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Francesca Sanna’s The Journey is a children’s book about refugees. After the war takes their father and makes staying where they are impossible, two children and their mother brave the unknown in an effort to find somewhere safe they can live. They cross borders, travel by land, sea, and on foot, never sure if “here” is the right place.
This is a brightly colored and beautifully illustrated tale on a dark and frightening topic. The story is told from the sibling’s point of view, although the clever images show what the words don’t illustrate: a mother who is very much afraid, but who must hide her own fear in order to comfort her children. War is depicted as a gluttonous darkness devouring everything in its path, which cleverly manages to make it frightening without depicting the associated violence.
The book doesn’t have a happy ending, although it could be viewed as hopeful, as the refugees are still looking for a safe place. The book illustrates the struggles faced by refugees the world over as they are forced to flee, but are often turned away and persecuted wherever they go. Francesca Sanna compiled a collection of real life stories of refugees together to make this book; as such, it’s a general telling that can be easily applicable to many, many people.
The Journey is a somewhat bleak children’s book, but one that talks about a topic that is very pressing. The contrasting pictures and words are likely to inspire conversation, asking children and adults alike to discuss the topic of conflict and the plight of refugees the world over. I’d highly recommend the use of this book in an educational setting. Francesca Sanna is an illustrator to keep an eye on.
Whitney Smyth received a Master’s in Book Publishing and Technical Writing at Portland State University, following a Bachelor’s in English at the University of Arizona. She took over ownership of Portland Book Review in December of 2014. She also works as a freelance editor and can be commissioned at Smyth Editorial Services and spends what little free time she has on her own writing. Coming from a family of readers she devours an average of one hundred books a year, in a variety of genres. Her favorite authors are far too numerous to list, but include Alexandre Dumas, Mary Shelley, Jim Butcher, and John Green.
All Barbie lovers out there will learn about Barbie’s famous creator in this short story! Ruth Handler was the creative and artistic inventor of the Barbie doll. Her motive for this invention was her young daughter, Barbara, who had [...]
Aimed at a seven to ten-year old audience, author Candace Fleming’s own three words, “history meets hijinks,” sum up this story quite well. Ben Franklin and his stinky feet (apparently) travel through time to modern day Rolling Hills, [...]
Like other Pig the Pug books, Pig the Elf is full of this larger-than-life dog, both in attitude and life lessons. The big lesson in this book is: do no bite Santa’s rear. Just kidding, while that is a key part of the story, Pig upon the [...]


Beatboxing is a physical and creative art form that allows people of all ages to express themselves, to comment on the world they live in, and to play the roles of creator and creation. As one of the foremost innovators and advocates of this unique musical genre, all Yuri Lane needs is his vocal instrument and trusty harmonica and the possibilities of creating music and narrative are endless. Whether he’s performing one of his groundbreaking and critically acclaimed beatbox plays* (From Tel Aviv to Ramallah; Soundtrack City; MeTube), or drawing from all of them to create an original, audience-driven show, this self-proclaimed “Beatbox Evangelist” never fails to engage listeners as he incorporates them into his exciting symphony of sound.
*Individual show descriptions available upon request
For More Information Call 312-724-7604


HR software is also sometimes known as Human Resources Management Systems (HRMS). Whatever you call it, the widespread adoption of digital HR solutions is showing no signs of slowing down. So, what’s going on?
Today, we’re going to look at some of the convincing explanations behind the business world’s migration to online HR solutions. If your company is still using spreadsheets that lack the capacity to support the nuanced delivery of modern HR processes, keep reading for all the inspiration you need in moving away from outdated HR practices and towards modern software.
For further information, read more on the benefits of cloud based HR software. Otherwise, let’s start our list.
Streamline Routine HR Tasks
One of the central roles in any HR department is the storage of important documents. For example, an HR employee could reasonably expect to handle requests for access to data such as contracts, contractor agreements, and staff records. HR software stores all data in an easily navigable central hub, reducing the administration time required to access various documents.
Research shows that new staff members who undergo a logical and welcoming onboarding process are more likely to value their role. This leads staff to self-monitor their performance to maintain high standards. HR software can reduce paperwork and increase face-time during the onboarding process, increasing the likelihood of a positive experience.
Simplified Employee Management
HR management software can help HR staff to succeed in helping employees to develop skill sets and strive toward career advancement within the company. The software does this by creating individual profiles for each staff member, with the aim of noting and tracking educational goals.
To that end, HR software can assist companies in providing staff with access to relevant seminars, training courses, and other beneficial educational resources.
Employee management also means analysing absenteeism and tardiness. Flagged issues could reveal commuting issues that affect morale and productivity. Understanding where allowances can be made that raise output to expected levels can mitigate problems with workflow.
Tracking & Meeting Business Goals (KPIs)
A Key Performance Indicator (KPI) could be any metric that the company has highlighted as a notifier of progression toward a goal. HR software can present data that highlights where staff issues may be contributing toward a lag in achieving KPIs on time.
Payroll tracking is another task that dedicated software can process. Where payroll is completed correctly and on time each week/month, staff retention rates will benefit.
Conclusion – Spreadsheets vs HR Software
HR software offers a cost-effective central store of information that expedites HR tasks and delivers higher levels of data security. The software can also help to provide guidance and prompts to keep all company processes in line with GDPR considerations.
From startups with fewer than 10 members of staff to much larger national and international enterprises, replacing spreadsheets with powerful HR software will only serve to benefit the company in setting, tracking, and achieving goals. Staff will also benefit from a tracked performance and greater access to rewarding educational opportunities.


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Hello to all choizles! I’m Vera and no, Pootee is not my surname, nor my middle name. It’s just a nickname that sounds similar to my middle name ‘Putri’ to those who can’t pronounce ‘r’ properly. Haha, okay enough of the crap. So yeah, I’m Indonesian, however I grew up in Singapore, and am now studying in Melbourne!
It’s been a great and pleasant experience each time I go for David Choi’s concert. And I am amazed at how his music can make me feel so calm, and carefree. I look up to David Choi cos he treats his fans as friends and regardless of his high status, he’s still such a down-to-earth and humble person! Thanks for creating awesome music for all of us David! We look forward to see you again in the near future, and hear more of your music <3
PS. I do hope you still remember me though I went missing in action for the past months..

domain: artistic


Automobile Battery Thermal Management System Global Market Insights 2022
An advanced battery thermal management system for emerging electric vehicles is investigated experimentally. The battery thermal management system developed is a hybrid of thermoelectric cooling, forced air cooling, and liquid cooling. The liquid coolant makes indirect contact with the battery and serves as a medium for removing heat generated by the battery during operation. Forced air-assisted heat removal is carried out from the thermoelectric liquid casing’s condenser side. Extensive tests are performed on a simulated electric vehicle battery system. The results of the experiments show a promising cooling effect with a reasonable amount of power dissipation. Electric vehicles (EVs) are widely publicized as a greener and more cost-effective alternative to conventional vehicles.
For competitor segment, the report include global key players of Automobile Battery Thermal Management System as well as some small players. The information for each competitor include:
Main Business Information
Production Capacity, Poduction Volume, Revenue, Price and Gross Margin


Neocrisis – We had the chance to get a interview about Perang Laut – Maritime Warfare. It is currently a work in process and is expected to be released on PC.
Bandai Namco has released the teaser trailer for its recently announced Super Dragon Ball Heroes: World Mission for Switch. The game will feature card-based battles with a maximum of seven cards per player. Approximately 1,160 cards from the Super Dragon Ball Heroes arcade games are included, as well as about 350 characters. Source link
Agony opens up with a dark blood-filled world full of sadistic themes and demonic creatures. Attempting to convince the player that this horror game is something that can rival some of the most gruesome and terrifying titles within the genre until you experience all the vexing moments that follow. That sense of uncomfortable tension quickly […]
— Xbox Enthusiast: A lot of announcements were made throughout E3 2018, but one of the primary takeaways happened at the very end of Microsoft’s show. Head of Xbox Phil Spencer announced, rather casually, that Microsoft’s hardware teams are currently “deep in development of the next Xbox systems”. Notice that phrasing—”systems”. That’s plural. It does […]


I am writing this whilst watching the draw for the Euro 2012 qualifying groups – who says boys can’t multi-task? The quality of customer service in France has been something I have discussed with a number of people since being here. A friend from my cricket team ran a restaurant in Strasbourg and was very unhappy with the attitude of the people who worked in the restaurant – is it unusual for a restaurant owner to have a poor view of the people working there? Well it fits in with my some of my experience and that of others I have talked to. It has always been something of a relief to say, well at least its not as bad as that in Paris, as the attitude there to people not from Paris is so snooty. (For those interested England’s group for the Euro 2012 qualifiers is Switzerland, Bulgaria, Wales and Montenegro.) In further parenthesis it was interesting to read a piece about service in France but I was disappointed that the sub-editors who had headlined the piece had put that it was about service in France whilst, as is normal, it was about Paris. I was surprised that the piece put the attitude of people down to the revolution and a keen sense that everyone is equal to you and no-one superior, I’m not convinced, particularly as it is not so strongly the case outside Paris as in Paris.
Today I will be watching for the result of the presidential election in Ukraine where little seems to have changed since I was there for the election in 2004 and I will be surprised if the result is anything other than close with the two halves of the country split. Also starting today, as far as people here are concerned, is the Six Nations. With England defeating Wales and Ireland beating Italy yesterday. Alsace is supposed to be a football area, it doesn’t have any top-flight rugby teams and, even with the problems of the football le Racing they are still several divisions above the rugby team of the same name – who are though unbeaten in their last 10 games. But people I’ve worked with this week have talked about looking forward to the start of the 6 Nations, so much so that it has surprised me. My memories of the 5 Nations from my youth include the match at Twickenham between England and France when someone would always release a cock onto the pitch. I always wondered about the wisdom of having it as a symbol even before I was old enough to understand other meanings for the word. Yesterday, on my way to see a disappointing exhibition of drawings by an architect whilst he travelled on the trams of Strasbourg, I came across this building:
the home of DNA, the media group which produce the main local paper. A close-up of the clock shows:


