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COVENTRY gran Barbara Judge has been told she CAN have a life-saving operation – just days after the Telegraph took up her case.
We revealed how Barbara, from Holbrooks, had been turned down for £15,000 surgery to fix a blood balloon that would kill her in seconds if it burst.
Now bosses at NHS Coventry have performed a dramatic U-turn and agreed to fund the 72-year-old’s operation.
They will also pay for a second city patient to have the same surgery, which had also previously been rejected.
NHS Coventry agrees to fund operation immediately
BARBARA Judge cannot stop smiling – and who can blame her?
Earlier this week the great grandmother from Coventry was facing a death sentence after being turned down for urgent, lifesaving surgery.
Now the 72-year-old can look forward to a bright future with her family – thanks to the Telegraph.
After we took up her case NHS bosses did a U-turn yesterday.
It agreed to fund the surgery immediately, and promised to pay for an identical operation for a second city patient, Michael Wade.
Barbara, from Holbrooks, said: “I am trembling with joy.
“This means the world to me and my family – I have never seen them so happy.”
In September Barbara was diagnosed with an aortic aneurysm – a blood balloon that could burst at any moment and kill her in minutes.
Specialists at University Hospital said she was too ill to survive open surgery, but she was a good candidate for state-of-the-art keyhole surgery to fit a tailor-made stent in her artery.
However, a funding panel at NHS Coventry refused to pay for the £15,000 operation last month.
It finally backed down yesterday following a Telegraph investigation.
Barbara’s daughter Caroline said: “Refusing Mum her surgery was a death sentence. Now a weight has been lifted from our shoulders.
“I haven’t stopped smiling.”
The Telegraph tracked down new research showing experts believed the op – a Fenestrated Endovascular Aortic Aneurysm Repair – was a viable alternative to open surgery.
Coventry MPs Geoffrey Robinson and Bob Ainsworth joined our campaign, calling on health secretary Andrew Lansley intervene personally to save their constituents.
Yesterday the Telegraph met city grandfather Michael Wade, who was turned down for the same operation on the same day as Barbara.
The dad of three said it was his only hope as his previous heart attacks and diabetes meant he would not survive open surgery.
He feared the stress of being turned down could cause a fatal heart attack or make the aneurysm rupture.
Wife Gill said: “I can’t sleep because I don’t know if he will still be alive in the morning.”
But as we spoke Michael received a telephone call from NHS Coventry telling him it would fund the op.
Michael, of Wyken, said: “This is incredible – we can hope again.
“I believe this operation will give me a new lease of life.”
NHS Coventry said it decided to fund the operations after it began to review its findings in preparation for the families’ appeals.
Alison Walshe, director of commissioning development said: “We feel that the original panel was not presented with the full information to consider the cases.
“As such we have made the decision to approve these cases with immediate effect and have contacted the patients accordingly.
“We sincerely apologise for the distress caused to the patients and families involved.”
Mrs Walshe said NHS Coventry would now draw up a policy for funding this operation in future.
Barbara’s daughter Caroline said: “I’m so happy I’ve been dancing around.
“I just can’t thank the Telegraph enough for making this


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Chester, Vermont - It is well known that roasted peppers are a delicious ingredient in salsa and other recipes. Drew's All-Natural has proven that double roasting the peppers is twice as nice by winning the Taste of Expo 2003 Award. The prestigious award was recently bestowed on Drew's new Double Roasted Salsa at Natural Products Expo East in September, the industry's largest trade show.
To create the award-winning Double Roasted Salsa, Drew Starkweather (Chef Drew) used a technique based on authentic traditions. Fresh green chilies are roasted over an open fire, peeled and then roasted again. "Since the peppers are peeled before the second roasting, the bitterness of the skins is eliminated from the flavor profile leaving only a smoky and rich roasted pepper taste," explains Chef Drew. "Double roasting is a painstaking process, and therefore it is rewarding to have the fruits of our labor recognized as an exceptional food by the "Taste of Expo" judges," he adds.
After the second roasting, the smoky chilies are blended and balanced with ripe tomatoes, cilantro and limejuice to create a fresh-tasting salsa. The other all-natural ingredients include fresh onions, cider vinegar, jalapenos, sea salt, garlic, cumin and black pepper.
Made in Vermont, Drew's Double Roasted Salsa has a Medium spiciness, and is offered in a 12-ounce container with an SRP of $2.99. The new, award-winning salsa is naturally GMO-free, low-carb, fat-free, vegan, dairy-free, low in sodium, wheat- and gluten-free and contains no added sweeteners.
Since 1995, Chef Drew has utilized his extensive experience as a chef in the restaurant business to create unique and delicious natural Salsas, and Salad Dressings that double as 10 Minute Marinades. "Chef Created...Nature Inspired," the dressings and marinades include: Thai Sesame Lime; Roasted Garlic and Peppercorn; Rosemary Balsamic; Romano Caesar; Garlic Italian; Soy-Ginger; Sesame Orange; Lemon Tahini Goddess; Shiitake Ginger; Kalamata Olive & Caper; and Smoked Tomato.
With products available in retail stores across the nation, Drew's All Natural has demonstrated its commitment to creating healthy, unique and high-quality foods that are offered at a reasonable price. For more information, visit the company website at www.drews.com or call toll-free at 1-800-228-2980. The website has a listing of stores that stock Drew's line of natural products and also contains recipes from Chef Drew developed during his 16 years in the restaurant business.

domain: food


Tamar Braxton and Mary J. Blige have new videos. Tamar gets sexy in the visuals for “Let Me Know” featuring Future, while Mary J. hits the streets of London in “Right Now”. Peep the visual treatments inside….
Lil Wayne is dropping subliminals on a new track with Young Thug titled, “Take Kare.” Is he popping off on his baby mothers Toya Wright, Nivea, Sarah Vivian and Lauren London? Decide for yourself inside….
The woman whom Keyshia Cole allegedly attacked at Birdman's crib has filed court documents. Get the deets on what she revealed inside and find out why "Hot N***a" rapper Bobby Shmurda isn't making any money.


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(Reuters) - Oscar-winning actress Halle Berry suffered a minor head injury while shooting a fight sequence for a movie in Los Angeles on Tuesday night and was treated at a hospital and released, her publicist said on Wednesday.
"She checked out healthy and was released. She'll continue production as planned," publicist Meredith O'Sullivan said in an email.
Berry, 45, is shooting "The Hive," a thriller directed by Brad Anderson and also starring Abigail Breslin.
An ambulance took Berry from the set in central Los Angeles to Cedars-Sinai Medical Center, and the set was shut down, the celebrity news website X17 reported. A hospital spokeswoman declined to say if Berry was treated there.
Barry hit her head on lights on the set of the 2004 film "Catwoman" but was not seriously injured, according to IMDb.com, a movie database.
She won the Academy Award for Best Actress for the 2001 film "Monster's Ball."
(Reporting by Daniel Trotta; Editing by Vicki Allen)

