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Substance Abuse Treatment Centers Atlantic City NJ
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Substance Abuse Treatment Centers Atlantic City NJ: Overview of Substance Abuse and Healthcare Costs
According to the reports of National Institute of Drug Abuse, National Center on Addiction and Substance Abuse and Office of National Drug Control Policy, drug, alcohol and tobacco abuse are the major drivers of spending on healthcare sectors. Approximately 58% of all drug, alcohol and tobacco abuse costs paid by the federal and state government have been attributed to healthcare costs. You should consider this factor when it comes to In House Drug Rehab Centers Atlantic City NJ.
It is amounting more than $130 billion for tobacco, $25 billion for alcohol and $11 for illicit drugs in the United States whereas the approximate 2% of these figures are spent directly for the treatment of this kind of issues. Undoubtedly, the consumption of tobacco, illicit drug and alcohol is quite expensive in the United States exacting over $700 billion every year related to healthcare, lost work productivity and even crime. The indirect spending occurs due to medical costs of health or cognitive issues such as illness, increased disease frequency and the problematic lifestyle. Not so many people know this information when it comes to choosing the top Substance Abuse Treatment Centers Atlantic City NJ.
Most people overlook this information when they decide to go for Inpatient Drug And Alcohol Rehab Atlantic City NJ. The objective of this article is to give an overview of substance consumption and healthcare costs. The numbers of patients in this substance use are a varied group including those people who abuse only drugs or only alcohol and those people who consume both. Moreover, the severity level of the case is typically different that can be characterized as less severe addiction as abuse and more severe addiction as dependence. However, the term ‘substance abuse’ covers both cases together. In this respect, you will come to find out that while the relentless use of substance abuse is influencing the use of healthcare, on the other hand both the alcohol and drug taking are leading to higher healthcare cost.
Finding the top Substance Abuse Treatment Centers Atlantic City NJ could be really challenging. In the enhancement of healthcare expenditure, one of the most important contributors is the higher rates of physical as well as mental illness among those individuals who are completely addicted to drugs or alcohols. More they fall ill, more they lead the cost of their healthcare spending. Compared to the normal persons, substance abuse individuals use expensive acute care. Different studies conducted on the effect on the healthcare costs show that people who are suffering from this problem and any chronic illness such as diabetes, asthma or cardiovascular disease are less caring to follow adequate self-care practices and as a result, they receive inferior quality of care compared to those persons who are suffering from the same illness.
If you treat this health issue successfully, you can definitely eliminate your costs. But the cost difference between the individuals including and excluding the substance abuse disorder may not be eliminated completely. However, in this regard, more study is required to determine the long-enduring impact of abuse treatment and its healthcare costs. But it has been noticed that by investing in health centers, costs for these treatment can eliminate the costs of other social factors. For instance, by investing on the treatment, affected individuals can eliminate the cost related to arrest, criminal justice and incarnations. After all, the substance abuse and healthcare costs also improve the employability in the nation that leads to higher income for those who get rid of any cognitive related disorders. Now, you should be able to look for the best Substance Abuse Treatment Centers Atlantic City NJ.
Substance Abuse Treatment Facility Locator Atlantic City NJ (855-401-7967) | #1 Rated!
Substance Abuse Counselor Atlantic City NJ (855-401-7967) | #1 Rated!
Substance Abuse Treatment Centers Atlantic City NJ: Golden Tips!
Nutrition and Rehabilitation: Against common perception, a rigorous cardiovascular exercise regime is not as effective in helping people shed pounds. Research proves that high intensity interval training is more effective in burning the extra fats and is recommended instead of endurance training. Additionally, most people do not like to pursue weight lifting as they do not like the bulky appearance. However, weight lifting is beneficial in toning your muscles, which will help in shedding the extra pounds. When you are lifting weights, you must not focus on isolation workouts but rather adopt challenging weights for the entire body with minimum rest periods between the various movements.
Weight Loss after Rehabilitation: Omelets served with a side salad offer light, tasty and filling meals. Omelets can be filled with mushrooms, cheese or prawns. A green salad without a dressing is preferable unless you limit yourself to a small quantity of home made dressing.
Several Health Issues due to Substance Abuse: Physical Injuries: If you look for the statistics of typical heath issues due to substance abuse, you will come to know that more illness, disabilities and deaths occurred due to substance abuse than from other avertable health condition. At present, one in the four deaths happens due to illicit drug abuse. People, who are addicted to substance abuse, are more likely to face unintentional injuries, domestic violence, risks of accidents, medical problems and even death.
Overcome Alcoholism at Home: Eat healthy food and exercise regularly- Lifestyle changes go a long way in helping you to recover from alcohol addiction. Fresh fruit and vegetable juices are healthy substitutes for alcohol and can be consumed in any quantity. They detoxify the body. Exercise or physical activity can be done at home in the form of yoga and pilates. Physical activity can help you to turn your attention from negative urges and stress to something positive. Your mind is liberated from the repetitive thoughts about your condition.
Help Someone Quit Drinking: Never be judgmental- You can never fully know what is going on in the mind of another person. You need to be compassionate and willing to understand his or her problem. You should never judge the person on the basis of his actions because you do not know what has led them to become dependent on alcohol. If you make an alcoholic feel shameful for his actions will only make him more dependent on the addiction to overcome the shame. You need to be patient and understanding.
Several Health Issues due to Substance Abuse: Effects on the Brain – In most of the people, it has been seen that their substance abuse leads them to mental illness. The chemicals of drugs affect the brain and nervous system in such as a way that they suffer from different mental issues.
Nutrition Tips after Drug Recovery: Do you know that there are many foods in the world that burn fat? Yes that is right, and this article will help give you insight into the top foods that burn fat so you can add them to your diet.
Nutrition Tips after Drug Recovery: fat burning workouts take time till you see real results. Do not hurry after unhealthy pills to lose weight quickly. Rather, stick to healthy eating and doing exercise is the best idea to lose weight.
Rehabilitation and Exercises: Figure-conscious individuals often find themselves striving to have hard cores. Literally they work themselves out to burn those belly fats and gain abdominal muscles for better health and a dreamy body. However many tend to overdo six pack abs exercises resulting to permanent injuries and adverse effect. The serious weight-conscious folks would have to be cautious about their strategy to avoid being invalid.

domain: medical


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Separate names with a comma.
Discussion in 'What Breed Or Gender is This?' started by polkachick, Jun 24, 2016.
Pullet. A cockerel would have a much redder, and more developed comb by that age.
Thank you. I was concerned she was a roo because she has some shiny green on some feathers.
That's just what happens when light hits black feathers just right.
This broody hen with chicks has that green sheen to her wing feathers.
And my Easter Egger, Margrett gleams with green, blue, and purple.
So cute such a happy mama.

domain: pet


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Beyonce's 'hard-up' father Mathew Knowles succeeds in getting child support payments to son slashed... as it emerges he skipped another month of payments
He earned millions from his days as Beyonce's manager.
But Mathew Knowles has succeeded in getting his child support payment slashed due to his dwindling income.
The legal maneuver came as it emerged he had skipped yet another month of payments to Alexsandra Wright, the mother of his four-year-old son Nixon.
Legal victory: Mathew Knowles, seen here with daughter Beyonce, has succeeded in getting his child support payment amount slashed
According to TMZ, he claimed in court he pulled in $127K in 2013, a far cry from the $3M a year he earned as his daughter's manager.
He also claimed that while income is vastly reduced he still has sizable expenses of $51,000 a month, and he is having to liquid assets to make up the shortfall.
A family court judge decided to reduce his child support to $2,485 a month.
According to child support records seen by Radar, Knowles owes $44,289.32 as of March 1, which has caused the State of California to prepare preparing to file contempt charges.
An insider said: 'The state’s file is mostly prepared. He has now been served with several documents regarding cases being opened from various agencies.'
Fatherless child: Alexsandra Wright previously revealed he had not even bothered to meet his four-year-old son Nixon
Before the split: Mathew with his superstar daughter (he used to be her manager, too) her sister Solange and his former wife of 31 years, Tina
Alexsandra laid into him during a TV interview last month, claiming he had never even met his son, telling Inside Edition's Jim Moret: 'You've seen more of my son than he has.'
It previously emerged she was using 'food stamps to survive' after it was revealed he owed $32,135,90 in child support.
At the time he slammed reports that he owed money, with sources close to the music manager told claiming messed up paperwork was to blame for the dispute.
In 2009, Beyonce's mother Tina filed
for divorce from Mathew after he reportedly had an affair with
Alexsandra, who fell pregnant and requested a paternity test.
Beyonce, 32, and sister Solange, 27,
didn't attend their father's wedding when he re-married earlier this
year, tying the knot with former model Gena Charmaine Avery in Houston,
Texas in June.
himself: Beyonce Knowles' father Matthew has hit back at claims that
he's a deadbeat father after falling behind on support payments for
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domain: celebrity