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Knowing can be a curse on a person’s life. I’d traded in a pack of lies for a...– Sue Monk Kidd, The Secret Life of Bees (via creatingaquietmind)
We are dying from overthinking. We are slowly killing ourselves by thinking...– Anthony Hopkins (via asauros)
i didnt do any wrong today, but u make it sound like i all in the wrong today ..
Look at you. You’re young. And you’re scared. Why are you so scared? Stop being...– Louise Flory (via m-wol)
so close yet so distant..
how can i even say a word to you, how could i start a new conversation after so much have happen? see you so close with the rest, even sitting beside you, there wasnt any conversation to begin with. how disappointing to be after that one night of so much happiness even if its a dream just for me? only i could just dream of those happy moments, while some just is able to make use of the moment of...
When you meet someone who gets your sense of humor... →
99 MORE Life Hacks to make your life easier!
shialabeowulf: (My original 99 Life Hacks post) Read More

domain: psychology


The proliferation of sensors and cameras fosters next-generation ecosystems such as smart cities, smart transportation, smart infrastructure, etc. The value lies in accurately translating visual data into actionable insights in real-time. The customer wanted to automate the labeling process for street videos with live footage from various daytime conditions and locations to identify objects such as vehicles, street lights, and pedestrians.
Manually labeling objects from street videos was leading to:
Apexon brought onboard its Image & Video Analytics platform, a proprietary deep learning platform, that speeds up analysis of visual data to enable:
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Automation of a Seamless Integration of Dealer Track for Credit Application Submission Process Consolidation for a Leading Financial Services Provider
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Phu Mai Anh Co. Ltd, established in 2005 (formerly Duy Viet Chemical Co. Ltd.), is a leading distributor of food ingredients and feed additives in Vietnam. PMA Co. Ltd also specializes in innovative ingredients for pharma- and other industries. We have more than 20-year experience in the industry with talented human resources, modern facilities, and an intensive understanding of the market. We offer a wide range of high-quality products from top-ranked suppliers globally in American (US, Peru, Columbia), Europe (France, Germany, Czech Republic, Spain), Asian (India, China, Malaysia, Singapore, Indonesia, Taiwan, Japan, South Korea), Oceanian (Australia and New Zealand) continents, and more. We are proud to be a trusted partner for many key clients in Vietnam, whose products and services are well-recognized in Vietnam for many years.
Since then, we have built up a reputation as a reliable supplier of high-quality food ingredients and feed additives for professional and industrial producers in Vietnam.
PMA people have dedicated themselves mostly to satisfy everyday needs of the industry. Together with our suppliers, we are happy to provide the best quality products to the market and maximize our client's profits. In collaboration with professional experts and scientists around the globe, we have been investigating new advanced products and services for our customers. We have also developed new formulations of additives in both the feed and food industries to address all challenges that local farmers are encountering. For sustainable development, we are interested in looking for phytogenic additives, as potential alternatives for artificial compounds, to build up a healthy life for both humans and livestock.