domain: entertainment


text:
What Oscar’s Best Picture Snafu Spells For ‘Moonlight’ & ‘La La Land’ At The B.O.; There’s A Surprising Takeaway
After its surprise Best Picture Oscar win last night, what now for A24’s Moonlight?
Quite similar to the recent Best Picture winners before it, i.e. last year’s Spotlight and 2015’s Birdman, Moonlight already is streaming in homes on transactional VOD and will hit DVD shelves tomorrow. Despite major chains’ refusal to book movies that are already occupying their second and third ancillary windows, exceptions typically are made for Best Picture winners. A24 will reveal… Read
UCLA Diversity Report Downplays Gains Made By Industry’s Women and Minorities
Downplaying the gains women and minorities have made in Hollywood in recent years – and the industry's efforts to increase those numbers – UCLA's “2017 Hollywood Diversity Report” says its goal is "to set the record straight with respect to the myths, half-truths, and excuses industry decision-makers have used to justify business-as-usual on the diversity front."
But the report, while breaking little new ground, actually paints a gloomier picture than its own data… Read
Oscars: Is ‘Moonlight’ Poised To Make History After WGA Original Screenplay Win?
Well that didn’t settle much!
For only the third time since 1984 (some 32 years ago), the Writers Guild and the Oscars are possibly going to have two different winners in the Original and Adapted Screenplay categories, though you can put an asterisk on that statistic since they are both likely to have Moonlight as a shared winner – but in two different writing categories. If I haven’t confused you enough, let me make this even more perplexing.
With tonight’s newly minted W… Read
‘I Am Not Your Negro’ Tops $3.2M, ‘Everybody Loves Somebody’ Opens at $1M – Specialty Box Office
This holiday weekend’s Specialty box office is mostly quiet with debuts, while key Oscar nominees are keeping their zest. At over $3.2M, Magnolia Pictures' documentary nominee I Am Not Your Negro, in its third weekend of release, has pulled ahead in cumulative gross of all but a few 2016 non-fiction releases. Pantelion/Lionsgate's Spanish and English romantic-comedy Everybody Loves Somebody bowed with a 3-day take of $1M in 333 theaters, by far the most for a new… Read
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Since 2013, Presidents Day weekend at the box office has had the added benefit of Valentine’s Day falling on or adjacent to the four-day holiday weekend. But not this year, which spells a dull weekend.
Try blaming the holidays for not coinciding, but the real culprit is a lack of great, new product popping off the tracking boards — the likely result of which is more moviegoers voting to stay home than previous Presidents Days. Last year’s Valentine’s/Presidents Day… Read
Pete Hammond’s Notes On The Season: Oscars Hope To Be Inspirational; ‘Kubo’ Breaks New Ground; Octavia Spencer Is ‘Hidden’ No More
A column chronicling conversations and events on the awards circuit.
Although not many automatically think “Oscar” when you mention Fifty Shades of Grey, it perhaps should be remembered that the 2016 film of the E L James uber-bestselling novel nabbed an Academy Award nomination for its song “Earned It," performed on last year’s Oscarcast by The Weeknd, who also was one of its nominated writers. The sequel — which had its raucous premiere, complete with masked ball… Read
Iran’s Oscar Nominee ‘The Salesman’ & Mexican Hit ‘Un Padre No Tan Padre’ Open Stateside – Specialty Preview
Pantalion will bow Mexican comedy Un Padre No Tan Padre in more than 300 locations this weekend in the wake of a battle royal President Trump has picked with America’s neighbor to the south. The film, about an intergenerational clash starring popular actor Héctor Bonilla, has been a big draw in Mexico since opening late last year. Trump also said he will seek a visa ban from visitors from Iran among other countries, prompting a star in Foreign Language Oscar-nominated The… Read
‘Dear Evan Hansen’ Defies Winter Chill At Broadway Box Office
An unlikely media sensation gets caught up in the Twitter-enhanced mythology that distorts his true nature as he becomes a national hero: Donald Trump? Evan Hansen? Both had big weeks in dark times (but while each character profits from alternative truths, only one sings. Also, he’s not real).
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In a speech at the World Economic Forum in Davos, Switzerland this morning, Chinese President Xi Jinping never uttered Donald Trump’s name, but his message for the U.S. President-elect was clear enough. Xi, who is the first Middle Kingdom head of state to address the annual gathering, kicked off the proceedings by quoting Charles Dickens’ A Tale Of Two Cities. “It was the best of times, it was the worst of times,” Xi said regarding the current contradictory state of the… Read
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domain: design


