Adrian superintendent discusses 'Portrait of a Graduate' lesson plan, communications plans
ADRIAN — Nate Parker wants to make sure there is a continuous, two-way, open line of communication between himself and practically every stakeholder group throughout the Adrian Public Schools district.
The Adrian superintendent, who was hired as superintendent in January 2022, is still finding ways to better communicate with parents, businesses, members of the public, Adrian students and staff, and others about the learning experience at Adrian Public Schools.
Last week, during the Adrian Board of Education’s April 24 meeting held inside the media center at Michener Elementary School, Parker delved into the specifics of certain lesson plan updates and engagement opportunities between himself and students, families and the community that are in the pipeline.
With the 2022-23 school year concluding in early June, Parker said he has scheduled an entire day in each of the district’s six buildings where staff members can talk with him for 15 minutes or longer. Parent-teacher organizations and advisory groups at the district’s buildings can come together at the district level throughout the year, he said, to provide updates about what’s happening in those buildings.
Something in the works, he added, is the potential for a district-level student voice group that could share its thoughts and ideas with Parker throughout the school year.
Feedback forms will also be provided for staff members for additional feedback, ideas, thoughts, concerns and questions, he said.
“This two-way, open line of communication needs to be built on a regular basis,” Parker said.
Beyond hearing from stakeholders about their thoughts and concerns, Parker said he also wants to hear about the day-to-day experiences in school for students, staff and stakeholders.
All this communication, he said, will include information about the district’s “Portrait of a Graduate” lesson plan. The idea behind this lesson plan, he said, should allow students graduating from Adrian to leave their general education years with more than just a high school diploma in hand.
Instead, he explained, students should be expected to graduate with a love for learning, becoming better critical thinkers, researching and coming to their own conclusions, and being able to find the truth in subjects.
The critical thinking aspect, he used as an example, needs to be developed and reflected within the district’s curriculum.
The process for the “Portrait of a Graduate” plan started during the week of April 17 and a kickoff to the program began today for central office staff and building administrators in which they are to be coached about how to implement the program and then how to discuss it further with other focus groups and school stakeholders, Parker said.
“This is not something you just do and check the boxes for,” Parker said. “This is a process and you’re probably never completely done.”
June 1 is the final professional development day of the 2022-23 school year. That day, Parker said, will allow staff to provide input on the proposed program and to understand the development of what the school district wants its graduates to strive for.
Stakeholder surveys will be developed and will be sent out. Focus groups will also be formed. Ultimately, Parker said, a school board workshop will be held, too, as the board has a big say in what it wants to see in a student’s education, he said.
“We’re not rewriting our mission statement,” Parker said. “That is our mission statement. This is another piece of the puzzle.”
The “Portrait of a Graduate” program is beyond teaching students the basics of learning and how to read, write and do well in math and science, for example. It also incorporates the importance of skills and trades, Parker said.
“Some students of ours want to be garbage truck drivers, while other students want to design the garbage truck,” he said. “We need to make a constant effort of meeting with each student.”
Some of the work on the lesson plan will be done at the end of the school year and more work will continue over the summer, he said. The goal is to approach the fall 2023 start of the school year with a plan that is finalized and ready to be woven into Adrian’s lessons, curriculum and instruction.
In other business
The Adrian Board of Education at its meeting also:
• Approved the retirements of Ann van Stavern, media specialist, effective June 3; Jill Roberts, teacher, effective June 3; Jeff Peterson, administrator, effective Feb. 28; Ivy Hutchison, Head Start, effective June 30; and Laurie Pontius, paraprofessional, effective April 19.
• Approved the hiring of Laura Turner as a program assistant at Drager Early Education, effective May 1. Turner, according to an executive summary from the school board, has three years of experience working in the administrative field. She has a bachelor's degree in business administration from Eastern Michigan University.
• Approved a bid of work for the upcoming bathroom/toilet remodeling project at Springbrook Middle School to Spieker Construction at a cost of $105,000. The funds to pay for this work will be paid out of the district’s capital projects and technology fund, business manager Dan Pena said.
• Accepted a list of donations, including four donations totaling $1,300 to the baseball/softball seating project; nearly $900 for the Families in Transition program; $1,000 toward March is Reading Month activities; $250 to the athletic activity fund; $784.62 to the boys baseball team; $500 to the girls basketball program; $1,300 to the boys track and field team for pole vaults; the city of Adrian donated $432.50 for the Maple Frost Polar Plunge, which was held in February as a fundraiser for certain community programs and nonprofits; and Michael Ballard, school board trustee donated $2,500 to the robotics team.


The rule of thumb for all pure wool products is to wash in cold water and gently wring or use the delicate cycle and low spin on your washer. It's no longer necessary to handwash woolen items, as most washers now have a delicate agitation cycle and low spin feature. Heat can and usually does shrink woolens, reducing them in size and ruining their appearance. Cold water and gentle washing will help keep your woolens in good condition.
We are recommend you can use for your woolen washing, specially formulated detergents like LANOLIN will further protect and keep your woolen products looking terrific. I've used LANOLIN for years and highly recommend it for all your woolens and delicate fabrics.
You can wash woolen 1-3 times per year.
Lanolin is the smelly pale-yellow natural oil found on sheep’s wool. As a waste product in wool processing, it's also known as wool oil, wool wax, wool fat, or wool grease. It's a natural water-repellant, the function of which, it's not too hard to guess, is to waterproof the sheep. Lanolin also has anti-fungal and anti-bacterial properties that protect the sheep's skin from infection.


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Horse Country Campers Club is pleased to join forces with Open Trail to provide even more value to our members. Open Trail is an on-line trail repository, created to document actual trail usage in the US and Canada and arm organizations that maintain and advocate for horse trails with essential data to fight for our National Treasure... The Open Trail.
Horse Country Campers Club is a membership-based discount camping club dedicated to horse camping and trail riding at some of the most beautiful horse camping destinations in North America.
"Open Trail" was developed to support the creation of interactive trail maps for our favorite riding trails, and most importantly, a way to share them with other riders.
Joining forces with Open Trail was a logical choice to provide more value to our members and to support the vision and mission of protecting and saving horse trails for future generations says Horse Country Campers Club President Larry Davis.
By combining forces, benefits extend to both Open Trail and Campers Club members via significant savings!
With tremendous savings off combined Open Trail/Campers Club memberships, our customers get to take advantage of camping discounts at participating campgrounds in Canada and the USA along with the interactive trail maps provided via the Open Trail website says JR Hull, Founder of Open Trail.
For more information and to sign up today, visit www.horsecountrycampersclub.com, call us toll-free at 1-888-591-1952, or email us at firstname.lastname@example.org.
Open Trail started as a modest project in 2011 to develop interactive trail maps for trail riders to use and share with other riders. Since it's launch in 2014 "Open Trail" has over 12,500 trail miles uploaded by over 400 members and is growing everyday. Open Trail's long term goal is to provide the largest repository of horse trails in the U.S.
For additional information or media inquiries, please contact:J.R. Hull- Founder
Horse Country Campers Club is discount camping program offering members discounts at horse-friendly campgrounds across North America. Members can also take advantage of our fast-growing network of suppliers from the equine and travel industries with special incentives and discounts on a range of products and services. Horse Country Campers Club is owned and operated by USA Horsesource Inc.
For additional information or media inquiries, please contact:Larry Davis - President

domain: travel


Kozan's signature Jane Jacket has been revamped in a gorgeous knit with a dimensional weave. Masterfully constructed with a set-in shoulder, zipper-front closure, high-low hemline and slit pockets at the hips. Tailored through the shoulders and bust with a subtle flare to the hips.
65% Viscose, 30% Polyester, 5% Spandex.
Machine wash cold on gentle cycle. Hang dry.


text: BLUEBERRY – (Vaccinium Corymbosum) Blue Crop – Medium to large fruit with consistent yields and adapts well to various soils. Main cultivar for commercial and u-pick farms, high bush. Northland – Early to mid-season fruit with consistent production. Grows in any soil and very hardy. Fruit is sweet throughout growing. High bush.

domain: agronomy


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IN CASE YOU MISSED IT: 5 key stories from September 16
Here are five Fastmarkets MB stories you might have missed on Monday September 16 that are worth another look.
Brazilian multi-metal and mining company Vale has announced plans to build a further two nickel smelters in Indonesia in joint ventures with China and Japan, the deputy chief executive officer of Vale Indonesia said in a Saturday September 14 news interview.
Newmont Goldcorp has suspended production at its Peñasquito mine in Mexico, which is again being blockaded by the local community there, the company said on Monday September 16.
Copper miner PT Freeport’s export license for copper concentrates has been tripled by the Indonesian Energy and Mineral Resources Ministry for the March 2019-March 2020 period, Fastmarkets has learned.
Major Vietnamese integrated steel producer Formosa Ha Tinh Steel Corp has lowered its offers for hot-rolled coil to be shipped and delivered in November by $51 per tonne amid a weakening international market for the flat steel product.
The active contract price for aluminum on the Shanghai Futures Exchange may rise as high as 15,000 yuan ($2,128) per tonne by the end of October 2019 on the back of tightening supply, market participants have told Fastmarkets.

