text:
For long term storage, we suggest that betulin be stored as supplied at -20°C. It ...
A stock solution may be made by dissolving the betulin in the solvent of choice.
Product Information Betulin
Item No. 11041 CAS Registry No.: 473-98-3 Formal Name: lup-20(29)-ene-3β,28-diol Synonyms: NSC 4644, Trochol MF: C30H50O2 FW: 442.7 Purity: ≥98% Stability: ≥2 years at -20°C Supplied as: A crystalline solid
CH2 H3C H H CH3
Laboratory Procedures For long term storage, we suggest that betulin be stored as supplied at -20°C. It should be stable for at least two years. Betulin is supplied as a crystalline solid. A stock solution may be made by dissolving the betulin in the solvent of choice. Betulin is soluble in dimethyl formamide (DMF), which should be purged with an inert gas. The solubility of betulin in DMF is approximately 2.5 mg/ml. Betulin is sparingly soluble in aqueous solutions. To enhance aqueous solubility, dilute the organic solvent solution into aqueous buffers or isotonic saline. If performing biological experiments, ensure the residual amount of organic solvent is insignificant, since organic solvents may have physiological effects at low concentrations. We do not recommend storing the aqueous solution for more than one day. Sterol regulatory element binding protein 2 (SREBP-2) regulates cholesterol synthesis by activating the transcription of genes for HMG-CoA reductase and other enzymes of the cholesterol synthetic pathway.1,2 When cellular sterol levels are high, SREBP is bound by SCAP and Insig to ER membranes as a glycosylated precursor protein. Upon cholesterol depletion, the protein is cleaved to its active form and translocated into the nucleus to stimulate transcription of genes involved in the uptake and synthesis of cholesterol.3 Betulin, the precursor of betulinic acid, is a pentacyclic triterpene found in the bark of birch trees. Betulin inhibits the SREBP-driven pathway of cholesterol and fatty acid biosynthesis by promoting SCAP–Insig binding which prevents the activation and release of SREBP-2 from the ER.4 At 15-30 mg/kg/day, betulin has been shown to decrease lipid levels and increase insulin sensitivity in mice fed a westerntype diet.4 In an atherosclerosis disease model, 30 mg/kg/day betulin can reduce the size and improve the stability of atherosclerotic plaques in LDLR-knockout mice.4 At 2.5-5 μg/ml betulin, in combination with cholesterol, demonstrates anticancer effects by inducing apoptosis in Jurkat cells, A549 lung carcinoma cells, and HeLa cervical carcinoma cells.5 References 1. Sakai, J., Nohturfft, A., Goldstein, J.L., et al. Cleavage of sterol regulatory element-binding proteins (SREBPs) at site-1 requires interaction with SREBP cleavage-activating protein. Evidence from in vivo competition studies. J. Biol. Chem. 273(10), 5785-5793 (1998). 2. Brown, M.S. and Goldstein, J.L. The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. Cell 89, 331-340 (1997). 3. Smith, L.H., Petrie, M.S., Morrow, J.D., et al. The sterol response element binding protein regulates cyclooxygenase-2 gene expression in endothelial cells. J. Lipid Res. 46, 862-871 (2005). 4. Tang, J.-J., Li, J.-G., Qi, W., et al. Inhibition of SREBP by a small molecule, betulin, improves hyperlipidemia and insulin resistance and reduces atherosclerotic plaques. Cell Metab. 13(1), 44-56 (2011). 5. Mullauer, F.B., Kessler, J.H., and Medema, J.P. Betulin is a potent anti-tumor agent that is enhanced by cholesterol. PLoS One 4(4), (2009). Related Products For a list of related products please visit: www.caymanchem.com/catalog/11041
WARNING: This product is for laboratory research only: not for administration to humans. Not for human or veterinary diagnostic or therapeutic use.
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MATERIAL SAFETY DATA This material should be considered hazardous until information to the contrary becomes available. Do not ingest, swallow, or inhale. Do not get in eyes, on skin, or on clothing. Wash thoroughly after handling. This information contains some, but not all, of the information required for the safe and proper use of this material. Before use, the user must review the complete Material Safety Data Sheet, which has been sent via email to your institution.
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WARRANTY AND LIMITATION OF REMEDY Cayman Chemical Company makes no warranty or guarantee of any kind, whether written or oral, expressed or implied, including without limitation, any warranty of fitness for a particular purpose, suitability and merchantability, which extends beyond the description of the chemicals hereof. Cayman warrants only to the original customer that the material will meet our specifications at the time of delivery. Cayman will carry out its delivery obligations with due care and skill. Thus, in no event will Cayman have any obligation or liability, whether in tort (including negligence) or in contract, for any direct, indirect, incidental or consequential damages, even if Cayman is informed about their possible existence. This limitation of liability does not apply in the case of intentional acts or negligence of Cayman, its directors or its employees. Buyer’s exclusive remedy and Cayman’s sole liability hereunder shall be limited to a refund of the purchase price, or at Cayman’s option, the replacement, at no cost to Buyer, of all material that does not meet our specifications. Said refund or replacement is conditioned on Buyer giving written notice to Cayman within thirty (30) days after arrival of the material at its destination. Failure of Buyer to give said notice within thirty (30) days shall constitute a waiver by Buyer of all claims hereunder with respect to said material. For further details, please refer to our Warranty and Limitation of Remedy located on our website and in our catalog. Copyright Cayman Chemical Company, 07/17/2013
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domain: biology


text:
411's POUND-FOR-POUND RANKINGS Ronda Rousey, Chris Weidman and T.J. Dillashaw all retained their UFC championships while Rafael dos Anjors stopped Benson Henderson! See what effect those had on the latest pound-for-pound 411 MMA Rankings!
TOP 8 GAMER STEREOTYPES From Halo-loving frat guys and Angry Bird-playing casual games to obsessive MMO players, misogynists and social justice warriors and more, 411's Marc Morrison looks at the top 8 gamer stereotypes!
(09.01.2014) - Tony Acero John Cena interrupted the Highlight Reel, Cesaro and the Miz battled Sheamus and Dolph Ziggler, Mark Henry made a stand against Rusev, The Bellas got involved with the Divas Title and more! Check out 411's full WWE Raw report for all the details!
(09.01.2014) - Sean Garmer Sean Garmer, Robert Cooper, and Daniel Anderson discuss Microsoft's standalone Kinect, PSN getting hacked again, Nintendo going hardcore, and all the rest of the news that's happened the past two weeks in gaming.

domain: entertainment


The incredible life of Soul music icon Bobby Womack and great new music from Tiger Bomb and 50 FT. Furies
Manage episode 274527379 series 2807103
On this episode of Blowing Smoke with Twisted Rico, we hear a few early chapters from Steev's unreleased book entitled "Independent Record Scum", Delve into the remarkable rise, fall, and rise again of soul legend Bobby Womack, and hear incredible new songs from Portland Maine's Tiger Bomb and Jersey City's 50 Ft. Furies.
Music featured in this Episode
The Charms "So Pretty"
Tiger Bomb "Come On Baby"
50 Ft. Furies "Charlottesville"
Recorded at New Alliance, Somerville MA by Herb Morsiglio


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Slow Cooker Beef Stroganoff
Getting started Equipment you will need: Slow cooker , mixing spoon, strainer, large pot, colander, spoon Set slow cooker to low setting Do right away when you get home: Action steps 1 & 2
2 lb. cubed steak
2 cans cream of mushroom soup
1 (12 oz.) jar beef gravy
½ packet of Lipton onion soup mix
1 (16 oz.) box of egg noodles
1. Place steak in slow cooker.
2. Pour ingredients on top of cubed steak. Sprinkle ½ soup mix on top of soup and gravy. Cook on low for 3 hours, stirring occasionally.
3. Fill pot ¾ full of water, boil egg noodles until al dente, and strain using colander. Serve beef mixture over noodles.
Suggested Side Items: mixed greens and a glass of milk
Tips: To decrease the sodium content of this recipe, choose lower sodium versions of the cream of mushroom soups, gravy, and soup mix. Try adding fresh mushrooms to this recipe.
Shopping list: Cubed steak 1 packet Lipton onion soup mix Cream of mushroom soup (2 cans) Beef gravy (12 oz. can)
Check for: Egg noodles
Mixed greens for side salad
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domain: food


