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|• 4 lb Salmon filet|
|• 1 ½ Cup Canning Salt|
|• ½ Cup Brown sugar|
|• 2 Tbs Molasses|
|• 2 Oz Tequila|
The salmon preparation starts with the brine. I really don’t measure anything but here it is. In a plastic pail (2 or 3 gallons) I will fill it to about ¾ full of water. I like that size pail because it fits into the refrigerator. Add canning salt starting with about a 1 ¼ cup and mix it into the water. I will then add salt until a raw egg almost floats. Add about a handful of brown sugar, ½ cup or so. Add a tablespoon or two of molasses. On occasion, I add a couple of shots of tequila for an interesting flavor.
The filet(s) should be trimmed up, clean and fresh if possible. Salmon doesn’t freeze too well even if it was frozen in a vacuum bag. So fresh is best. With the availability of fresh salmon in the stores and the prices often less than $10 per pound it is worth it to buy a fresh filet for a special occasion. Don’t ever try and figure what salmon cost per pound if you’re going to catch them on your own. $10 per pound is pretty reasonable. Submerge the salmon in the brine. Put the pail in the refrigerator and let it soak for 24 hours, give or take.
Take the salmon out and rinse in cold water. Place the salmon filets on paper towel to wick any moisture off the filet. I put a fan on the filets and let them air dry for an hour of two before putting them in the egg. You will get a better color that way.
When the filets are dry I season them. You can sprinkle them with Cajun seasoning, fresh gound black pepper, even maple syrup or molasses. Black pepper seems to be the favorite.
12 to 24 hours ahead of time, you’ll need to prepare your wood chips. I use apple wood. I use a couple of good handfuls of chips and if I have it, some sawdust. I soak it in beer or water.
I prepare the egg by putting in about ¾ batch of charcoal and get it going to about 1/3 to ½ burn. At that point I add the apple wood. I squeeze the liquid out of the sawdust if I’m using it. I don’t worry too much about the temp. at this point because the wet chips and sawdust will take some of the heat out of the fire. I immediately invert the plate setter, place the grill on top and put the fish on.
Close the top and bottom dampers to ¼ inch. Put an electronic thermometer in the top. The temp. should be around 175 F. I let it slowly build to 200 to 210 F. That is the target. I start closing the dampers from there to maintain the temp. in the 200 F range.
The fish will smoke fairly quickly. At about 1 ½ hours the fish will be done. I may let the temp. creep up a little at the end if a dryer smoked fish is desired. Generally I leave the fish on a little less than 2 hours. You can always tell if it is completely cooked by pulling on a pin bone in the front portion of the filet. It should come out easy and a tiny bit of clear juice should come out of the hole.
Remove the fish to a wire rack to cool. Make sure it is well back from the counter edge because the dog likes smoked salmon too. ENJOY!
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Bright red to reddish brown are these delicious dehydrated slices of roped tomatoes. Chewy, sweet and tangy the tomatoes are immersed in oil making them soft and easy to use in any recipe. Add sun-dried tomatoes to salads, soups, pizza, pasta, sandwiches, frittatas, eggs and more!
Office # 103, A, 2nd Floor, Uni Center, I. I Chundrigarh Road, Karachi, South Saddar Town
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The wholeness of high quality roasted almonds and honey grinded together gives rise to this pure and creamy nut butter.
A wonderfully textured and flavored butter made with fresh cream and added with honey and cinnamon. If you're tired of…
Figs are also a good source of iron, magnesium, potassium, B vitamins, as well as vitamin K. D
This butter gives a feel which is delightful for your palates. Made by fresh cream, mixed with olives and jalapeño's…
Our peanut butter is light and creamy made from the finest quality peanuts from Parachinar. It's perfect to indulge in…
The perfect condiment infused with chilli peppers that can be paired with almost everything from soups to lasagne, your favorite…

domain: food


The Mazda CX 7 engine is one of the most popular sport sedans on the road today. Its sleek design, high-tech interior, and powerful engine make it an attractive choice for drivers of all kinds. However, you may be wondering about the engine’s performance in terms of gas mileage. Below are some tips to help you understand what you should expect.
2007 model year
Mazda CX-7 is an SUV that debuted in 2007. It was designed as a crossover vehicle with a sporty attitude. The Mazda CX-7 has a 2.3-liter turbocharged four-cylinder engine with 258 lb-ft of torque.
The Mazda CX-7 was a strong competitor to the Honda Pilot and Nissan Murano. Despite being a four-door SUV, it was very roomy. Mazda had a good track record for their vehicles, and the CX-7 was a success.
There were several desirable features included on the CX-7. They included leather upholstery, four-wheel ABS, traction control, and stability control. Also standard was an AM/FM stereo with single CD, power door locks, and cruise control. A navigation system with rearview camera was also available.
Mazda’s active torque-split four-wheel drive system sends up to 50% of available power to the rear wheels on slippery surfaces. This allows for all-weather driving. However, there is no low-range gearing. If you need to take your SUV off the road, this isn’t the car for you.
The Mazda CX-7 offers two different engine options. You can choose the 2.5-liter MZR four-cylinder, which has 161 hp, or the 2.3-liter DISI Turbo, which has a 258 lb-ft of maximum torque.
The 2.5-liter non-turbo engine is not the smoothest, but it’s still a decent choice. Other issues include noisy wheel bearings, sway bar links, and front lower control arms.
2009 model year
If you’re looking for a five-passenger sport sedan, the 2009 Mazda CX-7 is a good option. It has excellent performance, and a great ride and handling. However, it isn’t as well equipped as last year’s model.
The Sport and Touring trim levels offer a lot of standard features. For instance, the Touring has leather upholstery, heated front seats, and a rear bumper guard. In addition, the Grand Touring comes with a retractable cargo cover, electroluminescent gauges, and heated outside mirrors with integrated turn signal repeaters.
All of the 2009 models are MP3 capable. The Sport and Touring can also be fitted with a Bose stereo. A technology package adds a voice-controlled touch screen navigation system. There’s also a rear park-assist system with a rearview camera. Lastly, the Preferred Equipment Package includes a cargo net.
While the Mazda CX-7 is a good choice for couples who occasionally need to transport guests or items, it’s not a great choice for families. The cabin is compact and has limited headroom and legroom.
The turbocharged 2.3-liter four-cylinder engine produces 244 horsepower and 258 foot-pounds of torque. This is enough power to get the CX-7 to 60 mph in around 7.7 seconds. But the turbo feels like it’s peaky at times. Also, the six-speed automatic transmission takes time to downshift.
2011 model year
Mazda CX-7 is an attractive mid-size crossover SUV. It offers a unique combination of sport-sedan and utility-vehicle attributes, and it is also a lot of fun to drive.
The Mazda CX 7 engine comes in two different powertrains: a non-turbocharged 2.5-liter four-cylinder engine that produces 161 hp, and a 2.3-liter turbocharged four-cylinder that produces 244 hp. Both engines are paired with five-speed automatic transmissions and are available in front-wheel drive or all-wheel drive models.
The 2.5-liter is rated for 20 mpg in the city and 28 mpg on the highway, while the turbocharged engine provides 17 mpg in the city and 21 mpg on the highway. However, the turbocharged model is a thirsty performer. In Edmunds testing, it took 9.8 seconds to reach 60 mph.
The 2.5-liter mazda cx 7 engine offers fuel economy on par with most V-6 mid-size sedans. However, the 2.3-liter turbocharged four-cylinder is thirsty.
Mazda CX-7 models come standard with side curtain airbags and anti-lock brakes with brake assist. The base i SV model adds power door locks, power windows, AM/FM stereo, and a single MP3-compatible CD player.
With its two-tier dash and unique hooded gauges, the Mazda CX-7 interior is reminiscent of a cockpit. Seats are comfortable and offer good legroom. There are a variety of controls and buttons, and the dashboard is topped with an eye level upper screen section.


