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Central America Education Strategy: An Agenda for Action - World Bank
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Police in Congo Republic have shot dead four protesters during a demonstration against a constitutional referendum that could open the door for the long-time President Denis Sassou Nguesso to a new term in office.
The clashes in Brazzaville on Tuesday erupted after authorities banned a protest rally against the referendum on Sunday.
Politicians campaigning against the October 25 referendum have called for a campaign of “civil disobedience.”
Through the referendum, the president seeks to scrap the limit of two presidential terms and change a regulation preventing candidates older than 70 years to run for president.
According to the Interior Minister Raymond Mboulou, the “organized and coordinated insurrection” had led to three fatalities in the capital Brazzaville and a fourth in the southern town of Pointe-Noire.
Three members of the security forces were also seriously injured and 16 arrests were made in Brazzaville.
Amnesty International condemned the use of force and demanded authorities to refrain from using excessive force against protesters.
“A heavy-handed response by security forces not only violates the protesters’ rights to freedom of expression and peaceful assembly, but may enflame an already tense situation,” said Ilaria Allegrozzi, Amnesty International Central Africa researcher.
“The United States strongly urges all parties, including both the government and the opposition, to engage in dialogue and to refrain from violent actions that would undermine the hard-won peace that all citizens deserve,” Sarah Sewall, under-secretary of state for civilian security, democracy and human rights, said at a press conference in Kinshasa.
The 71-year-old president is barred from seeking re-election when his second term expires next year. He was elected into office in 1997 and had previously ruled Congo from 1979 to 1992.

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US Navy captures suspected pirates in Gulf of Aden(Read article summary)
The seven men arrested will be turned over to Kenya, which plans to set up a court to try pirates.
Jason R. Zalasky/US Navy/Reuters
The Navy Times reports that Vella Gulf personnel searched the suspects' skiff and found several weapons. The Navy plans to transfer the suspects to a US supply ship in which a hold has been outfitted as a makeshift prison guarded by Marines, before transferring them to authorities in Kenya, which is setting up a new court system to try foreign pirates.
The International Maritime Bureau said last month it had recorded 111 attacks in the waters off Somalia in 2008, nearly double the number in 2007. Other estimates run higher because ship owners don't always report hijackings.


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There’s nothing substantively different about Paltrow’s new single and all of the other “country and proud of it” songs that are out there. If it was recorded by any other new female singer that didn’t have an established public persona, it wouldn’t even raise an eyebrow.
The last few years of country music have so conclusively moved toward artifice that most country artists are already faking it. Alongside all the former pop stars and homegrown country artists who sound like them, it’s no surprise to see actual actors pulling off their country music efforts. The game has been moved to their turf, and they’ve got home court advantage.
So sure, she’s only acting. But aren’t they all?
Listen: Country Strong