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After seeing thousands of patients now for years and from personal experience, I still believe it comes down to staying away from processed foods and cooking at home whenever possible. Eating a variety of fresh fruits, vegetables, proteins, and fiber. Also, cutting out any sugary liquid calories; staying away from sodas, juices and the infamous sweet tea! Keeping stress levels under control and incorporating exercise into your routine will also be key to breaking through challenging times when you are having trouble with continued weight loss.
The researchers agree that the diet itself isn’t inherently dangerous. But, cautions Weiss, “If you have any medical condition, if you take any medicine at all – there are lots of things that change how medicines work in our bodies, and nutrition is definitely one of them. If you’re making a real change in your nutrition, you really should talk to your doctor.”
After increasing water intake and replacing electrolytes, it should relieve most all symptoms of Keto Flu. For an average person that is starting a ketogenic diet, eating 20-30g of net carbs a day, the entire adaptation process will take about 4-5 days. My advice is to cut your carbs to fewer than 15g to ensure that you are well on your way into ketosis within one week. If you are experiencing any more keto flu symptoms, double check your electrolyte intake and adjust.
U.S. News’s Best Diets rankings are put together by a panel of nutritionists, dietary consultants, and doctors specializing in diabetes, heart health, and weight loss. Each member of the panel scored all 41 diets in seven different areas, including how easy they are to follow, how well they protect against chronic disease, and how likely it is that followers will actually lose weight and keep it off.
Another difference between older and newer studies is that the type of patients treated with the ketogenic diet has changed over time. When first developed and used, the ketogenic diet was not a treatment of last resort; in contrast, the children in modern studies have already tried and failed a number of anticonvulsant drugs, so may be assumed to have more difficult-to-treat epilepsy. Early and modern studies also differ because the treatment protocol has changed. In older protocols, the diet was initiated with a prolonged fast, designed to lose 5–10% body weight, and heavily restricted the calorie intake. Concerns over child health and growth led to a relaxation of the diet's restrictions. Fluid restriction was once a feature of the diet, but this led to increased risk of constipation and kidney stones, and is no longer considered beneficial.
"The eating plan focuses on reducing sodium intake and eating more fruits and vegetables," says Amy Gorin, MS, RDN, owner of Amy Gorin Nutrition in the New York City area. "It also emphasizes eating whole foods — such as fruits, vegetables, whole grains, fish, poultry, beans, nuts, and vegetable oils — and limits foods high in saturated fat. That includes fatty meats, full-fat dairy, and tropical oils like palm kernel oil, palm oil, and coconut oil. It also limits sugar-sweetened beverages and foods."
It is important to understand that the statement that carbohydrates are “nonessential” is not only factually inaccurate, it results in adopting a low-carbohydrate diet or ketogenic diet that increases your risk for a wide variety of chronic health conditions that may ultimately shorten lifespan, decrease your quality of life, and accelerate your risk for chronic disease.
In addition, on the day the diet was initiated, diabetes medications were reduced – generally, insulin doses were halved, and sulfonylurea doses were halved or discontinued. Due to the possible diuretic effects of the diet soon after initiation, diuretic medications were discontinued if of low dosage (up to 25 mg of hydrochlorothiazide or 20 mg of furosemide) or halved if of higher dosage. Participants were also instructed to take a standard multivitamin and drink 6–8 glasses of water daily, and were encouraged to exercise aerobically for 30 minutes at least three times per week.
WY conceived, designed, and coordinated the study; participated in data collection; performed statistical analysis; and drafted the manuscript. MF assisted with study design, performed data collection, and helped to draft the manuscript. AC analyzed the food records. MV assisted with study/intervention design and safety monitoring. EW participated in the conception and design of the study, and assisted with the statistical analysis. All authors read and approved the final manuscript.
Have Protein at Every Meal and Snack. Adding a source of lean or low-fat protein to each meal and snack will help keep you feeling full longer so you're less likely to overeat. Try low-fat yogurt, small portion of nuts, peanut butter, eggs, beans, or lean meats. Experts also recommend eating small, frequent meals and snacks (every 3-4 hours), to keep your blood sugar levels steady and to avoid overindulging.
The ketogenic diet reduces seizure frequency by more than 50% in half of the patients who try it and by more than 90% in a third of patients. Three-quarters of children who respond do so within two weeks, though experts recommend a trial of at least three months before assuming it has been ineffective. Children with refractory epilepsy are more likely to benefit from the ketogenic diet than from trying another anticonvulsant drug. There is some evidence that adolescents and adults may also benefit from the diet.
Also, if you listen to Dr Bernstein talk about his childhood (he is well into his 80’s), the “original” recommended diet was only ketogenic in the sense that it was high-carb and caused keto-acidosis, which he describes as almost killing him as a teenager. He still considers the ADA recommendations as ketogenic for this reason (you only have to listen to him a short time to hear him railing against the ADA).
2. A strong, healthy heart. Eating Mediterranean decreases practically every heart-disease risk factor -- high blood pressure, cholesterol, and triglyceride levels. When 605 patients who'd had a first heart attack followed the diet for four years, they had a 50 to 70 percent lower risk of having a second heart attack, angina, or a stroke or pulmonary embolism. "There's no single aspect of the diet that keeps your heart healthy," says Dr. Stampfer; it's the synergy of all the diet's elements. Antioxidants in fruits, vegetables, and beans help prevent the atherosclerosis that can make plaque build up in arteries. Omega-3 fatty acids in fish lower blood pressure, arrhythmia risk, and triglyceride levels. Olive oil lessens LDL ("bad") cholesterol. And wine and other spirits in moderation may lower heart-disease risk.
Financial disclosures: There were no conflicts of interest reported except for Dr Bernstein who has received royalties for books on the management of diabetes (which were used by members of the online social media group surveyed in this study). Dr. Hallberg who holds stock options and receives research support from Virta Health, and consulting fees from Atkins. Dr. Rhodes is the site principal investigator in clinical trials for pediatric type 2 diabetes that are sponsored by Merck and AstraZeneca. Dr. Westman has an ownership interest in companies using low-carbohydrate principles, and he receives royalties for books related to low-carbohydrate diets. Dr. Ludwig has received royalties from books on nutrition and obesity; and Dr. Galati is author of Eating Yourself Sick: How to stop obesity, fatty liver, and diabetes from killing you and your family (2018).
Congratulations to you!! Keep up the good work. And, I have to say again, choosing the keto way of life as a type one diabetic is a lot easier than one would think, right?!. It is so rewarding, as you point out, and actually quite easy (lose the carb cravings and enjoy eating everything that you can!). I honestly feel more FREEDOM eating this way than I did eating the other way for 20 years and I love the normal sugars and better energy. Also the decrease in inflammation is awesome.
However, the meta-analysis was riddled with confounding variables — one of which being their lackadaisical definition of a low-carb diet. The researchers identified a low-carb diet as a diet where less than 45% of its calories come from carbs. With such a lax criterion for low-carb, it is difficult to tell if a true low-carb diet (i.e., fewer than 26% of calories coming from carbs) is genuinely the best dietary option for type 2 diabetics.
There isn't "a" Mediterranean diet. Greeks eat differently from Italians, who eat differently from the French and Spanish. But they share many of the same principles. Working with the Harvard School of Public Health, Oldways, a nonprofit food think tank in Boston, developed a consumer-friendly Mediterranean diet pyramid that offers guidelines on how to fill your plate – and maybe wineglass – the Mediterranean way.
Two additional shortcuts that can easily be worked into a DASH diet plan are meal prepping and batch cooking—both of which are important for quick, healthy eating. Meal prepping doesn’t have to mean cooking a full meal, either. It’s just preparing components that can be used to toss together a quick meal—like baking chicken breasts, roasting vegetables, and cooking a whole grain like quinoa. You can also minimize time spent in the kitchen by buying weekly salad greens, bags of pre-cut veggies, and prepping produce at the start of the week.
We recently published an article documenting the grim long-term effects of low-carbohydrate diets, in which we explain the evidence-based research showing that low-carbohydrate diets high in fat and protein including meat, dairy products, eggs, fish, and oil actually worsen diabetes health, increase cancer risk, increase cholesterol, increase atherosclerosis, harden blood vessels, and increase all-cause mortality.
Now I have to say, I am not a supporter of rigid plans, however it is important to eat at somewhat regular times so you don’t end up feeling very-very hungry at any particularly moment of the day. Having said that, I also think it is important to be able to actually feel hunger, and look forward to eating a meal. While adding a snack here and there is good to keep blood sugar and hunger levels in balance, snacking can also backfire. Many times we eat a snack without being hungry or we depend on ready-made snacks such as granola bars, juices, smoothies etc. which not only add quite a few calories but also are a processed food with all that entails.
There are many ways in which epilepsy occurs. Examples of pathological physiology include: unusual excitatory connections within the neuronal network of the brain; abnormal neuron structure leading to altered current flow; decreased inhibitory neurotransmitter synthesis; ineffective receptors for inhibitory neurotransmitters; insufficient breakdown of excitatory neurotransmitters leading to excess; immature synapse development; and impaired function of ionic channels.
The scale is not necessarily your friend. You may want to lose fat – but the scale measures muscles, bone and internal organs as well. Gaining muscle is a good thing. Thus weight or BMI are imperfect ways to measure your progress. This is especially true if you’re just coming off a long period of semi-starvation (calorie counting), as your body may want to restore lost muscles etc. Starting weight training and gaining muscle can also hide your fat loss.
The good news here is no! All the evidence points to the fact that a low carbohydrate diet actually does lower blood glucose and A1c levels and does contribute to weight loss. The problem is we do not yet have enough large studies, over enough sustained years to support evidence that people with diabetes can remain on a highly restrictive Ketogenic Diet for the rest of their life and also not have other consequences to their health.
Take the word DIET out of this book because it has to be a lifestyle change. Either you want to lose weight, or this will be just another part of yo-yoing. Either you want to get your blood pressure down, or you'll accept you doctor's order to start a second antihypertensive. I just came off 6 months of veganism, so the beef eating especially revolted me at first, but this is healthy eating at it's finest. Low-carb, lots of veggies and eventually fruits - even alcohol (either as a grain - beer, ...more
Yes, they're technically a fruit, but we think olives deserve a shout-out all of their own, since they're also a great source of healthy fats and are one of a few keto-approved packaged foods. Plus, they're a great source of antioxidants, will satisfy your craving for something salty, and are blissfully low-carb. “About a palm's worth only has 3 grams of net carbs,” Sarah Jadin, RD, told Health in a previous interview.
The only limitations: processed foods, and excess intake of fats, sugars, and sodium. And, yes, nixing processed foods pretty much takes care of the fat, sugar, and sodium problem, Srinath says. Research published in BMJ Journal shows that ultra-processed foods make up 58 percent of all of the calories and 90 percent of the added sugars that the average American consumes in a given day. And 75 percent of the average American’s sodium consumption (which is about 1.5 times the RDA of sodium per day, according to the Centers for Disease Control and Prevention) comes from processed foods, per Harvard University.
The herbs and spices associated with the Mediterranean diet shine at dinner. Meal options include fish like grilled salmon or pan-seared trout, seasoned with lemon and dill; chicken baked with a little olive oil and rosemary; grilled lamb chops with mint; mussels cooked in a tomato, garlic and wine broth; chili made with ground turkey, kidney beans and cayenne, or vegetarian-style with a mix of beans; and scallops sauteed with mushrooms and leeks. Have a 4-ounce serving of protein, and fill the rest of your plate with cooked veggies, like cauliflower, broccoli, brussels sprouts, or green beans.
If you've been trying to eat healthy for a long time, you know how quickly you get sick of chicken breasts and broccoli. Break out of your diet rut with the Middle Eastern diet. It's based on the same principles as the Mediterranean diet but with more of an emphasis on plant-based foods and a different flavor profile. With all the tasty and healthy spices, you'll never get bored of making dinner and you'll get all the same heart-healthy benefits as its geographical cousin's diet.
Some people on a keto or low carb diet choose to count total carbs instead of net carbs. This makes it more difficult to fit in more leafy greens and low carb vegetables (which are filled with fiber), so you should only try that if you don’t get results with a net carb method. And, start with reducing sugar alcohols and low carb treats before deciding to do a “total carbs” method.
Choice #1: Lathero Dish (seasonal vegetables or beans cooked with olive oil, herbs, and tomato sauce accompanied by bread and cheese). This is what you will have 3-4 times a week. Typically this is green beans, peas, spanakorizo (spinach-rice) and cauliflower cooked in this way. This is accompanied by a slice of bread and feta. Click for lathera recipes. Please note that one serving consists of 3-4 servings of vegetables.
What the doctors never tell you is that you could also just eat completely different and take none of this crap. So that’s what I did. I stopped all of them all at once. Sure I don’t recommend that, but this damn disease and my disgusting visceral fat filled stomach ruined every aspect of my life-professional, relationships, sexual, mental. I am now 41 living back at home having to start from the bottom. I don’t want what the book recommends. I want every disgusting piece of fat off this body so I can excel again. If staying in ketosis every moment for the rest of my life will get me there then that’s what I’m going to do.
The ketogenic diet is usually initiated in combination with the patient's existing anticonvulsant regimen, though patients may be weaned off anticonvulsants if the diet is successful. There is some evidence of synergistic benefits when the diet is combined with the vagus nerve stimulator or with the drug zonisamide, and that the diet may be less successful in children receiving phenobarbital.
In 2008, researchers conducted a 24-week study to determine the effects of a low-carbohydrate diet on people with type 2 diabetes and obesity. At the end of the study, participants who followed the ketogenic diet saw greater improvements in glycemic control and medication reduction compared to those who followed a low-glycemic diet. A study from 2017 found the ketogenic diet outperformed a conventional, low-fat diabetes diet over 32 weeks in regards to weight loss and A1c. A 2013 review reports again that a ketogenic diet can lead to more significant improvements in blood sugar control, A1c, weight loss, and discontinued insulin requirements than other diets.
With the keto diet, your body converts fat, instead of sugar, into energy. The diet was created in 1924 as a treatment for epilepsy, but the effects of this eating pattern are also being studied for type 2 diabetes. The ketogenic diet may improve blood glucose (sugar) levels while also reducing the need for insulin. However, the diet does come with risks, so make sure to discuss it with your doctor before making drastic dietary changes.
I don't think this is the same as the DASH diet that was developed by the National Heart Lung and Blood Institute. That diet is more common sense than this Atkins rip off. The DASH diet was developed to prevent high blood pressure. It consists of eating more fruits, veggies, and whole grains and avoiding excess salt. This book is not that diet. I hate diets that eliminate foods even if only for two weeks.
