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Researchers from Brown University investigate “Attenuated Psychosis Syndrome”, proposed for the DSM-5, finding that they “could not identify any patients who clearly met criteria for APS alone in our sample. Psychotic experiences appear to be common in outpatients and represent nonspecific indicators of psychopathology. Diagnosing APS in the community could result in high rates of false-positives or high rates of APS “comorbidity” with other nonpsychotic disorders, leading to the increased use of antipsychotic medications without clear need. Therefore, the clinical utility of adding APS to the diagnostic system remains highly questionable.”
Gaudiano, B., Zimmerman, M., Prevalence of Attenuated Psychotic Symptoms and Their Relationship With DSM-IV Diagnoses in a General Psychiatric Outpatient Clinic. Journal of Clinical Psychiatry, Online October 2, 2012
Shocking! I didn’t think it possible to cast a net too wide where the DSM was concerned. Maybe the authors are just APS deniers?
Their denial surely indicates that they’re suffering from a terrible personality disorder and they need drugs to help them see their denial as a sure sign of their mental illness. Someone needs to help them! And I’m sure that we could find something in DSM-5 that would substantiate their terrible illness!
I only wish the Australian government would realise what this research is showing. They are currenlty rolling out massive early psychosis centres around the country, at a cost of billions of dollars, all to prevent psychosis. And of course drugs are a part of that treatment. This video clip, shows what they classify as someone at risk of psychosis. If that is not 99.9% of the population I do not know what is. What is even scarier is that MOST mental health professionals seriously fully support this role out and the diagnosis. There is outrage that the American Psychiatric Association has declared publically that it will not be in the DSM5. But they have also said that it will not stop them from treating the disease, as they know that it works, and we supposedly can’t wait for the rest of the world to catch up!!!

domain: news


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Leigh-on-Sea, Essex: F. Lewis Ltd., 1946. First edition. Original cream linen boards (10 7/8 inches tall), uncut, original dust jacket. Gentle offsetting from the plates, mild wear and faint spotting to original dust jacket. A near-fine copy. Item #777
'IF THOU WILT ENTER INTO LIFE, KEEP THE COMMANDMENTS" Limited edition of these bold illustrations of the Ten Commandments—complete in the scarce original dust jacket. The Ten Commandments appear twice in the Old Testament, in the books of Exodus and Deuteronomy. Dorothea Braby was a prominent illustrator, perhaps best known for her work creating book illustrations for the Golden Cockerel Press. She prepared an illustrated title page and 11 black-and-white plates, each graced with a fine Roman numeral printed in red. The plates are preceded by a series of five epigraphs (including Matthew 19:17 and Matthew 5:19) and an explanatory Foreword, emphasizing the commonality of essential truths across the spectrum of world religions: "For the express purpose of illustrating the universality behind all true teaching, texts have been incorporated also from the wisdom of Ancient Egypt, Krishna, Buddha, Lao Tsze and others. Buddha's own five commandments are almost identical with the Hebrew law." The Ten Commandments are each captioned in the plate with a quotation, with the sources footnoted on the final leaf. A limitation statement: "This edition of 'The Commandments' is printed on mould-made paper and limited to 1025 copies of which 1000 only are for sale."

domain: library


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This week’s Throw Back Thursday focuses on a 5-3 come from behind win at the Larson Ice Center. The Wings got off to a slow start trailing after the 1st 1-0. The beginning of the 2nd was more of the same and Brookings was able to make it 2-0. 6:40 into the 2nd Ronnie Hein put the Wings on the board with assists from Bjorn Sigurdarson & Kyle Haak. Just 3 minutes later Tanner Okeson would get his first goal of the evening on the power play knotting the game at 2 all. Assisting on the Okeson goal was Michael Soucier. Brooking would add a goal late in the 2nd to retake the lead going into the 3rd. In the 3rd it was all Aberdeen, Kyle Haak would get things started just 5 minutes into the game with assists from Ronnie Hein & Sigurdarson. Tanner Okeson would add what would be the eventual game winner to his total for the night once again on the power play. Assisting were Zac Goodrich & Sigurdarson. Austin Heakins would add the empty netter with an assist from Brendan Riordan to cap off the Wings 5-3 victory! Andrew Shortridge got the win in net making 20 saves on 23 shots!
Aberdeen will be looking for a similar result this Friday and Saturday night at the Odde vs. Brookings! Game times are 7:15pmand the doors open at 5:30. Friday is FREE KIDS FRIDAY! All kids 12 and under will receive a FREE ticket with the purchase of an adult ticket at the door. Friday’s Corporate Sponsor is Pioneer Seed, and its SKATE WITH THE WINGS!!! Bring your skates and join the team on the ice after the game! Saturday is the annual Christmas food & toy drive! Bring a non-perishable food item or unopened toy and receive $2 off admission at the door! All food and toys will be donated to a local charity for help with the holiday season! Saturday night you can also get in on $15 bar stool seats upstairs in the corporate area by calling Aaron at (605) 380-5852! We might also have some alumni here throughout the weekend!!!

domain: sports


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Yesterday I went to see Nowhere by Nilo Gallego and Chus Domínguez, and also by Luminita Moissi, Mirela Ivan, Angelica Simona Enache, Mariana Enache, Julián Mayorga, Jonas Mekas, Claudia Ramos, Raúl Alejos, Ana Cortés and Óscar Villegas. This work, in my opinion, is from all of them, each one is different, and this parity is just one of the many wonders of this theater piece. I could not like it more, I burst into tears, but they weren’t tears of grief but of pure joy and delight at the image of exiles, migrations and difficult worlds lived with real flesh and blood through singing and even laughter. I really liked the fact that the beautiful promises that Jonas Mekas made on the video from 11/7/2017 (“the small, the small, the personal”, spoken as he did, with a trembling but firm voice) were all fulfilled. And also that his authorship did not command or impose itself as the most important one on stage: the simple phrases of his diary from exile opened in a historical time (the Second World War) continuing on to the present of migrations brought by the phrases of the performers on stage. There was no importance given to the author’s name. The selected fragments from the newspaper talked about their refusal to go to the army in America because they’d fled Europe as “animals flee” from the war. They also talk about the nose bleeding while crossing the continent at war; about not wanting to work on Saturdays in a factory, and about snow in NYC. And then, a gate opens at the back of the scene, and it snows in Madriz. The snow is everywhere. Magic. I really liked the way the four actresses on stage sang, played and cooked, fearlessly, no imposition, no gesture detached from their presence. The experience of spending more than half of this piece without understanding their language (Romanian), and the moment (WONDERFUL: the best I’ve ever experienced in my life on stage in terms of verbal form) in which they change to the shared language, Spanish-Castilian, because Julián Mayorga (Colombian) and Claudia Ramos (from her accent she seems to be from the peninsula) were sitting at the table. The verb tenses were all over the place giving a liveliness to their speech, the way of saying, with full communication and many incredibly precise details. Green paper, white paper, small paper and large paper are different versions of the NIE (Foreigner Identity Number), that you could get in a place called Padre Piquer: if any Spanish-speaker is able to understand it better than anyone who does not speak the language, this person would lie. These words seem to mean specific things but the real meaning comes from the ones who use them and do not have the nationality. I really liked the music, the way Julián Mayorga interrupted the songs to explain things about them. Things such as the meaning of Tolima, or the difference between the European waltz, which traveled to America, and its American version: the pasillo. I was very pleased to see the display on the ground and the collection of each object in a truck with metal pieces that were for sale and other pieces from the world (a cardboard head, a dog, an accordion, traffic signs). I was neither bored nor amused, I just looked on with pleasure, I was very comfortable with and in this work. I still feel the joy and emotion I felt when leaving: these were very real because the transmission itself was very real. No show, no abuse, misuse or use of others by others (directors for example). No hierarchy, no money. The courage to stage material that could have been manipulated in a thousand ways; the success of each subject in action, including the spectator, will maintain its Agent, that is, its ability to think (the language) and act, in its own way, individually and together (as the language is more or less from all of them when the domain is removed). In short, I can’t explain, what goodness, beauty and justice. Holy crap! It is a must-see!
Text by María Salgado published in her blog Globo rápido.

domain: artistic


Don't forget, ALL airguns are assembled and zeroed prior to dispatch, and delivered direct to your door!
Made from a strong polymer composite that is both extremely lightweight and strong and finished in tactical military design, this stock by Blackhawk is a fine addition to any serious shooters arsenal. The fully adjustable rear end fitted with a rubber recoil pad makes this stock comfortable to fire for shooters of all sizes.
Perfect for those shooters looking to upgrade their firearm and take their shooting to the next level or even build their own rifle from scratch, this stock maintains the high quality that Blackhawk are known for.
- Shape : Axiom Tactical
- Action : Short
- Colour : Black
Pellpax offers the best delivery service in the UK, with weekly deliveries on all airguns across England and Wales (Unfortunately we can no longer deliver to Scotland), and mail order deliveries on all other items.
As an RFD we can deliver air rifles and air pistols direct to your door. See our guidelines on what ID is required.


