt, you may maybe go down hands or, maybe, fight to return to proactively playing the contenders you stay in any sort of methods, depending on exactly how generally you discrete and furthermore explicitly what the requirements are for that web webpage you will unquestionably be utilizing. Some net sites, as a picture, permit boundless reconnects, anyway simply give you with a specific assortment of sacs to reconnect. Different other individuals will surely show you out of the game absolutely subsequent to having a particular measure of disengage.
Utilize the Exchange Reason for the Poker Web site appropriately
The second stress, which you will maybe not have entirely contemplated, would unquestionably be that the various different people at the table interest to anticipate the alternative of sacs at whatever point that you discrete. That may make your game long just as tiring for everybody, just as similarly not urging gamers to achieve the doable to aggregate their parcels as fast as gamers at various different other work areas in the degrees of contenders, that strike be proactively playing an incredible arrangement significantly more hands much faster. One greater necessity of on the web wagering behavior is continually to take warning. Each judi poker domino qq online indonesia club poker online web webpage supplies you with a picked size of time to take your adjustment. When you are different entrusting at different destinations, it is plausible to miss your modification altogether.
Probably the most widespread route for U.S. poker participants to perform poker is via an online poker us web site. You will discover playing online poker is attractive. What is superior to getting the lodging of your very own property, most loved chair, this game in the T.V., when you play poker? By doing this, you must just expose the site’s item, help make your store and also you are ready to engage in.
A few locations offer online poker incentives whenever you recruit. You will be making the initial retail store and also the prize typically coordinates the measure of a store. You don’t get it instantly, in light of the point that it can be gone into what exactly is known as your Benefit bank account. A lot of times, prior to getting your incentive, you should perform a specific measure of palms, controlled by that certain Livesport88 site. The predetermined measure of palms that you will be necessary to play typically is not going to go beyond the amount you will engage in, when you are not kidding about playing to succeed. Apart from the Indicator-up rewards, there is a Reload prize that may be once in a while offered as soon as the gamer can make added shops. In addition, you have the Referrer reward presented when you get distinct athletes to participate with the poker internet site. 5 of your best poker locales who do have the prize motivator is; Full Lean Poker, Poker Celebrities, Total Poker, Athletics Reserve Poker and Players Only Poker.
The 5 spots referenced previously mentioned are US poker locations that loved United States athletes to participate. Poker competitions are yet another invigorating portion of the online poker. They may have turned into well-known. You can find the Single-dinner table tournaments, similarly known as ‘Sit-and-Go’ competition. The poker activity commences when every one of the players happen to be positioned at the table. When this occurs you will find the Multiple-desk competitions. This video game begins in a certain time, assigned from the poker area. A big area of the contests is played out as ‘freeze outs’. At the conclusion of your day, when you are from coins, you might be out from the online game. One other kind performed is definitely the “Rebury’. It is possible to repurchase in to the activity with more French fries when you have outside the get-get in the video game. After having a certain time establish, as an example, the principle 60 minutes, at that point you may never yet again repurchase in and yes it becomes the ‘freeze outs’ kind of online game. Poker Celebrities can be a top web site for events, in view of the incredible settlement outs. The Sporting activities Book Poker tournaments have reduced stakes, with significantly less completion, which might assert yourself on the away from probability that you are currently a student poker games that should possess the competition expertise.
The Majority of the people like to perform with the Gambling games through web since it is the most secure approach to manage gets all assortments of games. In unequivocally absolutely a similar time it is the perfect method to put the agreeable bets. Through web it is definitely not hard to put down bets with your contrary player, in perspective on this variable a large portion of the web betting destinations offer you dumbfounding decisions. All of the games included with higher completion of developments rather than those games are getting phenomenal effects, for instance, graphical limits.
In the event you choose dominoqq online you will get not too bad experience, the multiplayer games moreover gave phenomenal characteristics with the objective that you can instantly pick the most fitting matches to play. Online club games besides sponsorship to win liberal cash, at unequivocally correctly a similar time you never again need to spend impressive money as the store. Online is the perfect spot to experience dumbfounding betting features and it is the astonishing stage to play with a combination of structures games. Online is the spot to acquire the attributes of betting, the vast majority of the card sharks single out the web to set the bets at the gainful structure, in general web have incredible store procedure, the smart payouts in addition updates the comfort level of their part.
Significant procedure to find help:
Pattern setting development empowers the Effectiveness of those poker games. Online is the ideal stage to play with and revel in the remarkable bewildering games, the poker made to thoroughly sheds most of the drawbacks of the normal poker and it is the better preoccupation choices. Going before detail to perform, you may realize bits of knowledge in regards to the Judi Online. With the assistance of web part can without a doubt get to genuine games. From how you may get splendid progressions despite gaming fitness, would it be a smart thought for you to go up against a couple of issues while making the web bets you can get rules from the prodigies, the authorities also supplies experiences to make the agreeable bets on soccer and various games that are online. Online offer best betting games appeared differently in relation to physical games. In web betting, the game is much of the time well known and this can be a round of the ball turns which found on the round wheel together with the seven openings.