text:
Research Article Creative Commons, CC-BY
Selenium Content, Anthelmintic, Antioxidant and Antibacterial Activities of Artocarpus Heterophyllus Lam. From Ubangi Ecoregion in Democratic Republic of the Congo
*Corresponding author: Koto Te Nyiwa Ngbolua, Department of Biology, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Received: October 03, 2019; Published: November 14, 2019
Helminths are recognized as a one of major animal and human health problem and the gastrointestinal nematodes become resistant to currently available anthelminthic drugs; therefore, there is a foremost problem in treatment of helminths diseases. The main aim of this study was to assess the anthelminthic, antioxidant and antibacterial activities as well as the mineral content of ethanol and organic acid extracts of Artocarpus heterophyllus Lam leaves. The phytochemical profile and phenolic contents of leaves were determined by thin layer chromatography and the spectrophotometric methods. Phytochemical analysis revealed the presence of flavonoids, phenolic acids, coumarins, anthraquinones, anthocyanins, terpenoids, and the absence of alkaloids in this part of plants. Mineral composition carried out by the method of water and nitric acid and analysis by Inductively Coupled Argon Plasma Optical Emission Spectrometry (ICP-EOS) showed the abundance of different elements namely calcium, iron, potassium and selenium in this plant. Ethanolic extract and organic acid fraction exhibited dose-dependent paralysis of Benhamia rosea in the range concentrations from 0.625 mg/mL to 5 mg/mL in comparison with the standard drug Albendazole. ABTS and DPPH assays showed that these extracts can scavenge free radicals connected with their IC50 values ranging from 17.26 ± 1.66 to 152.1 ± 30.20 mg/m L. Oleanolic acid used such as standard and organic acid fraction showed a weaker capacity to scavenge DPPH radical. Bacteriologic analysis showed that E. coli and S. aureus are not sensitive to Artocarpus heterophyllus Lam. The findings indicated that the anthelminthic and antioxidant activities of Artocarpus heterophyllus leaves support the potential therapeutic interest of this species and could justify its use in Traditional Medicine.
Keywords: Anthelmintic activity; Antioxidant activity; Antibacterial activity; Artocarpus heterophyllus; Selenium
Over 80% of the African population relies on medicinal plants for the management of several diseases and to meet their primary healthcare . In the therapy of several ailments, traditional medicine is showing a bright future and as it is performed as a good clinical practice. Plants are known to be the source of several medicines such as anthelmintic drugs. However, helminths are recognized as one of the major problems in farms for the animal’s production and constitute a public health concern as well in the tropics. Most of diseases caused by helminths are of a chronic and devastating in nature; they probably cause morbidity and greater economic and social deprivation . Currently, gastrointestinal nematodes become more resistant to available anthelmintic drugs; this situation causes a serious problem in the treatment of helminthiases . However, the chemotherapy is and remains the only treatment and effective tool to cure and control helminth infections, as effective vaccines are not yet developed until then. The random use i.e. the overuse or the misuse of synthetic anthelmintic drugs can be the cause of resistance to these drugs by the parasites. Moreover, these drugs are unaffordable due their high cost . With respect to this alarming situation of resistance, a way can be paved for the use of herbal medicines as alternative anthelmintic and could help in the prevention of resistance development. In low-income countries, plants are used in ethnoveterinary and are a source of many potent and powerful drugs . Artocarpus heterophyllus Lam. called jackfruit tree, is a species of tree in the Artocarpus genus (Moraceae) . It has been reported that Artocarpus heterophyllus is a good diuretic and laxative remedy. In the Democratic Republic of the Congo (DRC), the leaves of jackfruit tree are used for their anthelminthic properties mainly on animals .
To our knowledge, few investigations reported on the chemical constituents and the biological properties of this species. The main aim of the current work was to investigate on the anthelmintic, antioxidant and antibacterial activities of ethanolic extracts and organic acid fraction.
Plant Material Collection
The selection of plant species used in this study was based on previous ethnobotanical surveys . The leaves of Artocarpus heterophyllus were harvested at around the University of Kinshasa, precisely at the student hostel called “Plateau des étudiants” located in Lemma municipality, Kinshasa province, DRC. This species gets identified at the Institute National d’Etudes et de Recherche’s Agronomies’, Department of Biology, Faculty of Sciences, University of Kinshasa. This sample was dried out in room temperature (±27°C) at the Molecular Bio-Prospection Laboratory, Department of Biology for two weeks and then ground to obtain fine powder for further analyses
Chemicals and Reagents
All solvents used were of analytical and HPLC grade and purchased from Merck VWR (Leuven, Belgium). Caffeic acid, Chlorogenic acid (purity: 95%), Gallic acid (purity: 97%) was purchased from Sigma-Aldrich. Rutin (purity ≥99%), is quercitrin (purity ≥99%) and, quercetin (purity ≥98.5%) were HPLC grade and purchased from Extrasynthese.
Preparation of Extracts
The dried and powdered plant material (50g) was repeatedly extracted with 400 ml of ethanol (95%) by cold percolation for 48 hours . The filtrate obtained was concentrated to dryness under reduced pressure using a rotary evaporator. Organic acid fraction (triterpenic acids) was extracted as follow: the powdered stem bark of Artocarpus heterophyllus (40g) were macerated with 400 mL of dichloromethane-methanol-NH5OH (100:1:1; v/v/v) and then percolated with 300 mL of the same solvent mixture at room temperature. The extract was concentrated under reduced pressure until 100mL (pH 10). The resulting solution was then mixed with citric acid 5% (1:1; v/v) to precipitate organic/triterpenic acids. The resulting fractions were evaporated to dryness on an evaporator apparatus. All extracts were weighed and kept in dark inside hermetic flasks at 4°C.
Thin Layer Chromatographic Analysis: The phytochemical screening was performed on the aqueous and organic extracts for the identification of alkaloids, saponins, total polyphenols, flavonoids, tannins, anthocyanins, leuco-anthocyanins, quinones, terpenes and steroids following the standard protocol as described by Bruneton  and Tiwari et al. .
Total Phenolics Content: Total phenolic content of methanolic extracts (Methanol 80%) was determined according to the Folin- Ciocalteu method as described previously . A calibration curve of gallic acid (0.025-0.4 mg mL1) was prepared, and phenolic contents were determined in triplicate from the linear regression equation of this curve. The results were expressed as milligrams of gallic acid (GA) equivalent per gram of dried matter
Total Flavonoids Content: The flavonoid content of the extracts was determined by using the UV-Vis spectrophotometry method. The results are expressed in mg equivalent of quercetin per g (mg QE/g) of dry vegetal material .
Total Anthocyanins Content: The determination of anthocyanin content of the extracts was performed in accordance with the procedure reported by Bahati et al. .
Determination of Mineral Content
The determination of mineral content was carried out by the method of water and nitric acid and analysis by Inductively Coupled Argon Plasma Optical Emission Spectrometry (ICP-EOS). The method with water and nitric acid, has the principle of dissolving the sample in a mixture of 5 mL of distilled water placed in PM60 Teflon bombs (Analytikjena 40Bar) containing 0.3g of the sample which was heated at 60°C and 10 mL of nitric acid (HNO3 65%) (Merck) was added. The mixture was kept at the room temperature for 30 minutes in order to allow the oxidation to occur and later cover the bombs first with caps and then covers previously stripped with HNO3 / H4O (v/v, 1: 1). The bombs were placed in the high frequency microwave mineralizer (Analytikjena AG Top wave: 2.5 Ghz, Germany) controlled by microcomputer by choosing the vegetable leaves mode as a digestion mode at 180°C, 50 bars for an hour. At the end of mixing, the digester stops by letting the bombs rest for 3 hours until completely cooled. The cooled analyte is thus carefully transferred by filtration on Whatman filter paper, bombs to 50 mL volumetric flasks previously stripped. In order to reduce the initial volume to 50 mL with distilled water and then place 13mL of analyte in 15mL conical flask previously stripped for reading by Inductively Coupled Argon Plasma Optical Emission Spectrometry (ICP-OES) [Optima 8300 Perkin Elmer, USA]. The analysis was performed in triplicate. The calibration of the ICPEOS is performed using the working standard prepared from the commercially available standard multi-element solution 3 at two points (1mg/L and 2.5mg/L, Perkin Elmer, USA). The most appropriate wavelength, gaseous argon flow, plasma stabilization and other ICP-EOS instrument parameters for minerals are selected and measurements are made in the linear range of the working standards used for calibration.
The working conditions were:
Instrument: ICP-EOS [Optima 8300 Perkin Elmer, USA];
Power of Rf: 1500Watt;
Plasma gas flow (Ar): 8L /min;
Nebulizer: 0.70L / min;
Auxiliary gas flow (Ar): 0.2L / min;
Viewing size: 5-22 mm;
Copy and playback time: 1-5s (maximum 45s);
Flow time: 1s (maximum 10s);
Evaluation of Radical Scavenging Activity
The evaluation of the antioxidant activity was performed using the ABTS and DPPH assays in accordance with Kapepula et al. protocol .
In Vitro Anthelminthic Activity
The in vitro anthelmintic activity of Artocarpus heterophyllus was evaluated as per the method reported by Yashaswini . The tested samples prepared from the ethanol and organic acid (dichloromethane) leaf extracts were tested for their anthelminthic activity and two earthworms collected in Kinshasa city (Benhamia rosea and B. itoleisis) were used as animal model. The anthelminthic activity was evaluated on adult earthworms, Benhamia rosea due to its anatomical and physiological resemblance to the gastrointestinal nematodes. The animals were divided into 4 groups or batches of 3 worms each. The worms of group I were released into a plate containing a solution of distilled water which served as negative control. The worms of group II were released into a plate containing Albendazole in different concentrations (5 mg/mL, 2.5 mg/mL, 1.25mg/mL and 0.625 mg/mL) which served as standard (positive control). The worms of group III and IV were released into the separate plates containing solution of samples (Organic acid fraction and ethanol extract) at different concentrations as follows 5 mg/mL, 2.5 mg/mL, 1.25 mg/mL and 0.625 mg/mL per group respectively. All the test samples were prepared in distilled water. In the study observations were made for the time taken to paralysis and death rate of individual worms. The time for paralysis was noted when no movement of any sort observed. Death was concluded when the worms lost their motility completely and failed to respond even after a touch with the needle followed by fading of their body colors. The earthworms in control group (group Ι) were alive up to 48 hours of the experiment. Mean values of paralysis time and death time of Benhamia rosea and Benhamia itoleisis earthworms were calculated separately.
The antibacterial activity of Artocarpus heterophyllus leaf extracts was performed following the micro-well dilution method on two bacteria strains namely Escherichia coli and Staphylococcus aureus. And the minimum inhibitory concentration (MIC) was obtained .
Each concentration was tested in triplicate for each assay, and at least 3 different assays were performed. All results were expressed as mean values ± standard deviation (SD). The statistical analysis was performed with GraphPad 7.0 (GraphPad Software, San Diego California, USA). One-way analysis (ANOVA) was used and the level of statistical significance was set at p < 0.05. The IC50 values were calculated with GraphPad Prism 7.0 under application of the function “log (inhibitor) vs. normalized response-variable slope” after converting the concentrations into their decimal logarithm
Results and Discussion