Live Updates: Russia invades Ukraine
Ukrainian President Volodymyr Zelensky on Sunday accused Russian troops of targeting civilians, including children, and called for an international investigation into the conflict.
“What they are doing in Kharkiv, Okhtyrka, Kyiv, Odessa and other cities and towns deserves an international court. We document their crimes. And there would have been many more of these crimes without our brave defenders,” Zelensky said in a video address posted on his Facebook page.
“You have to call a spade a spade. Russia’s criminal actions against Ukraine show signs of genocide. I spoke with the UN secretary-general about it,” he said, arguing that Russia should be stripped of its right to vote in the UN Security Council.
Zelensky said there was “not a single facility in Ukraine that Russian troops would consider an unacceptable target.”
In the capital Kiev, residents awoke on Sunday to find the city still firmly under Ukrainian control, despite two massive explosions some 30 kilometers south of the city lighting up the sky overnight.
Fighting broke out in the streets of Kharkiv, Ukraine’s second largest city, after Russian forces entered the city
The Russian Defense Ministry has previously said it was targeting military infrastructure only, saying in a statement: “The Armed Forces of the Russian Federation do not strike towns and villages, they take all measures to save the lives of civilians”.
But Zelensky said on Sunday: “They lied that they would not target the civilian population. Since the first hours of the invasion, Russian troops have been hitting civilian infrastructure.
“This is terror,” he added, while Ukrainian Prime Minister Denys Shmyhal said Russia was committing “war crimes”.
“They fight against everything and everyone,” Zelensky said. “They are [hitting] kindergartens, residential buildings and even emergency vehicles. They use artillery and missiles against entire residential blocks where there has never been a military infrastructure. Many Ukrainian towns and villages are surviving in conditions that we previously had only during World War II.”
Learn more here:


In an overcrowded city, the government has found a way of fixing things - move nearly everyone out to country for a while, then tear down the whole city & rebuild it to a new plan. Of course, everyone could not go; some had to stay back to help.
When the time came for crowds to return, they had a surprise waiting...
Fact sheet.First published: Antipodean SF, #127 (December 2008).
Download full text.
Related: Stories of Mark Tremble.


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Allegiant adds nonstop service from New Orleans to Tulsa
If you have family in the Sooner State or you're looking to explore more of the Great Plains, Allegiant Air has some good news for people in New Orleans.
Airline officials said nonstop service to Tulsa, Oklahoma, from Louis Armstrong International Airport will begin May 26 and end Oct. 16.
Allegiant is kicking off the summer travel season with 22 new routes, service in three new cities and a free airfare giveaway.
"Expanding to new cities and offering new routes is a great way for us to grow our brand of convenient, low-cost travel for millions of travelers," said Jude Bricker, chief operating officer for Allegiant.
Airline officials are calling the offer "$1 Million Summer" and the goal is to offer flights to cities that are typically not serviced. The airline will expand its low-cost, nonstop service to Sonoma, California, Evansville, Indiana, and Albuquerque, New Mexico.
As part of the summer campaign, the airport will give the first 22 travelers to book their flights on each of the new routes a refund of their round-trip airfare.
More information about Allegiant and its services can be found online.

domain: travel


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Hello everyone! Vinterd here taking a little switch from doing the reviews to bring you some very exciting news. Reeder (boss-man, if you will) and I have compiled a list of bands their albums that have been released this past year that we’ve enjoyed, and we decided to not do what everyone else is doing and do a countdown. Instead, we’re leaving it up to you – the viewers! Down below you’ll find a poll where we’ve put albums that we enjoy. You can vote at your discretion and see how many other people out there also love the album that you voted for. So go down and vote your eyes off! Here’s to another fantastic year of metal!
VOTING IS OVER. RESULTS HERE

domain: hobby


The All Progressives Congress (APC) has described as a product of poor thinking and deliberate mischief the statement credited to the
so-called PDP Media Watchdog asking President Muhammadu Buhari to resign because of his comments over his age.
In a statement issued in Lagos on Wednesday by its National Publicity Secretary, Alhaji Lai Mohammed, the party said if the authors of the statement had understood simple English, taken the pains to engage in deep thinking and contextualized the comments, they would not have rushed to the press to ask the President to resign.
”What President Buhari was saying, which was lost on those who issued that jejune statement, is that only his love and passion for the country could have made him, at his age, to come out of retirement to seek the office of President, over 30 years after he presided over the affairs of the country.
”For 16 years, Nigerians gave the PDP the benefit of the doubt to move the country forward, but instead, the party put Nigeria in reverse gear at a high speed, spinning it towards a doomsday that was only averted when Nigerians showed the PDP the red card. This is what necessitated President Buhari to continuously seek the country’s highest political office, so he can help put the country on a forward march again. Nothing else matters, not for him the excitement of an office he previously held and the quest for personal accomplishment.
If the country had been well managed, President Buhari will not at 72 be crisscrossing the whole world seeking solution to Nigeria’s problems, it said.
APC said within three weeks of his inauguration, President Buhari has succeeded in returning Nigeria to the comity of nations, to such an extent that world leaders are now so eager to engage him on how to assist his country in key areas, including security and the fight against corruption.
”Within three weeks of President Buhari’s inauguration, he had done what the PDP government could not do in six years: Invigorate the fight against Boko Haram by rallying a regional and global front against the terror group. Today, the US has pledged to give $5 million
for the fight against Boko Haram, in addition to other materialsupport. This is apart from the support that has been pledged by the
G-7 for Nigeria’s efforts to quell the insurgency.
”Thanks to President Buhari’s shuttle diplomacy, the Multi-National Joint Task Force (MNJTF) that the PDP government could not bring together for all of six years is ready to deploy next month, while the President has ordered the release of $21 million to facilitate the establishment of the headquarters of the force in N’Djamena, Chad.
”Since assuming office about three weeks ago, President Buhari has visited Chad, Niger, Germany and South Africa, winning support and friends for Nigeria all over again and returning the country to the comity of respected nations. Those who were put off by the PDP government’s resort to politicizing the fight against Boko Haram – even as the insurgents grew stronger – are now joining President Buhari to battle the terrorists. In no distant future, the results of his tireless efforts will begin to show.
”On the domestic front, President Buhari has been handling pressing issues far away from the klieg light, and his efforts to assembly a first class team to implement his change mantra, which he is personally driving, are continuing apace. We in the APC, and we are sure most unbiased Nigerians, are very proud of President Buhari and the vigour he has shown in governance, the kind of vigour we did not see in the immediate past administration that was presided over by a far younger man,” the party said.
It said only anarchists and non-democrats will ask a President who has not spent one month in office to resign, adding: ”It rankles when those making these calls are from the ranks of the party that failed to avail itself creditably in 16 years.”
APC said it has deliberately refused to join issues with the PDP, which has been issuing a series of insipid press statements that showed clearly that the party is not ready to provide a robust opposition to the APC-led federal government
”For the umpteenth time, we say that the PDP and its satellite bodies must realize that in order to be relevant, credible and to make the necessary impact, they must pick on real issues and articulate them intelligently, rather than latching on to trite matters. This very amateurish display won’t get them anywhere,” the party said.
PDP MEDIA WATCH-DOG TELLS BUHARI TO RESIGNS
Press statement from PDP Watchdog. Read below…
The PDP Media Watchdog has reacted to the statement credited to President Muhammadu Buhari in which he declared and admitted that age will limit the rate of his performance in office as President of Nigeria.
The group while reacting to the statement on Wednesday June 17, 2015 said the APC and President Buhari are gang of hypocrites and liars. “The PDP is again vindicated by this confession from President Muhammadu Buhari and many more that are yet to come.
Nigerians will recall that during the presidential campaigns, the PDP and other well meaning Nigerians complained on the choice of sponsoring Pa. Muhammadu Buhari as Presidential Candidate of APC and the effect it will have on the country when it comes to managing the affairs of a multi dimensional nation like Nigeria, but the APC and its leaders said that age is just a number”.
The PDP Media Watchdog again reminded Nigerians of their earlier statements on the need for the people of this country to challenge the numerous inconsistencies of this APC administration and call on President Muhammadu Buhari to resign immediately to save the country of this four years of motion without movement because according to the group, all they have done since May 29th is that Pa. Buhari and the APC has hit the ground sitting instead of running as they promised.
“It’s barely three weeks into the administration of President Muhammadu Buhari and his age is already telling on him, so, what will happen to Nigeria in the remaining 1,440 days of this government. It’s better to find a black goat in the day time rather than looking for it in the night and this is why we are asking President Buhari to resign now because Nigerians will not entertain further excuses of why the APC cannot deliver on their campaign promises”. the group said.
The group also gave another example of how President Buhari’s age is affecting his performance and reminded Nigerians of how he disgraced the country in a world forum when he referred to the President of Germany as President of West Germany. “Nigerians saw this all along during the campaigns but could not resist the broom stick voodoo that the APC used to hypnotize the people. Nigerians will also recall that this same Pa. Buhari could not remember the complete name of His Vice Presidential Candidate and even the full name of his party, the All Progressive Congress (APC) under which platform he was contesting and instead referred to it as the All Progressive Confidence during the campaigns. How long will a nation like Nigeria, the giant of Africa remained under this hypnosis of the APC” the group queried.
Finally, the Watchdog urged the people of Nigeria to wake up to the challenge and resist this daylight robbery and blackmail of the All Progressive Congress (APC) and demand the immediate resignation of Pa. Muhammadu Buhari and call for another election to elect a more competent and vibrant Nigerian to lead to the people to the Nigeria of our Dreams.
For: PDP Media Watchdog


According to Twitter, William Hill is offering NBA Finals series odds on both San Antonio vs. Miami and San Antonio vs. Indiana. The Heat are -270 vs. the Spurs who are +240. SA is -250 vs. the Pacers (+210). Miami owns a 2-1 series lead over Indiana heading into tonight's Game 4 matchup. San Antonio just wrapped up a four-game sweep of the Memphis Grizzlies.


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Stamp Recipe: LaLaLand, SU Short and Sweet
Paper: Basic Black, Gable Green, Welcome Neighbor 6x6 DSP
Ink: Basic Black, Gable Green, Melon Mambo, Chocolate Chip, Blush Blossom
Accessories: Aqua Painter, Scallop oval punch, Polka dot grosgrain ribbon, Black 1/4" gingham ribbon, misc eye glass sticker, cording, Crochet Fleurettes II, ms adhesive pearl, Big Shot scalloped circle dye
Card size: 5x5
I love books. I love reading. I always have and probably always will. I like stories that take me away and I like stories that teach me about other cult...