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Oma Sue's Blog
Hi – I’m Sue Reyzlik. I recently realized my life-long dream of building a writing hut in the backyard. The writing hut serves as a creative space and home office for Oma Publishing. This blog will be intermingled with family history, varied experiences and insights on being a Grandma (Oma), creating my special backyard space, as well as, my “retirement” career as a self-publisher of children’s stories. And perhaps a little bit on the 32 years I served as Executive Director for Keep Fremont Beautiful and the wonderful people who are sharing this adventure.
I ran an extension cord out of the garage, along the deck and then under the deck, up the trunk of the tree, around a branch and over to the chandelier. I plugged in the string of Christmas lights and TA DA… the chandelier was beautiful!
The chandelier gave off a warm glow with just enough light to keep you from falling over flower pots and other garden obstacles. The light wasn’t so bright as to attract bugs, so guests could sit and visit into the night without bother.
I plugged in the chandelier on special occasions – only when we were planning on sitting on the deck. The chandelier had a rather long and happy life. Eventually the strand of light went dark. Then the task of untangling the lights and beads began. I have to admit that making the chandelier was more fun than taking it apart.
Since that first chandelier, I have made several more. I have used and re-used the beads from the beaded curtains and lately I have utilized old strands of Christmas beads. I buy the wire hanging baskets, use them one year and then throw away the liner and turn it into a chandelier the next year.
I now have three chandeliers hanging in the trees by the deck in the backyard. I sort of ran out of things to repurpose so I buy glass Christmas bangles, dangles and beaded decorations after Christmas or during the pre-Christmas sales. I have a stash of pretties in my closet that I can pull out when the “New Chandelier” urge strikes.
My niece Darci has admired my chandeliers and has asked me to make her one. I don’t do that! But I did invite her to come over and make one for herself. I found an old wire basket in the garage and retrieved the stash of baubles from the closet.
I’ve been doing this chandelier thing for many years now. Assembling, enjoying, disassembling and repeat. I’m not going to claim I’m an expert at making garden chandeliers… but I have designed a rather clever chandelier work station. The work station isn’t elaborate - just a hook in the ceiling and a hanger.
The hook hangs over the couch in the living room. The wire coat hanger hangs from the hook. The wire basket hangs from the end of the hanger. All of my supplies such as scissors, wire cutters, wire, zip ties, Christmas lights, baubles, bangles, dangles and beads are lined up on the couch.
I can easily reach most parts of the hanging basket. I do keep a little step stool handy for those instances when I need to attach lights, beads or baubles at the very tip top - where the three basket chains meet at the hook.
So anyway, I prepped the chandelier making station, filling it with assorted bling and necessary equipment. When Darci arrived, the basket was hung and awaiting her creativity. I did give her a few directions and showed her how I start. First the beads and lights – then the baubles.
Unfortunately, or fortunately – depending on how you look at it – Darci doesn’t have an outside outlet at her house, so she ordered a strand of solar lights – which she added to the chandelier later. And I must say, when she sent me a picture of the finished product, the lights looked lovely. So – if you don’t have an outside outlet, not to worry – solar lights look fantastic and work great.
Oma Sue loves her chandeliers. Oma loves chandeliers here! Oma loves chandeliers there! Oma loves chandeliers everywhere… in the garden, by the deck, in front of the shed, what the heck! Hanging from the trees, by the back door, under the eaves, even shining through the leaves, Oma Loves Chandeliers if you please… hmmph… must have been having an Oma “Seuss” moment there.
If you have read this far, please don’t throw your old wire basket or beaded curtain away! I will gladly take those items off your hands and reuse them to make another chandelier. You just can’t have enough garden chandeliers!

domain: hobby


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UCT Summer School 2017
If there’s one word linking all the Summer School 2017 courses, it is ‘humanity’. From the wonders of the human cell to human skin, the human heart and human origins, Summer School will lay bare the science of humanity.
Human problems, too, become the focus: Why are South Africans obese? What will happen to Cape Town as a result of climate change? Why has gang culture come to dominate our communities? What is the fate of the SABC? How does smoking (of any kind) affect us?
There are courses on Shakespearean comedy, modern African literature and the origins of our massive vocabulary. The memorable novels of JRR Tolkien and CS Lewis provide a feast of fantasy, along with the mysteries of Eleusis and the tradition of pilgrimage. Art features strongly, as always, with popular lecturers returning to discuss contemporary artists from Jackson Pollock to Marina Abramović, as well as art nouveau, the Medici and the art and architecture of Vienna.
Human skill has brought us astronomy, archaeology, medicine and music, but human emotions and differences have also brought war, conflict, prejudice and inhumanity, themes covered in a variety of courses on World War I, the Crimea, the Bolshevik revolution, decolonial thought, negative emotions and antisemitism.
It’s important, then, that Summer School is able to bring Mary Burton to lecture on reconciliation and Judges Davis, Moseneke and Yacoob to ponder twenty years of constitutionalism. To guide participants symbolically through all this content, there is a course on lighthouses.
To read more about individual courses, see news about Summer School lecturers or download the 2017 brochure, visit http://www.summerschool.uct.ac.za/
Summer School is a flagship programme of UCT's public education-oriented Centre for Extra-Mural Studies (EMS). It offers the wider public, regardless of educational qualifications, a taste of the range of academic expertise available through UCT. In addition, it brings to Cape Town world-class lecturers in a variety of disciplines. It is the only summer school in Africa, drawing people not only from other parts of the continent, but from as far afield as Canada and Switzerland.
The annual Summer School programme aims to do the following, through a range of short courses:
- Make recent university research available to the general public
- Provide a range of study options drawing on different disciplines
- Stimulate debate about important issues
- Encourage a diverse community of students to enjoy adult study
All courses are for non-degree purposes and involve no examinations. For more information about what is on offer visit the Summer School website.
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domain: artistic