domain: artistic


Epic. Operatic. Bombastic. Over-the-Top. Bonkers. Those are just a few of the words that recur in reviews and discussions of the work of the late composer, producer, and performer Jim Steinman. Though he’s most well-known as the composer of one of the best-selling albums in history, Meat Loaf’s Bat Out of Hell, Steinman had a career that encompassed rock, film, and musical theater. He wrote classic hits for the likes of Bonnie Tyler, Air Supply, and Barry Manilow, and his work with Meat Loaf plays endlessly on classic rock radio. Steinman died in 2021; today, on what would have been his 75th birthday, we look back at the Wagner, vampires, and velocity of his timeless brand of symphonic rock.
15. “No Matter What” by Boyzone (1998)
Like Andrew Lloyd Webber, Jim Steinman has never been beloved for his subtlety. In 1998, the pair collaborated on the musical Whistle Down the Wind. As a further collaboration that tied in with the musical’s premiere, the popular boy band from Ireland, Boyzone, recorded their version of the track. It went #1 in the U.K. and was the group’s only tune to crack the U.S. Top 40. The gentle ballad is a positively restrained version of Steinman, but the lyrics incorporate his usual swooning romanticism.
14. “Read ’Em and Weep” by Barry Manilow (1983)
Over his long career, Steinman would frequently reconfigure or rewrite old songs or ideas for use by other artists. This song originally appeared on Meat Loaf’s 1981 album Dead Ringer, but Steinman made some alterations for Manilow. Whatever Steinman did, it worked; Manilow took the song to #1 on both the Canadian and U.S. Adult Contemporary Charts. It was also Manilow’s last U.S. Top 40 hit to date.
13. “You Took the Words Right Out of My Mouth (Hot Summer Night)” by Meat Loaf (1977)
When Meat Loaf and Jim Steinman got to work on Bat Out of Hell, they had the odds against them. They’d faced rejection from a number of labels and stinging rebukes from the likes of Clive Davis, who didn’t get Steinman’s orchestral approaches. Nevertheless, when they got their chance to make the record, they made the most of it. The album features several legendary rock talents in key roles: Todd Rundgren produced and played guitar on five tracks; Edgar Winter played sax on three; and Roy Bittan and Max Weinberg of Bruce Springsteen’s E Street Band contributed on keyboards and drums, respectively. The whole album is an ode of sort to teenage love, lust, and motorcycles, and this track typifies that. It was the first single from the album, and didn’t make the Hot 100. However, after two other tracks were hits (just wait), it was re-released and made the U.S. Top 40.
12. “Two Out of Three Ain’t Bad” by Meat Loaf (1977)
Another from Bat Out of Hell, this was Meat Loaf’s biggest single until the next item on the list arrived over 15 years later. Rundgren and Bittan also played on this tune. Though it’s a bit simpler than other Steinman tunes, it’s got his patented subversive wit with lines like, “I want you/I need you/There ain’t no way I’m ever gonna love you/Now don’t be sad cause two out of three ain’t bad.” “Two” spent almost six months in the Hot 100, hitting #11 and selling over a million copies.
11. “I Would Do Anything for Love (But I Won’t Do That)” by Meat Loaf (with Lorraine Crosby) (1993)
Jim Steinman and Meat Loaf worked together on six albums, but it wasn’t until 1993 that they officially “sequelized” Bat Out of Hell with Bat Out of Hell II: Back into Hell. Steinman saw the lyrical territory as a definitive continuation of the themes of that album. Other musicians returned, like Bittan and Rundgren (though this time Steinman produced and Rundgren arranged the background vocals while also performing them on eight tracks). The song is a duet between Meat Loaf and Crosby, credited on the record as “Mrs. Loud.” It plays with many of the same dynamics as the original Bat tracks, including driving piano, defined movements between musical sections, and dueling dynamics (loud/soft/loud). Those sweeping sections that roar up out of almost nowhere have gotten Steinman compared to the German composer Richard Wagner, best known for The Ring Cycle, particularly “Ride of the Valykyries.” The verses of the final two minutes are mostly sung by Crosby.
10. “Good Girls Go to Heaven (Bad Girls Go Everywhere)” by Pandora’s Box (1990)
Another tune recorded by multiple artists, “Good Girls” was first done in 1986 by Japanese artist Megumi Shiina. In the late 1980s, Steinman assembled what was considered a “girl group,” Pandora’s Box, which featured a number of vocalists whom he’d worked with before. They included Ellen Foley (featured on Bat Out of Hell), Holly Sherwood (from the group Fire Inc.), Elaine Caswell (The Dream Engine), Gina Taylor (Musique), Deliria Wilde, and Laura Theodore. Sherwood took the lead on this track, which careens between the frenzied bounce of Steinman’s piano and the guitar of Eddie Martinez. Meat Loaf would record the song again for Bat Out of Hell II: Back into Hell.
9. “Nowhere Fast” by Fire Inc. (1984)
Director Walter Hill’s cult classic film Streets of Fire is identified as “A Rock & Roll Fable” right on the poster. The movie follows singer Ellen Aim (Diane Lane), who is kidnapped by gang leader Raven Shaddock (Willem Dafoe); Aim’s ex, soldier Tom Cody (Michael Paré) leads the effort to rescue her. The soundtrack is suffused with great material, including Dan Hartman’s huge hit, “I Can Dream About You.” Lane visualizes two different Steinman tunes in the film, including opening number “Nowhere Fast.” To record the two songs, Steinman put together a group, Fire Inc., which included a number of his usual suspects (Bittan, Weinberg, Sherwood) and Laurie Sargent, who handled lead vocals.
8. Bonus Pair: “This Corrosion” (1987) and “More” (1990) by The Sisters of Mercy
The English rock band The Sisters of Mercy formed in 1980. Their one constant member has been lead singer Andrew Eldritch, and he’s always resisted the “Gothic” label that has followed the band. Nevertheless, those trappings frequently appear in the band’s music, including two collaborations with Steinman. Steinman produced the Eldritch-written “This Corrosion” from 1987’s Floodland, and he wrote More for 1990’s Vision Thing. The two tunes are a perfect marriage for Steinman’s approach (there is no such thing as “over the top”) and Eldritch’s dark aesthetic. “Corrosion” in particular features a 40-piece choir.
7. “Bat Out of Hell” by Meat Loaf (1976)
The epic title track from the album that sold 40 million copies, “Bat Out of Hell” takes listeners on a journey through streets of terror on the back of a motorcycle that’s destined for a fiery end. You can understand comparisons that the record drew to Springsteen’s “Born to Run,” but Meat Loaf’s ride has a much more fatalistic bent. Whereas Springsteen implores his song’s Wendy to “get out while we’re young,” Meat Loaf expresses the belief that if he “gotta be damned, you know I want to be damned, dancing through the night with you.” You know the crash is coming, but the ride there is exhilarating.
6. “Holding Out for a Hero” by Bonnie Tyler (1984)
The Welsh wailer Gaynor Sullivan is better known by her stage name, Bonnie Tyler. She would put her distinctively smoky voice to many Steinman tracks over the years, but one of the best known is this part of the Footloose soundtrack. Steinman wrote the song with Dean Pitchford (the writer of the Footloose screenplay and co-writer of hit songs like “Fame”) and produced it for the soundtrack. Tyler took the song Top 40 in the U.S. and to #2 in the U.K. That same year, E.G. Daily did a version that was used for the TV series “Cover Up.” It’s since appeared in a number of other films, including Shrek 2.
5. “Making Love Out of Nothing at All” by Air Supply (1983)
Graham Russell of England and Russell Hitchcock of Australia formed Air Supply in 1975. Beginning in 1979, they had a string of hits around the world with songs like “Lost in Love,” “Every Woman in the World,” and “Even the Nights Are Better.” They’ve racked up a number of gold and platinum albums and had 11 Top 40 hits in the U.S. “Making Love Out of Nothing at All” went all the way to #2 in 1983 and sat there for three weeks, denied the top spot by . . . just wait. While the soaring vocals of Hitchcock fit right in with the tune, Steinman brought in Bittan, Weinberg, and guitarslinger Rick Derringer to up the epic quotient.
4. “It’s All Coming Back to Me Now” by Celine Dion (1996)
Determined to top himself with the “most romantic, most passionate” song he was capable of making, Steinman composed “It’s All Coming Back to Me Now” for Pandora’s Box. The composer was inspired by the novel Wuthering Heights and its themes of love surviving death. Elaine Caswell sang the version on the 1990 Pandora’s Box album, Original Sin. A few years later, Celine Dion would cover it for her album Falling Into You. Dion, who often shows the same disdain for subtlety as Steinman, embraced the song’s epic nature and let fly for nearly eight minutes. The tune stayed at #2 for five weeks in the U.S., held back by (regrettably) “Macarena” and (we’ll let this slide) “No Diggity.” The single sold more than two million copies. In 2006, Meat Loaf covered it as a duet with Marion Raven on Bat Out of Hell III: The Monster is Loose.
3. “Tonight Is What It Means to Be Young” by Fire Inc. (1984)
The climactic tune of Streets of Fire, “Tonight Is What It Means to Be Young” was sung by Steinman’s frequent collaborator Holly Sherwood. The song wasn’t released as a single and wasn’t a hit, but it’s an outstanding example of Steinman at the height of his powers. It’s become a beloved cult tune, reappearing in Fire’s low-budget sequel, Road to Hell, and has even been covered by show choirs. It’s also the final song in a very special stage musical, which we’ll address in a bit. The song is quintessential Steinman with its long build, revving engines, and increasingly explosive vocal heroics.
2. “Paradise by the Dashboard Light” by Meat Loaf with Ellen Foley (1976)
Without a doubt, this was late New York Yankees announcer Phil Rizzuto’s finest musical hour. The Hall of Famer makes an immortal appearance in the middle section of the song, giving a play-by-play that mirrors the male protagonist’s attempt to “score.” Meat Loaf sang his part at full tilt, while Ellen Foley provided the alternately encouraging and suspicious female lead (Karla DeVito, who sang with Meat Loaf live on stage for the tour, is seen in the video). The song went Top 40 in the U.S., and then basically never left rock radio. It’s widely regarded as one of the great duets in rock and has certified sales of a million singles. Of course, it’s one of the engines that drove Bat Out of Hell to 40 million copies sold. It’s epic structure and length, Todd Rundgren’s terrific guitar, and the last minute narrative twist make it a stone-cold classic.
1. “Total Eclipse of the Heart” by Bonnie Tyler (1983)
The following is one of this writer’s favorite bits of music trivia: “Total Eclipse of the Heart” was originally written for Steinman’s long-gestating vampire musical. Steinman wanted to do a musical based on the F.W. Murnau silent horror film classic, Nosferatu (itself an unauthorized adaptation of Bram Stoker’s Dracula). For various reasons, that would never come together.
Bonnie Tyler entered the picture in 1981. She’d already had hits like 1977’s “It’s a Heartache,” but she wanted to work with Steinman after seeing Meat Loaf live. The third song that Steinman pitched to her would be “Total Eclipse of the Heart.” Tyler recorded it for her album Faster Than the Speed of Night. Among the musicians were, no surprise, Derringer, Bittan, and Weinberg.
The song was a worldwide smash. The aching ballad hit #1 in the U.K. and the U.S., where it topped the charts for four weeks. Its stay held “Making Love Out of Nothing at All” to #2, but put Steinman in the rarified company of writers (like Lennon/McCartney and Barry Gibb) who got to hold #1 and #2 simultaneously. The single sold more than six million copies. It’s been covered numerous times; in 1995, English singer Nicki French stormed the U.S. charts with her hi-NRG cover, taking it to #2.
Like other Steinman songs, “Total Eclipse of the Heart” has never gone away. It’s stuck around in films, commercials, and on the radio. And though the lyrics could clearly be interpreted as having more than a little to do with vampires, many people dismissed the song’s origin as an urban legend. It seemed like that story would eventually fade, even though it certainly inspired the Dracula musical that’s a running bit in the 2008 comedy Forgetting Sarah Marshall.
Steinman realized a different version of his stage musical dream in 1997. With German writer Michael Kunze, Steinman took part in mounting a vampire musical in Vienna. Tanz der Vampire was adapted from the classic Roman Polanski film The Fearless Vampire Killers, also known as Dance of the Vampires (the musical’s name was the German version of that title). Steinman included a number of his songs, with a German twist, in the production. The closing number was a version of “Tonight Is What It Means to Be Young.” But the mid-point showstopper, the first song of Act II, was “Total Finsternis,” the adapted version of “Total Eclipse of the Heart.”
The musical was a big hit in Europe. An attempt to bring the show to Broadway was botched by too many parties that wanted it to be too many things; the compromised English version closed in January 2003 after fewer than 56 performances. But overseas, the show endured, and through 2020 many productions were mounted across a number of countries. Steinman would fare far better in 2017 when Jim Steinman’s Bat Out of Hell: The Musical launched. The show features most of Steinman and Meat Loaf’s classic tunes; the show has a residency in Las Vegas and is set to tour Europe and Australia through 2023.
Obviously, the music of Jim Steinman isn’t for everyone. Yes, it’s operatic and melodramatic and occasionally the finest type of cheese. But it’s emotional, swooningly romantic, and shot through with the spirit of rock and roll. Though he died last year, Steinman achieved the kind of immortality that eludes all but the most supernatural of talents. The songs broke out of his body and flew away . . . like a bat out of hell . . . and popular music was all the better for it.