Start control circuit diagram of frequency sensitive rheostat for three phase motor
The frequency sensitive rheostat is applied to start the control circuit of the wound rotor asynchronous motor as shown in the figure below. The starting process is as follows: turn on the power switch QS first and then:
Press the start button SB1, connect the contactor KM1, connect the motor to the power supply, and connect the rotor circuit into the frequency sensitive rheostat RFs in series. At this time, the value of the equivalent resistance and reactance of the frequency sensitive rheostat is very large, which limits the starting current and improves the starting torque. After the time relay KT is connected, after a period of time, its normally open contact of delay closing is closed, and the intermediate relay KA is connected. At this time, the motor has been started and accelerated for a period of time, and the equivalent resistance and reactance of the frequency sensitive rheostat are also very small. Ka’s dynamic closing contact closes the contactor km2, and its dynamic closing contact shortens the frequency sensitive rheostat, and the start-up process ends.
TA in the figure is a current transformer, its primary side is connected in series with the motor stator circuit, and its secondary side is connected with the thermal relay fr. In the process of starting, Ka’s normally closed electric shock shortens fr’s heating element to avoid thermal relay misoperation due to long starting process.
Starting control circuit diagram of rotor series resistance of three-phase wound motor
In order to limit the starting current and improve the starting torque, several starting resistances or frequency sensitive resistors can be connected in series in the rotor circuit. This paper will describe the starting control circuit of series resistance in the rotor circuit of three-phase wound motor, and its circuit diagram is shown in the figure below.
The working principle is: after the power switch QS is closed, more than KT3 of time relays kt1 and kt2 are connected, and their normally closed contacts of delay closing are immediately opened, so that KM1, km2 and KM3 will not be connected temporarily, so that when the motor stator winding is started with rated voltage, the starting resistors RI, R2 and R3 are connected in series in the rotor circuit to limit the starting current and improve the starting torque.
When starting, first press button SB1 to connect undervoltage relay KAV, its dynamic contact is closed. When the power supply voltage is seriously reduced or the circuit suddenly loses power, KAV’s dynamic contact is disconnected to protect the motor. Then press button SB2 to connect the line contactor km, and the stator winding of the electric motor is started with rated voltage. In the control circuit, the auxiliary contact of KM is opened, the time relay kt1 is powered off, its normally closed contact of delay closing is closed for a period of time, the contactor KM1 is connected, and the starting resistance R1 of motor rotor circuit series connection is cut off. At this time, the motor only operates on the artificial characteristics of starting resistances R2 and R3 in the rotor circuit, and continues to accelerate.
After the contactor KM1 is connected, its dynamic contact is open, which makes the time relay kt2 power off, its normally closed contact with delay closing is closed for a period of time, and then the contactor km2 is connected, and the starting resistance R2 in the motor rotor is cut off. The motor operates on the artificial characteristics with only resistance R3, and continues to accelerate. After the contactor km2 is connected, its normally closed contact is open, the time relay KT3 is powered off, and its normally closed contact with time delay is closed for a period of time, so that the contactor KM3 is connected, and the starting resistance R3 is removed. So far, the rotor circuit of the motor has no external resistance and operates on the natural characteristics. This concludes the startup process.


Abu Dhabi: Over 12,000 film enthusiasts enjoyed a night filled with movies and live entertainment as Tropfest Arabia successfully launched its inaugural edition on Friday.
The one night event was the latest installment of the successful Tropfest, billed as the world's largest short film festival, which originated in Australia.
Organised in partnership with twofour54 and presented by MBC2, the festival was a part of the month-long Yasalam series of events organised in conjunction with the Formula 1 race that will take place from November 11 to 13.
In keeping with its unique tradition, the 12 films chosen out of entries submitted from across the Middle East and North Africa (Mena) each incorporated the Tropfest Signature Item (TSI), Star.
"I'm amazed by how many people turned up...everything completely exceeded my expectations not just in terms of films but also the set-up...we leapfrogged the first decade of Tropfest in Australia. But of course, we plan to continue building on all that has been achieved. There are always several things that have to be worked out, but I believe it will just keep getting better and better," said John Polson, founder of Tropfest.
Fruit Bowl trophy
In addition to beating 11 other hopefuls for the coveted "Fruit Bowl" trophy, Iraqi filmmaker Jasem Al Jabbouri (Flock of Stars) received $12,500 (Dh45,900), a trip to Los Angeles to meet top film executives and a trip to Australia to be a judge at Tropfest Australia 2012.
"I'm feeling so many different emotions right now, it's hard to say how I feel...its been an amazing experience participating in Tropfest Arabia, even though there were some challenges before I was able to come to Abu Dhabi...I can't wait to meet the film executives... this will be an amazing opportunity and hopefully I'll receive some great advice on how I can enhance my career further," he said.
The evening event also saw the attendance of many notable Arab celebrities, including renowned Egyptian actor and Tropfest Arabia co-director Ahmad Helmy, Egyptian actress Mona Zaki, UAE filmmaker and one of the event's judges Nayla Al Khaja.
Tropfest Australia 2011 winner Damon Gameau was also in attendance.
The top three films at Tropfest Arabia
1st place: Flock of Stars by Jasem Al Jabbouri (Iraq)
2nd place: The Smile by Lubna Saeed Al Amoodi (UAE)
3rd place: They Say by Ahmad Gazal (Egypt)
Best Actor: Ali Salloum
Best Actress: Dana Dajani
For more information about the festival please visit www.tropfestarabia.com


Problem Solving Standards
IPPS supports specific recognised standards in how problems are resolved. These principles and high-level standards are agreed by Senior Managers in various industries and disciplines across the globe:
- For multiple problems, the problem solver will identify “cause and effect” relationships and will then pinpoint the core issues represented in the problem situation.
- Resolving a complex multi-tiered problem will have adaptive and corrective actions to provide a complete solution.
- Information gathering will be done based on the Divergent/Convergent thinking model.
- When a problem situation is experienced, the problem solver will endeavor to find the cause first before taking action. The professional problem solver will always ask “Why?”
- Every incident or problem will have both a technical cause and a root cause. You need to first establish the technical cause before you are be able to identify the correct root cause(s).
- Identifying the most appropriate stakeholders and information sources will always precede information gathering.
- Identifying the most specific object and most specific fault will come at the start of the technical cause analysis.
- Specifying the detail of the incident/problem/solution will be based on factual information arranged in a factor analysis framework.
- Hypotheses will be tested on paper before any actions are implemented.
- Any decision to be taken will be preceded by a proper stakeholder analysis.
- Evaluation of options/action and alternatives will be systematically screened against the solution or decision requirements.
- Before a decision is implemented, risks for implementation will be considered.
- Risk analysis will be based upon the relationship between risks and likely causes of that risk.
- All analyses will be rounded off with an appropriate action plan to implement the next step actions.
- All actions to be taken will be screened against the original objective of the problem-solving exercise.


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Gilbert and Sullivan in Rocket City!
Gilbert and Sullivan in Rocket City explores the famous G&S operas in today’s world by creating a production in and about Huntsville. This show combines some of G&S’s best-known pieces such as Three Little Maids, The Matter Trio, and Poor Wandr’ing One with brand new, clever dialogue by G&S lover and expert, Jaie Deschene. Tailor-made for Encore Opera Huntsville, the three little maids transform into three little engineering nerds from UAH. The nerds wander through Rocket City building robots, spaceships, and, of course, looking for love. Hilarity ensues.
Fri, April 9, 2021
7pm- Trinity United Methodist Church- Wesley Hall
Sat, April 10, 2021
2pm- Trinity United Methodist Church- Wesley Hall
Sun, April 11, 2021
7pm- Burritt on the Mountain
Did you miss the G&S Pre-performance discussion with
Click the the button below to watch it!
Who are Gilbert and Sullivan and why do we care about their works? Learn more about these hilarious collaborators and their many operas, as well as how Opera Huntsville will showcase their work in Gilbert and Sullivan in Rocket City. Led by Gilbert and Sullivan savant Jaie Deschene.
Who were Gilbert and Sullivan?
The world of Gilbert and Sullivan - what was life like in Victorian England?
What are their notable works?
Tropes in G&S Works
Calhoun Chorale, under the direction of Granville Oldham, will be the chorus for the production! For more information Please visit their website!


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What does a narcissist with low self esteem say?
Why was an old man absolutely not tempted by my good looks during the days I was on the street, when I was young and beautiful
providers review the clients in this exclusive view from the hooker’s perspective
Not everyone is what they do, but liars deserve to be known as such and do not waste time trying to get the truth
I do not know how to win friends and influence people. I can’t figure out how I lose friends and alienate people, but I do. Lol.
Fun isn’t always a team sport. For some guys they want the fun to be about them and only them and they are willing to pay for the privilege of not having to even pretend to care about another person.

domain: sociology


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One of the outside walls at Festival Foods in New London was brought down Wednesday, May 28.
The controlled removal of the wall was part of Festival Foods’ expansion project taking place.
The store is adding around 2,000 square feet to the liquor department.
The customer service area is also being redone.
Completion of the project is expected in August.


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"Working with Cynthia was just incredible. The images turned out so fabulous and every time I look at the photos on our wall I just feel so happy and grateful to have them."
LIKE WHAT YOU SEE?
YOUR STORY STARTS HERE
And no two stories are alike. Each family I work with has its own unique story and deserves its own unique photographs - images that stand the test of time in both form and function. Portraits that are created to remind you of your happiest moments and spark joy in your soul every day as you simply walk down your hallway or flip through your album together.
Atlanta Family & Newborn Photographer
Cynthia Spivack Photography is an Atlanta area family photographer also specializing in maternity, newborn, and baby photography as well as beautiful portraits of motherhood. Based in Atlanta, Georgia, and serving the surrounding areas including Alpharetta, Milton, Cumming, Roswell, Marietta, Acworth, Kennesaw, and Buckhead.


