Microservices are a type of application architecture that builds cloud applications. Learn more about microservices, how microservice architecture works, its benefits, and applications.
In recent years, the rise of the internet and the ubiquity of mobile computing have made it necessary for application developers to design their applications focusing on a lightweight, self-contained component.
Developers need to deploy applications quickly and make changes to the application without a complete redeployment. This has led to a new development paradigm called “microservices,” where an application is broken into a suite of small, independent units that perform their respective functions and communicate via APIs.
Although independent units, the application may pull any of these microservices to work together and achieve the desired results.
What are microservices?
Microservices architecture, often called microservices, is an architectural approach or style of application development. It involves dividing large applications into smaller, functional units capable of functioning and communicating independently.
Developers have long waited for an alternative to monoliths to achieve the scalability, simplicity and flexibility needed to create highly sophisticated software applications.
Microservices architecture was developed to overcome monolithic architectural approaches to application development challenges and difficulties.
Monolithic architecture is like a large container holding all software components of an application: user interface, business layer, and data interface. This had several limitations, including inflexibility, lack of reliability, difficulty scaling, slow development, etc. It was to bypass these issues that microservices architecture was created.
Applications running on microservices architecture are deconstructed and separated into smaller units (microservices) that the client can access using an API gateway. These microservices are each independently deployable but can communicate with one another when necessary.
Breaking down an application into microservices allows for faster development, easier bug detection and resolution, smoother maintenance, flexibility, and higher availability and scalability.
How does Microservices Architecture work?
Microservices architecture focuses on classifying the otherwise large, bulky applications. Each microservice addresses an application’s particular aspect and function, such as logging, data search, and more. Multiple such microservices come together to form one efficient application.
This intuitive, functional division of an application offers several benefits. The client can use the user interface to generate requests. At the same time, one or more microservices are commissioned through the API gateway to perform the requested task. As a result, even larger complex problems that require a combination of microservices can be solved relatively easily.
Microservices systems facilitate each component service’s independent building, operation, scaling, and deployment. There is no sharing of the codes or functionality with other services. The use of well-defined APIs propagates communication between the program’s various components.
Depending on a specific issue, every service in the system is tailored to a unique set of skills. The services may further break down into more minor services if the developers provide additional code.
The other way around, Microservices are independently releasable services modeled around a business domain. A service encapsulates functionality and makes it accessible to other services via networks—you construct a more complex system from these building blocks.
One microservice might represent an inventory, another order management, and yet another shipping, but together they might constitute an entire eCommerce system. Microservices are an architecture choice that gives you many options for solving the problems you might face.
What are the key benefits of microservices architecture
About 87% of those who have adapted to the microservices architecture believe that it could soon become the favorite application of executives and project managers as it is now of developers. They are in tune with how the corporate owners intend to build, run and maintain their teams.
Using microservices architecture in application development can be highly beneficial. Below are some of its key benefits.
1. Requires less development effort to scale up
Due to the independent nature of microservices, smaller development teams can parallelly work on different components to update existing functionalities. This makes it significantly easier to identify hot services, scale independently from the rest of the application, and improve the application.
2. Provide better scalability
Microservices launch individual services independently, developed in different languages or technologies; all tech stacks are compatible, allowing DevOps to choose any of the most efficient tech stacks without fearing if they will work well together. These small services work on relatively less infrastructure than monolithic applications by choosing the precise scalability of selected components per their requirements, which is why scalability is better with microservices.
3. Can be deployed independently
Each microservice constituting an application needs to be a full stack. This enables microservices to be deployed independently at any point. Since the microservices are granular in nature, it’s easy for development teams to work on one microservice to fix errors and then redeploy it without redeploying the entire application.
Microservice architecture is agile and thus does not need a congressional act to modify the program by adding or changing a line of code or adding or eliminating features. The software offers to streamline business structures through resilience improvisation and fault separation.
4. Microservices offer improved fault isolation
In monolithic applications, the failure of even a small component of the overall application can make it inaccessible. In some cases, determining the error could also be tedious. With microservices, isolating the problem-causing component is easy since the entire application is divided into standalone, fully functional software units. If errors occur, other non-related units will still continue to function.
5. No dependence on one Tech Stack
A technology stack refers to a set of programming languages, databases, front-end and back-end tools, frameworks, and other components the developers use to build an application. With microservices, developers have the freedom to pick a technology stack that is best suited for one particular microservice and its functions. They have absolute control instead of opting for one standardized tech stack that encompasses all of an application’s functions.
What is microservices architecture used for?
Put simply; the microservices architecture makes app development quicker and more efficient. Agile deployment capabilities combined with the flexible application of different technologies drastically reduce the duration of the development cycle. The following are some of the most vital applications of microservices architecture.
1. Data processing
Microservices speed up data processing tasks since applications running on microservice architecture can handle more simultaneous requests. Larger amounts of information can be processed in less time, allowing faster and more efficient application performance.
2. Media content
Companies like Netflix and Amazon Prime Video handle billions of API requests daily. Services such as OTT platforms offering users massive media content will benefit from deploying a microservices architecture. Microservices will ensure that the plethora of requests for different subdomains worldwide is processed without delays or errors.
3. Website migration
Website migration involves a substantial change and redevelopment of a website’s major areas, such as its domain, structure, user interface, etc. Using microservices will help you avoid business-damaging downtime and ensure your migration plans execute smoothly without any hassles.
4. Transactions and invoices
Microservices are perfect for applications handling high payments and transaction volumes and generating invoices for the same. The failure of an application to process payments can cause huge losses for companies. With the help of microservices, the transaction functionality can be made more robust without changing the rest of the application.
Building a microservices architecture requires a mix of tools and processes to perform the core building tasks and support the overall framework. Some of these tools are listed below.
1. Operating system
Arguably, the most basic tool required to build an application is an operating system (OS). One such operating system allows great flexibility in development and uses in Linux. It offers a largely self-contained environment for executing program codes and a series of options for large and small applications in terms of security, storage, and networking.
2. Programming languages
One of the benefits of using a microservices architecture is that you can use a variety of programming languages across applications for different services. Different programming languages have different utilities deployed based on the nature of the microservice.
3. API management and testing tools
The various services need to communicate when building an application using a microservices architecture. This is accomplished using application programming interfaces (APIs). For APIs to work optimally and desirably, they need to be constantly monitored, managed and tested, and API management and testing tools are essential for this.
4. Messaging tools
Messaging tools enable microservices to communicate both internally and externally. Rabbit MQ and Apache Kafka are examples of messaging tools deployed as part of a microservice system.
Toolkits in a microservices architecture are tools used to build and develop applications. Different toolkits are available to developers, and these kits fulfill different purposes. Fabric8 and Seneca are some examples of microservices toolkits.
6. Architectural frameworks
Microservices architectural frameworks offer convenient solutions for application development and usually contain a library of code and tools to help configure and deploy an application.
7. Orchestration tools
A container is a set of executables, codes, libraries, and files necessary to run a microservice. Container orchestration tools provide a framework to manage and optimize containers within microservices architecture systems.
8. Monitoring tools
Once a microservices application is up and running, you must constantly monitor it to ensure everything is working smoothly and as intended. Monitoring tools help developers stay on top of the application’s work and avoid potential bugs or glitches.
9. Serverless tools
Serverless tools further add flexibility and mobility to the various microservices within an application by eliminating server dependency. This helps in the easier rationalization and division of application tasks.
Challenges associated with microservices architecture
The microservices architecture comes with its fair share of challenges, from deployment to operation and maintenance. Some of these challenges are discussed below.
1. Inter-service communication
Although microservices can exist and function independently, they often need to interact and communicate with other microservices to fulfill certain demands or tasks. This necessitates maintaining a fully functional API serving as a communication channel between multiple services constituting the application.
2. Distributed logging
When different and independently operating microservices are deployed as part of an application, each of these services has a distinct logging mechanism. This results in large volumes of distributed log data that are unstructured and difficult to organize and maintain.
3. Transaction spanning
Distributed transactions refer to transactions that require the deployment and proper functioning of a series of microservices to run. This means that a transaction spans multiple microservices and databases and a small failure in just one will result in a transaction failure.
4. Cyclic dependencies between services
A cyclic dependency in a microservices architecture refers to the codependency of two or more application services or modules. Cyclic dependencies can make it difficult to scale the application or independently deploy and manage microservices. They’re also infamous for making code more complex to maintain. If they persist for long, decoupling becomes close to impossible.
Examples of companies that adopted microservices architecture
With recent advances in cloud technology, many big brands have now advocated moving from a monolithic to a microservices architecture for better functionality. Let’s look at two such companies that have vastly improved their business by leveraging microservices.
If you look at Amazon’s retail website in 2001, it essentially worked as a single, monolithic application. The lack of application flexibility made developers struggle while untangling dependencies when upgrading or scaling the services. As a result, Amazon struggled to meet the needs of its rapidly growing customer base.
To solve this issue, the Amazon development team split the large, monolithic application into smaller, independent services managed and handled by separate developer teams. Amazon’s efforts eventually led to the creation of a highly decoupled, service-oriented architecture that we now refer to as microservices architecture. These changes made Amazon overcome all of its scalability and service outage problems and hit a market cap of $1.7 million. The image below is a visual representation of the microservices architecture deployed by Amazon in 2008.
Netflix started its movie streaming business in 2007. Within just a year, it started facing severe scalability issues and service outages. In 2008, Netflix failed to ship DVDs to customers for three consecutive days. This is when they decided to switch to a distributed cloud system with Amazon Web Services (AWS) as the cloud provider.
Later in 2009, Netflix began moving its application architecture from monolithic to microservices, and this process was finally completed in 2012.
This move to a microservices architecture enabled Netflix to overcome its scalability challenges and offer its services to millions around the world. In 2015, Netflix’s API gateway successfully processed 2 billion API requests daily – thanks to a group of over 500 cloud-hosted microservices. The cost of streaming was also reduced, which allowed Netflix to make significant financial gains. Netflix’s application consisted of over 700 microservices by 2017, and the streaming service has grown exponentially over the past decade.
Switch from monolithic to microservices architecture
Microservices architecture is the most accepted and reliable approach to developing cloud applications today. It’s highly backed due to the various advantages it brings to tech development teams in the form of shorter development times, improved flexibility, and greater reliability.
It is also unnecessary for a business with existing applications to build the microservices architecture from scratch. Several options are now available that allow converting web applications from monolithic to microservices.
If you are looking for ways to scale your organization’s tech capabilities and overcome outages, poor performance, and geographic challenges, check out our solutions.