Is Keto Worth It? Know The Health Benefits And Risks Before Going On A Keto DietThe ketogenic diet helps to bring your body into a metabolic state which is known as the ketosis. Ketosis occurs when the body has run out of its glycogen (which is basically sugar) stores so it needs to find another source of fuel. By: DoctorNDTV Updated: Dec 8, 2018 10:12 IST 4-Min Read SHARES The primary goal of the ketogenic diet is weight loss.
On the ketogenic diet, carbohydrates are restricted and so cannot provide for all the metabolic needs of the body. Instead, fatty acids are used as the major source of fuel. These are used through fatty-acid oxidation in the cell's mitochondria (the energy-producing parts of the cell). Humans can convert some amino acids into glucose by a process called gluconeogenesis, but cannot do this by using fatty acids. Since amino acids are needed to make proteins, which are essential for growth and repair of body tissues, these cannot be used only to produce glucose. This could pose a problem for the brain, since it is normally fuelled solely by glucose, and most fatty acids do not cross the blood–brain barrier. However, the liver can use long-chain fatty acids to synthesise the three ketone bodies β-hydroxybutyrate, acetoacetate and acetone. These ketone bodies enter the brain and partially substitute for blood glucose as a source of energy.
What the diet advocate says: The food baby of the US reality couple Heather and Terry Dubrow (she stars in the Real Housewives of Orange County; he’s a plastic surgeon starring in a show called Botched). ‘As opposed to the keto diet that aims to get you to a ketogenic state of using fat as fuel, which isn’t healthy or sustainable in my opinion, interval eating helps you go into a fat-burning state that leads to increased energy and cell renewal - a process called autophagy, the toxin-eating phase,’ says Terry.
For patients who benefit, half achieve a seizure reduction within five days (if the diet starts with an initial fast of one to two days), three-quarters achieve a reduction within two weeks, and 90% achieve a reduction within 23 days. If the diet does not begin with a fast, the time for half of the patients to achieve an improvement is longer (two weeks) but the long-term seizure reduction rates are unaffected. Parents are encouraged to persist with the diet for at least three months before any final consideration is made regarding efficacy.
Hi Gigi, Low carb and keto is about the balance of macronutrients eaten (fat, protein and carbs), not specifically meat or lack thereof. Most people on keto do eat meat, though some people do vegetarian keto. Fat is actually necessary for many body processes. There is no issue for the kidneys with a high fat diet, but if you eat too much protein that isn’t great for the kidneys. It’s a common misconception that keto is high protein (it isn’t). Keto is great for diabetics as it naturally helps stabilize insulin. All of this being said, please know I’m not a doctor and you should consult your doctor on any medical questions or before starting any diet. If you have more questions that aren’t medical questions, I recommend our low carb & keto support group here.
If you like eating meat and want to lose weight, you might be tempted to try this recent extreme diet fad that proponents have made some pretty outrageous claims about. One: that eating nothing but meat can cure you of autoimmune diseases. The problem is that there’s no good research to support that notion, or any other health claim, for that matter. Indeed, omitting foods known to be good for you — fruits and veggies among them — can lead to a bunch of unwanted side effects, including constipation and potentially dangerous nutrient deficiencies. Still, since you’re cutting out so many food groups, there’s a decent chance you’ll lose weight, experts say. Regardless of any possible benefits you might see, this restrictive approach is definitely one you’ll want to ask your doc about before you even consider diving in.
There are many physiological reasons for eating enough carbohydrates throughout the waking hours to maintain a steady blood glucose level…a couple of important reasons are to minimize the hepatic release of glucose (from the liver) and to help prevent hypoglycemia which can be very dangerous and lead to hypoglycemic unawareness over a short period of time. Each person is different of course..if you aren’t taking insulin, or pills that lower your blood glucose levels, you may not have to worry about low blood sugars. The reality is, most people with diabetes do; it can be very dangerous for some to not get enough carbohydrates at each meal.
The ADA has recommended since 2013 we use our best clinical judgement in recommending a low carbohydrate diet for people with diabetes, recognizing it needs to be individualized. 60-75 grams is the carbohydrate amount I would give to a very tall, large boned man or perhaps an active teen or young adult. I would never recommend that many carbohydrates for an average size man who was trying to lose weight; he would get 45-60 grams of carbohydrates per meal and 15-30 grams for snacks. A women trying to lose weight would get 30-45 grams of carbohydrates per meal and 15 grams for snacks.
More good news: Snacks are totally allowed (and I'm not just talking about carrot sticks). There are plenty of packaged options out there designed for keto fans. FATBAR is one of them. These snack bars have 200 calories, 16 grams of fat, and four grams of net carbs. They're also plant-based and are made with almond or cashew butter, cocoa butter, coconut, pea protein, sunflower seeds, and chia seeds.
Luckily today, we do not have to treat any type of diabetes with this barbaric method. There are so many healthy food options for most people today in modern society. In America, most of us are blessed to have access to healthy food options. I did see the research that Dr. Westman has completed at Duke University and did reference one of his articles above (reference #7 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1325029/). I have no doubt the diet works, I’ve done it and lost weight really fast, so I know from firsthand experience that it works. You will lose weight which will have wonderful effects on every aspect of your health. The problem I have is, can anyone go the rest of their life without consuming anything white EVER? Do you think every author of all those books actually does that? I would offer to put them all on a lie detector to prove that they haven’t lived 40 years without consuming one white thing or one fruit or anything with sugar in it. My question is, what quality of life do they really have if they have? I for one will NOT be giving up my or my family’s birthday cake!
It sounds as if you may have been following a very strict keto protocol. I’m not, and have not followed a ketogenic diet, but am interested in it. I’ve been reading up on it a bit on the blog called Mark’s Daily Apple.* I’ve been following it for several years now, even before Mark tried keto. Based on some of his blog post, both keto related and otherwise, it seems that women do better with slightly more carbs than men. He’s written several blog post specifically for women, including one called 7 Keto Tips for Women, which you may want to read. https://www.marksdailyapple.com/7-keto-tips-for-women/ Then there is this one Where I Part Ways with the Popular Keto Movement https://www.marksdailyapple.com/where-i-part-ways-with-the-popular-keto-movement/ Perhaps the problem wasn’t the keto diet in and of itself, but that you went too low carb for you. It’s worth considering. I’ve also found this site to be pretty interesting https://peterattiamd.com/ Here’s a link to his section on keto https://peterattiamd.com/category/ketosis/ He followed a ketogenic diet for a number of years, though as of 2016 was no longer ketogenic, but definitely eating lower carb than most. (That is under Articles, on the drop down menu, click on Personal.)
The Mediterranean diet has long been recognized as one of the healthiest and most delicious ways to eat. The core concept behind this healthy diet is to eat like the people who live in the Mediterranean region—fill your plate with fresh fruits and vegetables, healthy fats, whole grains, legumes and fish and enjoy moderate amounts of red wine. This 7-day Mediterranean meal plan features these good-for-you foods and delicious flavors for a week of healthy of eating. Plus, at 1,500 calories you're on track to lose a healthy 1 to 2 pounds per week.
Obviously, it’s still possible to lose weight on any diet – just eat fewer calories than you burn, right? The problem with this simplistic advice is that it ignores the elephant in the room: Hunger. Most people don’t like to “just eat less”, i.e. being hungry forever. That’s dieting for masochists. Sooner or later, a normal person will give up and eat, hence the prevalence of “yo-yo dieting”.
After 32 weeks, those in the keto diet group lowered their HbA1c more than those in the plate group with more than 50% achieving a reduction to less than 6.5%, basically reversing their diabetes. None in the plate group did this well. As for weight loss, those in the keto low-carb group lost on average of 28 pounds, while those in the plate group lost an average of 6.6 pounds.1
Net carbs is simply total carbs minus fiber and non-digestible sugar alcohols, like erythritol. (This doesn’t apply to high glycemic sugar alcohols, like maltitol.) We don’t have to count fiber and certain sugar alcohols in net carbs, because they either don’t get broken down by our bodies, are not absorbed, or are absorbed but not metabolized. (Read more about sugar alcohols here.)
Your New Year's resolution diet should be based on a well-balanced eating plan that fits your lifestyle, rather than a weird fad replete with food restrictions. That's according to U.S. News & World Report's best diet rankings for 2018. The two diets that tied for the top spot -- the Mediterranean Diet and the DASH Diet -- fit that bill because they feature real food and reasonable, flexible guidelines, experts said.
Adequate food records were available for analysis in a proportion of participants at each of the 4 timepoints (Table (Table2).2). Participants completed food records at a mean of 2.5 and a median of 3 timepoints. In general, comparing baseline to subsequent timepoints, mean carbohydrate intake decreased substantially and energy intake decreased moderately while protein and fat intake remained fairly constant.
Eggs are on the menu for days 3 and 6. Have a frittata made with two eggs, red bell pepper, scallion and 2 tablespoons of Parmesan cheese the first day. The next time you have eggs, break an egg into half an avocado, sprinkle with a little Romano cheese and bake. This not only cooks up fast, but offers you the heart-healthy monounsaturated fats of avocado.
A majority of the meal planning for the Mediterranean diet consists of fresh fruits and vegetables. A sample days meal menu consists of: a pumpkin-gingerbread smoothie for breakfast, Macaroni with Milk (Macoroni oil-Hali) for lunch, and Trout with Wilted Greens for dinner. Your suggested snacks during the day: Mango-Pear Smoothie, cashews and raisins, low-fat ricotta cheese with peaches, hummus, and seed and nut snack bars.
Cons: In our experience, capping your calories low will probably mean a lot of internal strife and stress. Plus, we’re big fans of enjoying food instead of fearing it, and 800 calories doesn’t leave much room for satisfied taste buds. Lastly, if you’re currently eating double to triple this amount of food, dropping to a daily caloric intake this low can tank your metabolism and actually slow weight loss more than switching to one of these other diets might. (Curious? Here’s why starving yourself won’t help you lose weight.)
Sautéed carrots and onions. Sauté 1 medium onion, thinly sliced, in 1 tablespoon olive oil or canola oil. Add about 8 ounces sliced carrots, and continue to sauté until the carrots are soft. Add 1 thin pat of butter at the end. (Hints: Top the turkey with the sautéed carrots for extra flavor. If you like very soft carrots, microwave first before sautéing.)
In 1993 Oldways created the Mediterranean Diet Pyramid – in partnership with the Harvard School of Public Health and the WHO – as a healthier alternative to the USDA’s original food pyramid. Today, the Mediterranean Diet is more popular than ever, with new research every month documenting its beneﬁts, and chefs and home cooks alike embracing Mediterranean ingredients and ﬂavors. Starting at the base of the pyramid, you’ll ﬁnd:
Keep eating low carb to continue losing weight, feeling good and becoming healthier!Try making any of our hundreds of recipes available on the site. We make sure each and every recipe is delicious, nutritious and will keep you under your daily carb limit, even if you go for seconds. In addition, we provide step-by-step instructions to make the process as easy as possible. If you ever run into any issues or have any questions, be sure to leave a comment or contact us directly! We’re always happy to help.
Dairy products such as cream and cheeses. They work well in cooking as they satisfy. The problem is if you’re munching a lot of cheese in front of the TV in the evening… without being hungry. Be careful with that. Or lots of cream with dessert, when you’re actually already full and just keep eating because it tastes good. Or another common culprit: loads of heavy cream in the coffee, many times per day.
“So many of us sacrifice this for work, family, or social experiences, but sleep is a basic tenet of health; you will not function properly, cognitively or physically, without adequate sleep,” Moreno explains. "Adequate usually means at least 8 hours. Set strict sleep time rules and practice good sleep hygiene. When you prioritize sleep, other aspects of good health may line up more easily.”
Kamut is an ancient grain native to the Middle East that is an excellent source of heart-healthy omega-3 fatty acids, protein, and fiber, while simultaneously being low in calories. In fact, a half-cup serving of the stuff has 30 percent more protein than regular wheat and just 140 calories. What’s more? A study published in the European Journal of Clinical Nutrition found that eating Kamut reduces cholesterol, blood sugar, and cytokines (which cause inflammation throughout the body). Kamut’s ability to stabilize blood sugar and reduce inflammation make it a great weight loss staple, especially if it is used in place of nutritionally lacking refined grains.
A: You’ll find a detailed menu earlier in this article (also, recipes from Everyday Health!), but generally, you’ll want to make plants and whole grains the stars of your plate. If you look at a Mediterranean diet food pyramid, sweets are up top (indicating they should make up only a small part of your diet), followed by meat and dairy, and then fish. Last are fruit, veggies, and whole grains (suggesting they can be eaten liberally). Also, enjoying food with friends and family is a tenet of the eating approach, so make your meals a social affair!
Some diet plans, such as the MIND diet and the DASH diet, are meant to focus on certain areas of health — and weight loss may be a bonus. Others are created with weight loss as a primary goal. “It is important to remember that we are all very unique individuals,” says Kyle. “We all have different states of health and different lifestyles, which could affect what diet plan is best for us. That means that you should not be considering what is working for your friends or family members — and instead should pay attention to what works for you individually.”
Need more tips to follow the DASH diet? You'll find a free guide that is full of meal plans, DASH diet food lists and recipes at the National Institutes of Health website. You'll also find a 7-day DASH Diet Eating Plan that guides you through a full week's worth of meals. If you want more help, there are other DASH diet guides online and DASH diet books that are available for purchase.
Most dieticians I have met are over rated and under educated. This article somewhat proves me out. Congratulations on your accomplishments. I have been in Ketosis for a couple of months now. I have lost 28 pounds. I feel great. No sugar No Bread Nothing from a box lol. Only good fats and Meats and good veggies(dark greens mostly) and a few macadamia nuts now and again and a few berries now and then. I think even the dieticians being human are also addicted to sugar and unable to give it up so they play down ketosis unconsciously because they are just jealous! lol
This is a great site for information, details, recipes, etc… one of the reasons I started looking into this way of eating is my husband suffers from high blood pressure, cholesterol and type 2 diabetes. We are not exceptionally overweight, however could both use to lose 10-15 lbs/ea. I also have facial and ocular rosacea and have heard good things about this way of eating for an overall improvement in numerous areas. Although I may have missed it I haven’t seen anywhere you might have mentioned your weightloss success. Thank you for sharing your wealth of information.
Because people with type 2 diabetes are at an increased risk for cardiovascular disease, there’s a specific concern that the saturated fat in the diet may drive up LDL, or “bad,” cholesterol levels, and further increase the odds of heart problems. If you have type 2 diabetes, talk to your doctor before attempting a ketogenic diet. They may recommend a different weight-loss diet for you, like a reduced-calorie diet, to manage diabetes. Those with epilepsy should also consult their doctor before using this as part of their treatment plan.