text:
Why It's Sexist to Feel Bad for Selena Gomez After Bieber's Engagement
4 monthes ago - By StyleCaster
Where were you when you found out Justin Bieber got engaged? Correction: Where were you when you found out Justin Bieber got engaged to someone who is not Selena Gomez? I was minding my own business on the subway while mindlessly scrolling through Instagram. Suddenly, my thumb stopped and hovered over Bieber's Instagram post where he referred to his 21-year-old fiancée Hailey Baldwin as the “love of his life.” I immediately sent
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Selena Gomez Heads Back to Work With Rumored Younger Boyfriend in Tow
4 monthes ago - By TMZ
Selena Gomez is keeping herself busy - on the heels of her ex-boyfriend Justin Bieber's engagement announcement - by throwing herself back into acting, and she's not doing it alone. Gomez was seen Thursday on the set of the zombie-com "The Dead...
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Tristan Thompson Calls Son Prince His ‘Twin' In Touching Birthday Post: I'm...
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Ellen DeGeneres Considering Ending Daytime Talk Show In Near Future
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Here's How to Get Drawn into an Episode of ‘BoJack Horseman'
The creators Netflix 's hit animated series BoJack Horseman are offering fans the chance to be drawn into an episode if they're willing to donate to a good cause. "You're gonna...

domain: celebrity


TGIT: Are You Ready For The Scandal-HTGAWM Mash-Up Happening Tonight?
Fans couldn't be more excited. Hit the flip and tune into ABC at 8pm EST.
Posted March 1, 2018
Susanna Osborne, more affectionately known as Sukii, serves as an Associate Entertainment Editor for iOne Digital. The Spanish Harlem native got her start in blogging back in 2010 when she began covering Hip Hop’s rising stars for GlobalGrind. Music (and entertainment at large) are spaces Sukii continues to focus on as a writer, but her pen game knows no bounds. Since starting at iOne Digital in 2014, the Spelman College alum has contributed to the majority of iOne brands, often venturing into controversial topics such as women's rights, sex, and race relations. Follow her on Instagram and stay tuned. @KingSukii
RELATED TAGSAnnalise Keating how to get away with murder Kerry Washington olivia pope scandal tgit Viola Davis


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The year 2010 is going to be a pretty big one for South Africa, with the eyes of the sporting world on the country for the football World Cup.
The tournament kicks off in June, so to get an idea of how preparations are going across the country, Newsround has sent Ore to South Africa to find out more about the country.
"You have to do plenty of research and planning before a trip like this to South Africa, but there are some things you just can't prepare yourself for.
One of those things was seeing what an amazing city Cape Town is. It was helped by the 30 degree heat and clear blue skies that greeted us, but it's definitely one of the nicest I've ever been to.
Table Mountain dominates the city's landscape and it has some beautiful beaches and a really lively harbour. I'm so glad to have got the chance to visit.
Robben Island prison
The reason behind Newsround's visit to Cape Town was to get to Robben Island which, up until the early 1990s, was a high-security prison.
It might sound unbelievable, but for decades South Africa was a country that forced black and white people to live completely different lives. This was called apartheid
Black people weren't allowed to vote, and most of them lived in poverty - you'll find out more about it in the Newsround South Africa Special on Friday 8 January.
People who tried to go against the government and apartheid were sent to the prison on Robben Island.
One of those people was former South African president Nelson Mandela. He was locked up there for 27 years.
The cells aren't much bigger than a toilet cubicle and as former inmate Thulani was telling me, life there was really hard.
But he explained how a man like Nelson Mandela was an inspiration to all the prisoners on Robben Island.
I found it really difficult seeing the conditions people had to live in for such a long time in history just because of their race.
Back in Johannesburg, I met 11 year-old Dumisani. He lives in an area called Soweto, but like many of the areas surrounding South Africa's big cities, the people have to make do with the bare minimum - small shack-like houses, no running water and very little food. The poor conditions mean that disease can spread.
Dumisani and his mum
As an only child, Dumisani is the only one to look after his sick mother. She only has one lung and has to use an oxygen pump to survive. Dumisani told me that as hard as life is, one day he wants to be a lawyer or a doctor.
But there are some projects out there that help kids like Dumisani. I joined one called Starfish for the day. They go around the country offering food parcels to take home as well as giving them activities to do during the day.
Charities like this give the kids hope that they can achieve something. Someone like Dumisani has high hopes and I hope that one day he can reach those goals."

domain: geography


Michelle Williams Checked a Fan for Giving Unsolicited Advice
It seems that when you’re in the public eye, everyone feels like it’s their job to tell you how to live, what to wear, and apparently even when to have kids. When an Instagram user left a comment on Michelle Williams’ post suggesting that it was time for the singer to have kids and make her life more interesting, the star snapped back. She simply responded, “You’re an idiot!” but the interaction didn’t end there.
The user replied, saying to Michelle that her comment was uncalled for, to which she responded with a lengthy explanation. She educated the commenter on why a person should never tell a woman when she should have children. Williams continued by explaining how some women may not be able to have kids, or motherhood might not be something they want altogether. The Instagram user then replied, apologizing for speaking out of turn, adding that they “would never forget that.”
Michelle Is Currently Going Through a Breakup
Williams was recently engaged to Pastor Chad Johnson in 2018, but the pair have since ended the engagement and called it quits. Michelle is in the process of healing after the breakup and has opened up about battling depression. She said that a person must be persistent in order to deal with depression and that she is a living testament of not giving up.
Knowing her heartbreak, it makes so much more sense why that foolish comment may have hurt Michelle Williams even more. At least she handled it like a badass and used the occasion to educate a fan.


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One of the most challenging and intriguing questions in plant pathology is to understand how plant pathogens interact with both their host plant and the environment (including vectors and other micro-organisms) in order to provoke major diseases, sometimes turning to epidemics. Such knowledge is used to stimulate and foster innovative strategies and technologies for a sustainable biological control of tropical and temperate plant diseases caused by bacteria, fungi or viruses.
Our team develops diagnostic tools to monitor plant diseases caused by these biotic agents and to predict epidemics. We study pathogenesis, biotic interaction and epidemiology of plant diseases. We characterize the biodiversity of populations involved in the various patho-systems in order to improve their control using environmentally friendly strategies.
Via our extension services, we provide cutting-edge advice on plant diseases and control strategies to producers and consumers, in close connection with both research and training.

domain: agronomy


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Thanks to my friend Vincent for tipping me off to this, the first of a weekly video podcast from Steven Reynolds and Dartagnan on the card magic of Ed Marlo.
Why would you want to learn card magic off someone who got caught doing a double lift for years, and years, and years?
I don’t care if you think I’m being cruel by thinking these videos are funny but come on, who in their right mind wouldn’t find his facial expression at 2:30 bloody hilarious?!
First saw this at –
He’s so patronising it makes you cringe yet he’s also unintentionally very very funny!
A larger scale version of a trick based on ideas by Jon Armstrong, Matthew Bich and Marv Long.
The miniature version of the plunger is a very comical prop with lots of scope for personalised routines –


Harrisburg—Legislation sponsored by State Senator John DiSanto (Dauphin/Perry) requiring the General Assembly to approve all major regulations was approved by the Senate Intergovernmental Operations Committee this week.
Senate Bill 520 ensures no regulation or revision to general permits with economic impacts, or costs to government or the private sector, exceeding $1 million could be imposed without legislative approval. This change would protect businesses, non-profits, and individuals from costly, burdensome regulations.
The existing regulatory review process only allows the General Assembly to pass a concurrent resolution disapproving a regulation. However, a governor must sign the disapproval resolution to bar an agency from enacting the regulation, a highly unlikely scenario, Senator DiSanto noted.
“The people expect their elected representatives, not unaccountable government agencies, to make laws” DiSanto said. “Lawmakers must ensure state regulators are adhering to legislative intent because overly restrictive rules have severe impacts on our residents—especially following the economic stress associated with COVID-19.”
With committee passage, Senate Bill 520 moves to the full Senate for consideration.
CONTACT: Chuck Erdman 717-787-6801 email@example.com