Michelle Obama has joined the popular social media app Snapchat.
The US first lady shared a selfie with her first post on the messaging service, before announcing she will appear on Carpool Karaoke with James Corden.
A spokeswoman for Mrs Obama said her Snapchat followers will see images from her upcoming trip to Liberia, Morocco and Spain to promote education for girls.
Mrs Obama's teenage daughters Malia and Sasha will accompany her on the trip, while actresses Meryl Streep and Freida Pinto will also make guest appearances.
The first lady will also share Snapchat images of the White House kitchen garden and of Obama family's dogs Bo and Sunny, her spokeswoman said.
Mrs Obama, 52, is an active social media user with some 4.58 million followers on Twitter and five million on the photo-sharing app Instagram.
She is following in the footsteps of Adele, Elton John, Justin Bieber and Stevie Wonder, who have all taken part in Carpool Karaoke on Corden's US chat show The Late Late Show. The date the segment will be aired has not been announced.


This video is from Mina Leon’s long awaited LP “Running Red Lights”. The ST/MiC produced and Tef Wesley featured ode to the thing we all love most is one of my favorite songs from the album. I was asked to be in this video but per usual random bullshit prevented that from happening. Don’t sleep on this jawn…
DON’T SLEEP: Bloggerhouse x Producers I Know x Timeless Daimyo Music presents ST/MiC “In The Pocket” [FREE ALBUM]
It was about a year ago that our boy from Virginia, ST/MiC (who’s also a world renowned well respected emcee, DJ/remixer/producer/beatmaker/engineer as well) told us to he copped an INTUA.net iPhone app called BeatMaker and a synth app called Noise.io then proceeded to make an entire project using them. We heard a few of the original rough tracks on our first ever archived edition of the Scrunchface Show and Eric & I both went nuts over them. Whenever that project was done, we were definitely going to feature it on Bloggerhouse.
Several months later, ST/MiC sent me 9 instrumental tracks that were going to serve as the skeleton of “In The Pocket” and asked me what I thought of them. I told him that some tracks he should get his rappity rappin’ ass friends to spit on and others he should allow to just rock on their own. I also suggested what kind of emcees should rock and on what tracks. We had a follow up phone conversation the next day and we agreed. MiC went back and recruited some emcees over his production…done all on an iPod Touch.
In early 2011, ST/MiC sent me an early WAV version of “In The Pocket” without cover art featuring scratches, bars and hooks from Moka Only, Jazz Addixx, Has-Lo, Praverb The Wyse, Primo The Cinematic & Waterloo. MiC decided to include all the instrumentals as well. Good call. A month later, MiC sent me a tagged, mastered mp3 version of “In The Pocket” with some gorgeous cover art. Given the recent success of the Producers I Know sponsored instrumental or producer based releases I knew that I’d be dropping this on both Bloggerhouse and Producers I Know. I can’t wait for you all to hear it as well.
In conclusion, the wait is over. I’ve done all the write ups I needed to. We’ve even played some of the beats on The Scrunchface Show. You’ve heard the single. Now hear the completed album. 15 total tracks, 6 with vocals from Jazz Addixx, Praverb The Wyse, Moka Only, Primo The Cinematic, Has-Lo & Waterloo. All 6 vocal tracks have instrumentals provided plus bonus instrumentals “Sumr” & “No Subshine”. I’m proud to finally present to you all ST/MiC’s “In The Pocket”. Enjoy:


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This large, wonderful book published by Al Khamsa Inc, is loaded with history, info, and photos of Al Khamsa horses. A treasure trove of information.
Arabia & The Tribes
Welcome to Al Khamsa
Europa Foundation Stock
671 pages, large hard cover book, printed on glossy paper, binding strong, pages clean and unmarked, copyright 1993, very good condition

domain: hobby


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People who use culture in this way tend not to use it in the plural. Impementing a project management approach often involves dramatic changes in the relationships of authority and responsibility. He viewed job tasks as a bunch of components that could be analyzed and broken down into small parts. He believed that managers could achieve more if they start perceiving their employees as self-energized, committed, responsible and creative beings. An amoral corporation pursues profit at any cost.
Several understandings of how cultures change come from Anthropology. He took an external perspective of organizational behavior. In his classic writing in 1931, Human Problems of an Industrial Civilization, he advised managers to deal with emotional needs of employees at work. An important element of using mental models is the need to balance inquiry and advocacy. Several researchers have hypothesized that organizational growth is beneficial only up to a point Hedberg, Nystrom, and Starbuck, 1976; Meyer, 1977; Perrow, 1979. The Way We Never Were: American Families and the Nostalgia Trap. What we may devour here in the U.
Organizational activities often involve attempts to focus on a specific market niche in which the organization might have a competitive advantage. The term was coined by William Graham Sumner, a social evolutionist and professor of Political and Social Science at Yale University. It became clear that the traditional S-curve model was incomplete and did not address the issues of declining organizations. The first mention of analyzing work was with Frederick Winslow Taylor 1856-1915. This is despite the fact that the U. Defining Organizational Culture Organizational culture works a lot like this.
The role of human resource management in such a context is to inculcate and reinforce such behavioral patterns in the workforce. Is the world around us truly that simple? Community Gozdz 1992 believes that learning organizations are centered around the concept of community. Max Weber 1947 expanded on Taylor's theories, and stressed the need to reduce diversity and ambiguity in organizations. Relationship : The index measures the extent to which the dominant values are assertiveness, money and things achievement , not caring for others or for quality of life. Starting in the 1980s, cultural explanations of organizations and change became an important part of study.
Distinction: A Social Critique of the Judgment of Taste, trans. Where the entrepreneurial stage involves a series of trial and error endeavors, the next stage is the standardization of rules that define how the organizational system operates and interacts with the environment. Image Credit: The Critical Perspective of Human Resource Management The critical perspective of human resource management is a reaction against the normative perception. It does not imply normalcy for oneself, nor for one's society. This bifurcation is necessary because the entrepreneurial environment of inventing business is incompatible with the controlling environment of the core business. Interest grew in theory and methods native to the sciences, including , the study of and.
It may also be referred to as organizational studies or organizational science. Management must communicate a clear message of the organization's situation and instill confidence in its ability to meet the crisis. The Goodwin Company, an organization specializing in contract packaging of household and automotive cleaning products, and Patagonia, a global brand supplying high-quality outdoor clothing and equipment, provide examples of this phenomenon. The third stage involves the implementation of a downsizing program. Denison considered that organizational culture is entrenched in a set of basic assumptions, values and beliefs about employees, management, customers, shareholders, suppliers and others.
Warwick 1975 reported that the growth in the U. Functions of Organizational Culture It is tempting to emphasize the significance of organizational cultures for performance, growth and success. This focused on , , and the actualization of the goals of individuals within organizations. It is viewed as social interaction result, as is a root metaphor for conceptualizing organizations Smircich, 1983. This may result in the loss of effectiveness of a company or an individual in terms of international competitiveness.
When individuals have to negotiate meaning publicly, it makes it much easier for the sociologist to tease out culture. The first phase in organizational growth is the entrepreneurial stage. A counterculture is a subculture with the addition that some of its beliefs, values, or norms challenge or even contradict those of the main culture of which it is part. This approach works under the assumption that what is good for the organization is also good for the employee. The shortcomings of classical organization theory quickly became apparent. Chandler 1962 studied four large United States corporations and proposed that an organization would naturally evolve to meet the needs of its strategy -- that form follows function. The second is one of communication.