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Blog by Lexi Lutz
Our minds and bodies are intrinsically connected, so it should come as no surprise that our mental health can have significant effects on physical health. Good mental health can positively affect your physical health. Conversely, poor mental health can negatively affect your physical health. Challenges in accessing mental health care exist for everyone, which include cost, lack of insurance coverage, and stigma. Unfortunately, minority groups face unique challenges in accessing mental health care due to factors that are unique to minority groups, such as inability to find providers from one’s own racial or ethnic group, and stress caused by experiencing/witnessing racial discrimination or racial violence.
For some people, particularly in some minority groups, it is important to see a mental health care provider who is from their own racial or ethnic group. This can help to ensure that the provider can understands and empathize with the patient’s cultural background and experiences. It can be difficult, however, to find providers who are from minority groups in certain locations, especially in rural areas.
Additionally, a person who experiences or witnesses racial discrimination or racial violence can create mental health problems due to stress or trauma created by such situations. Minority groups are more likely to experience and witness racial discrimination or racial violence, putting minorities at higher risk for mental health issues caused by these unfortunate experiences.
Mental health care challenges are not exclusive to minority groups; however, minorities do face risk of unique factors that could create challenges to receiving mental health care that tend to effect minority groups more so than non-minorities. Support organizations that are working to improve access to mental health care for people from racial and ethnic minority groups include: National Alliance on Mental Illness (NAMI) (https://www.nami.org/) and Mental Health America; (https://www.mentalhealthamerica.net/).