domain: chemistry


text:
Research Article - Biomedical Research (2017) Volume 28, Issue 13
The risk factors of intracranial aneurysm rupture and the assessing efficacy of CTA
3Medical Imaging Centre, 2nd Affiliated Hospital of Harbin Medical University, Harbin, PR China
- *Corresponding Author:
- Jia-Wei Tian
Medical Imaging Centre
Second Affiliated Hospital of Harbin Medical University, PR China
Accepted on May 22, 2017
Objective: The objective is to apply the Computed Tomographic Angiography (CTA) on assessing the risk factors of intracranial aneurysm rupture, providing the reference for the prevention of intracranial aneurysm rupture.
Methods: 252 intracranial aneurysm rupture patients admitted in our hospital between February 2014- February 2017 were selected for prospective study. The rate of intracranial aneurysm rupture was evaluated and calculated. The univariate analysis was used to evaluate the different clinical characteristics and CTA results of patients with intracranial aneurysm rupture patients, and then the factors with statistical difference were included in Logistic multivariate regression analysis to analyse the risk factors of intracranial aneurysm rupture.
Results: In 252 patients, 45 patients were confirmed as intracranial aneurysm rupture during the surgery, the rate of intracranial aneurysm rupture was 17.86%. Logistic multivariate regression analysis results showed that complicating with hypertension, the diameter of aneurysm ≥ 3.850 mm, the ratio of aneurysm depth to aneurysm neck width (aspect ratio, AR) ≥ 1.448, the ratio of tumor depth to patent artery diameter (size ratio, SR) ≥ 1.388, the ratio of aneurysm area to the patent artery area at aneurysm neck ≥ 1.192, irregular aneurysm wall and the aneurysm locating at posterior communicating artery, internal carotid artery or middle cerebral artery were the independent risk factors of intracranial aneurysm rupture. The age ≥ 60, male patient and complicating with diabetes were the protective factors (P<0.05).
Conclusion: Intracranial aneurysm rupture is closely related to clinical characteristics, aneurysm morphology and location. Based on the baseline characteristics, aneurysm diameter, AR, SR and area ratio in CTA image could be the reliable references of intracranial aneurysm rupture risk.
Intracranial aneurysm, Rupture, Risk factor, CT angiography, Evaluation.
Intracranial aneurysm is an acute cerebrovascular disease caused by cystic encephalocele of intracranial arterial wall in Neurosurgery Department [1,2]. It is also the premonitory symptom of subarachnoid hemorrhage, the disability rate and mortality of which are high. Hemorrhage caused by intracranial aneurysm rupture is the main reason of subarachnoid hemorrhage. Therefore, combining with the rapid diagnosis and treatment, accurately assessing the risk of aneurysm rupture and intervening timely is critical for improving the survival rate and prognosis of patients [3-5]. As a simple and non-invasive method, Computed Tomographic Angiography (CTA) is widely applied in the assessment of intracranial aneurysm size, structure and anatomical location.
Some researchers also have proposed that the advantage of CTA is hopeful to provide the reference for intracranial aneurysm rupture [6-8]. In this study, 252 intracranial aneurysm rupture patients were included and CTA was applied to assess the risk factors of aneurysm rupture.
Materials and Methods
252 intracranial aneurysm patients admitted in our hospital during February, 2014-February 2017 were selected as objects for the prospective study. Inclusion criteria: intracranial aneurysm was confirmed by medical imaging and surgery, and there were no criteria of intracranial aneurysm rupture when included; the clinical data were complete; the patients were informed about this study and accepted CTA voluntarily. Exclusion criteria: the patients were complicated with other hemorrhagic disease or vascular diseases such as hypertensive intracerebral hematoma, arteriovenous fistula, moyamoya disease, facial hemangioma and head trauma; infection or intracranial aneurysm caused by trauma; unconsciousness or unable to cooperate; the patients received vessel clamp or endovascular interventional therapy before inclusion; contrast agent allergy. The age of 252 patients was 24-79 y and the average age was (51.52 ± 11.38 y). There were 167 male patients and 85 female patients. The complications: 161 patients had hypertension, 78 patients had diabetes and 85 patients had hyperlipemia. The Ethics Committee of our hospital approved this study.
The baseline of patient characteristics: The baselines of patient characteristics were collected, including age, gender, past medical history, family history and personal history. The past medical history included hypertension, diabetes, hyperlipemia, coronary heart disease and polycystic kidney et al, the family history included intracranial aneurysm, subarachnoid hemorrhage, and the personal history included smoking and drinking history.
CTA: The patients in both groups received CTA on the day admitted; the equipment used for the examination was LightSpeed 64 slice CT scanner (GE Healthcare, California, USA). Scanning parameters: the diameter was 64 mm × 0.5 mm, the pitch was 0.641, reconstructed slice thickness was 0.5 mm, the interval was 0.3 mm, the bulb rotation time was 0.5 s/ circle, the matrix was 512 × 512; scanning range: from calvarium to the lower edge of atlas; 60-80 ml non-ionic contrast agent iohexol and 100 ml normal saline were injected through cubital vein with speed of 4 ml/s, the threshold was set as 100 Hu at aortic arch. After scanning, the three dimensional image was reconstructed by several methods including multiplane reconstruction, maximal intensity projection and volume rendering technique, ADW 4.5 workstation was applied for image post-processing. In addition to aneurysm location and aneurysm wall, the aneurysm parameters were also assessed including aneurysm depth (Hmax, the maximal distance from the midpoint of aneurysm neck to aneurysm peak), height (Hp, the vertical distance from aneurysm peak to aneurysm neck plane), aneurysm width (W, the maximal vertical diameter from aneurysm to Hp), aneurysm neck width (N, the maximal vertical diameter from aneurysm neck to Hp), and the diameter of patent artery (Dv). Based on above parameters, the ratio of aneurysm depth to aneurysm neck width (aspect ratio, AR=Hmax/N), the ratio of tumor depth to patent artery diameter (size ratio, SR=Hmax/Dv), the ratio of aneurysm neck width to patent artery diameter (NPR, NPR=N/Dv) and the ratio of aneurysm area to the patent artery area at aneurysm neck (area ratio=Hp × W/(Dv × N)) were calculated.
Diagnosis of intracranial aneurysm rupture: According to the references [9-11], the intracranial aneurysm rupture was diagnosed, the criteria were as the following: the location where subarachnoid hemorrhage is concentrated or the location of hematoma; the ruptured aneurysm indicated by parent artery spasm; surgery results. The rupture rate of 252 patients was calculated.
Analysis of risk factors: The rates of intracranial aneurysm rupture in patients with different clinical characteristics and CTA results were calculated, and the factors with statistical difference were included in Logistics multivariate analysis to conclude the factors that affect intracranial aneurysm rupture.
SPSS18.0 (International Business Machines Corp., New York, USA) was used to analyse the clinical data in this clinical study. The numeration data were presented as (n/%) and χ2 test was used for analysis. The measurement data were presented as (͞x ± s), if the data fit normal distribution t-test was used for analysis and if the data don’t fit normal distribution modified t-test was used for analysis. The factors that affected intracranial aneurysm rupture were included in Logistic multivariate analysis, P<0.05 was considered as statistically significant.
The general data of intracranial aneurysm rupture
In 252 patients, 45 patients were confirmed as intracranial aneurysm rupture during the surgery. The rate of intracranial aneurysm rupture was 17.86%.
Baseline characteristics: The rates of intracranial aneurysm rupture in patients with different age, gender, hypertension and diabetes were statistically different (P<0.05), as shown in Table 1.
|Baseline characteristics||Case number||Case number of intracranial aneurysm rupture (n)||Occurrence rate (%)||P value|
Table 1. Analysis of intracranial aneurysm rupture in patients with different baseline characteristics (n=252).
CTA parameters: The rates of intracranial rupture in patients with different aneurysm diameter, AR, SR, area ratio, aneurysm diameter and irregular aneurysm wall were statistically different (P<0.05), as shown in Table 2.
|CTA parameter*||Case number||Case number of intracranial aneurysm rupture (n)||Occurrence rate (%)||P value|
|Aneurysm neck||<3.151 mm||173||31||17.92||>0.05|
|≥ 3.151 mm||79||14||17.72|
|Aneurysm diameter||<3.850 mm||85||8||9.41||<0.05|
|≥ 3.850 mm||167||37||22.16|
|≥ 2.081 mm||236||42||17.80|
|Irregular aneurysm wall||Yes||125||38||30.40||<0.05|
|Aneurysm location||Posterior Communicating artery||89||18||20.22||<0.05|
|Internal carotid artery||37||9||24.32|
|Anterior cerebral artery||51||5||9.80|
|Middle cerebral artery||59||12||20.34|
|Posterior cerebral circulation artery||16||1||6.25|
|*Note: the mean CTA parameters of 252 were selected as cut-off value.|
Table 2. The relation between CTA parameter and intracranial aneurysm rupture (n=252).
Logistic multivariate analysis
Logistic multivariate regression analysis results showed that complicating with hypertension, the diameter of aneurysm ≥ 3.850 mm, AR ≥ 1.448, SR ≥ 1.388, the area ratio ≥ 1.192, irregular aneurysm wall and the aneurysm locating at posterior communicating artery, internal carotid artery or middle cerebral artery were the independent risk factors of intracranial aneurysm rupture. The age ≥ 60, male patient, complicating with diabetes were the protective factors (P<0.05), as shown in Table 3.
|Risk factor||β||SE (β)||Wald χ2 value||P value||OR||95% CI|
|Age ≥ 60 y||-1.325||0.118||126.086||0.000||0.266||0.211~0.335|
|Aneurysm diameter ≥ 3.850 mm||0.781||0.339||5.308||0.000||2.184||1.124~4.244|
|AR ≥ 1.448||0.265||0.111||5.700||0.000||1.303||1.049~1.620|
|SR ≥ 1.388||0.994||0.135||54.213||0.000||2.702||2.074~3.520|
|Area ratio ≥ 1.192||1.032||0.241||18.337||0.000||2.807||1.750~4.501|
|Irregular aneurysm wall||2.597||0.582||19.911||0.000||13.423||4.290~42.002|
|Location at posterior communicating artery/internal carotid artery/middle cerebral artery||0.891||0.147||36.738||0.000||2.438||1.827~3.252|
Table 3. The multivariate regression analysis of factors that affect intracranial aneurysm rupture.
Intracranial aneurysm is prone to locate at posterior communicating artery or anterior communicating artery branch in Willis circle and this area is located around the subarachnoid space [12,13]. Thus, once there is intracranial aneurysm rupture, there is high risk of spontaneous subarachnoid hemorrhage, which causes high mortality and disability rate [4,14,15]. Therefore, risk assessment of intracranial aneurysm rupture in the early stage is critical in determining the surgical regimen and timing.