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Alignment of vascular endothelial cells (ECs) in the direction of the flow is considered a key factor in maintaining endothelial integrity in an active hemodynamic environment. Our recent studies showed that exposure to oxidized LDL (oxLDL), one of the major proatherogenic lipoproteins, significantly increases the stiffness of human aortic ECs, suggesting that oxLDL may have a significant impact on the sensitivity of ECs to mechanical stimuli. In this study, we show that oxLDL strongly enhances the ability of ECs to realign in the direction of the flow and facilitates the formation of F-actin stress fibers under static and flow conditions. The impact of oxLDL on the flow-induced realignment is observed on whole cell and single-fiber levels. We also show that, similar to the effect of oxLDL on endothelial stiffness, the impact of oxLDL on flow-induced realignment can be simulated by methyl-β-cyclodextrin-induced cholesterol depletion, supporting the hypothesis that oxLDL acts as cholesterol acceptor, rather than cholesterol donor, for ECs. Finally, we propose that oxLDL/cholesterol depletion-induced sensitization of ECs to flow may be a result of an increase in cellular stiffness and a respective increase in membrane-cytoskeleton tension.
- lipid rafts
hemodynamic forces generated by blood flow are known to play prominent roles in the acute control of vascular tone, regulation of arterial structure, and localization of atherosclerotic lesions (12, 19, 31). The primary tissue that is affected by the hemodynamic environment is vascular endothelium, a single-cell layer that constitutes the inner lining of the blood vessels and exists on the blood-vascular wall interface. Multiple studies have shown that endothelial cells (ECs) respond to flow by a variety of mechanisms, including cytoskeleton rearrangement, activation of multiple signaling pathways, and changes in gene expression (for review see Refs. 9–11, 24, 25, 34). Although the exact mechanisms responsible for conversion of mechanical stimuli to the biological responses are not fully understood, it is generally accepted that the cytoskeleton provides the structural framework for transmission of mechanical signals throughout the cell. Flow-induced changes of endothelial morphology, such as realignment in the direction of flow and cell elongation, are suggested to be important for maintaining endothelial integrity in active flow environments (9, 20, 25).
Our recent studies showed that endothelial mechanical properties are strongly affected by exposure of cells to the oxidized form of low-density lipoproteins (oxLDL) (6). More specifically, exposure to oxLDL, but not the unoxidized form of LDL, resulted in a significant decrease in the deformability/increase in stiffness of aortic ECs, as measured by micropipette aspiration (microaspiration), as well as an increase in the ability of ECs to generate force on the cell-substrate interface (6). Depletion of cellular cholesterol had the same effect (6) and also increased membrane-cytoskeleton adhesion (37). Multiple studies have shown that deformability of the cellular envelope, a two-component system consisting of a membrane lipid bilayer and the underlying submembrane cytoskeleton, depends more on the properties of the cytoskeleton than on the physical properties of the lipid bilayer (29, 32, 35). Consistent with these studies, we previously showed that an increase in endothelial stiffness critically depends on the integrity of F-actin (4). In the present study, we show that an oxLDL-induced increase in endothelial stiffness is accompanied by an increased ability of ECs to realign in the direction of the flow. Similar to our earlier studies, methyl-β-cyclodextrin (MβCD)-induced depletion of cellular cholesterol has the same effects as exposure to oxLDL. We propose that an oxLDL-induced increase in endothelial stiffness may sensitize the cells to a mechanical stimulus generated by shear stress.
Cells and reagents.
Human aortic ECs (HAECs) between passages 3 and 6 were grown in EC growth medium (EGM-2, Clonetics, San Diego, CA) supplemented with 2% FBS. Bovine aortic ECs (BAECs) between passages 5 and 15 were grown in DMEM (Cell Grow, Washington, DC) supplemented with 10% FBS. Cell cultures were maintained in a humidified incubator at 37°C with 5% CO2. Cells were fed and split every 3–4 days. oxLDL (Biomedical Technologies, Stoughton, MA) was dissolved in EGM-2 supplemented with 0.2% FBS. MβCD (Sigma Chemical, St. Louis, MO) was also dissolved in 0.2% FBS-EGM-2.
Microaspiration of substrate-attached ECs was performed as described in our earlier study (4). Briefly, the membranes were visualized with the fluorescent membrane dye carbocyanide DiIC18 (Molecular Probes) and then aspirated using micropipettes (3–5 μm OD) pulled from borosilicate glass capillaries (SG10 glass, Richland Glass, Richland, NJ). Negative pressure was applied to a pipette by a pneumatic transducer tester (BioTek Instruments, Winooski, VT).
HAECs or BAECs were seeded at a density of 1.7 × 105/cm2 on gelatin- or collagen IV-coated slides and placed in a parallel-plate chamber connected to a recirculating flow circuit composed of a variable-speed peristaltic pump, a fluid capacitor that damped pulsation, and a reservoir with culture medium. The flow chamber consisted of a Teflon upper plate and a stainless steel bottom plate held together by eight screws. A medical-grade silicon gasket was used to seal the chamber and prevent fluid leakage. A precisely machined recess (1 × 30 × 120 mm) on the top plate defined the flow path in the chamber. The top plate also provided inlet and outlet ports and a quartz window for light transmission and sample visualization. Alternatively, in some experiments, cells were mounted onto disposable parallel-plate flow chambers with a 0.4 × 3.8 × 17 mm flow chamber (μ-slides VI, Ibidi, Integrated Biodiagnostic, Munich, Germany). No difference was observed between the experiments performed using the two types of flow chambers. In both cases, the temperature of the fluid in the reservoir is maintained constant at 37°C by immersion of the reservoir into a water bath. The level of CO2 is maintained by bubbling the gas into the fluid. The wall shear stress (τ) is calculated as follows: τ = 6μQ̇/wh2 (2), where μ is fluid viscosity (0.007 g·cm−1·s−1 for PBS), Q̇ is flow rate (ml/s), w is width of the chamber (cm), and h is height of the chamber (cm).
Imaging and analysis of cell alignment.
Images were acquired using an inverted microscope (Eclipse TE2000-U, Nikon) with a CoolSnap camera (Photometrix). Cell alignment in the direction of flow was determined by measurement of the angle between the long axis of the cell determined visually and the direction of flow using MetaVue 6.2R6 software (Molecular Devices). Cells that are aligned perfectly in the direction of the flow have an angle of 0°, and cells that are perpendicular to the direction of the flow have an angle of 90°. The full range of angles varies between −90° and 90°. When cells are not aligned, the distribution is expected to be random, whereas flow-induced alignment is expected to narrow the distribution, generating a peak coinciding with the direction of flow. Cell elongation was estimated as the ratio of cell length to cell width. Since most subconfluent cells have a clear elongated shape, the long axis was determined visually. Statistical analysis for narrowing orientation distributions was performed using a standard F-test to compare the variances of the two data sets and a standard two-sample Student's t-test, with the assumption that variances of the two data sets for cell elongation ratios are unequal. Statistical significance was set at 5% (P < 0.05).
F-actin staining was performed using a standard procedure. Briefly, cells were fixed in 4% paraformaldehyde for 20 min, permeablized with 0.1% Triton X-100 for 5 min, and incubated with 0.1 μM rhodamine-phalloidin (Sigma Chemical) for 40 min. The images were acquired using a three-dimensional (3-D) deconvolution microscope (Axiovert 100TV, Zeiss) with a ×63 plan-apochromat lens (NA 1.4), a precisely controlled xyz stage (Applied Precision, Issaquah, WA), and a scientific-grade cooled charge-coupled device camera (MicroMax, Princeton Instruments, Trenton, NJ). For creation of 3-D reconstructions of the cells, 20 optical sections, 300 nm apart along the z-axis, were obtained from each cell. Constrained iterative deconvolution and 3-D rendering were performed using Deltavision software (Softworx, Applied Precision) on a reduced instruction set computer (RISC) workstation (model 02 R10000, Silicon Graphics, Mountain View, CA).
oxLDL enhances flow-induced realignment of HAECs.
HAECs were preexposed to 10 μg/ml oxLDL (oxidation state 10–15 nmol/mg protein TBAR) for 1 h, as described in previous studies (3, 6). The levels of oxLDL were chosen to simulate the levels of circulating oxLDL reported in human plasma (22) and plasma of hypercholesterolemic animals (21). Control cells were exposed to the low (0.2%) serum alone for the same duration. After exposure to oxLDL, cells were mounted onto a flow apparatus and exposed to shear stress of 10 dyn/cm2 for 12 h, similar to the physiological levels of shear stress in human arteries (13). During the flow, cells were exposed to normal (2%) serum. All experiments were performed with subconfluent endothelial cultures to allow a direct comparison between sensitivity of the cells to flow and cell stiffness estimated by microaspiration, a technique that requires single cells. As shown in our earlier study (6), exposure to oxLDL significantly decreases the deformability of the cells, estimated by pulling the membrane into a micropipette (Fig. 1, inset). As expected, before exposure to flow (0 h), neither control nor oxLDL-treated cells have a preferential orientation relative to the direction of the flow (Fig. 1). Control HAECs appear to be relatively resistant to flow-induced realignment, with no significant decrease in standard deviations of the angles after 12 h of flow (Fig. 1). Exposure to oxLDL, however, dramatically enhanced flow-induced realignment of HAECs (Fig. 1). More specifically, oxLDL-treated cells showed pronounced realignment in the direction of the flow after 3 h of flow exposure, as evidenced by a decrease in standard deviations of cell orientation angles. Further realignment was observed after 6 and 12 h. A lack of flow realignment of control HAECs underscores the impact of oxLDL on the ability of these cells to sense and/or respond to flow by reorientating themselves in the direction of the flow. oxLDL also enhanced flow-induced cell elongation (Fig. 2).
OxLDL enhances alignment of F-actin stress fibers.
Earlier studies showed that oxLDL induces polymerization of actin and formation of F-actin stress fibers in several cell types (14, 26–28), including HAECs (14). Consistent with these studies, Fig. 3 shows that oxLDL also induces actin polymerization in HAECs. Under control no-flow conditions, HAECs have typical endothelial morphology, with a network of thin F-actin filaments (Fig. 3A). Exposure to oxLDL does not change the morphology of the cells but induces a marked increase in F-actin polymerization: F-actin-specific fluorescence increased from 37.7 ± 1.4 to 46.1 ± 1.8 (P < 0.05). Cells also have prominent stress fibers that crisscross the cytosolic regions (Fig. 3B). As expected (25, 34), exposure of the cells to flow induces formation of the stress fibers in control and oxLDL-treated cells (Fig. 3, C and D): F-actin specific fluorescence was 63.3 ± 6.5 and 92.2 ± 10.4 (P < 0.05) in control and oxLDL-treated cells, respectively. To analyze further the organization of F-actin in control and oxLDL-treated cells, we measured the angles of individual stress fibers in cells selected randomly from the two cell populations after the cells were exposed to flow for 6 h (30–40 individual fibers, which could be clearly identified and generally represented the brightest ones, were analyzed in each cell; curved fibers were excluded from the analysis). The angles were determined relative to the direction of the flow. This analysis shows that, consistent with the changes in cell orientations, exposure to oxLDL also significantly decreased the spread of the orientation angles and facilitated the realignment of the fibers in the direction of the flow (Fig. 3, E and F).