domain: psychology


AFRICAN MUSIC CELEBRATION
Subtitled - The African Musical Celebration. This hit musical was first performed in Johannesburg in the early 70s. The songs were originally written for Eartha Kitt who was touring South Africa & wanted to sing songs of African origin. Ultimately, the songs were not used by Kitt, but composers Bertha Egnos & Gail Lakier were contacted by Australian promoters to transform the songs for a stage production to celebrate the South African way of life. Prestige Elite. 2002.
Audio Visionary Music ApS - Ryesgade 18, 1 - 8000 Aarhus C
Tlf. (+45) 86 13 73 43 - Email: firstname.lastname@example.org
All prices include 25% VAT -
Terms of business - CVR nr. 26-79-98-21
Audio samples on the website are offered with permission from KODA and NCB


The U.S. Senate plans to launch a meeting today for “Protecting Our Children Online,” an initiative aimed at safeguarding children’s online activities and protecting them from various forms of online risks.
Last year, there were over 21 million episodes of sexual exploitation against children by online predators. This can include improving online privacy and data protection, as well as restrictions on access to harmful or inappropriate content, and preventing online grooming and exploitation of children cyberbullying, inappropriate/pornographic content, and online sexual predators who aim to influence children.
The media and social media executives have decided to largely go the opposite direction, even going as far as to ban the use of the word “groomer.”
“Groomer” is a word for someone who uses various tactics to gain the trust of a child or young person with the intent of sexually exploiting them. However, the word to describe online predators was banned as a result of the instances of adult transgender people helping to normalize transgender ideology for children. As a result, the LGBTQ activists who intended to influence children were called groomers. In response, both Twitter and Reddit banned the word “groomer” in July of 2022, which
Today at 11:00AM: A Senate Judiciary Committee hearing to discuss protecting children online.
Tune in live: https://t.co/YDwvozTGTK
— Senate Judiciary Republicans (@SenJudiciaryGOP) February 14, 2023
In recent years, there have been several policy and legislative efforts by governments and organizations around the world to protect children’s online safety. In the United States, several bills related to child protection online have been introduced in the Senate, including the EARN IT Act, the PROTECT Kids Act, and the Online Safety Modernization Act. These initiatives aim to address various online risks faced by children and strengthen regulations and law enforcement efforts to ensure their safety online.
Hello? There is a way to protect kids online. It’s called PARENTS.
Social media…but not Porn? Porn is corrupting our children. It is devastating to them. 18 and a credit card to watch porn or none of the rest of this will have any positive effect. There is no good reason to allow children to access Porn. It needs to be stopped 1st.


Is NATO doing what it’s supposed to be and what should the main message be after the NATO Summit in Warsaw?
- Russian news site spreads misinformation about multinational military exercise taking place in Latvia
This Infographic shows who is taking part at the NATO Warsaw Summit 2016.
Everything you should know about behind the scenes at Warsaw 2016 on a simple Infographic
Both organisations share so many key security challenges (stemming from their shared membership) it is unsurprising that CSDP objectives significantly overlap with NATO’s strategic concept.


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Eco panel heaters use convection and radiant technology to draw cold air in and radiate warm air out, using less electricity than other room heaters. Wall mountable and light weight, they are easy to install and have a paintable surface to match any decor.
They are very economical, while other heaters can use up to 2000 watts, the ecosave panel only uses 425 watts.


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Tracy is quite new to Foodie Penpals, and I was really thrilled to be matched with her – it was great fun shopping for her. I got a good idea of what to send from our email chats and reading her blog (check out some of my favourite recipes – Salmon and Leek Parcels and Apple Samosas, and Slow Roasted Lamb). Pop on over to Tracy’s blog to see what I sent her.
Holly and I were a late pairing, but, I think, a very successful one. My parcel arrived, and as usual, in my childlike love of receiving parcels, I got straight in!
I have never received home baked goodies in the post before, and I love the salted caramel brownies – Holly’s talents are certainly put to excellent use in her business! I’m looking forward to working my way through this parcel. We have a bake off for charity coming up at work, so I am sure I will get good use out of the cake toppers, and I’m looking forward to making cola icing (maybe with vanilla cupcakes?). The balsamic pearls will be perfect with a salad – I’m a real balsamic fiend and would choose that over any other salad dressing.
I’ve asked Holly for the recipe for the brownies – I may attempt them for the bake off!

domain: hobby


Doubling of Food Poverty rates shocking - Crowe
After the Healthy Food For All Initiative today called on the Government to prioritise the critical issue of food poverty, Sinn Féin Spokesperson on Social and Family Affairs Seán Crowe TD echoed the Initiative's call on those in political power to urgently address this issue.
The Dublin South-West TD said: "The fact that almost one-fifth of the population is at risk of food poverty is a shocking statistic in an Ireland so proud of the 'Celtic Tiger'. While commentators regularly report on poverty figures and statistics, food poverty itself seems to have been comparatively ignored, but the problem is getting worse. In 2003, based on official national data on poverty, up to 10 per cent of the population were considered to be at risk of food poverty. It is of great concern that this figure has almost doubled in just three years.
"The connections between food poverty and poor health and educational attainment are stark. Four percent of people do without a meal containing meat, chicken or fish every second day, while over five percent of people were unable to afford a substantial meal on at least one day out of every two weeks. People having to do without valuable sources of protein are increasing health inequalities.
"Growing levels of health problems are linked to low income and poor diet, with the reliance on a cheap fast-food culture having detrimental affects for a significant proportion of people and contributing to the growth of obesity, especially among young people.
"I would support the Healthy Food For All Initiative's call on the Government to establish a fund for community food initiatives, such as the Fresh Food programme in Fettercairn in my own constituency."
Deputy Crowe also gave support to the call for a focussed increase in welfare payments to help address this issue.
"A 2004 report showed that up to 80 per cent of a person's welfare payments would be required to provide a healthy diet," he pointed out. "If the Government took on board the concerns of such groups as the Combat Poverty Agency and increased welfare payments, the eradication of food poverty in Ireland would become an achievable objective. We should not be in a situation where people have to choose between paying for food, for electricity or for medicine, but this is the reality for tens of thousands in Ireland today."