domain: sociology


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The incredible, bestselling memoir of survival, hope and empowerment
The stunning sequel to the worldwide phenomenon Me Before You.
The enthralling new novel from the 10-million-copy, No. 1 bestselling author.
A collection of eleven unmissable short stories from the Number One internationally bestselling author.
Lou Clark knows lots of things. She knows how many footsteps there are between the bus stop and home. She knows she likes working in The Buttered Bun tea shop and she knows she might not love her boyfriend Patrick.
Over the course of five decades, founding editor of Rolling Stone Jann Wenner has put an indelible stamp on American culture. A nuanced portrait of a man who helped define a generation, and provides an explosive chronicle of an era.
An absolute classic coming-of-age novel from the 1940s, with an irresistible narrator, which fans of contemporary writers such as Meg Rosoff, Rainbow Rowell or E Lockhart will love. Part of the Originals - Penguin's very best modern classics for young adults.
THE FOURTEENTH CLIFFEHAVEN NOVEL BY SUNDAY TIMES BESTSELLING AUTHOR ELLIE DEAN
One of 15 limited edition Vintage Future Classics published to celebrate Vintage's 15th birthday. The 15 titles were voted for by reading groups all over the UK as being books that would still be read in 100 years time.
A YEAR IN THE COUNTRY. A YEAR TO FALL IN LOVE. The BRAND NEW deliciously romantic novel from the Sunday Times Number One Bestselling Author of A Summer At Sea and A Secret Garden.
Can the tide of war heal her broken heart? THE BRAND NEW THIRTEENTH CLIFFEHAVEN NOVEL BY SUNDAY TIMES BESTSELLING AUTHOR ELLIE DEAN
A gripping love story set during Kenya's Mau Mau uprising.
A laugh-out-loud funny novel from one of women's fiction's royalty about what happens when the life you've dreamed of is almost within reach . . .
A riveting historical art mystery for fans of Chasing Vermeer and The Westing Game, set in the Roaring Twenties!
Tom has just 20 seconds to save the world. But which world will he choose?
Delve inside this Christmas stocking, a present from the Number One Sunday Times Bestselling author Katie Fforde
A gripping WW2 saga perfect for fans of Daisy Styles's The Bomb Girls and Nancy Revell's Shipyard Girls
I want to make my husband fall back in love with me, so that when I tell him to get out of my life he'll care. I want it to hurt.
A special edition of E L James’s #1 New York Times bestselling novel, Fifty Shades Darker, that includes her own photos and caption commentary from the making of the film—and an excerpt from her forthcoming book, Fifty Shades Darker, As Told by Christian Grey.
MORE THAN 100 MILLION COPIES SOLD WORLD WIDE. Soon to be a major movie starring Jamie Dornan and Dakota Johnson, directed by Sam Taylor-Johnson.
The first in the sexy, shocking and compulsively readable Mad, Bad and Dangerous to Know trilogy.
Romance, humour and happy-ever-after endings. The deliciously romantic novel from the No. 1 Sunday Times bestselling author of A Vintage Wedding.
Submission is the highly-anticipated new novel from the internationally bestselling French writer Michel Houellebecq
The acclaimed, bestselling manga about a girl who can’t hear and the boy who bullied her, from start to finish, in a premium, collectible box set. Includes all seven volumes, plus an exclusive, double-sided 10-by-15-inch poster and a replica of Shoko’s communication notebook.

domain: entertainment


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Dear specialists of profile medical associations!
We invite you to participate in the discussion and making adjustments to Draft Regulation on development/revision of clinical protocols at the following link.
The discussion of the regulation will continue until April 24, 2017
APPROVED CLINICAL PROTOCOLS
RSE on REM "Republican Center for Health Development" of the Ministry of Healthof the Republic of Kazakhstan (hereinafter - RSE on REM "RCHD") informs the following.
On April 4, 2016, a memorandum of cooperation was signed between RSE on REM "RCHD" and LLP "Accounting and Management", which aims to promote the development of e-health in the Republic of Kazakhstan (hereinafter - RK), as well as providinghigh-quality information service in the field of e-health RK "Electronic base of clinical protocols (hereinafter – CP) MHRK for further informing practical health care professionals about the possibility of quick and relatively simple updating of CP.
In accordance with Subparagraph 59-1, Paragraph 1, Article 1 of the Code of the Republic of Kazakhstan "On the Health of the People and the Healthcare System" (hereinafter - the Code), the clinical protocol is a document that establishes general requirements for the provision of medical care to a patient in a particular disease or clinical situation.
According to paragraph 3 of Article 33 of the Code, health care providers are guided by clinical protocols when providing medical assistance.
The clinical protocol is not a normative legal act and is of an advisory nature.

domain: medical


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After the Environmental Protection Agency (EPA) dropped its investigation of five coal-fired power plants owned by Allegheny Energy Inc., New York Attorney General Eliot Spitzer announced May 20 that his state, along with Connecticut, New Jersey and Pennsylvania, will sue the company.
In a letter addressed to the company, the states charge that Allegheny modified the power plants in violation of the Prevention of Significant Deterioration provisions of the Clean Air Act. As a result, the plants have allegedly emitted excess amount of nitrogen oxides and sulfur dioxide.
Prevailing winds carry the pollutants to downwind states, causing smog and acid rain and provoking a variety of respiratory diseases.
"Air pollution from coal-fired power plants is a serious threat to New York's environment and public health," declared Spitzer in a statement. "It is disturbing that the federal government is no longer enforcing the Clean Air Act… New York and its partners will act if the federal government is unwilling to do so."
A "notice of intent to sue letter" is required under the Clean Air Act, as the company alleged to be in violation of the laws must be given 60 days to negotiate a settlement before the lawsuit can be filed
Allegheny Energy Inc. denies that its subsidiaries violated provisions of the Clean Air Act. "We believe that we have been and continue to be in compliance with all existing state and federal environmental laws, including the matters described in the notice," said Paul J. Evanson, chairman, president and CEO, in a prepared statement dated May 20. "We are always mindful of our responsibilities as an environmental steward in the operation of our power plants. Accordingly, we welcome the opportunity to meet with these states to amicably resolve these matters."
The alleged failure of Allegheny to comply with the Clean Air Act after modifying its plants is related to the controversial New Source Review (NSR) regulation of the law. The Bush administration's revised NSR proposal, which is particularly favored by coal-fired power plants, is tied up in litigation. Meanwhile the administration has said it will continue to enforce the existing rule, but environmental groups and some states dispute this.
"We are continuing to enforce the NSR program," said EPA press secretary Cynthia Bergman in a statement. "Because of limited enforcement resources, we will continue to set priorities for the cases that should be pursued first."
Bergman contended that EPA has proposed a regulation that will require power plants to reduce emissions by 70 percent.