Cholesterol depletion enhances flow-induced realignment of HAECs.
Earlier studies showed that exposure to oxLDL results in cholesterol depletion of caveolae in vascular ECs and in homogenates of murine blood vessels (3, 23). Consistent with the notion that oxLDL induces cholesterol depletion from endothelial caveolae, we previously showed that oxLDL-induced endothelial stiffening can be simulated by MβCD-induced cholesterol depletion (6). Here we show that MβCD-induced endothelial stiffening (Fig. 4, inset) is accompanied by the facilitation of the ability of HAECs to realign in the direction of the flow (Fig. 4, A and B). The kinetics of the effect was slightly different than that of oxLDL in a sense that no significant effect was observed after 3 h of flow, but at 6 and 12 h the effects of MβCD and oxLDL were similar. As described in our earlier study using BAECs (4), MβCD-induced cholesterol depletion has no apparent effect on the degree of actin polymerization under static conditions (Fig. 5, A and B), but after the flow exposure, prominent stress fibers formed in control and MβCD-treated cells (Fig. 5, C and D). Similar to oxLDL, cholesterol depletion also significantly decreased the spread of individual actin fiber orientation (Fig. 5E).
oxLDL-induced enhancement of endothelial realignment in not unique to HAECs.
As pointed out above, HAECs are relatively resistant to flow-induced realignment. A question arises, therefore: is the effect of oxLDL on flow-induced realignment unique to HAECs precisely because of their inability to realign efficiently under normal-cholesterol conditions? To address this question, we tested whether oxLDL has a similar effect on BAECs, which are known to realign very well and have been used as a model for endothelial realignment in multiple earlier studies. Figure 6 shows that, similar to HAECs, exposure to oxLDL (10 μg/ml, 1 h) also enhances flow-induced realignment of BAECs. It is also interesting to note that we showed previously that BAECs are significantly stiffer than HAECs, as measured by microaspiration (5), an observation consistent with our hypothesis that an increase in cell stiffness is associated with an increased sensitivity of ECs to flow-induced realignment.
oxLDL-induced effect on endothelial realignment is partially reversed by acetylated LDL.
Earlier studies showed that oxLDL and acetylated LDL (acLDL) have the opposite effects on the level of endothelial cholesterol: oxLDL depleted cholesterol from endothelial caveolae (3), and acLDL enriched ECs with cholesterol (15). Indeed, acLDL is a known cholesterol donor and is widely used in lipoprotein research to load cells with cholesterol and simulate the physiological effects of LDL (16, 30). Furthermore, we showed earlier that exposure of aortic ECs to 50 μg/ml acLDL for 24 h increases endothelial cholesterol approximately twofold, similar to the increase observed in vivo under hypercholesterolemic conditions (15). Therefore, we tested whether the effect of oxLDL may be reversed by acLDL. In this series of experiments, cells were exposed to oxLDL (10 μg/ml), acLDL (50 μg/ml), or oxLDL + acLDL for 24 h. As shown in Fig. 7, the oxLDL-induced effect on flow-induced realignment was reversed by the simultaneous exposure to acLDL, supporting our hypothesis that changes in membrane cholesterol play a key role in the observed effects.
A hallmark of the endothelial response to flow is EC realignment in the direction of the flow. The realignment is believed to be important in distributing the hemodynamic forces applied to the luminal surface of the cells to the attachment sites on the basement membrane and, thus, preventing endothelial detachment, which would jeopardize the integrity of the endothelial layer (17, 41). It was also suggested that alignment of ECs in the direction of the flow reduces the shear gradients on the luminal cell surface, which also is expected to have a protective effect under high-shear conditions (1). Our study shows that EC realignment in the direction of the flow is enhanced when cells are preexposed to oxLDL.
Multiple studies have shown that flow-induced EC realignment is accompanied by the formation of thick bundles of F-actin filaments containing myosin and α-actinin, also known as F-actin stress fibers (25, 34). Furthermore, although F-actin stress fibers are found in a variety of cell types when cultured in vitro, this structure appears to be unique to vascular ECs in vivo (41). The most pronounced fibers oriented in the direction of the flow are observed in regions exposed to high-velocity flow, such as the left ventricle and aorta (41). Typically, flow-induced generation of the stress fibers occurs before EC realignment in the direction of the flow, and the fibers can be randomly distributed or oriented along the long axis of the cells (17, 25, 34). It is also known that the integrity of F-actin fibers is essential for flow-induced EC realignment (25, 34, 40). In the present study, we investigated how acute exposure to oxLDL alters the organization of F-actin in ECs exposed to steady unidirectional laminar flow. First, we show that oxLDL enhances F-actin polymerization in cells maintained under static conditions and in cells exposed to flow. These observations are in agreement with earlier studies showing that acute exposure to oxLDL induces formation of F-actin stress fibers, increases endothelial contractility (14), and induces activation of RhoA (14, 18, 36), which is well known to induce stress fiber formation. A longer (24 h) exposure to oxLDL resulted in disappearance of individual stress fibers and clustering of F-actin in the peripheral regions of the cells (43). Formation of actin stress fibers and formation of peripheral an actin band were suggested to contribute to an increase in endothelial permeability (14, 43). oxLDL was also reported to induce actin polymerization in macrophages (26, 27). In the present study, we extended these observations further to show that oxLDL also facilitates the reorientation of actin fibers in the direction of the flow, demonstrating that enhancement of flow-induced realignment of aortic ECs occurs on whole cell and individual fiber levels. Further studies are needed to determine the impact of oxLDL on the sensitivity of ECs to disturbed flow characteristic to atheroprone regions.
In terms of the mechanism, we propose that the effect of oxLDL is mediated by changes in the cholesterol content of the membrane. Several lines of evidence support this hypothesis. Earlier studies showed that oxLDL induces depletion of cholesterol from the caveolae followed by the internalization of caveolin (3). In addition, we recently showed that oxLDL also induces internalization of another major lipid raft marker, GM1, and that this effect is simulated by MβCD-induced cholesterol depletion (6). Consistent with these observations, we show here that oxLDL-induced facilitation of endothelial realignment is also simulated by cholesterol depletion. It is noteworthy, however, that oxLDL-induced enhancement of endothelial realignment is observed earlier than the effect of MβCD-induced cholesterol depletion, suggesting that cholesterol depletion may not fully account for the effect of oxLDL. Alternatively, it is also possible that oxLDL is more specific and efficient than MβCD in removing cholesterol from a specific membrane compartment, such as caveolae, whereas MβCD may not only decrease cholesterol in all membrane domains but may also induce redistribution of cholesterol from one membrane domain to another (44). Finally, we show here that oxLDL-induced enhancement of endothelial realignment is rescued by exposure of the cells to acLDL, whereas exposure to acLDL alone has no significant effect. The latter observation is also consistent with our previous study showing that cholesterol enrichment has no impact of endothelial stiffness (4).
What is the possible link between oxLDL/cholesterol depletion and the sensitization of cells to flow? Our recent studies showed that oxLDL and MβCD result in an increase in stiffness of vascular ECs (4–6), and we propose that changes in endothelial biomechanics play a critical role in the sensitization of the cells of flow. Indeed, formation of stress fibers is expected to increase cell stiffness, consistent with the earlier studies showing that shear stress alone also induces an increase in cell stiffness (33, 34). An increase in stress fiber content and an associated increase in cell stiffness are expected to result in an increase in cortical tension that develops in the submembrane cortical region of the cytoskeleton. Our general hypothesis is that oxLDL-induced endothelial stiffening increases cortical cytoskeleton tension and results in sensitization of the cells to a mechanical signal generated by shear stress (Fig. 8). The exact nature of the flow sensor, however, is not known, despite the numerous studies addressing this question. The putative candidates for flow sensors include integrins, ion channels, G proteins (12, 25), and, more recently the endothelial glycocalyx (42). The latter appears to be in apparent contradiction with our studies, because diet-induced dyslipidemia, in general, and oxLDL, in particular, were shown to result in partial degradation of the endothelial glycocalyx (7, 38, 39). oxLDL-induced degradation of the glycocalyx, however, appears to be transient, with full recovery after ∼1 h (7, 39) and, therefore, may not have a major impact on flow-induced endothelial realignment. Further studies are needed to elucidate specific molecular pathways responsible for oxLDL-induced endothelial stiffening and flow sensitization.
Finally, several lines of evidence suggest that oxLDL-induced endothelial stiffening may occur in vivo. Cholesterol depletion of endothelial caveolae is observed not only in response to oxLDL in vitro, but also under dyslipidemic conditions in vivo. Specifically, cholesterol content is lower in caveolae isolated from the vessels of cholesterol-fed apolipoprotein E-deficient mice, a mouse model for atherosclerosis, than in caveolae isolated from control animals (23). Furthermore, ECs covering fatty streaks in the vessels of cholesterol-fed rabbits were shown to have fewer caveolae, an effect that was also simulated by cholesterol depletion in cultured ECs (8). Consistent with these studies, we previously showed that dyslipidemia also results in an increase in endothelial stiffness in a diet-induced porcine model of atherosclerosis (6). We propose, therefore, that oxLDL-induced changes in endothelial biomechanics play an important role in endothelial physiology in vivo.
This work was supported by National Heart, Lung, and Blood Institute Grants HL-073965 and HL-083298.
We thank Dr. Peter Davies for sharing with us the flow apparatus and for multiple discussions throughout this project. We also thank Mete Civelek for help in the initial stages of the experiments and Dr. Min Joo for help with the statistical analysis of the variances.
The costs of publication of this article were defrayed in part by the payment of page charges. The article must therefore be hereby marked “advertisement” in accordance with 18 U.S.C. Section 1734 solely to indicate this fact.
- Copyright © 2008 the American Physiological Society

