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A knifeman, who killed a police officer and wounded one other, was identified to authorities earlier than finishing up his assault.
A knifeman who killed one police officer and wounded one other in Brussels was on a counterterrorism watch checklist, in accordance with Belgium’s authorities.
Federal prosecution Justice of the Peace Eric Van der Sypt mentioned on Friday that the suspect, Yassine M – born in Brussels in 1990, carried out the assault across the metropolis’s Gard du Nord station after night rush hour on Thursday.
One of many law enforcement officials, recognized solely as 29-year-old Thomas M, was stabbed within the throat and died shortly afterwards.
The second 23-year-old officer has been operated on for wounds to the suitable arm and is out of hazard.
The suspect, who had served six years in jail for “frequent legislation offences” between 2013 and 2019, went to a police station earlier on Thursday to specific hatred for them.
Tim De Wolf, the pinnacle of the Brussels prosecutor’s workplace, mentioned the person made “incoherent remarks” on the station.
“He spoke of hatred in opposition to the police and requested to be taken care of psychologically,” De Wolf mentioned.
Yassine M was taken by officers to the psychiatric emergency room of a Brussels hospital, however was not arrested or detained as he didn’t meet the standards for involuntary committal, the officers mentioned.
“He was voluntary,” De Wolf mentioned, explaining that police had left the suspect on the hospital underneath the care of nurses.
“Later, the police contacted the hospital once more to test whether or not the particular person had been saved underneath commentary. It turned out that he had left the hospital,” the Brussels prosecutor’s workplace mentioned.
Yassine was on an inventory drawn up by the Belgian observatory the Coordination Unit for Menace Evaluation (OCAM), which screens “extremism”.
Belgian Prime Minister Alexander De Croo posted a message of condolences to the household and pals of the lifeless officer.
“Our law enforcement officials threat their lives daily to make sure the security of our residents,” he mentioned. “At the moment’s tragedy demonstrates this as soon as once more.”
After the stabbings, Yassine was nearly instantly shot and wounded by one other police officer who had rushed to the scene.
His situation was not disclosed, however authorities mentioned he was nonetheless hospitalised on Friday and unable to be interrogated.
However he’ll now face expenses of “homicide and tried homicide inside a terrorist context”, Van der Sypt mentioned.
Authorities have come underneath fireplace for not arresting the suspect when he threatened the police.
The Brussels prosecutor spokeswoman, Sarah Durant, mentioned procedures stipulate that he needed to be taken by police to a hospital since he had requested for psychological assist.


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BEACON TRANSCRIPT – In a recent comment, HTC has declared that starting today at 3 pm, everyone will be able to buy their very own HTC Vive VR headset. Apart from this stupendous statement, HTC discloses the price for HTC Vive VR. According to HTC, users from the UK can buy the device for 689 pounds.
It will seem that our dreams of engaging in the ultimate experience will come true. In press commentary, HTC stated that starting with the 29th of February, the HTC Vive VR headset can be preordered from HTC’s official website.
Moreover, the tech giant also had the courtesy of disclosing the price for the innovative device. According to HTC’s official page, a potential buyer from the UK can pre-order the Vive VR device for 689 pounds. As for the rest of Europe, anyone can preorder the VR headset for 900 euros.
The company also listed the retails price of the United States. So, if you’re living in the States, you can now preorder the awesome VR reality maker for a measly price of 800 bucks, VAT and transportation taxes not included.
But don’t let the steep price discourage you because HTC has another surprise in store for you. So, apart from the actual VR headset, the box will also feature 3 VR- ready games and hybrid application entitled Vive Phone Services.
Let’s take a closer look at the games included in Vive’s box. The first game is called Tilt Brush, powered by Google. It’s basically an evolved version of paint, but with an added touch of VR magic. Players will be able to paint, draw and sketch almost anything, using only their imagination and the included hand controllers. Your room will become your canvas with this awesome new application.
The second game included in the pack is called Job Simulator. Although the title is not that enticing, the story behind the game is appealing. Apparently the year is 2030 and mankind has been replaced by a race of sentient robots. The player will in control of a robot who goes to great lengths in order to understand the concept of having a job.
And the last game included in the pack is called Fantastic Contraction. Basically, it’s a spin-off after Crazy Machines. The player will stand on a floating island filled with grass and under a blue sky. The whole purpose of the game is to construct an amazing machine and to set it in motion.
The other service offered by HTC, the Vive Phone Services, lets you place calls, receive calls and write text messages using the VR headset paired with your smartphone.
HTC discloses the price for HTC Vive VR headset and also declared that the device will hit all the markets until the 5th of April.

domain: hobby


Blast kills husband of missing Utah woman, 2 boys
Published 4:02 pm, Sunday, February 5, 2012
GRAHAM, Wash. — An explosion at a Washington state home has killed Josh Powell, the husband of a missing Utah woman, plus their two young sons, officials said Sunday.
Powell let the boys in the house, then blocked the social worker from entering. The social worker called her supervisors to report that she could smell gas, and the home exploded.
The children had been living with Susan Powell's parents since Josh Powell's father Steven was arrested on child porn and voyeurism charges last fall. On Wednesday, a judge had denied an attempt by Josh Powell to regain custody, saying she wouldn't consider returning the two boys to their father until he underwent a psycho-sexual evaluation.
Josh Powell was under investigation in the disappearance of his 28-year-old wife from their West Valley City, Utah, home in December 2009. He claimed he had taken the boys on a midnight excursion in freezing temperatures when she vanished.
A lawyer for Josh Powell said Sunday he received a three-word email from his client just minutes before Powell and his two boys died in a house explosion. It said, "I'm sorry, goodbye."
Attorney Jeffrey Bassett tells The Associated Press the email arrived at 12:05 p.m. Sunday, but he didn't see it until two hours later, when others informed him of the blast.
— Associated Press


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Welcome to the official onlline store for AC Creations. Do you need a custom designed tee-shirt and or logo? Maybe you need some promotional flyers for your upcoming event! Or you may be interested in updating those old business cards. Whatever the need, AC Creations is the place for you. We are unlike any other graphic art and design company in the world. We specialize in making our customers look great by providing top quality graphic art and design that is sure to meet the needs of any consumer. Give us a call today and let ACC handle your next project!
We promise to make your process both simple and economical while providing outstanding customer service. ACC will assist you from concept to completion. Whether your project is large or small, we make your job stress free while fulfilling the visual communication needs of your business and or ministry.
AC Creations will work diligently to earn your continued trust. We understand the importance of meeting deadlines and producing work that exemplifies excellent skill and craft. At ACC you can expect high quality standards that ensure that you will receive a project that is the true reflection of your company and or business. Our company makes sure that your business is represented with excellence.
Copyright © 2012 AC Creations
All Images and Pages are Copyright © 2015 Arlise Carson Graphics
These images are not to be used or printed without permission.

domain: artistic


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I absolutely love Lasky's books, and I am (arguably) a grown woman. This one picks up where the last one left off, and young readers who read all of the Guardians books will get a special treat in this one (no spoilers, though - read the book!)
The thing I like best about these books is how intensely character-driven they are. All of the characters - even Faolin, who in the hands of a less capable author might have been idealized or Mary Sue'd to the point of caricature - change over the course of time, and their growth drives the drama, the suspense, and the plot. This is awesome, because it becomes an opportunity for the parents of kids who like the books to talk about the themes of the book (leadership, trust, self-doubt, stereotypes, religion, spirituality, dogma, differences) on whatever level a particular kid is ready to discuss AND relate it to personal growth.
Fast read for anyone over about 8 years old. Good vocabulary words through sixth grade. Subject matter can be experienced on many levels, making the book interesting for all ages. This is a good series for kids who already like the Erin Hunter and Brian Jacques books. One caveat is that the series raises some complicated social and religious questions. You may wish to discuss these issues with your child, especially if your viewpoint differs.

domain: library


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Choose one: Gryfka or Zoniek - and then bounce the ping pong ball until you get to the finish line. In the game you will find different obstacles, whi...
In a few minutes, the soccer game will begin.
Its all up to you to score the winning touchdown.
Tenpin bowling with a twist.
Score points by playing with severed heads.
How many goals can you score
The Home Run Derby is an event customarily held the day before the Major League Baseball All-Star Game. It is a cont...
How many homeruns can you hit?
Homerun rally game
Shoot hoops and try to become a great NBA player in this action filled basketball sports game.
Man your trusty cart and keep your cool while scrambling to keep the club's customers refreshed
Jump! move the jumping board and try to stay on the air as long as possible.
Score as many goals as you can!
Sorry, no description available
Puzzle Soccer celebrates 2010 World Cup! Select one of 16 available teams and play 15 matches to win the World Cup!
This is how the crew of Gilligan's Island entertained themselves during their TV show after their three hour tour
In this Track and Field, Javelin Throw game, you need to throw the javelin as far as you can. The best of your six throws is your score.

domain: game


Thousands of the living strolled among shrines to the dead as Santa Ana celebrated the 10th annual Noche de Altares, or “night of altars,” on Saturday.
Organizers of the event, El Centro Cultural de Mexico and Café Calacas, expected 40,000 people to turn out to view altars, also called ofrendas, set up along Fourth Street. The shrines told the stories of loved ones from a diversity of viewpoints, including those of American-born teens and immigrants who showcased the variety of altar-making styles that flourish each year in Mexico for Day of the Dead.
A free Day of the Dead Family Festival, featuring music, mariachis, and folklórico dancers, takes place at the Bowers Museum, at 2002 N. Main St. in Santa Ana, from noon-3:30 p.m. today. In addition, artist George Newman will display his “Casa de Calaveras” at the nearby Bowers Kidseum. See bowers.org.
- Anaheim police chief asks Donald Trump demonstrators to keep it peaceful today
- Clinton supporters getting ready for her Buena Park visit
- 'Get off the stage!' Some yell at CSUF commencement speaker after she uses Spanish, menti
- Updated: Stabbing, carjacking suspect shot, wounded by Santa Ana police
- O.C., Newport Beach honor John Wayne after Assembly voted against it over his controversi