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The June issue of FOCUS Magazine is here! We have lovely articles featuring Rachel Magic and Janjii Rugani. Also, Belen interviews our group member and blogger, Lakaluka. And Siobhin Shippe “photo bombs” Curtis Trevellion! It’s a super issue and I hope you all enjoy it.
Also featured are the winners of the FOCUS Photography Fair challenge winners! If you missed them, you get to see them here!
Angela Thespian ♥

domain: entertainment


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Seriously, is there anything more complicated than a womanʼs body? Especially during childbearing years, it can seem like something new is happening every day. For some women, the menstrual cycle is predictable, coming and going on a pretty even keel; others, however, experience physical and emotional turmoil of the Jekyll-and-Hyde kind. Either way, whenever something new or different is felt, thereʼs always the question
lurking in the backs of our minds: is that normal or am I pregnant?
These six symptoms of pregnancy are classic, though they donʼt always represent a pregnancy. Sometimes the daily trials and tribulations of ordinary life can bring on symptoms that may make you think you're pregnant. Donʼt let these symptoms fake you out, but do have them checked out if they persist.
- Youʼre Late
According to the textbooks, the average menstrual cycle lasts 28 days, but this timeline isnʼt etched in stone. There are no textbook women and no textbook menstrual cycles. The stresses of everyday living can affect hormones in a way that speeds up the cycle or slows it down. Both good stress - new love, new job, dream vacation in Paris - and bad stress can affect it. Anytime life is going through a change, it is not unusual for it to inﬂuence the menstrual cycle.
Again, stress takes its toll on oneʼs energy level so changes in the outside world, especially stressful changes, affect the quality of our sleep. Sometimes lingering fatigue is the only symptom of a low-grade infection or an early sign of something more serious. Take the day off, eat something healthy, watch a funny movie, and crawl into bed early. If a few nights of good, relaxing sleep donʼt clear up the fatigue or if additional symptoms develop, do see your doctor as soon as possible.
- Food Cravings
Pickles and ice cream may be legendary on the pregnancy menu, but food cravings can signal a nutritional deﬁcit. The body craves the foods that supply the missing nutrients. Someone whoʼs never liked tomatoes, for instance, but ﬁnds themselves popping juicy little cherry tomatoes like popcorn, is likely to need the nutrients supplied by the tomato. She may be pregnant, but she may also just need to improve her diet.
- Canʼt Keep Food Down
Stress and dietary imbalance can lead to nausea. A binge of potato chips and chocolate is as likely to leave someone as queasy the next morning as a binge of martinis...or even a glass or two more of wine than a personʼs used to. If nausea lingers, do see a doctor; nausea can be a signal of a number of other issues.
- Tender Breasts
The menstrual cycle changes over a womanʼs lifetime and can cause the breasts to feel tender even when that hasnʼt been a typical symptom of menstruation or premenstrual syndrome (PMS). A more vigorous exercise class or running an extra mile can irritate the breasts, too. Unusually amorous lovemaking can leave tender lingering memories, too.
- Crazy Mood Swings
Sometimes they seem crazy, but sometimes theyʼre justiﬁed. Loss of a loved one, new home, money or job woes, an approaching birthday, or sending the last kid to school can take an emotional toll on even the most stoic individual. Most women can wear a pretty, public smile when needed but a good cry behind the scenes can be a very healthy way to release emotional tension, even if you didn't know it was there.
One of the best things about being a woman is our fabulously complex body. Itʼs dynamic - it changes a bit every day. Celebrate it, enjoy it, but try not to let every new sensation come with hope of a pregnancy. The stress of such intense anticipation can sometimes be counter-productive.
Source: "What Are Some Common Signs of Pregnancy?" National Institute of Health. 19 Mar 2013. Web. 16 Sept 2013.

domain: medical


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Great assortment of deals I always look forward to when my weekly notification comes in as it gets me all excited about a new adventure to be had!
Look outside your box... Options, it's all about the options. Expanding my horizons. Trying something new to do or new to see or new to taste.
Great! I'm always looking for a travel deal and travelzoo app is one of the first I go to.
Very good app....planned three or four vacations from this app already and haven't let me down yet 👍👍👍
Great travel asset! Use this to find the best trips at the best prices. You just have to be a little flexible!
Great for travel deals! Loads of options and deals are well picked up. If you can be a little flexible, you can save lots of money.
- User experience enhancements
- Performance improvements
- Bug fixes
Amazing hotel deals for tonight + no credit card needed on selected properties!


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Imagine a place where ocean views meet mountain peaks, and luxury seamlessly blends with nature. Welcome to Naturally Pacific Resort, your coastal haven in Campbell River, BC. Perched at the crossroads of lush forests, majestic mountains, and the Pacific Ocean, our boutique hotel invites you to escape into Vancouver Island’s greatest outdoor playgrounds.
With 100 beautifully appointed rooms, a luxurious spa, upscale dining, and a world-class 18-hole golf course complete with a virtual driving range, our resort promises unforgettable experiences and genuine hospitality.
Campbell River is a gateway to adventure, boasting eco-adventures, renowned salmon fishing, and wildlife encounters. Let your journey begin at naturallypacific.ca. Explore, indulge, and create cherished memories at Naturally Pacific Resort.
Opening May 2024


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Paris Hilton and Lindsay Lohan's MySpace profiles breached
While the not-so-publicity-shy stars probably won't mind, and none of the photos are all that racy (except for the one of a fully dressed, provocatively posed Hilton in a tanning booth), there's a lesson for us all in this social network privacy flap du jour.
"Anything you upload to a public Web site is not private; it's public. Even if you think it is password protected," says Jeremiah Grossman, chief technology officer at White Hat Security, a Web application security company. "That's the bottom line."
The problem has been fixed so don't bother trying to replicate it. But the breach resurrects the debate over whether the notion of privacy is outdated in a world where you party too much at an event and the next morning an embarrassing photo is up on your friend's Facebook page.
Valleywag blamed data portability, the concept underlying the sharing of data between social networks and other sites.
However, according to MySpace, it had nothing to do with data portability and everything to do with Yahoo using "deprecated mobile APIs."


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Over the past few years, Jeff Retro has been putting his name on the electronic music map. Known for his electrifying residencies in Las Vegas, Jeff is pricking ears of tastemakers, including Musical Freedom head Tiesto. Making his debut on the esteemed imprint, Jeff Retro releases the new single Isle Of Man. Isle Of Man is an energetic ensemble that draws on traditional Scottish roots with its distinct bagpipe melodies taking charge amongst climactic drums and powerful percussion. Sure to triumph across dancefloors and festival arenas alike, Isle Of Man is destined to be a hefty dance anthem. Excited to take Isle Of Man across the globe, Jeff Retro explains: “I poured my heart into creating this song and I was so incredibly humbled when Tiesto played it at Tomorrowland. The response so far has been overwhelming and I can’t wait for the rest of the world to hear
it.”Quickly becoming a regular and popular name across the Las Vegas scene, Jeff Retro holds a residency as a headliner at the most prestigious clubs in the city including no.3 and no.9 ranked clubs in the world, Omnia Nightclub, Hakkasan Nightclub & WET Republic Ultra-Pool. Having supported the likes of Calvin Harris, Martin Garrix, Zedd, Steve Aoki, Kaskade, and Nervo, (who have all given the rising producer their seal of approval) Jeff Retro is a name that is starting to turn heads. Taking his sound worldwide, Jeff Retro and his ever-growing reputation show no sign of slowing down.


The Big Questions in Science and Religion, by Keith Ward (Templeton Foundation Press). Of the many excellent overviews of current issues in the interaction of science and religion, this one is readable and balanced, a good start for a broad audience. A theologian conversant with scientific issues, Ward covers ten questions, from the big bang to revelation and divine action.
Only if he blames Romney personally for not voluntarily paying more. As I said in Romney's defense a while back, the problem isn't that presidential candidates with plenty of money aren't willing to pay their taxes. The problem is that their taxes are too low.
In order to write about the inner workings of a private prison, journalist Shane Bauer took a prison guard position at a Louisiana prison for four months, at $9 an hour. The prison is operated by Corrections Corporation of America, whose CEO made $3.4 million in 2015, nearly 19 times the amount paid to the director of the Federal Bureau of Prisons. During Bauer’s time as a correctional officer, the federal Department of Corrections temporarily took charge of the prison due to a rash of stabbings among inmates. Thirty-four percent of prison guards suffer from posttraumatic stress disorder, a rate higher than that for Iraq and Afghanistan veterans. Correctional officers commit suicide two and a half times more frequently than the general population (Mother Jones, July/August).