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You may know after finishing the Recipe:
After finishing this recipe you will be able to make an amazing colorful tea perfectly.
Why you may choose Herbalife Tea Bomb Recipe:
In your everyday life, you can boost your energy with this Herbalife Tea Bomb Recipe.
It is unexpectedly easy to make a healthy drink like Herbalife tea bomb at home in a very short time. It is also very much helpful for people who want to be fit and healthy.
It keeps you hydrated all day. So just choose this recipe and make a healthy tea.
Herbalife Tea Bomb Recipe and Nutrition facts
Herbalife Tea Bomb Recipe
It is surprisingly easy to make a healthy drink like Herbalife tea bomb at home in a very short time. Which will make your family happy and help keep the body healthy.
- Prep Time10 min
- Perform Time20 min
- Total Time30 min
- Serving Size1
- Energy5 cal
Ingredients of Herbalife Tea Bomb Recipe
- 1 pomegranate liftoff
- ½ tsp raspberry tea concentrate
- ½ oz aloe
- Hot required amount
- ½ cup cold water
- ½ cup ice cubes
- 1 pump sugar free red cherry syrup
- Blue food color (optional)
Instructions for Herbalife Tea Bomb Recipe
First heat water. Keep pomegranate liftoff into the shaker cup. Then pour ¼ cup hot water in the shaker cup and shake so the liftoff mixes properly. Let it rest to cool.
Then add raspberry tea concentrate and aloe into the cold liftoff mix. Interblent the ingredients with a spoon.
Fill 1/3 of the shot glass or glass mug with ice cubes. Then pour the mixture into the glass.
Mix the red cherry syrup in a shaker cup with 1/3 cup of water. Then confer it on top of the shot glass mixture.
Pour a little amount of water to fill the shot glass. Then drop 1-2 drops of food color and mix the upper portion carefully.
Finally drink Herbalife tea with a straw.
- 5 servings per container
- Serving Size1
- Amount per serving
- % Daily Value*Standard DV
- Total Fat0 g78 g0%
- Saturated Fat0 g20 g0%
- Trans Fat0 g
- Polyunsaturated Fat0 g
- Monounsaturated Fat0 g
- Cholesterol0 mg300 mg0%
- Sodium0 mg2300 mg0%
- Total Carbohydrate5 g275 g1.82%
- Dietary Fiber0 g28 g0%
- Total Sugars0 g
- Protein0 g50 g0%
- Vitamin D (Cholecalciferol)0 IU800 IU0%
- Calcium0 mg1300 mg0%
- Iron0 mg18 mg0%
- Potassium0 mg4700 mg0%
- Vitamin A0 mcg900 mcg0%
- Vitamin C (Ascorbic Acid)0 mg90 mg0%
- Vitamin E (Tocopherol)0 IU33 IU0%
- Vitamin K0 mcg120 mcg0%
- Vitamin B1 (Thiamin)0 mg1.2 mg0%
- Vitamin B2 (Riboflavin)0 mg1.3 mg0%
- Vitamin B3 (Niacin)0 mg16 mg0%
- Vitamin B6 (Pyridoxine)0 mg1.7 mg0%
Activity Needed to Burn:
05 calories (Total Serving)
1 minute 30 second
* Note: It depends on your activity, so it may be a little more or less.
Some questions about Herbalife Tea are answered below
How healthy are tea bombs?
- Since Tea Bomb has a lot of antioxidant properties, it helps to reduce blood pressure and maintain good heart health.
Can I drink Herbalife tea on empty stomach?
- It is usually better to have a 3 hour interval between drinking Herbalife tea and eating a normal meal. Because if you drink Herbalife tea and take a normal meal, there is a possibility of weight gain
Is Herbalife tea Keto friendly?
- Since it contains fructose and maltodextrin, it is in conflict with this diet.
Why Herbalife is bad for you?
- In some cases, herbalife products contribute to bacterial growth, and over supplements have been linked to liver damage.
What tea is good to lose belly fat?
- There are several types of tea that help reduce belly fat, such as: Oolong Tea, Green Tea, Herbal Tea, Puerh Tea.

domain: food


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El Paso is expecting beautiful weather Saturday before back-to-back windy days return to the forecast.
There is a cold front that is expected Tuesday going into Wednesday, dropping afternoon highs to the upper 60s.
As a cold front tracks our way, we expect below wind advisory level winds Sunday through Monday (15-25mph), before we see a possible high wind event Tuesday (30-40 mph).
Before the cold front arrives, we are expecting upper 80s as our afternoon highs this weekend and into the beginning of next week.
Calmer weather is expected at the end of next week.
Stay safe and weather aware with KTSM 9 News on air and online.
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- FALSE: Viral tweet about Gov. Abbott’s office, money offer to shooting victim’s uncle was lie

domain: news


Hey guys, what is going on, Chris Sajnog here, retired Navy Seal and founder of the SEAL training system. In this post, I want to teach you pistol aiming tips on why sight alignment is more critical than trigger control. Now let’s go ahead and get started.
One of the most interesting debates that I see going on online is the debate between what’s more important, trigger control or is it sight alignment? I believe and I hope to show you with some evidence here that sight alignment is always going to be more important than trigger control.
The best way I can explain this trigger control is to imagine you had a pistol pointed nowhere near your desired target. And you say, “I’m going to caress this trigger so perfectly, it will make me hit my target.” But of course, you miss.
How can that be? You practiced perfect trigger control. You manipulated that trigger so nicely. Well, the reason you missed is that your sights were not aimed at your target properly.
The best way that I can explain this pistol aiming tips about sight alignment is to imagine you put your gun in a vise and crank down the vise. So no matter what happens, those sights cannot move.
Now with your sight perfectly aligned, you could take a stick from 10 feet away and just poke at the trigger until the gun goes bang. Because these sights are perfectly aligned, and they’re not moving, I am going to hit my target.
Proper Sight Alignment
With trigger manipulation, you will miss your target. With proper sight alignment, you can do whatever you want to that trigger, but you will hit your target. What matters is that your sights are aligned.
Let’s say, as you pull the trigger, your gun moves for whatever reason. So as you press back, the gun is moving, and your sights become unaligned.
As soon as your sights become unaligned, you have a much less likely chance of hitting your target. So it doesn’t matter whether it’s from your trigger finger or from any other reason, your grip, what’s important is your sight alignment.
How to Pull the Trigger?
I teach people how to pull the trigger with their eyes. It may sound kind of silly at first, but what I mean is when I’m going to shoot, I am using my eyes, obviously, to make sure that my sights are aligned.
I’ve trained so much that my eyes are subconsciously telling my mind. “Alright, the sights are perfectly aligned.” When my mind hears that, it subconsciously tells my finger that it’s safe to shoot.
Alright, that is it for today. Hopefully, these pistol aiming tips has taught you the importance of sight alignment over trigger control. If you don’t believe it, go to a range and test it out yourself. I hope this has helped you out and until next time, keep paving your path to perfection.


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What was Braddock’s road and why was it so important?
The Braddock Road was a military road built in 1755 in what was then British America and is now the United States. It was the first improved road to cross the barrier of the successive ridgelines of the Appalachian Mountains. It was constructed by troops of Virginia militia and British regulars commanded by General Edward Braddock of the Coldstream Guards, part of an expedition to conquer the Ohio Country from the French at the beginning of the French and Indian War, the North American portion of the Seven Years’ War. George Washington was an aid-de-camp to General Braddock (one of his favorites) who accompanied the expedition. The expedition gave him his first field military experience along with other American military officers. A number of these men would profit from this experience during the Revolutionary War.
In 1755, Braddock was sent to remove the French from Fort Duquesne (Pittsburgh). Starting from Fort Cumberland, Braddock’s army cut a military trail through the wilderness, roughly following Nemacolin’s path, an improved, prehistoric Native American trail.
Braddock met defeat east of Fort Duquesne and was fatally wounded. He was buried in the middle of the road he built, and his soldiers marched over the grave, with the hope of concealing the grave’s location from the Indians. The grave was found years later by road workers and the grave was moved. The site is now marked by a marble monument erected in 1913.
The Forbes Expedition, a more successful British expedition mounted against Fort Duquesne in 1758, used a different route through the mountains west of Carlisle, Pennsylvania along what became known as Forbes’ Road.
In August 1908 and again during June and July 1909, John Kennedy Lacock, a Harvard professor originally from Amity, near Washington, Pennsylvania, was able to identify the path of Braddock’s march. He hired Ernest K. Weller to photograph the road. Lacock’s commissioned photographs survive in the form of postcards, which he published in 1910, and his written account was published in the Pennsylvania Magazine of History and Biography in 1914. It should be noted the road Lacock discovered was a road made by over 30 years of colonial settlers following Braddock’s trail.