Fourier transform tandem mass spectrometry (MS/MS) provides high mass accuracy, high sensitivity, and analytical versatility and has therefore emerged as an indispensable tool for structural elucidation of biomolecules. Glycosylation is one of the most common posttranslational modifications, occurring in ∼50% of proteins. However, due to the structural diversity of carbohydrates, arising from non-template driven biosynthesis, achievement of detailed structural insight is highly challenging. This review briefly discusses carbohydrate sample preparation and ionization methods, and highlights recent developments in alternative high-resolution MS/MS strategies, including infrared multiphoton dissociation (IRMPD), electron capture dissociation (ECD), and electron detachment dissociation (EDD), for carbohydrates with a focus on glycans and proteoglycans from mammalian glycoproteins.
Keywords: Tandem mass spectrometry, Electron capture dissociation (ECD), Electron detachment dissociation (EDD), glycosylation, infrared multiphoton dissociation (IRMPD), oligosaccharides, Electrospray ionization, Dimethyl sulfoxide, Ultraviolet photodissociation, Peptide-N-glycosidase F, Nuclear magnetic resonance, Negative electron transfer dissociation
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Knowledge science employs ideas and methods of data analysis, machine studying and statistics to derive an understanding and evaluation of the data related phenomenon. High-affinity T cells show a small but crucial kinetic advantage compared to low-affinity T cells at early time points, i.e., 36 and 48 hours after T cell activation, thus mirroring the kinetic differences of vitality technology ( Fig. 3Biochemistry, Cellular, and Molecular Biology Graduate Program, Johns Hopkins College College of Drugs, Baltimore, MD 21205, USA.
Microchannel networks were seeded with human umbilical vein endothelial cells (HUVECs) as a result of our previous research demonstrated that inclusion of endothelial cords improved tissue engraftment ( 38 ). We then evaluated whether or not optimized bioengineered liver tissues would survive transplantation in a rodent model of chronic liver harm.
Together, these data point to a mechanism of action the place DHODH inhibition corrects metabolic disturbances in T cells, which primarily affects profoundly metabolically energetic excessive-affinity T cell clones. In fact, grouping of cells based mostly on the diploma of IRAK1 clustering was capable of predict oscillatory habits ( Fig.
Ranging from houses, eating places and workshops to factories, offices and faculties, know-how can be found everywhere as of late. In practical phrases, the recent findings on student attitudes to STEM subjects, their perception of scientific work, and the move of STEM graduates to their discipline of expertise, could also be improved by positively altering the way in which governments, scientists, and educators talk science on a day-to-day level.
The Carnegie-Mellon Examine took into account the differences of what engages feminine students and modified the Computer Science programs curriculum so that the context for the program was taught a lot earlier on in the semester and moved some of the extra technical points of the curriculum (such as coding) to later in the semester.
According to the Nationwide Curriculum, the instructing of science at Keystage 1 and 2 includes providing youngsters alternatives to develop information and understanding of vital scientific concepts, processes and expertise and relate these to on a regular basis experiences. The invention of light-regulated domains to manipulate signaling has opened up the thrilling chance of concurrently measuring and perturbing signaling dynamics in single cells ( 27 , forty six ). To determine the molecular mechanisms resulting in TLR and IL-1R tolerance and dose-response perform, we used two new optogenetic instruments, OptoTRAF6 and OptoMyD88, to stimulate signaling at different nodes in the community.
The IoT is a community of bodily units, together with things such as private health screens, sensible appliances, and autonomous transportation techniques, that are embedded with digital technologies that enable the devices to work together with each other by collecting and communicating knowledge ( 5 ). It has the potential to additional remodel human lives with functions together with good electricity grids, sensible houses, sensible cities, well being monitoring, transportation system control, and environmental management ( 1 ). The IoT can even affect power manufacturing and use, which is able to in turn affect the environmental impacts of the power system.
For example, positivist social scientists use methods resembling those of the natural sciences as tools for understanding society, and so define science in its stricter trendy sense Interpretivist social scientists, against this, might use social critique or symbolic interpretation relatively than developing empirically falsifiable theories, and thus treat science in its broader sense.
Once more, shifting feminine students (and the non-techsavvy scholar generally) to turn out to be downside solvers (versus just understanding the content piece of the STEM puzzle) will move them to make use of greater order pondering expertise in STEM.
What Can You Do With A Computer Science Degree?
The function of science and technology from the space analysis to the identification and exploration of the mineral resources is highly commendable. Collectively, these information do not solely present mechanistic insight into the molecular mechanisms of how TCR alerts that consequence from antigen-particular interactions of certain affinities may be translated into distinct intracellular packages but additionally explain the differential effect of DHODH inhibition on high-affinity and low-affinity T cells.
However, the general fields of science (or ” pure philosophy ” as it was known as) and far of the overall knowledge from the traditional world remained preserved through the works of the early Latin encyclopedists like Isidore of Seville 55 Nevertheless, Aristotle’s authentic texts have been ultimately misplaced in Western Europe, and only one textual content by Plato was widely identified, the Timaeus , which was the only Platonic dialogue, and one of many few original works of classical pure philosophy, out there to Latin readers within the early Center Ages.
ΚB Signaling Dynamics Is Controlled By A Dose
It improves the productive level of individuals and staff because Folks’s information of life beyond the world they lived in is now unlimited.
With the arrival of science and expertise, new innovations have come ahead making life more comfortable for us, bringing different forms of leisure at our fingertips and their easy accessibility ensures that the consumers take pleasure in them utterly. 5C ). This IRAK1 aggregation was extremely heterogeneous between isogenic cells and depended on TLR or IL-1R signaling, as a result of TNFα didn’t aggregate IRAK1 (fig. Chance, statistics, and machine studying come underneath the scope of Mathematical side while utilized elements enable you to gain data of information science, languages which incorporates Python, MATLAB, JAVA, SQL.
First, to judge the impact of teriflunomide on CD4+ T cells, we made use of myelin oligodendrocyte glycoprotein (MOG)-specific T cells from 2D2 mice, that are identified to cross-react with a specific neurofilament (NFM15-35) peptide ( 11 ), with a higher affinity than their cognate MOG35-fifty five peptide ( 11 ). Teriflunomide was more effective in restricting proliferation of CD4+ T cells upon excessive-affinity stimulation in comparison with low-affinity stimulation in vitro ( Fig.
Both preclinical information and datasets from clinical trials illustrate the impact of pharmacological DHODH inhibition on lymphocyte proliferation and enlargement ( 1 , 3 ). As illustrated by a not too long ago revealed placebo-controlled trial ( four ), it is nonetheless poorly understood how these medicine exert a selective effect on autoreactive T cells whereas only barely affecting immune responses in opposition to micro organism and viruses.
3 a: knowledge or a system of data covering basic truths or the operation of general laws especially as obtained and examined via scientific technique b: such data or such a system of information concerned with the physical world and its phenomena.
Science, Expertise, And Financial Improvement
Science and expertise is the very best factor society may ever ask for. With a patient’s own stem cells now (from the patients pores and skin, no embryos needed) obtainable they will then convert them into any cell within the physique and replicate them. The reason being that individuals want to acknowledge that there are people who find themselves affected by the science and technology.
In keeping with a report launched on Could 16, 2013, in a serious medical breakthrough, scientists have for the first time converted human pores and skin cells into embryonic stem cells. The typical workday of particular person scientists have been transformed as a result of creativity, imagination and onerous labor that goes in the analysis within the discipline of science and expertise.
Science Projects For 4th Grade
We reside in a highly sophisticated world where every thing is sort of achievable. Further experiments revealed that a structurally distinct DHODH inhibitor, brequinar, exerted comparable affinity-dependent effects on T cell proliferation (fig. Equally, within the training sector too, the affect of the developments in science and expertise is very commendable.
These newly made stem cells are able to remodeling into every other cell kind within the human physique. In December we needed to get an thought how the scholars felt about Careers in Science, Expertise, Engineering and Arithmetic before the day of the event. The fertilised egg cell then develops and ultimately produces stem cells.
science lab msds, Science & Technology, science society malang
If we look life one hundred years in the past, and evaluate that with the at this time’s life, we will discover that Science has dramatically changed human life. Mechanistically, teriflunomide-mediated inhibitory results on T cell proliferation depended on OXPHOS inhibition, and their extent was closely linked to antigen affinity, because excessive-affinity T cells exhibited a better dependence on OXPHOS than low-affinity T cells.