domain: news


Spokane Community College’s automotive expertise program is an industry leader in coaching technicians for profitable careers in the automotive area. YASA’s motors and controllers are ideally fitted to purposes where house and weight are essential including automotive, industrial, marine and aerospace. Through the second semester, college students are encouraged to participate in a piece research program whereas receiving highschool and college credit for his or her time on the job”. Most service technicians work full time, and plenty of work evenings or weekends.
By 1905 gasoline vehicles had been more common than steam or electric vehicles as a result of they were simpler to make use of and could travel further with out adding fuel. My job was to make a few of the elements that go into the 114-hp everlasting-magnet motor that can energy electrified Chevy Sparks when they go on sale someday in 2013. The DC brush motor is without doubt one of the easiest motors in use immediately.
The magnetic area on the rotor is either generated by current delivered by way of slip rings or by a permanent magnet (PMAC). Rio Hondo College is dedicated to the success of its numerous students and communities by providing dynamic educational opportunities and resources that result in levels, certificates, switch, profession and technical pathways, fundamental expertise proficiency, and lifelong studying.
Collision protection pays for damage to your automobile no matter who’s at fault. We provide honest and transparent pricing and supply estimates upfront for a whole bunch of companies on hundreds of automobiles. Power drive could also be built in to the motor management IC or it might use external MOSFETs for increased drive present. An electric automobile had a battery that powered a small electrical motor, which turned a drive shaft.
The policyholder agrees to pay the premium and the insurance coverage company agrees to pay losses as outlined within the coverage. Chapter 5 explains and predicts the pattern to a number of traction machines in autos. Whether or not you want regular upkeep or a transmission changed or rebuilt, All About Auto Service is your one-cease car store. Presently, the insurance coverage company will have a look at motorized vehicle data to see how many accidents or tickets a driver has received.


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The “Fira del Llibre”, a feast of books and culture for a...
The “Fira del Llibre”, a feast of books and culture for all ages
Are you preparing a trip to Valencia? Note this plan down! The great literary yearly event comes again to the city. From 26th April to 6th May, the great classics, recent releases and the most treasured rarities will gather in the Gardens of Viveros in an authentic festival of art, literature and entertainment.
In 53 Fira del Llibre de València, you will have at your disposal thousands of books from all genres, from the great bestsellers to technical and entertaining publications, passing by the new releases, where the literature addressed to children and young people take more presence and strength. Whatever your style, you will find it here.
During the event, there will be activities related to the world of books, reading and culture: presentations of new products, signatures of books by their authors, meetings with writers, readings and recitals, animations, storytelling workshops, theatre, concerts… There will also be a space for the illustrators of Valencia, with an exhibition and activities related to this sector. It is never too late to learn something new.
Take your books and enjoy València. From the Gardens of Viveros, where the fair is held, you will be able to go down to the river Turia and discover the true green lung of the city. There is no better place to read surrounded by full nature.

domain: literature


text:
This is a Montreal SUPERGROUP of sorts. Members of The Scat Rag Boosters, The Daylight Lovers, Les Sexareenos and the Spaceshits.The Del-Gators are led by the tantalizing songwriting tandem of pianist CocoButter Khan and guitarist Oily Chi (Spaceshits). Those familiar with the Sympathy roster will be pleased to find Dorrito Dan (Sexareenos, Spaceshits) on drums, Choyce (Sexareenos, Daylight Lovers) on bass, and finally, guitarist extraordinaire Cheddy (Scat Rag Boosters). The album's line-up is completed by vocalist Jenna Roker.
Oily Chi - guitar harp vox
coco butter khan - piano - piano, vox
choyce - bass ,vocals
cheddy - guitar, percussion, vox
dan pedro dorito - drums vocals
jenna - vocals
1. get down (and get stupid)
4. move mr. man
5. bompa my bones
6. wiggin' out
7. cockroach crawl
9. car troubles
11. lay it down
12. cruel game
|THE DEL GATORS
LP: VR1211 (EAN CODE: 7640111760191)
Here they come, straight out of the swamp, with 13 cut-throat killer songs, the dirtiest R&B band to ever creep out of the mudpit- THE DEL GATORS. Born from the greasy gutter love of guitarist Oily-Chi and pianist Cocobutter Khan, the Del Gators bring together the burnin' sound of guitarist extraordinaire Cheddy, the
wailin' thunder of show Woman Little Honey dee, finger lickin' bassist Choyce and last but not least the fabulous Dan Pedro Dorito, poundin' on the skins. Put together two wild' shakin' amazon beauties and 4 cursin' dirty' boys and there you have it, the bumpin' grindin' sextet of the Del Gators, leading you straight to the Holy Ghost. Their one of a kind Rock'n'roll show will leave you blinded, drippin' with saucy boogie woogie piano licks, hot howlin' women and voodoo guitars, all backed up by the cave man pound down.
Come one, come all, come on and get pounded down by the del Gators!!!!!!
recordet by Jim Diamond (Andre Wiiliams, Dirtbombs...)

domain: entertainment


Gov. Paul LePage tried to exert pressure on Maine’s congressional delegation Wednesday by urging Mainers to demand that federally funded National Guard employees in Maine be put back to work. According to LePage, more than 300 Mainers in the Air and Army National Guard were affected by the shut-down of the federal government on Tuesday. […]
Health care revolution within reach (minus the revolution part)
State & Capitol
Poverty isn't eliminated by threatening the poor
Has the addiction epidemic become accepted population control?


text: However, the diameter of the lens (known as the aperture) is what determines much of a telescope’s power, and the next two types of telescopes allow for a larger one. When it comes to telescopes, there are two types; the reflecting and refracting telescopes. StarGazingPro.com is compensated for referring traffic and business to these companies. Simply translated: “The larger the primary objective lens or mirror, the better the potential you have for seeing the object.”. Refracting telescopes have several benefits over other telescopes: Because the inside of the tube is sealed at both ends (with lenses), refracting telescopes don’t suffer from dirt inside. These type of telescopes were very popular well into the late 19th century, and they may be good for historical purposes or if one is looking for a cheaper tool, then this might be a good option. Some telescopes come with a prism adaptor that bends the light through 90 degrees, so looking through the eyepiece is much more comfortable. Reflecting vs. Refracting Stargazing Telescopes, Stargazing For Dummies Cheat Sheet (UK Edition), 9 Stargazing Marvels to Look For under a Dark Sky. Reflecting telescopes use mirrors to gather the light. However, refracting telescopes are longer and more unwieldy than reflecting telescopes, and can suffer from something called chromatic aberration, where a rainbow of colours appears around the image. Reflecting vs Refracting Telescopes – Which is Better? Specifically, the glass lens can expand, contract, and warp which will distort any image viewed through it. Blog General / By Administrator Which Is Better: A Refractor Telescope or a Reflector Telescope? StarGazingPro.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com. Refracting telescopes use lenses. The answer to this question would ultimately depend on your needs. Refracting vs Reflecting Telescope. Which Is Better: A Refractor Telescope or a Reflector Telescope? This site is owned and operated by StarGazingPro.com. The refractor type uses a series of lenses to accomplish this. For example, a mirror frequently exposed to this harsh environment could be less reflective within years, or put it in a different way, its ability to reflect light decreases. One of the most common types of reflecting telescope is called a Newtonian reflector, named after the man who invented it, Isaac Newton (of falling apple fame). Reflecting telescopes are popular due to their versatility and the fact that they’re cheap to make. There are different kinds of reflectors, but in general the refractors all follow the same basic design. This objective lens is convex shaped and coordinated with an eyepiece so that whatever is being looked at will be amplified enough and gather more detail for you to see. Probably the greatest improvement of these over the older variety is that they allow for a much greater aperture so that these telescopes can be of a higher power in many cases. The distinction between the two is in how they manipulate the incoming light in order to magnify the image. That is one of the reasons that they are practically ubiquitous when it comes to astronomy and the research within that field. If one of your desires is to use the telescope for occasional viewing of land objects (e.g., buildings, mountains, beaches, boats, landscape), then I have found that a Refractor telescope works best for this purpose. Aside from their step price, refracting telescopes introduced many challenges, such as presenting distorted images caused by the material used or lens weight. This lens gives the telescope a slightly wider field of view. The first thing to consider here is the aperture. This is why they require to be manipulated with precision and attention. Cassegrain reflecting telescopes have all the same advantages as a Newtonian reflector, plus they’re much more compact. Reflecting vs Refracting Understand the advantages of reflecting telescopes compared to refracting telescopes, in terms of: chromatic aberration; very long focal lengths; using large aperture objectives; use of multiple mirrors; The majority of professional and amateur telescopes are reflectors. – The 3 Things You Must Have, The telescope construction and material quality, The sturdiness and stability of the tripod, The quality of the telescope mount and the ease of use, Other accessories (e.g., included lenses, accessory tray, finder scope, storage/carrying case), Supporting features (e.g., computerized locator), How does the buyer plan to use the telescope. A basic Refractor telescope consists of 1) a tubular body; 2) an objective lens, and 3) an eyepiece.eval(ez_write_tag([[250,250],'stargazingpro_com-medrectangle-4','ezslot_1',106,'0','0']));eval(ez_write_tag([[250,250],'stargazingpro_com-medrectangle-4','ezslot_2',106,'0','1'])); Compare this to a Reflector telescope which consists of 1) a tubular body; 2) an objective mirror; 3) a viewing mirror; 4) a viewing mirror holder, and 5) an eyepiece. Additionally, the cost for producing a quality lens greater than 4 inches in diameter becomes increasingly more expensive because they require more advanced manufacturing techniques to help overcome some of the shortfalls. When you’re ready to invest in a stargazing telescope, start by looking at the different models of telescope tube – the bits with the optics in. You can find quite a few different designs. Refracting telescopes use lenses to collect and focus the light, just like binoculars do. Because of their design, Cassegrain reflectors can be more compact than their Newtonian cousins, because the light is ‘folded’ twice inside the tube, making two journeys rather than one. StarGazingPro.com also participates in affiliate programs with Bluehost, Clickbank, CJ, ShareASale, and other sites. One of the advantages of this type is that it does not produce the same chromatic aberrations that the refractors are known for, but there are still newly introduced focus issues depending on the total quality of the device. Reflecting telescopes are cheaper to make. It then travels down the length of the telescope to the eyepiece lenses, which is where the magnifying happens. He has been the recipient of the 'Campaign for Dark Skies' Award for Dark Sky Preservation, and he was nominated for the Arthur C. Clarke Award for public science engagement. Refracting and reflecting telescopes each have their unique uses. So here’s a quick guide to help you decide the better telescope for your purpose. Reflecting telescopes don’t suffer from chromatic aberration. The answer to this question depends on what you are seeking from a telescope. The light enters the tube and reflects off a curved mirror (called the primary mirror) at the other end, before bouncing back up the tube to near the top where it reflects off a smaller mirror (called the secondary mirror), which bounces the light out of a hole in the side of the telescope where you attach your eyepiece. Reflectors have several advantages over refractors. Cassegrain telescopes can be half the length of Newtonians. This setup can make looking through the eyepiece a little tricky, especially in the bigger Newtonian telescopes, where you may need a step or small ladder to get high up enough to see through the eyepiece. Because the tube is sealed at both ends, refracting telescopes don’t have the problem of air moving about inside the tube, and so have sharper, steadier images. In Newtonian telescopes, the tube is open at one end. This setup can make observing through a refracting telescope quite uncomfortable, especially if you’re pointing your telescope high in the sky, because you may have to stoop and crane your neck to see through the eyepiece. Lens coatings and a longer telescope tube (which increases something called the focal length) can help reduce this problem. Another variation on the Newtonian reflector theme is the SchmidtCassegrain, in which a thin lens is placed over the front of the telescope tube. As a result, a person can research and find a Refractor telescope that is less expensive than a comparable Reflector telescope. If you want to view: From a general viewing perspective Refractor telescopes work well for viewing brighter objects like the moon and planets. Whereas Reflector telescopes are best suited for observing dimly lit deep-sky objects, like low magnitude stars, clusters, nebulas and the like.eval(ez_write_tag([[728,90],'stargazingpro_com-box-3','ezslot_0',104,'0','0'])); With that said, let me know state that telescope technology, manufacturing processes and a myriad of other factors have resulted in a blurring of the distinction between the two different types of telescopes. When it comes to a physical construction cost comparison between a Refractor telescope and a Reflector telescope, there is one obvious fact: The construction of a Refractor telescope is relatively easier and simpler than a Reflector telescope. In fact, you can think of a refracting telescope as one half of a giant pair of binoculars. The benefits of Newtonian reflecting telescopes over other telescopes include the following: Because the mirror can be fixed onto a metal plate, reflecting telescopes can be much bigger than refractors. 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domain: hobby


