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Rice University biophysicist Michael Deem was named as senior author on a paper about the work that was submitted to Nature
Below is an article stating that He Jiankui, the Chinese scientist who gene-edited human babies, wasn't acting alone – as GMWatch predicted. His collaborator was reportedly an American scientist, Michael Deem, though Deem's lawyers are disputing the reports in carefully worded statements that don't actually deny his involvement.
Let's hope that appropriate sanctions are taken against Deem. It isn't acceptable that He Jiankui is put into the role of the sole fall guy.
American scientist played more active role in ‘CRISPR babies’ project than previously known
By JANE QIU
STAT, JANUARY 31, 2019
BEIJING — An American scientist at Rice University was far more involved in the widely condemned “CRISPR babies” experiment than has previously been disclosed. Most notably, STAT has learned that Rice biophysicist Michael Deem was named as the senior author on a paper about the work that was submitted to Nature in late November.
Deem’s prominent authorship indicates that a respected American researcher played an instrumental role in the controversial project, which sparked a worldwide furor. His involvement could have encouraged volunteers to join the experiment and lent credibility to He Jiankui, the Chinese scientist who led the work.
Emails provided to STAT show that Deem was listed as the last author — which, in the life sciences, is typically reserved for the senior researcher who oversees a study. The paper, titled “Birth of twins after genome editing for HIV resistance,” has another nine contributors, including He as the first author, where the person who makes the most hands-on contribution is credited.
The now infamous Chinese scientist created a sensation when he announced the birth of twin girls, whose genes had been altered using CRISPR technology, before an international conference in Hong Kong last November. He received intense criticism for violating scientific and ethical norms against starting a pregnancy with genetically modified human embryos, and Nature quickly decided not to proceed with peer review of the paper.
He was fired by the Southern University of Science and Technology in Shenzhen last week after an official investigation found that his work seriously violated Chinese government rules, according to the Xinhua News Agency. The inquiry also concluded that He’s project team involved “overseas personnel.” It didn’t name Deem or detail his contributions, but he’s the only foreign scientist known to have been involved in He’s genome-editing research.
A Chinese scientist who worked on the project said Deem was more than a bystander: Deem collaborated with He on the experiment and participated as a member of the research team during meetings with several volunteers in 2017 as they were recruited and went through the informed-consent process — a crucial component of a clinical trial. Deem helped to obtain the volunteers’ consent, speaking with them through a translator, said the Chinese member of the team, who asked not to be identified because the person was not authorized to speak to a reporter.
“As a prominent scientist from an elite university in the U.S., Deem’s presence is likely to have a significant role in persuading potential candidates to jump on board,” said Jia Ping, a human rights lawyer who is founder and chief executive officer of the Beijing-based nongovernmental organization Health Governance Initiative. They would not have known that neither Deem nor He had any experience conducting clinical trials.
Researchers contacted by STAT say it’s important to get to the bottom of Deem’s role. “The nature of the incident would be quite different with or without his involvement,” said Jennifer Doudna, a genome-editing pioneer of the University of California, Berkeley.
Deem, a bioengineering and physics professor, was He’s Ph.D. adviser when He was a graduate student at Rice between 2007 and 2010. Deem told the Associated Press in its initial story on the project in November that “I met the parents. I was there for the informed consent of the parents” — referring to the twins’ parents — though why he was there was unclear. His remarks prompted Rice to launch an investigation into Deem’s involvement.
Then last month, Deem’s attorney issued a statement saying that, “Michael does not do human research and he did not do human research on this project.”
While Deem might not have physically done the lab work, such as handling the embryos, being listed as an author, especially the last author, of the CRISPR-babies paper is strong evidence for Deem’s participation in the research in a significant way, said Hank Greely, a lawyer and bioethicist at Stanford University.
An early draft of the paper listed He as the last author — Deem was the second-to-last author, according to excerpts provided to STAT. But for unknown reasons, the order of authors was changed in the version submitted to Nature in late November: It listed He as the first or lead author, and Deem the last.
Deem has declined to comment. But his lawyers issued a statement this week denying that he was “the lead, last, or corresponding author” on the paper submitted to Nature: “Michael Deem has done theoretical work on CRISPR in bacteria in the past, and he wrote a review article on the physics of CRISPR-Cas. But Dr. Deem has not designed, carried out, or executed studies or experiments related to CRISPR-Cas9 gene editing – something very different.”
Deem’s lawyers, David Gerger and Matt Hennessy of Houston, disputed the claim that he was present when the parents of the gene-edited twins went through the consent process. “Dr. Deem was not in China, and he did not otherwise participate, when the parents of the reported CCR5-edited children provided informed consent,” they said, in a statement that seems to contradict what the AP reported. The AP told STAT that it accurately quoted Deem and that it “stands by its story.”
The lawyers did not respond to follow-up questions about whether they denied Deem’s involvement in the CRISPR babies project in any way.
Paul Knoepfler, a stem-cell biologist at the University of California, Davis, said Deem’s participation might have made He feel more confident about proceeding with the experiment. “I don’t think He Jiankui would have done the project if Deem had been strongly disapproving of it,” the UC biologist said. The fact that his lawyers didn’t categorically deny Deem’s involvement in the project is telling, suggesting that he did have some sort of a role, Knoepfler added: “My best guess is he was intellectually involved in the project in some important way.”
STAT has also found that Deem and He co-authored two preclinical papers that tested the CRISPR gene-editing technology in mouse, monkey, and human embryos — without establishing any pregnancy in humans. Both papers’ “Author Contributions” statements say that Deem designed the project and wrote and edited the manuscript. STAT was provided one of the papers and a scientist with a copy of the other manuscript read aloud its author-contributions statement over the phone.
One paper — submitted to Nature along with the CRISPR-babies paper in late November — modified the CCR5 gene, which encodes a protein that helps HIV enter and infect cells, the same gene He claimed he had altered in the twins to protect them against infection with the AIDS-causing virus. The other paper, which reported on the editing of the PCSK9 gene that encodes a protein that helps regulate the level of cholesterol in the bloodstream, was submitted to Science Translational Medicine. Both were rejected.
Both journals said they couldn’t comment on any possible submissions because they are confidential. But editors at both journals said they have a policy of automatically sending an email to every author of a submission. The email notifies the individual that they are listed as an author and includes the title of the paper. This gives researchers the opportunity to notify the journal if they were unaware of the paper, have not approved of the content/submission, or do not qualify as an author. This can be grounds for rejection, and the journal would not send it out for peer review under such circumstances.
Deem’s lawyers said “he did not authorize submission of manuscripts related to CCR5 or PCSK9 with any journal, and he was not the lead, last, or corresponding author on any such manuscript.” But in response to followup questions from STAT, they then acknowledged that Deem was listed as an author on all three gene-editing papers and said he had had instructed the journals to remove his name from all the manuscripts.
In addition to the submissions to Nature and Science Translational Medicine, Deem and He have eight published papers together, the latest in 2017. While none is related to gene editing, they show that the two have closely collaborated since He graduated from Rice.
To many researchers, a key question is whether Deem’s involvement in the CRISPR babies trial broke U.S. rules on human-subjects research, because he didn’t obtain approval from Rice University. Even if he didn’t use federal funds for the work, government regulations require researchers to seek approval from an ethics committee at their institution should they want to carry out clinical trials abroad.
At least two active federal grants — from the National Science Foundation and the Department of Energy — contributed to Deem’s recent work in his own lab. The NSF provided a five-year, $12-million grant, which will come to an end this August, for Rice’s Center for Theoretical Biological Physics that supports Deem’s research.
Neither Deem nor his lawyers would comment on whether he has broken federal regulations on human-subjects research or whether he used any of his federal grants on the CRISPR babies work.
NSF’s Office of Inspector General said it could not comment on the existence of an investigation, and DOE did not respond.
Rice has said in a statement that it was unaware of the CRISPR babies work, and that to its knowledge, none of the clinical work was performed in the U.S. The university began a full investigation in late November and wouldn’t offer further comments.
If Deem violated human-subjects protection regulations, said Dr. Kiran Musunuru, a genome-editing expert at the University of Pennsylvania, “it would be a career suicide.”
Any federal grants Deem has could be in jeopardy. “That could be a very powerful sanction,” said Greely. “It could put him out of business.”
Regardless of the outcome of Rice’s investigation, Deem may not remain at the university for much longer. Last June, he gave a talk at the City University of Hong Kong, apparently as part of a job interview for the deanship of the College of Engineering. He was offered the job a few months later, a professor at the university told STAT. Deem was supposed to assume the position in early January, but the university has appointed an acting dean instead, the professor added.
Deem’s possible involvement in the CRISPR babies experiment has led the Hong Kong university to review the contract, which is now “pending on the result of the investigation undergoing at the Rice University,” said the Hong Kong university’s press office. It would not say if it would terminate Deem’s contract if he is found to have been involved in the project. His lawyers would not comment on the matter.
“If Deem was an active participant in the research, then I don’t think it would be appropriate” for him to be a university dean, said Greely. “I’d not want to hire him, and I’d advise other universities not to hire him, because he has shown very bad judgment at the very least.”