domain: library


If you haven’t been spending your time watching straight-to-BET movies starring D-list celebrities, you probably haven’t heard Marques Houston’s name in a while. However, with a new deal to Musicworks Inc./Capitol Records, Houston is ready to begin where he left on the R&B charts with his new single Kickin and Screamin. Alongside his reliable producers Chris Stokes and Eric Crawford, the comeback single should be a banger right? When the production started, it sounded like a mix of LOL Smiley Face with a drum beat from Omarion’s I Get It In – not really what I was expecting. However, when Marques’ vocals came in, I became somewhat upset. Don’t get me wrong, the man can sing, but ending every bar in the first verse with “Motherf***a?” Who does that?! If this single is a preview of what Houston’s new album Mattress Music sounds like, I’ll personally be fine without it – what do you think, Booth readers?
Listen to More: Marques Houston
Written by JRTheWriter on 04/15/10
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Postcoital rupture that is vaginal an uncommon but well documented complication of hysterectomy. Evisceration of this intestine that is small genital bleeding and pelvic discomfort are typical presenting features. We report the case that is unusual of rupture presenting with generalised peritonitis without genital evisceration.
Postcoital rupture that is vaginal a unusual but well documented problem of hysterectomy. Evisceration for the tiny intestine is a very common presenting function and might be associated with genital bleeding and pain that is pelvic. These signs often happen during or right after sex and also the diagnosis is self obvious. We report the case that is unusual of rupture presenting with generalised peritonitis without genital evisceration 4 times after sex and 10 months after having a laparoscopic hysterectomy.
A 35-year-old woman presented into the accident and emergency division with a 4-day reputation for stomach discomfort. The pain was generalised, colicky and modern in general. It had been related to anorexia, vomiting and constipation for 48 hours. She admitted to being intimately active but denied any irregular discharge that is vaginal bleeding. At that time, neither ended up being she asked directly whether or not the start of discomfort coincided with intercourse nor did she volunteer these details. Her previous health background contained a laparoscopic hysterectomy ten months early in the day for dysfunctional uterine bleeding and pelvic discomfort, hypothyroidism and bowel syndrome that is irritable.
On assessment, the in-patient seemed unwell with significant stomach discomfort. Initial observations revealed a temperature of 37.4єC, a blood that is systolic of 121mmHg and a tachycardia of 103 beats each and every minute. Her stomach ended up being swollen with generalised peritonism and tenderness. Rectal and examinations that are vaginal maybe perhaps not done when you look at the crisis division. 继续阅读Postcoital rupture that is vaginal hysterectomy presenting as generalised peritonitis


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These 3 Colorado Train Rides Were Just Named Some Of The Best In America
All aboard! Do you have an affinity for trains and/or want to experience nostalgia for your childhood? The best way to do so is to – of course – come aboard one of Colorado’s scenic train rides. Not sure which to check out? Why not embark upon some of the best train excursions in Colorado – all of which have also been named among the best train rides in the country?
More to Explore
Best Train Rides in Colorado
Where can I go on scenic train rides in Colorado?
Life in Colorado is beyond beautiful, and we think there are few ways more amazing to really appreciate it than an amazing scenic train ride. Luckily for those who appreciate the rails, there are many options – all of which are worth a try! There’s the Royal Gorge Route Railroad, out of Canon City, which is one of the top-rated scenic train rides in Colorado. We also love the amazing Georgetown Loop Railroad, another very highly rated Colorado train excursion sure to thrill even the youngest (or pickiest) of riders. And, of course, we have to mention the Colorado Railroad Museum, in Golden – it offers steam rides on Saturdays!
What are some of the best train rides in Colorado?
Amazingly, the list does not stop with the railroads as mentioned above; that list is merely the beginning! Some other amazing train rides in Colorado include the Durango and Silverton Narrow Gauge Railroad, out of Durango, which takes guests on historic train rides through some of the most beautiful places in Colorado. In Manitou Springs, we recommend the Broadmoor Manitou and Pikes Peak Cog Railway, which offers amazingly scenic train rides in Colorado up to the top of Pikes Peak. This one is definitely a can’t-miss for locomotive enthusiasts and lovers of the natural wonders of Colorado alike.
Where are some of the most scenic places in Colorado?
Would it be cheating to say that all of Colorado encompasses the most scenic places in Colorado? Yes? Okay, fine. We do have some amazing favorites, no matter what kind of landscape you prefer. Lovers of mountains and forests will fall in love with Breckenridge, a breathtaking ski town so beautiful that it quite literally inspires postcards. If you’re a fan of open spaces, plains, and hills, check out Simla – it's a tiny, blink-and-you-miss-it town filled with rolling emerald hills and endless skies. Estes Park is stunningly beautiful, and just about every single state park in Colorado is worth a visit at some point. Colorado is beautiful, and you truly cannot go wrong with a visit to just about anywhere.

domain: geography


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Scaling up the system in a way that protects the interests of all concerned, including local communities, will take a little bit of time. It will take several months to reach full capacity. However, on 19 October, I set out our intention to welcome 1,000 Syrian refugees (adults and children) before Christmas. This is the ambition that the Home Office are working towards and we will report on it after Christmas.
We are not expecting the refugees arriving in the first months of the scheme to include unaccompanied children.

domain: sociology


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I’ve been thinking a lot recently about what my definition of experience design is. I think that this is a result of recent conversations where the question has been asked, and my alignment with the school of thought where experience design takes a more holistic approach, not just the traditional narrow definition.
For years, when you mentioned user experience, people automatically thought websites or applications. But experience design is such a wider scope. It is the design of all points of experience. That can manifest itself as the brand identity, the packaging, an environment… the design of the product itself. Aligning those touchpoints and considering how each one effects another and builds upon each other to create the experience as a whole — well, now we’re on to something.
Mapping out those points of interaction and designing for each is where experience design lives. When disciplines collaborate with the goal of creating great experiences, one big idea can expand into a whole ecosystem and engage customers at every touchpoint by delivering and building value. This is the new future of experience design, and something that excites me. It’s what gets me up in the morning and makes me want to keep striving to do better work.

domain: design


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August 11, 2011
Serial Killer T-Cells Destroy Leukemia Tumors
In a cancer treatment breakthrough, scientists for the first time have used gene therapy to successfully destroy tumors in patients with advanced chronic lymphocytic leukemia (CLL).
Researchers from the University of Pennsylvania's Abramson Cancer Center and Perelman School of Medicine have shown sustained remissions of up to a year among a small group of advanced CLL patients treated with genetically engineered versions of their own T cells.The procedure, which involves removing patients' cells and modifying them, then infusing the new cells back into the patient's body following chemotherapy, provides researchers with a new outlook in ways to treat other forms of cancers including those of the lung and ovaries.
The study findings, which were published today in the New England Journal of Medicine and Science Translational Medicine, are the first demonstration of the use of gene transfer therapy to create killer T cells aimed at cancerous tumors.
The treatment trial included three patients suffering from CLL, a disease that affects up to 4,000 people annually in the UK. Two of the participants in the Phase I trial have been in remission for up to one year. The third had a strong anti-tumor response, and his cancer remains in check. The researchers plan to treat four more CLL patients before moving into a larger Phase II trial.
Senior study author Professor Carl June said the treatment was so powerful that tumors were destroyed in under a month with few side effects.
"Within three weeks, the tumors had been blown away, in a way that was much more violent than we ever expected," said June, director of Translational Research and a professor of Pathology and Laboratory Medicine in the Abramson Cancer Center. "It worked much better than we thought it would."
The patients in the trial had few other treatment options. The only potential curative therapy would have involved a bone marrow transplant, a procedure which requires a lengthy hospitalization and carries a minimum 20 percent mortality risk -- and even then only offers a 50 percent chance of a cure.
"Most of what I do is treat patients with no other options, with a very, very risky therapy with the intent to cure them," said study co-author David Porter, MD, professor of Medicine and director of Blood and Marrow Transplantation. "This approach has the potential to do the same thing, but in a safer manner."
June thinks there were several "secret ingredients" that made the difference between the uninspiring results of past trials and the remarkable responses seen in the new trial.
After removing the patients' cells, the team reprogrammed them to attack tumor cells by genetically modifying them using a lentivirus vector. The vector encodes an antibody-like protein, called a chimeric antigen receptor (CAR), which is expressed on the surface of the T cells and designed to bind to a protein called CD19.
Once the T cells start expressing the CAR, they focus all of their killing activity on cells that express CD19, which includes CLL tumor cells and normal B cells. All of the other cells in the patient that do not express CD19 are ignored by the modified T cells, which limits side effects typically experienced during standard therapies.
The team engineered a signaling molecule into the part of the CAR that resides inside the cell. When it binds to CD19, initiating the cancer-cell death, it also tells the cell to produce cytokines that trigger other T cells to multiply -- building a bigger and bigger army until all the target cells in the tumor are destroyed.
The researchers say their success in the new trial is "unprecedented."
"We saw at least a 1000-fold increase in the number of modified T cells," they wrote, adding that it occurred in each of the patients in the trial. "Drugs don't do that," they added.
"This is very encouraging and it's definitely a step in the right direction, although a lot more work is needed to see if it can benefit more patients as this is a small sample," Dr David Grant of the charity Leukemia and Lymphoma Research told the Daily Mail.
"But gene transfer therapy to strengthen immune cells is a much more attractive option than toxic anti-cancer drugs and it is an approach we are also working on in Britain, so this is promising in bringing us closer to helping more patients," he added.
Two British trials of this gene therapy are opening next year in London, one for acute myeloid leukemia and the other for acute lymphoblastic leukemia.
Dr. Walter Urba of the Providence Cancer Center in Portland Oregon cautioned that continued presence of activated T cells and memory cells might be more of a problem in other types of cancer where toxic effects on normal tissue could be severe.
"One of the big questions is ... will those persistent T-cells continue to work and prevent that tumor from coming back," Urba, who was not involved in the study, told Reuters.
The research team pioneered the use of the HIV-derived vector in a clinical trial in 2003 in which they treated HIV patients with an anti-sense version of the virus. That trial demonstrated the safety of the lentiviral vector used in the present work.
The team plans to further test the same CD19 CAR in patients with other types of CD19-positive tumors, including non-Hodgkin's lymphoma and acute lymphocytic leukemia. They also plan to study the approach in pediatric leukemia patients who have failed standard therapy. Additionally, the team has engineered a CAR vector that binds to mesothelin, a protein expressed on the surface of mesothelioma cancer cells, as well as on ovarian and pancreatic cancer cells.
The gene therapy trial, which was expensive, was funded entirely from the academic community.
On the Net:
- University of Pennsylvania School of Medicine
- Abramson Cancer Center
- Perelman School of Medicine
- New England Journal of Medicine
- Science Translational Medicine