domain: literature


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Welcome, Welcome to another exciting episode of Capes & Scowls West! We’re back from our hiatus with a bunch of great content. And coincidently it is Episode #42 – the meaning of life, the universe and everything! This episode we’ve got a ton of news to get through, Including the reinstatement of James Gunn. And to wrap up, we will […]Continue reading »
Welcome Everybody to another exciting episode of Capes & Scowls West! We’ve got a lot of exciting content coming at you in 2019, and this is one of the first in a long line. Here is our first reviews episode of the new year, and it’s a doozy! This week we review Middlewest #2 & #3 as well as Batman […]Continue reading »
Hey there Everyone! It’s our November 30th reviews episode. we have an entierly new format of our reviews show, and we’re really excited about it. In our reviews episode, we will only be doing long form reviews of a three or four comics. Our one hits (the ones that we tended to drone on about), will now be in video […]Continue reading »
Tim breaks down his picks for this years Eisner Awards that take place from SDCC in July! The CAS crew let you know the who and the why of the biggest awards show in comics. Enjoy!

domain: entertainment


In recent years, the adoption of electric vehicles (EVs) has gained significant momentum, driven by the increasing awareness of environmental sustainability and the need to reduce carbon emissions. As a result, the demand for efficient and convenient EV charging solutions has become more pressing than ever. Australia, with its vast landscapes and long distances between cities, poses unique challenges for the widespread adoption of EVs. However, the country has been at the forefront of embracing innovative technologies to maximise convenience and efficiency in EV charging.
This blog post explores the latest advancements in EV charging technology in Australia, highlighting the transformative solutions that are revolutionising the way we charge our electric vehicles. From ultra-fast charging stations to smart grid integration, these innovations are poised to accelerate the transition towards a cleaner and more sustainable transportation future.
The Latest Innovations in EV Charging Technology To maximise Efficiency and Efficiency
Australia has been at the forefront of embracing innovative technologies to maximise convenience and efficiency in EV charging. In this article,we will be delving into the latest advancements in EV charging technology, highlighting the transformative solutions that are revolutionising the way we charge our electric vehicles. Additionally, we will explore the importance of engaging EV charger installation experts to ensure a seamless and effective charging infrastructure rollout.
1. Ultra-Fast Charging Stations
One of the most significant innovations in EV charging technology is the advent of ultra-fast charging stations. These stations utilise high-powered charging infrastructure capable of delivering charging speeds of up to 350 kilowatts (kW). The advancements in battery technology, combined with higher charging capacities, have significantly reduced the charging time for EVs. For instance, with a 350 kW charging station, an EV can be charged from 0 to 80% in under 30 minutes, making long-distance travel more viable and convenient. Ultra-fast charging stations are being strategically deployed across major highways and city centres in Australia, providing EV owners with the confidence to embark on long journeys without worrying about extensive charging delays.
2. Bidirectional Charging and Vehicle-to-Grid Integration
Bidirectional charging and vehicle-to-grid (V2G) integration are groundbreaking innovations that enable EVs to not only draw energy from the grid but also supply excess energy back to it. This technology transforms EVs into mobile energy storage systems, effectively turning them into valuable assets for grid stability and energy management. By utilising bidirectional charging and V2G capabilities, EV owners can contribute to balancing the grid during peak demand periods or sell stored energy back to the grid for financial incentives. This integration has the potential to create a more resilient and sustainable energy ecosystem while maximising the convenience and efficiency of EV charging.
3. Smart Grid Integration and Demand Response
To further optimise EV charging infrastructure, smart grid integration and demand response mechanisms are being implemented. Smart grids use advanced communication and control systems to manage the flow of electricity, ensuring efficient and reliable charging for EVs. By integrating EV charging with the smart grid, charging patterns can be analysed, and energy demand can be forecasted, leading to more accurate load balancing and grid optimization. Additionally, demand response programs encourage EV owners to charge their vehicles during off-peak hours, incentivizing flexible charging behaviour and reducing strain on the grid during peak demand periods. Collaborations between EV charging providers, utility companies, and grid operators are crucial in deploying effective smart grid integration strategies.
4. Wireless Charging Technology
Wireless charging technology has made significant strides in recent years, presenting a promising solution to enhance the convenience and user experience of EV charging. Wireless charging eliminates the need for physical connections between the charging infrastructure and the EV, allowing for a seamless and effortless charging process. By utilising magnetic induction or resonant coupling, wireless chargers transfer energy wirelessly to the vehicle’s receiving pad. The convenience of wireless charging is particularly beneficial for public charging stations and workplaces, where users can simply park their vehicles over the charging pad without the hassle of physically plugging in cables. Though still in the early stages of deployment, wireless charging technology is set to revolutionise the EV charging landscape, further maximising convenience and efficiency.
5. Importance of EV Charger Installation Experts
As the demand for EV charging infrastructure continues to surge, the expertise of EV charger installation professionals becomes increasingly crucial. These experts possess the knowledge and experience necessary to design and deploy charging systems that meet the specific needs of different locations and users. They can assess the power requirements, conduct site surveys, ensure compliance with safety regulations, and manage the installation process efficiently. Engaging EV charger installation experts helps streamline the implementation of charging infrastructure, reducing installation costs, and ensuring optimal performance and reliability.
To sum it up,, the latest innovations in EV charging technology are transforming the landscape of electric vehicle adoption by maximising convenience and efficiency. From ultra-fast charging stations that drastically reduce charging times to bidirectional charging and vehicle-to-grid integration that turn EVs into valuable assets for grid stability, these advancements are propelling the transition towards a cleaner and greener transportation future. Smart grid integration and demand response mechanisms optimise charging patterns and reduce strain on the grid, while wireless charging technology offers seamless and effortless charging experiences. Engaging the expertise of EV charger installation professionals ensures the smooth deployment of charging infrastructure, further enhancing the overall efficiency and reliability of EV charging. With these groundbreaking technologies and collaborative efforts, we are well on our way to realising a sustainable and accessible EV charging ecosystem that will accelerate the global shift towards a more environmentally friendly transportation system.


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Encroachers on a university land in Nairobi’s Upper Hill area have been given two weeks to vacate the area or be forcibly evicted. Lands Cabinet secretary Charity Ngilu yesterday led ministry officials to the contested 1.6 hectares of land on Chyulu Road off Ngong Road and gave marching orders to the traders.
The CS said the land which is opposite Nairobi Sports Club and next to Meladen hotel is legally owned by the South Eastern Kenya University and the traders illegally encroached on the piece of land. She dismissed as null and void the traders “ownership documents” which she said did not originate from the ministry.
Ngilu said the land according to Land ministry’s records was registered under Ukambani Agricultural Institute which was later upgraded to South Eastern Kenya University.
University Vice-Chancellor Geoffrey Muluvi lauded the move by the Lands ministry saying the university had petitioned the ministry in the past with little success. In the past month, the ministry has been tough on grabbers of public land especially in Nairobi where many structures have been demolished by the ministry. Schools, road reserves and water projects have been the major casualties of the land grabbing in the country.
Would you like to get published on this Popular Blog? You can now email Cyprian Nyakundi any breaking news, Exposes, story ideas, human interest articles or interesting videos on: [email protected] Videos and pictures can be sent to +254 710 280 973 on WhatsApp, Signal and Telegram.

domain: news


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(CNN) - In an opinion piece published Thursday evening, the presumed GOP presidential candidate touted lessons gleaned during his time heading the private equity firm Bain Capital as having prepared him to handle the presidency.
"The lessons I learned over my 15 years at Bain Capital were valuable in helping me turn around the 2002 Winter Olympics in Salt Lake City," he wrote in the op-ed, which was published to the website of The Wall Street Journal.
(CNN) - Want to know what the Republican vice presidential candidate really thinks of President Barack Obama?
Just ask Rep. Paul Ryan to play word association.
(CNN) - High-profile pastor Rick Warren has called off plans for a presidential forum that he said was scheduled to include both major party candidates, but there are conflicting accounts about why the event was canceled.
Warren told the Orange County Register that he was nixing his "civil forum" because of the toxic political climate.FULL STORY
(CNN) - While the campaign did not deny the restriction was given, a spokesman for Mitt Romney's presidential campaign pushed back Thursday against a report that a television reporter was instructed not to ask Romney certain questions in an interview.
In response to the charge, a Romney campaign official told CNN, "This is not how we operate. The matter is being addressed."
(CNN) - Vice President Joe Biden will visit one of the wealthiest ZIP codes in the nation, and mingle with rich and famous, on Friday to raise campaign cash.
The vice president will attend two fund-raisers in Bridgehampton, one of the tony enclaves in the Hamptons on the East End of New York's Long Island, CNN confirmed.
Washington (CNN) –U.S. Capitol Police and the FBI are investigating a reported threat against Rep. Todd Akin, a police spokeswoman said Thursday.
There is "an active, open investigation, Lt. Kimberly Schneider said, without revealing further details, citing a policy against discussing the security of members of Congress.
(CNN) - Earlier this week, CNN obtained portions of the Republican Party's 2012 platform, which included language about the GOP's position on abortion.
The language will not be official until it's ratified by convention delegates next week, but it's unlikely to undergo any changes before then.
Because the abortion plank has become a source of controversy and debate in the presidential race this week, we've posted the full language here for those interested in reading the entire passage.
Fayetteville, North Carolina (CNN) - During a visit to the Fort Bragg area Thursday, vice presidential hopeful Rep. Paul Ryan said President Barack Obama needs to come up with a budget agreement or else North Carolina's defense industry and one of the nation's largest military populations will be threatened.
The House Budget Committee chairman – along with other Republicans – voted for the original debt ceiling deal that led to the current stalemate. The policy came about after a congressional "super committee" failed to reach a deficit-reduction plan last year. Months earlier, Congress had voted to implement the cuts if the super committee didn't ultimately find an agreement.
(CNN) - Texas Democrats are calling for the resignation of a Republican elected county judge who warned this week that the nation could descend into civil war if President Barack Obama is re-elected.
"It's really up to Judge (Tom) Head to do the right thing and resign and stop embarrassing Lubbock County," said Kenny Ketner, who became the county Democratic Party's chief Monday.FULL STORY
CNN's GUT CHECK | for August 23, 2012 | 5 p.m.
– n. a pause to assess the state, progress or condition of the political news cycle
BREAKING: AKIN ASSESSING CANDIDACY WITH CONSERVATIVES IN FLORIDA… Facing pressure from Republican heavyweights in Washington to abandon his Missouri Senate bid, Rep. Todd Akin is huddling with top conservative activists in Tampa to assess whether to move forward with his embattled candidacy. Akin spent Wednesday night and Thursday in a series of private meetings at the two-day summit of the Council For National Policy (CNP), a secretive group of conservative leaders who are meeting in Florida before next week’s Republican National Convention. – Peter Hamby and Mark Preston