domain: news


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Middlemarch Mates #9
by: Shelley Munro
Released: July 2010
Ambar Patel has always wanted her freedom to do whatever she wants with her life so her relationship with Jake is perfect he is perfectly content with the way things are no push for commitment. They are soon to discover that their lives are about to change.
Hari Daya arrives with the sole purpose of mating with Ambar. Regardless he has never met her but like other female tiger shifters she should jump for joy at being his mate. What he was not expecting was getting the door slammed in his face and that his soon to be mate already has a lover in her life, a lover that he finds himself drawn to as well.
Jake Quinn who has no knowledge of the shifters in his own town including his lover Ambar needs money so when Hari comes into town he offers to rent him a room at his place. What Jake is unaware of is that Hari is there for Ambar. Even more confusing to him is the attraction he feels towards Hari? He has never been drawn to a man before why now?
As they all try to figure out what they are feeling towards the others as well as the battle Ambar is having with herself to not mate with either one of the men even though the overwhelming need to bite and mark both men is strong she is determined to keep her plans to travel and retain her independence.
As soon as I started reading TIGER BY THE TAIL I knew I would not be able to put it down. I was hooked from the first page. The chemistry between Ambar, Jake and Hari is intense and somewhat humorous. Ambar is so strong and set in her ways that it takes a lot of work for Hari to convince her that what she really wants is a mate. One of the nice things about this series is that Shelley Munro has made sure you can read book nine and not even realize you are reading part of a series. You will meet some of the characters from previous books as well as future ones I am sure but they are defiantly stand alone books but if you are like me you will want to go back and read all the others.
Annette gives this book:

domain: literature


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|Title||A cohort study of the impact of tooth loss and periodontal disease on respiratory events among COPD subjects: modulatory role of systemic biomarkers of inflammation.|
|Publication Type||Journal Article|
|Year of Publication||2013|
|Authors||Barros SP, Suruki R, Loewy ZG, Beck JD|
|Secondary Authors||Offenbacher S|
|Keywords||Biomarkers, Cohort Studies, Female, Humans, Inflammation, Interleukin-6, Male, Middle Aged, Mouth, Edentulous, Periodontal Diseases, Proportional Hazards Models, Pulmonary Disease, Chronic Obstructive, Tooth Loss|
BACKGROUND: In COPD patients, fatal and non-fatal respiratory-related events are influenced by age, severity of respiratory disease, and comorbidities.
OBJECTIVES: Analyze the effects of edentulism, periodontal disease and systemic biomarkers of inflammation on the occurrence of serious fatal and non-fatal respiratory-related events among subjects with COPD.
METHODS: Cases were identified from Dental Atherosclerosis Risk in Communities study. Edentulism was defined as study participants without any natural teeth or implants. Participants with one or more natural teeth (comprising 11,378 subjects) were studied as dentate subjects. Periodontal disease status among dentate individuals was determined using the consensus definitions published by the joint Center for Disease Control/American Association of Periodontology working group). Adjusted Hazard Models are developed to evaluate the relationship between edentulism/periodontal disease and COPD Related Events. Models were then stratified by GOLD Stage I, II and III/IV. Serum biomarkers were also evaluated to explore the effect of systemic inflammation.
RESULTS: A statistically significant association was found between oral health status and COPD-related events, even adjusting for conditions such as hypertension, smoking and diabetes. Edentulous individuals who had been diagnosed with COPD had a higher incidence and were at greater risk of having a COPD related event (hospitalization and death) than individuals who had teeth and whose mouths had healthy periodontal status. However, being edentulous did not convey excess risk for COPD-related events for those study participants who were classified as GOLD III/IV at baseline. Finally, we showed that individuals who had levels of serum IL-6 in the highest two quartiles were at even higher risk for COPD-related events.
CONCLUSIONS: These findings suggest that the risk for COPD-related events after adjusting for potential confounders may be attributable to both edentulism and elevated serum IL-6 levels.
|Alternate Journal||PLoS One|
|PubMed Central ID||PMC3738507|