Previously most of the studies regarding the risk factor of intracranial aneurysm rupture focused on the baseline characteristics of patients . In this study, the results showed that the patients with age ≥ 60 y, male patient and complicating with diabetes had lower risk of intracranial aneurysm rupture, and the patients complicating with hypertension had higher risk of intracranial aneurysm rupture, which is in accordance with the previous studies [17-19]. Compared with young people, older people's cerebrovascular autoregulation ability is relatively slow, which may lead to intracranial aneurysms more likely to rupture in the elderly ones. The main reasons are: Although among the elderly population the compliance and elasticity of artery are decreased and there is high morbidity of aneurysm in elderly population, the risk of rupture is lower. As the age increases the rupture risk is decreased. It is considered that the decreased risk is related to several protective factors such as decreased blood flow and decreased external stimuli [20,21]. In this study, the risk of intracranial aneurysm rupture in male patients was only 0.671 times of female patients, that is to say, the risk in female patients was 1.5 times higher than male patients, which might be related to that most of female patients were in menopausal status, and menopause is considered to be related to increased risk of intracranial aneurysm rupture. This may be related to endocrine factors. Postmenopausal estrogen levels decreased, causing the content of collagen in tissues to reduce, and thus increasing the brittleness of the vessel wall, so the aneurysm is easy to form and develop. There is also study proposes that estrogenreplacement therapy can effectively decrease the rate of intracranial aneurysm rupture [22,23]; in diabetes patients, there are some pathophysiological changes such as glucose, lipid and protein metabolism disorder, the above changes can cause thickening of capillary basement membrane and atherosclerosis which further increases the risk of intracranial aneurysm. Hyperglycemia is conducive to mononuclear cells into the intima and into foam cells, eventually leading to atherosclerosis, contributing to the occurrence of aneurysms, but the role of aneurysm rupture is not clear. However, in this study, complicating with diabetes was the protective factor of intracranial aneurysm rupture, that is to say, although diabetes can increase the occurrence rate of intracranial aneurysm, it can decrease the risk of intracranial aneurysm rupture. This may be related to that diabetes patients have higher self-management awareness, and there is better timing for the early diagnosis and treatment of intracranial aneurysm. Furthermore, the regular diet and exercise of diabetes patients are helpful to the stability of aneurysm, and the complications in diabetes patients can also cause vicious events before intracranial aneurysm rupture, which can also cause error in statistical results [24-27]; hypertension caused thickening of vessel wall, arteriole hyaline change, smooth muscle cell proliferation of vascular wall, and endothelium damage can decrease the tolerance of vascular wall to blood pressure, and repetitive blood pressure fluctuation impact can gradually cause aneurysm rupture [28-30].
Based on the baseline characteristics, the value of CTA parameters in assessing aneurysm rupture risk was discussed. The results showed that aneurysm diameter ≥ 3.850 mm, AR ≥ 1.448, SR ≥ 1.388, area ratio ≥ 1.192, irregular aneurysm or the aneurysm located at posterior communicating artery/ internal carotid artery/middle cerebral artery could provide reliable reference for assessing the risk of aneurysm rupture. The above characteristics can not only help to assess the aneurysm itself, but also judge some parameters including the blood volume in aneurysm, blood flow speed and average shear stress within the aneurysm, and further predict the rupture risk based on the patent artery. Besides, Huang et al.  found that CTA parameters were independent risk factors from baseline characteristics, thus, CTA parameters combined with patients baseline characteristics can provide more accurate assessment, and further provide a timing and reliable indication for the diagnosis and treatment of intracranial aneurysm.
In conclusion, intracranial aneurysm rupture is closely related to patient age, gender and complication, and CTA parameters can also be applied in predicting the risk of intracranial aneurysm rupture. Thus, the above parameters are hopeful to be applied in predicting the risk of intracranial aneurysm rupture more accurately, however larger sample size is needed to verify the efficacy.
- Aoki T. Future prospects for the development of a novel medical therapy for intracranial aneurysm. Nihon Yakurigaku Zasshi 2016; 148: 86-91.
- Fernandes ST, Alves RV, Doria-Netto HL, Puglia Junior P, Rivau FR, Jory M. Treatment of complex intracranial aneurysm: Case report of the simultaneous use of endovascular and microsurgical techniques. Surg Neurol Int 2016; 7: 1060-1064.
- Al-Jehani H, Najjar A, Sheikh BY. Determining the critical size of intracranial aneurysm predisposing to subarachnoid hemorrhage in the Saudi population. Asian J Neurosurg 2014; 9: 193-195.
- Farag E, Ebrahim Z, Traul D, Katzan I, Manno E. Perioperative management of intracranial aneurysm and subarachnoid hemorrhage. Curr Pharm Des 2013; 19: 5792-5808.
- Kimura H, Akutsu N, Shiomi R, Kohmura E. Subarachnoid hemorrhage caused by ruptured intracranial fusiform aneurysm associated with microscopic polyangiitis. Neurol Med Chir (Tokyo) 2012; 52: 495-498.
- Illies T, Saering D, Kinoshita M, Fujinaka T, Bester M, Fiehler J, Tomiyama N, Watanabe Y. Feasibility of quantification of intracranial aneurysm pulsation with 4D CTA with manual and computer-aided post-processing. PLoS One 2016; 11: 0166810.
- Kapsas G, Budai C, Toni F, Patruno F, Federica Marliani A, Leonardi M, Cirillo L. Evaluation of CTA, time-resolved 4D CE-MRA and DSA in the follow-up of an intracranial aneurysm treated with a flow diverter stent: Experience from a single case. Interv Neuroradiol 2015; 21: 69-71.
- Vaphiades MS, Cure J, Kline L. Management of intracranial aneurysm causing a third cranial nerve palsy: MRA, CTA or DSA? Semin Ophthalmol 2008; 23: 143-150.
- Bui JT, Jajko R, Zivin SP. Massive hemorrhage from arterial access during intracranial aneurysm stent-assisted embolization: endovascular diagnosis and therapy. Semin Intervent Radiol 2015; 32: 14-17.
- Kannoth S, Thomas SV. Intracranial microbial aneurysm (infectious aneurysm): current options for diagnosis and management. Neurocrit Care 2009; 11: 120-129.
- Klepaczko A, Szczypinski P, Strzelecki M, Materka A. Numerical modeling of MR angiography for validation of image-driven quantitative diagnosis of intracranial aneurysm and carotid stenosis. EJNMMI Phys 2014; 1: 63.
- Dengler J, Maldaner N, Bijlenga P, Burkhardt JK, Graewe A, Guhl S, Hong B, Hohaus C, Kursumovic A, Mielke D, Schebesch KM, Wostrack M, Rufenacht D, Vajkoczy P, Schmidt NO, Giant Intracranial Aneurysm Study Group. Perianeurysmal edema in giant intracranial aneurysms in relation to aneurysm location, size, and partial thrombosis. J Neurosurg 2015; 123: 446-452.
- Mackey J, Brown RD, Moomaw CJ, Sauerbeck L, Hornung R, Gandhi D, Woo D, Kleindorfer D, Flaherty ML, Meissner I, Anderson C, Connolly ES, Rouleau G, Kallmes DF, Torner J, Huston J, Broderick JP. Unruptured intracranial aneurysms in the familial intracranial aneurysm and international study of unruptured intracranial aneurysms cohorts: differences in multiplicity and location. J Neurosurg 2012; 117: 60-64.
- Griessenauer CJ, Poston TL, Shoja MM, Mortazavi MM, Falola M, Tubbs RS, Fisher WS. The impact of temporary artery occlusion during intracranial aneurysm surgery on long-term clinical outcome: part I. Patients with subarachnoid hemorrhage. World Neurosurg 2014; 82: 140-148.
- Kimball D, Ples H, Kimball H, Miclaus GD, Matusz P, Loukas M. Fusiform aneurysm of a persistent trigeminal artery associated with rare intracranial arterial variations and subarachnoid hemorrhage. Surg Radiol Anat 2015; 37: 115-118.
- Zhang LT, Wei FJ, Zhao Y, Zhang Z, Dong WT, Jin ZN, Gao F, Gao NN, Cai XW, Li NX, Wei W, Xiao FS, Yue SY, Zhang JN, Yang SY, Li WD, Yang XY. Intracranial aneurysm risk factor genes: relationship with intracranial aneurysm risk in a Chinese Han population. Genet Mol Res 2015; 14: 6865-6878.
- Park J, Son W, Park KS, Kang DH, Shin IH. Intraoperative premature rupture of middle cerebral artery aneurysms: risk factors and sphenoid ridge proximation sign. J Neurosurg 2016; 125: 1235-1241.
- Chen JX, Lai LF, Zheng K, Li GX, He XY, Li LP, Duan CZ. Influencing factors of immediate angiographic results in intracranial aneurysms patients after endovascular treatment. J Neurol 2015; 262: 2115-2123.
- Schneiders JJ, Marquering HA, van den Berg R, Van Bavel E, Velthuis B, Rinkel GJ, Majoie CB. Rupture-associated changes of cerebral aneurysm geometry: high-resolution 3D imaging before and after rupture. AJNR Am J Neuroradiol 2014; 35: 1358-1362.
- Ben Mrad M, Derbel B. An infected false aneurysm of the subclavian artery in a 41-year old drug abuser. Pan Afr Med J 2015; 22: 211.
- Fathi NQ, Syahrilfazli AJ, Azizi AB, Redzuan IM, Sobri M, Kumar R. Ruptured giant left distal anterior cerebral artery aneurysm in a two-month-old baby. Pediatr Neurosurg 2015; 50: 275-280.
- Harrod CG, Batjer HH, Bendok BR. Deficiencies in estrogen-mediated regulation of cerebrovascular homeostasis may contribute to an increased risk of cerebral aneurysm pathogenesis and rupture in menopausal and postmenopausal women. Med Hypotheses 2006; 66: 736-756.
- Tada Y, Wada K, Shimada K, Makino H, Liang EI, Murakami S, Kudo M, Shikat F, Pena Silva RA, Kitazato KT, Hasan DM, Kanematsu Y, Nagahiro S, Hashimoto T. Estrogen protects against intracranial aneurysm rupture in ovariectomized mice. Hypertension 2014; 63: 1339-1344.
- Takagi H, Takuya U. Association of diabetes mellitus with presence, expansion, and rupture of abdominal aortic aneurysm: Curiouser and curiouser! cried ALICE. Semin Vasc Surg 2016; 29: 18-26.
- Takagi H, Umemoto T. Negative association of diabetes with rupture of abdominal aortic aneurysm. Diab Vasc Dis Res 2016; 13: 341-347.
- Theivacumar NS, Stephenson MA, Mistry H, Valenti D. Diabetes mellitus and aortic aneurysm rupture: a favorable association? Vasc Endovascular Surg 2014; 48: 45-50.
- Tsai CL, Lin CL, Wu YY, Shieh DC, Sung FC, Kao CH. Advanced complicated diabetes mellitus is associated with a reduced risk of thoracic and abdominal aortic aneurysm rupture: a population-based cohort study. Diabetes Metab Res Rev 2015; 31: 190-197.
- Hosaka K, Downes DP, Nowicki KW, Hoh BL. Modified murine intracranial aneurysm model: aneurysm formation and rupture by elastase and hypertension. J Neurointerv Surg 2014; 6: 474-479.
- Tsai FY, Yen A, Guo WY, Wu CC. Venous hypertension and cerebral aneurysm rupture. Neuroradiol J 24, 137-144
- Hu P, Wang J, Fan XC, Hu B, Lu L. Hypertension triggers the rupture of coronary artery aneurysm in an 8-year-old boy with Kawasaki disease. J Clin Hypertens (Greenwich) 2014; 16: 766-767.
- Huang ZQ, Meng ZH, Hou ZJ, Huang SQ, Chen JN, Yu H, Feng LJ, Wang QJ, Li PA, Wen ZB. Geometric parameter analysis of ruptured and unruptured aneurysms in patients with symmetric bilateral intracranial aneurysms: a multicenter CT angiography study. AJNR Am J Neuroradiol 2016; 37: 1413-1417.