Here, the author emphasizes that electricity is a special operation. For safety reasons, non -professionals cannot operate. The purpose of this article is to test whether the line is charged under the circumstances! However, non -licenseal personnel are prohibited from conducting power operations.
Electric pens are found by almost every family. A kind of electric pen used before, like a screwdriver, the tail will be on when the switch jack is exposed to the switch jack. When you grow up, you know that this kind of contact test pen is a relatively earlier electrical pen. Different from this kind of electrical pen is the current new type of electrical pen, the name is called hard stone induction number.
For many electrician friends, this kind of electrical pen is used more.
This new type of electric meter is a hardstone tool product, which is suitable for direct detection of the cross -current voltage of 12V to 250V, and indirectly detecting the zero, phase lines, and breakpoints of the AC electricity. Reading is intuitive, complete, and cheap.
1. button description
A key “Direct”: When the direct measuring key (far away from the LCD screen), that is, when you directly contact the line with the front end of the metal (referred to as the batch head), press this button.
B key “INDUCTANCE”: When the sensing/breakpoint measuring key (closer to the LCD screen), that is, when the batch head induction (note is induction, instead of direct contact) line, press this button.
Regardless of how the text on the pen is printed, in general, the farther away from the LCD screen is the direct measurement of health, and the sensing/breakpoint measurement key is closer to the LCD screen. If this is not the layout, it will indicate that it is a cottage or inferior product. For your safety, it is not recommended to buy it.
2. Direct detection:
1. Touch the direct measurement (Direct) key, and directly contact the detection object in the front end of the metal of the electric pen;
1.1 The final number is the measured voltage value (the voltage value of the voltage of 12V, 36V, 55V, 110V, and 220V in this test is usually ≤ 36V.
1.2 When the display value is 70%before the high paragraph, the low paragraph value is displayed;
1.3. When measuring non -ground DC electricity, touch another pole (such as positive or negative poles).
2. When the electric pen is directly exposed to the line of fire, no matter whether the hand is encountered or not, the indicator light will immediately light up:
2.1 When the hand did not encounter the Renyi measurement key, the indicator light turned on and displayed 12V. This value was not allowed;
2.2 When the sensor/breakpoint measuring key is touched by the hand, the indicator light is on and 110V is displayed. This value is not allowed;
2.3 When the hand touches the direct measurement key, the indicator lights lit and display 220V. This value is accurate;
2.4 In summary, when the hand did not encounter any measuring key, once the indicator light is on, it indicates that the fire line of AC 220V, remember!
3. When the direct measurement key is touched by the hand, when the electrical pen is directly exposed to the conductive objects such as the human body, the line, the zero line, the ground wire, the metal, and other conductive objects, the indicator may be on. At this time It shows no voltage.
4. When the induction/breakpoint measurement key is touched by the hand, there are two cases when the electric pen is directly exposed to the detection object:
4.1 The indicator light is on, and 110V is displayed, indicating that there is a line of fire of AC 220V. Remember!
4.2 The indicator light is not on, but the “high -voltage symbol” appears, please refer to 1,2 two points in “indirect detection”.
Third, indirect detection (also known as sensing detection):
1. Induction detection: The INDUCTANCE key (INDUCTANCE) key, the front end of the metal of the electrical pen is approaching (note that it is close, not the direct contact) is detected. If the display screen appears Internal communication electricity.
2. Breakpoint detection: When measuring the wire with a breakpoint, the INDUCTANCE key (INDUCTANCE) key, the front end of the metal of the electrical pen is close (note that it is close, not directly contact) the wire, or directly contact the wire that is directly contacting the wire. In the outer layer of the insulation, if the “high -voltage symbol” disappears, it is the breakpoint here.
3. Use this function to easily distinguish zero and phase lines (increase the distance between the line when measuring the side line). Detect the amplitude and leakage of the microwave.
1. Hardstone digital display electrical pens buttons do not need to press hard.
2. Do not contact the two measuring keys at the same time during testing, otherwise it will affect the sensitivity and test results.
3. The electric pen is a safe set. In order to ensure safety, you must confirm whether it works normally before use. Before home or factory use, find a charged plug or power supply to test whether the electrical pen is normal. After confirming that it is normal Other goals.
If you use a bad electric pen to measure the charger, then it is likely to shock when you don’t know.


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Fern Coppedge: New Discoveries
On view through April 18, 2021
James A. Michener Art Museum
This exhibition highlights the Michener’s recent acquisition of four winter landscapes by Pennsylvania Impressionist Fern Coppedge (1883-1951). Additionally, the public will get an in-depth look at the private life of the artist with the recent digitization of Coppedge’s scrapbooks from the Museum’s Library and Archives.
“We’re thrilled to add these vibrant paintings by Coppedge to our permanent collection and excited to share the new information we’ve uncovered about these works with visitors,” remarks Laura Turner Igoe, Ph.D., Curator of American Art at the Michener Art Museum.
To see this exhibition, visitors must purchase timed tickets in advance and follow all Museum guidelines for a safe visit: https://www.michenerartmuseum.org/alert/
Image: Fern I. Coppedge (1883-1951), Winter Landscape, n.d. Oil on canvas. 18 x 20 inches. Gift of David and Nancy Barclay.


Standing Fast #1 – New Line Cinema’s The Nativity Story and the Virgin Birth
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Fr. Angelo contends that The Nativity Story by New Line Cinema is a good Protestant film which was the intent of the film. His only question is why so many well educated Catholic movie reviewers are calling it a good *Catholic* film.
Read a Review of the Movie by Fr. Angelo Mary Geiger
- Early Review and Discussion
- Discussion of Labor Pains
- CCC 499 On the Perpetual Virginity
- John Paul II on the Perpetual Virginity
- Quoting John Paul II on Physical Integrity
- The Nativity Story Blog


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The world grows dark from within. The toll on life will be great. Mustard seed faith: this faith will be released. Are you listening? Do you hear Me? This season is a fortnight. Revival will sweep the nation. They will come to Me. My light grows bright. The loss will be great. There is little time. Follow me. Hear My voice. I love you.
Love the Lord, Jesus
Son of God
Ruler of the Ages
“..For I know that after my death you will become utterly corrupt, and turn aside from the way which I have commanded you. And evil will befall you in the latter days, because you will do evil in the sight of the Lord, to provoke Him to anger through the work of your hands.” (Deuteronomy 31:29, NKJV)


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Here’s an excerpt from a long, detailed, and inspiring story about Occupy Boston and the raid upon it, done with the usual military precision and pre-dawn cowardice. I draw your attention to one sentence, which I have put in bold letters. One by one, the militaristic police conditioning falters, breaks open. See this. Notice it is a woman who, apparently, cannot help but feel with the protestors, and how it is her male superiors who quickly haul her back into lock-step formation.
(Somehow, I am reminded of the play I saw yesterday, Lysistrata, actually not the Greek classic, but a contemporary version of it. Still the same plot, women deciding to withhold sex until the men stop their incessant, wasteful, murderous wars. Hilarious satire. All the male actors had giant, bulbous balloon dicks attached to their trousers, and their commander, costumed as a contemporary military officer, had a long skinny balloon that was pinched in the middle, so that the top half was limp.)
Thanks to occupywallst.org.
“The police did eventually come. They waited days, hoping people would stop paying attention. Like previous raids in other cities, they made their move like cowards in the pre-dawn shadows at 5AM this morning. The city used bulldozers to destroy what had been home to hundreds. At least 45 peaceful protesters were arrested while linking arms to nonviolently protect their homes and their right to free speech. When one female police officer began to cry, her male superiors yelled and berated her.
“Adding to suspicions that the Boston police and city officials sought to hide their actions from the public, police reportedly enforced a media blackout. Many officers were seen covering their badge numbers. According to Occupy Boston, “Credentialed press, citizen journalists, academic researchers, and Occupy Boston media members were repeatedly corralled and moved to surrounding areas 50 feet away or more, prohibiting many from thoroughly covering the raid.” Livestreamers, medics, and legal observers were also among those targeted and arrested.”