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India, a big fuel importer, might seem a natural destination for liquefied natural gas (LNG) from Qatar, but until this year such imports have not materialised.
Late last month, Qatargas and Royal Dutch Shell announced they had loaded their first cargo of liquefied natural gas (LNG) from the Qatargas 4 project. It was bound for India's west coast terminal of Hazira.
The development not only marked the culmination of Qatar's plans to become the world's biggest LNG exporter, with 77 million tonnes of annual production capacity, but also represented a vote of confidence in India's recent progress with its gas grid.
India is poised to transform its power sector away from coal and imported oil towards cleaner-burning natural gas with the help of newly discovered gas reserves and infrastructure.
"The mix will shift toward natural gas," says Manu Srivastava, the director of gas at India's energy ministry. "There's so much hunger for power and energy."
The country's lack of pipelines and import terminals, however, has prevented it from taking full advantage of the recent glut of gas on world markets. But things are changing.
Analysts and industry insiders say India needs to develop nationwide gas distribution capacity to back long-term supply agreements with major LNG suppliers such as Qatar. Until this year, however, there were few signs its government was serious about attracting investment for the five major pipeline projects needed to connect India's various regional gas pipeline systems.
"The gas market is driven by a pipeline network. That is a must," says A K Balyan, the chief executive and managing director of India's Petronet LNG. "We do not have a countrywide gas pipeline network and grid."
But now firm ministry plans are in place to increase India's trunk pipeline capacity by 50 per cent to 16,323km by the end of next year.
That could help India to capitalise on its proximity to Qatar. The Qatargas 4 project in particular was developed with the aim of opening up markets for Qatar's LNG sector.
"It is therefore fitting that its first cargo should go to India, a market with significant potential for LNG," says Andy Brown, the executive vice president of Shell.
Beyond importing more gas, India is seeking to boost domestic gas production and add new reserves.
At the end of 2009, the nation's proved gas reserves stood at a respectable 39.4 trillion cubic feet, slightly more than those of the Netherlands, which has large North Sea gas reserves.
Output of 3.8 billion cubic feet per day was India's highest in a decade, surpassing that of Turkmenistan, a major gas exporter with the world's fourth largest reserves.
An increasing number of analysts see this as the tip of the iceberg. Some predict India could become self-sufficient in gas within a decade, following the recent example of the US, which in the past five years has swung from regarding gas as a scarce national commodity to converting LNG import terminals into export facilities.
The problem is that new gas output in India would probably not come from conventional gas deposits that are easy to produce, but from unconventional resources such as deep gas, shale gas and coal-bed methane.
It would take decades for India to develop the home-grown expertise needed to exploit such challenging resources by itself, so it needs help from international partners.
Such help is on the way. Last month, just as Qatargas 4 launched its first LNG cargo towards India, BP and India's Reliance Industries, the country's largest private-sector conglomerate, struck a US$7.2 billion (Dh26.44bn) deal aimed at developing promising deepwater gas prospects in the Krishna-Godivari basin off India's east coast.
BP will take a 30 per cent interest in the 23 oil and gas oil and gas blocks to which Reliance holds the title. All but one, an onshore coal bed methane prospect, lie in water ranging from 400 metres deep to more than 3km in an offshore area about the size of New Zealand. The two companies will also form an alliance to market the gas in India.
In total, BP and Reliance could invest up to $20bn in gas development in coming years. In return for providing technical expertise in deepwater oil and gas operations, BP would benefit from Reliance's strong network of sales and marketing relationships within Indian government and private-sector circles.
Analysts are keen on the deal, calling it a "win-win" scenario for both parties. It also appears to have the blessing of India's government.
"BP coming to India is a validation of resources available in the country's oil and gas sector, particularly the east coast," S Sundareshan, the Indian oil secretary, told Dow Jones. "We have been wanting oil majors to come to India."
India is seeking to raise its domestic gas production by 21 per cent in coming years, says Mr Srivastava. BP's deep-sea drilling expertise would help advance that strategy, he indicates.
Mr Sundareshan says BP's presence in India could encourage wider participation in the country's next oil and gas bidding round. Companies have until March 18 to submit bids for the 34 blocks to be included in the nation's ninth such auction.
A third promising development last month was the completion of India's first shale well. It was a resounding success that has geologists and engineers already pegging the country's shale gas resources at between 600 trillion and 2 quadrillion cubic feet, equal to at least two centuries of gas supply at the country's current consumption rate.
New Delhi expects to launch India's first shale gas auction in August. Reliance is among the potential bidders.
The company recently acquired a stake in the huge Marcellus gas shale deposit in the north-east US and has applied itself to learning the technical side of the business.
* additional reporting by April Yee

domain: news


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The very private and very exclusive Maldives island resort of Coco Bodu Hithi is the perfect getaway for couples and groups alike.
Located in the stunning alps of Switzerland is this resort-esque home
To appeal to a new generation of skiers, resort operators are designing streamlined properties with special attention to amenities and connectivity for the digital age
Forgoing the usual method of simply selling a property, one Australian couple will be giving it away to one lucky winner.
London and Geneva may boast Europe’s highest costs of living but when it comes to luxury hotels, Italian and Greek cities are in a league of their own.

domain: geography


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Food industry funding influences research, according to an investigation published in JAMA Internal Medicine. The authors uncovered correspondence and other documentation that exposed the sugar industry’s influence on scientific results. An accompanying commentary published in the same journal supports these findings with a historic overview of various industries’, including meat and dairy, attempts to skew research in their favor.
Kearns CE, Schmidt LA, Glantz SA. Sugar industry and coronary heart disease research: a historical analysis of internal industry documents. JAMA Intern Med. Published online September 12, 2016.
Nestle M. Food industry funding of nutrition research: the relevance of history for current debates. JAMA Intern Med. Published online September 12, 2016.
WARNING: This post is not skewed by funding influences!
Nutrition Tip of the Day
Avoid eating while you are distracted – by watching TV, driving, or checking e-mail. Distraction during mealtimes can lead to overeating since you will be less focused on hunger signals and the amount of food you’ve eaten.

domain: medical


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On April 17, 2018, “Hasta” a solo exhibition by the Portuguese artist Francisca Carvalho was inaugurated at Crafts Museum, New Delhi.
“Hasta” is an exhibition of paintings on cloth with natural dyes, Kalamkari and Hand Block Printing.
The exhibition shall remain open to public up to April 29, 2018.
Timings: Tuesdays through Sunday, 10 a.m. to 5 p.m.
Venue: Crafts Museum, Pragati Maidan, New Delhi

domain: artistic


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Online edition of India's National Newspaper
Friday, Nov 11, 2005
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KOCHI: The Kerala History Association has condoled the death of the former President K.R. Narayanan. In a condolence message, president V.R. Krishna Iyer and secretary E.P. Antony said that Narayanan was a leader who led India in a most critical stage, keeping up the spirit of the Constitution.
Dakshin Bharath Hindi Prachar Sabha also condoled the death of K.R. Narayanan. In a message, sabha vice-president Vakkam N.Vijayan said that his demise was a national loss.
Expressing condolence at the death of the former President, Nationalist Youth Congress State committee said that he had upheld the tenets of secularism even amidst the most negative circumstances. Carmelites of Mary Immaculate Prior General Antony Kariyil also expressed condolence at the death of K.R. Narayanan. The Kerala Chamber of Commerce and Industry also expressed its condolence.
The chamber executive committee said that the death of Narayanan was a great loss to Kerala and to India. The National Council of YMCAs of India South West India Region condoled the death of Naryanan. Kerala State SC/ST Coordination Forum vice-chairman P.K. Kumaran condoled the death of the former President.
Mahathma Gandhi Trust, Kochi, also condoled the death of the former President. Trust general secretary M.K. Kandoran, in a statement, said that he was the founder patron of the trust.
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Storm slams Southern California as Central U.S. faces winds, fire threat
Several U.S. states were under threat from more extreme weather overnight, as heavy rains in Southern California caused flooding and mudslides — triggering mandatory evacuation orders and sparking rescue operations Tuesday.
Threat level: A "rapidly strengthening storm system" was set to generate high winds from the Southwest to the Upper Midwest, with gusts "up to and in excess of 75 mph in some areas," per the National Weather Service. The Southern and Central Plains face "abnormally high temperatures" and the threat of wildfires, the NWS said.
What's happening: Heavy rains from a moderately strong atmospheric river event saw several rescue operations launched along the swollen Los Angeles River on Tuesday, after several Orange County residents became trapped by mudslides, per the Los Angeles Times.
- Evacuation orders were issued for several communities in O.C., as mudslides and flooding threatened areas scarred by wildfires, the Orange County Register reports.
- While evacuation orders were lifted late Tuesday, firefighters continued to patrol the area overnight, the Orange County Fire Authority said.
What to watch: High wind watches and warnings were in place from the Desert Southwest to the Upper Midwest, where widespread power outages were expected.
- Days after the deadly tornadoes that pummeled the Central and Southern U.S., the NWS warned there could be more twisters in the new storm system, with a slight risk of severe thunderstorms over parts of southern Minnesota and northern Iowa, effective Wednesday through Thursday.
- Winter storm watches, warnings and advisories were in effect from the West Coast through the Rockies, with widespread heavy snowfall forecast to persist over the western U.S. through Thursday.
By the numbers: More than a foot of snow was set to accumulate in the mountain ranges of the Central Great Basin and Northern and Central Rockies overnight.
- Another round of heavy snow was set to hit the Sierra Nevada and neighboring Cascades on Wednesday afternoon, with snowfall accumulations of 8-12 inches expected.
Meanwhile, "record-breaking heat" was likely to impact the Central and Eastern U.S. through Thursday, the NWS said.
- Unseasonably warm weather, strong winds, extremely dry fuels and low relative humidity levels were set to strike the Central and Southern Plains over the next few days, "producing highly favorable conditions for the spread of wildfires," according to the weather service.
- The NWS said much of the Texas and Oklahoma Panhandles faced a "Critical Risk of Fire Weather" through Wednesday morning.