Ten Regional Meetings will be held this fall. These meetings will provide 3.0 Continuing Legal Education credits in the areas of ethics, office management, substance abuse, and/or elimination of bias. Lunch will be included at each meeting. Each Regional Meeting will begin at 10:30 a.m. and will last until, approximately, 1:30 p.m. One of The State Bar’s Officers will attend each meeting.
CLE: 3.0 Attendance Credits in Ethics & Law Office Management
Click on Date or Location below to register.
Pursuant to WVC §11-10A-6, the Governor shall appoint the Chief Administrative Law Judge from a list of three qualified nominees submitted to the Governor by the Board of Governors of the West Virginia State Bar for a four-year term. Therefore, the Office of the Governor is seeking nominations for the position of Chief Administrative Law Judge of the West Virginia Office of Tax Appeals. The West Virginia State Bar Board of Governors will select three nominees for consideration by Governor Tomblin. Applicants must be admitted to the practice of law in West Virginia and have five years of full-time or equivalent part-time experience as an attorney with federal or state tax law experience or have served as a judge of a court of record.
Applications, with supporting resumes and letters of reference,must be received by Anita R. Casey (firstname.lastname@example.org
no later than noon on September 7, 2016.
To review a copy of the applicable statute, CLICK HERE
In August a reprint of the 2016 Michie’s West Virginia State Court Rulesvolume was issued. Due to errors and omissions in the previously issued 2016 volume, as well as the supplement thereto, this reprint completely replaces the January softbound volume AND the May 2016 softbound supplement for the state court rules.
Remember that the print version is only as current as the last edition or supplement’s publication date. For the most current, up-to-date version of West Virginia Rules of Court, always rely upon those on the Court’s website at http://www.courtswv.gov/legal-community/court-rules.html
According to a recent article from the ABA Journal, new email scams with fake disciplinary warnings & bar announcements are targeting lawyers throughout the country. Click here to view the ABA article.


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Thano is a village situated in Dehradun district of Uttarakhand which falls in India. The geographical coordinates i.e. latitude and longitude of Thano is 29.8085504 and 77.8763294 respectively. IST(Indian Standard Time) followed in Thano is located in the UTC time zone 5:30. The currency code for Indian rupee is INR. The currency used in Thano is Indian rupee.
|Village / Town / city / etc || Thano|
|Taluk/Block || Raipur|
|District || Dehradun |
|State || Uttarakhand|
|Continent || Asia |
|Time Zone ||IST ( UTC + 05:30) |
|Currency || Indian Rupee ( INR )|
|ISD Dialing Code || +91|
|Date format || dd/mm/yyyy|
|Driving side ||left|
|Internet cTLD ||in|
|Language ||Hindi, Sanskrit|
|Time difference ||18 minutes|
Thano website and dialing Code
Connection to phones and mobiles in Thano can be reached by adding Indian country dialing code +91 from any where the globe. The country top level domain extension is in
. so many people register their websites under this domain extension.
Since India is known for its Supermacy in Information technology, Thano also has access to the internet.
The basic communication media like radio, TV, Newspapers are also available in Thano.
Thano travel guide
Thano travel guide provides various traval information like nearest railway station, nearest airport, route map, tourist places and more travel related information. Thano people speakes Hindi, Sanskrit as their main communication language. as well as it is a mother tongue of most of the peoples. Some people in Thano may speake english as their second langauge.
The following Thano map is comming from google. You can use the Thano map in satilite mode and normal mode. The plus and minus symbol can be used to enlarge and reduce the Thano map size.
Nearby villages from Thano
The following villages are surrounding villages to Thano.The given distance are kilometer from Thano and it is based on the straight line distance from Thano.
Nearest railway station to Thano
Doiwala railway station is the nearest railway station from Thano. The straight line distance from Thano to Doiwala railway station is around 10.8 kilometer. The nearest railway station and its distance from Thano are follows.
|Doiwala railway station||10.8 KM.|
|Harrawala railway station||11.1 KM.|
|Rishikesh railway station||16.3 KM.|
|Virbhadra railway station||18.5 KM.|
|Kansrao railway station||18.8 KM.|
Nearest airport to Thano
Nearest airport from Thano‘s is Jolly Grant Airport which is situated around 6.0 KM ditance.
|Jolly Grant Airport||6.0 KM.|
|Sarsawa Air Base||80.9 KM.|
|Karnal Airport||127.0 KM.|
Village name start alike Thano
The following village/town name start like Thano. The first four character of the given village name are starts alike Thano. Than
- Thana Amarsingh
- Thana Dang
- Thana Dariyav Ganj
- Thana Gaddi
- Thana Galol
- Thana Kalan
- Thana Khas
- Thana Kurad
- Thana Kurd
- Thana Kushnoor
- Thana Shankar Dwari
- Thanda Pani
- Thande Wala
- Thandi Kassi
- Thanichiyam A / C
- Thanpur Nigoh
This Thano website provide answer for the following queries. 01.Thano district ?. Ans:Dehradun. 02.which is a nearest railway station to Thano?. 03.How to reach Thano? 04.Thano map. 04.Which are the nearest tourist places around Thano?. 05.Nearest schools in and around Thano. 06.What is the pincode of Thano. 07.What is the STD code of Thano?. 08.Temples in Thano. 09. nearest bank ATM to Thano.
We are trying to provide best service and information about Thano to the user, even though we are not liable for the accuracy of the data due to various factors. Kindly check the appropriate authorities for the accuracy of the information about Thano before using our information.

domain: travel


Writing for BBC Africa, correspondent Andrew Harding shares some of the lessons learned from the 2010 World Cup held in South Africa. FIFA’s 2014 World Cup has been plagued with some of the same challenges that have led to anti-World Cup protests throughout Brazil, mostly Sao Paolo and Rio. Like South Africa, the 2014 is marked by hope and despair. Parties and murals demonstrate the conflict that Brazilians have over the abject poverty that many in the country face, while pouring billions of dollars into venues and infrastructure to host the 2014 World Cup. Coupled with controversy surrounding contracts that will mainly benefit FIFA as opposed to locals, the lead-up to the World Cup that many hope will land Brazil a 6th win, has been hauntingly similar to South Africa.
“It was a success for Fifa and the corporate sponsors made a lot of money, but it left local businesses and the state floundering,” said Johannesburg-based researcher Dale McKinley, pointing out that of the eight stadiums built or refurbished for the World Cup, only one – the iconic FNB stadium outside Soweto – “is financially viable”.
Harding offers an example of the Matsafeni village located outside of Nelspurit in South Africa. He writes:
Four years after a giant orange stadium appeared on their land, the inhabitants of Matsafeni village outside Nelspruit in South Africa say they are still waiting for their World Cup legacy. ‘They lied to us and betrayed us,” said Imaan Milanzi, a community liaison officer, pointing to a muddy hole in the ground surrounded by rubbish, bushes and banana plants.
Half a dozen people, holding battered old plastic paint tubs, had formed a casual queue (line), waiting for their turn to access the borehole – their one, trickling water supply.
‘Things didn’t go as planned,’ said Mr. Milanzi, of the local government’s redevelopment plans.
‘They first promised to supply water, upgrade houses and roads. But they just built the stadium and disappeared.'”
While positive things occurred like the improvement of the high-speed Gautrain which connects OR Tambo airport with Johannesburg and Pretoria, other challenges have emerged like pricing for the Gautrain which most South Africans cannot afford and the introduction of tolls on the improved roadways. The same challenges are now facing Brazil.
Even Brazilian soccer (football) star Pelé and the Catholic Church have spoken out about the enormous expense that the Brazilian government has pumped into the games while failing to meet the needs of the people.
Jonathan Watts of The Guardian writes:
“But ever since mass protests during the Confederations Cup last year, public awareness of the social and economic costs of the tournament have made many uneasy about displays of enthusiasm. As compared with previous World Cups, public support is low. A poll by the Pew Research Centre suggests that 61% of the public feel that hosting the World Cup was a bad idea, because it diverts resources that could be better spent on public services such as healthcare.
Everyone from Pelé and Romário to the Catholic church has criticized the expense and delays. The footballer-turned-congressman Romário has described the impact on state funds as “the biggest heist in the history of Brazil”. Last week the bishops’ conference issued a ‘red card’ to the organizers for squandering public funds and evicting people for stadium construction.
‘The church wants to contribute to the public debate and express its concern with … the inversion of priorities in the use of public money that should go to health, education, basic sanitation, transportation and security,’ it said.”
While many think of the 2014 World Cup already as a win for the people of Brazil, similar to what many people thought of South Africa’s win to host the 2010 games, the growing anti-2014 World Cup protests serve as a reminder that all that glitters isn’t gold.
This post was written by Nsenga K. Burton, Ph.D., founder & editor-in-chief of the award-winning news site The Burton Wire.
Read more about this story at BBC Africa or The Guardian.
Like The Burton Wire on Facebook. Follow us on Twitter @TheBurtonWire.
From all I’ve read and heard it will be a miracle if people don’t get hurt in the unfinished structures. The corruption caused the cost to jump over ten times of the original estimate. I am outraged that Brazil displaced families that are now homeless.
Thanks for the post about World Cup. Just a tip about those who don’t live in countries that stream world cup online. You can use UnoTelly to remove the geoblock and stream World Cup 2014 in your country free https://worldcup.unotelly.com
Comments are closed.