text:
The Grand Forks Herald recently featured the story of Lake County Internet efforts. We’ve talked about the project before – which is an ARRA-supported project intended to bring fiber to are.
The incumbents fear that the ARRA loan is too much and that taxpayers will end up paying back the hefty loan…
County officials estimate they need 65 percent of households to subscribe in order for them to repay their loan.
Larson, of Medicacom, doesn’t believe that’s realistic. He said to reach that number, the county will have to sign up a lot of new subscribers in rural areas, as well as take the majority of customers away from existing providers in larger towns like Two Harbors.
“It’s going to fail,” he said. “I don’t know how else to say it more plainly than that to the taxpayers of Lake County. It’s going to fail, and they’re going to have to pay it back.”
Local leaders feel that the County needs the fiber to increase safety and economic opportunities…
But Lake County Commissioner Paul Bergman said Mediacom has not improved or expanded its service, and could have itself applied for stimulus funds.
Bergman said the new network is critical to improve the region’s public safety. Twice in the past two years, including during recent flooding, the county lost 911 emergency service. He said a network with a backup line like the one the county is building will maintain service even if a line is cut.
He said the county also needs the new network for economic development.
“One of the things that I hear at class reunions is ‘I’d love to move back home if I had a job,’” Bergman said. “Well, here we bring in a whole new avenue where people, their headquarters might be in Minneapolis or Hong Kong, they could still work out of their house on a shore of a lake here in Lake County.”

domain: economics


text:
Cancer, Drugs, and Alcohol
CANCER, DRUGS, AND ALCOHOL
The relationship between cancer and drugs, including alcohol, has several aspects. One is the question of carcinogenesis; that is, whether alcohol and other abused substances cause cancer. Another is the relationship between prescription medications and cancer. A third is the complications of cancer treatment in patients with a history of substance abuse.
The likelihood of a substance to cause cancer is called carcinogenicity; this is determined in several ways. The first is to see if cells grown in vitro (in a test tube) with the potential carcinogen develop cell-structure abnormalities in the new-grown cells. The second is to see if the substance will result in cancers in animals. The third is to look at the clinical course of a disease in a human patient. Finally, the outcomes in a group of people exposed to the substance will be compared to outcomes in those not exposed—either by following the natural course of history in a population through time in cohort studies or in case-control.
In spite of these methods, however, identifying carcinogens is complex and difficult. One reason is the long time delay between use of a carcinogenic chemical and the appearance of cancer symptoms; intervals of 20-30 years are not unusual. As a result, carcinogenic effects are rarely detected in early studies of new medications. Secondly, carcinogenesis appears to be a multistep process involving environmental, nutritional, and genetic factors as well as use of a carcinogenic drug.
Carcinogens are classified as genotoxic or epigenetic. Genotoxic carcinogens act directly on the DNA in human cells, in effect producing abnormal cells. Almost all identified drug carcinogens, however, fall into the second category, the epigenetic carcinogens. These substances encourage the proliferation of latent tumor cells in a tissue or organ.
DRUGS OF ABUSE AND CANCER
Animal data do not show that administering Alcohol alone causes cancer although there is sufficient evidence for the carcinogenicity of acetaldehyde (the major metabolite of alcohol). When alcohol was administered to animals who were also exposed to known carcinogens, the animals who were given the alcohol had a higher rate of tumors of pituitary and adrenal glands, pancreatic islet cells, esophagus, and lungs. They also had higher levels of liver-cell (hepatocellular) carcinomas, liver angiosarcomas, and neoplastic nodules of the liver, as well as benign tumors of the nasal cavity and trachea.
Cancers of the Digestive Tract. Epidemiological studies in humans have shown a causal relationship between alcohol consumption and cancer of the digestive tract, primarily cancer of the oral cavity, the pharynx (nasopharynx excluded), and the larynx—all two to five times more likely in alcoholics; the esophagus—two to four times more likely; and the liver—liver cancer was increased 50 percent, with primary liver cancer increasing twofold to threefold. These findings persisted, even after adjusting for the effects of smoking, with the relative risk for cancer increasing with the amount of alcohol consumed.
There may be a possible causal link between alcohol, especially beer, and cancer of the large bowel. The risk for colon cancer was increased between 15 percent and threefold depending on the study; that for rectal cancer was increased up to twofold. Unfortunately, these studies did not control for differences in diet.
The mechanism of carcinogenic action appears to be that alcohol acts as a local irritant to the upper gastrointestinal tract, whereas chronic excessive drinking affects the liver, because of the accumulation of the alcohol metabolite acetaldehyde.
Breast Cancer. A strong association exists between alcohol and breast cancer, and there appears to be a dose-response relationship with an apparent relative risk of 1.5 to 2. This relationship holds even after controlling for a number of other factors known to affect breast cancer. As the full etiology (cause) of breast cancer is not yet known, an as-yet-unrecognized factor may account for some of these findings. Overall, it has been estimated that as many as 10 percent of all cancer deaths are due to alcohol.
Tobacco and Illicit Drugs.
The role of Tobacco as a carcinogen is well established and is discussed elsewhere. The role of other drugs as a cause of cancer is still unclear. Some drugs may have a role in cancer development because of mode of administration or degree of carcinogenicity. In vitro studies have shown mutagenic properties in a number of drugs—Lysergic Acid Diethylamide (LSD), Opium and its derivatives such as Mor-Phine, synthetic narcotics such as Methadone, and some compounds found in Marijuana. There have been clinical reports of cancers in the respiratory tract, primarily the lungs, in heavy marijuana users, of the nasal passages in cocaine users, and in a number of organs in LSD users. Higher rates of esophageal cancer have been reported in opium smokers.
PRESCRIPTION DRUGS AND CANCER
Very few drugs that are suspected of causing cancer in humans are used in contemporary medical practice. Those that are, however, fall into two significant categories: alkylating agents that are used to treat cancer; and birth control pills and other hormone preparations.
These antineoplastic drugs include busulfan (Myleran), used to treat leukemia that has not responded to other drugs; cyclophosphamide (Cytoxan), an immunosuppressant used to treat ovarian cancer and malignant lymphoma; melphalan (Alkeran); ifosfamide (Ifex), used to treat testicular cancer and Ewing's sarcoma; cisplatin (Platinol), a drug derived from platinum; and chlorambucil (Leukeran), used in the treatment of leukemia and Hodgkin's disease. All of these drugs have serious side effects ranging from liver toxicity to fibrosis of the lungs, as well as carcinogenic potential. Cyclophosphamide in particular increases a patient's risk of secondary cancers for several years after it has been discontinued.
Synthetic Hormones and Steroid Preparations.
The natural and synthetic estrogens used for contraception and for postmenopausal hormone replacement have been associated with an increased risk of uterine cancer. As of the late 1990s, these estrogens are usually combined with progestins, which appear to lower this risk. Diethylstilbestrol (DES), which is used to treat menopausal symptoms and advanced cancers of the breast, may cause vaginal or cervical cancer in women whose mothers took DES during pregnancy. Oxymetholone (Anadrol), a steroid related to testosterone, is reported to increase the risk of liver cancer.
SUBSTANCE ABUSE AND CANCER TREATMENT
On the one hand, Narcotic and psychoactive drugs have an important role in cancer treatment. Cancer patients have used Cannabis sativa (marijuana) to reduce the nausea associated with chemo-therapy. LSD has been used in treating psychological disturbances associated with cancer. Although it was once feared that cancer patients would become addicted to opioids given for pain control, a recent study showed that of 11,882 cancer patients with no prior substance abuse history, only four became addicts after treatment with opioids.
On the other hand, preexisting abuse of these same substances complicates cancer treatment. A history of substance abuse may shorten a cancer patient's life expectancy and undermine the effectiveness of palliative care. Ongoing substance abuse disrupts the patient's relationships with physicians and other caregivers. As of 2000, the National Cancer Institute has issued guidelines for the clinical management of cancer patients with substance abuse histories. These guidelines include evaluation and treatment of comorbid psychiatric disorders, evaluation of the patient's tolerance of drugs, and monitoring of hospital inpatients.
(See also: Complications: Immunologic )
Beers, M. H., & Berkow, R. (Eds.) (1999). The Merck Manual of Diagnosis and Therapy, 17th ed. Whitehouse Station, NJ: Merck Research Laboratories.
Breslow, N. E., & Day, N. E. (1980/1987). Statistical methods in cancer research, vol. 1, The analysis of case-control studies; vol. 2, The design and analysis of cohort studies. Lyon, France: World Health Organization (IARC Scientific publications no. 32 and 82).
Hanks, G. W., & Justins, D. M. (1992). Cancer pain: Management. Lancet, 339 (8800), 1031-1036.
Hardman, J.G., & Limbird, L. E. (Eds.) (1996). Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed. New York: McGraw-Hill.
Medical Economics Company. (1999). Physicians' Desk Reference, (PDR), 53rd edition. Montvale, NJ: Author.
National Cancer Institute. (2000). Substance Abuse Disorder and Supportive Care. Bethesda, MD: Office of Cancer Communications.
Wilson, B. A., Shannon, M. T., & Stang, C. L. (Eds.) (1995). Nurses Drug Guide, 3rd ed. Norwalk, CT: Appleton & Lange.
World Health Organization. (1988). Alcohol drinking—IARC monographs on the evaluation of carcinogenic risks to humans. Lyon, France: World Health Organization International Agency for Research on Cancer, vol. 44.
Revised by Rebecca J. Frey
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domain: medical