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Bitstrade Sales Halted by New Jersey Bureau of Securities; Cease and Desist Order Alleges Bitstrade Sold Unregistered Securities in New Jersey
The Bureau of Securities recently issued an emergency cease and desist order that prohibits the online cryptocurrency-related investment entity, Bitstrade, from continuing to sell purportedly unregistered securities in New Jersey, according to an Order from the New Jersey Bureau of Securities under review by attorney Alan Rosca.
Attorney Alan Rosca, of the RoscaLaw LLC firm, is investigating Bitstrade’s alleged sales of unregistered securities.
Investors who believe they may have lost money in activity related to Bitstrade’s alleged sales of unregistered securities are encouraged to contact attorney Alan Rosca with any useful information or for a free, no obligation discussion about their options.
Bitstrade is allegedly not registered to sell securities in New Jersey and is allegedly in violation of New Jersey’s Uniform Securities Law, according to New Jersey Attorney General Gurbir Grewal and the Division of Consumer Affairs.
For example, Bitstrade allegedly offered investors an unregistered security as part of an investment pool which supposedly guaranteed up to a 10 percent return which accrued daily upon investor funds, the New Jersey Bureau of Securities reports.
Bitstrade, which purportedly makes claims to take customers’ Bitcoin and then makes investments in the stock market, had allegedly been offering the equivalent of securities, but had also allegedly not properly registered with the New Jersey government, according to New Jersey regulators.
Bitstrade Allegedly Failed to Disclose Important Material Facts to Prospective Investors Including its Executive Officers, the Company’s Principal Office Address and Purported Financial Condition
Bitstrade also allegedly made violations of the New Jersey Uniform Securities Law by purportedly not disclosing important material facts to prospective investors such as its executive officers, the company’s main office address, and its alleged financial condition, according to the aforementioned Order from the New Jersey Bureau of Securities under review by attorney Alan Rosca.
Bitstrade also allegedly failed to disclose the risks of its investments and how the company invests its investors’ money, according to the New Jersey Bureau.
Finally, said New Jersey order, however, reportedly does not prevent Bitstrade from marketing its products outside of the state, the Order notes.
Securities Lawyers Investigating
The RoscaLaw firm represents investors who lose money as a result of investment-related fraud or misconduct and are currently investigating Bitstrade’s alleged sales of unregistered securities. They take most cases of this type on a contingency fee basis and advance the case costs, and only get paid for their fees and costs out of money they recover for their clients. Attorney Alan Rosca, a securities lawyer and adjunct professor of securities regulation, has represented thousands of victimized investors across the country and around the world in cases ranging from arbitrations to class actions, and has helped recover tens of millions of dollars on behalf of investors.
Investors who believe they lost money as a result of Bitstrade’s alleged sales of unregistered securities may contact attorney Alan Rosca for a free no-obligation evaluation of their recovery options, at 888-998-0530 or via e-mail at email@example.com, or through the contact form on this webpage.

domain: finance


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ORLANDO, Fla./WASHINGTON, (Reuters) – U.S. investigators have questioned the wife of the gunman who killed 49 people at a gay nightclub in Orlando, the FBI said on Wednesday, and a law enforcement source said she could face criminal charges if there is evidence of any wrongdoing.
Omar Mateen’s wife, Noor Salman, knew of his plans for what became the deadliest mass shooting in modern U.S. history, said the law enforcement source, who has been briefed on the matter.
“With respect to the wife, I can tell you that is only one of many interviews that we have done and will continue to do in this investigation,” FBI Special Agent Ron Hopper told a news conference. “I cannot comment on the outcome or the outcome of that investigation.”
CNN, citing law enforcement officials, said a U.S. attorney plans to present evidence to a federal grand jury to determine whether charges will be brought against Salman. She could not be reached for comment.
The first memorial for a victim of the Pulse nightclub massacre, a wake for Javier Jorge Reyes, was held on Wednesday evening at a funeral home near a four-lane highway just south of Orlando. Motorists honked their support of the attendees, many of whom held signs or wore T-shirts reading: “Orlando Strong.”
In Washington, Sunday’s shooting in Florida stirred fresh debate on gun purchases in the United States, as Mateen, who had expressed supported for Islamist extremism, was legally able to buy an assault rifle even though the FBI had investigated him in the past for possible ties to militant groups.
Republican presidential candidate Donald Trump said he would meet with the powerful National Rifle Association lobbying group, which has endorsed him, to discuss limited gun control measures. That marked a break with Republican Party orthodoxy, which typically opposes any restrictions on gun ownership.
The NRA responded that it believed that people listed on terrorism watch lists should face additional reviews before purchasing firearms.
Mateen’s wife was with him when he cased possible targets in the past two months, including the Walt Disney World Resort in April, a shopping complex called Disney Springs and the Pulse nightclub in early June, CNN and NBC reported.
Mateen, a New York-born U.S. citizen of Afghan heritage, was shot dead by police after a three-hour rampage through the nightclub.
Federal investigators have said Mateen, who was 29 and worked as a security guard, was likely self-radicalized and there was no evidence he received any help or instructions from outside groups such as Islamic State.

domain: news


National Confidential Inquiry into Suicide and Homicide by People with Mental Illness
As the UK’s leading research programme in this field, the Inquiry produces a wide-range of national reports, projects and papers – providing health professionals, policymakers, and service managers with the evidence and practical suggestions they need to effectively implement change.
Our research is commissioned by the Healthcare Quality Improvement Partnership (HQIP) on behalf of the NHS England, the Health Department of the Scottish Government, the Welsh Government, DHSSPS Northern Ireland and the Channel Islands to undertake the Mental Health Clinical Outcome Review Programme.
National Confidential Inquiry reports
The reports from our core research programme provide an in-depth analysis of the changing patterns and risk factors behind cases of suicide and homicide by people in contact with mental health services along with cases of sudden unexplained death amongst psychiatric in-patents.
You will find key recommendations for change in our reports for England and Wales, Scotland, Northern Ireland and UK-wide annual reports.
We have also been commissioned to carry out research projects linked to our core research programme. Here, you will find more in-depth knowledge on specific topics such as:
- features of mental health organisations and suicide rates
- in-patient suicide whilst under observation
- suicide by people using primary care services
Our research papers focus on specific issues across a wide range of topics and discuss the clinical implications of our findings.
Research papers and reports can be found in our publications section. They are presented by year of publication.
Our toolkits help health professionals and managers apply the Inquiry’s research findings as they improve service safety and reduce risk.
Here we bring together reports, research papers and projects relevant to important issues in the field today.
Key researchers are always listed in our reports, projects and papers. You can use our people list to get profiles of their research experience, interests and contact details.
'Like' us on Facebook to get our latest research findings


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Key features and details
- Rabbit polyclonal to SAM68
- Suitable for: WB, IP, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-SAM68 antibody
See all SAM68 primary antibodies
DescriptionRabbit polyclonal to SAM68
Tested applicationsSuitable for: WB, IP, IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Rabbit, Guinea pig, Chimpanzee, Rhesus monkey, Gorilla, Orangutan
Synthetic peptide corresponding to a region between residue 1 and 50 of Human SAM68 (NP_006550.1).
- Whole cell lysate from HeLa cells.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferPreservative: 0.09% Sodium azide
Constituents: 0.1% BSA, Tris buffered saline
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab86239 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/2000 - 1/10000. Predicted molecular weight: 49 kDa.|
|IP||Use at 2-5 µg/mg of lysate.|
|IHC-P||1/500 - 1/2000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
FunctionRecruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain-containing proteins. Role in G2-M progression in the cell cycle. Represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. Also acts as a putative regulator of mRNA stability and/or translation rates and mediates mRNA nuclear export.
Isoform 3, which is expressed in growth-arrested cells only, inhibits S phase.
Tissue specificityUbiquitously expressed in all tissue examined. Isoform 1 is expressed at lower levels in brain, skeletal muscle, and liver whereas isoform 3 is intensified in skeletal muscle and in liver.
Sequence similaritiesBelongs to the KHDRBS family.
Contains 1 KH domain.
Developmental stageIsoform 3 is only expressed in growth-arrested cells.
DomainThe KH domain is required for binding to RNA.
The Pro-rich domains are flanked by Arg/Gly-rich motifs which can be asymmetric dimethylated on arginine residues to give the DMA/Gly-rich regions. Selective methylation on these motifs can modulate protein-protein interactions.
modificationsTyrosine phosphorylated by several non-receptor tyrosine kinases, for example LCK, FYN and JAK3. Negatively correlates with ability to bind RNA but required for many interactions with proteins.
Acetylated. Positively correlates with ability to bind RNA.
Arginine methylation is required for nuclear localization. Also can affect interaction with other proteins. Inhibits interaction with Src-like SH3 domains, but not interaction with WW domains of WBP4/FBP21 AND FNBP4/FBP30.
Arg-291, Arg-331 and Arg-346 are found to be also dimethylated, probably to asymmetric dimethylarginine.
Cellular localizationNucleus. Membrane.
- Information by UniProt
- FLJ34027 antibody
- GAP associated tyrosine phosphoprotein p62 antibody
- GAP-associated tyrosine phosphoprotein p62 antibody
All lanes : Anti-SAM68 antibody (ab86239) at 0.04 µg/ml
Lane 1 : Whole cell lysate from HeLa cells at 50 µg
Lane 2 : Whole cell lysate from HeLa cells at 15 µg
Lane 3 : Whole cell lysate from HeLa cells at 5 µg
Developed using the ECL technique.
Predicted band size: 49 kDa
Observed band size: 60 kDa why is the actual band size different from the predicted?
Additional bands at: 250 kDa. We are unsure as to the identity of these extra bands.
Exposure time: 3 seconds
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human prostate carcinoma tissue labelling SAM68 with ab86239 at 1/1000 (0.2µg/ml). Detection: DAB.
Detection of SAM68 in Immunoprecipitates of Whole cell lysate from HeLa cells (1 mg for IP, 20% of IP loaded) using ab86239 at 3 µg/mg lysate for IP (Lane 1) and at 1 µg/ml for subsequent Western blot detection. Lane 2 represents control IgG IP. Detection: Chemiluminescence with an exposure time of 1 second.
ab86239 has been referenced in 2 publications.
- Puckette M et al. Foot-and-Mouth Disease (FMD) Virus 3C Protease Mutant L127P: Implications for FMD Vaccine Development. J Virol 91:N/A (2017). PubMed: 28878081
- Rao M et al. Isobaric tags for relative and absolute quantification-based proteomic analysis of testis biopsies in rhesus monkeys treated with transient scrotal hyperthermia. Oncotarget 8:85909-85925 (2017). PubMed: 29156766