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Big Tall Small, a puzzle platform game, tasks players to do everything they can to help three characters of different sizes and colors reach portal-style exits in each level.
Players must use a standard QWERTY keyboard to move around in the game. For side-to-side and up-and-down movement, they can use arrow keys or tap the "W," "A," "S" and "D" keys. The up arrow key can make a character jump. To switch between characters, players can use the down arrow, space bar or enter key. A pointing arrow appears above the head of the character until the player selects the one they want to play. To reset the game, they merely need to tap the "R" key. Lastly, to go back, they tap the "B" or "Esc" keys.
On the main screen, the player turns off the sound and music by using the down arrow key to move the blue cursor in front of one of these options and then presses the left arrow key repeatedly to decrease the number. To increase the volume, they press the right arrow key repeatedly. To start the game, they use the up arrow key to move the blue cursor next to "Start" and then tap "Enter."
To pass through the levels, they must move each character, Big, Tall and Small, to a swirling purple icon that represents a portal or exit that leads to another area of the game by tackling the obstacles and puzzles in the current level. Each character has special abilities and traits that make it easier for them to handle specific obstacles to help the characters reach the next portal. For example, a player can use the red character, Big, to push crates out of the way.
With Big, Tall Small, players can enjoy hours of arcade-style platformer fun!

domain: game


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GREENSBORO, N.C. - The Pfeiffer University women's cross country team competed Saturday afternoon at the Greensboro Cross Country Invitational at Hagan Stone Park. Pfeiffer finished 2nd to Concord University out of West Virginia in an eight team field, two points ahead of third place St. Augustine's College.
For the day, the Lady Falcons posted four personal record performances, including freshman Lindsey Phillips, who finished first for Pfeiffer was 3rd overall with a time of 19:34. Kaitlyn Mullis second on the team in 11th overall with a personal best 21:09 followed by Magen Abernathy in 13th with a 21:25. "I told Lindsey she needed to start strong - and after the first 400 meters she was leading the race," recounts head coach Scott Nolt.
Freshman Yasmin Ingram from Parkland High School finished fourth on the squad with a 22:38, nearly three minutes faster than her best time from high school. "I think Yasmin surprised herself today with her finish. She is a very talented runner who really stepped up for us today," stated coach Nolt. Pfeiffer's fifth place runner was Chelsea Tysinger, in her first race of the season after a knee injury sidelined her for the first month. Tysinger finished 34th with a time of 24:02. April Hinson finished sixth for Pfeiffer with a personal best time of 24:30.
Post-race, coach Nolt was very pleased. "The girls continued to step up in the face of adversity. I think we have had two girls who haven't been sick or injured in the last two weeks." Pfeiffer had four runners who didn't compete due to injury.
Pfeiffer runs again this Friday October 2nd at McAlpine Creek Park in Charlotte, NC where they will get to compete on the course that will host the Conference Carolinas meet later in October.
Click HERE for Team Results
Click HERE for Individual Results


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Engineers Dice x10
- Out of stock
Engineer's Dice x10 Product Description
Proudly display your loyalties to the inventive Engineer’s Guild with our stunning marbled dice, the sight of the faction emblem heralding another step on the road to victory.
This product contains:
• 10X Engineer’s Guild Dice

domain: hobby


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Redondo Beach Crab House
The actual fact of make any difference is the fact that merrily having a top quality seaside house layout isn't really approximately enough. You have to get further steps to grasp in which you are developing, and insure that it's stable more than enough to support your strategies. Character isn't transforming for and will have to understand that you will discover only destined to be an ever-increasing amount of natural disasters, and you simply are wise to just take into consideration every one of the pressure of character can have an effect on your seashore. It really is not in regards to the aesthetics by itself. Not by a protracted shot The Fish House Long Beach.
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Read more: Open Plan Beach House Designs


Archive for February 6th, 2015
‘We have a lot of work to do’ / America
Posted by Voice of the Faithful in Catholic Bishops, church reform, Future of the Church, Synod of Bishops, Women in Catholic Church on February 6, 2015
Cardinal Marx on Pope Francis, the synod and women in the church
Cardinal Reinhard Marx, archbishop of the Diocese of Munich and Freising, is head of the German bishops’ conference, a member of the Council of Cardinals that advises Pope Francis on church governance, coordinator of the Vatican’s Council for the Economy and author of Das Kapital: A Plea for Man (2008). Cardinal Marx delivered the annual Roger W. Heyns Lecture on Jan. 15 at Stanford University in California. This interview, which has been edited for clarity and approved by the cardinal, took place on Jan. 18 in Memorial Church at Stanford University.”
By Luke Hansen, S.J., America — Click here to read the rest of this interview.
It’s official: Pope Francis will address the U.S. Congress / Cruxnow.com
Posted by Voice of the Faithful in Pope Francis, Voice of the Faithful on February 6, 2015
In what will be a first for a pope or religious head of state, Pope Francis will address a joint session of the US Congress Sept. 24, Speaker of the House John Boehner confirmed Thursday.
“But whether Republicans and Democrats will like what they hear is an open question.”
By Michael O’Loughlin, Cruxnow.com — Click here to read the rest of this story.


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Cucumber, White Wonder (100% Heirloom/Non-Hybrid/Non-GMO)
- Rare white heirloom cucumber variety.
- Produces beautiful white cucumbers about 6" long x 2" thick
- Heat tolerant
- Excellent variety for any sized backyard garden, raised beds, or containers
- Amazing flavor and very tender
Day to Maturity | 55-60 days
Cucumber Seeds | Grow cucumbers where a long, warm growing season, minimum 65 days, can be assured. Plant seeds where there is ample space and vines can sprawl, the simplest way is to plant cucumbers in hills.
Click here for complete Cucumber grow guide
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domain: agronomy


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Its been few days now and still got no chance to have the armory mystery box i played and played but no drops. My teammate he just played yesterday and he got his mystery box on his first dungeon. Can you check if my algo because i found a nft and it was a weapon… im thinking that the algo recognized it as my mystery box… thank you!
Its apart of the random loot pool from my understanding. From what I know there is still plenty out there just keep grinding with a full party of 6 for the best chances of NFTs and a chance at the mystery box. Do keep in mind the silver mystery box is not guaranteed to be dropped for everyone so keep at it and good luck friend !!!
mystery boxes are not guaranteed