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I've read a lot of reviews over this game, and I've noticed one thing: Most of the people who give the game low ratings or harshly criticize it are people who have played the PS2 originals. This seems to be the case with A LOT of the reviews. Here's my two cents.
I played both Silent Hill games on this. Let it be noted, I never played the PS2 originals, so all of this was entirely new for me. Needless to say I enjoyed it extremely. I was happy to finally be able to play the two most critically acclaimed SH games, now in HD.
Like the title says, if you're a newcomer to Silent Hill in general, or if you haven't played SH 2 and 3 yet, this collection will be your cup of tea. If you played the originals on PS2, chances are you aren't going to have as much fun, because you'll constantly be comparing it to the PS2 version. That's just my opinion though.
I did enjoy both games a lot, the HD looks very nice, and even though there were a few glitches here and there, they weren't anything to ruin my experience playing these amazing games. The story to both was great, the gameplay was good, the music and sound were both amazing, and the graphics look wonderful and have a gloomy feel to them, as Silent Hill should.
Like I said, I played the HD collection without ever having played the original SH2 and 3, so that might be why I enjoyed it more than some people. Definitely satisfied me and gave me some good scares.
posted by clovelady (COLORADO SPRINGS, CO) Apr 2, 2012
Member since Feb 2012
Not a whole lot can be said about this game. Controls are archaic, lags a bit, but man. Venturing through the storylines of my 2 favorite entries in the Silent Hill franchise was just as fun this weekend as it was the first time I played them years ago. As always, Silent Hill 2 remains my favorite entry and the ending almost always brings an emotional response. Game development at it's best!
What can I say about Silent Hill 2 and 3, they are both probably the two most challenging games I've ever played. Not because of the action, but because the puzzles are so intense they make your head spin. These are the first to Silent Hills I played from the franchise and I have to say that they are two of the most scariest games I've ever played. The in game play definitely messes with your mind at some parts to the point where you don't know whats going on or what your supposed to do. I wasn't too fond of the controls when I first started playing the game, but after a while I got used to it and both of these games ended up being great games to play in the long run. Saying Silent Hill is scary is a huge understatement. These are two of the most creepiest and horrifying games you will ever play. This is survival horror at its best. I highly recommend this to anyone interested in trying out the Silent Hill franchise or is a fan of survival horror.

domain: game


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An excellent Winning On the internet poker Strategy Regarding Web gambling establishment Playing and also Steeds Racing
What do gambling establishment gaming, equine racing handicapping, lottery games, black jack, online poker, sports gaming all the things games of probability share? You absolutely are best matched if you thought betting. Being able to take the chance of money on those activities, sporting activities, tasks is exactly what each of them have in prominent. It is the chance that creates them more enjoyment to see as well as also take part in. Let’s face that, sitting from a kitchen table and playing cards may be delightful, but winning cash creates it to be a bargain much more fun. Viewing horses race down the extend can be exciting, yet much more so if you have several cash riding on a solitary including them.
There is some point called, “beginner’s luck, micron that plenty of people own experienced. How to access the hidden wiki occurs anybody initial attempt a computer game or on your first trip to the competition track. It seems that while you do not really understand what you are doing, you win money. That will certainly can be an excellent intoxicating experience that departs you intending to come once more along with experience it one more time along with again. Actually, you can determine that in case you can just find out more regarding the activity or activity, you can win even more. That is when the trouble truly will start, considering that as they mention, “A little knowledge can certainly be a harmful thing. micron
It is definitely wise to understand virtually any type of game or sporting activity you take place to be wagering on, yet understanding the video game or perhaps sporting activity isn’t actually just how you make earnings. What you should totally grasp is probabilities, percentages, as well as have some sort of money administration technique. It in truth has 2 components, often the “return of your particular investment, micron for instance, the specific thirty bucks to gain any person placed on a pony, and also a “return on your cost, really well indicating a portion concerning what you took the chance of, just merely like a financial institution offers interest on what you put in the financial institution.
To get some equine gamers with each other with sports gamblers, 10% will be thought about a good give back concerns financial investment decision. In most instancves typically the profit comes from an individual or even 2 big hits as well as there are a great whole lot of ups and also downs (gaming for a new living is not for the weak hearted).
If any person are wanting to earn money from betting, my ideas is to continue in addition to discover the game, however ensure you fully grasp the probabilities and also even betting because that is exactly how one can15484 actually reveal a revenue. An excellent beginning holdem poker casino player should understand Holdem texas hold’em Leads plus Percents and can rapidly come to be a new money player by understanding a good basic technique like Power Point Casino Poker. Whether the idea is understanding pot potential customers, card monitoring strategy throughout blackjack, or watching this toteboard and also understanding the way to make use of the costly to your advantage, it’s all worrying the odds along with getting good bets.
You will certainly discover individuals as well as females that are very great at moose racing handicapping as well as finding winners and also yet they go home from the track viewing as a loss due to the fact that these individuals really did not know how to assist make their wagers around the most effective means. Finding a winning horse or attracting an excellent send texas hold’em is not sufficient. You will need to recognize just how to assist discover an excellent assumption. Excellent bets with some sort of positive hope are just how some individuals be onward on gambling establishment gambling enterprise, holdem online poker, blackjack, equine rushing handicapping, sportsbetting and also lotteries. Whilst you might like this sport, discovering to have a passion for great wagers and being in a placement to be able to leave from unprofitable wagers can make you a champion.
Charge Peterson has been the expert horses player and card individual for many years. His contemporary techniques had actually been developed by contemplating outside the house the box. In the very own ideas, the effect of “A life very well squandered.” Costs remains to be instructing the essentials of video gaming for years.
For you to see most of Bill’s horseracing handicapping treatments at Pony Competing Burdening “No 1 can make you won, although learning the basic principles and a few little known methods as well as strategies may improve you closer to your desire for making a profit at your favored game. Use my procedures and personalize them to suit your very own style as well as any individual will certainly lead 99% of the crowd. “
Let’s face that, resting from a kitchen table and playing cards might be delightful, however winning money creates it to be a great deal a lot more enjoyable. To obtain some equine gamers together with sports gamblers, 10% will be considered a great offer back concerns investment decision. A good start holdem texas hold’em casino player ought to recognize Holdem casino poker Leads plus Portions as well as can swiftly end up being a new cash money player by mastering a good straightforward technique like Electrical power Point Casino Poker. Finding a winning pony or drawing a good submit casino poker is not sufficient. Whilst you might like this sport, discovering to have an enthusiasm for great wagers and also being in a setting to be able to stroll away from unprofitable wagers can make you a champion.