domain: biology


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Do Deep Promotional Discounts Work? New Study Sheds Light on Strategy
FAYETTEVILLE, Ark. – Many retailers employ discounts to attract customers, but it can be difficult for businesses to know what effect these discounts have on overall store performance, and few studies have analyzed store-level data to know for sure whether this strategy works.
A new study published in the Journal of Retailing shows that promotional discounts increase store traffic and lead to higher overall profits, especially if the advertised products are staples – items such as meat and produce that are purchased frequently and by many customers.
“Our results validate the widespread use of price promotions supported by feature advertising, such as those found in newspaper circulars,” said Dinesh Gauri, professor of marketing in the Sam M. Walton College of Business. “These featured promotions provided a beneficial impact on several key performance metrics, including store traffic, sales and profits.”
Over a 49-week period, Gauri and co-authors Brian Ratchford at the University of Texas at Dallas, Joseph Pancras at the University of Connecticut, and Debabrata Talukdar at the University of Buffalo analyzed data on 27 product categories from 24 branches of a popular Northeastern grocery chain. Each week, the authors compiled data on overall traffic, sales per transaction, and profit margin for each store.
They examined the impact of so-called “loss leader” strategies – the practice of deep promotional discounts to attract customers who will buy other items – on several product categories, including penetration (items bought by many people), frequency (frequently purchased items), storability (items that can be stored, such as paper napkins or plates), impulse items and national brand items.
Their analysis of about 677,000 transactions, with an average value of $15.44 per transaction, showed that deep discounting, accompanied by a blitz of advertising promotions, achieved retailers’ goal of attracting more customers into stores and increasing overall profits. But the researchers’ main finding came with several caveats, Gauri said.
Promotional discounts on both high-penetration, high-frequency items (staples such as meat and produce) and low-penetration, low-frequency items (beer and condiments) led to increased traffic but lower sales per transaction.
“This suggests that these promotional discounts tend to attract small-basket customers,” Gauri said.
However, discounts in these same categories were associated with higher overall profit margins, especially in the low-penetration, low-frequency category. Gauri said this suggests that the smaller transactions generated by the discounts contained an above average number of high-margin items, in addition to the discounted items.
“We think this result was driven mainly by beer, which was featured almost every week,” Gauri said.
These other findings can also give retailers an edge, the researchers said:
- Broad discounting in one category may lead to diminishing returns.
- On average, discounts on national brand items had a stronger impact on per-transaction sales than discounts on non-brands.
- Consumers who took advantage of deep discount promotions on impulse products tended to buy products in more profitable categories.
About the University of Arkansas: The University of Arkansas provides an internationally competitive education for undergraduate and graduate students in more than 200 academic programs. The university contributes new knowledge, economic development, basic and applied research, and creative activity while also providing service to academic and professional disciplines. The Carnegie Foundation classifies the University of Arkansas among only 2 percent of universities in America that have the highest level of research activity. U.S. News & World Report ranks the University of Arkansas among its top American public research universities. Founded in 1871, the University of Arkansas comprises 10 colleges and schools and maintains a low student-to-faculty ratio that promotes personal attention and close mentoring.
The American Association for Access, Equity and Diversity, the oldest operating association of professionals in equal opportunity profession, named Danielle Williams the recipient of the President's Award.
Sophomore Gary Jackson has been selected as the Student Leader of the Month for November 2021. Originally from Pocahontas, Arkansas, Gary came to the U of A to study biology and chemistry.
Karli Stringer, a graduate student, examined the relationship between nutritional habits and religious views for her master's thesis, finding that Christian beliefs didn't necessarily translate to healthy eating.
The food pantry's cookbook is available digitally or as a physical copy for a donation of $25 or more. A donation of $50 or more will also sponsor a holiday meal kit for a client of the pantry.
Students Advocating Stronger Sisterhood will host a canned food drive from noon to 2 p.m., Monday, Dec. 6, in front of the Food Court at the Arkansas Student Union.

domain: news


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GLP and cGMP Analytical Chemistry Services
Employing state-of-the-art instrumentation in HPLC, GC, and mass spectrometry, VxP Pharma develops analytical chemistry methods from initial concept to validation and can verify or improve existing methods for the analysis of a wide range of active compounds. All analytical services can be provided to meet GLP/GMP guidelines (or non-GLP as requested) for both small molecule and large molecule programs.
Method validation is an important part of the overall qualification process that establishes, through rigorous testing, that the performance characteristics of the method meet the requirements of the intended analytical application. Method validation provides an assurance of reliability of laboratory studies during normal use, and is sometimes referred to as the process of providing documented evidence that the method does what it is intended to do. In addition to being good science, regulated laboratories must carry out method validation in order to be in compliance with governmental and/or other regulatory agencies. A well defined and documented method-validation process not only satisfies regulatory compliance requirements, but also provides evidence that the system and method are suitable for their intended use.
An effective analytical method development process involves evaluating and optimizing various method parameters to satisfy the goals of the procedure; a properly developed and optimized method can help to insure its success upon implementation. Many different approaches to method development have evolved, however the basic premise of changing selectivity to effect a separation that satisfies requirements of the method is the common theme. A comprehensive method development approach also often involves forced degradation studies, robustness development, standard addition, and other pre-validation studies performed to insure the resulting method can be validated.
At VxP Pharma, we have extensive experience with Method Development, and Method Validation, as well as meeting FDA, GMP, and ISO requirements.
The state-of-the-art labs are staffed by some of the best trained and most experienced subject matter experts in the field.

domain: literature


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Following the initial release of 2,891 documents previously withheld by the Central Intelligence Agency (CIA) relating to the assassination of President John F. Kennedy on Thursday, October 19, the Internet went up in storm. While many are satisfied with this initial release of documents regarding the president’s assassination, the international non-profit transparency group WikiLeaks is offering a $100,000 reward for the remainder of the withheld documents, with founder Julian Assange calling President Trump’s delay on the 25-year-planned full release “inexcusable.” As an interesting example of cosmic irony, 2017 also happens to be the centenary anniversary of President Kennedy’s birth, and while the Mint has not yet produced any commemorative coins to celebrate this occasion, two individual citizens have taken it upon themselves to do so. Citizens Coinage Advisory Committee (CCAC) member Heidi Wastweet and former CCAC chairman Gary Marks cooperatively produced a one-ounce silver medal to commemorate the centenary anniversary of the fallen president’s date of birth. While most of the country appears to be fussing over the details of President Kennedy’s death, it seems that only a few are bringing attention to his birth, life, and accomplishments.
Artist Gary Marks echoed exactly the same sentiment when I interviewed him by e-mail. “I feel JFK’s birth centennial went largely unnoticed by the American public,” he wrote.“My medal was my small contribution to raise awareness and to once again honor this great man.”
He also brought attention to the nature of this American tragedy and how it conversely inspired him to commemorate the president in a positive light. “When I realized about a year ago that the 100th anniversary of JFK’s birth would be on May 29, 2017, I knew I needed to create a silver art medal to honor this great American. His untimely death was a great tragedy and loss for America. It was the untimeliness and the loss of a great man that served as the central theme of my inspiration for the medal. I felt the empty profile in the center of the obverse was the perfect emblematic device to convey the sentiment that he was ‘gone too soon.’”
Current CCAC member and prolific artist Heidi Wastweet also shared her thoughts with me via e-mail regarding the creation of the Kennedy medal. “I was both thrilled and apprehensive when Gary invited me to work on his project. Excited because it’s a great design and topic, and because I enjoy working with Gary. Apprehensive because many other great sculptors have made masterful portraits of Kennedy in the past. I needed to honor the man himself as well as all the sculptors who came before me. Making a portrait of a public figure is especially difficult because everyone has their own idea of what that person looks like.”
The 1-ounce silver medal has a mintage limit of just 1,000 pieces and runs for $51.95 at “Gary’s Midnight Insomniac Art Studio” website.
The obverse features an effigy of the president juxtaposed against his shadowy profile. Inscriptions read JOHN F. KENNEDY and BIRTH CENTENNIAL at the top, while the years 1917-2017 are displayed along the bottom.
The reverse displays a perched eagle with a quote by President Kennedy: “WE SHALL PAY ANY PRICE. . . TO ASSURE THE SURVIVAL AND THE SUCCESS OF LIBERTY.” Additionally, the inscription JFK can be seen below the quote, while 1 OZ AG is displayed underneath the eagle.
To any who possess a further interest in the popular field of Kennedy medals and commemoratives, The Kennedy World in Medallic Art by William R. Rice is one the foremost texts on numismatic Kennedy memorabilia. Kennedy medals are an extremely popular topic in the collector community to this day, which is exactly why it is shocking that so few have taken advantage of the coinage possibilities for the centenary anniversary of his birth. Perhaps due to our almost Victorian obsession with death, we’ll have to wait until 2063 to get more centenary anniversary medals of President Kennedy, but thanks to artists Gary Marks and Heidi Wastweet — we can enjoy an excellent centenary medal right now.