This week, the Inter-Agency Task Force on Israeli Arab Issues (IATF) was named among the Top 50 Jewish innovators in Slingshot’s 2010-2011 guidebook. The Task Force, proudly co-chaired by JDC’s CEO Steve Schwager and housed here at JDC headquarters in NYC, is a diverse coalition of over 90 Jewish organizations dedicated to educating the Jewish community about issues facing Israeli Arabs—20% of Israel’s population—in support of a secure, just, Jewish, and democratic state.
As part of JDC’s work in Washington, Board members and staff traveled to our nation’s capital for meetings, culminating in a session with White House officials. Susan Sher (First Lady Michelle Obama’s Chief of Staff) and Danielle Borrin (Associate Director of Public Engagement), who serve as President Obama’s liaisons to the Jewish community, engaged with JDC representatives to learn about our work.
This past Sunday, October 10, the city of Timisoara opened the doors of a new Jewish Community Center (JCC)—the fourth in Romania following others in Bucharest, Oradea, and Iasi. More than 300 people attended the opening celebration, which included a concert followed by an “after-party” for local Jewish youth.
Celebrating Jewish Culture in the Streets of Ukraine
It’s not every day you see a sign promoting Jewish activities on a busy street corner in Ukraine. But this week in Kharkov, an estimated 10,000 people are experiencing the sights and sounds of Judaism in the city’s Days of Jewish Culture celebration—a project run by the local JDC-supported Beith Dan Jewish Community Center. The festival, running October 3-10, highlights the richness and variety of Jewish culture through music and dance performances, workshops, concerts, art exhibitions, and other engaging activities for all ages.
JDC & Susan G. Komen for the Cure Promote Breast Cancer Awareness in Bosnia
Today, more than 3,000 Bosnians will hit the streets of Sarajevo in honor of breast cancer awareness month. JDC and Susan G. Komen for the Cure are hosting their third annual Race for the Cure. The event brings together people of all backgrounds including those from the Bosnian, Muslim, Croatian, Jewish, and Serbian communities. The funds raised at the 2010 Race will be used to distribute immediate post-surgery medical kits to women and provide free mammogram checkups for those who are uninsured.
As we reported last week, two Torahs handed over to JDC by the New York District Attorney were to make their way to new homes in Sofia, Bulgaria and Belgrade, Serbia. Timing is everything and government representatives in New York for the UN General Assembly enthusiastically offered to personally escort the Torahs back to Europe.
NY District Attorney’s Office Hands Over Rescued Torahs to JDC for Overseas Communities
In time for Simchat Torah next week, Jewish communities in Sofia, Bulgaria and Belgrade, Serbia will each get a very special delivery about which to rejoice: a torah. The two Torahs, which were stolen by a Brooklyn man and ended up in the hands of the New York District Attorney’s office, are being donated by JDC to these Eastern European communities. In Sofia, the Torah will help replace scrolls stolen from the synagogue 10 years ago. In Belgrade, it will be the first kosher Torah used since the breakup of Yugoslavia when Jewish community assets were divided.
As Yom Kippur descends upon us, Jewish communities around the world prepare for the traditional holiday customs: pre-sundown meal, synagogue services, fasting, breaking the fast…and of course, intense personal reflection. However, Day of Atonement rituals were not always so easily understood or embraced.
We at JDC know well that Rosh Hashanah traditions can take on their own unique flair from one country to another. A recent article in Slate shares that for the 35,000 Hasidim (ultra Orthodox Jews) that embarked on the annual pilgrimage to Uman, Ukraine (125 miles south of Kiev where the Breslov Hasidic sect’s founder, Rabbi Nachman, is buried), it was an inclusive and nearly 200-year-old “pray, eat, love” fest.
During this week between Rosh Hashanah and Yom Kippur, Jewish communities around the world are taking the time to reflect, recount, and reenergize for the year ahead. We here at JDC are no exception. Steve Schwager, our CEO, shares his own thoughts about the legacy of JDC, what we’re doing to help Jews in need, and who is still in need of our support. Excerpts below.
Trying to imagine that you are transforming someone’s life in another country is no match for actually meeting the person whose life you’re changing. That’s why we were heartened that participants on the Jewish Federations of North America’s recent mission to Haiti created a blog to share the impact that their generous donations—and that of tens of thousands of others—is having on the Haitian people. Echoing that sentiment, Gideon Hersher, JDC’s representative in Haiti, reflects in the Jewish Journal of Greater Los Angeles on the progress being made on this devastated island as Rosh Hashanah approaches.
For Israel’s 700,000 adults with disabilities, this year will be brighter because of JDC’s special-needs partnership, Israel Unlimited, which was found together with the Ruderman Family Foundation and the Government of Israel. The goal of the collaborative effort: to successfully integrate these Israelis into society and live productive and healthy lives. The program is crucial as people with disabilities comprise 20% of Israel’s population.
Szarvas is More than Summer Camp for Albanian Jewish Teen
Not ready for summer to end? Neither is Besart, a 15-year-old from Albania whose exhilarating experience at the Ronald S. Lauder Foundation/JDC International Summer Camp at Szarvas, Hungary, has helped cement his Jewish identity. And that’s no small feat, considering that Besart is one of just 30-some Jews currently living in Albania. Prior to attending Szarvas, he didn’t have a single Jewish friend; now he has a whole community.
On August 31, 1914—96 years ago today—two men, Jacob Schiff and Henry Morgenthau, exchanged an urgent cablegram in an effort to help Palestinian Jews who faced an existential crisis due to resources from Europe being cut off with the outbreak of World War I. Little did they know (or probably even imagine) that this single action would give birth to the world’s leading Jewish humanitarian assistance organization that today comprises hundreds of staff working in more than 70 countries, and ensuring that just shy of $1 million per day goes to helping needy Jews everywhere.
Earlier this month, we shared the launch of GuideStar Israel, a comprehensive database and resource on the 30,000 registered charities in Israel realized by JDC, the Israeli Ministry of Justice, and Yad Hanadiv (The Rothschild Foundation). NP Tech (established by JDC and Yad Hanadiv), the operating organization behind GuideStar Israel, helps these non-profit organizations further their missions by making information and communication technology more accessible to them. That means helping NGOs use comms and info tech tools to fundraise, mobilize volunteers, focus the public debate on specific issues, and more.
As the floods in Pakistan show no signs of dissipating, JDC is executing emergency relief assistance in collaboration with partners on the ground. We are working with Heart to Heart International, the Afya Foundation (both of whom serve as our partners in Haiti), and the International Blue Crescent (with whom we collaborated after the 2005 and 2008 earthquakes in Pakistan). Interested in supporting our efforts? Make a donation to JDC’s Pakistan flood relief fund.
Leyla Sandler, a social worker based in Washington D.C. and a member of JDC’s Next Gen steering committee, took her expertise to the field, volunteering alongside JDC-supported aid efforts in Haiti. Read her account of the trials and triumphs at the Bel Air clinic in Port-au-Prince.
Last week, JDC’s Next Gen group held an event: Inside Jewish Ukraine, in partnership with Combined Jewish Philanthropies (Boston’s Jewish Federation). JDC, through the experiences of two speakers—one JSC fellow and one RIG fellow—who recently lived and worked in Ukraine, shared the realities of modern-day Jewish life in the former Soviet Union. While the purpose of the evening was to discuss JDC’s current efforts to bolster Jewish cultural life in the region, our history working in the FSU through both World Wars and then post-communism seemed to resonate with attendees as well.
JDC Continues Legacy of Providing Aid to Pakistani Disaster Victims
Pakistani flood victims who will be helped by JDC will join the ranks of tens of thousands of their fellow citizens whom JDC has reached with humanitarian assistance following natural disasters in Pakistan within the past five years alone.
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Former porn star Jenna Jameson opens up about dealing with 'loose skin' after losing sixty pounds. Jenna Jameson flaunted her trim figure in a bikini after shedding more than 80 pounds with the keto diet. It is now.
Published: June 21, Nang Mwe San, 29, has been banned from practising medicine in Burma after she continued to share sexy snaps of herself in bikinis. Nang Mwe San, 29, has been now banned from practising medicine after being warned numerous times about posting sexy snapshots of herself on Facebook.
My great wish for all the women of the world is that we carry ourselves with confidence and self love when we're at the pool or the beach. Whatever you've got, wear it like the goddess that you are. But if you're concerned about avoiding humiliation while frolicking half-naked in public, there are a few swimsuit wardrobe malfunctions you should prepare yourself for.
A Myanmar Medical Council has stripped a doctor of her licence to practice after she refused to remove photos of herself in a two-piece swimsuit. In September ofa mass exodus of Muslim Rohingya left Myanmar, heir religious beliefs mark them as outsiders and targets of discrimination and they are considered one of the most persecuted minorities in the world. Dr Mwe San began sharing photos of herself, wearing two-piece swimsuits on her social media accounts.
For all the pitches urging us to lose weight for a bikini-perfect body, rarely do we hear about the sagging skin that can remain after we slim down. This woman is the perfect example of what women look like after major weight loss. I applaud her for being brave!!
Sophie Gray. Instagrammer Sophie Gray was once known for posting bikini photos of herself and workout videos galore on her account. But recently, Gray decided to rework her account to promote a healthier body image instead.
Nang Mwe San, 29, has been now banned from practising medicine after being warned numerous times about posting sexy snapshots of herself on Facebook. And as a result, San — who became a doctor when she was 22 — packed in her stethoscope and pursued her lifelong dream of being a model. Nang Mwe San, 29, has been banned from practising medicine in Burma after she continued to share sexy snaps of herself in bikinis.
June 19, pm Updated June 19, pm. After several years of treating patients, Nang Mwe San began to share photos of her in a two-piece to social media and began participating in professional photo shoots. And they judge women on what we wear.
A year-old body positivity advocate has spoken out about why she chooses to flaunt her body and speak out about self-love, after she was mercilessly trolled and taunted for her body while in Malta for the Lost and Found festival. Florence Grace, from Buckinghamshire, an influencer, writer and blogger, went to the festival last week with her boyfriend. Florence told Metro.


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A crazy dance floor at a Colorado Wedding.
Sikh man at the Gurdwara Shri Bangla Sahib temple in Delhi. India
Charlie Buhl bouldering with mom in Boulder, CO
Woman preparing beetle leaves in her stall.
A dog buried in the sand.
An ultra modern home by a mountain stream in the Colorado mountains. Photograph by architectural photographer Braden Gunem Durango, Colorado.
Frederic C. Hamilton Building of the Denver Art Museum. Denver, Colorado, United States of America