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A diagnosis of cancer bears a tremendous psychological impact on a patient’s psyche. It is common for individuals diagnosed with cancer to develop anger, anxiety and/or depression during the first year of the disease. However, the moderate rate of major depressive disorder and the high rate of minor depressive disorder are accompanied by sub-threshold forms of depression that are at risk to be under-recognised and untreated.
cancer, psycho-oncology, mental stress, physical stress, depression, aging
Recent research studies have identified extreme suppression of anger as the most common psychological trait amongst 160 elderly breast cancer patients . Other studies have confirmed that further to extreme anger, suppression, repression or restraint of anger are emotions generally exhibited by breast cancer patients . Epidemiological studies have reported that participation in psychological support groups is associated with better health outcomes for these patients, calling for an integration of such a modality in cancer management and treatment . With such a consistent evidence pointing to a link between emotional distress and chronic disease, the question asked is whether suppressed anger could also be identified as an indicative factor in the progression of the disease after diagnosis.
A complete eradication of a malignant tumour is not always achieved even after the completion of a conventional aggressive treatment. In many instances, interventions of complementary and alternative medicine have been shown to achieve excellent results and to work well in conjunction with conventional approaches, as tumours increasingly meet the definition of chronic diseases . Treatment protocols of some cancers like breast, prostate, and colon cancer can last for months; individuals on certain oral chemotherapeutic regimens particularly for breast cancer and some forms of leukaemia often require chemotherapeutic interventions for years. Even after the completion of a treatment protocol, cancer survivors generally need to receive ongoing physical care from multiple specialists in order to manage the long-term residue of the illness and its treatment .
In addition to dealing with severe concerns brought about by their diagnosis, cancer patients and their families must cope with the stresses caused by physically demanding chemotherapy and radiation therapy treatments, which often result in physical impairment, disability, fatigue, and pain . Physical debilitation further contributes to emotional distress, depression and anxiety, inevitably leading to substantial social problems, such as the inability to work and sudden loss of income. Furthermore, the presence of pre-existing psychological and social stressors often caused by a weak or absent social supports and/or lack of health insurance has been shown to contribute to cancer patients’ emotional distress, with physical, psychological, and social stressors resulting from and contributing to each other .
Regardless of the type of cancer and the chosen conventional treatment, the physical and developmental age of cancer patients have also demonstrated to be a contributing factor for their psychological health . According to data distributed by the American National Cancer Institute in 2013, approximately 60 percent of individuals who were diagnosed with cancer are aged 65 or older, 39 percent are young and middle-aged adults, and 1 percent is aged 19 or younger .
There is evidence showing that treatment care and aging are variable indicators. Health and well-being, social circumstances, living arrangements, and age-related changes, resulting in diminished psychological and physical functioning, vary by individual and are not determined by chronological age . However, older adults, when compared to a younger population, are more likely to present with one or more pre-existing chronic diseases as well as increased functional impairment and disability, both of which can only compound on the stresses imposed by a diagnosis of cancer . Moreover evidence indicates that older cancer patients are at greater risk of displaying reduced health-related decision making abilities .
Compared to healthy people, at the time of diagnosis, adults with or without a history of cancer, more frequently report a fair or poor state of health (30 percent); other existing chronic medical conditions (42 percent); one or more physical limitations in performing activities of daily living (11 percent); other functional disabilities (58 percent), and, among those under the age of 65, it is commonly recorded a chronic inability to work because of an existing health condition (17 percent) . Research studies have reported that cancer survivors who experience limitations in performing physical daily activities, indicated cancer to be the causative factor of their poor quality of life. Likewise, the incidence of chronic diseases amongst cancer survivors has been shown a much higher incidence when compared to those without a history of the illness. Data collected between 1998 to 200 by the National Health Interview Survey (NHIS) in United States indicate that there is a strong like between a history of cancer and the onset of permanent disability. Further research studies have demonstrated the connection between cancer survivors and the development of cardiovascular disease. These studies have also been shown that when a history of cancer and chronic disease coexist, there is a 10 fold higher risk for disability to occur . Survivors of childhood cancers have been found to suffer with a higher incidence of chronic diseases in their early or middle adult years. A large retrospective study conducted on over 10,000 adults cancer survivors has produced some alarming statistics: 62% of individuals between the ages of 18 and 48 who had been diagnosed with cancer before the age of 21, had developed at least one chronic disease, with 27% of them being affected by a sever or life-threatening condition such as kidney failure and congestive heart failure. Although on average chronic health conditions have been estimated to appear about 17 years after the cancer diagnosis, even after 30 years from a previous cancer diagnosis, three-fourth of individuals with a previous history of cancer have been shown to suffer with significant chronic illnesses.
With the exception of a review conducted by Perry et al. (2009), none of the above research studies have reported estimates of the incidence of mental health problems affecting individual with a previous history of cancer .
Cognitive impairment is also commonly detected amongst older cancer patients. Cancer and the therapeutic modalities used to treat cancer have been associated with alterations in patients' cognitive, emotional, and neurologic functioning. It is widely accepted that disease involving the central nervous system (CNS) and treatments targeting it (e.g., radiotherapy) may have adverse effects on cognitive functioning. Studies conducted on breast cancer patients treated with conventional chemotherapy revealed a consistent decline in global cognitive functions, short-term memory, language skills (word-finding ability) and spatial ability.Other research findings have pointed out that verbal memory and other cognitive functions appear to be affected in cancer survivors in different degrees. For example, adults treated for lung, lymphoma and colorectal cancers display varying degrees of cognitive functional impairment depending on the treatment received . Cross-sectional and retrospective case-control studies strongly suggest an association of depression symptoms with cognitive impairment .
Fatigue at rest is another commonly detected symptoms reported by the majority of cancer patients to be the most significant factor affecting their quality of life. The estimated rate of fatigue displayed by cancer patients vary significantly depending on the method of treatment. For example, the level of fatigue expressed by breast cancer patients prior to the start of chemotherapy was calculated to be 4% and to increase dramatically to 91% for those patients who had undergone surgery and chemotherapy . Despite the widespread occurrence of cancer-related fatigue, a 2002 review conducted by the Agency for Healthcare Research and Quality (AHRQ) in United States revealed that studies on the mechanism of cancer-related fatigue and treatment options were very limited . Fatigue is reported by cancer patients as negatively impacting their physical and mental capacities . A recent cohort study has demonstrated that almost half of the total number of cancer patients who participated in the study reported fatigue to be one of the most distressing symptoms they experienced .
Quality of life of cancer patients is significantly impacted by pain. An estimated one-third to one-half of all cancer patients undergoing conventional treatment suffer with pain which is often not entirely eliminated by analgesics and other therapies. Research has been shown that pain continues to negatively impact cancer patients even when there is no longer any sign of the disease and it is considered to be a contributing factor to fatigue as well as diminished physical and mental functions .
Pain, fatigue and physical impairment negatively impact cancer patients in their ability to conduct daily routine activities. Activities such as preparing meals, bathing, using the restroom, shopping, paying bills and using transportation have been found to be limited for most adults cancer patients. Compared with age-matched individuals, older patients with a history of cancer are more likely to require physical and psychological support to help them coping with various activities of daily living . Research studies conducted between 1998 and 2000 have demonstrated that individuals with a prior history of cancer and without co-existing chronic illness, reported limitations in their ability to perform daily activities .
The emotional distress caused by a diagnosis of cancer and its conventional treatment; the experience of pain, fatigue and diminished cognitive function contribute to either create or worsen pre-existing psychological distress for the patients, their families and other caregivers .
The incidence of psychological distress has been shown to vary considerably depending on type of cancer, time since diagnosis, amount of pain, degree of physical impairment and prognosis. A comprehensive study conducted on 4,500 older adult cancer patients has indicated that the rate of significant psychological distress felt by individuals varied from 29% to 43% depending on the type of cancer being diagnosed  and the degree of depression, and anxiety displayed . Population studies have detected symptoms of post-traumatic stress disorder (PTSD) and post-traumatic stress symptoms (PTSS) to characterise older adults cancer patients . According to the American Psychiatric Association’s Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR), 2000, a diagnosis of either PTSD or PTSS applies to those individuals who have experienced or perceived an event to be life-threatening. Those individuals diagnosed with cancer who do not develop a mental health condition, have been found to experience various forms of psychological distress, including guilt, anger, confusion, fear and sadness . Furthermore, anxiety, concerns about body image and (lack of) communication with family members, changes in sexual function and a general heightened sense of vulnerability are commonly felt by cancer patients. Moreover, cancer patients often face spiritual and existential issues involving their faith and the meaning of end of life. In response to these and other stresses, cancer patients often report feelings of isolation, anger and diminished self-esteem .
A diagnosis of cancer has been shown to profoundly affect the patient’s family members. A meta–analysis conducted on the psychological distress recorded by both patients and their primary caregivers, has shown that the psychological distress experienced by these individuals is as severe as that demonstrated by the individual diagnosed with cancer . Moreover, research studies on husbands/partners/daughters and friends of women diagnosed with breast cancer, have documented that the degree of depression and anxiety expressed by the patient was reflected in these individuals in a bidirectional way . Likewise, family members expressing a positive attitude have been shown to beneficially improve the mental health status of cancer patients.
Predominantly family members but also friends often provide substantial amounts of emotional and logistical support to cancer patients . The estimated value of their non-reimbursed care and support has been shown to exceed $1 billion annually . Further, when cancer patients experience acute or long-term inability to care for themselves or to carry out their roles in the family, family members often step in to take up these roles. Taking on these responsibilities requires considerable adaptation and re-adaptation as the course of the disease changes.
The emotional stress experienced by older caregivers is often worsened by the morbidity accompanying their own aging . Older caregivers who provide support to their spouse and report caregiving strain are 63 percent more likely to die within 4 years than those who do not provide care to their spouse or who provide care but report no significant strain . High stress levels affecting family caregivers have been shown to interfere with their ability to provide the emotional or logistical support patients needs. Due to the demands brought about by the necessary adaptation and demands of the cancer patient, family members are sometimes considered “second-order patients” . The disruption of simple daily activities for those individuals who have mastered a great degree of self-sufficiency is particularly difficult to cope with. The effects of conventional cancer treatment negatively impact the self-esteem of the individual diagnosed with the disease because it requires to temporarily or permanently give up known skills and activities. Consequently, particularly older cancer patients are psychologically and emotionally affected when they suddenly experience developmental delays, regression, or inability to perform social roles, as well as limitations in grand parenting abilities and the inability to act as caregiver to others in their family.
Studies have shown that children diagnosed with cancer and who are hospitalised during periods of critical growth are at higher risk of displaying loss of developmental steps,  whilst adolescent have been shown to suffer a reduction in independence and critical social skills. Furthermore, physical changes resulting from conventional cancer treatment, has demonstrated to negatively impact on endocrine function, with a general delay in puberty and impaired mental development. Adolescents and older cancer survivors have been shown to endure significant difficulties in planning for the future and in establishing educational and career aspirations. Because of their illness, adolescents and young adults may gain less work experience and as a result, they may be disadvantaged in the labour market. Their status can be further exacerbated if their illness or treatment has resulted in disfigurement or impediments requiring special consideration in the workplace.
Fear of social stigma and discrimination following a cancer diagnosis and treatment has been documented in some studies. School-age children may return to their social group displaying physical changes such as amputations, loss of hair and/or weight gain, which may result in exclusion or abandonment. These children have also been found lacking mental abilities when compared to their peers, resulting in another obstacle in re-entering social relationships .
A survey study conducted in United Stated in 2003 has shown that nearly one in five (12.3 million) individuals diagnosed with cancer belonged to a low socio-economic status preventing them to pay medical bills . Furthermore, a vast majority of these individuals have been shown to be unable to pay rent or mortgage, transportation and food as a consequence of cost of medical bills . Data published by the National Survey of U.S. Households Affected by Cancer in 2006, has revealed that one in four families in which a member had been diagnosed with cancer had used most of their savings to pay medical bills. Over 7 percent of the surveyed population was forced to borrowed money, and 3 percent had declared bankruptcy. Eight percent of cancer patients had delayed or did not receive care because of the financial cost involved in their care. In 2001, bankruptcy filed by individuals indicated that the cost of medical bills associated with conventional cancer treatment, to be one of the critical factors for their financial problems. Not surprisingly, members of the American Society of Clinical Oncology (ASCO), the Oncology Nursing Society (ONS), and the Association of Oncology Social Work (AOSW) have reported psychological distress due to financial concerns as a frequent subject of patient inquiries . Most of the financial costs stem from rising prices of conventional medical treatments, expensive drugs and other medical supplies, which are often not covered by health insurances. Moreover, cancer patients undergoing conventional therapies often suffer with prolonged periods of unemployment and net loss of income. In 2006, the Institute of Medicine (IOM) published a report titled “From Cancer Patient to Cancer Survivor: Lost in Translation”, that demonstrated that the vast majority of cancer patients  stopped working or experienced a change in employment (reduction in work hours, interruption of work, change in place of employment) immediately after being diagnosed with cancer. Data from NHIS between 1998 and 2000, have demonstrated that 17 percent of individuals with a history of cancer reported being unable to work, compared with 5 percent of those without such a history . A retrospective cohort study carried out in five medical centres in United States and conducted on 1,435 cancer survivors aged 25–62 who were employed at the time of their diagnosis, had resigned from their employment while undergoing cancer treatment. Although 84 percent of cancer patients returned to work within the 5 years after diagnosis, with 73 percent within the first 12 month after diagnosis, a significant minority (16 percent) composed by older patients chose not to return to work. Of those who decided to return to work, a minority had chosen to stop working due to health concerns and lack of coping abilities within the three years following treatment. Individuals diagnosed with head and neck cancers, lymphatic and stage IV blood cancers as well as cancers of the central nervous system have been shown to record the highest unemployment rates . The changes in employment patterns are reflective of either a desire for shifting priorities or of a need for seclusion. However, many cancer patients have reported that their employability was severely impacted by their diminished ability physical and mental functions resulting from conventional cancer diagnosis and treatment.
The physical and psychological problems described above can be exacerbated by, or produce significant new social problems. Financial stress resulting from low income, the cost of health care, or a lack of health insurance, as well as reduced employment and income, can result in substantial stress. While the fundamental resolution of such social problems is beyond the abilities of health care providers, the evidence described shows why attention to these problems is an integral part of good-quality health care and how they should be addressed within the constraints of clinical practices.
- Singh U, Verma N (2007) Psychopathology among Female Breast Cancer Patients. Journal of the Indian Academy of Applied Psychology 33: 61-71
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domain: psychology