Phytochemical analysis performed by TLC showed the presence of phenolic compounds as major compounds. These phenolic compounds are responsible of antiradical activity of plants, since this potential is strongly attributed to them . By comparing with the used standards, phenolic acids such as cafeic acid and chlorogenic acid are identified in the plant [13,14]. These results were like those previously described that indicate the presence of flavonoids in the leaves of A. heterophyllus . Figure 2 shows the presence of coumarins (blue fluorescent spots) in almost all the extracts of the tested samples. Concerning anthraquinones, Figure 2 shows the presence of anthrones (red spots) [16,17]. The presence of anthocyanins was indicated in all extracts as described in the chromatogram of Figure 2. The analysis of Figure 2 shows the coloration observed in the chromatographic profiles of each sample (violet, orange) and indicates the presence of terpenes including irridoids in all extracts. These results were like those previously described by Prakash et al. and Sivagnanasundaram and Karunanayake [14-17] in A. heterophyllus  that indicated the presence of these chemical compounds in A. heterophyllus. The presence of these compounds in a plant species could confer some biological properties, such as antioxidant activity and anthelmintic activity . The alkaloid test gave a negative response using Draggendorff reagent. The results of secondary metabolite assays are presented in Table 1 below
Legend: GAE/100g Equivalent of gallic acid (GAE) per g of dry extract; QE/g Equivalent of quercetin (QE) per g of dry extract and CE Equivalent of Cathechin
From Table 1, it is noted that A. heterophyllus is rich in phenolic compounds. The presence of polyphenol is abundant followed by the flavonoids and anthocyanins. Previous studies reported that this plant contained phenolic compounds with the flavonoids as the most abundant [19,20]. Studies have shown that not only extrinsic factors (such as geographic and climatic factors), genetic factors, but also the degree of maturation of the plant and the duration of storage has a strong influence on the content of polyphenols [21,22].
The mineral composition of the leaf extract of Artocarpus heterophyllus is given in the figures.
The analysis of both figures above showed that calcium is the microelement which has a remarkable predominance in terms of concentration in the leaves of this plant followed by potassium compared to other detected microelements (magnesium, sodium and phosphorus) (Figure 1). While Selenium is the microelement that has a high content followed by iron, nickel and manganese while other microelements such as Barium, Cobalt, Zinc and Copper present low concentration (Figure 2). Soetan et al.  reported that minerals are inorganic nutrients, usually required in small amounts from less than 1-2500 mg per day, depending on the mineral. As with vitamins and other essential food nutrients, mineral requirements vary with animal species. For example, humans and other vertebrates (like ruminants) need large amounts of calcium for construction and maintenance of bones and normal function of nerves as well as muscles. Phosphorus is an important constituent of adenosine triphosphate (ATP) and nucleic acid and is also essential for acid-base balance, bone and tooth formation.
Magnesium, copper, selenium, zinc, iron, nickel and manganese are important co-factors found in the structure of certain enzymes and are indispensable in numerous biochemical pathways. Sodium and potassium are important in the maintenance of osmotic balance between cells and the interstitial fluid. Cobalt is required as a constituent of vitamin B12 and its metabolism, the same as for vitamin B12. In addition to its role in vitamin B12, cobalt is also a cofactor of enzymes involved in DNA biosynthesis and amino acid metabolism . Deficiencies of cobalt in ruminants cause anorexia, wasting of skeletal muscle, fatty livers, hemosiderosis of the spleen and anaemia . The interactions between nutrition and diseases, nutrition and drug metabolism have been reported. Excessive intake of some minerals can disrupt the homeostatic balance and causes toxic side effects.
The antioxidant activity of tested extracts determined by ABTS and DPPH assays is presented in Table 2 and is expressed as IC50 values. IC50 is the amount of antioxidant necessary to decrease the initial concentration of radical by 50%. A lower IC50 value indicates a higher antioxidant activity. Oleanolic acid, organic acid fraction and ethanolic extract of A. heterophyllus showed less IC50 values inferior to 100 μg/mL in the ABTS test. For the DPPH test, the oleanolic acid and the organic acid fraction of A. heterophyllus seem to be inactive at tested concentrations. The capacities of various extracts to inhibit radicals vary substantially in each type of test. This difference may be due to the qualitative and/or quantitative range of secondary metabolites of the extracts. Furthermore, it should be noted that the IC50 value obtained in the ABTS test is interesting than that of the DPPH test. This difference in activity is attributed to the mechanisms of reactions. In fact, the ABTS radical reacts with hydrophilic and lipophilic compounds at the same time while DPPH° radical reacts only with hydrophilic compounds . A lower IC50 value of A. heterophyllus indicates a higher antioxidant activity. To our knowledge, it is for the first time that the antioxidant activity of the organic acid fraction of the leaves of A. heterophyllus is reported.
In Vitro Anthelmintic Activity
The In Vitro anthelmintic activity is depicted in Table 3. It was found that the shorter concentration of the extract become faster due to the paralytic effect and the higher concentration of the extracts due to death rate for all earthworms. The ethanol and organic acid extracts of the plant with concentration of 5 mg/ mL, 2.5 mg/mL, 1.25mg/mL and 0.625 mg/mL produced dosedepend paralysis. Ethanol extract of the leaves of A. heterophyllus showed paralysis time and death rate at 5 mg/mL in 28.00 ± 4.20, respectively while the organic acid extract gave paralysis and death rate in 37.00 ± 1.40 as compared to the standard were paralysis time and death rate was at 5 mg/mL during 18.00 ± 2.8 respectively. The findings displayed a hopeful prospect on anthelminthic activity of this plant, and this could be used by humans in the management of gastrointestinal nematode infection. Moreover, the findings indicated that the paralysis time taken for albendazol is near to that of the paralysis time of the ethanol extract. Phytochemical screening tests showed that the leaves of A. heterophyllus contained the phenolic compounds . It was reported earlier that the tannins and phenolic were known to interfere with the energy generation in helminth parasites by uncoupling oxidative phosphorylation or they bind to the free protein of the gastrointestinal tract of the worms and led to the death while the presence of flavonoids and polyphenolic compounds were also responsible for anthelmintic activity . The presence of these compounds in a plant species could confer some biological properties, such as antioxidant activity, antibacterial activity as well as the anthelmintic activity .
Table 3:The in vitro anthelmintic activity of ethanol and organic acid extracts of leaves of A. heterophyllus against Benhamia rosea and B. itoleisis.
Legend: OAE: organic acid extract; EtOH: ethanolic extract; GP: group
These results were like those previously described by Shekhunat and Vijayvergia  and Yashaswini et al.  who reported a higher anthelminthic activity with ethanol extract of the seeds of A. heterophyllus Lam. It was reported in the literature that the anthelminthic drugs having the imidazothiazole core as Albendazole have the property to be fixed on the nicotinic receivers at acetylcholine of the parasitic worms as thus mimics the action of acetylcholine. This fixing induces the permeability change of the post-synaptic membrane causing a muscular contraction, followed by the spastic paralysis and finally, the death of the worms . On the contrary, the polyphenols like tannins would have the capacity to bind to proteins and, consequently would modify the physical properties and biochemical parasitic worms. Indeed, they would interact with the worms while being fixed at the macromolecules of the cuticule or of the sheath of the L3s larvae (containing proteins rich in proline and hydroxyproline) or would fix them to the secrete enzymes over the worms and would block their activity . It was considered that the interactions between tannins and proteins of the exoskeleton (the cuticule), the alimentary canal even the genital structures of the worms would affect some essential functions like the nutrition or reproduction .
The antibacterial avtivty of the leaves of A. heterophyllus is presented in the Table 4. The results of antibacterial activity showed E. coli and S. aureus are not sensitive to A. heterophyllus with the CMIs>1000 μ g/mL) This antibacterial activity is however weak (MIC>1000 μ g/mL)  and would be due to the presence of phenolic and triterpenic compounds present in the tested extracts. The bioactivity would be due to the nature of their wall . Indeed, S. aureus is a positive gram bacterium. Its wall is thick (several layers) and would be the pharmacological target of the biologically active compounds present in A. heterophyllus leaves. These results corroborate with studies on the antimicrobial properties of the secondary metabolites of plant origin [32,33].
Légend: OAE: organic acid extract; EtOH: ethanol extract; +: gram positive; -: gram negative
The present study evaluated the chemical composition, minerals compound, the anthelminthic, antioxidant and antibacterial activities of the leaf extracts of A. heterophylly. The findings revealed that the leaves of A. heterophyllus contained various secondary metabolites such as the anthocyanins, coumarins, anthraquinones, flavonoids, phenolic acids and terpenoids. The leaves of A. heterophyllus contained also various minerals such as calcium and selenium. Organic acid extract revealed an interesting antioxidant activity. The ethanol and organic acid extracts exhibited significant anthelminthic activity. The antibacterial activity of the plant extracts was weak toward tested bacterial strains. The tested samples can be evaluated further for other pharmacological properties, which may be useful in the design of new anthelmintic drugs.
The authors express their gratfull to “Agence Universitaire de la Francophonie (AUF) for Grant N° DRACGL-2017-007. They thank the Laboratory of Systematic, Management of Natural Resource, Faculty of Agronomy Science, University of Kinshasa and Professor Millau Empwal for their technical supports.
Author has no conflict of interest.
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- Lengbiye EM, Koto te Nyiwa N, Gédéon NB, Lin MM, Olivier PN, et al. (2018) Artocarpus heterophyllus Lam. (Moraceae): Phytochemistry, Pharmacology and Future Directions, a mini review. J of Advanced Botany and Zoology 5(3): 2348-7313.
- Damien STT, Ngbolua KN, Lengbiye EM, Dorothée DT, Bienvenu MM, et al. (2016) Chemical composition and bioactivity of Canarium schweinfurthii stem bark extracts from DR Congo against Sickle cell disease and associated bacteria. Journal of Pharmacognosy and Phytochemistry 5(4): 181-187.
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- Kapepula PM, Mungitshi PM, Franck T, Mouithys Mickalad A, Ngoyi DM, et al. (2016) Antioxidant potentiality of three herbal teas consumed in Bandundu rural areas of Congo. Nat Prod Res 31(16): 1940-1943.
- Yashaswini T, Akshara KAM, Prasad K, Kumar MD, Akshaykumar K (2016) Anthelmintic activity of seed extracts of Artocarpus heterophyllus. IOSR Journal of Pharmacy and Biological Sciences 11(5): 19-23.
- Gédéon B, Inkoto C, Colette M, Claudine T, Lengbiye EM, et al. (2017) Assessment of Antisickling, Antioxidant and Antibacterial Activities of Some Congolese Taxa: Aframomum alboviolaceum (Ridley) K. Schum, Annona senegalensis Pers. and Mondia Whitei (Hook. f.) Skeels. American Journal of Laboratory Medicine 2(4): 52-59.
- Chandrika UG, Jansz ER, Warnasuriya ND (2004) Analysis of carotenoids in ripe jackfruit (Artocarpus heterophyllus) kernel and study of their bioconversion in rats. J Sci Food Agric 85(2): 186-190.
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- Sivagnanasundaram, Karunanayake KOLC (2015) Phytochemical Screening and Antimicrobial Activity of Artocarpus heterophyllus and Artocarpus altilis Leaf and Stem Bark Extracts. OUSL Journal (9): 1- 17.
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domain: literature