Clean Hydrogen Leader BoostBoxH2 Announces Results of Independent Testing Averaging 10% Diesel Fuel Savings Per Gallon and 70% Reduction in Emissions
Boulder, CO. – BoostBox H2, www.boostboxh2.com, a Boulder, CO based Clean Hydrogen Technology company whose BoostBoxH2 technology has been proven in independent testing to cut fuel costs and significantly reduce diesel emissions, today announced that it has partnered with Ethical Developments, PTE (www.ethicaldevelopments.com.au) with locations in Brisbane and Melbourne, Australia, for the distribution of the BoostBox H2 product line in Australia, New Zealand, The Philippines, South Korea and Israel. This critical announcement also marks the company’s 5th anniversary!
The BoostBoxH2/Ethical Developments announcement comes on the heels of several major milestones for the company including the recent receipt of third party testing and performance verification from federal, state and academic testers, that are to be released shortly to the public.
“Being in a position to introduce Ethical Developments as our partner, with lead customer fleets of over 2,000 vehicles, to distribute our product in multiple countries is exactly where we want to be. These countries demonstrate a strong demand for fuel efficiency and a pressing need for emissions reductions,” said David Rechberger, CEO of BoostBoxH2. “And now we have validation from three independent sources of our fuel saving and emissions cutting claims. Together, the two will be a game changer for BoostBoxH2. Our technology will produce tremendous impacts not only for the over-the road-transportation market, but in stationary power, construction, marine and all other diesel engine applications.”
The BoostBoxH2 technology has been making a substantial impact with users since entering the marketplace. With an average fuel savings of 10% and an average reduction of 70% of NOx and PM emissions, no other technology readily available today can boast such results. The company estimates the Return On Investment (ROI) of the BoostBoxH2 to be between 12-16 months or sooner.
Founded in 2014, BoostBoxH2 is a clean energy technology company based in Boulder, CO. Our leading edge solutions provide unmatched performance and efficiency gains in the operation of diesel engines. Owners and operators of diesel engines are under increased pressure to improve fuel efficiency and reduce emissions. Existing solutions for lowering emissions typically consist of post combustion filtration systems. While those options do reduce emissions, they also decrease fuel efficiency, increase system wear, and significantly increase maintenance costs. Additionally, there are often large down-times for filter system maintenance. BoostBoxH2 solves these problems by providing a fuel cell based hydrogen-on-demand solution for the various diesel engine industries. BoostBoxH2 clean technology adds a minute amount of hydrogen into the air intake of diesel engines. This hydrogen is used to more efficiently ignite and burn the available diesel fuel faster, creating a more complete consumption of the fuel. The result is reduced emissions of greenhouse gases and particulates while simultaneously improving fuel efficiency and torque.
To view the “How It Works” video on the BoostBoxH2 technology, visit the BoostBoxH2 web site at www.boostboxh2.com.
About Ethical Developments, PTE:
Ethical Developments believes hydrogen, as an alternative to fossil fuels, will make a significant contribution to reducing greenhouse gases now, and well into the future. The transport sector (cars, trucks, public transport, domestic flights and shipping) is Australia’s second largest source of greenhouse gas pollution. According to the Climate Council of Australia, the transport sector emitted 102 million tons of carbon dioxide (Mt C02) in 2018, representing 18% of Australia’s annual greenhouse gas pollution. Ethical Developments will deliver highly cost competitive production, storage and refueling options for the Australian and Asian markets, and by partnering with BoostBoxH2, we make a large step in this direction.
For all inquiries about BoostBoxH2, for more visuals and to speak with company officials, please contact Shep Doniger at BDCG at 561-637-5750 or [email protected].


News Release: November 3, 2015
Colley Avenue in Norfolk, Virginia, Selected as the 'People's Choice' Great Place
The American Planning Association announces the "People's Choice" Great Places in America Designation.
CHICAGO — The American Planning Association (APA) announced that Colley Avenue in Norfolk, Virginia, has earned the "People's Choice" designation as one of the Great Places in America in 2015.
For the second year in the row, APA asked the public to nominate their favorite public space, neighborhood, or street. Suggestions were collected throughout October via social media outlets using the hashtag #GreatPlaces. Five finalists were then selected out of the nearly hundred suggestions that were received. The public could then vote for their favorite through APA's website during the second part of October.
"Norfolk is a vibrant, historic port city, filled with authentic, diverse neighborhoods and Colley Avenue in Ghent is just one the many gems our city has to offer," said Norfolk Mayor Paul Fraim. "We are honored to have won this recognition, and excited to be able to share this special and unique place."
Colley Avenue was the clear favorite for this year's "People's Choice" designation. The other finalists up for consideration included Downtown Florence, Alabama; Gallivan Center, Salt Lake City, Utah; South Bend Farmer's Market, South Bend, Indiana; and Union Square, Somerville, Massachusetts.
In October during National Community Planning Month, APA's Great Places in America program names 15 exemplary streets, neighborhoods and public spaces that add value to communities and foster economic growth and jobs. APA's Great Streets, Great Neighborhoods and Great Public Spaces feature unique and authentic characteristics that have evolved from years of thoughtful and deliberate planning by residents, community leaders and planners.
Since Great Places in America was launched in 2007, APA has designated 245 neighborhoods, streets and public spaces. Places are announced annually and represent the gold standard in terms of having a true sense of place, cultural and historical interest, community involvement, and a vision for tomorrow.
About Colley Avenue
Stretching for 18 blocks through the core of Norfolk, Virginia's historic Ghent neighborhood, Colley Avenue forms the spine of a classic 19th century grid-pattern street network. The avenue connects residential blocks lined with a mix of stately historic homes, apartments, and townhouses that blend with restaurants, retail, office, and institutional uses. The avenue's streetscape showcases a blend of architecture ranging from the styles of the 1890s to the modern. The Art Deco facade of the NARO Theater coexists with the modern brick and glass of the Eastern Virginia Medical School Jones Institute.
Dotted throughout its length with generously landscaped stoops, balconies, and outdoor dining, Colley Avenue presents a welcoming pedestrian experience for everyone. The wide sidewalks of its commercial core host activity day and night as outdoor diners mingle with theater patrons and buskers who serenade them all.
2015 Great Neighborhoods
- Crossroads Arts District, Kansas City, Missouri
- Downtown Plano, Plano, Texas
- Roosevelt Row, Phoenix, Arizona
- Wynwood, Miami, Florida
2015 Great Public Spaces
- Balboa Park, San Diego, California
- Flint Farmers' Market, Flint, Michigan
- Hermann Park, Houston, Texas
- Millennium Park, Chicago, Illinois
- Pearl Street Mall, Boulder, Colorado
- Santa Fe Railyard, Santa Fe, New Mexico
2015 Great Streets
- Third Street, McMinnville, Oregon
- Fifth Street, Dayton, Ohio
- Laura Street, Jacksonville, Florida
- Lexington Avenue, Asheville, North Carolina
- Olvera Street, Los Angeles, California
For more information about APA's Great Places in America Program for 2015, and previous years, visit www.planning.org/greatplaces.
For more about National Community Planning Month, visit www.planning.org/ncpm.
The American Planning Association is an independent, not-for-profit educational organization that provides leadership in the development of vital communities. APA and its professional institute, the American Institute of Certified Planners, are dedicated to advancing the art, science and profession of good planning — physical, economic, and social — so as to create communities that offer better choices for where and how people work and live. APA has offices in Washington, D.C., and Chicago, with almost 40,000 members worldwide in nearly 100 countries.