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Jennie Linden (born 8 December 1939) is an English film and television actress. She is best known for her starring role in Ken Russell's classic Women in Love (1969), as well as her starring role in the cult film Nightmare (1964).
|Alma mater||Central School of Speech and Drama|
|Parent(s)||Marcus and Frieda Fletcher|
Life and careerEdit
Linden was born in Worthing to Marcus and Freida Fletcher, respectively an architect and a housewife. She attended the Central School of Speech and Drama at the age of 17 on a scholarship. Her classmates included Julie Christie and Vanessa and Lynn Redgrave.
Her earliest film appearances were as the heroine in Hammer's Nightmare (1964) and Barbara in Dr. Who and the Daleks (1965). Her most widely known film role was as Ursula in Women in Love (1969), for which she received a BAFTA nomination; a year later she appeared opposite Lee Remick and Ian Holm in the film version of Iris Murdoch's novel A Severed Head. Her subsequent film appearances include Vampira (1974), Valentino (1977) and Charlie Muffin (1979).
Wishing to raise her son in England, Linden decided not to pursue a career in Hollywood. She was considered for The Lion in Winter (1968) and The Go-Between (1970); the latter was for the lead role of Lady Marian Trimingham, for which Julie Christie was later cast. She turned down the role of Amy in Sam Peckinpah's Straw Dogs (1971).
Linden toured in Trevor Nunn's Royal Shakespeare Company production of Hedda Gabler for two years playing Thea Elvsted, with Glenda Jackson in the title role; they later appeared together in the 1975 film adaptation.
Linden's television credits include The Avengers (episode: Lobster Quadrille, 1964), Sherlock Holmes (1965), The Saint (1966), The Persuaders! (episode: To the Death, Baby, 1970), The Rivals (1970), The Adventures of Black Beauty (episode: "Foul Play", 1973), Little Lord Fauntleroy (1976), Lillie (1978) as Patsy Cornwallis-West, Tales of the Unexpected (episode: "Pattern of Guilt", 1982), Lytton's Diary (1985), Chancer (1990), and Trainer (1991). She continues to do different roles and can be found on TV and stage. She is married to Chris Mann; they have a son, Rupert.
- Nightmare (1964) - Janet
- Dr. Who and the Daleks (1965) - Barbara
- Women in Love (1969) - Ursula Brangwen
- A Severed Head (1970) - Georgie Hands
- Pogled iz potkrovlija (1974) - Linda Channing
- Vampira (1974) - Angela
- Hedda (1975) - Thea Elvsted
- Valentino (1977) - Agnes Ayres
- Charlie Muffin (1979) - Edith
- Stevens, Christopher (2010). Born Brilliant: The Life of Kenneth Williams. John Murray. p. 401. ISBN 1-84854-195-3.
- "I Never Wanted to Be a Woman In Love: As the BBC Updates a Classic Drama, Jennie Linden Reveals Why...", Daily Mail, 27 March 2011.


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G-Dragon I’m also influenced by the issue of one person
G-Dragon I’m also influenced by the issue of one person in the public
G-Dragon expressed his thoughts on the issue.
Vogue Korea has released a Paris pictorial with G-Dragon. On the 15th, Vogue Korea delivered an interview with G-Dragon under the title “G-Dragon’s new chapter: ‘I’m always curious about my interests, too.’
G-Dragon caught the eye with his colorful curls. G-Dragon with pink hair wore a colorful tweed jacket. G-Dragon showed off his unique charm by presenting various looks.
G-Dragon said, “G-Dragon is an artist who is always curious about his interests. When asked if there is a book, movie, or artwork that has recently caught your attention, he replied, “I read a lot of books and watch two movies a day.” “I love reading, and it’s really fun to get new inspiration. In fact, I’m also always curious about my interests,” he even showed his honesty.
As a curious person, there are so many things that make me curious and interested in this world. G-Dragon, who showed his frankness, said, “As time goes by, my interests expand and my thoughts on art become more diverse.” He also showed his affection for his fans without hiding anything.
When asked, “What is the power that has led you as a musician as a human being?” G-Dragon replied, “It’s different every moment, but as a human Kwon Ji-yong, my dreams and values are the driving force, and are similar as a musician, but our fans are the biggest.” “I can do music not only so far but also in the future because there are people who love me and listen to my music. As I kept trying to protect the standards, absolute values and precious people I set, I was able to pay more attention and do better,” he said, showing his love for his fans.
G-Dragon also spoke frankly about his thoughts on the issues of the day As a popular singer, I think it’s something I can’t not care about. It’s a category called “trend,” so it’s a way to communicate and communicate with fans and the public in its own way rather than care,” G-Dragon said. “I’m also a member of the “public” who learns directly and indirectly about these issues, and is motivated and influenced by the good side. I’m curious about the flow of this moment. Instinctively, this is the part where the radar is the best among the thoughts and emotions I have.”
Meanwhile, G-Dragon recently made headlines over rumors of a romantic relationship and a breakup with Jenny of BLACKPINK.

domain: celebrity


About the Coalition
Founded by residents for residents, we are a collection of concerned individuals that want the city to follow the existing zoning regulations and neighborhood overlays that allow for balanced growth, affordable housing and a respect for the city and its environs.
As the advantages of Asheville become more apparent and growth moves into our area, our community is now threatened by proposed developments that constantly seek (and are awarded) conditional zoning variances that alter our natural and historic character as well as put unimagined pressure on our infrastructure and vehicular traffic in the area. Currently, there are two proposals moving towards a vote in the City Council; if approved it will add 400 families and 50,000 square feet of retail space on the corner of the already congested Charlotte and Chestnut Streets.
The Coalition supports smart growth, and the revitalization of the Charlotte Street corridor, but current plans – the precedent it sets for development on the rest of Charlotte St – are unmanageable and untenable.
Charlotte Street is a gateway to multiple historic communities
The Proposed 101 Charlotte Street Development violates the directives in the Asheville Unified Development Ordinance (UDO) and the Charlotte Street Transition Overlay District, and does nothing to help ease the affordable housing crunch
While disrupting a whole neighborhood and displacing the current renters of affordable housing in development area, at the end of the day, the city is actually losing affordable housing from what’s there, or what could be provided by just following the Overlay.
Density outside the norm
According to the recent Bowen report there will be about 3200 additional households in the city by 2024. The two projects at Charlotte St represent close to 400 of those households, meaning that 12.5% of that total will be crammed on an already over-burdened road. The city is considering these actions without any consultation with the residents, nor any explanation as to the plans for infrastructure improvement, traffic management, etc. The neighborhood should be involved in the discussion on such a wide ranging, neighborhood altering plans.
The Proposed Development will push local infrastructure to the breaking point
Old water lines on Charlotte, Furman and Baird are between 4” and 6” wide and Chestnut Street’s are only 16” wide. Water impermeability is already 45%; with one new development, that number rises to 80%. Charlotte Street already suffers from much standing water during rains, this will make it immeasurably worse. Further, traffic congestion has already increased due to Charlotte Street’s “road diet.” Adding 180+ residential units and 50,000 sf of commercial space will crush traffic in that area.
Click here to see the size of the proposed development
Charlotte Street as an “Innovation District?”
Charlotte Street was selected – along with the River Arts District and the South Slope – as an Innovation District. While South Slope and the River Arts District are prime areas for overhaul and growth, Charlotte Street, Grove Park and Chestnut are more established and developed neighborhoods. While the ACSG can support the smart growth of an Innovation District, the massive “over-investment” in this concept will have repercussions to the almost 4000 families that live in the 28801 zip code. Further, while North Charlotte Street has proximity to downtown, South Charlotte Street is actually downtown, and there is ample city owned land to utilize, stretching from the Public Works at Beaumont Street to Biltmore Avenue.