Singer Chase Forever has dropped a new single Pull Me Down off his forthcoming ‘Unappreciated’ album.
Pull Me Down is produced by Gafacci, one of Ghana’s most talent producers around.
Song Title: Pull Me Down
Artiste Name: Chase Forever aka Fianko Bossman
Who Inspired The Song: Jesus and everyone around me, since I became an artiste.
About Song: It talks about my struggles from the industry to the close relations, I call a family. I feel unappreciated. I am planning my upcoming album launch and everybody around me has stopped picking my calls. It’s crazy and it’s almost as if there’s some agreement among the people around me to make sure I don’t drop the album. So I decided to put my frustrations in this song.”


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Clip #1 embedded video under cut—Thank you door!!
[Spoiler (click to open)]
Claire and Jenny will stop at nothing to save Jamie in Saturday's "Outlander," and today, Access Hollywood has an exclusive sneak peek from the episode.
In the clip, Claire (Caitriona Balfe) and Jenny (Laura Donnelly) take a Redcoat soldier hostage as they try to find out information about where Jamie is.
"This is -- it's a huge shift and the wonderful thing about it is that you see Claire and Jenny get to – it's almost like they go on a female Western. They get to be the rescuers and I love that that's being flipped. ... It's really fun, fun stuff," Caitriona previously told Access of the scenes involving the two women on a mission to save Jamie, in the Highlands of Scotland. "Laura and I were running around on our horses with our guns. It was just so much fun."
SISTERS DOING IT FOR THEMSELVES YA'LL!


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For your beach reading enjoyment you might want to try something like The Lemon Grove. It’s about forbidden desire and family dynamics and it’s set in sun-soaked Mallorca. This is a smart, erotic read and an uncomfortable, edgy (and addicting) little book.
Book Info: Audiobook received for review from Audiobook Jukebox. Running time: 6 hours 12 minutes. Read by: Kate Reading. Also available in e-book or hardcover, 224 pages from Doubleday.
Jenn and her husband Greg are on summer holiday in Deià, a small coastal village in Spain. Greg’s 15-year-old daughter Emma arrives for the last week of their stay, with her 17-year-old boyfriend tagging along. Jenn and Nathan have an immediate sexual attraction that Jenn tries to suppress, and her feelings turn into a dangerous obsession that threatens to destroy her family.
The arrival of Emma and Nathan bring all these other issues to the surface and disrupt Jenn and Greg’s idyllic vacation. Jenn starts to reflect on her feelings on aging and desire, her rocky relationship with her teenage stepdaughter, and her stale marriage. Nathan is the shiny new toy who makes Jenn see everything differently.
This situation gets very tense on the island as Jenn comes to terms with her feelings for Nathan. It all feels taboo and uncomfortable, and I had a hard time finding whom to root for in this story. I felt like I was watching a foreign film that really pushed my boundaries. Helen Walsh has a unique voice, and makes the most of the setting and characters, and ooh what a chilling ending!
I listened to the audiobook of The Lemon Grove (I alternated with the kindle edition since I really couldn’t put it down!) Kate Reading is the narrator and she has a British accent like the characters, and uses different voices and dialects to help identify each character. Nathan’s voice is working class and cocky like the character, and Emma’s voice is appropriately bratty. Reading’s pace was on the slow side for me so I sped it up to 1.5 and that was perfect. You’ll probably want to tuck a print copy into your beach bag, but the audiobook is a serviceable alternative. Listen to a sample:
Read The Lemon Grove if you like: Crossover books, smart erotic reads, exotic settings, family drama, and you are comfortable reading about taboo relationships


China has reported sending the second Type 054A/P frigate to Pakistan . The innovatively progressed warship is required to upgrade Pakistan’s maritime protection and prevention/deterrence abilities altogether.
The event denotes the completion of 70 years of Pakistan-China conciliatory and diplomatic relations based upon outstanding obligations of fellowship and trust, as per an assertion the Pakistan Navy sent to the Global Times at almost the same time.
Report: China to Send its Most Advanced Frigate Warship to Pakistan
The Pakistan Navy has gotten developed four Type 054A/P frigates from China since 2017, with the primary ship launched back in August 2020.
As revealed by Geo News, the launch of the second Type 054A/P frigate was held at Hudong-Zhonghua Shipyard in Shanghai.
Contrasted to the past Chinese frigates, the new form has better air guard ability. It is outfitted with an improved radar framework. More powerful rockets measure with a more drawn outreach, Zhang said, noting that the Type 054A frigate likewise has a-list secrecy capacity.
As indicated by the Pakistan Navy proclamation, all the ships are being conveyed according to the arranged timetable.
As indicated by Chief of the Naval Staff of the Pakistan Navy Admiral M Amjad Khan Niazi in a new selective meeting, these warships will be the absolute most innovatively progressed foundation of the Pakistan Navy Surface Fleet, furnished with the advanced surface, subsurface, and hostile to air weapons, sensors and battle the executive’s frameworks.
“These boats will help [the] power of our armada and altogether add to keeping up harmony and security in the locale,” he said.
Zhang Junshe, the PLA Naval Military Studies Research Institute, told the Global Times in a past meeting that the Type 054A, on which the Type 054A/P is based, is China’s most advanced frigate.


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Are you in the mood for some deep house grooves? Well then, you'll want to check out the latest release from Dan Mela and Lady Blacktronica!
The song is called "Drive Me Crazy." Have a listen ...
The press release says ... It comes courtesy of What Ever Not label head Dan Mela and renowned deep house innovator Lady Blacktronika. The pair have teamed up to present 'Drive Me Crazy', a lament to the classic sound of Chicago house. Featured are three takes on the original and one fantastic remix from up and coming Crème Organization producer Alex Israel.
"Drive Me Crazy" is available on iTunes and other digital outlets.

domain: artistic


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Valerian Might Just Become The Next Big Space Opera Cult Movie
The first teaser trailer for Valerian and the City of a Thousand Planets finally arrived this week and it was spectacular. I used the word Spectacular because it is freaking spectacular, it’ll probably be 2017’s most amazing-looking thrill ride through space.
Based on the French graphic novel Valérian and Laureline, Valerian and the City of a Thousand Planets is the latest film from Luc Besson, who’s best known for The Fifth Element and Lucy.
The series focuses on the adventures of the dark-haired Valérian (Dane DeHaan), a spatio-temporal agent, and his redheaded female colleague, Laureline (Cara Delevingne), as they travel the universe through space and time. Valérian is a classical hero, kind-hearted, strong and brave who follows the orders of his superiors even if he feels, deep down, that it is the wrong thing to do. On the other hand, his partner Laureline combines her superior intelligence, determination and independence with sex-appeal. Influenced by classic literary science fiction, the series mixes space opera with time travel plots.
The original French graphic novel had already inspired Star Wars in many ways like the Valérian and Laureline’s XB982 astroship and the Millennium Falcon are very similar.
The production studio has licensed the first 9 books in the comics series, which means if this movie is successful, we could be in for much more to come.
Valerian and the City of a Thousand Planets will hit theaters from July 21, 2017. Meanwhile for a closer look at some of the best shots and moments from the Valerian teaser trailer, check out our gallery of high-res stills below.