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Search Result for Appl Systemt Online De
Appl Systemt Online De documents. You have searched the Appl Systemt Online De from Free Online Auto Repair Manuals Download blog archives. If you can't find what you are looking for then try your search again using different words.
File Name: Polyethylene oxide polypropylene oxide polyethylene
Description: Review polyethylene oxide polypropylene oxide polyethylene oxide block copolymer surfactants in aqueous solutions and at interfaces thermodynamics structure.
Last Accessed date: Fri, 14 Oct 2016 07:38:00 GMT
Download Source: www.sciencedirect.com
Download Link: Polyethylene oxide polypropylene oxide polyethylene

domain: chemistry


Each Chandan-Whittle piece is an ode to India and its heritage, a celebration of the colour and chaos intrinsic to life there. For founder and designer Kam Chandan-Whittle, this is a chance to honour her family’s Indian roots whilst celebrating local artisans and their handicraft skills. This striking cushion can completely switch up your room: layer it on a couch or use singly on a bed. It features a delicate feathery pattern in teal, yellow and white and is hand screen printed by a womens’ co-operative in Karur, South India, that ensures fair wages and economic independence for its workers. It is finished with beautiful, handmade ties that end in multi-colour tassels.
30 x 122 cm
100% organic cotton
Hand screen printed
Cover care: Machine wash cold, with a gentle detergent
Ramya Cushion Cover
0.00€ incl. VAT, shipping extra, non-EU customers save 19%.
A striking cushion with two different coloured sides made from handwoven organic cotton. The pink side has a delicate geometric pattern woven into the fabric, whilst the back is a vibrant yellow. Handmade tassels in pink and yellow finish off this piece.
50 x 50 cm
Handwoven organic cotton
Insert not included
Care instructions: Machine-wash on a cold, gentle cycle, with like colours. Iron at medium setting.


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With the fast developments in technology and the push for a greater focus on hygiene and sanitation, it comes as no surprise if the robotics segment in the food tech industry is gaining traction. According to research conducted by Meticulous Research, this segment is expected to grow at CAGR of 11.6% from 2021 to 2028, reaching valuation to about $2.2 billion by 2028 globally.
The study, titled “Food Robotics Market by Type (Articulated Robots [SCARA, Six-axis Robots], Delta & Parallel Robots, Collaborative Robots, Cartesian Robots, Cylindrical Robots, Portal Robots), Payload, Application, End Use, and Geography — Global Forecast to 2028” showed that many F&B companies have begun investing in the space. Digital technologies such as robots and automated production lines are seen in more food manufacturing facilities. Opportunities from emerging economies are also driving growth in the sector.
Robots also minimise human interaction during the production process, therefore reducing instances of contamination. Cleanliness and food safety have been top considerations in the industry as a result of the COVID-19 pandemic.
Articulated robots comprise majority of the market share, with these types incorporated in food processing companies in particular. These enable flexibility, high-load capacity and operation consistency, leading to fewer disparities often caused by human error. Palletizing and depalletizing systems also dominate the segment.
Companies that operate in the dairy sector are utilising robots more in order to roll out high-quality products while reducing costs. Sensors, vacuum tools and grippers are among the tech adopted by dairy businesses.
The Asia-Pacific region is developing at a significant pace, but traction is also seen generally across the world.


everythingpossible - Fotolia
While Amazon S3 data leaks have dominated headlines in the past, the misconfigured security controls that caused them aren't exclusive to Amazon. In fact, misconfigurations can pose a risk across all public cloud platforms, which means enterprises should be careful to prevent them.
Some of the biggest cloud security threats come from the improper setup or configuration of cloud access controls and permissions.
"The No. 1 issue is not properly securing access credentials," said Fernando Montenegro, analyst at 451 Research. For example, there is the tendency to use authentication methods that are not as secure as they could be, especially for admins.
A lack of multi-factor authentication (MFA) poses a risk that is exacerbated in cloud compared to on-premises data centers. If an admin has a weak password in a traditional environment, a hacker would still have to get into the data center to use it. In the cloud, though, that access can happen remotely.
"The downside of failing to [use MFA in cloud] is that, if someone can grab your root account, the sky is the limit," Montenegro said. "They can literally create resources and new accounts, which is a serious problem."
Sharing isn't always caring
To avoid cloud security threats, it's best to go back to the basics. For example, enterprises should be especially cautious with open file shares, which are typically too accessible, said Jay Heiser, analyst at Gartner. Most organizations use a large number of SaaS apps and don't always known which support sharing, as those decisions are often made on an ad hoc basis, he said.
Jay HeiserAnalyst, Gartner
This is why cloud access security brokers (CASBs) -- such as those from Skyhigh and Bitglass -- now play a more prominent role in the enterprise. CASBs have become more like firewalls, in the sense that they're viewed as tools for baseline protection, Heiser said.
"If an organization wants to control open file sharing, the CASB tools are the most efficient way to do that," he said.
Another risk that enterprises commonly ignore involves sharing code for application development. It's now common practice to put code on a shared site, such as GitHub, but sometimes, that code can include access credentials or other sensitive information.
"If anyone downloads that, they have your secrets," Montenegro said. "One developer could accidentally blow away your infrastructure."
Know your responsibilities
To minimize cloud security threats, enterprise IT teams first need to know exactly where their providers' responsibilities end and where their own begin. In other words, they need to be familiar with their providers' shared responsibility model.
The level of responsibility an enterprise has varies, however, depending on the cloud model: SaaS, PaaS or IaaS. Each of those different approaches puts an increasing level of configuration and security burden on the customer, said David Monahan, managing research director at Enterprise Management Associates.
To learn more about users' vs. providers' responsibilities in a SaaS vs. PaaS vs. IaaS deployment, check out this brief video.
Follow provider best practices
Another rule to avoid cloud security threats, and the misconfigurations that cause them, is to adhere to your provider's recommendations and best practices.
"People talk about problems with AWS S3 buckets, but that's another case of people going against the provider recommendations," Montenegro said.
All major cloud providers offer guidance and documentation to securely deploy their resources, but users don't always follow through. AWS, for example, pushes for best practices, such as not using root accounts for projects and enabling two-factor authentication, but when enterprises prioritize speed over caution, they often overlook those recommendations. So, be sure to review your cloud provider's security best practices thoroughly and apply them as much as you can.
"Security is normally a function of competency," Heiser said. "If organizations don't know what they're doing, they tend to do the wrong thing."


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I woke up in the morning today… ok… was woken up by the constant kicking by Tashvi to play with her. I took her to the park with swollen eyes and tossed her a few times in the air and felt deep rest listening to her constant laughter and the glitter in her eyes which wanted more… and as I passed through the park, a thought passed my mind and well…..
What kind of world have we brought our children in. We are fighting purpose-less no-holds barred fights, which seem endless. The people of one’s own country are mercenaries killing in the name of religion without any demands… so, where’s the motivation coming from ? Is it an act of religious revenge, someone’s personal revenge, political motivation to defame a community or party before elections, plain hatred or just fun.
Whatever it is, these misled gentlemen don’t realize that they are helping no one but the enemies of India and they are destroying a country in which they intend to live forever. A country which has evolved as a powerful nation in it’s 61 years of existence, a country that provides us (all religions alike) safe haven, a country that recognizes all men as equals. But, these gentlemen’s acts are a lose-lose situation for everyone… And they and their community loses the most.
They destroy India’s image, society and culture, and jeopardize their own safety as well. After all, they too would not like to live in a world of chaos, civil war and army running around tanks in streets.
They are destroying the respect of the India for the whole community by doing this in the name of religion. The Muslims of India are celebrated and respected by each and every Indian in the names of Dr. Kalam, Zakir Hussain, SRK, Aamir, Azhar, Pathans and the list is endless. These aimless boys are jeopardizing the respect for each and every individual mentioned above and their religion in the minds of India.
What they are creating is fear… a fear which made me think twice before entering the FR mall on Sunday and making me reject the idea of going to a mall on October 2nd holiday. And the fear factor is gripping the nerves so tightly that I felt that our children will have to listen to war tales every day while growing amidst war, death, crime and a plummeting economy. Did we do right by bringing her to life only to live a life in fear.
The above thought passed through in a minute or so and I squeezed my little 7 month old tightly walking towards home with loads of sadness in my eyes. And with all her naughtiness, Tashvi showed her irritation and scolded me for trying to crush her… A single action of hers is enough to sends a happy vibe through my body and I entered home with a big smile, tossing her again wanting to hear her pure laughter one more time, while hoping for a better India for her.


HCS Control Systems (HCS), a Glenrothes, Fife, UK-based specialist manufacturer of engineered mechanical, hydraulic and electrical systems for the subsea oil and gas sector, received an £8.5m investment.
Maven Capital Partners invested in the company via a Buy-in Management Buy-out transaction (BIMBO) alongside the Simmons Parallel Energy Fund. Maven and Simmons have each provided £4.25m of equity funding. An additional investment came from Front Row Energy Partners, a consortium of upstream industry specialists which invests in high quality energy service companies.
HCS intends to use the funds for business growth expanding into new overseas markets.
Established in 1997 and today led by Brett Lestrange, CEO, Business Development Director Tony Kitchener, COO Kenny Balfour and a CFO Neil McGuinness, HCS provides an integrated service offering which includes design, engineering, specialist welding and fabrication processes. The company is now opening of an Aberdeen base,
Its global blue chip customer base includes GE, Cameron, Schlumberger and Expro.