Ball blasts Gipson on Senate floor, then accused of hitting "a new low"
Sen. Greg Ball, R-Patterson, Putnam County, criticized fellow Sen. Terry Gipson, D-Rhinebeck, Dutchess County, on the Senate floor during the budget debate today, questioning whether Gipson knew anything about a deal to help Dutchess County.
Ball pressed Gipson, a freshman senator, to say when he learned that the budget includes $5.25 million to allow the county to repeal an energy tax.
Ball and Assemblywoman Didi Barrett, D-Hudson, Columbia County, put out news releases about the money, and Gipson did too.
Gipson said he became aware of the money in the budget in recent days and waited to make any announcements publicly until he was sure the money was secured.
It wasn't enough for Ball, who responded, "I’m happy with the non-answer. Thank you."
Ball has been holding events to try to find opponents to Gipson, and Ball heads the region's campaign committee for Senate Republicans.
Sen. Mike Gianaris, D-Queens, came to Gipson's defense and ripped Ball on the Senate floor. Gianaris heads the Senate Democrats' campaign committee.
Ball wouldn't yield for Gianaris' questions.
"Interesting that Senator Ball stands here attacking members of this body, when we’ve tried hard to deal collegially with each other and had a rule about not personally attacking or using attacks for political purposes on this floor," Gianaris said.
"I should say I’m not at all surprised that he has no regard for that rule, as he doesn’t have regard for many things in this chamber. But to then not yield for questions," Gianaris continued.
Before order was restored, Gianaris concluded, "For Senator Ball to act the way he did and then to not yield himself for a question is a new low from him. So not surprising, not a tremendous amount of courage on his part."


text:
Harner, J. L. (2008). Literary research guide: An annotated listing of reference sources in English literary studies (5th ed.). New York: Modern Language Association of America.MLA Citation
Harner, James L. Literary Research Guide: An Annotated Listing of Reference Sources in English Literary Studies. 5th ed. New York: Modern Language Association of America, 2008.

domain: library


text:
Reneé Edward has a lot on her plate. She took over as President of the Reneé-Gal company from her father a few months ago. Just in time for a merger with a new parent company. As if that timing was not bad enough she finds out several Junior Executives have been ruining the merger from within.
Just as she is scrambling to pick up the pieces, Ruben Blackthorne strolls into her life. He is sexy, tall and clearly into her. Though she is excited about this new development in her love life Reneé finds it a little hard to juggle the new addition. As everything in her life finally seems to fall into place for the first time in almost a year Reneé finds herself confused as Ruben begins to pull away. Had she imagined their connection? Were things moving too fast? Lost and confused, at least she has her family and her fellow Deltas to get her through.
hang ups with the negotiations right?”
could, with help, oust me and make a more agreeable deal.” Naomi’s eyes widened as she set down her mug.
“Wait, what? Isn’t that illegal or something? Are you going to sue them? Can you save the deal? How did you find out?”
sending in one of their acquisitions and negotiations guys to do the rest in person. That way there can be no mistakes. Uncle James is all for this. He says the guy they are sending is the same one that approached him and Dad years ago. That he is a trustworthy guy. I still don’t know. While I appreciate that they still want to negotiate it almost feels like I am being chastised for not
having a better handle on the board.” Some of the stress crept back in as Reneé finished.
load will be lighter. There are maybe six months left, yes a hard six months but there is light at the end of the tunnel.” She gave another squeeze before letting go and grabbing her cup again. “Now eat your
sandwich!” Rolling her eyes Reneé complied, knowing full well Naomi wouldn’t let her talk again until at least half the sandwich was gone.
to stand next to her, beaming at Naomi.
Gretchen is a Seattleite who loves her home. She has a day job as a Program Coordinator at a local university. She is a struggling Indie Author, struggling as in she is trying to make her living writing books. She loves to read, write and create characters. As well as knit and binge watch Netflix. She is also on a sporadic book blog and internet radio show with some of her college friends. She currently lives with her husband and their mischievous Rotti mix, who always seems to find something new she shouldn’t be chewing on.

domain: literature


text:
9 Patch Star Patchwork Template ~ Matilda's Own High Quality Acrylic Template Set
Try your hand with this different 9-patch design, also known as ‘Curved 9-Patch’ or ‘Improved 9-Patch.’
Includes printed instructions, ¼” seam allowance and registration holes for marking.
5 Template Pieces
3 Sizes of finished block available 6", 9" and 12" (Please choose your size)
Rotary cutting is made easy when you use the Matildas Own Rotating Mat and a small wheel rotary cutter!
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domain: design


text:
SPL Wrap: Celtic finish on high, Motherwell second
Neil Lennon's men finished the campaign 29 points ahead of the second-placed Motherwell with their latest success.
The win – Celtic's 31st of the season – came despite an arm-wrestle that lasted more than an hour in Glasgow.
Anthony Stokes eventually opened the scoring in the 64th minute before substitute Giorgos Samaras doubled their lead from the penalty spot.
A Filip Twardzik own goal 11 minutes from the end set up a nervy finish but Kris Commons was on hand to wrap up the win for Celtic.
It was fitting that Commons scored the decisive goal, his 27th of the season, as the attacker finished as the league's top scorer.
Celtic were then presented with the trophy as their players and fans begun celebrations in the Scottish capital.
Other results on Sunday saw Motherwell finish second after a 1-0 win at Aberdeen.
Craig Reid scored the game's only goal in the 93rd minute, as Motherwell leapfrogged their opponents.
Both sides will take part in next season's UEFA Europa League qualifying.
And Inverness Caledonian Thistle moved into fifth after a 2-0 home win over St. Johnstone, which came thanks to goals from Ryan Christie and Greg Tansey.

domain: news


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Three men held at the Guantanamo Bay detention centre have been formally charged in connection with the 2002 Bali nightclub bombings and other plots in Southeast Asia after 18 years in US custody.
But defence lawyers insisted afterwards the long-delayed process was so flawed it may have to be repeated.
The men returned to the secure courthouse encircled by razor wire on the US base in Cuba amid defence complaints about courtroom interpreters, that caused what was supposed to be a brief arraignment before a military commission into a two-day affair.
It was a rocky start to a case already expected to be complex because of the prolonged detention without charges for the three - an Indonesian and two Malaysians - and the brutal treatment they endured in CIA custody.
Encep Nurjaman, the Indonesian militant leader known as Hambali, and the two men face charges that include murder, terrorism and conspiracy before the commission, which is a hybrid of military and civilian law. They have not yet entered pleas.
The start of their long-delayed case comes as US President Joe Biden said he intends to close the detention centre, which now holds 39 of the 779 men who were brought to the base following the September 11 attacks.
"Frankly, after this two-day arraignment, I didn't see any evidence that he would get a fair trial," said Christine Funk, the lawyer for one of the Malaysian defendants.
The defence complained the Malaysian interpreter's language skills were so poor that at least one defendant couldn't understand what was being said in court.
The defence also complained another Malay interpreter was improperly working for the prosecution because he previously assisted the prisoners when they appeared before a review board at Guantanamo.
The defence further complained the Indonesian interpreter had been overheard disparaging the men as terrorists who should be killed.
The judge, a Navy commander, allowed the proceeding to go on amid despite repeated objections.
Defence lawyer Brian Bouffard, who represents Malaysian defendant Mohammed Nazir bin Lep, said the arraignment was so flawed it should be done again.
"This one wasn't done right," Bouffard said.
The trio is alleged to have been involved with the October 2002 suicide bombings of Paddy's Pub and the Sari Club in Bali, Indonesia, and the August 2003 suicide bombing of the JW Marriott in Jakarta, Indonesia.
The attacks together killed 213 people, including 88 Australians.


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I am hoping to travel to Greece this summer. I had planned on Ibiza with some friends but have since started going out with a great guy and would like our first holiday together to be just us.
We're looking for something fun but yet with some good sights to see good beaches and a lively enough nightlife and yes with a bit of romance thrown in there Could anyone recommend a place in Greece that would suit PLEASE??
I have been looking up loads of different websites and there are just so many different parts of Greece I feel like my head is going to explode trying to decide....Would really appreciate some advice PLEASE and Thank you in advance.
Where is the best place to go in Greece??
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- 24 Tipping in Turkey ...and Europe
- 25 Greece trip report - winter in the center - Epirus, Pelion etc

domain: geography


text:
Still Room To Register For 2-Session Photography Workshop In Paynesville!
Photographer Carol Weiler will be presenting a two-session photography workshop at the Paynesville Branch of Great River Regional Library (GRRL) on Thursdays, Nov. 10 and Nov. 17, from 6:30 - 8:00 p.m. Session One will include tips on how to take better photos, and Session Two will teach you how to make those digital photos even better with digital photo editing. Sign up online for one or both sessions, or call the Paynesville branch during open hours at 320.243.7343. Weiler holds a B.F.A. from Pratt Institute. She is a photographer, graphic artist and web designer. She has also served as an arts educator from the elementary to the college level. She has taught photography locally at the College of St. Benedict and the Paramount Visual Arts Center. Weiler has exhibited black and white and digital photography in web-based, national, regional and local juried and invitational shows since 1981. Pictured is "Zinnias", one of Carol's photos.
This workshop is funded in part with money from Minnesota's Arts and Cultural Heritage Fund.