| Nov 15, 2013
| 11:00 AM
"I always feel like a vague failure in L.A.," said Greta Gerwig, sitting in a movie theater in the heart of Hollywood.
The actress, 30, had flown from her home in New York to partake in the Los Angeles Times' Young Hollywood round table at AFI Fest last...
| Nov 6, 2013
| 5:21 PM
Tom Cruise is declaring his devotion to Suri Cruise, his daughter with ex-wife Katie Holmes, in court documents related to his $50-million lawsuit against a couple of tabloids.
It's one of the first times the A-lister has opened up about his divorce,...
| Oct 29, 2013
| 5:06 PM
Nothing like a Victoria’s Secret model to change one’s mind about marriage!
Just ask Maroon 5 frontman Adam Levine. The crooner paid a visit Monday night to "The Tonight Show With Jay Leno," and Leno teased him about previously rejecting the...
| Oct 29, 2013
| 3:34 PM
Jane Seymour and husband James Keach have made their split official: The former "Medicine Woman" has filed for legal separation.
The British actress filed documents in Los Angeles Superior Court last week to break from her actor-director husband of more...
| Oct 23, 2013
| 3:44 PM
When George Clooney and Sony Pictures said Tuesday that the release of “The Monuments Men” would be delayed from mid-December to an unspecified date in 2014, they set off a round of speculation--and potential scrambling.
| Oct 22, 2013
| 7:11 AM
“Dancing With the Stars” sure likes to keep us on our twinkle toes. In this sixth week of competition, the producers decided to throw a couple of bedazzled wrenches into the usually well-oiled ballroom glitterverse.
First, they added an...
| Sep 26, 2013
| 7:44 PM
One of the most anticipated movies of 2013 won’t come out until 2014.
“Foxcatcher,” Bennett Miller’s fact-based story of wrestling and murder starring Steve Carell, is being delayed until next year to allow Miller to finish the...
| Sep 24, 2013
| 7:00 AM
Wang Jianlin is the wealthiest man in China, owns the biggest theater chain in the world and wants to create the world's largest movie studio in his home country.
Hollywood is taking the billionaire chairman of Dalian Wanda Group Corp. seriously, but...
| Sep 19, 2013
| 10:33 AM
It's been five years since Zac Efron graduated from the "High School Musical" franchise, the guileless film series that established the young star as a mom-approved heartthrob.
Yet even with his Disney Channel days in the rear-view mirror, the actor has...
| Sep 19, 2013
| 6:30 AM
Since joining the judging panel on "American Idol" last year, Keith Urban's constantly reminded of the one thing that separates the winners from the runners-up: hard work.
"The other day, I was getting a bit worn down by people who were coming in to...
| Sep 18, 2013
| 4:14 PM
New York-based designer Joseph Altuzarra has taken the spotlight in L.A. this week, co-hosting an Emmys kick-off party, and designing the interior of the green room where stars will hang out backstage during the awards show Sunday night.


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A West-coast city with a reputation for “cracking down on street preachers” now faces legal action from one of those speakers, who appears to have the upper hand.
Anti-abortion activist Mark Mayberry is suing the city of Portland, Ore., for violations of religious and freedom of speech rights.
Ray Burke, an Oregon-based attorney for the Pacific Justice Institute and Mayberry’s legal counsel, said that Mayberry often goes to public parks, fairs and events in Portland to start conversations with people and share the gospel. In June, he was in Tom McCall Waterfront Park with a sign defending the unborn, passing out tracts, and talking to people about abortion in relation to Christianity.
A park ranger approached Mayberry and requested that he leave the park. Mayberry refused, and the ranger accused Mayberry of harassment and for not obeying “reasonable” orders, which resulted in a citation and ban from entering the park for 30 days.
Burke told The Epoch Times that “the Portland city code says that we only have to obey reasonable orders, and if somebody is at a park engaging in free speech and an officer tells them to stop, by the code’s own language, that is not a reasonable order. And so Mr. Mayberry was not obligated to obey it, and he didn’t.”
Burke said the encounter was peaceful, with no physical confrontation.
During a city hearing on the incident, the city auditor determined that the ban and citation were unconstitutional and overturned both.
The Oregonian reported that Hearings Officer William Guzman wrote in his ruling: “The Park Officer’s direction to stop engaging passersby with information regarding his Christian beliefs against abortion was not reasonable. Appellant was not required to comply with this park officer’s unconstitutional attempts to silence Appellant’s message.”
Guzman determined that Mayberry’s activities were protected under the First Amendment.
Burke said that while Mayberry is grateful for his vindication, his client is not content and wishes to send a message to the city about its history of violating free speech and religious rights.
“Portland has a reputation for, basically, cracking down on street preachers,” said Burke. “Mr. Mayberry is not the first street preacher I’ve represented, you know, who has had problems with Portland police or other law enforcement officers relating to sharing the gospel.”

domain: news


So you have learned some chords, jammed with friends and are ready for your first gig. Aside from a guitar, lead and amplifier there are some essential items that guitarists will find handy as they start performing gigs.
My guitar gig bag contains a large array of items that are necessary to have in preparation for any gigging situation.
Inside my Guitar Gig Bag:Tuner - essential for any musician. Any practice, rehearsal or lesson should start with making sure your instrument is in tune. Guitar tuners are inexpensive these days and are also helpful when needing to use alternate tunings. You can also get tuner apps on your phone!
Strings - don't let your first time on stage be ruined by a broken string. My personal string choices are:
Electric Guitars - D'Addario 10 - 46 gauge - these allow me to get a heavier tone than thinner strings and still allow me to bend the strings easily enough. The thicker the string the less chance you will have of breakage and the more volume and sustain they can also give.
Acoustic Guitars - DR 12 - 52 gauge - acoustic strings are always much thicker wire as they need to produce more volume and sustain. I like these strings because they hold their tone over many performances and break less than other brands I have tried.
Picks - find which guitar pick suits your playing. There are many different sizes, shapes, thickness and materials they are made from.
Leads - always have one spare lead with you. I have had three leads stop working at gigs in the last month.
Wire Cutters - helpful when restringing guitars.
Power Adapters - for powering guitar pedals you may use.
Slide - for playing some blues and variety in lead playing.
Powerboard and extension lead - make sure you will have enough to be powered up.
Kettle Leads - most amplifiers and speakers run off these cables .
Gaffa tape - holds up band banners, keeps down leads, tapes on broken guitar straps.
Screwdrivers - one flathead and one Philips head for quick repairs and tightening loose screws.
Microphone Leads - for acoustic guitar DI boxes or microphones.
Torch - stages are dark places when setting and packing up.
Capo - never know when a singer plays a song in a different key
Allen Keys - to change string height (action) or for locking tremolo guitars
Fuses - the simplest repair to an amplifier is changing a fuse. Hopefully if you find your amp in disrepair at a gig will just mean replacing a blown $2 fuse. Get the appropriate one for your amp.
Arming yourself with a kit of these tools will mean you are ready for any hurdles you may face at your first gig and in future. This is just the starting point of your musical journey and a brief introduction to the world of gigs and performances.
About the Author:By Rhys Lett, owner of the Eastern Suburbs School of Music in the eastern suburbs of Melbourne, Australia. We have more of these practical insights to music available to you on my website blog at www.essm.net.au we would be happy to help you further.