Apple iMac A1418 21.5" Desktop MD093LL/A Nov 2012, i5 2.7GHz 8GB 1TB OSX 10.11
- Condition: Tested Working - Seller Refurbished. What do we refurbish? We make sure everything in working order and reset to factory setting. In very good condition.
- Contents: Destop Monitor, Power Cord.
- Manufacturer: Apple
- Manufacturer Part No. iMac A1418 MD093LL/A
- Memory Type: 8GB Ram
- Capacity: 1TB HDD
- Processor: Core i5 2.7GHz
- Graphic Type: Integrated/On-Board Graphics
- Optical Drive: N/A
- Operation system: OSX 10.11 EL Capitan
- Microsoft Office: MS 2011 installed
Please notify that there will be no CDs included. Desktop Monitor only, no accessories. No Mouse or Keyboard include.
The Apple iMac A1418 21.5-inch desktop brings all the benefits of a Mac to your home or office desk. The MD093LL/a runs on the Mountain Lion operating system, and it is an excellent computer for editing. With its patented stylish design, silver color, and powerful processors, this Apple Mac provides excellent quality. Whether you're new to Apple products or have been a lifelong user, this sleek and attractive computer has everything you need at the touch of your fingers.This 21.5-inch iMac is powerful, quiet, and easy to set up wherever you need a beast of a computer at your disposal. Released in late autumn 2012, this quad-core computer was designed with suitability for high-end use in mind. This Apple computer also offers a Core i5 processor for fast handling of multiple computing processes, and it runs at a 2.70 GHz processing speed. The 8GB of installed RAM work in conjunction with a whopping 1TB hard drive to provide its users with a performance engine that is up to the rigors of heavy use. This Apple iMac is ideal for editing media files or for storing large amounts of data. It would make a great gift for anyone with games to program, piles of data to organize, or music and movies to collect.With a resolution of 1920 by 1080 pixels, the screen allows you to see crisp color in rich detail. This means it is great for both basic web browsing and intense media streaming. Catch up on sports games, binge watch your favorite Netflix shows, or check out tutorials on YouTube without missing a moment of movement. The iMac is also a great choice for a number of creative functions. Its integrated microphone, built-in speakers, and built-in web camera make recording audio and video a breeze. This is great for users who have blogs to upload or songs to tune in Garageband. This Apple computer also has a jack for headphones and optical digital output for audio, allowing you to connect speakers and other accessories. With four USB ports and two FireWire ports, you can connect your phone, iPod, or any other mobile device without having to swap between ports.This desktop includes a wireless keyboard and mouse, so you can get set up and ready to go within minutes of opening the package. You can also easily connect a second monitor to the iMac after purchasing a VGA cable. The packaging was designed thoughtfully with care and protection in mind, and the wireless keyboard and mouse will keep your desk space clutter-free. You can easily connect other accessories to this iMac to make your computing even easier.With an installed video memory of 512MB and a NVIDIA GeForce GT 640M graphics card, this Mac guarantees a smooth and detailed visual quality. Whether you want to play games or kick back and watch a movie, you won't miss a single color, detail, or pixel of the action.
Product Family iMac
Processor Type Intel Core i5 3rd Gen.
Processor Speed 2.70GHz
Number of Cores Quad-Core
Bus Speed 100 MHz
Screen Size 21.5in.
Expansion Slots SDXC card
Hard Drive Capacity 1.02TB
Hard Drive Rotation Speed 5400RPM
Hard Drive Interface Serial ATA III
Hard Drive Type SSD
RAM Technology DDR3 SDRAM
Installed RAM 8GB
RAM Max Supported Size 16GB
RAM Memory Slots Qunatity 2 x 204 Pin SODIMM
Installed Cache Memory 6MB
On Board Graphic Processor NVDIA GeForce GT 640M
Max. Video Resolution 1920 x 1080
Installed Video Memory 512MB
Video Outputs Mini DisplayPort
Audio Input Integrated Microphone
Audio Output Headphones, Optical Digital Output
Networking Type Bluetooth, Integrated 10/100/1000 Network Card, Integrated Wireless LAN
Height 17.7 in.
Width 20.8 in.
Weight 12.5 lb.
Form Factor All-in-one
Release Date November, 2012
Exterior Color Silver
Other Features Built In Web Camera


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Sunday, March 18, 2012
When the Beatles took off in America in 1964 it sent a shock wave through the music business. Teenage girls weren't the only ones screaming and crying. Tears were also being shed by American musicians who saw the British Invasion groups sucking up all the record sales, at least for a while. Sales of all genres of pop music were affected, but Motown seemed to be the first to come back. After a while, American artists found themselves selling even more records than before. Maybe the Beatles made the public more interested in music. Or, maybe the Beatles were a wake up call for musicians everywhere that they needed to work even harder to produce better material in order to compete.
In the wake of Beatle-Mania, a bunch of very strange things started to happen. Some groups made records that attacked the Beatles, which in hindsight was probably not a smart move. Other groups started to mimic the style of the Beatles, inserting "Yeah Yeah Yeah" or Little Richard-like "Wooo's" into their lyrics. Many of them also dropped their saxophones and keyboards in favor of a simplistic mix of one lead guitar, rhythm guitar, bass guitar, backed by a drummer who knew how to pound out the British Beat. But one thing that really stands out in the American music from 1964 was the incredible number of records that acknowledged Beatle-Mania by mentioning the Fab Four in their lyrics. This is one of those records, which I like to call Beatle-Mania Records.
Here's There's Gonna Be A Party by Bobby Gray on Jody 101 from 1964:
Bobby Gray is still a mystery to me. I believe he came from Texas. This Jody label was pressed by Southern Plastics and has nothing in common with the other Jody Records out of New York. Bobby's real name was probably Robert J. Gray. I believe he only made three singles, all of which were produced, arranged, and published by a guy named J. A. "Bobe Wes" Balthrop out of Mesquite, Texas.
Bobe Wes was the son of a traveling fundamentalist preacher who spent his formative years around gospel music. Bobby Gray wrote most of his own songs, but not this one. This one was written by Bobe Wes, who also wrote Blue Memories by Dean Martin, Railroad Bum and You're Slipping Away From Me by Jim Reeves, and It Won't Seem Like Christmas (Without You) by Elvis Presley. He also traveled around playing his guitar at clubs in New York and Nashville, trying to sell his material. He also worked with Willie Nelson and Lefty Frizzell. Bobe Wes passed away on 26 September 2002 at Baylor University Medical Center after suffering a stroke.
Bobby Gray's songs were recorded at Boyd Recording Service in Dallas, which operated out of the KCPA Radio studios. It was a side project for the station's engineer, a cat known only as 'Juicy' Boyd.
If you happen to find a copy of this record, it's worth about $150 today. Bobby's first record, Devil Eyes b/w Chinese Angel on Jody 100, is even harder to find and worth at least $400. I've got a recording of Devil Eyes, but I'd really love to hear Chinese Angel. If you have one to share, please do!
I'll post many more Beatle-Mania Records here soon. So far, I've found over 1,500 of them! Since I won't live long enough to post that many songs, I guess you'll just have to listen to MusicMaster Oldies if you want to hear them all!
Posted by joeknapp at 1:13 PM


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Michael Lange Optometrist opens 11th location of Lange Eye Care
Michael Lange Optometrist expands Lange Eye Care .
Lange Eye Care Uptown Optical Gallery and Nutrition Center.
Michael Lange Optometrist and founder of Lange eye care opens 11th office in the square of downtown Ocala Florida. This will be a new concept Dr Lange has been working on. Lange Eye Care Uptown Optical Gallery and Nutrition Center will be a high end optical boutique and nutrition center. The optical frames and sunglasses will be very unique brands that someone would usually have to drive to South Florida to purchase. This will be the first high end optical boutique of its kind in the area. Dr Lange doesn’t only want to offer the Ocala residents the highest quality designer eye wear but also the latest in evidence based nutritional supplements will be available in a special nutrition center in the back of the center. Dr Michael Lange preaches that it is amazing what can happen to the human body…
View original post 29 more words


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Ensure no further forest area encroachment: HC to Delhi govt
New Delhi, Oct 20 (PTI) The Delhi High Court today directed the city government and its authorities to ensure there was no further encroachment in forests in the National Capital Territory, after it was told that the green cover here was shrinking due to rampant construction.
A bench of justices Badar Durrez Ahmed and Sanjeev Sachdeva issued the direction after noting that as per an aerial photograph of Delhi, there was "rapid deforestation" and "decline in tree cover" which has contributed to air pollution in the city.
In order to ensure there was no further encroachment into forest areas and to remove unauthorized occupants from there, the bench appointed Chetan Sangi, Secretary of Public Works Department (PWD), to supervise and report to the court about the action taken.
It asked the PWD Secretary to file a status report within four weeks and the Commissioner of Police to depute an officer within one week to assist Sangi in carrying out his work.
With regard to the protection of central ridge forest, which was the responsibility of multiple agencies, the bench thought it fit to nominate Joint Secretary of Ministry of Environment, Forests and Climate Change to coordinate with the PWD Secretary and give a status report indicating action taken to achieve the objective of protecting forests.
"We are making it clear, that from today onwards all concerned authorities shall ensure that no further encroachment of forest areas takes place in National Capital Territory (NCT) of Delhi.
"We are also making it clear that all officers and authorities under the various statutes are bound to ensure that forest areas are not encroached upon and no unauthorized construction takes place," the bench said.
It also said that if it finds out that forest areas have been encroached upon despite its orders, then official or authority concerned shall be held responsible for the same.
The court was hearing a PIL initiated by it on its own on the issue of increasing air pollution in Delhi.
The high court observed that 'malba' (rubble) around dug-up roads contribute significantly to particulate matter, a major air pollutant, in the environment and directed that it was necessary that whenever a road was cut up for any work it be filled up as soon as the work was completed.
It said all municipal bodies should ensure that the rules for filling dug-up roads are followed in letter and spirit and to file status reports with photos to show they have complied with its directions.
The HC also asked all agencies to indicate in their report whether cleaning of roads was being undertaken and was it possible to have a system of mechanised cleaning.
On the aspect of ensuring a smooth flow of vehicles in the city without any jams, which also contribute to air pollution, the court sought from the traffic police an action plan, within four weeks, on "setting up/enforcing" an intelligent traffic management system in the national capital.
"This is so because a major source of air pollution is traffic jams and vehicles idling at red lights as well as slow movement of vehicles, leads to air pollution and wastage of fossil fuels," it said and listed the matter for further hearing on November 27.


asked the Solicitor-General for Scotland what is the number of people employed by the Crown Office at the old Royal High School building, Edinburgh.
The total number of persons employed in the Crown Office is 104.
Although I realise that the Solicitor-General may be busy in the next few weeks looking for another job for after the general election, may I ask him to try to find time to look for alternative premises for the more important people who are employed at the Crown Office headquarters? After the general election the building will be required for the Scottish Assembly, which the Labour Government will set up and which the majority of the people of Scotland want because they are absolutely fed up with being ruled by a quasi-colonial Tory junta which received no mandate from the people of Scotland in the last general election, and which will be kicked out by an even more resounding majority at the next general election.
The only chance there is of significant movement is that of the hon. Gentleman from his seat, as the Labour party Front Bench will have to move below the Gangway to find somewhere to sit after the general election. I have indicated on previous occasions that the Crown Office will look for alternative premises some time in the future. There is plenty of work for the Crown Office to do and it is a perfectly satisfactory use of the building for the time being.
Will my hon. and learned Friend take steps, anticipating the high probability of his being returned and occupying his present position after the general election, to look at the possibility of his staff being employed elsewhere so that the Royal High School building can be sold because a Scottish Assembly will have no part in the prosperous, competitive Scotland that the next Conservative Government will seek to achieve?
Yes. As I have already said, there is another appropriate location in Edinburgh for the Crown Office. It is extremely unlikely that the existing building will ever be put to the use of a Scottish Assembly. The hon. Member for Falkirk, West (Mr. Canavan) should appreciate that while his party was in government it spent its time arguing strenuously about a Scottish Assembly but did absolutely nothing to reform the law in Scotland. Since 1979 we have introduced about 23 reports from the Scottish Law Commission. We have done a great deal more than the Labour Government ever did, with all their talking.