domain: sociology


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OneAZ State Forty Eight Credit Card
A Rewards Credit Card Inspired by Arizona
State Forty Eight is all about sharing our passion for the great state of Arizona. That’s why we partnered with OneAZ Credit Union for the exclusive Visa State Forty Eight Credit Card. This is a credit card for anyone who loves Arizona and wants a credit card that delivers solid rewards for their spending. With the OneAZ State Forty Eight Card, you earn rewards points with every purchase, and you have the freedom to redeem them however you choose.
Supporting local business is more important than ever.
State Forty Eight and OneAZ Credit Union know the importance of supporting Arizona businesses. Show your Arizona pride with the exclusive State Forty Eight Credit Card and get rewards every time you shop!
- Introductory rate: 0% Introductory APR for 12 months on the first 90 days of purchases. then APR of 17.24% - 24.00%
- Reward options: Cash back, travel, gift cards, merchandise, or charitable donations
- Bonus points: 5,000 after first purchase, double on balance transfers for 90 days
- Contactless Tap to Pay: Quick & Secure
- Fraud protection: 24/7 monitoring
- No annual fee

domain: economics


The second wave of the coronavirus pandemic in Poland and the partial lockdown introduced by the Polish government in November have had less of an impact on the paper and board industry than was initially feared.
In the worst case, incoming orders in recent months were described as unspectacular. In the best case, market participants said demand was going "through the roof.”
The winners during this pandemic include in particular companies from the corrugated board and packaging sector, while the Polish folding cartons industry has also performed quite well overall during this crisis.
Since the fourth quarter, a significant upturn has been observed in the uncoated fine paper segment. However, it was often the higher raw material and production costs and not the strong demand which prompted producers to initiate price negotiations.
Hikes have already been realised for brown corrugated case material and a mark-up has been announced for graphic papers and white lined chipboard. Another increase for kraftliner and white-top testliner also appears to be on the horizon.
Find out more in EUWID's quarterly report on the paper and board markets in Poland.
In our current issue you will find the EUWID Price Watch Poland for Q4 2020, which will be available to our e-paper and print subscribers as of 10 February.


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19 useful Chrome extensions for web designers
Google Chrome is one of the most popular browsers used by millions of people every day, including designers, web developers, and layout designers.
Today we want to share with you another interesting collection of Chrome apps (previous collection), in which we will focus on 19 of the most important extensions for web designers, layout designers and web developers.
1. Awesome Screenshot: Capture & Anno
Take screenshots of the entire page or its fragments, sign the created images, make annotations, blur sensitive data – almost all functions are done in one click!
2. Window Resizer
Scale your browser window to emulate different screen resolutions.
3. CSS Grady
Generating CSS gradients has never been easier. In addition, you will have the opportunity to get the code adapted for different browsers.
4. ColorPick Eyedropper
An eyedropper tool for web developer. Choose colors from any part of the web page.
5. Pixlr Express
Pixlr express is a modern photo editor with all the effects, overlays and frames from the popular pixlr-o-matic, only with more control. There are also many settings, stickers and a text creation tool here.
6. Pixlr Editor
Pixlr introduces a feature-rich photo editor right in your browser, no download or wait.
7. CSS Shack
CSS Shack lets you create layer styles (like any image processing software you know) and export them to a separate CSS file, or copy the code to the clipboard.
8. Balsamiq Mockups
Balsamiq Mockups for Google Drive lets you create, edit, and share quality sketches and prototypes using Drive.
The best HTML5 app for crisp sketches, prototypes, and interactive layouts.
11. What Font
A very useful extension for Google Chrome, What Font allows developers and designers to determine what fonts are used on a web page.
12. Web Developer
The Web Developer extension adds a button to the browser control panel that you can use to take advantage of various web development tools. This is the official copy of the Web Developer extension for Firefox.
13. BuiltWith Technology Profiler
The BuiltWith Chrome extension lets you determine how a website was designed. All you need to do is click on the builtwith icon.
Sight is a code highlighting Chrome extension that makes viewing source code in a browser a fun experience. You can choose a template, font, and include line numbering. To get a specific code, enter # ft =[syntax] next to the url file.
Stylebot allows you to quickly change the look of any website (with custom CSS).
16. Google Font Previewer
This extension allows you to select a font from the Google Font directory using several text styling options, as well as preview the selected font right in the open tab.
CSSViewer is a simple CSS property viewer for Google Chrome that was originally developed by Nicolas Huon and was provided as an add-on for FireFox.
18.Web Developer checklist
This tool allows you to check everything: whether your pages are SEO friendly, usability, and their visibility and performance (page load speed).
19. Chrome Flags
This extension is a ported version of FlagFox for Chrome. It displays a country flag that indicates the location of the sites you visit.

domain: design


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Your Bird can be the Next "Tony Hawk"
The Winger Skateboard is one of Mango's newest Bird Trick Training Skateboards. This wonderful acrylic bird skateboard lets you be the coach while your bird learns to skateboard. Your bird will be "stoked" (happy) and you will be the "sickest" (coolest) coach ever.
Both my Cockatoo Marshmellow and my Amazon Kiwi just love to watch me pull them along. We are even thinking of making Kiwi a ramp because he just seems to love the speed!
Check out the video below of Kiwi demonstrating his need for speed on Animal Planet's "Your Pet Wants This, Too"
Balanced for safety and manufactured for fun!!!
Winger Trick Training Bird Skateboard by Mango measures 12" L x 5" W x 4" H, Perch diameter measures 3/4" and is 7" L. Comes with a 24" pull chain.
Ideal trick training bird skateboard for Amazon Parrots, African Grey Parrots, Eclectus Parrots, Cockatoos, Macaws and...all similar sized birds.
If you don't have a Clicker for Training you can add a Clicker for $4.99. See option below and let the fun begin!

domain: pet


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The South Carolina women’s basketball team earned its shot at redemption Saturday after defeating Ole Miss 80-51 in its SEC tournament semifinal.
The Gamecocks dominated the Rebels from start to finish to clinch the team’s fourth consecutive championship game appearance after losing to Kentucky in last season's championship game and winning the SEC in both 2020 and 2021.
Unlike the team’s previous matchup against Ole Miss this season, which South Carolina won in overtime, this game was never close. The Gamecocks outscored the Rebels every quarter, growing its lead from start to finish.
Five South Carolina players scored in double-figures, and senior forward Laeticia Amihere’s 17 points led the team. She shot 7-10 from the floor and added six rebounds, seven assists and three blocks to her stat line.
“L.A.’s been locked in,” head coach Dawn Staley said. “I think she sees the end of it.”
Senior forward Aliyah Boston recorded her 80th career double-double with 10 points and 11 rebounds. Boston now holds the school’s all-time record with 1,432 rebounds, surpassing Sheila Foster's 1,427 rebounds from 1979 to 1982.
Junior center Kamilla Cardoso led the team in rebounds with 12 and also recorded a double-double, scoring 12 points.
“Being able to rely on anybody and call on anybody at any given moment, is a great asset to have," Amihere said.
The Gamecocks overpowered inside, scoring 54 points in the paint, outpacing the Rebels' total score for the game. Ole Miss were not nearly as productive in the paint, scoring just 20 points inside.
South Carolina continued to dominate in defense and rebounds on Saturday as they have throughout the season. The Gamecocks controlled the glass and outrebounded the Rebels 45-32.
Ole Miss recorded more offensive rebounds than South Carolina, holding a 15-12 advantage, but the Gamecocks made more use of their second-chance opportunities scoring 10 points, while the Rebels struggled and scored just 2 points from the offensive glass.
South Carolina denied shots all game on defense. The team recorded 8 blocks in the first half and 6 blocks in the second.
The Gamecocks had an efficient game shooting the ball while Rebels struggled. South Carolina hit 53% of their attempts, and Ole Miss shot just 29% from the field.
“Just being able to run the floor, getting easy baskets, is always a good thing,” Amihere said. “When you’re able to do that, then it gives you a little bit more confidence.”
Up 19 points after three quarters, South Carolina got to sit key players, allowing them to rest for tomorrow’s championship game.
South Carolina hopes to capture its seventh SEC championship win in nine years on Sunday, which would put the Gamecocks second all-time in SEC tournament wins. However, the team would still trail the record holder Tennessee by 10 titles.
South Carolina will look to avenge last year’s title game loss tomorrow at 3 p.m. as they take on Tennessee for the second time this season.