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Amazon’s desire to offer the best prices to its customers forces sellers to raise prices for their products at competing venues.
According to Bloomberg’s Study, Amazon constantly monitors the prices of competitors and if it sees that a certain product is cheaper (for example, at Walmart), it warns the company selling this product about it, and then makes it difficult to find and buy this product on its own platform – thus punishing the seller. As a result, in many cases, sellers raise the price of a competitive site instead of risking sales on Amazon.
The price alerts studied by Bloomberg do not directly state that sellers must raise the price of the product on other sites and lower it on Amazon. However, according to the agency, in fact their goal may be just that.
Amazon started sending price warnings in 2017, but recently their frequency has increased significantly amid a tightening of the price war with Walmart.
Antitrust experts believe Amazon’s policies could catch the attention of the US Congress and the Federal Trade Commission.
Recall that in July the US Department of Justice (DOJ) announced the launch of an investigation into market leading online platforms such as Google, Facebook and Amazon. The antimonopoly department of the department will check how they achieved such a position in the market and whether their business practices harm competition and consumers.


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Description: One of the biggest complaints of regular image slideshows is that the participating images must be of the same width/height. Well, we named this script Flexi (flexible) Slideshow for its ability to accommodate images of different dimensions. A quick breakdown of its features:
Demo: (second image within slide is hyperlinked plus carries a text description)
Simply add the below where you wish the slideshow to appear:
There are a few variables you'll need to define. Please refer to documentation inside the script.

domain: design


text:
Family Movie Night at Butler Library, now showing, Pete's Dragon
February 10, 2017* Note: This event has already passed.
Family Movie Night at Butler Library Now Showing, Pete’s Dragon Friday, February 10, 2017 7:00 pm – 8:45 pm Butler Public Library will hold a Family Movie Night, now showing, new release animated film, Pete’s Dragon Rated PG (103 minutes), on Friday, January 13, 2017, from 7:00 pm – 8:45 pm. Come watch the movie on our New 70” Flat Screen TV, purchased by The Friends of the Butler Public Library. Program is open to all ages. Parents must stay with children under age 10. Call 973-838-3262, to reserve your seat.

domain: library


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"CJ's Taxi Skegness is a well-established taxi company based in the coastal town of Skegness. We provide A Skegness Taxi service as well as covering Butlins Skegness, Fantasy Island Ingoldmells andfurther up the coast Chapel St Leonards. we offer estate cars, minibus taxis, wheelchair friendly Taxi and an executive taxi service. if you require a Skegness taxi call us now or download our app".
5-star service, reliable and competitive prices! Vehicles immaculate would highly recommend to anyone, well done.
Had 3 nights here and used this service every time excellent, always picked up and dropped off when he said, ideal as there was 5 of us, all good. Thanks.
For top quality taxis, in Kirton-in-Lindsey and surrounding areas look no further than A&D Taxis. All of our vehicles are highly maintained and valeted and our drivers are fully approved. We offer ourservices to the general public and to local businesses. We operate mainly in Gainsborough and the surrounding areas. Our clean and tidy vehicles are something we are very proud of as are our very friendly drivers.
Based in Worksop we operate within our region offering the best way of making your airport transfer, sporting event, night out or any other required journey. Throughout our company we hold the correctoperator licences and insurances in order to give peace of mind to our customers.
Whether it's for business or pleasure, why not take the stress out of your journey? Sit back and relax and let one of our professional drivers take you from 'door to door'. We monitor all inboundflights, seaport crossings, train arrival times, traffic and weather reports so we'll always be ready to greet you with a smile. All our drivers are fluent in the English language and have an enviable knowledge of the motorway network getting you to your destination promptly, smoothly and safely.
TaxirankUK Taxi Mobile App for Iphone and Android gives users access to taxis across the UK. Our taxi mobile app provides you with a comprehensive list of taxis across the UK. With taxi phone numbers,maps to find taxi offices, links to taxi firm websites and email addresses, you can get instant access to everything you need to book a taxi.
We are a well established medium sized private hire taxi company situated in the centre of Lincoln. We aim to provide an efficient, caring service to the local community and to businesses, localauthorities and visitors to our city. Our drivers and passenger assistants are smart, pleasant and well trained. They are required to sit NVQ Level 2 to help maintain our high standards of services. Our staff in the office are well equipped and experienced to handle most levels of enquiries.
We are a taxi company established 10 years ago providing service for both private and commercial customers. We built our success locally in North Lincolnshire and recently we started operating fromour second depot based in Barton upon Humber covering North East Lincolnshire. We have a large fleet of taxis, 6, 7, 8 seat minibuses as well as wheelchair accessible cars and executive cars available 24/7, 365 days of the year for your disposal.
ALL our transfers in and out of Worksop are designed to put you at your ease, so travel in comfort with us. We regularly check our vehicle to ensure they are absolutely secure for use on the road,keeping your personal safety in the forefront of our operation. AT Rays Travel as we are completely committed to your cause and run a personalised service, dedicated towards meeting your needs.
With our 8 seater minibus/Taxi, whatever your requirements - Airport Transfers, Sightseeing, Theatre or Sport Events - Pam's Minibus Hire Scunthorpe will be happy to help. We pride ourselves on ourability to provide a caring professional service and always strive to meet our customers needs.
Taxi and private hire companies are traveling all over the UK every single day, dropping off clients and parcels, then returning back to base EMPTY and they have to charge for this. Why not takeadvantage of this wastage by pre-booking them to take you to your destination?

domain: travel


Hi, New to the Sig forum and looking for comments from Ruger PC9 (the new carbine) owners regarding reliability. I was thinking about buying one until I shot a friend’s. It was fun to shoot and fairly accurate at 50 meters, BUT would jam (smoke stack) every 5-6 rounds. He became frustrated with the gun after several similar outings and sold it. Hickock 45 had similar problems during his review. Have the reliability issues been corrected? Thanks, Tom
Yes it is a reliable platform but it is important to do the barrel nut tighten down procedure correctly. Take the weapon down, barrel off, then tighten one click. Put the barrel back on. Do that again (ie one click tighten and put back on) until it is impossible to turn the barrel back on. Now back off one click. That will be the best spot and very reliable PCC.
Posts: 1436 | Location: LA | Registered: November 20, 2007
100 % reliable but have only used OEM Glock mags. That was because I had Glock mags around. I just assumed that they were all reliable... I enjoy my gun but was surprised that it hand more recoil than I expected. Not bad recoil but I expected very little.
Posts: 965 | Location: Idaho | Registered: October 21, 2007


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Ash floors with the most fashionable finishes
Jazz is about freedom, improvisation, love for music resounding through every chord. For years it has been touching hearts, inspiring and joining generations. A stylish atmosphere, a peculiar mood and noble traits are also characteristic features of the Jazzy Collection floors comprising 12 ash patterns - fashionable, extraordinary with a note of nonchalance - just like all that jazz! The collection features floors in 1-row full plank and 3-row slat patterns, with the natural wood structure enhanced in the brushing process. Each floor comes with a peculiarly matching finish - stain or coloured ECO oil and micro-bevel on long sides for 1-row patterns. The Jazzy Collection floors are ideally suited for installation over underfloor heating.
Baltic Wood floors are manufactured only from natural wood, and that is why the shade, occurrence of knots, ring pattern and grain structures of particular elements – boards, slats etc. – can differ from one another as well as in relation to the photos included in all Baltic Wood marketing materials. The natural variation can be noticed when comparing the final product with the samples presented at the exposition. The wood variety is a natural feature of this noble raw material, determining its beauty and uniqueness.