The Hamad International Airport (HIA) has become the first airport in the region to obtain Smiths Detections HI-SCAN 6040 CTiX, which offers advanced screening of carry-on baggage at security checkpoints using Computed Tomography (CT) X-ray. HIA selected this equipment as it enables the airport operators to deliver the highest levels of security and optimises checkpoint performance by expediting the screening processes helping improve the passenger experience. This cabin baggage screening equipment uses a CT gantry that rotates at a constant speed as baggage is carried through on its conveyor belt. Hundreds of images are taken of each bag to create 3D imagery in real-time, allowing for more accurate assessments of the bags contents. This investment in advanced screening technology allows passengers to keep electronic devices and liquids in their hand baggage.
Source: Civil Aviation Authority-Qatar


Chicago's Field Museum marshals high interactivity with mobile campaign
The Field Museum of Chicago's recent mobile campaign generated higher-than-average NFC and QR code interactions.
The natural history museum had guests use their smartphones to engage with brand content appearing on signage away from the museum. The Field Museum worked with Blue Bite, which offers mobile out-of-home solutions, and DDB Worldwide to develop the "1893 World's Fair Exhibit" campaign.
"The Field Museum wanted to promote its newest 1893 World?s Fair Exhibit, as well as its updated mobile app with additional features, allowing users to stay in touch with The Field Museum and have a more engaging experience when visiting the museum," said Mikhail Damiani, CEO and cofounder at Blue Bite, New York.
"Mobile was an integral part of the strategy with the goal of getting users to download The Field Museum mobile app," he said. "As opposed to just being an afterthought or bolt-on to an existing campaign, mobile was woven through the entire strategy.
Campaign signage and mobile app view
The month-long campaign in November generated 60 percent more mobile engagements than any comparable out-of-home Blue Bite campaigns in Chicago to date, according to Mr. Damiani.
The campaign's signs showed the back of a person's head. The person appeared to be looking toward a place or event in Chicago 1893.
The ad copy read: "See What They Saw," enticing passersby to engage via their smartphones.
People with an NFC-enabled smartphone could tap their phone on the signage to instantly download the museum's application. Users without an NFC-enabled phone could snap a picture of the signage's QR code to access the same content.
The Field Museum app featured a 360-degree view of the sign's scene. Users could save pictures and share them via social media.
The campaign placed signs at bus shelters, transit platforms and inside trains and buses. Some magazines also featured campaign ads, which included the QR codes and encouraged readers to download The Field Museum app and explore Chicago.
The Field Museum mobile app
Adding mobile engagement to marketing already being delivered on the out-of-home network gives advertisers a way to make their ads more interactive and drive engagement levels.
"One of the challenges we face in many of these campaigns is incorporating the mobile engagement into the physical media in a way that doesn?t fight with the creative, especially in a campaign like this, where the copy is so artistically crafted," Mr. Damiani said.
"We have to find a balance between having a visible and obvious mobile call-to-action with the QR code and NFC that will get users to engage, while at the same time preserving the impact and style of the underlying creative," Mr. Damiani said. "I think we achieved a perfect balance in this case."
Kari Jensen is staff writer on Mobile Marketer, New York


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Halloween Cupcakes| Pumpkin Cupcakes. At Your Doorstep Faster Than Ever. Combine the pumpkin, eggs, oil, vanilla, and sugar. Stir together the remaining ingredients and add to the pumpkin mixture, mixing just until blended.
Once the cupcakes have cooled, attach the star frosting tip to the disposable piping bag and fill with frosting. Gently squeeze the piping bag and frost each cupcake as shown. Mix flour, golden brown sugar, and pumpkin pie spice in large bowl. You can have Halloween Cupcakes| Pumpkin Cupcakes using 12 ingredients and 7 steps. Here is how you cook it.
Ingredients of Halloween Cupcakes| Pumpkin Cupcakes
- You need 1 of egg.
- It’s 1/2 cup of sugar.
- It’s 1/3 cup of oil.
- It’s 1 tsp of vanilla extract.
- You need 1 of all-purpose-flour.
- It’s 1 tsp of cinnamon.
- It’s 1/4 tsp of baking soda.
- It’s 1 tsp of baking powder.
- Prepare 1 pinch of salt.
- Prepare 1 cup of grated pumpkin.
- Prepare As required of Buttercream frosting or any frosting Chocolate chip cookies.
- It’s As required of Chocolate sprinkles or any sprinkles.
Whisk egg, canned pure pumpkin, vegetable oil,. These super cute and easy Halloween cupcakes with pumpkin faces are a perfect addition to any Halloween party or just something fun to make for the kids. It probably won't be long before you start to realize that I have a major thing for cupcakes! I am absolutely addicted to making them and of course, I love to eat them.
Halloween Cupcakes| Pumpkin Cupcakes instructions
- Preheat oven to 180°C and prepare a cupcake pan with liners. .
- In a large bowl add egg, sugar, oil and vanilla..
- Beat for a minute and then add flour, cinnamon, baking powder, baking soda and salt..
- Beat for a minute, then add pumpkin and stir to combine, (Do not to over mix!)..
- Fill cupcake tins about 2/3 full. Bake at 180°C for 18-20 minutes or until golden brown..
- Remove from oven and allow to cool completely before frosting and decorate. .
- Note: Watch the video to decorating the cupcakes..
I love icing cupcakes, and having a pumpkin-on-pumpkin combo for these HalloweenTreatsWeek cupcakes makes me happy: Pumpkin Squared! Make my pumpkin frosting at least a half hour ahead of time if possible, since the pumpkin in the icing make sit a bit softer than the standard cupcake icing made with butter and confectioner's sugar. Cinnamon, nutmeg, ginger, and cloves transform boxed yellow cake mix into a delicious spice batter that acts as the base of these Halloween cupcakes. Just pipe on green frosting and top with candy for the cutest pumpkin cupcakes ever! Source: Better Homes and Gardens These Pumpkin Cupcakes are so easy to make with tinned pumpkin puree, but you can use raw grated pumpkin if you can't find the canned kind.
Living Greener for Good Health By Consuming Superfoods Learning to slow down and enjoy your life is one aspect of adopting a green lifestyle that a lot of folks appreciate. Despite the fast pace of our modern world, you can accomplish this. We should take a step back and fix diseases before they come about. Unfortunately, most people don’t care about their health because they believe they can take a pill to fix the problem later on. It isn’t possible to turn around without hearing about the newest pill to cure you of your health problems. Of course, you may get better by taking a pill but not if you continue the same old negative habits. Unlike buying a car, you cannot exchange your burnt-out body for a new one. You have to take care of your health while you can do so. Proper nutrition is essential for your body to work at optimum levels. When you put food into your mouth, do you pay attention to the nutritional value or simply eat anything tastes good at the time? How often do you fill up on mini mart junk food, or oily fried foods from the local fast food restaurant? Since people choose to consume things full of sugar, starch, and fat, more and more illnesses are cropping up. The foods we are ingesting are causing obesity, diabetes, and high blood pressure of epidemic proportions. People are opting to eat better now that they are aware of how important food choices are to their health. Lots of healthy food are now available at your local health food store or farmer’s market. Most probably, your local grocery store today has an organic food section. In the organic food section, you’ll find superfoods. That name has been given to 14 foods that have been proved to delay certain diseases, or even overturn them. You will discover that you think more clearly when you begin to consume these foods. You will start to feel a lot better when you choose to ingest the superfoods rather than junk food. By getting the correct nutrition, your body will run the way it is supposed to work. In this case, the immune system is better able to fight off any illness. You should have some superfoods in your diet each day. Foods such as beans and berries are excellent. Leagy greens, such as broccoli, spinach, and green tea. Whole grains, and oats, together with a variety of nuts, mainly walnuts. Make sure you include proteins such as soya, yogurt, salmon, and turkey, as well as orange fruits and vegetables like oranges, pumpkins, and tomatoes. Making these foods a normal part of your diet will eliminate your weight gain problems. Green living provides you with a solid diet plan, with all of the right ingredients for better health. Your immune system will be rebuilt, and your body can ward off diseases. Ensure your future health by switching to healthy eating habits now.

domain: food


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Miami Heat tickets are available for sale.
If you're looking for parking lot near American Airlines Arena or other NBA venues, choose event date, click on "View Tickets" and choose "X" box for "Parking" field, that's where you will see Parking Pass on sale.
Here's upcoming Miami Heat schedule as below:
Note: They offer courtside, Dewars club access, baseline, VIP private suites, front row floor seats, and lower / upper level section seats available.
As for courtside seats or Dewars club access, click on "View Tickets" and scroll down to the end of page. Either courtside or Dewars will be shown under the "Section and Row" field.
Miami Heat joined NBA as an expansion team in 1988, and Miami Heat basketball arena is called American Airlines (AA) arena.
When Shaq O'Neal was traded to Heat from Lakers in summer 2004, he promised to bring NBA championship trophy for Heat fans, and he did on his second season with Miami. O'Neal and Wade helped Miami Heat beating the Dallas Mavericks in six games and winning the 2006 NBA Championship for the first time in Miami Heat history.
Heat basketball tickets would be in the hottest NBA tickets for a long time once LeBron decided to leave Cleveland Cavaliers and join the Heat with superstars Bosh and Wade before the 2010-2011 season!
Since Lebron finally helped Heat winning second NBA championship in 2012, thenl won again in 2013. They are so hungry to win another NBA championship with James, Bosh and Wade!
If they makes playoffs, shop for Heat playoff tickets. If they win Eastern Conference championship title, shop for tickets for NBA final.Browse Heat schedule and buy your Miami Heat tickets online.
Update on June 2013:
Miami Heat survived luckily by having Ray Allen's 3-pt shot to tie with 5 seconds left and won the 6th game of the 2013 NBA Finals in overtime and successfully won back-to-back NBA Championship title. Hats off to Heat!
Update on September 2012:
Miami Heat will have championship ring and banner ceremony prior to Heat vs Boston Celtics on Oct 30. You cannot afford to miss once-in-lifetime moment! Shop now for Heat Opening Night tickets.
As for shopping for Heat tickets in Spanish, visit Boletos para Miami Heat.
2MoreTickets acts as an intermediary between buyers and ticket sellers (defined below) to facilitate the purchase and sale of NBA basketball tickets, and as such is not directly involved in the actual ticket sale transaction between the buyers and TICKET SELLERS. All sales are final. As tickets sold through this SITE are often obtained through the secondary market and prices are determined by the individual ticket seller, the prices for tickets may be above or below face value.