domain: literature


text:
This system will be undergoing maintenance Tuesday, March 28 from 1:00 PM to 3:00 PM CST
Corpus Christi Caller and Daily Herald (Corpus Christi, Tex.), Vol. SEVENTEEN, No. 2, Ed. 1, Monday, December 7, 1914
(Listing Multiple Pages).
This newspaper has 16 pages. Select a thumbnail to view a larger version.

domain: news


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Villa Ionio offers cheerfully decorated studios, 100 metres from Ammoudia sandy beach. Preveza is at 45 km and Parga at 20 km. Only 50 metres away, Ammoudia village features cafes, bars and fish taverns.
The recently refurbished studios have air conditioning and heating, a satellite TV, and kitchenette with kitchenware and refrigerator. Their balconies come with table and chairs and offer a garden view.
Active guests have many opportunities for inland trips, including walks along the banks of Acheron River, boat trips, excursions and water sports. The pebbled beach of Alonaki is at 5 km, and the sandy beach of Keretza at 6 km.
An ATM can be found 100 metres away. The hotel offers a 24-hour reception desk, and BBQ evenings are hosted at the garden. Guests can also visit hotel's library. Free WI-FI is available throughout the property and free public parking is available on site.

domain: travel


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Laser Treatment for Toenail Fungus
posted: Nov. 11, 2022.Toenail fungus and some form of onychomycosis is a condition that affects nearly 25 million Americans and Laser Treatment is effective in approximately 90% of all cases. Many who have Read more
Solutions For Toenail Fungus
posted: May 28, 2020.Onychomycosis is the technical term for toenail fungus. It’s when fungus gets under the nail and causes an infection. You’ll notice that the nail changes color and starts emitting an Read more
What Causes Toenail Fungus?
posted: Nov. 27, 2019.Toenail fungus is a common problem that can be rather challenging to get rid of. While toenail fungus can happen to anyone it most often occurs in older adults. If Read more
Treating Toenail Fungus
posted: Nov. 01, 2018.Treating toenail fungus Toenail fungus--it's one of the most common podiatric problems children, teens, and adults have. Causing thickened, yellow, brittle nails, onychomycosis (the medical name for toenail fungus) spreads easily Read more

domain: medical


text:
Quickly exit this site by pressing the Escape key Leave this site
This site is a beta, which means it's a work in progress and we'll be adding more to it over the next few weeks. Your feedback helps us make things better, so please let us know what you think.
Six males were arrested in connection with alleged drugs offences after officers attended an address on Tilery Road in Stockton on Sunday 22nd January.
Officers from the Operational Support Unit (OSU) entered the property and seized suspected class A and B drugs, over £1000 in cash, pepper spray and a zombie knife.
Six males in the property aged 16, 17, 24, 28, 28 and 34 were arrested in connection with the incident.
All have been bailed with conditions whilst enquiries continue.
Anyone with information regarding drugs activity in their local area is asked to contact Cleveland Police on 101, or Crimestoppers anonymously online at www.crimestoppers-uk.org or by calling 0800 555 111.

domain: law


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Here’s a trailer for the HBO documentary about evolution and religion that I mentioned a while back:
The film was made by Antony Thomas, who is a very prominent documentary filmmaker from England. I was one of the talking heads interviewed for the film, and Antony wrote to tell me that some of my interview made it into the final cut. Yay me! I have not seen the finished film, but from our conversations I am confident it will not suggest that creationism has any scientific credibility whatsoever.


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Justice Minister Bekir Bozdağ yesterday issued a comprehensive directive for the Police Department, asking police and gendarmerie officers to better protect women facing physical or emotional harm.
In the directive, he said preventing violence against women was one of the key tenets of the government, noting that its rise was one of the main factors threatening family harmony. Bozdağ said security forces had to improve their response to cases of violence against women.
"In recent years, violent attacks, especially against women, have risen to dramatic levels. Such attacks create shockwaves within the society. Printed and visual media report instances of beatings, torture and murder. The primary victims are women and children," Bozdağ said.
The issue should be accepted by security forces as a key matter of state, he said, adding that the failure to properly implement the current law for protecting families and women was one of the main impediments to saving lives.
He said officers needed to visit the homes of those under protection at least once a week and needed to be in constant contact with victims' close family members like grandfather, uncle, aunt or others. The neighbors of women under protection need to be consulted and the vicinity of homes are required to be under constant surveillance. Reports prepared should be submitted to the National Judicial Network judiciously.
Bozdağ also asked police and gendarmerie officers to initiate protective measures as soon as the legal process begins and tell the protected individual to ensure that he or she immediately alerts the authorities whenever he or she feels threatened.

domain: sociology


Ullman introduces bill to mandate insurance coverage for COVID-19-related medical interventions
DOYLESTOWN, Oct. 27 – State Rep. Wendy Ullman, D-Bucks, is introducing legislation that would mandate insurance coverage, without patient cost-sharing, for all costs related to COVID-19 testing, therapies and preventions.
“Every Pennsylvanian has a right to expect protections from COVID-19,” Ullman said. “These protections should include safeguarding people from debilitating financial costs as a result of medical interventions for COVID-19. The fear of incurring medical debt should not be a factor that inhibits individuals from seeking necessary life-preserving care.”
If passed, the legislation would enable Pennsylvanians to seek care for COVID-19 without having the expectation for any out-of-pocket payments.
“The pandemic has been devastating on families economically,” Ullman said. “We don’t want people refusing hospital care because they are afraid of burdening their families with crippling medical debt and so risk their lives as well as potentially spread the virus to others in their family and the community.
“When a vaccine for COVID-19 is rolled out,” Ullman said, “we want everyone to be vaccinated without having to worry whether they can afford it.”
Ullman’s legislation is the first to be introduced regarding insurance coverage requirements for COVID-19 that are directly related to COVID-19 diagnosis and treatments.


Before their stellar performance on Later… with Jools Holland last night, we couldn’t resist an appropriately placed photo with Future Islands.
Future Islands make their UK television debut on Later with Jools Holland tonight from 10pm GMT, on BBC2.
The first release on 4AD by D.D Dumbo will be his ‘Tropical Oceans’ EP, released digitally on 28th October, with vinyl following in November.
Merchandise’s US tour with Lower is now underway.
You can find all other upcoming US and EU dates here: http://www.4ad.com/artists/merchandise/live
The official video for Ariel Pink’s ‘Put Your Number In My Phone’ is now streaming.
Directed by Grant Singer, the video is released alongside three special tour dates in New York, London and LA. All details here, along with links to pre-order new album ‘pom pom’ [x]
You can now listen to the Wolfgang Tillmans’ curated ‘Music of the band (1982-1987) in order.
The title track from Lo-Fang’s forthcoming ‘Every Night’ mixtape.
This week 4AD is Muzu’s Label in Focus.
Watch their intro playlist here [x]


police style12″ friction expandable
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The complex genome of the potato, after five years of work, has now been sequenced by genetic scientists. According to scientists, it could lead to the rapid development of a gamut of disease-resistant varieties.
The potato is considered to be the world’s fourth most important food crop, so it is vital for world food security, especially as we head towards a world population of 9 billion. The genome of the potato is a highly heterozygous autotetraploid, which means there are four copies of every chromosome. Apparently the potato consists of more than 39,000 protein-coding genes.
Potatoes are growing in importance, especially in so called developing countries. They are surprisingly economical when compared to other major food crops such as rice, wheat and maize (also known as corn).
In order to form the Potato Genome Sequencing Consortium, twenty-six research institutes around the world united. The project has resulted in several important findings, one of the most important of which is the identification of more than 800 genes related to disease-resistance. These genes could be beneficial for fighting several devastating diseases such as potato cyst nematode and potato blight.
Findings have also suggested that singling out these genes will make it easier to develop new varieties of the humble yet complex potato. Scientists have indicated that genome sequencing of the potato will assist in improving its quality, nutritional value, and yield. It could help to reduce the amount of time required to breed new varieties.
It is worth noting that sequencing the potato genome does not necessarily mean radical genetic engineering of the potato has to ensue, although it’s possible. Sequencing could be used to improve usual breeding techniques, with the aim of making plants more resilient in various ways.
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domain: agronomy


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LeanGard® Protein Drink Mix
LeanGard® protein drink mix is a perfect combination of high quality soy protein isolate and whey protein fortified with essential daily required vitamins, minerals along with natural herbs, antioxidants and dietary fibres. It provides an ideal balance of protein and nutrition without overloading unnecessary fat and calories.
Weight management is a key factor in preventing overweight and obesity. Even after weight loss, unless a proper diet is followed, the lost weight is regained. To combat this problem a low calorie diet is usually prescribed. An increase in the amount of protein in the diet contributing to the total caloric requirements is found to help in weight management.
Digestive Intolerance Blend (DIB) is a proprietary product of Sabinsa Corporation which contains the digestive enzymes lactase and protease, LactoSpore® which is a probiotic.
- Increases lean body mass
- Helps in weight management
- Increases satiety
- Prevents lactose intolerance
- Enhances protein digestion
- Reduces the load on the kidneys
- Helps to maintain good gut health
- Provides easily absorbable minerals
- Decreases the serum cholesterol and triglyceride levels
- Stabilizes the post prandial blood glucose level
- Reduces the rise of blood glucose level following a meal
|Ingredient||100g||Serving size of 25g|