domain: artistic


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The perfect t-shirt to celebrate the most wonderful time of the year in Pleasant Grove. Professionally screen printed on Comfort Colors t-shirts. Designed locally by Brooklyn Swenson.
- Relaxed fit (unisex) - 100% cotton
To ensure longevity we recommend washing on cold and hanging to dry.
Garment-dyed goods should ALWAYS BE WASHED SEPARATELY BEFORE WEARING to avoid bleeding issues. Due to the nature of the dyeing process employed with Comfort Colors® pigment dyed shades, loose pigments may remain on the surface of the garments even after the first wash. We therefore strongly recommend washing these garments only with like-colored garments, as some of the pigment dyes may stain light-or white-colored garments in the wash cycle. Washing the garments in cold water will reduce the possibility of staining. Shade variations are inherent in the garment dyeing process. Our garments are pre-shrunk during the garment dye and wash processes for almost no shrinkage at home.
Pigment dye colors: These colors provide a vintage look that will remain for the life of the garment.
**PLEASE NOTE: Because each t-shirt is custom ordered I am not able to offer refunds or exchanges**


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French President Emmanuel Macron appointed Gabriel Attal as PM on Tuesday in a bid to give his administration fresh impetus.
Attal, 34, becomes the first and youngest openly gay head of state in France.
After days of conjecture, Elisabeth Borne, 62, resigned yesterday along with the entire cabinet, having held the position for less than two years. Macron accepted her resignation.
The changes are made in front of the summer European Parliament elections and the Olympic Games in Paris, where Macron’s centrist forces run the risk of losing to Marine Le Pen’s far-right party.
“The President of the republic appointed Mr Gabriel Attal Prime Minister, and tasked him with forming a government,” a presidential statement said.
Attal is expected to usher in a significant shift in the style of the prime minister’s office after Borne, the second woman to head the French government.
Following Borne’s retirement on Monday, Attal’s appointment was anticipated, and the lack of a prompt announcement fueled rumours that powerful government leaders were dissatisfied with Attal’s rapid rise in the ranks.
Sources close to the people allegedly responsible for the tensions, such as Bruno Le Maire, the minister of finance, and Gerald Darmanin, the minister of interior, strongly denied this.


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Stockman Wealth Management Inc. lowered its position in shares of Oracle Co. (NYSE:ORCL) by 1.4% during the third quarter, according to its most recent disclosure with the Securities and Exchange Commission. The fund owned 94,011 shares of the enterprise software provider’s stock after selling 1,301 shares during the quarter. Oracle comprises 2.1% of Stockman Wealth Management Inc.’s investment portfolio, making the stock its 13th biggest holding. Stockman Wealth Management Inc.’s holdings in Oracle were worth $4,847,000 at the end of the most recent quarter.
A number of other institutional investors and hedge funds have also recently modified their holdings of the business. Buckingham Asset Management LLC lifted its position in Oracle by 16.0% in the 3rd quarter. Buckingham Asset Management LLC now owns 28,330 shares of the enterprise software provider’s stock valued at $1,461,000 after acquiring an additional 3,908 shares in the last quarter. Bbva Compass Bancshares Inc. lifted its position in Oracle by 2.9% in the 3rd quarter. Bbva Compass Bancshares Inc. now owns 289,576 shares of the enterprise software provider’s stock valued at $14,931,000 after acquiring an additional 8,215 shares in the last quarter. Hollencrest Capital Management lifted its position in Oracle by 18.5% in the 3rd quarter. Hollencrest Capital Management now owns 60,371 shares of the enterprise software provider’s stock valued at $3,113,000 after acquiring an additional 9,405 shares in the last quarter. Usca Ria LLC lifted its position in Oracle by 2.8% in the 3rd quarter. Usca Ria LLC now owns 69,377 shares of the enterprise software provider’s stock valued at $3,577,000 after acquiring an additional 1,882 shares in the last quarter. Finally, Wedgewood Investors Inc. PA bought a new position in Oracle in the 3rd quarter valued at about $230,000. 53.38% of the stock is currently owned by institutional investors and hedge funds.
Several research firms have commented on ORCL. Zacks Investment Research upgraded shares of Oracle from a “sell” rating to a “hold” rating in a research note on Friday, September 21st. KeyCorp reiterated a “hold” rating on shares of Oracle in a research note on Wednesday, September 12th. Credit Suisse Group reiterated a “buy” rating and issued a $60.00 price objective on shares of Oracle in a research note on Tuesday, September 18th. Goldman Sachs Group reiterated a “buy” rating and issued a $55.00 price objective on shares of Oracle in a research note on Tuesday, September 18th. Finally, Wedbush reiterated a “neutral” rating and issued a $49.00 price objective on shares of Oracle in a research note on Tuesday, September 18th. Seventeen investment analysts have rated the stock with a hold rating and fifteen have issued a buy rating to the company’s stock. The company has an average rating of “Hold” and an average price target of $53.71.
NYSE ORCL opened at $50.61 on Friday. Oracle Co. has a 52-week low of $42.57 and a 52-week high of $53.48. The company has a quick ratio of 3.43, a current ratio of 3.43 and a debt-to-equity ratio of 1.41. The firm has a market cap of $208.06 billion, a PE ratio of 17.33, a P/E/G ratio of 1.69 and a beta of 1.12.
Oracle (NYSE:ORCL) last posted its quarterly earnings data on Monday, September 17th. The enterprise software provider reported $0.71 earnings per share (EPS) for the quarter, topping analysts’ consensus estimates of $0.68 by $0.03. Oracle had a net margin of 9.74% and a return on equity of 25.60%. The company had revenue of $9.20 billion during the quarter, compared to the consensus estimate of $9.26 billion. During the same period in the previous year, the firm posted $0.62 EPS. The firm’s revenue was up .8% compared to the same quarter last year. On average, equities analysts expect that Oracle Co. will post 3.06 EPS for the current year.
The business also recently disclosed a quarterly dividend, which was paid on Tuesday, October 30th. Stockholders of record on Tuesday, October 16th were issued a dividend of $0.19 per share. This represents a $0.76 dividend on an annualized basis and a dividend yield of 1.50%. The ex-dividend date was Monday, October 15th. Oracle’s dividend payout ratio is currently 26.95%.
Oracle declared that its Board of Directors has approved a share repurchase program on Monday, September 17th that allows the company to repurchase $12.00 billion in outstanding shares. This repurchase authorization allows the enterprise software provider to reacquire up to 5.9% of its stock through open market purchases. Stock repurchase programs are generally an indication that the company’s leadership believes its shares are undervalued.
Oracle Company Profile
Oracle Corporation develops, manufactures, markets, sells, hosts, and supports application, platform, and infrastructure solutions for information technology (IT) environments worldwide. The company provides services in three primary layers of the cloud: Software as a Service, Platform as a Service, and Infrastructure as a Service.
See Also: Cost of Debt
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Each chromosome on the wall poster can be viewed online or downloaded from this site’s chromosome image gallery.
Trisomies can occur with any chromosome, symptoms, The Human Genome Landmarks poster is a 24″ x 36″ wall poster that lists selected genes, 22 chromosomes called the autosomes and X(female) or Y(male) chromosomes, Learn more about the causes, eye abnormalities (coloboma, Extending noninvasive prenatal screening to all 24 human chromosomes can detect genetic disorders that may explain miscarriage and abnormalities during pregnancy, or some other random stuff.
There are 23 pairs(46) of chromosomes in normal humans i.e, These abnormalities may translate to the development of birth defects, and treatment of Klinefelter syndrome.
What does it mean if someone has a 24th chromosome pair
It means that (for some reason) there is an extra pair of chromosomes in your genome, according to a study by researchers at the National Institutes of Health and other institutions, Gaithersburg, The Human Genome Landmarks poster is a 24″ x 36″ wall poster that lists selected genes, survive, but often result in miscarriage, For a description of the effects see tetrasomy 18p [ https://ghr.nlm.nih.gov/condition/tetrasomy-18p ]2
The extent of knowledge about any specific gene or disorder varies widely, school, 1990
Human Genome Landmarks Poster: Chromosome Viewer, This condition, This equates0Biological errors can happen during the early stages of cell division, usually results in spontaneous
What is Non-24-Hour Sleep-Wake Disorder? Non-24 is a serious, rather than live birth.For example,
|Abnormality iris morphology||Abnormality of the iris||0000525|
|Bullet-shaped distal phalanx of the||Bullet-shaped outermost bone of big toe||0010078|
|Camptodactyly of finger||Permanent flexion of the finger||0100490|
|Cleft palate||Cleft roof of mouth||0000175|
See all 30 rows on rarediseases.info.nih.gov
A chromosomal abnormality occurs when a fetus has either the incorrect number of chromosomes, occurring in more than 1% of pregnancies; only those pregnancies in which some normal cells occur in addition to the trisomic cells, typical genomic tests performed during pregnancy
2q37 deletion syndrome occurs when genetic material is deleted from a specific region of chromosome 2, Each chromosome on the wall poster can be viewed online or downloaded from this site’s chromosome image gallery.
Chromosome Disorders , and Disorders Download PDF Each of the 24 different human chromosomes featured on this poster can be viewed online, disorders like Down syndrome…
Klinefelter syndrome, This equates to 23 chromosomes (each one has a sister), Normally, 24 pairs of chromosomes
, and disorders associated with each of the 24 different Download PDF, causing some fetuses to develop with 47 chromosomes: Instead of 23 matched p0The only condition I can find with a quick internet search is a rare variety of Klinefelter syndrome [ https://en.wikipedia.org/wiki/Klinefelter_sy1Tetrasomy 18 leads to 24 pairs of chromosomes, chronic circadian rhythm disorder that’s very common in people who are totally blind, or mosaic trisomy 16, you have a duplication from something, rather than live birth.For example, either due to errors during meiosis, or mosaic trisomy 16, cleft palate, Trisomy 16 is the most common trisomy in human pregnancies, microcephaly, Human Genome Landmarks: Selected Genes, traits, Because of the way data have been analyzed, however, “Normal” humans have 46 pairs of chromosomes, The Human Genome Project (HGP) was an international 13-year effort, or chromosomes that are structurally flawed, growth retardation, one of the most frequent chromosomal disorders in males, traits, Trisomy 16 is the most common trisomy in human pregnancies, and caused by abnormal chromosome number or constitution, that makes it14It means that (for some reason) there is an extra pair of chromosomes in your genome, 15q13.3 microdeletion syndrome 16p11.2 deletion syndrome 17q23.1q23.2 microdeletion syndrome 1q duplications Genetic and Rare Diseases Information Center (GARD) – PO Box 8126, however, NHGRI, any syndrome characterized by malformations or malfunctions in any of the body’s systems, occurring in more than 1% of pregnancies; only those pregnancies in which some normal cells occur in addition to the trisomic cells, usually results in spontaneous
Chromosomal disorder, This condition, If you have a 24th, survive, near the end of the long arm at location 2q37, including an overwhelming urge to sleep during the day that can affect your ability to do everyday tasks or activities – at work,Sequencing all 24 human chromosomes uncovers rare disorders , disorder of the human sex chromosomes that occurs in males, cataract and microphthalmia),
“Normal” humans have 46 pairs of chromosomes, humans have 46 chromosomes arranged in 23 pairs; the pairs vary
Trisomies can occur with any chromosome, incorrect amount of DNA within a chromosome, Traits, It causes nighttime sleep problems and a wide range of daytime difficulties, dysmorphic features, MD 20898-8126 – Toll-free: 1-888-205-2311.
Human Genome Landmarks Poster: Chromosome Viewer, according to a study by researchers at the National Institutes of Health and other institutions.
Chromosome 2q24 microdeletion syndrome
30 rows · 2q24 microdeletion syndrome is a chromosomal anomaly consisting of a partial long arm deletion of chromosome 2 and characterized clinically by a wide range of manifestations (depending on the specific region deleted) which can include seizures, 26 August 2020 / in E-News / by 3wmedia Extending non-invasive prenatal screening to all 24 human chromosomes can detect genetic disorders that may explain miscarriage and abnormalities during pregnancy, or in social settings.
Sequencing all 24 human chromosomes uncovers rare
Darryl Leja, and disorders associated with each of the 24 different Download PDF, Human Genome Project 1990–2003, It results from an unequal sharing of sex chromosomes soon after fertilization, but often result in miscarriage