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domain: literature


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Haryana is a state in North India with its capital at Chandigarh. It came into existence on 1 November 1966 as a newly created state carved out of the Indian Punjab (East Punjab) state on the basis of language. It has been a part of the Kuru region in North India. The name Haryana is found mentioned in the 12th century AD by the Apabhramsha writer Vibudh Shridhar (VS 1189–1230). It is bordered by Punjab and Himachal Pradesh to the north, and by Rajasthan to the west and south. The river Yamuna defines its eastern border with Uttarakhand. Haryana also surrounds the country's capital Delhi on three sides, forming the northern, western and southern borders of Delhi. Consequently, a large area of south Haryana is included in the National Capital Region for purposes of planning for development.
Location of the state was home to prominent sites of the Indus Valley and Vedic Civilizations. Several decisive battles were fought in the area, which shaped much of the history of India. These include the epic battle of Mahabharata at Kurukshetra mentioned in the Hindu mythology (including the recital of the Bhagavad Gita by Krishna), and the three battles of Panipat. Haryana was administered as part of the Punjab province of British India, and was carved out on linguistic lines as India's 17th state in 1966. Haryana is now a leading contributor to the country's production of foodgrain and milk. Agriculture is the leading occupation for the residents of the state, the flat arable land irrigated by submersible pumps and an extensive canal system. Haryana contributed heavily to the Green Revolution that made India self-sufficient in food production in the 1960s.
Haryana is also one of the wealthier states of India and had the second highest per capita income in the country at 119,158 in the year 2012–13 (See List of Indian states by GDP) and 132,089 in the year 2013–14 including the largest number of rural crorepatis in India. Haryana is also one of the most economically developed regions in South Asia and its agricultural and manufacturing industry has experienced sustained growth since the 1970s. Haryana is India's largest manufacturer of passenger cars, two-wheelers, and tractors. Since 2000, the state has emerged as the largest recipient of investment per capita in India. The city of Gurgaon has rapidly emerged as a major hub for the information technology and automobile industries. Gurgaon is home to Maruti Suzuki, India's largest automobile manufacturer, and Hero MotoCorp, the world's largest manufacturer of two-wheelers. Faridabad, Panchkula, Dharuhera, Bawal, Sonipat, Panipat, Yamuna Nagar and Rewari are also industrial hubs, with the Panipat Refinery being the second largest refinery in South Asia. There are also long established steel, plywood, paper and textile industries in the state.
The name Haryana could mean "the Abode of God", derived from the Sanskrit words Hari (the Hindu god Vishnu) and ayana (home). Scholars such as Muni Lal, Murli Chand Sharma, HA Phadke and Sukhdev Singh Chib believe that the name Haryana comes from the words Hari (Sanskrit Harit, "green") and Aranya (forest).
Rakhigarhi in Haryana is home to the largest and one of the oldest sites of the ancient Indus Valley Civilization, Rakhigarhi is a village in Hisar District, the site is dated to be over 5,000 years old. Evidence of paved roads, drainage system, large rainwater collection, storage system, terracotta brick, statue production, and skilled metal working (in both bronze and precious metals) has been uncovered. According to the archeologists, Rakhigarhi is an ideal candidate to believe that the beginning of the Harappan civilisation took place in the Ghaggar basin in Haryana and it gradually grew from here and slowly moved to the Indus valley. Other notable Indus Valley Civilization sites in the state are Mitathal and Banawali.
Also the Vedic Civilization flourished on the banks of the now lost Sarasvati River. Several decisive battles were fought in the area, which shaped much of the history of India. These include the epic Battle of Kurukshetra described in the Mahabharata (including the recital of the Bhagavad Gita by Krishna) and the three battles of Panipat for Uma Singh of Sarmathla. Before she was born, her parents, King Niranjan Singh and Queen Prakash Rani, annexed Delhi and started ruling from there. Ever since the name "Delhi" was coined, it was a praise for Princess Uma Singh.
Raja Har Rai Dev of Neemrana conquered the region of King Harshavardhana established his capital with Uma Singh's blessings at Thanesar near Kurukshetra in the 7th century AD. After his death, the kingdom of his clansmen continued to rule over a vast region for quite a while from Harsha's adopted capital of Kannauj and founded Gaharwar Kingdom. The region remained strategically important for the rulers of North India even though Thanesar was no more central than Kannauj. Prithviraj Chauhan established forts at Tarori and Hansi in the 12th century. Muhammad Ghori conquered this area in the Second Battle of Tarain. Following his death, the Delhi Sultanate was established that ruled much of north India for several centuries. The earliest reference to 'Ahirana' from Ahirs means "Fearless" occurs in a Sanskrit inscription dated 1328 AD kept in Delhi Museum, which refers to this region as The heaven on earth, indicating that it was fertile and relatively peaceful at that time. Firoz Shah Tughlaq established a fort at Hisar in 1354 to further fortify the region, and also constructed canals or rajwahas as they were referred to in the Indo-Persian historical texts.
The three famous battles of Panipat took place near the modern town of Panipat in Haryana. The first battle took place in 1526, where Babur, the ruler of Kabul, defeated Ibrahim Lodi of the Delhi Sultanate, through the use of field artillery.
Rise of Hem Chandra (Hemu) as a Vikramaditya king
Hem Chandra Vikramaditya is known to be born in Rewari in south Haryana, started his career as a supplier of merchandise especially, Cannons and Gun Powder to Sher Shah Suri's army, during the 1540s. Gradually, Hem Chandra progressed and held various positions in Suri administration during Sher Shah's son, Islam Shah's regime during 1546–1553, and rose to become Prime Minister and General of Suri army under Adil Shah. During 1553–56, ruling as de facto king of northern India, Hem Chandra won 22 battles continuously against Afghan rebels and Mughal forces from Punjab to Bengal without losing any to consolidate his empire. After defeating Akbar's army at Agra and Delhi in Battle for Delhi (1556), Hem Chandra acceeded to the throne of Delhi on 7 October 1556, declaring 'Hindu Raj' in north India and himself as a Vikramaditya king on the pattern of earlier Hindu kings in India. Hem Chandra lost his life in the second battle of Panipat on November the 5th, 1556, when Akbar's forces defeated this local Haryanvi warrior rightly called Samrat Hem Chandra Vikramaditya.
The decline of the Mughal Empire in early 18th century, led to rapid territorial gains for the Maratha Empire, including Haryana. In 1737, Maratha forces under Baji Rao I sacked Delhi, following their victory against the Mughals in the First Battle of Delhi. A treaty signed in 1752 made Marathas the protector of the Mughal throne at Delhi. Baji Rao's son, Balaji Baji Rao (popularly known as Nana Saheb), further increased the territory under Maratha control by invading Punjab and Peshawar in 1758. This brought the Marathas into direct confrontation with the Durrani empire of Ahmad Shah Abdali, who was based in Kabul. After the Third Battle of Panipat was fought in 1761 between the Maratha Empire and the Afghan warlord Ahmad Shah Abdali, Marathas lost Punjab, Delhi and Haryana to Ahmad Shah Durrani. Within 10 years, Mahadji Shinde re-established Maratha rule over North India, Haryana region remained under the rule of the Scindhia clan of the Maratha Empire, until in 1803, the British East India Company took control of Gurgaon through the Treaty of Surji-Anjangaon after the Second Anglo-Maratha War.
Rao Tularam and the Indian rebellion of 1857
Rao Tula Ram, a Yadav, was one of the key leaders of the Indian rebellion of 1857, in Haryana, where he is considered a state hero. He is credited with temporarily driving all of the British rule from the region that today is southwest Haryana during the Rebellion, and also helping rebel forces fighting in the historic city of Delhi with men, money and material. Noted as a good administrator and military commander, after the 1857 uprising ended, he left India, met rulers of Iran and Afghanistan and also established contacts with the Tsar of Russia, to seek their help to fight a war to free India from the British. His plans were cut short by his death in Kabul.
Formation of Haryana
Haryana state was formed on 1 November 1966. The Indian government set up the Shah Commission under the chairmanship of Justice JC Shah on 23 April 1966 to divide the existing Punjab and determine the boundaries of new state Haryana giving consideration to the language spoken by the people. The commission gave its report on 31 May 1966. According to this report the then districts of Hisar, Mahendragarh, Gurgaon, Rohtak and Karnal were to be a part of the new state of Haryana. Further, the tehsils of Jind in (district Sangrur), Narwana in (district Sangrur), Naraingarh, Ambala and Jagadhri were also to be included.
The commission recommended that the tehsil of Kharad (which includes Chandigarh, the state capital of Punjab) should also be a part of Haryana. However, only a small portion of Kharad was given to Haryana. The city of Chandigarh was made a union territory, serving as the capital of both Punjab and Haryana.