domain: medical


Published on : Mar 20, 2014
Researchers at the university of Texas have come up with a revolutionary windmill with a generator that can charge mobile devices very easily. What’s more interesting is the size of the device-so miniscule that about 10 of such devices can easily fit in a space needed to fit a single grain of rice. Technically speaking, the device is so small that it measures about 1.8 mm at its widest point.
The device incorporates the use of grippers, pop-up switches, inductors and gears- all as tiny as a fraction of the diameter of a human hair.
The design credits to two fellow researchers- J.-C. Chiao, an electronic engineering professor and Smitha Rao, a research associate at the Texas University.
The tiny size of the device can allow hundreds of them to be mounted on a cell phone sleeve to recharge the phone. Once the user puts the sleeve on the phone, it simply has to be waved in air or be kept in a windy place. Once in contact with wind, the pressure of wind would propel and turn the tiny blades of the device, allowing the micro generator in it to produce electricity.
The design of the device takes inspiration from origami concepts, blended with the conventional lay-out of wafer-scale semiconductor devices.
The nickel alloy used in the device is flexible and the design is such that it requires minimal efforts for functioning, combined with each other, these two points have helped in making the device more effective.
The devices were successfully tested in Chiao\'s lab in September 2013 and it was found that even under strong artificial winds, the device suffered no fractures in the material and worked smoothly.
The device can be made in bulk using batch processes and so, the price for fabricating a single unit of it will be same as that for fabricating hundreds and thousands of it.
Because of the small power, flat panels with thousands of such devices can be installed in residential areas and allow for the production of cheaper, safer and good amount of electricity that can be used for many purposes.


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Description & Details
Whales symbolize courage in love, and butterflies are the embodiment of constancy and happiness in love.As a whale, I wander all over the world just to pursue you; I also wish to turn into a butterfly and dance only for you.
• Material: Solid 925 Sterling Silver ∙ Cubic Zirconia
• Finish: Hypoallergenic ∙ Gold Plating
• Dimensions: US size adjustable
• All our work is custom made by hand with love


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- Post on Fri, Nov, 18, 2016
O R D E R
Shri Anil Divan, learned Senior Counsel appearing for Jagran Pakashan Limited has raised a preliminary objection to a consideration of the legal submissions formulated by contending that the same raises new questions which travel beyond the ambit of the order passed by this Court in respect of which disobedience has been alleged. Shri Divan has further submitted that such questions cannot be adjudicated in exercise of contempt jurisdiction. Page No.11 of 12On the other hand, Shri Gopal Subramanium, Shri Salman Khurshid, Shri Vijay Hansaria, learned Senior
Counsels appearing for the other newspapers establishments have submitted that they require further time to go through the legal submissions formulated in the case by Shri Colin Gonsalves, learned Senior Counsel and seek instructions in the matter. Learned counsels pray for four weeks' time. In the aforesaid circumstances we adjourn the hearing of these cases to 10th January, 2017. On the said date, the preliminary objection raised by Shri Anil Divan, learned Senior Counsel will also be considered. Additional affidavit(s)/document(s), if any, may be
filed in the meantime.
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Charge-off reports and records in collections within 5 years, when they was not paid back, would now count against candidates for PLUS loans.
The alteration had been made quietly – the division didnвЂ™t convene a rule-making panel or issue a page to universities describing it – however the effect had been dramatic, Kantrowitz stated. Some creditors will place records in collections in case a re payment is just 30 days later. Moms and dads that has formerly been entitled to the loans discovered that they had now been refused.
Denials for PLUS loans jumped following the brand brand brand new requirement took effect, midway through the 2011-12 educational 12 months. In accordance with initial Education Department information, 38 per cent of candidates when it comes approved-cash.com/ to loans had been denied – ten percent a lot more than within the past year. Read More


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I loved the sound of this book and was so happy to get chosen to take part in the FFBC blog tour for it. Be sure to read down to find out all about this amazing book, my review and the chance to win a copy US/Can residents only.
Nandi Taylor is a Canadian writer of Caribbean descent based in Toronto. She’s a two-time Watty award winner, and her Wattpad story Given has garnered over one million reads and earned the 2018 Worldbuilders Watty award.Nandi grew up devouring sci-fi and fantasy novels, and from a young age wrote books of her own. Her books are an expression of what she always
wanted more of growing up—diverse protagonists in speculative settings. Common themes she writes about are growth, courage, and finding one’s place in the world.Her debut novel Given will be published by Wattpad Books in January 2020.
by Nandi Taylor
Publisher: Wattpad Books
Release Date: January 21st 2020
A subversive fantasy-romance steeped in West-African and Caribbean traditions.
Yenni has never been this far from home. With only her wits, her strength and her sacred runelore, the fierce Yirba warrior princess is alone in the Empire of Cresh. It’s a land filled with strange magics and even stranger people—many of whom mistrust anyone who’s different. But Yenni will prove herself, and find a cure for her father’s wasting illness. She will not fail.
No one warned her about the dragons. Especially not about him.
Yes, there is something powerful and compelling about the violet-black dragon known as Weysh. In human form he’s muscular, beautiful—and completely infuriating. What kind of arrogant creature claims a stranger as his Given; as his destined mate? Yenni is no man’s—or dragon’s—plaything. But other magics must be at work here, because Weysh might just be her best hope at finding the answers she seeks.
Only now Yenni can’t tell if she’s fighting her attraction to a dragon…or fighting fate itself.
Yenni Ajani, the chieftains daughter, has never travelled off her Island. But with her father becoming sick and their healers having no idea of the cause Yenni knows she has to be strong and travel alone to Cresh to learn all she can about the disease plaguing her father. But nobody warned her that in Cresh Dragons still exist, and certainly nobody warned her about the concept of a Given. When Weysh her supposed ‘Given’ practically claims her it takes all of Yenni’s strength not to kill him on the spot. However, as they get to know each other Yenni realises that Weysh might be her best hope to finding answers about the disease. But with them spending time together feelings begin to develop and Yenni must decide between what’s best for her people and what her heart wants.
Yenni Ajani is a headstrong character, not afraid to speak her mind and back on the Moonrise Isle’s people listen. The only problem is the Chreshans see the islanders as ‘less’ and almost archaic in their ways. Seeing her overcome these trials and tribulations made for an intriguing read, and I loved that she never faltered in her beliefs. She is though, a young girl, and with that comes all the romance, hurt feelings and the feeling of not really belonging. I really enjoyed following her journey. Weysh was a character I truly disliked at first, and though he grew on me, I still wasn’t his biggest fan at the end. His belief that because Yenni Ajani is his Given she should drop everything to become his wife and sire his one Dragon child made him come across as entitled and sexist. Through talking to his friends and Yenni he comes to see the error of his ways, though there are some definite tantrums along the way.
I found the premise for this book slightly deceiving. Does Yenni travel to Cresh? Yes. Does she meet Weysh, her Given? Yes. However, there is no mention of the magic school in which the character spend the majority of the book studying in. I enjoyed this part of the book ( always love a good magic school) and liked the authors descriptions of the classes and different types of magic they learn. I found the magic system quite intriguing. With a rather simplistic design, the magic on Cresh comes from spoken words i.e, “source drawn rain dry up and cease’ would remove water from a person’s being and space around them. The magic on the Moonrise isles is something different. Yenni’s people use Runes to control their magic. They sing wordless songs while applying a special paste to their skin and use these to give them speed, less pain etc. I liked seeing the clash between the two types of magic and Yenni’s struggle to learn a whole new concept was reminiscent to people having to learn a completely new language.
We see a few subjects being addressed in different ways. Racism with Yenni being seen as quaint and archaic for using Rune’s instead of Creshan magic. Her people are seen as lesser and she struggles through a good chunk of the book with overcoming this ideal. There are also hints of Colonisation with the Creshan people controlling the empire, including the Islands where Yenni lives and forcing their ideals and magic style onto others. The author uses her West African and Caribbean culture to show the differences between the people, you could read it in the different dialects, and in how they dressed/acted.
The romance in this book was a bit too quick for me. I felt that Yenni went from having absolutely no feelings towards Weysh, except for maybe wanting to push him off a cliff, to admitting to him and herself her romantic feelings. Whether this was to do with them being ‘Given’ (she had no choice in the matter etc) I don’t know but it felt like she did an almost 360 in the span of a few pages.
Overall I enjoyed this book. Would I run out to buy the sequel if there is one, probably not. But I am intrigued to see where the story goes. 3.5*
Thanks to the lovely publishers I am able to offer one copy of this book to US/Can residents only. Simply complete all the the mandatory entries, and comment with what kind of magic you would love to learn ( So I know you’ve entered)! Giveaway is open until 31st January.a Rafflecopter giveaway </script
Every blog will be running their own giveaway & the more you enter the better chance you have so be sure to check the tour schedule above and check out all the other amazing posts!
-Open only to US/CAN Residents.
– Must be 13 or older to enter
– Giveaway starts XXXX until XXXX.
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-All entries from “giveaway” accounts will be disqualified.
– Your personal information won’t be used or be seen unless you’re the winner of the giveaway. We won’t sell it nor use it in a bad way.
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– One person cannot win more than one prize in a same giveaway. See The FFBC Tour Guidelines on their website for more information.