domain: sports


Product DNAArmour is the first thing you put on & the last thing you take off, every time you workout or compete。
- HeatGear® fabric is ultra-soft & smooth for extreme comfort with very little weight.
- Stretch-mesh back & underarm panels deliver strategic ventilation.
- 4-way stretch fabrication allows greater mobility in any direction.
- Moisture Transport System wicks sweat & dries fast.
- Anti-odor technology prevents the growth of odor causing microbes.
- Mesh panel on back neck with ARMOUR wordmark.
- Based on YL size, its weight shall be 78 g, varying with actual size.
- Fit guidelines


Pressure sprayer suitable for spraying plant care products and for different uses. Manufactured with top quality resins, it stands out for its excellent functionality, pressure resistance, strength and durability. The 360° version, thanks to a flexible deep tube allows a uniform and continuous spraying at any angle.
• adjustable jet with anti-theft ring
• 2 bar safety valve and pressure relief at the end of the use
• flexible dip tube
• valve that holds pressure for a long time
• stainless steel springs
• adjustable nozzle
• calibrated hole
• reinforced resin shaft
CERTIFICATIONS AND FEATURES
Watering can with 2 L. capacity and modern design. The careful study of weight distribution makes...
Watering can with 5 L. capacity and modern design. The careful study of weight distribution makes...


The Tesla Cybertruck might take on a slightly different shape when it actually comes to adapting it for road safety rules. We’re sure CEO Elon Musk will be able to pull off a genius move and sort this issue, but we can’t help but wonder if the impact of this interesting design will be toned down by any future modifications to allow it to drive on the public road.
Thankfully, architects and designers have been coming up with buildings that echo the all-electric truck’s design cues, so if it does become a little less individual later down the line, we can always take solace in the fantastic designs that have followed it. This specific design is called “disPlace”, and features a cyberpunk-looking building design located somewhere that looks fairly similar to Mars.
Unlike the Tesla truck, the building uses flowing lines and curves in its design, acting as a junkster position to the angular and straight vehicle. The two types of designs compliment each other perfectly with the house having details where the car has flat surfaces, but we do wonder, would this look better with a Roadster instead? You know what? I think we’ll get one of each Model, just to make it fair, right?


text: As the name suggests, I'm a mother of triplets (all boys) and recently a little girl. I love to knit, crochet, make jewellery and bake. My first introduction to crafting was knitting, a group of pensioners came to my school and taught us how to knit. we all made sqaures, which they sewed together and then sold for charity. Since then I've been knitting on and off but became serious about it in the last two years.Crochet came into my life when I was pregnant with my boys. I saw a collegue crocheting and wanted to know how to do it. So when I got home I looked at turorials online.I got into jewellery making in the same way, One of my work friends was making a necklace. Seeing that I was very curius about what she was doing, she gave me the full low down on the basic kit I would need to get started.Baking has always been apart of my life. I love baking but don't to do it so much. I'm waiting for my boys to get into school full time (they're three at the moment) then my oven will never be empty.

domain: artistic


text:
Although Zynga Inc (NASDAQ: ZNGA) reported third-quarter results ahead of expectations, the 2020 outlook reflected lower margins, which kept the stock’s uptrend in check, according to Bank of America.
BofA’s Ryan Gee maintained a Neutral rating on Zynga, reducing the price target from $6.70 to $6.60.
Zynga’s third-quarter bookings were around 3% higher than the Street expectations, driven mainly by Empires & Puzzles and Merge, while EBITDA was about 17% higher, Gee said in the note.
The company guided to fourth-quarter bookings 5% above the consensus estimate and its EBITDA guidance was also 17% better than expected.
Although Zynga maintained its outlook for low double-digit bookings growth in 2020, it projected a year-on-year decline in EBITDA margins, the analyst said.
The company’s outlook implies EBITDA of around $305 million in 2020, versus consensus expectations of $343 million, Gee noted. He further wrote, “We think the revised margin outlook for 2020 will likely keep a lid on estimates and overshadows what was otherwise a positive print.”
The analyst said, however, that margin expansion may not matter if the company’s top-line continues to grow.
Shares of Zynga were down 0.48% to $6.18 at the time of publishing on Thursday.
15 Most Popular Stocks Under , According To Robinhood Users
Latest Ratings for ZNGA
View More Analyst Ratings for ZNGA
View the Latest Analyst Ratings
See more from Benzinga
- Morgan Stanley Remains Steady On GE After Earnings Call
- Bank Of America Downgrades AMC, Citing Limited Catalysts
- Wells Fargo Turns Bullish On Revance Therapeutics After Meeting With Management
© 2019 Benzinga.com. Benzinga does not provide investment advice. All rights reserved.

domain: economics


text:
BAR HARBOR — A sneak peak of the Acadia Dance Festival will be available at the Jesup Memorial Library on Thursday, July 25, at 7 p.m.
The festival, which features performances by Nimbus Dance, will be at the Criterion Theatre on Saturday, July 27, at 8 p.m.
The preview at the Jesup is free and open to the public. Nimbus Artistic Director Samuel Pott and company dancers will perform excerpts from the dances that will be showcased during the festival. Pott will also discuss the company’s creative process and their work in community and youth engagement.


The southbound platform of the Mountlake Terrace Transit Centerís freeway station will be closed on Saturday and Sunday, Feb. 2 and 3, for construction. The closure affects Community Transitís Route 511 and Route 512 weekend commuter buses.
To travel south from Mountlake Terrace, Community Transit is advising Route 511 and 512 commuters to ride a northbound 511 or 512 bus to the Lynnwood Transit Center, then transfer to a southbound bus. For those wanting to disembark from a southbound 511 or 512 bus at Mountlake Terrace, Community Transit is advising riders to continue to the 145th freeway station, get off the bus there and transfer to a northbound bus, then disembark at Mountlake Terrace.
Community Transit reminds riders that there is no additional cost for transfers, but the closure will affect Mountlake Terrace travel times for Routes 511 and 512. The northbound freeway station at the Mountlake Terrace Transit Center will not be effect by the construction closure.
Fares on all Community Transit service are going up effective Feb. 1. Local bus fares will go up by 25 cents for all riders, increasing the adult fare to $2.00 and youth (ages 6-18) to $1.50. Commuter fares to King County from Everett and south Snohomish County, including from the Mountlake Terrace Transit Center, will go up 50 cents for adults and reduced fare customers, 25 cents for youth. A commuter fare will run $4 for adults, $3 for youth. Monthly passes will also see a hike in cost starting Friday.


text:
Volcano near Ankisabe, Madagascar. The beauty of this photo hides the soil and ecosystem degradation that has occurred in Madagascar over recent decades as a result of slash and burn agriculture techniques.
Madagascar Everything You Need To Know Before Traveling To The Island Of Lemurs.
I got home late last night from another trip to New York City (second on in two months! As fun as it is to go the every once in mind staying put for a little while either. :-) Anyway you look it is STRESSFUL! But one thing I did differently
A comprehensive infographic of the Kruger National Park of South Africa.
trip from Prague to Kutná Hora, one of the most charming towns in the Czech Republic
Day trip from Prague to Kutná Hora, Czech Republic | Tips what to do in Kutná Hora and how to get there from Prague without a tour | Visit stunning UNESCO site in the Czech Republic | Czech Republic Travel #kutnahora #czechrepublic


text:
Support for ue5 and ue4 skeletons.
The concept of a sports tournament knight, made in the style of ski-fi. It was inspired by the tournament froghelmet and wedge-shaped breastplate of the late Middle Ages. The concept has two chest options:
The first with dynamic neck protection and a wedge-shaped breastplate.
The second without neck protection and more ergonomic bib.
There are also 3 faces: African, Asian and European. And there is a simple face rig using bones.
Heavy/Light armor version:
There are 3 options for painting armor: Dark, White and Red.
Support for ue5 and ue4 skeletons. There are two sets of meshes for each skeleton respectively.
97 custom animations for ue4 skeleton and 97 custom animations for ue5 skeleton.
For custom animations, a skeletal sword mesh is used, which is connected to the character via set master pose component in the blueprint settings. Since the sword skeleton mesh has animations.
There is also a static version of the sword. Which joins the character on sockets. This variant is used in demo animations.
There are corresponding blueprints of characters.
There are 97 animations in total, but 34 of them are just transitional animations. (I wanted to create smooth transitions between the main animations so that the character moves seamlessly). I'm not sure if this is in demand, but I will be grateful for any feedback on this matter) All animations are shown and numbered in the video. The numbers in the video fully correspond to the numbers of the animations in the engine. There is also a diagram of all animations in pdf format with corresponding numbers.
Link to PDF file with animation tree


text:
With the UN Climate Change Conference in Katovice (COP24) now underway, the international community is discussing how to drastically reduce CO2emissions. Transport is a key factor, responsible for about a fifth of global CO2 emissions – and the trend is rising.
German technology company Graforce has developed a unique technology for producing climate-neutral, synthetic fuels from industrial wastewater and renewable energies. With low hydrogen production costs, a wide variety of wastewaters and significantly reduced emissions, its new plasmalysis technology makes a significant contribution to replacing fossil fuels.
“We are well below the climate targets agreed in Paris. It’s high time to seize every opportunity,” explains Dr Jens Hanke, founder of Graforce. “E-fuels could be critical to climate protection, especially in the transport sector.”
Graforce has been working on the future of energy supply since 2010. At its Power2X plant in Berlin, Graforce is already producing hydrogen using the plasmalysis process developed in-house. Unlike electrolysis, which uses distilled water, plasmalysis produces hydrogen from high-energy chemical compounds in wastewater. The process halves fuel production costs and results in significantly higher yields.
A high-frequency field of tension – called plasma – is generated from solar or wind energy above wastewater, which is produced, for example, in production processes in biogas, sewage or industrial plants. This plasma breaks down the carbon and nitrogen compounds (urea, amino acids, nitrates and ammonium) contained in the water into individual atoms, which then rebond. This produces hydrogen and – depending on the requirements – CO, CO2 or methane (CH4).
Synthetic liquid fuels can then be produced from the resulting CO2 or CO and hydrogen using the proven Fischer-Tropsch process. These fuels make, above all, long-haul transport, aviation and shipping more climate-friendly without any adjustments or restrictions.
Using methane or mixing hydrogen with biogas produces HCNG, which can be used as fuel in natural gas vehicles and in combined heat and power plants to reduce emissions (CO2, CO, HC, NOx) by 20% to 60%. The only waste products that remain are purified water and oxygen. Graforce cooperates with the carmaker Audi, the utility company Berliner Wasserbetriebe and other firms.