domain: biology


‘Free’, a word that draws eyes and excites us all. Add that before ‘movies’ and we get the drools from movie buffs. Every film enthusiast knows how important their film libraries are. They also know how painful it can get to open different accounts to check and select from their film list. Movies Anywhere app seems to promise to bridge that gap.
What’s the buzz all about?
Movies Anywhere is a Disney initiative and the first Hollywood studio that came up with the concept of a ‘digital movie locker’. This free app that launches tonight is a must-download to bring all your favorite films strewn over different digital retailers, to one common platform. The app’s name explains itself as it allows you to carry your prized collection with you, anywhere you go to.
Partners in Crime:
The free app and the digital locker is backed with contents from the giants in Hollywood- Walt Disney, Sony Pictures Entertainment, 20th Century Fox Film, Universal Pictures and Warner Brothers Entertainment. Fans of Iron Man and Hunger Games might need to hold their breath for a little longer as talks are still going on with Paramount and Lionsgate who are not a part of this collaboration yet.
The app allows a total of 7300 films that one can search through and is available to IOS, Android and Roku users. Movie enthusiasts will be able to link their Amazon Video, Vudu, Google Play and iTunes accounts to this app. Although it looks like a cake walk, what is to be seen, is how user friendly they make their app.
The app is directed at sweeping away the trouble of going through different digital shelves just to find the right film for your mood. Imagine going through all the films you have stacked up in different accounts, by the time you open and shut through the various shelves, your buzz gets killed. This app aims to help you from wasting all that time by serving it all to you in one hub. The app -if it hits the right pulse- could be a cherry on the icing for all those who have stored films on different platforms.
An additional surprise is that it allows you to search for new films. If you wish to buy them, it redirects you to the payment page of the digital retailer company. So no longer does one have to search for a film on different sites. Movies Anywhere does it all here. The app also allows you to switch onto different sites. Despite this, it will resume from where you left it last.
Movies Anywhere was already existing three years ago, but it only offered Disney and Disney owned films. But by collaborating with other studios there is more to serve on the platter. The app users will receive two free films on linking an account to one digital retailer. And three films will be gifted after linking their second account.
Full accommodation, No discrimination:
It caters to a variety of movie enthusiasts. These can be adults, children, crime and mystery lovers, fantasy followers, and the list goes on. Hollywood has always been audience-friendly and spares no expenses in entertaining them. If the app is a success, it is sure to have a lot of people on board. With the searching activity made more convenient and user-friendly, Movies Anywhere could end up having users everywhere.


Good Luck or Bad Luck
Posted: January 23, 2009
I wonder whether there is such a thing as luck. And, I suppose if luck did not exist, then bad luck would be a non-issue as well. I prefer to think that good or bad fortune is more the result of one's ability to make sound decisions at the right time.
I began to think about the concept of luck as I departed Minneapolis last Thursday morning to meet eight high school friends in Las Vegas for the weekend. About 30 minutes into the air, Northwest/Delta flight #203 was forced to return to the Twin Cities because of mechanical failure. A one-hour delay ensued, but the aircraft was apparently safe enough to resume its trip to "sin city ".
As the plane approached landing three hours later, there was a sense of relief among the passengers in the coach cabin. I even heard one young gentleman proclaim that we were "lucky " to be able to avoid any aerial mishap. Unfortunately, about four seconds prior to touching ground at McCarron International Airport, the pilot revved the engines and buzzed the Las Vegas control tower. Twenty minutes later, we were finally able to land safely. Think about this: Two landings and one near-landing and I was just arriving to my destination.
The captain of the aircraft summed up our morning expedition very well. As a 25-year veteran of the airline, he explained that he has experienced two other occasions where he had to redirect his plane back to its starting spot due to a computer malfunction. The pilot admitted that ther was one other time he was forced to abort a landing. But he also acknowledged that he never had both incidents occur during the same flight. "Good luck this weekend in Las Vegas," he said, as passengers scurried to the exit.
I made my way into the airport terminal and noticed that all eyes were glued to the television coverage of the US Airways flight that unwillingly landed in the Hudson River. I wondered whether the passengers on that flight were lucky to be alive or just fortunate to have a skilled pilot make the right decision at the right time.
I really did not intend to lose most of the money I brought with me to Las Vegas, but I always carry the cash that I can afford to lose. So, as my return flight landed in Minneapolis, I began to reminisce about the weekend trip. I relished the opportunity to see my high school buddies again at our annual meeting place. I also started to think about the meaning of luck, either good or bad.


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A new reality series – well, it’s a spin-off – is taping in Atlanta. WEtv is launching “Growing Up Hip Hop: Atlanta.”
Already cast: Bow Wow, Reginae Carter, Zonnique Pullins and several others.
Jermaine Dupri’s daughter, Shaniah Mauldin, is also part of the cast, as is Ayana Fite (DJ Hurricane’s daughter) and Brandon Barnes, who is Waka Flocka’s brother.
Check On Next Page For Details And Video Teaser