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March Insanity: Enjoy 5 FREE balls with each iFetch Original purchase whilst stocks last. Anyone who has a canine as a part of their family will know that there are a few things our canine love more than a great, previous tennis ball. With regards to tennis balls, the rule for our furry connoisseurs appears to be the grubbier, the older and the smellier the higher! It’s no secret that canine simply love to chew and chase balls, and there’s nothing they take pleasure in more than taking part in with their house owners.
This Bazook – 9 Tennis Ball Launcher Gun is the newly improved 2017 mannequin and can be used with regular tennis balls. To fireside simply seize the handle ifetch and pull back the rear rod. I hope this guide helps you and your dog get as a lot out of your computerized ball launcher as Carl and I do.
iFetch takes the guilt out of leaving your fur babies alone when you head out to work or obtain life’s vital duties away from home. Not solely does this progressive little device get your pooch up and out, it workout routines their body AND thoughts.
Locating Speedy Methods Of I fetch
Useful: The launcher has a nice deal with built into the design, however the fact that it requires six D-cell batteries makes it a bit heavy. This toy will stimulate your pet to play even if you find yourself not obtainable ifetch to him. With the handbook launchers be aware of supplies and design. Flexible does not necessarily equal safer or further. You additionally want to contemplate throw sorts.
Some automatic dog ball launchers, just like the iFetch Interactive Ball Launcher , are made particularly for smaller dogs. The ball chute is located on the back while the launching mechanism points forwards. The ball is thrown nearly immediately after the ball is dropped into the chute to forestall injury. It is powered by an internal rechargeable battery for versatility.
Determining the battery life of a unit and when you need to use are thus important concerns when determining one of the best ball launcher for dogs you own. Indoor and Outdoor Play. We already mentioned the gap changes are great for with the ability to play outdoor or indoors, but most launchers additionally include elective battery energy so you should not have to run extension cords.
Those who purchased and reviewed this dog ball launcher appreciated that the launch energy could possibly be adjusted, which suggests this machine can be utilized each indoors and outdoors. Most homeowners found it launched persistently and reliably, and thought the ball size was excellent for small breeds like chihuahuas.
The Facts On Essential Factors In I fetch
The Chuckit! handbook ball thrower is an all-time classic for prime-power, fetch-loving dogs. The Chuckit launcher can throw a ball much further than an automated ball launcher, and is especially great when utilized in wide open spaces with tons of room to run.
Some launchers resembling Hyper-four Tennis Ball Launcher may even shoot balls over 220 ft! I really recommend getting no less than considered one of this manual launcher to play along with your dog if you have free time afterward. It’s an effective way to exercise and develop a bond along with your canine. Keep in mind, a manual launcher is just finest suited to play outdoor, don’t do that inside your house. This handbook launcher can be best suited if you wish to play a floating water fetch recreation with your dog.
This iDogmate ball launcher will give your canine hours of play because of a profitable design and some really sensible features. Let’s talk about distance first. There are 4 totally different distant settings that you could switch between, with the closest 10 feet and the farthest as much as 50 toes away. You too can set it for 20 feet and 40 toes. 50 toes is without doubt one of the farthest distances for automated ball launchers available on the market. What is de facto helpful is that incorporates a random feature in order that your dog never goes how far the field going to go. This makes the much more fun, and retains them from getting bored. This automated fetch machine is nearly like a human being is throwing the ball.
Dogs within the state of Illinois are required by law to be vaccinated for Rabies. Cats vaccination requirement varies depending on what county you live in. Champaign County requires cats to be vaccinated. Douglas County doesn’t require cats to be vaccinated. We highly advocate having cats vaccinated for Rabies. Cats who go outdoors are exposed to Rabies, similar to canine. Canines and cats are given their first Rabies vaccine when they’re four months old. The vaccine is boostered every one to three years, depending on the type of vaccine given. It is necessary on your pet to have an examination previous to receiving any vaccination. If your pet is ailing, the vaccine can make them sicker. Giving a vaccine to an unwell pet can even trigger the vaccine to not be efficient at stopping the disease.


Globe specifically chose Snowflake to help it leverage its trove of data and accelerate its internal transformation journey in the process. The Snowflake-Globe partnership aims to democratise data and enable data-driven decision-making.
“We want to make decision-making powered by data possible to as many job functions in the least possible time with the least dependency from others,” said Dan Noel Natindim, Vice President, Enterprise Data Office, at Globe. “While we’re happy with 68% of our ad-hoc reports being fulfilled via self-service, it is not enough. Users and executives always want to get deeper into data and have more questions.”


Developer Portrait: Erik Lohr
Erik is a senior audio engineer developing new ways of storytelling through emerging XR immersive formats. Collaborating with the Sennheiser team opens up exciting opportunities to explore deeper ways of immersing audiences with AR-based audio applications. The forthcoming app allows users to place virtual remix objects within their environment to be played in real time, creating their own unique remixes. Harnessing the Leia AU framework, very realistic binaural rendering is possible. The user can move freely around the ‘stage’ and easily manipulate objects in the real world environment using their iPhone, experiencing object-based spatial audio. Featuring original music from electronic duo Ricoshëi.


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Autoimmune diseases, in which the immune system attacks the body, are fairly common. Thyroid diseases, type 1 diabetes, rheumatoid arthritis, psoriasis and inflammatory bowel disease are some examples. Autoimmune diseases are associated with increased inflammation in the tissue, which in some cases is linked to an increased propensity to develop clots in the veins.
“The most dangerous complication of a blood clot is a blood clot on the lung”, says Associate Professor Bengt Zöller, who is the principal investigator for the study, which was carried out at the Centre for Primary Health Care Research in Malmö, Sweden.
The study involved 535 000 patients who had been admitted to hospital for 33 different autoimmune diseases. The risk of a blood clot on the lung was compared with the risk for individuals who had not been admitted to hospital for an autoimmune disease. The risk was adjusted to account for other diseases, age and socioeconomic factors. The results show that 31 of the 33 autoimmune diseases studied were associated with an increased risk of a blood clot on the lung.
“The risk was particularly high in the first year – around six times higher on average in all the groups with autoimmune diseases compared with the control group. For some of the diseases, the risk was even higher in the first year”, says Bengt Zöller.
The diseases that stand out are idiopathic thrombocytopenic purpura (lack of platelets caused by an immune response), systemic lupus erythematosus (SLE), polymyositis (muscle inflammation), dermatomyositis (skin and muscle inflammation) and polyarteritis nodosa (inflammation in medium-sized arteries), which all had at least a tenfold risk increase. Rheumatoid arthritis, a relatively common disease, was associated with a sevenfold increase in the risk of a blood clot on the lung. Type 1 diabetes entailed a sixfold increase in the risk of a blood clot on the lung in the first year following hospital treatment.
“The risk of a blood clot fell with time. It was still around 50 per cent higher after 1–5 years, yet there remained an increased risk for up to ten years after the first admission to hospital for many autoimmune conditions”, stresses Bengt Zöller.
The research suggests that it is possible that patients who have been admitted to hospital for autoimmune diseases require preventive treatment for blood clots in the same way as following major surgery.
“However, further controlled studies are needed to determine the effect of preventive treatment”, says Bengt Zöller.Publication:
Bengt Zöller, Centre for Primary Health Care Research, Lund University and Region Skåne, Sweden, +46 40 391954, +46 706 691476, firstname.lastname@example.org
Megan Grindlay | idw
The personality factor: How to foster the sharing of research data
06.09.2017 | ZBW – Leibniz-Informationszentrum Wirtschaft
Europe’s Demographic Future. Where the Regions Are Heading after a Decade of Crises
10.08.2017 | Berlin-Institut für Bevölkerung und Entwicklung
Our brains house extremely complex neuronal circuits, whose detailed structures are still largely unknown. This is especially true for the so-called cerebral cortex of mammals, where among other things vision, thoughts or spatial orientation are being computed. Here the rules by which nerve cells are connected to each other are only partly understood. A team of scientists around Moritz Helmstaedter at the Frankfiurt Max Planck Institute for Brain Research and Helene Schmidt (Humboldt University in Berlin) have now discovered a surprisingly precise nerve cell connectivity pattern in the part of the cerebral cortex that is responsible for orienting the individual animal or human in space.
The researchers report online in Nature (Schmidt et al., 2017. Axonal synapse sorting in medial entorhinal cortex, DOI: 10.1038/nature24005) that synapses in...
Whispering gallery mode (WGM) resonators are used to make tiny micro-lasers, sensors, switches, routers and other devices. These tiny structures rely on a...
Using ultrafast flashes of laser and x-ray radiation, scientists at the Max Planck Institute of Quantum Optics (Garching, Germany) took snapshots of the briefest electron motion inside a solid material to date. The electron motion lasted only 750 billionths of the billionth of a second before it fainted, setting a new record of human capability to capture ultrafast processes inside solids!
When x-rays shine onto solid materials or large molecules, an electron is pushed away from its original place near the nucleus of the atom, leaving a hole...
For the first time, physicists have successfully imaged spiral magnetic ordering in a multiferroic material. These materials are considered highly promising candidates for future data storage media. The researchers were able to prove their findings using unique quantum sensors that were developed at Basel University and that can analyze electromagnetic fields on the nanometer scale. The results – obtained by scientists from the University of Basel’s Department of Physics, the Swiss Nanoscience Institute, the University of Montpellier and several laboratories from University Paris-Saclay – were recently published in the journal Nature.
Multiferroics are materials that simultaneously react to electric and magnetic fields. These two properties are rarely found together, and their combined...
MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems Holding GmbH about commercial use of a multi-well tissue plate for automated and reliable tissue engineering & drug testing.
MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems...
19.09.2017 | Event News
12.09.2017 | Event News
06.09.2017 | Event News
21.09.2017 | Physics and Astronomy
21.09.2017 | Life Sciences
21.09.2017 | Health and Medicine