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Free TV Switched Off - Please help
Published on 12 June 2019 01:48 PM
The BBC have just announced they plan to means test the free TV licence for over 75s.
This means 3.7 million pensioners will lose out on the free TV licence. Means-testing may sound fair but in reality it means at least 650,000 of our poorest pensioners facing a big new annual bill they simply can’t afford. The BBC’s decision will cause many older people enormous anxiety and distress.
But it’s the Government’s job to look after older people, not the BBC’s. Age UK national will be handing in the petition you signed very soon but in the meantime, we urgently need your help to put as much pressure as possible on the Government.
How will older people be affected?
Removing older people's access to TV would be an unthinkably cruel blow when many are already facing huge challenges.Half of all over 75s are living with a disability, and many rely on their TV for companionship and entertainment.For those who don't have the internet, TV lets them stay up to date with what's happening in the world.Nearly a third of over 75s are living in poverty or just above the poverty line. Paying a hefty extra bill would simply be impossible when they're barely scraping by as it is.
What can we do?
Together, we must demand the government takes back responsibility for keeping TV free for the oldest people in our society.
Please write to your MP and demand the Government takes back responsibility
Because it’s not just a licence. It’s a lifeline.
Please click the button below, to visit the Age UK national website page and create an email to your MP
You've probablly noticed the huge amount of media coverage Age UK National's campaign has had. It's been on 12 front pages, been on every news channel and The Sun, The Mail, The Express and The Mirror are backing the campaign. Age UK National had an enormous 575,000 signatures to the petition.
If we keep up the pressure we can get our next Prime Minister to save free TV for over 75s but we need to act quickly.
Could you write to Jeremy Hunt and Boris Johnson to ask them to commit to funding the concession?
Just click on the buttons below to visit the action page to make your feelings felt.
A personal appeal by a care worker:
One of our EveryDay Care assistants (Charmain McCabe) was so moved by the thought of TV being taken away from those she cares for that she wrote this totally unprompted appeal:
"I am currently a Personal Care Assistant for EveryDay Care, the social enterprise wholly owned by the charity Age UK North Tyneside, and I first hand see the conditions that people live in, and the budget that they have. Many of the people I support have no family, friends or way of even getting out and about. Sometimes they are living in accommodation that isn’t acceptable for their needs, with minimal support, and for us there is nothing we can do but provide the best care we can while we are there.
Loneliness is a killer and these people have helped shape our country; to help fight wars, fight for independence, fight for women’s rights, worker’s rights and over-all human rights.
They have voted for your government to take care of them like they have for all of us, and in return they are not even entitled to a tiny bit of gratitude.
Convicted criminals get to watch T.V., earn money and benefits for committing crimes to innocent people but, what about the innocent pensioners who have helped shape the world where we live get nothing?
Are you accounting for the money they spend on Care-call, home care, social interaction at a St. John’s ambulance or a wellbeing centre, the only interaction they may have all week or month?
We spend our lives working and paying taxes and fighting for our country, to be forgotten about when we reach a certain age, and are considered no use to some people.
Well I can tell you first-hand, these people are more use than most of us will ever be. There is so much to learn if you listen. It is a pleasure and a privilege to say I care for these people.
I value every day I get to spend with them listening to their wisdom and making a difference. I wish you would look beyond profit and see into lives of people you could be affecting. Please help save T.V. licences."

domain: sociology


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Creole Gets Creative At Restaurant R’evolution
All restaurants promise customers a culinary adventure but only Restaurant R’evolution in New Orleans delivers a journey through both time and taste. Located inside the iconic Royal Sonesta hotel, this fine-dining powerhouse deals out sinfully delicious takes on some of the Big Easy’s favorite foods. And while some chefs can take experimentation a step too far, R’evolution has found the perfect way to blend creativity with the classics.
For you to fully appreciate their unyielding devotion to an immersive dining experience and reinventing Louisiana staples like gumbo, beignets, and po-boys, a brief history lesson is in order. When the citizens of seven nations (Native Americans, French, Spanish, Germans, English, Africans and Italians) all found themselves living in the same area, everyone’s favorite southern city, New Orleans, came to be. Naturally, their cuisines and cultures started to blend together with experimentation taking root and forming what we now have come to know as Cajun or Creole food. It’s the best of all worlds and unique unto itself. Chef’s John Folse and Rick Tramonto have made it their mission to respect the past while presenting a new and revolutionary style of Louisiana food to contemporary diners…and their mission has been accomplished. The food is an enchanting blend of flavors and even the design of R’evolution gives a gracious nod to the past that has brought us to the present.
Diners can enjoy their meals in one of five rooms ranging from the Bienville Room (designed to emulate sitting on a southern front porch and watching the world go by), to the Storyville Parlor (which tells the tale of the seven nations via beautiful hand-painted murals), to The Market Room (which is based on the iconic Solari’s Meat Market). Diners will also find a cozy bar, the wine room and a courtyard room. All the dining spaces at R’evolution have their own unique atmospheres and can be closed off for private parties.
I was lucky enough to have dinner at a table that was in the Bienville room but looked into the Market Room so I could watch the flurry of activity in and around the kitchen. And they take the kitchen very seriously. Not only do they cure and dry-age their own salumi in-house with up to 19 meats curing at a time, but R’evolution even has their Iberico ham raised to their own specifications. That means they control what that little piggy was fed before it went to market, ensuring perfection every time. Salumi is just the beginning when it comes to an almost OCD level of attention to detail at R’evolution (and I say that with the upmost admiration). All the ranges and cooktops in the kitchen are Viking brand. It’s also a silent kitchen, meaning the chefs use walkie-talkies to communicate from various stations so they are able to focus on their work without the chaos of your typical back-of-house. All glassware and decanters in the restaurant are Ridel, so you’re enjoying your wine out of some of the finest glassware available. Speaking of wine, every bottle from their 15,000 bottle cellar is opened and sampled before being served to guests to ensure its freshness and quality. I’m not sure whose job that is but I’m jealous. Something else unique about R’evolution—on top of everything else—is the ability to rent the Chef’s office, complete with an amazing wooden puzzle table that expands to seat private parties of up to 12.
Now, I have to back it up for a second before we dive into the dishes and talk about the glue that holds this whole thing together. The staff. Let me tell you, the passion that flows out of this place is absolutely contagious. From the host, to my amazing and genuine team of Travis, Kendal and Rory, I felt amongst family the entire time. Professional and courteous, they are also fun and personable, enhancing an already fantastic meal. Travis in particular was incredibly informative and kind, always ready to impress with the next course and it was very clear that he takes immense pride in his job.
SO WHAT SHOULD YOU TRY?
A signature, not-to-miss dish is undoubtedly the Fried Crab Beignets. Made with creole cream cheese, marscapone cheese, fresh crab and served with coleslaw and a white and red pepper remoulade, these little bites are a blast of flavor. Another must-have is the infamous and aforementioned salumi. The soppressata and calabrese were my particular favorites but it’s hard to say when you have everything from their award-winning hogshead cheese to bacon-wrapped country pate, all of it made in house. Add to that 4 accoutrements like sauerkraut, red onions, mustard and apricot mostarda and you can create an intense variety of flavor combinations.
Libations are a must and our recommendation for the cocktail lovers is The Saint-sation. It’s their less-sugary take on a cosmopolitan, inspired by the New Orleans Saints cheerleaders who spent an evening dining here. For wine lovers, Rory was an absolute perfectionist when it came to what wine to serve with which course, in this case the Syrah Rose ‘Sybel’ below. But with a cellar of 15,00 bottles, Rory will always be there to help you pick a winner based on your tastes.
With so many unique menu items, it can be a challenge to narrow it down so I’ll do my best to help and whittle it down to my top 3. I can’t put them in any particular order because they were all amazing and for different reasons.
1. Death By Gumbo
Gumbo lovers, rejoice. This dish won “Best Gumbo” in the city in 2012 and 2013, a pretty big accolade for a city where the dish was invented. And the best part? Those were the only two years they won because those were the only two years they entered. This bowl of magic begins with a quail stuffed with andouille sausage, rice and oysters, which is then smothered table-side in a smoky, salty broth. It really is to die for.
Recommended Wine Pairing: Westwood Pinot Noir
2. Sheep Ricotta Gnocchi with Lobster
This dish is also something special, I truly have never had anything like it in my entire life. The gnocchi in this dish are made from sheep’s milk ricotta instead of the usual potato and there are distinct notes of lemon and vanilla. My main man, Travis, nailed it when he excitedly exclaimed, ‘doesn’t it taste like wedding cake??!’. Yes, yes it does. Delicious, creamy, wedding cake. Mixed with giant chunks of lobster. You may not think the two sound like they go well together but I must say this was the most delightfully unexpected dish of the night. My mind couldn’t comprehend the combination of those flavors but…it just WORKED. I highly recommend this to the adventurous diners who are looking for something truly outside the norm.
Recommended Wine Pairing: Craggy Range Sauvignon Blanc
3. Seared Sea Scallops and Foie Gras
This is one decadent dish. Scallops served with bacon vinaigrette, white bean puree, black truffle shavings and topped with seared Hudson Valley foie gras. Rich, buttery, and heavenly, this is the dish for seafood lovers!
Recommended Wine Pairing: Macon Villages White Burgundy
Creole Cream Cheese Bread Pudding Crème Brûlée
It sounds like a mouthful, right? Well, it is. This delicious little finisher packs the right punch to end your meal. But, R’evolution isn’t done yet. At the end of every meal, diners are presented with The Mignardise, which mean’s ‘small treat’. It’s a fantastic box, reminiscent of a jewelry box, where each drawers contains a little something extra to surprise and delight. The contents change on the whim of the Chef but you can expect anything from prosecco truffles to pralines with applewood smoked bacon. If you aren’t bursting with happiness by this point, you might need to see your doctor.
Eating at Restaurant R’evolution is no small treat, in fact it is a great honor. The quality of service and the attention to detail are as impressive as the food and I would never hesitate to point diners looking for a special culinary experience in their direction. I look forward to my next visit and until then, you will find me dreaming of fried crab beignets and treat-filled boxes.
For more information or for reservations, call (504) 553-2277 or visit www.revolutionnola.com