domain: chemistry


text:
Microbiome And Cancer Review Pdf
File Name: microbiome and cancer review .zip
The microbiome is the ecological community of commensal, symbiotic, and pathogenic microorganisms that share our body space 1.
- Gut Microbiota and Cancer: From Pathogenesis to Therapy
- The microbiome and lung cancer
- Gut microbiota, chemotherapy and the host: the influence of the gut microbiota on cancer treatment
- Microbiome and Breast Cancer: New Role for an Ancient Population
Gut Microbiota and Cancer: From Pathogenesis to Therapy
PLoS Pathog 13 9 : e This is an open access article distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Competing interests: The authors have declared that no competing interests exist. These hallmark capabilities have given us remarkable insight into the multistep changes that occur within the tissue microenvironment during cancer development. However, it has become well established that host-associated microbial communities, termed microbiota, also play integral roles in modulating various aspects of host physiology.
The microbiome and lung cancer
In the past decade, more cancer researchers have begun to understand the significance of cancer prevention, which has prompted a shift in the increasing body of scientific literature. An area of fascination and great potential is the human microbiome. That in mind, racial disparities with regard to colorectal cancer treatment and prevention are generally understudied despite higher incidence and mortality rates among Non-Hispanic Blacks compared to other racial and ethnic groups in the United States. A comprehension of ethnic differences with relation to colorectal cancer, dietary habits and the microbiome is a meritorious area of investigation. This review highlights literature that identifies and bridges the gap in understanding the role of the human microbiome in racial disparities across colorectal cancer. Herein, we explore the differences in the gut microbiota, common short chain fatty acids produced in abundance by microbes, and their association with racial differences in cancer acquisition. Core tip: In this paper, we summarize the literature in relation to the gut microbiome and colorectal cancer.
Gut microbiota, chemotherapy and the host: the influence of the gut microbiota on cancer treatment
Cancer is a multifactorial pathology and it represents the second leading cause of death worldwide. Conversely, several microbiota subpopulations may expand during pathological dysbiosis and therefore produce high levels of toxins capable, in turn, to trigger both inflammation and tumorigenesis. Importantly, gut microbiota can interact with the host either modulating directly the gut epithelium or the immune system. Numerous gut populating bacteria, called probiotics, have been identified as protective against the genesis of tumors. Given their capability of preserving gut homeostasis, probiotics are currently tested to help to fight dysbiosis in cancer patients subjected to chemotherapy and radiotherapy.
Microbiome and Breast Cancer: New Role for an Ancient Population
In the last decade, the role of microbiota-host interactions in driving human cancer plasticity and malignant progression has been well documented. Germ-free preclinical models provided an invaluable tool to demonstrate that the human microbiota can confer susceptibility to various types of cancer and can also modulate the host response to therapeutic treatments. Of interest, besides the detrimental effects of dysbiosis on cancer etiopathogenesis, specific microorganisms have been shown to exert protective activities against cancer growth.
We use an ecological lens to understand how microbes and cancer cells coevolve inside the ecosystems of our bodies. We describe how microbe-cancer cell interactions contribute to cancer progression, including cooperation between microbes and cancer cells. Microbiota influence many aspects of our health including our cancer risk. Since both microbes and cancer cells rely on incoming resources for their survival and replication, excess energy and nutrient input from the host can play a role in cancer initiation and progression. Certain microbes enhance cancer cell fitness by promoting proliferation and protecting cancer cells from the immune system. How diet influences these interactions remains largely unknown but recent evidence suggests a role for nutrients across the cancer continuum. Microbes play an important role in human health and disease, including influencing our cancer risk.
The analysis of microbiota composition has become routine in our time, mostly due to the explosion and availability of new technologies [metagenomic sequencing technologies that incorporate next-generation DNA sequencing methods with the computational approach of targeted 16S rRNA hypervariable regions or whole-genome shotgun sequence reads], that allow for the identification and classification of a great variety of microbial species 1 , 2. The genome of the microbiota is fold more extensive than the human genome 3. The distribution of microbial cells surpasses the number of all human cells, including somatic and germ cells throughout the human body Microbiota is a term that has been established as the sum of bacteria, fungi, parasites and viruses occupying the host 7. However, defects in the host regulatory circuits that control bacterial sensing and homeostasis, or alterations in the microbiome, through environmental changes infection, diet or lifestyle , may disrupt the symbiotic relationship and promote disease. Increasing evidence indicates a key role for bacterial microbiota in carcinogenesis 6 , 7 ,
PDF | The collection of microbes that live in and on the human body - the human microbiome - can impact on cancer initiation, progression, and.

domain: biology


text:
Guns N' Roses fan forum.
guns, roses, appetite, discussion, rose, music, bumblefoot, buckethead, slash, richard, fortus, tommy, stinson, duff, mckagan, izzy, stradlin, steven, adler, matt, sorum, gilby, clarke
This is the official No Life 'Til Metal & Metal Metropolis discussion board.
metal, thrash, heavy, speed, ultimatum, hirax, avenger, blood
THE place on the web to discover the best rock bands that proclaim the gospel of Jesus Christ!
christian, metal, christian, rock, christian, music, bible, study, skillet, kutless, narnia, whitecross, stryper, building, third, disciple, deliverance, crystavox, mission, guitars, titanic
Forum of Italo Maniacs ! Italo Disco Forever.
italo, disco, eurobeat, dance
This is for fans of Karl Wallinger and the band World party.
world, party, fans, this, karl, wallinger, band, world
Heavy Metal, Death Metal, Doom Metal. etc. Heavy Metal, Death Metal, Doom Metal. etc.
metal, never, bends, heavy, death, doom, metal..etc...
Several Species of Large Burly Trogs Gathered Together in a Cave and Grooving on the Doom (a.k.a. the official board of TROGLODYTE DAWN, the Vigilante Pariahs and other Stone Grooves)
troglodyte, dawn, trog, dawn, trogdawn, doom, ambient, metal, rock, cave, sanctuary, support
Rock Island is a forum for discussing rock, hard rock, heavy metal, Gothic, and many other types of music. We also discussed other topics such as sports, spirituality, entertainment, and many more.
heavy, metal, music, friends, sports, religion, spirituality, movies, entertainment, jokes, funny, pictures, videos, family, christianity, bible, baseball, basketball, football, discussion
Our gaming forums
free, forum, shadowrun, g.u.r.p.s
Eternal Art's Official Forum. Discuss different topics concerning the metal band Eternal Art.
eternal, band, official, forum, eternal, eternal, umeå, eternal, umea, eternal, forum, eternal, umeå, forum, eternal, umea, forum, metal
Lynch first, ask questions later.
death, wifom, lynch, questions
Free forum : We are EPOCH on the Rock a local St. John's LARP group, based on the rule system used by EPOCH Toronto.
epoch, rock, larp, roleplay, epoch, rock, john's, free, forum
The Church of the Divine and Venerated Saint Johnny Thunders, the Patron Saint of Rock 'N' Roll
johnny, thunders, york, dolls, city, forum, punk, jerry, nolan, walter, lure, waldo, richard, hell, waldos, heartbreakers
Death metal, thrash metal. NIHILISTIC HOLOCAUST Board (Not for sale)
school, death, metal, thrash, tape, trading, fanzine, xerox, vynil, vinyl, distro, label, grindcore, cassette
Kamiki Aya (24 years old) is known for her liquid, powerful vocals and roots in pop rock and punk music. 2006 were the year of her revelation thanks to her 2nd single Pierrot and her first full album
kamiki, happy, now?, secret, kamiki, secret, code, jpop, jrock, fansite, ashita, tame, kaming, kamen, rider, pierrot, lyrics, kera, w-b-x, boiled, extreme, avex, trax, international, evilalive, gloriosa, a-nation
The No. 1 place on the net to discuss (hed)p. e. Featuring, tour dates, interviews, music, videos lyrics and more!
lyrics, (hed)pe, planet, earth, p.e., forum, jahred, world, orphans, discussion, bartender, suffa, jaxon, benge, suburban, noize, records
[FMJ] Full Metal Jacket, Based in Multiplayer Games.
[fmj], full, metal, jacket, team, [fmj], full, metal, jacket, based, multiplayer, games
Forum za sve fanove Toma i Billa Kaulitza!
kaulitz, twins, serbia, fanove, toma, billa, kaulitza!
Are you Sharon Obsessed And Proud? This is the place for you.
free, forum, soap, sharon, obsessed, proud?, this
We strike hard
zambezi, mambas, strike, hard
Free forum : A forum about The Beatles. Free forum : Hard Days Night
free, hard, days, night, about, beatles
forum svih kolekcionara svijeta
kolekcije, ulaznica!, svih, kolekcionara, svijeta
orangerange power!!. The Orange Range Forum. orange range forum
Forum for Red Rock Raiders gild in Glory of Fellowland game
rock, raiders, forum, gild, glory, fellowland, game
forever yours ;*
free, forum, fashion, stars, forever, yours
free, rock, your, rawr
Free forum : Welcome! This forum is for all TH lovers to obsess, ]
free, tokio, hotel

domain: entertainment


text:
Have pre-sale questions? Sure, get in touch
If you have any query or wish to talk to us, please free to get in touch with us. Fill the below form to help us with your contact information.
Your Financial Business will stand out from our extensive list of finance professionals.
You can nominate your financial firm via our Contact Form and get a chance to attract more unique visitors around you who are looking for financial services.
Copyrights © 2020 FinanceAwards.org. All Rights Reserved.