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CALLING ALL ARTISTS!
Would you like your artwork to feature on the front cover of a published book that will help give hope to people going through distressing times?
What picture do YOU feel would best portray the following book themes?…
#Emerging Proud through Suicide
#Emerging Proud through NOTES (Non- Ordinary Transcendent Experiences)
# Emerging Proud through disordered eating, body image and low-self-esteem
#Emerging Proud through trauma and abuse
Submit your ideas HERE by 31st Oct 2018, and they will go to a public vote to decide on each cover design….If your artwork is chosen, you will be named as the Artist for the specific book on which it’s featured, and get to advertise your work for free! Good Luck! ❤


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Kolay Campground Gawler Ranges National Park
Gawler Ranges National Park
Pitch a tent amid rocky gorges and valleys at the foot of a granite hill, or on a grassy plain. Relax under the stars at night and wake to the sound of birdsong, and the fragrant scent of the Australian bush. Offering views of Mt Fairfield, this campground is only accessible to 4WD vehicles and has unallocated camping for ten vehicles.
Access 4WD only.
Suitable for tents and camper trailers.
Facilities, long-drop toilet.
Campfires allowed (seasonal fire restrictions apply).
Number of campsites, unallocated - maximum of 10 vehicles.

domain: geography


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A portion of all proceeds
will be donated to the
The Indian Residential School Survivor Society (IRSSS) is a provincial organization with a twenty-year history of providing services to Indian Residential School Survivors.
The Indian Residential School Survivors Society began in 1994 as a working committee of the First Nations Summit. We were known as the Residential School Project, housed out of and as a part of the BC First Nations Summit. Our work was primarily to assist Survivors with the litigation process pertaining to Residential School abuses. In more recent years our work has expanded to include assisting the descendants of Survivors and implementing Community education measures (Indigenous & Non-Indigenous).
One of our Society’s goals is to continually expand our support to partner organizations and maximize access to culturally sensitive, emotional, mental, physical, and spiritual care.
Amnesty International is a leading organization for the cause of human rights and the campaign called 'No More Stolen Sisters'.
Violence against women, and certainly violence against Indigenous women, is rarely understood as a human rights issue. To the extent that governments, media and the general public do consider concerns about violence against women, it is more frequent for it to be described as a criminal concern or a social issue. It is both of those things of course. But it is also very much a human rights issue.
Indigenous women and girls have the right to be safe and free from violence. When a woman is targeted for violence because of her gender or because of her Indigenous identity, her fundamental rights have been abused. And when she is not offered an adequate level of protection by state authorities because or her gender or because of her Indigenous identity, those rights have been violated.


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By Rania Spooner and Neelima Choahan
A Tasmanian woman has reportedly become a mother at the age of 62, making her the oldest woman to give birth in Australia.
Channel Seven reported that the baby girl is the first child for the unidentified woman and her 78-year-old partner.
According to the report, the woman gave birth by caesarean section at Melbourne's Frances Perry House private hospital on Monday.
The baby was born premature but is said to be progressing well, along with her mother.
The couple is said to have conceived through IVF overseas, using a donor embryo.
It is reported the previous Australian record was held by a 60-year-old woman who gave birth in 2010.
A Gold Cost woman who had her first child at the age of 50 in 2011 is believed to be the oldest Australian woman to give birth to a naturally-conceived child.
In 2010, a woman gave birth to twins, conceived via IVF, in Perth at the age of 57.
In 2007, a 56-year-old Queensland woman gave birth to an IVF-conceived child.
According to the Australian Institute of Health and Welfare, a third of women who gave birth in 2013 were likely to be aged between 30 and 34 years.
In the same year, women aged 45 or over amounted to just 0.2 per cent of those who gave birth.
An earlier version of this story said that the mother was 63. Later reporting confirmed her age to be 62.


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HCMC – Former Hanoi chairman Nguyen Duc Chung has been sentenced to eight years in prison for being the mastermind behind the illegal purchase of water cleaning agent Redoxy 3C for Hanoi City, causing losses for the State.
He was found guilty of abusing powers while performing his official duties. Chung is serving a sentence of five years for appropriating the State’s secret files, so he must stay behind bars for 13 years in total, the local media reported.
The Hanoi People’s Court also handed down a jail term of four and 4.5 years to Vo Tien Hung, general director of the Hanoi Sewerage and Drainage Co., Ltd, and Nguyen Truong Giang, director of the Arktic Trading and Service Co., Ltd, respectively, for the same charge as Chung.
The court also asked Chung, Giang and Hung to compensate VND25 billion, VND7.1 billion and VND4 billion to the Hanoi Sewerage and Drainage Co., Ltd, respectively.
According to the court, Chung asked Germany’s Watch Water to research Redoxy-3C to purify lakes and rivers in Hanoi. The German firm later agreed to sell the water cleaning agent to the city at a competitive price of 8.5 euros per kilogram.
After the trial use of the first 100 kilograms, Chung did not ask Hung to buy Redoxy 3C directly from Watch Water but through Arktic, which was later found to be owned by Chung’s family.
From 2016 to 2019, Arktic imported more than 489,000 kilograms of Redoxy 3C at over VND115 billion and sold it to the Hanoi Sewerage and Drainage Co., Ltd for VND151 billion.
The acts caused losses of over VND36 billion for the State.

domain: law


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Still 4 Weeks Left & Still Room To Sign Up!!!
Mixed Martial Arts & Fitness Kids Performance Camp
Investment is only $125 per child for all 5 weeks and includes Kids MMA training gloves ($50 Value).
Each Tuesday and Thursday at 4:30 pm -5:30 pm starting on Tuesday June 25th, 2019 and ending July 25th, 2019 (No Class on July 4th) kids ages 5- 14 years old will be learning Boxing, Speed & Agility ,Self Defense , Kickboxing, & Grappling at our family friendly mixed martial arts & fitness facility in Oak Creek.
In addition to martial arts training, kids will be learning sport specific moves that will make them more athletic.
Classes will be held at Nova Gyms in Oak Creek : 6508 s 27th Street Oak Creek, WI.

domain: sports


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NEWS & PRESS RELEASES
Soccer weeks wrap up summer sports camps
Nearly 800 students participated in BBC sports camps on campus this summer, a special time of learning, growth, and fun.
Led by qualified coaches and leaders, August included Defender Soccer Camp for high school students and Big Blue Soccer Camp for children through eighth grade. The two weeks of camps wrapped up a successful summer season on campus.
Soccer instruction was led by BBC Women's Head Coach Chris Davis and Men's Head Coach Sean MacPherson.
"It was great interacting with the players on such character traits as sportsmanship, discipline, competitiveness, enthusiasm, and accountability," Coach Davis said. "Many greatly improved their soccer knowledge and skills while gaining conditioning for their upcoming soccer season."
Defender Soccer Camp helps students become better soccer players in both technique and tactics, prepares them for their seasons, and to honor Christ in all they do both on and off the field.
Big Blue Soccer Camp prepared students for their youth soccer teams. A variety of drills, modified games, and fun activities were taught and demonstrated.
"Many parents bring their kids to camp reminding me that they attended Big Blue themselves years ago," Coach Davis said. "It's fun developing another generation of youth soccer players in the Abingtons."
Full summer, fall sports
Earlier this summer, Defender, Lady Defender, and Big Blue basketball camps filled campus.
Lady Defender Basketball was led by Women's Head Coach and Assistant Athletic Director Amber Jacobs. Defender Basketball was led by Men's Head Coach and Athletic Director Mike Show.
Read more here.
For details on 2014 camps, contact email@example.com or 570.585.9322.
On the field, seven BBC Defender and Lady Defender teams will start seasons this fall -- men's cross country, golf, and soccer will be joined by women's cross country, soccer, tennis, and volleyball.
BBC is affiliated with the Colonial States Athletic Conference, the National Christian College Athletic Association, and the National Collegiate Athletic Association Division III.
For more on BBC Defender Athletics, go to www.bbcdefenders.com.
Baptist Bible College & Seminary offers an outstanding Christian education through on-campus, online, and other distance learning options. Students go beyond the ordinary, learning to think biblically, grow spiritually, and serve faithfully as they gain critical leadership and life skills.
To learn more, go to www.bbc.edu or call 570.586.2400.
Posted on: 8/14/2013 8:58:47 AM


James Penn has created an awesome wall mounted drawing robot aptly named Utensil, which can be used to create a wide variety of different artworks or designs using fabric markers, sharpies and other drawing implements. Check out the demonstration video below to learn more about the drawing robot which has this week launched via Kickstarter with the aim of raising $30,000 over the next 30 days.
Due to the modular structure of the Utensil wall-mounted robot, its designer is also testing other capabilities such as remote control, programmable multi-axis motion, laser cutting, milling and engraving to name just a few.
The Utensil robot measures 56 cm square or 22 inches and features a unique, patent-pending, cable drive system with closed loop feedback control that allows it to achieve its large-scale drawings without sacrificing performance. Enabling the Utensil robot to both provide high-speed when drawing as well as carry out heavy duty tasks such as milling or laser cutting. “Imagine you have an awesome idea for a t-shirt. You could place a custom order, but then you’d have to wait for it, and probably pay a heavy premium (plus shipping). You could also screenprint it yourself, but then you’d have to deal with the mess and complexity. Given these limited options, you might be inclined just to forget about it.”
For more information, full specifications and a list of all available pledges jump over to the official Kickstarter crowdfunding campaign page by following the link below.
Latest Geeky Gadgets Deals
Disclosure: Some of our articles include affiliate links. If you buy something through one of these links, Geeky Gadgets may earn an affiliate commission. Learn more.


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