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Alphabet E Coloring Pages
Please don t forget to check out the rest of.
Alphabet e coloring pages. Exploring e s is easy. Free alphabet letter e coloring page this free english coloring page can be used two ways. Letter e letter f letter g letter h letter i letter j letter k letter l letter m letter n letter o letter p letter q letter r letter s letter t letter u letter v letter w letter x letter y letter z abc coloring abc games abc tracers other sites. Look at the newspaper and grocery coupons.
You can choose the images you. For boys and girls kids and adults teenagers and toddlers preschoolers and older kids at school. Coloring the alphabet is a good way to introduce the youngest learners to letters of the alphabet through an activity they like. You can print the coloring.
Free printable alphabet coloring pages can help you with that. It is the grouping in a specific order of the spellings used to represent the language that serves as a communication system. Coloring page index alphabet index coloring pages for kids alphabet coloring pages upper case lower case and cursive prev 10 next 10. The theme of each letter is from our popular alphabet flash cards.
Alphabet coloring pages we hope you enjoy these abc coloring pages. Get the coloring pages of the letter e on this page. Super coloring free printable coloring pages for kids coloring sheets free colouring book illustrations printable pictures clipart black and white pictures line art and drawings. Alphabet e showing 12 coloring pages related to alphabet e some of the coloring page names are individual alphabet letters s alphabet e letter e to and for how much do you like the letter b letter e is for elephant pin by melissia harmon on alphabet 25 best.
E is the fifth letter of the alphabetic letter. Alphabet coloring pages for preschool kindergarten and elementary school children to print and color. Free alphabet letter e coloring printable. Kindergarten preschool worksheets if you are a parent who wants your child to learn the alphabet you can take a look at these worksheets.
These alphabet coloring sheets are great for kids and preschoolers as they help them recognize and memorize the alphabets and learn new words. Use crayola markers to circle all the capital e s and use a different color to circle lower case e s. All english coloring pages including this alphabet letter e coloring page can be downloaded and printed.
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Hotels in Seine et Marne
Seine et Marne Hotels
People who come to stay in Seine-et-Marne walk along the banks of the Marne River. They also come to this region to pay a visit to Fountainebleau and the Disneyland Resort, Paris. These ventures take longer than a weekend. Seine-et-Marne, always inviting, entices visitors by offering up the 12th century ramparts of Provins as well as the Museum of the Prehistory of the Island of France. Beyond Disneyland, there is a lot to explore. Connect with the past in Fontainebleau. Visit the ChÃ¢teau de Fontainebleau. In composite styles, this structure features a Romantic garden with a bronze statue fountain of the Goddess Diana and her hound. Stop and admire the Tour CÃ©sar with its pyramidesque roof. Venture to Maincy to see the ChÃ¢teau de Vaux-le-Vicomte with its Louis XXXI style and gardens by AndrÃ© Le NÃ´tre.


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Fab 'n' Funky Challenge Blog! This week it is 's turn to host the challenge for the Fab 'n' Funky Team and she picked the fun challenge 'Halloween'!
For my card I
decided to use this super sweet and darling image Girlz - Witchy from our fabulous sponsor this week, Bugaboo Stamps!
had so much fun working with this image. I simply love Halloween and these wonderful 'Girlz' stamps Jodie has been releasing! I paired this image with the super cute Doodlebug Halloween Parade paper and added lots of layers plus this fun bow!
Be sure to stop by the Fab 'n' Funky Challenge Blog and join in on the fun there as well! I can’t wait to see what you create! Have a wonderful day all!
Stamps: Girlz - Witchy from Bugaboo Stamps; Paper: Whisper White, Orchid Opulence, Only Orange, Doodlebug Designs Halloween Parade DP; Ink:E34 Orientale, YG09 Lettuce Green, RV21 Light Pink, YR07 Cadmium Orange, N1 Neutral Gray No. 1, N3 Neutral Gray No. 3, V25 Pale Blackberry, Y13 Lemon Yellow, E00 Skin White; Accessories: Pop Dots, Gingham Ribbon, Self Adhesive Pearls


What clients are saying about Vector Praxis
"Julian and I spent considerable time working out design details over the phone. I had no difficulty conveying physical details to him and completely understood what Julian was trying to get across to me. If the reader has been in a similar situation, he is well aware that this can be an extremely difficult process……
I worked with Julian on a dozen high-profile projects since 2003 and almost every job won an award. His obsession with quality and understanding of construction process are a good fit for the NYC and US market and I can recommend him to anyone needing help with a complex project.
Julian led a machine tool modernization project in Latin America. Through Julian’s efforts, Olympia successfully bought and rebuilt heavy machine tools in Cuba, as well as importing machines and technicians to support Olympia’s work in Canada. The resulting products were sold to customers in Canada and Latin America. Julian knowledge of machine tools, import / export processes and his ability in English / Spanish commercial translation were all invaluable to the business.
It has always been a pleasure working with (Julian). The projects we have worked on with you have often been structurally and geometrically complex. The level of detail, awareness of manufacturing and imaginative approach to solutions that you have brought to the designs has always been critical to the success of the projects. I also appreciate that you have always been fair in your commercial dealings with my firm.
I hired Julian to design and build broadcast sets for News Theatre and later for CBC Newsworld and BNN. Despite short deadlines, demanding technical requirements and tight budgets he came through with the right look every time.
(Julian) is extremely intelligent, hard-working, and innovative. He is fair, reasonable and perceptive. It is a pleasure to work with him.
I can recommend him for his expansive knowledge of design and fabrication techniques (and) his remarkable attention to detail and quality.
Julian consistently surprised me with his insight and rapid grasp of the issues facing our firm in the commercialization of advanced robotics and his intuitive ability to “package” the technology effectively in customer-facing environments. Julian thrives on seemingly insurmountable challenges, delivering unique, efficient and robust solutions that meet or exceed diverse client needs
Julian and I…collaborated on a variety of commercial projects. His ability to see the big picture makes him a breeze to work with and is key to his ongoing success. He leads projects with a clear and determined vision.
I worked with Julian on the implementation of prefabricated washroom units (for) the BOW….. I found Julian to be a dynamic team leader with exceptional knowledge of building materials, process assembly and building information modeling
Julian was always…focused on the end result, collaborating and ensuring the designers vision came to reality……his thorough technical expertise and his ability to troubleshoot and ensure delivery of a completely functional solution was always consistent…..available, suggesting alternatives…..value engineering sensitive to managing a client’s budget and often exceeding designer’s expectations
….never met anyone as intelligent or as adept at solving technical problems…. always utilizing the conceptual underpinnings of the original design as reference ……I can think of no better partner than Julian Bowron


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Irish themed 9 Pots of Gold slot from Gameburger Studios available at all Microgaming casinos.
9 Pots of Gold is the third slot developed by Gameburger Studios and Microgaming and is a clone of their previous slot called 9 Masks of Fire. Therefore, if you have already played 9 Masks of Fire, then it will not be difficult to understand the gameplay of 9 Pots of Gold (9 Pots of Gold).
The 9 Pots of Gold slot machine is equipped with five reels and 20 lines to form your winnings. On these reels, you will see many familiar symbols such as the pot of gold, the golden harp, the top hat and many more, each with a different value.
There are quite a lot of betting options in 9 Pots of Gold, ranging from 0.20 cents for users playing at lower stakes, up to a maximum of $60, which is more suitable for the needs of high rollers. The RTP is 96.24%, the volatility is medium and the max win in 9 Pots of Gold slot can be up to x2000 of your initial bet.
In the 9 Pots of Gold slot machine, you will find two bonus features that will make the gameplay more interesting.
Free Spins feature - it comes into play when scatter symbols land on the second, third and fourth game reels. As soon as this happens, a Bonus Wheel divided into segments will appear in front of you, with the help of which you will find out the number of free spins available to you, as well as the multiplier. Here's what you can get:
Please note that the scatter symbols continue to land during the round, which means that if three scatters appear on the reels, they will again trigger the original number of free spins.
The second feature is called Pot Pays and is linked to the Scatter Pot symbol. Every time at least three of these symbols appear on the playing field, you get an instant cash prize. You can win 1x, 5x, 15x, 40x, 100x, 500x and 2000x bets when 3, 4, 5, 6, 7, 8 or 9 Pot symbols land.
Concluding, I would like to say that 9 Pots of Gold is quite a worthy and interesting slot machine, if not for one thing, but. It is an exact copy of the already existing 9 Masks of Fire slot by the same developer, only with a different theme.

domain: game


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You can play tennis at a nearby location, and the area is popular for horse riding, hiking and water skiing. Cahors is 21 km from Le Mas de Laval, while Figeac is 32 km from the property. Rodez is a 45-minute drive away.
Features of Le Mas de Laval • Free parking • Private parking • Bottle of water • Breakfast options
A full breakfast buffet is served daily at Hotel Saint-Cirq and guests can enjoy it on the terrace overlooking St. Cirq Lapopie or in the hotel’s dining-room in front of the fire place. At dinner time, there is a free shuttle service for...
Features of Hôtel-Spa Le Saint Cirq • Free parking • Private parking • Hiking • Cycling
Hostel Le Refuge Du Célé offers pet-friendly accommodation in Cabrerets. The hostel has a seasonal outdoor pool and views of the river, and guests can enjoy a meal at the restaurant. Free private parking is available on site.
Features of Hostel Le Refuge Du Célé • On-site parking • Restaurant • Outdoor pool (seasonal) • Swimming pool
You can play tennis at the property, and free use of bicycles is available. Rocamadour is 40 km from Gite La Riviere, while Cahors is 27 km away. The area is popular for horse riding and cycling. The nearest airport is Brive Dordogne Valley Airport,...
Features of Gite La Riviere • Pets allowed • On-site parking • Garden • Bikes available (free)
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domain: travel