text:
THE KM TOOLS
NON-IT METHODS IT METHODS
after action reviews
collaborative physical workspace
community of practice
social network services
KNOWLEDGE MANAGEMENT PROCESSES
Locate: audit, mapping
Acquire: audio, recording, video
Refine: community of practices, assessment, experts
Organize: content management, taxonomy
Share: wikis, conferences
Apply: decision making, help desks, workflow
MY RESEARCH QUESTION
What are the cultural differences between older and
younger members in a non-profit organization, in relation to
their knowledge values and approaches to knowledge
acquisition, sharing and use, and how are these
accommodated in the organization?
in simpler words…
What are the differences between older and younger generation?
Are they complimentary or competitive?
How can KM help?
younger generation older generation
THE WAVES OF DIFFERENT
• the FIRST wave (1970’s & 80’OLD
s, 50 yrs old- above)
• the SECOND wave (1990’s, 40’s)
• the THIRD wave (2000’s, 30’YOUNG
• the FOURTH wave (2010’s, 20’s)
MY CASE STUDY PROFILE
Organization: Translators Association of the Philippines (a nonprofit)
Year founded: 1974 (from 15-75 current members)
Core Mission: empowerment of the indigenous/minority people through
1. community development
4. literacy and
5. scripture translation
a tribe from Ifugao
TAP’s target communities
Philippine Population: almost 100,000
Major languages: 8
Minor languages: around150
40% of the population are indigenous
MY MAJOR FINDINGS
• knowledge sharing mechanisms (formal and informal)
• knowledge sharing motivation
• knowledge sharing barriers
• different perception about knowledge values between older and
• the role of personal initiative and leadership in knowledge management
• the importance of empowering people
• best practices in creating a healthy knowledge sharing culture
just one of my major
4 FACTORS CONTRIBUTING TO
• Technological Advancement
• Change of Organizational Strategy
• Change of Trend in Collaboration
• Different Knowledge Values
from 25 years to 10 years of
CHANGE OF ORGANIZATIONAL STRATEGY
-from lone rangers to
becoming project managers
CHANGE OF TREND IN COLLABORATION
-they collaborated in many different ways with their partner
one of the processes in Knowledge Management
Why capture knowledge?
-to share, develop, use, store
Questions to consider when capturing knowledge
1. What is the primary purpose ?
2. What kind of knowledge?
3. What is the best way to capture?
4. How to utilize the knowledge that you capture?
5. How to properly store it?
HOW DO I APPLY KM?
As a starter:
You can be a Knowledge Champion
“Catch the idea and share it.”
contact me: email@example.com
personal website: www.joanhope.com

domain: sociology


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Entertainment News Leaders ©
Las Vegas was brimming over with super-hotties as the Club SI Swimsuit shindig rolled into town last night (February 16).
And beautiful babes like cover girl Kate Upton, Irina Shayk, and Anne V all worked their magic for the cameras outside Pure Nightclub at Caesar’s Palace.
Photo Credit: Getty Images
Though it’s the dead of winter, New York City was super hot last night (February 14) thanks to the 2012 Sports Illustrated Swimsuit Issue launch.
The big event was held at Crimson NYC and 2012 cover girl Kate Upton was all about celebrating her massive achievement just one year after her ‘rookie’ status.
Photo Credit: Getty Images, Wenn.com


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Ludwig Ambassador Deluxe Tenor Banjo On Sale
Made in Chicago circa 1920's. American black walnut, gold plated and engraved, heavily inlaid resonator, original hardware, Planet tuners with solid pearl buttons, engraved tailpiece, external action adjuster. Some wear to the original finish otherwise superb. Supplied with its original silk lined case, which still has its enternal badge in place.
Very rare in this condition. Was £1600 now £1200 Photos
Ludwig Cort Tenor Banjo
American black walnut, new finish and plating, original hardware. Stunning condition. HSC. £1000. Photos


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Country music entertainer and native Missourian Leona Williams had a stretch of U.S. Route 63 named in her honor Sunday in a private dedication ceremony. The newly christened “Leona Williams Highway” runs through the singer/songwriter’s hometown of Vienna, Mo.
To celebrate the occasion, Leona Williams and her son, Ron Williams, gave a public concert at the Vienna High School gymnasium following the dedication ceremony.
“I never dreamed I’d have a highway named after me,” Williams said. “I’m honored and thankful to receive such an honor. I want to credit my family and friends and the folks in Vienna for thinking so highly of me.”
Active in her family’s band since childhood, Williams landed her first radio show, “Leona Sings” on KWOS Radio in Jefferson City at the age of 15. Later, she worked as a bass guitarist and backing vocalist in Loretta Lynn’s road band. By 1968, Williams was recording for Hickory Records, where she released several singles, including: “Once More” and “Country Girl with Hot Pants On.”
In 1976, she recorded the album San Quentin’s First Lady for MCA Records, which was the first country album recorded by a female artist inside a prison. She joined Merle Haggard’s road band in the mid-1970s, where she wrote two of Haggard’s No. 1 hits, “Someday When Things Are Good,” and “You Take Me For Granted.” In 1978, the two charted in the country Top Ten with the song, “The Bull and the Beaver.”
She also wrote “Dallas” for Connie Smith and “Get Whatcha Got And Go” for Loretta Lynn. She recorded two more singles for Elektra Records in 1981, and charted another duet with Haggard titled, “We’re Strangers Again.”
In 1999, she was inducted into the Country Music Association of Texas Hall of Fame. She was honored with the prestigious George D. Hay Award in 2002 and was also inducted into the Missouri Country Music Hall of Fame. In 2011, Williams received the Entertainer of the Year Award by Reunion of Professional Entertainers. For the better part of the last decade, she has been headlining some of Branson’s most successful shows.

domain: celebrity


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Leo says a good way to do this is to create a gmail account for them, and just email photos to it. Then later in life, he can give them access to the account and they can see all their baby pictures. He could also use Facebook's timeline feature, and upload photos to that. The only problem with this is that Facebook requires users to be at least 13, so he'd have to lie to Facebook to create an account for them. Leo says there are sites specifically for this type of thing, but they aren't nearly as likely to stick around as Facebook and Google will.
Michael Horowitz, author of Computer World's blog "Defensive Computing," has an interesting article called "Google knows nearly every Wi-Fi password in the world." If true, it wouldn't take much for the NSA or some other law enforcement division to get your Wi-Fi password and have access to your computer without a warrant.
A new report indicates that Google may actually have access to Wi-Fi passwords used by every Android user. Whenever a user signs into a new Android device, they enter their Google credentials. Then, Google can find your Wi-Fi network and join it automatically. This can only be done if your Wi-Fi password had been uploaded to Google. Leo says it's convenient, but after all of the news about the NSA surveillance, this is a bit scary too.
Dave is curious about Google Voice, which is being rolled out in Canada. Leo says that Google Voice was originally called Grand Central and was designed to be a cloud based PBX system that could route calls to various phones and voicemail. He could also put a Google Voice app on his smartphone, which would allows him to bypass text message charges. He can also use this to make phone calls. Best of all, it's free!
Google has bought Bump for an undisclosed price, though Leo suspects it's around $100 million. Bump is cool app where you transfer information from one phone to another with a simple "tap" of smartphones. Leo says that the app isn't really needed by Google, but they're after the developers and engineers themselves. That shows how profitable getting into app development can be. Look at Instagram, for example.
Dave has thousands of pictures, and he would like to organize them in a more sensible way. Leo says that Google Picasa will organize them by date, but he can also create folders by events and password protect them so he can share them with others securely. Picasa will automatically propagate it online. It also has face recognition so that it's easy to find all pictures of an individual. He can even geo tag and organize them.
Richard bought a new Google Nexus 7 and he's wondering what to do with it. Leo says it's a great content consumption device, including reading ebooks, watching movies, listening to music, surfing the internet, sharing on Facebook, and writing emails. Leo says the first thing to do is create or log into a GMail account. That single sign in will do everything on Google for him.
Richard is concerned that Google will read his email and use his activity for advertising. Leo says that Google only has computers read email, and it does this to filter spam. No human is reading through emails.
The clause that Google will use his activity to advertise means that Google will search his email for keywords, like it does spam filtering, and will customize ads on his page based on that activity. So it's for stuff he could use. It's important to note that nearly every other ISP and service does this as well. And he's getting gmail for free.
Breaking tradition of naming their Android flavors after generic desserts, Google has made a deal with Nestle to name their next version of Android "KitKat." Google claims there's no money changing hands, but there is word that promotional consideration will be done on the part of Nestle.
Android 4.4 will be named "Kit-Kat". Google has been naming all of their Android operating systems after desserts, like "Cupcake," "Donut," "Froyo," etc. It's all been generic dessert names, though, until now. There also will be a new Google Nexus phone that Leo guesses will be out in the new few weeks.