domain: literature


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The kitchen is the most dealt zone in a house; spilling, stepping and running, your kitchen takes everything. In any case, with normal support and by utilizing the correct wood and finish you can have solid wooden ground surface in your kitchen.
Here are a couple of things that you should consider before getting your kitchen wooden amazed.
The best types of wood for Kitchen
When flooring your kitchen, it is prudent to consistently for the hardest wood. Oak and debris are probably the most grounded local wood species utilized really taking shape of wooden floors. The best bit of leeway of utilizing these species is that their excellent and substantial graining and sensitive surface make your kitchen floor wonderful as well as helps disguise the little scratches and gouges that will undoubtedly happen after some time.
There are other more grounded wood species accessible in the market like Jatoba and Santos Mahogany, yet the fundamental weakness of utilizing them is that they will in general change shading and obscure after some time. Additionally, they are truly helpless to moistness changes.
The best wood completes for Kitchen
Wooden floors in the kitchen need to have a defensive covering to forestall the retention of dampness and stains. Albeit the vast majority of the wood floor completes accessible, today are reasonable for kitchens, utilizing a water-based clear completion is frequently suggested in light of the fact that they save the wood’s shading and can be effectively re-covered. The best water-based completion is a production line applied, acrylic-impregnated finish that diffuses through the wood rather than simply remaining on a superficial level. Despite the fact that acrylic covered floors are increasingly costly, they are more grounded and require less upkeep. Likewise utilizing glossy silk sheen finish helps mask earth.
Polyurethane polish completions are extremely solid and tough. They are all that anyone could need for any home inside. Be that as it may, in the event that there is an excess of harm, at that point portions of the floor or at times the whole segment should be supplanted. The parts close to the sink, the oven, and the cooler are generally defenseless against harms from drops and spills. You can utilize carpets to make sure about these parts.
UV-relieved oil completes are not as solid as enamels, yet the advantage of an oil finish is that the harmed regions can be fixed or reestablished rapidly. Spot fixes can be made by utilizing sanding paper. An oil-completed hardwood floor is a reasonable choice for a kitchen where the spills are tidied up right away.
Coordinating kitchen cupboards with wooden floors
The kitchen looks engaging when the floor and the cupboards have differentiating looks. For instance, in the event that you pick a dull floor, you may need cupboards painted in a light shading or produced using a light wood.
Keeping up Hardwood Floors in a Kitchen
• As referenced kitchen floors will endure water spillage and recoloring so it is important that these wooden floors are given several coatings of the fixing operator to forestall dampness entrance.
• If anything spills, make a point to wipe it up quickly, and never let water remain on the wooden surface for long.
• Make sure that you don’t scour or utilize any solid synthetics for cleaning. Use items particularly prescribed for wooden floors to reestablish the first sparkle of your floor.
• It will likewise be basic to clear or vacuum the floors oftentimes, to keep them liberated from coarseness and grime that can scratch the wood and erode the completion.
• If the floors get harmed, you can get them resurfaced. This procedure includes sanding the surface and re-applying the defensive layers.
Preferences of Wood Flooring in kitchen:
• Wood is a warm material that brings indispensable vitality into your Kitchen. What’s more, on the off chance that you are utilizing wooden deck for all your different spaces, at that point utilizing the equivalent for your kitchen guarantees uniformity in your style. This is particularly noticeable in homes with open kitchens where the kitchen is by all accounts an expansion of the family room.
• Hardwood floor is enduring, and it tends to ages smoothly.
• Hardwood floors are condition cordial and are the most advantageous floors which make a spotless situation.
• The kitchen is one zone where at least one individuals will invest a great deal of energy remaining as they cook. What’s more, that is the reason the solace of the floor is basic. Wooden deck offers a milder and increasingly agreeable surface to remain on. Studies have demonstrated that wooden floors are useful for the spine and the joints of your body!
Hindrances of Wood Flooring:
• The wooden floors need customary finishing each 3-4 years to keep up its completion in high rush hour gridlock zones, for example, the kitchen. Furthermore, the expense of cleaning is high.
• Wooden ground surface will be harmed in case of any water flood or seepage which is visit in kitchens. Holes will be a standard concern when you choose to introduce wood in your kitchen. The main way deal with this risk is to ensure that all apparatuses are looked after appropriately, and all the channels are strong and liberated from any holes.

domain: design


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The first such compound was prepared by Jonas et al in 1997 (DOI). Reaction of titanocene dichloride with the dilithium salt of pentalene forms Ti(eta8-C8H6)(Cp) with titanium simultaneously coordinating to 8 positions on the pentalene frame and 5 on the Cp frame. The related Ti(Pn)(Cp)Cl is obtained by further reaction with dichloromethane as an 18 VE compound. Interestingly, although the pentalenyl ligands are aromatic, they are not planar but have a fold angle in the range of 30 - 40°.
When the bimetallic orientation is trans rather than cis it is in principle possible to create (M(Pn))npolymers which are of potential interest as molecular wires. One of the first efforts to be recorded , a (*Cp)2PnFe2 trimer, is one by Manriquez et al. in 1988 (DOI).
Most recently the double metallocene family was extended by O'Hare et al. with a range of *Pn2M2 compounds with M vanadium through nickel and *Pn the pentalene version of pentamethylcyclopentadiene (DOI). Intriguingly the iron sandwich resists synthesis with the pentalene ligands instead opting for dimerization.


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Chilean New Song (la Nueva Canción chilena) entranced and uplifted a country that struggled for social change during the turbulent 1960s and early 1970s, until the 1973 coup that overthrew democratic socialist president Salvador Allende. This powerful musical style—with its poetic lyrics and haunting blend of traditional indigenous wind and stringed instruments—was born of and expressed the aspirations of rising classes. It promised a socially just future as it forged social bonding.
In Chilean New Song, J. Patrice McSherry deftly combines a political-historical view of Chile with a narrative of its cultural development. She examines the democratizing power of this music and, through interviews with key protagonists, the social roles of politically committed artists who participated in a movement for change. McSherry explores the impact of Chilean New Song and the way this artistic/cultural phenomenon related to contemporary politics to capture the passion, pain, and hope of millions of Chileans.

domain: sociology


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It's been confirmed that a case of a tree fungus which kills ash trees has been found in woodland in Dorset. The new case of Ash Dieback near Dorchester follows the discovery of the disease in Devon last month.
More top news
A couple who lost an unborn baby to complications from twin to twin transfusion syndrome have raised money for research into the condition.
Dorset has a new migrant population - barrel jellyfish are washing up in their dozens on its shores.
The family of one of Britain's oldest poppy-sellers say charities which bombarded her with donation requests were not to blame for her death


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Enugu State lawmakers under the aegis of the Forum of 260 Ward Councillors have mourned their late colleague, Mr Sylvester Ofunwa.
Ofunwa, the Councillor representing Eha-Ulo Ward in Nsukka Local Government Area, was murdered by suspected hoodlums in his hometown in the Eha-Alumona community on Sunday, July 16.
The Coordinator of the Forum, Chief Nnamdi Odo told journalists after the prayers and candlelight procession of hundreds of councilors in Enugu,, that the councilors gathered to mourn “the gruesome killing of an honorable councilor last week”.
According to Odo, our departed colleague, Ofunwa, until his death, was a great crusader for justice and community development.
“The 260 ward Councillors in Enugu State also used this mourning gathering to pray for His Excellency, Governor Peter Mbah, and for the success of his administration especially in the area of security.
“We commend the state government’s efforts in ending the menace of sit-at-home in the state.
“We pledge our support in mobilising our wards to key into this fight, aimed at restoring the economy of our state,” he said.
Odo, who is also the spokesman of the Forum, said that the councillors were also begging for improved welfare for councillors especially due to the current economic hardship.
“The monthly take home and allowances of Councillors do not reflect the present situation of the country. The burden of the political ward falls on us with our meager salary,” he said.
The coordinator said that the councillors commend the state’s commissioner of police and all the security agencies in the state for their speedy response in investigating the murder case of Ofunwa.
He said, “The Forum equally implores them to speedy action to bring the perpetrators to book.
“Finally, we call on the Commissioner of Police to beef up security in our various political wards in the state.”