When your heating and cooling system stops working, you need the help of a reliable, experienced, local service professional that can diagnose the problem and repair your air conditioner or furnace at a fair price. You can count on The Home Depot's licensed and insured heating and cooling professionals for all your heaters, air conditioning units, and any ventilation needs.
If you hear clicking that is followed by a hum or buzz, you’re probably hearing the fan motor attempting to start without the boost it needs from the capacitor. You can almost always conclude that the capacitor has failed. Sometimes you can get the compressor fan spinning (clockwise) by pushing it with a thin stick or long screwdriver poked through the grille. But the chances are good that this might work for one cycle, but the capacitor will fail next time the AC goes on. It’s best to replace the capacitor.
"Very impressed. Returned call within 24 hours. They came out the same day I spoke with them and made the repair within 25 minutes. Very low service call fee. I had another repair service out two weeks earlier and after 3 service calls and the central air still not fixed and temperatures in the high 90's, it was such a relief to have a company identify the problem, have the necessary part with them and fix the problem."
You should also have air ducts cleaned after recent water contamination or water damage to prevent mold; after renovations or remodeling to ensure debris and dust didn’t settle in the vents and ducts; if you are having problems with allergies or asthma; or when you are moving into a newly purchased home, especially if the previous owners smoked or had pets. The National Air Duct Cleaners Association (NADCA) recommends getting your air ducts cleaned every three to five years, or every two to three years in regions where homeowners use their air conditioning and heater for many months of the year, while the EPA suggests homeowners have duct cleaning done as needed.
As the first Carrier Factory Authorized Dealer in the area, Nerthling's Heating and Air Conditioning is recognized for exemplary business practices, customer loyalty, and industry knowledge. Our service team continues factory training, staying updated with ever-evolving techniques and technology. We remain current with product development, qualifying us to identify equipment that accurately suits your needs and allows for maximum efficiency. We install proven reliable systems with a track record of durability, in a variety of configurations, guaranteeing an ideal match to your expectations. We specialize in the installation, service, and repair of air conditioning, heat pumps, furnaces, boilers, geothermal options, generators, air quality solutions, and ductless HVAC.
Moncrief provides a wide range of services from high-quality energy-efficient systems, tune-ups and inspections, as well as repairs in the Roswell and Marietta areas. As a full-service heating and cooling company, we stay up-to-date on the most economical and energy-efficient systems available for your home or business. In addition, our technicians are well-trained in a wide range of systems to provide quality and cost-efficient furnace service, repairs and installation.
We are service professionals! As licensed contractors and specialists in the field of heating and air-conditioning, we have the tools, the equipment, and the experience to keep your equipment running smoothly all year long. If it is emergency service that you need seven days a week, we are available to assist you! To help reduce service emergencies, we offer service agreements to keep your comfort system running at peak performance.
Reinstall the access panel and disconnect block. Turn on the circuit breaker and furnace switch. Then set the thermostat to a lower temperature and wait for the AC to start (see “Be Patient at Startup,” below). The compressor should run and the condenser fan should spin. If the compressor starts but the fan doesn’t, the fan motor is most likely shot. Shut off the power and remove the screws around the condenser cover. Lift the cover and remove the fan blade and motor (photo 7). Reinstall the blade and secure the cover. Then repower the unit and see if the fan starts. If it doesn’t, you’ve given it your best shot—it’s time to call a pro.
We take great pride in our crew, choosing the best and brightest to represent R.S. Andrews in the face of an emergency. Our HVAC contractors boast not only unparalleled skill but also a friendly and professional demeanor. All of our work comes completely guaranteed, and we won’t rest until your emergency has been resolved to your full satisfaction!
How often you should clean your air ducts depends on your situation. If you or someone in the home has asthma or is acutely allergic to certain airborne materials or pollen, regular duct cleaning may be helpful. The Environmental Protection Agency doesn’t have an official position on the necessity of air duct cleaning unless the ducts have been contaminated by rodents, insects or mold, or you are aware of particles blowing out through the vents. The EPA recommends you have your air ducts cleaned on an as-needed basis. The National Air Duct Cleaners Association (NADCA) suggests having air ducts cleaned every three to five years.
Service Experts Heating and Air Conditioning was founded with the determination of offering customers with the top of the line heating and cooling practices in the industry. Since it started, Service Experts in Raleigh has been committed to our area, offering the finest HVAC (Heating, Ventilation, Air Conditioning) products and services in the area. If you are interested in more details about your regional HVAC leaders, simply dial us at 919-578-4329 or set up an appointment with us using our online form.
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In addition to the information below, see these two articles for the general care and maintenance of your air conditioner: Preparing Your Air Conditioner for Summer and How to Replace Furnace & AC Filters. Most noteworthy, you should replace the filters at least twice a year, before the heating and cooling seasons. For information on furnace problems, please see Furnace Not Working.
Nerthlings Heating and Air Conditioning is proud to be rated as Erie, PA’s leading heating and cooling company. We’ve been serving Erie PA and the surrounding areas for over 60 years, handling all of their HVAC needs. For furnace repair, furnace service, or a new heating system installation at your home/business, Nerthling’s is the company to call if you want the job done right. We are also experts at AC repair, service & installation, as well as generator installation. Our other services include boiler repair and service, geothermal HVAC, heat pumps and ductless heating & air conditioning. To learn more about our high-quality HVAC services, give us a call today at 814-240-2297!


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BY: Edan Runge
Balinese hotel worker, Made (real name concealed), has been laid off without financial support as COVID-19 devastates Bali’s tourism industry.
In a series of interviews throughout April, Made, 26, said COVID-19 has left him worried about his future working at a five-star hotel in Nusa Dua: “There are no longer any guests that come and stay in the hotels. I was sent home at the start of April.”
Balinese authorities began closing tourism sites to slow the spread of SARS-CoV2 on March 23.
On April 1, the Indonesian Government announced a full ban on foreign arrivals and transit passengers through the country. Made has returned to his family home in Singaraja, where he is living with his elderly mother and brother, whose wife has just given birth. Made says measures to mitigate the pandemic have also wiped out his family’s income. “My mum usually sells fruit in town, but she can’t now because she has to stay home.”
Made’s brother’s on and off construction work remains the only source of income for the family of five living together.
“Of course, this has become very concerning,” said Made. Neither his employer nor the provincial government have provided financial support during the crisis. “We only hope that the government gives us some food aid because that’s the most important thing. We don’t want to starve to death,” said Made.
On April 20, Made’s disadvantaged family received a care package from his village government which only lasted few days. Made said: “It’s not enough. We’re a big family, especially now we’ve got a new baby and have to buy essentials for her too.”
His employer told him that he was ineligible to receive assistance because he was not yet a permanent staff member, despite having worked at the hotel for two months. Made’s workplace was contacted for comment but did not respond.
Fortunately for Made, some friends he made during three years of sponsored education at Melbourne’s Camberwell Grammar School donated care packages of foodstuffs and basic necessities to his family through the non-profit ‘Let’s Help Bali (COVID-19)’ Facebook group, created by Ellie Griffin to allow Australians to donate care packages to Balinese families in need of assistance.
Ms Griffin said concerns about thousands of Balinese whose livelihoods have evaporated due to COVID-19 inspired her and friend Amanda Rialdi to establish ‘Let’s Help Bali’. “Myself and Amanda have Indonesian families… We worry about our friends plus all the other people who rely on tourism to pay for their meals.”
“In the last week around 800 care packages have gone out to people all around Bali.”
According to Ms Griffin, “There’s starting to be a bit more help [from government] but not for those who really need it.”
Awaiting some support, Made said: “We can’t do much other than stay home and pray that this pandemic ends quickly so things go back to normal.”
He hopes to receive some shifts maintaining the empty hotel grounds this month.
Balinese authorities began closing tourism sites to slow the spread of SARS-Cov2.
The Indonesian Government announced a full ban on foreign arrivals and transit passengers through the country.
Made was sent home from work.
Made’s family received a ‘Let’s Help Bali’ care package donated by his school friends from Melbourne after communicating to them that they “had no help whatsoever” in their village.
190,000 furloughed Indonesian tourism workers were put on to a paid four month preemployment program which aims to retrain them for new jobs. Made was not among them.
Made said he is unsure whether to apply for the pre-employment card or look for other job opportunities: “That seems impossible at the moment given so many jobs have closed down and there are no vacancies.”
The Indonesian Ministry for Tourism allocated IDR 500 trillion to save the tourism sector during the COVID-19 emergency.
Made became an uncle to his brother’s child, adding another family member needing support amidst the uncertainty of this health and economic crisis.
Made’s family received a small care package from his Singaraja village government.
Still without sufficient assistance from local authorities or his employer, Made received another care package donated by his Australian friends.
Made’s employer said Made was ineligible to receive assistance because he was not yet a permanent staff member.


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The life and works of Palestinian filmmaker Michel Khleifi will be celebrated in London at the Shabbak Festival featuring his films and the films of others. Khleifi produced the West Bank’s first documentary film in 1980 “Fertile Memory”Michel Khleifi
For many years, Michel Khleifi was the ultimate voice of Palestinian cinema. Emerging from the ashes of PLO resistance cinema, the Nazareth-born, Brussels-educated and based filmmaker was the leader of the so-called ‘new Palestinian cinema’ of the ’80s ─ a movement that ventured to break the dominant stereotypical representation of Palestinians and create a new space that links Palestine’s destroyed past with its austere present and uncertain future.
Always deemed controversial by Arab commentators and foreign critics alike, Khleifi’s films were the first to capture Palestine’s true soul, the first to depart from the jingoistic works of previous generations to present rich portraits of a complex reality; of an atypical land and its atypical inhabitants.
In nine films that range between documentary and fiction narratives, Khleifi has developed a recognisable set of symbols, themes, characters and aesthetics that have become a key part of Palestine’s collective memory.
He made history in 1980 with the documentary “Fertile Memory,” the first feature produced in the West Bank; yet it wasn’t until 1987’s “Wedding in Galilee” that Khleifi became an artist of international renown.
Winning the FIPRESCI prize at the Cannes Film Festival in 1987 and the Golden Seashell award at the San Sebastian Film Festival the same year, “Wedding” ─ a chronicle of wedding in small Palestinian village disrupted by the attendance of intrusive Israeli guests ─ was the film that put Palestinian cinema on the world film map.
To celebrate his 65th birthday, the London-based Shubbak Festival of contemporary Arab Culture is celebrating Khleifi’s career in its current edition by having him curate this year’s film programme. The line-up is comprised of a selection of his own films along with a number of European and Arab titles that address some of the themes and concerns of his own work.
Arab and European films presented in the programme include Maroun Bagdadi’s gritty Lebanese Civil War drama, “Out of Life” (1991); Rainer Werner Fassbinder’s classic cross-culture love story, “Ali: Fear Eats the Soul” (1974); and Kamal Aljafari’s Palestinian experimental documentary of displacement and agonising stillness, “Port of Memory” (2010).
- Muslim American woman challenges unresponsive Congressman Sean Casten in March 19 Democratic primary - November 21, 2023
- More than 50 journalists killed in Israel-Gaza war - November 21, 2023
- On World Children’s Day, Israel has turned Gaza into a Graveyard for Children: - November 20, 2023