domain: biology


The brake lights are a separate circuit from the other lights. Check the fuses and bulbs. If fuses and bulbs are okay I would suspect the brake light switch is at fault.
Check the bulbs - they are doubloe filamented with the smaller being for brake/turn signals Check the fuses
Try replacing the hazard flasher. If that does not work, double-check to see that you have the proper bulbs and fuses installed for the brake lamp circuit.
I had this same problem. If the bulbs and the fuses are good its most likely the brake switch. Its a plunger like switch on the brake pedal. Its usually the only thing on the brake pedal. Its pretty easy and cheap to change. I would start there.
The brake lights are a separate circuit from the tail lights. If the bulbs and fuse checks okay, I would suspect the brake light switch is at fault.
If the fuses and bulbs are okay I would blame the signal switch assembly. They call it a multi-function switch these days.
Next step would be to check the fuses
If all the bulbs are good then it may be a blown fuse or a defective or mis-adjusted brake light switch.
If you are referring to the brake lights it is probably a bad brake light switch. Your vehicle may also have daytime running lights which would be on without the parking lights.
The bulbs are burnt out.
Console lights and brake lighting are on different circuits (Fused seperately). Check the following: bulbs, bases, corroded connections, poor ground, blown fuses, faulty light switch.
ya its called go to a mechanic you idiot
First, check all fuses. Then see if you are getting power to the bulbs. Then the next possibility would be the turn signal switch.
Check your fuses. Sometimes it is just that simple.
check the fuses
The brake lights and tail lights are separate wiring systems. Even some of the bulbs may have two separate bulbs in the same glass housing. If the bulbs are in fact working, then the next step would be to test the brake switch under the dash. When you depress the brake pedal the switch is pushed creating a connection to turn on the brake lights.
Are you blowing fuses or are the bulbs blowing? Blowing fuses would be a sign of any wires or metal contacts in your brake circuit grounding out or shorting on themselves. You'll have to check all of the wiring in your brake light/switch circuit to be sure.
Check your fuses. See owner's manual for location and assignment of fuses.
Brake bulbs. You might need to replace them. It just happened to mine and it was tricky to do it. To take the brake lights you need to pull them from the sides, there is a small piece that would come out easily and then you can just take the screws out.
Check the bulbs, if they are okay it is prob the brake light switch located under the dash so the brake pedal arm contacts it
i would heck that you have the correct double element bulbs in your tail light assembly
Check socket for corrosion-and make sure it is grounded
Check fuses or headlight switch
I am having the same trouble. My brake lights work with the light switch for nighttime driving, but only far right brake light works when i pres brake pedal. Reverse lights dont work at all. Turn signals and hazard light work.


Lexus has some big changes for the RX crossover and according to two reports, the 2023 RX will be offered with three hybrid powertrains.
Japan’s Creative311 and Magazine X are reporting that the next-generation 2023 Lexus RX will offer several hybrid powertrains, including a plug-in hybrid. At the top of the lineup the report claims that there will be the RX 500h, which will be a plug-in hybrid that will mate a turbocharged 2.4-liter four-cylinder to an electric motor. In the middle of the lineup, there’s the RX 450h+ which will reportedly be powered by a 2.5-liter four-cylinder and an electric motor. The base hybrid will be the RX 350h, which is powered by the same hybrid powertrain as the new NX 350h.
The non-hybrid RX is also slated to get a big change, with the current 3.5-liter V6 being dropped and its replacement being a turbocharged a 2.4-liter four-cylinder.
Lexus has not made any announcements about the 2023 RX, so we’ll have to wait and see if this report is accurate. It’s expected that the next-generation RX will be revealed later this year.


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Online bingo sites provide an array of payment methods, and it’s up to you which one of the options you choose. In this article, we take a look at the online bingo companies that offer EcoPayz as a payment.
Keep reading to learn all about EcoPayz bingo sites we recommend.
Table of Content
- 1 Best EcoPayz Bingo Sites
- 2 Opening Your Ecopayz Account
- 3 How to Use Ecopayz for Bingo?
- 4 Why is Ecopayz Popular?
- 5 Advantages of EcoPayz for Bingo
- 6 Disadvantages of EcoPayz for Bingo
- 7 Other Bingo Payment Options
- 8 Playing Online Bingo with Ecopayz
Best EcoPayz Bingo Sites
Check below to see our recommended list of the best EcoPayz bingo sites online.
Opening Your Ecopayz Account
It is a secure digital wallet that can be used by all players. It is simple to sign-up, and there are plenty of advantages. Many e-wallets are being selected over the likes of Visa and bank accounts, as it lessens the risk of fraud or other issues.
An e-wallet such as EcoPayz, formerly known as Eco Card, is one of the most secure deposit methods for the latest bingo brands.
Read on to find out what sites accept this type of transaction and why we believe it’s gaining popularity.
Opening this digital wallet is similar to opening a bank account. It doesn’t take as long, but you will be required to verify your identity. Doing this enables you to enjoy all of the bingo welcome promotions.
Here’s what’s required to open an EcoPayz account:
- Where You Live
- Your Name
- Bank Account, Bank Transfer or Credit Card
- Further ID & Proof of Identity
- E-mail Address
Visit their site and click onto the sign-up button. From there, you will be talked through the process. It is easy to register, and it will not take long.
If you have any issues, then you can get help from their online support.
How to Use Ecopayz for Bingo?
Bingo is a huge online market, and for that reason, there are various ways to pay. EcoPayz is one of many bingo payment types, but there are lots of reasons to opt for this. If you wish to go with this choice, you will want to know how to use EcoPayz for bingo.
Firstly, you will need to sign-up to EcoPayz. We have discussed that above. Once you have completed your registration, it is super-easy to deposit.
Simply, select the amount and then choose EcoPayz as your deposit option. From there it’s easy, follow the instruction, it takes seconds.
Why is Ecopayz Popular?
There are many reasons for EcoPayz’s popularity. Lots of e-wallets are now being used by those that flutter on betting sites. That is due to how secure they are and how easy they are to use.
Below are some of the reasons to use EcoPayz.
E-wallets are generally more secure than using your visa or bank card. If there were any interceptions or fraudulent behaviour, then the scammer would have access to your bank and identity. At least with this form of payment, you get the chance to separate the funds.
It is also regulated by FCA and has online encryption. The high-level security and dedication to keep your account safe will give you peace of mind.
You are probably wondering how the payment method can affect your promotions and welcome bonus amount. The likes of Skrill and Neteller are not always allowed to utilise the sign-up promotions, and this is due to the anonymity of those accounts.
Subsequently, customers have been taking advantage of the promotions again and again. This includes free bingo and many other exciting offers.
With EcoPayz, all betting sites allow you to act on the welcome promotions without hassle. Be sure to check the max bonus amount and wagering requirements for any offers you use.
Access & Ease of Use
It’s accessible in numerous ways. Not only is this method available on almost all of the popular betting sites, but you can also use it in over 160 countries. They have more than 45 currencies available.
It is simple to use and is widely used. It is more than a betting site payment. This method has been gaining traction in various industries for a long time.
Advantages of EcoPayz for Bingo
- Quick depositing process
- Easy way to separate your gambling funds from other money
- Low risk as you don’t have to share any bank details with bingo sites
- Requires two-step verification for security
Disadvantages of EcoPayz for Bingo
- Not accepted at all bingo sites
- There can sometimes be small fees to use this method.
Other Bingo Payment Options
Check out more payment options for bingo below.
- Skrill bingo sites
- Boku online bingo
- Debit cards
- PayPal bingo
- Paysafecard bingo deposits
- Neteller bingo payment
- Entropay bingo
Playing Online Bingo with Ecopayz
Playing online bingo with EcoPayz is a good choice, stay secure and enjoy easy to use features. It is a fantastic e-wallet that is easily accessible. You can make your first deposit with ease and continue using this method as you play.
Like most wallets of this kind, there are some fees to consider. We have listed it below.
- Pocketchange – Free
- Credit/debit card – 2.9%
- Fast Bank Transfer – 2%
- Instant Banking – €1.60
- Paysafecard – 7%
Opening an account with them is free and simple, it’s well worth signing up and using this account for all of your betting needs. Whether that’s for bingo or other online gaming.
It is secure, and we recommend using this type of deposit option over your bank card. There are other secure e-wallet options too, check them out on our site.
We have listed all of the best bingo websites that use EcoPayz, sign-up today and you can play all of the very best bingo rooms on the web.

domain: finance


Scientists from Oxford University, London Zoo and the Smithsonian Institution have found more than 40 previously unidentified species in Papua New Guinea ! In a rainforest currently being destroyed at a rate of 3.5% each year, this volcanic crater is a lost world is populated by fanged frogs, grunting fish and tiny bear-like creatures.
“A team of scientists from Britain, the United States and Papua New Guinea found more than 40 previously unidentified species when they climbed into the kilometer-deep crater of Mount Bosavi and explored a pristine jungle habitat teeming with life that has evolved in isolation since the volcano last erupted 200,000 years ago. In a remarkably rich haul from just five weeks of exploration, the biologists discovered 16 frogs which have never before been recorded by science, at least three new fish, a new bat and a giant rat, which may turn out to be the biggest in the world.” Read the Complete Story
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Rudolph Bench - 3 Seater - Bone - Cognac
139 700 SEK
Rudolph Bench Three Seater designed by Vincent Van Duysen is inspired by custom-made products that Vincent often produces in his work as an interior architect. The name Rudolph was derived from Rudolf Michael Schindler, a major protagonist of mid-century American modernism. This version of Rudolph is a free-standing stylish sofa in a three-seater size with upholstery in durable linen.
- Solid oak wood frame with details in aluminum. Upholstery in linen and cushion filling in hybrid foam.
Height: 72 cm
Length: 279 cm
Depth: 112 cm
Seat height: 43 cm