A Secret Weapon For best appliance toolsHVAC breakdowns can impact not merely your comfort but will also your overall health. Once your furnace is not Performing, or your air conditioner is just not cooling, Serious temperatures can be a danger. Rely on Sears Residence Companies for heating and air conditioning repairs that restores ease and comfort and security to your property.
The yellow juicers are created for lemons but get the job done for lesser limes, much too; You may also get orange-coloured versions that are made for—you guessed it—oranges.
This is actually the variety of occupation that should be left towards the pros. For many other repairs, a simple list of hand tools, and a great digital multimeter is all you might want to do most major appliance repairs.
Push Alt/ Possibility and click the tool group. This action cycles through every one of the tools current inside the tool team.
This is a robust mixer, and much like the Ankarsum, is usually a bottom motor design and style. It’s 800 watt mixer motor is made in Germany, it's got four speeds, and there weren’t any volume of grievances all over it ever burning out.
This web site is delivered for facts functions only and is not warranted for being error-cost-free, neither is it subject to almost every other warranties.
No matter if you might be commencing a brand-new kitchen or your appliance cupboard is bursting within the seams, these tools should have a place in your home.
There's actually no substitute for steaming, as well, and once you have a steamer, a whole technique for cooking opens alone your decision, without having additional products. Get steamers that suit over your widest pot to present on your own as much versatility as you possibly can.
We hope you found this details helpful. We much like the four stand mixers on this site for weighty dough baking and cooking.
The meter calculates the quantity of electrons that were available to head out, and compares that to the number of electrons that came again. It shows the final results of that calculation over the electronic display, in the form of a device of evaluate called ohms. And do not forget to get alligator clips for your personal meter check qualified prospects. Alligator clips slip to the finishes with the exam potential customers making use of friction and assist you to hook up the meter securely to test for electrical energy, or resistance.
Hobart is definitely the identify you see most frequently at the back of industrial bakeries and dining places. If you’re a significant at-household Cook dinner and large batch baker, that is a strong device crafted to past decades.
Locating the right Software set for just a specialised job is often tricky. Tackle your future improvement challenge confidently by using tools from leading brand names like Dremel, BLACK & DECKER, Kobalt and Bostitch.
Seems it could conserve your daily life when you drop odd sized screws down into challenging to succeed in spots on the appliance. Expend the three bucks, and conserve your self several hours of dumb retrieval time.
I presently had this reasonably priced merchandise in my toolbox. You will use this continuously to check the existence of AC present-day at diverse spots within the appliance.


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Lexi’s step-by-step custom logo design process
Process is everything when it comes to bridging the gap between client and creative. Professional creatives have refined-over-time procedural approaches to every service they offer. The more clarity we can gain up front, the better the end product will be (and the more enjoyable the experience for all parties involved).
Take a peek at the refined, fun, and results-focused process I’ve developed for custom logo design, after having had designed dozens of custom logos for varying clients over the years. If you’re considering hiring a custom logo designer, I’d love the opportunity to walk through this process with you!
Step 1: You fill out my Logo Design Discovery located here.
Tip: Take your time with this. Feel into it. Take it seriously. This is my first impression of what you’re looking for and the more detail you can provide here, the deeper my initial understanding of your vision will be.
Step 2: I create a mood board for your logo/brand on Pinterest.
Tip: If you don’t already have an account on Pinterest, go ahead and create one. I’ll ask you to leave a comment on each pin I add to your mood board. I’ll want to hear your reactions — positive and negative — as this will help us become visually aligned before I get started on the first pass of logo comps. I’ll add photos, fonts, color palettes, and other graphics to this mood board. I’ll probably include some that I know you won’t like because it is equally helpful for me to hear what won’t work for you as it is to hear what will work for you. Again, take your time with this as it helps me intuitively tap into your project.
Step 3: You provide your reactions to each pin on the Pinterest mood board.
Tip: Log in with your Pinterest account and comment on every pin on the mood board. What do you like and why? What don’t you like and why? Do you like part of a pin, but not the whole thing? I want to hear all of your reactions.
Step 4: I create the first round — 3 unique logo comps.
FYI: I’ll show you each unique logo comp mocked up with a few different treatments. You’ll see how each comp might look on a light background, a dark background, and possibly on a business card. I want you to get a feel for how each direction could work in a variety of different settings. I’ll denote each comp with “A," "B," and "C” so you know what’s what. In the end, you’ll want a logo that’s flexible enough to work printed in a magazine, animated on your website, or possibly converted to grayscale. That’s why I like to show each comp mocked up with different treatments.
Step 5: You provide honest, clear feedback.
Tip: Read my blog post How to give effective design feedback here. It’s important that you are clear on what you want and that you can verbalize that to me so we can keep the process moving forward in a constructive manner.
Step 6: I incorporate your feedback into a second round of logos.
FYI: Here, we should be focused on winnowing down to 1 or 2 of the directions from the first round. I make tweaks and refinements based on your feedback and deliver a revised second round.
Step 7: We repeat steps 5 and 6 a couple more times if needed.
FYI: Included in my base cost is up to 3 rounds of revisions. I want you to be 100% happy so I am willing to go above and beyond. However, if we are well exceeding 3 rounds, especially if it’s because you’ve changed your mind and the feedback or creative direction you provided at earlier points in the process has changed, I will bill hourly.
Step 8: You select your dream logo!
Tip: Pop the bubbly! You have now decided on the look and feel for your brand. Your new logo will empower you to build visual recognition for your business across your website, in your advertising, in your email marketing, and more. I hope to be part of the process along the way.
Step 9: I send over a .zip with a plethora of logo assets and a mini graphics standards manual.
Tip: Download the fonts from the graphics standards manual and start incorporating them into your documents. Forward along the graphics standards manual any time you have something printed with your logo in it — the printer will appreciate being able to match your brand colors precisely. As a general rule of thumb, use files ending with .PDF for print and files ending with .PNG for web. Files ending with .AI are master files and can only be opened and manipulated by professional designers who have the industry standard logo design software, Adobe Illustrator.
While creative professionals are often viewed as artists, we don’t only see ourselves that way. Yes, we utilize artistic skill and vision to bring your dreams to life, but we also know we are being hired to create an end deliverable for you, the client. This custom logo design process helps to ensure the skill from the designer (me!) and the vision from the client (you!) meet in harmony, resulting in a strong, memorable logo for your business!


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Petrobras corruption scandal has developed new dimensions as Fernando Soares, who was indicated in bribery charges, called for his defense in court executives from South Korean giant Samsung Heavy Industries, as well as witnesses from Japan, the Netherlands and Cayman Islands.
Last Wednesday, during the hearing in the federal court in Curitiba, Soares was appointed as the middlemen, who arranged the payments between former Petrobras executives, among which is the former director Nestor Cervero and Korean shipbuilding firm. The prosecution just came out with the information about paid by the Korean company bribes and money laundering. Though the accusations, none of the Samsung Heavy Industries representatives have been charged, yet.
In a media release, Edson Ribeiro, the lawyer of Nestor Cervero, claimed the called witnesses might prove that there were no irregularly deals between Prtrobras management and the Korean shipbuilder, during the period between 2006 and 2007.
The Petrobras scandal is on its way to get even bigger as the Suprime court required the opening of investigations into anothe 54 people, most of whom are politicians.
The current president of the country, Ms. Dilma Rousseff, was a chairwoman of the board of directors of Petrobras from 2003 to 2010, when is supposed that much of the bribes happened. Under a vow the president denied to have any knowledge of what happened during that time, though statistics show every third of four Brazilians does not believe her. This makes her position very insecure in time when the country should fight against drought, weak economy, high unemployment, lower commodities prices. Due to the scandal, the country has already lost a few investment projects.
Therefore, Petrobras case is believed to be Brazilian largest ever corruption scandal, involving the names of politics the investigation may last for years before the truth gets revealed.
Related news: Rolls-Royce dragged into Petrobras bribery scandal

domain: law


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Are you ready to help?
Kennel Assistants Needed!
We are currently looking for people to join our team of Kennel Assistants. Our Kennel Assistants take care of our short term visiting dogs. The visiting dogs are treated like our own pups during their stay.
The kennel assistant duties can include:
- Play with the dogs and taking them out to do their business.
- Tidy up the kennel area, making sure it always looks great, a place that shows our pride.
- Ensure each dog has clean bedding and fresh water
- Wash breakfast and/or dinner bowls, and set up for the next meal.
- Checking in/out visiting dogs.
- Some ‘poop’ scooping.
We are hoping to add three Kennel Assistants who can come once a week for an evening shift. The shift may take a couple of hours depending on the number of short term visitors.
The evening shift is 6pm to 8pm. We are looking to fill the following Kennel Assistant shifts.
Every other Every Thursday, Every Friday and Every other Saturday.
Experience with dogs is a MUST and the volunteer should be confident and eager to handle dogs, big or small. You must be 18 or older.
Please fill out the form to be contacted by the Volunteer Coordinator

domain: pet


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Rickshaw has won the creative duties of Canada-based Faces Cosmetics following a multi agency pitch process. The agency has been mandated to create a new identity for the brand in India. Though the brand was launched a couple of years back in India, this is the first time they have hired an agency in India.
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Moves from Hansa Cequity
New global initiative to ensure more equitable share of investment in trusted news sources, and minority-owned and operated media
New title will be 'source of truth' for fast-growing digital sector


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Happy Labour Day Weekend! Use the code LABOURDAY22 to enjoy 20% off your purchase!
"Refresh your soul and allow yourself to see beauty in all you behold".
A uniquely beautiful, free form pendant necklace that sits perfectly along the collar bone. This handmade necklace is 18K gold plated.
Moss Agate: Prosperity, Restoration, Healing
Length: 44 cm


text:
Container for gardening made of polypropylene geotextile of good quality.
Container for gardening made of polypropylene geotextile of good quality. These fibers are resistant to biological degradation environments commonly found in soil.
Designed to promote aeration of the root zone.
When roots reach the wall of the pot, the air is responsible for pruning.
Avoid circular root growth.
Creates an air barrier to isolate the root during the cold season.
This same barrier prevents overheating of the root zone during the hot months.
Easy and economical to transport.
They presented conveniently folded to occupy minimum space.

domain: agronomy


text:
Here's the thing: I like my privacy in the bathroom.
I teach my son about privacy and remind him to close the door when he is in the bathroom. My husband and I keep the bathroom door closed on each other, keeping the mystery alive in our marriage.
I am all for family bathrooms in public places. I applaud the businesses that have put those facilities in to make life a little easier for parents having to take their opposite-gendered child into the restroom with them. I love no longer having to take my son into the women's restroom with me when the two of us are out running errands together.
But, as a general rule, I don't want to have gender-neutral public bathrooms be the norm.
Once upon a time, I worked for a privately held company that was mostly a boys club. All the bathrooms were single-stalls and gender neutral. And the few women that did work at the company were generally upset at the state of those bathrooms and sharing them across both genders. (The men didn't seem to care either way.)
I am not saying that one gender is cleaner or that bathroom use is different or anything like that. I am saying that the bathroom is the last place in the U.S. that is still segregated by gender. And I am OK with that. I am OK that in the moment where I feel most vulnerable and exposed and am trying to take care of my body's needs, I don't have to see the opposite gender.
Would you be fine with gender-neutral public bathrooms being the norm? Tell me your thoughts in the comments.