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Army Awards Contract for 155mm Munition
General Dynamics Ordnance and Tactical Systems Inc., St. Petersburg, Florida (W15QKN-23-F-0565); and Nammo Perry Inc., Perry, Florida (W15QKN-23-F-0571), will compete for each order of the $488,656,334 fixed-price-incentive contract for manufacturing, assembly, inspection, packaging and delivery of 155 mm M119A2 propelling bag charges. Bids were solicited via the internet, with two received. Work locations and funding will be determined with each order, with an estimated completion date of September 6, 2028. Army Contracting Command, Newark, New Jersey, is the contracting activity.

domain: geography


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By Bruce Sayler
Extra free throw shooting might be a bigger part of high school basketball practices when drills begin in Montana next week.
The one-and-one sanction has been taken from the rulebook in a move made last spring by the National Federation of State High School Associations. So, it is likely more two-shot fouls will be in occurrence.
“The purpose (of the change) is to eliminate the one-and-one,” John Kinzle, Montana Officials Associate district delegate for the Butte basketball pool, said Friday moments before he and Sean Ryan were to work a junior high school game at Butte Central High School. “It is to eliminate the rough play on the first shot and to speed the game up.”
The seventh foul charged a team in a half had previously meant the opponent was given the bonus opportunity at the free throw line from then on following common, or non-shooting, fouls. The shooter would receive a second free throw if he or she made the first. Kinzle said players converging from the lanes trying to rebound or screen out a rival on a missed first free throw often caused “rough play” with elbows out and buttocks pushing against competitors.
“Sometimes, there’d be injuries,” the veteran ref said.
The new rule is similar to what was implemented in college women’s basketball a few years ago. There are no more one-shot free throws. Teams will be limited to five fouls per quarter before the bonus opportunity is awarded. The sixth foul will cause the offending team to send the opponent to the line for two shots. The team count will be reset at the start of each quarter.
“Under the old rules, if a team was in the bonus in the third quarter, it was also in it for the fourth quarter and that tended to be a long game,” Kinzle said. “This new rule should speed the game up.”
Kinzle indicated that it is expected trailing teams will foul less in later moments if the penalty is to allocate more free throws to the opponents now that there will be no or lesser tempted gamble on the one-and-one. If a team was behind on the scoreboard in prior years, it seemed automatic that team would commit fouls to cause clock stoppage and hope to rebound a possible missed foul shot.
“The rationale is to give the teams better flows,” Kinzle said. “College women went to this rule recently and everything seems to be fine with it.”
Coaches seem to be taking a wait-and-see approach, but with sprinklings of help and optimism.
Butte Central head boys’ basketball coach Brodie Kelly said he didn’t have an opinion formed.
“I’m pretty indifferent about it,” he said. “I’m actually not sure of the logic behind that rule change. I wish they would change individual fouls to six to foul out.”
Kinzle predicted the change to be an improvement.
“I think it will be a better game for us,” he said. “And, we think it will be better for the kids, too, because they can get into a flow and get rid of so much stop-and-go. Games should be shorter.
“We have to see, but I think it might speed up the ends of games.”
Bryan Arntson reffed basketball before taking the reins of the Butte High girls’ program two seasons ago.
“I actually love (the change),” he told Paul Panisko in a KMBR sports web site article earlier this year. “I’ve been saying for years that they need to change. From both a referee and a coaching standpoint, I think that it allows the kids to adapt to how the game is being reffed and adjust. It also helps with the flow of the game. A lot of games have teams shooting free throws for over a quarter of each half.
“It does change end-of-game scenarios without the one-and-one, but, overall, I think it’s a great change.”
Ryan said he really likes the rule as used in college women’s basketball.
Kinzle said another new rule fans will notice deals with ball inbounds after play stoppage. He said the ball used to be inbounded from a designated zone nearest where the ball left the court. Now, he said, only four spots on each side of the midcourt stripe will be used for re-entry.
The 28-foot mark on each side of the stripe and each side of the floor will be the sites on the side of the court. Spots three feet each side of the free throw lanes at each end will be used for end-of-court inbounding.

domain: sports


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Theme: Family Games
Still in shrink-wrap. Rules included in English, German, French and Italian.
In the Caribbean Sea, Pirates attempt to board European colonialist galleons to plunder their treasures. In Tortuga each player plays the part of the leader of a Pirate Clan. He/She tries to board ships in the best way, while simultaneously preventing his/her opponents from successfully boarding. To do this the player will have to choose which ship to board, the best weather conditions and the best strategy to use during combat.
Beating great and powerful ships and gaining the most precious treasures, allows the player to earn honor points. The pirate with the most points wins the game.
Can be played by 4 players with 2 decks.

domain: game


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Chikondi Foundation president Bishop John Mambo says Zambia is losing its status as beacon of peace on the continent and Zambians looking like fools because of the high indiscipline in the ruling party.
Bishop Mambo told the Post newspaper that the indiscipline in the ruling party has led to acting President Guy Scott isolating himself from PF campaigns because he has been treated with disrespect from the time President Michael Sata died. The Edgar Lungu PF has tried to portray Dr. Scott as a very bad man and anarchist.
He said there was indiscipline in the ruling party with all leaders fighting each other and that they were now trying to divide the church.
Meanwhile sources have disclosed that Edgar Lungu’s team is under pressure to convince Dr. Scott to join in the campaign but Scott seems to be uninterested due to the indiscipline levels and the court proceedings over the disputed presidency which is being claimed by both defence and justice minister Edgar Lungu and commerce deputy minister Miles Sampa.

domain: politics


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Simon Pegg was one of the more surprising stars to show up in The Boys, yet he did not come back in later seasons. However, that is about to change with upcoming fourth season of the superhero show.
According to Deadline, the Shaun of the Dead star has signed on to return as Hughie’s father Mr. Campbell in the upcoming fourth season of The Boys, which is currently in production. He will be joined by three new cast members Rosemarie DeWitt (The Staircase), Rob Benedict (Supernatural), and Elliot Knight (Call of Duty: Modern Warfare II), with DeWitt tapped for the role as Hughie’s mom.
Pegg has briefly spoken not being asked back for Season 2. He told Collider in 2020 that he “pleased to be a part of it,” but they “got [him] out of the way.
The Boys is an irreverent take on what happens when superheroes, who are as popular as celebrities, as influential as politicians, and as revered as gods, abuse their superpowers rather than use them for good. It’s the powerless against the super powerful as The Boys embark on a heroic quest to expose the truth about the supergroup known as “The Seven.” The show retains most of the comics’ boundary-pushing violence and sexuality while exploring the dark side of superhero celebrity and fame.
The Amazon Studios series stars Jack Quaid, Laz Alonso, Tomer Capone, Karen Fukuhara, and Karl Urban, along with Erin Moriarty, Antony Starr, Dominique McElligott, Jessie T. Usher, Chace Crawford, Nathan Mitchell, Claudia Doumit, and Colby Minifie.
Season 3 featured the addition of Supernatural’s Jensen Ackles as the infamous Soldier Boy, Katia Winter as Little Nina, Miles Gaston Villaneuva (Law & Order True Crime) as Supersonic, Sean Patrick Flanery (The Boondock Saints) as Gunpowder, Nick Wechsler (Revenge) as Blue Hawk, and Laurie Holden (The Walking Dead) as Crimson Countess.
The series, based on the comic book series created by Garth Ennis and Darick Robertson, is created by Evan Goldberg and Seth Rogen, who are also responsible for AMC’s Preacher, and Supernatural creator Eric Kripke.
Seasons 1 to 3 are available for streaming on Prime Video.