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Whatstandwell Bridge, Cromford Canal, Main Road, Crich, built to take the pre-existing Crich to Wirksworth turnpike road over the Cromford Canal, completed in 1794.
'A simple bridge constructed of local rough coursed gritstone. The string course follows the line of the deck. The bridge has a stilted arch, the parapets and battered abutments curve and splay, and it has flush half-round copings. It is wider between parapets than other Cromford Canal bridges and has longer wider curves to the parapets on the south-east and north-west sides terminating in rounded piers. The other tow piers are 'standard Cromford' square. The bridge rises from the west to the east. The line of the canal copings continues as a string course under the bridge on the offside. The towpath passes under the bridge on the west bank. Arched recesses in the bridge narrows indicate 'Brindley Gates'. The bridge was built to take the pre-existing Crich to Wirksworth Turnpike road over the canal.' (1)
From the National Heritage List for England:
'SK 35 SW PARISH OF CRICH MAIN ROAD 3/31 Canal Bridge GV II
Canal overbridge. Late C18. Coursed rubble gritstone, with single semi-circular arch incorporating roughly shaped voussoirs, but without a keyblock. Plain band above arch head, and shallow rubble parapet walls with half round copings. The bridge tapers in width from west to east, and has splayed abutments. The Cromford Canal was opened in 1793, its engineer being William Jessop.
Listing NGR: SK3324954316.'
Listed Building File: Historic England. 2011. The National Heritage List for England. https://historicengland.org.uk/listing/the-list/list-entry/1109170?section=official-list-entry.
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SK 33249 54316 (point)
CRICH, AMBER VALLEY, DERBYSHIRE
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Derwent Valley Mills
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domain: history


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Grilling is considered as the best hobby that you can do in your entire life. The term grilling is used to show that it is the quick process of cooking a raw fish or meat on the coals directly. Usually, the thinner slices of meats, such as hot dogs hamburgers, and chicken breast are being grilled. Grilling is also one of the excellent ways that you can do to cook your favorite veggies. Are you looking for the reasons why grilling is a good hobby? Then, keep on reading this article.
Benefits of Grilling as a Good Hobby
You can Grill even You are Busy
Grilling is one of the best hobbies that you can do that will enable you to sit back, relax, and enjoy drinking some beverages with your friends. It is also a hobby that can be performed during summer and warm spring days.
Veggies Cooked on Grill are the Best
Almost all people don’t think that veggies that are on the grill can remain their minerals and vitamins. And this is very true in terms of low water content vegetables.
You will Use Lesser Butter
If you are an expert hobbyist in grilling, you will not overcook your desired meats and foods. Plus, you can have juicier meats and savory vegetables without using much butter. Since the grill will lock lots of moisture, you tend not to use any condiments that will jazz your food up. It only means that you will consume lesser amount of calories and avoid putting unhealthy things inside your body as well.
Nutrient Retains in Meats
When you throw a slice of beef onto the coals, thiamine and riboflavin are retained. And these two nutrients are very important for you to have a healthier body. Thiamin and riboflavin can also give you plenty of health benefits.
You will Eat Lesser Fat
When you do grill, you will eat a lesser amount of fat since the fats will leak onto the racks. Think of yourself making some burgers using your grill versus pan. You can notice that the fats will cook off when it was cooked with grills on fire. On the other hand, you can see the fats of burgers around your pan. Thus the meat will re-absorb it.
I hope that the reasons mentioned above are enough to encourage you to do grilling as one of your favorite hobbies.

domain: food


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Happy 6th Birthday Graham
chocolate, chocolate filling, vanilla mousse
Just wanting to send along a BIG (late) thanks for the wonderful cakes you made for us. Both were ABSOLUTELY scrumptious. Just the best! And each Thank you, too, with being able to accomodate the late notice...and special deliveries.


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In this section, we focus on the wealth of cultural paths that wind their way through the entire Rhine-Main region. Arranged thematically, these paths are intended more as sources of inspiration than as actual directions and offer readers the opportunity to discover the metropolitan region in their own particular way. On this page, the routes will gradually be expanded and the range of them extended. Feel free to submit your own suggestions to firstname.lastname@example.org!
This route follows RMV’s LRT Line 8, offering passengers access to all the cultural institutions along the line between Wiesbaden and Hanau without the need for a car. In terms of subject matter, this route offers a potpourri of contemporary art and design in the Rhine-Main region. Click here to access the route!
The five magical stops on this cultural route are mainly devoted to the life and works of the famous collectors of stories from North Hessen, demonstrating just how important Jacob and Wilhelm Grimm still are to the region. Click here to access the route!
You don't have to go to Italy or Greece to get an authentic insight into the life of the Romans, Greeks or Celts - a trip through the Rhine-Main Metropolitan Region is enough to experience antiquity at first hand. To follow in the footsteps of antiquity, please click here!
This route features museum gems of the metropolitan region that have dedicated themselves to very special and unusual themes. From watering cans to pinball machines - you can discover these specialities of the region here!
The institutions on this route are dedicated to collecting and exhibiting the medium of photography. Klick!
The importance of viticulture for the development of the region is shown by the museums on this route. In addition to the history of viticulture, historical and current cultivation and extraction methods as well as the role of the mild climate in the region are highlighted. Click here to access the route!

domain: travel


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Lou Dorsey, a paralegal in Legal Aid’s Upper Shore office (Easton), was awarded the 2008 William L. Marbury Award at the Maryland Legal Services Corporation’s annual awards reception last night in Baltimore. “A heartfelt thank you to you all,” said Dorsey, who was given the award by Court of Appeals Chief Judge Robert M. Bell and MLSC chair F. Vernon Boozer. “I’ve always loved the law … I’m proud to play a small role in helping low-income Marylanders get access to justice.” The award recognizes a non-attorney who has demonstrated outstanding service in Maryland representing the rights and legal needs of the poor. “In his 12 years with Legal Aid, Mr. Dorsey has demonstrated excellence in client communication and support of other staff,” Boozer said. In the photo (left to right): MLSC executive director Susan Erlichman, Bell, Dorsey, Boozer.
In addition, former Legal Aid assistant director of advocacy Dan Hatcher was awarded the Benjamin L. Cardin Distinguished Service Award. Hatcher is now an assistant professor at the University of Baltimore School of Law.