Sunday, July 06, 2008
Left: Dave Springford - SOSA president, World Contest pilot, chef.
The Globe and Mail, read across Canada, is one of the country's top news organizations. Reporter and pilot Peter Cheney profiles SOSA pilot Dave Springford prior to the World Glding Championships. The piece contains a great video. Read and see the videos right here.


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Ebony loves to talk about reading and writing! She is available for school and library visits, conferences, and writing workshops. Let’s connect! Here’s where you can find me:
News & Media
News & Media
School Visit Reviews
Thank you for sharing your time with us – the students really enjoyed it! This is also a first in our district that we’ve had someone Skype/video chat with students in the classroom, and for it to be about something that directly relates to instruction is awesome. Thanks so much!
-Joseph J., W.R. Coile Middle School, Athens, GA
After reading your book, I was blown away for many reasons. I wish somebody would have sat down with me when I was younger and now I have an opportunity of doing so. I wanted to thank you for sharing your passion with us
-Carmen D. Cleveland, OH
Thank you so much for an excellent book. I intend to buy more copies and “push” it to all the students here at Southwest High School. I look forward to reading more of your work
-David B. El Centro, CA
Thank you for coming in to speak with our BookTalk kids. It was an inspiring event for all of us. All the best to you!
-Sarah W., PS199, New York, NY
Many thanks for sharing your new book with our group. It was a big hit with them!
-Vicki, PS199, New York, NY


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Plans for apartments on vacant plot of land in Fulwood, Preston
Plans have been submitted for a block of 14 apartments and a detached house on a vacant plot of land in Garstang Road, Fulwood.
According to documents lodged with Preston Council, the development will have “a traditional theme with a modern twist,” with the design based largely on properties nearby.
The apartments will all be two-bedroomed and car parking for 32 vehicles will be provided.
In October 2015 the same site was granted planning permission for nine apartments and one detached home. And in August 2017 plans for six detached houses were also passed.


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Versatile actor Rekha will be seen in a special appearance in “Yamla Pagla Deewana Phir Se”, starring Dharmendra, Bobby Deol and Sunny Deol.
“Yamla Pagla Deewana Phir Se” is directed by Navaniat Singh and produced by Vijayta Films. Salman khan, Sonakshi Sinha and Shatrughan Sinha will also be making a guest appearance along with Rekha. According to some reports, Rekha will be seen shaking a leg with Dharmendra to a medley of their hit track ‘Rafta Rafta Dekho Aankh Meri Ladi Hai’ from the film “Kahani Kismat Ki” and ‘O Mere Sona Re’ song from Shammi Kapoor and Asha Parekh’s “Teesri Manzil”. Sources suggest that the actress will also be rapping a few lines for the new track.
However there is no news on the release date of “Yamla Pagla Deewana Phir Se” .

domain: celebrity


text:
Cranberry Pear Sauce made with fresh cranberries, Bosc pears, white wine, cinnamon and brown sugar is a delightful addition to your Thanksgiving table.
Let's see a show of hands. How many people use canned cranberry sauce on Thanksgiving? I always did. It was just what I grew up with and yes, I even liked the jellied version that had to be sliced. No judgment please! ☺.
That is until last year when I made my own version of homemade cranberry sauce after seeing how easy it was.
This year, I was ready to experiment with my own recipe and came up with this Cranberry Pear Sauce. I added the pears because I happened to have two laying around and thought it would give the cranberry sauce a nice flavor. It certainly did!
For this recipe you'll need the following ingredients:
Light Brown Sugar
How do you make Cranberry Pear Sauce?
To make this recipe, combine the wine, water and cinnamon in a medium saucepan over high heat and bring to a boil; then reduce heat and simmer for 15 minutes.
Add the cranberries, pears, and sugar to the pan and bring the mixture back up to a boil. Reduce the heat and allow to simmer for an additional 15 minutes.
The sauce will be done when the cranberries start to burst open. Remove the sauce from the heat and allow to cool completely before transferring it to a bowl.
Keep refrigerated in an airtight container until ready to serve. Can be prepared up to 2 days ahead of time.
With only five ingredients and a half hour of your time, you can have fresh cranberry sauce on your Thanksgiving table this year too. And I'll bet you will NEVER go back to the canned stuff again...trust me! ~Enjoy!
Visit the recipe index to search for more recipes by category.
More Homemade Cranberry Sauce Recipes
- Spiced Cider Cranberry Sauce
- Homemade Orange Cranberry Sauce
- Cabernet Cranberry and Blueberry Sauce
- Boozy Cranberry Sauce
- Apple Cranberry Sauce
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Cranberry Pear Sauce
- ¾ cup white wine
- ½ cup water
- ¼ teaspoon ground cinnamon
- 2 bosc pears (peeled, cored and chopped)
- 12 ounces fresh cranberries (rinsed)
- ¾ cup light brown sugar
- Combine the wine, water, and cinnamon in a medium saucepan over high heat and bring to a boil; then reduce heat and simmer for 15 minutes.
- Add the cranberries, pears, and sugar and bring back up to a boil. Reduce heat and allow to simmer for an additional 15 minutes.
- The sauce will be done when the cranberries start to burst open. Remove from the heat and allow to cool completely before transferring to a bowl. Keep refrigerated in an airtight container until ready to serve. Can be prepared up to 2 days ahead of time.
Could anything else be substituted for the wine? Thank you!
Thank you so much!
Carrie Farias says
I suppose you could just use water or maybe some apple juice or apple cider, though I've never tried it that way. Let me know how it turns out!
This sounds terrific--though I've got 2 open bottles of red wine which I don't think would be that radical of a departure. My family may applaud the lack of beets.
Carrie Farias says
I've made another version with red wine and it was just as tasty. I'm sure your family will love this recipe.

domain: food


Updated: 12/20/2013 6:12 PM
Created: 12/20/2013 1:36 PM WDIO.com
By: Travis Dill
Ashland Police will recommend first-degree homicide and attempted homicide charges for a 14-year-old male who allegedly shot and stabbed a relative Monday evening.
Police released the details at a press conference Friday afternoon. Police Chief Greg Bebeau said William Saari and his wife were raising the boy, but a normal, quiet night ended in tragedy.
“It was a very gruesome, disturbing crime scene. Things we don't like to encounter on this job,” Bebeau said.
He said preliminary reports show 52-year-old William Saari died from several gunshot and stab wounds.
Police responded to a home on Cary Street in Ashland Monday night about 9 p.m. Police said officers encountered a woman in stockings frantic on the street. She told the officers her husband was being stabbed in the home.
Captain Jim Gregoire said the incident spilled out the front door as officers approached.
"Mr. Saari came out of the house staggering. A shot was heard from behind him by the officers. Mr. Saari then fell over obviously from his injuries,” Gregoire said.
He said a veteran officer then exchanged gunfire with a 14-year-old male. Gregoire said the officer and suspect each fired twice without hitting anyone at the scene.
Gregoire said the suspect then retreated into the home and police heard another gunshot from inside.
“The suspect then exited the rear of the house onto the deck where officers gave commands that he obeyed and he was taken down and handcuffed and given medical attention,” Gregoire said.
He said the suspect's injury was a self-inflicted gunshot to the stomach. Police said the suspect received medial attention in Duluth. However the suspect was later transferred to a detention center in Wisconsin, and he is being held on a $250,000 bond.
Police said the officer involved in the shooting is on administrative leave. Police still have no motive for the incident, but formal charges are expected next week.
Wisconsin Makes Minnesota Offer on Tax Reciprocity
The neighboring states have been unable to reach a deal since a 40-year agreement expired in 2009. An agreement would simplify income taxes for the roughly 80,000 who live in one state and work in the other.
Minn. DNR Increases Target Wolf Harvest
The Minnesota DNR is increasing the target harvest for this fall's wolf hunt from 250 to 280. The DNR says the latest population survey estimates that there were 2,423 wolves living in Minnesota this past winter, which is 212 more animals than estimated the previous winter.
Update: Teen Killed in Douglas Co. Crash
The Douglas County Sheriff's Office says a Lake Nebagamon teenager was killed in a two-vehicle crash on Wednesday afternoon. 15-year-old Seth N. Stariah, a passenger in one of the vehicles, was pronounced dead at the scene.
U of M Reaches Milestone with Ash River Neutrino Detector
The University of Minnesota is celebrating a milestone in creating an experimental particle detector that it says could eventually yield important information about the beginning of the universe.
Missing Employee Found at Soudan Underground Mine State Park
Authorities have located 76-year-old Adrienne De Vries at the Soudan Underground Mine State Park. De Vries is an employee of the park, and lost her way when walking down a trail. The St. Louis County Sheriff's Department says she was transported to Ely Hospital to get checked as a precautionary.