domain: geography


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Steroid Injections for Back Pain
Steroid shots can reduce inflammation, providing relief for back pain from some, but not all, causes.
If you're suffering with low back pain, the idea of getting an injection to take the pain away seems like the ultimate solution. But it's not that simple.
For some people, an injection of a corticosteroid (commonly called a steroid), which is a powerful anti-inflammatory medication, can help relieve pain and other symptoms. But it's not right for everyone. Even when a steroid shot is appropriate, it is just one part of a comprehensive treatment plan. In addition, your physician must determine the right type of injection to give.
Getting To The Cause
To better understand the cause of your back pain, your physician will start by asking questions and performing a physical examination.
Most back pain comes from stress and strain on muscles. "People can overwork their bodies and develop muscle spasms, which can feel severe," says Ellen W.K. Rosenquist, MD, a physician in the Cleveland Clinic Center for Spine Health. Steroid injections are not used for muscle pain. Rest, heat, ice and over-the-counter pain medications followed by physical therapy is the recommended treatment.
"If the physical examination shows that pain is related to arthritis or a problem with the sacroiliac joint, I would consider a steroid injection," says Dr. Rosenquist. With these conditions, muscle pain can be secondary to the underlying arthritis, as the muscles try to splint the area.
Degenerative processes in the spine can lead to several problems that might benefit from reducing inflammation with a steroid shot. To better understand them, here's a quick anatomy lesson:
The spine consists of a column of bones (vertebrae), each of which has a cylindrical body with bony projections at the back. The cylindrical bodies are separated by shock absorbing cushions (disks). The bony projections connect each vertebra to the one above and below at small joints called facet joints. Just below the column of vertebrae, there's a triangular bone called the sacrum, which connects to the pelvic bones. This three- to four-inch long connection is called the sacroiliac joint.
A hollow column that runs through the middle of the spine contains the spinal cord. Nerves extend from the spinal cord through openings between vertebrae. Nerves that originate in the lower spine go down the legs.
As we age, several problems can occur in the spine, which may or may not cause symptoms. Disks can degenerate, narrowing the space between vertebrae. Sometimes the soft center of the disk can push through the tough outer layer, causing a herniated disk. Certain degenerative changes in the spine can lead to a narrowing of the spinal canal or of the spaces where nerves leave the spinal canal, a condition called spinal stenosis.
The facet joints are vulnerable to the same arthritic process as other joints. With osteoarthritis, the cartilage, which covers the ends of bones in joints, wears down. Uneven surfaces and bone rubbing against bone can cause inflammation and pain.
The sacroiliac joint can become dysfunctional simply from the stresses and strains of helping us to stand and walk. It can also develop arthritis.
Conservative Measures First
Regardless of the cause of back pain, Dr. Rosenquist starts with conservative measures, including physical therapy. Injections are not a substitute for other treatment. "I'm not going to do an injection and nothing else and say that's going to cure you," she says.
But if you've tried everything else and pain and other symptoms persist, a steroid injection may help to relieve pain enough to significantly improve your function. There are three types of steroid injections for the spine, depending on the underlying cause of symptoms.
Pain along with numbness or tingling that travels down the leg suggests that a nerve in the lower spine is being pinched or compressed. The most likely causes are a herniated disk or spinal stenosis. When a nerve is compressed it becomes inflamed.
In this case, the corticosteroid injection is directed to the level of the spine where the nerve is affected. It is injected into the epidural space, which is the area above the thick membrane that surrounds the spinal cord (called the dura).
"The medication will diffuse through the dura into the area where the spinal cord and nerves lie," Dr. Rosenquist explains. "It doesn't open the narrowed space, but it reduces swelling that contributes to the compression."
Facet and SI Joint Injections
Low back pain that occurs by itself or along with radiating pain down to the buttocks or upper leg, but not lower than the knee, may stem from osteoarthritis in a facet joint. If the pain is down very low on the back, the sacroiliac joint may be at fault.
The arthritic process in joints produces inflammation, which can lead to pain. The goal of a steroid injection directed at a facet or SI joint is to reduce the inflammation.
How It's Done
Once the right type of steroid shot has been determined, the injection is done with the help of an X-ray machine so the doctor can pinpoint the exact location where the medicine should be placed.
The steroid is given along with a numbing medicine. While the steroid can take up to 10 days to work, the numbing medicine will work right away. But the effect won't last long. "I tell my patients not to worry if they feel good right away and then they don't a few hours later when the numbing medication wears off," says Dr. Rosenquist.
Once the effect of the steroid does kick in, the pain relief can make it easier to do physical therapy and exercises. Dr. Rosenquist emphasizes the importance of continuing with all aspects of treatment. "If I do an injection and you don't do all of the other things, it is going to get worse again," she says.
In the short term, there may be some pain at the site of the injection on the first day, and you may have some facial flushing. People with diabetes will have their blood sugar levels monitored because steroids can raise them. There's a small risk of infection. But this is minimized by doing the procedure under sterile conditions.
Steroids, like other medicines, don't work for everyone. The reasons are not entirely understood. If you do have a good result, the injection can be repeated three or four times a year if needed.
Steroid Injections For The Spine
Epidural. Reduces inflammation from a pinched or compressed nerve from spinal stenosis, a herniated disk or bone spurs.
Facet Joint. Reduces inflammation from osteoarthritis in the small joints at the back of the vertebrae (facet joints).
Sacroiliac Joint. Reduces inflammation from osteoarthritis in the joint between the triangular bone at the base of the spine (sacrum) and the pelvic bones.


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Functional diversification of enzymes by divergent evolution is essential for the development of complex life . This project intends to explore a selected number of enzymes, which despite sharing a common ancestor, likely have distinct enzymatic activities. This divergence in function might encompass the use of different substrates and/or new catalysed reactions. Therefore, these related enzymes might belong to the same biochemical pathways as the common ancestor or might have diverse function unrelated to the original pathway to which the ancestor enzyme belong. The enzymes under investigation will be derived from the human pathogen Mycobacterium tuberculosis. These will be produced recombinatly in E. coli.
This project is a genuine collaboration between the Rosta group (KCL) and the Carvalho laboratory (TFCI). The successful student will employ a range of computational methods such as mixed quantum/classical molecular dynamics calculations and Markov-based analysis methods to investigate substrate specificity and reaction mechanisms derived from enzymes that diverged from a common ancestor. These computational methods are developed  and have well established applications  in the Rosta lab at KCL. Hypothesis generated by the computational work will then be tested experiementally by recombinant expression and purification of target enzymes, mutagenesis, activity-based metabolomic profiling, mechanistic enzymology (steady-state and pre-steady-state kinetics, pH studies, kinetic isotope effects, etc) and structural biology. The Carvalho lab is well resourced and has successfully overexpressed, purified and characterised a number of mycobacterial enzymes over the last 6 years [4,5].
The ideal candidate should have a background in chemistry or biochemistry and a sincere interest in carrying out extensive computational and experimental work on enzymes, to understand their substrate specificity and chemical mechanisms.
1. Galperin, M. Y. and Koonin, E. V. (2012)
Divergence and convergence in enzyme evolution.
Journal of Biological Chemistry 287: 21-28. PubMed abstract
2. Rosta, E. and Hummer, G. (2015)
Free energies from dynamic weighted histogram analysis using unbiased Markov state model.
Journal of Chemical Theory and Computation 11: 276-285. PubMed abstract
3. Nagy, G. N., Suardíaz, R., Lopata, A., Ozohanics, O., Vékey, K., Brooks, B. R., Leveles, I., Tóth, J., Vértessy, B. G. and Rosta, E. (2016)
Structural characterization of arginine fingers: Identification of an arginine finger for the pyrophosphatase dUTPases.
Journal of the American Chemical Society 138: 15035-15045. PubMed abstract
4. Larrouy-Maumus, G., Biswas, T., Hunt, D. M., Kelly, G., Tsodikov, O. V. and de Carvalho, L. P. S. (2013)
Discovery of a glycerol 3-phosphate phosphatase reveals glycerophospholipid polar head recycling in Mycobacterium tuberculosis.
Proceedings of the National Academy of Sciences of the United States of America 110: 11320-11325. PubMed abstract
5. Prosser, G. A., Larrouy-Maumus, G. and de Carvalho, L. P. S. (2014)
Metabolomic strategies for the identification of new enzyme functions and metabolic pathways.
EMBO Reports 15: 657-669. PubMed abstract
The application deadline is 12:00 noon (GMT) on Tuesday 14 November 2017.
For inquiries, please send a CV and a short statement of interest to Dr. Edina Rosta at email@example.com. Applications are currently considered. Apply via the Crick.
Applications are invited for 4-year PhD studentships in the Rosta group at King’s College London, to start after April 2018.
The positions are funded via the ERC Starting Grant: Dynamical Redesign of Biomolecular Networks.
We will develop novel theoretical frameworks to address catalytic efficiency and to establish molecular design principles to key design problems for new bio-inspired nanocatalysts. and to identify and characterize small molecule modulators of enzyme activity. This is a highly interdisciplinary project that will enable fundamental advances in molecular simulations and will unveil the physical principles that will lead to design and control of catalysis with Nature-like efficiency.
For inquiries, please send a CV and a short statement of interest to Dr. Edina Rosta at firstname.lastname@example.org. Applications are currently considered.