DPx Gear HEST II Milspec Fixed 3.15" Stonewash Niolox Blade, Black G10 Handles, Cordura Sheath - DPHSX008
RPDPHSX008: HEST II Milspec
The DPx Gear Hostile Environment Survival Tool (HEST) II is a short run, high endversion of the DPX HEST Original. The HEST II is made with German Niolox steel which delivers a harder, more granular cutting edge without the chipping or problems normally associated with very hard tool steels. The scales on the HEST II are thick providing more storage area and a meatier grip
Designed by adventurer Robert Young Pelton and handmade by LionSTEEL in Northern Italy, the HEST II is an upgraded version of the knife that changed the way adventurers think about brutal-use knives.
The 3.15" (80mm) blade of the HEST II is made of German Niolox steel with a 61 Rockwell hardness.
Because the knife is tool steel, and not stainless steel, it is easier to sharpen but may oxidize if not properly cared for. Rust only affects the appearance of the knife and not the performance. Like all DPx Gear knives, we ask that you use a whetstone or diamond sharpener to dress the edge, and NEVER use a motorized grinder.
The blade is 0.187" (4.8mm) thick and features three sizes of wire strippers and a pry notch. There's a hex driver at the hilt and a wire breaker at the base of the blade. We removed a lashing point in the pommel because we found it unnecessary, and we changed the pry bar angle to better fit the size of the knife.
The HEST II has a hollow handle designed for storing survival materials like fire starter or water-purification tablets. The scales are attached with two slotted/Allen screws.
The HEST II Milspec is a take-to-the-fight, low-profile duty knife. The handle is American G10 scales and features a stonewashed German Niolox steel blade with 61 HRC. The Milspec weighs 4.85 oz. and comes with a black Cordura sheath with a sleeve for a sharpening rod or fire starter.
DPx Gear knives are guaranteed against manufacturer defects for the life of the purchaser. DPx Gear reserves the right to repair or replace a knife under warranty at DPx Gear's discretion.
- Overall length: 7.63"
- Blade length: 3.15"
- Blade thickness: 0.185"
- Stonewashed German Niolox steel blade with 61 HRC
- American-made black G10 handle scales
- Cordura sheath
- 304 stainless steel hybrid slotted/Allen screws
- 1/4" hex driver
- Hollow handle
- Unique wire stripper jimping and hard lashing points
- Thumb grip/bottle opener
- Weight: 4.85 oz.
- Made in Maniago, Northern Italy by LionSteel
UPC Code: 857171003176
Formed in a sheet under high pressure by combining fiberglass and an epoxy resin binder. These handles are lightweight and shaped to ensure a solid grip.
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Ontario RAT-3 Utility Knife 3.75" P…
Ontario RAT-7 Survival Knife 7" Pla…
Fallkniven A1 Swedish Survival Knif…
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Gil Hibben Alaskan Survival Knife 6…
Ontario RAT-5 Survival Knife 5.25" …
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Schrade SCHF42 Frontier Fixed 5.12"…
The Original Dog Tag 4 in 1 Surviva…
Schrade SCHF45 Full Tang Bowie Fixe…


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We had more good luck and a very nice day for the hike. There was a lot of delayering on the way up as we climbed the 1,200 feet of ascent. The trail was in excellent condition. There are some good climbs.
After Viewpoint Mike we carried on to the quarry overlook for lunch. We would have stayed longer but a cool breeze came up. The return is all downhill so that went quickly.
A few of us retired to Four Daughters for some Smithick stout.

domain: hobby


Jedrick Wills made it a very merry Christmas for a local Cleveland-area family who needed some good tidings and great joy.
Wills generously gave a woman and her family who lost everything in a tragic house fire a new car and rent for a year. The Browns left tackle also donated $50,000 worth of toys and cash to five needy families.
This isn’t the first time this year Wills has gifted a car. He bought one for his mother after the NFL Draft, where he was Cleveland’s first-round pick.
The moment of Wills’s generosity was captured on camera. It’s worth noting that Wills himself did not post this to any of his own social media outlets.
Calling it Jedrick’s Winter Blast, Browns’ OT Jedrick Wills this week surprised a woman with a new car, paid the rent for a year for a family that lost its home in a house fire, and spread $50,000 worth of toys, gifts and cash to five Cleveland-area families. pic.twitter.com/tdZulT3SrB
— Adam Schefter (@AdamSchefter) December 24, 2020
Well done, Wills!


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Minutes Dec 2016
Minutes of Meeting of the Dunnet & Canisbay Community Council
In Seaview Hotel, John O’Groats
on Monday 12th December 2016 at 7.30 p.m.
Those Present: Eric Green, Chairman
Bill Mowat, Vice Chairman
Chris Hobson, Treasurer
Barbara Hiddleston, Secretary
Cllr. Matthew Reiss
13 Members of the public were in attendance
1. Scottish Natural Heritage (SNH): Proposed Special Protected Areas (pSPA)
1.1 Eric Green welcomed our speaker, Emma Philip, Scottish Natural Heritage (SNH), Coastal & Marine Eco System & Use, and Ian Sargent SNH Operations Officer, Caithness. who accompanied her.
1.2 As agreed at our last meeting held on 31st October 2016, SNH had been invited to give a presentation on the benefits and disadvantages of the proposed SPA to protect particular breeding seabirds around the Pentland Firth. This area is part of the Pentland Firth and Scapa Flow marine draft SPA as seen on the maps below. Those areas highlighted are existing special protection areas.
NB. Maps were taken off the Pentland Firth Proposed Special Protection Area (pSPA) NO. UK9020317 SPA Site Selection Document: Summary of the scientific case for site selection written by SNH & JNCC in which Emma Philip was involved. Source: www.snh.gov.uk/docs/A2013188.pdf
1.3.2 Map 1 shows the extent/area of the proposed Pentland Firth SPA. Map 2 shows the already protected zones as close to Stroma and the Duncansby Head cliff-wall.
1.4.1 Emma began by explaining that this had originally to be a combined ‘Pentland Firth and Scapa Flow’ draft SPA but that these had been separated out as the bird-species were different. In the Pentland Firth it was migrant birds of the three named species that were involved, with them being in the area for the nesting/breeding season. Whereas in Scapa Flow, there was more of an emphasis on resident birds, such as species of ducks, so it was considered best to separate them out.
1.4.2 Emma continued by saying this draft was a shared venture between SNH and the Joint Nature Conservation Committee (JNCC). Those bodies were charged with providing best scientific advice to Marine Scotland and indeed the Scottish Government, which has certain statutory responsibilities for conservation under European Union regulations.
1.4.3 She was here to talk about the Pentland Firth. It is part of a wider programme throughout Scotland with its main aim to protect the feeding grounds of resident and migratory breeding seabirds, particular to each area, from future exploitation/development which could cause decline in their breeding. This can only be done by change in Government Policy which is based on the scientific evidence gathered and found in reports such as this. It is open for public consultation the closing date for this proposed special protection area of the Pentland Firth (and Scapa Flow) is the 17th January 2017.
1.4.4 The birds in question for the Pentland Firth are the Arctic Skua which in Britain only breed in northern Scotland, Common Guillemots, and Arctic Terns. These birds nest during the summer on nearby cliffs, moorlands and islands such as Swona & Muckle Skerry with the feeding grounds for their young and themselves on the rich sea waters around them.
1.5.1 As Emma continued her talk, it became clear that those present whose livelihood depends on the Pentland Firth, such as the creel fishermen/woman, wanted to know what effect this proposed SPA would have on their source of income. They maintained the biggest threat to the seabirds was a natural predator, the Great Skua, and that the number of sand eels, one main source of food, was on the rise and the birds were in good shape. Their knowledge was based on their own practical experience and what they observe each time they go out fishing. Keeping her cool throughout the lengthy heated discussion that followed, Emma continued to explain that the reports were based on scientific evidence. This did not impress those present.
1.5.2 It was strongly emphasised by one member of the audience said he did not believe that the ‘so- called Special Protection Area’ would do anything at all to actually protect the three species of sea- birds cited. Rather, it would have negative consequences for the Human population without having any advantages for the birds - the proposed SPA brings restrictions without any benefits.
1.5.3 If the proposed SPA came into being, these three species would be no better looked after than they are now and deemed that it could not be accepted because of the strength of feeling against it.
1.6.1 Going onto the issue of management as requested by those in attendance, Emma talked about the activities that were seen as potentially a threat to the feeding grounds and those that were not.
Fishing Mobile Gear- mechanical & hydraulic
Fishing- Static Gear
Ports & Harbours
New Development – Renewables – Marine Tidal
Not Potential Threats
Anchorages & Moorings
Fishing – Static Gear – Creels
Infrastructure – cables, pipelines, outfalls
Gas & oil pipelines
Anglers, boating, wildlife tours
Surfing & kayaking
1.6.2 One heading that really caused concern was in Potential Threats: Fishing – Static Gear because in the list of Not Potential Threats was also Fishing – Static Gear, but with Creels as a sub heading. Emma was asked for a guarantee that Creels would not be transferred to the Potential Threat list, which in their judgement she could not give. They reiterated that this was their main source of income in which they were investing both economically and in effort.
1.6.3 The other heading that also caused concern was the New Development – Renewables – Marine Tidal. The MeyGen tidal array in the Inner Sound between Stroma and the Mainland is in the early stages of development – a ‘demonstration array’ – and two marine turbines have been installed during the past month, with two more to follow imminently; the support structures for all four are in place.
1.6.4 Members of the audience said that they looked upon Marine Renewables:Tidal as providing a much-needed source of economic growth for this part of North Caithness. They anticipated that other Crown Estate sub-SPA tidal electricity projects would be developed in the future and one noted that his joinery company had won contracts in building the Ness of Quoys shore station for MeyGen’s developers.
1.6.5 They were very concerned indeed that, by having this listed in the pSPA document as a ‘potential threat’ that this would send out the completely wrong signal to tidal electricity developers and they wondered if the proposed SPA wold prevent or handicap further such developments and stop much-need future economic growth in this area.
1.7 As this lively debate had lasted for an hour and a half, Eric Green brought the discussion to a close and thanked Emma for her presentation. Emma reminded those present that the Consultation date ended at midnight of the 17th January 2017. To make a response online and for more information on the proposals, this information was available on the website www.snh.gov.uk/MarineBirdSPAs. She also agreed to send paper copies of the response form to the Secretary, who will pass them onto the Hotel where they would be readily available. Action Emma
1.8 Eric Green said that as it was also a Government issue, those with concerns should approach our MP Paul Monaghan and MSP Gail Ross as well as responding through the forms. It was noted the Orkney Islands Council had already officially objected to this plan on their proposed SPS and mirrored our viewpoint. Action Eric
1.9 He added that on behalf of the Community, the Dunnet & Canisbay. Community County, would not support this proposed Special Protected Area as it would prove economically disastrous to the area both in terms of economic growth and for the livelihood of the fishermen, and would contact our Members of Parliament. This was supported by the Committee.
1.10 Date of Next Meeting. Due to lack of time it was agreed all business would be carried onto the next meeting to be held in Seaview Hotel, John O’Groats on Monday 23rd January 2017 at 7.30 p.m.