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Isabella Rossellini Brings the Birds and the Bees from the Hunter Lab to the BAM Stage
Hunter graduate student Isabella Rossellini – the acclaimed actress, author and director – brings her study of animal behavior to a one-woman show at the Brooklyn Academy of Music.
In Green Porno: Live on Stage, Rossellini, who is pursuing a master’s in animal behavior and conservation at Hunter, wears Day-Glo costumes and communes with puppets as she mimics the reproductive rituals of assorted insects and crustaceans. Rossellini worked with screenwriter Jean-Claude Carrière to adapt Green Porno from her Sundance Channel video series of the same name.
The show, which BAM calls “a cheeky, delightful zoology lesson brought vividly to life by Rossellini’s singular flair for storytelling,” runs from January 16 to January 25 at BAM’s Fisher Theater.
Green Porno is almost sold out, but tickets may still be available through the BAM website.

domain: biology


text: EYECARE: Coronavirus BRIEFING: Crisis Response Tactics Tom Hanks Talks COVID By Staff Wednesday, July 15, 2020 1:45 PM Back in March, Tom Hanks and Rita Wilson were two of the first big-name celebrities to be diagnosed with COVID-19. Thankfully, Hanks and Wilson recovered, and have been donating plasma to help doctors learn more about the virus. Still, there's much about COVID-19 that is unknown, and testimony from those who have recovered can be invaluable. This week, Hanks appeared on The Late Show With Stephen Colbert and spent some time discussing his experience, including how his symptoms differed from his wife's. Head over to Mashable to learn more.


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domain: geography


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REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
> Journal Vol & Issue
Journal of Animal Environmental Science
Journal Basic Information
Journal DOI :
Korean Association for Livestock Housing and Environment
Editor in Chief :
Volume & Issues
Volume 19, Issue 2 - Dec 2013
Volume 19, Issue 1 - Sep 2013
Selecting the target year
The Effect of the Addition of Carbohydrate on the Concentration of Odorous Compounds in Pig Slurry
Hwang, Ok Hwa ; Yang, Seung Hak ; Jeon, Jung Hwan ; Kwag, Jeong Hoon ; Choi, Dong Yun ; Yang, Seung Bong ; Kim, Doo Hwan ; Cho, Sung Back ;
Journal of Animal Environmental Science, volume 19, issue 1, 2013, Pages 1~8
DOI : 10.11109/JAES.2013.19.1.001
Slurry treatments included peanut shell, palm golden fiber, almond hull, which was added 2% of the amount of slurry, and non-treatment control (n
A Study on the Integrated Unrolling, Cutting, and Softening System of Round Bale Silage for Pig Feeding (I)
Hong, Jong-Tae ; Kim, Hyuck-Joo ; Yu, Byeong-Kee ; Hyun, Chang-Sig ; Kim, Sung-Kee ; Yoo, Ji-Soo ; Hong, Young-Sin ; Seo, Hung-Dug ;
Journal of Animal Environmental Science, volume 19, issue 1, 2013, Pages 9~18
DOI : 10.11109/JAES.2013.19.1.009
Currently, there was no producing system of TMR for pig feeding in Korea. In this study, we examined unrolling, cutting, and softening for the round bale silage. We designed and developed the prototype system of round bale silage for pig feeding. Unroll method were lower chain conveying and upper belt conveying which includes an hydraulic vertical fodder knife. Gathering and cutting method were rotating auger and flywheel which have 10 cutters, input roller of 280 rpm, and cutter rotating speed of 1,750 rpm. Softening device was rotating hammer in inclined cylinder adjustable to
and rotating speed up to 1,300 rpm. The prototype system was integrated working for unrolling, cutting, and softening. We found that when the round bale silage in unrolling apparatus cut length of 20 cm to input cutting apparatus, the cutting performance was well in continuous working up to input rate of 1,000 kg/h, the softening apparatus was working well.
The Performance Analysis for Amounts of Sprayed Quantity by Using the Small and Medium-Sized Sprayer
Min, Byeong Ro ; Hong, Jun Taek ; Lee, Dae Weon ; Kim, Jea Youl ;
Journal of Animal Environmental Science, volume 19, issue 1, 2013, Pages 19~24
DOI : 10.11109/JAES.2013.19.1.019
This study is to promote domestic environmentally appropriately conditions for the range 60~70 m, the development of the small and medium-sized sprayer ability measurement that can be used as a general-purpose paddy fields, orchards, and not consolidated areas. The sprayer designed and manufactured that can spraying effectively distance to within 60~70 m. Distribution of sprayed pesticides were obtained and analyzed by measuring the weight. Performance analysed using the buckets were placed horizontally 12.5 m, 70 m vertical intervals by
, so total 68 buckets were placed. Total amounts of sprayed quantity was
and maximum spray distance was about 70 m. Reasonably sprayed region was 5 m~10 m vertically symmetrical. Showed a lot of spraying water in 5 m~40 m distance, and in 45~60 m tended to spraying water decreased slightly. Maximum spraying distance was 70 m.
The Comparison of Concentration of Volatile Fatty Acids, Ammonia, and Volatile Organic Compounds in Pig Slurry
Cho, Sung Back ; Yang, Seung Hak ; Lee, Jun Yeop ; Kim, Jung Kon ; Jeon, Jung Hwan ; Han, Man Hee ; Han, Duck Woo ; Jeong, Gwang Hwa ; Kwag, Jeong Hoon ; Choi, Dong Yun ; Hwang, Ok Hwa ;
Journal of Animal Environmental Science, volume 19, issue 1, 2013, Pages 25~32
DOI : 10.11109/JAES.2013.19.1.025
This study was performed to analyse the concentration of odorous compounds in the piggeries. Piggeries for different types of pigs include piglets, growing pigs, gestating and lactating sows. Slurry from these piggeries was sampled every month for chemical analysis. Short chain fatty acid (SCFA) was 9,862 ppm (piglet), 8,410 ppm (growing pigs), 6,791 ppm (fattening pigs), 3,508 ppm (lactating sows) and 1,687 ppm (gestating sows). Branched chain fatty acid (BCFA) was 1,634 ppm (piglet), 1,206 ppm (growing pigs), 868 ppm (fattening pigs), 493 ppm (lactating sows) and 185 ppm (gestating sows). Concentration of phenols was 209 ppm (piglet), 166 ppm (growing pigs), 127 ppm (fattening pigs), 85 ppm (lactating sows) and 36 ppm (gestating sows). Indoles was 18 ppm (piglet), 14 ppm (growing pigs), 8 ppm (fattening pigs), 6 ppm (lactating sows) and 4 ppm (gestating sows). Altogether, concentration of odorous compounds was decreased as pigs got aged.
A Farm on Broiler Chickens` Welfare in Korea
Cheon, Si-Nae ; Lee, Jun-Yeob ; Choi, Yang-Ho ; Park, Kyu-Hyun ; Kim, Doo-Hwan ; Song, Jun-Ik ; Jeon, Jung-Hwan ;
Journal of Animal Environmental Science, volume 19, issue 1, 2013, Pages 33~38
DOI : 10.11109/JAES.2013.19.1.033
We conducted investigations of the information and welfare of broiler chickens in Korea. The livestock housing of all broiler chicken farms were windowless type, bell feeder and nipple waterer were used, and stocking density was relatively higher (ranging from 18.2
) than RSPCA`s welfare standards for chicken hens (less than 19
). The ratios of sandwich panel, urethane form, slate, and steel plate in roofing materials were 61%, 21%, 13%, and 5%, respectively. The ratios of sandwich panel, urethane form, brick, and steel plate in wall materials were 61%, 21%, 13%, and 5%, respectively. The ratios of soil and concrete in flooring materials were 10% and 90%. The mist spray, fan, and cooling pad in cooling facilities were 42%, 32%, and 26%, respectively. Thus we believe that present data contribute to develop the animal welfare certification for broiler chickens and to improve animal welfare in Korea.
A Study on Filtration Effect of Anaerobic Digestion Wastewater by Composition of Filtration Layer Materials
Lee, Dong-Hyun ; Jeong, Kwang-Hwa ; Khan, Modabber Ahmed ; Kim, Jung-Gon ; Kwak, Jung-Hun ; Ahn, Heekwon ; Kim, Eun-Jong ;
Journal of Animal Environmental Science, volume 19, issue 1, 2013, Pages 39~46
DOI : 10.11109/JAES.2013.19.1.039
This study was carried out to compare the filtration effect of anaerobic digestion waste water by compost filtration bed. Three types of filtration systems were set for filtration test following to composition of bedding materials. Two filtration systems were filled with sawdust, rice-hull and wood-chip. And the other was filled with sawdust and rice-hull. Anaerobic digestion waste water was applied evenly on the surface of the filtration bed with spraying nozzle. The concentration of nitrogen, biochemical oxygen demand (BOD), suspended solids (SS) of anaerobic digestion waste water was decreased by filtration treatment. The total nitrogen content was decreased from 1,313 mg/L to 1,090~1,293 mg/L and BOD concentration was decreased from 529.7 mg/L to 125~162.3 mg/L, respectively. The SS content was decreased from 69~79% by filtration process. In addition, the electrical conductivity (EC) was decreased from 10.22 ds/m to 7.91~8.31 ds/m.
Effect of Aeration on Fertilization and Sludge Accumulation of Pig Slurry
Jeong, Kwang-Hwa ; Khan, Modabber Ahmed ; Lee, Myung-Gyu ; Kim, Jung-Gon ; Han, Duk-Woo ; Kwag, Jung-Hun ;
Journal of Animal Environmental Science, volume 19, issue 1, 2013, Pages 47~54
DOI : 10.11109/JAES.2013.19.1.047
Two types of reactors were set to investigate the change of characteristics of pig slurry by aeration during fertilization period. One system was equipped with air diffuser to supply oxygen to pig slurry for liquid fertilization, but there was no air diffuser in the other system. Air supply to the experimental systems was regulated by air flow meter. The reactors were set up in the laboratory to protect the pig slurry from external condition such as temperature and humidity changes. Maintaining optimal pH range in the experimental reactors is an important factor for liquid fertilization of pig slurry. In this study, pH ranges of aerobic reactor and anoxic reactor was 7.04~7.19 and 7.34~7.81, respectively. The temperature of aerobic reactors was
higher then indoor temperature. The amount of sludge accumulated at the bottom layer of non-aerated reactors was 4~5 times more than that of aerated reactors.
Callus Induction and Plant Regeneration Efficiency According to Tissue Culture Conditions in Teff grass (Eragrostis)
Lee, Ki-Won ; Moon, Jin Young ; Park, Hyung Soo ; Choi, Gi Jun ; Kim, Ki-Yong ; Ji, Hee Chung ; Hwang, Tae Young ; Lee, Sang-Hoon ;
Journal of Animal Environmental Science, volume 19, issue 1, 2013, Pages 55~62
DOI : 10.11109/JAES.2013.19.1.055
Teff grass is a warm season C4 annual grass that is used for dry hay, silage and haylage. We have developed a high-frequency plant regeneration system for teff grass via callus culture using mature seeds. It was revealed that mature seeds cultured on MS medium supplemented with 2 mg/l 2,4-D, 0.5 g/L proline, 0.5 g/L casamino acid and 3 g/L Gelrite under light condition produced the highest percentage of callus formation (91.9%). Addition of cytokinins (BA) at 0.0~0.5 mg/L to media containing 2 mg/l 2,4-D enhanced callus growth. The most suitable medium for plant regeneration from dehydrated calli was MS agar medium supplemented with 0.1 mg/l NAA, 1 mg/l BA, 0.5 g/L proline, 0.5 g/L casamino acid 3 g/L Gelrite which induced the highest percentage of calli forming shoots (47.0%). The shoots were rooted at the highest rate (100%) when transferred onto 1/2 MS medium and acclimated in greenhouse conditions.
In vitro Technique for Selection of Radiation Induced Mutants of Tall Fescue
Lee, Ki-Won ; Moon, Jin Young ; Ji, Hee Chung ; Choi, Gi Jun ; Kim, Ki-Yong ; Hwang, Tae Young ; Lee, Sang-Hoon ;
Journal of Animal Environmental Science, volume 19, issue 1, 2013, Pages 63~68
DOI : 10.11109/JAES.2013.19.1.063
In vitro culture and radiation techniques were used for obtaining mutants tin tall fescue. Endophyte free and friendly tall fescue cultivars Kentucky-31 and Jesup were used for induction of genetic variability through in-vitro mutagenesis. Mature seeds was used for callus induction on 6 mg/L 2,4-D. Actively growing and compact callus was treated with three different doses of gamma rays (10 Gy, 30 Gy and 50 Gy). Maximum proliferation and plantlets regeneration growth was observed in control and minimum at 10 Gy. Furthermore, the maximum number of tiller in the irradiated population was observed in 10 Gy. The treatments 30 Gy and 50 Gy exhibited negative impact on the tillering potential of the tall fescue plant. The object of this study was to develop protocols for mutation breeding in tall fescue through radiation techniques.
Effect of Conditioning Methods and Tedding Frequency on the Drying Rate and Quality in Italian Ryegrass Hay
Park, Hyung Soo ; Kim, Ji Hye ; Seo, Sung ; Jung, Jong Sung ; Lee, Sang Hack ; Lee, Ki Won ; Choi, Gi Jun ;
Journal of Animal Environmental Science, volume 19, issue 1, 2013, Pages 69~74
DOI : 10.11109/JAES.2013.19.1.069
A field experiment was carried out to determine the effects of conditioning methods and tedding frequency on the drying rate and quality of Italian ryegrass hay. Italian ryegrass was cut with three types of mower conditioners (un conditioned, impeller, roller) and tedded with rake-tedder once or twice daily during field curing. The field drying rate of Italian ryegrass hay was the highest in roller conditioner. Conditioning treatment shorten the date from 1 to 1.5 compare with unconditioned. Drying rate of Italian ryegrass plant had been affected by tedding frequency within 3 days after it was cut, but it was ineffective after 3 days. There is no effect on acid detergent fiber (ADF) and neutral detergent fiber (NDF) but effect crude protein (CP) and relative feed value (RFV) by conditioning treatment in nutritive value of Italian ryegrass hay.