domain: food


text:
If you are a passionate artist or someone who loves to express their emotions through art, you might have come across the Sad Drawing Ideas APK. This mobile application has gained popularity among art enthusiasts, especially those who enjoy creating drawings that evoke deep emotions and feelings. This article will examine what Sad Sketching Ideas Mod APK is, its features, how to use it, and how it can benefit you.
Sad Drawing Ideas APK is a mobile application that provides users with various drawing ideas that revolve around sad themes. It is a free app that is available for download on Android devices. The app features a collection of unique and inspiring drawing ideas that cater to different skill levels, from beginner to advanced. The Sad Drawing Ideas APK Mod is a platform for artists to explore their creativity and a tool to help them express their emotions through art.
|App Name||Sad Drawing Ideas ModAPK|
|Last Updated||One Day Ago|
|Developer||Sad Drawing Ideas|
|Operating System||Android 4.4 and up|
|Category||Art & Design|
|Content Rating||Rated for 12+|
|Language||English, Spanish, French, and more|
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Sad Drawing app can be used offline, making it convenient for artists who prefer to work on their art without an internet connection. Users can access the drawing ideas even when not connected to the internet. This feature makes it easy for artists to work on their art anywhere, anytime, without worrying about internet connectivity.
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The Download Sad Drawing Ideas Mod APK allows artists to customize their settings according to their preferences. Artists can set the app to display specific categories of drawings, such as sad or emotional, and customize the app’s layout.
The app provides high-quality images of drawings, making it easy for artists to study and recreate them. The clear and detailed photos provide artists with an excellent reference for their artwork.
Free to Use
The Sad Drawing Ideas APK Download is free to use, making it accessible to all artists. This feature ensures that artists of all skill levels have access to inspiration and ideas for their drawings without paying for them.
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The app allows artists to share their artwork on social media platforms like Instagram, Twitter, and Facebook. This feature enables artists to showcase their work to a broader audience and get feedback from other artists.
How Can Sad Drawing Ideas Mod APK Benefit You?
Sad Drawing Ideas Mod APK Download is a mobile application that provides a collection of drawing ideas that revolve around sad themes. It is an excellent tool for artists and art enthusiasts who want to express their emotions through art. This article will explore how Sad Drawing Ideas APK Latest Version can benefit you.
One of the most significant benefits of using Sad Drawing Ideas Mod APK Latest Version is that it inspires artists looking for new ideas. The application has a vast library of drawing pictures that cater to different emotions and moods. Each drawing concept is unique and inspiring, providing artists with an opportunity to create art that is emotionally charged and thought-provoking.
The app is regularly updated with new drawing ideas, ensuring that artists always have access to fresh and exciting ideas to explore and create. The constant flow of new ideas helps artists stay motivated and engaged, encouraging them to keep making art that reflects their emotions and experiences.
Helps Express Emotions
Sad Drawing Ideas for Mobileis an excellent tool for artists who want to express their emotions through art. The app features a range of themes, including loneliness, heartbreak, grief, and many more. Each drawing idea is designed to evoke a particular emotion, helping artists express their feelings creatively and meaningfully.
Through art, artists can process their emotions and experiences, gain clarity, and find closure. Sad Drawing Ideas for Android provides a platform for artists to explore and express their feelings, helping them heal and grow.
Sad Drawing Ideas App APK is an excellent tool for boosting creativity. It allows artists to explore different themes, techniques, and styles. The app’s extensive collection of drawing ideas encourages artists to experiment with other mediums, procedures, and styles, helping them develop their artistic skills and expand their creative horizons.
The app’s user-friendly interface and easy-to-navigate menus make it easy for artists to explore and discover new ideas, inspiring them to create art that is both unique and emotionally charged.
Convenient and Accessible
Sad sketching is a convenient and accessible tool for artists. The app can be used offline, making it easy for artists to work on their art anywhere, anytime, without worrying about internet connectivity. The app’s user-friendly interface and easy-to-navigate menus make it easy for artists to browse drawing ideas and find inspiration.
Pros & Cons
- Emotionally charged drawing ideas
- Regularly updated
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- It can be used offline
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- Limited to sad themes
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If you want to download Sad Drawing Ideas Mod APK, follow the steps below.
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The Sad Drawing Ideas APK Download Free is a must-have app for artists who want to express their emotions through art. The app has become a favourite among artists with its user-friendly interface, a wide range of ideas, daily updates, customizable settings, high-quality images, and social media integration. And the best part? It’s completely free to use!
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Every so often, MT poses 60 questions to a local or visiting artist in Toronto who has made our classical music community that much more interesting. They pick and choose. The minimum response is 20 answers. A kind of Rorschach personality test, if you will.
Alexander Shelley was appointed Music Director-designate of Canada’s National Arts Centre Orchestra in October 2013 and begins his new role of Music Director in September 2015. The same year also marks his seventh year as Chief Conductor of the Nuremberg Symphony Orchestra where he has played a pivotal role leading the orchestra’s education work and touring activities. On January 20, 2015 Shelley was named Principal Associate Conductor of London’s Royal Philharmonic Orchestra.
If I had a hangover this morning, hypothetically, what would you recommend?
Oh! I suppose that depends what it’s from–whether it’s from hard liquor or wine or beer. Good question, though. And it depends on where you want to go with your day. Maybe some Bach? Or some purring minimalism? Something without many peaks or troughs, unless you want to feel those and then I’d say maybe Wagner–Tristan? Death and Transfiguration? The question is where do you want your hangover to take you?
How much do you like Mendelssohn?
I love Mendelssohn but I have to add the disclaimer that there’s no composer who I’ve really studied that I didn’t come to love. But Mendelssohn is part of my core, my spine, the Austro-German tradition from Bach to Mahler, and he’s part of that evolution. Also he was a prodigy who retained his energy–not that he got to be very old–but he was still in command of the freedom of youth, and he was still able to turn a pure phrase.
What do you like to do in Ottawa?
Well, I like to make music there. But it surprised me, and perhaps it shouldn’t have, but the number of different and fantastic restaurants there are. Also I love walking up the river and looking across at Parliament. Coming from London, where I live, Ottawa feels like there’s a constant contact with nature. So, fresh air, music, and friends.
What are you reading right now?
Gödel, Escher, Bach by Hofstadter. I get so into books that I will reread whole chapters to make sure that I understood them, and this is a brick of a book. But I’m not giving up. It comes after a Bertrand Russell binge of the last few years, starting with his History of Western Philosophy. I tend to move between books at the same time. I’m a book polygamist.
What’s the last exhibit you saw?
The last exhibition I visited was a tiny presentation of beautiful behind the scenes photographs from a recent production of La Traviata in Leeds at Opera North where I have been performing Figaro… and I’m planning on seeing the Rubens show in London in the next couple of weeks.
And who’s the living musical figure that you most admire?
I heard the Berlin Philharmonic here four or five days ago with Simon Rattle conducting. I’ve respected him massively for years, of course, as a musician, and recently I’ve been reading all the articles that have been coming out about the LSO and how London needs a better hall. Rattle met with the City and the mayor, Boris Johnson, and he’s persuaded them all. I think that’s very important to be inspirational and definitional musically, but also to fulfil a political role.
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Toilet not working
Reported via Android in the Public toilets category by Paul Hennessy at 18:48, Wed 9 August 2017
Sent to Hillingdon Borough Council 2 minutes later
Not working for long time be nice if it was removed it's a eyesore
This report is now closed to updates. You can make a new report in the same location.


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This long standing single story industrial building has a corrugated metal, sloping gable roof capped by a rectangular monitor.
Historical Significance: The present Auburn Iron Works has been operating as a blacksmith's shop in the same locality for over one hundred years. By 1888 George Allen and Joseph Sandhorfer had established this shop at Auburn Station, becoming one of the first blacksmith businesses to operate near the Central Pacific Railroad Station. At that time, the main part of Auburn was one mile to the southwest. Auburn Station, or East Auburn, was just starting to develop.
Although the business, as well as the property the shop is on, has changed ownership several times through the years, it has always been run as a blacksmith shop. At times, other services such as wagon making, harness making, wood working and automobile repairing were offered in conjunction with blacksmithing, but it is the blacksmithing which is ongoing today. Built over the Boardman Canal, this shop may well be the oldest continuously operating blacksmith shop in northern California and it continues to provide a necessary service to the community. It is an excellent example of a once common and vital trade that has largely been displaced due to the many changes in automation and technology.

domain: history


text: The gut hormone ghrelin is involved in feeding behaviour. It increases appetite and food intake when administered by intravenous infusion to subjects of normal weight. Ghrelin levels are often lower in obese than lean individuals and whether responsiveness to ghrelin differs in lean and obese people is not known. We investigated whether obese human subjects are sensitive to the effects of ghrelin. Approval of the local ethics committee was obtained. We examined the effects of intravenous infusions of ghrelin at 5.0 pmol/kg/min and 1.0 pmol/kg/min in 12 healthy lean subjects (mean BMI 20.5 plus/minus 0.17 kg/m2) and 12 healthy obese subjects (mean BMI 31.9 plus/minus 1.02 kg/m2), in a randomized, double-blind, placebo-controlled study. Ghrelin infusion lasted 75 minutes with a buffet meal served at 45 minutes. Low-dose infusion of ghrelin significantly increased ad libitum energy intake at the meal in the obese group only (mean increase 36.6 plus/minus 9.4%, p<0.01.) High dose ghrelin infusion increased energy intake in both groups (mean increase 20.1 plus/minus 10.6% in the lean and 70.1 plus/minus 15.5% in the obese, p<0.01 in both cases.) In the obese group the scoring of palatability of food was increased by 17.5 plus/minus 7.4% with low-dose ghrelin and 21.3 plus/minus 8.7% with high-dose ghrelin, compared to saline (p=0.04 in both cases.) No significant change in palatability was seen in the lean group. In addition, the growth hormone response in the obese group is blunted at both doses of ghrelin administered. Obese people are sensitive to the appetite-stimulating effects of ghrelin and inhibition of circulating ghrelin may be a useful therapeutic target in the treatment of obesity.