domain: hobby


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A 200 year-old single arch, cast iron bridge by Thomas Telford.
The Craigellachie bridge spans the river Spey at the village of Craigellachie, is the oldest cast iron bridge in Scotland.
The bridge was built by the famous engineer Thomas Telford between 1812 and 1814. It features two sets of mock-Medieval turrets, standing 15 feet high on each side of the river.
It's possible to cross the bridge on foot, but the best views are from the walkway of the modern replacement.
The content of many of our web listings is provided by third party operators and not VisitScotland. VisitScotland accepts no responsibility for (1) any error or misrepresentation contained in third party listings, and (2) the contents of any external links within web listings ((1) and (2) together hereinafter referred to as the "Content"). VisitScotland excludes all liability for loss or damage caused by any reliance placed on the Content. The Content is provided for your information only and is not endorsed by VisitScotland.


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Kabbalah and the Bible I
What is Kabbalah? How does Jewish mysticism explain light and darkness, the brokenness of the world, the Messiah, and the Creator himself? Do these understandings coincide with or contradict Biblical truths? Were Jesus (Yeshua of Nazareth) and Paul (Saul of Tarsus) Jewish mystics? Why is the Word of God like “burning fire” that cannot be contained, as the prophet Jeremiah wrote? How did Jewish and Christian mystical thinkers, artists, philosophers, and scientists — from Rabbi Nachmanides to Sir Isaac Newton and from Isaac Luria “the Lion” to Mirandola the Renaissance man — approach this secret knowledge? Join Dr. Gruber on an exciting journey in considering these big questions by looking at original source texts of Jewish mystical tradition and the opinions of notable scholars.
- Sessions 32
- Duration 6
- Language English
This is a place where our students and faculty converse about course content.

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Maw 27 Gorff to Gwen 1 Gorff / 10am - 4.30pmlleoliad: Elan Valley Visitor Centre
Cycling is a great way to see a lot more of Elan.
Sad 23 Hyd / 10:00 - 16:00lleoliad: Elan Valley Visitor Centre
We’re very excited to announce that, working with the Cambrian Mountains Initiative, we’re holding a Cambrian Mountains Food, Drink and Craft Fair on the 23rd of October from 10am – 4pm. The event is free, and no booking is required. Come along and find some fantastic, locally produced food, drink, and crafts!
For more information email firstname.lastname@example.org
Gwen 29 Hyd to Sad 30 Hyd / 14:00 - 18:00lleoliad: Pen y Garreg Dam
Halloween has arrived at Pen Y Garreg!
Do you dare to venture along our spooky woodland trail and inside a haunted Pen Y Garreg dam? (This is a family friendly activity!)
Make your way up through the woodland keeping an eye out for the pumpkin markers. On each marker is a letter. Use these letters to create a password which will get you past the gatekeeper and into the dam.
Walk though Pen Y Garreg dam to the central tower where you can collect a Halloween treat, then continue your journey through the dam, down through the woodlands and back to your car.
Sad 8 Ion / 7.15am onwards for Registrationlleoliad: Elan Valley Visitor Centre
Annual Walking (or running) CHALLENGE EVENT held across OPEN AND CHALLENGING UPLAND TERRAIN in and around the Elan and Claerwen Valleys.
The route is waymarked in parts but MAP READING SKILLS ARE REQUIRED.
Either 13 or 20 mile courses are available. Entry Fee & Kit Check apply.
Start Times : 8.30am for 20 mile route Walkers; and 9.00am for 13 mile route and ALL RUNNERS on both routes.