domain: artistic


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Doha, Qatar – Mohammed Ali, a restaurateur in Qatar’s capital Doha, tells a story about a female customer who would come to his shop every day with a flask to have it filled with karak tea.
One day, her driver brought the flask and said the woman was in a hospital ready to give birth. But she needed her karak.
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The next day, she herself showed up with her flask.
Ali’s restaurant is not an upmarket cafe, it’s a nondescript 65-year-old eatery on Doha’s Old Airport Road, so what inspires this loyalty? It’s the karak.
Karak is a sweet, milky tea made by boiling water, thick canned milk, tea leaves, sugar and cardamom (some places add saffron) together until it reaches just the right consistency, which varies according to the karak maker.
Everyone in Qatar knows what it is, and the country’s kaftheeriyas (cafes) serve thousands of cups of it daily, most costing just 1 riyal ($0.27).
Before the era of Instagram and social media influencers, finding a winning karak recipe, and having a good location, was the key to pulling in customers.
“The kaftheeriyas experimented with different blends of spices, milk and tea leaves to create flavours,” Ali said.
Walking into the shop is optional. You can honk your car’s horn and someone will be at your vehicle within seconds, ready to take your order.
Karak and samovar tea come to Qatar
How and when karak arrived in Qatar is still disputed, but the general consensus is that South Asian expats brought the milky tea with them as long ago as the 1950s.
Today, a lot of Qatar’s karak is made by people from the Moplah Muslim community of India’s North Malabar region, who were a land-owning, agrarian community.
“When agriculture went bust, youngsters from feudal families found the Gulf region as a haven where they could cash in doing any type of work away from home,” Rafeeq Thiruvalloor, a Malayalam writer from North Malabar, told Al Jazeera.
The same Malabaris brought samovar tea to Qatar.
Samovar tea, the more recent arrival which is gaining popularity now, and karak look the same but there are some major differences.
A karak, by default, is a strong tea, even the name sounds strong. Samovar tea is not strong by default, you have to request that, and it uses fresh milk whereas karak relies on thicker, canned milk.
With a standard karak, you don’t get many options when it comes to sugar levels. Many find karak oversweet and have to specify if they want a milder option.
In contrast, if you want your samovar tea sugary, you have to specify that in your order. Most samovar shops let you pick how you want your tea: strong, medium, light, waterless, well-beaten or unbeaten.
Before samovar, some karak tea shops served “fresh-milk tea” upon request – at double the price. There was also a “Sri Lankan tea”, simply a beaten version of karak.
Sajeer bin Abbas, a software engineer, said he stopped having tea at shops in Oman, where he worked for seven years, because the teabag-infused karak served there disgusted him.
“Now, samovar tea is one of the pleasures of working in Qatar,” he said.
No one remembers seeing a samovar tea shop in Qatar before 2014. Now, while the number is still shy of 100, you often see long lines forming outside.
By most accounts, Lordz Restaurant, tucked away in Al-Thumama’s Furjan Market 36, is Qatar’s first samovar tea shop. The shop is known as Sayyidinte Chayakada (Sayyid’s teashop) and its owner, 39-year-old Sayid Komban Chalil, said he launched the business in 2014.
He came to Qatar 20 years ago and worked at his father’s cafeteria in the southern city of Al-Wakra. Eight years ago, he brought a samovar, from Kozhikode’s Copper Bazaar in the Indian state of Kerala.
Until recently, Chalil says, his stencilled image with a “Sayyidinte Chayakada” logo was on the glass door but authorities asked him to remove it. The name exists on the shop’s website, on one of the inside walls and on the jerseys of three cricket clubs he sponsors.
Chalil, who comes to the shop now only in the evenings, said he was very active when he was setting up but owning a stable business helped him slow down.
On weekends, street cricketers flood his shop. He used to play for the Thumama Boys club and a shelf laden with trophies adorns one of the walls in the shop.
Until a recent repaint, Sayyidinte Chayakada was decorated with old Indian movie posters, giving it the look of old teashops in Malabar towns.
Samovar shops love their nostalgia. In Fereej Bin Mahmoud’s Chaya Kada, there are bicycles on the wall, old radios on display and a three-wheeled tuk-tuk rickshaw. New Plaza has a mural on the wall of a teashop in Kerala. In Asian Town’s Metro Restaurant, black and white photographs of a colonial Indian fort town adorn the wall.
Those suffering from homesickness can get a quick fix.
Chalil’s samovar is a barrel-shaped copper utensil that keeps 40 litres (10.5 gallons) of water boiling on a gas stove below a faucet. This is what is used to make the “decoction”, a potent sugarless black tea, and to keep milk simmering in an upper chamber.
Water is added through a hole on the top and milk heats up separately. The tea goes in the boiling water contained in a small fabric pouch, to keep the leaves from floating around in the finished tea.
If you want a cup of sugarless black tea, all it takes is about two tablespoons – 30ml (1 ounce) – of decoction added to 90-120ml (3-4 ounces) of boiling water.
Most samovar tea patrons, however, prefer milk tea. So the tea maker will add a ladle of simmering milk from a nearby stove and a spoon of sugar then he will “beat” the tea.
“The milk boiling on … top is a reserve. The tea-maker can’t always raise his hand to take it from there,” explained a tea-maker.
To beat the tea, the tea-maker pours it back and forth between a mug and a cup, raising and lowering his hand in a rapid, up-and-down movement to create froth. The consistency, foaminess and taste reach a new level with the beating, nearly impossible to replicate at home.
People watch the tea-beating pretty carefully. If the tea maker gets his hands really far apart, people call it “metre tea”, referring to the distance between the hands.
Beyond beating, the ratio of the ingredients, the heat dynamics of the stove,t the flavour of the decoction and milk, contribute to whether or not a tea maker is called a tea ustad (tea master).
Drinking tea at Lodz was Harshad Kuttipran, a samovar fan who likes exploring new places for tea and hopes to have a shop of his own.
His late father had teashops in India’s Andhra Pradesh and Karnataka states. Growing up in Kerala, he remembered that teashops as institutions for socialising, where patrons could read newspapers and listen to the radio. “The news would lead to heated political debates,” Kuttipran said.
Can samovar challenge karak?
While people like Chalil are optimistic about the prospects of samovar tea in Qatar, many reckon karak tea will remain on top.
In Madinat Khalifa’s Kismath, a restaurant that serves samovar, tea-maker Salman has no time to talk. The one thing he said is that he makes 700 cups of tea during his shift.
But karak has a steady and established fan base, Muhammed Shibli, general manager at Tea Time, a chain with more than 50 branches across Qatar, said.
“People have more than 10 cups a day. We will remain serving karaks and only karaks for the time being,” Shibli said.
A partner in the Zanjabeel karak chain said his branches would serve only karak. However, Dosa Street, his south Indian cuisine venture in the Ain Khaled area of Doha, serves samovar tea.
Personally, he prefers karak because he finds the samovar tea makers’ habit of putting another layer of decoction over the foam sometimes leaves a sour taste.
In neighbourhoods like Matar Qadeem (Old Airport), where the population is younger and where gyms and barbershops are open round the clock, samovar tea shops provide a sense of community, or “vibes”, as the residents put it.
Many branches of House of Tea, another chain, have recently drifted towards samovar tea, said Kuttipran, the tea fan.
“Still, I don’t think Qataris and other Arabs will like the samovar, which is also generally less sugary than karaks.”


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£120,000 Compensation Awarded in Hospital Negligence Case
A Hospital Negligence Claim Case Study - Client Situation
Medical staff at a hospital failed to detect a major heart problem in one of our client’s babies while she was pregnant with twins.
Given the nature and severity of the defect, medical staff would normally have proposed terminating the pregnancy in the case of the affected twin. However, as the congenital cardiac defect hadn’t been detected early enough in the pregnancy, the mother had to undergo an extended labour and an unnecessary second delivery.
Our client and her partner received no counselling, nor any warning, of probable difficulties. When their baby collapsed and needed cardiac resuscitation following delivery, clinical staff warned them there was little hope of survival, causing the parents significant psychological shock and distress.
Besides the anguish of the wrongful birth, both parents suffered significant financial loss, and will continue to do so as they care for their disabled child.
How We Helped
The baby’s parents contacted our team of Medical Negligence Solicitors, as they believed the hospital that cared for the mother throughout her pregnancy and delivery had failed to provide the expected standard of care.
Our Medical Negligence Solicitors agreed to take on their case, and in presenting the case argued that an accurate diagnosis of this exceptionally severe heart defect should have been made during the pregnancy. Our Solicitors also argued that given the severity of the defect and the complications this could cause, the family would have made the difficult choice to terminate the pregnancy of the affected twin, had they been given the option to do so.
Looking after the disabled infant, whose survival prospects are uncertain, has taken over almost every aspect of the parents’ lives, and has also had a knock-on effect for the healthy twin.
The medical negligence in hospital also had a considerable financial impact on the family. For example, the mother had previously been the main breadwinner in the house and would otherwise have returned to work. However, she was unable to do so due to her child’s ill health.
Our Solicitors sent a Letter of Claim to the Hospital Trust and it was subsequently admitted that a congenital heart defect should have been identified during ante-natal scanning. It was accepted that that under normal circumstances this would have led to a specialist referral and then a diagnosis.
After lengthy negotiations, the Hospital Trust offered a compensation settlement of £120,000 which was accepted by the family.
For additional childbirth case studies, see Birth Injury Claims.
For free legal advice call our Medical Negligence Solicitors
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Simpson Millar Solicitors are a national law firm with over 500 staff and offices in Billingham, Bristol, Cardiff, Catterick, Lancaster, Leeds, Liverpool, London and Manchester.