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Now more than ever, couples are opting for domestic honeymoons instead of international ones. Traveling within the U.S. is easier, less costly, and can be as romantic and exciting as international travel — you just have to choose the right destination. Consider a Cape Cod honeymoon to celebrate your marriage! The Cape is a great honeymoon spot for couples looking for a quiet romantic getaway. Our area is filled with great ways to make memories with your special someone. From a magical visit to Martha’s Vineyard to an intimate stay at a Cape Cod bed and breakfast, there’s no shortage of romantic things to do in the area. Read on to learn about some of our favorite romantic things to do on the peninsula!
When you’re ready to start planning your romantic getaway, request our Cape Cod Vacation Guide. This free resource is filled with local insight and tips to help you plan the honeymoon of your dreams!
Your Guide to an Unforgettable Cape Cod Honeymoon
Plan your dream honeymoon to Cape Cod with the helpful tips below. Also, be sure to read this Wedding Wire article for more information on the top sights and activities for your honeymoon on the Cape!
Browse Romance Packages
Your honeymoon is the time to splurge. We leave no stone unturned when it comes to making sure your romantic getaway is perfect. That’s why our bed and breakfast offers a variety of fanciful add-ons and extras to enhance your stay. Choose from a bottle of red or white wine, chilled champagne or Prosecco, a dozen long-stemmed roses, and handmade chocolates. These small details can take your Cape Cod honeymoon to the next level!
Visit Martha’s Vineyard
Martha’s Vineyard is a must-see on your Cape Cod romantic getaway. This small island off the coast of Cape Cod is the perfect destination for a day trip! Here, you can enjoy fresh seafood, boutique shopping, explore lighthouses, and more. The sunset ferry ride from Falmouth back to Cape Cod is another plus of taking a Martha’s Vineyard day trip from Cape Cod!
Plan a Romantic Stay at Candleberry Inn
Candleberry Inn is one of the most romantic hotels on Cape Cod. Our bed and breakfast is centrally located in Brewster on Route 6A, so it’s just a short drive away from anything you wish to do on the peninsula. Cozy up in your romantic guest room at Candleberry Inn after a day of spending time exploring the Cape with your special someone.
Consider a stay in the Garden Suite during your romantic getaway. This premium room boasts a king-size bed, a private bathroom with a walk-in shower and a JACUZZI® soaking tub-for–two, and a coastal-themed sitting area. This suite-style room also features a private patio with outdoor seating. It’s the perfect place to chat over a morning cup of coffee or evening glass of wine!
Check our availability to start planning the Cape Cod honeymoon of your dreams!

domain: geography


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Talking about CAD, it is the 3letter ISO code given to the official currency of Canada- the Canadian dollar. Apart from Canada, it is also unofficially used by Saint Pierre and Miquelon. Cent is the smaller unit of dollar where 1 unit of CAD is subdivided into 100 cents.
Fxkart has been serving foreign travellers since January 2015. It has not been very long but in this short period itself, fxkart has been honored with a lot of recognitions from India. Aurangabad has been one of the locations from where we have been able to satisfy a lot of foreign travelers through our forex deals.
Travellers who are planning their trip from Aurangabad to Canada are now at the right place. This very website will help you know best exchange rates for CAD forex from some RBI authorised forex agents of Aurangabad.
The 3F formula keeps Fxkart ahead of others of its kind.
Aurangabad users of our website can buy CAD currency notes as well as CAD travel cards.Though travel card is a more frequently used forex yet currency notes have not become out of use. We do need currency notes for daily unplanned expenditure during our Canada trip.
Fxkart reaches to the Aurangabad customers with these products for absolutely free of cost. There should be no worries concerning any membership fee or other hidden charges as such.
We have been giving stress on customer care support since we strive hard to solve our customers’ problems. Apart from emails and phone calls we have installed two new features online chat and call back request.
Also, an added advantage of availing our services at fxkart is the doorstep delivery plan. You can opt for the CAD currency to be delivered at your place in Aurangabad for free or you can collect it from the store itself.
Going forward we guarantee you a pleasant experience while getting your Indian rupee currency converted into a dollar.
4 Major reasons to use Fxkart
|Currency||Buy Rate||Sell Rate|
"Being my first abroad travel, I did not have much idea about foreign exchange and would have ended up paying a lot more than required, was it not for the experts at FxKart. They guided me expertly to the best deals. The team was really helpful and they are solving the problem in a very good way. Kudos and Best of luck to the team!!!"
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domain: finance


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We delivered Our Chefs choice bucket to SA Chefs Academy for the competition. Khoisan was chosen as it is the only hand-harvested natural Sea Salt in South Africa. It also has a fantastic taste !
This is an easy weeknight traybake of chicken pieces in white wine with onions and garlic. The chicken is seasoned with Khoisan’s seaweed & herb salt.


text: I am in the process of replacing a garden bed for my mother that has been overtaken by running bamboo. I have dug out all the dirt and want to use that to refill the bed. But I am worried about all the little pieces of bamboo roots. I am sieving the soil and removing as much of the roots as I can, but it is a very arduous task. If I just remove the larger pieces, will small pieces of running bamboo grow again once the soil is wet and yummy?

domain: hobby


BALASORE: Indian army on Monday successfully conducted a user trial of medium range supersonic Surface-to-Air Missile (SAM) Akash from a defence base off the Odisha coast. The missile was fired targeting a pilot-less target aircraft (PTA).
The test was conducted days after the army declared the weapon system a ‘dud’ and expressed its reluctance to accept the missile. After getting two regiments of Akash missiles with six firing batteries worth over Rs 15,000 crore, the army had claimed that the missile could not provide desired results on field.
The Defence Research and Development Organisation (DRDO), which had developed the missile indigenously, seemed to be undeterred over the sudden change of mind of the army which is now planning to procure Israeli systems. According to the DRDO officials at Hyderabad, Akash missile is the only missile of its kind now available in the world.
Besides providing the army and air force for the battle field support, DRDO is all set to export the weapon system to the countries which have shown interest on it. “It is a useful weapon for both the army and air force and first successful model of the ‘Make-in-India’ initiative. The armed forces are scheduled to carry out a couple of more tests in next few days,” they informed.
The missile was launched from the launching complex-III of the Integrated Test Range (ITR) at Chandipur-on-sea at about 12.35 pm. The test was aimed at gauging the flight consistency and effectiveness of the missile besides ascertaining the serviceability of the system in various conditions.
A defence official from New Delhi said the mission boosted the air defence shield of the country and re-validated the weapon’s operational efficiency. The missile was aimed at intercepting the aerial vehicle 'Banshee' at a definite altitude over the Bay of Bengal. The entire flight of Akash was captured by electro-optical tracking systems, he informed.
Akash is a medium-range surface-to-air missile and it can reach targets 30 km away. The 5.8-metre-long sleek missile has a launch weight of 720 kg and can carry a warhead of 50 kg. The missile is crucial to India's air defence programme as it will be used to counter ballistic and cruise missiles, enemy aircrafts and air-to-surface missiles.
The Akash missile system which is similar to the American Patriot air-to-surface missile system can track 64 targets simultaneously and the inbuilt radar can provide command to the launcher to fire 12 missiles at a time. The development of Akash missile had taken place under the country’s Integrated Guided Missile Development Programme (IGMDP) three decades ago. Akash was formally inducted in the Army on May 5 and in the Air Force on July 10 last year.


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The Inaugural mass on the 3rd January was followed by the staging of the play “The Guardian Angel” which portrayed the life of St Claudine Thevenet the Foundress of the Congregation of Jesus and Mary. I was fortunate to attend this on the 7th January, 2009. Ms. Meher Pudumjee, CEO of Thermax, was the Chief Guest and made an inspiring speech for the young students. The programme was staged by 1300 students and it was extremely professional and very well portrayed. It took one back to the 1770’s when St. Claudine started the Congregation. Her last words “How Good God Is” summarizes everything.
The future programme outline is as follows :
2009 Feb: Workshops and Seminars, Foundress Day; 2009 March: Workshops and Seminars; 2009 April: Musical Housie and Summer Camp; 2009 June: Tree Plantation, Workshops and Seminars; 2009 July: Blood Donation Camp, Annual Day for Grand Parents; 2009 August: Interschool Quiz and Elocution Competition, Folk Dance Competition/Inter Faith Dialogue; 2009 September : Interschool Painting competition, Teachers’ Day; 2009 October: Dandiya & Six a side rink hockey, Interschool tele matches, Interschool mini-olympics; 2009 November : Parents Night, Magazine & Calendar 2010, Children’s’ Day; 2009 December: Fete; 2010 January: Thanks Giving Mass, Cultural Programme, Release of Magazine and Calendar. All in all, a packed year!
To mark the occasion, a calendar, the school souvenir and a mug with “150 years” printed on it were on sale. Needless to say, these items were selling like hotcakes.