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Swizz Beatz' Megaupload.com shut down by Department of Justice
Half-Puerto Rican rapper Swizz Beatz (aka Kasseem Dean) appears to be the CEO of website Megaupload.com, which was shut down yesterday by the Department of Justice and cited in a federal indictment in one of the largest criminal copyright cases ever brought by the United States.
Hacker group Anonymous immediately retaliated and suceeded in crashing the sites of the Department of Justice, the Motion Picture Association of America, and Universal Music Group. Beatz was not named in any federal papers and does not seem to own stake in the company, but he did help promote the website at its inception. In an ironic twist, though Megaupload is being accused of pirating copyrighted material like music, movies and videos, many celebs and musicians endorsed the site including, Kanye West, Kim Kardashian, and rappers P. Diddy and Will.i.am.
I have to say, I can sort of understand where Anonymous is coming from. The timing seems a little fishy, coming on the heels of the huge Internet protest led by Wikipedia to block the bills known as the Protect IP Act (PIPA) in the Senate and the Stop Online Piracy Act (SOPA) in the House--which happen to deal with just the kind of copyright infringement Megaupload.com is being charged with.
It's a spot on example of what a lot of folks are afraid of will happen if these kinds of bills pass. At this point, it seems like a pissing contest between the DoJ, anarchist hackers and some of the Internet's most powerful sites. Megaupload.com was listed as the 13th most influential website on the Internet, and got about 50 million hits a month--um, that's sort of a big deal.
It's going to be fascinating to see how this power struggle plays out. While I understand that the DoJ is trying to protect copyrighted material, it seems like the era of the Internet has ushered in a new way for consumers to interact with content. This involves cutting out the middle man and sure, this will piss off the likes of Universal Music and the Motion Picture Association of America, but in the end, us the consumers and the content creators are going to have to figure out a way to share the music, movies and videos we all love.
I advocate for Radiohead's strategy. They released their much anticipated seventh album "In Rainbows" as a digital download and had their fans pay what they could. You know what happened? Fans paid what they felt was a fair price and in the end, the average amount spent by consumers for the album was $10--and as opposed to Radiohead getting just cents on the dollar like they would have if they had released their album through a corporate record label, they were able to receive 100% of the profits.
That's what these corporations are really afraid of, and they should be. The industries that have grown around peddling wares of the creative class to the average consumer are going to continue becoming more and more obsolete as the world wide web provides ways of artists directly interacting with their fans, but that's not necessarily a bad thing.
Image via chicagofabulousblog.com/flick


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SYNTHESIS OF NEW DIARYL DERIVATIVES COMPRISING IMIDAZOTHIADIAZOLE MOIETY AS POTENTIAL ANTICANCER AGENTS
Authors: Chirag kumar J. Gohil1, Malleshappa N. Noolvi
Number of views: 222
Cancer is a class of diseases characterized by out-of-control cell growth. There are so many types of cancer. In case of Women, Breast Cancer ranks second among cancer deaths in women. Approximately 60% of all breast cancer patients have hormone dependent breast cancer, which contains estrogen receptors and requires estrogen for tumor growth. Aromatase, the enzyme responsible for estrogen biosynthesis, is a particularly attractive target in the treatment of hormone-dependent breast cancer.
In the present study we have reported the synthesis of some novel Diaryl Derivatives comprising 2-Amino Thiadiazole and Imidazothiadiazole moiety. These moieties are of interest because of structural similarity with the Letrozole, which is the potent Aromatase Inhibitor and their diverse biological activities and clinical applications.
We have reported the new series of Letrozole analogues to target Aromatase Enzyme. The reaction was monitored by Thin Layer Chromatography using suitable mobile phase. The Rf values were compared and the Melting Point of the derivatives was determined. It was found that they were different from each others. Further, these derivatives were characterized and confirmed by IR, 1H-NMR, 13C-NMR and Mass Spectral Studies. For Anticancer activity, the selected compounds were submitted to National Cancer Institute (NCI) for in vitro anticancer assay and were evaluated for their anticancer activity. Primary in vitro dose anticancer assay was performed in full NCI 60 Cell panel in accordance with the protocol of the NCI, USA. Compound 1 has a 73.7 % and Compound 4 has a 52.56 % growth Inhibition of Breast Cancer cell lines
Keywords: Anticancer, Breast Cancer, Aromatase Enzyme, Letrozole, Thiadiazole, Imidazothiadiazole, NCI-USA


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America Ferrera makes a Comeback on TV on The Good Wife
Tuesday, February 8, 2011
America Ferrera of the Ugly Betty fame is going to appear on TV again but this time, she won’t be ugly anymore.
America Ferrera has decided to join the cast of CBS’s The Good Wife which will be her first role on a television series after the successful experience of Ugly Betty which ended last year.
Ferrera is 26 years old and she has been assigned to appear on The Good Wife in the role of “a potential love interest for Alan Cumming’s character, Eli,” as reported.
She will appear in the episode which will be aired on February 22. She will remain on the show for at least two more episodes. She will be playing the character of a student of DePaul University majoring in economics. She “will play a central role in the political race for State’s Attorney,” the source says.
Along with America Ferrera, Jerry Stiller is also scheduled to appear on the episode of Feb. 22. He will be playing the role of a judge. Gary Cole is also set to appear on the same episode who will return as the love interest of Diane, played by Christine Baranski.
Short link: http://www.platotv.tv/s/xn5i9
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