domain: food


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Magimix food processors
MAGIMIX FOOD PROCESSORS
Invented by Magimix and still manufactured in France, the multifunction food processor has become the single most important kitchen machine for everyday cooking and special gourmet occasions.
Performing the functions of up to 8 other kitchen machines, the Magimix Food Processor is the most versatile and invaluable addition to any kitchen.
Ideal for slicing, grating, chopping, whisking, blending and baking.
All it takes is three buttons (stop/auto/pulse) to use all the different functions.
The motor automatically adjusts the power depending on what’s in the mixing bowl.
100 Recipe Cookbook provides you with mouth-watering ideas for everything from
Celebration Cakes to 3-Course Dinners.
All accessories are dishwasher safe.
Accessory box for compact and safe storage.
3 bowls allow you to effortlessly carry out several tasks in quick succession.
Main Bowl: ideal for all preparations of large quantity
Midi Bowl: ideal for all types of slicing & grating
Mini Bowl: with specific mini blade for small quantities
Manufactured in France.
Powerful and efficient, ultra-quiet induction motor with a reassuring 30 year guarantee.


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Bang!! Beng!! Bing!! Bong!! Bung!!
Bungers: David Bath, Christopher Hood, Rebecca Mann, Lea Docks, Rodney Jackson… could possibly squeeze one more in.
Special Guest: TBA
Bang!! Beng!! Bing!! Bong!! Bung!! is an opportunity for less experienced musical performers to have a play on a good stage with a friendly audience. The format is five or six ‘Bungers’ as we call them playing five songs each (max. 20 minutes), followed by a set from a more experienced performer. Original songs are preferred but not obiligatory.


ACPA Special Bulletin: 2017 IPPS Proposed Rule
Summary of Important Proposals in CMS 1655-P
Medicare Outpatient Observation Notice (MOON)
On August 6, 2015, the NOTICE Act became law, requiring hospitals and critical access hospitals to provide written notification and oral explanation of such notification to individuals receiving observation services as an outpatient for more than 24 hours. This must be accomplished no later than 36 hours after the initiation of observation services (or upon release, if sooner than 36 hours). The effective date of this law is 12 months from NOTICE enactment, or August 6, 2016. CMS further proposes that the notice must be given before discharge, transfer, or admission if these events occur prior to 36 hours after initiation of observation services.
The NOTICE Act requires hospitals to explain the status of outpatients receiving observation services, as well as the implications of such status, including cost-sharing requirements and SNF eligibility. NOTICE further requires the notification to be written and formatted using plain language. The written notification must be signed either by the patient or the person acting on the patient's behalf, or in case of refusal, by the staff member of the hospital who presented the written notification. In the case of such refusal, the name and title of the staff member, a certification that the notification was presented, and the date and time the notification was presented must be recorded on the notification.
CMS created the Medicare Outpatient Observation Notice (MOON) to help hospitals satisfy this requirement. CMS deems the MOON applicable to any patient who receives benefits under Title XVIII of the Social Security Act, which includes Medicare Part A patients (with or without Part B coverage) and Medicare Part C (Medicare Advantage) patients. Physician advisors should be aware that observation is a service provided to outpatients upon the order of an eligible provider. Not all outpatients in the hospital are receiving observation services, and these patients (such as outpatient surgical patients) would not require a MOON even if outpatient services extend beyond 24 hours. Similarly, observation patients receiving less than 24 hours of observation services will not require a MOON.
The draft MOON, available here, is still awaiting final approval by the Office for Management and Budget (OMB). In general, it appears to be a well-written document that accurately reflects Medicare policy. One shortcoming of the draft MOON is that it does not inform the beneficiary that there are no appeal rights associated with the decision to provide observation services under outpatient status (as opposed to inpatient admission). Though CMS proposes to amend 42 CFR 405.926 (a list on non-appealable actions) so that the MOON does not trigger appeal rights, it includes no such notice in the document delivered to beneficiaries.
Delivery of the MOON to Medicare Advantage (MA) patients seems to make little sense due to different cost-sharing and SNF eligibility rules that are plan specific - but is required because the NOTICE Act that amended Title XVIII does not exclude MA patients. Keep in mind that patients who receive observation for more than 24 hours, followed by a decision for inpatient admission, are proposed to need a MOON prior to 36 hours after the start of observation, or prior to inpatient admission - whichever is sooner. In addition, since a significant portion of observation patients are released at just over 24 hours, it may prove operationally impossible to deliver the MOON after 24 hours of observation but prior to release. Hospitals may be wise to give the MOON to every observation patient regardless of time in observation.
Acute Care Hospital Market Basket Adjustments
2 Midnight -0.2% Payment Adjustment
It is important to note that the 2 Midnight Rule is not changing with this proposed rule, as reported in some outlets. All that is being proposed for retraction is a payment adjustment that accompanied the 2 Midnight Rule.
CMS is proposing to remove the 0.2% reduction in Inpatient Prospective Payment System (IPPS) payments that was instituted in FY 2014 when the 2 Midnight Rule went into effect. This reduction was the result of assumptions made by CMS in 2013 that the 2 Midnight Rule would increase the net number of inpatient admissions. These assumptions were later challenged in the Shands Jacksonville Medical Center v Burwell case; the judge remanded the case back to CMS to respond to the judge's inquiries. The IPPS rule contains CMS' response. Upon considering FY 2014 and FY 2015 actuarial data and the active litigation, CMS proposes to remove the 0.2% market basket reduction made in FY 2014 and subsequent years. For FY 2017 onward, a factor of 1/0.998 is proposed to be multiplied into the IPPS rates to offset the 0.998 factor implemented in FY 2014. Furthermore, CMS proposes to make up the difference from FYs 2014, 2015, and 2016 by including a one-time factor of 1.006 in the 2017 IPPS rates, which will be nullified in 2018 by a factor of 1/1.006.
CMS had predicted a net of 40,000 more inpatient admissions and net increased expenditure of $220M as a result of the 2 Midnight Rule. What actually happened? CMS actuaries released this analysis in February 2016.
Read the full article here


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Pom Amsterdam was founded by sisters Liesbeth and Violet Lotgering, who make their own high quality clothing and accessories. Their collections are elegant and feminine but with use of powerful contrasting colours, with pronounced prints. Their unique prints tell a story and are all hand-printed by Violet in their Amsterdam studio.
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domain: artistic


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The COVID-19 pandemic has exposed deep inequities in our society. Women, especially women of color, are negatively and disproportionately impacted. According to a health study, 70 percent of women ages 18-29 and 55 percent of women of all ages have reported mental health challenges due to pandemic-related worry or stress. The lack of access to quality healthcare, economic security, childcare and other family support services are major barriers many women are facing today.
We can change this by raising our voices . Join our W Challenge community and expand our representation.
More Details on 2021 W Challenge Coming Soon! RSVP to join the 2021 Women Equality Day Celebration here.
Check out our 2020 activities below
Women’s Equality Day Virtual Celebration
To celebrate Women’s Equality Day on August 26, 2020, then San Francisco Assessor Carmen Chu had an in-depth conversation with Mayor London Breed to discuss how their personal experiences as women of color guided their decision making and leadership styles, as well as their commitments to promoting voting rights, racial equity and civic engagement.
If you missed it, check out our video below:
W Challenge Campaign to Highlight 100 Women Leaders
In honor of the 100 anniversary of the ratification of the 19th Amendment, the 2020 W Challenge led a 10-week social media campaign to spotlight the 100 years of women leaders. Read about them here and continue to celebration their contriubutions. Join our W Challenge network of partner organizations here to receive more details!
Ask Others to Join You for the #WChallenge
#WChallenge Kick Off in 2018
Tag #WChallenge to be a featured supporter!