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Air Canada: If you bump passengers, you should compensate them fairly!
This petition made change with 36,883 supporters!
Unlike it's competitor West Jet, Air Canada oversells its flights, bumping travellers and forcing them to wait for hours for the next flight. Worst of all, Air Canada passengers who get bumped from domestic flights are only compensated up to $100. This is insultingly low compared to what airline passengers in the US and EU receive.
In the United States, passengers are compensated up to $1300 depending on the length of the delay and cost of the ticket. In the EU, passengers are compensated up to 600 euros!
The great news is, last week, thanks to a complaint made by passenger advocate Gabor Lukacs, the Canadian Transportation Agency ruled that Air Canada's current $100 compensation is too low, and suggested that Air Canada adopt a model like that in the U.S.
The bad news is there is no guarantee that Air Canada will accept these recommendations. Air Canada has 30 days to respond to the CTA ruling. If we don't speak up they will likely respond by giving reasons why they shouldn't have to pay more than $100.00. But if thousands of us speak up and let Air Canada know we, their customers, demand fair compensation, they'll be forced to act accordingly.
We have until June 26th. Sign my petition and let Air Canada know that if they're going to overbook, bump passengers from flights and make them wait, they had better compensate passengers fairly like airlines do in the US and EU.
For your interest, West Jet, Air Canada's main Canadian competitor, has a policy of NEVER overbooking flights.
***** If you're an Air Canada customer, or if you've been bumped from a flight, please leave a comment explaining what happened to you.*****
Today: Jeremy is counting on you
Jeremy Cooperstock needs your help with “Air Canada: If you bump passengers, you should compensate them fairly!”. Join Jeremy and 36,882 supporters today.


SEHO Auto Loading CNC LATHE
Auto Loading CNC LATHE
A-6+ is the modern machine which is designed and manufactured by SEHO. This AUTO LOADING CNC LATHE equipped with twin spindle and single turret. Twin spindle separate processing two sides in the same machine, like two machines efficiency. The spindle of this machine can also be equipped with power turrent and C axis to satisfy customers in their milling requirement.
Besides, A-6+ also equipped with automatic loading system. The clamping size in the movement of robot arm can be modified according to various workpiece to make the machining process more smoothly. Replace loading unloading by manpower.
A-6+ collocated with FANUC controller, and human-machine interface. This is easy to be used by conversational interface.
- Welcome to SEHO, who many offer the best equipment to suit your requirement!
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It contains the profits of traditional and CNC machines, it could be to reduce the uncertainty problems caused by operator.Read More


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Christmas will obviously look different this year… But Jesus will still be celebrated. We can still bask in the hope that He brings We can still dwell in His love that was so profound that it led Him to leave heaven for us.
And we can still have the kids participate in telling this marvelous story!
My hope this year is to have the kids help me animate the Christmas story. Similar to the videos we use on Sunday, I would like the kids to create the people, angels, scenery, etc. that will show while a voiceover tells the story. It will be simpler than the videos our curriculum provides, but it will be a video they get to create.
If your child(ren) would be interested in helping, please let me know by November 15.
They will then be assigned a person, angel, scenery backdrop, etc. that they will get to create a 2D version of (ie. With construction paper). Further instructions will also be given at that time.
Please let me know by November 15!


Is Consumer Reports Cheating? And Sanity Check on MacBook Pro Battery
Removing the “battery life remaining” to estimate how much power is left on your MacBook Pro, is that a better move that providing a better answer to why the battery life of the new laptop is varying from 3.75hrs to 19.5hrs?
Or is the Consumer Reports cheating on the results when testing the MacBook Pro?
Tune in Mon-Fri for a Tech Sanity Check.
Apple says Consumer Reports MacBook Pro battery testing used flawed methods
More stories and tech updates at:
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Sing a song of first place!
On Thursday 25 May, twelve of our secondary students, along with Mr West and Mr Harrison made their way to the Shoalhaven Entertainment Centre to compete in the High School Choral section of the Eisteddfod and came home with first place.
The group performed two contrasting pieces 'Sing a song of sixpence' and 'When I grow up' which featured at last year's Thanksgiving Night.
Our sections included: Soprano - Jasmine Dickinson, Lisa Burge, Tamsyn McPhail. Alto - Rachel Hill, Charlotte Dickinson, Courtney Nielson. Tenor - Joel Clifton, Joey Ellery, Sam Chittick, Micah Perry. Bass - Sam Ellery, Caleb Mackie.
"Everyone was excited and nervous, especially standing next to Ulladulla High which had around 60 students competing. After a nervous start, we enjoyed ourselves on the stage and sung the best that we could."
While the adjudicator announced first place to NCS, there was much surprise and excitement among all the students. All in all, it was a fantastic day and we all look forward to competing again next year. A special mention goes to Sam Ellery who competed in his final competition with NCS.
The group also performed 'Sing a Song of Sixpence', acapella, for their peers at the Secondary Assembly this week.