Two more Service Module tests
As NASA Orion Program Manager Mark Kirasich put it when the ESM arrived at KSC in November, “What we’re going to do now and what we’ll keep doing for the next several months is ‘integrate and test’ and ‘integrate and test’ to make sure that these vehicles function well together.”
More specifically Schneider said: “We basically build the vehicle up to a level that matches the next test configuration.” “There’s a lot of internal components tanks and avionics boxes and things that are inside the CMA, inside the outer mold line of the Service Module,” Wilson added. “I think for the most part we’re done.”
Once functional testing is complete, the Service Module will have two more standalone tests. The first is a thermal cycle test.
In addition to all the operational wiring and sensors packing into the spacecraft, this first working Service Module has a significant amount of development flight instrumentation (DFI) installed. “DFI is probably one of the biggest challenges we have, there’s so much of it,” Schneider said.
“I forget how many data acquisition units we have on the spacecraft, but I think it’s somewhere between six and eight, maybe even more and you need all that because there’s so much information being gathered by the instrumentation that you can only get like a fraction of it in the telemetry during the flight. The rest of it is all going to data acquisition units and stored onboard the CM and after the CM is recovered all that data is downloaded, pulled off those data acquisition units.”
“One of the other challenges with DFI is you usually don’t quite know where to put it until all the other systems are fully designed so it’s typically one of the last things to be designed and so that’s always a challenge you know when you’re trying to put those systems in, and kind of find the right places for them in the end,” Wilson added.
There’s even more instrumentation for ground tests like the thermal cycle test. “So you have GTI, which is ground test instrumentation, which is instrumentation that you need to get data during these tests. It’s not going to fly, so most of it comes off before we fly but some of the GTI is buried so you can’t get it off,” Schneider noted.
“So you have to put it on as if it were going to fly and then you just abandon it after you get the data from the test.”
“Once we get out of all the initial power up and the functional tests we’ll go into [an] oven basically,” Wilson added. “We’ll cook and cool it and that GTI is what tells us how it’s performing during those tests.”
Following the thermal cycle test, the Service Module will be reconfigured for a direct field acoustic test (DFAT). For this ‘integrate and test’ cycle, most of the remaining, large appendages will be attached including the four solar array wings.
“I think the biggest scope yet to go with the ESM is the solar array integration, that’s a huge amount of work and they’re not on yet,” Schneider said.
“The Dutch Airbus guys show up, you know those are the guys that build it, they do a manual deploy just to check for damage during shipment and we do a soft-mate to the Service Module and do a deployment that way, driven by the spacecraft, and then we actually physically install them after we do that second deployment test.”In addition, the nozzle for the OMS-E engine and the spacecraft adapter (SA) will be installed at the base of the ESM for the DFAT. The test will validate that the working, integrated module handles high-noise levels within requirements and remains healthy.
The solar array wings and the spacecraft adapter are then removed and the Service Module is prepared for mating to the Crew Module. The OMS nozzle will remain on the spacecraft.
Crew Module status
While the Service Module integration and test activities were going on, a couple of remaining major components for the EM-1 Crew Module arrived recently and were installed. At the time the ESM arrived at KSC in November, a few of the CM avionics boxes were still being reworked and the first working side hatch was due from its vendor.
“All the avionics are back in, we’ve actually done all of the regression testing associated with putting them back in, we’re finished with that,” Schneider noted. “We’re integrating the hatch as we speak, the side hatch integration should be complete next week,” he added.
The Crew Module was largely outfitted with those exceptions. Functional testing and a thermal cycle test were completed by the end of 2017 over a year ago and the heatshield was installed last summer. While waiting for ESM arrival and Service Module integration, issues with a few systems such as a few avionics boxes were addressed.
Now that all of the components are on-site, the Crew Module is being prepared for its last standalone test. “The Crew Module goes through a direct field acoustic test as well, it’s already been through its thermal cycle test,” Schneider noted.
“So we have to get it configured for the direct field test, which means we have to install the backshell panels temporarily and the forward bay cover. After we put the hatch on, we’re basically we’ve got a few ‘cats and dogs’ things to clean up but then mainly what we’re doing is getting it configured for the acoustics test.”
Another one of those cats and dogs is to install the docking hatch plate. After the DFAT is complete, the Crew Module will be prepared for mating to the Service Module.
A silicone-oxide coated aluminum kapton tape to prevent electrostatic discharge will be applied to the thermal protection system tiles on the backshell panels. For the EFT-1 flight, the tape covered the heatshield but not the backshell tiles.
One panel was recently taped to verify the first-time application procedures, but the remainder will be covered after the DFAT.
Once the remaining standalone tests are complete, the modules will be mated at the far end of the O&C Building. “The cell in the building that we do that work in we call the FAST (Final Assembly System Test) cell and the schedule has us in there for about eight weeks doing the CM to SM mate, but it’s not just the mate,” Schneider said.
The Service Module will be moved into the cell and then the Crew Module will be brought over and lifted on top on to join the two. “By the way, it’s the same exact location that the Apollo program used to stack the Command Module and their Service Module and a couple of the other elements that they used,” he noted.
As Schneider observed earlier, the spacecraft is often being configured for its next set of tests, which will be a series at Plum Brook Station in Ohio later this year. In this case, getting the combined Crew and Service Module (CSM) ready for the space environment tests at Plum Brook will also configure some parts of the spacecraft for launch.
“The schedule has us in there for about eight weeks doing the CM to SM mate, but it’s not just the mate,” he explained. “The umbilical that runs between the CM and SM, you can’t put that on until you have a CM and an SM together, so again it’s bunch of that kind of stuff.”
“We put the backshell panels on I believe for flight in there, which means we have to do all the thermal barrier closeouts,” he added. “A lot of thermal barrier, MLI closeouts happen in that eight weeks because you’re really getting the vehicle buttoned up for flight.”
Schneider noted that all the functional testing on the Crew Module and Service Module before they are joined limits the testing necessary post-mate. “We try and test as much as we can at the module level and so by the time we get to the FAST cell the only things that we really need to test are the new interfaces,” he said.
“So anything that crosses the CM-SM interface we would test there, but we don’t do a lot of retesting of all the stuff that we tested at the module level, we just test the stuff across the interface, so umbilical tests or anything running across the umbilical or CM-SM R&R (Retention and Release) mechanism, those kinds of things are what we would test in the FAST cell.”
“We’ll do a high-level, general functional test prior to shipment to Plum Brook and then we’ll do the same thing after receive up there,” Wilson added.
Plum Brook testing later in the year
The combined Crew and Service Module (CSM) will be transported to Plum Brook for thermal vacuum (TVAC) and electromagnetic interference/compatibility (EMI/EMC) testing. The spacecraft will be powered for the tests.
“One of the things you want to do in the first thermal vacuum cycle we call it a thermal balance test and the idea is to figure out the equilibrium point of the spacecraft thermally and then you’re going to run the spacecraft itself because it’s both generating heat and radiating it at the same time so you want to make sure those systems are working,” Wilson explained.
Without its solar array wings, the spacecraft’s power distribution system will get its power generation from the EGSE used at Kennedy. “That same ground support equipment that we use at KSC in the O&C to simulate the solar arrays like the way we are during the power-on testing right now, we’ll use that same rack of equipment up there and it basically simulates the power generation of the solar arrays and feeds it into the same connections on the spacecraft,” Wilson said.
“We have to run the active thermal control loops while we’re in there so all that stuff that we have here, we move to Plum Brook with the vehicle,” Schneider also noted.
Final steps before launch preparations
Orion and its associated ground support hardware will be transported back to KSC after the Plum Brook tests, where Lockheed Martin will install the remainder of the CSM hardware and closeout the spacecraft for launch.
In addition to the solar array wings and spacecraft adapter, the Service Module launch fairings will be installed. “They’re one of the last things we do because you’re closing out the access to the Service Module,” Schneider said. “So after the solar arrays get put back on after Plum Brook for flight, the last time, then we put the fairings on that encapsulate the Service Module.”
Lockheed Martin will then turn the spacecraft over in the O&C Building to EGS for launch processing.


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domain: hobby


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sparkling bubbly flavoring
These Flavoring Elixirs can be placed in Frosting, Cakes, Cupcakes, Royal Icing, Pancakes, Waffles, French toast, Smoothies, Shakes, Fillings & Ganache.
ALL FDA regulated/2 year shelf life/Gluten Free/Vegan Friendly/Sugar Free/Artificial Colors
Use 1 & 1/2 tsp per cake mix/batter and or frosting to taste.
If you love lemon, use 2 tsp and or 1 tablespoon in your batter/mix.
Velvet Red use one TABLESPOON per batch/mix.
SPARKLING BUBBLY: This flavor is powerful! It gives a hint of bubblegum also!


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Rubbzy 100 pc Tie Dye /Glow in the Dark Rubber Bands w/ Connectors
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(Looms sold separately)
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- 100 x Rubbzy Tie Dye Glow in the Dark- Pink, Purple, Blue, Green, and Yellow
- 4 x Connectors