KOYO Bearing NKJ60/25 design bearings have two stamped window-type steel cages, an inner ring without flanges and a guide ring centred on the inner ring. The CC design is indicated by the designation suffix C or CC. Large CC design bearings with the designation suffix EC or ECC have an optimized internal design for increased load carrying capacity.
KOYO Bearing NKJ60/25 design bearings have two stamped window-type steel cages, an inner ring without flanges and a guide ring centred on the inner ring (d ≤ 65 mm) or on the cages (d >65 mm). They have an annular groove and three lubrication holes in the outer ring. KOYO Bearing NKJ60/25 design bearings are indicated by the designation suffix E. All E design bearings have an optimized internal design for increased load carrying capacity.
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Original KOYO NKJ80/25 bearing; professional service on NKJ80/25KOYO NKJ80/25A | Leader| WHEEL HUB INC BEARING VW Golf Estate TSI 105 MK 6 (2009·) 1|2L – 104 BHP Top Ger AR 4;5 10 22 Timken B1 4|5 mm 10x22x4|5mm Needle roller bearings WHEEL HUB INC BEARING VW Eos Convertible TDI 140 (2011·) 2|0L – 138 BHP Top Germ


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Located in the small, upscale city of Westlake Village, California, which is about 40 miles northwest of downtown Los Angeles, Ludington Institute for Family Enrichment (LIFE) is a comprehensive mental health facility that specializes in the treatment of clients struggling with mental health and emotional disorders. LIFE was established in 1995 by Alan Ludington, MS, MDiv, MFT, who has a background in Christian counseling and addiction treatment. His goal with LIFE is to offer comprehensive, integrated therapeutic services to individuals, couples and families. The facility offers outpatient services including individual and group child, adolescent and family therapy; trauma work; issue-based therapy and couples counseling.
Treatment and Staff
New clients at Ludington Institute for Family Enrichment undergo an extensive assessment that considers emotional, cultural and behavioral factors. LIFE offers clients a comprehensive approach to treatment that integrates evidence-based and holistic methods. Clients with severe mood disorders receive medication management as needed. This helps the staff create an individualized treatment program this is customized to fit the specific needs of the client. Outpatient counseling programs offer a vast array of therapies including evidence-based methods like CBT, DBT and EMDR to treat past trauma. In addition, the facility offers workshops that teach stress management and coping skills.
For individuals and families struggling with addiction, LIFE offers a specialized treatment track staff to treat many forms of addiction, along with the effects on couples and families. As part of this program, there are on-site men’s recovery groups available, as well as referrals to local recovery programs (like AA, NA and Alanon). LIFE also has working relationships with a number of inpatient and outpatient programs that specialize in treating both adult and adolescent chemical dependency issues and can provide recommendations to those who need a higher level of care.
The team of Ludington Institute for Family Enrichment is comprised of Master’s-level therapists, LCSWs, psychologists and consulting psychiatrists.
In addition to outpatient counseling for a range of mental health disorders, Ludington Institute for Family Enrichment also provides family counseling as well as couples counseling and therapy groups.
Ludington Institute for Family Enrichment is a well-established treatment facility that specializes in the care of clients of all ages struggling with addiction and various mental health issues. For clients in the Los Angeles area looking for a comprehensive counseling program that utilizes evidence-based and holistic methods, LIFE is an excellent choice.
Ludington Institute for Family Enrichment
875 South Westlake Blvd, Ste 211
Westlake Village, CA 91361
Ludington Institute for Family Enrichment Cost: Call for cost; insurance accepted. Reach Ludington Institute for Family Enrichment by phone at (805) 449-4375 or by email at [email protected]. Find Ludington Institute for Family Enrichment on Facebook
Do you have a complaint or review of Ludington Institute for Family Enrichment to add? Use the comments area below to add your Ludington Institute for Family Enrichment review.


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domain: design


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Characterisation and modulation of drug resistance in lung cancer cell lines
Dunne, Gráinne (2010) Characterisation and modulation of drug resistance in lung cancer cell lines. Master of Science thesis, Dublin City University.
Full text available as:
Chemotherapy drug resistance is a major obstacle in the treatment of cancer. It can result from an increase in levels of cellular drug efflux pumps such as P-glycoprotein (P-gp). Using cellular models, this thesis aimed to investigate resistance in lung cancer cells while developing siRNA and membrane proteomic techniques and to increase our knowledge of the effect of lapatinib, a newly developed targeted therapy, in these resistant cells.
Lapatinib, a growth factor receptor tyrosine kinase inhibitor synergised with P-gp substrate cytotoxics in P-gp over-expressing resistant cells. However, lapatinib treatment, at clinically relevant concentrations, also increased levels of the P-gp drug transporter in a dose-responsive manner. Conversely, exposure to the epidermal growth factor (EGF), an endogenous growth factor receptor ligand, resulted in a decrease in P-gp expression. Using drug accumulation, efflux and toxicity assays we determined that alteration in P-gp levels by either lapatinib or EGF had little functional significance.
P-gp is not the only resistance mechanism so siRNA-mediated gene silencing was exploited to investigate the role of additional proteins with potential roles in resistance. Firstly, P-gp knockdown by siRNA was coupled with toxicity and accumulation assays to determine the impact of silencing this protein in the chosen resistant lung cells. Additional putative targets were chosen from microarray data identifying genes associated with the development of paclitaxel resistance. Of the three genes investigated, ID3, CRYZ and CRIP1, ID3 emerged as having a potential role in contributing to resistance in one of the resistant lung carcinoma cell lines investigated.
Many of the proteins important in resistance are membrane expressed but due to their size and hydrophobic nature, can be difficult to characterise. A 2D-LC-MS method was designed and employed to examine membrane proteins from the resistant lung cell models. Suitable parameters important in optimal identification of the proteins were determined. Large numbers of proteins were identified and comparisons made, highlighting those that were differentially expressed.
Archive Staff Only: edit this record


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A comprehensive, firsthand overview of the world of computers details the author's introduction to microcomputers, the perils and problems of computer technology, and softwareaquot;Take it back, aquot; I told Dick. aquot;I think I want a DEC VT-100.aquot; aquot;Sure you can have your money back, aquot; he says. aquot;But I have a Televideo at home, and wea#39;ve had that one out there as a demo for a year, and nobody ever had any problems with either of anbsp;...
|Title||:||The users guide to small computers|
|Publisher||:||Pocket Books - 1984-10|

domain: library


Car repair in Fresno is more than simply correcting cars; it’s about maintaining the lifeblood of the city’s transport system. Fresno’s citizens depend on their cars to understand the large expanse of the city, and having a reliable vehicle fix support is essential.
Fresno’s automobile fix shops offer a wide variety of solutions to cater to the diverse wants of its community. From routine maintenance like fat changes and tire rotations to complicated motor diagnostics and transmission fixes, these shops are designed with qualified experts and state-of-the-art equipment. Whether you get a compact vehicle or a heavy-duty vehicle, Fresno’s automobile fix stores are organized to handle it all.
The mechanics in Fresno realize that car breakdowns can be a supply of strain and difficulty, which is why they’re committed to giving rapidly and successful service. Several stores offer same-day or next-day sessions to obtain you back on the way as rapidly as possible. The target would be to decrease the disruption to your daily life.
Affordability is another essential aspect of vehicle restoration in Fresno. Several stores offer competitive rates and translucent quotes, ensuring that you don’t experience any unexpected expenses. They realize that vehicle repairs can sometimes stress your financial allowance, so they assist you to find the many cost-effective solutions.
What sets Fresno’s car repair apart could be the focus on client service. Mechanics take the time to explain the problems with your vehicle, discuss restoration alternatives, and provide tips to keep your car working smoothly. That commitment to transparency develops confidence and long-lasting associations with clients.
Safety is of maximum significance in Fresno, and vehicle restoration stores prioritize the well-being of their customers. Appropriate fixes and maintenance not just increase the life span of your car or truck but in addition increase its safety features, ensuring you and your guests stay protected on the road.
Along with routine auto fix, many stores in Fresno present specific services such as for example air conditioning restoration, brake program preservation, and electric program diagnostics. This detailed method implies that whatsoever problem your car or truck faces, there’s a professional in Fresno who is able to handle it.
Last but most certainly not least, the Fresno car repair Auto Repair Shop Fresno prides itself on being environmentally responsible. They’re alert to the impact of automobile fixes on the surroundings and get steps to get rid of spend precisely and apply eco-friendly practices.
In summary, vehicle fix in Fresno is more than a site; it’s a pillar of support for the city’s residents. Whether you need routine maintenance or complicated repairs, Fresno’s automobile repair stores are specialized in providing top-notch support, ensuring your automobile stays in optimal problem and prepared for the trail ahead.


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Something to make you smile from my beautiful sister Rachel.
Here is a lovely fact for you: Sea Otters have a favourite rock which they will keep with them at all times. You should look up a picture of some sea otters because they are super cute and will make you smile regardless of anything.
She is or course right – Sea Otters truly are wonderful.
So if anything goes down Sea Otters come to our minds 🙂


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I have been fond of quotes since my childhood. Quotes are one of the reasons that I got inspired to write. There is a hidden story behind every quote. A quote simply envelopes a story and its essence within few lines. I enjoy reading them a lot because they are sweet and short yet speak in lengths! As I'm too lazy to read books, quotes capture my interest with their brevity. Quotes are just amazing!!
My quote dedicated to all the 'Quotes' that inspired me :)
A Quote is like a seed that implicitly contains the tree of wisdom, It sprouts in our soul when it is nourished with realization.


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Photograph of Topiary at Green Animals
c. 1972 - 1982
Photograph of the camel topiary figure in the garden at Green Animals, outlined in white. The giraffe figure is also visible in the frame.
Penned inscription on verso reads "Green Animals - Camel"
7.75" X 10"
Taken for the Preservation Society of Newport County, by Hopf Photography
For more information about this item, please contact its owning institution.


Online report of the Progressive Review. For 53 years, the news while there's still time to do something about it.
May 9, 2017
Nearly two thirds of Americans plan to work past retirement age
Gallup -Nearly two in three employed U.S. adults, 63%, say they plan to work past retirement age, but on a part-time basis. An additional 11% say they will work full time once they hit retirement age. A quarter of employed Americans say they will stop working altogether
63% say they will continue to work, but work part time
25% say they will stop working altogether
More Americans say they will retire after, rather than before, age 65