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Diana Johnstone is an astute and longtime analyst on global affairs, whose highly readable memoir is peppered with insights on the world events she experienced, reported on and sometimes participated in—from the Viet Nam War to today’s Yellow Vest movement in France. This mixture of autobiography and history encompasses both the personal evolution of a spirited American journalist and her keen insights into the major events of the last half century whose rectitude and indeed legality she most frequently decried. Circle in the Darkness revisits many of its key events, adding insights with the benefit of hindsight. It covers:
- early anti-war protests against the Viet Nam War in the United States,
- student days in Yugoslavia,
- life in the international press milieu in Germany during the Cold War,
- May ’68 in France,
- the turbulent politics of Italy in the 1970s,
- the impact on Europe of the criminal Middle East wars,
- the decline of French intellectuals from Sartre to Bernard Henri Lévy,
- the massive popular movement in the 1980s against deployment of U.S. nuclear missiles in Europe,
- the transformation of Europe’s Green Parties from a leading force for peace to apologists for war on grounds of “human rights”,
- today’s Yellow Jacket movement that threatens the toppling of France’s Macron government and marks a popular awakening to the lies of politicians and media in this long night of criminal deception.
She recounts the rise and fall of antiwar sentiment in the Western left from its resistance to the Viet Nam War to its acceptance of so-called humanitarian wars. Having served for six years as press officer of the Greens in the European Parliament, she enjoyed an exceptional vantage point from which to observe and analyze the role of the European Union in sacrificing democracy to the demands of technocratic neoliberal globalization. Making no secret of her personal viewpoints, while scrupulous in her respect for the facts, Diana Johnstone blames the gullible ignorance of a self-satisfied “left” for providing moral cover for NATO’s role in the criminal destruction of Yugoslavia and Libya, as well as for the destructive Western intervention in Syria.
While so doing, she exposes the realities of the process called Globalization, which aggravates economic inequalities by unleashed capitalism and replaces diplomacy with threats, sanctions and military intervention, has led to a drastic reduction of democracy in the “democratic” West.

domain: library


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Booking Summer Weeks July & August, Available for a Longer Term Winter Rental
- Airport Shuttle
- Pets Allowed
- Swimming Pool
- Smoking Allowed
Just about the best views/spot in Jamestown! Walk to the water across the street at the East Ferry shoreline Beach in the Shoreby Hills area and walk to the Village of Jamestown.
The first floor has an open floor plan with living/dining, kitchen, screened in porch, den with bathroom shower only, laundry room. There is a bonus room tucked away on the 2nd floor above the garage with two twins and a lavette. The 2nd floor offers a master with a king size bed and a private bath with Tub/Shower. The second bedroom with two full size beds and a private bath with Tub/Shower.
The screened porch is just wonderful, sit and enjoy at any time of the day. The yard is large for summer games. The garage is available for tenant use. We provided bedding, linens and towels. ( Bring beach towels they seem to disappear after some summer tenants) The kitchen is fully stocked and has new appliances, the pantry and laundry room have additional supplies.


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Anxiety is one of the most common mental health issues worldwide, affecting millions yearly. It can lead to several adverse effects on a person’s personal and professional life. Anxiety disorders can be challenging to navigate, and if not treated properly, they can lead to more severe consequences such as substance abuse and addiction. However, with proper treatment for anxiety, individuals can effectively manage their symptoms and lead a fulfilling life. Contact our compassionate team at Virtue Recovery Killeen by dialing 866.843.0545 to explore how anxiety affects personal life, the co-occurrence of anxiety and addiction, and the benefits of anxiety treatment for those struggling with addiction.
What Is Anxiety?
Anxiety is a natural response to stress and can be beneficial in many situations. It can keep you alert and focused, which can help you avoid dangerous situations. However, if you experience anxiety frequently or excessively can be a sign of an anxiety disorder. Anxiety disorders include a variety of mental health conditions, such as:
- Generalized anxiety disorder (GAD)
- Panic disorder
- Social anxiety disorder
- Specific phobias
- Obsessive-compulsive disorder (OCD)
Anxiety disorders can cause physical symptoms such as rapid heartbeat, excessive sweating, and muscle tension. They can also lead to cognitive symptoms such as excessive worry or fear. However, there is a difference between experiencing regular anxiety and living with an anxiety disorder. Regular anxiety is a natural part of life and helps protect us from potential threats. Anxiety disorders, on the other hand, can be debilitating and interfere with daily life.
Can Anxiety and Addiction Co-Occur?
Anxiety and addiction can co-occur, meaning they can happen simultaneously. Substance use can temporarily relieve anxiety symptoms, making individuals more likely to continue using drugs or alcohol to cope. However, substance use can increase anxiety symptoms, leading to a vicious cycle of drug abuse and anxiety. Co-occurring anxiety and addiction require specialized treatment to address both conditions simultaneously.
How Else Can Anxiety Affect Your Personal Life?
The effects of anxiety can be far-reaching. Anxiety can result in a reduced quality of life, strained relationships, and even physical health problems. Anxiety can make it challenging to engage in everyday activities, such as going to work or school. It can also lead to avoidance of social situations, impacting the ability to form relationships. Anxiety can also lead to health problems such as high blood pressure and heart disease.
Benefits of Anxiety Treatment for Those Struggling with Addiction
Anxiety treatment can be beneficial for those struggling with addiction in the following ways:
- Proper anxiety treatment can help individuals to manage their symptoms and reduce the likelihood of turning to drugs or alcohol for relief.
- Anxiety treatment can also help individuals develop coping strategies to manage anxiety in their everyday lives.
- Anxiety treatment can lead to improved relationships and an enhanced quality of life.
- Anxiety treatment can help individuals to make better decisions, leading to a reduction in negative consequences related to substance abuse.
- Anxiety treatment can help individuals better understand their condition and how to manage it, leading to a more fulfilling life.
At Virtue Recovery Killeen, we prioritize the care and comfort of our patients. Our team is here to provide a safe space for individuals to seek help for anxiety and addiction. We understand that co-occurring disorders require specialized treatment, so we offer personalized treatment plans tailored to each individual’s needs.
Find Anxiety Treatment in Texas at Virtue Recovery Killeen
Anxiety can adversely affect a person’s personal and professional life. It can make managing daily activities such as work or school challenging and can impact relationships. Anxiety can also increase the likelihood of substance abuse and addiction. However, with proper treatment for anxiety, individuals can learn to manage their symptoms effectively, develop coping strategies, and live a fulfilling life. If you or a loved one is struggling with an anxiety disorder or addiction, contact Virtue Recovery Killeen today at 866.843.0545 to learn more about treatment for anxiety.

domain: health


Coimbatore: Three days after a TOI report threw light on the sorry state of the Tamil Nadu Agricultural University’s (Tnau
) botanical garden
, university officials on Monday revealed plans to renovate it under the smart city
“We are already working on developing the garden. We want to expand and transform it,” Tnau vice-chancellor K Ramasamy said.
Opening up about the restricted entry into the garden, the VC said that two university departments and a residence are located inside it.
“The restriction is only because many youngsters use the place to consume alcohol. Several girl students undertake studies there and this poses a huge risk to their safety,” he said.
A senior university official added that the garden was used only for academic purpose. “We restricted the entry as we do not have dedicated staff to maintain the garden. We also lack the resources. We had sent a proposal to the tourism department seeking Rs 5cr for its development,” he told TOI.
The university plans to set up a Japanese garden
, sunken garden, rock garden and a flowing cascade that will flow for 100m across the garden and be connected to several fountains, to beautify the place. “We plan to set up several types of garden to improve the green space. We will landscape the entire area in such a way that more indigenous species are planted. We can improve the flora and plant more tree species. Most of the trees were planted in the British era. Also, we will install several statues there. Currently, the garden has only Thiruvalluvar’s statue,” the official said.
The university also plans to set up a butterfly park
in the garden and will plant more species that attract butterflies. “Studies are being conducted on the various species of butterflies that visit the garden. Based on those studies, we will plant appropriate species,” the official revealed.
“If we get the required fund and workforce, we can completely transform the space. We want to attract more visitors to the place, which can be made more educative by adding name plates to various types of plant species,” the official added.
Meanwhile, city corporation officials said they are waiting for the fund required for garden renovation. “Though the VOC Park
Zoo and Vellalore Integrated Bus Stand are not parts of the area-based development (ABD area), we have sent proposals to the Central government to sanction funds for their development. Similarly, we would love to take up the botanical garden renovation work as well,” said an official in charge of the smart city project.
Tnau had earlier signed a memorandum of understanding with the city corporation for bioremedies to treat sewage entering city lakes.


TRADETUFF 1.5M ADJUSTABLE UNIVERSAL TRIPOD FOR WORK LIGHTS
This universal tripod stand for floodlight which enables one floodlight to be mounted on top for task lighting.
Ideal for job sites or locations where the need to adjust spot lighting is required.
- M8 Hand Wheel
- Height Adjustment (620m to 1.5m)
- Base locking Screw
- Cable Tidy
- Rubber Feet
- Single Light Fitting
- Easy to assemble, Easy fold tripod
Designed to work with:
- Tripod stand for LED Floodlights 10w, 20w, 30w, 50w, 80w, 100w or standard Halogen flood lamp
- Tuff-T Fold 3200 110V Foldable Work Light
- Tuff-T Fold 3200 240V Foldable Work Light
- Tuff-T Fold 1500R Foldable Rechargeable Work Light


Brooklyn Horror Film Festival Presents: FRIDAY THE 13TH
Friday, October 13 @ 4:00 pm
We are partnering with Brooklyn Horror Film Festival to host screenings of the first four Friday The 13th films on this very special, real-life Friday, the 13th of October. We’ll be serving drinks and food all evening, so stay for all four…if you dare!
GET TICKETS HERE
In the first installment in the famed horror franchise, Crystal Lake’s history of murder doesn’t deter counselors from setting up a summer camp in the woodsy area. Superstitious locals warn against it, but the fresh-faced young people — Jack (Kevin Bacon), Alice (Adrienne King), Bill (Harry Crosby), Marcie (Jeannine Taylor) and Ned (Mark Nelson) — pay little heed to the old-timers. Then they find themselves stalked by a brutal killer. As they’re slashed, shot and stabbed, the counselors struggle to stay alive against a merciless opponent.
Dir. Sean Cunningham. 1980. 95 min.